complex_id,complex_name,pmid,subunits_gene_name,subunits_protein_name,functions_go_id,functions_go_name,functions_go_ontology,subunits_ensp,n_celltypes_transcriptional_coexpression,n_celltypes_structural_connectivity,n_celltypes_protein_coabundance,n_celltypes_spatial_colocalization
23,BLOC-1 (biogenesis of lysosome-related organelles complex 1),15102850,BLOC1S1;BLOC1S2;BLOC1S3;BLOC1S4;BLOC1S5;BLOC1S6;DTNBP1;SNAPIN,Biogenesis of lysosome-related organelles complex 1 subunit 1;Biogenesis of lysosome-related organelles complex 1 subunit 2;Biogenesis of lysosome-related organelles complex 1 subunit 3;Biogenesis of lysosome-related organelles complex 1 subunit 4;Biogenesis of lysosome-related organelles complex 1 subunit 5;Biogenesis of lysosome-related organelles complex 1 subunit 6;Dysbindin;SNARE-associated protein Snapin,GO:0031082,BLOC complex,cellular_component,ENSP00000447537;ENSP00000359398;ENSP00000393840;ENSP00000318128;ENSP00000380598;ENSP00000456851;ENSP00000341680;ENSP00000357674,0,0,0,0
27,Arp2/3 protein complex,9359840,ACTR2;ACTR3;ARPC1B;ARPC2;ARPC3;ARPC4;ARPC5,Actin-related protein 2;Actin-related protein 3;Actin-related protein 2/3 complex subunit 1B;Actin-related protein 2/3 complex subunit 2;Actin-related protein 2/3 complex subunit 3;Actin-related protein 2/3 complex subunit 4;Actin-related protein 2/3 complex subunit 5,GO:0005885;GO:0030833,Arp2/3 protein complex;regulation of actin filament polymerization,cellular_component;biological_process,ENSP00000367220;ENSP00000263238;ENSP00000389631;ENSP00000295685;ENSP00000228825;ENSP00000388169;ENSP00000294742,3,3,3,0
66,THRA-TRAP complex,8710870,MED1;MED12;MED14;MED16;MED17;MED24;MED25;THRA;THRAP3,Mediator of RNA polymerase II transcription subunit 1;Mediator of RNA polymerase II transcription subunit 12;Mediator of RNA polymerase II transcription subunit 14;Mediator of RNA polymerase II transcription subunit 16;Mediator of RNA polymerase II transcription subunit 17;Mediator of RNA polymerase II transcription subunit 24;Mediator of RNA polymerase II transcription subunit 25;Thyroid hormone receptor alpha;Thyroid hormone receptor-associated protein 3,GO:0005634;GO:0009755;GO:0023052;GO:0030545;GO:0045893;GO:0097067,nucleus;hormone-mediated signaling pathway;signaling;signaling receptor regulator activity;positive regulation of DNA-templated transcription;cellular response to thyroid hormone stimulus,cellular_component;biological_process;biological_process;molecular_function;biological_process;biological_process,ENSP00000300651;ENSP00000363193;ENSP00000323720;ENSP00000325612;ENSP00000251871;ENSP00000440100;ENSP00000326767;ENSP00000264637;ENSP00000346634,0,0,0,0
67,AP4 adaptor complex,10436028,AP4B1;AP4E1;AP4M1;AP4S1,AP-4 complex subunit beta-1;AP-4 complex subunit epsilon-1;AP-4 complex subunit mu-1;AP-4 complex subunit sigma-1,GO:0005515;GO:0005794;GO:0006605;GO:0006886;GO:0006892;GO:0006897;GO:0015031;GO:0016192;GO:0030133,protein binding;Golgi apparatus;protein targeting;intracellular protein transport;post-Golgi vesicle-mediated transport;endocytosis;protein transport;vesicle-mediated transport;transport vesicle,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;cellular_component,ENSP00000358582;ENSP00000261842;ENSP00000403663;ENSP00000216366,0,0,0,0
74,HOMER3-IP3R-TRPC1 complex,14505576,HOMER3;ITPR3;TRPC1,"Homer protein homolog 3;Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3;Short transient receptor potential channel 1",GO:0005216;GO:0005886;GO:0006812;GO:0008324;GO:0023052,monoatomic ion channel activity;plasma membrane;monoatomic cation transport;monoatomic cation transmembrane transporter activity;signaling,molecular_function;cellular_component;biological_process;molecular_function;biological_process,ENSP00000439937;ENSP00000363435;ENSP00000419313,0,0,0,0
100,hNURF complex,14609955,BPTF;RBBP4;RBBP7;SMARCA1,Nucleosome-remodeling factor subunit BPTF;Histone-binding protein RBBP4;Histone-binding protein RBBP7;Probable global transcription activator SNF2L1,GO:0005634;GO:0006265;GO:0006355;GO:0022008;GO:0030182;GO:0048699;GO:0051276;GO:2001141,nucleus;DNA topological change;regulation of DNA-templated transcription;neurogenesis;neuron differentiation;generation of neurons;chromosome organization;regulation of RNA biosynthetic process,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000307208;ENSP00000362592;ENSP00000369424;ENSP00000360162,0,0,0,0
140,E-box sequence-binding complex,16314316,BEX2;LDB1;LMO2;NHLH2,Protein BEX2;LIM domain-binding protein 1;Rhombotin-2;Helix-loop-helix protein 2,GO:0005634;GO:0006355;GO:0022008;GO:0048699;GO:2001141,nucleus;regulation of DNA-templated transcription;neurogenesis;generation of neurons;regulation of RNA biosynthetic process,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000442521;ENSP00000501277;ENSP00000257818;ENSP00000358519,0,0,0,0
142,BSG-gamma-secretase complex,15890777,APH1A;BSG;NCSTN;PSEN1;PSENEN,Gamma-secretase subunit APH-1A;Basigin;Nicastrin;Presenilin-1;Gamma-secretase subunit PEN-2,GO:0005794;GO:0005886;GO:0016485;GO:0023052,Golgi apparatus;plasma membrane;protein processing;signaling,cellular_component;cellular_component;biological_process;biological_process,ENSP00000358105;ENSP00000333769;ENSP00000294785;ENSP00000326366;ENSP00000468411,0,0,0,0
143,APBB1-APP695-LRP1 complex,15115822,APBB1;APP;LRP1,Amyloid beta precursor protein binding family B member 1;Amyloid-beta precursor protein;Prolow-density lipoprotein receptor-related protein 1,GO:0016485,protein processing,biological_process,ENSP00000477213;ENSP00000284981;ENSP00000243077,8,8,0,0
162,COG complex,11980916,COG1;COG2;COG3;COG4;COG5;COG6;COG7;COG8,Conserved oligomeric Golgi complex subunit 1;Conserved oligomeric Golgi complex subunit 2;Conserved oligomeric Golgi complex subunit 3;Conserved oligomeric Golgi complex subunit 4;Conserved oligomeric Golgi complex subunit 5;Conserved oligomeric Golgi complex subunit 6;Conserved oligomeric Golgi complex subunit 7;Conserved oligomeric Golgi complex subunit 8,GO:0005794;GO:0006486;GO:0007030;GO:0016192;GO:0017119,Golgi apparatus;protein glycosylation;Golgi organization;vesicle-mediated transport;Golgi transport complex,cellular_component;biological_process;biological_process;biological_process;cellular_component,ENSP00000299886;ENSP00000355629;ENSP00000258654;ENSP00000315775;ENSP00000297135;ENSP00000397441;ENSP00000305442;ENSP00000497669,0,0,0,0
186,WAVE2 complex,15070726,ABI1;BRK1;CYFIP1;NCKAP1;WASF2,Abl interactor 1;Protein BRICK1;Cytoplasmic FMR1-interacting protein 1;Nck-associated protein 1;Actin-binding protein WASF2,GO:0007264;GO:0015629;GO:0016477;GO:0030036,small GTPase-mediated signal transduction;actin cytoskeleton;cell migration;actin cytoskeleton organization,biological_process;cellular_component;biological_process;biological_process,ENSP00000365312;ENSP00000432472;ENSP00000481038;ENSP00000354251;ENSP00000483313,0,0,0,0
189,BAF complex,11078522,ACTB;ACTG1;ACTL6A;ACTL6B;ARID1A;ARID1B;SMARCA2;SMARCA4;SMARCB1;SMARCC1;SMARCC2;SMARCD1;SMARCE1,"Actin, cytoplasmic 1;Actin, cytoplasmic 2;Actin-like protein 6A;Actin-like protein 6B;AT-rich interactive domain-containing protein 1A;AT-rich interactive domain-containing protein 1B;Probable global transcription activator SNF2L2;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1",GO:0003677;GO:0005634;GO:0006265;GO:0045893;GO:0051276,DNA binding;nucleus;DNA topological change;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000494750;ENSP00000458162;ENSP00000397552;ENSP00000160382;ENSP00000320485;ENSP00000490491;ENSP00000371638;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414;ENSP00000323967,0,0,0,0
313,Cell cycle kinase complex CDK5,7903056,CCND1;CCND3;CDK5;CDKN1A;PCNA,G1/S-specific cyclin-D1;G1/S-specific cyclin-D3;Cyclin-dependent kinase 5;Cyclin-dependent kinase inhibitor 1;Proliferating cell nuclear antigen,GO:0000278;GO:0006468,mitotic cell cycle;protein phosphorylation,biological_process;biological_process,ENSP00000227507;ENSP00000362082;ENSP00000419782;ENSP00000384849;ENSP00000368458,0,0,0,0
350,DNA repair complex (PNKP-XRCC4-LigIV),15385968,LIG4;PNKP;XRCC4,DNA ligase 4;Bifunctional polynucleotide phosphatase/kinase;DNA repair protein XRCC4,GO:0003677;GO:0006281,DNA binding;DNA repair,molecular_function;biological_process,ENSP00000484288;ENSP00000323511;ENSP00000421491,0,0,0,0
390,"Ubiquitin E3 ligase (SKP1A, FBXW2, CUL1)",15640526,CUL1;FBXW2;SKP1,Cullin-1;F-box/WD repeat-containing protein 2;S-phase kinase-associated protein 1,GO:0005515;GO:0005737;GO:0006511;GO:0016567;GO:0030878;GO:0043161,protein binding;cytoplasm;ubiquitin-dependent protein catabolic process;protein ubiquitination;thyroid gland development;proteasome-mediated ubiquitin-dependent protein catabolic process,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000326804;ENSP00000476369;ENSP00000231487,0,0,0,0
432,HSPA1A-NOS1-STUB1 complex,15466472,HSPA1A;NOS1;STUB1,Heat shock 70 kDa protein 1A;Nitric oxide synthase 1;E3 ubiquitin-protein ligase CHIP,GO:0005737;GO:0006511;GO:0043161,cytoplasm;ubiquitin-dependent protein catabolic process;proteasome-mediated ubiquitin-dependent protein catabolic process,cellular_component;biological_process;biological_process,ENSP00000364802;ENSP00000477999;ENSP00000219548,9,9,0,0
462,TFTC complex (TATA-binding protein-free TAF-II-containing complex),9603525,ATXN7;KAT2A;SF3B3;SUPT3H;TADA3;TAF10;TAF12;TAF2;TAF4;TAF5;TAF5L;TAF6;TAF6L;TAF7;TAF9;TRRAP,Ataxin-7;Histone acetyltransferase KAT2A;Splicing factor 3B subunit 3;Transcription initiation protein SPT3 homolog;Transcriptional adapter 3;Transcription initiation factor TFIID subunit 10;Transcription initiation factor TFIID subunit 12;Transcription initiation factor TFIID subunit 2;Transcription initiation factor TFIID subunit 4;Transcription initiation factor TFIID subunit 5;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;Transcription initiation factor TFIID subunit 6;TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;Transcription initiation factor TFIID subunit 7;Transcription initiation factor TFIID subunit 9;Transformation/transcription domain-associated protein,GO:0004402;GO:0005634;GO:0006265;GO:0006352;GO:0045893;GO:0051276,histone acetyltransferase activity;nucleus;DNA topological change;DNA-templated transcription initiation;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000295900;ENSP00000225916;ENSP00000305790;ENSP00000360515;ENSP00000307684;ENSP00000299424;ENSP00000263974;ENSP00000367406;ENSP00000252996;ENSP00000358854;ENSP00000258281;ENSP00000399982;ENSP00000294168;ENSP00000312709;ENSP00000370193;ENSP00000352925,0,0,0,0
466,"Gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN)",15286082,APH1A;NCSTN;PSEN1;PSENEN,Gamma-secretase subunit APH-1A;Nicastrin;Presenilin-1;Gamma-secretase subunit PEN-2,GO:0005794;GO:0005886;GO:0007219;GO:0016485,Golgi apparatus;plasma membrane;Notch signaling pathway;protein processing,cellular_component;cellular_component;biological_process;biological_process,ENSP00000358105;ENSP00000294785;ENSP00000326366;ENSP00000468411,0,0,0,0
467,"Gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)",15286082,APH1B;NCSTN;PSEN2;PSENEN,Gamma-secretase subunit APH-1B;Nicastrin;Presenilin-2;Gamma-secretase subunit PEN-2,GO:0005794;GO:0005886;GO:0007219;GO:0016485;GO:0023052;GO:0051090,Golgi apparatus;plasma membrane;Notch signaling pathway;protein processing;signaling;regulation of DNA-binding transcription factor activity,cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000261879;ENSP00000294785;ENSP00000355747;ENSP00000468411,0,0,0,0
468,"Gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)",15286082,APH1A;NCSTN;PSEN2;PSENEN,Gamma-secretase subunit APH-1A;Nicastrin;Presenilin-2;Gamma-secretase subunit PEN-2,GO:0005794;GO:0005886;GO:0007219;GO:0016485;GO:0023052;GO:0051090,Golgi apparatus;plasma membrane;Notch signaling pathway;protein processing;signaling;regulation of DNA-binding transcription factor activity,cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000358105;ENSP00000294785;ENSP00000355747;ENSP00000468411,0,0,0,0
470,TFTC complex (TATA-binding protein-free TAF-II-containing complex),10591645,ATXN7;KAT2A;SF3B3;SUPT3H;TADA3;TAF10;TAF12;TAF13;TAF2;TAF4;TAF5;TAF5L;TAF6;TAF6L;TAF7;TAF9;TRRAP,Ataxin-7;Histone acetyltransferase KAT2A;Splicing factor 3B subunit 3;Transcription initiation protein SPT3 homolog;Transcriptional adapter 3;Transcription initiation factor TFIID subunit 10;Transcription initiation factor TFIID subunit 12;Transcription initiation factor TFIID subunit 13;Transcription initiation factor TFIID subunit 2;Transcription initiation factor TFIID subunit 4;Transcription initiation factor TFIID subunit 5;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;Transcription initiation factor TFIID subunit 6;TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;Transcription initiation factor TFIID subunit 7;Transcription initiation factor TFIID subunit 9;Transformation/transcription domain-associated protein,GO:0004402;GO:0005634;GO:0006265;GO:0006352;GO:0045893;GO:0051276,histone acetyltransferase activity;nucleus;DNA topological change;DNA-templated transcription initiation;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000295900;ENSP00000225916;ENSP00000305790;ENSP00000360515;ENSP00000307684;ENSP00000299424;ENSP00000263974;ENSP00000355051;ENSP00000367406;ENSP00000252996;ENSP00000358854;ENSP00000258281;ENSP00000399982;ENSP00000294168;ENSP00000312709;ENSP00000370193;ENSP00000352925,0,0,0,0
475,STAGA complex,11564863,KAT2A;SF3B3;SUPT3H;SUPT7L;TADA1;TADA3;TAF10;TAF12;TAF5L;TAF6L;TAF9;TRRAP,Histone acetyltransferase KAT2A;Splicing factor 3B subunit 3;Transcription initiation protein SPT3 homolog;STAGA complex 65 subunit gamma;Transcriptional adapter 1;Transcriptional adapter 3;Transcription initiation factor TFIID subunit 10;Transcription initiation factor TFIID subunit 12;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;Transcription initiation factor TFIID subunit 9;Transformation/transcription domain-associated protein,GO:0004402;GO:0005634;GO:0006265;GO:0006974;GO:0045893;GO:0051276,histone acetyltransferase activity;nucleus;DNA topological change;DNA damage response;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000225916;ENSP00000305790;ENSP00000360515;ENSP00000336750;ENSP00000356848;ENSP00000307684;ENSP00000299424;ENSP00000263974;ENSP00000258281;ENSP00000294168;ENSP00000370193;ENSP00000352925,0,0,0,0
476,STAGA complex,15115762,ATXN7;KAT2A;SF3B3;SUPT3H;SUPT7L;TADA1;TADA3;TAF10;TAF12;TAF5L;TAF6L;TAF9;TRRAP,Ataxin-7;Histone acetyltransferase KAT2A;Splicing factor 3B subunit 3;Transcription initiation protein SPT3 homolog;STAGA complex 65 subunit gamma;Transcriptional adapter 1;Transcriptional adapter 3;Transcription initiation factor TFIID subunit 10;Transcription initiation factor TFIID subunit 12;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;Transcription initiation factor TFIID subunit 9;Transformation/transcription domain-associated protein,GO:0004402;GO:0005634;GO:0006265;GO:0006974;GO:0045893;GO:0051276,histone acetyltransferase activity;nucleus;DNA topological change;DNA damage response;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000295900;ENSP00000225916;ENSP00000305790;ENSP00000360515;ENSP00000336750;ENSP00000356848;ENSP00000307684;ENSP00000299424;ENSP00000263974;ENSP00000258281;ENSP00000294168;ENSP00000370193;ENSP00000352925,0,0,0,0
513,TFTC complex (TATA-binding protein-free TAF-II-containing complex),15899866,ATXN7;KAT2A;SF3B3;SUPT3H;TADA3;TAF10;TAF12;TAF2;TAF4;TAF5;TAF5L;TAF6;TAF6L;TAF7;TAF9;TAF9B;TRRAP,Ataxin-7;Histone acetyltransferase KAT2A;Splicing factor 3B subunit 3;Transcription initiation protein SPT3 homolog;Transcriptional adapter 3;Transcription initiation factor TFIID subunit 10;Transcription initiation factor TFIID subunit 12;Transcription initiation factor TFIID subunit 2;Transcription initiation factor TFIID subunit 4;Transcription initiation factor TFIID subunit 5;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;Transcription initiation factor TFIID subunit 6;TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;Transcription initiation factor TFIID subunit 7;Transcription initiation factor TFIID subunit 9;Transcription initiation factor TFIID subunit 9B;Transformation/transcription domain-associated protein,GO:0005634;GO:0006265;GO:0006352;GO:0006473;GO:0045893;GO:0051276,nucleus;DNA topological change;DNA-templated transcription initiation;protein acetylation;positive regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000295900;ENSP00000225916;ENSP00000305790;ENSP00000360515;ENSP00000307684;ENSP00000299424;ENSP00000263974;ENSP00000367406;ENSP00000252996;ENSP00000358854;ENSP00000258281;ENSP00000399982;ENSP00000294168;ENSP00000312709;ENSP00000370193;ENSP00000339917;ENSP00000352925,0,0,0,0
517,AKAP5-PPP3CA-PRKAR2A complex,12507994,AKAP5;PPP3CA;PRKAR2A,A-kinase anchor protein 5;Protein phosphatase 3 catalytic subunit alpha;cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0005856;GO:0005886;GO:0006468;GO:0006470;GO:0006605;GO:0015031;GO:0019722;GO:0048167,cytoskeleton;plasma membrane;protein phosphorylation;protein dephosphorylation;protein targeting;protein transport;calcium-mediated signaling;regulation of synaptic plasticity,cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000378207;ENSP00000378323;ENSP00000265563,44,44,0,44
535,TRAP complex,10198638,CCNC;MED1;MED10;MED12;MED13;MED14;MED16;MED17;MED21;MED24;MED27;MED31;MED4;MED6;THRA;THRAP3,Cyclin-C;Mediator of RNA polymerase II transcription subunit 1;Mediator of RNA polymerase II transcription subunit 10;Mediator of RNA polymerase II transcription subunit 12;Mediator of RNA polymerase II transcription subunit 13;Mediator of RNA polymerase II transcription subunit 14;Mediator of RNA polymerase II transcription subunit 16;Mediator of RNA polymerase II transcription subunit 17;Mediator of RNA polymerase II transcription subunit 21;Mediator of RNA polymerase II transcription subunit 24;Mediator of RNA polymerase II transcription subunit 27;Mediator of RNA polymerase II transcription subunit 31;Mediator of RNA polymerase II transcription subunit 4;Mediator of RNA polymerase II transcription subunit 6;Thyroid hormone receptor alpha;Thyroid hormone receptor-associated protein 3,GO:0005634;GO:0006355;GO:0009755;GO:0023052;GO:0051090;GO:2001141,nucleus;regulation of DNA-templated transcription;hormone-mediated signaling pathway;signaling;regulation of DNA-binding transcription factor activity;regulation of RNA biosynthetic process,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000428982;ENSP00000300651;ENSP00000255764;ENSP00000363193;ENSP00000380888;ENSP00000323720;ENSP00000325612;ENSP00000251871;ENSP00000282892;ENSP00000440100;ENSP00000292035;ENSP00000225728;ENSP00000258648;ENSP00000481920;ENSP00000264637;ENSP00000346634,0,0,0,0
536,TRPC1-TRPC3-TRPC7 complex,15972814,TRPC1;TRPC3;TRPC7,Short transient receptor potential channel 1;Short transient receptor potential channel 3;Short transient receptor potential channel 7,GO:0005886;GO:0006812;GO:0008324;GO:0015267;GO:0098771,plasma membrane;monoatomic cation transport;monoatomic cation transmembrane transporter activity;channel activity;inorganic ion homeostasis,cellular_component;biological_process;molecular_function;molecular_function;biological_process,ENSP00000419313;ENSP00000368966;ENSP00000426070,0,0,0,0
552,IFNAR1-IFNAR2-IFNB1 complex,10493588,IFNAR1;IFNAR2;IFNB1,Interferon alpha/beta receptor 1;Interferon alpha/beta receptor 2;Interferon beta,GO:0019221;GO:0035456;GO:0045087;GO:0046425;GO:0051607;GO:0060337,cytokine-mediated signaling pathway;response to interferon-beta;innate immune response;regulation of receptor signaling pathway via JAK-STAT;defense response to virus;type I interferon-mediated signaling pathway,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000270139;ENSP00000343957;ENSP00000369581,0,0,0,0
555,BAF complex,11780067,ACTL6A;ARID1A;SMARCA4;SMARCB1;SMARCC1;SMARCC2;SMARCD1;SMARCD2;SMARCE1,Actin-like protein 6A;AT-rich interactive domain-containing protein 1A;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,GO:0003677;GO:0005694;GO:0006265;GO:0045893;GO:0051276,DNA binding;chromosome;DNA topological change;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000397552;ENSP00000320485;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414;ENSP00000392617;ENSP00000323967,0,0,0,0
557,TRP1-G alpha-11-IP3R3-CAV1 signaling complex,10766822,CAV1;GNA11;ITPR3;TRPC1,"Caveolin-1;Guanine nucleotide-binding protein subunit alpha-11;Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3;Short transient receptor potential channel 1",GO:0005216;GO:0005886;GO:0006812;GO:0008324;GO:0098771,monoatomic ion channel activity;plasma membrane;monoatomic cation transport;monoatomic cation transmembrane transporter activity;inorganic ion homeostasis,molecular_function;cellular_component;biological_process;molecular_function;biological_process,ENSP00000339191;ENSP00000078429;ENSP00000363435;ENSP00000419313,0,0,0,0
566,BAF complex,9845365,ACTB;ACTL6A;ARID1A;SMARCA4;SMARCB1;SMARCC1;SMARCC2;SMARCD1;SMARCE1,"Actin, cytoplasmic 1;Actin-like protein 6A;AT-rich interactive domain-containing protein 1A;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1",GO:0003677;GO:0005634;GO:0006265;GO:0045893;GO:0051276,DNA binding;nucleus;DNA topological change;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000494750;ENSP00000397552;ENSP00000320485;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414;ENSP00000323967,0,0,0,0
570,p300-CBP-p270-SWI/SNF complex,9584200,ARID1A;CREBBP;EP300;SMARCA4;SMARCB1;SMARCC1;SMARCC2,AT-rich interactive domain-containing protein 1A;CREB-binding protein;Histone acetyltransferase p300;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2,GO:0003677;GO:0005694;GO:0006265;GO:0006473;GO:0045893;GO:0051276,DNA binding;chromosome;DNA topological change;protein acetylation;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000320485;ENSP00000262367;ENSP00000263253;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396,0,0,0,0
571,p300-CBP-p270 complex,8995708,ARID1A;CREBBP;EP300,AT-rich interactive domain-containing protein 1A;CREB-binding protein;Histone acetyltransferase p300,GO:0003677;GO:0005634;GO:0045893,DNA binding;nucleus;positive regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process,ENSP00000320485;ENSP00000262367;ENSP00000263253,49,0,49,49
617,CASK-LIN7C-APBA1 complex,9822620,APBA1;CASK;LIN7C,Amyloid-beta A4 precursor protein-binding family A member 1;Peripheral plasma membrane protein CASK;Protein lin-7 homolog C,GO:0006497;GO:0006605;GO:0006886;GO:0015031,protein lipidation;protein targeting;intracellular protein transport;protein transport,biological_process;biological_process;biological_process;biological_process,ENSP00000265381;ENSP00000494788;ENSP00000278193,0,0,0,0
620,CoREST-HDAC complex,11171972,HDAC1;HDAC2;HMG20B;KDM1A;PHF21A;RCOR1;ZNF217,Histone deacetylase 1;Histone deacetylase 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;Lysine-specific histone demethylase 1A;PHD finger protein 21A;REST corepressor 1;Zinc finger protein 217,GO:0005634;GO:0006265;GO:0006476;GO:0019048;GO:0045892;GO:0051276;GO:0051607,nucleus;DNA topological change;protein deacetylation;modulation by virus of host process;negative regulation of DNA-templated transcription;chromosome organization;defense response to virus,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000362649;ENSP00000430432;ENSP00000328269;ENSP00000383042;ENSP00000398824;ENSP00000262241;ENSP00000360526,0,0,0,0
632,Anti-HDAC2 complex,12493763,CHD3;CHD4;GSE1;GTF2I;HDAC1;HDAC2;HMG20B;KDM1A;MTA1;MTA2;PHF21A;RBBP4;RBBP7;RCOR1;SIN3A;ZMYM2;ZMYM3,Chromodomain-helicase-DNA-binding protein 3;Chromodomain-helicase-DNA-binding protein 4;Genetic suppressor element 1;General transcription factor II-I;Histone deacetylase 1;Histone deacetylase 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;Lysine-specific histone demethylase 1A;Metastasis-associated protein MTA1;Metastasis-associated protein MTA2;PHD finger protein 21A;Histone-binding protein RBBP4;Histone-binding protein RBBP7;REST corepressor 1;Paired amphipathic helix protein Sin3a;Zinc finger MYM-type protein 2;Zinc finger MYM-type protein 3,GO:0005634;GO:0006265;GO:0006476;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000369716;ENSP00000440542;ENSP00000253458;ENSP00000460070;ENSP00000362649;ENSP00000430432;ENSP00000328269;ENSP00000383042;ENSP00000333633;ENSP00000278823;ENSP00000398824;ENSP00000362592;ENSP00000369424;ENSP00000262241;ENSP00000378402;ENSP00000479904;ENSP00000322845,0,0,0,0
633,anti-BHC110 complex,12493763,GSE1;GTF2I;HDAC1;HDAC2;HMG20B;KDM1A;PHF21A;RCOR1;ZMYM2;ZMYM3;ZNF217,Genetic suppressor element 1;General transcription factor II-I;Histone deacetylase 1;Histone deacetylase 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;Lysine-specific histone demethylase 1A;PHD finger protein 21A;REST corepressor 1;Zinc finger MYM-type protein 2;Zinc finger MYM-type protein 3;Zinc finger protein 217,GO:0005634;GO:0006265;GO:0006476;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000253458;ENSP00000460070;ENSP00000362649;ENSP00000430432;ENSP00000328269;ENSP00000383042;ENSP00000398824;ENSP00000262241;ENSP00000479904;ENSP00000322845;ENSP00000360526,0,0,0,0
634,XFIM complex,12493763,GTF2I;HDAC1;HDAC2;KDM1A;ZMYM3,General transcription factor II-I;Histone deacetylase 1;Histone deacetylase 2;Lysine-specific histone demethylase 1A;Zinc finger MYM-type protein 3,GO:0005634;GO:0006265;GO:0006476;GO:0032774;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;RNA biosynthetic process;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000460070;ENSP00000362649;ENSP00000430432;ENSP00000383042;ENSP00000322845,0,0,0,0
636,BHC complex,12032298,HDAC1;HDAC2;HMG20B;KDM1A;PHF21A;RCOR1,Histone deacetylase 1;Histone deacetylase 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;Lysine-specific histone demethylase 1A;PHD finger protein 21A;REST corepressor 1,GO:0005634;GO:0006265;GO:0006476;GO:0030182;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;neuron differentiation;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000362649;ENSP00000430432;ENSP00000328269;ENSP00000383042;ENSP00000398824;ENSP00000262241,0,0,0,0
649,HDAC1-associated core complex cII,11102443,CHD3;GATAD2A;HDAC1;MBD2;MBD3;MTA2;RBBP4;RBBP7;RCOR1,Chromodomain-helicase-DNA-binding protein 3;Transcriptional repressor p66-alpha;Histone deacetylase 1;Methyl-CpG-binding domain protein 2;Methyl-CpG-binding domain protein 3;Metastasis-associated protein MTA2;Histone-binding protein RBBP4;Histone-binding protein RBBP7;REST corepressor 1,GO:0003677;GO:0004407;GO:0005634;GO:0006265;GO:0045892;GO:0051276,DNA binding;histone deacetylase activity;nucleus;DNA topological change;negative regulation of DNA-templated transcription;chromosome organization,molecular_function;molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000369716;ENSP00000384899;ENSP00000362649;ENSP00000256429;ENSP00000412302;ENSP00000278823;ENSP00000362592;ENSP00000369424;ENSP00000262241,0,0,0,0
650,HDAC2-asscociated core complex,11102443,CHD3;GATAD2A;HDAC2;MBD3;MTA2;RBBP4;RBBP7,Chromodomain-helicase-DNA-binding protein 3;Transcriptional repressor p66-alpha;Histone deacetylase 2;Methyl-CpG-binding domain protein 3;Metastasis-associated protein MTA2;Histone-binding protein RBBP4;Histone-binding protein RBBP7,GO:0003677;GO:0004407;GO:0005634;GO:0006265;GO:0045892;GO:0051276,DNA binding;histone deacetylase activity;nucleus;DNA topological change;negative regulation of DNA-templated transcription;chromosome organization,molecular_function;molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000369716;ENSP00000384899;ENSP00000430432;ENSP00000412302;ENSP00000278823;ENSP00000362592;ENSP00000369424,0,0,0,0
657,"Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A)",16732284,SNX1;SNX2;VPS26A;VPS29;VPS35,Sorting nexin-1;Sorting nexin-2;Vacuolar protein sorting-associated protein 26A;Vacuolar protein sorting-associated protein 29;Vacuolar protein sorting-associated protein 35,GO:0000301;GO:0006605;GO:0006886;GO:0015031;GO:0016192;GO:0036465,"retrograde transport, vesicle recycling within Golgi;protein targeting;intracellular protein transport;protein transport;vesicle-mediated transport;synaptic vesicle recycling",biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000261889;ENSP00000368831;ENSP00000263559;ENSP00000480853;ENSP00000299138,0,0,0,0
668,ADRB2-AKAP5-KCNMA1 complex,15141163,ADRB2;AKAP5;KCNMA1,Beta-2 adrenergic receptor;A-kinase anchor protein 5;Calcium-activated potassium channel subunit alpha-1,GO:0005216;GO:0006812;GO:0006939;GO:0007186;GO:0008324;GO:0030007;GO:0050896;GO:0071875,monoatomic ion channel activity;monoatomic cation transport;smooth muscle contraction;G protein-coupled receptor signaling pathway;monoatomic cation transmembrane transporter activity;intracellular potassium ion homeostasis;response to stimulus;adrenergic receptor signaling pathway,molecular_function;biological_process;biological_process;biological_process;molecular_function;biological_process;biological_process;biological_process,ENSP00000305372;ENSP00000378207;ENSP00000286628,9,0,0,0
706,"SNARE complex (HGS, SNAP25, STX13)",14769786,HGS;SNAP25;STX12,Hepatocyte growth factor-regulated tyrosine kinase substrate;Synaptosomal-associated protein 25;Syntaxin-12,GO:0005768;GO:0006906;GO:0016079;GO:0031201;GO:0048489;GO:0061025,endosome;vesicle fusion;synaptic vesicle exocytosis;SNARE complex;synaptic vesicle transport;membrane fusion,cellular_component;biological_process;biological_process;cellular_component;biological_process;biological_process,ENSP00000331201;ENSP00000254976;ENSP00000363054,4,4,4,0
707,"SNARE complex (SNAP25, STX13, VAMP2)",14769786,SNAP25;STX12;VAMP2,Synaptosomal-associated protein 25;Syntaxin-12;Vesicle-associated membrane protein 2,GO:0031201;GO:0034058;GO:0061025,SNARE complex;endosomal vesicle fusion;membrane fusion,cellular_component;biological_process;biological_process,ENSP00000254976;ENSP00000363054;ENSP00000418572,46,46,46,0
725,P2X7 receptor signalling complex,11707406,ACTB;ACTN4;HSP90AB1;HSPA1A;HSPA8;ITGB2;LAMA3;MPP3;P2RX7;PI4KA;PTPRB;SVIL,"Actin, cytoplasmic 1;Alpha-actinin-4;Heat shock protein HSP 90-beta;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Integrin beta-2;Laminin subunit alpha-3;MAGUK p55 subfamily member 3;P2X purinoceptor 7;Phosphatidylinositol 4-kinase alpha;Receptor-type tyrosine-protein phosphatase beta;Supervillin",GO:0005216;GO:0005886;GO:0006811;GO:0007010;GO:0007166,monoatomic ion channel activity;plasma membrane;monoatomic ion transport;cytoskeleton organization;cell surface receptor signaling pathway,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000494750;ENSP00000252699;ENSP00000360609;ENSP00000364802;ENSP00000437125;ENSP00000380948;ENSP00000324532;ENSP00000381430;ENSP00000330696;ENSP00000255882;ENSP00000334928;ENSP00000348128,0,0,0,0
727,CSA complex,12732143,COPS2;COPS3;COPS4;COPS5;COPS6;COPS7A;COPS8;CUL4A;DDB1;ERCC8;GPS1;RBX1,COP9 signalosome complex subunit 2;COP9 signalosome complex subunit 3;COP9 signalosome complex subunit 4;COP9 signalosome complex subunit 5;COP9 signalosome complex subunit 6;COP9 signalosome complex subunit 7a;COP9 signalosome complex subunit 8;Cullin-4A;DNA damage-binding protein 1;DNA excision repair protein ERCC-8;COP9 signalosome complex subunit 1;E3 ubiquitin-protein ligase RBX1,GO:0005515;GO:0005634;GO:0006281;GO:0006511;GO:0006974;GO:0016567,protein binding;nucleus;DNA repair;ubiquitin-dependent protein catabolic process;DNA damage response;protein ubiquitination,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000299259;ENSP00000268717;ENSP00000424655;ENSP00000350512;ENSP00000304102;ENSP00000446039;ENSP00000346340;ENSP00000364589;ENSP00000301764;ENSP00000265038;ENSP00000376167;ENSP00000216225,0,0,0,0
730,"SNARE complex (SNAP23, STX4, VAMP1)",16920918,SNAP23;STX4;VAMP1,Synaptosomal-associated protein 23;Syntaxin-4;Vesicle-associated membrane protein 1,GO:0016079;GO:0031201;GO:0043312;GO:0048489;GO:0061025;GO:0070820;GO:0099503,synaptic vesicle exocytosis;SNARE complex;neutrophil degranulation;synaptic vesicle transport;membrane fusion;tertiary granule;secretory vesicle,biological_process;cellular_component;biological_process;biological_process;biological_process;cellular_component;cellular_component,ENSP00000249647;ENSP00000317714;ENSP00000379602,0,0,0,0
731,"SNARE complex (SNAP23, STX4, VAMP2)",16920918,SNAP23;STX4;VAMP2,Synaptosomal-associated protein 23;Syntaxin-4;Vesicle-associated membrane protein 2,GO:0006887;GO:0016079;GO:0031201;GO:0043312;GO:0061025;GO:0070820;GO:0099503,exocytosis;synaptic vesicle exocytosis;SNARE complex;neutrophil degranulation;membrane fusion;tertiary granule;secretory vesicle,biological_process;biological_process;cellular_component;biological_process;biological_process;cellular_component;cellular_component,ENSP00000249647;ENSP00000317714;ENSP00000418572,0,0,0,0
733,"SNARE complex (STX4, VAMP1, VAMP7)",16920918,STX4;VAMP1;VAMP7,Syntaxin-4;Vesicle-associated membrane protein 1;Vesicle-associated membrane protein 7,GO:0006887;GO:0006906;GO:0031201;GO:0042582;GO:0061025,exocytosis;vesicle fusion;SNARE complex;azurophil granule;membrane fusion,biological_process;biological_process;cellular_component;cellular_component;biological_process,ENSP00000317714;ENSP00000379602;ENSP00000262640,0,0,0,0
739,SIN3-ING1b complex II,11784859,ACTL6A;ARID1A;ARID4B;HDAC1;HDAC2;ING1;RBBP4;RBBP7;SAP18;SAP30;SIN3A;SMARCA4;SMARCB1;SMARCC1;SMARCC2;SMARCD1,Actin-like protein 6A;AT-rich interactive domain-containing protein 1A;AT-rich interactive domain-containing protein 4B;Histone deacetylase 1;Histone deacetylase 2;Inhibitor of growth protein 1;Histone-binding protein RBBP4;Histone-binding protein RBBP7;Histone deacetylase complex subunit SAP18;Histone deacetylase complex subunit SAP30;Paired amphipathic helix protein Sin3a;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1,GO:0004407;GO:0005634;GO:0006265;GO:0006338;GO:0045892;GO:0051090;GO:0051276,histone deacetylase activity;nucleus;DNA topological change;chromatin remodeling;negative regulation of DNA-templated transcription;regulation of DNA-binding transcription factor activity;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000397552;ENSP00000320485;ENSP00000264183;ENSP00000362649;ENSP00000430432;ENSP00000364929;ENSP00000362592;ENSP00000369424;ENSP00000481842;ENSP00000296504;ENSP00000378402;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414,0,0,0,0
741,NCOR-HDAC3 complex,11931768,GPS2;HDAC3;NCOR1;TBL1X;TBL1XR1,G protein pathway suppressor 2;Histone deacetylase 3;Nuclear receptor corepressor 1;F-box-like/WD repeat-containing protein TBL1X;F-box-like/WD repeat-containing protein TBL1XR1,GO:0005634;GO:0006265;GO:0006476;GO:0007254;GO:0032774;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;JNK cascade;RNA biosynthetic process;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000379841;ENSP00000302967;ENSP00000268712;ENSP00000495556;ENSP00000405574,0,0,0,0
749,MeCP2-SIN3A-HDAC complex,9620804,HDAC1;HDAC2;MECP2;SIN3A,Histone deacetylase 1;Histone deacetylase 2;Methyl-CpG-binding protein 2;Paired amphipathic helix protein Sin3a,GO:0003677;GO:0005634;GO:0006265;GO:0006476;GO:0045892;GO:0051276,DNA binding;nucleus;DNA topological change;protein deacetylation;negative regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000362649;ENSP00000430432;ENSP00000395535;ENSP00000378402,0,0,0,0
754,"Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14)",16209946,CASC3;EIF4A3;MAGOH;RBM8A;UPF3B,Protein CASC3;Eukaryotic initiation factor 4A-III;Protein mago nashi homolog;RNA-binding protein 8A;Regulator of nonsense transcripts 3B,GO:0003723;GO:0005634;GO:0005737;GO:0006417;GO:0043488;GO:0050658;GO:0051033;GO:0051169,RNA binding;nucleus;cytoplasm;regulation of translation;regulation of mRNA stability;RNA transport;RNA transmembrane transporter activity;nuclear transport,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process;molecular_function;biological_process,ENSP00000264645;ENSP00000497641;ENSP00000360525;ENSP00000463058;ENSP00000276201,0,0,0,0
755,"Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM)",16209946,CASC3;EIF4A3;MAGOH;PYM1;RBM8A;UPF3B,Protein CASC3;Eukaryotic initiation factor 4A-III;Protein mago nashi homolog;Partner of Y14 and mago;RNA-binding protein 8A;Regulator of nonsense transcripts 3B,GO:0003723;GO:0005634;GO:0005737;GO:0006417;GO:0043488;GO:0050658;GO:0051033;GO:0051169,RNA binding;nucleus;cytoplasm;regulation of translation;regulation of mRNA stability;RNA transport;RNA transmembrane transporter activity;nuclear transport,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process;molecular_function;biological_process,ENSP00000264645;ENSP00000497641;ENSP00000360525;ENSP00000386156;ENSP00000463058;ENSP00000276201,0,0,0,0
793,"SNARE complex (CPLX1, SNAP25, STX1A, VAMP2)",7553862,CPLX1;SNAP25;STX1A;VAMP2,Complexin-1;Synaptosomal-associated protein 25;Syntaxin-1A;Vesicle-associated membrane protein 2,GO:0005102;GO:0006906;GO:0016079;GO:0030545;GO:0031201;GO:0048489;GO:0061025,signaling receptor binding;vesicle fusion;synaptic vesicle exocytosis;signaling receptor regulator activity;SNARE complex;synaptic vesicle transport;membrane fusion,molecular_function;biological_process;biological_process;molecular_function;cellular_component;biological_process;biological_process,ENSP00000305613;ENSP00000254976;ENSP00000222812;ENSP00000418572,0,0,0,0
794,"SNARE complex (CPLX2, SNAP25, STX1a, VAMP2)",7553862,CPLX2;SNAP25;STX1A;VAMP2,Complexin-2;Synaptosomal-associated protein 25;Syntaxin-1A;Vesicle-associated membrane protein 2,GO:0005102;GO:0006906;GO:0016079;GO:0030545;GO:0031201;GO:0048489;GO:0061025,signaling receptor binding;vesicle fusion;synaptic vesicle exocytosis;signaling receptor regulator activity;SNARE complex;synaptic vesicle transport;membrane fusion,molecular_function;biological_process;biological_process;molecular_function;cellular_component;biological_process;biological_process,ENSP00000352544;ENSP00000254976;ENSP00000222812;ENSP00000418572,0,0,0,0
824,Anti-SMN protein complex,11713266,DDX20;GEMIN2;GEMIN4;SMN1;SNRPB,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Survival motor neuron protein;Small nuclear ribonucleoprotein-associated proteins B and B',GO:0005737;GO:0008380;GO:0065003,cytoplasm;RNA splicing;protein-containing complex assembly,cellular_component;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000370119;ENSP00000412566,0,0,0,0
832,Anti-Sm protein complex,11713266,CLNS1A;DDX20;GEMIN2;GEMIN4;PRMT5;SMN1;SNRPB,Methylosome subunit pICln;Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Protein arginine N-methyltransferase 5;Survival motor neuron protein;Small nuclear ribonucleoprotein-associated proteins B and B',GO:0005737;GO:0006479,cytoplasm;protein methylation,cellular_component;biological_process,ENSP00000433919;ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000319169;ENSP00000370119;ENSP00000412566,0,0,0,0
835,6S methyltransferase and RG-containing Sm proteins complex,11713266,CLNS1A;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG,Methylosome subunit pICln;Small nuclear ribonucleoprotein-associated proteins B and B';Small nuclear ribonucleoprotein Sm D1;Small nuclear ribonucleoprotein Sm D2;Small nuclear ribonucleoprotein Sm D3;Small nuclear ribonucleoprotein E;Small nuclear ribonucleoprotein F;Small nuclear ribonucleoprotein G,GO:0005737;GO:0008380,cytoplasm;RNA splicing,cellular_component;biological_process,ENSP00000433919;ENSP00000412566;ENSP00000300413;ENSP00000342374;ENSP00000215829;ENSP00000400591;ENSP00000266735;ENSP00000393388,0,0,0,0
876,"SNARE complex (STX6, VAMP3, VTI1A)",11839770,STX6;VAMP3;VTI1A,Syntaxin-6;Vesicle-associated membrane protein 3;Vesicle transport through interaction with t-SNAREs homolog 1A,GO:0006906;GO:0016079;GO:0031201;GO:0048489;GO:0061025,vesicle fusion;synaptic vesicle exocytosis;SNARE complex;synaptic vesicle transport;membrane fusion,biological_process;biological_process;cellular_component;biological_process;biological_process,ENSP00000258301;ENSP00000054666;ENSP00000376792,0,0,0,0
877,"SNARE complex (STX6, STX16, VAMP4, VTI1a, VTI1b)",11839770,STX16;STX6;VAMP4;VTI1A;VTI1B,Syntaxin-16;Syntaxin-6;Vesicle-associated membrane protein 4;Vesicle transport through interaction with t-SNAREs homolog 1A;Vesicle transport through interaction with t-SNAREs homolog 1B,GO:0006906;GO:0016079;GO:0031201;GO:0048489;GO:0061025,vesicle fusion;synaptic vesicle exocytosis;SNARE complex;synaptic vesicle transport;membrane fusion,biological_process;biological_process;cellular_component;biological_process;biological_process,ENSP00000360183;ENSP00000258301;ENSP00000236192;ENSP00000376792;ENSP00000450731,0,0,0,0
878,PKA (RII-alpha and RII-beta)-AKAP5-ADRB1 complex,16940053,ADRB1;AKAP5;PRKAR2A;PRKAR2B,Beta-1 adrenergic receptor;A-kinase anchor protein 5;cAMP-dependent protein kinase type II-alpha regulatory subunit;cAMP-dependent protein kinase type II-beta regulatory subunit,GO:0001881;GO:0007186;GO:0010737,receptor recycling;G protein-coupled receptor signaling pathway;protein kinase A signaling,biological_process;biological_process;biological_process,ENSP00000358301;ENSP00000378207;ENSP00000265563;ENSP00000265717,0,0,0,0
905,KIF3A/B-PAR-3-aPKC-PAR-6 complex,15048131,KIF3A;KIF3B;PARD3;PARD6A;PRKCI,Kinesin-like protein KIF3A;Kinesin-like protein KIF3B;Partitioning defective 3 homolog;Partitioning defective 6 homolog alpha;Protein kinase C iota type,GO:0022008;GO:0030010;GO:0030182;GO:0048699,neurogenesis;establishment of cell polarity;neuron differentiation;generation of neurons,biological_process;biological_process;biological_process;biological_process,ENSP00000385808;ENSP00000364864;ENSP00000363921;ENSP00000219255;ENSP00000295797,0,0,0,0
930,SCRIB-GIT1-ARHGEF7 complex,15182672,ARHGEF7;GIT1;SCRIB,Rho guanine nucleotide exchange factor 7;ARF GTPase-activating protein GIT1;Protein scribble homolog,GO:0005886;GO:0006887;GO:0007268;GO:0045197,plasma membrane;exocytosis;chemical synaptic transmission;establishment or maintenance of epithelial cell apical/basal polarity,cellular_component;biological_process;biological_process;biological_process,ENSP00000495631;ENSP00000378338;ENSP00000349486,0,0,0,0
999,p23 protein complex,14675759,HNRNPA2B1;PDCD6;PTGES3,Heterogeneous nuclear ribonucleoproteins A2/B1;Programmed cell death protein 6;Prostaglandin E synthase 3,GO:0005515;GO:0043067,protein binding;regulation of programmed cell death,molecular_function;biological_process,ENSP00000346694;ENSP00000264933;ENSP00000482075,9,0,0,9
1094,Frataxin complex,17331979,AFG3L2;ATP5MG;FXN;HSPA9;HSPD1;LYRM4;SDHA,"Mitochondrial inner membrane m-AAA protease component AFG3L2;ATP synthase subunit g, mitochondrial;Frataxin, mitochondrial;Stress-70 protein, mitochondrial;60 kDa heat shock protein, mitochondrial;LYR motif-containing protein 4;Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial",GO:0005515;GO:0005739,protein binding;mitochondrion,molecular_function;cellular_component,ENSP00000269143;ENSP00000300688;ENSP00000419243;ENSP00000297185;ENSP00000340019;ENSP00000443900;ENSP00000264932,0,0,0,0
1143,SMN complex (16 subunits),17178713,DDX20;GEMIN2;GEMIN4;GEMIN5;GEMIN6;GEMIN7;GEMIN8;SMN1;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;STRAP,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Gem-associated protein 5;Gem-associated protein 6;Gem-associated protein 7;Gem-associated protein 8;Survival motor neuron protein;Small nuclear ribonucleoprotein-associated proteins B and B';Small nuclear ribonucleoprotein Sm D1;Small nuclear ribonucleoprotein Sm D2;Small nuclear ribonucleoprotein Sm D3;Small nuclear ribonucleoprotein E;Small nuclear ribonucleoprotein F;Small nuclear ribonucleoprotein G;Serine-threonine kinase receptor-associated protein,GO:0003723;GO:0005634;GO:0005737;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000285873;ENSP00000281950;ENSP00000270257;ENSP00000369895;ENSP00000370119;ENSP00000412566;ENSP00000300413;ENSP00000342374;ENSP00000215829;ENSP00000400591;ENSP00000266735;ENSP00000393388;ENSP00000392270,0,0,0,0
1169,"SNARE complex (SNAP23, STX4, VAMP3)",12130530,SNAP23;STX4;VAMP3,Synaptosomal-associated protein 23;Syntaxin-4;Vesicle-associated membrane protein 3,GO:0006906;GO:0016079;GO:0031201;GO:0048489;GO:0061025,vesicle fusion;synaptic vesicle exocytosis;SNARE complex;synaptic vesicle transport;membrane fusion,biological_process;biological_process;cellular_component;biological_process;biological_process,ENSP00000249647;ENSP00000317714;ENSP00000054666,0,0,0,0
1186,ESCRT-III complex,14519844,CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3;CHMP4A;CHMP4B;CHMP4C;CHMP5;CHMP6,Charged multivesicular body protein 1a;Charged multivesicular body protein 1b;Charged multivesicular body protein 2a;Charged multivesicular body protein 2b;Charged multivesicular body protein 3;Charged multivesicular body protein 4a;Charged multivesicular body protein 4b;Charged multivesicular body protein 4c;Charged multivesicular body protein 5;Charged multivesicular body protein 6,GO:0005737;GO:0006605;GO:0006886;GO:0015031;GO:0016192,cytoplasm;protein targeting;intracellular protein transport;protein transport;vesicle-mediated transport,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000380998;ENSP00000432279;ENSP00000469240;ENSP00000263780;ENSP00000474823;ENSP00000476412;ENSP00000217402;ENSP00000297265;ENSP00000223500;ENSP00000317468,0,0,0,0
1187,ESCRT-II complex,14519844,SNF8;VPS25;VPS36,Vacuolar-sorting protein SNF8;Vacuolar protein-sorting-associated protein 25;Vacuolar protein-sorting-associated protein 36,GO:0005737;GO:0006605;GO:0006886;GO:0015031;GO:0016192,cytoplasm;protein targeting;intracellular protein transport;protein transport;vesicle-mediated transport,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000421380;ENSP00000253794;ENSP00000367299,1,1,1,0
1215,"Ubiquitin E3 ligase (FBXW7, CUL1, SKP1A, RBX1)",11585921,CUL1;FBXW7;RBX1;SKP1,Cullin-1;F-box/WD repeat-containing protein 7;E3 ubiquitin-protein ligase RBX1;S-phase kinase-associated protein 1,GO:0006511;GO:0007219;GO:0016567;GO:0023052;GO:0043161,ubiquitin-dependent protein catabolic process;Notch signaling pathway;protein ubiquitination;signaling;proteasome-mediated ubiquitin-dependent protein catabolic process,biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000326804;ENSP00000474725;ENSP00000216225;ENSP00000231487,5,5,0,5
1232,REST-CoREST-mSIN3A complex,10734093,RCOR1;REST;SIN3A,REST corepressor 1;RE1-silencing transcription factor;Paired amphipathic helix protein Sin3a,GO:0005634;GO:0007399;GO:0022008;GO:0030182;GO:0045892;GO:0048699,nucleus;nervous system development;neurogenesis;neuron differentiation;negative regulation of DNA-templated transcription;generation of neurons,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000262241;ENSP00000311816;ENSP00000378402,0,0,0,0
1237,BAF complex,11073988,ACTL6A;ARID1A;SMARCA2;SMARCA4;SMARCB1;SMARCC1;SMARCC2;SMARCD1;SMARCE1,Actin-like protein 6A;AT-rich interactive domain-containing protein 1A;Probable global transcription activator SNF2L2;Transcription activator BRG1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,GO:0003677;GO:0005634;GO:0006265;GO:0045893;GO:0051276,DNA binding;nucleus;DNA topological change;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000397552;ENSP00000320485;ENSP00000371638;ENSP00000343896;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414;ENSP00000323967,0,0,0,0
1251,BAF complex,12665591,ACTL6A;ARID1A;SMARCA2;SMARCB1;SMARCC1;SMARCC2;SMARCD1;SMARCE1,Actin-like protein 6A;AT-rich interactive domain-containing protein 1A;Probable global transcription activator SNF2L2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,GO:0003677;GO:0005694;GO:0006265;GO:0045893;GO:0051276,DNA binding;chromosome;DNA topological change;positive regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000397552;ENSP00000320485;ENSP00000371638;ENSP00000340883;ENSP00000254480;ENSP00000449396;ENSP00000378414;ENSP00000323967,0,0,0,0
1288,"DCS complex (PTBP1, PTBP2, HNRPH1, HNRPF)",11003644,HNRNPF;HNRNPH1;PTBP1;PTBP2,Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein H;Polypyrimidine tract-binding protein 1;Polypyrimidine tract-binding protein 2,GO:0003723;GO:0005634;GO:0043484;GO:0048024,"RNA binding;nucleus;regulation of RNA splicing;regulation of mRNA splicing, via spliceosome",molecular_function;cellular_component;biological_process;biological_process,ENSP00000400433;ENSP00000349168;ENSP00000349428;ENSP00000359216,1,1,0,1
1298,ARRB2-MAP2K4-MAPK10 complex,11090355,ARRB2;MAP2K4;MAPK10,Beta-arrestin-2;Dual specificity mitogen-activated protein kinase kinase 4;Mitogen-activated protein kinase 10,GO:0000165;GO:0007254;GO:0031434,MAPK cascade;JNK cascade;mitogen-activated protein kinase kinase binding,biological_process;biological_process;molecular_function,ENSP00000403701;ENSP00000410402;ENSP00000352157,0,0,0,0
1332,Large Drosha complex,15531877,DDX1;DDX17;DDX3X;DDX5;DGCR8;DHX15;DROSHA;EWSR1;FUS;HNRNPDL;HNRNPH1;HNRNPM;HNRNPU;HNRNPUL1;ILF2;ILF3;RALY;SRPK1;TAF15;TARDBP,ATP-dependent RNA helicase DDX1;Probable ATP-dependent RNA helicase DDX17;ATP-dependent RNA helicase DDX3X;Probable ATP-dependent RNA helicase DDX5;Microprocessor complex subunit DGCR8;ATP-dependent RNA helicase DHX15;Ribonuclease 3;RNA-binding protein EWS;RNA-binding protein FUS;Heterogeneous nuclear ribonucleoprotein D-like;Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein M;Heterogeneous nuclear ribonucleoprotein U;Heterogeneous nuclear ribonucleoprotein U-like protein 1;Interleukin enhancer-binding factor 2;Interleukin enhancer-binding factor 3;RNA-binding protein Raly;SRSF protein kinase 1;TATA-binding protein-associated factor 2N;TAR DNA-binding protein 43,GO:0003723;GO:0005634;GO:0006396,RNA binding;nucleus;RNA processing,molecular_function;cellular_component;biological_process,ENSP00000370745;ENSP00000380033;ENSP00000494040;ENSP00000225792;ENSP00000263209;ENSP00000336741;ENSP00000425979;ENSP00000400142;ENSP00000254108;ENSP00000483254;ENSP00000349168;ENSP00000325376;ENSP00000491215;ENSP00000375863;ENSP00000355011;ENSP00000404121;ENSP00000246194;ENSP00000362931;ENSP00000474096;ENSP00000240185,0,0,0,0
1448,LIN2-LIN7-SAP97 complex,11865057,CASK;DLG1;LIN7A,Peripheral plasma membrane protein CASK;Disks large homolog 1;Protein lin-7 homolog A,GO:0002009;GO:0006605;GO:0006886;GO:0009798;GO:0015031;GO:0030855;GO:0051211,morphogenesis of an epithelium;protein targeting;intracellular protein transport;axis specification;protein transport;epithelial cell differentiation;anisotropic cell growth,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000494788;ENSP00000345731;ENSP00000447488,0,0,0,0
1492,BHC110 complex,16079794,GSE1;HDAC1;HDAC2;HMG20B;KDM1A;PHF21A;RCOR1;ZMYM2;ZNF217;ZNF516,Genetic suppressor element 1;Histone deacetylase 1;Histone deacetylase 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;Lysine-specific histone demethylase 1A;PHD finger protein 21A;REST corepressor 1;Zinc finger MYM-type protein 2;Zinc finger protein 217;Zinc finger protein 516,GO:0005634;GO:0006265;GO:0006473;GO:0006476;GO:0006479;GO:0018126,nucleus;DNA topological change;protein acetylation;protein deacetylation;protein methylation;protein hydroxylation,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000253458;ENSP00000362649;ENSP00000430432;ENSP00000328269;ENSP00000383042;ENSP00000398824;ENSP00000262241;ENSP00000479904;ENSP00000360526;ENSP00000394757,0,0,0,0
1521,p300-SMAD1-STAT3 complex,10205054,EP300;SMAD1;STAT3,Histone acetyltransferase p300;Mothers against decapentaplegic homolog 1;Signal transducer and activator of transcription 3,GO:0007167;GO:0045893;GO:0048708,enzyme-linked receptor protein signaling pathway;positive regulation of DNA-templated transcription;astrocyte differentiation,biological_process;biological_process;biological_process,ENSP00000263253;ENSP00000305769;ENSP00000264657,7,7,0,7
1612,"Heterotrimeric G protein complex (GNG2, GNB1, GNAS)",15782186,GNAS;GNB1;GNG2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000334448,70,70,70,70
1614,GNB1-GNG2-MCF2 complex,10518015,GNB1;GNG2;MCF2,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Proto-oncogene DBL,GO:0005834,heterotrimeric G-protein complex,cellular_component,ENSP00000367872;ENSP00000334448;ENSP00000430276,0,0,0,0
1617,CACNA1A-GNB1-GNG2 complex,9238069,CACNA1A;GNB1;GNG2,Voltage-dependent P/Q-type calcium channel subunit alpha-1A;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0070588,calcium ion transmembrane transport,biological_process,ENSP00000489829;ENSP00000367872;ENSP00000334448,52,52,52,0
1729,TLE1 corepressor complex,15607978,ACTB;HSPA4;MYH10;NCL;NONO;NPM1;PARP1;RAD50;TLE1;TOP2B,"Actin, cytoplasmic 1;Heat shock 70 kDa protein 4;Myosin-10;Nucleolin;Non-POU domain-containing octamer-binding protein;Nucleophosmin;Poly [ADP-ribose] polymerase 1;DNA repair protein RAD50;Transducin-like enhancer protein 1;DNA topoisomerase 2-beta",GO:0003677;GO:0005515;GO:0005634;GO:0030182;GO:0045892;GO:0051090,DNA binding;protein binding;nucleus;neuron differentiation;negative regulation of DNA-templated transcription;regulation of DNA-binding transcription factor activity,molecular_function;molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000494750;ENSP00000302961;ENSP00000353590;ENSP00000318195;ENSP00000276079;ENSP00000296930;ENSP00000355759;ENSP00000368100;ENSP00000365682;ENSP00000264331,0,0,0,0
1745,SMN complex,11748230,DDX20;GEMIN2;GEMIN4;GEMIN5;GEMIN6;GEMIN7;SNRPA;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;SNRPN,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Gem-associated protein 5;Gem-associated protein 6;Gem-associated protein 7;U1 small nuclear ribonucleoprotein A;Small nuclear ribonucleoprotein-associated proteins B and B';Small nuclear ribonucleoprotein Sm D1;Small nuclear ribonucleoprotein Sm D2;Small nuclear ribonucleoprotein Sm D3;Small nuclear ribonucleoprotein E;Small nuclear ribonucleoprotein F;Small nuclear ribonucleoprotein G;Small nuclear ribonucleoprotein-associated protein N,GO:0003723;GO:0005634;GO:0005737;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000285873;ENSP00000281950;ENSP00000270257;ENSP00000243563;ENSP00000412566;ENSP00000300413;ENSP00000342374;ENSP00000215829;ENSP00000400591;ENSP00000266735;ENSP00000393388;ENSP00000494831,0,0,0,0
1746,SMN containing complex,11522829,GEMIN2;GEMIN4;LGALS1;LGALS3;SMN1;SNRPD1;SNRPD2;SNRPD3,Gem-associated protein 2;Gem-associated protein 4;Galectin-1;Galectin-3;Survival motor neuron protein;Small nuclear ribonucleoprotein Sm D1;Small nuclear ribonucleoprotein Sm D2;Small nuclear ribonucleoprotein Sm D3,GO:0003723;GO:0005634;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000308533;ENSP00000321706;ENSP00000215909;ENSP00000254301;ENSP00000370119;ENSP00000300413;ENSP00000342374;ENSP00000215829,0,0,0,0
1749,SMN-PolII-RHA complex,11149922,DDX20;DHX9;GEMIN2;GEMIN4;GTF2B;POLR2A;SNRPB;SNRPB2;SNRPN;TBP,Probable ATP-dependent RNA helicase DDX20;ATP-dependent RNA helicase A;Gem-associated protein 2;Gem-associated protein 4;Transcription initiation factor IIB;DNA-directed RNA polymerase II subunit RPB1;Small nuclear ribonucleoprotein-associated proteins B and B';U2 small nuclear ribonucleoprotein B'';Small nuclear ribonucleoprotein-associated protein N;TATA-box-binding protein,GO:0003723;GO:0005634;GO:0005737;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process,ENSP00000358716;ENSP00000356520;ENSP00000308533;ENSP00000321706;ENSP00000359531;ENSP00000461879;ENSP00000412566;ENSP00000246071;ENSP00000494831;ENSP00000230354,0,0,0,0
1750,PPP4C-PPP4R2-Gemin3-Gemin4 complex,12668731,DDX20;GEMIN4;PPP4C;PPP4R2,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 4;Serine/threonine-protein phosphatase 4 catalytic subunit;Serine/threonine-protein phosphatase 4 regulatory subunit 2,GO:0005634;GO:0006470,nucleus;protein dephosphorylation,cellular_component;biological_process,ENSP00000358716;ENSP00000321706;ENSP00000279387;ENSP00000349124,0,0,0,0
1751,SMN complex,15494309,DDX20;GEMIN2;GEMIN4;GEMIN5;GEMIN6;GEMIN7;SMN1;SNRPA;SNRPB;STRAP,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Gem-associated protein 5;Gem-associated protein 6;Gem-associated protein 7;Survival motor neuron protein;U1 small nuclear ribonucleoprotein A;Small nuclear ribonucleoprotein-associated proteins B and B';Serine-threonine kinase receptor-associated protein,GO:0003723;GO:0005634;GO:0005737;GO:0006811;GO:0008380;GO:0032774;GO:0050658;GO:0051033;GO:0051169;GO:0065003,RNA binding;nucleus;cytoplasm;monoatomic ion transport;RNA splicing;RNA biosynthetic process;RNA transport;RNA transmembrane transporter activity;nuclear transport;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process;molecular_function;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000285873;ENSP00000281950;ENSP00000270257;ENSP00000370119;ENSP00000243563;ENSP00000412566;ENSP00000392270,0,0,0,0
1752,SMN complex,12065586,DDX20;GEMIN2;GEMIN4;GEMIN5;GEMIN6;GEMIN7;SMN1,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Gem-associated protein 5;Gem-associated protein 6;Gem-associated protein 7;Survival motor neuron protein,GO:0003723;GO:0005634;GO:0005737;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000285873;ENSP00000281950;ENSP00000270257;ENSP00000370119,0,0,0,0
1787,Nogo-potassium channel complex,14592966,CNTNAP1;KCNA1;KCNA2;RTN4,Contactin-associated protein 1;Potassium voltage-gated channel subfamily A member 1;Potassium voltage-gated channel subfamily A member 2;Reticulon-4,GO:0005216;GO:0006812;GO:0007417;GO:0008324;GO:0022008;GO:0048699,monoatomic ion channel activity;monoatomic cation transport;central nervous system development;monoatomic cation transmembrane transporter activity;neurogenesis;generation of neurons,molecular_function;biological_process;biological_process;molecular_function;biological_process;biological_process,ENSP00000264638;ENSP00000371985;ENSP00000487785;ENSP00000337838,0,0,0,0
1793,LINGO1-NGFR-RTN4R complex,14966521,LINGO1;NGFR;RTN4R,Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1;Tumor necrosis factor receptor superfamily member 16;Reticulon-4 receptor,GO:0022008;GO:0031175;GO:0048699,neurogenesis;neuron projection development;generation of neurons,biological_process;biological_process;biological_process,ENSP00000347451;ENSP00000172229;ENSP00000043402,6,6,0,6
1795,NGF-NGFR-SORT1 complex,14985763,NGF;NGFR;SORT1,Beta-nerve growth factor;Tumor necrosis factor receptor superfamily member 16;Sortilin,GO:0006915,apoptotic process,biological_process,ENSP00000358525;ENSP00000172229;ENSP00000256637,3,3,0,0
1816,JUN-TCF4-CTNNB1 complex,16007074,CTNNB1;JUN;TCF4,Catenin beta-1;Transcription factor Jun;Transcription factor 4,GO:0016055;GO:0023052,Wnt signaling pathway;signaling,biological_process;biological_process,ENSP00000495360;ENSP00000360266;ENSP00000381382,64,0,0,0
1893,"mTOR2 complex (MTOR, RICTOR, MLST8)",15268862,MLST8;MTOR;RICTOR,Target of rapamycin complex subunit LST8;Serine/threonine-protein kinase mTOR;Rapamycin-insensitive companion of mTOR,GO:0000902;GO:0016049;GO:0030036,cell morphogenesis;cell growth;actin cytoskeleton organization,biological_process;biological_process;biological_process,ENSP00000457870;ENSP00000354558;ENSP00000296782,0,0,0,0
2124,CHUK-ESR1-NCOA3 complex,15808510,CHUK;ESR1;NCOA3,Inhibitor of nuclear factor kappa-B kinase subunit alpha;Estrogen receptor;Nuclear receptor coactivator 3,GO:0001558;GO:0003677;GO:0006355;GO:0006468;GO:0030520;GO:0032355;GO:0071391,regulation of cell growth;DNA binding;regulation of DNA-templated transcription;protein phosphorylation;estrogen receptor signaling pathway;response to estradiol;cellular response to estrogen stimulus,biological_process;molecular_function;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000359424;ENSP00000405330;ENSP00000361066,3,3,0,3
2179,CNS-P53 complex,11285227,COPS2;COPS3;COPS4;COPS5;COPS6;COPS7A;COPS8;GPS1;TP53,COP9 signalosome complex subunit 2;COP9 signalosome complex subunit 3;COP9 signalosome complex subunit 4;COP9 signalosome complex subunit 5;COP9 signalosome complex subunit 6;COP9 signalosome complex subunit 7a;COP9 signalosome complex subunit 8;COP9 signalosome complex subunit 1;Cellular tumor antigen p53,GO:0006605;GO:0006886;GO:0015031,protein targeting;intracellular protein transport;protein transport,biological_process;biological_process;biological_process,ENSP00000299259;ENSP00000268717;ENSP00000424655;ENSP00000350512;ENSP00000304102;ENSP00000446039;ENSP00000346340;ENSP00000376167;ENSP00000269305,0,0,0,0
2217,MDC1-MRN-ATM-FANCD2 complex,12607005,ATM;FANCD2;MDC1;MRE11;NBN;RAD50,Serine-protein kinase ATM;Fanconi anemia group D2 protein;Mediator of DNA damage checkpoint protein 1;Double-strand break repair protein MRE11;Nibrin;DNA repair protein RAD50,GO:0000075;GO:0003677;GO:0005634;GO:0006281;GO:0006974,cell cycle checkpoint signaling;DNA binding;nucleus;DNA repair;DNA damage response,biological_process;molecular_function;cellular_component;biological_process;biological_process,ENSP00000278616;ENSP00000287647;ENSP00000365588;ENSP00000325863;ENSP00000265433;ENSP00000368100,0,0,0,0
2241,HTT-OPTN-RAB8A complex,11137014,HTT;OPTN;RAB8A,Huntingtin;Optineurin;Ras-related protein Rab-8A,GO:0000902;GO:0016192,cell morphogenesis;vesicle-mediated transport,biological_process;biological_process,ENSP00000347184;ENSP00000368022;ENSP00000300935,1,1,0,1
2242,TGM2-HD-CALM1 complex,14985437,CALM1;HTT;TGM2,Calmodulin-1;Huntingtin;Protein-glutamine gamma-glutamyltransferase 2,GO:0065003,protein-containing complex assembly,biological_process,ENSP00000499717;ENSP00000347184;ENSP00000355330,0,0,0,0
2258,VILIP-1-AChR-alpha-4-AChR-beta-2 complex,12202488,CHRNA4;CHRNB2;VSNL1,Neuronal acetylcholine receptor subunit alpha-4;Neuronal acetylcholine receptor subunit beta-2;Visinin-like protein 1,GO:0005509;GO:0007268;GO:0051592;GO:1903048,calcium ion binding;chemical synaptic transmission;response to calcium ion;regulation of acetylcholine-gated cation channel activity,molecular_function;biological_process;biological_process;biological_process,ENSP00000359285;ENSP00000357461;ENSP00000384719,0,0,0,0
2266,PPP3CA-PPP3CB-RCAN1 complex,12809556,PPP3CA;PPP3CB;RCAN1,Protein phosphatase 3 catalytic subunit alpha;Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform;Calcipressin-1,GO:0019722,calcium-mediated signaling,biological_process,ENSP00000378323;ENSP00000378306;ENSP00000370527,22,22,22,22
2272,GRIA2-GRIP1-PICK1 complex,16055064,GRIA2;GRIP1;PICK1,Glutamate receptor 2;Glutamate receptor-interacting protein 1;PRKCA-binding protein,GO:0005886;GO:0006605;GO:0006886;GO:0006897;GO:0015031,plasma membrane;protein targeting;intracellular protein transport;endocytosis;protein transport,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000296526;ENSP00000381098;ENSP00000385205,26,26,26,0
2342,ITGAV-ITGB8-MMP14-TGFB1 complex,11970960,ITGAV;ITGB8;MMP14;TGFB1,Integrin alpha-V;Integrin beta-8;Matrix metalloproteinase-14;Transforming growth factor beta-1 proprotein,GO:0016049;GO:0032908,cell growth;regulation of transforming growth factor beta1 production,biological_process;biological_process,ENSP00000261023;ENSP00000222573;ENSP00000308208;ENSP00000221930,0,0,0,0
2401,ITGA3-ITGB1-THBS1 complex,11358957,ITGA3;ITGB1;THBS1,Integrin alpha-3;Integrin beta-1;Thrombospondin-1,GO:0007155,cell adhesion,biological_process,ENSP00000315190;ENSP00000379350;ENSP00000260356,0,0,0,0
2421,ITGA4-ITGB1-VCAM1 complex,10623819,ITGA4;ITGB1;VCAM1,Integrin alpha-4;Integrin beta-1;Vascular cell adhesion protein 1,GO:0007155,cell adhesion,biological_process,ENSP00000380227;ENSP00000379350;ENSP00000294728,11,11,0,0
2426,ITGA4-ITGB1-THBS1 complex,11980922,ITGA4;ITGB1;THBS1,Integrin alpha-4;Integrin beta-1;Thrombospondin-1,GO:0007155,cell adhesion,biological_process,ENSP00000380227;ENSP00000379350;ENSP00000260356,14,14,0,14
2428,ITGA4-ITGB1-THBS2 complex,11980922,ITGA4;ITGB1;THBS2,Integrin alpha-4;Integrin beta-1;Thrombospondin-2,GO:0007155,cell adhesion,biological_process,ENSP00000380227;ENSP00000379350;ENSP00000355751,7,7,0,7
2443,ITGA9-ITGB1-TNC complex,9565552,ITGA9;ITGB1;TNC,Integrin alpha-9;Integrin beta-1;Tenascin,GO:0005515,protein binding,molecular_function,ENSP00000264741;ENSP00000379350;ENSP00000265131,0,0,0,0
2454,CBL-EGFR-SH3GL2-SH3KBP1 complex,11894095,CBL;EGFR;SH3GL2;SH3KBP1,E3 ubiquitin-protein ligase CBL;Epidermal growth factor receptor;Endophilin-A1;SH3 domain-containing kinase-binding protein 1,GO:0006897;GO:0006900;GO:0007173;GO:0016050,endocytosis;vesicle budding from membrane;epidermal growth factor receptor signaling pathway;vesicle organization,biological_process;biological_process;biological_process;biological_process,ENSP00000264033;ENSP00000275493;ENSP00000369981;ENSP00000380921,19,19,0,0
2487,GIPC1-NTRK1-RGS19 complex,11251075,GIPC1;NTRK1;RGS19,PDZ domain-containing protein GIPC1;High affinity nerve growth factor receptor;Regulator of G-protein signaling 19,GO:0000301,"retrograde transport, vesicle recycling within Golgi",biological_process,ENSP00000376753;ENSP00000431418;ENSP00000378483,0,0,0,0
2638,HES1 promoter corepressor complex,15546612,CDK7;CREBBP;EP300;POLR2A;RBPJ;SUPT6H,Cyclin-dependent kinase 7;CREB-binding protein;Histone acetyltransferase p300;DNA-directed RNA polymerase II subunit RPB1;Recombining binding protein suppressor of hairless;Transcription elongation factor SPT6,GO:0003677;GO:0005634;GO:0045892,DNA binding;nucleus;negative regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process,ENSP00000256443;ENSP00000262367;ENSP00000263253;ENSP00000461879;ENSP00000345206;ENSP00000319104,0,0,0,0
2639,HES1 promoter-Notch enhancer complex,15546612,CCNT1;CDK7;CDK8;CDK9;EP300;INPP5K;MAML1;MED1;NOTCH1;POLR2A;RBPJ;SUPT16H;SUPT6H,Cyclin-T1;Cyclin-dependent kinase 7;Cyclin-dependent kinase 8;Cyclin-dependent kinase 9;Histone acetyltransferase p300;Inositol polyphosphate 5-phosphatase K;Mastermind-like protein 1;Mediator of RNA polymerase II transcription subunit 1;Neurogenic locus notch homolog protein 1;DNA-directed RNA polymerase II subunit RPB1;Recombining binding protein suppressor of hairless;FACT complex subunit SPT16;Transcription elongation factor SPT6,GO:0003677;GO:0005634;GO:0007219;GO:0045893,DNA binding;nucleus;Notch signaling pathway;positive regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process,ENSP00000261900;ENSP00000256443;ENSP00000370938;ENSP00000362361;ENSP00000263253;ENSP00000413937;ENSP00000292599;ENSP00000300651;ENSP00000498587;ENSP00000461879;ENSP00000345206;ENSP00000216297;ENSP00000319104,0,0,0,0
2705,CTCF-SMAD3-SMAD4 complex,12099698,CTCF;SMAD3;SMAD4,Transcriptional repressor CTCF;Mothers against decapentaplegic homolog 3;Mothers against decapentaplegic homolog 4,GO:0003677;GO:0005634;GO:0006355;GO:0007179;GO:2001141,DNA binding;nucleus;regulation of DNA-templated transcription;transforming growth factor beta receptor signaling pathway;regulation of RNA biosynthetic process,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000494538;ENSP00000332973;ENSP00000341551,5,5,0,5
2707,SMAD3-SMAD4-FOXO3-FOXG1 complex,15084259,FOXG1;FOXO3;SMAD3;SMAD4,Forkhead box protein G1;Forkhead box protein O3;Mothers against decapentaplegic homolog 3;Mothers against decapentaplegic homolog 4,GO:0003677;GO:0005634;GO:0006355;GO:0007179;GO:2001141,DNA binding;nucleus;regulation of DNA-templated transcription;transforming growth factor beta receptor signaling pathway;regulation of RNA biosynthetic process,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000339004;ENSP00000339527;ENSP00000332973;ENSP00000341551,4,4,0,0
2709,LRP1-MMP9-TIMP1 complex,11279011,LRP1;MMP9;TIMP1,Prolow-density lipoprotein receptor-related protein 1;Matrix metalloproteinase-9;Metalloproteinase inhibitor 1,GO:0006898;GO:0030198;GO:0030234;GO:0050790,receptor-mediated endocytosis;extracellular matrix organization;enzyme regulator activity;regulation of catalytic activity,biological_process;biological_process;molecular_function;biological_process,ENSP00000243077;ENSP00000361405;ENSP00000218388,0,0,0,0
2734,APH1A-PSEN1-NCSTN complex,12297508,APH1A;NCSTN;PSEN1,Gamma-secretase subunit APH-1A;Nicastrin;Presenilin-1,GO:0005886;GO:0006511;GO:0007219;GO:0043161,plasma membrane;ubiquitin-dependent protein catabolic process;Notch signaling pathway;proteasome-mediated ubiquitin-dependent protein catabolic process,cellular_component;biological_process;biological_process;biological_process,ENSP00000358105;ENSP00000294785;ENSP00000326366,0,0,0,0
2735,APH1A-PSEN2-NCSTN complex,12297508,APH1A;NCSTN;PSEN2,Gamma-secretase subunit APH-1A;Nicastrin;Presenilin-2,GO:0006511;GO:0007219;GO:0043161,ubiquitin-dependent protein catabolic process;Notch signaling pathway;proteasome-mediated ubiquitin-dependent protein catabolic process,biological_process;biological_process;biological_process,ENSP00000358105;ENSP00000294785;ENSP00000355747,2,2,0,0
2736,TROY-NGR-LINGO1 complex,15694322,LINGO1;RTN4R;TNFRSF19,Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1;Reticulon-4 receptor;Tumor necrosis factor receptor superfamily member 19,GO:0022008;GO:0031175;GO:0048699,neurogenesis;neuron projection development;generation of neurons,biological_process;biological_process;biological_process,ENSP00000347451;ENSP00000043402;ENSP00000371693,0,0,0,0
2757,"SMN complex, U7 snRNA specific",12975319,LSM10;LSM11;SNRPB;SNRPD3;SNRPE;SNRPF;SNRPG,U7 snRNA-associated Sm-like protein LSm10;U7 snRNA-associated Sm-like protein LSm11;Small nuclear ribonucleoprotein-associated proteins B and B';Small nuclear ribonucleoprotein Sm D3;Small nuclear ribonucleoprotein E;Small nuclear ribonucleoprotein F;Small nuclear ribonucleoprotein G,GO:0003723;GO:0005634;GO:0005737;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process,ENSP00000319341;ENSP00000286307;ENSP00000412566;ENSP00000215829;ENSP00000400591;ENSP00000266735;ENSP00000393388,0,0,0,0
2772,"Ubiquitin E3 ligase (CRY1, SKP1A, CUL1, FBXL3)",17463251,CRY1;CUL1;FBXL3;SKP1,Cryptochrome-1;Cullin-1;F-box/LRR-repeat protein 3;S-phase kinase-associated protein 1,GO:0005634;GO:0006511;GO:0007624;GO:0016567;GO:0043161;GO:0048511,nucleus;ubiquitin-dependent protein catabolic process;ultradian rhythm;protein ubiquitination;proteasome-mediated ubiquitin-dependent protein catabolic process;rhythmic process,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000008527;ENSP00000326804;ENSP00000347834;ENSP00000231487,0,0,0,0
2773,"Ubiquitin E3 ligase (CRY2, SKP1A, CUL1, FBXL3)",17463251,CRY2;CUL1;FBXL3;SKP1,Cryptochrome-2;Cullin-1;F-box/LRR-repeat protein 3;S-phase kinase-associated protein 1,GO:0005634;GO:0006511;GO:0007624;GO:0016567;GO:0043161;GO:0048511,nucleus;ubiquitin-dependent protein catabolic process;ultradian rhythm;protein ubiquitination;proteasome-mediated ubiquitin-dependent protein catabolic process;rhythmic process,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000478187;ENSP00000326804;ENSP00000347834;ENSP00000231487,0,0,0,0
2846,ITGAV-ITGB3-THBS1 complex,2478219,ITGAV;ITGB3;THBS1,Integrin alpha-V;Integrin beta-3;Thrombospondin-1,GO:0005515,protein binding,molecular_function,ENSP00000261023;ENSP00000452786;ENSP00000260356,0,0,0,0
2853,ITGA5-ITGB1-CAL4A3 complex,12682293,COL18A1;ITGA5;ITGB1,Collagen alpha-1(XVIII) chain;Integrin alpha-5;Integrin beta-1,GO:0006469;GO:0019210,negative regulation of protein kinase activity;kinase inhibitor activity,biological_process;molecular_function,ENSP00000352798;ENSP00000293379;ENSP00000379350,47,47,47,0
2884,"Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial",17557076,MT-ND1;NDUFA6;NDUFA9;NDUFAF1;NDUFB6;NDUFS3;NDUFS7,"NADH-ubiquinone oxidoreductase chain 1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;Complex I intermediate-associated protein 30, mitochondrial;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000354687;ENSP00000482543;ENSP00000266544;ENSP00000260361;ENSP00000369176;ENSP00000263774;ENSP00000233627,0,0,0,0
2885,ITGAV-ITGB1-SPP1 complex,7532190,ITGAV;ITGB1;SPP1,Integrin alpha-V;Integrin beta-1;Osteopontin,GO:0005515;GO:0005886;GO:0007155,protein binding;plasma membrane;cell adhesion,molecular_function;cellular_component;biological_process,ENSP00000261023;ENSP00000379350;ENSP00000378517,50,50,0,0
2890,RBPJ-NOTCH1-MAML1 complex,11997524,MAML1;NOTCH1;RBPJ,Mastermind-like protein 1;Neurogenic locus notch homolog protein 1;Recombining binding protein suppressor of hairless,GO:0003677;GO:0005634;GO:0007219;GO:0045893,DNA binding;nucleus;Notch signaling pathway;positive regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process,ENSP00000292599;ENSP00000498587;ENSP00000345206,1,1,0,1
2901,"Respiratory chain complex I (intermediate IV/310kD), mitochondrial",12941961,MT-ND1;NDUFA9;NDUFS2;NDUFS3,"NADH-ubiquinone oxidoreductase chain 1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000354687;ENSP00000266544;ENSP00000356972;ENSP00000263774,8,8,8,0
2903,"Respiratory chain complex I (intermediate V/380kD and VI/480kD), mitochondrial",12941961,MT-ND1;NDUFA2;NDUFA9;NDUFS2;NDUFS3,"NADH-ubiquinone oxidoreductase chain 1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000354687;ENSP00000252102;ENSP00000266544;ENSP00000356972;ENSP00000263774,6,6,6,0
2904,"Respiratory chain complex I (intermediate VII/650kD), mitochondrial",12941961,MT-ND1;NDUFA2;NDUFA6;NDUFA9;NDUFS2;NDUFS3;NDUFS4;NDUFS5;NDUFS7;NDUFV2,"NADH-ubiquinone oxidoreductase chain 1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 5;NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial;NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000354687;ENSP00000252102;ENSP00000482543;ENSP00000266544;ENSP00000356972;ENSP00000263774;ENSP00000296684;ENSP00000362058;ENSP00000233627;ENSP00000327268,2,2,2,0
2905,"Respiratory chain complex I (intermediate), mitochondrial",12941961,MT-ND1;NDUFA2;NDUFA6;NDUFA9;NDUFB6;NDUFS2;NDUFS3;NDUFS4;NDUFS5;NDUFS7;NDUFV2,"NADH-ubiquinone oxidoreductase chain 1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 5;NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial;NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000354687;ENSP00000252102;ENSP00000482543;ENSP00000266544;ENSP00000369176;ENSP00000356972;ENSP00000263774;ENSP00000296684;ENSP00000362058;ENSP00000233627;ENSP00000327268,1,1,1,0
2906,"Respiratory chain complex I (intermediate II/230kD), mitochondrial",12941961,NDUFS4;NDUFS7;NDUFV2,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial;NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial;NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial",GO:0005743;GO:0006119;GO:0009060;GO:0022904;GO:0065003;GO:1902600,mitochondrial inner membrane;oxidative phosphorylation;aerobic respiration;respiratory electron transport chain;protein-containing complex assembly;proton transmembrane transport,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000296684;ENSP00000233627;ENSP00000327268,121,121,121,0
2911,SMRT-SKIP-CBF1 complex,11509665,NCOR2;RBPJ;SNW1,Nuclear receptor corepressor 2;Recombining binding protein suppressor of hairless;SNW domain-containing protein 1,GO:0005634;GO:0006355;GO:0006605;GO:0006886;GO:0007219;GO:0015031;GO:2001141,nucleus;regulation of DNA-templated transcription;protein targeting;intracellular protein transport;Notch signaling pathway;protein transport;regulation of RNA biosynthetic process,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000384018;ENSP00000345206;ENSP00000451129,7,7,7,7
2931,SHARP-CtBP1-CtIP-RBP-Jkappa corepressor complex,16287852,CTBP1;RBBP8;RBPJ;SPEN,C-terminal-binding protein 1;DNA endonuclease RBBP8;Recombining binding protein suppressor of hairless;Msx2-interacting protein,GO:0003677;GO:0005634;GO:0007219;GO:0045892,DNA binding;nucleus;Notch signaling pathway;negative regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process,ENSP00000290921;ENSP00000382628;ENSP00000345206;ENSP00000364912,3,3,0,3
2944,Notch1-p56lck-PI3K complex,14583609,LCK;NOTCH1;PIK3R1,Tyrosine-protein kinase Lck;Neurogenic locus notch homolog protein 1;Phosphatidylinositol 3-kinase regulatory subunit alpha,GO:0007219;GO:0030217;GO:0043066;GO:0045893,Notch signaling pathway;T cell differentiation;negative regulation of apoptotic process;positive regulation of DNA-templated transcription,biological_process;biological_process;biological_process;biological_process,ENSP00000477713;ENSP00000498587;ENSP00000428056,24,24,0,0
2945,RBP-Jkappa-RING1-KyoT2 complex,14999091,FHL1;RBPJ;RING1,Four and a half LIM domains protein 1;Recombining binding protein suppressor of hairless;E3 ubiquitin-protein ligase RING1,GO:0003677;GO:0005515;GO:0005634;GO:0007219;GO:0045892,DNA binding;protein binding;nucleus;Notch signaling pathway;negative regulation of DNA-templated transcription,molecular_function;molecular_function;cellular_component;biological_process;biological_process,ENSP00000498684;ENSP00000345206;ENSP00000363787,0,0,0,0
2946,YY1-Notch1-RBP-Jkappa complex,12913000,NOTCH1;RBPJ;YY1,Neurogenic locus notch homolog protein 1;Recombining binding protein suppressor of hairless;Transcriptional repressor protein YY1,GO:0003677;GO:0005634;GO:0007219;GO:0045893,DNA binding;nucleus;Notch signaling pathway;positive regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process,ENSP00000498587;ENSP00000345206;ENSP00000262238,2,2,0,2
2970,"mTORC1 complex (MLST8, MTOR, RAPTOR)",15467718,MLST8;MTOR;RPTOR,Target of rapamycin complex subunit LST8;Serine/threonine-protein kinase mTOR;Regulatory-associated protein of mTOR,GO:0000902;GO:0010507;GO:0016049;GO:0019725;GO:0033554;GO:0071900,cell morphogenesis;negative regulation of autophagy;cell growth;cellular homeostasis;cellular response to stress;regulation of protein serine/threonine kinase activity,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000457870;ENSP00000354558;ENSP00000307272,1,1,1,0
2972,ITGA9-ITGB1-VEGFA complex,15590642,ITGA9;ITGB1;VEGFA,"Integrin alpha-9;Integrin beta-1;Vascular endothelial growth factor A, long form",GO:0001525,angiogenesis,biological_process,ENSP00000264741;ENSP00000379350;ENSP00000478570,0,0,0,0
2989,ITGA9-ITGB1-ADAM8 complex,16995821,ADAM8;ITGA9;ITGB1,Disintegrin and metalloproteinase domain-containing protein 8;Integrin alpha-9;Integrin beta-1,GO:0001503;GO:0005515;GO:0007155;GO:0030316,ossification;protein binding;cell adhesion;osteoclast differentiation,biological_process;molecular_function;biological_process;biological_process,ENSP00000453302;ENSP00000264741;ENSP00000379350,0,0,0,0
2998,AXIN1-CTNNB1-GSK3B-PPP2R5A complex,11818547,AXIN1;CTNNB1;GSK3B;PPP2R5A,Axin-1;Catenin beta-1;Glycogen synthase kinase-3 beta;Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform,GO:0016055,Wnt signaling pathway,biological_process,ENSP00000262320;ENSP00000495360;ENSP00000324806;ENSP00000261461,4,4,0,0
3004,APC-AXIN1-CTNNB1 complex,16188939,APC;AXIN1;CTNNB1,Adenomatous polyposis coli protein;Axin-1;Catenin beta-1,GO:0016055,Wnt signaling pathway,biological_process,ENSP00000257430;ENSP00000262320;ENSP00000495360,22,22,0,0
3082,DGCR8 multiprotein complex,17765891,DDX17;DDX5;DGCR8;DHX9;FUS;HNRNPH1;HNRNPR;HNRNPU;HSPA5;ILF3;NCL,Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5;Microprocessor complex subunit DGCR8;ATP-dependent RNA helicase A;RNA-binding protein FUS;Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein U;Endoplasmic reticulum chaperone BiP;Interleukin enhancer-binding factor 3;Nucleolin,GO:0005634;GO:0006396,nucleus;RNA processing,cellular_component;biological_process,ENSP00000380033;ENSP00000225792;ENSP00000263209;ENSP00000356520;ENSP00000254108;ENSP00000349168;ENSP00000363745;ENSP00000491215;ENSP00000324173;ENSP00000404121;ENSP00000318195,0,0,0,0
3102,DHX9-ADAR-vigilin-DNA-PK-Ku antigen complex,15723802,ADAR;DHX9;HDLBP;PRKDC;XRCC5;XRCC6,Double-stranded RNA-specific adenosine deaminase;ATP-dependent RNA helicase A;Vigilin;DNA-dependent protein kinase catalytic subunit;X-ray repair cross-complementing protein 5;X-ray repair cross-complementing protein 6,GO:0003723;GO:0005634;GO:0006265;GO:0007059;GO:0016556;GO:0051276,RNA binding;nucleus;DNA topological change;chromosome segregation;mRNA modification;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000357459;ENSP00000356520;ENSP00000375836;ENSP00000313420;ENSP00000375978;ENSP00000352257,0,0,0,0
3110,GNA12-ITGAV-P2RY2 complex,17452627,GNA12;ITGAV;P2RY2,Guanine nucleotide-binding protein subunit alpha-12;Integrin alpha-V;P2Y purinoceptor 2,GO:0005886;GO:0007186;GO:0007266;GO:0016477;GO:0035589;GO:0051492,plasma membrane;G protein-coupled receptor signaling pathway;Rho protein signal transduction;cell migration;G protein-coupled purinergic nucleotide receptor signaling pathway;regulation of stress fiber assembly,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000275364;ENSP00000261023;ENSP00000310305,0,0,0,0
3118,"SMN complex (GEMIN2, SMN1, SNRPB, SNRPDs)",9323129,GEMIN2;SMN1;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE,Gem-associated protein 2;Survival motor neuron protein;Small nuclear ribonucleoprotein-associated proteins B and B';Small nuclear ribonucleoprotein Sm D1;Small nuclear ribonucleoprotein Sm D2;Small nuclear ribonucleoprotein Sm D3;Small nuclear ribonucleoprotein E,GO:0000387;GO:0005737;GO:0034718,spliceosomal snRNP assembly;cytoplasm;SMN-Gemin2 complex,biological_process;cellular_component;cellular_component,ENSP00000308533;ENSP00000370119;ENSP00000412566;ENSP00000300413;ENSP00000342374;ENSP00000215829;ENSP00000400591,0,0,0,0
3128,"Gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)",15286082,APH1B;NCSTN;PSEN1;PSENEN,Gamma-secretase subunit APH-1B;Nicastrin;Presenilin-1;Gamma-secretase subunit PEN-2,GO:0005794;GO:0005886;GO:0007219;GO:0016485;GO:0023052;GO:0051090,Golgi apparatus;plasma membrane;Notch signaling pathway;protein processing;signaling;regulation of DNA-binding transcription factor activity,cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000261879;ENSP00000294785;ENSP00000326366;ENSP00000468411,0,0,0,0
3135,TLE1 corepressor complex,15607978,HSPA4;NCL;NONO;NPM1;PARP1;RAD50;TLE1;TOP2B,Heat shock 70 kDa protein 4;Nucleolin;Non-POU domain-containing octamer-binding protein;Nucleophosmin;Poly [ADP-ribose] polymerase 1;DNA repair protein RAD50;Transducin-like enhancer protein 1;DNA topoisomerase 2-beta,GO:0003677;GO:0005515;GO:0005634;GO:0030182;GO:0045892,DNA binding;protein binding;nucleus;neuron differentiation;negative regulation of DNA-templated transcription,molecular_function;molecular_function;cellular_component;biological_process;biological_process,ENSP00000302961;ENSP00000318195;ENSP00000276079;ENSP00000296930;ENSP00000355759;ENSP00000368100;ENSP00000365682;ENSP00000264331,0,0,0,0
3137,MASH1 promoter-coactivator complex,15607978,CREBBP;H3C1;H4C1;HES1;KAT2B;NONO;PARP1;POLR2A;SRC,CREB-binding protein;Histone H3.1;Histone H4;Transcription factor HES-1;Histone acetyltransferase KAT2B;Non-POU domain-containing octamer-binding protein;Poly [ADP-ribose] polymerase 1;DNA-directed RNA polymerase II subunit RPB1;Proto-oncogene tyrosine-protein kinase Src,GO:0003677;GO:0005634;GO:0008593;GO:0030182;GO:0045893,DNA binding;nucleus;regulation of Notch signaling pathway;neuron differentiation;positive regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000262367;ENSP00000480826;ENSP00000481486;ENSP00000232424;ENSP00000263754;ENSP00000276079;ENSP00000355759;ENSP00000461879;ENSP00000362680,0,0,0,0
3142,CAMK2-delta-MASH1 promoter-coactivator complex,15607978,CAMK2D;CREBBP;HES1;KAT2B;NONO;PARP1;POLR2A;SRC,Calcium/calmodulin-dependent protein kinase type II subunit delta;CREB-binding protein;Transcription factor HES-1;Histone acetyltransferase KAT2B;Non-POU domain-containing octamer-binding protein;Poly [ADP-ribose] polymerase 1;DNA-directed RNA polymerase II subunit RPB1;Proto-oncogene tyrosine-protein kinase Src,GO:0003677;GO:0005515;GO:0005634;GO:0008593;GO:0030182;GO:0045893,DNA binding;protein binding;nucleus;regulation of Notch signaling pathway;neuron differentiation;positive regulation of DNA-templated transcription,molecular_function;molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000425824;ENSP00000262367;ENSP00000232424;ENSP00000263754;ENSP00000276079;ENSP00000355759;ENSP00000461879;ENSP00000362680,0,0,0,0
3156,CBF1-HDAC1-SMRT complex,9694793,HDAC1;NCOR2;RBPJ,Histone deacetylase 1;Nuclear receptor corepressor 2;Recombining binding protein suppressor of hairless,GO:0005634;GO:0006265;GO:0006476;GO:0045892;GO:0051276,nucleus;DNA topological change;protein deacetylation;negative regulation of DNA-templated transcription;chromosome organization,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000362649;ENSP00000384018;ENSP00000345206,34,34,34,34
3167,NCOR-SIN3-HDAC-HESX1 complex,11731482,HDAC1;HDAC2;HESX1;NCOR2;SIN3A;SIN3B,Histone deacetylase 1;Histone deacetylase 2;Homeobox expressed in ES cells 1;Nuclear receptor corepressor 2;Paired amphipathic helix protein Sin3a;Paired amphipathic helix protein Sin3b,GO:0003677;GO:0005634;GO:0006265;GO:0006476;GO:0007219;GO:0021983;GO:0045892;GO:0051276,DNA binding;nucleus;DNA topological change;protein deacetylation;Notch signaling pathway;pituitary gland development;negative regulation of DNA-templated transcription;chromosome organization,molecular_function;cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000362649;ENSP00000430432;ENSP00000498190;ENSP00000384018;ENSP00000378402;ENSP00000369131,0,0,0,0
3207,LIN2-LIN7-SAP97-MINT1 complex,11865057,APBA1;CASK;DLG1;LIN7A,Amyloid-beta A4 precursor protein-binding family A member 1;Peripheral plasma membrane protein CASK;Disks large homolog 1;Protein lin-7 homolog A,GO:0002009;GO:0006605;GO:0006886;GO:0009798;GO:0015031;GO:0030855;GO:0051211,morphogenesis of an epithelium;protein targeting;intracellular protein transport;axis specification;protein transport;epithelial cell differentiation;anisotropic cell growth,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000265381;ENSP00000494788;ENSP00000345731;ENSP00000447488,0,0,0,0
3271,Gamma-secretase-Delta1 complex,12794186,APH1A;DLL1;NCSTN;PSEN1;PSENEN,Gamma-secretase subunit APH-1A;Delta-like protein 1;Nicastrin;Presenilin-1;Gamma-secretase subunit PEN-2,GO:0007219,Notch signaling pathway,biological_process,ENSP00000358105;ENSP00000355718;ENSP00000294785;ENSP00000326366;ENSP00000468411,0,0,0,0
3284,"SMN complex (GEMIN2, GEMIN3, GEMIN4, GEMIN5, SMN)",11714716,DDX20;GEMIN2;GEMIN4;GEMIN5;SMN1,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 2;Gem-associated protein 4;Gem-associated protein 5;Survival motor neuron protein,GO:0003723;GO:0005634;GO:0005737;GO:0006811;GO:0008380;GO:0032774;GO:0065003,RNA binding;nucleus;cytoplasm;monoatomic ion transport;RNA splicing;RNA biosynthetic process;protein-containing complex assembly,molecular_function;cellular_component;cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000358716;ENSP00000308533;ENSP00000321706;ENSP00000285873;ENSP00000370119,0,0,0,0
3296,"DDX20-GEMIN4-GEMIN5 complex, SMN-independent intermediate",17640873,DDX20;GEMIN4;GEMIN5,Probable ATP-dependent RNA helicase DDX20;Gem-associated protein 4;Gem-associated protein 5,GO:0017069;GO:0034716,snRNA binding;Gemin3-Gemin4-Gemin5 complex,molecular_function;cellular_component,ENSP00000358716;ENSP00000321706;ENSP00000285873,0,0,0,0
3297,"GEMIN6-GEMIN7-STRAP complex, SMN-independent intermediate",17640873,GEMIN6;GEMIN7;STRAP,Gem-associated protein 6;Gem-associated protein 7;Serine-threonine kinase receptor-associated protein,GO:0005737;GO:0034717,cytoplasm;Gemin6-Gemin7-unrip complex,cellular_component;cellular_component,ENSP00000281950;ENSP00000270257;ENSP00000392270,0,0,0,0
3298,"SMN complex (GEMIN2, GEMIN5, SMN1)",17640873,GEMIN2;GEMIN5;SMN1,Gem-associated protein 2;Gem-associated protein 5;Survival motor neuron protein,GO:0005737;GO:0032797;GO:0034718,cytoplasm;SMN complex;SMN-Gemin2 complex,cellular_component;cellular_component;cellular_component,ENSP00000308533;ENSP00000285873;ENSP00000370119,1,1,0,1
3979,"mTORC2 complex  (MAPKAP1, MLST8, MTOR, RICTOR)",17043309,MAPKAP1;MLST8;MTOR;RICTOR,Target of rapamycin complex 2 subunit MAPKAP1;Target of rapamycin complex subunit LST8;Serine/threonine-protein kinase mTOR;Rapamycin-insensitive companion of mTOR,GO:0000902;GO:0016049;GO:0030036;GO:0051896,cell morphogenesis;cell growth;actin cytoskeleton organization;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process;biological_process;biological_process;biological_process,ENSP00000265960;ENSP00000457870;ENSP00000354558;ENSP00000296782,0,0,0,0
4151,"TSC (TSC1, TSC2, AXIN, GSK3) complex",15972957,AXIN1;GSK3B;TSC1;TSC2,Axin-1;Glycogen synthase kinase-3 beta;Hamartin;Tuberin,GO:0009299;GO:0030111;GO:0033596;GO:1904713,mRNA transcription;regulation of Wnt signaling pathway;TSC1-TSC2 complex;beta-catenin destruction complex binding,biological_process;biological_process;cellular_component;molecular_function,ENSP00000262320;ENSP00000324806;ENSP00000298552;ENSP00000219476,3,3,0,0
4158,CALM1-FKBP8-HSP90AA1 complex,17379601,CALM1;FKBP8;HSP90AA1,Calmodulin-1;Peptidyl-prolyl cis-trans isomerase FKBP8;Heat shock protein HSP 90-alpha,GO:0043067,regulation of programmed cell death,biological_process,ENSP00000499717;ENSP00000471700;ENSP00000335153,0,0,0,0
4869,beta(1)-AR receptosome (ADRB1-SAP97-AKAP79-PRKAR2A),17170109,ADRB1;AKAP5;DLG1;PRKAR2A,Beta-1 adrenergic receptor;A-kinase anchor protein 5;Disks large homolog 1;cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0001881;GO:0006468;GO:0006605;GO:0007186,receptor recycling;protein phosphorylation;protein targeting;G protein-coupled receptor signaling pathway,biological_process;biological_process;biological_process;biological_process,ENSP00000358301;ENSP00000378207;ENSP00000345731;ENSP00000265563,12,0,0,0
5184,SWI/SNF-related chromatin-remodeling complex,15696166,HDAC1;MECP2;SIN3A;SMARCA2;SMARCE1,Histone deacetylase 1;Methyl-CpG-binding protein 2;Paired amphipathic helix protein Sin3a;Probable global transcription activator SNF2L2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,GO:0006338;GO:0045892,chromatin remodeling;negative regulation of DNA-templated transcription,biological_process;biological_process,ENSP00000362649;ENSP00000395535;ENSP00000378402;ENSP00000371638;ENSP00000323967,0,0,0,0
5190,TIAM1-EFNB1-EPHA2 complex,14988728,EFNB1;EPHA2;TIAM1,Ephrin-B1;Ephrin type-A receptor 2;Rho guanine nucleotide exchange factor TIAM1,GO:0022008;GO:0031175,neurogenesis;neuron projection development,biological_process;biological_process,ENSP00000204961;ENSP00000351209;ENSP00000286827,4,0,0,0
5193,TNFalpha-NFkappa B signaling complex,14743216,CHUK;IKBKG;KPNA3;NFKB1;NFKB2;NFKBIA;NFKBIB;NFKBIE;REL;RELA;RELB;TNIP2,Inhibitor of nuclear factor kappa-B kinase subunit alpha;NF-kappa-B essential modulator;Importin subunit alpha-4;Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p100 subunit;NF-kappa-B inhibitor alpha;NF-kappa-B inhibitor beta;NF-kappa-B inhibitor epsilon;Proto-oncogene c-Rel;Transcription factor p65;Transcription factor RelB;TNFAIP3-interacting protein 2,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000359424;ENSP00000483825;ENSP00000261667;ENSP00000226574;ENSP00000358983;ENSP00000216797;ENSP00000312988;ENSP00000275015;ENSP00000295025;ENSP00000384273;ENSP00000221452;ENSP00000321203,0,0,0,0
5194,"TNF-alpha/NF-kappa B signaling complex (SEC16A, CHUK, IKBKB, NFKB2, REL, IKBKG, MAP3K14, RELA, FBXW7, USP2)",14743216,CHUK;FBXW7;IKBKB;IKBKG;MAP3K14;NFKB2;REL;RELA;SEC16A;USP2,Inhibitor of nuclear factor kappa-B kinase subunit alpha;F-box/WD repeat-containing protein 7;Inhibitor of nuclear factor kappa-B kinase subunit beta;NF-kappa-B essential modulator;Mitogen-activated protein kinase kinase kinase 14;Nuclear factor NF-kappa-B p100 subunit;Proto-oncogene c-Rel;Transcription factor p65;Protein transport protein Sec16A;Ubiquitin carboxyl-terminal hydrolase 2,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000359424;ENSP00000474725;ENSP00000430684;ENSP00000483825;ENSP00000482657;ENSP00000358983;ENSP00000295025;ENSP00000384273;ENSP00000325827;ENSP00000260187,0,0,0,0
5196,"TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1)",14743216,ANKRD28;BTRC;CHUK;CUL1;IKBKE;NFKB2;PPP6C;PPP6R1;PPP6R2;REL;RELA;SKP1,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A;F-box/WD repeat-containing protein 1A;Inhibitor of nuclear factor kappa-B kinase subunit alpha;Cullin-1;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;Nuclear factor NF-kappa-B p100 subunit;Serine/threonine-protein phosphatase 6 catalytic subunit;Serine/threonine-protein phosphatase 6 regulatory subunit 1;Serine/threonine-protein phosphatase 6 regulatory subunit 2;Proto-oncogene c-Rel;Transcription factor p65;S-phase kinase-associated protein 1,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000382379;ENSP00000359206;ENSP00000359424;ENSP00000326804;ENSP00000464030;ENSP00000358983;ENSP00000392147;ENSP00000414202;ENSP00000478417;ENSP00000295025;ENSP00000384273;ENSP00000231487,0,0,0,0
5198,CREBBP-NCOA1-RARA-RXRA complex,8616895,CREBBP;NCOA1;RARA;RXRA,CREB-binding protein;Nuclear receptor coactivator 1;Retinoic acid receptor alpha;Retinoic acid receptor RXR-alpha,GO:0005634;GO:0023052;GO:0032870;GO:0045893,nucleus;signaling;cellular response to hormone stimulus;positive regulation of DNA-templated transcription,cellular_component;biological_process;biological_process;biological_process,ENSP00000262367;ENSP00000385216;ENSP00000254066;ENSP00000419692,7,7,0,7
5209,Ubiquilin-proteasome complex,10983987,PSMA1;PSMA2;PSMA6;UBE3A;UBQLN1;UBQLN2,Proteasome subunit alpha type-1;Proteasome subunit alpha type-2;Proteasome subunit alpha type-6;Ubiquitin-protein ligase E3A;Ubiquilin-1;Ubiquilin-2,GO:0006511;GO:0043161,ubiquitin-dependent protein catabolic process;proteasome-mediated ubiquitin-dependent protein catabolic process,biological_process;biological_process,ENSP00000414359;ENSP00000223321;ENSP00000261479;ENSP00000497594;ENSP00000365576;ENSP00000345195,7,7,0,0
5212,Kinase maturation complex 2,14743216,AZI2;CDC37;HSP90AA1;HSP90AB1;TANK;TBK1;TBKBP1;TRAF2,5-azacytidine-induced protein 2;Hsp90 co-chaperone Cdc37;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;TRAF family member-associated NF-kappa-B activator;Serine/threonine-protein kinase TBK1;TANK-binding kinase 1-binding protein 1;TNF receptor-associated factor 2,GO:0035556,intracellular signal transduction,biological_process,ENSP00000419371;ENSP00000222005;ENSP00000335153;ENSP00000360609;ENSP00000259075;ENSP00000329967;ENSP00000354777;ENSP00000247668,0,0,0,0
5226,LAMTOR2-LAMTOR3-MAPK1 complex,11266467,LAMTOR2;LAMTOR3;MAPK1,Ragulator complex protein LAMTOR2;Ragulator complex protein LAMTOR3;Mitogen-activated protein kinase 1,GO:0000165;GO:0005770;GO:0031434,MAPK cascade;late endosome;mitogen-activated protein kinase kinase binding,biological_process;cellular_component;molecular_function,ENSP00000357288;ENSP00000424183;ENSP00000215832,1,1,0,0
5232,TNFalpha-NFkappa B signaling complex,14743216,CHUK;DDX3X;GLG1;GTF2I;IKBKG;MAP3K8;NFKB1;NFKB2;NFKBIA;NFKBIB;REL;RELA;RELB;RPL30;RPL6;RPS13;TNIP2,Inhibitor of nuclear factor kappa-B kinase subunit alpha;ATP-dependent RNA helicase DDX3X;Golgi apparatus protein 1;General transcription factor II-I;NF-kappa-B essential modulator;Mitogen-activated protein kinase kinase kinase 8;Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p100 subunit;NF-kappa-B inhibitor alpha;NF-kappa-B inhibitor beta;Proto-oncogene c-Rel;Transcription factor p65;Transcription factor RelB;Large ribosomal subunit protein eL30;Large ribosomal subunit protein eL6;Small ribosomal subunit protein uS15;TNFAIP3-interacting protein 2,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000359424;ENSP00000494040;ENSP00000205061;ENSP00000460070;ENSP00000483825;ENSP00000263056;ENSP00000226574;ENSP00000358983;ENSP00000216797;ENSP00000312988;ENSP00000295025;ENSP00000384273;ENSP00000221452;ENSP00000428085;ENSP00000403172;ENSP00000435777;ENSP00000321203,0,0,0,0
5243,XRCC1-LIG3-PNK-TDP1 complex,15744309,LIG3;PNKP;TDP1;XRCC1,DNA ligase 3;Bifunctional polynucleotide phosphatase/kinase;Tyrosyl-DNA phosphodiesterase 1;DNA repair protein XRCC1,GO:0006281,DNA repair,biological_process,ENSP00000367787;ENSP00000323511;ENSP00000337353;ENSP00000262887,0,0,0,0
5260,CTNNB1-EP300-HADAC6-SUMO1-TCF4 complex,15782138,CTNNB1;EP300;HDAC6;SUMO1;TCF4,Catenin beta-1;Histone acetyltransferase p300;Histone deacetylase 6;Small ubiquitin-related modifier 1;Transcription factor 4,GO:0006351,DNA-templated transcription,biological_process,ENSP00000495360;ENSP00000263253;ENSP00000365804;ENSP00000376077;ENSP00000381382,0,0,0,0
5261,CTNNB1-EP300-TCF4 complex,15782138,CTNNB1;EP300;TCF4,Catenin beta-1;Histone acetyltransferase p300;Transcription factor 4,GO:0006351,DNA-templated transcription,biological_process,ENSP00000495360;ENSP00000263253;ENSP00000381382,30,30,0,0
5264,CTNNB1-CREBBP-TCF4 complex,15782138,CREBBP;CTNNB1;TCF4,CREB-binding protein;Catenin beta-1;Transcription factor 4,GO:0006351,DNA-templated transcription,biological_process,ENSP00000262367;ENSP00000495360;ENSP00000381382,42,42,0,0
5266,TNF-alpha/NF-kappa B signaling complex 6,14743216,CDC37;CHUK;FBL;HSP90AA1;HSP90AB1;IKBKB;IKBKG;MAP3K14;RPL30;RPL4;RPL6;RPL8;RPS11;RPS13,Hsp90 co-chaperone Cdc37;Inhibitor of nuclear factor kappa-B kinase subunit alpha;rRNA 2'-O-methyltransferase fibrillarin;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Inhibitor of nuclear factor kappa-B kinase subunit beta;NF-kappa-B essential modulator;Mitogen-activated protein kinase kinase kinase 14;Large ribosomal subunit protein eL30;Large ribosomal subunit protein uL4;Large ribosomal subunit protein eL6;Large ribosomal subunit protein uL2;Small ribosomal subunit protein uS17;Small ribosomal subunit protein uS15,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000222005;ENSP00000359424;ENSP00000221801;ENSP00000335153;ENSP00000360609;ENSP00000430684;ENSP00000483825;ENSP00000482657;ENSP00000428085;ENSP00000311430;ENSP00000403172;ENSP00000262584;ENSP00000270625;ENSP00000435777,0,0,0,0
5268,TNF-alpha/NF-kappa B signaling complex 7,14743216,CDC37;FKBP5;HSP90AA1;HSP90AB1;MAP3K7;TAB1;TAB2;TAB3,Hsp90 co-chaperone Cdc37;Peptidyl-prolyl cis-trans isomerase FKBP5;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Mitogen-activated protein kinase kinase kinase 7;TGF-beta-activated kinase 1 and MAP3K7-binding protein 1;TGF-beta-activated kinase 1 and MAP3K7-binding protein 2;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000222005;ENSP00000444810;ENSP00000335153;ENSP00000360609;ENSP00000358335;ENSP00000216160;ENSP00000356426;ENSP00000368215,0,0,0,0
5269,TNF-alpha/NF-kappa B signaling complex 8,14743216,CDC37;FKBP5;HSP90AA1;HSP90AB1;IKBKE;KTN1,Hsp90 co-chaperone Cdc37;Peptidyl-prolyl cis-trans isomerase FKBP5;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;Kinectin,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000222005;ENSP00000444810;ENSP00000335153;ENSP00000360609;ENSP00000464030;ENSP00000378725,0,0,0,0
5285,TNF-alpha/NF-kappa B signaling complex 9,14743216,CDC37;CHUK;FKBP5;HSP90AB1;NFKBIB,Hsp90 co-chaperone Cdc37;Inhibitor of nuclear factor kappa-B kinase subunit alpha;Peptidyl-prolyl cis-trans isomerase FKBP5;Heat shock protein HSP 90-beta;NF-kappa-B inhibitor beta,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000222005;ENSP00000359424;ENSP00000444810;ENSP00000360609;ENSP00000312988,0,0,0,0
5286,TNF-alpha/NF-kappa B signaling complex 10,14743216,ATG16L1;CCAR1;CDC37;CHUK;HSP90AA1;HSP90AB1;IKBKG;NFKBIB;TBK1;TXLNA,Autophagy-related protein 16-1;Cell division cycle and apoptosis regulator protein 1;Hsp90 co-chaperone Cdc37;Inhibitor of nuclear factor kappa-B kinase subunit alpha;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;NF-kappa-B essential modulator;NF-kappa-B inhibitor beta;Serine/threonine-protein kinase TBK1;Alpha-taxilin,GO:0005125;GO:0007249,cytokine activity;canonical NF-kappaB signal transduction,molecular_function;biological_process,ENSP00000375873;ENSP00000265872;ENSP00000222005;ENSP00000359424;ENSP00000335153;ENSP00000360609;ENSP00000483825;ENSP00000312988;ENSP00000329967;ENSP00000362711,0,0,0,0
5423,HSP70-BAG5-PARK2 complex,15603737,BAG5;HSPA1A;HSPA4;PRKN,BAG family molecular chaperone regulator 5;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 4;E3 ubiquitin-protein ligase parkin,GO:0006457;GO:0030234;GO:0050790;GO:0050821,protein folding;enzyme regulator activity;regulation of catalytic activity;protein stabilization,biological_process;molecular_function;biological_process;biological_process,ENSP00000338814;ENSP00000364802;ENSP00000302961;ENSP00000355865,0,0,0,0
5518,BMI1-HPH1-HPH2 complex,9121482,BMI1;PHC1;PHC2,Polycomb complex protein BMI-1;Polyhomeotic-like protein 1;Polyhomeotic-like protein 2,GO:0003677;GO:0005634;GO:0032774;GO:0045892,DNA binding;nucleus;RNA biosynthetic process;negative regulation of DNA-templated transcription,molecular_function;cellular_component;biological_process;biological_process,ENSP00000473391;ENSP00000437659;ENSP00000257118,0,0,0,0
5526,BCL2-CALM1-FKBP38 complex,15990872,BCL2;CALM1;FKBP8,Apoptosis regulator Bcl-2;Calmodulin-1;Peptidyl-prolyl cis-trans isomerase FKBP8,GO:0005509;GO:0006915;GO:0030234;GO:0043067;GO:0050790,calcium ion binding;apoptotic process;enzyme regulator activity;regulation of programmed cell death;regulation of catalytic activity,molecular_function;biological_process;molecular_function;biological_process;biological_process,ENSP00000381185;ENSP00000499717;ENSP00000471700,0,0,0,0
5579,CNTF-CNTFR-IL6ST-LIFR complex,8385113,CNTF;CNTFR;IL6ST;LIFR,Ciliary neurotrophic factor;Ciliary neurotrophic factor receptor subunit alpha;Interleukin-6 receptor subunit beta;Leukemia inhibitory factor receptor,GO:0019221;GO:0070120,cytokine-mediated signaling pathway;ciliary neurotrophic factor-mediated signaling pathway,biological_process;biological_process,ENSP00000355370;ENSP00000368265;ENSP00000370698;ENSP00000398368,0,0,0,0
5582,IL6ST-LIF-LIFR complex,8385113,IL6ST;LIF;LIFR,Interleukin-6 receptor subunit beta;Leukemia inhibitory factor;Leukemia inhibitory factor receptor,GO:0019221;GO:0048861,cytokine-mediated signaling pathway;leukemia inhibitory factor signaling pathway,biological_process;biological_process,ENSP00000370698;ENSP00000249075;ENSP00000398368,1,1,0,0
5641,DLG4-FYN-GRIN2A complex,9892651,DLG4;FYN;GRIN2A,"Disks large homolog 4;Tyrosine-protein kinase Fyn;Glutamate receptor ionotropic, NMDA 2A",GO:0005886;GO:0023052,plasma membrane;signaling,cellular_component;biological_process,ENSP00000497806;ENSP00000346671;ENSP00000332549,35,35,35,0
5646,FARP2-NRP1-PlexinA1 complex,16286926,FARP2;NRP1;PLXNA1,"FERM, ARHGEF and pleckstrin domain-containing protein 2;Neuropilin-1;Plexin-A1",GO:0007399;GO:0023052,nervous system development;signaling,biological_process;biological_process,ENSP00000264042;ENSP00000265371;ENSP00000377061,0,0,0,0
5647,FARP2-NRP1-PlexinA2 complex,16286926,FARP2;NRP1;PLXNA2,"FERM, ARHGEF and pleckstrin domain-containing protein 2;Neuropilin-1;Plexin-A2",GO:0007399;GO:0023052,nervous system development;signaling,biological_process;biological_process,ENSP00000264042;ENSP00000265371;ENSP00000356000,0,0,0,0
5648,FARP2-NRP1-PlexinA3 complex,16286926,FARP2;NRP1;PLXNA3,"FERM, ARHGEF and pleckstrin domain-containing protein 2;Neuropilin-1;Plexin-A3",GO:0007399;GO:0023052,nervous system development;signaling,biological_process;biological_process,ENSP00000264042;ENSP00000265371;ENSP00000358696,0,0,0,0
5649,FARP2-NRP1-PlexinA4 complex,16286926,FARP2;NRP1;PLXNA4,"FERM, ARHGEF and pleckstrin domain-containing protein 2;Neuropilin-1;Plexin-A4",GO:0007399;GO:0023052,nervous system development;signaling,biological_process;biological_process,ENSP00000264042;ENSP00000265371;ENSP00000352882,0,0,0,0
5689,SEMA6D-PlexinA1-NRP1 complex,14977921,NRP1;PLXNA1;SEMA6D,Neuropilin-1;Plexin-A1;Semaphorin-6D,GO:0003143;GO:0007399;GO:0007507;GO:0048738,embryonic heart tube morphogenesis;nervous system development;heart development;cardiac muscle tissue development,biological_process;biological_process;biological_process;biological_process,ENSP00000265371;ENSP00000377061;ENSP00000324857,0,0,0,0
5709,CBL-PTK2B-SORBS2 complex,15128873,CBL;PTK2B;SORBS2,E3 ubiquitin-protein ligase CBL;Protein-tyrosine kinase 2-beta;Sorbin and SH3 domain-containing protein 2,GO:0006605;GO:0006886;GO:0015031;GO:0030036;GO:0030182,protein targeting;intracellular protein transport;protein transport;actin cytoskeleton organization;neuron differentiation,biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000264033;ENSP00000380638;ENSP00000347852,60,60,0,0
5721,CIN85-CBL-SH3GL2 complex,11894095,CBL;SH3GL2;SH3KBP1,E3 ubiquitin-protein ligase CBL;Endophilin-A1;SH3 domain-containing kinase-binding protein 1,GO:0006897;GO:0006900;GO:0016050,endocytosis;vesicle budding from membrane;vesicle organization,biological_process;biological_process;biological_process,ENSP00000264033;ENSP00000369981;ENSP00000380921,66,66,0,0
5724,CIN85-SH3GL3-CBL complex,11894096,CBL;SH3GL3;SH3KBP1,E3 ubiquitin-protein ligase CBL;Endophilin-A3;SH3 domain-containing kinase-binding protein 1,GO:0006897;GO:0006900;GO:0007169;GO:0016050,endocytosis;vesicle budding from membrane;cell surface receptor protein tyrosine kinase signaling pathway;vesicle organization,biological_process;biological_process;biological_process;biological_process,ENSP00000264033;ENSP00000320092;ENSP00000380921,56,56,0,0
5746,NRP1-PLXNA1-SEMA3A complex,10520994,NRP1;PLXNA1;SEMA3A,Neuropilin-1;Plexin-A1;Semaphorin-3A,GO:0071526,semaphorin-plexin signaling pathway,biological_process,ENSP00000265371;ENSP00000377061;ENSP00000265362,0,0,0,0
5762,"CRMP-MICAL-PlexinA1 complex, induced by SEMA3A",18305261,CRMP1;MICAL1;PLXNA1,Dihydropyrimidinase-related protein 1;[F-actin]-monooxygenase MICAL1;Plexin-A1,GO:0007399;GO:0023052;GO:0031175,nervous system development;signaling;neuron projection development,biological_process;biological_process;biological_process,ENSP00000321606;ENSP00000486901;ENSP00000377061,22,0,0,22
5772,CDH5-CTNNB1-KDR-TJP1 complex,18662404,CDH5;CTNNB1;KDR;TJP1,Cadherin-5;Catenin beta-1;Vascular endothelial growth factor receptor 2;Tight junction protein ZO-1,GO:0001525;GO:0001568;GO:0001944;GO:0007043;GO:0007169;GO:0035924;GO:0038085;GO:0048010,angiogenesis;blood vessel development;vasculature development;cell-cell junction assembly;cell surface receptor protein tyrosine kinase signaling pathway;cellular response to vascular endothelial growth factor stimulus;vascular endothelial growth factor binding;vascular endothelial growth factor receptor signaling pathway,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;molecular_function;biological_process,ENSP00000497290;ENSP00000495360;ENSP00000263923;ENSP00000348416,0,0,0,0
5805,KEAP1-NRF2-PGAM5 complex,18387606,KEAP1;NFE2L2;PGAM5,"Kelch-like ECH-associated protein 1;Nuclear factor erythroid 2-related factor 2;Serine/threonine-protein phosphatase PGAM5, mitochondrial",GO:0000302;GO:0005741;GO:0006355;GO:2001141,response to reactive oxygen species;mitochondrial outer membrane;regulation of DNA-templated transcription;regulation of RNA biosynthetic process,biological_process;cellular_component;biological_process;biological_process,ENSP00000377245;ENSP00000380252;ENSP00000438465,0,0,0,0
5809,"GABA-A receptor (GABRA1, GABRB2, GABRG2)",11992121,GABRA1;GABRB2;GABRG2,Gamma-aminobutyric acid receptor subunit alpha-1;Gamma-aminobutyric acid receptor subunit beta-2;Gamma-aminobutyric acid receptor subunit gamma-2,GO:0005216;GO:0006821,monoatomic ion channel activity;chloride transport,molecular_function;biological_process,ENSP00000393097;ENSP00000274547;ENSP00000410732,133,133,133,0
5832,PINK1-RHOT2-TRAK1 complex,19152501,PINK1;RHOT2;TRAK1,"Serine/threonine-protein kinase PINK1, mitochondrial;Mitochondrial Rho GTPase 2;Trafficking kinesin-binding protein 1",GO:0005741;GO:0016192,mitochondrial outer membrane;vesicle-mediated transport,cellular_component;biological_process,ENSP00000364204;ENSP00000321971;ENSP00000328998,0,0,0,0
5837,PPD complex,19229105,PARK7;PINK1;PRKN,"Parkinson disease protein 7;Serine/threonine-protein kinase PINK1, mitochondrial;E3 ubiquitin-protein ligase parkin",GO:0005737;GO:0006511;GO:0043161,cytoplasm;ubiquitin-dependent protein catabolic process;proteasome-mediated ubiquitin-dependent protein catabolic process,cellular_component;biological_process;biological_process,ENSP00000340278;ENSP00000364204;ENSP00000355865,0,0,0,0
5849,CDC37-HSP90AB1-LRRK2 complex,16321986,CDC37;HSP90AB1;LRRK2,Hsp90 co-chaperone Cdc37;Heat shock protein HSP 90-beta;Leucine-rich repeat serine/threonine-protein kinase 2,GO:0035556;GO:0045859,intracellular signal transduction;regulation of protein kinase activity,biological_process;biological_process,ENSP00000222005;ENSP00000360609;ENSP00000298910,22,22,0,22
5870,APBB1-TSHZ3-HDAC1 complex,19343227,APBB1;HDAC1;TSHZ3,Amyloid beta precursor protein binding family B member 1;Histone deacetylase 1;Teashirt homolog 3,GO:0005634;GO:0045892,nucleus;negative regulation of DNA-templated transcription,cellular_component;biological_process,ENSP00000477213;ENSP00000362649;ENSP00000240587,15,15,0,0
5975,"Gamma-secretase complex (APH1A, NCSTN, PSENEN, PSEN1, TMP21)",16641999,APH1A;NCSTN;PSEN1;PSENEN;TMED10,Gamma-secretase subunit APH-1A;Nicastrin;Presenilin-1;Gamma-secretase subunit PEN-2;Transmembrane emp24 domain-containing protein 10,GO:0005794;GO:0005886;GO:0007219;GO:0016485;GO:0051090;GO:0070765,Golgi apparatus;plasma membrane;Notch signaling pathway;protein processing;regulation of DNA-binding transcription factor activity;gamma-secretase complex,cellular_component;cellular_component;biological_process;biological_process;biological_process;cellular_component,ENSP00000358105;ENSP00000294785;ENSP00000326366;ENSP00000468411;ENSP00000303145,0,0,0,0
5980,HSP90AB1-LRRK2-STUB1 complex,19196961,HSP90AB1;LRRK2;STUB1,Heat shock protein HSP 90-beta;Leucine-rich repeat serine/threonine-protein kinase 2;E3 ubiquitin-protein ligase CHIP,GO:0043161;GO:2000058,proteasome-mediated ubiquitin-dependent protein catabolic process;regulation of ubiquitin-dependent protein catabolic process,biological_process;biological_process,ENSP00000360609;ENSP00000298910;ENSP00000219548,34,34,0,34
5991,LRRK2-FADD-CASP8 complex,19176810,CASP8;FADD;LRRK2,Caspase-8;FAS-associated death domain protein;Leucine-rich repeat serine/threonine-protein kinase 2,GO:0006915,apoptotic process,biological_process,ENSP00000351273;ENSP00000301838;ENSP00000298910,2,2,0,2
6037,HSPA8-MAPT-STUB1-UBE2D2 complex,14612456,HSPA8;MAPT;STUB1;UBE2D2,Heat shock cognate 71 kDa protein;Microtubule-associated protein tau;E3 ubiquitin-protein ligase CHIP;Ubiquitin-conjugating enzyme E2 D2,GO:0006511;GO:0016567;GO:0031072;GO:0031625;GO:0043161;GO:0048156,ubiquitin-dependent protein catabolic process;protein ubiquitination;heat shock protein binding;ubiquitin protein ligase binding;proteasome-mediated ubiquitin-dependent protein catabolic process;tau protein binding,biological_process;biological_process;molecular_function;molecular_function;biological_process;molecular_function,ENSP00000437125;ENSP00000340820;ENSP00000219548;ENSP00000381717,12,12,0,0
6038,Dynein complex,17403682,DYNC1H1;DYNC1I1;DYNC1LI1;DYNLL1,"Cytoplasmic dynein 1 heavy chain 1;Cytoplasmic dynein 1 intermediate chain 1;Cytoplasmic dynein 1 light intermediate chain 1;Dynein light chain 1, cytoplasmic",GO:0030705,cytoskeleton-dependent intracellular transport,biological_process,ENSP00000348965;ENSP00000320130;ENSP00000273130;ENSP00000376297,0,0,0,0
6039,Dynein-dynactin complex,17403682,DCTN1;DYNC1H1;DYNC1I1;DYNC1LI1;DYNLL1,"Dynactin subunit 1;Cytoplasmic dynein 1 heavy chain 1;Cytoplasmic dynein 1 intermediate chain 1;Cytoplasmic dynein 1 light intermediate chain 1;Dynein light chain 1, cytoplasmic",GO:0030705,cytoskeleton-dependent intracellular transport,biological_process,ENSP00000354791;ENSP00000348965;ENSP00000320130;ENSP00000273130;ENSP00000376297,0,0,0,0
6043,DISC-FEZ1-F-actin complex,12874605,ACTG1;DISC1;FEZ1,"Actin, cytoplasmic 2;Disrupted in schizophrenia 1 protein;Fasciculation and elongation protein zeta-1",GO:0000902;GO:0016049,cell morphogenesis;cell growth,biological_process;biological_process,ENSP00000458162;ENSP00000403888;ENSP00000497070,0,0,0,0
6072,TRA2B1-SRSF9-SRSF6 complex,15695522,SRSF6;SRSF9;TRA2B,Serine/arginine-rich splicing factor 6;Serine/arginine-rich splicing factor 9;Transformer-2 protein homolog beta,GO:0043484;GO:0048024,"regulation of RNA splicing;regulation of mRNA splicing, via spliceosome",biological_process;biological_process,ENSP00000244020;ENSP00000229390;ENSP00000416959,0,0,0,0
6136,USP7-MAGEL2-TRIM27 complex,26365382,MAGEL2;TRIM27;USP7,MAGE-like protein 2;Zinc finger protein RFP;Ubiquitin carboxyl-terminal hydrolase 7,GO:0016197,endosomal transport,biological_process,ENSP00000497810;ENSP00000366404;ENSP00000343535,0,0,0,0
6163,BBSome,25964651,BBIP1;BBS1;BBS2;BBS4;BBS5;BBS7;BBS9;TTC8,BBSome-interacting protein 1;BBSome complex member BBS1;BBSome complex member BBS2;BBSome complex member BBS4;BBSome complex member BBS5;BBSome complex member BBS7;Protein PTHB1;Tetratricopeptide repeat protein 8,GO:0005929;GO:0007601;GO:0042073;GO:0044782;GO:0060170;GO:0060271;GO:0097733,cilium;visual perception;intraciliary transport;cilium organization;ciliary membrane;cilium assembly;photoreceptor cell cilium,cellular_component;biological_process;biological_process;biological_process;cellular_component;biological_process;cellular_component,ENSP00000433157;ENSP00000317469;ENSP00000245157;ENSP00000268057;ENSP00000295240;ENSP00000264499;ENSP00000242067;ENSP00000482306,0,0,0,0
6167,Exocyst complex,25964651,EXOC1;EXOC2;EXOC3;EXOC4;EXOC5;EXOC6;EXOC7;EXOC8,Exocyst complex component 1;Exocyst complex component 2;Exocyst complex component 3;Exocyst complex component 4;Exocyst complex component 5;Exocyst complex component 6;Exocyst complex component 7;Exocyst complex component 8,GO:0006887;GO:0060271;GO:0099022,exocytosis;cilium assembly;vesicle tethering,biological_process;biological_process;biological_process,ENSP00000370695;ENSP00000230449;ENSP00000425587;ENSP00000253861;ENSP00000484855;ENSP00000260762;ENSP00000334100;ENSP00000355605,0,0,0,0
6175,Caspase-10-SUMO-FADD/Drp1 complex,27799292,CASP10;DNM1L;FADD,Caspase-10;Dynamin-1-like protein;FAS-associated death domain protein,GO:0005739;GO:0070266,mitochondrion;necroptotic process,cellular_component;biological_process,ENSP00000286186;ENSP00000449089;ENSP00000301838,0,0,0,0
6186,ArPIKfyve-Sac3-Sph1 complex,26405034,FIG4;PIKFYVE;SNCAIP,Polyphosphoinositide phosphatase;1-phosphatidylinositol 3-phosphate 5-kinase;Synphilin-1,GO:0050821,protein stabilization,biological_process,ENSP00000230124;ENSP00000264380;ENSP00000261367,28,0,0,0
6192,CHDH-SQSTM1-MAP1LC3 complex,25483962,CHDH;MAP1LC3A;SQSTM1,"Choline dehydrogenase, mitochondrial;Microtubule-associated proteins 1A/1B light chain 3A;Sequestosome-1",GO:0061734,type 2 mitophagy,biological_process,ENSP00000319851;ENSP00000363970;ENSP00000374455,0,0,0,0
6195,Stargazin-AP-2-AP-3a complex,24217640,AP2A1;AP3D1;CACNG2,AP-2 complex subunit alpha-1;AP-3 complex subunit delta-1;Voltage-dependent calcium channel gamma-2 subunit,GO:2000311,regulation of AMPA receptor activity,biological_process,ENSP00000351926;ENSP00000495274;ENSP00000300105,0,0,0,0
6196,Stargazin-Glu1-mu2 complex,24217640,AP2M1;CACNG2;GRIA1,AP-2 complex subunit mu;Voltage-dependent calcium channel gamma-2 subunit;Glutamate receptor 1,GO:2000311,regulation of AMPA receptor activity,biological_process,ENSP00000403362;ENSP00000300105;ENSP00000428994,0,0,0,0
6197,Stargazin-Glu1-mu3 complex,24217640,AP3M2;CACNG2;GRIA1,AP-3 complex subunit mu-2;Voltage-dependent calcium channel gamma-2 subunit;Glutamate receptor 1,GO:2000311,regulation of AMPA receptor activity,biological_process,ENSP00000428787;ENSP00000300105;ENSP00000428994,0,0,0,0
6198,Stargazin-Glu2A-mu2 complex,24217640,AP2M1;CACNG2;GRIA2,AP-2 complex subunit mu;Voltage-dependent calcium channel gamma-2 subunit;Glutamate receptor 2,GO:2000311,regulation of AMPA receptor activity,biological_process,ENSP00000403362;ENSP00000300105;ENSP00000296526,30,30,30,0
6199,Stargazin-Glu2A-mu3 complex,24217640,AP3M2;CACNG2;GRIA2,AP-3 complex subunit mu-2;Voltage-dependent calcium channel gamma-2 subunit;Glutamate receptor 2,GO:2000311,regulation of AMPA receptor activity,biological_process,ENSP00000428787;ENSP00000300105;ENSP00000296526,0,0,0,0
6209,GNAI1-GNB1-GNG2-MTNR1A-RGS20 complex,20859254,GNAI1;GNB1;GNG2;MTNR1A;RGS20,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Melatonin receptor type 1A;Regulator of G-protein signaling 20,GO:0007186;GO:1901379,G protein-coupled receptor signaling pathway;regulation of potassium ion transmembrane transport,biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000334448;ENSP00000302811;ENSP00000297313,0,0,0,0
6211,MTNR1A-MTNR1B-RGS20 complex,20859254,MTNR1A;MTNR1B;RGS20,Melatonin receptor type 1A;Melatonin receptor type 1B;Regulator of G-protein signaling 20,GO:0007186,G protein-coupled receptor signaling pathway,biological_process,ENSP00000302811;ENSP00000257068;ENSP00000297313,0,0,0,0
6215,GATOR1 complex,23723238,DEPDC5;NPRL2;NPRL3,GATOR1 complex protein DEPDC5;GATOR1 complex protein NPRL2;GATOR1 complex protein NPRL3,GO:0005096;GO:1903832;GO:1904262,GTPase activator activity;regulation of cellular response to amino acid starvation;negative regulation of TORC1 signaling,molecular_function;biological_process;biological_process,ENSP00000498382;ENSP00000232501;ENSP00000483814,0,0,0,0
6217,GATOR complex,23723238,DEPDC5;MIOS;NPRL2;NPRL3;SEC13;SEH1L;WDR24;WDR59,GATOR1 complex protein DEPDC5;GATOR2 complex protein MIOS;GATOR1 complex protein NPRL2;GATOR1 complex protein NPRL3;Protein SEC13 homolog;Nucleoporin SEH1;GATOR2 complex protein WDR24;GATOR2 complex protein WDR59,GO:1903432;GO:1903832,regulation of TORC1 signaling;regulation of cellular response to amino acid starvation,biological_process;biological_process,ENSP00000498382;ENSP00000339881;ENSP00000232501;ENSP00000483814;ENSP00000373312;ENSP00000382779;ENSP00000293883;ENSP00000262144,0,0,0,0
6223,CCM2-ICAP1-KRIT1 complex,16037064,CCM2;ITGB1BP1;KRIT1,Cerebral cavernous malformations 2 protein;Integrin beta-1-binding protein 1;Krev interaction trapped protein 1,GO:0007155,cell adhesion,biological_process,ENSP00000370503;ENSP00000353850;ENSP00000378015,0,0,0,0
6224,CCM2-KRIT1-MEKK3 complex,16037064,CCM2;KRIT1;MAP3K3,Cerebral cavernous malformations 2 protein;Krev interaction trapped protein 1;Mitogen-activated protein kinase kinase kinase 3,GO:1900744,regulation of p38MAPK cascade,biological_process,ENSP00000370503;ENSP00000378015;ENSP00000354927,1,1,0,0
6242,MAPT-SGK1-YWHAQ complex,15650334,MAPT;SGK1;YWHAQ,Microtubule-associated protein tau;Serine/threonine-protein kinase Sgk1;14-3-3 protein theta,GO:0005875;GO:0048156;GO:0071889;GO:0120283,microtubule associated complex;tau protein binding;14-3-3 protein binding;protein serine/threonine kinase binding,cellular_component;molecular_function;molecular_function;molecular_function,ENSP00000340820;ENSP00000356832;ENSP00000371267,53,53,0,0
6257,ANKS6-NEK8-INVS-NPHP3 complex,23793029,ANKS6;INVS;NEK8;NPHP3,Ankyrin repeat and SAM domain-containing protein 6;Inversin;Serine/threonine-protein kinase Nek8;Nephrocystin-3,GO:0001822;GO:0005929,kidney development;cilium,biological_process;cellular_component,ENSP00000297837;ENSP00000262457;ENSP00000268766;ENSP00000338766,0,0,0,0
6259,USH2 complex,25406310,ADGRV1;PDZD7;USH2A;WHRN,Adhesion G-protein coupled receptor V1;PDZ domain-containing protein 7;Usherin;Whirlin,GO:0007186;GO:0007601,G protein-coupled receptor signaling pathway;visual perception,biological_process;biological_process,ENSP00000384582;ENSP00000480489;ENSP00000305941;ENSP00000354623,0,0,0,0
6269,DLL1-CTNNB1-CDH2 complex,15908431,CDH2;CTNNB1;DLL1,Cadherin-2;Catenin beta-1;Delta-like protein 1,GO:0005912;GO:0071896,adherens junction;protein localization to adherens junction,cellular_component;biological_process,ENSP00000269141;ENSP00000495360;ENSP00000355718,0,0,0,0
6293,DDN-MAGI2-SH3KBP1 complex,16751601,DDN;MAGI2;SH3KBP1,"Dendrin;Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2;SH3 domain-containing kinase-binding protein 1",GO:0043197,dendritic spine,cellular_component,ENSP00000390590;ENSP00000346151;ENSP00000380921,0,0,0,0
6321,DLG4-DLGAP1-SHANK3 complex,10527873,DLG4;DLGAP1;SHANK3,Disks large homolog 4;Disks large-associated protein 1;SH3 and multiple ankyrin repeat domains protein 3,,,,ENSP00000497806;ENSP00000316377;ENSP00000489407,33,33,33,0
6323,Cardinal-NLRP3 inflammasome,15030775,CARD8;CASP1;NLRP3;PYCARD,"Caspase recruitment domain-containing protein 8;Caspase-1;NACHT, LRR and PYD domains-containing protein 3;Apoptosis-associated speck-like protein containing a CARD",GO:0002221;GO:0006952;GO:0032692;GO:0032731;GO:0045087;GO:0050727;GO:0061702;GO:0072559;GO:0140447,pattern recognition receptor signaling pathway;defense response;negative regulation of interleukin-1 production;positive regulation of interleukin-1 beta production;innate immune response;regulation of inflammatory response;canonical inflammasome complex;NLRP3 inflammasome complex;cytokine precursor processing,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;cellular_component;cellular_component;biological_process,ENSP00000499211;ENSP00000433138;ENSP00000337383;ENSP00000247470,11,11,0,0
6332,"Elongator complex (ELP1, ELP2, ELP3, ELP4, ELP5, ELP6)",22854966,ELP1;ELP2;ELP3;ELP4;ELP5;ELP6,Elongator complex protein 1;Elongator complex protein 2;Elongator complex protein 3;Elongator complex protein 4;Elongator complex protein 5;Elongator complex protein 6,GO:0006357,regulation of transcription by RNA polymerase II,biological_process,ENSP00000363779;ENSP00000414851;ENSP00000256398;ENSP00000379267;ENSP00000379869;ENSP00000296149,0,0,0,0
6344,"TNFR1 signaling complex, native",20005846,BIRC3;CHUK;IKBKB;IKBKG;MAP3K7;RBCK1;RIPK1;RNF31;TAB1;TAB2;TNF;TNFRSF1A;TNIP1;TRADD;TRAF2,Baculoviral IAP repeat-containing protein 3;Inhibitor of nuclear factor kappa-B kinase subunit alpha;Inhibitor of nuclear factor kappa-B kinase subunit beta;NF-kappa-B essential modulator;Mitogen-activated protein kinase kinase kinase 7;RanBP-type and C3HC4-type zinc finger-containing protein 1;Receptor-interacting serine/threonine-protein kinase 1;E3 ubiquitin-protein ligase RNF31;TGF-beta-activated kinase 1 and MAP3K7-binding protein 1;TGF-beta-activated kinase 1 and MAP3K7-binding protein 2;Tumor necrosis factor;Tumor necrosis factor receptor superfamily member 1A;TNFAIP3-interacting protein 1;Tumor necrosis factor receptor type 1-associated DEATH domain protein;TNF receptor-associated factor 2,GO:0002947;GO:0005031;GO:0006954;GO:0007250;GO:0010803;GO:0016567;GO:0033209;GO:0034612;GO:0042981;GO:0046328;GO:0051092,tumor necrosis factor receptor superfamily complex;tumor necrosis factor receptor activity;inflammatory response;activation of NF-kappaB-inducing kinase activity;regulation of tumor necrosis factor-mediated signaling pathway;protein ubiquitination;tumor necrosis factor-mediated signaling pathway;response to tumor necrosis factor;regulation of apoptotic process;regulation of JNK cascade;positive regulation of NF-kappaB transcription factor activity,cellular_component;molecular_function;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000263464;ENSP00000359424;ENSP00000430684;ENSP00000483825;ENSP00000358335;ENSP00000348632;ENSP00000259808;ENSP00000315112;ENSP00000216160;ENSP00000356426;ENSP00000398698;ENSP00000162749;ENSP00000317891;ENSP00000341268;ENSP00000247668,0,0,0,0
6352,FoxM1-Axin-GSK3beta complex,26912724,AXIN1;FOXM1;GSK3B,Axin-1;Forkhead box protein M1;Glycogen synthase kinase-3 beta,,,,ENSP00000262320;ENSP00000342307;ENSP00000324806,1,1,0,0
6374,Calcineurin-FKBP1A complex,8524402,FKBP1A;PPP3CA;PPP3R1,Peptidyl-prolyl cis-trans isomerase FKBP1A;Protein phosphatase 3 catalytic subunit alpha;Calcineurin subunit B type 1,GO:0005516;GO:0005955;GO:0016791;GO:0019722;GO:0042110,calmodulin binding;calcineurin complex;phosphatase activity;calcium-mediated signaling;T cell activation,molecular_function;cellular_component;molecular_function;biological_process;biological_process,ENSP00000383003;ENSP00000378323;ENSP00000234310,4,4,0,4
6388,CORVET complex,26463206,TGFBRAP1;VPS11;VPS16;VPS18;VPS33A;VPS8,Transforming growth factor-beta receptor-associated protein 1;Vacuolar protein sorting-associated protein 11 homolog;Vacuolar protein sorting-associated protein 16 homolog;Vacuolar protein sorting-associated protein 18 homolog;Vacuolar protein sorting-associated protein 33A;Vacuolar protein sorting-associated protein 8 homolog,GO:0033263;GO:0034058;GO:0099022,CORVET complex;endosomal vesicle fusion;vesicle tethering,cellular_component;biological_process;biological_process,ENSP00000377027;ENSP00000481126;ENSP00000369810;ENSP00000220509;ENSP00000267199;ENSP00000487164,0,0,0,0
6389,HOPS complex,26463206,VPS11;VPS16;VPS18;VPS33A;VPS39;VPS41,Vacuolar protein sorting-associated protein 11 homolog;Vacuolar protein sorting-associated protein 16 homolog;Vacuolar protein sorting-associated protein 18 homolog;Vacuolar protein sorting-associated protein 33A;Vam6/Vps39-like protein;Vacuolar protein sorting-associated protein 41 homolog,GO:0019048;GO:0034058;GO:0035542;GO:0051607;GO:0061909;GO:0099022,modulation by virus of host process;endosomal vesicle fusion;regulation of SNARE complex assembly;defense response to virus;autophagosome-lysosome fusion;vesicle tethering,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000481126;ENSP00000369810;ENSP00000220509;ENSP00000267199;ENSP00000335193;ENSP00000309457,0,0,0,0
6391,KCTD12-GNB1-GNG2 complex,24836506,GNB1;GNG2;KCTD12,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;BTB/POZ domain-containing protein KCTD12,GO:0002029,desensitization of G protein-coupled receptor signaling pathway,biological_process,ENSP00000367872;ENSP00000334448;ENSP00000366694,41,41,0,0
6392,KCTD8-GNB1-GNG2 complex,24836506,GNB1;GNG2;KCTD8,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;BTB/POZ domain-containing protein KCTD8,GO:0008277,regulation of G protein-coupled receptor signaling pathway,biological_process,ENSP00000367872;ENSP00000334448;ENSP00000353129,33,0,33,0
6393,KCTD16-GNB1-GNG2 complex,24836506,GNB1;GNG2;KCTD16,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;BTB/POZ domain-containing protein KCTD16,GO:0008277,regulation of G protein-coupled receptor signaling pathway,biological_process,ENSP00000367872;ENSP00000334448;ENSP00000426548,47,47,47,0
6416,dysbindin-Snapin-BLOS2 complex,22203680,BLOC1S2;DTNBP1;SNAPIN,Biogenesis of lysosome-related organelles complex 1 subunit 2;Dysbindin;SNARE-associated protein Snapin,,,,ENSP00000359398;ENSP00000341680;ENSP00000357674,0,0,0,0
6418,C1q complex,938474,C1QA;C1QB;C1QC,Complement C1q subcomponent subunit A;Complement C1q subcomponent subunit B;Complement C1q subcomponent subunit C,GO:0002376;GO:0006955;GO:0006956;GO:0006958;GO:0045087,"immune system process;immune response;complement activation;complement activation, classical pathway;innate immune response",biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000363773;ENSP00000313967;ENSP00000363770,6,6,6,0
6429,SPG3A-SPG4-SPG31 complex,20200447,ATL1;REEP1;SPAST,Atlastin-1;Receptor expression-enhancing protein 1;Spastin,GO:0007029;GO:0008017,endoplasmic reticulum organization;microtubule binding,biological_process;molecular_function,ENSP00000351155;ENSP00000392197;ENSP00000320885,0,0,0,0
6439,SCNN1B-SCNN1D-SCNN1G complex,16423824,SCNN1B;SCNN1D;SCNN1G,Amiloride-sensitive sodium channel subunit beta;Amiloride-sensitive sodium channel subunit delta;Amiloride-sensitive sodium channel subunit gamma,GO:0006814,sodium ion transport,biological_process,ENSP00000345751;ENSP00000368411;ENSP00000300061,0,0,0,0
6450,AR-EFCAB6-PARK7 complex,12612053,AR;EFCAB6;PARK7,Androgen receptor;EF-hand calcium-binding domain-containing protein 6;Parkinson disease protein 7,GO:0005634;GO:0006355;GO:0032870;GO:0033574;GO:0060765,nucleus;regulation of DNA-templated transcription;cellular response to hormone stimulus;response to testosterone;regulation of androgen receptor signaling pathway,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000363822;ENSP00000262726;ENSP00000340278,30,30,0,0
6463,GARP complex,20685960,VPS51;VPS52;VPS53;VPS54,Vacuolar protein sorting-associated protein 51 homolog;Vacuolar protein sorting-associated protein 52 homolog;Vacuolar protein sorting-associated protein 53 homolog;Vacuolar protein sorting-associated protein 54,GO:0000938;GO:0005802;GO:0042147,"GARP complex;trans-Golgi network;retrograde transport, endosome to Golgi",cellular_component;cellular_component;biological_process,ENSP00000279281;ENSP00000409952;ENSP00000401435;ENSP00000272322,0,0,0,0
6473,Mitochondrial calcium uniporter complex,24231807,MCU;MCUB;MICU1;MICU2;SMDT1,"Calcium uniporter protein, mitochondrial;Calcium uniporter regulatory subunit MCUb, mitochondrial;Calcium uptake protein 1, mitochondrial;Calcium uptake protein 2, mitochondrial;Essential MCU regulator, mitochondrial",GO:0005739;GO:0006851;GO:0051560,mitochondrion;mitochondrial calcium ion transmembrane transport;mitochondrial calcium ion homeostasis,cellular_component;biological_process;biological_process,ENSP00000362144;ENSP00000378145;ENSP00000493232;ENSP00000371811;ENSP00000327467,0,0,0,0
6476,erlin1/2-RNF170 complex,21610068,ERLIN1;ERLIN2;RNF170,Erlin-1;Erlin-2;E3 ubiquitin-protein ligase RNF170,GO:0001881;GO:0005789,receptor recycling;endoplasmic reticulum membrane,biological_process;cellular_component,ENSP00000410964;ENSP00000428112;ENSP00000445725,0,0,0,0
6481,WASH complex,20498093,WASHC1;WASHC2C;WASHC3;WASHC4;WASHC5,WASH complex subunit 1;WASH complex subunit 2C;WASH complex subunit 3;WASH complex subunit 4;WASH complex subunit 5,GO:0016197;GO:0099050,endosomal transport;vesicle scission,biological_process;biological_process,ENSP00000485627;ENSP00000485513;ENSP00000240079;ENSP00000484713;ENSP00000318016,0,0,0,0
6484,WASH-CAPZalpa/beta complex,20498093,CAPZA1;CAPZB;WASHC1;WASHC2C;WASHC3;WASHC4;WASHC5,F-actin-capping protein subunit alpha-1;F-actin-capping protein subunit beta;WASH complex subunit 1;WASH complex subunit 2C;WASH complex subunit 3;WASH complex subunit 4;WASH complex subunit 5,GO:0005769;GO:0016197;GO:0034314;GO:0051693;GO:0099050,early endosome;endosomal transport;Arp2/3 complex-mediated actin nucleation;actin filament capping;vesicle scission,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000263168;ENSP00000401010;ENSP00000485627;ENSP00000485513;ENSP00000240079;ENSP00000484713;ENSP00000318016,0,0,0,0
6517,SERCA2a-alphaKAP-CaM-CaMKII complex,19671701,ATP2A2;CALM1;CAMK2A;KPNA1,Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;Calmodulin-1;Calcium/calmodulin-dependent protein kinase type II subunit alpha;Importin subunit alpha-5,,,,ENSP00000440045;ENSP00000499717;ENSP00000500386;ENSP00000343701,0,0,0,0
6527,ADGRL3-FLRT3-UNC5B complex,26235030,ADGRL3;FLRT3;UNC5B,Adhesion G protein-coupled receptor L3;Leucine-rich repeat transmembrane protein FLRT3;Netrin receptor UNC5B,GO:0001764;GO:0007186;GO:0007416;GO:0098609,neuron migration;G protein-coupled receptor signaling pathway;synapse assembly;cell-cell adhesion,biological_process;biological_process;biological_process;biological_process,ENSP00000422533;ENSP00000339912;ENSP00000334329,0,0,0,0
6528,ADGRL3-FLRT3-UNC5D complex,26235030,ADGRL3;FLRT3;UNC5D,Adhesion G protein-coupled receptor L3;Leucine-rich repeat transmembrane protein FLRT3;Netrin receptor UNC5D,GO:0001764;GO:0007186;GO:0007416;GO:0098609,neuron migration;G protein-coupled receptor signaling pathway;synapse assembly;cell-cell adhesion,biological_process;biological_process;biological_process;biological_process,ENSP00000422533;ENSP00000339912;ENSP00000385143,0,0,0,0
6559,KIF5A-RAB11B-ZFYVE27 complex,21976701,KIF5A;RAB11B;ZFYVE27,Kinesin heavy chain isoform 5A;Ras-related protein Rab-11B;Protrudin,GO:0005783;GO:0016192;GO:0071787;GO:0071788,endoplasmic reticulum;vesicle-mediated transport;endoplasmic reticulum tubular network formation;endoplasmic reticulum tubular network maintenance,cellular_component;biological_process;biological_process;biological_process,ENSP00000408979;ENSP00000333547;ENSP00000409594,9,0,9,9
6585,Intraflagellar transport complex A,20889716,IFT122;IFT140;TTC21B;WDR19;WDR35,Intraflagellar transport protein 122 homolog;Intraflagellar transport protein 140 homolog;Tetratricopeptide repeat protein 21B;WD repeat-containing protein 19;WD repeat-containing protein 35,GO:0005929;GO:0007224;GO:0035721;GO:0042073;GO:0060271,cilium;smoothened signaling pathway;intraciliary retrograde transport;intraciliary transport;cilium assembly,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000296266;ENSP00000406012;ENSP00000243344;ENSP00000382717;ENSP00000314444,13,13,13,0
6602,AP5-SPG11-SPG15 complex,23825025,AP5B1;AP5M1;AP5S1;AP5Z1;SPG11;ZFYVE26,AP-5 complex subunit beta-1;AP-5 complex subunit mu-1;AP-5 complex subunit sigma-1;AP-5 complex subunit zeta-1;Spatacsin;Zinc finger FYVE domain-containing protein 26,GO:0005764;GO:0005768;GO:0005794;GO:0006605;GO:0006886;GO:0030133;GO:0044599,lysosome;endosome;Golgi apparatus;protein targeting;intracellular protein transport;transport vesicle;AP-5 adaptor complex,cellular_component;cellular_component;cellular_component;biological_process;biological_process;cellular_component;cellular_component,ENSP00000454303;ENSP00000261558;ENSP00000481750;ENSP00000497815;ENSP00000261866;ENSP00000251119,0,0,0,0
6616,CADM1-4.1B-MPP3 complex,25780926,CADM1;EPB41L3;MPP3,Cell adhesion molecule 1;Band 4.1-like protein 3;MAGUK p55 subfamily member 3,,,,ENSP00000329797;ENSP00000343158;ENSP00000381430,0,0,0,0
6626,AP5 adaptor complex,22022230,AP5B1;AP5M1;AP5S1;AP5Z1,AP-5 complex subunit beta-1;AP-5 complex subunit mu-1;AP-5 complex subunit sigma-1;AP-5 complex subunit zeta-1,GO:0005764;GO:0005768;GO:0005794;GO:0006605;GO:0006886;GO:0015031;GO:0030133;GO:0044599,lysosome;endosome;Golgi apparatus;protein targeting;intracellular protein transport;protein transport;transport vesicle;AP-5 adaptor complex,cellular_component;cellular_component;cellular_component;biological_process;biological_process;biological_process;cellular_component;cellular_component,ENSP00000454303;ENSP00000261558;ENSP00000481750;ENSP00000497815,0,0,0,0
6644,CCDC22-COMMD1-CUL2 complex,23563313,CCDC22;COMMD1;CUL2,Coiled-coil domain-containing protein 22;COMM domain-containing protein 1;Cullin-2,GO:0016567,protein ubiquitination,biological_process,ENSP00000365401;ENSP00000308236;ENSP00000414095,0,0,0,0
6645,CCC complex,25355947,CCDC22;CCDC93;COMMD1;COMMD10;COMMD2;COMMD3;COMMD4;COMMD5;COMMD6;COMMD7;COMMD8;COMMD9;VPS35L,Coiled-coil domain-containing protein 22;Coiled-coil domain-containing protein 93;COMM domain-containing protein 1;COMM domain-containing protein 10;COMM domain-containing protein 2;COMM domain-containing protein 3;COMM domain-containing protein 4;COMM domain-containing protein 5;COMM domain-containing protein 6;COMM domain-containing protein 7;COMM domain-containing protein 8;COMM domain-containing protein 9;VPS35 endosomal protein-sorting factor-like,GO:0005769;GO:0055070,early endosome;copper ion homeostasis,cellular_component;biological_process,ENSP00000365401;ENSP00000365477;ENSP00000308236;ENSP00000274458;ENSP00000419475;ENSP00000366032;ENSP00000267935;ENSP00000394331;ENSP00000348054;ENSP00000278980;ENSP00000370984;ENSP00000263401;ENSP00000251143,0,0,0,0
6658,CCDC22-COMMD8-CUL1 complex,23563313,CCDC22;COMMD8;CUL1,Coiled-coil domain-containing protein 22;COMM domain-containing protein 8;Cullin-1,GO:0008384;GO:0016567,IkappaB kinase activity;protein ubiquitination,molecular_function;biological_process,ENSP00000365401;ENSP00000370984;ENSP00000326804,0,0,0,0
6659,"Ubiquitin E3 ligase (CCDC22, COMMD8, CUL3)",23563313,CCDC22;COMMD8;CUL3,Coiled-coil domain-containing protein 22;COMM domain-containing protein 8;Cullin-3,GO:0016567;GO:0031461,protein ubiquitination;cullin-RING ubiquitin ligase complex,biological_process;cellular_component,ENSP00000365401;ENSP00000370984;ENSP00000264414,0,0,0,0
6671,PI4K2A-WASH complex,23676666,AP3B1;ARHGEF1;ARHGEF2;CAPZA1;CAPZB;CLTC;DNM2;DOCK7;FKBP15;NEDD4;PI4K2A;WASHC2A;WASHC4;WASHC5,AP-3 complex subunit beta-1;Rho guanine nucleotide exchange factor 1;Rho guanine nucleotide exchange factor 2;F-actin-capping protein subunit alpha-1;F-actin-capping protein subunit beta;Clathrin heavy chain 1;Dynamin-2;Dedicator of cytokinesis protein 7;FK506-binding protein 15;E3 ubiquitin-protein ligase NEDD4;Phosphatidylinositol 4-kinase type 2-alpha;WASH complex subunit 2A;WASH complex subunit 4;WASH complex subunit 5,GO:0005769;GO:0071203,early endosome;WASH complex,cellular_component;cellular_component,ENSP00000255194;ENSP00000337261;ENSP00000354837;ENSP00000263168;ENSP00000401010;ENSP00000479606;ENSP00000373905;ENSP00000251157;ENSP00000416158;ENSP00000424827;ENSP00000359665;ENSP00000282633;ENSP00000484713;ENSP00000318016,0,0,0,0
6741,INPP5E-PDE6D-RPGR complex,28172980,INPP5E;PDE6D;RPGR,"Phosphatidylinositol polyphosphate 5-phosphatase type IV;Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta;X-linked retinitis pigmentosa GTPase regulator",GO:0006886;GO:0044782;GO:0061512,intracellular protein transport;cilium organization;protein localization to cilium,biological_process;biological_process;biological_process,ENSP00000360777;ENSP00000287600;ENSP00000495537,1,1,0,0
6749,ITGB1BP1-KRIT1-RAP1A complex,17916086,ITGB1BP1;KRIT1;RAP1A,Integrin beta-1-binding protein 1;Krev interaction trapped protein 1;Ras-related protein Rap-1A,GO:0005546;GO:0005886,"phosphatidylinositol-4,5-bisphosphate binding;plasma membrane",molecular_function;cellular_component,ENSP00000353850;ENSP00000378015;ENSP00000358723,0,0,0,0
6753,SOG complex,28199315,MIOS;NPRL2;NPRL3;SEC13;SEH1L;SZT2;WDR24;WDR59,GATOR2 complex protein MIOS;GATOR1 complex protein NPRL2;GATOR1 complex protein NPRL3;Protein SEC13 homolog;Nucleoporin SEH1;KICSTOR complex protein SZT2;GATOR2 complex protein WDR24;GATOR2 complex protein WDR59,GO:0032418;GO:1904262,lysosome localization;negative regulation of TORC1 signaling,biological_process;biological_process,ENSP00000339881;ENSP00000232501;ENSP00000483814;ENSP00000373312;ENSP00000382779;ENSP00000457168;ENSP00000293883;ENSP00000262144,0,0,0,0
6780,RAD6A-KCMF1-UBR4 complex,25582440,KCMF1;UBE2A;UBR4,E3 ubiquitin-protein ligase KCMF1;Ubiquitin-conjugating enzyme E2 A;E3 ubiquitin-protein ligase UBR4,GO:1905146,lysosomal protein catabolic process,biological_process,ENSP00000386738;ENSP00000360613;ENSP00000364403,0,0,0,0
6802,KDR-MAPK1-MAPK3-PRKCA-S1PR5 complex,20501673,KDR;MAPK1;MAPK3;PRKCA;S1PR5,Vascular endothelial growth factor receptor 2;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 3;Protein kinase C alpha type;Sphingosine 1-phosphate receptor 5,GO:0007186;GO:0016477;GO:0035924;GO:0048010;GO:0070371,G protein-coupled receptor signaling pathway;cell migration;cellular response to vascular endothelial growth factor stimulus;vascular endothelial growth factor receptor signaling pathway;ERK1 and ERK2 cascade,biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000263923;ENSP00000215832;ENSP00000263025;ENSP00000408695;ENSP00000328472,0,0,0,0
6815,CUL3-DRD4-KLHL12 complex,18303015,CUL3;DRD4;KLHL12,Cullin-3;D(4) dopamine receptor;Kelch-like protein 12,GO:0007186;GO:0031396,G protein-coupled receptor signaling pathway;regulation of protein ubiquitination,biological_process;biological_process,ENSP00000264414;ENSP00000176183;ENSP00000356230,0,0,0,0
6844,NIF-1-DBC1-EMSY complex,19131338,CCAR2;EMSY;ZNF335,Cell cycle and apoptosis regulator protein 2;BRCA2-interacting transcriptional repressor EMSY;Zinc finger protein 335,GO:0006351;GO:0048384,DNA-templated transcription;retinoic acid receptor signaling pathway,biological_process;biological_process,ENSP00000310670;ENSP00000433205;ENSP00000325326,0,0,0,0
6858,CHTOP-ERH-PRMT1-PRMT5-WDR77 complex,25284789,CHTOP;ERH;PRMT1;PRMT5;WDR77,Chromatin target of PRMT1 protein;Enhancer of rudimentary homolog;Protein arginine N-methyltransferase 1;Protein arginine N-methyltransferase 5;Methylosome protein WDR77,GO:0002056;GO:0006355;GO:0044020,cytosine binding;regulation of DNA-templated transcription;histone H4R3 methyltransferase activity,molecular_function;biological_process;molecular_function,ENSP00000357679;ENSP00000451080;ENSP00000406162;ENSP00000319169;ENSP00000235090,0,0,0,0
6889,TBC1D7-TSC1-TSC2 complex,24529379,TBC1D7;TSC1;TSC2,TBC1 domain family member 7;Hamartin;Tuberin,GO:0005764;GO:0008286;GO:0009594;GO:0043491;GO:1904263,lysosome;insulin receptor signaling pathway;detection of nutrient;phosphatidylinositol 3-kinase/protein kinase B signal transduction;positive regulation of TORC1 signaling,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000475727;ENSP00000298552;ENSP00000219476,0,0,0,0
6906,FBXW7-CDX2-GSK3B complex,27470268,CDX2;FBXW7;GSK3B,Homeobox protein CDX-2;F-box/WD repeat-containing protein 7;Glycogen synthase kinase-3 beta,GO:0006511;GO:0031146,ubiquitin-dependent protein catabolic process;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,biological_process;biological_process,ENSP00000370408;ENSP00000474725;ENSP00000324806,0,0,0,0
6908,CTNNB1-FERMT2-YBX1 complex,27713156,CTNNB1;FERMT2;YBX1,Catenin beta-1;Fermitin family homolog 2;Y-box-binding protein 1,GO:0005634;GO:0005737;GO:0006355;GO:1901186,nucleus;cytoplasm;regulation of DNA-templated transcription;positive regulation of ERBB signaling pathway,cellular_component;cellular_component;biological_process;biological_process,ENSP00000495360;ENSP00000342858;ENSP00000361626,20,20,0,0
6910,EED-EZH2-PHF19 complex,21143197,EED;EZH2;PHF19,Polycomb protein EED;Histone-lysine N-methyltransferase EZH2;PHD finger protein 19,GO:0005634,nucleus,cellular_component,ENSP00000338186;ENSP00000320147;ENSP00000483946,3,3,0,0
6930,PRKCZ-VAMP2-WDFY2 complex,17313651,PRKCZ;VAMP2;WDFY2,Protein kinase C zeta type;Vesicle-associated membrane protein 2;WD repeat and FYVE domain-containing protein 2,GO:0036465,synaptic vesicle recycling,biological_process,ENSP00000367830;ENSP00000418572;ENSP00000298125,0,0,0,0
6939,Norrin receptor complex,19837033,FZD4;LRP5;NDP;TSPAN12,Frizzled-4;Low-density lipoprotein receptor-related protein 5;Norrin;Tetraspanin-12,GO:0005886;GO:0007166,plasma membrane;cell surface receptor signaling pathway,cellular_component;biological_process,ENSP00000434034;ENSP00000294304;ENSP00000495811;ENSP00000222747,0,0,0,0
6953,ARTN-GFRA3-RET comples,9883723,ARTN;GFRA3;RET,Artemin;GDNF family receptor alpha-3;Proto-oncogene tyrosine-protein kinase receptor Ret,GO:0007399,nervous system development,biological_process,ENSP00000387435;ENSP00000274721;ENSP00000347942,0,0,0,0
6956,REP-RGGT-Rab complex,18532927,CHM;RAB3A;RABGGTA,Rab proteins geranylgeranyltransferase component A 1;Ras-related protein Rab-3A;Geranylgeranyl transferase type-2 subunit alpha,GO:2000539,regulation of protein geranylgeranylation,biological_process,ENSP00000350386;ENSP00000222256;ENSP00000382341,0,0,0,0
6960,BICD2-dynein-dynactin complex,28883039,BICD2;DCTN1;DYNC1I1,Protein bicaudal D homolog 2;Dynactin subunit 1;Cytoplasmic dynein 1 intermediate chain 1,GO:0060236,regulation of mitotic spindle organization,biological_process,ENSP00000349351;ENSP00000354791;ENSP00000320130,0,0,0,0
6969,"Serine-palmitoyltransferase (SPTLC1, SPTLC2, SPTLC3) complex",17331073,SPTLC1;SPTLC2;SPTLC3,Serine palmitoyltransferase 1;Serine palmitoyltransferase 2;Serine palmitoyltransferase 3,GO:0002178;GO:0005783;GO:0016409;GO:0030148,palmitoyltransferase complex;endoplasmic reticulum;palmitoyltransferase activity;sphingolipid biosynthetic process,cellular_component;cellular_component;molecular_function;biological_process,ENSP00000262554;ENSP00000216484;ENSP00000381968,0,0,0,0
6970,"Serine-palmitoyltransferase (SPTLC1, SPTLC3, ssSPTb) complex",19416851,SPTLC1;SPTLC3;SPTSSB,Serine palmitoyltransferase 1;Serine palmitoyltransferase 3;Serine palmitoyltransferase small subunit B,GO:0002178;GO:0005783;GO:0016409;GO:0030148,palmitoyltransferase complex;endoplasmic reticulum;palmitoyltransferase activity;sphingolipid biosynthetic process,cellular_component;cellular_component;molecular_function;biological_process,ENSP00000262554;ENSP00000381968;ENSP00000352097,0,0,0,0
6972,"Serine-palmitoyltransferase (SPTLC1, SPTLC3, ssSPTa) complex",19416851,SPTLC1;SPTLC3;SPTSSA,Serine palmitoyltransferase 1;Serine palmitoyltransferase 3;Serine palmitoyltransferase small subunit A,GO:0002178;GO:0005783;GO:0016409;GO:0030148,palmitoyltransferase complex;endoplasmic reticulum;palmitoyltransferase activity;sphingolipid biosynthetic process,cellular_component;cellular_component;molecular_function;biological_process,ENSP00000262554;ENSP00000381968;ENSP00000298130,0,0,0,0
6973,"Serine-palmitoyltransferase (SPTLC1, SPTLC2, ssSPTb) complex",19416851,SPTLC1;SPTLC2;SPTSSB,Serine palmitoyltransferase 1;Serine palmitoyltransferase 2;Serine palmitoyltransferase small subunit B,GO:0002178;GO:0005783;GO:0016409;GO:0030148,palmitoyltransferase complex;endoplasmic reticulum;palmitoyltransferase activity;sphingolipid biosynthetic process,cellular_component;cellular_component;molecular_function;biological_process,ENSP00000262554;ENSP00000216484;ENSP00000352097,0,0,0,0
6974,"Serine-palmitoyltransferase (SPTLC1, SPTLC2, ssSPTa) complex",19416851,SPTLC1;SPTLC2;SPTSSA,Serine palmitoyltransferase 1;Serine palmitoyltransferase 2;Serine palmitoyltransferase small subunit A,GO:0002178;GO:0005783;GO:0016409;GO:0030148,palmitoyltransferase complex;endoplasmic reticulum;palmitoyltransferase activity;sphingolipid biosynthetic process,cellular_component;cellular_component;molecular_function;biological_process,ENSP00000262554;ENSP00000216484;ENSP00000298130,1,1,0,0
6975,JUN-FBW7-PRR7 complex,27458189,FBXW7;JUN;PRR7,F-box/WD repeat-containing protein 7;Transcription factor Jun;Proline-rich protein 7,GO:0043506,regulation of JUN kinase activity,biological_process,ENSP00000474725;ENSP00000360266;ENSP00000327168,0,0,0,0
6990,PTK2-THSD1-TLN1-VCL complex ,29069646,PTK2;THSD1;TLN1;VCL,Focal adhesion kinase 1;Thrombospondin type-1 domain-containing protein 1;Talin-1;Vinculin,GO:0017166;GO:0051893;GO:1990147,vinculin binding;regulation of focal adhesion assembly;talin binding,molecular_function;biological_process;molecular_function,ENSP00000341189;ENSP00000258613;ENSP00000316029;ENSP00000211998,0,0,0,0
6991,ABI3-WAVE2-CYFIP1 complex,28978070,ABI3;CYFIP1;WASF2,ABI gene family member 3;Cytoplasmic FMR1-interacting protein 1;Actin-binding protein WASF2,GO:0051896,regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process,ENSP00000225941;ENSP00000481038;ENSP00000483313,0,0,0,0
7004,HTT-DISC1-PDE4B complex,28263187,DISC1;HTT;PDE4B,"Disrupted in schizophrenia 1 protein;Huntingtin;3',5'-cyclic-AMP phosphodiesterase 4B",GO:0004115,"3',5'-cyclic-AMP phosphodiesterase activity",molecular_function,ENSP00000403888;ENSP00000347184;ENSP00000342637,53,0,0,53
7005,GRIN3A-PP2A complex,11588171,GRIN3A;PPP2CA;PPP2R1A;PPP2R2A,"Glutamate receptor ionotropic, NMDA 3A;Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform;Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform",GO:0004721;GO:0048167,phosphoprotein phosphatase activity;regulation of synaptic plasticity,molecular_function;biological_process,ENSP00000355155;ENSP00000418447;ENSP00000324804;ENSP00000325074,0,0,0,0
7014,"Heterotrimeric G protein complex (GNAI1, GNB1, GNGT1)",25733868,GNAI1;GNB1;GNGT1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000248572,2,2,0,0
7015,"Heterotrimeric G protein complex (GNAI1, GNB2, GNGT1)",25733868,GNAI1;GNB2;GNGT1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000248572,0,0,0,0
7016,"Heterotrimeric G protein complex (GNAI1, GNB3, GNGT1)",25733868,GNAI1;GNB3;GNGT1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000248572,0,0,0,0
7017,"Heterotrimeric G protein complex (GNAI1, GNB4, GNGT1)",25733868,GNAI1;GNB4;GNGT1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000248572,0,0,0,0
7018,"Heterotrimeric G protein complex (GNAI1, GNB5, GNGT1) ",25733868,GNAI1;GNB5;GNGT1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000248572,1,1,0,0
7019,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG2)",25733868,GNAI1;GNB1;GNG2,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000334448,61,61,61,0
7020,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG2)",25733868,GNAI1;GNB2;GNG2,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000334448,0,0,0,0
7021,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG2)",25733868,GNAI1;GNB3;GNG2,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000334448,0,0,0,0
7022,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG2)",25733868,GNAI1;GNB4;GNG2,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000334448,0,0,0,0
7023,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG2)",25733868,GNAI1;GNB5;GNG2,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000334448,62,62,62,0
7024,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG3)",25733868,GNAI1;GNB1;GNG3,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000294117,0,0,0,0
7025,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG3)",25733868,GNAI1;GNB2;GNG3,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000294117,0,0,0,0
7026,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG3)",25733868,GNAI1;GNB3;GNG3,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000294117,0,0,0,0
7027,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG3)",25733868,GNAI1;GNB4;GNG3,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000294117,0,0,0,0
7028,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG3)",25733868,GNAI1;GNB5;GNG3,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000294117,0,0,0,0
7031,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG4)",25733868,GNAI1;GNB1;GNG4,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000398629,0,0,0,0
7032,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG4)",25733868,GNAI1;GNB2;GNG4,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000398629,0,0,0,0
7033,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG4)",25733868,GNAI1;GNB3;GNG4,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000398629,0,0,0,0
7034,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG4)",25733868,GNAI1;GNB4;GNG4,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000398629,0,0,0,0
7035,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG4)",25733868,GNAI1;GNB5;GNG4,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000398629,0,0,0,0
7036,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG5)",25733868,GNAI1;GNB1;GNG5,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000359675,0,0,0,0
7037,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG5)",25733868,GNAI1;GNB2;GNG5,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000359675,0,0,0,0
7040,PDZK1-PLCB3-SSTR5 complex,22528496,PDZK1;PLCB3;SSTR5,"Na(+)/H(+) exchange regulatory cofactor NHE-RF3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;Somatostatin receptor type 5",GO:0007186;GO:0031882;GO:0038170,G protein-coupled receptor signaling pathway;type 5 somatostatin receptor binding;somatostatin signaling pathway,biological_process;molecular_function;biological_process,ENSP00000342143;ENSP00000443631;ENSP00000293897,0,0,0,0
7041,PDZK1-PLCB3-SSTR1 complex,22528496,PDZK1;PLCB3;SSTR1,"Na(+)/H(+) exchange regulatory cofactor NHE-RF3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;Somatostatin receptor type 1",GO:0007186;GO:0031878;GO:0038170,G protein-coupled receptor signaling pathway;type 1 somatostatin receptor binding;somatostatin signaling pathway,biological_process;molecular_function;biological_process,ENSP00000342143;ENSP00000443631;ENSP00000267377,0,0,0,0
7042,PDZK1-PLCB3-SSTR2 complex,22528496,PDZK1;PLCB3;SSTR2,"Na(+)/H(+) exchange regulatory cofactor NHE-RF3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;Somatostatin receptor type 2",GO:0007186;GO:0031879;GO:0038170,G protein-coupled receptor signaling pathway;type 2 somatostatin receptor binding;somatostatin signaling pathway,biological_process;molecular_function;biological_process,ENSP00000342143;ENSP00000443631;ENSP00000350198,1,0,0,1
7043,PDZK1-PLCB3-SSTR3 complex,22528496,PDZK1;PLCB3;SSTR3,"Na(+)/H(+) exchange regulatory cofactor NHE-RF3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;Somatostatin receptor type 3",GO:0007186;GO:0031880;GO:0038170,G protein-coupled receptor signaling pathway;type 3 somatostatin receptor binding;somatostatin signaling pathway,biological_process;molecular_function;biological_process,ENSP00000342143;ENSP00000443631;ENSP00000480971,0,0,0,0
7044,PDZK1-PLCB3-SSTR4 complex,22528496,PDZK1;PLCB3;SSTR4,"Na(+)/H(+) exchange regulatory cofactor NHE-RF3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;Somatostatin receptor type 4",GO:0007186;GO:0031881;GO:0038170,G protein-coupled receptor signaling pathway;type 4 somatostatin receptor binding;somatostatin signaling pathway,biological_process;molecular_function;biological_process,ENSP00000342143;ENSP00000443631;ENSP00000255008,0,0,0,0
7058,HEG1-KRIT1-RAP1B complex,23814056,HEG1;KRIT1;RAP1B,Protein HEG homolog 1;Krev interaction trapped protein 1;Ras-related protein Rap-1b,GO:0003924;GO:0005886,GTPase activity;plasma membrane,molecular_function;cellular_component,ENSP00000311502;ENSP00000378015;ENSP00000250559,2,2,0,0
7059,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG5)",25733868,GNAI1;GNB3;GNG5,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000359675,0,0,0,0
7060,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG5)",25733868,GNAI1;GNB4;GNG5,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000359675,0,0,0,0
7061,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG5)",25733868,GNAI1;GNB5;GNG5,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000359675,0,0,0,0
7063,C9orf72-SMCR8-WDR41 complex,27193190,C9orf72;SMCR8;WDR41,Guanine nucleotide exchange factor C9orf72;Guanine nucleotide exchange protein SMCR8;WD repeat-containing protein 41,GO:0000139;GO:0006914,Golgi membrane;autophagy,cellular_component;biological_process,ENSP00000482753;ENSP00000385025;ENSP00000296679,2,2,2,0
7065,WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex,27193190,ATG101;ATG13;C9orf72;RB1CC1;SMCR8;ULK1;WDR41,Autophagy-related protein 101;Autophagy-related protein 13;Guanine nucleotide exchange factor C9orf72;RB1-inducible coiled-coil protein 1;Guanine nucleotide exchange protein SMCR8;Serine/threonine-protein kinase ULK1;WD repeat-containing protein 41,GO:0000139;GO:0006914,Golgi membrane;autophagy,cellular_component;biological_process,ENSP00000338990;ENSP00000432412;ENSP00000482753;ENSP00000025008;ENSP00000385025;ENSP00000324560;ENSP00000296679,0,0,0,0
7066,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG7)",25733868,GNAI1;GNB1;GNG7,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000371594,0,0,0,0
7067,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG7)",25733868,GNAI1;GNB2;GNG7,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000371594,0,0,0,0
7068,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG7)",25733868,GNAI1;GNB3;GNG7,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000371594,0,0,0,0
7069,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG7)",25733868,GNAI1;GNB4;GNG7,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000371594,0,0,0,0
7070,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG7)",25733868,GNAI1;GNB5;GNG7,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000371594,0,0,0,0
7071,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG8)",25733868,GNAI1;GNB1;GNG8,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000300873,0,0,0,0
7072,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG8)",25733868,GNAI1;GNB2;GNG8,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000300873,0,0,0,0
7073,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG8)",25733868,GNAI1;GNB3;GNG8,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000300873,0,0,0,0
7074,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG8)",25733868,GNAI1;GNB4;GNG8,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000300873,0,0,0,0
7075,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG8)",25733868,GNAI1;GNB5;GNG8,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000300873,0,0,0,0
7076,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG10)",25733868,GNAI1;GNB1;GNG10,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000363411,0,0,0,0
7077,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG10)",25733868,GNAI1;GNB2;GNG10,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000363411,0,0,0,0
7078,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG10)",25733868,GNAI1;GNB3;GNG10,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000363411,0,0,0,0
7079,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG10)",25733868,GNAI1;GNB4;GNG10,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000363411,0,0,0,0
7080,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG10)",25733868,GNAI1;GNB5;GNG10,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000363411,0,0,0,0
7081,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG11)",25733868,GNAI1;GNB1;GNG11,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000248564,0,0,0,0
7082,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG11)",25733868,GNAI1;GNB2;GNG11,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000248564,0,0,0,0
7083,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG11)",25733868,GNAI1;GNB3;GNG11,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000248564,0,0,0,0
7084,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG11)",25733868,GNAI1;GNB4;GNG11,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000248564,0,0,0,0
7085,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG11)",25733868,GNAI1;GNB5;GNG11,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000248564,0,0,0,0
7086,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG12)",25733868,GNAI1;GNB1;GNG12,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000360021,0,0,0,0
7087,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG12)",25733868,GNAI1;GNB2;GNG12,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000360021,0,0,0,0
7088,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG12)",25733868,GNAI1;GNB3;GNG12,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000360021,0,0,0,0
7089,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG12)",25733868,GNAI1;GNB4;GNG12,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000360021,0,0,0,0
7090,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG12)",25733868,GNAI1;GNB5;GNG12,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000360021,0,0,0,0
7092,"Heterotrimeric G protein complex (GNAI1, GNB1, GNG13)",25733868,GNAI1;GNB1;GNG13,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000367872;ENSP00000248150,0,0,0,0
7093,"Heterotrimeric G protein complex (GNAI1, GNB2, GNG13)",25733868,GNAI1;GNB2;GNG13,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000305260;ENSP00000248150,0,0,0,0
7094,"Heterotrimeric G protein complex (GNAI1, GNB3, GNG13)",25733868,GNAI1;GNB3;GNG13,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000229264;ENSP00000248150,0,0,0,0
7095,"Heterotrimeric G protein complex (GNAI1, GNB4, GNG13)",25733868,GNAI1;GNB4;GNG13,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000232564;ENSP00000248150,0,0,0,0
7096,"Heterotrimeric G protein complex (GNAI1, GNB5, GNG13)",25733868,GNAI1;GNB5;GNG13,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000497260;ENSP00000261837;ENSP00000248150,0,0,0,0
7097,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNGT1)",25733868,GNAS;GNB1;GNGT1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000248572,2,2,0,0
7130,PRKAR2A-GSKIP-GSK3B-DNM1L complex,25920809,DNM1L;GSK3B;GSKIP;PRKAR2A,Dynamin-1-like protein;Glycogen synthase kinase-3 beta;GSK3B-interacting protein;cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0006468;GO:0006979;GO:0070125,protein phosphorylation;response to oxidative stress;mitochondrial translational elongation,biological_process;biological_process;biological_process,ENSP00000449089;ENSP00000324806;ENSP00000451188;ENSP00000265563,1,1,0,1
7143,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNGT1)",25733868,GNAS;GNB2;GNGT1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000248572,0,0,0,0
7144,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNGT1)",25733868,GNAS;GNB3;GNGT1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000248572,0,0,0,0
7145,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNGT1)",25733868,GNAS;GNB4;GNGT1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000248572,0,0,0,0
7146,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNGT1)",25733868,GNAS;GNB5;GNGT1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(T) subunit gamma-T1,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000248572,3,3,0,0
7148,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG2)",25733868,GNAS;GNB2;GNG2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000334448,0,0,0,0
7149,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG2)",25733868,GNAS;GNB3;GNG2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000334448,0,0,0,0
7150,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG2)",25733868,GNAS;GNB4;GNG2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000334448,0,0,0,0
7151,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG2)",25733868,GNAS;GNB5;GNG2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000334448,81,81,81,0
7152,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG3)",25733868,GNAS;GNB1;GNG3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000294117,0,0,0,0
7153,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG3)",25733868,GNAS;GNB2;GNG3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000294117,0,0,0,0
7154,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG3)",25733868,GNAS;GNB3;GNG3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000294117,0,0,0,0
7155,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG3)",25733868,GNAS;GNB4;GNG3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000294117,0,0,0,0
7156,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG3)",25733868,GNAS;GNB5;GNG3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000294117,0,0,0,0
7159,TSC2-GSK3-AXIN-DVL complex,15972957,AXIN1;DVL1;GSK3B;TSC2,Axin-1;Segment polarity protein dishevelled homolog DVL-1;Glycogen synthase kinase-3 beta;Tuberin,GO:0030111;GO:0033596,regulation of Wnt signaling pathway;TSC1-TSC2 complex,biological_process;cellular_component,ENSP00000262320;ENSP00000368166;ENSP00000324806;ENSP00000219476,0,0,0,0
7164,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG4)",25733868,GNAS;GNB5;GNG4,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000398629,0,0,0,0
7165,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG5)",25733868,GNAS;GNB1;GNG5,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000359675,0,0,0,0
7166,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG5)",25733868,GNAS;GNB2;GNG5,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000359675,0,0,0,0
7167,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG5)",25733868,GNAS;GNB3;GNG5,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000359675,0,0,0,0
7168,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG5)",25733868,GNAS;GNB4;GNG5,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000359675,0,0,0,0
7169,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG5)",25733868,GNAS;GNB5;GNG5,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000359675,0,0,0,0
7170,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG7)",25733868,GNAS;GNB1;GNG7,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000371594,0,0,0,0
7171,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG7)",25733868,GNAS;GNB2;GNG7,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000371594,0,0,0,0
7172,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG7)",25733868,GNAS;GNB3;GNG7,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000371594,0,0,0,0
7173,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG7)",25733868,GNAS;GNB4;GNG7,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000371594,0,0,0,0
7174,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG7)",25733868,GNAS;GNB5;GNG7,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000371594,0,0,0,0
7175,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG8)",25733868,GNAS;GNB1;GNG8,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000300873,0,0,0,0
7176,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG8)",25733868,GNAS;GNB2;GNG8,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000300873,0,0,0,0
7177,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG8)",25733868,GNAS;GNB3;GNG8,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000300873,0,0,0,0
7178,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG8)",25733868,GNAS;GNB4;GNG8,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000300873,0,0,0,0
7179,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG8)",25733868,GNAS;GNB5;GNG8,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000300873,0,0,0,0
7187,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG10)",25733868,GNAS;GNB1;GNG10,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000363411,0,0,0,0
7188,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG10)",25733868,GNAS;GNB2;GNG10,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000363411,0,0,0,0
7189,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG10)",25733868,GNAS;GNB3;GNG10,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000363411,0,0,0,0
7193,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG10)",25733868,GNAS;GNB4;GNG10,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000363411,0,0,0,0
7194,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG10)",25733868,GNAS;GNB5;GNG10,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000363411,0,0,0,0
7195,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG11)",25733868,GNAS;GNB1;GNG11,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000248564,0,0,0,0
7199,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG11)",25733868,GNAS;GNB2;GNG11,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000248564,0,0,0,0
7201,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG11)",25733868,GNAS;GNB3;GNG11,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000248564,0,0,0,0
7202,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG11)",25733868,GNAS;GNB4;GNG11,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000248564,0,0,0,0
7208,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG12)",25733868,GNAS;GNB5;GNG12,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000360021,0,0,0,0
7209,"Heterotrimeric G protein complex (GNAS-L, GNB1, GNG13)",25733868,GNAS;GNB1;GNG13,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000248150,0,0,0,0
7210,"Heterotrimeric G protein complex (GNAS-L, GNB2, GNG13)",25733868,GNAS;GNB2;GNG13,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000305260;ENSP00000248150,0,0,0,0
7211,"Heterotrimeric G protein complex (GNAS-L, GNB3, GNG13)",25733868,GNAS;GNB3;GNG13,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000229264;ENSP00000248150,0,0,0,0
7212,"Heterotrimeric G protein complex (GNAS-L, GNB4, GNG13)",25733868,GNAS;GNB4;GNG13,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000232564;ENSP00000248150,0,0,0,0
7213,"Heterotrimeric G protein complex (GNAS-L, GNB5, GNG13)",25733868,GNAS;GNB5;GNG13,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein subunit beta-5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13,GO:0005834;GO:0007165;GO:0008277,heterotrimeric G-protein complex;signal transduction;regulation of G protein-coupled receptor signaling pathway,cellular_component;biological_process;biological_process,ENSP00000360141;ENSP00000261837;ENSP00000248150,0,0,0,0
7218,DTNBP1(splice variant 1B)-PRKDC-XRCC5-XRCC6 complex,19142223,DTNBP1;PRKDC;XRCC5;XRCC6,Dysbindin;DNA-dependent protein kinase catalytic subunit;X-ray repair cross-complementing protein 5;X-ray repair cross-complementing protein 6,GO:0006355,regulation of DNA-templated transcription,biological_process,ENSP00000341680;ENSP00000313420;ENSP00000375978;ENSP00000352257,0,0,0,0
7234,DLGAP1-DLG4-DYNLL2 complex,10844022,DLG4;DLGAP1;DYNLL2,"Disks large homolog 4;Disks large-associated protein 1;Dynein light chain 2, cytoplasmic",,,,ENSP00000497806;ENSP00000316377;ENSP00000477310,27,27,27,0
7265,"MLC1-Na,K-ATPase-Kir4.1-AQP4-TRPV4-syntrophin complex",22328087,AQP4;ATP1B1;KCNJ10;MLC1;SNTG1;TRPV4,Aquaporin-4;Sodium/potassium-transporting ATPase subunit beta-1;ATP-sensitive inward rectifier potassium channel 10;Membrane protein MLC1;Gamma-1-syntrophin;Transient receptor potential cation channel subfamily V member 4,GO:0005886;GO:0009992,plasma membrane;intracellular water homeostasis,cellular_component;biological_process,ENSP00000372654;ENSP00000356790;ENSP00000495557;ENSP00000310375;ENSP00000493900;ENSP00000406191,0,0,0,0
7268,"HEPACAM-MLC1-Na,K-ATPase-Kir4.1-AQP4-TRPV4 complex",22328087,AQP4;ATP1B1;HEPACAM;KCNJ10;MLC1;TRPV4,Aquaporin-4;Sodium/potassium-transporting ATPase subunit beta-1;Hepatic and glial cell adhesion molecule;ATP-sensitive inward rectifier potassium channel 10;Membrane protein MLC1;Transient receptor potential cation channel subfamily V member 4,GO:0005886;GO:0009992,plasma membrane;intracellular water homeostasis,cellular_component;biological_process,ENSP00000372654;ENSP00000356790;ENSP00000298251;ENSP00000495557;ENSP00000310375;ENSP00000406191,0,0,0,0
7284,GSK3B-HSP90AA1-PKM2 complex,29262861,GSK3B;HSP90AA1;PKM,Glycogen synthase kinase-3 beta;Heat shock protein HSP 90-alpha;Pyruvate kinase PKM,GO:0001932,regulation of protein phosphorylation,biological_process,ENSP00000324806;ENSP00000335153;ENSP00000320171,141,141,0,141
7291,EIF2B2-EIF2B3-EIF2B4-EIF2B5 complex,24532666,EIF2B2;EIF2B3;EIF2B4;EIF2B5,Translation initiation factor eIF2B subunit beta;Translation initiation factor eIF2B subunit gamma;Translation initiation factor eIF2B subunit delta;Translation initiation factor eIF2B subunit epsilon,GO:0003743;GO:0006446,translation initiation factor activity;regulation of translational initiation,molecular_function;biological_process,ENSP00000266126;ENSP00000353575;ENSP00000429323;ENSP00000497160,0,0,0,0
7292,EIF2B1-EIF2B2-EIF2B3-EIF2B4-EIF2B5 complex,24532666,EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5,Translation initiation factor eIF2B subunit alpha;Translation initiation factor eIF2B subunit beta;Translation initiation factor eIF2B subunit gamma;Translation initiation factor eIF2B subunit delta;Translation initiation factor eIF2B subunit epsilon,GO:0003743;GO:0006446,translation initiation factor activity;regulation of translational initiation,molecular_function;biological_process,ENSP00000416250;ENSP00000266126;ENSP00000353575;ENSP00000429323;ENSP00000497160,0,0,0,0
7300,PARD3B-PARD6A-PRKCI complex,11260256,PARD3B;PARD6A;PRKCI,Partitioning defective 3 homolog B;Partitioning defective 6 homolog alpha;Protein kinase C iota type,GO:0043297,apical junction assembly,biological_process,ENSP00000385848;ENSP00000219255;ENSP00000295797,0,0,0,0
7358,NDFIP1-NEDD4L-SLC11A2 complex,19706893,NDFIP1;NEDD4L;SLC11A2,NEDD4 family-interacting protein 1;E3 ubiquitin-protein ligase NEDD4-like;Natural resistance-associated macrophage protein 2,GO:0010039;GO:0016567;GO:0030001;GO:0032025,response to iron ion;protein ubiquitination;metal ion transport;response to cobalt ion,biological_process;biological_process;biological_process;biological_process,ENSP00000253814;ENSP00000383199;ENSP00000378364,0,0,0,0
7368,"Ubiquitin E3 ligase (CUL3, KEAP1, RBX1)",15983046,CUL3;KEAP1;RBX1,Cullin-3;Kelch-like ECH-associated protein 1;E3 ubiquitin-protein ligase RBX1,GO:0031463;GO:0043161,Cul3-RING ubiquitin ligase complex;proteasome-mediated ubiquitin-dependent protein catabolic process,cellular_component;biological_process,ENSP00000264414;ENSP00000377245;ENSP00000216225,5,5,0,0
7379,FYN-KHDRBS1-PLCG1 complex,14647465,FYN;KHDRBS1;PLCG1,"Tyrosine-protein kinase Fyn;KH domain-containing, RNA-binding, signal transduction-associated protein 1;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1",GO:0051252,regulation of RNA metabolic process,biological_process,ENSP00000346671;ENSP00000313829;ENSP00000244007,5,5,0,0
7381,DCS complex,11003644,HNRNPH1;KHSRP;PTBP1;PTBP2,Heterogeneous nuclear ribonucleoprotein H;Far upstream element-binding protein 2;Polypyrimidine tract-binding protein 1;Polypyrimidine tract-binding protein 2,GO:0005634;GO:0070054,"nucleus;mRNA splicing, via endonucleolytic cleavage and ligation",cellular_component;biological_process,ENSP00000349168;ENSP00000381216;ENSP00000349428;ENSP00000359216,0,0,0,0
7389,KCNA1-KCNA2-KCNAB2 complex,11086297,KCNA1;KCNA2;KCNAB2,Potassium voltage-gated channel subfamily A member 1;Potassium voltage-gated channel subfamily A member 2;Voltage-gated potassium channel subunit beta-2,GO:0005249;GO:0005267;GO:0008076;GO:0034705;GO:0071805,voltage-gated potassium channel activity;potassium channel activity;voltage-gated potassium channel complex;potassium channel complex;potassium ion transmembrane transport,molecular_function;molecular_function;cellular_component;cellular_component;biological_process,ENSP00000371985;ENSP00000487785;ENSP00000367323,0,0,0,0
7408,"ARRB1-ARHGEF18-ENAH complex, induce by EDN-1",29439204,ARHGEF18;ARRB1;ENAH,Rho guanine nucleotide exchange factor 18;Beta-arrestin-1;Protein enabled homolog,,,,ENSP00000482647;ENSP00000409581;ENSP00000355809,0,0,0,0
7462,"GABA-A receptor (GABRA1, GABRB2, GABRD)",27493204,GABRA1;GABRB2;GABRD,Gamma-aminobutyric acid receptor subunit alpha-1;Gamma-aminobutyric acid receptor subunit beta-2;Gamma-aminobutyric acid receptor subunit delta,GO:0004890;GO:1902476,GABA-A receptor activity;chloride transmembrane transport,molecular_function;biological_process,ENSP00000393097;ENSP00000274547;ENSP00000367848,103,103,0,0
7517,"Ubiquitin E3 ligase (CUL3, KLHL7, RBX1)",21828050,CUL3;KLHL7;RBX1,Cullin-3;Kelch-like protein 7;E3 ubiquitin-protein ligase RBX1,GO:0031461;GO:0043161,cullin-RING ubiquitin ligase complex;proteasome-mediated ubiquitin-dependent protein catabolic process,cellular_component;biological_process,ENSP00000264414;ENSP00000343273;ENSP00000216225,4,4,0,0
7555,KEOPS complex,22912744,LAGE3;OSGEP;TP53RK;TPRKB,EKC/KEOPS complex subunit LAGE3;tRNA N6-adenosine threonylcarbamoyltransferase;EKC/KEOPS complex subunit TP53RK;EKC/KEOPS complex subunit TPRKB,GO:0000723;GO:0006412,telomere maintenance;translation,biological_process;biological_process,ENSP00000349923;ENSP00000206542;ENSP00000361186;ENSP00000325398,1,1,1,0
7557,LGR4-RSPO supercomplex,24639526,DIAPH1;DVL2;IQGAP1;LGR4;MAP2K1;MAP2K2;PTK2;PXN;RSPO3;WASL,Protein diaphanous homolog 1;Segment polarity protein dishevelled homolog DVL-2;Ras GTPase-activating-like protein IQGAP1;Leucine-rich repeat-containing G-protein coupled receptor 4;Dual specificity mitogen-activated protein kinase kinase 1;Dual specificity mitogen-activated protein kinase kinase 2;Focal adhesion kinase 1;Paxillin;R-spondin-3;Actin nucleation-promoting factor WASL,GO:0007186;GO:0016055;GO:0048041,G protein-coupled receptor signaling pathway;Wnt signaling pathway;focal adhesion assembly,biological_process;biological_process;biological_process,ENSP00000373706;ENSP00000005340;ENSP00000268182;ENSP00000368516;ENSP00000302486;ENSP00000262948;ENSP00000341189;ENSP00000267257;ENSP00000349131;ENSP00000223023,0,0,0,0
7577,APBB1-APP-KAT5 complex,11441186,APBB1;APP;KAT5,Amyloid beta precursor protein binding family B member 1;Amyloid-beta precursor protein;Histone acetyltransferase KAT5,GO:0001221;GO:0001540;GO:0003677;GO:0009299,transcription coregulator binding;amyloid-beta binding;DNA binding;mRNA transcription,molecular_function;molecular_function;molecular_function;biological_process,ENSP00000477213;ENSP00000284981;ENSP00000340330,0,0,0,0
7581,ESR1-Mediator complex,11867769,CCNC;CDK8;EP300;ESR1;MED1;MED10;MED12;MED13;MED14;MED16;MED17;MED20;MED21;MED23;MED24;MED6;MED7;NCOA1,Cyclin-C;Cyclin-dependent kinase 8;Histone acetyltransferase p300;Estrogen receptor;Mediator of RNA polymerase II transcription subunit 1;Mediator of RNA polymerase II transcription subunit 10;Mediator of RNA polymerase II transcription subunit 12;Mediator of RNA polymerase II transcription subunit 13;Mediator of RNA polymerase II transcription subunit 14;Mediator of RNA polymerase II transcription subunit 16;Mediator of RNA polymerase II transcription subunit 17;Mediator of RNA polymerase II transcription subunit 20;Mediator of RNA polymerase II transcription subunit 21;Mediator of RNA polymerase II transcription subunit 23;Mediator of RNA polymerase II transcription subunit 24;Mediator of RNA polymerase II transcription subunit 6;Mediator of RNA polymerase II transcription subunit 7;Nuclear receptor coactivator 1,GO:0005634;GO:0006355;GO:0009299;GO:0016592,nucleus;regulation of DNA-templated transcription;mRNA transcription;mediator complex,cellular_component;biological_process;biological_process;cellular_component,ENSP00000428982;ENSP00000370938;ENSP00000263253;ENSP00000405330;ENSP00000300651;ENSP00000255764;ENSP00000363193;ENSP00000380888;ENSP00000323720;ENSP00000325612;ENSP00000251871;ENSP00000265350;ENSP00000282892;ENSP00000357047;ENSP00000440100;ENSP00000481920;ENSP00000286317;ENSP00000385216,0,0,0,0
7598,CAV1-ESR1-VDAC1 complex,19595769,CAV1;ESR1;VDAC1,Caveolin-1;Estrogen receptor;Non-selective voltage-gated ion channel VDAC1,GO:0005886;GO:0008308,plasma membrane;voltage-gated monoatomic anion channel activity,cellular_component;molecular_function,ENSP00000339191;ENSP00000405330;ENSP00000378487,22,22,0,0
7609,ADA-ADORA2A-DPP4 complex,29497379,ADA;ADORA2A;DPP4,Adenosine deaminase;Adenosine receptor A2a;Dipeptidyl peptidase 4,GO:0001973;GO:0007186;GO:0035589;GO:0043063;GO:0098609,G protein-coupled adenosine receptor signaling pathway;G protein-coupled receptor signaling pathway;G protein-coupled purinergic nucleotide receptor signaling pathway;intercellular bridge organization;cell-cell adhesion,biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000361965;ENSP00000480012;ENSP00000353731,1,1,0,0
7612,LIM protein complex LHX3-TGFB1I1-ISL1,28139974,ISL1;LHX3;TGFB1I1,Insulin gene enhancer protein ISL-1;LIM/homeobox protein Lhx3;Transforming growth factor beta-1-induced transcript 1 protein,GO:0007601,visual perception,biological_process,ENSP00000230658;ENSP00000360811;ENSP00000378332,0,0,0,0
7613,MN-hexamer complex,23798382,ISL1;LHX3;STAT3,Insulin gene enhancer protein ISL-1;LIM/homeobox protein Lhx3;Signal transducer and activator of transcription 3,GO:0021522;GO:0045944,spinal cord motor neuron differentiation;positive regulation of transcription by RNA polymerase II,biological_process;biological_process,ENSP00000230658;ENSP00000360811;ENSP00000264657,0,0,0,0
7627,H2A.Z histone-exchange complex p400/TIP60,24463511,ACTL6A;ANP32E;BRD8;DMAP1;EP400;EPC1;EPC2;H2AZ1;H2BC4;H3C1;H4C1;ING3;IPO9;KAT5;MORF4L1;MORF4L2;MRGBP;PRKDC;RUVBL1;RUVBL2;SRCAP;TRRAP;VPS72;XRCC5;XRCC6;YEATS4;ZNHIT1,Actin-like protein 6A;Acidic leucine-rich nuclear phosphoprotein 32 family member E;Bromodomain-containing protein 8;DNA methyltransferase 1-associated protein 1;E1A-binding protein p400;Enhancer of polycomb homolog 1;Enhancer of polycomb homolog 2;Histone H2A.Z;Histone H2B type 1-C/E/F/G/I;Histone H3.1;Histone H4;Inhibitor of growth protein 3;Importin-9;Histone acetyltransferase KAT5;Mortality factor 4-like protein 1;Mortality factor 4-like protein 2;MRG/MORF4L-binding protein;DNA-dependent protein kinase catalytic subunit;RuvB-like 1;RuvB-like 2;Helicase SRCAP;Transformation/transcription domain-associated protein;Vacuolar protein sorting-associated protein 72 homolog;X-ray repair cross-complementing protein 5;X-ray repair cross-complementing protein 6;YEATS domain-containing protein 4;Zinc finger HIT domain-containing protein 1,GO:0003677;GO:0006338,DNA binding;chromatin remodeling,molecular_function;biological_process,ENSP00000397552;ENSP00000463154;ENSP00000254900;ENSP00000361363;ENSP00000374212;ENSP00000263062;ENSP00000258484;ENSP00000296417;ENSP00000289316;ENSP00000480826;ENSP00000481486;ENSP00000320566;ENSP00000354742;ENSP00000340330;ENSP00000331310;ENSP00000394417;ENSP00000359518;ENSP00000313420;ENSP00000318297;ENSP00000473172;ENSP00000262518;ENSP00000352925;ENSP00000346464;ENSP00000375978;ENSP00000352257;ENSP00000247843;ENSP00000304593,0,0,0,0
7673,ANKS1A-EPHA8-RINL complex,22291991,ANKS1A;EPHA8;RINL,Ankyrin repeat and SAM domain-containing protein 1A;Ephrin type-A receptor 8;Ras and Rab interactor-like protein,GO:0030163,protein catabolic process,biological_process,ENSP00000353518;ENSP00000166244;ENSP00000467107,0,0,0,0
7696,DONSON-MCM2-MCM7-PCNA-TICRR complex,28191891,DONSON;MCM2;MCM7;PCNA;TICRR,Protein downstream neighbor of Son;DNA replication licensing factor MCM2;DNA replication licensing factor MCM7;Proliferating cell nuclear antigen;Treslin,GO:0006260,DNA replication,biological_process,ENSP00000307143;ENSP00000265056;ENSP00000307288;ENSP00000368458;ENSP00000268138,0,0,0,0
7699,MCPH1-Condensin II complex,18718915,MCPH1;NCAPD3;NCAPG2;NCAPH2;SMC2;SMC4;TERF2;TERF2IP,Microcephalin;Condensin-2 complex subunit D3;Condensin-2 complex subunit G2;Condensin-2 complex subunit H2;Structural maintenance of chromosomes protein 2;Structural maintenance of chromosomes protein 4;Telomeric repeat-binding factor 2;Telomeric repeat-binding factor 2-interacting protein 1,GO:0000725;GO:0005634;GO:0030261;GO:1901990,recombinational repair;nucleus;chromosome condensation;regulation of mitotic cell cycle phase transition,biological_process;cellular_component;biological_process;biological_process,ENSP00000342924;ENSP00000433681;ENSP00000387007;ENSP00000299821;ENSP00000286398;ENSP00000341382;ENSP00000254942;ENSP00000300086,0,0,0,0
7724,GABBR1-GABBR2-GRM1 complex,31977183,GABBR1;GABBR2;GRM1,Gamma-aminobutyric acid type B receptor subunit 1;Gamma-aminobutyric acid type B receptor subunit 2;Metabotropic glutamate receptor 1,GO:0007186;GO:0007214;GO:0007216;GO:0007269,G protein-coupled receptor signaling pathway;gamma-aminobutyric acid signaling pathway;G protein-coupled glutamate receptor signaling pathway;neurotransmitter secretion,biological_process;biological_process;biological_process;biological_process,ENSP00000366233;ENSP00000259455;ENSP00000282753,74,74,74,0
7729,ADORA2A-CNR1-DRD2 complex,18587404,ADORA2A;CNR1;DRD2,Adenosine receptor A2a;Cannabinoid receptor 1;D(2) dopamine receptor,GO:0001973;GO:0007186;GO:0007212;GO:0035589;GO:0038171,G protein-coupled adenosine receptor signaling pathway;G protein-coupled receptor signaling pathway;G protein-coupled dopamine receptor signaling pathway;G protein-coupled purinergic nucleotide receptor signaling pathway;cannabinoid signaling pathway,biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000480012;ENSP00000358513;ENSP00000354859,22,22,0,0
7739,Intraflagellar transport complex A TULP3-IFT122-IFT140-IFT144 subcomplex,27932497,IFT122;IFT140;TULP3;WDR19,Intraflagellar transport protein 122 homolog;Intraflagellar transport protein 140 homolog;Tubby-related protein 3;WD repeat-containing protein 19,GO:0005929;GO:0035721;GO:0042073,cilium;intraciliary retrograde transport;intraciliary transport,cellular_component;biological_process;biological_process,ENSP00000296266;ENSP00000406012;ENSP00000380321;ENSP00000382717,0,0,0,0
7792,AXL-DOCK1-ELMO2-MET complex,30108175,AXL;DOCK1;ELMO2;MET,Tyrosine-protein kinase receptor UFO;Dedicator of cytokinesis protein 1;Engulfment and cell motility protein 2;Hepatocyte growth factor receptor,GO:0004713;GO:0005886;GO:0007010,protein tyrosine kinase activity;plasma membrane;cytoskeleton organization,molecular_function;cellular_component;biological_process,ENSP00000301178;ENSP00000485033;ENSP00000290246;ENSP00000317272,2,0,0,0
7813,CDYL-complex,19061646,CDYL;EHMT1;EHMT2;HDAC1;HDAC2;MIER1;REST;SETDB1;WIZ,Chromodomain Y-like protein;Histone-lysine N-methyltransferase EHMT1;Histone-lysine N-methyltransferase EHMT2;Histone deacetylase 1;Histone deacetylase 2;Mesoderm induction early response protein 1;RE1-silencing transcription factor;Histone-lysine N-methyltransferase SETDB1;Protein Wiz,GO:0005634;GO:0045892;GO:0140993,nucleus;negative regulation of DNA-templated transcription;histone modifying activity,cellular_component;biological_process;molecular_function,ENSP00000380718;ENSP00000417980;ENSP00000379078;ENSP00000362649;ENSP00000430432;ENSP00000383820;ENSP00000311816;ENSP00000271640;ENSP00000469534,0,0,0,0
7836,GOLGA2-PCDC10-STK26 complex,20332113,GOLGA2;PDCD10;STK26,Golgin subfamily A member 2;Programmed cell death protein 10;Serine/threonine-protein kinase 26,GO:0005794;GO:0016477;GO:0030011;GO:0051683,Golgi apparatus;cell migration;maintenance of cell polarity;establishment of Golgi localization,cellular_component;biological_process;biological_process;biological_process,ENSP00000416097;ENSP00000376506;ENSP00000377867,2,2,0,0
7862,NALCN-UNC79-UNC80 complex,21040849,NALCN;UNC79;UNC80,Sodium leak channel NALCN;Protein unc-79 homolog;Protein unc-80 homolog,GO:0005886;GO:0022840;GO:0035725,plasma membrane;leak channel activity;sodium ion transmembrane transport,cellular_component;molecular_function;biological_process,ENSP00000251127;ENSP00000256339;ENSP00000391088,104,104,0,0
7867,CFAP410-NEK1-SPATA7 complex,26167768,CFAP410;NEK1;SPATA7,Cilia- and flagella-associated protein 410;Serine/threonine-protein kinase Nek1;Spermatogenesis-associated protein 7,GO:0036064;GO:0060271,ciliary basal body;cilium assembly,cellular_component;biological_process,ENSP00000381047;ENSP00000424757;ENSP00000377176,0,0,0,0
7868,MMP9-NEU1-TLR7 complex,23827939,MMP9;NEU1;TLR7,Matrix metalloproteinase-9;Sialidase-1;Toll-like receptor 7,GO:0006954;GO:0008063,inflammatory response;Toll signaling pathway,biological_process;biological_process,ENSP00000361405;ENSP00000364782;ENSP00000370034,0,0,0,0
7934,GTF2I-PARP1-SFPQ complex,18445785,GTF2I;PARP1;SFPQ,"General transcription factor II-I;Poly [ADP-ribose] polymerase 1;Splicing factor, proline- and glutamine-rich",GO:0001764;GO:0003677;GO:0005634;GO:0006355;GO:0006357;GO:0009790,neuron migration;DNA binding;nucleus;regulation of DNA-templated transcription;regulation of transcription by RNA polymerase II;embryo development,biological_process;molecular_function;cellular_component;biological_process;biological_process;biological_process,ENSP00000460070;ENSP00000355759;ENSP00000349748,20,0,20,20
7944,TM4SF5-mTOR-SLC38A9 complex,30956113,MTOR;SLC38A9;TM4SF5,Serine/threonine-protein kinase mTOR;Neutral amino acid transporter 9;Transmembrane 4 L6 family member 5,GO:0005765;GO:0031929,lysosomal membrane;TOR signaling,cellular_component;biological_process,ENSP00000354558;ENSP00000380074;ENSP00000270560,0,0,0,0
7949,USH1G-USH2A-WHRN complex,28137943,USH1G;USH2A;WHRN,pre-mRNA splicing regulator USH1G;Usherin;Whirlin,GO:0007601;GO:0007605;GO:0032391;GO:0050953,visual perception;sensory perception of sound;photoreceptor connecting cilium;sensory perception of light stimulus,biological_process;biological_process;cellular_component;biological_process,ENSP00000480279;ENSP00000305941;ENSP00000354623,0,0,0,0
7980,ncBAF complex,1234567,ACTB;ACTL6A;BCL7A;BCL7C;BICRAL;BRD9;SMARCA2;SMARCC1;SMARCD1;SS18,"Actin, cytoplasmic 1;Actin-like protein 6A;B-cell CLL/lymphoma 7 protein family member A;B-cell CLL/lymphoma 7 protein family member C;BRD4-interacting chromatin-remodeling complex-associated protein-like;Bromodomain-containing protein 9;Probable global transcription activator SNF2L2;SWI/SNF complex subunit SMARCC1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;Protein SSXT",GO:0006338;GO:0006355;GO:0071565,chromatin remodeling;regulation of DNA-templated transcription;nBAF complex,biological_process;biological_process;cellular_component,ENSP00000494750;ENSP00000397552;ENSP00000445868;ENSP00000369674;ENSP00000313933;ENSP00000419765;ENSP00000371638;ENSP00000254480;ENSP00000378414;ENSP00000414516,0,0,0,0
7981,ncBAF complex,1234567,ACTB;ACTL6A;BCL7A;BCL7C;BICRAL;BRD9;SMARCA4;SMARCC1;SMARCD1;SS18,"Actin, cytoplasmic 1;Actin-like protein 6A;B-cell CLL/lymphoma 7 protein family member A;B-cell CLL/lymphoma 7 protein family member C;BRD4-interacting chromatin-remodeling complex-associated protein-like;Bromodomain-containing protein 9;Transcription activator BRG1;SWI/SNF complex subunit SMARCC1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;Protein SSXT",GO:0006338;GO:0006355;GO:0071565,chromatin remodeling;regulation of DNA-templated transcription;nBAF complex,biological_process;biological_process;cellular_component,ENSP00000494750;ENSP00000397552;ENSP00000445868;ENSP00000369674;ENSP00000313933;ENSP00000419765;ENSP00000343896;ENSP00000254480;ENSP00000378414;ENSP00000414516,0,0,0,0
7992,RNA polymerase III complex,33335104,CRCP;POLR1C;POLR1D;POLR2H;POLR2K;POLR2L;POLR3A;POLR3B;POLR3C;POLR3D;POLR3E;POLR3F;POLR3G;POLR3H;POLR3K,"DNA-directed RNA polymerase III subunit RPC9;DNA-directed RNA polymerases I and III subunit RPAC1;DNA-directed RNA polymerases I and III subunit RPAC2;DNA-directed RNA polymerases I, II, and III subunit RPABC3;DNA-directed RNA polymerases I, II, and III subunit RPABC4;DNA-directed RNA polymerases I, II, and III subunit RPABC5;DNA-directed RNA polymerase III subunit RPC1;DNA-directed RNA polymerase III subunit RPC2;DNA-directed RNA polymerase III subunit RPC3;DNA-directed RNA polymerase III subunit RPC4;DNA-directed RNA polymerase III subunit RPC5;DNA-directed RNA polymerase III subunit RPC6;DNA-directed RNA polymerase III subunit RPC7;DNA-directed RNA polymerase III subunit RPC8;DNA-directed RNA polymerase III subunit RPC10",GO:0006383;GO:0006384;GO:0006386,transcription by RNA polymerase III;transcription initiation at RNA polymerase III promoter;termination of RNA polymerase III transcription,biological_process;biological_process;biological_process,ENSP00000378736;ENSP00000496044;ENSP00000302478;ENSP00000415536;ENSP00000342889;ENSP00000324124;ENSP00000361446;ENSP00000228347;ENSP00000334564;ENSP00000380904;ENSP00000299853;ENSP00000366828;ENSP00000498469;ENSP00000347345;ENSP00000293860,0,0,0,0
8014,TULP3-Intraflagellar transport complex A,24563533,IFT122;IFT140;IFT43;TTC21B;TULP3;WDR19;WDR35,Intraflagellar transport protein 122 homolog;Intraflagellar transport protein 140 homolog;Intraflagellar transport protein 43 homolog;Tetratricopeptide repeat protein 21B;Tubby-related protein 3;WD repeat-containing protein 19;WD repeat-containing protein 35,GO:0005929;GO:0035720;GO:0042073,cilium;intraciliary anterograde transport;intraciliary transport,cellular_component;biological_process;biological_process,ENSP00000296266;ENSP00000406012;ENSP00000238628;ENSP00000243344;ENSP00000380321;ENSP00000382717;ENSP00000314444,0,0,0,0
8056,ATR-ATRIP-TIM complex,15798197,ATR;ATRIP;TIMELESS,Serine/threonine-protein kinase ATR;ATR-interacting protein;Protein timeless homolog,GO:0007623,circadian rhythm,biological_process,ENSP00000343741;ENSP00000323099;ENSP00000450607,0,0,0,0
8074,ARL3-RP2-UNC119 complex,18588884,ARL3;RP2;UNC119,ADP-ribosylation factor-like protein 3;Protein XRP2;Protein unc-119 homolog A,GO:0003924;GO:0007601;GO:0009881;GO:0097733,GTPase activity;visual perception;photoreceptor activity;photoreceptor cell cilium,molecular_function;biological_process;molecular_function;cellular_component,ENSP00000260746;ENSP00000218340;ENSP00000337040,0,0,0,0
8075,PARL-STOML2-YME1L1 complex,27737933,PARL;STOML2;YME1L1,"Presenilin-associated rhomboid-like protein, mitochondrial;Stomatin-like protein 2, mitochondrial;ATP-dependent zinc metalloprotease YME1L1",GO:0005739;GO:0034982;GO:0035694,mitochondrion;mitochondrial protein processing;mitochondrial protein catabolic process,cellular_component;biological_process;biological_process,ENSP00000325421;ENSP00000348886;ENSP00000318480,0,0,0,0
8099,NIPBL-RAD21-SMC1A complex,34315879,NIPBL;RAD21;SMC1A,Nipped-B-like protein;Double-strand-break repair protein rad21 homolog;Structural maintenance of chromosomes protein 1A,GO:0000785,chromatin,cellular_component,ENSP00000282516;ENSP00000297338;ENSP00000323421,5,5,5,5
8115,IL-6 receptor-IL-6 complex,2788034,IL6;IL6R;IL6ST,Interleukin-6;Interleukin-6 receptor subunit alpha;Interleukin-6 receptor subunit beta,GO:0006953;GO:0006955;GO:0019221;GO:0031347;GO:0070102;GO:0070741,acute-phase response;immune response;cytokine-mediated signaling pathway;regulation of defense response;interleukin-6-mediated signaling pathway;response to interleukin-6,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000385675;ENSP00000357470;ENSP00000370698,0,0,0,0
8135,PLAT-PLG-THBS1 complex,3160707,PLAT;PLG;THBS1,Tissue-type plasminogen activator;Plasminogen;Thrombospondin-1,GO:0010756,positive regulation of plasminogen activation,biological_process,ENSP00000220809;ENSP00000308938;ENSP00000260356,3,3,0,0
8136,HRG-PLAT-PLG complex,3160707,HRG;PLAT;PLG,Histidine-rich glycoprotein;Tissue-type plasminogen activator;Plasminogen,GO:0010756,positive regulation of plasminogen activation,biological_process,ENSP00000232003;ENSP00000220809;ENSP00000308938,0,0,0,0
8142,CLC-CLF-CNTFR complex,10966616,CLCF1;CNTFR;CRLF1,Cardiotrophin-like cytokine factor 1;Ciliary neurotrophic factor receptor subunit alpha;Cytokine receptor-like factor 1,GO:0019221;GO:0048666,cytokine-mediated signaling pathway;neuron development,biological_process;biological_process,ENSP00000309338;ENSP00000368265;ENSP00000376188,0,0,0,0
8175,AKAP9-PDE4D-PRKACA complex,22908311,AKAP9;PDE4D;PRKACA,"A-kinase anchor protein 9;3',5'-cyclic-AMP phosphodiesterase 4D;cAMP-dependent protein kinase catalytic subunit alpha",GO:0004115;GO:0004691;GO:0005813;GO:0043949,"3',5'-cyclic-AMP phosphodiesterase activity;cAMP-dependent protein kinase activity;centrosome;regulation of cAMP-mediated signaling",molecular_function;molecular_function;cellular_component;biological_process,ENSP00000348573;ENSP00000345502;ENSP00000309591,0,0,0,0
8211,ACK1-GRB2-ALK complex,19815557,ALK;GRB2;TNK2,ALK tyrosine kinase receptor;Growth factor receptor-bound protein 2;Activated CDC42 kinase 1,GO:0045859,regulation of protein kinase activity,biological_process,ENSP00000373700;ENSP00000376345;ENSP00000371341,5,5,0,0
8214,MIG6-GRB2-PDGFR complex,19815557,ERRFI1;GRB2;PDGFRA,ERBB receptor feedback inhibitor 1;Growth factor receptor-bound protein 2;Platelet-derived growth factor receptor alpha,GO:0045859,regulation of protein kinase activity,biological_process,ENSP00000366702;ENSP00000376345;ENSP00000257290,2,2,0,0
8216,ALK-GRB2-MIG6 complex,19815557,ALK;ERRFI1;GRB2,ALK tyrosine kinase receptor;ERBB receptor feedback inhibitor 1;Growth factor receptor-bound protein 2,GO:0045859,regulation of protein kinase activity,biological_process,ENSP00000373700;ENSP00000366702;ENSP00000376345,4,4,0,0
8253,DCTN1-OSBPL1A-RAB7A-RILP complex,19564404,DCTN1;OSBPL1A;RAB7A;RILP,Dynactin subunit 1;Oxysterol-binding protein-related protein 1;Ras-related protein Rab-7a;Rab-interacting lysosomal protein,GO:0005770;GO:0043231,late endosome;intracellular membrane-bounded organelle,cellular_component;cellular_component,ENSP00000354791;ENSP00000320291;ENSP00000265062;ENSP00000301336,1,0,0,0
8301,AIPL1 chaperone complex,18408180,AIPL1;HSP90AA1;HSPA1A;HSPA8,Aryl-hydrocarbon-interacting protein-like 1;Heat shock protein HSP 90-alpha;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein,GO:0007601;GO:0061077,visual perception;chaperone-mediated protein folding,biological_process;biological_process,ENSP00000370521;ENSP00000335153;ENSP00000364802;ENSP00000437125,0,0,0,0
8303,GRIN1-GRIN2B-PRR7 complex,27458189,GRIN1;GRIN2B;PRR7,"Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2B;Proline-rich protein 7",GO:0004972;GO:0048167,NMDA glutamate receptor activity;regulation of synaptic plasticity,molecular_function;biological_process,ENSP00000360608;ENSP00000477455;ENSP00000327168,0,0,0,0
8310,mTORC1-PRAS40 complex,17604271,AKT1S1;MLST8;MTOR;RPTOR,Proline-rich AKT1 substrate 1;Target of rapamycin complex subunit LST8;Serine/threonine-protein kinase mTOR;Regulatory-associated protein of mTOR,GO:0001558;GO:0005764;GO:0006468;GO:0031931;GO:0032869;GO:0038202;GO:0042127;GO:0051726;GO:0071230,regulation of cell growth;lysosome;protein phosphorylation;TORC1 complex;cellular response to insulin stimulus;TORC1 signaling;regulation of cell population proliferation;regulation of cell cycle;cellular response to amino acid stimulus,biological_process;cellular_component;biological_process;cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000375711;ENSP00000457870;ENSP00000354558;ENSP00000307272,0,0,0,0
8317,AKT1-CDC37-CDK4-HSPA1A-HSP90AA1-NR3C1-PPP5C-RAF1-TSC1-TSC2 complex,29127155,CDC37;HSP90AA1;HSPA1A;PPP5C;TSC1;TSC2,Hsp90 co-chaperone Cdc37;Heat shock protein HSP 90-alpha;Heat shock 70 kDa protein 1A;Serine/threonine-protein phosphatase 5;Hamartin;Tuberin,,,,ENSP00000222005;ENSP00000335153;ENSP00000364802;ENSP00000012443;ENSP00000298552;ENSP00000219476,0,0,0,0
8318,HSP90AA1-TSC1-TSC2 complex,29127155,HSP90AA1;TSC1;TSC2,Heat shock protein HSP 90-alpha;Hamartin;Tuberin,,,,ENSP00000335153;ENSP00000298552;ENSP00000219476,7,7,0,7
8335,GNAI1-GNB1-GNGT1-NTS-NTSR1 complex,33633398,GNAI1;GNB1;GNGT1;NTS;NTSR1,Guanine nucleotide-binding protein G(i) subunit alpha-1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(T) subunit gamma-T1;Neurotensin/neuromedin N;Neurotensin receptor type 1,GO:0007186;GO:0016492,G protein-coupled receptor signaling pathway;G protein-coupled neurotensin receptor activity,biological_process;molecular_function,ENSP00000497260;ENSP00000367872;ENSP00000248572;ENSP00000256010;ENSP00000359532,0,0,0,0
8336,CAV1-OCLN-PDCD6IP complex,33058236,CAV1;OCLN;PDCD6IP,Caveolin-1;Occludin;Programmed cell death 6-interacting protein,GO:1903900,regulation of viral life cycle,biological_process,ENSP00000339191;ENSP00000347379;ENSP00000411825,5,0,0,0
8355,AP2-PICALM adaptor complex,24067654,AP2A1;AP2B1;AP2M1;PICALM,AP-2 complex subunit alpha-1;AP-2 complex subunit beta;AP-2 complex subunit mu;Phosphatidylinositol-binding clathrin assembly protein,GO:0006914;GO:0030119;GO:0038024;GO:0072583,autophagy;AP-type membrane coat adaptor complex;cargo receptor activity;clathrin-dependent endocytosis,biological_process;cellular_component;molecular_function;biological_process,ENSP00000351926;ENSP00000483185;ENSP00000403362;ENSP00000377015,0,0,0,0
8357,DNAJB1-HSPA4-HSPA8 complex,26300264,DNAJB1;HSPA4;HSPA8,DnaJ homolog subfamily B member 1;Heat shock 70 kDa protein 4;Heat shock cognate 71 kDa protein,GO:0022411,cellular component disassembly,biological_process,ENSP00000254322;ENSP00000302961;ENSP00000437125,0,0,0,0
8382,PRC1.3a complex,22325352,AUTS2;CSNK2A1;CSNK2A2;CSNK2B;FBRS;FBRSL1;PCGF3;RING1;RNF2;RYBP,Autism susceptibility gene 2 protein;Casein kinase II subunit alpha;Casein kinase II subunit alpha';Casein kinase II subunit beta;Probable fibrosin-1;Fibrosin-1-like protein;Polycomb group RING finger protein 3;E3 ubiquitin-protein ligase RING1;E3 ubiquitin-protein ligase RING2;RING1 and YY1-binding protein,GO:0006355;GO:0035102,regulation of DNA-templated transcription;PRC1 complex,biological_process;cellular_component,ENSP00000344087;ENSP00000217244;ENSP00000262506;ENSP00000365042;ENSP00000348489;ENSP00000396160;ENSP00000354724;ENSP00000363787;ENSP00000356480;ENSP00000419494,0,0,0,0
8383,PRC1.3b complex,22325352,AUTS2;CSNK2A1;CSNK2A2;CSNK2B;FBRS;FBRSL1;PCGF3;RING1;RNF2;YAF2,Autism susceptibility gene 2 protein;Casein kinase II subunit alpha;Casein kinase II subunit alpha';Casein kinase II subunit beta;Probable fibrosin-1;Fibrosin-1-like protein;Polycomb group RING finger protein 3;E3 ubiquitin-protein ligase RING1;E3 ubiquitin-protein ligase RING2;YY1-associated factor 2,GO:0006355;GO:0035102,regulation of DNA-templated transcription;PRC1 complex,biological_process;cellular_component,ENSP00000344087;ENSP00000217244;ENSP00000262506;ENSP00000365042;ENSP00000348489;ENSP00000396160;ENSP00000354724;ENSP00000363787;ENSP00000356480;ENSP00000328004,0,0,0,0
8387,PRC1.5a complex,22325352,AUTS2;CSNK2A1;CSNK2A2;CSNK2B;FBRS;FBRSL1;PCGF5;RING1;RNF2;RYBP,Autism susceptibility gene 2 protein;Casein kinase II subunit alpha;Casein kinase II subunit alpha';Casein kinase II subunit beta;Probable fibrosin-1;Fibrosin-1-like protein;Polycomb group RING finger protein 5;E3 ubiquitin-protein ligase RING1;E3 ubiquitin-protein ligase RING2;RING1 and YY1-binding protein,GO:0006355;GO:0035102,regulation of DNA-templated transcription;PRC1 complex,biological_process;cellular_component,ENSP00000344087;ENSP00000217244;ENSP00000262506;ENSP00000365042;ENSP00000348489;ENSP00000396160;ENSP00000337500;ENSP00000363787;ENSP00000356480;ENSP00000419494,0,0,0,0
8388,PRC1.5c,22325352,AUTS2;CSNK2A1;CSNK2A2;CSNK2B;FBRS;FBRSL1;PCGF5;RING1;RNF2;YAF2,Autism susceptibility gene 2 protein;Casein kinase II subunit alpha;Casein kinase II subunit alpha';Casein kinase II subunit beta;Probable fibrosin-1;Fibrosin-1-like protein;Polycomb group RING finger protein 5;E3 ubiquitin-protein ligase RING1;E3 ubiquitin-protein ligase RING2;YY1-associated factor 2,GO:0006355;GO:0035102,regulation of DNA-templated transcription;PRC1 complex,biological_process;cellular_component,ENSP00000344087;ENSP00000217244;ENSP00000262506;ENSP00000365042;ENSP00000348489;ENSP00000396160;ENSP00000337500;ENSP00000363787;ENSP00000356480;ENSP00000328004,0,0,0,0
8396,GNB5-GPR179-RGS6 complex,22689652,GNB5;GPR179;RGS6,Guanine nucleotide-binding protein subunit beta-5;Probable G-protein coupled receptor 179;Regulator of G-protein signaling 6,GO:0005886;GO:0007186;GO:0007601;GO:1990603,plasma membrane;G protein-coupled receptor signaling pathway;visual perception;dark adaptation,cellular_component;biological_process;biological_process;biological_process,ENSP00000261837;ENSP00000483469;ENSP00000451030,0,0,0,0
8397,GNB5-GPR179-RGS7 complex,22689652,GNB5;GPR179;RGS7,Guanine nucleotide-binding protein subunit beta-5;Probable G-protein coupled receptor 179;Regulator of G-protein signaling 7,GO:0005886;GO:0007186;GO:0007601;GO:1990603,plasma membrane;G protein-coupled receptor signaling pathway;visual perception;dark adaptation,cellular_component;biological_process;biological_process;biological_process,ENSP00000261837;ENSP00000483469;ENSP00000355523,0,0,0,0
8398,GNB5-GPR179-RGS9 complex,22689652,GNB5;GPR179;RGS9,Guanine nucleotide-binding protein subunit beta-5;Probable G-protein coupled receptor 179;Regulator of G-protein signaling 9,GO:0005886;GO:0007186;GO:0007601;GO:1990603,plasma membrane;G protein-coupled receptor signaling pathway;visual perception;dark adaptation,cellular_component;biological_process;biological_process;biological_process,ENSP00000261837;ENSP00000483469;ENSP00000262406,0,0,0,0
8399,GNB5-GPR179-RGS11 complex,22689652,GNB5;GPR179;RGS11,Guanine nucleotide-binding protein subunit beta-5;Probable G-protein coupled receptor 179;Regulator of G-protein signaling 11,GO:0005886;GO:0007186;GO:0007601;GO:1990603,plasma membrane;G protein-coupled receptor signaling pathway;visual perception;dark adaptation,cellular_component;biological_process;biological_process;biological_process,ENSP00000261837;ENSP00000483469;ENSP00000380876,0,0,0,0
8407,TCTEX1 Ca2+ channel complex,15768038,CACNA1A;CACNA1B;DYNLT1,Voltage-dependent P/Q-type calcium channel subunit alpha-1A;Voltage-dependent N-type calcium channel subunit alpha-1B;Dynein light chain Tctex-type 1,GO:0005216;GO:0006812;GO:0008324,monoatomic ion channel activity;monoatomic cation transport;monoatomic cation transmembrane transporter activity,molecular_function;biological_process;molecular_function,ENSP00000489829;ENSP00000360423;ENSP00000356056,0,0,0,0
8432,CD36-TLR4-TLR6 complex,20037584,CD36;TLR4;TLR6,Platelet glycoprotein 4;Toll-like receptor 4;Toll-like receptor 6,GO:0001540;GO:0002221;GO:0002224;GO:0002755;GO:0006952;GO:0030169;GO:0032732;GO:0035666;GO:0045087;GO:0050729;GO:0051092;GO:0140052,amyloid-beta binding;pattern recognition receptor signaling pathway;toll-like receptor signaling pathway;MyD88-dependent toll-like receptor signaling pathway;defense response;low-density lipoprotein particle binding;positive regulation of interleukin-1 production;TRIF-dependent toll-like receptor signaling pathway;innate immune response;positive regulation of inflammatory response;positive regulation of NF-kappaB transcription factor activity;cellular response to oxidised low-density lipoprotein particle stimulus,molecular_function;biological_process;biological_process;biological_process;biological_process;molecular_function;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000415743;ENSP00000363089;ENSP00000389600,0,0,0,0
8453,NOTCH1-RBPJ-SBNO1 complex,28401892,NOTCH1;RBPJ;SBNO1,Neurogenic locus notch homolog protein 1;Recombining binding protein suppressor of hairless;Protein strawberry notch homolog 1,GO:0009790,embryo development,biological_process,ENSP00000498587;ENSP00000345206;ENSP00000473665,0,0,0,0
8470,Distal appendage,29789620,C2CD3;CBY1;CCP110;CEP162;CEP164;CEP290;CEP83;CEP89;CEP97;FBF1;ODF2;SCLT1,C2 domain-containing protein 3;Protein chibby homolog 1;Centriolar coiled-coil protein of 110 kDa;Centrosomal protein of 162 kDa;Centrosomal protein of 164 kDa;Centrosomal protein of 290 kDa;Centrosomal protein of 83 kDa;Centrosomal protein of 89 kDa;Centrosomal protein of 97 kDa;Fas-binding factor 1;Outer dense fiber protein 2;Sodium channel and clathrin linker 1,GO:0060271;GO:0097539,cilium assembly;ciliary transition fiber,biological_process;cellular_component,ENSP00000334379;ENSP00000478962;ENSP00000370803;ENSP00000385215;ENSP00000278935;ENSP00000448012;ENSP00000380911;ENSP00000306105;ENSP00000342510;ENSP00000490726;ENSP00000403453;ENSP00000281142,0,0,0,0
8533,"SNARE complex (SNAP23, STX4, VAMP8)",12130530,SNAP23;STX4;VAMP8,Synaptosomal-associated protein 23;Syntaxin-4;Vesicle-associated membrane protein 8,GO:0006906;GO:0016079;GO:0031201;GO:0048489;GO:0061025,vesicle fusion;synaptic vesicle exocytosis;SNARE complex;synaptic vesicle transport;membrane fusion,biological_process;biological_process;cellular_component;biological_process;biological_process,ENSP00000249647;ENSP00000317714;ENSP00000263864,0,0,0,0
8569,"MITRAC complex, mitochondrial",23260140,CMC1;COA1;COA3;COX14;COX15;COX16;COX4I1;COX5A;COX6C;MT-CO1;MT-CO2;MT-CO3;SURF1;TIMM21,"COX assembly mitochondrial protein homolog;Cytochrome c oxidase assembly factor 1 homolog;Cytochrome c oxidase assembly factor 3 homolog, mitochondrial;Cytochrome c oxidase assembly protein COX14;Heme A synthase COX15;Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial;Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;Cytochrome c oxidase subunit 5A, mitochondrial;Cytochrome c oxidase subunit 6C;Cytochrome c oxidase subunit 1;Cytochrome c oxidase subunit 2;Cytochrome c oxidase subunit 3;Surfeit locus protein 1;Mitochondrial import inner membrane translocase subunit Tim21",GO:0005739;GO:0022904;GO:0032543;GO:0033108;GO:0033617;GO:0098798,mitochondrion;respiratory electron transport chain;mitochondrial translation;mitochondrial respiratory chain complex assembly;mitochondrial cytochrome c oxidase assembly;mitochondrial protein-containing complex,cellular_component;biological_process;biological_process;biological_process;biological_process;cellular_component,ENSP00000418348;ENSP00000379218;ENSP00000354762;ENSP00000326052;ENSP00000016171;ENSP00000374562;ENSP00000457513;ENSP00000317780;ENSP00000429707;ENSP00000354499;ENSP00000354876;ENSP00000354982;ENSP00000361042;ENSP00000169551,0,0,0,0
8597,KPNB1-SMN1-SNUPN-ZRP1 complex,12095920,KPNB1;SMN1;SNUPN;ZPR1,Importin subunit beta-1;Survival motor neuron protein;Snurportin-1;Zinc finger protein ZPR1,GO:0005634;GO:0005737;GO:0006404,nucleus;cytoplasm;RNA import into nucleus,cellular_component;cellular_component;biological_process,ENSP00000290158;ENSP00000370119;ENSP00000454852;ENSP00000227322,0,0,0,0
8607,CXCR4-GDF5-HSPA8-HSP90AA1 complex,11276205,CXCR4;GDF5;HSP90AA1;HSPA8,C-X-C chemokine receptor type 4;Growth/differentiation factor 5;Heat shock protein HSP 90-alpha;Heat shock cognate 71 kDa protein,GO:0001530;GO:0007165;GO:0007186;GO:0070098,lipopolysaccharide binding;signal transduction;G protein-coupled receptor signaling pathway;chemokine-mediated signaling pathway,molecular_function;biological_process;biological_process;biological_process,ENSP00000386884;ENSP00000363492;ENSP00000335153;ENSP00000437125,1,0,0,0
8620,IL1R1-IL1RAP-IRAK2 complex,23264670,IL1R1;IL1RAP;IRAK2,Interleukin-1 receptor type 1;Interleukin-1 receptor accessory protein;Interleukin-1 receptor-associated kinase-like 2,GO:0006952;GO:0006955;GO:0019221;GO:0050727;GO:0051092;GO:0070498,defense response;immune response;cytokine-mediated signaling pathway;regulation of inflammatory response;positive regulation of NF-kappaB transcription factor activity;interleukin-1-mediated signaling pathway,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000386380;ENSP00000314807;ENSP00000256458,3,3,0,3
8621,IL1R1-IL1RAP-IRAK1-MYD88 complex,23264669,IL1R1;IL1RAP;IRAK1;MYD88,Interleukin-1 receptor type 1;Interleukin-1 receptor accessory protein;Interleukin-1 receptor-associated kinase 1;Myeloid differentiation primary response protein MyD88,GO:0006952;GO:0006955;GO:0019221;GO:0045087;GO:0050727;GO:0051092;GO:0070498;GO:0070555,defense response;immune response;cytokine-mediated signaling pathway;innate immune response;regulation of inflammatory response;positive regulation of NF-kappaB transcription factor activity;interleukin-1-mediated signaling pathway;response to interleukin-1,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000386380;ENSP00000314807;ENSP00000358997;ENSP00000498321,0,0,0,0
8649,GRB2-MED28-NF2 complex,15467741,GRB2;MED28;NF2,Growth factor receptor-bound protein 2;Mediator of RNA polymerase II transcription subunit 28;Merlin,GO:0005856;GO:0007166,cytoskeleton;cell surface receptor signaling pathway,cellular_component;biological_process,ENSP00000376345;ENSP00000237380;ENSP00000344666,0,0,0,0
8658,ATG2B-TRAPPC11-WDR45 complex,30843302,ATG2B;TRAPPC11;WDR45,Autophagy-related protein 2 homolog B;Trafficking protein particle complex subunit 11;WD repeat domain phosphoinositide-interacting protein 4,GO:1905146,lysosomal protein catabolic process,biological_process,ENSP00000353010;ENSP00000335371;ENSP00000348848,0,0,0,0
8677,TLR3-associated signaling complex,23449395,CASP8;CFLAR;CFLAR;FADD;RIPK1;TICAM1;TLR3,Caspase-8;CASP8 and FADD-like apoptosis regulator;CASP8 and FADD-like apoptosis regulator;FAS-associated death domain protein;Receptor-interacting serine/threonine-protein kinase 1;TIR domain-containing adapter molecule 1;Toll-like receptor 3,GO:0002221;GO:0002224;GO:0034138;GO:0042981;GO:0045087;GO:0051607,pattern recognition receptor signaling pathway;toll-like receptor signaling pathway;toll-like receptor 3 signaling pathway;regulation of apoptotic process;innate immune response;defense response to virus,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000351273;ENSP00000312455;ENSP00000301838;ENSP00000259808;ENSP00000248244;ENSP00000296795,0,0,0,0
8678,TLR3 death-signaling complex,22421964,CASP10;CASP8;CFLAR;FADD;RIPK1;TICAM1;TLR3,Caspase-10;Caspase-8;CASP8 and FADD-like apoptosis regulator;FAS-associated death domain protein;Receptor-interacting serine/threonine-protein kinase 1;TIR domain-containing adapter molecule 1;Toll-like receptor 3,GO:0002221;GO:0002224;GO:0006952;GO:0034138;GO:0043065;GO:0043331;GO:0045087,pattern recognition receptor signaling pathway;toll-like receptor signaling pathway;defense response;toll-like receptor 3 signaling pathway;positive regulation of apoptotic process;response to dsRNA;innate immune response,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000286186;ENSP00000351273;ENSP00000312455;ENSP00000301838;ENSP00000259808;ENSP00000248244;ENSP00000296795,0,0,0,0
8712,HDAC2-MYCN-SP1 complex,20697349,HDAC2;MYCN;SP1,Histone deacetylase 2;N-myc proto-oncogene protein;Transcription factor Sp1,GO:0005634;GO:0045892,nucleus;negative regulation of DNA-templated transcription,cellular_component;biological_process,ENSP00000430432;ENSP00000281043;ENSP00000329357,0,0,0,0
8713,HDAC1-MYCN-SP1 complex,18003922,HDAC1;MYCN;SP1,Histone deacetylase 1;N-myc proto-oncogene protein;Transcription factor Sp1,GO:0005634;GO:0045892,nucleus;negative regulation of DNA-templated transcription,cellular_component;biological_process,ENSP00000362649;ENSP00000281043;ENSP00000329357,5,5,5,5
8757,MYCN-SP1-ZBTB17 complex,21123453,MYCN;SP1;ZBTB17,N-myc proto-oncogene protein;Transcription factor Sp1;Zinc finger and BTB domain-containing protein 17,GO:0005634;GO:0045892,nucleus;negative regulation of DNA-templated transcription,cellular_component;biological_process,ENSP00000281043;ENSP00000329357;ENSP00000364885,0,0,0,0
8762,HYAL2-SMAD3-WWOX complex,27845895,HYAL2;SMAD3;WWOX,Hyaluronidase-2;Mothers against decapentaplegic homolog 3;WW domain-containing oxidoreductase,,,,ENSP00000401853;ENSP00000332973;ENSP00000457230,0,0,0,0
8867,ITGA4-ITGAB7-VCAM1 complex,1372909,ITGA4;ITGB7;VCAM1,Integrin alpha-4;Integrin beta-7;Vascular cell adhesion protein 1,GO:0007155;GO:0008305,cell adhesion;integrin complex,biological_process;cellular_component,ENSP00000380227;ENSP00000267082;ENSP00000294728,4,4,0,0
8890,NCOR2-RXRA-THRB complex,7566127,NCOR2;RXRA;THRB,Nuclear receptor corepressor 2;Retinoic acid receptor RXR-alpha;Thyroid hormone receptor beta,GO:0005634;GO:0009755;GO:0045892;GO:0071300;GO:0097067,nucleus;hormone-mediated signaling pathway;negative regulation of DNA-templated transcription;cellular response to retinoic acid;cellular response to thyroid hormone stimulus,cellular_component;biological_process;biological_process;biological_process;biological_process,ENSP00000384018;ENSP00000419692;ENSP00000379904,70,70,0,0
8965,KCNA3-KCNA4-KCNA1-KCNA2 complex,10428084,KCNA1;KCNA2;KCNA3;KCNA4,Potassium voltage-gated channel subfamily A member 1;Potassium voltage-gated channel subfamily A member 2;Potassium voltage-gated channel subfamily A member 3;Potassium voltage-gated channel subfamily A member 4,GO:0005249;GO:0006813;GO:0008076;GO:0071805,voltage-gated potassium channel activity;potassium ion transport;voltage-gated potassium channel complex;potassium ion transmembrane transport,molecular_function;biological_process;cellular_component;biological_process,ENSP00000371985;ENSP00000487785;ENSP00000358784;ENSP00000328511,0,0,0,0
8980,"NMDA receptor complex (GRIN1, GRIN2A, GRIN2C) heterotetramer",36309015,GRIN1;GRIN2A;GRIN2C,"Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2A;Glutamate receptor ionotropic, NMDA 2C",GO:0004972;GO:0051262;GO:0098989,NMDA glutamate receptor activity;protein tetramerization;NMDA selective glutamate receptor signaling pathway,molecular_function;biological_process;biological_process,ENSP00000360608;ENSP00000332549;ENSP00000293190,20,20,0,0
9009,APP695-GRIN1-GRIN2A complex,22450047,APP;GRIN1;GRIN2A,"Amyloid-beta precursor protein;Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2A",GO:0004972;GO:0005783,NMDA glutamate receptor activity;endoplasmic reticulum,molecular_function;cellular_component,ENSP00000284981;ENSP00000360608;ENSP00000332549,118,118,0,0
9010,APP695-GRIN1-GRIN2B complex,22450047,APP;GRIN1;GRIN2B,"Amyloid-beta precursor protein;Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2B",GO:0004972;GO:0005783,NMDA glutamate receptor activity;endoplasmic reticulum,molecular_function;cellular_component,ENSP00000284981;ENSP00000360608;ENSP00000477455,143,143,0,0
9029,APP695-GRIN1-GRIN2A-NETO1 complex,23621516,APP;GRIN1;GRIN2A;NETO1,"Amyloid-beta precursor protein;Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2A;Neuropilin and tolloid-like protein 1",GO:0004972;GO:2000310,NMDA glutamate receptor activity;regulation of NMDA receptor activity,molecular_function;biological_process,ENSP00000284981;ENSP00000360608;ENSP00000332549;ENSP00000313088,0,0,0,0
9030,APP695-GRIN1-GRIN2B-NETO1 complex,23621516,APP;GRIN1;GRIN2B;NETO1,"Amyloid-beta precursor protein;Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2B;Neuropilin and tolloid-like protein 1",GO:0004972;GO:2000310,NMDA glutamate receptor activity;regulation of NMDA receptor activity,molecular_function;biological_process,ENSP00000284981;ENSP00000360608;ENSP00000477455;ENSP00000313088,0,0,0,0
9056,KCNA5-KCNAB1-RACK1 complex,22547057,KCNA5;KCNAB1;PRKCB;PRKCQ;RACK1,Potassium voltage-gated channel subfamily A member 5;Voltage-gated potassium channel subunit beta-1;Protein kinase C beta type;Protein kinase C theta type;Small ribosomal subunit protein RACK1,GO:0090036,regulation of protein kinase C signaling,biological_process,ENSP00000252321;ENSP00000419952;ENSP00000496129;ENSP00000263125;ENSP00000426909,0,0,0,0
9069,GRIK1-GRIK2-GRIK3 complex,10493729,GRIK1;GRIK2;GRIK3,"Glutamate receptor ionotropic, kainate 1;Glutamate receptor ionotropic, kainate 2;Glutamate receptor ionotropic, kainate 3",GO:0004970;GO:0015277;GO:0032983,glutamate-gated receptor activity;kainate selective glutamate receptor activity;kainate selective glutamate receptor complex,molecular_function;molecular_function;cellular_component,ENSP00000327687;ENSP00000397026;ENSP00000362183,0,0,0,0
9086,IL-1 receptor-IL-1B complex,22426547,IL1B;IL1R1;IL1RAP,Interleukin-1 beta;Interleukin-1 receptor type 1;Interleukin-1 receptor accessory protein,GO:0004908;GO:0006952;GO:0006955;GO:0019221;GO:0034097;GO:0050727;GO:0051092;GO:0070498;GO:0070555,interleukin-1 receptor activity;defense response;immune response;cytokine-mediated signaling pathway;response to cytokine;regulation of inflammatory response;positive regulation of NF-kappaB transcription factor activity;interleukin-1-mediated signaling pathway;response to interleukin-1,molecular_function;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000263341;ENSP00000386380;ENSP00000314807,0,0,0,0
9266,"AIPL1-PDE6 (PDE6A, PDE6B, PDE6G) complex",31488544,AIPL1;PDE6A;PDE6B;PDE6G,"Aryl-hydrocarbon-interacting protein-like 1;Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha;Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta;Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma",GO:0007601;GO:0007602;GO:0009881;GO:0047555,"visual perception;phototransduction;photoreceptor activity;3',5'-cyclic-GMP phosphodiesterase activity",biological_process;biological_process;molecular_function;molecular_function,ENSP00000370521;ENSP00000255266;ENSP00000420295;ENSP00000328412,0,0,0,0
9270,"AIPL1-PDE6 (PDE6C, PDE6H) complex",31488544,AIPL1;PDE6C;PDE6H,"Aryl-hydrocarbon-interacting protein-like 1;Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha';Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma",GO:0007601;GO:0007602;GO:0009881;GO:0047555,"visual perception;phototransduction;photoreceptor activity;3',5'-cyclic-GMP phosphodiesterase activity",biological_process;biological_process;molecular_function;molecular_function,ENSP00000370521;ENSP00000360502;ENSP00000266395,0,0,0,0
9309,KCNQ2-KCNQ3-KCNE2 complex,11034315,KCNE2;KCNQ2;KCNQ3,Potassium voltage-gated channel subfamily E member 2;Potassium voltage-gated channel subfamily KQT member 2;Potassium voltage-gated channel subfamily KQT member 3,GO:0071805,potassium ion transmembrane transport,biological_process,ENSP00000290310;ENSP00000352035;ENSP00000373648,5,0,0,0
9364,DLG3-DLG4-PTK2B complex,12576483,DLG3;DLG4;PTK2B,Disks large homolog 3;Disks large homolog 4;Protein-tyrosine kinase 2-beta,GO:0043197;GO:0097119;GO:1900271,dendritic spine;postsynaptic density protein 95 clustering;regulation of long-term synaptic potentiation,cellular_component;biological_process;biological_process,ENSP00000363480;ENSP00000497806;ENSP00000380638,23,23,23,0
9637,GNAS-GNB1-GNG2-SCT-SCTR complex,32811827,GNAS;GNB1;GNG2;SCT;SCTR,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Secretin;Secretin receptor,GO:0002024;GO:0007186;GO:0042593;GO:0060259,diet induced thermogenesis;G protein-coupled receptor signaling pathway;glucose homeostasis;regulation of feeding behavior,biological_process;biological_process;biological_process;biological_process,ENSP00000360141;ENSP00000367872;ENSP00000334448;ENSP00000176195;ENSP00000019103,0,0,0,0
9690,Adrenomedullin 2-CALCRL-RAMP1 complex,30139742,ADM2;CALCRL;RAMP1,Protein ADM2;Calcitonin gene-related peptide type 1 receptor;Receptor activity-modifying protein 1,GO:0007186;GO:0042311;GO:1990410,G protein-coupled receptor signaling pathway;vasodilation;adrenomedullin receptor signaling pathway,biological_process;biological_process;biological_process,ENSP00000379087;ENSP00000376177;ENSP00000254661,0,0,0,0
9706,NCOR2-THRB-TRIP4 complex,10454579,NCOR2;THRB;TRIP4,Nuclear receptor corepressor 2;Thyroid hormone receptor beta;Activating signal cointegrator 1,GO:0005634;GO:0045893;GO:0097067,nucleus;positive regulation of DNA-templated transcription;cellular response to thyroid hormone stimulus,cellular_component;biological_process;biological_process,ENSP00000384018;ENSP00000379904;ENSP00000261884,53,53,0,0
9854,CALCA-CALCRL-Gs-RAMP1 complex,30209400,CALCA;CALCRL;GNAS;GNB1;GNG2;RAMP1,Calcitonin gene-related peptide 1;Calcitonin gene-related peptide type 1 receptor;Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Receptor activity-modifying protein 1,GO:0007186;GO:0007218,G protein-coupled receptor signaling pathway;neuropeptide signaling pathway,biological_process;biological_process,ENSP00000331746;ENSP00000376177;ENSP00000360141;ENSP00000367872;ENSP00000334448;ENSP00000254661,0,0,0,0
9858,Adrenomedullin-CALCRL-Gs-RAMP3 complex,32296767,ADM;CALCRL;GNAS;GNB1;GNG2;RAMP3,Pro-adrenomedullin;Calcitonin gene-related peptide type 1 receptor;Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Receptor activity-modifying protein 3,GO:0001525;GO:0001666;GO:0001944;GO:0006979;GO:0007186;GO:0007566;GO:0042311,angiogenesis;response to hypoxia;vasculature development;response to oxidative stress;G protein-coupled receptor signaling pathway;embryo implantation;vasodilation,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000436607;ENSP00000376177;ENSP00000360141;ENSP00000367872;ENSP00000334448;ENSP00000242249,2,2,0,0
9948,CACNA1B-CACNA2D1-CACNB3 complex,34234349,CACNA1B;CACNA2D1;CACNB3,Voltage-dependent N-type calcium channel subunit alpha-1B;Voltage-dependent calcium channel subunit alpha-2/delta-1;Voltage-dependent L-type calcium channel subunit beta-3,GO:0005245;GO:0098703,voltage-gated calcium channel activity;calcium ion import across plasma membrane,molecular_function;biological_process,ENSP00000360423;ENSP00000349320;ENSP00000301050,96,96,96,0
10101,"Adenosine A1 receptor-Gi complex, adenosine-bound",29925945,ADORA1;GNAI2;GNB1;GNG2,Adenosine receptor A1;Guanine nucleotide-binding protein G(i) subunit alpha-2;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,GO:0001973;GO:0007186;GO:0035589,G protein-coupled adenosine receptor signaling pathway;G protein-coupled receptor signaling pathway;G protein-coupled purinergic nucleotide receptor signaling pathway,biological_process;biological_process;biological_process,ENSP00000356205;ENSP00000312999;ENSP00000367872;ENSP00000334448,0,0,0,0
10133,DDC-PI3K complex,30796964,DDC;PIK3CA;PIK3R1,"Aromatic-L-amino-acid decarboxylase;Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform;Phosphatidylinositol 3-kinase regulatory subunit alpha",GO:0008283,cell population proliferation,biological_process,ENSP00000403644;ENSP00000263967;ENSP00000428056,2,0,0,0
10162,"ADORA2B-SNAP23-VAMP2 complex, adenosine-stimulated",15256361,ADORA2B;SNAP23;VAMP2,Adenosine receptor A2b;Synaptosomal-associated protein 23;Vesicle-associated membrane protein 2,GO:0001973;GO:0007186;GO:0035589,G protein-coupled adenosine receptor signaling pathway;G protein-coupled receptor signaling pathway;G protein-coupled purinergic nucleotide receptor signaling pathway,biological_process;biological_process;biological_process,ENSP00000304501;ENSP00000249647;ENSP00000418572,0,0,0,0
10196,ACKR3-AVPR1A-CXCR4 complex,34032285,ACKR3;AVPR1A;CXCR4,Atypical chemokine receptor 3;Vasopressin V1a receptor;C-X-C chemokine receptor type 4,GO:0007186;GO:0070098,G protein-coupled receptor signaling pathway;chemokine-mediated signaling pathway,biological_process;biological_process,ENSP00000272928;ENSP00000299178;ENSP00000386884,0,0,0,0
10197,ACKR3-ADRA1A-AVPR1A complex,34032285,ACKR3;ADRA1A;AVPR1A,Atypical chemokine receptor 3;Alpha-1A adrenergic receptor;Vasopressin V1a receptor,GO:0007186;GO:0071875,G protein-coupled receptor signaling pathway;adrenergic receptor signaling pathway,biological_process;biological_process,ENSP00000272928;ENSP00000369960;ENSP00000299178,0,0,0,0
10281,GDF15-GFRAL-RET complex ,28846099,GDF15;GFRAL;RET,Growth/differentiation factor 15;GDNF family receptor alpha-like;Proto-oncogene tyrosine-protein kinase receptor Ret,GO:0002023;GO:0032095;GO:0160144,reduction of food intake in response to dietary excess;regulation of response to food;GDF15-GFRAL signaling pathway,biological_process;biological_process;biological_process,ENSP00000252809;ENSP00000343636;ENSP00000347942,1,1,0,0
10293,GDNF-GFRA1-SORL1 complex,23333276,GDNF;GFRA1;SORL1,Glial cell line-derived neurotrophic factor;GDNF family receptor alpha-1;Sortilin-related receptor,GO:0006622;GO:0030971;GO:0031547,protein targeting to lysosome;receptor tyrosine kinase binding;brain-derived neurotrophic factor receptor signaling pathway,biological_process;molecular_function;biological_process,ENSP00000409007;ENSP00000347591;ENSP00000260197,20,20,0,0
10295,GFRA1-RET-SORL1 complex,23333276,GFRA1;RET;SORL1,GDNF family receptor alpha-1;Proto-oncogene tyrosine-protein kinase receptor Ret;Sortilin-related receptor,GO:0006622;GO:0031547,protein targeting to lysosome;brain-derived neurotrophic factor receptor signaling pathway,biological_process;biological_process,ENSP00000347591;ENSP00000347942;ENSP00000260197,51,51,0,0
10323,GDNF-GFRA1-RET complex,8674117,GDNF;GFRA1;RET,Glial cell line-derived neurotrophic factor;GDNF family receptor alpha-1;Proto-oncogene tyrosine-protein kinase receptor Ret,GO:0004713;GO:0007399;GO:0035860;GO:0038023,protein tyrosine kinase activity;nervous system development;glial cell-derived neurotrophic factor receptor signaling pathway;signaling receptor activity,molecular_function;biological_process;biological_process;molecular_function,ENSP00000409007;ENSP00000347591;ENSP00000347942,30,30,0,0
10324,GFRA2-NRTN-RET complex,31392261,GFRA2;NRTN;RET,GDNF family receptor alpha-2;Neurturin;Proto-oncogene tyrosine-protein kinase receptor Ret,GO:0004713;GO:0007399;GO:0016167;GO:0038023,protein tyrosine kinase activity;nervous system development;glial cell-derived neurotrophic factor receptor activity;signaling receptor activity,molecular_function;biological_process;molecular_function;molecular_function,ENSP00000428518;ENSP00000302648;ENSP00000347942,0,0,0,0
10416,KDR-NRP1-PLXND1 complex,20434998,KDR;NRP1;PLXND1,Vascular endothelial growth factor receptor 2;Neuropilin-1;Plexin-D1,GO:0017154;GO:0031175;GO:0048010;GO:0061564,semaphorin receptor activity;neuron projection development;vascular endothelial growth factor receptor signaling pathway;axon development,molecular_function;biological_process;biological_process;biological_process,ENSP00000263923;ENSP00000265371;ENSP00000317128,19,19,0,0
10472,FGF13-SCN8A-SCN1B complex,36696443,FGF13;SCN1B;SCN8A,Fibroblast growth factor 13;Sodium channel regulatory subunit beta-1;Sodium channel protein type 8 subunit alpha,GO:0002028;GO:0017080,regulation of sodium ion transport;sodium channel regulator activity,biological_process;molecular_function,ENSP00000396198;ENSP00000396915;ENSP00000346534,0,0,0,0
10478,SCN9A-SCN1B-SCN2B complex,30765606,SCN1B;SCN2B;SCN9A,Sodium channel regulatory subunit beta-1;Sodium channel regulatory subunit beta-2;Sodium channel protein type 9 subunit alpha,GO:0002028;GO:0005248;GO:0017080;GO:0035725,regulation of sodium ion transport;voltage-gated sodium channel activity;sodium channel regulator activity;sodium ion transmembrane transport,biological_process;molecular_function;molecular_function;biological_process,ENSP00000396915;ENSP00000278947;ENSP00000386306,59,59,0,0
10486,ATP1A3-ATP1B1-FXYD6 complex,36075933,ATP1A3;ATP1B1;FXYD6,Sodium/potassium-transporting ATPase subunit alpha-3;Sodium/potassium-transporting ATPase subunit beta-1;FXYD domain-containing ion transport regulator 6,GO:0017080;GO:1902305,sodium channel regulator activity;regulation of sodium ion transmembrane transport,molecular_function;biological_process,ENSP00000444688;ENSP00000356790;ENSP00000442756,58,58,58,0
10503,ATP1A3-ATP1B2-RS1-SARM1 complex,17804407,ATP1A3;ATP1B2;RS1;SARM1,Sodium/potassium-transporting ATPase subunit alpha-3;Sodium/potassium-transporting ATPase subunit beta-2;Retinoschisin;NAD(+) hydrolase SARM1,GO:0001895;GO:0007601;GO:0045494;GO:0060342,retina homeostasis;visual perception;photoreceptor cell maintenance;photoreceptor inner segment membrane,biological_process;biological_process;biological_process;cellular_component,ENSP00000444688;ENSP00000250111;ENSP00000369320;ENSP00000468032,0,0,0,0
10517,CHRNA1-CHRNB1-CHRND-CHRNE-CHRNA7 complex,15609996,CHRNA1;CHRNA7;CHRNB1;CHRND;CHRNE,Acetylcholine receptor subunit alpha;Neuronal acetylcholine receptor subunit alpha-7;Acetylcholine receptor subunit beta;Acetylcholine receptor subunit delta;Acetylcholine receptor subunit epsilon,GO:0095500,acetylcholine receptor signaling pathway,biological_process,ENSP00000261007;ENSP00000299847;ENSP00000304290;ENSP00000258385;ENSP00000497829,0,0,0,0
10587,GABRA3-GABRB1-GABRE complex,16412217,GABRA3;GABRB1;GABRE,Gamma-aminobutyric acid receptor subunit alpha-3;Gamma-aminobutyric acid receptor subunit beta-1;Gamma-aminobutyric acid receptor subunit epsilon,GO:0004890;GO:0007214;GO:1902476,GABA-A receptor activity;gamma-aminobutyric acid signaling pathway;chloride transmembrane transport,molecular_function;biological_process;biological_process,ENSP00000359337;ENSP00000295454;ENSP00000359353,0,0,0,0
10609,GABRA3-GABRB1-GABRE-GABRQ complex,16412217,GABRA3;GABRB1;GABRE;GABRQ,Gamma-aminobutyric acid receptor subunit alpha-3;Gamma-aminobutyric acid receptor subunit beta-1;Gamma-aminobutyric acid receptor subunit epsilon;Gamma-aminobutyric acid receptor subunit theta,GO:0004890;GO:0007214;GO:1902476,GABA-A receptor activity;gamma-aminobutyric acid signaling pathway;chloride transmembrane transport,molecular_function;biological_process;biological_process,ENSP00000359337;ENSP00000295454;ENSP00000359353;ENSP00000469332,0,0,0,0
10731,CHRNA3-CHRNA5-CHRNB2 complex,8663494,CHRNA3;CHRNA5;CHRNB2,Neuronal acetylcholine receptor subunit alpha-3;Neuronal acetylcholine receptor subunit alpha-5;Neuronal acetylcholine receptor subunit beta-2,GO:0095500,acetylcholine receptor signaling pathway,biological_process,ENSP00000315602;ENSP00000299565;ENSP00000357461,0,0,0,0
10736,CHRNA3-CHRNA5-CHRNB4 complex ,8663494,CHRNA3;CHRNA5;CHRNB4,Neuronal acetylcholine receptor subunit alpha-3;Neuronal acetylcholine receptor subunit alpha-5;Neuronal acetylcholine receptor subunit beta-4,GO:0095500,acetylcholine receptor signaling pathway,biological_process,ENSP00000315602;ENSP00000299565;ENSP00000261751,0,0,0,0
10784,GNA12-GPR55-RGS2 complex,33092790,GNA12;GPR55;RGS2,Guanine nucleotide-binding protein subunit alpha-12;G-protein coupled receptor 55;Regulator of G-protein signaling 2,GO:0005886;GO:0007186;GO:0030334;GO:0038171;GO:0042127;GO:0055074;GO:0070372,plasma membrane;G protein-coupled receptor signaling pathway;regulation of cell migration;cannabinoid signaling pathway;regulation of cell population proliferation;calcium ion homeostasis;regulation of ERK1 and ERK2 cascade,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000275364;ENSP00000498258;ENSP00000235382,0,0,0,0
10785,GNAQ-GPR55-RGS2 complex,33092790,GNAQ;GPR55;RGS2,Guanine nucleotide-binding protein G(q) subunit alpha;G-protein coupled receptor 55;Regulator of G-protein signaling 2,GO:0005886;GO:0007186;GO:0030334;GO:0038171;GO:0042127;GO:0055074;GO:0070372,plasma membrane;G protein-coupled receptor signaling pathway;regulation of cell migration;cannabinoid signaling pathway;regulation of cell population proliferation;calcium ion homeostasis;regulation of ERK1 and ERK2 cascade,cellular_component;biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000286548;ENSP00000498258;ENSP00000235382,0,0,0,0
10801,DRD1-GRIN1-GRIN2B-HRH3 complex,27370794,DRD1;GRIN1;GRIN2B;HRH3,"D(1A) dopamine receptor;Glutamate receptor ionotropic, NMDA 1;Glutamate receptor ionotropic, NMDA 2B;Histamine H3 receptor",GO:0007186;GO:0007212;GO:0007215;GO:0070372;GO:0071420;GO:1990806,G protein-coupled receptor signaling pathway;G protein-coupled dopamine receptor signaling pathway;glutamate receptor signaling pathway;regulation of ERK1 and ERK2 cascade;cellular response to histamine;ligand-gated ion channel signaling pathway,biological_process;biological_process;biological_process;biological_process;biological_process;biological_process,ENSP00000377353;ENSP00000360608;ENSP00000477455;ENSP00000342560,0,0,0,0
11048,PPIA-PPP3CA-PPP3R1 complex,12218175,PPIA;PPP3CA;PPP3R1,Peptidyl-prolyl cis-trans isomerase A;Protein phosphatase 3 catalytic subunit alpha;Calcineurin subunit B type 1,GO:0045892;GO:0050868,negative regulation of DNA-templated transcription;negative regulation of T cell activation,biological_process;biological_process,ENSP00000419425;ENSP00000378323;ENSP00000234310,9,9,0,0
11162,GALR1-GPR39-HTR1A complex,26365466,GALR1;GPR39;HTR1A,Galanin receptor type 1;G-protein coupled receptor 39;5-hydroxytryptamine receptor 1A,GO:0007186;GO:0007210;GO:0042593;GO:0098664,G protein-coupled receptor signaling pathway;serotonin receptor signaling pathway;glucose homeostasis;G protein-coupled serotonin receptor signaling pathway,biological_process;biological_process;biological_process;biological_process,ENSP00000299727;ENSP00000327417;ENSP00000316244,0,0,0,0
11183,HEPH-SLC40A1-TF complex,37277838,HEPH;SLC40A1;TF,Hephaestin;Ferroportin;Serotransferrin,GO:0006826;GO:0060586,iron ion transport;multicellular organismal-level iron ion homeostasis,biological_process;biological_process,ENSP00000430620;ENSP00000261024;ENSP00000385834,0,0,0,0
11411,ACVR1-ACVR2A-INHBA complex,26621707,ACVR1;ACVR2A;INHBA,Activin receptor type-1;Activin receptor type-2A;Inhibin beta A chain,GO:0007179;GO:0032924,transforming growth factor beta receptor signaling pathway;activin receptor signaling pathway,biological_process;biological_process,ENSP00000405004;ENSP00000241416;ENSP00000242208,23,23,0,0
11412,ACVR1-ACVR2B-INHBA complex,26621707,ACVR1;ACVR2B;INHBA,Activin receptor type-1;Activin receptor type-2B;Inhibin beta A chain,GO:0007179;GO:0032924,transforming growth factor beta receptor signaling pathway;activin receptor signaling pathway,biological_process;biological_process,ENSP00000405004;ENSP00000340361;ENSP00000242208,5,5,0,0