diseaseId,targetId_genename,targetId,targetFromSourceId,Max Completed Clinical Phase,Associated drugId(s),drugbank,Target/Enzyme/Transporter,Pharmacological action,Therapeutic Intent,Notes
MONDO_0007739,NDUFAB1,ENSG00000004779,O14561,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN4A,ENSG00000007314,P35499,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFS1,ENSG00000023228,P28331,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFB4,ENSG00000065518,O95168,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,DRD4,ENSG00000069696,P21917,3,CHEMBL715,DB00334,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0007739,GSK3B,ENSG00000082701,P49841,2,CHEMBL1200826,DB14509,Target,Unknown,Disease-modifying,
MONDO_0007739,NDUFB2,ENSG00000090266,O95178,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFB7,ENSG00000099795,P17568,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,HTR2A,ENSG00000102468,P28223,3,CHEMBL715,DB00334,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0007739,SLC6A2,ENSG00000103546,P23975,2,CHEMBL894,DB01156,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,GRIN2D,ENSG00000105464,O15399,2,CHEMBL807,DB01043,,,Symptomatic,
MONDO_0007739,GSK3A,ENSG00000105723,P49840,2,CHEMBL1200826,DB14509,Target,Inhibitor,Disease-modifying,
MONDO_0007739,NDUFC1,ENSG00000109390,O43677,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFS8,ENSG00000110717,O00217,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,ALDH5A1,ENSG00000112294,P51649,2,"CHEMBL109, CHEMBL2105613        ",DB00313,Target,Inhibitor,Both,
MONDO_0007739,PDE10A,ENSG00000112541,Q9Y233,2,CHEMBL562318,DB08387,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0007739,GPD2,ENSG00000115159,P43304,3,CHEMBL1431,DB00331,,Inhibitor,Disease-modifying,
MONDO_0007739,NDUFS7,ENSG00000115286,O75251,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN3B,ENSG00000116032,O60391,2,CHEMBL807,DB01043,,,Symptomatic,
MONDO_0007739,CNR1,ENSG00000118432,P21554,2,CHEMBL190461,DB09061,Target,"Antagonist, Modulator: Drug interacts directly with the target as part of its mechanism of action",Symptomatic,
MONDO_0007739,NDUFB3,ENSG00000119013,O43676,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA8,ENSG00000119421,P51970,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFAF4,ENSG00000123545,Q9P032,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA1,ENSG00000125356,O15239,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA5,ENSG00000128609,Q16718,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA10,ENSG00000130414,O95299,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA2,ENSG00000131495,O43678,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,IMPA1,ENSG00000133731,P29218,2,CHEMBL1200826,DB14509,Target,Unknown,Disease-modifying,
MONDO_0007739,NDUFB5,ENSG00000136521,O43674,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN2A,ENSG00000136531,Q99250,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,SCN7A,ENSG00000136546,Q01118,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFAF1,ENSG00000137806,Q9Y375,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA9,ENSG00000139180,Q16795,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFB10,ENSG00000140990,O96000,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SLC6A3,ENSG00000142319,Q01959,2,CHEMBL894,DB01156,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,SCN1A,ENSG00000144285,P35498,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFS6,ENSG00000145494,O75380,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFB11,ENSG00000147123,Q9NX14,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,HTR2C,ENSG00000147246,P28335,3,CHEMBL715,DB00334,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,NDUFB9,ENSG00000147684,Q9Y6M9,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,DRD2,ENSG00000149295,P14416,3,"CHEMBL596802, CHEMBL84158, CHEMBL715","DB11947, DB13025, DB00334",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Both,"(DB11947, DB13025 are both DMT)"
MONDO_0007739,NDUFC2,ENSG00000151366,O95298,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,DRD3,ENSG00000151577,P35462,3,"CHEMBL715, CHEMBL84158","DB00334, DB13025",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,SCN3A,ENSG00000153253,Q9NY46,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFS2,ENSG00000158864,O75306,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFV3,ENSG00000160194,P56181,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN2C,ENSG00000161509,Q14957,2,CHEMBL807,DB01043,,,Symptomatic,
MONDO_0007739,NDUFAF2,ENSG00000164182,Q8N183,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFS4,ENSG00000164258,O43181,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFB6,ENSG00000165264,O95139,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SLC18A2,ENSG00000165646,Q05940,4,"CHEMBL117785, CHEMBL2364639, CHEMBL3137326","DB04844, DB11915",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,NDUFB8,ENSG00000166136,O95169,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,AVPR1A,ENSG00000166148,P37288,2,CHEMBL244243,,,Antagonist,Symptomatic,
MONDO_0007739,NDUFV1,ENSG00000167792,P49821,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN11A,ENSG00000168356,Q9UI33,3,CHEMBL744,DB00740,Target,Blocker,Symptomatic,
MONDO_0007739,NDUFS5,ENSG00000168653,O43920,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN9A,ENSG00000169432,Q15858,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFA3,ENSG00000170906,O95167,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA11,ENSG00000174886,Q86Y39,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN1,ENSG00000176884,Q05586,2,CHEMBL807,DB01043,Target,Binder: This is a potential target. There are limited data regarding this target in the literature.,Symptomatic,
MONDO_0007739,NDUFAF3,ENSG00000178057,Q9BU61,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFV2,ENSG00000178127,P19404,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN2A,ENSG00000183454,Q12879,2,CHEMBL807,DB01043,,,Symptomatic,
MONDO_0007739,NDUFB1,ENSG00000183648,O75438,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN5A,ENSG00000183873,Q14524,3,CHEMBL744,DB00740,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0007739,NDUFA12,ENSG00000184752,Q9UI09,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA6,ENSG00000184983,P56556,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN10A,ENSG00000185313,Q9Y5Y9,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,NDUFA4L2,ENSG00000185633,Q9NRX3,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA13,ENSG00000186010,Q9P0J0,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,PPARA,ENSG00000186951,Q07869,2,CHEMBL672,DB01039,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0007739,SEMA4D,ENSG00000187764,Q92854,2,CHEMBL4297884,,,Inhibitor,Disease-modifying,
MONDO_0007739,NDUFA4,ENSG00000189043,O00483,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,SCN8A,ENSG00000196876,Q9UQD0,3,CHEMBL744,DB00740,,,Symptomatic,
MONDO_0007739,HTT,ENSG00000197386,ENSG00000197386,3,CHEMBL4297581,,,,Disease-modifying,
MONDO_0007739,MT-ND6,ENSG00000198695,P03923,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,MT-ND2,ENSG00000198763,P03891,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN3A,ENSG00000198785,Q8TCU5,2,CHEMBL807,DB01043,,,Symptomatic,
MONDO_0007739,MT-ND5,ENSG00000198786,P03915,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,MT-ND3,ENSG00000198840,P03897,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,MT-ND4,ENSG00000198886,P03905,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,MT-ND1,ENSG00000198888,P03886,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,MT-ND4L,ENSG00000212907,P03901,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFS3,ENSG00000213619,O75489,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,NDUFA7,ENSG00000267855,O95182,3,CHEMBL1431,DB00331,,Mitochondrial complex I (NADH dehydrogenase) inhibitor,Disease-modifying,
MONDO_0007739,GRIN2B,ENSG00000273079,Q13224,2,CHEMBL807,DB01043,,,Symptomatic,