diseaseId,targetId_genename,targetId,targetFromSourceId,Max Completed Clinical Phase,Associated drugId(s),drugbank,Target/Enzyme/Transporter,Pharmacological action,Therapeutic Intent,Notes
MONDO_0005301,SCN4A,ENSG00000007314,P35499,2,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294","DB12714, DB00740, DB00555, DB00908",,,Both,"DB00740, DB00555 for DMT"
EFO_0003929,BTK,ENSG00000010671,Q06187,3,"CHEMBL4072833, CHEMBL4650338, CHEMBL4650323       ","DB15170, DB18095",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,GABRA3,ENSG00000011677,P34903,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,POLA2,ENSG00000014138,Q14181,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0003929,GABRA1,ENSG00000022355,P14867,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNG1,ENSG00000026559,Q9UIX4,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNQ1,ENSG00000053918,P51787,4,"CHEMBL284348, CHEMBL354077, CHEMBL2107762","DB06637, DB11640, DB12714",,,Symptomatic,
MONDO_0005301,KCNH2,ENSG00000055118,Q12809,4,"CHEMBL284348, CHEMBL354077, CHEMBL2107762","DB06637, DB11640, DB12714",,,Symptomatic,
EFO_0003929,POLD1,ENSG00000062822,P28340,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0003840,PDE4A,ENSG00000065989,P27815,2,"CHEMBL19449, CHEMBL63","DB05266, DB01954",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003840,FGFR3,ENSG00000068078,P22607,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0005301,PTGS2,ENSG00000073756,P35354,3,"CHEMBL25, CHEMBL112, CHEMBL154, CHEMBL521","DB00945, DB00316, DB00788, DB01050",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNQ2,ENSG00000075043,O43526,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,TOP2B,ENSG00000077097,Q02880,2,CHEMBL44657,DB00773,Target,Inhibitor: Does NOT interact directly with target as part of MoE,Disease-modifying,
EFO_0003929,POLD3,ENSG00000077514,Q15054,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0003929,KEAP1,ENSG00000079999,Q14145,4,"CHEMBL2107333, CHEMBL3989944, CHEMBL589586","DB08908, DB14783, DB14219",Target,Binder: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,PGR,ENSG00000082175,P06401,3,CHEMBL1476022,DB13981,,,Disease-modifying,
MONDO_0005301,OPRK1,ENSG00000082556,P41145,3,CHEMBL19019,DB00704,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,ACHE,ENSG00000087085,P22303,3,CHEMBL502,DB00843,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,FKBP1A,ENSG00000088832,P62942,2,CHEMBL1201182,DB06287,,Inhibitor,Disease-modifying,
MONDO_0005301,KCNH4,ENSG00000089558,Q9UQ05,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,ESR1,ENSG00000091831,P03372,3,"CHEMBL193482, CHEMBL135","DB04573, DB00783",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,POLE2,ENSG00000100479,P56282,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0004256,PSMB5,ENSG00000100804,P28074,2,CHEMBL325041,DB00188,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,HRH3,ENSG00000101180,Q9Y5N1,2,CHEMBL3092650,DB15120,Target,Inverse agonist,Disease-modifying,
EFO_0003929,POLA1,ENSG00000101868,P09884,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0003929,TNFSF13B,ENSG00000102524,Q9Y275,2,CHEMBL1743075,,,Inhibitor,Disease-modifying,
MONDO_0005301,KCND1,ENSG00000102057,Q9NSA2,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNA7,ENSG00000104848,Q96RP8,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,GSR,ENSG00000104687,P00390,2,CHEMBL513,DB00262,Target,Allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,PTGS1,ENSG00000095303,P23219,3,"CHEMBL154, CHEMBL521, CHEMBL25, CHEMBL112","DB00788, DB01050, DB00945, DB00316",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,DHODH,ENSG00000102967,Q02127,4,"CHEMBL973, CHEMBL197194","DB08880, DB15446",Target,Inhibitor,Disease-modifying,
MONDO_0005301,SLC6A2,ENSG00000103546,P23975,3,"CHEMBL1175, CHEMBL796, CHEMBL1201222, CHEMBL1200328        ","DB00476, DB00422, DB01255",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,GRIN2D,ENSG00000105464,O15399,3,"CHEMBL660, CHEMBL1569, CHEMBL807","DB00915, DB01043",,,Symptomatic,
MONDO_0005301,PDE4C,ENSG00000105650,Q08493,2,"CHEMBL63, CHEMBL19449","DB01954, DB05266",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,ATP4A,ENSG00000105675,P20648,3,CHEMBL1503,DB00338,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,IMPDH1,ENSG00000106348,P20839,4,"CHEMBL1456, CHEMBL2106643",DB00688,Target,"Inhibitor, Inducer: Drug interacts directly with the target as part of its mechanism of action",Disease-modifying,
EFO_0003929,POLD2,ENSG00000106628,P49005,2,CHEMBL803,DB00987,,,Disease-modifying,
EFO_0004256,C5,ENSG00000106804,P01031,3,CHEMBL1201828,,,Inhibitor,Disease-modifying,
MONDO_0005301,SLC6A4,ENSG00000108576,P31645,3,"CHEMBL1200328, CHEMBL1175, CHEMBL41","DB00476, DB00472",Target,"Inhibitor, Inducer: Drug interacts directly with the target as part of its mechanism of action",Symptomatic,
MONDO_0005301,KCNA1,ENSG00000111262,Q09470,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0008522,SCNN1A,ENSG00000111319,P37088,2,CHEMBL945,DB00594,Target,"Inhibitor, Inducer: Drug interacts directly with the target as part of its mechanism of action",Disease-modifying,
MONDO_0005301,VDR,ENSG00000111424,P11473,3,"CHEMBL1536, CHEMBL1042","DB00153, DB00169",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,OPRM1,ENSG00000112038,P35372,3,CHEMBL19019,DB00704,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,IL17A,ENSG00000112115,Q16552,2,CHEMBL1743068,,,Inhibitor,Disease-modifying,
EFO_0003840,PDE10A,ENSG00000112541,Q9Y233,2,CHEMBL19449,DB05266,,,Disease-modifying,
MONDO_0005301,HMGCR,ENSG00000113161,P04035,3,"CHEMBL1064, CHEMBL1487, CHEMBL1144","DB00641, DB01076, DB00175",Target,"Inhibitor, Inducer: Drug interacts directly with the target as part of its mechanism of action",Disease-modifying,
MONDO_0005301,IL12B,ENSG00000113302,P29460,2,"CHEMBL1201835, CHEMBL1742995",,,Inhibitor,Disease-modifying,
EFO_0003929,GABRG2,ENSG00000113327,P18507,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,PDE4D,ENSG00000113448,Q08499,2,"CHEMBL63, CHEMBL19449","DB01954, DB05266",Target,Inhibitor,Disease-modifying,
MONDO_0005301,NR3C1,ENSG00000113580,P04150,4,"CHEMBL635, CHEMBL650, CHEMBL1201081, CHEMBL131, CHEMBL1201265, CHEMBL1504, CHEMBL384467, CHEMBL1201014, CHEMBL1152","DB00635, DB00959, DB00860, DB14644, DB01234, DB15566",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Both,"(CHEMBL1201081, CHEMBL1201014, DB15566 for disease modifying)       "
EFO_0003929,CD86,ENSG00000114013,P42081,2,CHEMBL1201823,,,Inhibitor,Disease-modifying,
MONDO_0005301,PDGFRB,ENSG00000113721,P09619,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0005301,ITGA4,ENSG00000115232,P13612,4,"CHEMBL2104967, CHEMBL1201607       ",DB12732,,,Both,(CHEMBL1201607	for DMT)
MONDO_0005301,GRIN3B,ENSG00000116032,O60391,3,"CHEMBL660, CHEMBL1569, CHEMBL807","DB00915, DB01043",,,Symptomatic,
MONDO_0005301,OPRD1,ENSG00000116329,P41143,3,CHEMBL19019,DB00704,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNC4,ENSG00000116396,Q03721,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,KCNQ4,ENSG00000117013,P56696,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,FAAH,ENSG00000117480,O00519,3,CHEMBL112,DB00316,Enzyme,Substrate,Symptomatic,
EFO_0003929,CSF3R,ENSG00000119535,Q99062,3,CHEMBL1201567,,,Agonist,Disease-modifying,
EFO_0003929,CD80,ENSG00000121594,P33681,2,CHEMBL1201823,,,Inhibitor,Disease-modifying,
MONDO_0005301,CCR2,ENSG00000121807,P41597,2,CHEMBL3707228,,Target,,Disease-modifying,
MONDO_0005301,KCNS1,ENSG00000124134,Q96KK3,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,S1PR4,ENSG00000125910,O95977,4,"CHEMBL314854, CHEMBL544665, CHEMBL3707375, CHEMBL3707374       ","DB08868, DB17074",Target,Modulator,Disease-modifying,
EFO_0004256,PPAT,ENSG00000128059,Q06203,3,CHEMBL1542,DB00993,Target,Inhibitor,Disease-modifying,
EFO_0003929,ADORA2A,ENSG00000128271,P29274,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNC1,ENSG00000129159,P48547,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0008522,KCNA5,ENSG00000130037,P22460,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNC3,ENSG00000131398,Q14003,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,TOP2A,ENSG00000131747,P11388,4,"CHEMBL44657, CHEMBL58, CHEMBL1417019        ","DB00773, DB01204",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,PPARG,ENSG00000132170,P37231,2,CHEMBL1236924,DB05490,Target,"Agonist, partial agonist",Disease-modifying,
MONDO_0005301,SNAP25,ENSG00000132639,P60880,3,CHEMBL1201574,,,Inhibitor,Symptomatic,
EFO_0004256,IL6ST,ENSG00000134352,P40189,4,CHEMBL3833307,,,Antagonist,Disease-modifying,
MONDO_0005301,IL2RA,ENSG00000134460,P01589,4,CHEMBL1201605,,,Inhibitor,Disease-modifying,
EFO_0003929,MTNR1B,ENSG00000134640,P49286,2,CHEMBL45,DB01065,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,PDGFRA,ENSG00000134853,P16234,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0005301,KCNH3,ENSG00000135519,Q9ULD8,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,SCN2A,ENSG00000136531,Q99250,2,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,SCN7A,ENSG00000136546,Q01118,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,GABBR2,ENSG00000136928,O75899,4,"CHEMBL701, CHEMBL2107312","DB00181, DB08892",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003840,PDE5A,ENSG00000138735,O76074,2,CHEMBL19449,DB05266,,,Disease-modifying,
MONDO_0005301,ITGB7,ENSG00000139626,P26010,2,CHEMBL2104967,DB12732,,,Disease-modifying,
EFO_0003929,ESR2,ENSG00000140009,Q92731,2,CHEMBL193482,DB04573,Target,Agonist,Disease-modifying,
MONDO_0005301,IGF1R,ENSG00000140443,P08069,2,CHEMBL1201716,,,Agonist,Disease-modifying,
MONDO_0005301,KCNH5,ENSG00000140015,Q8NCM2,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,IFNAR1,ENSG00000142166,P17181,3,"CHEMBL1201562, CHEMBL1201563, CHEMBL2108677, CHEMBL1201561        ",,,Agonist,Disease-modifying,
MONDO_0005301,SLC6A3,ENSG00000142319,Q01959,3,"CHEMBL796, CHEMBL1201222, CHEMBL1201192, CHEMBL1373","DB00422, DB01255, DB06413, DB00745",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Both,(DB06413 as DMT)
MONDO_0005301,KCNA10,ENSG00000143105,Q16322,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNH1,ENSG00000143473,O95259,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,PRIM2,ENSG00000146143,P49643,2,CHEMBL803,DB00987,,,Disease-modifying,
MONDO_0005301,SIGMAR1,ENSG00000147955,Q99720,3,CHEMBL52440,DB00514,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,POLE3,ENSG00000148229,Q9NRF9,2,CHEMBL803,DB00987,,,Disease-modifying,
MONDO_0005301,ITGB1,ENSG00000150093,P05556,2,CHEMBL2104967,DB12732,,,Disease-modifying,
EFO_0003929,DRD2,ENSG00000149295,P14416,2,CHEMBL219916,DB01184,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,GABRA2,ENSG00000151834,P47869,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,SCN1A,ENSG00000144285,P35498,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,KCNA6,ENSG00000151079,P17658,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,CACNA2D1,ENSG00000153956,P54289,2,CHEMBL940,DB00996,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,SCN3A,ENSG00000153253,Q9NY46,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,KCNS2,ENSG00000156486,Q9ULS6,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003840,MS4A1,ENSG00000156738,P11836,4,"CHEMBL2108354, CHEMBL2108041, CHEMBL1201576, CHEMBL1201836        ",,,,Disease-modifying,
MONDO_0005301,KIT,ENSG00000157404,P10721,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0005301,KCNB1,ENSG00000158445,Q14721,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,IFNAR2,ENSG00000159110,P48551,4,"CHEMBL1201562, CHEMBL1201563, CHEMBL2108677, CHEMBL1201561        ",,,Agonist,Disease-modifying,
EFO_0004256,IL6R,ENSG00000160712,P08887,4,"CHEMBL3833307, CHEMBL1237022        ",,,Antagonist,Disease-modifying,
MONDO_0005301,GRIN2C,ENSG00000161509,Q14957,3,"CHEMBL660, CHEMBL1569, CHEMBL807","DB00915, DB01043",,,Symptomatic,
MONDO_0005301,KCNF1,ENSG00000162975,Q9H3M0,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,GABRG1,ENSG00000163285,Q8N1C3,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,ADORA1,ENSG00000163485,P30542,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNV1,ENSG00000164794,Q6PIU1,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,SLC18A2,ENSG00000165646,Q05940,2,CHEMBL1201222,DB01255,,,Symptomatic,
MONDO_0005301,KCNC2,ENSG00000166006,Q96PR1,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003929,VKORC1,ENSG00000167397,Q9BQB6,3,CHEMBL1464,DB00682,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0008522,KCNV2,ENSG00000168263,Q8TDN2,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,MTNR1A,ENSG00000168412,P48039,2,CHEMBL45,DB01065,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,KCNG4,ENSG00000168418,Q8TDN1,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,SCN9A,ENSG00000169432,Q15858,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,CD52,ENSG00000169442,P31358,4,CHEMBL1201587,,,,Disease-modifying,
MONDO_0005301,LINGO1,ENSG00000169783,Q96FE5,2,CHEMBL3544922,,,Inhibitor,Disease-modifying,(No significant improvement)
EFO_0003929,ADORA2B,ENSG00000170425,P29275,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNS3,ENSG00000170745,Q9BQ31,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,KCNG3,ENSG00000171126,Q8TAE7,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,KCNH6,ENSG00000173826,Q9H252,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,SCN11A,ENSG00000168356,Q9UI33,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,S1PR1,ENSG00000170989,P21453,4,"CHEMBL314854, CHEMBL544665, CHEMBL3707374, CHEMBL3707375, CHEMBL1096146, CHEMBL2336071, CHEMBL4298150, CHEMBL3707247, CHEMBL3707246	       ","DB08868, DB17074, DB12016, DB12371, DB12612",Target,Modulator: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003840,PDE3A,ENSG00000172572,Q14432,2,CHEMBL19449,DB05266,Target,Inhibitor,Disease-modifying,
EFO_0003929,POLD4,ENSG00000175482,Q9HCU8,2,CHEMBL803,DB00987,,,Disease-modifying,
MONDO_0005301,GRIN1,ENSG00000176884,Q05586,3,"CHEMBL660, CHEMBL1569, CHEMBL807","DB00915, DB01043",,,Symptomatic,
EFO_0003929,POLE,ENSG00000177084,Q07864,2,CHEMBL803,DB00987,,,Disease-modifying,
MONDO_0005301,KCNA3,ENSG00000177272,P22001,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNA2,ENSG00000177301,P16389,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0004256,CD19,ENSG00000177455,P15391,4,CHEMBL2109334,,Target,,Disease-modifying,
MONDO_0005301,IMPDH2,ENSG00000178035,P12268,4,"CHEMBL1456, CHEMBL2106643",DB00688,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,KCNG2,ENSG00000178342,Q9UJ96,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003929,KCNA4,ENSG00000182255,P22459,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,KCNB2,ENSG00000182674,Q92953,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,S1PR5,ENSG00000180739,Q9H228,4,"CHEMBL314854, CHEMBL3707375, CHEMBL3707374, CHEMBL544665	","DB08868, DB17074",Target,Modulator: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,RGMA,ENSG00000182175,Q96B86,2,CHEMBL4297743,,Target,,Disease-modifying,
EFO_0003929,GABRG3,ENSG00000182256,Q99928,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,GRIN2A,ENSG00000183454,Q12879,3,"CHEMBL52440, CHEMBL660, CHEMBL1569, CHEMBL807","DB00514, DB00915, DB01043",,,Symptomatic,
MONDO_0005301,SCN5A,ENSG00000183873,Q14524,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,KCNH8,ENSG00000183960,Q96L42,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,KCNQ3,ENSG00000184156,O43525,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,KCND2,ENSG00000184408,Q9NZV8,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
EFO_0003840,PDE4B,ENSG00000184588,Q07343,2,"CHEMBL19449, CHEMBL63","DB05266, DB01954",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,KCNH7,ENSG00000184611,Q9NS40,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,SCN10A,ENSG00000185313,Q9Y5Y9,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,KCNQ5,ENSG00000185760,Q9NR82,4,"CHEMBL284348, CHEMBL2107762, CHEMBL354077","DB06637, DB12714, DB11640",,,Symptomatic,
MONDO_0005301,MC2R,ENSG00000185231,Q01718,4,CHEMBL1201610,,,Agonist,Symptomatic,
EFO_0003929,GABRA5,ENSG00000186297,P31644,3,CHEMBL655,DB00683,Target,Positive allosteric modulator: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,RYR1,ENSG00000196218,P21817,4,CHEMBL928,,,Antagonist,Symptomatic,
EFO_0003840,HRH1,ENSG00000196639,P35367,3,"CHEMBL17157, CHEMBL657, CHEMBL1626","DB00342, DB01075, DB00283",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
EFO_0003840,TLR7,ENSG00000196664,Q9NYK1,2,CHEMBL1535,DB01611,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,TRPV1,ENSG00000196689,Q8NER1,3,CHEMBL112,DB00316,Target,Activator,Symptomatic,
EFO_0003929,PRIM1,ENSG00000198056,P49642,2,CHEMBL803,DB00987,,,Disease-modifying,
MONDO_0005301,SCN8A,ENSG00000196876,Q9UQD0,3,"CHEMBL2107762, CHEMBL744, CHEMBL741, CHEMBL1294, CHEMBL 1068","DB12714, DB00740, DB00555, DB00908, DB00776",,,Both,"DB00740, DB00555 for DMT"
MONDO_0005301,GRIN3A,ENSG00000198785,Q8TCU5,3,"CHEMBL52440, CHEMBL660, CHEMBL1569, CHEMBL807","DB00514, DB00915, DB01043",Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,RYR3,ENSG00000198838,Q15413,4,CHEMBL928,,,Antagonist,Symptomatic,
MONDO_0005301,GABBR1,ENSG00000204681,Q9UBS5,4,"CHEMBL701, CHEMBL2107312","DB00181, DB08892",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0005301,S1PR3,ENSG00000213694,Q99500,4,"CHEMBL314854, CHEMBL3707375, CHEMBL3707374, CHEMBL544665	","DB08868, DB17074",Target,Modulator: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0005301,DHFR,ENSG00000228716,P00374,3,CHEMBL34259,DB00563,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003840,TLR9,ENSG00000239732,Q9NR96,2,CHEMBL1535,DB01611,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
EFO_0003929,ERVW-1,ENSG00000242950,Q9UQF0,2,CHEMBL4594547,,Target,,Disease-modifying,
MONDO_0005301,S1PR2,ENSG00000267534,O95136,4,"CHEMBL314854, CHEMBL3707375, CHEMBL3707374, CHEMBL544665	","DB08868, DB17074",,,Disease-modifying,
MONDO_0005301,GRIN2B,ENSG00000273079,Q13224,3,"CHEMBL660, CHEMBL1569, CHEMBL807","DB00915, DB01043",,,Symptomatic,
EFO_0003929,ADORA3,ENSG00000282608,P0DMS8,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,