Medical Action Ontology
type: Ontology
version IRI: maxo-base.owl
IAO_0000700: medical action
creator: Leigh Carmody
creator: Peter Robinson
description: An ontology to represent medically relevant actions, procedures, therapies, interventions, and recommendations.
type: IAO_8000001
license: https://creativecommons.org/licenses/by/4.0/
version info: 2026-01-15

avoided behavior
type: ObjectProperty
IAO_0000115: Refraining from performing, acting, or behaving some behavior.
date: 2020-01-28T19:01:13Z
creator: http://orcid.org/0000-0001-7941-2961

therapeutic uses
type: ObjectProperty
IAO_0000115: Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.
date: 2021-02-24T19:27:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D045506
has related synonym: drug uses
has related synonym: pharmocological uses

avoided medical action
type: ObjectProperty
IAO_0000115: Action of refraining from recommending, performing, or participating in some medical actions.
date: 2019-06-12T14:23:27Z
creator: http://orcid.org/0000-0001-7941-2961

avoided food
type: ObjectProperty
IAO_0000115: Refraining from consumption of some types of food.
date: 2019-07-12T14:23:27Z
creator: http://orcid.org/0000-0001-7941-2961

medical action
type: Class
subclass of: COB_0000082
IAO_0000115: A clinically prescribed procedure, therapy, intervention, or recommendation.
date: 2018-11-16T20:07:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: OGMS:0000096
has narrow synonym: health care process

Axiom
annotated source: medical action
annotated property: hasNarrowSynonym
annotated target: health care process
has db xref: OGMS:0000096

therapeutic procedure
type: Class
subclass of: medical action
IAO_0000115: All manners of treatment, be they pharmaceuticals, invasive procedures, etc. to relieve illness and injury in attempts to bring the body back to its normal state.
date: 2018-11-16T20:08:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C25218
has db xref: NCIT:C49236
has db xref: OAE:0000094
has db xref: OGMS:0000112
comment: An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process.

Axiom
annotated source: therapeutic procedure
annotated property: IAO_0000115
annotated target: All manners of treatment, be they pharmaceuticals, invasive procedures, etc. to relieve illness and injury in attempts to bring the body back to its normal state.
has db xref: ISBN-10:0124105165

Axiom
annotated source: therapeutic procedure
annotated property: comment
annotated target: An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process.
has db xref: NCIT:C49236

diagnostic procedure
type: Class
subclass of: medical action
IAO_0000115: Any procedure or test to diagnose a disease or disorder.
date: 2018-11-16T20:10:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C18020
has db xref: OGMS:0000104
has exact synonym: diagnostic technique procedure
has exact synonym: diagnostic testing

Axiom
annotated source: diagnostic procedure
annotated property: IAO_0000115
annotated target: Any procedure or test to diagnose a disease or disorder.
has db xref: NCIT:C18020

surgical procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery.
date: 2018-11-16T20:10:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: ERO:0000378
has db xref: NCIT:C15329
has db xref: NCIT:C17173
has db xref: NCRO:0000228
has db xref: OAE:0000067
has db xref: SCDO:1000017
has exact synonym: operation
has exact synonym: surgery
has exact synonym: surgical intervention
has exact synonym: surgical operation

Axiom
annotated source: surgical procedure
annotated property: IAO_0000115
annotated target: A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery.
has db xref: NCIT:C15329

clinical imaging procedure
type: Class
subclass of: diagnostic procedure
IAO_0000115: Any technology or method that aids in the visualization of any biological process, cell, tissue or organ for use in screening, diagnosis, surgical procedures or therapy.
date: 2018-11-16T20:10:50Z
has db xref: NCIT:C17369
has exact synonym: imaging procedure
has exact synonym: medical imaging
has narrow synonym: therapeutic imaging procedure
has narrow synonym: therapeutic imaging technique

Axiom
annotated source: clinical imaging procedure
annotated property: IAO_0000115
annotated target: Any technology or method that aids in the visualization of any biological process, cell, tissue or organ for use in screening, diagnosis, surgical procedures or therapy.
has db xref: NCIT:C17369

clinical laboratory procedure
type: Class
subclass of: diagnostic procedure
IAO_0000115: Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting for diagnosis, treatment, or therapy.
date: 2018-11-16T20:11:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C25294
has exact synonym: clinical lab testing
has exact synonym: clinical laboratory testing
has exact synonym: clinical testing
has exact synonym: lab testing

radiograph imaging with contrast dye
type: Class
equivalent class: Class
  intersection of: radiograph imaging procedure
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37334
subclass of: radiograph imaging procedure
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_37334
IAO_0000115: A test that involves the administration of contrast dye and X-ray imaging in order to be able to see soft tissue within the body. Dye can be added intravenously, ingested, or other methods.
date: 2023-02-22T20:05:27Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: radiographic imaging with contrast dye
has exact synonym: radiography with contrast dye

obsolete therapeutic intervention
type: Class
IAO_0100001: therapeutic procedure
deprecated: true

nutrition intervention
type: Class
subclass of: therapeutic procedure
IAO_0000115: Behavioral or regulatory nutritional interventions aim at modifying nutritional intake which have an impact on health outcomes.
date: 2018-11-16T20:12:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: nutritional intervention

Axiom
annotated source: nutrition intervention
annotated property: IAO_0000115
annotated target: Behavioral or regulatory nutritional interventions aim at modifying nutritional intake which have an impact on health outcomes.
has db xref: https://orcid.org/0000-0001-7941-2961

cognitive and behavioral intervention
type: Class
subclass of: therapy
IAO_0000115: Cognitive and behavioral interventions are therapies that are designed to decrease symptoms and foster the belief that one has control over thoughts, beliefs, attitudes, and skills to facilitate coping.
date: 2018-11-16T20:12:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116519
has db xref: NCIT:C15184
has db xref: NCIT:C64345
has exact synonym: cognitive and behavioral therapies
has exact synonym: cognitive and behavioral therapy
has exact synonym: cognitive and behavioural intervention
has exact synonym: cognitive behavior therapy
has exact synonym: cognitive behavioral therapy
has exact synonym: cognitive behaviour therapy
has exact synonym: cognitive behavioural therapy

Axiom
annotated source: cognitive and behavioral intervention
annotated property: IAO_0000115
annotated target: Cognitive and behavioral interventions are therapies that are designed to decrease symptoms and foster the belief that one has control over thoughts, beliefs, attitudes, and skills to facilitate coping.
has db xref: https://orcid.org/0000-0002-7463-6306
has db xref: PMID:22796302

physical therapy
type: Class
subclass of: therapy
IAO_0000115: The treatment of deformity or disease through mechanical force and movement, including both active and passive exercises, intended to ameliorate injury, increase mobility, and improve overall function.
date: 2018-11-16T20:12:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15302
has db xref: OGMS:0000115
has exact synonym: PT
has exact synonym: physiatric procedure
has exact synonym: physical medicine procedure
has exact synonym: physical therapeutics
has exact synonym: physical therapy procedure
has exact synonym: physiotherapy
has exact synonym: physiotherapy procedure

Axiom
annotated source: physical therapy
annotated property: IAO_0000115
annotated target: The treatment of deformity or disease through mechanical force and movement, including both active and passive exercises, intended to ameliorate injury, increase mobility, and improve overall function.
has db xref: NCIT:C15302

Axiom
annotated source: physical therapy
annotated property: hasExactSynonym
annotated target: PT
has synonym type: OMO_0003000

surgery by body site
type: Class
equivalent class: Class
  intersection of: surgical procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000467
subclass of: surgical procedure
subclass of: therapeutic procedure by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000467
IAO_0000115: A surgery performed on specific region of the body.
date: 2023-02-24T15:24:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: surgical procedure on body region

complementary and alternative medical therapy
type: Class
subclass of: medical action
IAO_0000115: Complementary and alternative medicine (CAM) or “complementary health approaches” are a group of diverse medical and health care practices and products that are not presently considered to be part of conventional medicine.
date: 2019-01-07T19:24:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51976
has db xref: SCDO:0000271
has exact synonym: CAM therapy
has exact synonym: complementary or alternative medical procedure
has narrow synonym: complementary medicine
has narrow synonym: complementary therapy

Axiom
annotated source: complementary and alternative medical therapy
annotated property: IAO_0000115
annotated target: Complementary and alternative medicine (CAM) or “complementary health approaches” are a group of diverse medical and health care practices and products that are not presently considered to be part of conventional medicine.
has db xref: NCCIH

radiation therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: Treatment of a disease by means of exposure of the target or the whole body to radiation. Radiation therapy is often used as part of curative therapy and occasionally as a component of palliative treatment for cancer. Other uses include total body irradiation prior to transplantation.
date: 2018-11-16T20:20:38Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15313
has db xref: OGMS:0000116
has exact synonym: RT
has exact synonym: radiation
has exact synonym: radiation therapy procedure
has exact synonym: radiotherapeutics
has exact synonym: radiotherapy

Axiom
annotated source: radiation therapy
annotated property: IAO_0000115
annotated target: Treatment of a disease by means of exposure of the target or the whole body to radiation. Radiation therapy is often used as part of curative therapy and occasionally as a component of palliative treatment for cancer. Other uses include total body irradiation prior to transplantation.
has db xref: NCIT:C15313

Axiom
annotated source: radiation therapy
annotated property: hasExactSynonym
annotated target: RT
has synonym type: OMO_0003000

biologic therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: A type of treatment that uses substances derived from or made by living organisms to treat disease; this includes both naturally occurring and synthetic products.
date: 2018-11-16T20:20:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15187
has exact synonym: BRM therapy
has exact synonym: biologic therapies
has exact synonym: biological response modifier therapy
has exact synonym: biological therapy
has exact synonym: biotheraphy

Axiom
annotated source: biologic therapy
annotated property: IAO_0000115
annotated target: A type of treatment that uses substances derived from or made by living organisms to treat disease; this includes both naturally occurring and synthetic products.
has db xref: NCIT:C15187

Axiom
annotated source: biologic therapy
annotated property: hasExactSynonym
annotated target: BRM therapy
has synonym type: OMO_0003000

cellular therapy
type: Class
subclass of: biologic therapy
IAO_0000115: Cell therapy is therapy in which cellular material is injected into a patient.
date: 2018-11-16T20:21:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C70601
has exact synonym: cell therapy
has exact synonym: cellular therapies

Axiom
annotated source: cellular therapy
annotated property: IAO_0000115
annotated target: Cell therapy is therapy in which cellular material is injected into a patient.
has db xref: PMID:24471045

preventative therapy
type: Class
subclass of: medical action
IAO_0000115: A therapy or action designed to prevent disease or ailment.
date: 2018-11-16T20:21:49Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: preventative clinical measure
has exact synonym: preventative medical action
has exact synonym: preventative therapeutics
has exact synonym: preventative therapies
has exact synonym: preventive medical action
has exact synonym: preventive medical measure

biomarker analysis
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: A broad subcategory of medical signs or objective indications of medical state which can be measured accurately and reproducibly.
date: 2018-11-16T20:22:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C63333
has exact synonym: biomarker assessment
has exact synonym: biomarker measurement
has exact synonym: biomarker test

Axiom
annotated source: biomarker analysis
annotated property: IAO_0000115
annotated target: A broad subcategory of medical signs or objective indications of medical state which can be measured accurately and reproducibly.
has db xref: PMID:20978388

esophography with contrast
type: Class
equivalent class: Class
  intersection of: radiograph imaging with contrast dye
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37334
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0001043
subclass of: radiograph imaging with contrast dye
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0001043
IAO_0000115: A radiographic examination of the esophagus in which the esophagusis made visible by barium or a water-soluble contrast administered orally prior to the examination.
date: 2023-02-22T20:53:16Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: contrast examination of the esophagus
has narrow synonym: barrium swallow test of the esophagus

behavioral preventative care
type: Class
subclass of: preventative therapy
IAO_0000115: A behavioral modification or implementation of a behavior designed to prevent disease or ailment.
date: 2018-11-16T20:22:48Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: behavioral preventative therapeutics
has exact synonym: behavioral preventive care
has exact synonym: behavioral preventive therapy
has exact synonym: preventative behavior therapy
has exact synonym: preventative behavioral therapy

palliative care
type: Class
subclass of: medical action
IAO_0000115: An approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial, and spiritual’.
date: 2018-11-16T20:23:01Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C101516
has db xref: NCIT:C15747
has exact synonym: comfort care
has exact synonym: palliative therapeutics
has exact synonym: symptom management
has narrow synonym: supportive care

Axiom
annotated source: palliative care
annotated property: IAO_0000115
annotated target: An approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial, and spiritual’.
has db xref: PMID:27162584

hospice care
type: Class
subclass of: end-of life care
IAO_0000115: A service delivery system that provides palliative care/medicine when life expectancy is 6 months or less and when curative or life-prolonging therapy is no longer indicated.
date: 2018-11-16T20:23:10Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15252

Axiom
annotated source: hospice care
annotated property: IAO_0000115
annotated target: A service delivery system that provides palliative care/medicine when life expectancy is 6 months or less and when curative or life-prolonging therapy is no longer indicated.
has db xref: PMID:22190887

mood and behavior-altering agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with an agent that can alter brain chemistry leading to mood and/or behaviorial changes.
date: 2023-02-23T18:26:42Z
creator: https://orcid.org/0000-0001-7941-2961
has narrow synonym: mood altering drug therapy

surgical procedure on the eye
type: Class
equivalent class: Class
  intersection of: surgery by body site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000019
subclass of: surgery by body site
subclass of: MAXO_0001397
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000019
IAO_0000115: Any surgical procedure conducted on the camera-type eye.
date: 2023-02-24T15:25:58Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: camera-type eye surgical procedure
has exact synonym: eye procedure
has exact synonym: eye surgery
has exact synonym: surgery of the eye

end-of life care
type: Class
subclass of: palliative care
IAO_0000115: Care for patients with a progressive life-limiting disease with a prognosis of months or less.
date: 2019-01-09T20:15:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C67359
has exact synonym: end-of-life treatment management

Axiom
annotated source: end-of life care
annotated property: IAO_0000115
annotated target: Care for patients with a progressive life-limiting disease with a prognosis of months or less.
has db xref: PMID:23796586

diathermy
type: Class
subclass of: therapeutic procedure
IAO_0000115: The production of heat in a body part by high-frequency electrical currents to stimulate circulation, relieve pain, cauterization, or destroy tissue.
date: 2023-03-02T20:01:36Z
creator: https://orcid.org/0000-0001-7941-2961

microwave diathermy
type: Class
subclass of: diathermy
IAO_0000115: A therapy using microwaves to focus on and heat up tissue with high water content, such as muscle.
date: 2023-03-02T20:08:03Z
creator: https://orcid.org/0000-0001-7941-2961

ultrasound therapy
type: Class
subclass of: diathermy
IAO_0000115: A deep heating modality that uses high-frequency acoustic vibrations within body tissues for the treatment of certain medical conditions, such as the alleviation of pain, muscle spasms, and joint contractures.
date: 2023-03-02T20:08:31Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: therapeutic ultrasound
has exact synonym: therapeutic ultrasound diathermy
has exact synonym: ultrasound diathermy therapy

cell measurement
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: Quantification of cell characteristics, including morphological or physiological parameter of one or more cells in order to determine the health of the patient and/or detect disease.
date: 2023-03-03T21:22:53Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: clinical cell assessment
has exact synonym: clinical cell measurement
has exact synonym: clinical cell test

short wave diathermy
type: Class
subclass of: diathermy
IAO_0000115: A form of deep heat therapy can induce vasodilatation, elevation of pain threshold, reduction in muscle spasm, acceleration of cellular metabolism, increased soft tissue extensibility, increase blood flow, decrease joint pain and stiffness, reduce inflammation, faster resolution of edema, and accelerate wound healing.
date: 2023-03-02T20:15:39Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: SWD
has exact synonym: radio-frequency diathermy
has exact synonym: short-wave diathermy
has exact synonym: shortwave diathermy
has narrow synonym: radio frequency heating

Axiom
annotated source: short wave diathermy
annotated property: IAO_0000115
annotated target: A form of deep heat therapy can induce vasodilatation, elevation of pain threshold, reduction in muscle spasm, acceleration of cellular metabolism, increased soft tissue extensibility, increase blood flow, decrease joint pain and stiffness, reduce inflammation, faster resolution of edema, and accelerate wound healing.
has db xref: PMID:31748973

life support care
type: Class
subclass of: end-of life care
IAO_0000115: Any medical procedure used to sustain the life of a patient in critical condition.
date: 2019-01-09T20:25:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C95171
has db xref: OMIT:0009105

Axiom
annotated source: life support care
annotated property: IAO_0000115
annotated target: Any medical procedure used to sustain the life of a patient in critical condition.
has db xref: NCIT:C95171

obsolete therapeutic avoidance of behavior
type: Class
IAO_0100001: cognitive and behavioral intervention avoidance
deprecated: true

cell morphology assessment
type: Class
subclass of: cell measurement
IAO_0000115: A measurement of the shape, structure, form, and size of cells from a patient to determine if there is disease and/or infection.
date: 2023-03-03T21:25:21Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: morphology evaluation

therapeutic procedure by site
type: Class
equivalent class: Class
  intersection of: therapeutic procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: therapeutic procedure
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001062
IAO_0000115: All manners of treatment to relieve illness and injury of a particular body site or system.
date: 2023-03-20T19:58:58Z
creator: https://orcid.org/0000-0001-7941-2961

obsolete therapeutic mental or psychological behavior avoidance
type: Class
IAO_0100001: cognitive and behavioral intervention avoidance
deprecated: true

obsolete stress avoidance
type: Class
IAO_0100001: MAXO_0002008
deprecated: true

obsolete smoking avoidance
type: Class
IAO_0100001: MAXO_0002002
deprecated: true

preventable disease avoidance recommendation
type: Class
subclass of: therapeutic avoidance intervention
IAO_0000115: A clinical recommendation to avoid preventable diseases by vaccination or otherwise lowering risk for certain diseases.
date: 2019-01-11T19:39:19Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: disease avoidance

communicable disease avoidance
type: Class
subclass of: preventable disease avoidance recommendation
IAO_0000115: Avoidance of an illness or infection that can be spread from person to person, animal to person, animal to animal or person to animal by taking precautionary measures, such as good hygiene practices or vaccines.
date: 2019-01-11T19:39:37Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: avoid communicable disease
has exact synonym: communicable disease prevention

obsolete physiologic state
type: Class
IAO_0100001: prevention of abnormal physiologic state
deprecated: true

dehydration prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Dehydration.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Dehydration avoidance
has exact synonym: avoid Dehydration recommendation

hypertension prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0000822
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Hypertension.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Hypertension avoidance
has exact synonym: avoid Hypertension recommendation

obesity prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001513
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Obesity.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Obesity avoidance
has exact synonym: avoid Obesity recommendation

inflammation of the skin prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0011123
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Inflammatory abnormality of the skin.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Inflammatory abnormality of the skin avoidance
has exact synonym: avoid Inflammatory abnormality of the skin recommendation

physical activity avoidance recommendation
type: Class
subclass of: physical therapy
subclass of: therapeutic avoidance intervention
IAO_0000115: Recommendation by a clinician to avoid exercise or physical activity.
date: 2019-01-11T20:11:57Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: avoid exercise
has exact synonym: avoidance of physical activity recommendation
has related synonym: rest recommendation
comment: avoidance of physical activity therapeutic recommendation

impact activities avoidance recommendation
type: Class
subclass of: physical activity avoidance recommendation
IAO_0000115: A recommendation by a clinician or therapist to avoid any impact activities to prevent medical issues or help the physical wellbeing of a patient.
date: 2019-01-11T20:12:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: impact sports avoidance
has exact synonym: therapeutic recommendation to avoid impact activities

isometric exercise avoidance recommendation
type: Class
subclass of: physical activity avoidance recommendation
IAO_0000115: A recommendation by a clinician or therapist to avoid isometric exercises to prevent medical issues or help the physical wellbeing of a patient.
date: 2019-01-11T20:13:10Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: therapeutic recommendation to avoid isometric exercise

therapeutic avoidance of environmental exposure
type: Class
subclass of: therapeutic avoidance intervention
IAO_0000115: A clinical recommendation to avoid or refrain from certain environmental exposures in order to maintain health or ameliorate symptoms.
date: 2019-01-11T20:50:37Z
creator: http://orcid.org/0000-0001-7941-2961

radiation exposure avoidance
type: Class
subclass of: therapeutic avoidance of environmental exposure
IAO_0000115: A clinical recommendation to avoid or refrain from unnecessary radiation exposure.
date: 2019-01-11T20:50:51Z
creator: http://orcid.org/0000-0001-7941-2961

sunlight avoidance
type: Class
subclass of: therapeutic avoidance of environmental exposure
IAO_0000115: A clinical recommendation to avoid or refrain from unnecessary sulight exposure.
date: 2019-01-11T20:56:19Z
creator: http://orcid.org/0000-0001-7941-2961

nutrition intake avoidance
type: Class
subclass of: nutrition intervention
IAO_0000115: A clinical recommendation to avoid the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.
date: 2019-01-11T20:56:39Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: food consumption avoidance

pharmacotherapy
type: Class
equivalent class: Class
  intersection of: therapeutic procedure
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_23888
subclass of: therapeutic procedure
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_23888
IAO_0000115: Use of a substance introduced into a living organism with therapeutic or diagnostic purpose.
date: 2019-01-15T18:20:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:52217
has exact synonym: drug treatment
has exact synonym: medication therapy
has exact synonym: pharmaceutical drug
has exact synonym: pharmaceutical treatment
has exact synonym: pharmacological treatment
comment: Medical treatment by means of drugs.

Axiom
annotated source: pharmacotherapy
annotated property: comment
annotated target: Medical treatment by means of drugs.
has db xref: https://orcid.org/0000-0001-7941-2961

antibacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_36047
subclass of: antimicrobial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_36047
IAO_0000115: Use of a drug to treat or prevent bacterial infections.
date: 2019-01-15T18:59:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:36047
has exact synonym: antibacterial treatment
has exact synonym: antibiotic agent therapy
has exact synonym: treatment with an anti-bacterial drug
has exact synonym: treatment with an anti-bacterial medication
has exact synonym: treatment with an anti-bacterial therapy
has exact synonym: treatment with an antibacterial agent
has exact synonym: treatment with an antibacterial drug
has exact synonym: treatment with an antibacterial medication
has exact synonym: treatment with an antibacterial therapy
has exact synonym: treatment with antibacterial drug

antineoplastic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35610
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35610
IAO_0000115: Use of a substance that inhibits or prevents the proliferation of neoplasms.
date: 2019-01-15T19:01:01Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: anticancer agent therapy
has db xref: CHEBI:35610
has db xref: NCIT:C274
has exact synonym: anti-neoplastic agent therapy
has exact synonym: antineoplastic drug therapy
has exact synonym: cytostatic agent therapy
has exact synonym: cytostatic drug therapy
has exact synonym: treatment with anti-cancer drug
has exact synonym: treatment with anti-cancer medication
has exact synonym: treatment with anti-neoplastic drug
has exact synonym: treatment with anti-neoplastic medication
has exact synonym: treatment with antineoplastic agent
has exact synonym: treatment with antineoplastic drug
has exact synonym: treatment with antineoplastic medication

aerobic exercise therapy
type: Class
subclass of: physical therapy
IAO_0000115: Sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body's use of oxygen.
date: 2019-01-15T19:02:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C39774
has exact synonym: aerobic activity
has exact synonym: aerobic exercise
comment: A medical recommendation of sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body's use of oxygen.

Axiom
annotated source: aerobic exercise therapy
annotated property: IAO_0000115
annotated target: Sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body's use of oxygen.
has db xref: NCIT:C39774

Axiom
annotated source: aerobic exercise therapy
annotated property: comment
annotated target: A medical recommendation of sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body's use of oxygen.
has db xref: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C39774

supplemental oxygen therapy
type: Class
subclass of: therapeutic procedure of respiratory system
IAO_0000115: The administration of oxygen to an individual, usually to aid in respiration.
date: 2019-01-15T19:14:17Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D010102
has db xref: NCIT:C94624
has exact synonym: oxygen inhalation therapy
has exact synonym: oxygen supplementation
has exact synonym: oxygen support therapy
comment: Inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (From Dorland, 27th ed & Stedman, 25th ed)

Axiom
annotated source: supplemental oxygen therapy
annotated property: IAO_0000115
annotated target: The administration of oxygen to an individual, usually to aid in respiration.
has db xref: NCIT:C94624

Axiom
annotated source: supplemental oxygen therapy
annotated property: comment
annotated target: Inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (From Dorland, 27th ed & Stedman, 25th ed)
has db xref: MeSH:D010102

lung volume reduction surgery
type: Class
subclass of: MAXO_0001514
IAO_0000115: A procedure designed to help you breathe easier when your lungs have been damaged by disease. The goal of the surgery is to remove the area of the lung most affected by disease, allowing the remaining lung to function more efficiently, and improve your breathing ability and quality of life.
date: 2019-01-15T19:14:42Z
creator: http://orcid.org/0000-0001-7941-2961

transplantation procedure
type: Class
subclass of: MAXO_0009026
IAO_0000115: Transference of a tissue or organ within an individual, between individuals of the same species, or between individuals of different species.
date: 2019-01-15T19:15:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15342
has db xref: NCIT:C15431
has db xref: OBI:0000105
has exact synonym: transplant procedure
has exact synonym: transplantation
has exact synonym: transplantation surgery
has exact synonym: transplantation surgical procedure
has narrow synonym: grafting procedure

Axiom
annotated source: transplantation procedure
annotated property: IAO_0000115
annotated target: Transference of a tissue or organ within an individual, between individuals of the same species, or between individuals of different species.
has db xref: NCIT:C15342

obsolete lung transplantation surgical procedure
type: Class
IAO_0100001: MAXO_0010038
deprecated: true

obsolete liver transplantation
type: Class
IAO_0100001: liver transplantation
has db xref: NCIT:C15271
has exact synonym: hepatic transplantation
has exact synonym: liver grafting
has exact synonym: liver transplantation
has exact synonym: surgical transplantation of the liver
deprecated: true

chemical exposure avoidance
type: Class
subclass of: therapeutic avoidance of environmental exposure
IAO_0000115: A clinical recommendation to avoid or refrain from unnecessary chemical exposure.
date: 2019-01-15T19:31:56Z
creator: http://orcid.org/0000-0001-7941-2961

ultrasonography procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: The use of ultrasound to produce images of structures in the human body.
date: 2019-01-15T19:32:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: ERO:0001325
has db xref: NCIT:C17230
has exact synonym: diagnostic ultrasound
has exact synonym: medical sonography
has exact synonym: sonography
has exact synonym: ultrasound procedure
comment: 2D ultrasounds produce a flat image of the organs. 3D images show three-dimensional external images of organs or fetus. 4D ultrasounds generates an image that is continuously updated, like amoving image.
comment: A procedure that uses high-energy sound waves to look at tissues and organs inside the body. The sound waves make echoes that form pictures of the tissues and organs on a computer screen (sonogram). Ultrasound may be used to help diagnose diseases, such as cancer. It may also be used during pregnancy to check the fetus (unborn baby) and during medical procedures, such as biopsies. Also called ultrasonography.

obsolete liver ultrasound procedure
type: Class
IAO_0100001: MAXO_0010204
deprecated: true

pancreatic function testing
type: Class
subclass of: digestive system testing
IAO_0000115: A procedure to measure pancreatic secretion to discriminate between pancreatic and nonpancreatic causes of malabsorption.
date: 2019-01-15T19:35:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C97101
has exact synonym: pancreatic function assessment

digestive system testing
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001007
subclass of: clinical chemistry assessment
subclass of: MAXO_0001396
IAO_0000115: The quantitative measurement of digestive system tests to diagnose or treat a digestive disorder using clinical laboratory procedures, imaging tests, endoscopic or other procedures.
date: 2019-01-15T19:35:36Z
creator: http://orcid.org/0000-0001-7941-2961

behavioral counseling
type: Class
subclass of: cognitive and behavioral intervention
IAO_0000115: The act of receiving professional guidance in resolving personal conflicts and emotional problems.
date: 2019-01-19T19:44:32Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15308
has db xref: NCIT:C61547
has exact synonym: NCIT:C63474
has exact synonym: behaviour therapy
has exact synonym: behavioural counseling
has exact synonym: counseling intervention
has narrow synonym: psychotherapy

Axiom
annotated source: behavioral counseling
annotated property: IAO_0000115
annotated target: The act of receiving professional guidance in resolving personal conflicts and emotional problems.
has db xref: NCIT:C61547

Axiom
annotated source: behavioral counseling
annotated property: hasExactSynonym
annotated target: counseling intervention
has db xref: NCIT:C61547

alcoholism counseling
type: Class
subclass of: behavioral counseling
IAO_0000115: Counseling designed to guide and support an individual to overcome alcohol dependence.
date: 2019-01-19T19:46:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C150658

Axiom
annotated source: alcoholism counseling
annotated property: IAO_0000115
annotated target: Counseling designed to guide and support an individual to overcome alcohol dependence.
has db xref: NCIT:C150658

genetic counseling
type: Class
subclass of: behavioral counseling
IAO_0000115: The process whereby an expert in hereditary disorders provides information about risk and clinical burden of a disorder or disorders to patients or relatives in families with genetic disorders as an aid to making informed and responsible decisions about marriage, children, early diagnosis, and handling disability.
date: 2019-01-19T19:48:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15240
has db xref: SCDO:0000443

Axiom
annotated source: genetic counseling
annotated property: IAO_0000115
annotated target: The process whereby an expert in hereditary disorders provides information about risk and clinical burden of a disorder or disorders to patients or relatives in families with genetic disorders as an aid to making informed and responsible decisions about marriage, children, early diagnosis, and handling disability.
has db xref: NCIT:C15240

stress management therapy
type: Class
subclass of: behavioral counseling
IAO_0000115: A wide range of techniques and psychotherapies aimed at controlling a person's level of stress.
date: 2019-01-19T19:49:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C67032
has exact synonym: therapy for stress
has exact synonym: therapy to relieve stress
has narrow synonym: stress management
has narrow synonym: stress therapy

tobacco cessation counseling
type: Class
subclass of: behavioral counseling
IAO_0000115: A process by which a health professional provides education, recommendations, or interventions to help clients stop using tobacco products. (ACC)
date: 2019-01-19T19:51:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C101244
has exact synonym: smoking cessation counseling
has narrow synonym: smoking cessation

Axiom
annotated source: tobacco cessation counseling
annotated property: IAO_0000115
annotated target: A process by which a health professional provides education, recommendations, or interventions to help clients stop using tobacco products. (ACC)
has db xref: NCIT:C101244

Axiom
annotated source: tobacco cessation counseling
annotated property: hasNarrowSynonym
annotated target: smoking cessation
has db xref: http://purl.obolibrary.org/obo/maxo.owl/https//orcid.org/0000-0001-7941-2961

acupuncture therapy
type: Class
subclass of: complementary and alternative medical therapy
IAO_0000115: The practice of piercing specific points on the body with very thin sterile needles in order to relieve pain or induce regional anesthesia.
date: 2019-01-19T20:30:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15176

Axiom
annotated source: acupuncture therapy
annotated property: IAO_0000115
annotated target: The practice of piercing specific points on the body with very thin sterile needles in order to relieve pain or induce regional anesthesia.
has db xref: NCIT:C15176

meditation therapy
type: Class
subclass of: complementary and alternative medical therapy
IAO_0000115: Continuous and profound contemplation or musing on a subject or series of subjects of a deep or abstruse nature; contemplation of spiritual matters
date: 2019-01-19T20:32:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51975
has db xref: SCDO:0000741

Axiom
annotated source: meditation therapy
annotated property: IAO_0000115
annotated target: Continuous and profound contemplation or musing on a subject or series of subjects of a deep or abstruse nature; contemplation of spiritual matters
has db xref: NCIT:C51975

yoga therapy
type: Class
subclass of: complementary and alternative medical therapy
IAO_0000115: An ancient system of practices used to balance the mind and body through exercise, meditation (focusing thoughts), and control of breathing and emotions. Yoga is being studied as a way to relieve stress and treat sleep problems.
date: 2019-01-19T20:34:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64897

Axiom
annotated source: yoga therapy
annotated property: IAO_0000115
annotated target: An ancient system of practices used to balance the mind and body through exercise, meditation (focusing thoughts), and control of breathing and emotions. Yoga is being studied as a way to relieve stress and treat sleep problems.
has db xref: NCIT:C64897

chiropractic therapy
type: Class
subclass of: complementary and alternative medical therapy
IAO_0000115: An alternative medical system that focuses on the relationship between bodily structure (primarily that of the spine) and function, and how that relationship affects the preservation and restoration of health. Chiropractors use manipulative therapy as an integral treatment tool.
date: 2019-01-19T20:35:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15204
has exact synonym: chiropractic therapies
has exact synonym: chiropractic treatment
has exact synonym: chiropratic medicine

Axiom
annotated source: chiropractic therapy
annotated property: IAO_0000115
annotated target: An alternative medical system that focuses on the relationship between bodily structure (primarily that of the spine) and function, and how that relationship affects the preservation and restoration of health. Chiropractors use manipulative therapy as an integral treatment tool.
has db xref: NCIT:C15204

massage therapy
type: Class
subclass of: complementary and alternative medical therapy
IAO_0000115: A therapeutic method of manipulation, methodical pressure, friction, and kneading of the body. (from Taber's)
date: 2019-01-19T20:36:55Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15276
has exact synonym: massage
has exact synonym: massage and body work

Axiom
annotated source: massage therapy
annotated property: IAO_0000115
annotated target: A therapeutic method of manipulation, methodical pressure, friction, and kneading of the body. (from Taber's)
has db xref: NCIT:C15276

dietary intervention
type: Class
subclass of: nutrition intervention
IAO_0000115: Any alteration or treatment in an individual's diet with a planned goal, usually designed to improve the individual's overall health.
date: 2019-01-19T20:39:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15447
has narrow synonym: diet
has related synonym: behavioral nutritional intervention

Axiom
annotated source: dietary intervention
annotated property: IAO_0000115
annotated target: Any alteration or treatment in an individual's diet with a planned goal, usually designed to improve the individual's overall health.
has db xref: NCIT:C15447

calorie restrictive diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: The restriction of energy (calorie) intake below the amount required for weight maintenance.
date: 2019-01-19T20:39:29Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: LCD intake
has exact synonym: calorie restricted food intake
has exact synonym: carorie restriction in food intake
has exact synonym: low calorie diet intake
has narrow synonym: primarily food‐based low‐calorie diet intake

Axiom
annotated source: calorie restrictive diet intake
annotated property: IAO_0000115
annotated target: The restriction of energy (calorie) intake below the amount required for weight maintenance.
has db xref: PMID:23748374

Axiom
annotated source: calorie restrictive diet intake
annotated property: hasExactSynonym
annotated target: LCD intake
has synonym type: OMO_0003000

enteral nutrition intake
type: Class
subclass of: nutrition intervention
IAO_0000115: Delivery of enteral nutrition via a tube placed into the stomach, duodenum, or jejunum.
date: 2019-01-19T20:40:39Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C93322
has exact synonym: EN intake
has exact synonym: enteral nutrition support intake
has exact synonym: enteral tube feeding nutrition intake
has exact synonym: tube feeding nutrition intake

Axiom
annotated source: enteral nutrition intake
annotated property: IAO_0000115
annotated target: Delivery of enteral nutrition via a tube placed into the stomach, duodenum, or jejunum.
has db xref: NCIT:C93322

Axiom
annotated source: enteral nutrition intake
annotated property: hasExactSynonym
annotated target: EN intake
has synonym type: OMO_0003000

obsolete alcohol intake avoidance
type: Class
IAO_0100001: MAXO_0010050
deprecated: true

excessive alcohol avoidance
type: Class
subclass of: MAXO_0010050
IAO_0000115: A medical requirement or recommendation of avoiding the consumption of large amounts of alcohol.
date: 2019-01-19T20:54:50Z
creator: http://orcid.org/0000-0001-7941-2961

estrogen-containing food avoidance
type: Class
subclass of: nutrition intake avoidance
IAO_0000115: A clinical recommendation to avoid foods with high concentrations of estrogen.
date: 2019-01-19T20:55:05Z
creator: http://orcid.org/0000-0001-7941-2961
comment: Some processed foods and soy contain large amounts of estrogen.

obsolete excessive iron consumption avoidance
type: Class
IAO_0100001: MAXO_0010100
deprecated: true

excessive protein consumption avoidance
type: Class
subclass of: MAXO_0010002
IAO_0000115: A clinical recomendation to avoid high-protein diets which may worsen kidney function.
date: 2019-01-19T21:00:36Z
creator: http://orcid.org/0000-0001-7941-2961

fasting avoidance
type: Class
subclass of: nutrition intervention
IAO_0000115: Clinical recommendation to avoid fasting due to health risks.
date: 2019-01-19T21:01:13Z
creator: http://orcid.org/0000-0001-7941-2961

fasting intervention
type: Class
subclass of: nutrition intervention
IAO_0000115: Abstinence from all or some kinds of food or drink, particularly for religious observance, medical nutrition therapy, or prior to a medical procedure.
date: 2019-01-19T21:01:21Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C63663
has exact synonym: NPO
has exact synonym: fasting
has exact synonym: nil per os
has exact synonym: therapeutic fasting
has narrow synonym: intermittant fasting

Axiom
annotated source: fasting intervention
annotated property: IAO_0000115
annotated target: Abstinence from all or some kinds of food or drink, particularly for religious observance, medical nutrition therapy, or prior to a medical procedure.
has db xref: https://orcid.org/0000-0002-7463-6306
has db xref: PMID:16630428
has db xref: PMID:27499591

Axiom
annotated source: fasting intervention
annotated property: hasExactSynonym
annotated target: NPO
has synonym type: OMO_0003000

obsolete food consumption avoidance
type: Class
IAO_0100001: nutrition intake avoidance
deprecated: true

obsolete meat consumption avoidance
type: Class
IAO_0100001: MAXO_0010052
deprecated: true

obsolete nut consumption avoidance
type: Class
IAO_0100001: MAXO_0010053
deprecated: true

obsolete seafood consumption avoidance
type: Class
IAO_0100001: MAXO_0010055
deprecated: true

obsolete mussel consumption avoidance
type: Class
IAO_0100001: MAXO_0010056
deprecated: true

obsolete iron supplementation avoidance
type: Class
IAO_0100001: MAXO_0010100
deprecated: true

obsolete saffron consumption avoidance
type: Class
IAO_0100001: MAXO_0010054
deprecated: true

nutritional supplementation
type: Class
subclass of: dietary intervention
IAO_0000115: The addition of one or more elements and/or chemical compounds that are either absent or deficient in an individual's daily diet.
date: 2019-01-19T21:07:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15425

Axiom
annotated source: nutritional supplementation
annotated property: IAO_0000115
annotated target: The addition of one or more elements and/or chemical compounds that are either absent or deficient in an individual's daily diet.
has db xref: NCIT:C15425

multivitamin supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: FOODON_03315171
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: FOODON_03315171
IAO_0000115: Addition of multivitamin preparation to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-01-19T09:00:01Z
has db xref: NCIT:C1654
has exact synonym: dietary supplementation of multivitamin preparation
has exact synonym: multivitamin preparation supplemental intake
has exact synonym: supplementation of multivitamin preparation
has exact synonym: supplementation with multivitamin
comment: A dietary supplement containing all or most of the vitamins that may not be readily available in the diet. Vitamins may be classified according to their solubility either in lipids (vitamins A, D, E, K, F) or in water (vitamins C, B-complex). Present in minute amounts in various foods, vitamins are essential to maintaining normal metabolism and biochemical functions.

Axiom
annotated source: multivitamin supplementation
annotated property: comment
annotated target: A dietary supplement containing all or most of the vitamins that may not be readily available in the diet. Vitamins may be classified according to their solubility either in lipids (vitamins A, D, E, K, F) or in water (vitamins C, B-complex). Present in minute amounts in various foods, vitamins are essential to maintaining normal metabolism and biochemical functions.
has db xref: NCIT:C1654

iron supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_18248
subclass of: micronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_18248
IAO_0000115: Addition of iron atom to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-01-30T09:00:01Z
has exact synonym: dietary supplementation of iron atom
has exact synonym: iron atom supplemental intake
has exact synonym: oral iron supplementation
has exact synonym: supplementation of iron atom
has narrow synonym: iron replacement therapy
comment: Oral iron supplementation is an effective and well‐studied option to replenish iron stores.

Axiom
annotated source: iron supplementation
annotated property: comment
annotated target: Oral iron supplementation is an effective and well‐studied option to replenish iron stores.
has db xref: PMID:28328083

vitamin C supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176783
subclass of: water-soluble supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176783
IAO_0000115: Addition of vitamin C to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of vitamin C
has exact synonym: supplementation of vitamin C
has exact synonym: vitamin C supplemental intake

vitamin D supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27300
subclass of: fat-soluble vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27300
IAO_0000115: Addition of vitamin D to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-01-19T09:00:01Z
has exact synonym: dietary supplementation of vitamin D
has exact synonym: supplementation of vitamin D
has exact synonym: vitamin D supplemental intake

obsolete amino acid supplementation
type: Class
IAO_0100001: MAXO_0010020
deprecated: true

food antioxidant supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_77962
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_77962
IAO_0000115: Addition of food antioxidant to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-01-19T21:12:19Z
has db xref: NCIT:C67025
has exact synonym: antioxidant therapy
has exact synonym: dietary supplementation of food antioxidant
has exact synonym: food antioxidant supplemental intake
has exact synonym: supplementation of food antioxidant
comment: Treatment with antioxidants in order to protect cells against damage caused by oxygen-free radicals.

Axiom
annotated source: food antioxidant supplementation
annotated property: comment
annotated target: Treatment with antioxidants in order to protect cells against damage caused by oxygen-free radicals.
has db xref: NCIT:C67025

gavage nutrition intake
type: Class
subclass of: enteral nutrition intake
IAO_0000115: Administration of nutritional support by means of a tube passed into the stomach.
date: 2019-01-19T21:13:59Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C73430
has exact synonym: gastrogavage nutrition intake

Axiom
annotated source: gavage nutrition intake
annotated property: IAO_0000115
annotated target: Administration of nutritional support by means of a tube passed into the stomach.
has db xref: NCIT:C73430

total parenteral nutrition intake
type: Class
subclass of: parenteral nutrition intake
IAO_0000115: Total parenteral nutrition formulated for intravenous administration in patients who cannot eat or cannot get enough nutrients from the foods they eat. It is a liquid mixture of proteins, carbohydrates, fats, vitamins, minerals and other nutrients.
date: 2019-01-19T21:16:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C29484
has exact synonym: TNA intake
has exact synonym: TPN intake
has exact synonym: total nutrient admixture intake
has narrow synonym: hyperalimentation

Axiom
annotated source: total parenteral nutrition intake
annotated property: IAO_0000115
annotated target: Total parenteral nutrition formulated for intravenous administration in patients who cannot eat or cannot get enough nutrients from the foods they eat. It is a liquid mixture of proteins, carbohydrates, fats, vitamins, minerals and other nutrients.
has db xref: NCIT:C29484

Axiom
annotated source: total parenteral nutrition intake
annotated property: hasExactSynonym
annotated target: TPN intake
has synonym type: OMO_0003000

memory intervention
type: Class
subclass of: cognitive and behavioral intervention
IAO_0000115: Any action taken for the purpose of improving or maintaining an individual's memory.
date: 2019-01-19T21:26:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116526
has exact synonym: working memory interventions
has narrow synonym: memory aids

smoking prevention
type: Class
subclass of: behavioral preventative care
IAO_0000115: A behavioral modification or implementation of a behavior designed to prevent smoking.
date: 2019-01-19T21:33:17Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16114
has exact synonym: prevent smoking

Axiom
annotated source: smoking prevention
annotated property: IAO_0000115
annotated target: A behavioral modification or implementation of a behavior designed to prevent smoking.
has db xref: https://orcid.org/0000-0002-7463-6306

contraceptive pregnancy prevention
type: Class
subclass of: preventative therapy
subclass of: obstetrics and gynecology procedure
IAO_0000115: The prevention of conception or impregnation by the use of devices or drugs or surgery.
date: 2019-01-19T21:34:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C37932
has exact synonym: birth control
has exact synonym: conception prevention
has exact synonym: contraceptive management
has exact synonym: pregnancy prevention

Axiom
annotated source: contraceptive pregnancy prevention
annotated property: IAO_0000115
annotated target: The prevention of conception or impregnation by the use of devices or drugs or surgery.
has db xref: NCIT:C37932

Axiom
annotated source: contraceptive pregnancy prevention
annotated property: hasExactSynonym
annotated target: birth control
has db xref: NCIT:C37932

preventative immunization
type: Class
subclass of: preventative therapy
IAO_0000115: Immunization is the process whereby a person is made immune or resistant to an infectious disease, typically by the administration of a vaccine.
date: 2019-01-19T21:36:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15258
has db xref: OBI:1110094
has exact synonym: immunization
has exact synonym: preventive immunization

Axiom
annotated source: preventative immunization
annotated property: IAO_0000115
annotated target: Immunization is the process whereby a person is made immune or resistant to an infectious disease, typically by the administration of a vaccine.
has db xref: WHO

Axiom
annotated source: preventative immunization
annotated property: hasExactSynonym
annotated target: immunization
has db xref: NCIT:C15258
has db xref: OBI:1110094

active immunization
type: Class
subclass of: preventative immunization
IAO_0000115: Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long lasting—even lifelong.
date: 2019-01-20T00:31:42Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: IDO:0000498
has db xref: NCIT:C15416
has db xref: VO:0000491

Axiom
annotated source: active immunization
annotated property: IAO_0000115
annotated target: Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long lasting—even lifelong.
has db xref: PMID:18045976

passive immunization
type: Class
subclass of: preventative immunization
IAO_0000115: Passive immunity refers to the process of providing IgG antibodies to protect against infection; it gives immediate, but short-lived protection.
date: 2019-01-20T00:31:52Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15259
has db xref: OBI:0001174
has db xref: VO:0000492

Axiom
annotated source: passive immunization
annotated property: IAO_0000115
annotated target: Passive immunity refers to the process of providing IgG antibodies to protect against infection; it gives immediate, but short-lived protection.
has db xref: PMID:18045976

disease exposure immunization
type: Class
subclass of: active immunization
IAO_0000115: The intentional exposure to a disease in order to achieve immunization.
date: 2019-01-20T00:36:49Z
creator: http://orcid.org/0000-0001-7941-2961

disease screening
type: Class
subclass of: diagnostic procedure
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence of disease, usually in asymptomatic individuals.
date: 2019-01-20T00:39:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15419

Axiom
annotated source: disease screening
annotated property: IAO_0000115
annotated target: The use of any device, marker, or other means for the purpose of detecting the presence of disease, usually in asymptomatic individuals.
has db xref: NCIT:C15419

audiometric testing
type: Class
subclass of: hearing examination
IAO_0000115: Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss.
date: 2019-01-20T00:42:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38036
has exact synonym: audiometry test
has exact synonym: hearing exam procedure
has exact synonym: hearing testing procedure
comment: audiometry exam

Axiom
annotated source: audiometric testing
annotated property: IAO_0000115
annotated target: Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss.
has db xref: NCIT:C38036

cancer screening
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0002664
subclass of: disease screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0002664
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Neoplasm, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
date: 2019-01-20T00:45:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15406
has exact synonym: Neoplasm screening

genetic testing
type: Class
subclass of: clinical laboratory procedure
subclass of: disease screening
IAO_0000115: The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder.
date: 2019-01-20T00:46:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15709
has exact synonym: genetic analysis

Axiom
annotated source: genetic testing
annotated property: IAO_0000115
annotated target: The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder.
has db xref: NCIT:C15709

obsolete prenatal screening
type: Class
IAO_0100001: prenatal examination
deprecated: true

obsolete biopsy procedure
type: Class
IAO_0100001: OBI_0002650
deprecated: true

endoscopic procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: A diagnostic or therapeutic procedure in which an endoscope is inserted in a tubular organ to examine the structural architecture and/or remove abnormal tissues.
date: 2019-01-20T01:01:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16546
has exact synonym: endoscopic exam
has exact synonym: endoscopy

Axiom
annotated source: endoscopic procedure
annotated property: IAO_0000115
annotated target: A diagnostic or therapeutic procedure in which an endoscope is inserted in a tubular organ to examine the structural architecture and/or remove abnormal tissues.
has db xref: NCIT:C16546

Axiom
annotated source: endoscopic procedure
annotated property: hasExactSynonym
annotated target: endoscopy
has db xref: NCIT:C16546

endoscopy by site
type: Class
equivalent class: Class
  intersection of: endoscopic procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: endoscopic procedure
subclass of: clinical imaging procedure by system
IAO_0000115: A diagnostic or therapeutic procedure in which an endoscope is inserted in a tubular portion of a specific body part or body location.
date: 2019-01-20T01:03:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: endoscopy by body location
has exact synonym: location specific endoscopy

specific technique endoscopy
type: Class
subclass of: endoscopic procedure
IAO_0000115: A diagnostic or therapeutic procedure in which an endoscope is inserted in a tubular organ using a specific endoscopic technique.
date: 2019-01-20T01:03:28Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: endoscopy by type
has exact synonym: specific type endoscopy

balloon-guided endoscopic procedure
type: Class
subclass of: specific technique endoscopy
IAO_0000115: An endoscopic technique that allows deep intubation of the small intestine while using a standard endoscope. An inflatable balloon attached to the endoscope's tip acts as a stabilizer and a second balloon that is advanced ahead of the endoscope acts as a pulling device.
date: 2019-01-20T18:48:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64865
has exact synonym: balloon-guided endoscopy

Axiom
annotated source: balloon-guided endoscopic procedure
annotated property: IAO_0000115
annotated target: An endoscopic technique that allows deep intubation of the small intestine while using a standard endoscope. An inflatable balloon attached to the endoscope's tip acts as a stabilizer and a second balloon that is advanced ahead of the endoscope acts as a pulling device.
has db xref: NCIT:C64865

chromoendoscopy
type: Class
subclass of: specific technique endoscopy
IAO_0000115: Endoscopy that employs the use of tissue stains to increase tissue contrast, and enhance the ability to identify various tissue dysplasia and other abnormalities.
date: 2019-01-20T18:51:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116476

Axiom
annotated source: chromoendoscopy
annotated property: IAO_0000115
annotated target: Endoscopy that employs the use of tissue stains to increase tissue contrast, and enhance the ability to identify various tissue dysplasia and other abnormalities.
has db xref: NCIT:C116476

high-resolution microendoscopy
type: Class
subclass of: specific technique endoscopy
IAO_0000115: A low-cost, high-resolution imaging tool consisting of a 1-mm diameter fiber-optic bundle that produces subcellular imaging at 1,000x magnification and 4 micrometer resolution, allowing for minimally invasive bioimaging.
date: 2019-01-20T19:03:17Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116480
has exact synonym: HRME

Axiom
annotated source: high-resolution microendoscopy
annotated property: IAO_0000115
annotated target: A low-cost, high-resolution imaging tool consisting of a 1-mm diameter fiber-optic bundle that produces subcellular imaging at 1,000x magnification and 4 micrometer resolution, allowing for minimally invasive bioimaging.
has db xref: NCIT:C116480

Axiom
annotated source: high-resolution microendoscopy
annotated property: hasExactSynonym
annotated target: HRME
has synonym type: OMO_0003000

positron emission tomography procedure
type: Class
subclass of: nuclear medicine imaging procedure
IAO_0000115: A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.
has db xref: NCIT:C17007
has exact synonym: PET scan

Axiom
annotated source: positron emission tomography procedure
annotated property: IAO_0000115
annotated target: A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.
has db xref: NCIT:C17007

Axiom
annotated source: positron emission tomography procedure
annotated property: hasExactSynonym
annotated target: PET scan
has db xref: NCIT:C17007
has synonym type: OMO_0003000

contrast-enhanced ultrasound procedure
type: Class
subclass of: ultrasonography procedure
IAO_0000115: Ultrasound imaging following the administration of a microbubble contrast agent.
date: 2019-01-21T20:17:52Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C148281
has exact synonym: CEUS

Axiom
annotated source: contrast-enhanced ultrasound procedure
annotated property: IAO_0000115
annotated target: Ultrasound imaging following the administration of a microbubble contrast agent.
has db xref: NCIT:C148281

Axiom
annotated source: contrast-enhanced ultrasound procedure
annotated property: hasExactSynonym
annotated target: CEUS
has synonym type: OMO_0003000

autopsy procedure
type: Class
subclass of: surgical procedure
IAO_0000115: A postmortem examination of the body that includes an examination of the internal organs and structures after dissection to determine the cause of death and the nature of pathological changes.
date: 2019-01-21T20:33:46Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C25153
has exact synonym: autopsy

Axiom
annotated source: autopsy procedure
annotated property: IAO_0000115
annotated target: A postmortem examination of the body that includes an examination of the internal organs and structures after dissection to determine the cause of death and the nature of pathological changes.
has db xref: NCIT:C25153

clinical cytological testing
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: A procedure to examine and define cellular anatomy or function. The test results are often used by a clinician to diagnose disease or disordered function.
date: 2019-01-21T20:36:01Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49132
has exact synonym: clinical cytological procedure
has narrow synonym: diagnostic cytological procedure

pap smear examination
type: Class
subclass of: cancer screening
subclass of: clinical cytological testing
subclass of: obstetrics and gynecology procedure
IAO_0000115: A biospecimen collection and staining procedure in which secretions and superficial cells of the cervix are collected and stained with the Papanicolaou stain followed by microscopic examination to identify the presence of abnormal cells.
date: 2019-01-21T20:38:23Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Papanicolaou smear procedure
has exact synonym: cervical smear procedure
has exact synonym: pap testing
has related synonym: cervical cancer screening

Axiom
annotated source: pap smear examination
annotated property: IAO_0000115
annotated target: A biospecimen collection and staining procedure in which secretions and superficial cells of the cervix are collected and stained with the Papanicolaou stain followed by microscopic examination to identify the presence of abnormal cells.
has db xref: NCIT:C17348

Axiom
annotated source: pap smear examination
annotated property: hasExactSynonym
annotated target: Papanicolaou smear procedure
has db xref: NCIT:C17348

Axiom
annotated source: pap smear examination
annotated property: hasExactSynonym
annotated target: cervical smear procedure
has db xref: NCIT:C17348

Axiom
annotated source: pap smear examination
annotated property: hasExactSynonym
annotated target: pap testing
has db xref: NCIT:C17348

sputum cytology examination
type: Class
subclass of: clinical cytological testing
IAO_0000115: A diagnostic technique for lung cancer detection. Looks for abnormal cell cytology in sputum.
date: 2019-01-21T20:45:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16192
has exact synonym: sputum cytology testing
has exact synonym: sputum smear examination
has exact synonym: sputum smear testing

Axiom
annotated source: sputum cytology examination
annotated property: IAO_0000115
annotated target: A diagnostic technique for lung cancer detection. Looks for abnormal cell cytology in sputum.
has db xref: NCIT:C16192

urine cytology examination
type: Class
subclass of: clinical cytological testing
IAO_0000115: Examination of the cells in urine.
date: 2019-01-21T20:47:27Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: urine cytology testing

Axiom
annotated source: urine cytology examination
annotated property: IAO_0000115
annotated target: Examination of the cells in urine.
has db xref: NCIT:C94473

histological examination
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: Technique or procedure used for the study of the microanatomy of tissues and their cellular structure; usually involves microscopic examination of tissue slices.
date: 2019-01-21T21:04:01Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16680
has exact synonym: histological procedure
has exact synonym: histological testing

Axiom
annotated source: histological examination
annotated property: IAO_0000115
annotated target: Technique or procedure used for the study of the microanatomy of tissues and their cellular structure; usually involves microscopic examination of tissue slices.
has db xref: NCIT:C16680

obsolete clinical pathology procedure
type: Class
deprecated: true

clinical cell count
type: Class
subclass of: cell measurement
IAO_0000115: A procedure to determine the number of cells in a clinical sample.
date: 2019-01-21T21:16:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C48938
has exact synonym: cell count
has narrow synonym: clinical pathology cell count

Axiom
annotated source: clinical cell count
annotated property: IAO_0000115
annotated target: A procedure to determine the number of cells in a clinical sample.
has db xref: NCIT:C48938

hematology testing
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: A procedure to measure hematopoietic components and investigate hematologic disorders in a blood sample.
date: 2019-01-21T21:22:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49286
has exact synonym: blood testing
has exact synonym: hematology procedure

oxygen capacity assessment
type: Class
subclass of: hematology testing
IAO_0000115: The determination of the maximum amount of oxygen that can be combined chemically with hemoglobin in a volume of blood.
date: 2019-01-21T21:29:03Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C96614
has exact synonym: OXYCAP testing
has exact synonym: oxygen capacity measurement
has exact synonym: oxygen capacity testing

Axiom
annotated source: oxygen capacity assessment
annotated property: IAO_0000115
annotated target: The determination of the maximum amount of oxygen that can be combined chemically with hemoglobin in a volume of blood.
has db xref: NCIT:C96614

Axiom
annotated source: oxygen capacity assessment
annotated property: hasExactSynonym
annotated target: OXYCAP testing
has synonym type: OMO_0003000

hematocrit assessment
type: Class
subclass of: hematology testing
IAO_0000115: A measure of the volume of red blood cells expressed as a percentage of the total blood volume. Normal in males is 43-49%, in females 37-43%.
date: 2019-01-21T21:32:32Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64796
has exact synonym: EVF testing
has exact synonym: HCT
has exact synonym: PCV measurement
has exact synonym: erythrocyte volume fraction testing
has exact synonym: hematocrit measurement
has exact synonym: hematocrit testing
has exact synonym: packed cell volume measurement

Axiom
annotated source: hematocrit assessment
annotated property: IAO_0000115
annotated target: A measure of the volume of red blood cells expressed as a percentage of the total blood volume. Normal in males is 43-49%, in females 37-43%.
has db xref: NCIT:C64796

Axiom
annotated source: hematocrit assessment
annotated property: hasExactSynonym
annotated target: EVF testing
has synonym type: OMO_0003000

Axiom
annotated source: hematocrit assessment
annotated property: hasExactSynonym
annotated target: HCT
has synonym type: OMO_0003000

Axiom
annotated source: hematocrit assessment
annotated property: hasExactSynonym
annotated target: PCV measurement
has synonym type: OMO_0003000

Axiom
annotated source: hematocrit assessment
annotated property: hasExactSynonym
annotated target: packed cell volume measurement
has db xref: NCIT:C64796

therapeutic avoidance intervention
type: Class
subclass of: therapeutic procedure
IAO_0000115: A medical recommendation to avoid a particular therapy, intervention, medication, or procedure.
date: 2019-01-07T19:23:10Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: avoid procedure
has exact synonym: avoid therapy
has narrow synonym: avoid activity
has narrow synonym: avoid drug
has narrow synonym: avoid medication

Axiom
annotated source: therapeutic avoidance intervention
annotated property: IAO_0000115
annotated target: A medical recommendation to avoid a particular therapy, intervention, medication, or procedure.
has db xref: https://orcid.org/0000-0001-7941-2961

augmentation therapy
type: Class
subclass of: biologic therapy
IAO_0000115: Administration of intravenous infusions of alpha-1 proteinase inhibitor at regular schedules is a specific therapy for individuals with alpha-1 antitrypsin deficiency (AATD) with pulmonary involvement.
date: 2019-01-22T17:27:25Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: augmentation therapy
annotated property: IAO_0000115
annotated target: Administration of intravenous infusions of alpha-1 proteinase inhibitor at regular schedules is a specific therapy for individuals with alpha-1 antitrypsin deficiency (AATD) with pulmonary involvement.
has db xref: PMID:28752465

obsolete antispastic agents
type: Class
IAO_0100001: antispasticity agent therapy
deprecated: true

antiparkinson agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48407
subclass of: antidyskinesia agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48407
IAO_0000115: Treatment with a drug used in the treatment of Parkinson's disease.
date: 2019-01-22T17:52:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48407
has db xref: NCIT:C38149
has exact synonym: anti-Parkinson agent therapy
has exact synonym: antiparkinson agent treatment
has exact synonym: antiparkinson drug treatment
has exact synonym: antiparkinsonian agent therapy
has exact synonym: antiparkisonian agent treatment
has exact synonym: antiparkisonian drug treatment
has exact synonym: treatment with anti-Parkinson drug
has exact synonym: treatment with antiparkinson drug

antiparasititic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35442
subclass of: anti-infective agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35442
IAO_0000115: Use of a substance used to treat or prevent parasitic infections.
date: 2019-01-22T17:53:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35442
has db xref: NCIT:C276
has exact synonym: antiparasitic drug therapy
has exact synonym: antiparasitics therapy
has exact synonym: antiparisitics drug treatment
has exact synonym: treatment with anti-parasitic agent
has exact synonym: treatment with anti-parasitic medication
has exact synonym: treatment with antiparasitic agent
has exact synonym: treatment with antiparasitic drug
has exact synonym: treatment with antiparasitic medication

analgesic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35480
subclass of: pharmacotherapy
subclass of: pain management
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35480
IAO_0000115: A therapy capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
date: 2019-01-22T17:53:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35480
has db xref: NCIT:C241
has exact synonym: Analgesics therapy
has exact synonym: analgesic drug therapy
has exact synonym: analgesic medication therapy
has exact synonym: analgesic pharmacotherapeutic agent therapy
has exact synonym: treatment with analgesic

antidepressant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35469
subclass of: psychotropic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35469
IAO_0000115: Treatment with a mood-stimulating drug used primarily in the treatment of affective disorders and related conditions.
date: 2019-01-22T17:53:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35469
has exact synonym: antidepressant drug therapy
has exact synonym: antidepressants treatment
has exact synonym: thymoanaleptics treatment
has exact synonym: thymoleptic agent therapy
has exact synonym: thymoleptic drug treatment therapy
has exact synonym: thymoleptics drug therapy
has exact synonym: treatment with antidepressant

receptor antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48706
subclass of: molecular pathway modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48706
IAO_0000115: Use of a substance that attaches to and blocks cell receptors.
date: 2019-01-22T17:54:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48706
has db xref: NCIT:C69308
has exact synonym: treatment with antagonist

adrenal-modifying, hormonal agent therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Use of any agent that can alter adrenal gland functions.
date: 2019-01-22T17:54:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with adrenal modifier
has exact synonym: treatment with adrenal modifying agent
has exact synonym: treatment with adrenal modifying drug
has exact synonym: treatment with adrenal modifying medication
comment: adrenal hormone modifying therapy

anxiolytic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35474
subclass of: mood and behavior-altering agent therapy
subclass of: psychotropic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35474
IAO_0000115: Treatment with a drug that alleviates anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting the clarity of consciousness or neurologic conditions.
date: 2019-01-22T17:54:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35474
has exact synonym: anti-anxiety agent therapy
has exact synonym: anti-anxiety drug treatment
has exact synonym: anxiolytic agent drug treatment
has exact synonym: minor tranquiliser therapy
has exact synonym: minor tranquilizer treatment
has exact synonym: minor tranquilizing agent treatment
has exact synonym: minor tranquilizing drug therapy
has exact synonym: treatment with anxiolytic
has exact synonym: treatment with anxiolytic drug

uricosuric agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35841
subclass of: antirheumatic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35841
IAO_0000115: Pharmaceutical Anti-gout Preparations such as colchicine, allopurinol, probenecid, and sulfinpyrazone contain natural or synthetic agents against gout, a condition characterized by increased uric acid accumulation. Anti-gout agents may reduce inflammation, stimulate elimination of uric acid, or increase production of uric acid. (NCI04)
date: 2019-01-22T17:55:18Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35841
has db xref: CHEBI:35845
has db xref: NCIT:C29733
has exact synonym: anti-gout agent therapy
has exact synonym: anti-gout combination medicine therapy
has exact synonym: anti-gout drug therapy
has exact synonym: anti-gout preparation therapy
has exact synonym: antigout agent therapy
has exact synonym: antigout combination medicine therapy
has exact synonym: antigout drug therapy
has exact synonym: antigout medication therapy
has exact synonym: antigout preparation therapy
has exact synonym: antigout therapy
has exact synonym: gout suppressant agent treatment
has exact synonym: treatment with anti-gout drug
has exact synonym: treatment with anti-gout medication
has exact synonym: treatment with antigout agent
has exact synonym: treatment with antigout drug
has exact synonym: treatment with antigout medication
has exact synonym: treatment with gout suppressant agent
has exact synonym: treatment with gout suppressant drug
has exact synonym: treatment with gout suppressant medication
has exact synonym: treatment with uricosuric drug

Axiom
annotated source: uricosuric agent therapy
annotated property: IAO_0000115
annotated target: Pharmaceutical Anti-gout Preparations such as colchicine, allopurinol, probenecid, and sulfinpyrazone contain natural or synthetic agents against gout, a condition characterized by increased uric acid accumulation. Anti-gout agents may reduce inflammation, stimulate elimination of uric acid, or increase production of uric acid. (NCI04)
has db xref: NCIT:C29733

diuretic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35498
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35498
IAO_0000115: Therapy using an agent that promotes the excretion of urine through its effects on kidney function
date: 2019-01-22T17:55:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35498
has db xref: NCIT:C448
has exact synonym: diuretic agent drug treatment therapy
has exact synonym: diuretic drug therapy
has exact synonym: treatment with diuretic
has exact synonym: treatment with diuretic agent
has exact synonym: treatment with diuretic drug
has exact synonym: treatment with diuretic medication

antipsychotic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35476
subclass of: mood and behavior-altering agent therapy
subclass of: psychotropic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35476
IAO_0000115: Treatment with an agent that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
date: 2019-01-22T17:57:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35476
has exact synonym: antipsychotic drug treatment
has exact synonym: antipsychotic therapy
has exact synonym: major tranquilizer drug treatment
has exact synonym: neuroleptic agent treatment
has exact synonym: neuroleptic therapies
has exact synonym: treatment with antipsychotic agent
has exact synonym: treatment with antipsychotic drug
has exact synonym: treatment with antipsychotic medication

anticonvulsant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35623
subclass of: central nervous system agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35623
IAO_0000115: Treatment with a drug used to prevent seizures or reduce their severity.
date: 2019-01-22T17:57:37Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35623
has db xref: NCIT:C264
has exact synonym: anti-convulsant therapy
has exact synonym: anti-convulsive agent therapy
has exact synonym: anticonvulsant drug therapy
has exact synonym: anticonvulsive agent therapy
has exact synonym: antiepileptic therapy
has exact synonym: treatment with anticonvulsant
has exact synonym: treatment with anticonvulsant medication

antiviral agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_36044
subclass of: antimicrobial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_36044
IAO_0000115: Treatment with a substance used in the prophylaxis or therapy of virus diseases.
date: 2019-01-22T17:57:52Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:36044
has exact synonym: anti-viral drug therapy
has exact synonym: anti-virus drug treatment
has exact synonym: treatment with an anti-virus agent
has exact synonym: treatment with an anti-virus drug
has exact synonym: treatment with an anti-virus medication
has exact synonym: treatment with an antiviral agent
has exact synonym: treatment with an antiviral drug
has exact synonym: treatment with an antiviral medication
has exact synonym: treatment with antiviral drug

anti-inflammatory agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35472
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35472
IAO_0000115: Use of a compound that has anti-inflammatory effects.
date: 2019-01-22T17:58:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:67079
has exact synonym: anti-inflammatory agent treatment therapy
has exact synonym: anti-inflammatory medication therapy
has exact synonym: antiinflammatory agent therapy
has exact synonym: antiinflammatory drug therapy
has exact synonym: treatment with anti-inflammatory drug

anesthetic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38867
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38867
IAO_0000115: A therapy utilizing a substance which produces loss of feeling or sensation.
date: 2019-01-22T17:59:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38867
has db xref: NCIT:C245
has exact synonym: anaesthesia therapy
has exact synonym: anaesthetic medication therapy
has exact synonym: anesthesia therapy
has exact synonym: anesthetic drug therapy
has exact synonym: anesthetic medication therapy
has exact synonym: treatment with anaesthetic

antidementia agent therapy
type: Class
subclass of: central nervous system agent therapy
IAO_0000115: Treatment with medications to improve cognition and function for patients with dementia.
date: 2019-01-22T18:00:43Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: antidementia drug therapy
has exact synonym: antidementia medication treatment

Axiom
annotated source: antidementia agent therapy
annotated property: IAO_0000115
annotated target: Treatment with medications to improve cognition and function for patients with dementia.
has db xref: PMID:31517030

therapeutic antidotes, deterrents, and toxicologic agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: A grouping of agents that are used as antidotes, deterrents, or to counteract the effects of a toxic agents on the body.
date: 2019-01-22T18:01:36Z
creator: http://orcid.org/0000-0001-7941-2961
has related synonym: antidote therapy
has related synonym: rescue therapy

antiemetic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50919
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50919
IAO_0000115: Treatment with a drug used to prevent nausea or vomiting.
date: 2019-01-22T18:01:53Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50919
has db xref: NCIT:C267
has exact synonym: anti-emetic agent therapy
has exact synonym: anti-emetic drug therapy
has exact synonym: anti-emetics therapy
has exact synonym: antiemetic drug therapy
has exact synonym: antiemetics medication treatment
has exact synonym: medication for nausea treatment
has exact synonym: medication for treatment of nausea
has exact synonym: treatment with antiemetic

anti-fungal agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_86327
subclass of: anti-infective agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_86327
IAO_0000115: Use of a drug to prevent or treat fungal infections in humans or animals.
date: 2019-01-22T18:02:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:86327
has exact synonym: anti-fungal drug therapy
has exact synonym: anti-fungal medication therapy
has exact synonym: antifungal treatment
has exact synonym: antifungals therapy
has exact synonym: treatment with an anti-fungal drug
has exact synonym: treatment with an anti-fungal medication
has exact synonym: treatment with an antifungal drug
has exact synonym: treatment with an antifungal medication
has exact synonym: treatment with an antifungal therapy
has exact synonym: treatment with antifungal drug
has narrow synonym: pharmaceutical fungicide therapy

blood glucose regulator therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Any drug that works to lower abnormally high glucose (sugar) levels in the blood, which are characteristic of the endocrine system disorder known as diabetes mellitus.
date: 2019-01-22T18:11:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: blood glucose regulator drug treatment
has related synonym: Treatment with an agent that regulates blood glucose levels.

hematologic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50248
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50248
IAO_0000115: Use of a drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
date: 2019-01-22T18:11:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: DBCAT000008
has db xref: CHEBI:50248
has exact synonym: blood modifier treatment therapy
has exact synonym: blood modifying agent treatment
has exact synonym: hematologic agent treatment therapy
has exact synonym: treatment with hematologic agent
has exact synonym: treatment with hematologic drug
has exact synonym: treatment with hematologic medication

coagulant agent therapy
type: Class
subclass of: hematologic agent therapy
IAO_0000115: Treatment with a drug that promotes coagulation.
date: 2019-01-22T18:11:58Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: coagulant treatment therapy
has exact synonym: coagulation factor replacement therapy
has exact synonym: promotion of coagulation
has exact synonym: treatment with coagulant

anticoagulant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50249
subclass of: hematologic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50249
IAO_0000115: Use of an agent that prevents blood clotting.
date: 2019-01-22T18:12:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50249
has exact synonym: anticoagulant agent treatment
has exact synonym: anticoagulant drug treatment
has exact synonym: treatment with anticoagulant

blood formation agent therapy
type: Class
subclass of: hematologic agent therapy
IAO_0000115: Treatment with an agent that stimulates formation of blood cells.
date: 2019-01-22T18:12:20Z
creator: http://orcid.org/0000-0001-7941-2961

platelet aggregation inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50427
subclass of: hematologic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50427
IAO_0000115: Use of a drug which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
date: 2019-01-22T18:12:39Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50427
has exact synonym: platelet aggregation inhibitor agent treatment
has exact synonym: treatment with platelet aggregation antagonist
has exact synonym: treatment with platelet aggregation blocker
has exact synonym: treatment with platelet aggregation inhibitor

cardiovascular agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35554
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35554
IAO_0000115: Use of a drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
date: 2019-01-22T18:13:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35554
has db xref: NCIT:C78274
has exact synonym: agent affecting cardiovascular system therapy
has exact synonym: cardiovascular agent drug treatment
has exact synonym: cardiovascular drug treatment therapy
has exact synonym: cardiovascular system agent therapy
has exact synonym: cardiovascular system drug therapy
has exact synonym: treatment with cardiovascular agent
has exact synonym: treatment with cardiovascular drug
has exact synonym: treatment with cardiovascular medication
has exact synonym: treatment with cardiovascular therapy
has narrow synonym: treatment with heart agent
has narrow synonym: treatment with heart drug
has narrow synonym: treatment with heart medication

alpha adrenergic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48539
subclass of: adrenergic drug therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48539
IAO_0000115: Treatment with a drug that acts on an alpha-adrenergic receptor.
date: 2019-01-22T18:14:42Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48539
has exact synonym: a-adrenergic agent therapy
has exact synonym: a-adrenergic drug therapy
has exact synonym: a-adrenergic receptor agent therapy
has exact synonym: a-adrenergic receptor drug therapy
has exact synonym: alpha adrenergic drug therapy
has exact synonym: alpha adrenergic receptor agent therapy
has exact synonym: alpha adrenergic receptor drug treatment
has exact synonym: alpha adrenergics drug therapy
has exact synonym: alpha-adrenergic agent treatment
has exact synonym: alpha-adrenergic drug treatment therapy
has exact synonym: alpha-adrenergic modifier therapy
has exact synonym: alpha-adrenergic modifying agent therapy
has exact synonym: alpha-adrenergic receptor agent therapy
has exact synonym: alpha-adrenergic receptor drug therapy
has exact synonym: alpha-adrenergic receptor drug treatment
has exact synonym: treatment with alpha adrenergic agent
has exact synonym: treatment with alpha adrenergic drug
has exact synonym: treatment with alpha adrenergic medication
has exact synonym: treatment with alpha-adrenergic agent
has exact synonym: treatment with alpha-adrenergic drug
has exact synonym: treatment with alpha-adrenergic medication
has exact synonym: treatment with alpha-adrenergic receptor agent
has exact synonym: treatment with alpha-adrenergic receptor drug
has exact synonym: treatment with alpha-adrenergic receptor medication

alpha adrenergic agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35569
subclass of: alpha adrenergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35569
IAO_0000115: Treatment with an agent that selectively binds to and activates alpha-adrenergic receptors.
date: 2019-01-22T18:15:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48539
has exact synonym: a-adrenergic agonist drug treatment
has exact synonym: a-adrenergic agonist therapy
has exact synonym: a-adrenergic receptor agonist therapy
has exact synonym: alpha adrenergic agonist agent drug treatment
has exact synonym: alpha adrenergic agonist drug therapy
has exact synonym: alpha adrenergic agonist treatment
has exact synonym: alpha adrenergic receptor agonist therapy
has exact synonym: alpha adrentergic receptor agonist agent therapy
has exact synonym: alpha-adrenergic receptor agonist drug therapy
has exact synonym: alpha-adrenergic receptor agonist treatment
has exact synonym: alpha-adrenoceptor agonist agent therapy
has exact synonym: alpha-adrenoceptor agonist drug therapy
has exact synonym: alpha-adrenoceptor agonist therapy
has exact synonym: treatment with alpha-adrenergic agonist

alpha adrenergic antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37890
subclass of: alpha adrenergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_37890
IAO_0000115: Treatment with an agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists.
date: 2019-01-22T18:15:59Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:37890
has exact synonym: a-adrenergic antagonist agent therapy
has exact synonym: a-adrenergic antagonist therapy
has exact synonym: a-adrenergic receptor antagonist drug treatment
has exact synonym: alpha adrenergic antagonist drug therapy
has exact synonym: alpha blocker therapy
has exact synonym: alpha-adrenergic antagonist agent treatment
has exact synonym: alpha-adrenergic antagonist drug therapy
has exact synonym: alpha-adrenergic antagonist drug treatment
has exact synonym: alpha-adrenergic antagonist medication therapy
has exact synonym: alpha-adrenergic blockader therapy
has exact synonym: alpha-adrenergic blocker therapy
has exact synonym: alpha-adrenergic blocking agent therapy
has exact synonym: alpha-adrenergic receptor antagonist agent therapy
has exact synonym: alpha-adrenergic receptor antagonist drug therapy
has exact synonym: alpha-adrenergic receptor blockader therapy
has exact synonym: alpha-adrenergic receptor blocker therapy
has exact synonym: alpha-adrenoceptor antagonist therapy
has exact synonym: treatment with alpha-adrenergic antagonist
has exact synonym: treatment with alpha-adrenergic antagonist drug
has exact synonym: treatment with alpha-adrenergic antagonist medication

antiarrythmic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38070
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38070
IAO_0000115: Treatment with a drug for prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
date: 2019-01-22T18:17:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38070
has db xref: NCIT:C47793
has exact synonym: anti-arrhythmia agent therapy
has exact synonym: anti-arrhythmic agent therapy
has exact synonym: anti-arrhythmic drug treatment therapy
has exact synonym: anti-arrythmic agent therapy
has exact synonym: antiarrhythmic agent therapy
has exact synonym: antiarrhythmic drug therapy
has exact synonym: antiarrhythmic drug treatment
has exact synonym: treatment with anti-arrhythmia agent
has exact synonym: treatment with anti-arrhythmia drug
has exact synonym: treatment with anti-arrhythmia medication
has exact synonym: treatment with anti-arrhythmic agent
has exact synonym: treatment with anti-arrhythmic drug
has exact synonym: treatment with anti-arrhythmic medication
has exact synonym: treatment with anti-arrythmic drug
has exact synonym: treatment with antiarrhythmic agent
has exact synonym: treatment with antiarrhythmic drug
has exact synonym: treatment with antiarrhythmic medication

beta adrenergic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48540
subclass of: adrenergic drug therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48540
IAO_0000115: Treatment with a drug that acts on beta-adrenergic receptors.
date: 2019-01-22T18:17:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48540
has exact synonym: b-adrenergic drug treatment
has exact synonym: beta adrenergic receptor agent treatment
has exact synonym: beta adrenergic receptor drug therapy
has exact synonym: beta-adrenergic agent treatment
has exact synonym: beta-adrenergic drug treatment
has exact synonym: beta-adrenergic modifier therapy
has exact synonym: beta-adrenergic modifying agent therapy
has exact synonym: beta-adrenergic modifying drug treatment
has exact synonym: beta-adrenergics therapy
has exact synonym: treatment with beta-adrenergic agent
has exact synonym: treatment with beta-adrenergic drug
has exact synonym: treatment with beta-adrenergic medication

beta-adrenergic antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35530
subclass of: beta adrenergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35530
IAO_0000115: Treatment with an agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists.
date: 2019-01-22T18:17:55Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35530
has exact synonym: b-adrenergic antagonist therapy
has exact synonym: b-adrenergic receptor antagonist therapy
has exact synonym: beta adrenergic antagonist agent treatment
has exact synonym: beta adrenergic antagonist drug treatment
has exact synonym: beta adrenergic receptor antagonist therapy
has exact synonym: beta-adrenergic antagonist agent treatment
has exact synonym: beta-adrenergic receptor antagonist drug treatment
has exact synonym: beta-adrenergic receptor antagonist therapy
has exact synonym: beta-adrenergic receptor blockader therapy
has exact synonym: beta-adrenoceptor antagonist therapy
has exact synonym: treatment with beta blocker agent
has exact synonym: treatment with beta blocker drug
has exact synonym: treatment with beta blocker medication
has exact synonym: treatment with beta-adrenergic antagonist
has exact synonym: treatment with beta-adrenergic antagonist agent
has exact synonym: treatment with beta-adrenergic antagonist drug
has exact synonym: treatment with beta-adrenergic antagonist medication

obsolete calcium channel blocker agent therapy
type: Class
IAO_0100001: calcium channel blocking agent therapy
deprecated: true

dyslipidemic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35679
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35679
IAO_0000115: Therapy using an agent that reduces plasma lipids, such as cholesterol or low density lipoproteins (LDL), acting systemically or locally (intestines) to decrease fat digestion, absorption, production, and accumulation in the plasma and reducing pathogenic atherosclerosis and thrombosis.
date: 2019-01-22T18:19:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C29703
has exact synonym: anti-lipemic therapy
has exact synonym: anti-lipidemic agent therapy
has exact synonym: antihyperlipemic agent therapy
has exact synonym: antihyperlipidaemic agent therapy
has exact synonym: antihyperlipidemic agent therapy
has exact synonym: antihyperlipidemic drug therapy
has exact synonym: antilipemic therapy
has exact synonym: antilipidemic agent therapy
has exact synonym: antilipidemic drug treatment therapy
has exact synonym: dyslipidemia agent therapy
has exact synonym: dyslipidemia drug treatment therapy
has exact synonym: dyslipidemic agent drug treatment
has exact synonym: dyslipidemic drug therapy
has exact synonym: dyslipidemic drugs therapy
has exact synonym: hypolipidemic agent therapy
has exact synonym: lipid-lowering agent therapy
has exact synonym: treatment with anti-lipidemic agent
has exact synonym: treatment with anti-lipidemic drug
has exact synonym: treatment with anti-lipidemic medication
has exact synonym: treatment with antilipemic drug
has exact synonym: treatment with antilipidemic agent
has exact synonym: treatment with antilipidemic medication
has exact synonym: treatment with dyslipidemic agent
has exact synonym: treatment with dyslipidemic drug
has exact synonym: treatment with dyslipidemic medication

RAAS inhibitor therapy
type: Class
subclass of: cardiovascular agent therapy
IAO_0000115: Treatment with Renin-angiotensin-aldosterone system (RAAS) inhibitors, a group of drugs that act by inhibiting the renin-angiotensin-aldosterone system and include angiotensin-converting enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), and direct renin inhibitors
date: 2019-01-22T18:19:47Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Treatment with RAAS inhibitor
has exact synonym: renin-angiotensin-aldosterone system inhibitor therapy
has exact synonym: treatment with renin-angiotensin-aldosterone system inhibitor

vasodilator agent therapy
type: Class
subclass of: cardiovascular agent therapy
IAO_0000115: A therapy using a drug to cause dilation of the blood vessels.
date: 2019-01-22T18:20:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35620
has db xref: NCIT:C29707
has exact synonym: vasodilating agent therapy
has exact synonym: vasodilating drug treatment therapy
has exact synonym: vasodilator agent therapy
has exact synonym: vasodilator drug therapies
has exact synonym: vasodilator drug therapy
has exact synonym: vasodilator drug treatment therapy
has exact synonym: vasodilator therapies

Axiom
annotated source: vasodilator agent therapy
annotated property: IAO_0000115
annotated target: A therapy using a drug to cause dilation of the blood vessels.
has db xref: CHEBI:35620

obsolete other cardiovascular agent therapy
type: Class
IAO_0100001: cardiovascular agent therapy
deprecated: true

non-opioid analgesic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35481
subclass of: analgesic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35481
IAO_0000115: Use of a drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
date: 2019-01-22T18:22:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35481
has exact synonym: non-narcotic analgesic agent therapy
has exact synonym: non-narcotic analgesic drug therapy
has exact synonym: non-narcotic analgesic medication treatement
has exact synonym: non-opioid analgesic agent therapy
has exact synonym: non-opioid analgesics drug therapy
has exact synonym: non-opioid analgesics medication therapy
has exact synonym: non-opioid analgesics medication treatment
has exact synonym: non-opioid analgesics therapy
has exact synonym: treatment with non-narcotic analgesic

opioid analgesic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35482
subclass of: analgesic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35482
IAO_0000115: Use of a narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
date: 2019-01-22T18:22:42Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: narcotic therapy
has db xref: CHEBI:35482
has exact synonym: narcotic analgesic medication therapy
has exact synonym: narcotic analgesic medication treatment
has exact synonym: narcotic analgesic therapy
has exact synonym: opioid analgesic drug therapy
has exact synonym: opioid analgesic medication therapy
has exact synonym: opioid analgesic medication treatment
has exact synonym: opioid analgesics
has exact synonym: opioid therapy
has exact synonym: treatment with opioid analgesic

local anaesthetic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_36333
subclass of: anesthetic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_36333
IAO_0000115: Treatment with any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
date: 2019-01-22T18:24:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:36333
has exact synonym: local anaesthesia therapy
has exact synonym: local anaesthetic medication therapy
has exact synonym: local anaesthetics therapy
has exact synonym: local anesthesia therapy
has exact synonym: local anesthesia treatment
has exact synonym: local anesthetic agent therapy
has exact synonym: local anesthetics therapy
has exact synonym: treatment with local anaesthetic
has narrow synonym: epidural therapy
has narrow synonym: spinal block therapy
has narrow synonym: topical anesthesia therapy
has narrow synonym: topical anesthetic therapy

aminoglycoside agent therapy
type: Class
subclass of: antibacterial agent therapy
IAO_0000115: An antibacterial substance with aminoglycoside structure.
date: 2019-01-22T18:25:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:47779
has exact synonym: aminoglycoside drug therapy
has exact synonym: aminoglycoside drug treatment
has exact synonym: aminoglycosides therapy

Axiom
annotated source: aminoglycoside agent therapy
annotated property: IAO_0000115
annotated target: An antibacterial substance with aminoglycoside structure.
has db xref: http://orcid.org/0000-0001-7941-2961

cephalosporin agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_23066
subclass of: beta-lactam antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_23066
IAO_0000115: Use of a class of beta-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring.
date: 2019-01-22T18:25:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:23066
has exact synonym: cephalosporin antibacterial agent therapy
has exact synonym: cephalosporin beta-lactam therapy
has exact synonym: cephalosporin drug therapy
has exact synonym: cephalosporin drug treatment
has exact synonym: cephalosporin therapies
has exact synonym: cephalosporin treatment
has exact synonym: cephalosporins therapy
has exact synonym: treatment with cephalosporin agent
has exact synonym: treatment with cephalosporin antibacterial drug
has exact synonym: treatment with cephalosporin antibacterial medication
has exact synonym: treatment with cephalosporin antibiotic drug
has exact synonym: treatment with cephalosporin antibiotic medication
comment: Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy.
comment: treatment with cephalosporin drug
comment: treatment with cephalosporin medication

Axiom
annotated source: cephalosporin agent therapy
annotated property: comment
annotated target: Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy.
has db xref: CHEBI:23066

penicillin agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_17334
subclass of: beta-lactam antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_17334
IAO_0000115: Use of an antibacterial substance with penicillin structure.
date: 2019-01-22T18:26:03Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:17334
has exact synonym: penicillin antibacterial therapy
has exact synonym: penicillin antibacterial treatment
has exact synonym: penicillin beta-lactam therapy
has exact synonym: penicillin drug therapy
has exact synonym: penicillin drug treatment
has exact synonym: penicillin treatment
has exact synonym: treatment with a penicillin agent
has exact synonym: treatment with a penicillin drug
has exact synonym: treatment with a penicillin medication
has exact synonym: treatment with a penicillin therapy
has exact synonym: treatment with penicillin antibacterial drug
has exact synonym: treatment with penicillin antibacterial medication
has exact synonym: treatment with penicillin antibiotic agent
has exact synonym: treatment with penicillin antibiotic drug
has exact synonym: treatment with penicillin antibiotic medication
has exact synonym: treatment with penicillin antibiotic therapy

obsolete other beta-lactams
type: Class
IAO_0100001: beta-lactam antibacterial agent therapy
deprecated: true

macrolide antibacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_25105
subclass of: antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_25105
IAO_0000115: Use of a drug with a macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity.
date: 2019-01-22T18:26:31Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: macrolides
has db xref: CHEBI:25105
has exact synonym: Treatment with a macrolide antibacterial agent
has exact synonym: Treatment with a macrolide antibacterial drug
has exact synonym: Treatment with a macrolide antibacterial medication
has exact synonym: Treatment with a macrolide antibiotic agent
has exact synonym: Treatment with a macrolide antibiotic drug
has exact synonym: Treatment with a macrolide antibiotic medication
has exact synonym: macrolide antibacterial drug therapy
has exact synonym: macrolide antibacterial therapy
has exact synonym: macrolide drug therapy
has exact synonym: macrolide drug treatment

quinolone antibacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_86324
subclass of: antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_86324
IAO_0000115: Use of an organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton.
date: 2019-01-22T18:26:50Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: quinolones
has db xref: CHEBI:86324
has exact synonym: quinolone antibacterial therapy
has exact synonym: quinolone antibiotic agent treatment
has exact synonym: treatment with quinolone antibacterial agent
has exact synonym: treatment with quinolone antibacterial drug
has exact synonym: treatment with quinolone antibacterial medication
has exact synonym: treatment with quinolone antibiotic agent
has exact synonym: treatment with quinolone antibiotic drug
has exact synonym: treatment with quinolone antibiotic medication

sulfonamide antibacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_87228
subclass of: antibacterial agent therapy
subclass of: inflammatory bowel disease agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_87228
IAO_0000115: Use of a class of sulfonamides whose members generally have bacteriostatic antibiotic properties.
date: 2019-01-22T18:27:30Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: sulfonamides therapy
has db xref: CHEBI:87228
has exact synonym: sulfonamide antibacterial drug therapy
has exact synonym: sulfonamide antibacterial therapy
has exact synonym: sulfonamide antibiotic therapy
has exact synonym: sulfonamide drug therapy
has exact synonym: sulfonamide drug treatment
has exact synonym: treatment with a sulfonamide antibacterial drug
has exact synonym: treatment with a sulfonamide antibacterial medication
has exact synonym: treatment with a sulfonamide antibiotic agent
has exact synonym: treatment with a sulfonamide antibiotic drug
has exact synonym: treatment with a sulfonamide antibiotic medication
has exact synonym: treatment with a sulfonamide antibiotic therapy

tetracycline therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_27902
subclass of: antibacterial agent therapy
subclass of: antiprotozoal agent therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_27902
IAO_0000115: Treatment with a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.
date: 2019-01-22T18:28:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:27902
has exact synonym: tetracycline antibiotic therapy
has exact synonym: tetracycline drug therapy
has exact synonym: tetracycline drug treatment
has exact synonym: treatment with a tetracycline antibacterial agent
has exact synonym: treatment with a tetracycline antibacterial drug
has exact synonym: treatment with a tetracycline antibacterial medication
has exact synonym: treatment with a tetracycline antibacterial therapy
has exact synonym: treatment with a tetracycline antibiotic agent
has exact synonym: treatment with a tetracycline antibiotic drug
has exact synonym: treatment with a tetracycline antibiotic medication
has exact synonym: treatment with a tetracycline antibiotic therapy

obsolete other antibacterial agents
type: Class
IAO_0100001: antibacterial agent therapy
deprecated: true

calcium channel modifying agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38808
subclass of: anticonvulsant agent therapy
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38808
IAO_0000115: Treatment with a drug that can regulate intracellular calcium levels.
date: 2019-01-22T18:28:49Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38808
has exact synonym: calcium channel modifier drug therapy
has exact synonym: treatment with calcium channel modifying agent
has exact synonym: treatment with calcium channel modifying medication
has exact synonym: treatment with calcium channel modulator

GABA augmenting agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_51374
subclass of: anticonvulsant agent therapy
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_51374
IAO_0000115: Treatment with a substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
date: 2019-01-22T18:29:21Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:51374
has exact synonym: GABA augmenting therapy
has exact synonym: gamma-aminobutyric acid drug therapy
has exact synonym: gamma-aminobutyric acid modulating agent therapy
has exact synonym: treatment with GABA agent
has exact synonym: treatment with GABA drug
has exact synonym: treatment with GABA medication
has exact synonym: treatment with gamma-aminobutyric acid augmenting agent
has exact synonym: treatment with gamma-aminobutyric acid augmenting drug
has exact synonym: treatment with gamma-aminobutyric acid augmenting medication

glutamate reducing agent therapy
type: Class
subclass of: glutamatergic pathway modifying agent therapy
IAO_0000115: Treatment with an agent which decreases glutamate.
date: 2019-01-22T18:29:56Z
creator: http://orcid.org/0000-0001-7941-2961

sodium channel inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38633
subclass of: anticonvulsant agent therapy
subclass of: molecular pathway modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38633
IAO_0000115: Use of a drug that inhibits sodium influx through cell membranes.
date: 2019-01-22T18:30:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38633
has exact synonym: Na+ channel blocker therapy
has exact synonym: Na+ channel inhibitor drug therapy
has exact synonym: sodium channel blocker drug therapy
has exact synonym: sodium channel inhibitor drug therapy
has exact synonym: treatment with Na+ channel inhibitor
has exact synonym: treatment with sodium channel antagonist
has exact synonym: treatment with sodium channel blocker
has exact synonym: treatment with sodium channel inhibitor

obsolete anticonvulsants, other
type: Class
IAO_0100001: anticonvulsant agent therapy
deprecated: true

cholinesteriase inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37733
subclass of: antidementia agent therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_37733
IAO_0000115: They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system.
date: 2019-01-22T18:32:56Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:37733
has exact synonym: cholinesterase inhibitor drug treatment
has exact synonym: cholinesterase inhibitor medication therapy
has exact synonym: treatment with EC 3.1.1.8 (cholinesterase) inhibitor
comment: Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy.

Axiom
annotated source: cholinesteriase inhibitor therapy
annotated property: IAO_0000115
annotated target: They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system.
has db xref: PMID:31335056

Axiom
annotated source: cholinesteriase inhibitor therapy
annotated property: comment
annotated target: Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy.
has db xref: PMID:31335056

glutamatergic pathway modifying agent therapy
type: Class
subclass of: antidementia agent therapy
subclass of: molecular pathway modifying agent therapy
IAO_0000115: Treatment with an agent which modifies glutamate.
date: 2019-01-22T18:33:33Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: glutamate modulator therapy
has exact synonym: glutamate pathway modifying drug treatment
has exact synonym: glutamatergic drug therapy
has exact synonym: glutamatergic drug treatment

obsolete antidementia agents, other
type: Class
IAO_0100001: antidementia agent therapy
deprecated: true

monoamine oxidase inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38623
subclass of: antidepressant agent therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38623
IAO_0000115: A drug that acts as an inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
date: 2019-01-22T18:36:08Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38623
has db xref: NCIT:C667
has exact synonym: MAO drug therapy
has exact synonym: MAO drug treatment
has exact synonym: MAO inhibitor therapy
has exact synonym: MAOI therapy
has exact synonym: inhibitors of MAO therapy
has exact synonym: inhibitors of monoamine oxidase therapy
has exact synonym: treatment with EC 1.4.3.4 (monoamine oxidase) inhibitor
comment: Any substance that inhibits monoamine oxidase (MAO), an enzyme that catalyzes the oxidative deamination of monoamines and plays a role in the inactivation of neurotransmitters.

Axiom
annotated source: monoamine oxidase inhibitor therapy
annotated property: hasExactSynonym
annotated target: MAO inhibitor therapy
has synonym type: OMO_0003000

Axiom
annotated source: monoamine oxidase inhibitor therapy
annotated property: hasExactSynonym
annotated target: MAOI therapy
has related synonym: OMO_0003000

Axiom
annotated source: monoamine oxidase inhibitor therapy
annotated property: comment
annotated target: Any substance that inhibits monoamine oxidase (MAO), an enzyme that catalyzes the oxidative deamination of monoamines and plays a role in the inactivation of neurotransmitters.
has db xref: NCIT:C667

serotonin-norepinephrine reuptake inhibitor agent therapy
type: Class
subclass of: antidepressant agent therapy
IAO_0000115: Treatment with a medication that increases the extracellular level of the neurotransmitter serotonin (5-HT) and norepinephrine by inhibiting their reuptake into the presynaptic cell.
date: 2019-01-22T18:40:17Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: OMIT:0001323
has exact synonym: SNRI agent therapy
has exact synonym: SNRI drug therapy
has exact synonym: SNRI drug treatment
has exact synonym: serotonin and noradrenaline reuptake inhibitor agent therapy
has exact synonym: serotonin and noradrenaline reuptake inhibitor drug therapy
has exact synonym: serotonin and noradrenaline reuptake inhibitor drug treatment
has exact synonym: serotonin and norepinephrine reuptake inhibitor therapy
has exact synonym: serotonin-noradrenaline reuptake inhibitor agent therapy
has exact synonym: serotonin-noradrenaline reuptake inhibitor drug treatment
has exact synonym: serotonin-norepinephrine reuptake inhibitor drug treatment

tricyclic antidepressant agent therapy
type: Class
subclass of: antidepressant agent therapy
IAO_0000115: Treatment with mood-stimulating agents which contain a tricyclic structure and are used primarily in the treatment of affective disorders and related conditions.
date: 2019-01-22T18:41:18Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C94727
has exact synonym: tricyclic antidepressant drug therapy
has exact synonym: tricyclic antidepressant drug treatment

obsolete antidepressants, other
type: Class
IAO_0100001: antidepressant agent therapy
deprecated: true

antidote agent therapy
type: Class
subclass of: therapeutic antidotes, deterrents, and toxicologic agent therapy
IAO_0000115: Treatment with a therapeutic substance used to counteract the toxic action(s) of a specified xenobiotic.
date: 2019-01-22T18:41:49Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50247
has exact synonym: antidote drug therapy

Axiom
annotated source: antidote agent therapy
annotated property: IAO_0000115
annotated target: Treatment with a therapeutic substance used to counteract the toxic action(s) of a specified xenobiotic.
has db xref: PMID:9079217

abuse deterrent agent therapy
type: Class
subclass of: therapeutic antidotes, deterrents, and toxicologic agent therapy
IAO_0000115: Medication given to prevent or deter a patient from using a substance.
date: 2019-01-22T18:42:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: abuse deterrent drug treatment

toxicologic agent therapy
type: Class
subclass of: therapeutic antidotes, deterrents, and toxicologic agent therapy
IAO_0000115: An agent used to treat a toxicologic agent.
date: 2019-01-22T18:42:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: toxicologic drug therapy

glucocorticicoid agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_24261
subclass of: inflammatory bowel disease agent therapy
subclass of: anti-asthmatic agent therapy
subclass of: corticosteroid agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_24261
IAO_0000115: Treatment with a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
date: 2019-01-22T18:44:08Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:24261
has exact synonym: treatment with a glucocorticoid drug
has exact synonym: treatment with a glucocorticoid medication
has exact synonym: treatment with a glucocorticoid therapy

Axiom
annotated source: glucocorticicoid agent therapy
annotated property: IAO_0000115
annotated target: Treatment with a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
has db xref: CHEBI:24261

NSAID therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35475
subclass of: antirheumatic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35475
IAO_0000115: Treatment with an anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
date: 2019-01-22T18:44:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35475
has exact synonym: non-steroidal anti-inflammatory medication treatment
has exact synonym: treatment with NSAID drug
has exact synonym: treatment with NSAID medication
has exact synonym: treatment with NSAID therapy
has exact synonym: treatment with non-steroidal anti-inflammatory drug
has exact synonym: treatment with non-steroidal anti-inflammatory medication

antimigraine agent therapy
type: Class
subclass of: central nervous system agent therapy
IAO_0000115: Treatment with medications to alleviate symptoms and occurrence of migraine headaches.
date: 2019-01-22T18:45:01Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti migraine drug therapy
has exact synonym: anti-migraine drug therapy
has exact synonym: anti-migraine medication therapy
has exact synonym: migraine headache therapy
has exact synonym: migraine medication treatment
has exact synonym: migraine treatment
has exact synonym: standard migraine therapies
has exact synonym: treatment for migraine
has exact synonym: treatment of migraine
has exact synonym: treatment with antimigraine agent

Axiom
annotated source: antimigraine agent therapy
annotated property: IAO_0000115
annotated target: Treatment with medications to alleviate symptoms and occurrence of migraine headaches.
has db xref: https://orcid.org/0000-0001-7941-2961

abortive antimigraine agent therapy
type: Class
subclass of: antimigraine agent therapy
IAO_0000115: Use of medication to treat migraine headache symptoms acutely.
date: 2019-01-22T18:45:12Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: abortive anti migraine medication therapy
has exact synonym: abortive anti-migraine drug therapy
has exact synonym: abortive migraine headache treatment
has exact synonym: abortive migraine medication therapy
has exact synonym: abortive migraine treatment
has exact synonym: abortive therapy for migraine headache
has exact synonym: abortive treatment of migraine
has exact synonym: standard migraine abortive therapies
has exact synonym: symptomatic treatment of migraine
has exact synonym: treatment with abortive antimigraine agent

Axiom
annotated source: abortive antimigraine agent therapy
annotated property: IAO_0000115
annotated target: Use of medication to treat migraine headache symptoms acutely.
has db xref: https://orcid.org/0000-0001-7941-2961

prophylactic antimigraine agent therapy
type: Class
subclass of: antimigraine agent therapy
IAO_0000115: Use of medication to decrease the occurrence of migraine headaches.
date: 2019-01-22T18:45:30Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: prophylactic migraine headache treatment
has exact synonym: prophylactic migraine therapy
has exact synonym: prophylactic migraine treatment
has exact synonym: prophylactic treament of migraine headache
has exact synonym: prophylactic treatment of migraine
has exact synonym: treatment with prophylactic antimigraine agent

Axiom
annotated source: prophylactic antimigraine agent therapy
annotated property: IAO_0000115
annotated target: Use of medication to decrease the occurrence of migraine headaches.
has db xref: https://orcid.org/0000-0001-7941-2961

antimyasthenic agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Medication given by mouth or by injection to treat myasthenia gravis.
date: 2019-01-22T18:47:33Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti-myasthenic drug therapy
has exact synonym: antimyasthenic drug therapy
has exact synonym: antimyasthenic medication therapy

parasympathomimetic therapy
type: Class
subclass of: antimyasthenic agent therapy
IAO_0000115: Treatment with a drug to activate the parasympathetic nervous system (PSNS). They can act as direct agonists of acetylcholine receptors (ACh) or indirect agonists of ACh. While direct agonists act by binding directly to muscarinic or nicotinic ACh receptors, indirect agonists prolong the action of endogenous acetylcholine by inhibiting acetylcholinesterase.
date: 2019-01-22T18:47:49Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: cholinomimetic agents therapy
has exact synonym: cholinomimetic drug therapy
has exact synonym: cholinomimetic medication therapy
has exact synonym: parasympathomimetic agent therapy
has exact synonym: parasympathomimetic drug therapy
has exact synonym: parasympathomimetic drug treatment
has exact synonym: parasympathomimetic medication therapy
has exact synonym: treatment with cholinomimetic agent
has exact synonym: treatment with cholinomimetic drug
has exact synonym: treatment with cholinomimetic medication
has exact synonym: treatment with parasympathomimetic agent
has exact synonym: treatment with parasympathomimetic drug
has exact synonym: treatment with parasympathomimetic medication
comment: Direct agonists of ACh are used topically in ophthalmology to induce miosis, while indirect agonists are used to treat, e.g., postoperative ileus or urinary retention and myasthenia gravis.

antimycobacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64912
subclass of: antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64912
IAO_0000115: Use of a treat or prevent infections caused by Mycobacteria, a genus of actinobacteria.
date: 2019-01-22T18:48:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64912
has exact synonym: antimycobacterial drug treatment
has exact synonym: antimycobacterials therapy
has exact synonym: antimycobacterium therapy
has exact synonym: treatment with an anti-mycobacterial agent
has exact synonym: treatment with an anti-mycobacterial drug
has exact synonym: treatment with an anti-mycobacterial medication
has exact synonym: treatment with an anti-mycobacterial therapy
has exact synonym: treatment with an antimycobacterial agent
has exact synonym: treatment with an antimycobacterial drug
has exact synonym: treatment with an antimycobacterial medication
has exact synonym: treatment with antimycobacterial drug

antitubercular agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_33231
subclass of: antimycobacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_33231
IAO_0000115: Use of a substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
date: 2019-01-22T18:49:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:33231
has exact synonym: antitubercular drug therapy
has exact synonym: antitubercular drug treatment
has exact synonym: antituberculosis agent therapy
has exact synonym: treatment with an anti-tubercular agent
has exact synonym: treatment with an anti-tubercular drug
has exact synonym: treatment with an anti-tubercular medication
has exact synonym: treatment with an anti-tubercular therapy
has exact synonym: treatment with an antitubercular agent
has exact synonym: treatment with an antitubercular drug
has exact synonym: treatment with an antitubercular medication
has exact synonym: treatment with antitubercular agent
has narrow synonym: tuberculostatic agent therapy

leprostatic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35816
subclass of: antimycobacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35816
IAO_0000115: Use of a substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
date: 2019-01-22T18:49:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35816
has exact synonym: leprostatic drug treatment
has exact synonym: treatment with a leprostatic agent
has exact synonym: treatment with a leprostatic drug
has exact synonym: treatment with a leprostatic medication
has exact synonym: treatment with a leprostatic therapy
has exact synonym: treatment with leprostatic drug

alkylating agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_22333
subclass of: antineoplastic therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_22333
IAO_0000115: An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.
date: 2019-01-22T18:50:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:22333
has db xref: NCIT:C1590
has db xref: NCIT:C223
has exact synonym: alkylating drug therapy
has exact synonym: anti-neoplastic alkylating agent therapy
has exact synonym: antineoplastic alkylating agent therapy
has exact synonym: treatment with alkylating agent
has exact synonym: treatment with alkylating drug
has exact synonym: treatment with alkylating medication
comment: Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.

Axiom
annotated source: alkylating agent therapy
annotated property: IAO_0000115
annotated target: An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.
has db xref: NCIT:C1590

Axiom
annotated source: alkylating agent therapy
annotated property: comment
annotated target: Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
has db xref: CHEBI:22333

antiangiogenic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48422
subclass of: antineoplastic therapy
subclass of: angiogenesis modulating agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48422
IAO_0000115: Use of an agent or endogenous substance that inhibits the formation of capillaries from existing blood vessels.
date: 2019-01-22T18:50:46Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48422
has db xref: NCIT:C1742
has exact synonym: angiogenesis antagonist therapy
has exact synonym: angiogenesis blocker therapy
has exact synonym: anti-angiogenic agent therapy
has exact synonym: antiangiogenesis agent therapy
has exact synonym: antiangiogenic agent drug treatment
has exact synonym: treatment with angiogenesis antagonist agent
has exact synonym: treatment with angiogenesis antagonist drug
has exact synonym: treatment with angiogenesis antagonist medication
has exact synonym: treatment with angiogenesis blocker agent
has exact synonym: treatment with angiogenesis blocker drug
has exact synonym: treatment with angiogenesis blocker medication
has exact synonym: treatment with angiogenesis inhibitor
has exact synonym: treatment with angiogenesis inhibitor agent
has exact synonym: treatment with angiogenesis inhibitor drug
has exact synonym: treatment with angiogenesis inhibitor medication
has exact synonym: treatment with anti-angiogenic agent
has exact synonym: treatment with anti-angiogenic drug
has exact synonym: treatment with anti-angiogenic medication
has exact synonym: treatment with antiangiogenic agent
has exact synonym: treatment with antiangiogenic drug
has exact synonym: treatment with antiangiogenic medication
has narrow synonym: angiostatic agent therapy

obsolete antiestrogen agent therapy
type: Class
IAO_0100001: anti-estrogen agent therapy
deprecated: true

antimetabolite agent therapy
type: Class
subclass of: antineoplastic therapy
IAO_0000115: Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis.
date: 2019-01-22T18:51:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15183
has exact synonym: anti-metabolite agent drug treatment
has exact synonym: antimetabolite agent drug treatment
has exact synonym: antimetabolite cancer drug
has exact synonym: antimetabolite cancer medication
has exact synonym: antimetabolites therapy
has exact synonym: cancer drug antimetabolite
has exact synonym: treatment with anti-metabolite agent
has exact synonym: treatment with anti-metabolite drug
has exact synonym: treatment with anti-metabolite medication
has exact synonym: treatment with antimetabolite agent
has exact synonym: treatment with antimetabolite drug
has exact synonym: treatment with antimetabolite medication

Axiom
annotated source: antimetabolite agent therapy
annotated property: IAO_0000115
annotated target: Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis.
has db xref: NCIT:C15183

aromatase inhibitor agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50790
subclass of: antineoplastic therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50790
IAO_0000115: Treatment with an EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.
date: 2019-01-22T18:54:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50790
has exact synonym: aromatase inhibitor drug therapy
has exact synonym: aromatase inhibitor drug treatment
has exact synonym: treatment with EC 1.14.14.14 (aromatase) inhibitor
has exact synonym: treatment with aromatase inhibitor agent
has exact synonym: treatment with aromatase inhibitor drug
has exact synonym: treatment with aromatase inhibitor medication
has exact synonym: treatment with estrogen synthetase inhibitor agent
has exact synonym: treatment with estrogen synthetase inhibitor drug
has exact synonym: treatment with estrogen synthetase inhibitor medication
has exact synonym: treatment with estrogen synthetase inhibitor therapy
has exact synonym: treatment with oestrogen synthetase inhibitor agent
has exact synonym: treatment with oestrogen synthetase inhibitor drug
has exact synonym: treatment with oestrogen synthetase inhibitor medication

antineoplastic molecular target inhibitor agent therapy
type: Class
subclass of: antineoplastic therapy
subclass of: enzyme inhibitor agent therapy
IAO_0000115: A treatment that uses drugs to target specific genes and proteins that are involved in the growth and survival of cancer cells.
date: 2019-01-22T18:55:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: antineoplastic molecular target inhibitor drug treatment
has exact synonym: cancer targeted inhibitor drug treatment
has exact synonym: cancer targeted inhibitor therapy
has exact synonym: targeted cancer drug therapy
has exact synonym: targeted cancer therapy
has exact synonym: treatment with targeted cancer drug
has exact synonym: treatment with targeted cancer medication
has exact synonym: treatment with targeted cancer therapy

antineoplastic monoclonal antibody agent therapy
type: Class
subclass of: biologic therapy
subclass of: antineoplastic therapy
IAO_0000115: Treatment with a biological agent (monoclonal antibody) that target factors responsible for deregulated cell proliferation as in cancer.
date: 2019-01-22T18:55:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15490
has exact synonym: antineoplastic monoclonal antibodies therapy
has exact synonym: antineoplastic monoclonal antibody drug treatment

retinoid agent therapy
type: Class
subclass of: antineoplastic therapy
subclass of: anti-inflammatory agent therapy
subclass of: dermatological agent therapy
IAO_0000115: Use of any of a group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities.
date: 2019-01-22T18:56:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C804
has exact synonym: retinoic acid agent therapy
has exact synonym: retinoic acid drug therapy
has exact synonym: retinoid drug therapy
has exact synonym: retinoid drug treatment
has exact synonym: treatment with retinoic acid agent
has exact synonym: treatment with retinoic acid drug
has exact synonym: treatment with retinoic acid medication
has exact synonym: treatment with retinoic acid therapy
has exact synonym: treatment with retinoid agent
has exact synonym: treatment with retinoid drug
has exact synonym: treatment with retinoid medication
has exact synonym: treatment with retinoid therapy
comment: A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization.

anthelmintic agent therapy
type: Class
subclass of: antiparasititic agent therapy
IAO_0000115: Substance intended to kill parasitic worms (helminths).
date: 2019-01-22T18:57:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35443
has exact synonym: anthelminitic agent drug therapy
has exact synonym: anthelmintic drug therapy
has exact synonym: anthelmintic drug treatment
has exact synonym: antihelminthics
has exact synonym: vermifuge therapy
has narrow synonym: vermicide therapy

Axiom
annotated source: anthelmintic agent therapy
annotated property: IAO_0000115
annotated target: Substance intended to kill parasitic worms (helminths).
has db xref: CHEBI:35443

antiprotozoal agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35820
subclass of: antiparasititic agent therapy
subclass of: antimicrobial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35820
IAO_0000115: Treatment with an antimicrobial drug which is used to treat or prevent protozoal infections.
date: 2019-01-22T18:57:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35820
has exact synonym: antiprotozoal drug treatment
has exact synonym: antiprotozoals therapy
has exact synonym: treatment with an antiprotozoal agent
has exact synonym: treatment with an antiprotozoal drug
has exact synonym: treatment with an antiprotozoal medication
has exact synonym: treatment with antiprotozoal drug
has related synonym: protozoan drug treatment

ectoparasiticide agent therapy
type: Class
subclass of: antiparasititic agent therapy
IAO_0000115: An agent used to as a treament of ectoparasitic infestations.
date: 2019-01-22T18:58:53Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38956
has exact synonym: ectoparasiticide therapy

Axiom
annotated source: ectoparasiticide agent therapy
annotated property: IAO_0000115
annotated target: An agent used to as a treament of ectoparasitic infestations.
has db xref: https://orcid.org/0000-0001-7941-2961

anti-cytomegalovirus agent therapy
type: Class
subclass of: antiviral agent therapy
IAO_0000115: Treatment with an antiviral drug used for treatment of cytomegalovirus infection.
date: 2019-01-22T18:59:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Anti-CMV agent therapy
has exact synonym: anti-CMV medication reatment
has exact synonym: anti-cmv drug therapy
has exact synonym: anti-cmv therapy
has exact synonym: anti-cytomegalovirus drug therapy
has exact synonym: anti-cytomegalovirus drug treatment
has exact synonym: anti-cytomegalovirus medication treatment
has exact synonym: antiviral treatment of cytomegalovirus therapy
has exact synonym: cytomegalovirus drug treatment therapy

Axiom
annotated source: anti-cytomegalovirus agent therapy
annotated property: IAO_0000115
annotated target: Treatment with an antiviral drug used for treatment of cytomegalovirus infection.
has db xref: PMID:21827432

atypical antipsychotic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_65191
subclass of: antipsychotic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_65191
IAO_0000115: Treatment with a drug which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
date: 2019-01-22T19:00:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:65191
has exact synonym: atypical antipsychotic agent treatment
has exact synonym: atypical antipsychotic drug treatment
has exact synonym: second generation antipsychotic agent therapy
has exact synonym: second generation antipsychotic drug treatment
has exact synonym: treatment with atypical antipsychotic
has exact synonym: treatment with second generation antipsychotic

conventional antipsychotic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_65190
subclass of: antipsychotic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_65190
IAO_0000115: Treatment with a drug which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
date: 2019-01-22T19:01:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:65190
has exact synonym: conventional antipsychotic drug treatment
has exact synonym: first generation antipsychotic agent treatment
has exact synonym: first generation antipsychotic drug treatment
has exact synonym: treatment with conventional antipsychotic
has exact synonym: treatment with first generation antipsychotic
has exact synonym: typical antipsychotic agent therapy
has exact synonym: typical antipsychotic drug treatment
has exact synonym: typical antipsychotic therapy

antispasticity agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with an agent that suppresses muscle spasms.
date: 2019-01-22T19:02:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:53784
has exact synonym: anti-spasticity agent therapy
has exact synonym: antispasmodic agent therapy
has exact synonym: antispasmodic drug therapy
has exact synonym: antispastic agent therapy
has exact synonym: antispastic drug treatment
has exact synonym: antispasticity agent drug treatment
has exact synonym: antispasticity drug therapy
has exact synonym: treatmeant with antispasticity drug
has exact synonym: treatmeant with antispasticity medication
has exact synonym: treatment with a antispasmodic drug
has exact synonym: treatment with a antispasmodic medication
has exact synonym: treatment with a antispasmodic therapy
has exact synonym: treatment with antispasticity agent

antihepatitis agent therapy
type: Class
subclass of: antiviral agent therapy
IAO_0000115: Use of a drug for the treatment and prophylaxis of infection with hepatitis virus(es).
date: 2019-01-22T20:15:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti-hepatitis agent therapy
has exact synonym: anti-hepatitis drug therapy
has exact synonym: anti-hepatitis drug treatment
has exact synonym: antihepatitis drug therapy
has exact synonym: antihepatitis drug treatment
has exact synonym: treatment with anti-hepatitis drug
has exact synonym: treatment with anti-hepatitis medication
has exact synonym: treatment with antihepatitis medication

antiherpetic agent therapy
type: Class
subclass of: antiviral agent therapy
IAO_0000115: Use of any drug that counters herpes.
date: 2019-01-22T20:15:33Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti-herpes agent therapy
has exact synonym: anti-herpes drug therapy
has exact synonym: anti-herpes medication therapy
has exact synonym: antiherpetic agent drug therapy
has exact synonym: antiherpetic agent drug treatment
has exact synonym: treatment with anti-herpes agent
has exact synonym: treatment with anti-herpes drug
has exact synonym: treatment with antiherpetic agent
has exact synonym: treatment with antiherpetic drug
has exact synonym: treatment with antiherpetic medication

anti-HIV agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64946
subclass of: antiviral agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64946
IAO_0000115: Treatment with an antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
date: 2019-01-22T20:16:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64946
has db xref: NCIT:C1660
has exact synonym: anti-HIV drug treatment
has exact synonym: treatment with anti-HIV agent
has exact synonym: treatment with anti-HIV drug
has exact synonym: treatment with anti-human immunodeficiency virus agent
has exact synonym: treatment with anti-human immunodeficiency virus drug
has exact synonym: treatment with anti-human immunodeficiency virus medication

anti-HIV therapy, fusion inhibitor
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_59886
subclass of: anti-HIV agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_59886
IAO_0000115: Treatment with a drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS.
date: 2019-01-22T20:18:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:59886
has exact synonym: anti-HIV theraoym fusion inhibitor drug treatment
has exact synonym: anti-HIV therapy, fusion inhibitor drug
has exact synonym: treatment with HIV fusion inhibitor
has exact synonym: treatment with HIV fusion inhibitor agent
has exact synonym: treatment with HIV fusion inhibitor drug
has exact synonym: treatment with HIV fusion inhibitor medication
has exact synonym: treatment with HIV fusion inhibitor therapy

non-nucleoside reverse transcriptase inhibitor therapy
type: Class
subclass of: anti-HIV agent therapy
IAO_0000115: Treatment with a substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication.
date: 2019-01-22T20:18:58Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C97453
has exact synonym: anti-HIV non-nucleoside reverse transcriptase inhibitor drug therapy
has exact synonym: anti-HIV non-nucleoside reverse transcriptase inhibitor drug treatment
has exact synonym: treatment with anti-HIV therapy, non-nucleoside reverse transcriptase inhibitor agent
has exact synonym: treatment with anti-HIV therapy, non-nucleoside reverse transcriptase inhibitor drug
has exact synonym: treatment with anti-HIV therapy, non-nucleoside reverse transcriptase inhibitor medication

nucleoside and nucleotide reverse transcriptase inhibitor therapy
type: Class
subclass of: anti-HIV agent therapy
IAO_0000115: Treatment with nucleoside reverse transcriptase inhibitors (NRTIs) which block reverse transcriptase (an HIV enzyme).
date: 2019-01-22T20:20:58Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: NRTI drug therapy
has exact synonym: anti-HIV nucleoside and nucleotide reverse transcriptase inhibitor drug treatment
has exact synonym: treatment with NRTI agent
has exact synonym: treatment with NRTI drug
has exact synonym: treatment with NRTI medication
has exact synonym: treatment with nucleoside and nucleotide reverse transcriptase inhibitor medication
has exact synonym: treatment with nucleoside-nucleotide reverse transcriptase inhibitor drug
has exact synonym: treatment with nucleoside-nucleotide reverse transcriptase inhibitor medication
has exact synonym: treatment with nucleoside/nucleotide reverse transcriptase inhibitor drug
has exact synonym: treatment with nucleoside/nucleotide reverse transcriptase inhibitor medication

HIV protease inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35660
subclass of: anti-HIV agent therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35660
IAO_0000115: Use of an inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
date: 2019-01-22T20:21:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35660
has db xref: NCIT:C97366
has exact synonym: HIV protease inhibitor drug therapy
has exact synonym: HIV protease inhibitor drug treatment
has exact synonym: treatment with HIV protease inhibitor
has exact synonym: treatment with HIV protease inhibitor agent
has exact synonym: treatment with HIV protease inhibitor drug
has exact synonym: treatment with HIV protease inhibitor medication

anti-influenza agent therapy
type: Class
subclass of: antiviral agent therapy
IAO_0000115: Treatment with a drug used for the treatment and prophylaxis of infection with influenza viruses.
date: 2019-01-22T20:21:48Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti-flu medication therapy
has exact synonym: anti-influenza drug therapy
has exact synonym: anti-influenza drug treatment
has exact synonym: treatment with anti-influenza drug
has exact synonym: treatment with anti-influenza medication

obsolete anxiolytics, other
type: Class
IAO_0100001: anxiolytic agent therapy
deprecated: true

antidepressant anxiolytics
type: Class
subclass of: anxiolytic agent therapy
IAO_0000115: Treatment with an antidepressant that can be used to treat anxiety.
date: 2019-01-22T20:32:25Z
creator: http://orcid.org/0000-0001-7941-2961

antimanic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35477
subclass of: mood and behavior-altering agent therapy
subclass of: psychotropic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35477
IAO_0000115: Treatment with used to treat bipolar disorders or mania associated with other affective disorders.
date: 2019-01-22T20:33:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35477
has exact synonym: antimanic agent drug treatment
has exact synonym: antimanic agent treatment therapy
has exact synonym: bipolar agent drug therapy
has exact synonym: bipolar agent drug treatment
has exact synonym: bipolar disorder agent therapy
has exact synonym: treatment with antimanic agent
has exact synonym: treatment with antimanic drug
has exact synonym: treatment with antimanic medication

antidiabetic agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with any agent that treats or prevents diabetes or diabetes symptoms.
date: 2019-01-22T20:33:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anti-diabetic therapy
has exact synonym: antidiabetic agent drug treatment
has exact synonym: antidiabetic therapy

glycemic agent therapy
type: Class
subclass of: blood glucose regulator therapy
IAO_0000115: Treatment with any drug or agent taken that maintains ando/or regulates blood glucose levels.
date: 2019-01-22T20:33:43Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: glycemic agent drug therapy
has exact synonym: glycemic regulation agent therapy
has exact synonym: glycemic regulation drug treatment
has exact synonym: glycemic regulator agent therapy

insulin treatment
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_145810
subclass of: hypoglycemic drug therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_145810
IAO_0000115: A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues.
date: 2019-01-22T20:33:51Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C581
has exact synonym: insulin drug treatment
has exact synonym: insulin therapy
has exact synonym: therapeutic insulin preparations treatment
has exact synonym: therapeutic insulin therapy

Axiom
annotated source: insulin treatment
annotated property: IAO_0000115
annotated target: A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues.
has db xref: NCIT:C581

central nervous system agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35470
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35470
IAO_0000115: Treatment with drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
date: 2019-01-22T20:34:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35470
has exact synonym: CNS agent therapy
has exact synonym: CNS drug therapy
has exact synonym: treatment with central nervous system drug

Axiom
annotated source: central nervous system agent therapy
annotated property: hasExactSynonym
annotated target: CNS agent therapy
has synonym type: OMO_0003000

Axiom
annotated source: central nervous system agent therapy
annotated property: hasExactSynonym
annotated target: CNS drug therapy
has synonym type: OMO_0003000

amphetamine agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_35338
subclass of: stimulant ADHD agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_35338
IAO_0000115: Treatment with a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine.
date: 2019-01-22T20:35:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35338
has db xref: NCIT:C62006
has exact synonym: amphetamine drug intake
has exact synonym: amphetamine drug therapy
has exact synonym: amphetamines therapy
has exact synonym: treatment with amphetamine agent
has exact synonym: treatment with amphetamine drug
has exact synonym: treatment with amphetamine medication
has exact synonym: treatment with amphetamines

non-stimulant ADHD agent therapy
type: Class
subclass of: ADHD agent therapy
IAO_0000115: Use of non-stimulant (non-amphetamine) medication for treatment of Attention Deficit Hyperactivity Disorder (ADHD).
date: 2019-01-22T20:35:24Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: non-amphetamine ADHD agent therapy
has narrow synonym: non-amphetamine ADHD drug therapy
has narrow synonym: non-stimulant ADHD treatment
has narrow synonym: non-stimulant Attention Deficient Hyperactivity Disorder agent therapy

Axiom
annotated source: non-stimulant ADHD agent therapy
annotated property: IAO_0000115
annotated target: Use of non-stimulant (non-amphetamine) medication for treatment of Attention Deficit Hyperactivity Disorder (ADHD).
has db xref: http://orcid.org/0000-0001-7941-2961

obsolete non-amphetamines, other
type: Class
IAO_0100001: non-stimulant ADHD agent therapy
deprecated: true

dental and oral agent therapy
type: Class
subclass of: pharmacotherapy
subclass of: MAXO_0001531
IAO_0000115: Any agent or drug used to treat oral diseases.
date: 2019-01-22T20:35:53Z
creator: http://orcid.org/0000-0001-7941-2961

dermatological agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50177
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50177
IAO_0000115: Use of a drug to treat or prevent skin disorders or for the routine care of skin.
date: 2019-01-22T20:36:09Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50177
has exact synonym: dermatologic agent therapy
has exact synonym: dermatologic drug treatment
has exact synonym: treatment with dermatolic drug
has exact synonym: treatment with dermatolic medication
has exact synonym: treatment with dermatolical drug
has exact synonym: treatment with dermatolical medication
has exact synonym: treatment with dermatologic drug

obsolete enzyme replacements and modifier agent therapy
type: Class
IAO_0100001: molecular pathway modifying agent therapy
deprecated: true

gastrointestinal agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_55324
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_55324
IAO_0000115: Use of a drug for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
date: 2019-01-22T20:36:38Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:55324
has exact synonym: gastrointestinal agent treatment
has exact synonym: gastrointestinal drug treatment
has exact synonym: gastrointestinal drug treatment therapy
has exact synonym: treatment with gastrointestinal drug
has exact synonym: treatment with gastrointestinal medication

gastrointestinal antispasmodics agent therapy
type: Class
subclass of: antispasticity agent therapy
subclass of: gastrointestinal agent therapy
IAO_0000115: Treatment to regulate muscle contractions in the gastrointestinal tract.
date: 2019-01-22T20:37:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: gastrointestinal anti-spasmodic agent therapy
has exact synonym: gastrointestinal antispasmodic agent therapy
has exact synonym: gastrointestinal antispasmodic drug treatment
has exact synonym: gastrointestinal antispasmodic treatment therapy

H2-receptor antagonist agent therapy
type: Class
subclass of: gastrointestinal agent therapy
IAO_0000115: H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
date: 2019-01-22T20:37:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:37961
has exact synonym: H2 blocker treatment therapy
has exact synonym: H2 blocking agent treatment therapy
has exact synonym: H2 receptor antagonist treatment therapy
has exact synonym: H2 receptor blockader treatment
has exact synonym: H2-receptor blocker therapy
has exact synonym: Histamine2 antagonist therapy
has exact synonym: histamine H2 receptor antagonist therapy
has exact synonym: histamine H2 receptor antagonist treatment
has exact synonym: histamine2 blocking agent therapy

Axiom
annotated source: H2-receptor antagonist agent therapy
annotated property: IAO_0000115
annotated target: H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
has db xref: CHEBI:37961

irritable bowel syndrome agent therapy
type: Class
subclass of: gastrointestinal agent therapy
IAO_0000115: Treatment with any agent that helps treat irritable bowel syndrome.
date: 2019-01-22T20:37:54Z
creator: http://orcid.org/0000-0001-7941-2961

gastrointestinal protectant agent therapy
type: Class
subclass of: gastrointestinal agent therapy
IAO_0000115: Treatment with medications that coat the ulcerated surfaces of gastrointestinal lining and are used mainly for peptic ulcer disease.
date: 2019-01-22T20:38:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: gastrointestinal protectant drug treatment
has exact synonym: gastrointestinal protectant treatment therapy
has exact synonym: gastroprotectant

proton pump inhibitor agent therapy
type: Class
subclass of: gastrointestinal agent therapy
IAO_0000115: Any one of the substituted benzimidazole compounds with anti-ulcer activity. A proton pump inhibitor is orally administered in the neutrally charged, inactive form and, upon entering the acidic environment of the parietal cell, gets protonated and converted into its active form. The active form will covalently and irreversibly bind to the proton pump, the H+/K+-ATPase, located on the surface of parietal cells. This leads to an inhibition of the transport of hydrogen ions, in exchange for potassium ions, into the gastric lumen and results in an inhibition of gastric acid secretion.
date: 2019-01-22T20:38:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C29723
has exact synonym: PPI agent therapy
has exact synonym: PPI drug therapy
has exact synonym: PPI treatment therapy
has exact synonym: proton pump inhibitor drug treatment
has exact synonym: proton pump inhibitor treatment therapy

Axiom
annotated source: proton pump inhibitor agent therapy
annotated property: IAO_0000115
annotated target: Any one of the substituted benzimidazole compounds with anti-ulcer activity. A proton pump inhibitor is orally administered in the neutrally charged, inactive form and, upon entering the acidic environment of the parietal cell, gets protonated and converted into its active form. The active form will covalently and irreversibly bind to the proton pump, the H+/K+-ATPase, located on the surface of parietal cells. This leads to an inhibition of the transport of hydrogen ions, in exchange for potassium ions, into the gastric lumen and results in an inhibition of gastric acid secretion.
has db xref: NCIT:C29723

Axiom
annotated source: proton pump inhibitor agent therapy
annotated property: hasExactSynonym
annotated target: PPI agent therapy
has synonym type: OMO_0003000

Axiom
annotated source: proton pump inhibitor agent therapy
annotated property: hasExactSynonym
annotated target: PPI drug therapy
has synonym type: OMO_0003000

Axiom
annotated source: proton pump inhibitor agent therapy
annotated property: hasExactSynonym
annotated target: PPI treatment therapy
has synonym type: OMO_0003000

obsolete gastrointestinal agents, other
type: Class
deprecated: true

genitourinary agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Use of a drug to treat conditions of the reproductive organs and excretory system or urinary tract.
date: 2019-01-22T20:39:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with genitourinary agent
has exact synonym: treatment with genitourinary drug
has exact synonym: treatment with genitourinary medication

urinary antispasmodic agent therapy
type: Class
subclass of: antispasticity agent therapy
subclass of: genitourinary agent therapy
IAO_0000115: Treatment to inhibit involuntary detrusor muscle contractions.
date: 2019-01-22T20:39:46Z
creator: http://orcid.org/0000-0001-7941-2961

benign prostate hypertrophy agent therapy
type: Class
subclass of: genitourinary agent therapy
IAO_0000115: Treatment with agent to increase urine flow in patients with an enlarged prostate.
date: 2019-01-22T20:40:09Z
creator: http://orcid.org/0000-0001-7941-2961

phosphate binders agent therapy
type: Class
subclass of: genitourinary agent therapy
IAO_0000115: Treatment with agents used to reduce the absorption of dietary phosphate
date: 2019-01-22T20:40:24Z
creator: http://orcid.org/0000-0001-7941-2961

obsolete genitourinary agents, other
type: Class
IAO_0100001: genitourinary agent therapy
deprecated: true

glucocorticoids/ mineralocorticoids therapy
type: Class
subclass of: adrenal-modifying, hormonal agent therapy
IAO_0000115: Treatments that are anti-inflammatory and immunosuppressive.
date: 2019-01-22T20:42:45Z
creator: http://orcid.org/0000-0001-7941-2961

pituitary-modifying, hormonal agent therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Treatment with an agent or medication that regulates hormones released by the pituitary.
date: 2019-01-22T20:44:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with pituitary modifier
has exact synonym: treatment with pituitary modifying agent
has exact synonym: treatment with pituitary modifying drug
has exact synonym: treatment with pituitary modifying medication

prostaglandin-modifying, hormonal agent therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Treatment with an agent regulating protaglandins.
date: 2019-01-22T20:45:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with prostaglandin modifier
has exact synonym: treatment with prostaglandin modifying agent
has exact synonym: treatment with prostaglandin modifying drug
has exact synonym: treatment with prostaglandin modifying medication

sex hormone modifying agent therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Treatment with any agent or medication that modifies androgen, estrogens, and/or progestogens.
date: 2019-01-22T20:46:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: sex hormone modifying drug treatment
has narrow synonym: gonadal steroid modifying agent therapy
has narrow synonym: gonadocorticoid modifying agent therapy

hormone modifying therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Use of any agent that can alter hormone levels or modulate hormone effects.
date: 2019-01-22T20:49:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C147908
has exact synonym: hormone modifiers
has exact synonym: hormone modifying agent
has exact synonym: hormone modifying drug
has exact synonym: hormone modifying drugs
has exact synonym: hormone therapies
has exact synonym: hormone therapy
has exact synonym: hormone therapy agents
has exact synonym: hormone therapy drugs
has exact synonym: treatment with hormone modifiers

thyroid-modifying hormonal agent therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Treatment with an agent or medication that regulates hormones released by the thyroid.
date: 2019-01-22T20:51:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with thyroid modifier
has exact synonym: treatment with thyroid modifying agent
has exact synonym: treatment with thyroid modifying drug
has exact synonym: treatment with thyroid modifying medication

anabolic steroid modifying agent therapy
type: Class
subclass of: sex hormone modifying agent therapy
IAO_0000115: Use of a compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power.
date: 2019-01-22T20:51:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:36413
has exact synonym: anabolic agent therapy
has exact synonym: anabolic steroid modifying drug treatment
has exact synonym: treatment with anabolic steroid

androgen modifying agent therapy
type: Class
subclass of: sex hormone modifying agent therapy
IAO_0000115: Treatment with an agent to modify androgen action.
date: 2019-01-22T20:51:44Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with androgen agent
has exact synonym: treatment with androgen drug
has exact synonym: treatment with androgen medication
has exact synonym: treatment with androgen modifying agent
has exact synonym: treatment with androgen modifying drug

estrogen modifying agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50739
subclass of: menopausal hormone therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50739
IAO_0000115: A drug which acts to modulates estrogenic activity in the body, either by modulating the amount of estrogen or by modulating the activity of whatever estrogen is present.
date: 2019-01-22T20:52:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50739
has exact synonym: estrogen modifying drug therapy
has exact synonym: estrogen modifying medication therapy
has exact synonym: oestrogen modifying agent therapy
has exact synonym: oestrogen modifying drug therapy
has exact synonym: treatment with estrogen receptor modulator
has exact synonym: treatment with estrogent modifying medication
has exact synonym: treatment with oestrogen modifying medication

progestin modifying agent therapy
type: Class
subclass of: menopausal hormone therapy
IAO_0000115: Treatment with an agent to modify progestin action.
date: 2019-01-22T20:52:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: progestin modifying drug treatment
has exact synonym: treatment with progestin modifier
has exact synonym: treatment with progestin modifying agent
has exact synonym: treatment with progestin modifying drug
has exact synonym: treatment with progestin modifying medication

selective-estrogen receptor modifying agent therapy
type: Class
subclass of: sex hormone modifying agent therapy
IAO_0000115: Treatment with an agent to that selectively modifies estrogen receptor action.
date: 2019-01-22T20:52:46Z
creator: http://orcid.org/0000-0001-7941-2961

parathyroid-suppressant hormone therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50827
subclass of: receptor antagonist therapy
subclass of: hormone modifying therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50827
IAO_0000115: Use of a drug to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones.
date: 2019-01-22T20:53:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50827
has exact synonym: antiparathyroid agent therapy
has exact synonym: treatment with antiparathyroid drug
has exact synonym: treatment with antiparathyroid medication
has exact synonym: treatment with parathyroid-suppressant agent
has exact synonym: treatment with parathyroid-suppressant drug
has exact synonym: treatment with parathyroid-suppressant medication

androgen stimulant agent therapy
type: Class
subclass of: androgen modifying agent therapy
IAO_0000115: Use of a compound which increases or activates the biosynthesis or actions of androgens.
date: 2019-01-22T20:54:46Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with androgen agonist
has exact synonym: treatment with androgen stimulant

androgen suppressant hormone agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35497
subclass of: receptor antagonist therapy
subclass of: androgen modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35497
IAO_0000115: Use of a compound which inhibits or antagonizes the biosynthesis or actions of androgens.
date: 2019-01-22T20:55:10Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35497
has exact synonym: treatment with androgen antagonist
has exact synonym: treatment with androgen blocker
has exact synonym: treatment with androgen suppressant agent

thyroid-stimulating hormonal agent therapy
type: Class
subclass of: thyroid-modifying hormonal agent therapy
IAO_0000115: Treatment with an agent or medication that stimulates hormones released by the thyroid.
date: 2019-01-22T20:59:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with thyroid agonist
has exact synonym: treatment with thyroid stimulating agent
has exact synonym: treatment with thyroid stimulating drug
has exact synonym: treatment with thyroid stimulating medication
has exact synonym: treatment with thyroid-stimulating agent

antithyroid agent therapy
type: Class
subclass of: thyroid-modifying hormonal agent therapy
IAO_0000115: Use of a drug to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
date: 2019-01-22T20:59:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50671
has exact synonym: anti-thyroid drug treatment
has exact synonym: treatment with anti-thyroid agent
has exact synonym: treatment with antithyroid agent
has exact synonym: treatment with antithyroid drug
has exact synonym: treatment with antithyroid medication

immunological agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50846
subclass of: pharmacotherapy
subclass of: immunotherapy procedure
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50846
IAO_0000115: Use of a drug that induces, enhances, restores or suppresses the host's immune system, or an agent that utilizes or is derived from a component of the immune system.
date: 2019-01-22T21:00:01Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50846
has db xref: NCIT:C308
has exact synonym: immune factor therapy
has exact synonym: immune mediator treatment therapy
has exact synonym: immune modulator therapy
has exact synonym: immune regulator therapy
has exact synonym: immunological agent treatment therapy
has exact synonym: immunomodulating agent treatment therapy
has exact synonym: immunomodulator treatment therapy
has exact synonym: immunomodulatory agent treatment therapy
has exact synonym: immunotherapeutic agent treatment therapy
has exact synonym: immunotherapy agent
has exact synonym: immunotherapy treatment
has exact synonym: treatment with immunological agent
has exact synonym: treatment with immunological drug
has exact synonym: treatment with immunological medication
has exact synonym: treatment with immunomodifying agent
has exact synonym: treatment with immunomodifying drug
has exact synonym: treatment with immunomodifying medication
has exact synonym: treatment with immunomodulator

immune stimulant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50847
subclass of: immunological agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50847
IAO_0000115: Use of a substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level.
date: 2019-01-22T21:00:13Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50847
has exact synonym: immunoactivator treatment therapy
has exact synonym: immunoadjuvant treatment therapy
has exact synonym: immunologic adjuvant treatment therapy
has exact synonym: immunological adjuvant treatment therapy
has exact synonym: immunopotentiator treatment therapy
has exact synonym: immunostimulant treatment therapy
has exact synonym: treatment with immune stimulant
has exact synonym: treatment with immunoactivator
has exact synonym: treatment with immunoadjuvant
has exact synonym: treatment with immunological adjuvant
comment: A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.

Axiom
annotated source: immune stimulant agent therapy
annotated property: comment
annotated target: A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
has db xref: CHEBI:50847

immune suppressant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35705
subclass of: immunological agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35705
IAO_0000115: Use of an agent that suppresses immune function by one of several mechanisms of action.
date: 2019-01-22T21:00:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35705
has db xref: NCIT:C574
has exact synonym: immune suppressant agent treatment
has exact synonym: immunosuppressant agent therapy
has exact synonym: immunosuppressant treatment therapy
has exact synonym: immunosuppressive agent treatment therapy
has exact synonym: immunosuppressor agent therapy
has exact synonym: treatment immunosuppressant
has exact synonym: treatment with immune suppressant
has exact synonym: treatment with immunosuppressive
has exact synonym: treatment with immunosuppressive agent
comment: Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.

Axiom
annotated source: immune suppressant agent therapy
annotated property: comment
annotated target: Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
has db xref: CHEBI:35705

passive immunizing agent therapy
type: Class
subclass of: immunological agent therapy
IAO_0000115: Treatment with antibodies to a disease to provide a temporary immunity.
date: 2019-01-22T21:00:40Z
creator: http://orcid.org/0000-0001-7941-2961

inflammatory bowel disease agent therapy
type: Class
subclass of: gastrointestinal agent therapy
IAO_0000115: The drug treatment of inflammatory bowel disease (IBD), which may include the use of anti-inflammatory agents and agents that reduce the symptoms associated with IBD.
date: 2019-01-22T21:01:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: PMID:21857074
has exact synonym: anti-IBD drug treatment therapy
has exact synonym: anti-inflammatory bowel disease drug treatment
has exact synonym: anti-inflammatory bowel disease therapy

Axiom
annotated source: inflammatory bowel disease agent therapy
annotated property: IAO_0000115
annotated target: The drug treatment of inflammatory bowel disease (IBD), which may include the use of anti-inflammatory agents and agents that reduce the symptoms associated with IBD.
has db xref: PMID:21857074

salicylate agent therapy
type: Class
subclass of: inflammatory bowel disease agent therapy
IAO_0000115: The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
date: 2019-01-22T21:02:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: DBCAT000579
has db xref: CHEBI:30762

Axiom
annotated source: salicylate agent therapy
annotated property: IAO_0000115
annotated target: The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
has db xref: DBCAT000579

metabolic bone disease agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with drug or agent to treat or prevent deformities or abnormalities of the bone caused by a metabolic disorder.
date: 2019-01-22T21:04:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: metabolic bone disease drug treatment

ophthalmic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_66981
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_66981
IAO_0000115: Use of a drug to treat eye conditions or eye diseases.
date: 2019-01-22T21:04:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:66981
has exact synonym: ophthalmic drug treatment
has exact synonym: ophthalmics drug treatment
has exact synonym: ophthalmologicals therapy
has exact synonym: ophthalmology agent therapy
has exact synonym: ophthalmology agent treatment therapy
has exact synonym: treatment with ophthalmic agent
has exact synonym: treatment with ophthalmic drug
has exact synonym: treatment with ophthalmic medication
has exact synonym: treatment with ophthalmology drug

ophthalmic anti-allergy agent therapy
type: Class
subclass of: ophthalmic agent therapy
subclass of: allergy agent therapy
IAO_0000115: Treatment with medication delivered directly to the eye to treat allergies or allergy symptoms.
date: 2019-01-22T21:04:55Z
creator: http://orcid.org/0000-0001-7941-2961

antiglaucoma agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_39456
subclass of: ophthalmic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_39456
IAO_0000115: Use of a drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision.
date: 2019-01-22T21:05:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:39456
has exact synonym: ophthalmic antiglaucoma agent therapy
has exact synonym: treatment with anti-glaucoma agent
has exact synonym: treatment with anti-glaucoma medication
has exact synonym: treatment with antiglaucoma agent
has exact synonym: treatment with antiglaucoma drug
has exact synonym: treatment with antiglaucoma medication

ophthalmic anti-inflammatory agent therapy
type: Class
subclass of: anti-inflammatory agent therapy
subclass of: ophthalmic agent therapy
IAO_0000115: Treatment with an agent or medication formulated to be applied in the eyes, to reduce pain or to treat inflammation, especially used after eye surgery to relieve pain.
date: 2019-01-22T21:05:47Z
creator: http://orcid.org/0000-0001-7941-2961

ophthalmic prostaglandin and prostamide agent therapy
type: Class
subclass of: ophthalmic agent therapy
IAO_0000115: Treatment with an agent applied directly to the eye to treat elevated intraocular pressure (IOP) via regulating prostaglandin and prostamide.
date: 2019-01-22T21:06:19Z
creator: http://orcid.org/0000-0001-7941-2961

obsolete ophthalmic agents, other
type: Class
IAO_0100001: ophthalmic agent therapy
deprecated: true

otic agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with a substance intended for administration either on the outer ear or into the auditory canal.
date: 2019-01-22T21:08:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C69040
has exact synonym: NCIT:C69040
has exact synonym: treatment with otic medication

respiratory tract agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: An agent that exerts a physiologic effect on any anatomic entity that is part of the respiratory tract and airways.
date: 2019-01-22T21:08:56Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C78273
has exact synonym: agent affecting respiratory system treatment
has exact synonym: respiratory tract agent treatment
has exact synonym: respiratory tract drug treatment therapy
has exact synonym: treatment with respiratory tract agent
has exact synonym: treatment with respiratory tract medication

Axiom
annotated source: respiratory tract agent therapy
annotated property: IAO_0000115
annotated target: An agent that exerts a physiologic effect on any anatomic entity that is part of the respiratory tract and airways.
has db xref: NCIT:C78273

antihistamine agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37956
subclass of: receptor antagonist therapy
subclass of: anticholinergic bronchodilator agent therapy
subclass of: allergy agent therapy
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_37956
IAO_0000115: Use of drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
date: 2019-01-22T21:09:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:37956
has exact synonym: antihistamine drug treatment
has exact synonym: antihistimine drug therapy
has exact synonym: histamine receptor blocker drug treatment
has exact synonym: histamine receptor blocker therapy
has exact synonym: treatment with antihistamine
has exact synonym: treatment with histamine antagonist
has exact synonym: treatment with histamine blocker

inhaled corticosteroid agent therapy
type: Class
subclass of: respiratory tract agent therapy
IAO_0000115: Treatment with an inhaled agent that reduces inflammation and mucus in the airways that carry air to the lungs.
date: 2019-01-22T21:09:38Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: inhaled corticosteroid drug treatment

antileukotriene agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_49159
subclass of: receptor antagonist therapy
subclass of: respiratory tract agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_49159
IAO_0000115: Use of a drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
date: 2019-01-22T21:09:53Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:49159
has exact synonym: antileukotriene drug treatment
has exact synonym: treatment with antileukotriene agent
has exact synonym: treatment with antileukotriene medication
has exact synonym: treatment with leukotriene antagonist
has exact synonym: treatment with leukotriene blocker

bronchodilator therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35523
subclass of: respiratory tract agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35523
IAO_0000115: Use of an agent that causes an increase in the expansion of a bronchus or bronchial tubes.
date: 2019-01-22T21:10:11Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35523
has db xref: NCIT:C319
has exact synonym: bronchodilator agent treatment
has exact synonym: bronchodilator drug treatment
has exact synonym: broncholytic agent therapy
has exact synonym: treatment with bronchodilator
has exact synonym: treatment with bronchodilator agent

anticholinergic bronchodilator agent therapy
type: Class
subclass of: bronchodilator therapy
IAO_0000115: Treatment with an agent that blocks the effect of acetylcholine in airways and nasal passages to keep the airways from constricting during asthma and allergy-related brathing issues.
date: 2019-01-22T21:10:37Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anticholinergic bronchodilator drug treatment

phosphodiesterase inhibitor bronchodilator agent therapy
type: Class
subclass of: bronchodilator therapy
subclass of: phosphodiesterase inhibitor therapy
IAO_0000115: Treatment with a phosphodiesterase (PDE) inhibitor that decreases mean pulmonary arterial pressure.
date: 2019-01-22T21:11:08Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: phosphodiesterase inhibitor bronchodilator drug treatment

sympathomimetic bronchodilator agent therapy
type: Class
subclass of: bronchodilator therapy
IAO_0000115: Treatment with an agent for reversible airway obstruction in diseases such as asthma and COPD. These agents produce bronchodilation by stimulating beta2 adrenergic receptors on airway smooth muscle.
date: 2019-01-22T21:11:37Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: adrenergic bronchiodilator agent therapy
has exact synonym: adrenergic bronchiodilator agent treatment
has exact synonym: adrenergic bronchiodilator drug therapy
has exact synonym: sympathomimetic bronchodilator drug therapy
has exact synonym: treatment with adrenergic bronchiodilator agent

mast cell stabilizer agent therapy
type: Class
subclass of: respiratory tract agent therapy
IAO_0000115: Treatment with an agent that block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and other factors thereby preventing or regulating allergic disorders.
date: 2019-01-22T21:12:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C29714
has exact synonym: mast cell stabiliser agent therapy
has exact synonym: mast cell stabiliser drug treatment
has exact synonym: mast cell stabilizer drug treatment

pulmonary antihypertensive agent therapy
type: Class
subclass of: respiratory tract agent therapy
IAO_0000115: Treatment with an agent that decreases pulmonary hypertension.
date: 2019-01-22T21:12:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: pulmonary antihypertensive drug treatment

obsolete respiratory tract agents, other
type: Class
IAO_0100001: respiratory tract agent therapy
deprecated: true

sedatives and hypnotic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35717
subclass of: psychotropic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35717
IAO_0000115: Treatment with a central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
date: 2019-01-22T21:14:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35717
has db xref: NCIT:C29756
has exact synonym: hypnotic agent therapy
has exact synonym: hypnotic drug therapy
has exact synonym: hypnotics agent therapy
has exact synonym: sedative agent drug therapy
has exact synonym: sedative agent drug treatment
has exact synonym: sedative and hypnotic drug treatment
has exact synonym: sedative drug therapy
has exact synonym: sedative drug treatment
has exact synonym: sedative treatment therapy
has exact synonym: sedative-hypnotic drug treatment
has exact synonym: sedatives and hypnotic drug therapy
has exact synonym: sedatives/hypnotic drug treatment
has exact synonym: treatment with sedative

Axiom
annotated source: sedatives and hypnotic agent therapy
annotated property: IAO_0000115
annotated target: Treatment with a central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
has db xref: CHEBI:35717

skeletal muscle relaxant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_51371
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_51371
IAO_0000115: Use of a drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
date: 2019-01-22T21:14:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:51371
has db xref: NCIT:C29696
has exact synonym: muscle relaxant agent therapy
has exact synonym: skeletal muscle relaxant drug treatment
has exact synonym: treatment with muscle relaxant

anti-infective agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35441
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35441
IAO_0000115: Use of a substance for the prophylaxis or therapy of infectious diseases.
date: 2019-04-10T19:56:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35441
has exact synonym: anti-infective drug therapy
has exact synonym: treatment with anti-infective agent
has exact synonym: treatment with anti-infective drug
has exact synonym: treatment with anti-infective medication
has exact synonym: treatment with antiinfective agent
has exact synonym: treatment with antiinfective drug
has exact synonym: treatment with antiinfective medication

biopsy of head
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000033
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000033
IAO_0000115: Removal and examination of tissue, cells, or fluids from head for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: head biopsy

biopsy of abdomen
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000916
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000916
IAO_0000115: Removal and examination of tissue, cells, or fluids from abdomen for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: abdomen biopsy

biopsy of adipose tissue
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001013
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001013
IAO_0000115: Removal and examination of tissue, cells, or fluids from adipose for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: adipose tissue biopsy

biopsy of adrenal cortex
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001235
subclass of: biopsy of adrenal gland
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001235
IAO_0000115: Removal and examination of tissue, cells, or fluids from adrenal cortex for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: adrenal cortex biopsy

biopsy of adrenal gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002369
subclass of: biopsy of abdomen
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002369
IAO_0000115: Removal and examination of tissue, cells, or fluids from adrenal gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: adrenal gland biopsy

biopsy of anal canal
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000159
subclass of: biopsy of large intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000159
IAO_0000115: Removal and examination of tissue, cells, or fluids from anal canal for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: anal canal biopsy

anal biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001245
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001245
IAO_0000115: Removal and examination of tissue, cells, or fluids from anus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has db xref: NCIT:C51586
has exact synonym: anus biopsy

biopsy of aorta
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000947
subclass of: diagnostic procedure of cardiovascular system
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000947
IAO_0000115: Removal and examination of tissue, cells, or fluids from aorta for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: aorta biopsy

uterine biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0009853
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0009853
IAO_0000115: Removal and examination of tissue, cells, or fluids from the uterus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: biopsy of uterus
has exact synonym: body of uterus biopsy

calcified bone biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001474
subclass of: clinical biopsy by site
subclass of: MAXO_0001405
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001474
IAO_0000115: Removal and examination of tissue, cells, or fluids from the calcified bone for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: biopsy of the bone
has exact synonym: bone element biopsy

biopsy of bone marrow
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002371
subclass of: calcified bone biopsy
subclass of: MAXO_0001402
subclass of: MAXO_0001446
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002371
IAO_0000115: Removal and examination of tissue, cells, or fluids from bone marrow for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: bone marrow biopsy

biopsy of bone tissue
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002481
subclass of: calcified bone biopsy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002481
IAO_0000115: Removal and examination of tissue, cells, or fluids from bone tissue for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: bone tissue biopsy

biopsy of brain
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000955
subclass of: clinical biopsy by site
subclass of: MAXO_0001406
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000955
IAO_0000115: Removal and examination of tissue, cells, or fluids from brain for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: brain biopsy

biopsy of brainstem
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002298
subclass of: biopsy of brain
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002298
IAO_0000115: Removal and examination of tissue, cells, or fluids from brainstem for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: brainstem biopsy

biopsy of breast
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000310
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000310
IAO_0000115: Removal and examination of tissue, cells, or fluids from breast for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: breast biopsy

bronchial biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002185
subclass of: biopsy of lower respiratory tract
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002185
IAO_0000115: Removal and examination of tissue, cells, or fluids from bronchus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: bronchus biopsy

biopsy of caecum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001153
subclass of: biopsy of colon
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001153
IAO_0000115: Removal and examination of tissue, cells, or fluids from caecum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: caecum biopsy

biopsy of cardiac ventricle
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002082
subclass of: biopsy of heart
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002082
IAO_0000115: Removal and examination of tissue, cells, or fluids from cardiac ventricle for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: cardiac ventricle biopsy

biopsy of cerebellum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002037
subclass of: biopsy of brain
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002037
IAO_0000115: Removal and examination of tissue, cells, or fluids from cerebellum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: cerebellum biopsy

biopsy of cerebral cortex
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000956
subclass of: biopsy of brain
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000956
IAO_0000115: Removal and examination of tissue, cells, or fluids from cerebral cortex for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: cerebral cortex biopsy

biopsy of chest wall
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0016435
subclass of: clinical biopsy by site
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0016435
IAO_0000115: Removal and examination of tissue, cells, or fluids from chest wall for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: chest wall biopsy

biopsy of chordate pharynx
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001042
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001042
IAO_0000115: Removal and examination of tissue, cells, or fluids from chordate pharynx for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: chordate pharynx biopsy

biopsy of choroid plexus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001886
subclass of: biopsy of brain
subclass of: diagnostic procedure of cardiovascular system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001886
IAO_0000115: Removal and examination of tissue, cells, or fluids from choroid plexus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: choroid plexus biopsy

biopsy of cochlea
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001844
subclass of: biopsy of head
subclass of: calcified bone biopsy
subclass of: MAXO_0001445
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001844
IAO_0000115: Removal and examination of tissue, cells, or fluids from cochlea for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: cochlea biopsy

biopsy of colon
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001155
subclass of: biopsy of large intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001155
IAO_0000115: Removal and examination of tissue, cells, or fluids from colon for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: colon biopsy

biopsy of colorectum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0012652
subclass of: biopsy of large intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0012652
IAO_0000115: Removal and examination of tissue, cells, or fluids from colorectum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: colorectum biopsy

biopsy of dermis
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002067
subclass of: clinical biopsy by site
subclass of: MAXO_0001404
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002067
IAO_0000115: Removal and examination of tissue, cells, or fluids from dermis for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: dermis biopsy

biopsy of diaphragm
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001103
subclass of: clinical biopsy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001103
IAO_0000115: Removal and examination of tissue, cells, or fluids from diaphragm for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: diaphragm biopsy

biopsy of thalamus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001897
subclass of: biopsy of brain
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001897
IAO_0000115: Removal and examination of tissue, cells, or fluids from the thalamus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: dorsal plus ventral thalamus biopsy

biopsy of duodenum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002114
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002114
IAO_0000115: Removal and examination of tissue, cells, or fluids from duodenum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: duodenum biopsy

biopsy of endocardium
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002165
subclass of: biopsy of heart
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002165
IAO_0000115: Removal and examination of tissue, cells, or fluids from endocardium for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: endocardium biopsy

biopsy of endocrine pancreas
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000016
subclass of: biopsy of pancreas
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000016
IAO_0000115: Removal and examination of tissue, cells, or fluids from endocrine pancreas for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: endocrine pancreas biopsy

biopsy of endometrium
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001295
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001295
IAO_0000115: Removal and examination of tissue, cells, or fluids from endometrium for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: endometrium biopsy

biopsy of esophagus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001043
subclass of: biopsy of upper digestive tract
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001043
IAO_0000115: Removal and examination of tissue, cells, or fluids from esophagus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: esophagus biopsy

biopsy of eye
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000970
subclass of: ophthalmic diagnostic procedure
subclass of: clinical biopsy by site
IAO_0000115: Removal and examination of tissue, cells, or fluids from eye for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: eye biopsy

biopsy of fallopian tube
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003889
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003889
IAO_0000115: Removal and examination of tissue, cells, or fluids from fallopian tube for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: fallopian tube biopsy

biopsy of frontal lobe
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0016525
subclass of: clinical biopsy by site
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0016525
IAO_0000115: Removal and examination of tissue, cells, or fluids from frontal lobe for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: frontal lobe biopsy

biopsy of gallbladder
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002110
subclass of: biopsy of abdomen
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002110
IAO_0000115: Removal and examination of tissue, cells, or fluids from gallbladder for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: gallbladder biopsy

biopsy of genitourinary system
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004122
subclass of: clinical biopsy by site
subclass of: MAXO_0001401
IAO_0000115: Removal and examination of tissue, cells, or fluids from genitourinary system for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: genitourinary system biopsy

biopsy of gonad
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000991
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000991
IAO_0000115: Removal and examination of tissue, cells, or fluids from gonad for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: gonad biopsy

biopsy of heart
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000948
subclass of: diagnostic procedure of cardiovascular system
subclass of: clinical biopsy by site
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000948
IAO_0000115: Removal and examination of tissue, cells, or fluids from heart for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: heart biopsy

biopsy of hypopharynx
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001051
subclass of: biopsy of chordate pharynx
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001051
IAO_0000115: Removal and examination of tissue, cells, or fluids from hypopharynx for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: hypopharynx biopsy

biopsy of hypothalamus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001898
subclass of: biopsy of brain
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001898
IAO_0000115: Removal and examination of tissue, cells, or fluids from hypothalamus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: hypothalamus biopsy

biopsy of intestine
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000160
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000160
IAO_0000115: Removal and examination of tissue, cells, or fluids from intestine for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: intestine biopsy

biopsy of jaw bone
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001708
subclass of: biopsy of head
subclass of: biopsy of mouth
subclass of: MAXO_0001405
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001708
IAO_0000115: Removal and examination of tissue, cells, or fluids from the jaw bone for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: jaw skeleton biopsy

biopsy of lacrimal apparatus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001750
subclass of: biopsy of head
subclass of: biopsy of eye
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001750
IAO_0000115: Removal and examination of tissue, cells, or fluids from lacrimal apparatus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lacrimal apparatus biopsy

biopsy of large intestine
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000059
subclass of: biopsy of intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000059
IAO_0000115: Removal and examination of tissue, cells, or fluids from large intestine for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: large intestine biopsy

biopsy of larynx
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001737
subclass of: clinical biopsy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001737
IAO_0000115: Removal and examination of tissue, cells, or fluids from larynx for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: larynx biopsy

biopsy of limb
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002101
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002101
IAO_0000115: Removal and examination of tissue, cells, or fluids from limb for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: limb biopsy

biopsy of lip
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001833
subclass of: biopsy of head
subclass of: biopsy of mouth
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001833
IAO_0000115: Removal and examination of tissue, cells, or fluids from lip for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lip biopsy

biopsy of liver
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002107
subclass of: biopsy of abdomen
subclass of: MAXO_0001396
subclass of: MAXO_0001400
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
IAO_0000115: Removal and examination of tissue, cells, or fluids from liver for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: liver biopsy

biopsy of lower respiratory tract
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001558
subclass of: clinical biopsy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001558
IAO_0000115: Removal and examination of tissue, cells, or fluids from lower respiratory tract for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lower respiratory tract biopsy

biopsy of lower urinary tract
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001556
subclass of: clinical biopsy by site
subclass of: MAXO_0001399
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001556
IAO_0000115: Removal and examination of tissue, cells, or fluids from lower urinary tract for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lower urinary tract biopsy

biopsy of lumbar spine
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0006074
subclass of: clinical biopsy by site
subclass of: MAXO_0001405
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0006074
IAO_0000115: Removal and examination of tissue, cells, or fluids from the lumbar spine for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lumbar region of vertebral column biopsy
has exact synonym: lumbar spine biopsy

biopsy of lung
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002048
subclass of: clinical biopsy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002048
IAO_0000115: Removal and examination of tissue, cells, or fluids from lung for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lung biopsy

biopsy of lymph node
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000029
subclass of: clinical biopsy by site
subclass of: MAXO_0001446
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000029
IAO_0000115: Removal and examination of tissue, cells, or fluids from lymph node for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lymph node biopsy

biopsy of lymphatic system
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0006558
subclass of: clinical biopsy by site
subclass of: MAXO_0001398
subclass of: MAXO_0001446
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0006558
IAO_0000115: Removal and examination of tissue, cells, or fluids from the lymphatic system for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: lymphatic part of lymphoid system biopsy

biopsy of vulva
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000997
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000997
IAO_0000115: Removal and examination of tissue, cells, or fluids from the vulva for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: mammalian vulva biopsy
has exact synonym: vulva biopsy
has exact synonym: vulval biopsy

biopsy of medulla oblongata
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001896
subclass of: biopsy of brainstem
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001896
IAO_0000115: Removal and examination of tissue, cells, or fluids from medulla oblongata for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: medulla oblongata biopsy

biopsy of mouth
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000165
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000165
IAO_0000115: Removal and examination of tissue, cells, or fluids from mouth for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: biopsy of oral cavity
has exact synonym: mouth biopsy

obsolete biopsy of muscle
type: Class
IAO_0100001: biopsy of muscle tissue
deprecated: true

biopsy of muscle tissue
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002385
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002385
IAO_0000115: Removal and examination of tissue, cells, or fluids from muscle tissue for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: muscle biopsy
has exact synonym: muscle tissue biopsy

biopsy of nasolacrimal duct
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002392
subclass of: biopsy of lacrimal apparatus
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002392
IAO_0000115: Removal and examination of tissue, cells, or fluids from nasolacrimal duct for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: nasolacrimal duct biopsy

biopsy of nasopharynx
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001728
subclass of: biopsy of chordate pharynx
subclass of: biopsy of upper respiratory tract
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001728
IAO_0000115: Removal and examination of tissue, cells, or fluids from nasopharynx for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: nasopharynx biopsy

biopsy of neck
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000974
subclass of: clinical biopsy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000974
IAO_0000115: Removal and examination of tissue, cells, or fluids from neck for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: neck biopsy

biopsy of ovary
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000992
subclass of: biopsy of gonad
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000992
IAO_0000115: Removal and examination of tissue, cells, or fluids from ovary for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: ovary biopsy

biopsy of pancreas
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001264
subclass of: clinical biopsy by site
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
IAO_0000115: Removal and examination of tissue, cells, or fluids from pancreas for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: pancreas biopsy

biopsy of penis
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000989
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000989
IAO_0000115: Removal and examination of tissue, cells, or fluids from penis for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: penis biopsy

biopsy of perianal skin
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0012336
subclass of: biopsy of skin
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0012336
IAO_0000115: Removal and examination of tissue, cells, or fluids from perianal skin for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: perianal skin biopsy

biopsy of peritoneum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002358
subclass of: biopsy of abdomen
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002358
IAO_0000115: Removal and examination of tissue, cells, or fluids from peritoneum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: peritoneum biopsy

biopsy of pituitary gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000007
subclass of: biopsy of brain
subclass of: MAXO_0001407
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000007
IAO_0000115: Removal and examination of tissue, cells, or fluids from pituitary gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: pituitary gland biopsy

biopsy of pleura
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000977
subclass of: biopsy of lower respiratory tract
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000977
IAO_0000115: Removal and examination of tissue, cells, or fluids from pleura for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: pleura biopsy

biopsy of rectum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001052
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001052
IAO_0000115: Removal and examination of tissue, cells, or fluids from rectum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: rectum biopsy

biopsy of retina
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000966
subclass of: biopsy of head
subclass of: biopsy of eye
subclass of: MAXO_0001406
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000966
IAO_0000115: Removal and examination of tissue, cells, or fluids from retina for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: retina biopsy

biopsy of salivary gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001044
subclass of: biopsy of mouth
subclass of: MAXO_0001400
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001044
IAO_0000115: Removal and examination of tissue, cells, or fluids from the salivary gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: saliva-secreting gland biopsy
has exact synonym: salivary gland biopsy

biopsy of scrotum
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001300
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001300
IAO_0000115: Removal and examination of tissue, cells, or fluids from scrotum for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: scrotum biopsy

biopsy of sebaceous gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001821
subclass of: clinical biopsy by site
subclass of: MAXO_0001400
subclass of: MAXO_0001404
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001821
IAO_0000115: Removal and examination of tissue, cells, or fluids from sebaceous gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: sebaceous gland biopsy

biopsy of small intestine
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002108
subclass of: biopsy of intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002108
IAO_0000115: Removal and examination of tissue, cells, or fluids from small intestine for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: small intestine biopsy

biopsy of spinal cord
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002240
subclass of: clinical biopsy by site
subclass of: MAXO_0001406
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002240
IAO_0000115: Removal and examination of tissue, cells, or fluids from spinal cord for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: spinal cord biopsy

biopsy of spleen
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002106
subclass of: biopsy of abdomen
subclass of: MAXO_0001402
subclass of: MAXO_0001446
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002106
IAO_0000115: Removal and examination of tissue, cells, or fluids from spleen for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: spleen biopsy

biopsy of stomach
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000945
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000945
IAO_0000115: Removal and examination of tissue, cells, or fluids from stomach for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: stomach biopsy

biopsy of subglottis
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0036068
subclass of: biopsy of larynx
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0036068
IAO_0000115: Removal and examination of tissue, cells, or fluids from subglottis for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: subglottis biopsy

biopsy of submandibular gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001736
subclass of: biopsy of salivary gland
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001736
IAO_0000115: Removal and examination of tissue, cells, or fluids from submandibular gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: submandibular gland biopsy

biopsy of testis
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000473
subclass of: biopsy of gonad
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000473
IAO_0000115: Removal and examination of tissue, cells, or fluids from testis for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: testis biopsy

biopsy of thymus
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002370
subclass of: clinical biopsy by site
subclass of: MAXO_0001402
subclass of: MAXO_0001446
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
IAO_0000115: Removal and examination of tissue, cells, or fluids from thymus for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: thymus biopsy

biopsy of thyroid gland
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002046
subclass of: clinical biopsy by site
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002046
IAO_0000115: Removal and examination of tissue, cells, or fluids from thyroid gland for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: thyroid gland biopsy

biopsy of tongue
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001723
subclass of: biopsy of mouth
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001723
IAO_0000115: Removal and examination of tissue, cells, or fluids from tongue for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: tongue biopsy

biopsy of tonsil
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002372
subclass of: biopsy of chordate pharynx
subclass of: MAXO_0001446
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002372
IAO_0000115: Removal and examination of tissue, cells, or fluids from tonsil for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: tonsil biopsy

biopsy of trachea
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003126
subclass of: biopsy of lower respiratory tract
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003126
IAO_0000115: Removal and examination of tissue, cells, or fluids from trachea for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: trachea biopsy

biopsy of upper digestive tract
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004908
subclass of: clinical biopsy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004908
IAO_0000115: Removal and examination of tissue, cells, or fluids from upper digestive tract for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: upper digestive tract biopsy

biopsy of upper respiratory tract
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001557
subclass of: clinical biopsy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001557
IAO_0000115: Removal and examination of tissue, cells, or fluids from upper respiratory tract for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: upper respiratory tract biopsy

biopsy of ureter
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000056
subclass of: clinical biopsy by site
subclass of: MAXO_0001399
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000056
IAO_0000115: Removal and examination of tissue, cells, or fluids from ureter for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: ureter biopsy

biopsy of urethra
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000057
subclass of: biopsy of lower urinary tract
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000057
IAO_0000115: Removal and examination of tissue, cells, or fluids from urethra for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: urethra biopsy

biopsy of bladder
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001255
subclass of: biopsy of lower urinary tract
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001255
IAO_0000115: Removal and examination of tissue, cells, or fluids from the bladder for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: urinary bladder biopsy

biopsy of cervix
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000002
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000002
IAO_0000115: Removal and examination of tissue, cells, or fluids from uterine cervix for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: uterine cervix biopsy

biopsy of vagina
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000996
subclass of: clinical biopsy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000996
IAO_0000115: Removal and examination of tissue, cells, or fluids from vagina for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: vagina biopsy

biopsy of appendix
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001154
subclass of: biopsy of large intestine
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001154
IAO_0000115: Removal and examination of tissue, cells, or fluids from the appendix for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: vermiform appendix biopsy

biopsy of skin
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000014
subclass of: clinical biopsy by site
subclass of: MAXO_0001404
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000014
IAO_0000115: Removal and examination of tissue, cells, or fluids from the skin for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: skin biopsy
has exact synonym: zone of skin biopsy

magnetic resonance imaging procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide amazingly clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.
date: 2019-04-26T17:25:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16809
has exact synonym: MRI scan for therapeutics
has exact synonym: NMRI
has exact synonym: clinical magnetic resonance imaging procedure
has exact synonym: medical magnetic resonance imaging procedure
has exact synonym: nuclear magnetic resonance imaging for medical therapy
has exact synonym: therapeutic MRI

Axiom
annotated source: magnetic resonance imaging procedure
annotated property: IAO_0000115
annotated target: Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide amazingly clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.
has db xref: NCIT:C16809

Axiom
annotated source: magnetic resonance imaging procedure
annotated property: hasExactSynonym
annotated target: MRI scan for therapeutics
has synonym type: hasSynonymType

Axiom
annotated source: magnetic resonance imaging procedure
annotated property: hasExactSynonym
annotated target: NMRI
has synonym type: OMO_0003000

Axiom
annotated source: magnetic resonance imaging procedure
annotated property: hasExactSynonym
annotated target: therapeutic MRI
has synonym type: OMO_0003000

MRI of the head
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000033
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000033
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the head.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the head
has exact synonym: head MRI
has exact synonym: head magnetic resonance imaging

MRI of the abdomen
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000916
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000916
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the abdomen.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the abdomen
has exact synonym: abdomen MRI
has exact synonym: abdomen magnetic resonance imaging
has exact synonym: abdominal MRI

MRI of the brain
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000955
subclass of: MRI of the head
subclass of: MAXO_0001406
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000955
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the brain.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the brain
has exact synonym: brain MRI
has exact synonym: brain magnetic resonance imaging

MRI of the chest
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001443
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001443
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the chest.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the chest
has exact synonym: chest MRI
has exact synonym: chest magnetic resonance imaging

external beam radiation therapy
type: Class
subclass of: radiation therapy
IAO_0000115: Radiation therapy in which high-energy beams are delivered to a body part and/or tumor from outside of the body.
date: 2019-04-26T19:28:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: EBRT
has exact synonym: external beam RT
has exact synonym: external beam radiotherapeutics
has exact synonym: external beam radiotherapy
has exact synonym: external-beam radiation
has narrow synonym: External radiation therapy

Axiom
annotated source: external beam radiation therapy
annotated property: hasExactSynonym
annotated target: EBRT
has synonym type: OMO_0003000

Axiom
annotated source: external beam radiation therapy
annotated property: hasExactSynonym
annotated target: external beam RT
has synonym type: OMO_0003000

internal radiation therapy
type: Class
subclass of: radiation therapy
IAO_0000115: A type of radiation therapy in which radioactive material is placed inside the body, into a tumor or body cavity.
date: 2019-04-26T19:28:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15195
has exact synonym: Brachytherapy
has exact synonym: Internal radiation brachytherapy
has exact synonym: internal radiation
has exact synonym: radiation brachytherapy

Axiom
annotated source: internal radiation therapy
annotated property: IAO_0000115
annotated target: A type of radiation therapy in which radioactive material is placed inside the body, into a tumor or body cavity.
has db xref: NCIT:C15195

MRI of the breast
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000310
subclass of: MRI of the chest
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000310
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the breast.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the breast
has exact synonym: breast MRI
has exact synonym: breast magnetic resonance imaging

beta-lactam antibacterial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: CHEBI_27933
subclass of: antibacterial agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: CHEBI_27933
IAO_0000115: Use of an organonitrogen heterocyclic antibiotic that contains a beta-lactam ring.
date: 2019-08-29T18:00:40Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: beta-lactams therapy
has db xref: CHEBI:27933
has exact synonym: beta-lactam antibacterial drug therapy
has exact synonym: beta-lactam antibacterial drug treatment
has exact synonym: beta-lactam antibiotic agent therapy
has exact synonym: treatment with a beta-lactam antibacterial drug
has exact synonym: treatment with a beta-lactam antibacterial medication
has exact synonym: treatment with a beta-lactam antibacterial therapy
has exact synonym: treatment with a beta-lactam antibiotic agent
has exact synonym: treatment with a beta-lactam antibiotic drug
has exact synonym: treatment with a beta-lactam antibiotic medication
has exact synonym: treatment with a beta-lactam antibiotic therapy

calcium channel blocking agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38215
subclass of: receptor antagonist therapy
subclass of: calcium channel modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38215
IAO_0000115: Treatment with a pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the amount of calcium able to enter the cell. These drugs are used for their chronotropic, antihypertensive and vasodilatory effects.
date: 2019-09-27T19:41:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38215
has db xref: NCIT:C333
has exact synonym: Ca2+ channel antagonist therapy
has exact synonym: Ca2+ channel blocker therapy
has exact synonym: calcium channel antagonist drug therapy
has exact synonym: calcium channel antagonist therapy
has exact synonym: calcium channel blocker drug therapy
has exact synonym: treatment with calcium channel blocker
has exact synonym: treatment with calcium channel blocker drug
has exact synonym: treatment with calcium channel blocker medication
has exact synonym: treatment with calcium channel blocking drug
has exact synonym: treatment with calcium channel blocking medication
comment: One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.

Axiom
annotated source: calcium channel blocking agent therapy
annotated property: hasExactSynonym
annotated target: Ca2+ channel antagonist therapy
has synonym type: OMO_0003000

Axiom
annotated source: calcium channel blocking agent therapy
annotated property: hasExactSynonym
annotated target: Ca2+ channel blocker therapy
has synonym type: OMO_0003000

Axiom
annotated source: calcium channel blocking agent therapy
annotated property: comment
annotated target: One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
has db xref: CHEBI:38215

NMDA receptor antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_60643
subclass of: receptor antagonist therapy
subclass of: NMDA receptor modulator agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_60643
IAO_0000115: Treatment with a drug that inhibits the action of N-methyl-D-aspartate (NMDA) receptors.
date: 2019-10-01T19:23:17Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:60643
has exact synonym: N-methyl-D-aspartate receptor antagonist therapy
has exact synonym: NMDA receptor antagonist drug treatment
has exact synonym: NMDA receptor antagonist treatment
has exact synonym: NMDA receptor blocker therapy
has exact synonym: treatment with NMDA blockade drug
has exact synonym: treatment with NMDA blockade medication
has exact synonym: treatment with NMDA blockade therapy
has exact synonym: treatment with NMDA blockers
has exact synonym: treatment with NMDA receptor antagonist
comment: They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.

Axiom
annotated source: NMDA receptor antagonist therapy
annotated property: comment
annotated target: They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
has db xref: CHEBI:60643

ADHD agent therapy
type: Class
subclass of: central nervous system agent therapy
IAO_0000115: Use of medication for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
date: 2019-10-02T15:59:55Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: ADHD drug therapy
has exact synonym: ADHD drug treatment
has exact synonym: Attention Deficit Hyperactivity Disorder drug therapy
has exact synonym: Attention Deficit Hyperactivity Disorder drug treatment
has exact synonym: drug therapy for ADHD

Axiom
annotated source: ADHD agent therapy
annotated property: IAO_0000115
annotated target: Use of medication for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
has db xref: https://orcid.org/0000-0001-7941-2961

stimulant ADHD agent therapy
type: Class
subclass of: ADHD agent therapy
IAO_0000115: Use of stimulant medication (usually amphetamines) for treatment of Attention Deficit Hyperactivity Disorder (ADHD).
date: 2019-10-02T16:01:46Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: stimulant ADHD drug treatment
has exact synonym: stimulant Attention Deficit Hyperactivity Disorder agent therapy
has exact synonym: stimulant Attention Deficit Hyperactivity Disorder drug treatment
has exact synonym: stimulant drug therapy for ADHD
has exact synonym: stimulant drug treatment for ADHD

Axiom
annotated source: stimulant ADHD agent therapy
annotated property: IAO_0000115
annotated target: Use of stimulant medication (usually amphetamines) for treatment of Attention Deficit Hyperactivity Disorder (ADHD).
has db xref: https://orcid.org/0000-0001-7941-2961

selective serotonin reuptake inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50949
subclass of: antidepressant agent therapy
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50949
IAO_0000115: Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.
date: 2019-10-02T18:41:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50949
has db xref: NCIT:C94725
has exact synonym: SSRI drug therapy
has exact synonym: SSRI drug treatment
has exact synonym: selective serotonin reuptake inhibitor drug therapy
has exact synonym: selective serotonin reuptake inhibitor drug treatment
has exact synonym: treatment with SSRI
has exact synonym: treatment with SSRI agent
has exact synonym: treatment with selective serotonin reuptake inhibitor agent
has exact synonym: treatment with selective serotonin reuptake inhibitor drug
has exact synonym: treatment with selective serotonin reuptake inhibitor medication
has exact synonym: treatment with serotonin uptake inhibitor
comment: Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.

Axiom
annotated source: selective serotonin reuptake inhibitor therapy
annotated property: IAO_0000115
annotated target: Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.
has db xref: NCIT:C94725

Axiom
annotated source: selective serotonin reuptake inhibitor therapy
annotated property: comment
annotated target: Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.
has db xref: NCIT:C94725

colony stimulating factor agent therapy
type: Class
subclass of: biologic therapy
subclass of: blood formation agent therapy
IAO_0000115: Glycoprotein growth factors produced by monocytes, macrophages, or activated lymphocytes that stimulate the proliferation of bone marrow cells and differentiation of stem cells into colonies of granulocytes, monocytes, or macrophages. These substances act in either paracrine or autocrine fashion on marrow cells, appear to act synergistically in complex and poorly understood ways. Each appears to exert actions on several lines of progenitor cells and to influence end cell function. Treatment with colony-stimulating factors (CSF) can help the blood-forming tissue recover from the effects of chemotherapy and radiation therapy. These factors include interleukin-3 (IL-3), granulocyte colony-stimulating factor (G-CSF), macrophage colony-stimulating factor (M-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF).
date: 2019-10-08T17:41:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C387
has exact synonym: CSF agent therapy
has exact synonym: recombinant colony stimulating factor drug therapy
has exact synonym: recombinant colony-stimulating factor treatment
has exact synonym: recombinant hematopoietic colony-stimulating factor drug treatment

Axiom
annotated source: colony stimulating factor agent therapy
annotated property: IAO_0000115
annotated target: Glycoprotein growth factors produced by monocytes, macrophages, or activated lymphocytes that stimulate the proliferation of bone marrow cells and differentiation of stem cells into colonies of granulocytes, monocytes, or macrophages. These substances act in either paracrine or autocrine fashion on marrow cells, appear to act synergistically in complex and poorly understood ways. Each appears to exert actions on several lines of progenitor cells and to influence end cell function. Treatment with colony-stimulating factors (CSF) can help the blood-forming tissue recover from the effects of chemotherapy and radiation therapy. These factors include interleukin-3 (IL-3), granulocyte colony-stimulating factor (G-CSF), macrophage colony-stimulating factor (M-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF).
has db xref: NCIT:C387

Axiom
annotated source: colony stimulating factor agent therapy
annotated property: hasExactSynonym
annotated target: CSF agent therapy
has synonym type: OMO_0003000

granulocyte colony stimulating factor agent therapy
type: Class
subclass of: colony stimulating factor agent therapy
IAO_0000115: Treatment with an agent that stimulate the proliferation of bone marrow cells and differentiation of stem cells into colonies of granulocytes.
date: 2019-10-08T18:06:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C1287
has exact synonym: G-CSF treatment
has exact synonym: granulocyte-colony stimulating factor treatment therapy
has exact synonym: recombinant colony-stimulating factor 3 treatment therapy
has exact synonym: recombinant granulocyte colony stimulating factor agent therapy
has exact synonym: recombinant granulocyte colony-stimulating factor drug treatment
has exact synonym: rhG-CSF therapy

Axiom
annotated source: granulocyte colony stimulating factor agent therapy
annotated property: hasExactSynonym
annotated target: G-CSF treatment
has synonym type: OMO_0003000

Axiom
annotated source: granulocyte colony stimulating factor agent therapy
annotated property: hasExactSynonym
annotated target: rhG-CSF therapy
has synonym type: OMO_0003000

erythropoietin regulating agent therapy
type: Class
subclass of: blood formation agent therapy
IAO_0000115: Treatment with agents or medications which modulate the bone marrow's production of red blood cells.
date: 2019-10-08T18:37:29Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: erythropoietin modulating treatment

erythropoietin stimulating agent therapy
type: Class
subclass of: biologic therapy
subclass of: erythropoietin regulating agent therapy
IAO_0000115: Use of a recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein erythropoietin (Epo). Epo promotes the differentiation and maturation of hematopoietic progenitors into erythrocytes; is a mitogen and a chemoattractant for endothelial cells; stimulates activated and differentiated B-cells and enhances B-cell immunoglobulin production and proliferation; and is hypoxia-inducible.
date: 2019-10-08T18:38:34Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: erythrocyte colony stimulating factor agent therapy
has broad synonym: erythropoietin therapy
has db xref: CHEBI:81579
has db xref: NCIT:C477
has exact synonym: ESA therapy
has exact synonym: hematopoietin treatment therapy
has exact synonym: recombinant EPO treatment
has exact synonym: recombinant erythropoietin drug therapy
has exact synonym: recombinant erythropoietin treatment
has exact synonym: treatment with erythropoietin stimulating agent
has exact synonym: treatment with erythropoietin stimulating medication

Axiom
annotated source: erythropoietin stimulating agent therapy
annotated property: hasExactSynonym
annotated target: ESA therapy
has related synonym: OMO_0003000

Axiom
annotated source: erythropoietin stimulating agent therapy
annotated property: hasExactSynonym
annotated target: recombinant EPO treatment
has synonym type: OMO_0003000

erythropoietin inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_91025
subclass of: erythropoietin regulating agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_91025
IAO_0000115: Use of a drug that inhibits erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production).
date: 2019-10-08T18:49:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:91025
has exact synonym: EPO inhibitor agent therapy
has exact synonym: EPO inhibitor drug treatment
has exact synonym: erythropoietin inhibitor drug treatment
has exact synonym: treatment with erythropoietin inhibitor

Axiom
annotated source: erythropoietin inhibitor therapy
annotated property: hasExactSynonym
annotated target: EPO inhibitor agent therapy
has synonym type: OMO_0003000

Axiom
annotated source: erythropoietin inhibitor therapy
annotated property: hasExactSynonym
annotated target: EPO inhibitor drug treatment
has synonym type: OMO_0003000

antifibrinolytic agent therapy
type: Class
subclass of: coagulant agent therapy
IAO_0000115: A drug that prevents fibrinolysis or lysis of a blood clot or thrombus.
date: 2019-10-08T19:21:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:48675
has exact synonym: antifibrinolytic drug treatment

Axiom
annotated source: antifibrinolytic agent therapy
annotated property: IAO_0000115
annotated target: A drug that prevents fibrinolysis or lysis of a blood clot or thrombus.
has db xref: CHEBI:48675

desmopressin agent therapy
type: Class
subclass of: coagulant agent therapy
IAO_0000115: A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.
date: 2019-10-08T19:26:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:4450
has db xref: NCIT:C61701
has exact synonym: 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin, 1-deamino-8-D-arginine vasopressin drug treatment
has exact synonym: 1-deamino-8-D-arginine vasopressin agent therapy
has exact synonym: 1-desamino-8-D-arginine vasopressin agent therapy
has exact synonym: DDAVP agent therapy
has exact synonym: desmopresina agent therapy
has exact synonym: desmopressin drug treatment
has exact synonym: desmopressine agent therapy
has exact synonym: desmopressinum agent therapy

Axiom
annotated source: desmopressin agent therapy
annotated property: IAO_0000115
annotated target: A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.
has db xref: CHEBI:4450

surgical excision
type: Class
subclass of: surgical removal procedure
IAO_0000115: The surgical removal (cutting out) of part or all of a structure or organ.
date: 2019-12-27T17:21:50Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: excision
has db xref: NCIT:C15232
has exact synonym: abscission
has exact synonym: surgical removal

surgical resection
type: Class
subclass of: surgical excision
IAO_0000115: Surgical removal (cutting out or off) without replacement of all of a body part or structure.
date: 2019-12-27T17:45:26Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: resection

surgical extirpation
type: Class
subclass of: surgical excision
IAO_0000115: Taking or cutting out solid matter from a body part. The solid matter contained in the definition may be an abnormal byproduct of a biological function or a foreign body. It may be embedded in a body part, or in the lumen of a tubular body part. The solid matter may or may not have been previously broken into pieces.
date: 2020-01-02T19:00:34Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: extirpation

Axiom
annotated source: surgical extirpation
annotated property: IAO_0000115
annotated target: Taking or cutting out solid matter from a body part. The solid matter contained in the definition may be an abnormal byproduct of a biological function or a foreign body. It may be embedded in a body part, or in the lumen of a tubular body part. The solid matter may or may not have been previously broken into pieces.
has db xref: ICD-10-PCS

obsolete surgical enucleation
type: Class
IAO_0100001: MAXO_0009049
deprecated: true

implantation
type: Class
subclass of: MAXO_0009026
IAO_0000115: A surgical procedure that places something in the human body.
date: 2020-01-06T18:21:08Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51982

Axiom
annotated source: implantation
annotated property: IAO_0000115
annotated target: A surgical procedure that places something in the human body.
has db xref: NCIT:C51982

ablation therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: The removal of material from the surface of an object by vaporization, chipping, or other erosive process.
date: 2020-01-06T19:26:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: B978-0-12-370610-2.50011-8
has db xref: NCIT:C20985

Axiom
annotated source: ablation therapy
annotated property: IAO_0000115
annotated target: The removal of material from the surface of an object by vaporization, chipping, or other erosive process.
has db xref: B978-0-12-370610-2.50011-8

laser ablation therapy
type: Class
subclass of: ablation therapy
IAO_0000115: Removal, separation, detachment, extirpation, or eradication of a body part, pathway, or function by light amplification by stimulated emission of radiation.
date: 2020-01-06T19:30:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C111241
has exact synonym: photoablation therapy

Axiom
annotated source: laser ablation therapy
annotated property: IAO_0000115
annotated target: Removal, separation, detachment, extirpation, or eradication of a body part, pathway, or function by light amplification by stimulated emission of radiation.
has db xref: NCIT:C111241

chemical ablation
type: Class
subclass of: ablation therapy
IAO_0000115: Removal, separation, detachment, extirpation, or eradication of a body part, pathway, or function by chemical means.
date: 2020-01-06T19:35:01Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C111157

Axiom
annotated source: chemical ablation
annotated property: IAO_0000115
annotated target: Removal, separation, detachment, extirpation, or eradication of a body part, pathway, or function by chemical means.
has db xref: NCIT:C111157

cryosurgery
type: Class
subclass of: surgical procedure
subclass of: thermal ablation therapy
IAO_0000115: The use of extreme cold to damage or destroy a body part, pathway, or function. The procedure is performed using small cryogenic probes during surgery, and has recently been applied to solitary sporadic renal tumor lesions.
date: 2020-01-06T19:45:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15215
has exact synonym: cryoablation therapy
has exact synonym: cryosurgical ablation therapy

Axiom
annotated source: cryosurgery
annotated property: IAO_0000115
annotated target: The use of extreme cold to damage or destroy a body part, pathway, or function. The procedure is performed using small cryogenic probes during surgery, and has recently been applied to solitary sporadic renal tumor lesions.
has db xref: NCIT:C15215

thermal ablation therapy
type: Class
subclass of: ablation therapy
IAO_0000115: Thermal ablation refers to the destruction of tissue by extreme hyperthermia or hypothermia.
date: 2020-01-06T19:50:11Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15670

Axiom
annotated source: thermal ablation therapy
annotated property: IAO_0000115
annotated target: Thermal ablation refers to the destruction of tissue by extreme hyperthermia or hypothermia.
has db xref: NCIT:C15670

pain management
type: Class
subclass of: therapeutic procedure
IAO_0000115: The management of pain by interventional procedures, pharmacotherapy, physical therapy, psychological counseling, or complementary and alternative medical therapies designed to treat or alleviate pain.
date: 2020-01-08T17:26:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: pain therapy

hydrotherapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: Hydrotherapy is the external or internal use of water in any of its forms (water, ice, steam) for health promotion or treatment of various diseases with various temperatures, pressure, duration, and site.
date: 2020-01-08T17:32:42Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: OMIT:0008013
has db xref: PMID:24926444
has exact synonym: hydropathy
has exact synonym: hydrotherapy treatment
has exact synonym: water therapy
has narrow synonym: water cure

Axiom
annotated source: hydrotherapy
annotated property: IAO_0000115
annotated target: Hydrotherapy is the external or internal use of water in any of its forms (water, ice, steam) for health promotion or treatment of various diseases with various temperatures, pressure, duration, and site.
has db xref: PMID:24926444

thermal hydrotherapy
type: Class
subclass of: pain management
subclass of: hydrotherapy
IAO_0000115: Thermal hydrotherapy uses external or internal use of water in any of its forms (water, ice, steam) at temperatures above or below room temperature for health promotion or treatment of various diseases with various temperatures, pressure, duration, and site.
date: 2020-01-08T17:39:29Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hydro-thermal therapy
has exact synonym: hydrothermal therapy
has exact synonym: thermal water therapy
has narrow synonym: bathing in thermal waters

therapeutic irrigation
type: Class
subclass of: hydrotherapy
IAO_0000115: Washing out a hollow organ (especially the stomach) by flushing with a fluid.
date: 2020-01-08T17:42:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38068
has db xref: OMIT:0008013
has exact synonym: lavage

Axiom
annotated source: therapeutic irrigation
annotated property: IAO_0000115
annotated target: Washing out a hollow organ (especially the stomach) by flushing with a fluid.
has db xref: NCIT:C38068

warm water immersion therapy
type: Class
subclass of: thermal hydrotherapy
IAO_0000115: Therapy where a substantial part of the body is immersed in warm water to produce a variety of therapeutic effects.
date: 2020-01-08T18:05:56Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hot bath therapy
has exact synonym: warm water bath therapy
has narrow synonym: hyperthermic immersion therapy
has narrow synonym: warm water shower therapy

Axiom
annotated source: warm water immersion therapy
annotated property: IAO_0000115
annotated target: Therapy where a substantial part of the body is immersed in warm water to produce a variety of therapeutic effects.
has db xref: PMID:24926444

cold water immersion therapy
type: Class
subclass of: thermal hydrotherapy
IAO_0000115: Therapy where a substantial part of the body is immersed in cold water to produce a variety of therapeutic effects.
date: 2020-01-08T18:06:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: CWI therapy
has exact synonym: ice bath therapy

Axiom
annotated source: cold water immersion therapy
annotated property: hasExactSynonym
annotated target: CWI therapy
has synonym type: OMO_0003000

contrast water therapy
type: Class
subclass of: thermal hydrotherapy
IAO_0000115: A form of treatment where a limb or significant portion of the body is immersed in hot water immediately followed by the immersion into cold water. This procedure is repeated several times.
date: 2020-01-08T18:06:31Z
creator: http://orcid.org/0000-0001-7941-2961

aquatic exercise therapy
type: Class
subclass of: physical therapy
subclass of: hydrotherapy
IAO_0000115: Therapy occuring in a pool or bath which is a low-impact activity and takes the pressure off your bones, joints, and muscles.
date: 2020-01-08T18:07:42Z
creator: http://orcid.org/0000-0001-7941-2961

breast duct lavage
type: Class
subclass of: therapeutic irrigation
IAO_0000115: A minimally-invasive procedure that permits sampling of breast ductal fluids for cytopathologic analysis.
date: 2020-01-08T19:03:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51969

Axiom
annotated source: breast duct lavage
annotated property: IAO_0000115
annotated target: A minimally-invasive procedure that permits sampling of breast ductal fluids for cytopathologic analysis.
has db xref: NCIT:C51969

bronchoaveolar lavage
type: Class
subclass of: therapeutic irrigation
IAO_0000115: Washing out the bronchi and alveoli by flushing with a fluid.
date: 2020-01-08T19:03:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51913

Axiom
annotated source: bronchoaveolar lavage
annotated property: IAO_0000115
annotated target: Washing out the bronchi and alveoli by flushing with a fluid.
has db xref: NCIT:C51913

peritoneal lavage
type: Class
subclass of: therapeutic irrigation
IAO_0000115: A minimally invasive procedure that permits sampling of peritoneal fluid for cytopathologic analysis.
date: 2020-01-08T19:03:46Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C159340
has exact synonym: peritoneal washing

Axiom
annotated source: peritoneal lavage
annotated property: IAO_0000115
annotated target: A minimally invasive procedure that permits sampling of peritoneal fluid for cytopathologic analysis.
has db xref: NCIT:C159340

nasal lavage
type: Class
subclass of: therapeutic irrigation
IAO_0000115: The process in which the nasal cavity is washed to flush out mucus and debrise from the nose and sinuses with water or saline.
date: 2020-01-08T19:04:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: nasal irrigation
has exact synonym: nasal washing

therapeutic procedure avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: therapeutic procedure
IAO_0000115: Avoid the administration or use of therapeutic procedure.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-12T20:39:14Z
has exact synonym: avoid therapeutic procedure
has exact synonym: avoiding therapeutic procedure

diagnostic procedure avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: diagnostic procedure
IAO_0000115: Avoid the administration or use of diagnostic procedure.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-12T20:39:14Z
has exact synonym: avoid diagnostic procedure
has exact synonym: avoiding diagnostic procedure

preventative therapy avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: preventative therapy
IAO_0000115: Avoid the administration or use of preventative therapy.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-12T20:39:14Z
has exact synonym: avoid preventative therapy
has exact synonym: avoiding preventative therapy

medical device implantation
type: Class
subclass of: implantation
IAO_0000115: The implantation of a piece of mechanical or electronic equipment that is useful for prevention, diagnosis, monitoring, or treatment of disease or other conditions.
date: 2020-01-20T14:58:18Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: ERO:0001092
has db xref: NCIT:C16830
has exact synonym: implantation of a medical device
has exact synonym: insertion of a medical device
has exact synonym: insertion of a therapeutic device
has exact synonym: therapeutic device implantation
has narrow synonym: medical instrument implantation
has narrow synonym: medical machine implantation

implantable cardioverter-defibrillator placement
type: Class
subclass of: MAXO_0009033
IAO_0000115: Implantation of a battery-powered device that is placed under the skin (typically in the left upper chest) with electrode wires that lead into the heart (typically lodging in the apex or septum of the right ventricle). The device can detect abnormal heart rhythms and deliver low-energy or high-energy shocks to interrupt malignant arrhythmia and thereby prevent sudden death.
date: 2020-01-20T16:54:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIt:C93238
has db xref: UMLS_CUI:C0162589
has exact synonym: ICD placement
has exact synonym: automated implantable cardioverter defibrillator placement
has exact synonym: implantable cardioverter-defibrillator implantation

Axiom
annotated source: implantable cardioverter-defibrillator placement
annotated property: hasExactSynonym
annotated target: ICD placement
has synonym type: OMO_0003000

surgical denervation
type: Class
subclass of: surgical procedure
IAO_0000115: The resection or complete surgical removal of a nerve.
date: 2020-01-20T17:09:07Z
creator: http://orcid.org/0000-0001-7941-2961

left cardiac sympathetic denervation
type: Class
subclass of: surgical denervation
IAO_0000115: Left cardiac sympathetic denervation (LCSD) is a surgical antiadrenergic intervention with a strong antiarrhythmic effect. LCSD consists in the removal of the left thoracic sympathetic chain and paravertebral ganglia from T1 to T4.
date: 2020-01-20T17:11:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: PMID:30972341
has exact synonym: LCSD

Axiom
annotated source: left cardiac sympathetic denervation
annotated property: IAO_0000115
annotated target: Left cardiac sympathetic denervation (LCSD) is a surgical antiadrenergic intervention with a strong antiarrhythmic effect. LCSD consists in the removal of the left thoracic sympathetic chain and paravertebral ganglia from T1 to T4.
has db xref: PMID:30972341

Axiom
annotated source: left cardiac sympathetic denervation
annotated property: hasExactSynonym
annotated target: LCSD
has synonym type: OMO_0003000

orthopedic procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: Any procedure relating to the branch of medicine dealing with the correction of deformities of bones or muscles.
date: 2020-01-20T17:50:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D019637
has exact synonym: orthopaedic procedure

orthopedic surgeon evaluation
type: Class
subclass of: orthopedic procedure
subclass of: medical specialist evaluation
IAO_0000115: Assessment by a surgeon who focuses on the preservation, investigation and restoration of the form and function of the extremities, spine and associated structures by medical, surgical and physical means. This specialist is involved with the care of patients whose musculoskeletal problems include congenital deformities, trauma, infections, tumors, metabolic disturbances of the musculoskeletal system, deformities, injuries and degenerative diseases of the spine, hands, feet, knee, hip, shoulder and elbow in children and adults. An orthopaedic surgeon is also concerned with primary and secondary muscular problems and the effects of central or peripheral nervous system lesions of the musculoskeletal system.
date: 2020-01-20T17:50:52Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009062
has exact synonym: consultation with orthopedic surgeon
has exact synonym: examination by orthopedist
has exact synonym: orthopaedic consult
has exact synonym: orthopedic consult
has exact synonym: orthopedic surgeon consultation
has exact synonym: orthopedic surgeon referral
has exact synonym: orthopedist consultation
has exact synonym: referral to orthopedic surgeon
has exact synonym: referral to orthopedist

Axiom
annotated source: orthopedic surgeon evaluation
annotated property: IAO_0000115
annotated target: Assessment by a surgeon who focuses on the preservation, investigation and restoration of the form and function of the extremities, spine and associated structures by medical, surgical and physical means. This specialist is involved with the care of patients whose musculoskeletal problems include congenital deformities, trauma, infections, tumors, metabolic disturbances of the musculoskeletal system, deformities, injuries and degenerative diseases of the spine, hands, feet, knee, hip, shoulder and elbow in children and adults. An orthopaedic surgeon is also concerned with primary and secondary muscular problems and the effects of central or peripheral nervous system lesions of the musculoskeletal system.
has db xref: abms.org

orthopedic surgery
type: Class
equivalent class: Class
  intersection of: surgery by body site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001434
subclass of: orthopedic procedure
subclass of: MAXO_0001508
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001434
IAO_0000115: Any surgical procedure conducted on the skeletal system.
date: 2020-01-20T17:51:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16186
has exact synonym: orthopedic surgical procedure
has exact synonym: orthopedics surgery
has exact synonym: skeletal system surgical procedure

obsolete orthopedic consultation
type: Class
IAO_0100001: orthopedic surgeon evaluation
deprecated: true

orthotic services
type: Class
subclass of: orthopedic procedure
IAO_0000115: Orthotic services provide prescription insoles, braces, splints, callipers, footwear, spinal jackets and helmets which help people recover from or avoid injury, or live with lifelong conditions.
date: 2020-01-20T18:01:00Z
creator: http://orcid.org/0000-0001-7941-2961

orthotic device usage
type: Class
subclass of: orthotic services
IAO_0000115: The recommendation of the use of an orthosis or multiple orthoses, which are externally applied device used to modify the structural and functional characteristics of the neuromuscular and skeletal system.
date: 2020-01-20T18:02:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: PMID:26835739
has exact synonym: orthoses usage

Axiom
annotated source: orthotic device usage
annotated property: IAO_0000115
annotated target: The recommendation of the use of an orthosis or multiple orthoses, which are externally applied device used to modify the structural and functional characteristics of the neuromuscular and skeletal system.
has db xref: PMID:26835739

medical professional evaluation
type: Class
subclass of: diagnostic procedure
IAO_0000115: A procedure where a healthcare provider, who was not previously involved in a patient's treatment, reviews a patient's medical history, examines the patient, and makes recommendations as to care and treatment.
date: 2020-01-20T18:30:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: medical professional consultation
has exact synonym: medical professional examination
comment: An appraisal or evaluation of a patient's condition by a clinician that is based on a physical exam, medical history, and the patient's account of symptoms.

Axiom
annotated source: medical professional evaluation
annotated property: comment
annotated target: An appraisal or evaluation of a patient's condition by a clinician that is based on a physical exam, medical history, and the patient's account of symptoms.
has db xref: PMID:19567008
comment: NCIT:C25305

bone lengthening procedure
type: Class
subclass of: orthopedic surgery
IAO_0000115: Increase in the longest dimension of a bone to correct anatomical deficiencies, congenital, traumatic, or as a result of disease. The lengthening is not restricted to long bones. The usual surgical methods are internal fixation and distraction.
date: 2020-01-21T19:47:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D001852
has db xref: OMIT:0003210
has exact synonym: limb lengthening procedure
has narrow synonym: leg lengthening

Axiom
annotated source: bone lengthening procedure
annotated property: IAO_0000115
annotated target: Increase in the longest dimension of a bone to correct anatomical deficiencies, congenital, traumatic, or as a result of disease. The lengthening is not restricted to long bones. The usual surgical methods are internal fixation and distraction.
has db xref: MeSH:D001852

Ilizarov procedure
type: Class
subclass of: bone lengthening procedure
IAO_0000115: A bone fixation technique using an external fixator for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis.
date: 2020-01-21T19:52:10Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D018889
has exact synonym: Ilizarov technique

Axiom
annotated source: Ilizarov procedure
annotated property: IAO_0000115
annotated target: A bone fixation technique using an external fixator for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis.
has db xref: MeSH:D018889

distraction osteogenesis
type: Class
subclass of: bone lengthening procedure
IAO_0000115: Bone lengthening by gradual mechanical distraction. An external fixation device produces the distraction across the bone plate. The technique was originally applied to long bones but in recent years the method has been adapted for use with mandibular implants in maxillofacial surgery.
date: 2020-01-21T20:01:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D019857

Axiom
annotated source: distraction osteogenesis
annotated property: IAO_0000115
annotated target: Bone lengthening by gradual mechanical distraction. An external fixation device produces the distraction across the bone plate. The technique was originally applied to long bones but in recent years the method has been adapted for use with mandibular implants in maxillofacial surgery.
has db xref: MeSH:D019857

clinical assessment
type: Class
subclass of: diagnostic procedure
IAO_0000115: A measurement performed in a clinical setting using clinician's observations and instrument data to inform patient care and research.
date: 2020-01-21T20:29:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CMO:0000000
has db xref: PMID:2647562
has exact synonym: clinical measurement

Axiom
annotated source: clinical assessment
annotated property: IAO_0000115
annotated target: A measurement performed in a clinical setting using clinician's observations and instrument data to inform patient care and research.
has db xref: PMID:2647562

body temperature measurement
type: Class
subclass of: clinical assessment
IAO_0000115: An assessment of body temperature.
date: 2020-01-21T20:35:51Z
creator: http://orcid.org/0000-0001-7941-2961
date: 2023-04-11T12:00:00Z
has db xref: CMO:0000015
has db xref: NCBIBook:NBK331

vital signs measurement
type: Class
subclass of: clinical assessment
IAO_0000115: The act of assessing an individual's current temperature, heart rate, respiratory rate, pulse oxygenation, and blood pressure.
date: 2020-01-21T20:43:33Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49672
has exact synonym: VSTEST
has exact synonym: vital signs assessment

Axiom
annotated source: vital signs measurement
annotated property: IAO_0000115
annotated target: The act of assessing an individual's current temperature, heart rate, respiratory rate, pulse oxygenation, and blood pressure.
has db xref: NCIT:C49672

Axiom
annotated source: vital signs measurement
annotated property: hasExactSynonym
annotated target: VSTEST
has synonym type: OMO_0003000

heart rate measurement
type: Class
subclass of: vital signs measurement
IAO_0000115: An assessment of the number of heartbeats per unit time, usually expressed as beats per minute.
date: 2020-01-21T20:47:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CMO:0000002
has db xref: NCIT:C49677
has exact synonym: HR measurement
has exact synonym: heart rate assessment

Axiom
annotated source: heart rate measurement
annotated property: hasExactSynonym
annotated target: HR measurement
has synonym type: OMO_0003000

pulse assessment
type: Class
subclass of: vital signs measurement
IAO_0000115: Assessment and recording of arterial pulses in any of a number of locations. The observer should note its intensity, rate, rhythm, and if any blood vessel tenderness, tortuosity, or nodularity exists.
date: 2020-01-21T20:59:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCBIBook:NBK350

respiratory rate assessment
type: Class
subclass of: vital signs measurement
IAO_0000115: The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute.
date: 2020-01-21T21:04:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CMO:0000289
has db xref: NCIT:C49678

Axiom
annotated source: respiratory rate assessment
annotated property: IAO_0000115
annotated target: The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute.
has db xref: NCIT:C49678

diagnostic procedure of cardiovascular system
type: Class
equivalent class: Class
  intersection of: diagnostic procedure by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004535
subclass of: MAXO_0001398
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004535
IAO_0000115: Procedure to evaluate the structure and/or function of the cardiovascular system.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-21T21:09:50Z
has db xref: CMO:0000001
has db xref: NCIT:C100084
has exact synonym: cardiovascular diagnostic procedure
has exact synonym: cardiovascular system diagnostic procedure

blood pressure measurement
type: Class
subclass of: clinical assessment
subclass of: diagnostic procedure of cardiovascular system
IAO_0000115: Measurement of the pressure on the walls of the vessels as blood moves around the body. Systolic blood pressure is the pressure when the heart beats – while the heart muscle is contracting (squeezing) and pumping oxygen-rich blood into the blood vessels. Diastolic blood pressure is the pressure on the blood vessels when the heart muscle relaxes. The diastolic pressure is always lower than the systolic pressure.
date: 2020-01-21T21:13:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CMO:0000003
has db xref: NCBIBook:NBK279251
has exact synonym: blood pressure assessment
has exact synonym: blood pressure monitoring

auscultatory blood pressure measurement
type: Class
subclass of: noninvasive blood pressure measurement
IAO_0000115: Monitoring blood pressure with a sphygmomanometer and a stethoscope to hear blood flow.
date: 2020-01-22T15:29:56Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MMO:0000055
has db xref: NCIT:C69318
has db xref: PMID:20937442
has db xref: VSO:0000001
has exact synonym: ausculatory sphygmomanometer blood pressure measurement
has exact synonym: auscultatory blood pressure measurement process
has exact synonym: auscultatory blood pressure monitoring
comment: Although the auscultatory method using mercury sphygmomanometer is regarded as the ‘gold standard’ for office blood pressure measurement, widespread implementation of the ban in use of mercury sphygmomanometers continues to diminish the role of this technique.

Axiom
annotated source: auscultatory blood pressure measurement
annotated property: comment
annotated target: Although the auscultatory method using mercury sphygmomanometer is regarded as the ‘gold standard’ for office blood pressure measurement, widespread implementation of the ban in use of mercury sphygmomanometers continues to diminish the role of this technique.
has db xref: PMID:20937442

oscillometric blood pressure measurement
type: Class
subclass of: noninvasive blood pressure measurement
IAO_0000115: A blood pressure measurement using a sphygmomanometer and an electronic pressure sensor (transducer) that detects blood flow by the presence of oscillations in the cuff pressure.
date: 2020-01-22T20:49:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C69319
has db xref: PMID:20937442
has db xref: VSO:0000026

noninvasive blood pressure measurement
type: Class
subclass of: blood pressure measurement
IAO_0000115: A method for monitoring blood pressure without requiring instruments introduced into the body.
date: 2020-01-22T21:01:49Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C69319
has db xref: PMID:20937442
has db xref: VSO:0000024
has exact synonym: non-invasive blood presure measurement

invasive blood pressure measurement
type: Class
subclass of: blood pressure measurement
IAO_0000115: An intra-arterial method of monitoring blood pressure.
date: 2020-01-22T21:18:39Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: VSO:0000023

therapeutic procedure of respiratory system
type: Class
equivalent class: Class
  intersection of: therapeutic procedure by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001004
subclass of: therapeutic procedure by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001004
IAO_0000115: All manners of treatment to bring respiratory system back to its normal state.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-23T15:55:17Z
has db xref: NCIT:C15322
has exact synonym: respiratory system therapeutic procedure
has exact synonym: respiratory therapy

airway management
type: Class
subclass of: therapeutic procedure of respiratory system
IAO_0000115: A set of maneuvers or medical procedures performed to prevent and relieve airway obstruction. This ensures an open pathway for gas exchange between a patient's lungs and the atmosphere.
date: 2020-01-23T15:56:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D058109

Axiom
annotated source: airway management
annotated property: IAO_0000115
annotated target: A set of maneuvers or medical procedures performed to prevent and relieve airway obstruction. This ensures an open pathway for gas exchange between a patient's lungs and the atmosphere.
has db xref: PMID:18675024

endotracheal extubation
type: Class
subclass of: airway management
subclass of: extubation procedure
IAO_0000115: Removal of an endotracheal tube from the patient.
date: 2020-01-23T16:07:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D060666
has db xref: NCIT:C50819
has exact synonym: airway extubation
has exact synonym: tracheal extubation

Axiom
annotated source: endotracheal extubation
annotated property: IAO_0000115
annotated target: Removal of an endotracheal tube from the patient.
has db xref: MeSH:D060666

endotracheal intubation
type: Class
subclass of: airway management
subclass of: intubation procedure
IAO_0000115: A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia.
date: 2020-01-23T16:16:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D007442
has db xref: NCIT:C116648
has exact synonym: airway intubation
has exact synonym: intratracheal intubation
has exact synonym: tracheal intubation

Axiom
annotated source: endotracheal intubation
annotated property: IAO_0000115
annotated target: A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia.
has db xref: MeSH:D007442

artificial respiration
type: Class
subclass of: airway management
IAO_0000115: Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have respiratory insufficiency to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
date: 2020-01-23T16:34:17Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: artificial ventilation
has exact synonym: mechanical ventilation

tracheostomy
type: Class
equivalent class: Class
  intersection of: ostomy surgical procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0007196
subclass of: airway management
subclass of: ostomy surgical procedure
subclass of: MAXO_0001443
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007196
IAO_0000115: Surgical formation of an opening into the trachea through the neck, or the opening so created.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-23T16:48:07Z
has db xref: MeSH:D014140
has db xref: PMID:32644550
has exact synonym: trach
has exact synonym: tracheotomy
comment: Tracheostomy and tracheotomy are sometimes used interchangeably, but tracheotomy is simply a surgical incision of the trachea.

mask ventilation
type: Class
subclass of: noninvasive ventilation
IAO_0000115: A manual method for maintaining oxygenation using a mask.
date: 2020-01-23T17:41:09Z
creator: http://orcid.org/0000-0001-7941-2961
has narrow synonym: bag-mask ventilation

noninvasive ventilation
type: Class
subclass of: artificial respiration
IAO_0000115: Techniques for administering artificial respiration without the need for intratracheal intubation.
date: 2020-01-23T17:52:50Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D063087
has exact synonym: non-invasive ventilation

Axiom
annotated source: noninvasive ventilation
annotated property: IAO_0000115
annotated target: Techniques for administering artificial respiration without the need for intratracheal intubation.
has db xref: MeSH:D063087

high-frequency ventilation
type: Class
subclass of: positive controlled ventilation
IAO_0000115: Ventilatory support system using frequencies from 60-900 cycles/min or more. Three types of systems have been distinguished on the basis of rates, volumes, and the system used.
date: 2020-01-23T17:57:32Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D006612
has exact synonym: high frequency oscillation ventilation
has exact synonym: high frequency positive pressure ventilation

Axiom
annotated source: high-frequency ventilation
annotated property: IAO_0000115
annotated target: Ventilatory support system using frequencies from 60-900 cycles/min or more. Three types of systems have been distinguished on the basis of rates, volumes, and the system used.
has db xref: MeSH:D006612

liquid ventilation
type: Class
subclass of: artificial respiration
IAO_0000115: A technique of mechanical ventilation in which the lungs are insufflated with an oxygenated perfluorochemical liquid rather than an oxygen-containing gas mixture.
date: 2020-01-23T18:01:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D021061
has exact synonym: liquid-assisted ventilation

Axiom
annotated source: liquid ventilation
annotated property: IAO_0000115
annotated target: A technique of mechanical ventilation in which the lungs are insufflated with an oxygenated perfluorochemical liquid rather than an oxygen-containing gas mixture.
has db xref: PMID:22043370

positive controlled ventilation
type: Class
subclass of: artificial respiration
IAO_0000115: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.
date: 2020-01-23T18:06:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D011175
has exact synonym: positive control ventilation
has exact synonym: positive controlled respiration
has exact synonym: positive end expiratory pressure technique
has exact synonym: positive pressure respiration
has exact synonym: positive pressure ventilation
has exact synonym: positive-controlled ventilation
has exact synonym: positive-pressure respiration
has exact synonym: positive-pressure ventilation

Axiom
annotated source: positive controlled ventilation
annotated property: IAO_0000115
annotated target: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.
has db xref: MeSH:D011175

negative-pressure respiration
type: Class
subclass of: artificial respiration
IAO_0000115: Assisted ventilation by applying intermittent subatmospheric pressure around the thorax, abdomen, or airway and periodically expand the chest wall and inflate the lungs.
date: 2020-01-23T18:22:46Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: iron lung ventilation
has broad synonym: portalung ventilation
has db xref: MeSH:D015919
has exact synonym: negative-pressure ventilation

obsolete bilevel positive airway pressure ventilation
type: Class
IAO_0100001: biphasic positive airway pressure ventilation
deprecated: true

continuous positive airway pressure ventilation
type: Class
subclass of: positive controlled ventilation
IAO_0000115: A form of non-invasive mechanical pressure support ventilation that uses a continuous positive airway pressure level to support spontaneous breathing activity.
date: 2020-01-23T18:31:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D045422
has db xref: NCIT:C124040
has exact synonym: CPAP ventilation
has narrow synonym: nCPAP ventilation
has narrow synonym: nasal continuous positive airway pressure ventilation

Axiom
annotated source: continuous positive airway pressure ventilation
annotated property: IAO_0000115
annotated target: A form of non-invasive mechanical pressure support ventilation that uses a continuous positive airway pressure level to support spontaneous breathing activity.
has db xref: NCIT:C124040

Axiom
annotated source: continuous positive airway pressure ventilation
annotated property: hasExactSynonym
annotated target: CPAP ventilation
has synonym type: OMO_0003000

Axiom
annotated source: continuous positive airway pressure ventilation
annotated property: hasNarrowSynonym
annotated target: nCPAP ventilation
has synonym type: OMO_0003000

postural drainage
type: Class
subclass of: chest physiotherapy
IAO_0000115: A rehabilitation therapy for removal of copious mucus secretion from the lung of patients with diseases. The patient's head is placed in a downward incline (so the trachea is inferior to the affected area) for 15 to 20 minute sessions.
date: 2020-01-23T19:45:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D015916
has exact synonym: postural respiratory drainage
has exact synonym: pulmonary postural drainage

chest wall oscillation
type: Class
subclass of: chest physiotherapy
IAO_0000115: A respiratory support system used to remove mucus and clear airway by oscillating pressure on the chest.
date: 2020-01-23T20:18:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D035641
has exact synonym: external chest wall oscillation
has exact synonym: high-frequency chest compression
has exact synonym: high-frequency chest wall oscillation

Axiom
annotated source: chest wall oscillation
annotated property: IAO_0000115
annotated target: A respiratory support system used to remove mucus and clear airway by oscillating pressure on the chest.
has db xref: MeSH:D035641

extracorporeal membrane oxygenation
type: Class
subclass of: therapeutic procedure of respiratory system
IAO_0000115: Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger.
date: 2020-01-23T20:23:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D015199
has exact synonym: ECLS treatment
has exact synonym: ECMO treatment
has exact synonym: extracorporeal life support

Axiom
annotated source: extracorporeal membrane oxygenation
annotated property: IAO_0000115
annotated target: Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger.
has db xref: MeSH:D015199

Axiom
annotated source: extracorporeal membrane oxygenation
annotated property: hasExactSynonym
annotated target: ECLS treatment
has synonym type: OMO_0003000

Axiom
annotated source: extracorporeal membrane oxygenation
annotated property: hasExactSynonym
annotated target: ECMO treatment
has synonym type: OMO_0003000

chest physiotherapy
type: Class
subclass of: physical therapy
subclass of: therapeutic procedure of respiratory system
IAO_0000115: Chest physical therapy (CPT or Chest PT) is an airway clearance technique (ACT) to drain the lungs, and may include percussion (clapping), vibration, deep breathing, and huffing or coughing.
date: 2020-01-23T20:32:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: CPT
has exact synonym: Chest PT
has exact synonym: chest physical therapy

intubation procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: The insertion of a cannula or tube into a hollow body organ.
date: 2020-01-23T20:44:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: ERO:0001108
has db xref: MeSH:D007440
has db xref: NCIT:C37981

Axiom
annotated source: intubation procedure
annotated property: IAO_0000115
annotated target: The insertion of a cannula or tube into a hollow body organ.
has db xref: NCIT:C37981

extubation procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: The removal of a previously inserted tube from a hollow organ or passageway, often from the airway.
date: 2020-01-23T20:48:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C50819

Axiom
annotated source: extubation procedure
annotated property: IAO_0000115
annotated target: The removal of a previously inserted tube from a hollow organ or passageway, often from the airway.
has db xref: NCIT:C50819

fetal ultrasonography
type: Class
subclass of: ultrasonography procedure
IAO_0000115: Use of medical ultrasonography in pregnancy where sound waves are used to create a real-time visual image of the developing fetus in the uterus. Imaging can include the mother's ovaries and uterus as well.
date: 2020-01-24T19:29:52Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: fetal ultrasound
has exact synonym: obstetric sonography
has exact synonym: obstetric ultrasonography
has exact synonym: obstetric ultrasound
has exact synonym: prenatal ultrasound procedure

cognitive and behavioral intervention avoidance
type: Class
subclass of: cognitive and behavioral intervention
IAO_0000115: A clinical recommendation to avoid or refrain from certain behaviors in order to maintain health or ameliorate symptoms.
date: 2020-01-29T17:35:05Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: behavior avoidance for therapeutic purposes

examination by clinical professional
type: Class
subclass of: medical professional evaluation
subclass of: clinical assessment
IAO_0000115: A direct assessment of a patient's condition by a clinical health professional that is based on a physical exam, medical history, and the patient's account of symptoms.
date: 2020-03-04T17:09:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C25305
has exact synonym: clinical examination
has exact synonym: medical examination
has narrow synonym: examination by physician

Axiom
annotated source: examination by clinical professional
annotated property: IAO_0000115
annotated target: A direct assessment of a patient's condition by a clinical health professional that is based on a physical exam, medical history, and the patient's account of symptoms.
has db xref: PMID:19567008

physical examination
type: Class
subclass of: examination by clinical professional
IAO_0000115: A systemic evaluation of the body and its functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
date: 2020-03-04T17:45:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: physical exam

Axiom
annotated source: physical examination
annotated property: IAO_0000115
annotated target: A systemic evaluation of the body and its functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
has db xref: NCIT:C20989

prenatal examination
type: Class
subclass of: physical examination
subclass of: obstetrics and gynecology procedure
IAO_0000115: A test or diagnostic examination to assess the health status of the mother and well being of the fetus.
date: 2021-02-11T22:00:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92714
has exact synonym: antenatal examination

prenatal genetic testing
type: Class
subclass of: genetic testing
subclass of: prenatal examination
IAO_0000115: Testing of fetal DNA during pregnancy to determine if the fetus has chromosomal aberrations, fetal aneuploidy, or other detectable genetic disorders.
date: 2020-03-17T18:55:32Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: fetal genetic testing
has exact synonym: foetal genetic screening
has exact synonym: prenatal genetic screening

genetic carrier screening
type: Class
subclass of: genetic testing
IAO_0000115: A genetic test to whether a healthy person harbors a recessive mutation in one of their copies of a gene or genes.
date: 2020-03-17T20:04:20Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: carrier screening
has narrow synonym: expanded carrier screening

noninvasive prenatal testing
type: Class
subclass of: prenatal genetic testing
IAO_0000115: A test that analyzes small fragments of DNA that are circulating in a pregnant woman’s blood to determine the risk that the fetus will be born with genetic abnormalities.
date: 2020-03-17T20:22:26Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: NIPT
has exact synonym: cell free fetal DNA testing
has exact synonym: noninvasive prenatal screening

Axiom
annotated source: noninvasive prenatal testing
annotated property: hasExactSynonym
annotated target: NIPT
has synonym type: OMO_0003000

obsolete prenatal molecular genetic testing
type: Class
deprecated: true

molecular genetic testing
type: Class
subclass of: genetic testing
IAO_0000115: A diverse set of techniques used to identify the molecular basis of genetic disease. Examples of molecular genetic tests include: genotyping to detect specific pathogenic variants; sequencing of a gene to detect pathogenic variants; amplification or hybridization methods (e.g., qPCR, array CGH, MLPA) to detect copy number variants involving one or more genes; methylation-specific techniques to detect epigenetic changes that influence gene expression; and exome and genome sequencing.
date: 2020-03-18T19:19:07Z
creator: http://orcid.org/0000-0001-7941-2961

amniocentisis
type: Class
subclass of: prenatal genetic testing
subclass of: surgical aspiration procedure
IAO_0000115: A prenatal diagnostic procedure in which a small sample of amniotic fluid is removed from the uterus by a needle inserted into the abdomen. This procedure is used to detect various genetic abnormalities in the fetus and/or the sex of the fetus.
date: 2020-03-19T19:24:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C52009

Axiom
annotated source: amniocentisis
annotated property: IAO_0000115
annotated target: A prenatal diagnostic procedure in which a small sample of amniotic fluid is removed from the uterus by a needle inserted into the abdomen. This procedure is used to detect various genetic abnormalities in the fetus and/or the sex of the fetus.
has db xref: NCIT:C52009

surgical aspiration procedure
type: Class
subclass of: surgical procedure
IAO_0000115: Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue.
date: 2020-03-19T19:39:48Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: surgical aspiration procedure
annotated property: IAO_0000115
annotated target: Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue.
has db xref: NCIT:C15631

chorionic villus sampling
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0007106
subclass of: prenatal genetic testing
subclass of: clinical biopsy by site
subclass of: whole body examination
subclass of: MAXO_0001443
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007106
IAO_0000115: A prenatal test in which a sample of chorionic villi is removed from the placenta for testing. The sample can be taken through the cervix (transcervical) or the abdominal wall (transabdominal). Mayo Clinic
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-06-23T20:39:14Z
date: 2020-03-19T19:51:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92755
has exact synonym: CVS
has exact synonym: chorionic villus biopsy
comment: The biopsy of placental tissue containing the chorionic villi from the maternal uterus in early pregnancy to diagnose fetal genetic defects.

Axiom
annotated source: chorionic villus sampling
annotated property: hasExactSynonym
annotated target: CVS
has synonym type: OMO_0003000

Axiom
annotated source: chorionic villus sampling
annotated property: comment
annotated target: The biopsy of placental tissue containing the chorionic villi from the maternal uterus in early pregnancy to diagnose fetal genetic defects.
has db xref: NCIT:C92755

bacterial vaginosis screening
type: Class
subclass of: prenatal examination
IAO_0000115: A procedure conducted during pregnancy for the presence of Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Mobiluncus, Prevotella and anaerobic bacteria.
date: 2020-03-19T20:17:55Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92740
has exact synonym: BV testing

Axiom
annotated source: bacterial vaginosis screening
annotated property: hasExactSynonym
annotated target: BV testing
has synonym type: OMO_0003000

fetal fibronectin testing
type: Class
subclass of: prenatal examination
IAO_0000115: A test for the presence of fetal fibronectin in the cervico-vaginal area that is used to predict preterm birth.
date: 2020-03-19T20:22:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92786
has exact synonym: FBNCTFT
has exact synonym: fFN testing
has exact synonym: fetal fibronectin assessment

Axiom
annotated source: fetal fibronectin testing
annotated property: IAO_0000115
annotated target: A test for the presence of fetal fibronectin in the cervico-vaginal area that is used to predict preterm birth.
has db xref: NCIT:C92786

Axiom
annotated source: fetal fibronectin testing
annotated property: hasExactSynonym
annotated target: FBNCTFT
has synonym type: OMO_0003000

Axiom
annotated source: fetal fibronectin testing
annotated property: hasExactSynonym
annotated target: fFN testing
has synonym type: OMO_0003000

prenatal group B streptococcus screening
type: Class
subclass of: prenatal examination
subclass of: infectious disease screening
IAO_0000115: Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection.
date: 2020-03-19T20:47:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92805
has exact synonym: GBS
has exact synonym: beta-hemolytic strep culture screening
has exact synonym: broup B Beta-hemolytic streptococcus screening
has exact synonym: group B strep screening

Axiom
annotated source: prenatal group B streptococcus screening
annotated property: IAO_0000115
annotated target: Screening with a swab from the vaginal and rectal areas in late pregnancy to test for the presence of Group B streptococcal infection.
has db xref: NCIT:C92805

Axiom
annotated source: prenatal group B streptococcus screening
annotated property: hasExactSynonym
annotated target: GBS
has synonym type: OMO_0003000

nuchal translucency screening
type: Class
subclass of: ultrasonography procedure
subclass of: prenatal examination
IAO_0000115: An ultrasonic examination of the fetus in the late first trimester to measure the clear space at the back of the fetal neck to assess risk of genetic or cardiac abnormalities.
date: 2020-03-19T21:03:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92837
has exact synonym: NT testing
has exact synonym: nuchal translucency ultrasound screening
has exact synonym: ultrasonographic nuchal translucency exam

Axiom
annotated source: nuchal translucency screening
annotated property: IAO_0000115
annotated target: An ultrasonic examination of the fetus in the late first trimester to measure the clear space at the back of the fetal neck to assess risk of genetic or cardiac abnormalities.
has db xref: NCIT:C92837

Axiom
annotated source: nuchal translucency screening
annotated property: hasExactSynonym
annotated target: NT testing
has synonym type: OMO_0003000

quad test assessment
type: Class
subclass of: prenatal examination
IAO_0000115: A screening measurement in which the maternal blood levels of alpha-fetoprotein, unconjugated estriol, human chorionic gonadotrophin and Inhibin A are calculated. These are then evaluated in relation to the mother's age, weight and fetal gestational age.
date: 2020-03-19T21:11:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92865
has exact synonym: quad screen
has exact synonym: quadruple marker testing

Axiom
annotated source: quad test assessment
annotated property: IAO_0000115
annotated target: A screening measurement in which the maternal blood levels of alpha-fetoprotein, unconjugated estriol, human chorionic gonadotrophin and Inhibin A are calculated. These are then evaluated in relation to the mother's age, weight and fetal gestational age.
has db xref: NCIT:C92865

eosinophil count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000771
subclass of: granulocyte count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000771
IAO_0000115: A determination of the number of eosinophil in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C64550
has exact synonym: EOS cell count
has exact synonym: eosinophil count test

Axiom
annotated source: eosinophil count
annotated property: hasExactSynonym
annotated target: EOS cell count
has synonym type: OMO_0003000

granulocyte count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000094
subclass of: leukocyte count
subclass of: MAXO_0001509
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000094
IAO_0000115: A determination of the number of granulocyte in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C96654
has exact synonym: granulocyte count test
has exact synonym: polymorphonuclear leukocyte count

basophil count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000767
subclass of: granulocyte count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000767
IAO_0000115: A determination of the number of basophil in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C64470
has exact synonym: basophil cell count
has exact synonym: basophil count test
has exact synonym: total basophil count

lymphocyte count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000542
subclass of: leukocyte count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000542
IAO_0000115: A determination of the number of lymphocyte in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C51949
has exact synonym: lymphocyte count test

clinical biospecimen collection
type: Class
subclass of: diagnostic procedure
IAO_0000115: A procedure by which biological material is obtained from a subject for testing, diagnostic, treatment, or research purposes.
date: 2020-03-27T15:53:08Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C70700
has exact synonym: clinical specimen collection

obsolete swab-based biospecimen collection
type: Class
IAO_0100001: OBI_0002600
deprecated: true

self body temperature measurement
type: Class
subclass of: body temperature measurement
IAO_0000115: Measuring a person's own body temperature usually at home using any of a number of types of thermometers.
date: 2020-03-29T18:25:39Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: self-reported temperature measurement
has narrow synonym: at home temperature measurement
has narrow synonym: self-reported fever measurement

inflammatory biomarker assessment
type: Class
subclass of: biomarker analysis
IAO_0000115: A characteristic that can be objectively measured and serves as an indicator for the inflammatory response. It could be used to indicate the normal inflammatory processes, pathogenic processes, state of health or disease, the risk for disease development and/or prognosis, or responsiveness to a particular therapeutic intervention.
date: 2020-03-29T18:32:41Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: inflammatory biomarker measurement

C-reactive protein biomarker assessment
type: Class
subclass of: inflammatory biomarker assessment
IAO_0000115: Assay based assessment of a serum sample for detection and concentration (mg/L) C-reactive protein.
date: 2020-03-29T18:33:44Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: CRP measurement
comment: C-reactive protein (CRP) measurement is a measurement of the level of C-reactive protein in the blood. Levels are known to rise in response to inflammation, CRP is therefore used as a clinical measure of inflammation. The measurement is used in the process of clinical diagnosis as high levels of CRP are associated with cardiovascular disease, diabetes and hypertension and in some cancers.

Axiom
annotated source: C-reactive protein biomarker assessment
annotated property: IAO_0000115
annotated target: Assay based assessment of a serum sample for detection and concentration (mg/L) C-reactive protein.
has db xref: PMID:11238291

Axiom
annotated source: C-reactive protein biomarker assessment
annotated property: hasExactSynonym
annotated target: CRP measurement
has synonym type: OMO_0003000

Axiom
annotated source: C-reactive protein biomarker assessment
annotated property: comment
annotated target: C-reactive protein (CRP) measurement is a measurement of the level of C-reactive protein in the blood. Levels are known to rise in response to inflammation, CRP is therefore used as a clinical measure of inflammation. The measurement is used in the process of clinical diagnosis as high levels of CRP are associated with cardiovascular disease, diabetes and hypertension and in some cancers.
has db xref: EFO:0004458

interleukin-6 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of circultating interleukin-6, which stimulates the inflammatory and auto-immune processes in many diseases.
date: 2020-03-29T18:44:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-6 level assessment
has exact synonym: IL-6 measurement
comment: A quantification of interleukin-6, a pro-inflammatory and anti-inflammatory cytokine.

Axiom
annotated source: interleukin-6 biomarker measurement
annotated property: hasExactSynonym
annotated target: IL-6 level assessment
has synonym type: OMO_0003000

Axiom
annotated source: interleukin-6 biomarker measurement
annotated property: hasExactSynonym
annotated target: IL-6 measurement
has synonym type: OMO_0003000

Axiom
annotated source: interleukin-6 biomarker measurement
annotated property: comment
annotated target: A quantification of interleukin-6, a pro-inflammatory and anti-inflammatory cytokine.
has db xref: EFO:0004810

cytokine biomarker assessment
type: Class
subclass of: inflammatory biomarker assessment
IAO_0000115: A chemokine that can be objectively measured and serves as an indicator for the inflammatory response.
date: 2020-03-30T15:51:58Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: cytokine biomarker measurement
comment: Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.
comment: Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities.

Axiom
annotated source: cytokine biomarker assessment
annotated property: comment
annotated target: Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.
has db xref: PMID:28487810

Axiom
annotated source: cytokine biomarker assessment
annotated property: comment
annotated target: Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities.
has db xref: PMID:24962838

interleukin-1 beta biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-1 beta levels, an IL-1 cytokine family protein, secreted by macrophages and a mediator of inflammatory response.
date: 2020-03-30T16:03:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-1 beta assessment

interleukin-1 alpha biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-1 alpha, a mediator of the inflammatory response.
date: 2020-03-30T16:05:46Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-1 alpha assessment
has exact synonym: IL-1 alpha testing

interleukin-2 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-2, a mediator of inflammatory response.
date: 2020-03-30T16:08:32Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-2 level assessment
has exact synonym: IL-2 testing

interleukin-8 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-8 levels, a mediator of inflammatory response.
date: 2020-03-30T16:09:36Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-8 level assessment
has exact synonym: IL-8 testing

interleukin-12 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-12 levels, an inflammatory cytokine.
date: 2020-03-30T16:24:01Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-12 assessment
has exact synonym: IL-12 level testing

tumor necrosis factor-alpha biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of TNF-alpha levels, a cytokine involved in systemic inflammation.
date: 2020-03-30T16:28:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: TNF-alpha assessment
has exact synonym: TNF-alpha level testing

interferon-gamma biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interferon-gamma, a cytokine that indicates an inflammatory response.
date: 2020-03-30T16:31:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: INF-gamma assessment
has exact synonym: INF-gamma levels testing

interleukin-4 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-4, a cytokine identified as an inflammation suppressant.
date: 2020-03-30T18:59:24Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-4 measurement
has exact synonym: IL-4 testing
has exact synonym: IL4 assessment

interleukin-5 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-5, a cytokine identified as an inflammation suppressant.
date: 2020-03-30T19:04:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-5 measurement
has exact synonym: IL-5 testing
has exact synonym: IL5 assessment

Interleukin-10 biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of interleukin-10, a cytokine identified as an inflammation suppressant.
date: 2020-03-30T19:05:58Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IL-10 measurement
has exact synonym: IL-10 testing
has exact synonym: IL10 assessment

tumor necrosis factor-beta biomarker measurement
type: Class
subclass of: cytokine biomarker assessment
IAO_0000115: Detection of tumor necrosis factor-beta (TNF-beta), a cytokine identified as an inflammation suppressant.
date: 2020-03-30T19:07:19Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: TNF-beta measurement
has exact synonym: TNF-beta testing
has exact synonym: TNFbeta assessment

serum amyloid A biomarker assessment
type: Class
subclass of: inflammatory biomarker assessment
IAO_0000115: Detection of serum levels of amyloid A (SAA) in response to inflammation.
date: 2020-03-30T19:37:28Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: SAA biomarker measurement

clinical chemistry assessment
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: A clinical laboratory procedure designed for the quantification of an organic or inorganic chemical within a biological specimen required for diagnostics or monitoring of treatments.
date: 2020-03-30T19:49:21Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49237
has exact synonym: clincal chemistry test
has exact synonym: clinical chemistry measurement testing
has exact synonym: clinical chemistry testing

blood glucose assessment
type: Class
subclass of: blood chemistry measurement
IAO_0000115: A quantitative measurement for assessing the amount of glucose present in a blood sample.
date: 2020-03-30T19:58:59Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92744
has exact synonym: blood glucose measurement
has exact synonym: blood glucose testing
has exact synonym: blood surgar testing

Axiom
annotated source: blood glucose assessment
annotated property: IAO_0000115
annotated target: A quantitative measurement for assessing the amount of glucose present in a blood sample.
has db xref: NCIT:C92744

plasma glucose assessment
type: Class
subclass of: blood glucose assessment
IAO_0000115: Glucose Plasma Concentration (GPC) measurement is an essential diagnostic modality for different types of carbohydrate metabolism derangements including diabetes mellitus.
date: 2020-03-30T20:02:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C41376
has exact synonym: plasma glucose measurement
comment: Glucose Plasma Concentration (GPC) measurement is an essential diagnostic modality for different types of carbohydrate metabolism derangements including diabetes mellitus. The disordered carbohydrate metabolism that underlies diabetes manifests as hyperglycemia. Plasma glucose concentrations in healthy individuals vary with age. Normal fasting plasma glucose intervals (in the morning after an overnight fast) in children are 3.3 - 5.6 mmol/L (60-100 mg/dL); adult range - 4.1- 5.9 mmol/L (74-106 mg/dL). GPCs are approximately 11% higher than whole blood if the hematocrit is normal. Glucose concentrations in heparinized plasma are reported to be 5% lower than in serum.

Axiom
annotated source: plasma glucose assessment
annotated property: comment
annotated target: Glucose Plasma Concentration (GPC) measurement is an essential diagnostic modality for different types of carbohydrate metabolism derangements including diabetes mellitus. The disordered carbohydrate metabolism that underlies diabetes manifests as hyperglycemia. Plasma glucose concentrations in healthy individuals vary with age. Normal fasting plasma glucose intervals (in the morning after an overnight fast) in children are 3.3 - 5.6 mmol/L (60-100 mg/dL); adult range - 4.1- 5.9 mmol/L (74-106 mg/dL). GPCs are approximately 11% higher than whole blood if the hematocrit is normal. Glucose concentrations in heparinized plasma are reported to be 5% lower than in serum.
has db xref: NCIT:C41376

fasting blood glucose assessment
type: Class
subclass of: blood glucose assessment
IAO_0000115: A quantitative measurement of the amount of glucose present in a sample of blood, obtained from a source that has abstained from nutrition, typically at least 8 hours prior to the sample collection time.
date: 2020-03-30T20:05:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C80400
has exact synonym: FBS measurement
has exact synonym: fasting blood glucose measurement
has exact synonym: fasting blood sugar measurement testing

Axiom
annotated source: fasting blood glucose assessment
annotated property: IAO_0000115
annotated target: A quantitative measurement of the amount of glucose present in a sample of blood, obtained from a source that has abstained from nutrition, typically at least 8 hours prior to the sample collection time.
has db xref: NCIT:C80400

induced sputum collection
type: Class
subclass of: sputum specimen collection
IAO_0000115: A technique to collect sputum by inhaling hypertonic saline through an oxygen mask in order to induce sputum.
date: 2020-03-30T20:17:26Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: induced sputum collection
annotated property: IAO_0000115
annotated target: A technique to collect sputum by inhaling hypertonic saline through an oxygen mask in order to induce sputum.
has db xref: PMID:32171389

computed tomography procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: A method of examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis.
date: 2020-03-30T20:32:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17204
has exact synonym: CAT scan
has exact synonym: CT
has exact synonym: CT scan
has exact synonym: computerized axial tomography

Axiom
annotated source: computed tomography procedure
annotated property: IAO_0000115
annotated target: A method of examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis.
has db xref: NCIT:C17204

hypoglycemic drug therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35526
subclass of: antidiabetic agent therapy
subclass of: glycemic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35526
IAO_0000115: Use of a drug that lower the level of glucose in the blood.
date: 2020-03-31T00:42:37Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35526
has exact synonym: hypoglycaemic drug therapy
has exact synonym: treatment with hypoglycemic agent
has exact synonym: treatment with hypoglycemic drug
has exact synonym: treatment with hypoglycemic medication

antiretroviral therapy
type: Class
subclass of: antiviral agent therapy
IAO_0000115: Treatment of retroviral infections with medications that target the virus directly, limiting the ability of infected cells to produce new virus particles.
date: 2020-03-31T00:49:23Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C94631
has exact synonym: ART
has exact synonym: anti-retroviral therapy
has exact synonym: treatment with an anti-retroviral medication
has exact synonym: treatment with an antiretroviral drug
has exact synonym: treatment with an antiretroviral medication

Axiom
annotated source: antiretroviral therapy
annotated property: IAO_0000115
annotated target: Treatment of retroviral infections with medications that target the virus directly, limiting the ability of infected cells to produce new virus particles.
has db xref: NCIT:C94631

medical history taking
type: Class
subclass of: examination by clinical professional
IAO_0000115: The process of gathering information regarding a person's medical history.
date: 2020-03-31T00:59:49Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: patient assessment
has db xref: NCIT:C146918
has exact synonym: medical history collection

Axiom
annotated source: medical history taking
annotated property: IAO_0000115
annotated target: The process of gathering information regarding a person's medical history.
has db xref: NCIT:C146918

patient demographic characteristics assessment
type: Class
subclass of: medical history taking
IAO_0000115: Determination if a patient's background or demographic characteristics makes the patient susceptible to disease.
date: 2020-03-31T01:03:49Z
creator: http://orcid.org/0000-0001-7941-2961

patient travel risk assessment
type: Class
subclass of: medical history taking
subclass of: infectious disease screening
IAO_0000115: Determination if patient's travel history may impact current health.
date: 2020-03-31T01:05:10Z
creator: http://orcid.org/0000-0001-7941-2961

patient travel risk questionnaire
type: Class
subclass of: patient travel risk assessment
IAO_0000115: A questionnaire designed to determine if patient's travel history may impact current health.
date: 2020-03-31T01:05:32Z
creator: http://orcid.org/0000-0001-7941-2961

patient environmental exposure assessment
type: Class
subclass of: medical history taking
IAO_0000115: Determination if the patient may have been exposed to something which would impact the health of the patient.
date: 2020-03-31T01:11:38Z
creator: http://orcid.org/0000-0001-7941-2961

blood gas assessment
type: Class
subclass of: blood chemistry measurement
IAO_0000115: A test that measures the amount of oxygen and carbon dioxide in the blood. It may also be used to determine the pH of the blood.
date: 2020-03-31T19:11:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C71252
has exact synonym: blood gas measurement testing
has exact synonym: blood gas test
has narrow synonym: arterial blood gas measurement
comment: pH and blood gas measurements are used to detect and monitor ventilation, oxygenation, and acid-base disturbances.

Axiom
annotated source: blood gas assessment
annotated property: comment
annotated target: pH and blood gas measurements are used to detect and monitor ventilation, oxygenation, and acid-base disturbances.
has db xref: PMID:33371

anion gap assessment
type: Class
subclass of: blood chemistry measurement
IAO_0000115: The determination of the unmeasured anions (those other than the chloride and bicarbonate anions) present in a sample.
date: 2020-03-31T19:16:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74685
has exact synonym: anion gap measurement testing

Axiom
annotated source: anion gap assessment
annotated property: IAO_0000115
annotated target: The determination of the unmeasured anions (those other than the chloride and bicarbonate anions) present in a sample.
has db xref: NCIT:C74685

calcium assessment
type: Class
subclass of: clinical chemistry assessment
IAO_0000115: A quantitative measurement of the amount of calcium present in a sample, usually serum or urine.
date: 2020-03-31T19:19:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64488
has exact synonym: calcium measurement

electrolyte assessment
type: Class
subclass of: clinical chemistry assessment
IAO_0000115: A quantitative measurement of the amount of an electrolyte present in urine or serum.
date: 2020-03-31T19:32:42Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74946
has exact synonym: electrolyte measurement

serum electrolyte assessment
type: Class
subclass of: electrolyte assessment
subclass of: serum chemistry measurement
IAO_0000115: A quantitative measurement of the amount of an electrolyte present in serum.
date: 2020-03-31T19:33:45Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: electrolytes- serum testing
has exact synonym: serum electrolyte measurement

urine eletrolyte assessment
type: Class
subclass of: electrolyte assessment
subclass of: urine chemistry measurement
IAO_0000115: A quantitative measurement of the amount of an electrolyte present in urine.
date: 2020-03-31T19:34:22Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: electrolytes- urine testing
has exact synonym: urine eletrolyte measurement

microbial culture procedure
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: Any laboratory procedure for growing microorganisms.
date: 2020-03-31T20:08:52Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C25300

Axiom
annotated source: microbial culture procedure
annotated property: IAO_0000115
annotated target: Any laboratory procedure for growing microorganisms.
has db xref: NCIT:C25300

invasive ventilation
type: Class
subclass of: artificial respiration
IAO_0000115: A type of mechanical ventilation using endotracheal intubation.
date: 2020-03-31T20:23:41Z
creator: http://orcid.org/0000-0001-7941-2961

airway pressure release ventilation
type: Class
subclass of: artificial respiration
IAO_0000115: A time-triggered, pressure-limited, inverse-ratio mode of ventilation that provides continuous distending airway pressure with intermittent release phases
date: 2020-04-01T20:00:59Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: APRV

Axiom
annotated source: airway pressure release ventilation
annotated property: IAO_0000115
annotated target: A time-triggered, pressure-limited, inverse-ratio mode of ventilation that provides continuous distending airway pressure with intermittent release phases
has db xref: PMID:29641221

Axiom
annotated source: airway pressure release ventilation
annotated property: hasExactSynonym
annotated target: APRV
has synonym type: OMO_0003000

clinical nucleic acid testing for pathogens
type: Class
subclass of: clinical laboratory procedure
IAO_0000115: A technique that detects a particular nucleic acid sequence in order to identify a pathogen (organism or virus) in blood, tissue, urine, or other bodily fluids.
date: 2020-04-02T20:59:07Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: NAT
has exact synonym: clinical nucleic acid testing
has exact synonym: nucleic acid testing
has exact synonym: pathogen nucleic acid testing

Axiom
annotated source: clinical nucleic acid testing for pathogens
annotated property: hasExactSynonym
annotated target: NAT
has synonym type: OMO_0003000

nucleic acid amplification testing
type: Class
subclass of: clinical nucleic acid testing for pathogens
IAO_0000115: A tecnique that uses an amplification of nucleic acids to detect a pathogen. Some amplification methods include polymerase chain reaction (PCR), strand displacement assay (SDA), or transcription mediated assay (TMA) to detect a virus, bacteria or other pathogen.
date: 2020-04-02T21:17:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C20055
has exact synonym: NAAT
has exact synonym: nucleic acid amplification procedure
comment: Any of various amplification and detection strategies applied to detection of virus contamination in donor blood. Specifically designed to detect recently infected individuals during the latency period before seroconversion.

Axiom
annotated source: nucleic acid amplification testing
annotated property: hasExactSynonym
annotated target: NAAT
has synonym type: OMO_0003000

Axiom
annotated source: nucleic acid amplification testing
annotated property: comment
annotated target: Any of various amplification and detection strategies applied to detection of virus contamination in donor blood. Specifically designed to detect recently infected individuals during the latency period before seroconversion.
has db xref: NCIT:C20055

loop-mediated isothermal amplification testing
type: Class
subclass of: nucleic acid amplification testing
IAO_0000115: A type of nucleic acid amplification test in which sample DNA is exposed to a single temperature in the presence of multiple sets of primers and a polymerase with replication and high strand displacement activity. This test negates the need for thermal cyclers and may be a low cost alternative to PCR.
date: 2020-04-02T21:43:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C102661
has exact synonym: loop-mediated isothermal amplification procedure

Axiom
annotated source: loop-mediated isothermal amplification testing
annotated property: IAO_0000115
annotated target: A type of nucleic acid amplification test in which sample DNA is exposed to a single temperature in the presence of multiple sets of primers and a polymerase with replication and high strand displacement activity. This test negates the need for thermal cyclers and may be a low cost alternative to PCR.
has db xref: NCIT:C102661

clinical DNA detection testing
type: Class
subclass of: clinical nucleic acid testing for pathogens
IAO_0000115: A technique that detects a particular DNA sequence in order to identify a pathogen (organism or virus) in blood, tissue, urine, or other bodily fluids.
date: 2020-04-03T00:29:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: DNA detection examination
has exact synonym: DNA detection procedure
has exact synonym: DNA detection testing
has narrow synonym: DNA detection kit testing

clinical RNA detection testing
type: Class
subclass of: clinical nucleic acid testing for pathogens
IAO_0000115: A technique that detects a particular RNA sequence in order to identify a pathogen (organism or virus) in blood, tissue, urine, or other bodily fluids.
date: 2020-04-03T00:30:09Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: RNA detection examination
has exact synonym: RNA detection procedure
has exact synonym: RNA detection testing
has narrow synonym: RNA detection kit testing

clinical real-time PCR testing
type: Class
subclass of: nucleic acid amplification testing
IAO_0000115: A clinical assay that amplifies and quantifies a specific DNA molecule based on in tissue, blood, sputum, urine, or any other bodily fluid to detect the presence of a pathogen. It enables both detection and quantification of one or more specific sequences in a DNA sample.
date: 2020-04-03T00:38:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51962
has db xref: OBI:0000893
has exact synonym: clinical qPCR testing
has exact synonym: clinical real-time RT-PCR procedure
has exact synonym: real-time PCR procedure for clinical use

clinical quantitative reverse transcription PCR testing
type: Class
subclass of: nucleic acid amplification testing
IAO_0000115: A method to measure very small amounts of RNA transcripts as cDNA targets from tissue, blood, sputum or other body fluids.
date: 2020-04-03T00:47:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C28408
has db xref: OBI:0000911
has exact synonym: clinical quantitative RT-PCR procedure
has exact synonym: clinical quantitative RT-PCR testing
has exact synonym: clinical quantitative reverse transcription PCR procedure

radiograph imaging procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: A procedure producing an image on a radiosensitive surface by x-ray radiation that has penetrated and passed through a structure in order to diagnose or treat a patient.
date: 2020-04-07T15:49:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38101
has db xref: NCIT:C60727
has exact synonym: X-ray imaging procedure
has exact synonym: radiogram imaging procedure
has exact synonym: radiographic imaging procedure
has exact synonym: radiographic procedure
has exact synonym: radiography
has exact synonym: radiography imaging procedure

infectious disease screening
type: Class
subclass of: disease screening
IAO_0000115: The process of taking a thorough history and physical exam to determine if a patient has been exposed to an infectious disease. Close attention is paid to travel history, environmental exposures, and vaccination history.
date: 2020-04-07T18:27:36Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: infectious disease testing

supplemental oxygen therapy with mask
type: Class
subclass of: supplemental oxygen therapy
IAO_0000115: The administration of oxygen to an individual, usually to aid in respiration by means of a mask.
date: 2020-04-07T19:00:52Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: oxygen support therapy with mask

supplemental oxygen therapy with nasal cannula
type: Class
subclass of: supplemental oxygen therapy
IAO_0000115: The administration of oxygen to an individual, usually to aid in respiration by means of a nasal cannula.
date: 2020-04-07T19:01:10Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: oxygen support therapy with nasal cannula

vasopressor agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_137431
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_137431
IAO_0000115: Therapy using a substance used in the treatment of hypotension. A vasopressor agent increases reduced blood pressure.
date: 2020-04-07T19:23:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:137431
has db xref: NCIT:C126567
has exact synonym: antihypotensive agent drug therapy
has exact synonym: treatment with antihypotensive agent
has exact synonym: treatment with antihypotensive drug
has exact synonym: treatment with antihypotensive medication
has exact synonym: treatment with vasopressor agent
has exact synonym: treatment with vasopressor medication
has exact synonym: vasopressor support therapy

renal replacement therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: Treatments that substitute for the blood-filtering function of the kidneys.
date: 2020-04-07T19:42:23Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: MeSH:D017582
has db xref: NCIT:C126400
has exact synonym: RRT
has exact synonym: kidney replacement therapy
comment: It includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration. Kidney transplant may also be considered a renal replacement therapy.

Axiom
annotated source: renal replacement therapy
annotated property: hasExactSynonym
annotated target: RRT
has synonym type: OMO_0003000

renal dialysis
type: Class
subclass of: renal replacement therapy
IAO_0000115: A procedure to remove toxic substances from the blood that is used in patients with end-stage chronic kidney disease or acute kidney failure. This includes hemodialysis and peritoneal dialysis.
date: 2020-04-07T19:57:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15221
has exact synonym: dialysis

hemodialysis
type: Class
subclass of: renal dialysis
IAO_0000115: A therapeutic procedure used in patients with kidney failure. It involves the extracorporeal removal of harmful wastes and fluids from the blood using a dialysis machine. Following the dialysis, the blood is returned to the body.
date: 2020-04-07T20:03:50Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15248

Axiom
annotated source: hemodialysis
annotated property: IAO_0000115
annotated target: A therapeutic procedure used in patients with kidney failure. It involves the extracorporeal removal of harmful wastes and fluids from the blood using a dialysis machine. Following the dialysis, the blood is returned to the body.
has db xref: NCIT:C15248

peritoneal dialysis
type: Class
subclass of: renal dialysis
IAO_0000115: A form of dialysis that uses the peritoneum as a membrane across which the infused diasylate exchanges nutrients for waste products that are removed when the fluid is exchanged.
date: 2020-04-07T20:04:03Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15297

Axiom
annotated source: peritoneal dialysis
annotated property: IAO_0000115
annotated target: A form of dialysis that uses the peritoneum as a membrane across which the infused diasylate exchanges nutrients for waste products that are removed when the fluid is exchanged.
has db xref: NCIT:C15297

endocrine testing
type: Class
subclass of: clinical chemistry assessment
IAO_0000115: A laboratory procedure that tests the function of an endocrine organ and measures the amount of a hormone present in a sample.
date: 2020-04-07T20:40:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74971

Axiom
annotated source: endocrine testing
annotated property: IAO_0000115
annotated target: A laboratory procedure that tests the function of an endocrine organ and measures the amount of a hormone present in a sample.
has db xref: NCIT:C74971

protein measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000000001
subclass of: clinical chemistry assessment
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000000001
IAO_0000115: The determination of the amount of protein present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-04-07T20:51:38Z
has db xref: NCIT:C64430
has exact synonym: protein assessment
has exact synonym: protein test

procalcitonin assessment
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000050338
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000050338
IAO_0000115: The determination of the amount of procalcitonin (human) present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-04-07T21:30:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C103430
has exact synonym: procalcitonin (human) assessment
has exact synonym: procalcitonin (human) test
has exact synonym: procalcitonin level measurement
has exact synonym: procalcitonin level testing
has exact synonym: procalcitonin testing
comment: A substance produced in response to bacterial infections and tissue injury.

D-dimer assessment
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000050369
subclass of: clinical chemistry assessment
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000050369
IAO_0000115: The determination of the amount of D-dimer (human) present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-04-07T21:37:45Z
has db xref: NCIT:C82621
has exact synonym: D dimer level testing
has exact synonym: D-dimer (human) assessment
has exact synonym: D-dimer (human) test
has exact synonym: D-dimer measurement
has exact synonym: fibrin degradation fragment testing
has exact synonym: fragment D-dimer testing
comment: A quantification of a fibrin degradation product in blood used in the diagnosis of thrombosis.

serum phosphate assessment
type: Class
subclass of: serum electrolyte assessment
IAO_0000115: A quantitative measurement of the amount of phosphate present in a sample of serum.
date: 2020-04-07T21:53:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C61028
has exact synonym: serum phosphate measurement
has exact synonym: serum phosphorus measurement

Axiom
annotated source: serum phosphate assessment
annotated property: IAO_0000115
annotated target: A quantitative measurement of the amount of phosphate present in a sample of serum.
has db xref: NCIT:C61028

serology testing
type: Class
subclass of: hematology testing
IAO_0000115: Testing blood serum for the presence of specifc antibody or antibodies to a specific antigen. Often used when an infection is suspected.
date: 2020-04-08T14:34:24Z
creator: http://orcid.org/0000-0001-7941-2961
has related synonym: serology assay

clinical ELISA testing
type: Class
subclass of: clinical immunoassay
IAO_0000115: A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)
date: 2020-04-08T14:51:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C16553
has db xref: OBI:0000661
has exact synonym: enzyme linked immunosorbent assay testing
has exact synonym: enzyme-linked immunosorbent assay

Axiom
annotated source: clinical ELISA testing
annotated property: IAO_0000115
annotated target: A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)
has db xref: NCIT:C16553

rapid IgM-IgG combined antibody testing
type: Class
subclass of: clinical lateral flow assay testing
IAO_0000115: A type of lateral flow assay that qualitatively detect IgG and IgM antibodies of an infectious disease within human serum, plasma or whole blood in vitro.
date: 2020-04-08T15:03:41Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: rapid IgM-IgG testing

clinical lateral flow assay testing
type: Class
subclass of: clinical immunoassay
IAO_0000115: A procedure using a paper-based platform for the detection and quantification of analytes in complex mixtures, where the sample is placed on a test device for clinical use.
date: 2020-04-08T15:06:47Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: LFA testing
has exact synonym: lateral flow immuno assay
has exact synonym: lateral flow immunoassay

Axiom
annotated source: clinical lateral flow assay testing
annotated property: IAO_0000115
annotated target: A procedure using a paper-based platform for the detection and quantification of analytes in complex mixtures, where the sample is placed on a test device for clinical use.
has db xref: PMID:27365041

Axiom
annotated source: clinical lateral flow assay testing
annotated property: hasExactSynonym
annotated target: LFA testing
has synonym type: OMO_0003000

clinical immunoassay
type: Class
subclass of: serology testing
IAO_0000115: Any of several immunoassay methods that use an enzyme covalently linked to an antigen or antibody as a label and are typically used for diagnostics or disease progression.
date: 2020-04-08T15:17:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17455

clinical immunofluorescence assay testing
type: Class
subclass of: clinical immunoassay
IAO_0000115: Immunofluorescence staining used in a pathology or clinical lab to diagnose diseases of the skin, kidney, heart, cilia and other organ systems.
date: 2020-04-08T15:46:23Z
creator: http://orcid.org/0000-0001-7941-2961

clinical immunoblot assay testing
type: Class
subclass of: clinical immunoassay
IAO_0000115: A technique for analyzing or identifying proteins immobilized on a filter by complementary reaction with specific antibodies.
date: 2020-04-08T15:46:38Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17638
has db xref: OBI:0001978
has exact synonym: clinical Western blot assay

Axiom
annotated source: clinical immunoblot assay testing
annotated property: IAO_0000115
annotated target: A technique for analyzing or identifying proteins immobilized on a filter by complementary reaction with specific antibodies.
has db xref: NCIT:C17638

oxygen saturation measurement
type: Class
subclass of: clinical assessment
IAO_0000115: The measurement of the ratio of oxygenated hemoglobin to total hemoglobin in the blood.
date: 2020-04-08T18:45:55Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C60832

Axiom
annotated source: oxygen saturation measurement
annotated property: IAO_0000115
annotated target: The measurement of the ratio of oxygenated hemoglobin to total hemoglobin in the blood.
has db xref: NCIT:C60832

pulse oximetry
type: Class
subclass of: oxygen saturation measurement
IAO_0000115: A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin.
date: 2020-04-08T18:54:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38085
has exact synonym: pulse ox measurement

Axiom
annotated source: pulse oximetry
annotated property: IAO_0000115
annotated target: A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin.
has db xref: NCIT:C38085

fluid replacement therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: A therapy of replenishing bodily fluids lost through sweating, bleeding, fluid shifts or other pathological processes, such as sepsis.
date: 2020-04-08T19:29:53Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: fluid resuscitation therapy

ventilation with proning
type: Class
subclass of: artificial respiration
IAO_0000115: Prone positioning improves ventilation-perfusion matching (transferring delivered oxygen into the bloodstream more efficiently) and keeps alveolar units open and evenly distributed at end-expiration (improving gas exchange and preventing ventilator-induced lung injury).
date: 2020-04-08T19:45:40Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: ventilation with proning
annotated property: IAO_0000115
annotated target: Prone positioning improves ventilation-perfusion matching (transferring delivered oxygen into the bloodstream more efficiently) and keeps alveolar units open and evenly distributed at end-expiration (improving gas exchange and preventing ventilator-induced lung injury).
has db xref: prone-positioning-ards-ats-sccm

central venous cannula insertion
type: Class
subclass of: medical device implantation
IAO_0000115: A procedure of surgical placement of a catheter, which lumen is usually occupied by a trocar, into the central vein (internal jugular, subclavian, and femoral often used) or veins, to provide vascular access for measurement of hemodynamic variables that cannot be measured accurately by noninvasive means. It also can be used to deliver medications that were too potent or too toxic to be administered through peripheral access, for parenteral nutrition delivery; and for placing wires and pulmonary artery catheters. Central veins are usually cannulated percutaneously. The procedure is associated with many adverse events and has to be performed or supervised by an experienced physician.
date: 2020-04-08T20:12:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C40972
has exact synonym: central line insertion
has exact synonym: central line placement
has exact synonym: central venous access catheter insertion
has exact synonym: central venous line insertion
has exact synonym: cvc insertion

Axiom
annotated source: central venous cannula insertion
annotated property: IAO_0000115
annotated target: A procedure of surgical placement of a catheter, which lumen is usually occupied by a trocar, into the central vein (internal jugular, subclavian, and femoral often used) or veins, to provide vascular access for measurement of hemodynamic variables that cannot be measured accurately by noninvasive means. It also can be used to deliver medications that were too potent or too toxic to be administered through peripheral access, for parenteral nutrition delivery; and for placing wires and pulmonary artery catheters. Central veins are usually cannulated percutaneously. The procedure is associated with many adverse events and has to be performed or supervised by an experienced physician.
has db xref: NCIT:C40972

arterial catheter line insertion
type: Class
subclass of: MAXO_0009033
IAO_0000115: A thin catheter inserted into an artery to monitor blood pressure directly and obtain blood samples.
date: 2020-04-08T20:20:40Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: a-line insertion
has exact synonym: art-line placement
has exact synonym: arterial line placement

noninvasive positve-pressure ventilation
type: Class
subclass of: noninvasive ventilation
subclass of: positive controlled ventilation
IAO_0000115: Allows delivery of positive-pressure ventilation with a tight-fitting nasal or facial mask that is attached to a continuous positive airway pressure (CPAP) or a bilevel positive airway pressure (BiPAP) machine.
date: 2020-04-27T20:57:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: NIPPV
has exact synonym: non-invasive positive pressure ventilation

Axiom
annotated source: noninvasive positve-pressure ventilation
annotated property: hasExactSynonym
annotated target: NIPPV
has synonym type: OMO_0003000

nutrition counseling
type: Class
subclass of: behavioral counseling
IAO_0000115: Nutrition intervention for nutrition counseling is a supportive process, characterized by a collaborative counselor–patient/client relationship to establish food, nutrition and physical activity priorities, goals, and individualized action plans that acknowledge and foster responsibility for self-care to treat an existing condition and promote health.
date: 2020-04-28T16:03:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: https://orcid.org/0000-0002-7463-6306
has exact synonym: dietary counseling
has exact synonym: nutritional counseling

Axiom
annotated source: nutrition counseling
annotated property: IAO_0000115
annotated target: Nutrition intervention for nutrition counseling is a supportive process, characterized by a collaborative counselor–patient/client relationship to establish food, nutrition and physical activity priorities, goals, and individualized action plans that acknowledge and foster responsibility for self-care to treat an existing condition and promote health.
comment: Reference: Academy of Nutrition and Dietetics. Nutrition Terminology Reference Manual (eNCPT): Dietetics Language for Nutrition Care 2014, Nutrition Intervention/Terms and Definitions/Nutrition Counseling (C), page-064, http://ncpt.webauthor.com

nutrition assessment
type: Class
subclass of: nutrition counseling
IAO_0000115: An in-depth evaluation of an individual's food and nutrient intake, lifestyle, and medical history designed to help the individual either maintain their health status or attain a healthier status.
date: 2020-04-28T16:12:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: https://orcid.org/0000-0002-7463-6306
has db xref: NCIT:C15286
has exact synonym: dietary assessment
has exact synonym: nutritional assessment

Axiom
annotated source: nutrition assessment
annotated property: IAO_0000115
annotated target: An in-depth evaluation of an individual's food and nutrient intake, lifestyle, and medical history designed to help the individual either maintain their health status or attain a healthier status.
has db xref: NCIT:C15286

inhalation anesthetic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38870
subclass of: general anesthetic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38870
IAO_0000115: A therapy utilizing an inhaled substance that produces loss of consciousness.
date: 2020-05-26T16:13:05Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: anesthetic gas therapy
has exact synonym: gas anesthetic drug therapy
has exact synonym: inhalation anaesthetic drug therapy
has exact synonym: inhalation anaesthetic medication therapy
has exact synonym: inhalation anesthesia treatment
has exact synonym: inhalation anesthetic drug therapy
has exact synonym: inhalation anesthetic medication therapy
has exact synonym: inhalation anesthetic treatment
has exact synonym: inhalation anesthetic utilization
has exact synonym: treatment with inhalation anaesthetic

intravenous anesthetic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38877
subclass of: general anesthetic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38877
IAO_0000115: A therapy utilizing an intravenous substance that produces loss of consciousness.
date: 2020-05-26T18:19:32Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: IV anaesthetic agent therapy
has exact synonym: IV anesthetic agent therapy
has exact synonym: i.v. anesthetic agent therapy
has exact synonym: i.v. anesthetic drug therapy
has exact synonym: i.v. anesthetic drug treatment
has exact synonym: i.v. anesthetic medication therapy
has exact synonym: intravenous anaesthetic agent therapy
has exact synonym: intravenous anesthesia treatment
has exact synonym: intravenous anesthetic drug therapy
has exact synonym: intravenous anesthetic medication therapy
has exact synonym: treatment with intravenous anaesthetic

topical anesthetic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48425
subclass of: local anaesthetic agent therapy
subclass of: MAXO_0001573
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48425
IAO_0000115: Treatment with an agent that causes a superficial loss of sensation in conjunctiva, mucous membranes, or skin, produced by direct application of local anesthetic solutions, ointments, gels or sprays.
date: 2020-05-26T18:25:03Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: topical anaesthetic agent therapy
has exact synonym: topical anaesthetic drug treatment
has exact synonym: topical anesthesia treatment
has exact synonym: topical anesthetic drug therapy
has exact synonym: topical anesthetic medication treatment
has exact synonym: treatment with topical anaesthetic

Axiom
annotated source: topical anesthetic therapy
annotated property: IAO_0000115
annotated target: Treatment with an agent that causes a superficial loss of sensation in conjunctiva, mucous membranes, or skin, produced by direct application of local anesthetic solutions, ointments, gels or sprays.
has db xref: PMID:26702198

angiogenesis modulating agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50926
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50926
IAO_0000115: Use of an agent that modulates the physiologic angiogenesis process.
date: 2020-05-26T19:04:03Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50926
has exact synonym: angiogenesis modulating drug treatment
has exact synonym: angiogenesis modulating medication therapy
has exact synonym: treatment with angiogenesis modulating agent

obsolete angiogenesis inducing agent therapy
type: Class
IAO_0100001: pro-angiogenic agent therapy
deprecated: true

pro-angiogenic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_72571
subclass of: angiogenesis modulating agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_72571
IAO_0000115: Use of a compound that promotes the growth of new blood vessels from pre-existing vessels.
date: 2020-05-26T19:22:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:72571
has exact synonym: pro-angiogenic drug treatment
has exact synonym: pro-angiogenic medication therapy
has exact synonym: pro-angiogenic medication treatment
has exact synonym: proangiogenic agent therapy
has exact synonym: treatment with pro-angiogenic agent

antacid agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_65265
subclass of: gastrointestinal agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_65265
IAO_0000115: A therapy used to neutralize stomach acidity.
date: 2020-05-26T19:41:56Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:65265
has exact synonym: antacid drug therapy
has exact synonym: antacid medication therapy
has exact synonym: treatment with antacid

anti-ulcer agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_49201
subclass of: gastrointestinal agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_49201
IAO_0000115: A therapy used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
date: 2020-05-26T20:00:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:49201
has exact synonym: anti-ulcer medication treatment
has exact synonym: treatment with anti-ulcer agent
has exact synonym: treatment with anti-ulcer drug
has exact synonym: treatment with anti-ulcer medication

allergy agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50857
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50857
IAO_0000115: Treatment of allergic reactions with medications.
date: 2020-05-26T20:23:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50857
has exact synonym: allergy drug therapy
has exact synonym: allergy drug treatment
has exact synonym: allergy medication therapy
has exact synonym: anti-allergic drug therapy
has exact synonym: anti-allergic drug treatment
has exact synonym: anti-allergic medication therapy
has exact synonym: anti-allergic medication treatment
has exact synonym: treatment with allergy medication
has exact synonym: treatment with an allergy drug
has exact synonym: treatment with anti-allergic agent

anti-asthmatic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_49167
subclass of: respiratory tract agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_49167
IAO_0000115: Usage of a drug to treat asthma.
date: 2020-05-26T20:37:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:49167
has exact synonym: anti-asthma drug therapy
has exact synonym: anti-asthma drug treatment
has exact synonym: asthma medication therapy
has exact synonym: drug treatment of asthma
has exact synonym: treatment with anti-asthmatic drug

anti-estrogen agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50837
subclass of: antineoplastic therapy
subclass of: receptor antagonist therapy
subclass of: estrogen modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50837
IAO_0000115: Treatment with a drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present.
date: 2020-05-26T21:17:28Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50751
has exact synonym: anti-estrogen drug therapy
has exact synonym: anti-estrogen medication treatment
has exact synonym: anti-oestrogen agent therapy
has exact synonym: treatment with anti-estrogen agent
has exact synonym: treatment with anti-estrogen drug
has exact synonym: treatment with anti-estrogen medication
has exact synonym: treatment with anti-oestrogen medication
has exact synonym: treatment with antiestrogen medication
has exact synonym: treatment with antioestrogen medication
has exact synonym: treatment with estrogen antagonist

antidyskinesia agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_66956
subclass of: central nervous system agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_66956
IAO_0000115: Use of a compound which can be used to treat or alleviate the symptoms of dyskinesia.
date: 2020-05-27T14:13:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:66956
has exact synonym: anti-dyskinesia agent therapy
has exact synonym: anti-dyskinesia medication therapy
has exact synonym: anti-dyskinetic drug therapy
has exact synonym: anti-dyskinetic medication therapy
has exact synonym: antidyskinesia drug therapy
has exact synonym: antidyskinetic drug therapy
has exact synonym: antidyskinetic medication therapy
has exact synonym: treatment with an anti-dyskinesia drug
has exact synonym: treatment with an antidyskinetic drug
has exact synonym: treatment with anti-dyskinesia medication
has exact synonym: treatment with anti-dyskinetic drug
has exact synonym: treatment with anti-dyskinetic medication
has exact synonym: treatment with antidyskinesia agent
has exact synonym: treatment with antidyskinesia drug
has exact synonym: treatment with antidyskinesia medication
has exact synonym: treatment with antidyskinetic medication

anti-HSV agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64952
subclass of: antiherpetic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64952
IAO_0000115: Treatment with an antiviral agent that destroys or inhibits the replication of the herpes simplex virus.
date: 2020-05-28T13:49:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64952
has exact synonym: Treatment of HSV with drug
has exact synonym: Treatment of HSV with medication
has exact synonym: Treatment of herpes simplex virus with medication
has exact synonym: Treatment with anti-HSV drug
has exact synonym: Treatment with anti-HSV medication
has exact synonym: Treatment with anti-herpes simplex virus drug
has exact synonym: Treatment with anti-herpes simplex virus medication
has exact synonym: anti-HSV drug therapy
has exact synonym: anti-HSV drug treatment
has exact synonym: anti-HSV medication therapy
has exact synonym: anti-herpes simplex virus agent therapy
has exact synonym: anti-herpes simplex virus drug therapy
has exact synonym: anti-herpes simplex virus drug treatment
has exact synonym: anti-herpes simplex virus medication therapy
has exact synonym: treatment with anti-HSV agent

anti-HSV-1 agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64953
subclass of: anti-HSV agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64953
IAO_0000115: Treatment with an antiviral agent that destroys or inhibits the replication of the herpes simplex virus-1.
date: 2020-05-28T14:07:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64953
has exact synonym: anti-herpes simplex virus 1 drug therapy
has exact synonym: anti-herpes simplex virus 1 medication treatment
has exact synonym: treatment for HSV-1 with medication
has exact synonym: treatment with anti-HSV-1 agent
has exact synonym: treatment with anti-HSV-1 drug
has exact synonym: treatment with anti-HSV-1 medication

anti-HSV-2 agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64954
subclass of: anti-HSV agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64954
IAO_0000115: Treatment with an antiviral agent that destroys or inhibits the replication of the herpes simplex virus-2.
date: 2020-05-28T14:07:27Z
date: 2020-05-28T14:20:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64954
has exact synonym: anti-herpes simplex virus 2 drug therapy
has exact synonym: anti-herpes simplex virus 2 medication treatment
has exact synonym: treatment for HSV-2 with medication
has exact synonym: treatment with anti-HSV-2 agent
has exact synonym: treatment with anti-HSV-2 drug
has exact synonym: treatment with anti-HSV-2 medication

corticosteroid agent therapy
type: Class
subclass of: MAXO_0001575
IAO_0000115: Use of a natural or synthetic analog of the hormones secreted by the adrenal gland as a type of anti-inflammatory treatment.
date: 2020-05-28T15:10:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50858
has exact synonym: corticosteroid treatment
has exact synonym: treatment with corticosteroid agent
has exact synonym: treatment with corticosteroid drug
has exact synonym: treatment with corticosteroid medication
has exact synonym: treatment with corticosteroid therapy
has narrow synonym: corticosteroid injection treatment
has narrow synonym: oral corticosteroid drug treatment

emetic therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_149552
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_149552
IAO_0000115: Treatment to induce vomiting and nausea usually administered in emergency situations after ingestion of a toxin.
date: 2020-05-28T18:31:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:149552
has exact synonym: emetic drug therapy
has exact synonym: emetic medication therapy
has exact synonym: treatment with an emetic drug
has exact synonym: treatment with an emetic medication
has exact synonym: treatment with an emetic therapy
has exact synonym: treatment with emetic

antirheumatic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35842
subclass of: anti-inflammatory agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35842
IAO_0000115: Treatment with a drug to alleviate rheumatoid arthritis and its symptoms.
date: 2020-05-28T18:46:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35842
has exact synonym: anti-rheumatic agent therapy
has exact synonym: anti-rheumatic drug therapy
has exact synonym: anti-rheumatic medication therapy
has exact synonym: antirheumatic drug treatment
has exact synonym: antirheumatic medication therapy
has exact synonym: treatment with anti-rheumatic agent
has exact synonym: treatment with anti-rheumatic drug
has exact synonym: treatment with anti-rheumatic medication
has exact synonym: treatment with antirheumatic agent
has exact synonym: treatment with antirheumatic drug
has exact synonym: treatment with antirheumatic medication

molecular pathway modifying agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_52206
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_52206
IAO_0000115: Treatment with an agent that modifies a particular molecular pathway.
date: 2020-05-28T19:11:27Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: CHEBI:52206
has exact synonym: treatment with biochemical role

acetylcholinesterase inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38462
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38462
IAO_0000115: Use of an inhibitor that interferes with the action of enzyme acetylcholinesterase, which helps breaking down of acetylcholine into choline and acetic acid
date: 2020-05-28T19:16:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: AChE inhibitor drug treatment
has exact synonym: AChE inhibitor medication treatment
has exact synonym: acetylcholinesterase inhibitor agent therapy
has exact synonym: acetylcholinesterase inhibitor drug therapy
has exact synonym: treatment with EC 3.1.1.7 (acetylcholinesterase) inhibitor

cancer chemotherapy
type: Class
subclass of: antineoplastic therapy
subclass of: chemotherapy
IAO_0000115: Treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Chemotherapy may be given by mouth, injection, or infusion, or on the skin, depending on the type and stage of the cancer being treated. It may be given alone or with other treatments, such as surgery, radiation therapy, or biologic therapy.
date: 2020-05-29T20:29:34Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: anti-neoplastic chemotherapy
has broad synonym: antineoplastic chemotherapy
has db xref: NCRO:0000233
has exact synonym: cancer chemotherapeutic agent treatment
has exact synonym: cytotoxic antineoplastic agent therapy
has exact synonym: cytotoxic antineoplastic medication therapy
has exact synonym: cytotoxic cancer treatment
has exact synonym: treatment with cancer chemotherapeutic agent
has exact synonym: treatment with cancer chemotherapeutic drug
has exact synonym: treatment with cancer chemotherapeutic medication
comment: Although this term is used to describe any therapy involving the use of chemical-based agents, it is particularly used to refer to the use of chemical-based agents to treat cancer. Antineoplastic chemotherapy works by arresting or killing the growth and spread of cancer cells. Chemotherapy may also include agents that enhance immune function or alter hormonal activity.

Axiom
annotated source: cancer chemotherapy
annotated property: IAO_0000115
annotated target: Treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Chemotherapy may be given by mouth, injection, or infusion, or on the skin, depending on the type and stage of the cancer being treated. It may be given alone or with other treatments, such as surgery, radiation therapy, or biologic therapy.
has db xref: chemotherapy

Axiom
annotated source: cancer chemotherapy
annotated property: comment
annotated target: Although this term is used to describe any therapy involving the use of chemical-based agents, it is particularly used to refer to the use of chemical-based agents to treat cancer. Antineoplastic chemotherapy works by arresting or killing the growth and spread of cancer cells. Chemotherapy may also include agents that enhance immune function or alter hormonal activity.
has db xref: NCIT:C15632

chemotherapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: The use of synthetic or naturally-occurring chemicals for the treatment of diseases.
date: 2020-06-02T13:10:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15632
has db xref: OGMS:0000113
has exact synonym: chemotherapeutic agent treatment
has exact synonym: chemotherapeutic drug treatment
has exact synonym: treatment with a chemotherapeutic agent
has exact synonym: treatment with a chemotherapeutic drug
has exact synonym: treatment with a chemotherapeutic medication
comment: Although this term is used to describe any therapy involving the use of chemical-based agents, it is particularly used to refer to the use of chemical-based agents to treat cancer. Antineoplastic chemotherapy works by arresting or killing the growth and spread of cancer cells. Chemotherapy may also include agents that enhance immune function or alter hormonal activity.

Axiom
annotated source: chemotherapy
annotated property: IAO_0000115
annotated target: The use of synthetic or naturally-occurring chemicals for the treatment of diseases.
has db xref: NCIT:C15632

Axiom
annotated source: chemotherapy
annotated property: comment
annotated target: Although this term is used to describe any therapy involving the use of chemical-based agents, it is particularly used to refer to the use of chemical-based agents to treat cancer. Antineoplastic chemotherapy works by arresting or killing the growth and spread of cancer cells. Chemotherapy may also include agents that enhance immune function or alter hormonal activity.
has db xref: NCIT:C15632

enzyme inhibitor agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_23924
subclass of: molecular pathway modifying agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_23924
IAO_0000115: A therapy using a compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
date: 2020-06-02T18:44:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:23924
has exact synonym: enzyme inhibitor drug treatment
has exact synonym: enzyme inhibitor medication treatment
has exact synonym: treatment with enzyme inhibitor
has exact synonym: treatment with enzyme inhibitor agent
has exact synonym: treatment with enzyme inhibitor drug
has exact synonym: treatment with enzyme inhibitor medication
has exact synonym: treatment with enzyme inhibitor therapy

hyperglycemic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_76916
subclass of: glycemic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_76916
IAO_0000115: Use of a drug which increases blood glucose level.
date: 2020-06-02T20:39:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:76916
has exact synonym: treatment with hyperglycemic agent
has exact synonym: treatment with hyperglycemic drug
has exact synonym: treatment with hyperglycemic medication

antiatherogenic drug therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50855
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50855
IAO_0000115: Treatment with a cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries.
date: 2020-06-03T14:37:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:50855
has exact synonym: anti-atherogenic agent therapy
has exact synonym: treatment with anti-atherogenic agent
has exact synonym: treatment with anti-atherogenic drug
has exact synonym: treatment with anti-atherogenic medication
has exact synonym: treatment with anti-atherogenic therapy
has exact synonym: treatment with antiatherogenic agent
has exact synonym: treatment with antiatherogenic drug
has exact synonym: treatment with antiatherogenic medication

antiatherosclerotic drug therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_145947
subclass of: cardiovascular agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_145947
IAO_0000115: Treatment with a cardiovascular drug that prevents atherosclerosis, a disease in which the inside of an artery narrows due to the build-up of plaque.
date: 2020-06-03T14:51:06Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:145947
has exact synonym: anti-atherosclerotic agent therapy
has exact synonym: treatment with anti-atherosclerosis drug
has exact synonym: treatment with anti-atherosclerosis medication
has exact synonym: treatment with anti-atherosclerosis therapy
has exact synonym: treatment with anti-atherosclerotic agent
has exact synonym: treatment with anti-atherosclerotic drug
has exact synonym: treatment with anti-atherosclerotic medication
has exact synonym: treatment with antiatherosclerotic agent
has exact synonym: treatment with antiatherosclerotic drug
has exact synonym: treatment with antiatherosclerotic medication

ACE inhibitor therapy
type: Class
subclass of: RAAS inhibitor therapy
subclass of: vasodilator agent therapy
IAO_0000115: Use of a drug that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.
date: 2020-06-04T17:31:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:147289
has db xref: NCIT:C247
has exact synonym: Treatment with ACE inhibitor
has exact synonym: Treatment with angiotensin-converting enzyme inhibitor
has exact synonym: angiotensin-converting enzyme inhibitor therapy

angiotensin receptor blocker therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_61016
subclass of: receptor antagonist therapy
subclass of: RAAS inhibitor therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_61016
IAO_0000115: Treatment with a class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system.
date: 2020-06-04T17:31:52Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:61016
has db xref: NCIT:C66930
has exact synonym: ARB therapy
has exact synonym: treatment with ARB
has exact synonym: treatment with angiotensin II receptor antagonist
has exact synonym: treatment with angiotensin II receptor blocker
has exact synonym: treatment with angiotensin receptor antagonist
comment: A pharmaceutical agent that selectively inhibits angiotensin II receptor activation in the renin-angiotensin-aldosterone system reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. It is primarily used for the reduction of proteinuria and the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.
comment: Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.

Axiom
annotated source: angiotensin receptor blocker therapy
annotated property: comment
annotated target: A pharmaceutical agent that selectively inhibits angiotensin II receptor activation in the renin-angiotensin-aldosterone system reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. It is primarily used for the reduction of proteinuria and the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.
has db xref: NCIT:C66930

Axiom
annotated source: angiotensin receptor blocker therapy
annotated property: comment
annotated target: Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.
has db xref: NCIT:C66930

renin inhibitor therapy
type: Class
subclass of: RAAS inhibitor therapy
IAO_0000115: Treatment with a group of pharmaceutical drugs used primarily in treatment of essential hypertension. These drugs inhibit the first and rate-limiting step of the renin–angiotensin–aldosterone system, namely the conversion of angiotensinogen to angiotensin I.
date: 2020-06-04T17:32:06Z
creator: http://orcid.org/0000-0001-7941-2961

ACE1 inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35457
subclass of: enzyme inhibitor agent therapy
subclass of: ACE inhibitor therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35457
IAO_0000115: Use of a drug that inhibits angiotensin-converting enzyme (ACE) 1, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II.
date: 2020-06-04T18:03:38Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35457
has exact synonym: Treatment with ACE-1 inhibitor
has exact synonym: Treatment with ACE1 inhibitor
has exact synonym: angiotensin-converting enzyme-1 inhibitor therapy
has exact synonym: peptidyl-dipeptidase A inhibitor therapy
has exact synonym: treatment with EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
has exact synonym: treatment with angiotensin I-converting enzyme inhibitor

ACE2 inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_147289
subclass of: enzyme inhibitor agent therapy
subclass of: ACE inhibitor therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_147289
IAO_0000115: Use of a drug that inhibits angiotensin-converting enzyme (ACE) 2, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II.
date: 2020-06-04T18:17:34Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Treatment with ACE-2 inhibitor
has exact synonym: angiotensin-converting enzyme-2 inhibitor therapy
has exact synonym: treatment with EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor
has exact synonym: treatment with hACE2 inhibitor

metabotropic glutamate receptor antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_63963
subclass of: receptor antagonist therapy
subclass of: metabotropic glutamate receptor–targeting agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_63963
IAO_0000115: Use of a drug that selectively binds to and inhibits metabotropic glutamate receptors.
date: 2020-06-05T20:18:05Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:63963
has exact synonym: treatment with mGluR antagonist
has exact synonym: treatment with metabotropic glutamate receptor antagonist
has exact synonym: treatment with metabotropic glutamate receptor blockade
has exact synonym: treatment with metabotropic glutamate receptor blocker

NMDA receptor modulator agent therapy
type: Class
subclass of: glutamatergic pathway modifying agent therapy
IAO_0000115: Use of a drug that modulates the action of N-methyl-D-aspartate (NMDA) receptors.
date: 2020-06-08T17:47:39Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Treatment with NMDA receptor modulator

AMPA-targeting agent therapy
type: Class
subclass of: glutamatergic pathway modifying agent therapy
IAO_0000115: Treatment with an agent which regulates AMPA recepter signaling.
date: 2020-06-08T17:48:19Z
creator: http://orcid.org/0000-0001-7941-2961

metabotropic glutamate receptor–targeting agent therapy
type: Class
subclass of: glutamatergic pathway modifying agent therapy
IAO_0000115: Use of a drug that selectively binds to and regulates metabotropic glutamate receptors (mGluR).
date: 2020-06-08T17:48:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: treatment with mGluR modulator
has exact synonym: treatment with metabotropic glutamate receptor modulator

NMDA receptor agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64571
subclass of: NMDA receptor modulator agent therapy
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64571
IAO_0000115: Use of a drug that activates the action of N-methyl-D-aspartate (NMDA) receptors.
date: 2020-06-08T18:14:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64571
has exact synonym: treatment with NMDA receptor agonist

AMPA receptor agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_64102
subclass of: AMPA-targeting agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_64102
IAO_0000115: Use of a drug that selectively binds to and activates AMPA receptors.
date: 2020-06-09T13:52:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:64102
has exact synonym: treatment with AMPA receptor agonist

AMPA receptor antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_71014
subclass of: receptor antagonist therapy
subclass of: AMPA-targeting agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_71014
IAO_0000115: Use of a drug that selectively binds to and inhibits AMPA receptors.
date: 2020-06-09T13:52:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:71014
has exact synonym: treatment with AMPA receptor antagonist
has exact synonym: treatment with AMPA receptor blockade
has exact synonym: treatment with AMPA receptor blocker

antidiarrheal agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_55323
subclass of: gastrointestinal agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_55323
IAO_0000115: Treatment with an agent that is used to prevent or inhibit diarrhea.
date: 2020-06-09T15:32:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:55323
has exact synonym: anti-diarrheal agent therapy
has exact synonym: antidiarrhoeal agent therapy
has exact synonym: treatment with anti-diarrheal drug
has exact synonym: treatment with antidiarrheal agent
has exact synonym: treatment with antidiarrheal medication
has exact synonym: treatment with antidiarrhoeal drug

medical specialist evaluation
type: Class
subclass of: medical professional evaluation
IAO_0000115: A procedure where a physician reviews a patient's medical history, examines the patient, and makes recommendations as to care and treatment.
date: 2020-07-01T18:18:19Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009053
has exact synonym: medical specialist examination
has exact synonym: specialty medical professional consultation
has exact synonym: specialty medical professional evaluation

allergologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an allergologist who diagnoses and manages disorders involving allergies, asthma, and related conditions.
date: 2020-07-01T18:29:08Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: allergy and immunologist consultation
has exact synonym: allergy and immunologist doctor consultation
has exact synonym: allergy and immunologist doctor evaluation
has exact synonym: allergy and immunologist evaluation
has exact synonym: allergy and immunology specialist consultation
has exact synonym: allergy specialist evaluation
has exact synonym: consultation with allergy and immunologist
has exact synonym: referral to allergist and immunologist
has narrow synonym: allergist consultation
has narrow synonym: allergist doctor consultation
has narrow synonym: allergist doctor evaluation
has narrow synonym: allergist evaluation
has narrow synonym: consultation with allergist
has narrow synonym: evaluation by an immunologist
has narrow synonym: immunologist evaluation

Axiom
annotated source: allergologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an allergologist who diagnoses and manages disorders involving allergies, asthma, and related conditions.
has db xref: ABMS.org

anesthesiology specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a physician who provides anesthesia for patients undergoing surgical, obstetric, diagnostic or therapeutic procedures while monitoring the patient's condition and supporting vital organ functions. The anesthesiologist also diagnoses and treats acute, chronic and/or cancer pain as well as provides resuscitation and medical management for patients with critical illnesses and severe injuries.
date: 2020-07-01T18:42:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C93067
has exact synonym: anesthesiologist consultation
has exact synonym: anesthesiologist evaluation
has exact synonym: anesthesiology doctor consultation
has exact synonym: anesthesiology doctor evaluation
has exact synonym: anesthesiology specialist consultation
has exact synonym: consultation with anesthesiologist
has exact synonym: referral to anesthesiologist

Axiom
annotated source: anesthesiology specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician who provides anesthesia for patients undergoing surgical, obstetric, diagnostic or therapeutic procedures while monitoring the patient's condition and supporting vital organ functions. The anesthesiologist also diagnoses and treats acute, chronic and/or cancer pain as well as provides resuscitation and medical management for patients with critical illnesses and severe injuries.
has db xref: abms.org

pediatric anesthesiology specialist evaluation
type: Class
subclass of: anesthesiology specialist evaluation
IAO_0000115: An evaluation by an anesthesiologist who specializes in Pediatric Anesthesiology. This specialist provides anesthesia for neonates, infants, children and adolescents undergoing surgical, diagnostic or therapeutic procedures as well as appropriate pre- and post-operative care, advanced life support, and acute pain management.
date: 2020-07-01T18:48:51Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with pediatric anesthesiologist
has exact synonym: pediatric anesthesiologist consultation
has exact synonym: pediatric anesthesiologist evaluation
has exact synonym: pediatric anesthesiology specialist consultation

colon and rectal surgery specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a colon and rectal surgeon who diagnoses and treats various diseases of the small intestine, colon, rectum, anal canal and perianal area including the organs and tissues related with primary intestinal diseases (liver, urinary and female reproductive system). This specialist treats conditions such as hemorrhoids, fissures (painful tears in the anal lining), abscesses and fistulas (infections located around the anus and rectum). A colon and rectal surgeon diagnoses and treats problems of the intestine and colon such as cancer, polyps (precancerous growths) and inflammatory conditions.
date: 2020-07-01T19:08:36Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: colon and rectal surgeon consultation
has exact synonym: colon and rectal surgeon evaluation
has exact synonym: colon and rectal surgery specialist consultation
has exact synonym: colorectal surgeon consultation
has exact synonym: colorectal surgeon evaluation
has exact synonym: consultation with colon and rectal surgeon
has exact synonym: consultation with colon and rectal surgery specialist
has exact synonym: consultation with colorectal surgeon
has exact synonym: referral to a colon and rectal surgeon
has exact synonym: referral to colorectal surgeon

Axiom
annotated source: colon and rectal surgery specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a colon and rectal surgeon who diagnoses and treats various diseases of the small intestine, colon, rectum, anal canal and perianal area including the organs and tissues related with primary intestinal diseases (liver, urinary and female reproductive system). This specialist treats conditions such as hemorrhoids, fissures (painful tears in the anal lining), abscesses and fistulas (infections located around the anus and rectum). A colon and rectal surgeon diagnoses and treats problems of the intestine and colon such as cancer, polyps (precancerous growths) and inflammatory conditions.
has db xref: abms.org

dermatology specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a physician with training and expertise in the diagnosis and medical/surgical management of diseases of the skin, hair and nails, and mucous membranes.
date: 2020-07-01T19:12:58Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009055
has exact synonym: consultation with a dermatologist
has exact synonym: dermatologist consultation
has exact synonym: dermatologist evaluation
has exact synonym: dermatologist examination
has exact synonym: dermatology specialist consultation
has exact synonym: examination by dermatologist
has exact synonym: referral to a dermatologist

Axiom
annotated source: dermatology specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician with training and expertise in the diagnosis and medical/surgical management of diseases of the skin, hair and nails, and mucous membranes.
has db xref: abms.org

emergency medicine specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a physician who specializes in immediate decision making and action necessary to prevent death or any further disability both in the pre-hospital setting by directing emergency medical technicians and in the emergency department. This specialist provides immediate recognition, evaluation, care, stabilization and disposition of a generally diversified population of adult and pediatric patients in response to acute illness and injury.
date: 2020-07-01T19:23:12Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009056
has exact synonym: ED examination
has exact synonym: ER examination
has exact synonym: assessment by emergency medicine specialist
has exact synonym: emergency department physician examination
has exact synonym: emergency medicine specialist assessment
has exact synonym: emergency room doctor evaluation
has exact synonym: emergency room physician examination
has exact synonym: examination by emergency medicine specialst

Axiom
annotated source: emergency medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician who specializes in immediate decision making and action necessary to prevent death or any further disability both in the pre-hospital setting by directing emergency medical technicians and in the emergency department. This specialist provides immediate recognition, evaluation, care, stabilization and disposition of a generally diversified population of adult and pediatric patients in response to acute illness and injury.
has db xref: abms.org

family medicine specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a physician who provides front-line health care that is accessible, high quality, comprehensive and continuous over time for people of all ages, life stages, backgrounds and conditions. The specialists care for individuals and for entire families, from birth through the end of life, including a broad range of preventive care; healthy lifestyle counseling; mental health care; care of acute illnesses; management of chronic diseases, including patients with multi-morbidity. When needed, they also provide referral and coordination of care with other specialists.
date: 2020-07-01T19:39:31Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009057
has exact synonym: consultation with family medicine specialist
has exact synonym: examination by family medicine specialist
has exact synonym: family medicine specialist consultation

Axiom
annotated source: family medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician who provides front-line health care that is accessible, high quality, comprehensive and continuous over time for people of all ages, life stages, backgrounds and conditions. The specialists care for individuals and for entire families, from birth through the end of life, including a broad range of preventive care; healthy lifestyle counseling; mental health care; care of acute illnesses; management of chronic diseases, including patients with multi-morbidity. When needed, they also provide referral and coordination of care with other specialists.
has db xref: abms.org

geriatric medicine specialist evaluation
type: Class
subclass of: family medicine specialist evaluation
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by a physician with special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects of illness in the elderly. This specialist cares for geriatric patients in the patient’s home, the office, long-term care settings such as nursing homes, and the hospital.
date: 2020-07-01T19:52:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by geriatric medicine specialist
has exact synonym: consultation with geriatric medicine specialist
has exact synonym: evaluation by geriatric medicine specialist
has exact synonym: geriatric medicine specialist consultation
has exact synonym: referral to geriatric medicine specialist

Axiom
annotated source: geriatric medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician with special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects of illness in the elderly. This specialist cares for geriatric patients in the patient’s home, the office, long-term care settings such as nursing homes, and the hospital.
has db xref: abms.org

hospice and palliative medicine specialist evaluation
type: Class
subclass of: palliative care
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a physician who specializes in Hospice and Palliative Medicine who provides care to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This specialist works with an interdisciplinary hospice or palliative care team to optimize quality of life while addressing the physical, psychological, social and spiritual needs of both patient and family.
date: 2020-07-01T19:53:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with hospice and palliative medicine specialist
has exact synonym: hospice and palliative medicine specialist consultation
has exact synonym: referral to hospice and palliative medicine specialist
has narrow synonym: assessment by palliative care specialist
has narrow synonym: consultation with palliative care specialist
has narrow synonym: evaluation by palliative care specialist
has narrow synonym: palliative care specialist consultation
has narrow synonym: palliative care specialist evaluation
has narrow synonym: palliative care specialist referral
has narrow synonym: referral to palliative care specialist

pain medicine specialist evaluation
type: Class
subclass of: emergency medicine specialist evaluation
subclass of: family medicine specialist evaluation
subclass of: physiatrist evaluation
subclass of: radiologist evaluation
subclass of: psychiatry and neurology specialist evaluation
IAO_0000115: An assessment by a physician who diagnoses and treats patients experiencing problems with acute or chronic pain, or pain related to cancer, in both hospital and outpatient settings and coordinates care needs with other specialists.
date: 2020-07-01T19:56:48Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by pain medicine specialist
has exact synonym: consultation with pain medicine specialist
has exact synonym: evaluation by pain medicine specialist
has exact synonym: pain medicine specialist consultation
has exact synonym: referral to a pain medicine specialist

Axiom
annotated source: pain medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a physician who diagnoses and treats patients experiencing problems with acute or chronic pain, or pain related to cancer, in both hospital and outpatient settings and coordinates care needs with other specialists.
has db xref: abms.org

sports medicine specialist evaluation
type: Class
subclass of: emergency medicine specialist evaluation
subclass of: family medicine specialist evaluation
subclass of: internal medicine specialist evaluation
subclass of: pediatrician evaluation
subclass of: physiatrist evaluation
IAO_0000115: An assesment a specialist focuses on preventing, diagnosing, and treating injuries related to participating in sports and/or exercise. In addition to the study of those fields that focus on prevention, diagnosis, treatment, and management of injuries, Sports Medicine specialists also deal with illnesses and diseases that might have effects on health and physical performance.
date: 2020-07-01T19:59:07Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with sports medicine specialist
has exact synonym: referral to a sports medicine specialist
has exact synonym: sports medicine specialist consultation

Axiom
annotated source: sports medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assesment a specialist focuses on preventing, diagnosing, and treating injuries related to participating in sports and/or exercise. In addition to the study of those fields that focus on prevention, diagnosis, treatment, and management of injuries, Sports Medicine specialists also deal with illnesses and diseases that might have effects on health and physical performance.
has db xref: abms.org

sleep medicine specialist evaluation
type: Class
subclass of: anesthesiology specialist evaluation
subclass of: family medicine specialist evaluation
subclass of: internal medicine specialist evaluation
subclass of: otolaryngologist evaluation
subclass of: pediatrician evaluation
subclass of: psychiatry and neurology specialist evaluation
IAO_0000115: An assessment with a specialist who has expertise in the diagnosis and management of clinical conditions that occur during sleep, that disturb sleep, or that are affected by disturbances in the wake-sleep cycle. This specialist is skilled in the analysis and interpretation of comprehensive polysomnography, and well versed in emerging research and management of a sleep laboratory.
date: 2020-07-01T20:01:47Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by sleep medicine specialist
has exact synonym: assessment by sleep specialist
has exact synonym: consultation with sleep medicine specialist
has exact synonym: consultation with sleep specialist
has exact synonym: evaluation by sleep medicine specialist
has exact synonym: evaluation by sleep specialist
has exact synonym: referral to sleep medicine specialist
has exact synonym: referral to sleep specialist
has exact synonym: sleep medicine specialist consultation
has exact synonym: sleep specialist assessment
has exact synonym: sleep specialist consultation
has exact synonym: sleep specialist evaluation
has exact synonym: sleep specialist referral
has related synonym: sleep study evaluation

Axiom
annotated source: sleep medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment with a specialist who has expertise in the diagnosis and management of clinical conditions that occur during sleep, that disturb sleep, or that are affected by disturbances in the wake-sleep cycle. This specialist is skilled in the analysis and interpretation of comprehensive polysomnography, and well versed in emerging research and management of a sleep laboratory.
has db xref: abms.org

internal medicine specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a personal physician who provides long-term, comprehensive care in the office and in the hospital, managing both common and complex illnesses of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and the digestive, respiratory and vascular systems. Internists are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.
date: 2020-07-01T20:07:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with internal medicine specialist
has exact synonym: consultation with internist
has exact synonym: internal medicine specialist consultation
has exact synonym: internist consultation
has exact synonym: internist evaluation
has exact synonym: referral to an internal medicine specialist
has exact synonym: referral to an internist

Axiom
annotated source: internal medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a personal physician who provides long-term, comprehensive care in the office and in the hospital, managing both common and complex illnesses of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and the digestive, respiratory and vascular systems. Internists are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.
has db xref: abms.org

adolescent medicine specialist evaluation
type: Class
subclass of: family medicine specialist evaluation
subclass of: internal medicine specialist evaluation
subclass of: pediatrician evaluation
IAO_0000115: An assessment with a multidisciplinary health care specialist trained in the unique physical, psychological and social characteristics of adolescents, their health care problems and needs.
date: 2020-07-01T20:13:15Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: adolescent medicine specialist consultation
has exact synonym: adolescent medicine specialist evaluation
has exact synonym: assessment by adolescent medicine specialist
has exact synonym: consultation with adolescent medicine specialist
has exact synonym: evaluation by adolescent medicine specialist
has exact synonym: referral to adolescent medicine specialist

Axiom
annotated source: adolescent medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment with a multidisciplinary health care specialist trained in the unique physical, psychological and social characteristics of adolescents, their health care problems and needs.
has db xref: abms.org

cardiologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions, such as heart attacks and life-threatening, abnormal heartbeat rhythms.
date: 2020-07-01T20:16:52Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by cardiologist
has exact synonym: cardiologist consultation
has exact synonym: cardiologist evaluation
has exact synonym: cardiologist referral
has exact synonym: cardiovascular disease internist consultation
has exact synonym: cardiovascular disease internist evaluation
has exact synonym: consultation with cardiologist
has exact synonym: consultation with cardiovascular disease internist
has exact synonym: consultation with internal medicine cardiovascular disease specialist
has exact synonym: evaluation by cardiologist
has exact synonym: internal medicine cardiovascular disease specialist consultation
has exact synonym: referral to cardiologist
has exact synonym: referral to cardiovascular disease internist

Axiom
annotated source: cardiologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions, such as heart attacks and life-threatening, abnormal heartbeat rhythms.
has db xref: abms.org

clinical cardiac electrophysiologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by a specialist who specializes in intricate technical procedures to evaluate heart rhythms and determine appropriate treatment.
date: 2020-07-01T20:30:10Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with clinical cardiac electrophysiologist
has exact synonym: consultation with clinical cardiac electrophysiology specialist
has exact synonym: internal medicine clinical cardiac electrophysiologist consultation
has exact synonym: internal medicine clinical cardiac electrophysiology specialist consultation
has exact synonym: internal medicine clinical cardiac electrophysiology specialist evaluation
has exact synonym: referral to a clinical electrophysiologist

Axiom
annotated source: clinical cardiac electrophysiologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a specialist who specializes in intricate technical procedures to evaluate heart rhythms and determine appropriate treatment.
has db xref: abms.org

critical care medicine internist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment with an internist trained in critical care medicine who has expertise in the diagnosis, treatment and support of critically ill and injured patients, particularly trauma victims and patients with multiple organ dysfunction.
date: 2020-07-01T20:35:47Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with critical care medicine internist
has exact synonym: consultation with internal medicine critical care medicine specialist
has exact synonym: internal medicine critical care medicine consultation
has exact synonym: internal medicine critical care medicine evaluation
has exact synonym: referral to critical care internist

endocrinologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment with an internist who specializes in the diagnosis and management of disorders of hormones and their actions, metabolic disorders, and neoplasia of the endocrine glands. This specialist cares for patients with diabetes mellitus, thyroid disorders, disorders of calcium and bone, hyperlipidemia, obesity and nutritional disorders, pituitary disorders, reproductive and gonadal disorders, adrenal diseases, and endocrine hypertension.
date: 2020-07-01T20:43:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with endocrinologist
has exact synonym: consultation with endocrinology, diabetes and metabolism specialist
has exact synonym: endocrinologist consultation
has exact synonym: endocrinology, diabetes and metabolism specialist consultation
has exact synonym: endocrinology, diabetes and metabolism specialist evaluation
has exact synonym: referral to endocrinologist

Axiom
annotated source: endocrinologist evaluation
annotated property: IAO_0000115
annotated target: An assessment with an internist who specializes in the diagnosis and management of disorders of hormones and their actions, metabolic disorders, and neoplasia of the endocrine glands. This specialist cares for patients with diabetes mellitus, thyroid disorders, disorders of calcium and bone, hyperlipidemia, obesity and nutritional disorders, pituitary disorders, reproductive and gonadal disorders, adrenal diseases, and endocrine hypertension.
has db xref: abms.org

gastroenterologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An evaluation with an internist who specializes in diagnosis and treatment of diseases of the digestive organs including the stomach, bowels, liver and gallbladder. This specialist treats conditions such as abdominal pain, ulcers, diarrhea, cancer and jaundice and performs complex diagnostic and therapeutic procedures using endoscopes to visualize internal organs.
date: 2020-07-01T20:46:33Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with gastroenterologist
has exact synonym: consultation with gastroenterology specialist
has exact synonym: gastroenterologist consultation
has exact synonym: gastroenterology specialist evaluation
has exact synonym: referral to gastroenterologist

Axiom
annotated source: gastroenterologist evaluation
annotated property: IAO_0000115
annotated target: An evaluation with an internist who specializes in diagnosis and treatment of diseases of the digestive organs including the stomach, bowels, liver and gallbladder. This specialist treats conditions such as abdominal pain, ulcers, diarrhea, cancer and jaundice and performs complex diagnostic and therapeutic procedures using endoscopes to visualize internal organs.
has db xref: abms.org

hematologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, clotting disorders, sickle cell disease, hemophilia, leukemia and lymphoma.
date: 2020-07-01T21:00:28Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with hematologist
has exact synonym: hematologist consultation
has exact synonym: hematology specialist consultation
has exact synonym: hematology specialist evaluation
has exact synonym: referral to hematologist

Axiom
annotated source: hematologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, clotting disorders, sickle cell disease, hemophilia, leukemia and lymphoma.
has db xref: abms.org

infectious disease internist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who deals with infectious diseases of all types and in all organ systems. Infectious disease specialists may also have expertise in preventive medicine and travel medicine.
date: 2020-07-02T17:10:50Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with infectious disease specialist
has exact synonym: infectious disease specialist consultation
has exact synonym: infectious disease specialist evaluation
has exact synonym: referral to infectious disease internist

Axiom
annotated source: infectious disease internist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who deals with infectious diseases of all types and in all organ systems. Infectious disease specialists may also have expertise in preventive medicine and travel medicine.
has db xref: abms.org

medical oncologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who specializes in the diagnosis and treatment of all types of cancer and other benign and malignant tumors. This specialist decides on and administers therapy for these malignancies, as well as consults with surgeons and radiotherapists on other treatments for cancer.
date: 2020-07-02T17:50:50Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with medical oncologist
has exact synonym: consultation with medical oncology internist
has exact synonym: medical oncologist consultation
has exact synonym: medical oncology internist consultation
has exact synonym: medical oncology internist evaluation
has exact synonym: referral to oncologist

Axiom
annotated source: medical oncologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who specializes in the diagnosis and treatment of all types of cancer and other benign and malignant tumors. This specialist decides on and administers therapy for these malignancies, as well as consults with surgeons and radiotherapists on other treatments for cancer.
has db xref: abms.org

nephrologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who treats disorders of the kidney, high blood pressure, fluid and mineral balance, and dialysis of body wastes when the kidneys do not function. This specialist consults with surgeons about kidney transplantation.
date: 2020-07-02T18:23:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with nephrologist
has exact synonym: consultation with nephrology internist
has exact synonym: nephrologist consultation
has exact synonym: nephrology internist consultation
has exact synonym: nephrology internist evaluation
has exact synonym: referral to nephrologist

Axiom
annotated source: nephrologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who treats disorders of the kidney, high blood pressure, fluid and mineral balance, and dialysis of body wastes when the kidneys do not function. This specialist consults with surgeons about kidney transplantation.
has db xref: abms.org

pulmonologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who treats diseases of the lungs and airways. The specialist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational and environmental diseases, bronchitis, sleep disorders, emphysema and other complex disorders of the lungs.
date: 2020-07-02T18:32:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with pulmonary disease internist
has exact synonym: consultation with pulmonary disease specialist
has exact synonym: consultation with pulmonologist
has exact synonym: pulmonary disease internist consultation
has exact synonym: pulmonary disease internist evaluation
has exact synonym: pulmonologist consultation
has exact synonym: referral to pulmonologist

Axiom
annotated source: pulmonologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who treats diseases of the lungs and airways. The specialist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational and environmental diseases, bronchitis, sleep disorders, emphysema and other complex disorders of the lungs.
has db xref: abms.org

rheumatologist evaluation
type: Class
subclass of: internal medicine specialist evaluation
IAO_0000115: An assessment by an internist who treats diseases of joints, muscle, bones and tendons. This specialist diagnoses and treats arthritis, back pain, muscle strains, common athletic injuries and collagen diseases.
date: 2020-07-02T19:00:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with rheumatologist
has exact synonym: consultation with rheumatology internist
has exact synonym: referral to rhematologist
has exact synonym: rheumatologist consultation
has exact synonym: rheumatology internist consultation
has exact synonym: rheumatology internist evaluation
has exact synonym: rheumatology specialist consultation
has exact synonym: rheumatology specialist evaluation

Axiom
annotated source: rheumatologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by an internist who treats diseases of joints, muscle, bones and tendons. This specialist diagnoses and treats arthritis, back pain, muscle strains, common athletic injuries and collagen diseases.
has db xref: abms.org

clinical biochemical geneticist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment with a specialist who directs and interprets a wide range of specialized, laboratory biochemical genetic analyses relevant to the diagnosis and management of inherited metabolic disorders. The specialist acts as a consultant regarding laboratory diagnosis on a broad range of inborn errors of metabolism.
date: 2020-07-02T20:14:07Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: clinical biochemical geneticist consultation
has exact synonym: consultation with clinical biochemical geneticist
has exact synonym: referral to a clinical biochemical geneticist

Axiom
annotated source: clinical biochemical geneticist evaluation
annotated property: IAO_0000115
annotated target: An assessment with a specialist who directs and interprets a wide range of specialized, laboratory biochemical genetic analyses relevant to the diagnosis and management of inherited metabolic disorders. The specialist acts as a consultant regarding laboratory diagnosis on a broad range of inborn errors of metabolism.
has db xref: abms.org

clinical genetics and genomics specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment with a specialist who provides comprehensive diagnostic, management, therapeutic, and counseling services for individuals and families at risk for clinical disorders with a genetic basis. The specialist is trained to evaluate individuals of all ages for hereditary conditions.
date: 2020-07-02T20:16:59Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: clinical geneticist consultation
has exact synonym: clinical geneticist evaluation
has exact synonym: clinical genetics and genomics specialist consultation
has exact synonym: consultation with clinical geneticist
has exact synonym: consultation with clinical genetics and genomics specialist
has exact synonym: referral to a clinical geneticist

Axiom
annotated source: clinical genetics and genomics specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment with a specialist who provides comprehensive diagnostic, management, therapeutic, and counseling services for individuals and families at risk for clinical disorders with a genetic basis. The specialist is trained to evaluate individuals of all ages for hereditary conditions.
has db xref: abms.org

clinical laboratory geneticist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment or consultation by a diplomate certified in Laboratory Genetics and Genomics who directs and interprets both clinical cytogenetic and molecular genetic analyses relevant to the diagnosis and management of human genetic disease. This specialist acts as a consultant in laboratory diagnoses for a broad range of molecular and chromosomal-based disorders, including both inherited and acquired conditions.
date: 2020-07-02T20:29:00Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: clinical laboratory geneticist evaluation
annotated property: IAO_0000115
annotated target: An assessment or consultation by a diplomate certified in Laboratory Genetics and Genomics who directs and interprets both clinical cytogenetic and molecular genetic analyses relevant to the diagnosis and management of human genetic disease. This specialist acts as a consultant in laboratory diagnoses for a broad range of molecular and chromosomal-based disorders, including both inherited and acquired conditions.
has db xref: abms.org

neurological surgery specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by this specialist provides care for adult and pediatric patients in the treatment of pain or pathological processes that may modify the function or activity of the central nervous system (e.g., brain, hypophysis, and spinal cord), the peripheral nervous system (e.g., cranial, spinal, and peripheral nerves), the autonomic nervous system, the supporting structures of these systems (e.g., meninges, skull & skull base, and vertebral column), and their vascular supply (e.g., intracranial, extracranial, and spinal vasculature).
date: 2020-07-08T15:24:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17722
has exact synonym: consultation with neurological surgeon
has exact synonym: consultation with neurological surgery specialist
has exact synonym: consultation with neurosurgeon
has exact synonym: neurological surgeon consultation
has exact synonym: neurological surgeon evaluation
has exact synonym: neurological surgery specialist consultation
has exact synonym: neurosurgeon consultation
has exact synonym: neurosurgeon evaluation
has exact synonym: referral to neurosurgeon

Axiom
annotated source: neurological surgery specialist evaluation
annotated property: IAO_0000115
annotated target: An assessment by this specialist provides care for adult and pediatric patients in the treatment of pain or pathological processes that may modify the function or activity of the central nervous system (e.g., brain, hypophysis, and spinal cord), the peripheral nervous system (e.g., cranial, spinal, and peripheral nerves), the autonomic nervous system, the supporting structures of these systems (e.g., meninges, skull & skull base, and vertebral column), and their vascular supply (e.g., intracranial, extracranial, and spinal vasculature).
has db xref: abms.org

nuclear medicine specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An evaluation by a specialist that uses molecular tracers (usually labeled with radioactive atoms) for diagnosis and therapy.
date: 2020-07-08T17:46:13Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with nuclear medicine specialist
has exact synonym: nuclear medicine specialist consultation
has exact synonym: referral to nuclear medicine specialist
comment: These labeled tracers are most often used to produce images that provide information about organ function, as well as cellular function on a molecular level (molecular imaging). Molecular imaging can be combined with anatomical imaging by using specialized cameras. The most common diagnostic applications of Nuclear Medicine include the early detection of coronary artery disease, cancer diagnosis and staging and the evaluation of the effect of cancer treatment. The fusion of molecular and anatomical information increases diagnostic accuracy and changes medical management. Radioactive materials are also used to treat a variety of health problems, including thyroid disorders and cancer.

Axiom
annotated source: nuclear medicine specialist evaluation
annotated property: IAO_0000115
annotated target: An evaluation by a specialist that uses molecular tracers (usually labeled with radioactive atoms) for diagnosis and therapy.
has db xref: abms.org

Axiom
annotated source: nuclear medicine specialist evaluation
annotated property: comment
annotated target: These labeled tracers are most often used to produce images that provide information about organ function, as well as cellular function on a molecular level (molecular imaging). Molecular imaging can be combined with anatomical imaging by using specialized cameras. The most common diagnostic applications of Nuclear Medicine include the early detection of coronary artery disease, cancer diagnosis and staging and the evaluation of the effect of cancer treatment. The fusion of molecular and anatomical information increases diagnostic accuracy and changes medical management. Radioactive materials are also used to treat a variety of health problems, including thyroid disorders and cancer.
has db xref: abms.org

obstetrics and gynecology specialist evaluation
type: Class
subclass of: medical specialist evaluation
subclass of: obstetrics and gynecology procedure
IAO_0000115: An evaluation with a specialist who focuses on the health of women before, during and after childbearing years, diagnosing and treating conditions of the reproductive system and associated disorders.
date: 2020-07-08T17:53:55Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009059
has exact synonym: OB/GYN specialist consultation
has exact synonym: OB/GYN specialist evaluation
has exact synonym: consultation OB/GYN specialist
has exact synonym: consultation obstetrician/gynecologist
has exact synonym: consultation with obstetrics and gynecology specialist
has exact synonym: examination by ob/gyn specialist
has exact synonym: ob/gyn examination
has exact synonym: obstetrician/gynecologist consultation
has exact synonym: obstetrician/gynecologist evaluation
has exact synonym: obstetrics and gynecology specialist consultation
has exact synonym: obstetrics/gynecology specialist consultation
has exact synonym: obstetrics/gynecology specialist evaluation
has exact synonym: referral to OB/GYN specialist
has narrow synonym: gynecologist examination
has narrow synonym: obstetrics examination

Axiom
annotated source: obstetrics and gynecology specialist evaluation
annotated property: IAO_0000115
annotated target: An evaluation with a specialist who focuses on the health of women before, during and after childbearing years, diagnosing and treating conditions of the reproductive system and associated disorders.
has db xref: abms.org

ophthalmologist evaluation
type: Class
subclass of: medical specialist evaluation
subclass of: ophthalmic diagnostic procedure
IAO_0000115: An evaluation by a specialist focused on the medical and surgical care of the eyes. Ophthalmologists are the only physicians medically trained to manage the complete range of the eye and vision care. They can prescribe glasses and contact lenses, dispense medications, diagnose and treat eye conditions and diseases and perform surgeries.
date: 2020-07-08T20:14:31Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009060
has exact synonym: consultation with ophthalmologist
has exact synonym: examination by ophthalmologist
has exact synonym: ophthalmologist consultation
has exact synonym: ophthalmologist examination
has exact synonym: ophthalmologist referral
has exact synonym: ophthalmology specialist consultation
has exact synonym: ophthalmology specialist evaluation
has exact synonym: referral to ophthalmologist
has exact synonym: referral to ophthalmology specialist
has related synonym: referral to optometrist

Axiom
annotated source: ophthalmologist evaluation
annotated property: IAO_0000115
annotated target: An evaluation by a specialist focused on the medical and surgical care of the eyes. Ophthalmologists are the only physicians medically trained to manage the complete range of the eye and vision care. They can prescribe glasses and contact lenses, dispense medications, diagnose and treat eye conditions and diseases and perform surgeries.
has db xref: abms.org

sports medicine orthopedist evaluation
type: Class
subclass of: orthopedic surgeon evaluation
IAO_0000115: An evaluation by a specialist who has expertise in the surgical and medical care for all structures of the musculoskeletal system directly affected by participation in sporting activity. This specialist is proficient in areas including conditioning, training and fitness, athletic performance and the impact of dietary supplements, pharmaceuticals, and nutrition on performance and health, coordination of care within the team setting utilizing other health care professionals, field evaluation and management, soft tissue biomechanics and injury healing and repair. Knowledge and understanding of the principles and techniques of rehabilitation, athletic equipment and orthotic devices enables the specialist to prevent and manage athletic injuries.
date: 2020-07-08T20:31:50Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with sports medicine orthopedic surgeon
has exact synonym: referral to sports medicine orthopedic surgeon
has exact synonym: referral to sports medicine orthopedist
has exact synonym: sports medicine orthopedic surgeon consultation
has exact synonym: sports medicine orthopedic surgeon evaluation
has exact synonym: sports medicine orthopedist consultation
has exact synonym: sports medicine orthopedist referral

Axiom
annotated source: sports medicine orthopedist evaluation
annotated property: IAO_0000115
annotated target: An evaluation by a specialist who has expertise in the surgical and medical care for all structures of the musculoskeletal system directly affected by participation in sporting activity. This specialist is proficient in areas including conditioning, training and fitness, athletic performance and the impact of dietary supplements, pharmaceuticals, and nutrition on performance and health, coordination of care within the team setting utilizing other health care professionals, field evaluation and management, soft tissue biomechanics and injury healing and repair. Knowledge and understanding of the principles and techniques of rehabilitation, athletic equipment and orthotic devices enables the specialist to prevent and manage athletic injuries.
has db xref: abms.org

hand surgeon evaluation
type: Class
subclass of: orthopedic surgeon evaluation
subclass of: plastic surgeon evaluation
subclass of: general surgeon evaluation
IAO_0000115: An assessment by a specialist with expertise in the surgical, medical and rehabilitative care of patients with diseases, injuries, and disorders affecting the hand, wrist and forearm.
date: 2020-07-08T20:34:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with hand surgeon
has exact synonym: consultation with orthopedic hand surgeon
has exact synonym: hand surgeon consultation
has exact synonym: referral to hand surgeon
has exact synonym: referral to orthopedic hand surgeon
comment: Common conditions treated by a hand surgeon include carpal tunnel syndrome, trigger fingers, ganglia (lumps), sports injuries to the hand and wrist, and hand injuries involving cut tendons, nerves and arteries. Hand Surgeons may be General Surgeons, Orthopedic Surgeons or Plastic Surgeons who have received additional training in this area.

Axiom
annotated source: hand surgeon evaluation
annotated property: IAO_0000115
annotated target: An assessment by a specialist with expertise in the surgical, medical and rehabilitative care of patients with diseases, injuries, and disorders affecting the hand, wrist and forearm.
has db xref: abms.org

Axiom
annotated source: hand surgeon evaluation
annotated property: comment
annotated target: Common conditions treated by a hand surgeon include carpal tunnel syndrome, trigger fingers, ganglia (lumps), sports injuries to the hand and wrist, and hand injuries involving cut tendons, nerves and arteries. Hand Surgeons may be General Surgeons, Orthopedic Surgeons or Plastic Surgeons who have received additional training in this area.
has db xref: abms.org

otolaryngologist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a specialist who provides medical and/or surgical therapy or prevention of diseases, allergies, neoplasms, deformities, disorders and/or injuries of the ears, nose, sinuses, throat, respiratory and upper alimentary systems, face, jaws and the other head and neck systems.
date: 2020-07-09T16:10:20Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009061
has exact synonym: consultation by otolaryngology specialist
has exact synonym: consultation with head and neck surgeon
has exact synonym: consultation with otolaryngologist
has exact synonym: evaluation by otolaryngologist
has exact synonym: examination by otolaryngologist
has exact synonym: head and neck surgeon consultation
has exact synonym: head and neck surgeon evaluation
has exact synonym: head and neck surgeon referral
has exact synonym: otolaryngologist consultation
has exact synonym: otolaryngologist referral
has exact synonym: otolaryngology specialist consultation
has exact synonym: otolaryngology specialist evaluation
has exact synonym: otolaryngology specialist referral
has exact synonym: otorhinolaryngologist evaluation
has exact synonym: referral to head and neck surgeon
has exact synonym: referral to otolaryngologist
comment: Head and neck oncology, facial plastic and reconstructive surgery and the treatment of disorders of hearing and voice are fundamental areas of expertise.

Axiom
annotated source: otolaryngologist evaluation
annotated property: IAO_0000115
annotated target: An assessment by a specialist who provides medical and/or surgical therapy or prevention of diseases, allergies, neoplasms, deformities, disorders and/or injuries of the ears, nose, sinuses, throat, respiratory and upper alimentary systems, face, jaws and the other head and neck systems.
has db xref: abms.org

Axiom
annotated source: otolaryngologist evaluation
annotated property: comment
annotated target: Head and neck oncology, facial plastic and reconstructive surgery and the treatment of disorders of hearing and voice are fundamental areas of expertise.
has db xref: abms.org

pediatrician evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment by a specialist concerned with the physical, emotional, and social health of children from birth to young adulthood.
date: 2020-07-09T17:48:27Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009063
has exact synonym: evaluation by pediatrician
has exact synonym: examination by pediatrician
has exact synonym: pediatric examination
has exact synonym: pediatrician consultation
comment: Pediatric care encompasses a broad spectrum of health services ranging from preventive health care to the diagnosis and treatment of acute and chronic diseases. Pediatricians understand the many factors that affect the growth and development of children. They understand that children are not simply small adults. Children change rapidly, and they must be approached with an appreciation for their stage of physical and mental development.

Axiom
annotated source: pediatrician evaluation
annotated property: IAO_0000115
annotated target: An assessment by a specialist concerned with the physical, emotional, and social health of children from birth to young adulthood.
has db xref: abms.org

Axiom
annotated source: pediatrician evaluation
annotated property: comment
annotated target: Pediatric care encompasses a broad spectrum of health services ranging from preventive health care to the diagnosis and treatment of acute and chronic diseases. Pediatricians understand the many factors that affect the growth and development of children. They understand that children are not simply small adults. Children change rapidly, and they must be approached with an appreciation for their stage of physical and mental development.
has db xref: abms.org

developmental-behavior pediatrician evaluation
type: Class
subclass of: pediatrician evaluation
IAO_0000115: An evaluation with a specialist who possesses special skills, training and experience to foster understanding and promotion of optimal development of children and families through research, education, clinical care and advocacy efforts. This physician assists in the prevention, diagnosis and management of developmental difficulties and problematic behaviors in children and in the family dysfunctions that compromise children’s development.
date: 2020-07-09T18:05:01Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with developmental-behavior pediatrician
has exact synonym: developmental-behavior pediatrician consultation
has exact synonym: developmental-behavior pediatrician referral
has exact synonym: referral to developmental-behavior pediatrician

Axiom
annotated source: developmental-behavior pediatrician evaluation
annotated property: IAO_0000115
annotated target: An evaluation with a specialist who possesses special skills, training and experience to foster understanding and promotion of optimal development of children and families through research, education, clinical care and advocacy efforts. This physician assists in the prevention, diagnosis and management of developmental difficulties and problematic behaviors in children and in the family dysfunctions that compromise children’s development.
has db xref: abms.org

pediatric endocrinologist evalutation
type: Class
subclass of: pediatrician evaluation
IAO_0000115: An evaluation by a specialist who provides expert care to infants, children and adolescents who have diseases that result from an abnormality in the endocrine glands (glands which secrete hormones). These diseases include diabetes mellitus, growth failure, unusual size for age, early or late pubertal development, birth defects, the genital region and disorders of the thyroid, the adrenal and pituitary glands.
date: 2020-07-09T18:48:58Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by pediatric endocrinologist
has exact synonym: consultation with pediatric endocrinologist
has exact synonym: evaluation by pediatric endocrinologist
has exact synonym: pediatric endocrinologist consultation
has exact synonym: pediatric endocrinologist referral
has exact synonym: referral to pediatric endocrinologist

Axiom
annotated source: pediatric endocrinologist evalutation
annotated property: IAO_0000115
annotated target: An evaluation by a specialist who provides expert care to infants, children and adolescents who have diseases that result from an abnormality in the endocrine glands (glands which secrete hormones). These diseases include diabetes mellitus, growth failure, unusual size for age, early or late pubertal development, birth defects, the genital region and disorders of the thyroid, the adrenal and pituitary glands.
has db xref: abms.org

pediatric cardiologist evaluation
type: Class
subclass of: pediatrician evaluation
IAO_0000115: Evaluation by a specialist who provides comprehensive care to patients with cardiovascular problems. This specialist is skilled in selecting, performing, and evaluating the structural and functional assessment of the heart and blood vessels, and the clinical evaluation of cardiovascular disease.
date: 2020-07-09T18:54:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by pediatric cardiologist
has exact synonym: consultation with pediatric cardiologist
has exact synonym: evaluation by pediatric cardiologist
has exact synonym: pediatric cardiologist consultation
has exact synonym: pediatric cardiologist referral
has exact synonym: referral to pediatric cardiologist

Axiom
annotated source: pediatric cardiologist evaluation
annotated property: IAO_0000115
annotated target: Evaluation by a specialist who provides comprehensive care to patients with cardiovascular problems. This specialist is skilled in selecting, performing, and evaluating the structural and functional assessment of the heart and blood vessels, and the clinical evaluation of cardiovascular disease.
has db xref: abms.org

physiatrist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: Assessment by a specialist who treats patients with disorders or disabilities in the muscles, bones, and nervous system, including neck or back pain, sports and work injuries, stroke, brain injury, spinal cord injury, spasticity, and any other disability or disorder that affects function.
date: 2020-07-09T19:45:07Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009064
has exact synonym: assessment by physiatrist
has exact synonym: assessment by physical medicine and rehabilitation specialist
has exact synonym: consultation by physiatrist
has exact synonym: consultation with physical medicine and rehabilitation specialist
has exact synonym: evaluation by physical medicine and rehabilitation specialist
has exact synonym: examination by physiatrist
has exact synonym: examination by physical mediciane and rehabilitation specialist
has exact synonym: physiatrist assessment
has exact synonym: physiatrist consultation
has exact synonym: physiatrist referral
has exact synonym: physical medicine and rehabilitation specialist assessment
has exact synonym: physical medicine and rehabilitation specialist consultation
has exact synonym: physical medicine and rehabilitation specialist evaluation
has exact synonym: physical medicine and rehabilitation specialist referral
has exact synonym: referral to physiatrist
comment: Treatment modalities by a physiatrist may include medications, injections, therapeutic exercise, electrodiagnosis, and any equipment required for daily activities.

Axiom
annotated source: physiatrist evaluation
annotated property: IAO_0000115
annotated target: Assessment by a specialist who treats patients with disorders or disabilities in the muscles, bones, and nervous system, including neck or back pain, sports and work injuries, stroke, brain injury, spinal cord injury, spasticity, and any other disability or disorder that affects function.
has db xref: abms.org

Axiom
annotated source: physiatrist evaluation
annotated property: comment
annotated target: Treatment modalities by a physiatrist may include medications, injections, therapeutic exercise, electrodiagnosis, and any equipment required for daily activities.
has db xref: abms.org

plastic surgeon evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An assessment with a specialist who focuses on the repair, reconstruction or replacement of physical defects of form or function involving the skin, musculoskeletal system, craniomaxillofacial structures, hand, extremities, breast and trunk and external genitalia or cosmetic enhancement of these areas of the body.
date: 2020-07-09T19:54:01Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: consultation with plastic surgeon
has exact synonym: evaluation by plastic surgeon
has exact synonym: plastic surgeon assessment
has exact synonym: plastic surgeon consultation
has exact synonym: plastic surgeon referral

Axiom
annotated source: plastic surgeon evaluation
annotated property: IAO_0000115
annotated target: An assessment with a specialist who focuses on the repair, reconstruction or replacement of physical defects of form or function involving the skin, musculoskeletal system, craniomaxillofacial structures, hand, extremities, breast and trunk and external genitalia or cosmetic enhancement of these areas of the body.
has db xref: abms.org

psychiatrist evaluation
type: Class
subclass of: psychiatry and neurology specialist evaluation
IAO_0000115: Evaluation by a physician who specializes in the evaluation and treatment of mental, addictive and emotional disorders.
date: 2020-07-09T20:37:35Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009066
has exact synonym: assessment by psychiatrist
has exact synonym: consult with psychiatrist
has exact synonym: evaluation by psychiatrist
has exact synonym: psychiatric examination
has exact synonym: psychiatrist assessment
has exact synonym: psychiatrist consultation
has exact synonym: psychiatrist referral
has exact synonym: referral to psychiatrist

Axiom
annotated source: psychiatrist evaluation
annotated property: IAO_0000115
annotated target: Evaluation by a physician who specializes in the evaluation and treatment of mental, addictive and emotional disorders.
has db xref: abms.org

child and adolescent psychiatrist evaluation
type: Class
subclass of: psychiatrist evaluation
IAO_0000115: Evaluation by a physician who specializes in the evaluation and treatment of mental, addictive and emotional disorders in children and adolescence.
date: 2020-07-09T20:41:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by child and adolescent psychiatrist
has exact synonym: assessment by child psychiatrist
has exact synonym: child and adolescent psychiatrist assessment
has exact synonym: child and adolescent psychiatrist consultation
has exact synonym: child and adolescent psychiatrist referral
has exact synonym: child psychiatrist assessment
has exact synonym: child psychiatrist evaluation
has exact synonym: child psychiatrist referral
has exact synonym: consultation with child and adolescent psychiatrist
has exact synonym: consultation with child psychiatrist
has exact synonym: evaluation by child and adolescent psychiatrist
has exact synonym: referral to child and adolescent psychiatrist
has exact synonym: referral to child psychiatrist

Axiom
annotated source: child and adolescent psychiatrist evaluation
annotated property: IAO_0000115
annotated target: Evaluation by a physician who specializes in the evaluation and treatment of mental, addictive and emotional disorders in children and adolescence.
has db xref: abms.org

neurologist evaluation
type: Class
subclass of: psychiatry and neurology specialist evaluation
IAO_0000115: An evaluation a specialist who treats all types of disease or impaired function of the brain, spinal cord, peripheral nerves, muscles and autonomic nervous system, as well as the blood vessels that relate to these structures.
date: 2020-07-10T16:33:00Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009058
has exact synonym: consultation with neurologist
has exact synonym: neurologist assessment
has exact synonym: neurologist consultation
has exact synonym: neurologist referral
has exact synonym: referral to neurologist

Axiom
annotated source: neurologist evaluation
annotated property: IAO_0000115
annotated target: An evaluation a specialist who treats all types of disease or impaired function of the brain, spinal cord, peripheral nerves, muscles and autonomic nervous system, as well as the blood vessels that relate to these structures.
has db xref: abms.org

child neurologist evaluation
type: Class
subclass of: neurologist evaluation
IAO_0000115: Evaluation with a specialist who diagnose and treat all types of disease or impaired function of the brain, spinal cord, peripheral nerves, muscles and autonomic nervous system, as well as the blood vessels that relate to these structures in infants, children, and adolescents. They also have special competence in genetic and metabolic problems, malformation, retardation and other neurodevelopmental problems of childhood.
date: 2020-07-10T18:35:13Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by pediatric neurologist
has exact synonym: child neurologist assessment
has exact synonym: child neurologist consultation
has exact synonym: consultation with child neurologist
has exact synonym: consultation with pediatric neurologist
has exact synonym: evaluation by child neurologist
has exact synonym: pediatric neurologist assessment
has exact synonym: pediatric neurologist consultation
has exact synonym: pediatric neurologist evaluation
has exact synonym: referral to child neurologist
has exact synonym: referral to pediatric neurologist

Axiom
annotated source: child neurologist evaluation
annotated property: IAO_0000115
annotated target: Evaluation with a specialist who diagnose and treat all types of disease or impaired function of the brain, spinal cord, peripheral nerves, muscles and autonomic nervous system, as well as the blood vessels that relate to these structures in infants, children, and adolescents. They also have special competence in genetic and metabolic problems, malformation, retardation and other neurodevelopmental problems of childhood.
has db xref: abms.org

radiologist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: Evaluation by a specialist who uses imaging methodologies to diagnose and manage patients and provide therapeutic options.
date: 2020-07-10T19:06:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by radiologist
has exact synonym: evaluation by radiologist
has exact synonym: radiologist assessment

Axiom
annotated source: radiologist evaluation
annotated property: IAO_0000115
annotated target: Evaluation by a specialist who uses imaging methodologies to diagnose and manage patients and provide therapeutic options.
has db xref: abms.org

general surgeon evaluation
type: Class
subclass of: surgeon evaluation
IAO_0000115: Evaluation by an expert in the diagnosis and care of patients with diseases and disorders affecting the abdomen, digestive tract, endocrine system, breast, skin and blood vessels. A general surgeon is also trained in the treatment of patients who are injured or critically ill, and in the care of pediatric and cancer patients. General surgeons are skilled in the use of minimally invasive techniques and endoscopies.
date: 2020-07-10T19:33:25Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by general surgeon
has exact synonym: consultation with general surgeon
has exact synonym: evaluation by general surgeon
has exact synonym: general surgeon assessment
has exact synonym: general surgeon consultation
has exact synonym: general surgeon evaluation

Axiom
annotated source: general surgeon evaluation
annotated property: IAO_0000115
annotated target: Evaluation by an expert in the diagnosis and care of patients with diseases and disorders affecting the abdomen, digestive tract, endocrine system, breast, skin and blood vessels. A general surgeon is also trained in the treatment of patients who are injured or critically ill, and in the care of pediatric and cancer patients. General surgeons are skilled in the use of minimally invasive techniques and endoscopies.
has db xref: abms.org

vascular surgeon evaluation
type: Class
subclass of: surgeon evaluation
IAO_0000115: An evaluation by a specialist who performs preoperative, operative, and postoperative management of patients with disorders of the arterial, venous and lymphatic systems, excluding vessels of the brain and the heart.
date: 2020-07-10T19:54:59Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by vascular surgeon
has exact synonym: evaluation by vascular surgeon
has exact synonym: referral by vascular surgeon
has exact synonym: vascular surgeon assessment
has exact synonym: vascular surgeon consultation
has exact synonym: vascular surgeon referral

thoracic and cardiac surgeon evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: Evaluation by a specialist who focuses on the operative, perioperative, and surgical critical care of patients with acquired and congenital pathologic conditions within the chest.
date: 2020-07-10T20:40:44Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment by thoracic and cardiac surgeon
has exact synonym: assessment by thoracic surgeon
has exact synonym: consultation with thoracic and cardiac surgeon
has exact synonym: consultation with thoracic surgeon
has exact synonym: evaluation by thoracic and cardiac surgeon
has exact synonym: evaluation by thoracic surgeon
has exact synonym: referral to thoracic and cardiac surgeon
has exact synonym: referral to thoracic surgeon
has exact synonym: thoracic and cardiac surgeon assessment
has exact synonym: thoracic and cardiac surgeon consultation
has exact synonym: thoracic and cardiac surgeon referral
has exact synonym: thoracic surgeon assessment
has exact synonym: thoracic surgeon evaluation
has exact synonym: thoracic surgeon referral

Axiom
annotated source: thoracic and cardiac surgeon evaluation
annotated property: IAO_0000115
annotated target: Evaluation by a specialist who focuses on the operative, perioperative, and surgical critical care of patients with acquired and congenital pathologic conditions within the chest.
has db xref: abms.org

urologist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: An evaluation by a specialist that focuses on diagnosing and treating disorders of the urinary tracts of males and females, and on the reproductive system of males. This specialist manages non-surgical problems such as urinary tract infections and benign prostatic hyperplasia, as well as surgical problems such as the surgical management of cancers, the correction of congenital abnormalities, and correcting stress incontinence.
date: 2020-07-10T20:44:20Z
creator: http://orcid.org/0000-0001-7941-2961
has alternative id: MAXO:0009067
has exact synonym: assessment by genitourinary surgeon
has exact synonym: assessment by urologist
has exact synonym: consultation with genitourinary surgeon
has exact synonym: consultation with urologist
has exact synonym: evaluation by genitourinary surgeon
has exact synonym: evaluation by urologist
has exact synonym: examination by urologist
has exact synonym: genitourinary surgeon consultation
has exact synonym: genitourinary surgeon evaluation
has exact synonym: referral to genitourinary surgeon
has exact synonym: referral to urologist
has exact synonym: urologist assessment
has exact synonym: urologist consultation
has exact synonym: urologist referral

Axiom
annotated source: urologist evaluation
annotated property: IAO_0000115
annotated target: An evaluation by a specialist that focuses on diagnosing and treating disorders of the urinary tracts of males and females, and on the reproductive system of males. This specialist manages non-surgical problems such as urinary tract infections and benign prostatic hyperplasia, as well as surgical problems such as the surgical management of cancers, the correction of congenital abnormalities, and correcting stress incontinence.
has db xref: abms.org

psychiatry and neurology specialist evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: Evaluation by a physician who specializes in the evaluation and treatment of of the brain.
date: 2020-07-13T17:01:27Z
creator: http://orcid.org/0000-0001-7941-2961

surgeon evaluation
type: Class
subclass of: medical specialist evaluation
IAO_0000115: Assessment by a specialist who has expertise in the diagnosis and preoperative, operative, and postoperative management of patient care.
date: 2020-07-13T17:57:48Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: surgeon evaluation
annotated property: IAO_0000115
annotated target: Assessment by a specialist who has expertise in the diagnosis and preoperative, operative, and postoperative management of patient care.
has db xref: abms.org

hysterosonography
type: Class
subclass of: MAXO_0010201
IAO_0000115: A procedure, also known as sonohysterography or saline infusion sonography, using a minimally invasive ultrasound technique to view the inside of the uterus. Sterile saline is injected into the endometrial cavity thereby distending the endometrial cavity, providing good visualization of the anatomic structures within.
date: 2020-07-16T14:18:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38066
has exact synonym: diagnostic hysterosonography
has exact synonym: medical hysterosonography
has exact synonym: sonohysterography
has narrow synonym: saline infusion sonography

Axiom
annotated source: hysterosonography
annotated property: IAO_0000115
annotated target: A procedure, also known as sonohysterography or saline infusion sonography, using a minimally invasive ultrasound technique to view the inside of the uterus. Sterile saline is injected into the endometrial cavity thereby distending the endometrial cavity, providing good visualization of the anatomic structures within.
has db xref: NCIT:C38066

intravascular ultrasonography
type: Class
subclass of: ultrasonography procedure
IAO_0000115: An invasive procedure in which sound waves (called ultrasound) are bounced off of vascular tissues from within the vessel and the echoes produce a picture (sonogram).
date: 2020-07-16T14:31:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C99535
has exact synonym: IVUS
has exact synonym: diagnostic intravascular ultrasound
has exact synonym: intravascular sonography
has exact synonym: intravascular ultrasound
has exact synonym: medical intravascular ultrasonography

Axiom
annotated source: intravascular ultrasonography
annotated property: IAO_0000115
annotated target: An invasive procedure in which sound waves (called ultrasound) are bounced off of vascular tissues from within the vessel and the echoes produce a picture (sonogram).
has db xref: NCIT:C99535

Axiom
annotated source: intravascular ultrasonography
annotated property: hasExactSynonym
annotated target: IVUS
has synonym type: OMO_0003000

transvaginal ultrasonography
type: Class
subclass of: MAXO_0010216
IAO_0000115: A technique in which sound waves are sent out by an ultrasound probe that has been inserted in the vagina and a computer uses the ultrasound echoes to create an image of the female genital tract. The test can be performed to evaluate women with infertility problems, abnormal bleeding, sources of unexplained pain, congenital malformations of the uterus and ovaries, and possible tumors and infection.
date: 2020-07-16T14:38:38Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17644
has exact synonym: TVS
has exact synonym: TVU
has exact synonym: diagnostic transvaginal ultrasound
has exact synonym: medical transvaginal sonography
has exact synonym: transvaginal sonography
has exact synonym: transvaginal ultrasound
has exact synonym: transvaginal ultrasound examination

Axiom
annotated source: transvaginal ultrasonography
annotated property: IAO_0000115
annotated target: A technique in which sound waves are sent out by an ultrasound probe that has been inserted in the vagina and a computer uses the ultrasound echoes to create an image of the female genital tract. The test can be performed to evaluate women with infertility problems, abnormal bleeding, sources of unexplained pain, congenital malformations of the uterus and ovaries, and possible tumors and infection.
has db xref: NCIT:C17644

Axiom
annotated source: transvaginal ultrasonography
annotated property: hasExactSynonym
annotated target: TVS
has synonym type: OMO_0003000

Axiom
annotated source: transvaginal ultrasonography
annotated property: hasExactSynonym
annotated target: TVU
has synonym type: OMO_0003000

transrectal ultrasonography
type: Class
subclass of: MAXO_0010210
IAO_0000115: A procedure that uses sound waves to create a video image of the pelvic organs and tissues. A small, lubricated probe placed into the rectum releases sound waves, which create echoes as they enter a pelvic organ. The echoes that bounce back are sent to a computer that translates the pattern of echoes into a picture of the specific organ under examination. This procedure is most often used to evaluate the prostate gland.
date: 2020-07-16T14:46:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C18315
has exact synonym: ERUS
has exact synonym: TRUS
has exact synonym: diagnostic transrectal ultrasound
has exact synonym: endorectal sonography
has exact synonym: endorectal ultrasound
has exact synonym: endorectal ultrsonography
has exact synonym: medical transrectal ultrasound
has exact synonym: transrectal sonography
has exact synonym: transrectal ultrasound
has exact synonym: transrectal ultrasound examination

Axiom
annotated source: transrectal ultrasonography
annotated property: IAO_0000115
annotated target: A procedure that uses sound waves to create a video image of the pelvic organs and tissues. A small, lubricated probe placed into the rectum releases sound waves, which create echoes as they enter a pelvic organ. The echoes that bounce back are sent to a computer that translates the pattern of echoes into a picture of the specific organ under examination. This procedure is most often used to evaluate the prostate gland.
has db xref: NCIT:C18315

Axiom
annotated source: transrectal ultrasonography
annotated property: hasExactSynonym
annotated target: ERUS
has synonym type: OMO_0003000

Axiom
annotated source: transrectal ultrasonography
annotated property: hasExactSynonym
annotated target: TRUS
has synonym type: OMO_0003000

allied health professional evaluation
type: Class
subclass of: medical professional evaluation
IAO_0000115: A procedure where a allied health care provider who was not previously involved in a patient's treatment, reviews a patient's medical history, examines the patient, and makes recommendations as to care and treatment. This is care provided by health care practitioners who are distinct providers from dentistry, nursing, medicine, and pharmacy health care professionals.
date: 2020-10-06T17:59:44Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: allied health clnicians support
has exact synonym: allied health practitioner consultation
has exact synonym: allied health practitioner evaluation
has exact synonym: allied health professional consultation
has exact synonym: assessment by allied health professional
has exact synonym: consulationat with allied health professional
has exact synonym: consultation with allied health practitioner
has exact synonym: evaluation by allied health professional
has exact synonym: evaluation managed by allied health professional
has exact synonym: support by allied health clinicians

occupational therapist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial evaluation or assessment by a health professional trained to help people who are ill or disabled learn to manage their daily activities.
date: 2020-10-06T19:51:46Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: OT assessment
has exact synonym: OT consult
has exact synonym: OT eval
has exact synonym: OT evaluation
has exact synonym: OT treatment
has exact synonym: assessment by occupational therapist
has exact synonym: evaluation by occupational therapist
has exact synonym: managed by occupational therapist
has exact synonym: occupational therapist assessment
has exact synonym: occupational therapist consultation
has exact synonym: occupational therapist management
has exact synonym: occupational therapist treatment
has exact synonym: treatment by OT
has exact synonym: treatment by occupational therapist

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: OT assessment
has synonym type: OMO_0003000

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: OT consult
has synonym type: OMO_0003000

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: OT eval
has synonym type: OMO_0003000

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: OT evaluation
has synonym type: OMO_0003000

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: OT treatment
has synonym type: OMO_0003000

Axiom
annotated source: occupational therapist evaluation
annotated property: hasExactSynonym
annotated target: treatment by OT
has synonym type: OMO_0003000

speech-language pathologist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial assessment by a professional who works to prevent, assess, diagnose, and treat speech, language, social communication, congnitive-communication, and swallowing disorders.
date: 2020-10-08T15:24:36Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessment with speech therapist
has exact synonym: consult with speech therapist
has exact synonym: evaluation by speech and language therapist
has exact synonym: speech and language pathologist evaluation
has exact synonym: speech and language therapist evaluation
has exact synonym: speech therapist assessment
has exact synonym: speech therapist consultation
has exact synonym: speech therapist evaluation
has exact synonym: speech-language pathologist assessment
has exact synonym: speech-language pathologist examination
has exact synonym: speech/language pathologist evaluation
has exact synonym: speech/language therapist evaluation

Axiom
annotated source: speech-language pathologist evaluation
annotated property: IAO_0000115
annotated target: An initial assessment by a professional who works to prevent, assess, diagnose, and treat speech, language, social communication, congnitive-communication, and swallowing disorders.
has db xref: asha.org

audiologist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: A first assessment by a trained non-medical health professional who specializes in the identification, testing, habilitation and rehabilitation of hearing loss and other auditory and balance disorders. Particularly, an audiologist may be involved in diagnostic and screening procedures to determine hearing deficits, as well as in assessment of amplification devices and instruction in their care, training in speechreading, and may serve as consultant to government and industry on issues concerning environmental, noise-induced hearing loss.
date: 2020-10-08T20:20:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51804
has exact synonym: assessment by audiologist
has exact synonym: audilogic assessment
has exact synonym: audiologic evaluation
has exact synonym: audiology evaluation
has exact synonym: audiology examination
has exact synonym: evaluation by audiologist
has exact synonym: treatment by audiologist

fibrate antilipidemic agent therapy
type: Class
subclass of: dyslipidemic agent therapy
IAO_0000115: A therapy derived from fibric acid that lowers serum LDL cholesterol levels by activating peroxisome proliferator activated receptor alpha (PPARa).
date: 2020-11-17T21:12:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C98150
has exact synonym: fibrate dyslipidemic agent therapy

bile acid sequestrant therapy
type: Class
subclass of: dyslipidemic agent therapy
IAO_0000115: Therapy using a highly charged polymeric agent to bind bile acids in the gastrointestinal tract and prevent their reabsorption from the gut. The bound bile acids are excreted with the feces and plasma cholesterol is converted to bile acid to reestablish normal bile acid levels, resulting in a lowering of plasma cholesterol concentrations.
date: 2020-11-17T21:21:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: bile-acid sequestrant agent therapy
has exact synonym: bile-acid sequestrant therapy
has exact synonym: treatment with bile-acid sequestrant

HMG-CoA reductase inhibitor therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35664
subclass of: dyslipidemic agent therapy
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35664
IAO_0000115: Therapy that inhibits HMG-CoA reductase inhibitor.
date: 2020-11-17T21:37:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hydroxymethylglutaryl-CoA reductase inhibitor therapy
has exact synonym: statin agent therapy
has exact synonym: treatment with EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
has exact synonym: treatment with statins

nicotinic acid agent therapy
type: Class
subclass of: dyslipidemic agent therapy
IAO_0000115: Treatment with an agent that works through, or mimics, the action of niacin.
date: 2020-11-17T21:45:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:15940
has db xref: NCIT:C98151
has narrow synonym: niacin-based antilipidemic agent
has related synonym: niacin agent therapy
has related synonym: treatment with niacin
comment: An antilipidemic agent that works through, or mimics, the action of niacin to increase HDL-C levels by blocking hepatic uptake of apolipoprotein A-1 and decreasing HDL clearance. The use of free niacin is limited by its side effects of skin flushing (i.e., redness, itching, burning, and paresthesias)

Axiom
annotated source: nicotinic acid agent therapy
annotated property: comment
annotated target: An antilipidemic agent that works through, or mimics, the action of niacin to increase HDL-C levels by blocking hepatic uptake of apolipoprotein A-1 and decreasing HDL clearance. The use of free niacin is limited by its side effects of skin flushing (i.e., redness, itching, burning, and paresthesias)
has db xref: NCIT:C98151

potassium-sparing diuretic agent therapy
type: Class
subclass of: diuretic agent therapy
IAO_0000115: Treatment with a diuretic agent that produces diuresis without increasing potassium excretion.
date: 2020-11-18T16:10:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49186
has exact synonym: treatment with potassium-sparing diuretic
comment: Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.

Axiom
annotated source: potassium-sparing diuretic agent therapy
annotated property: comment
annotated target: Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.
has db xref: NCIT:C49186

thiazide diuretic agent therapy
type: Class
subclass of: diuretic agent therapy
IAO_0000115: Treatment with a benzothiadiazide derivative or other thiazide-like agent with diuretic and anti-hypertensive activity.
date: 2020-11-18T16:16:04Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C49185
has exact synonym: treatment with thiazide diuretic agent
comment: Thiazide diuretics inhibit the sodium-chloride transporter in the distal tubule in the kidneys, thereby suppressing sodium and chloride reabsorption from the distal convoluted tubules (DCT) and increasing the excretion of sodium, chloride, potassium and water. In addition, thiazide diuretics decrease excretion of calcium and uric acid. These agents cause vasodilation possibly by activating calcium-activated potassium channels in vascular smooth muscle and inhibiting various carbonic anhydrases in vascular tissue.

Axiom
annotated source: thiazide diuretic agent therapy
annotated property: comment
annotated target: Thiazide diuretics inhibit the sodium-chloride transporter in the distal tubule in the kidneys, thereby suppressing sodium and chloride reabsorption from the distal convoluted tubules (DCT) and increasing the excretion of sodium, chloride, potassium and water. In addition, thiazide diuretics decrease excretion of calcium and uric acid. These agents cause vasodilation possibly by activating calcium-activated potassium channels in vascular smooth muscle and inhibiting various carbonic anhydrases in vascular tissue.
has db xref: NCIT:C49185

sulfonylurea agent therapy
type: Class
subclass of: hypoglycemic drug therapy
IAO_0000115: Treatment with sulfonamide urea derivatives with antihyperglycemic activity.
date: 2020-11-18T16:22:03Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C97936
has exact synonym: sulfonylurea antidiabetic agent therapy
has exact synonym: treatment with sulfonylurea
has exact synonym: treatment with sulfonylurea agent
comment: Sulphonylurea antidiabetic agents bind to sulfonylurea receptor type 1 (SUR1), the subunit of ATP-sensitive inwardly-rectifier potassium (IKATP) channels on the membranes of pancreatic beta cells, thereby blocking the inward current flow (influx) of positively charged K+ ions into the cell. This results in tonic membrane depolarization, and induces a calcium ion influx through voltage-sensitive calcium channels; increased intracellular calcium ion levels trigger exocytosis of insulin-containing granules. This eventually induces secretion of insulin. The IKATP channels found in pancreatic islets are complexes of four IKATP 6.2 and four SUR1 subunits. In addition, some sulfonylureas of larger molecular size may increase the sensitivity of peripheral tissues to insulin mediated through peroxisome proliferator-activated receptor gamma (PPARgamma).

Axiom
annotated source: sulfonylurea agent therapy
annotated property: comment
annotated target: Sulphonylurea antidiabetic agents bind to sulfonylurea receptor type 1 (SUR1), the subunit of ATP-sensitive inwardly-rectifier potassium (IKATP) channels on the membranes of pancreatic beta cells, thereby blocking the inward current flow (influx) of positively charged K+ ions into the cell. This results in tonic membrane depolarization, and induces a calcium ion influx through voltage-sensitive calcium channels; increased intracellular calcium ion levels trigger exocytosis of insulin-containing granules. This eventually induces secretion of insulin. The IKATP channels found in pancreatic islets are complexes of four IKATP 6.2 and four SUR1 subunits. In addition, some sulfonylureas of larger molecular size may increase the sensitivity of peripheral tissues to insulin mediated through peroxisome proliferator-activated receptor gamma (PPARgamma).
has db xref: NCIT:C97936

menopausal hormone therapy
type: Class
subclass of: sex hormone modifying agent therapy
IAO_0000115: Treatment with estrogens or estrogen/progesterone after menopause or ovariectomy to prevent pathological effects of decreased estrogen production.
date: 2020-11-19T16:03:14Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: MHT
has exact synonym: menopausal hormone replacement therapy
has exact synonym: postmenopausal hormone therapy

Axiom
annotated source: menopausal hormone therapy
annotated property: IAO_0000115
annotated target: Treatment with estrogens or estrogen/progesterone after menopause or ovariectomy to prevent pathological effects of decreased estrogen production.
has db xref: NCIT:C15599

cytogenetic analysis
type: Class
subclass of: molecular genetic testing
IAO_0000115: Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases and abnormalities.
date: 2020-11-19T19:13:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C18280
has exact synonym: chromosome analysis
has exact synonym: cytogenetic study
has exact synonym: cytogenetic testing

Axiom
annotated source: cytogenetic analysis
annotated property: IAO_0000115
annotated target: Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases and abnormalities.
has db xref: NCIT:C18280

chromosomal breakage analysis
type: Class
subclass of: cytogenetic analysis
IAO_0000115: A test to detect chromosomal breakage or aberrations (breaks, gaps, rearrangements, radials, exchanges, endoreduplications) in peripheral blood cells after culture with a T-cell mitogen and a DNA clastogenic (cross-linking) agent, such as diepoxybutane (DEB) or mitomycin C (MMC).
date: 2020-11-19T19:24:16Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Chromosome Breakage Analysis (DEB/MMC)
has exact synonym: DEB/MMC testing
has exact synonym: chromosomal breakage testing
has exact synonym: induced chormosomal breakage testing

Axiom
annotated source: chromosomal breakage analysis
annotated property: IAO_0000115
annotated target: A test to detect chromosomal breakage or aberrations (breaks, gaps, rearrangements, radials, exchanges, endoreduplications) in peripheral blood cells after culture with a T-cell mitogen and a DNA clastogenic (cross-linking) agent, such as diepoxybutane (DEB) or mitomycin C (MMC).
has db xref: PMID:25006279

hematopoietic stem cell transplantation
type: Class
subclass of: transplantation procedure
IAO_0000115: Transfer of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood into the body.
date: 2020-11-19T19:56:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: HPSCT
has exact synonym: HSCT

Axiom
annotated source: hematopoietic stem cell transplantation
annotated property: hasExactSynonym
annotated target: HPSCT
has synonym type: OMO_0003000

Axiom
annotated source: hematopoietic stem cell transplantation
annotated property: hasExactSynonym
annotated target: HSCT
has synonym type: OMO_0003000

fecal microbiota transplantation
type: Class
subclass of: transplantation procedure
IAO_0000115: The transplantation of fecal bacteria, via enema, colonoscopy, or other method, from a healthy individual to a recipient.
date: 2020-11-19T20:03:04Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: FMT
has exact synonym: fecal material transplantation
has exact synonym: fecal transplantation
has exact synonym: stool transplantation

Axiom
annotated source: fecal microbiota transplantation
annotated property: IAO_0000115
annotated target: The transplantation of fecal bacteria, via enema, colonoscopy, or other method, from a healthy individual to a recipient.
has db xref: NCIT:C118643

Axiom
annotated source: fecal microbiota transplantation
annotated property: hasExactSynonym
annotated target: FMT
has synonym type: OMO_0003000

T cell-depleted hematopoietic stem cell transplantation
type: Class
subclass of: hematopoietic stem cell transplantation
IAO_0000115: The removal of T-cells from the donor's hematopoietic stem cell specimen prior to its transfusion into the recipient.
date: 2020-11-19T20:07:15Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116468

Axiom
annotated source: T cell-depleted hematopoietic stem cell transplantation
annotated property: IAO_0000115
annotated target: The removal of T-cells from the donor's hematopoietic stem cell specimen prior to its transfusion into the recipient.
has db xref: NCIT:C116468

transplant conditioning
type: Class
subclass of: chemotherapy
IAO_0000115: Administration of high doses of chemotherapy or radiation therapy, as well as immunosuppressive therapy, to a transplant recipient prior to a bone marrow or hematopoietic stem cell transplant. Conditioning destroys the patient's abnormal blood cells or cancer, as well as slows the patient's immune response against the donor bone marrow (graft rejection).
date: 2020-11-19T20:12:40Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64468
has exact synonym: conditioning regimen

Axiom
annotated source: transplant conditioning
annotated property: IAO_0000115
annotated target: Administration of high doses of chemotherapy or radiation therapy, as well as immunosuppressive therapy, to a transplant recipient prior to a bone marrow or hematopoietic stem cell transplant. Conditioning destroys the patient's abnormal blood cells or cancer, as well as slows the patient's immune response against the donor bone marrow (graft rejection).
has db xref: NCIT:C64468

clinical surveilance
type: Class
subclass of: disease screening
IAO_0000115: The systematic collection, analysis, and interpretation of health data on an ongoing basis.
date: 2020-11-19T20:25:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15719

Axiom
annotated source: clinical surveilance
annotated property: IAO_0000115
annotated target: The systematic collection, analysis, and interpretation of health data on an ongoing basis.
has db xref: NCIT:C15719

bone marrow aspiration
type: Class
subclass of: biopsy of bone marrow
IAO_0000115: Removal of a small amount of liquid bone marrow through a needle.
date: 2020-11-19T20:31:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: bone marrow aspiration procedure

bone marrow examination
type: Class
subclass of: clinical cytological testing
IAO_0000115: The pathologic analysis of samples of bone marrow obtained by bone marrow biopsy and bone marrow aspiration.
date: 2020-11-19T20:33:41Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: bone marrow testing
has narrow synonym: bone marrow monitoring

cellularity measurement
type: Class
subclass of: cell measurement
subclass of: clinical cytological testing
IAO_0000115: The determination of the amount of degree, quality or condition of cells present in a sample.
date: 2020-11-19T20:39:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C111153
has exact synonym: cellularity grade measurement
has exact synonym: cellularity indexing

Axiom
annotated source: cellularity measurement
annotated property: IAO_0000115
annotated target: The determination of the amount of degree, quality or condition of cells present in a sample.
has db xref: NCIT:C111153

liquid biopsy
type: Class
subclass of: cancer screening
subclass of: clinical biopsy
IAO_0000115: The sampling and analysis of non-solid biological tissue often through rapid and non-invasive methods, which allows the assessment in real-time of the evolving landscape of cancer.
date: 2020-11-19T20:45:40Z
creator: http://orcid.org/0000-0001-7941-2961
has related synonym: solid tumor monitoring

Axiom
annotated source: liquid biopsy
annotated property: IAO_0000115
annotated target: The sampling and analysis of non-solid biological tissue often through rapid and non-invasive methods, which allows the assessment in real-time of the evolving landscape of cancer.
has db xref: PMID:32580740

blood transfusion
type: Class
subclass of: transplantation procedure
subclass of: infusion procedure
IAO_0000115: The injection of whole blood or a blood component directly into the bloodstream.
date: 2020-11-19T20:58:55Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: transfusion
has db xref: NCIT:C15192
has db xref: OGMS:0000145
has exact synonym: transfusion of blood products
has narrow synonym: blood component transfusion

Axiom
annotated source: blood transfusion
annotated property: IAO_0000115
annotated target: The injection of whole blood or a blood component directly into the bloodstream.
has db xref: NCIT:C15192

infusion procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: Any form of treatment that is introduced into the body via a blood vessel, a muscle, or the spinal cord.
date: 2020-11-19T21:01:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15388
has exact synonym: infusion

Axiom
annotated source: infusion procedure
annotated property: IAO_0000115
annotated target: Any form of treatment that is introduced into the body via a blood vessel, a muscle, or the spinal cord.
has db xref: NCIT:C15388

avoid unprotected sexual intercourse
type: Class
subclass of: cognitive and behavioral intervention avoidance
IAO_0000115: Avoid sexual intercourse without the use of precautions to prevent conception or the transmission of sexually transmitted diseases.
date: 2020-11-19T21:20:20Z
creator: http://orcid.org/0000-0001-7941-2961

human papillomavirus vaccination
type: Class
subclass of: vaccination
IAO_0000115: Vaccination against human papillomavirus infection.
date: 2020-11-19T21:22:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: VO:0000667
has exact synonym: HPV vaccination

vitamin B12 supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176843
subclass of: B vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176843
IAO_0000115: Addition of vitamin B12 to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of vitamin B12
has exact synonym: supplementation of vitamin B12
has exact synonym: vitamin B12 supplemental intake

B vitamin supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_75769
subclass of: water-soluble supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_75769
IAO_0000115: Addition of B vitamin to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-08-25T09:00:01Z
has exact synonym: B vitamin supplemental intake
has exact synonym: dietary supplementation of B vitamin
has exact synonym: supplementation of B vitamin

parenteral nutrition intake
type: Class
subclass of: nutrition intake
IAO_0000115: Intake of nutrients intravenously.
date: 2020-11-30T16:40:53Z
creator: http://orcid.org/0000-0001-7941-2961

partial parenteral nutrition intake
type: Class
subclass of: parenteral nutrition intake
IAO_0000115: Intake of nutrients intravenously as well as enterically.
date: 2020-11-30T16:43:26Z
creator: http://orcid.org/0000-0001-7941-2961

peripheral parenteral nutrition intake
type: Class
subclass of: parenteral nutrition intake
IAO_0000115: Intravenous nutrition intake administered via vein access in a limb.
date: 2020-11-30T16:45:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: PPN intake

central venous nutrition intake
type: Class
subclass of: parenteral nutrition intake
IAO_0000115: Intravenous nutrition administration via the central vein.
date: 2020-11-30T16:46:01Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: CVN intake

low fat diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: A recommendation to alter dietary intake where 30% or less of the calories come from fat.
date: 2020-11-30T17:13:24Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCBIBook:NBK553097

prescriptive dietary intake
type: Class
subclass of: dietary intervention
IAO_0000115: Recommendation of a specific diet to adhere to prevent, relieve, or alleviate symptoms.
date: 2020-11-30T17:15:20Z
creator: http://orcid.org/0000-0001-7941-2961

small meal size recommendation
type: Class
subclass of: nutrition intake
IAO_0000115: A recommendation to alter a standard diet from 2-3 large meals per day to many frequent smaller meals throughout the day.
date: 2020-11-30T17:19:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: frequent small meals recommendation

prescriptive vegetarian diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: A recommendation to maintain a vegetarian diet for health reasons.
date: 2020-11-30T17:26:23Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: vegetarian diet intake

carbohydrate controlled diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: Dietary recommendation to closely control the amount of carbohydrates consumed.
date: 2020-11-30T17:38:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCBIBook:NBK537084
comment: Very low-carbohydrate (< 10% carbohydrates) or 20-50 gm/day Low-carbohydrate (<26% carbohydrates) or less than < 130 gm/day Moderate-carbohydrate (26%-44%) High-carbohydrate (45% or greater)

Axiom
annotated source: carbohydrate controlled diet intake
annotated property: comment
annotated target: Very low-carbohydrate (< 10% carbohydrates) or 20-50 gm/day Low-carbohydrate (<26% carbohydrates) or less than < 130 gm/day Moderate-carbohydrate (26%-44%) High-carbohydrate (45% or greater)
has db xref: NCBIBook:NBK537084

carbohydrate-restricted diet intake
type: Class
subclass of: carbohydrate controlled diet intake
IAO_0000115: A dietary recommendation to restrict the amount of carbohydrates consumed.
date: 2020-11-30T17:41:20Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: carbohydrate restrictive diet intake
has exact synonym: low carbohydrate diet intake

low purine diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: A recommendation to consume food low in purine content.
date: 2020-11-30T17:50:25Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: low intake of purine-rich diet
has exact synonym: low intake of purine-rich food
has exact synonym: purine restrictive diet intake

DASH diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: A recommendation to adhere to Dietary Approaches to Stop Hypertension (DASH) diet. The diet promotes consumption of vegetables and fruits, lean meat and dairy products, and the inclusion of micronutrients and the reduction of sodium in the diet to about 1500 mg/day.
date: 2020-11-30T18:26:25Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: dietary approaches to stop hypertension diet intake

Axiom
annotated source: DASH diet intake
annotated property: IAO_0000115
annotated target: A recommendation to adhere to Dietary Approaches to Stop Hypertension (DASH) diet. The diet promotes consumption of vegetables and fruits, lean meat and dairy products, and the inclusion of micronutrients and the reduction of sodium in the diet to about 1500 mg/day.
has db xref: NCBIBook:NBK482514

exclusive formula feeding
type: Class
subclass of: dietary intervention
IAO_0000115: Exclusively feeding an infant formula in efforts to prevent allergic reactions, intolerances, or communication of diseases (i.e. HIV) through feeding human milk.
date: 2020-11-30T18:51:35Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: EFF

Axiom
annotated source: exclusive formula feeding
annotated property: IAO_0000115
annotated target: Exclusively feeding an infant formula in efforts to prevent allergic reactions, intolerances, or communication of diseases (i.e. HIV) through feeding human milk.
has db xref: PMID:23711175

Axiom
annotated source: exclusive formula feeding
annotated property: hasExactSynonym
annotated target: EFF
has synonym type: OMO_0003000

low FODMAP diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: A diet low in poorly absorbed, fermentable, short chain carbohydrates including fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) intended to reduce bloating, abdominal pain, excessive flatus and altered bowel habit.
date: 2020-11-30T19:48:31Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: low FODMAP diet intake
annotated property: IAO_0000115
annotated target: A diet low in poorly absorbed, fermentable, short chain carbohydrates including fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) intended to reduce bloating, abdominal pain, excessive flatus and altered bowel habit.
has db xref: PMID:28244669

ferrous sulfate supplementation
type: Class
subclass of: iron supplementation
IAO_0000115: Addition of iron to the diet by taking ferrous sulfate supplements.
date: 2020-12-07T19:35:36Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: slow release iron supplementation

liver function testing
type: Class
subclass of: digestive system testing
IAO_0000115: The quantitative measurement of liver enzymes in the blood, which is useful in assessing the functional state of a patient's liver. Liver function tests include the measurement of albumin, alanine transaminase, aspartate transaminase, alkaline phosphatase, bilirubin, and gamma glutamyl transferase.
date: 2019-01-15T19:35:59Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74954
has exact synonym: LFT
has exact synonym: liver function assessment

Axiom
annotated source: liver function testing
annotated property: IAO_0000115
annotated target: The quantitative measurement of liver enzymes in the blood, which is useful in assessing the functional state of a patient's liver. Liver function tests include the measurement of albumin, alanine transaminase, aspartate transaminase, alkaline phosphatase, bilirubin, and gamma glutamyl transferase.
has db xref: NCIT:C74954

Axiom
annotated source: liver function testing
annotated property: hasExactSynonym
annotated target: LFT
has synonym type: ABBREVIATION

human growth hormone replacement therapy
type: Class
subclass of: hormone modifying therapy
IAO_0000115: Treatment with growth hormone or analog.
date: 2021-02-09T14:02:34Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: GH replacement therapy
has exact synonym: HGH replacement therapy
has exact synonym: growth hormone therapy
has exact synonym: hGH replacement therapy
has exact synonym: hGH treatment
has exact synonym: human growth hormone therapy
has related synonym: somatotropin replacement therapy

obstetrics and gynecology procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: Any procedure associated with female reproductive organs in their pregnant and non-pregnant states.
date: 2021-02-09T19:21:56Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: OB/GYN procedure

pregnancy test
type: Class
subclass of: obstetrics and gynecology procedure
IAO_0000115: Any examination performed to assess if a female is gravid (pregnant).
date: 2021-02-09T20:02:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92949

HCG measurement
type: Class
subclass of: protein measurement
IAO_0000115: A quantitative measurement of the amount of human chorionic gonadotropin present in urine or serum.
date: 2021-02-09T20:20:44Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: human chorionic gonadotropin measurement

serum HCG measurement
type: Class
subclass of: HCG measurement
subclass of: serum protein measurement
IAO_0000115: A quantitative measurement of the amount of human chorionic gonadotropin present in a sample of serum.
date: 2021-02-09T20:22:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C73495
has exact synonym: blood HCG pregancy test
has exact synonym: serum HCG pregnancy measurement
has exact synonym: serum human chorionic gonadotropin measurement

Axiom
annotated source: serum HCG measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of the amount of human chorionic gonadotropin present in a sample of serum.
has db xref: NCIT:C73495

urine HCG measurement
type: Class
subclass of: HCG measurement
subclass of: urine protein measurement
IAO_0000115: A quantitative measurement of the amount of human chorionic gonadotropin present in a sample of urine.
date: 2021-02-09T20:24:57Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: urine HCG pregancy test
has exact synonym: urine HCG pregnancy measurement
has exact synonym: urine human chorionic gonadotropin measurement

blood chemistry measurement
type: Class
subclass of: hematology testing
subclass of: clinical chemistry assessment
IAO_0000115: The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory.
date: 2021-02-09T20:32:13Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C47868
has exact synonym: blood chemistry test

Axiom
annotated source: blood chemistry measurement
annotated property: IAO_0000115
annotated target: The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory.
has db xref: NCIT:C47868

serum chemistry measurement
type: Class
subclass of: blood chemistry measurement
IAO_0000115: A quantitative measurement of a particular substance present in a sample of serum.
date: 2021-02-09T20:41:32Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C61014

Axiom
annotated source: serum chemistry measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of a particular substance present in a sample of serum.
has db xref: NCIT:C61014

urine chemistry measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001088
subclass of: clinical chemistry assessment
subclass of: MAXO_0001452
IAO_0000115: A quantitative measurement of a particular substance present in a sample of urine.
date: 2021-02-09T21:22:57Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C61044

Axiom
annotated source: urine chemistry measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of a particular substance present in a sample of urine.
has db xref: NCIT:C61044

clinical breast examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000310
subclass of: therapeutic procedure by site
subclass of: obstetrics and gynecology procedure
subclass of: chest examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000310
IAO_0000115: A systemic evaluation of the breast using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has broad synonym: breast examination
has db xref: NCIT:C70552
has exact synonym: breast exam
has exact synonym: clinical breast exam
has exact synonym: examination of breast
has exact synonym: physical examination of breast
comment: An exam of the breast performed by a health care provider to check for lumps or other changes. [ NCI ]

Axiom
annotated source: clinical breast examination
annotated property: comment
annotated target: An exam of the breast performed by a health care provider to check for lumps or other changes. [ NCI ]
has db xref: NCIT:C70552

breast self-examination
type: Class
subclass of: clinical breast examination
IAO_0000115: Procedure where the individual examines their own breasts for lumps and other changes.
date: 2021-02-09T21:37:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C70551
has exact synonym: breast self-exam
has exact synonym: breast self-surveillance

Axiom
annotated source: breast self-examination
annotated property: IAO_0000115
annotated target: Procedure where the individual examines their own breasts for lumps and other changes.
has db xref: NCIT:C70551

abdominal examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000916
subclass of: whole body examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000916
IAO_0000115: A systemic evaluation of the abdomen using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has db xref: NCIT:C167415
has exact synonym: abdomen exam
has exact synonym: examination of abdomen
has exact synonym: examination of the abdomen
has exact synonym: physical examination of abdomen

pelvic examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002355
subclass of: therapeutic procedure by site
subclass of: obstetrics and gynecology procedure
subclass of: whole body examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002355
IAO_0000115: A systemic evaluation of the pelvic region of trunk using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has db xref: NCIT:C38104
has exact synonym: examination of pelvic region of trunk
has exact synonym: examination of pelvis
has exact synonym: pelvic exam
has exact synonym: pelvic region of trunk exam
has exact synonym: pelvis examination
has exact synonym: physical examination of pelvic region of trunk

fundal height measurement
type: Class
subclass of: uterine size measurement
IAO_0000115: A measurement generally defined as the distance in centimeters from the pubic bone to the top of the uterus to determine fetal growth.
date: 2021-02-09T22:00:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C154876

uterine size measurement
type: Class
subclass of: uterus examination
IAO_0000115: Determination of the uterine size by ultrasound or other measurement.
date: 2021-02-09T22:03:45Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: uterine size measurement
annotated property: IAO_0000115
annotated target: Determination of the uterine size by ultrasound or other measurement.
has db xref: PMID:16212222

fetal heart rate monitoring
type: Class
subclass of: heart rate measurement
subclass of: prenatal examination
subclass of: MAXO_0001538
IAO_0000115: The act of observing and recording the fetal heart rate for determining the baseline values or other abnormal findings.
date: 2021-02-10T19:36:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92929
has exact synonym: fetal heart monitoring
has exact synonym: fetal heart rate measurement
has narrow synonym: Fetal Doppler heart rate monitoring
comment: External fetal heart rate monitoring is performed using a hand-held Doppler ultrasound probe to auscultate and count the FHR during a uterine contraction and for 30 seconds thereafter to identify fetal response. It may also be performed using an external transducer, which is placed on the maternal abdomen and held in place by an elastic belt or girdle.

Axiom
annotated source: fetal heart rate monitoring
annotated property: IAO_0000115
annotated target: The act of observing and recording the fetal heart rate for determining the baseline values or other abnormal findings.
has db xref: NCIT:C92929
has db xref: PMID:10323356

obsolete fetal Doppler monitoring
type: Class
deprecated: true

internal fetal heart rate monitoring
type: Class
subclass of: fetal heart rate monitoring
IAO_0000115: A technique that utilizes a wire attached to the fetal scalp to monitor fetal heart rate. The wire detects fetal cardiac electrical activity to determine the baseline fetal heart rate and variability.
date: 2021-02-10T19:51:21Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C114083
has exact synonym: FSE
has exact synonym: fetal scalp electrode monitoring

Axiom
annotated source: internal fetal heart rate monitoring
annotated property: IAO_0000115
annotated target: A technique that utilizes a wire attached to the fetal scalp to monitor fetal heart rate. The wire detects fetal cardiac electrical activity to determine the baseline fetal heart rate and variability.
has db xref: NCIT:C114083

Axiom
annotated source: internal fetal heart rate monitoring
annotated property: hasExactSynonym
annotated target: FSE
has synonym type: OMO_0003000

pregnancy diet intake
type: Class
subclass of: prescriptive dietary intake
IAO_0000115: Recommendation for specific nutrients, vitamin supplementation, and food avoidance while pregnant.
date: 2021-02-10T20:05:20Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: pregnancy diet intake recommendation

avoid excessive heat
type: Class
subclass of: therapeutic avoidance of environmental exposure
IAO_0000115: A clinical recommendation to avoid or refrain from excessively hot environments in order to maintain health or ameliorate symptoms.
date: 2021-02-10T21:19:31Z
creator: http://orcid.org/0000-0001-7941-2961

avoid toxoplasmosis exposure
type: Class
subclass of: communicable disease avoidance
IAO_0000115: A recommendation to avoid infection with toxoplasmosis especially when pregnant due to serious risk of passing the infection on to the baby.
date: 2021-02-10T21:19:55Z
creator: http://orcid.org/0000-0001-7941-2961
comment: Cats play an important role in the spread of toxoplasmosis. They become infected by eating infected rodents, birds, or other small animals. The parasite is then passed in the cat’s feces. Kittens and cats can shed millions of parasites in their feces for as long as 3 weeks after infection. Mature cats are less likely to shed Toxoplasma if they have been previously infected. Cats and kittens prefer litter boxes, garden soils, and sandboxes for elimination, and you may be exposed unintentionally by touching your mouth after changing a litter box, or after gardening without gloves. Fruits and vegetables may have contact with contaminated soil or water also, and you can be infected by eating fruits and vegetables if they are not cooked, washed, or peeled.
comment: Risk is most profound by a pregnant mother passing toxoplasmosis to their infant. Infected infants do not have symptoms at birth but can develop serious symptoms later in life, such as blindness or mental disability.

Axiom
annotated source: avoid toxoplasmosis exposure
annotated property: comment
annotated target: Cats play an important role in the spread of toxoplasmosis. They become infected by eating infected rodents, birds, or other small animals. The parasite is then passed in the cat’s feces. Kittens and cats can shed millions of parasites in their feces for as long as 3 weeks after infection. Mature cats are less likely to shed Toxoplasma if they have been previously infected. Cats and kittens prefer litter boxes, garden soils, and sandboxes for elimination, and you may be exposed unintentionally by touching your mouth after changing a litter box, or after gardening without gloves. Fruits and vegetables may have contact with contaminated soil or water also, and you can be infected by eating fruits and vegetables if they are not cooked, washed, or peeled.
has db xref: pregnant.html

Axiom
annotated source: avoid toxoplasmosis exposure
annotated property: comment
annotated target: Risk is most profound by a pregnant mother passing toxoplasmosis to their infant. Infected infants do not have symptoms at birth but can develop serious symptoms later in life, such as blindness or mental disability.
has db xref: pregnant.html

avoid excessive exercise
type: Class
subclass of: physical activity avoidance recommendation
IAO_0000115: Clinical recommendation to avoid strenuous exercise that may increase heart rate and temperature.
date: 2021-02-10T21:22:05Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: abstain from excessive exercise
has exact synonym: avoid strenuous physical work

avoid heavy lifting activities
type: Class
subclass of: physical activity avoidance recommendation
IAO_0000115: A clinical recommendation to avoid or refrain from lifting heavy items in order to maintain health or ameliorate symptoms.
date: 2021-02-10T21:22:33Z
creator: http://orcid.org/0000-0001-7941-2961

avoid destabilizing activities
type: Class
subclass of: physical activity avoidance recommendation
IAO_0000115: Limit activities where a great deal of balance may be required to prevent issues or help the wellbeing of a patient.
date: 2021-02-10T21:23:13Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: avoid acitivities requiring balance

pregnancy education counseling
type: Class
subclass of: behavioral counseling
IAO_0000115: Education by care providers about nutrition, health issues, and resources for prenatal and postnatal care.
date: 2021-02-12T20:01:45Z
creator: http://orcid.org/0000-0001-7941-2961
has narrow synonym: prenatal education counseling
has related synonym: birth class recommendation

obsolete urine protein assessment
type: Class
IAO_0100001: urine protein measurement
deprecated: true

urine glucose measurement
type: Class
subclass of: urine chemistry measurement
IAO_0000115: A measurement of the amount of sugar (glucose) in a urine sample.
date: 2021-02-12T20:44:57Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: urine glucose assessment
has exact synonym: urine glucose monitoring
has exact synonym: urine glucose testing

syphilis screening
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing for sexually transmitted disease syphilis. Syphilis is a contagious bacterial infection caused by the spirochete Treponema pallidum.
date: 2021-02-12T20:56:40Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: syphylis testing

rubella antibody titer testing
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing to determine whether a patient has sufficient antibodies to be protected from rubella virus or to verify infection.
date: 2021-02-12T21:04:52Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: rubella testing

varicella testing
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing to diagnose primary VZV infection (varicella) as well as reactivation (herpes zoster).
date: 2021-02-12T21:26:02Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: VZV testing
has exact synonym: chickenpox testing
has exact synonym: varicella-zoster virus testing

hepatitis B assessement
type: Class
subclass of: infectious disease screening
IAO_0000115: Screening for hepatitis B antibodies to determine if a patient has immunity to hepatitis B.
date: 2021-02-12T21:29:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hep B antibody titer testing
has exact synonym: hep B testing
has exact synonym: hepatitis B testing

hepatitis B surface antigen testing
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing to detect hepatitis B viral antigens and an active hepatitis B infection.
date: 2021-02-12T21:32:40Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: HBsAg testing

HIV screening
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing a patient for the antibodies to the human immunodeficiency virus (HIV).
date: 2021-02-12T21:40:46Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: HIV testing

chlamydia screening
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing to determine if the patient has a chlamydia bacterial infection.
date: 2021-02-12T21:51:15Z
creator: http://orcid.org/0000-0001-7941-2961

gonorrhea testing
type: Class
subclass of: infectious disease screening
IAO_0000115: Testing for the sexually transmitted disease gonorrhea.
date: 2021-02-12T21:54:20Z
creator: http://orcid.org/0000-0001-7941-2961

hepatitis C screening
type: Class
subclass of: infectious disease screening
IAO_0000115: Screening for hepatitis C antibodies to determine if a patient has immunity to hepatitis C.
date: 2021-02-12T21:55:19Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hep C testing

blood specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000178
subclass of: bodily fluid specimen collection
subclass of: MAXO_0001402
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000178
IAO_0000115: Collecting of blood for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-15T12:00:00Z
has exact synonym: blood collection
has exact synonym: blood sampling procedure
has exact synonym: collection of blood specimen

bile specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001970
subclass of: bodily fluid specimen collection
subclass of: MAXO_0001464
IAO_0000115: Collecting of bile for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-15T12:00:00Z
has exact synonym: bile collection
has exact synonym: collection of bile specimen

blood typing procedure
type: Class
subclass of: blood cell measurement
IAO_0000115: A procedure to tell what a patient's blood type and cell surface markers are.
date: 2021-02-16T15:17:39Z
creator: http://orcid.org/0000-0001-7941-2961

ABO blood typing procedure
type: Class
subclass of: blood typing procedure
IAO_0000115: A procedured performed to determine the antigens patient's red blood cells (RBCs) that correspond to the four main blood groups: A, B, O, and AB.
date: 2021-02-16T15:25:11Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: ABO blood type testing

Rh factor blood typing procedure
type: Class
subclass of: blood typing procedure
IAO_0000115: Testing to determine whether the protien Rhesus (Rh) factor is present on patient's red blood cells. If the protein is present, the patient is said to be Rh positive. If the protein is not present, the patient is Rh negative.
date: 2021-02-16T15:34:20Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Rh factor blood testing
has exact synonym: Rhesus factor blood testing

hemoglobin measurement
type: Class
subclass of: hematology testing
IAO_0000115: A quantitative measurement of the amount of hemoglobin present in a sample.
date: 2021-02-16T20:10:36Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64848
has exact synonym: HGB measurement

Axiom
annotated source: hemoglobin measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of the amount of hemoglobin present in a sample.
has db xref: NCIT:C64848

reticulocyte count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000558
subclass of: clinical cell count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000558
IAO_0000115: A determination of the number of reticulocyte in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C51947
has exact synonym: reticulocyte count test

serum iron measurement
type: Class
subclass of: serum chemistry measurement
IAO_0000115: A quantitative measurement of the amount of iron in serum.
date: 2021-02-16T20:19:31Z
creator: http://orcid.org/0000-0001-7941-2961

serum ferritin measurement
type: Class
subclass of: serum chemistry measurement
IAO_0000115: A quantitative measurement determining the amount of ferritin in serum as an indicator of iron metabolism.
date: 2021-02-16T20:21:40Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: serum ferritin level measurement

total iron binding capacity measurement
type: Class
subclass of: serum chemistry measurement
IAO_0000115: The determination of the saturation of iron binding sites on serum transferrin proteins.
date: 2021-02-16T20:30:55Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: iron-binding capacity assessment
has db xref: NCIT:C74718
has exact synonym: IBCT
has exact synonym: TIBC
has exact synonym: total iron binding content measurement

Axiom
annotated source: total iron binding capacity measurement
annotated property: IAO_0000115
annotated target: The determination of the saturation of iron binding sites on serum transferrin proteins.
has db xref: NCIT:C74718

Axiom
annotated source: total iron binding capacity measurement
annotated property: hasExactSynonym
annotated target: IBCT
has synonym type: OMO_0003000

Axiom
annotated source: total iron binding capacity measurement
annotated property: hasExactSynonym
annotated target: TIBC
has synonym type: OMO_0003000

blood cell measurement
type: Class
subclass of: cell measurement
subclass of: hematology testing
IAO_0000115: A measurement of size, shape, number, or other parameter of blood cells in order to diagnose or treat a patient.
date: 2021-02-16T20:40:24Z
creator: http://orcid.org/0000-0001-7941-2961

erythrocyte morphology measurement
type: Class
equivalent class: Class
  intersection of: cell morphology assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000051
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000232
subclass of: blood cell measurement
subclass of: MAXO_0001381
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000232
IAO_0000115: A determination of the structure of erythrocyte.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-03-03T20:39:14Z
has db xref: NCIT:C92296
has exact synonym: RBC morphology measurement
has exact synonym: erythrocyte morphology assessment
has exact synonym: red blood cell morphology measurement

blood smear test
type: Class
subclass of: blood cell measurement
IAO_0000115: A procedure taking a thin layer of blood smeared on a glass microscope slide and stained to allow blood cells to be examined with a microscope.
date: 2021-02-16T20:44:14Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: blood film test
has exact synonym: peripheral blood film test
has exact synonym: peripheral blood smear

serum creatinine measurement
type: Class
subclass of: serum chemistry measurement
IAO_0000115: A quantitative measurement of the amount of creatinine present in a sample of serum.
date: 2021-02-16T20:56:49Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C61023
comment: Serves to assist in the evaluation of renal function.

Axiom
annotated source: serum creatinine measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of the amount of creatinine present in a sample of serum.
has db xref: NCIT:C61023

Axiom
annotated source: serum creatinine measurement
annotated property: comment
annotated target: Serves to assist in the evaluation of renal function.
has db xref: PMID:29763080

thyroid-stimulating hormone test
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR_000028269
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0000178
subclass of: protein measurement in blood
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR_000028269
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000178
IAO_0000115: The determination of the amount of thyroid stimulating hormone present in blood.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:03:38Z
has exact synonym: TSH level test
has exact synonym: blood thyroid stimulating hormone test
has exact synonym: thyroid stimulating hormone blood assessment

T4 thyroid hormone test
type: Class
subclass of: blood chemistry measurement
IAO_0000115: Determination of thyroxine (T4) levels in the blood as an indicator of thyroid health.
date: 2021-02-16T21:05:40Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: T4 level test
has exact synonym: thyroxine level test

T3 thyroid hormone test
type: Class
subclass of: blood chemistry measurement
IAO_0000115: Determination of triiodothyronine (T3) levels in blood as an indicator of thyroid health.
date: 2021-02-16T21:05:52Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: T3 level test
has exact synonym: triiodothyronine level test

blood coagulation test
type: Class
subclass of: hematology testing
IAO_0000115: A measure of a patient's ability to clot, and how long it takes to clot.
date: 2021-02-16T21:13:53Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C62662
has related synonym: coagulation study

partial thromboplastin time test
type: Class
subclass of: blood coagulation test
IAO_0000115: A measurement of the length of time that it takes for clotting to occur when reagents are added to a plasma specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.
date: 2021-02-16T21:14:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38462
has exact synonym: APTT test
has exact synonym: PTT test
has exact synonym: activated partial thromboplastin time test

prothrombin time/international normalized ratio measurement
type: Class
subclass of: blood coagulation test
IAO_0000115: The determination of the ratio of the prothrombin time in a subject's specimen compared to a control sample. The measurement may be expressed as a ratio or percentage.
date: 2021-02-16T21:19:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C170591
has exact synonym: PT/INR measurement
has exact synonym: PTAC measurement
has exact synonym: prothrombin time actual/control measurement

Axiom
annotated source: prothrombin time/international normalized ratio measurement
annotated property: IAO_0000115
annotated target: The determination of the ratio of the prothrombin time in a subject's specimen compared to a control sample. The measurement may be expressed as a ratio or percentage.
has db xref: NCIT:C170591

thrombin time measurement
type: Class
subclass of: blood coagulation test
IAO_0000115: A measurement of the time it takes a plasma sample to clot after adding the active enzyme thrombin.
date: 2021-02-16T21:23:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C80365
has exact synonym: TCT measurement
has exact synonym: TT measurment
has exact synonym: thrombin clotting time measurement

Axiom
annotated source: thrombin time measurement
annotated property: IAO_0000115
annotated target: A measurement of the time it takes a plasma sample to clot after adding the active enzyme thrombin.
has db xref: NCIT:C80365

alanine transaminase test
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000050341
subclass of: liver function testing
subclass of: MAXO_0020028
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000050341
IAO_0000115: The determination of the amount of alanine aminotransferase (human) present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:34:21Z
has db xref: NCIT:C64433
has exact synonym: ALT test
has exact synonym: GPT test
has exact synonym: SGPT test
has exact synonym: alanine aminotransferase (human) assessment
has exact synonym: alanine aminotransferase (human) test
has exact synonym: alanine transaminase measurement
has exact synonym: serum glutamic-pyruvic transaminase test
comment: Alanine aminotransferase is an enzyme produced mainly in the liver. When serum activity is measured, it provides a marker of hepatic disease.

Axiom
annotated source: alanine transaminase test
annotated property: comment
annotated target: Alanine aminotransferase is an enzyme produced mainly in the liver. When serum activity is measured, it provides a marker of hepatic disease.
has db xref: PMID:1992953

aspartate aminotransferase measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000050353
subclass of: protein measurement
subclass of: liver function testing
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000050353
IAO_0000115: The determination of the amount of aspartate aminotransferase (human) present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:38:44Z
has db xref: NCIT:C64467
has exact synonym: AST blood test
has exact synonym: SGOT test
has exact synonym: aspartate aminotransferase (human) assessment
has exact synonym: aspartate aminotransferase (human) test
has exact synonym: aspartate aminotransferase blood test
has exact synonym: serum glutamic oxaloacetic transaminase test
comment: Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transferase (GGT) are enzymes measured in serum or plasma to investigate liver disease.

Axiom
annotated source: aspartate aminotransferase measurement
annotated property: comment
annotated target: Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transferase (GGT) are enzymes measured in serum or plasma to investigate liver disease.
has db xref: PMID:24072574

gamma glutamyl transpeptidase measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000001351
subclass of: protein measurement
subclass of: liver function testing
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000001351
IAO_0000115: The determination of the amount of gamma-glutamyltranspeptidase present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:42:40Z
has db xref: NCIT:C64847
has exact synonym: GGT test
has exact synonym: GTP test
has exact synonym: gamma-GT test
has exact synonym: gamma-glutamyltranspeptidase assessment
has exact synonym: gamma-glutamyltranspeptidase test
comment: Determination of gamma-glutamyl transferase (GGT) present in the sample as a measurement of liver function.

Axiom
annotated source: gamma glutamyl transpeptidase measurement
annotated property: comment
annotated target: Determination of gamma-glutamyl transferase (GGT) present in the sample as a measurement of liver function.
has db xref: PMID:24072574

albumin measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR P02768
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR P02768
IAO_0000115: The determination of the amount of albumin (human) present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:45:46Z
has db xref: NCIT:C64431
has exact synonym: ALB level test
has exact synonym: albumin (human) assessment
has exact synonym: albumin (human) test
has exact synonym: albumin assessment
has exact synonym: albumin level measurement
has exact synonym: albumin test

alkaline phosphatase measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000023540
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000023540
IAO_0000115: The determination of the amount of alkaline phosphatase present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-16T21:50:44Z
has db xref: NCIT:C64432
has exact synonym: ALP measurement
has exact synonym: alk phos test
has exact synonym: alkaline phosphatase assessment
has exact synonym: alkaline phosphatase test

total bilirubin measurement
type: Class
subclass of: bilirubin measurement
IAO_0000115: The measurement of the total amount of bilirubin present in a particular substrate. The substrate most often tested is blood, but other fluids extracted from the body may be used periodically depending on the purpose of the test.
date: 2021-02-16T21:52:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38037
has exact synonym: BILI measurement
has exact synonym: total bilirubin level measurement

Axiom
annotated source: total bilirubin measurement
annotated property: IAO_0000115
annotated target: The measurement of the total amount of bilirubin present in a particular substrate. The substrate most often tested is blood, but other fluids extracted from the body may be used periodically depending on the purpose of the test.
has db xref: NCIT:C38037

lactate dehydrogenase measurement
type: Class
subclass of: protein measurement
IAO_0000115: The determination of the amount of lactate dehydrogenase present in the sample.
date: 2021-02-17T14:57:21Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64855
has exact synonym: LDH measurement

5'-nucleotidase measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000001800
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000001800
IAO_0000115: The determination of the amount of 5'-nucleotidase present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-17T15:01:15Z
has db xref: NCIT:C79437
has exact synonym: 5 prime nucleotidase measurement
has exact synonym: 5'- nucleotidase measurement
has exact synonym: 5'-nucleotidase assessment
has exact synonym: 5'-nucleotidase test

bilirubin measurement
type: Class
subclass of: clinical chemistry assessment
IAO_0000115: The measurement of bilirubin present in a particular sample.
date: 2021-02-17T15:06:51Z
creator: http://orcid.org/0000-0001-7941-2961

indirect bilirubin measurement
type: Class
subclass of: bilirubin measurement
IAO_0000115: A measurement of the unconjugated or non-water-soluble bilirubin in a biological specimen.
date: 2021-02-17T15:07:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64483

total protein measurement
type: Class
subclass of: protein measurement
IAO_0000115: A quantitative measurement of total protein present in the sample, usually serum or urine.
date: 2021-02-17T15:16:41Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64858

urine protein measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR_000000001
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0001088
subclass of: protein measurement
subclass of: urine chemistry measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR_000000001
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001088
IAO_0000115: The determination of the amount of protein present in urine.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-17T15:25:01Z
has db xref: NCIT:C74760
has exact synonym: protein urine assessment
has exact synonym: urine protein assessment
has exact synonym: urine protein test
has exact synonym: urine protein testing

24-hour urine collection
type: Class
subclass of: total protein measurement
subclass of: urine protein measurement
IAO_0000115: The measurement of the total protein present in a urine sample that was collected over a period of 24 hours.
date: 2021-02-17T16:13:50Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C135567
has exact synonym: 24 hour urine for total protein
has exact synonym: 24-hour urine protein test

Axiom
annotated source: 24-hour urine collection
annotated property: IAO_0000115
annotated target: The measurement of the total protein present in a urine sample that was collected over a period of 24 hours.
has db xref: NCIT:C135567

serum total protein measurement
type: Class
subclass of: serum chemistry measurement
subclass of: total protein measurement
subclass of: serum protein measurement
IAO_0000115: A quantitative measurement of the total amount of protein present in a sample of serum.
date: 2021-02-17T16:23:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C61033

Axiom
annotated source: serum total protein measurement
annotated property: IAO_0000115
annotated target: A quantitative measurement of the total amount of protein present in a sample of serum.
has db xref: NCIT:C61033

haptoglobin measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000008725
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000008725
IAO_0000115: The determination of the amount of haptoglobin present in the sample.
date: 2021-02-17T17:02:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74740
has exact synonym: haptog measurement
has exact synonym: haptoglobin assessment
has exact synonym: haptoglobin protein measurement
has exact synonym: haptoglobin test

hemoglobin electrophoresis test
type: Class
subclass of: protein measurement
IAO_0000115: Determination of the types of normal or abnormal types of hemoglobin in the blood. Some types of hemoglobin are associated with sickle cell disease or anemia.
date: 2021-02-17T19:58:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: Hb ELP
has exact synonym: Hb electrophoresis measurement
has exact synonym: hemoglobin evaluation
has exact synonym: hemoglobin fractionation
has narrow synonym: hemoglobinopathy evaluation
has narrow synonym: sickle cell screen

serum PAPP-A measurement
type: Class
subclass of: serum protein measurement
IAO_0000115: Determination of serum levels of pregnancy-associated plasma protein A (PAPP-A). Maternal levels of PAPP-A increase throughout the pregnancy. Low levels during pregnancy are associated with Down syndrome and trisomy 18.
date: 2021-02-17T20:59:28Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: pregnancy-associated plasma protein A test

glucose tolerance test
type: Class
subclass of: disease screening
IAO_0000115: A test that involves administration of a know quantity of glucose as a means of screening for glucose intolerance or diabetes mellitus. Typically a baseline (fasting plasma or serum glucose) is drawn prior to the administration of the glucose bolus. Serial plasma glucose levels are obtained (e.g. 30min, 1hr, 2hr, 3hr) and a plot of plasma glucose versus time is created. Comparison of these values against standardized results can be used in establishing the diagnosis of glucose intolerance or diabetes mellitus.
date: 2021-02-17T21:38:54Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C45946

Axiom
annotated source: glucose tolerance test
annotated property: IAO_0000115
annotated target: A test that involves administration of a know quantity of glucose as a means of screening for glucose intolerance or diabetes mellitus. Typically a baseline (fasting plasma or serum glucose) is drawn prior to the administration of the glucose bolus. Serial plasma glucose levels are obtained (e.g. 30min, 1hr, 2hr, 3hr) and a plot of plasma glucose versus time is created. Comparison of these values against standardized results can be used in establishing the diagnosis of glucose intolerance or diabetes mellitus.
has db xref: NCIT:C45946

fetal examination
type: Class
subclass of: prenatal examination
subclass of: MAXO_0001538
IAO_0000115: A test or diagnostic examination to assess the health status and well being of the fetus.
date: 2021-02-18T14:38:59Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: fetal assessment
has exact synonym: fetal exam
has exact synonym: foetal examination

Axiom
annotated source: fetal examination
annotated property: IAO_0000115
annotated target: A test or diagnostic examination to assess the health status and well being of the fetus.
has db xref: NCIT:C92714

assessment of fetal presentation
type: Class
subclass of: fetal examination
IAO_0000115: A series of maneuvers to determine the position and presenting part of the fetus with respect to the maternal pelvic canal in preparation for labor and the birth process.
date: 2021-02-18T14:53:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92737
has exact synonym: fetal presentation assessment
has narrow synonym: fetal position assessment

Axiom
annotated source: assessment of fetal presentation
annotated property: IAO_0000115
annotated target: A series of maneuvers to determine the position and presenting part of the fetus with respect to the maternal pelvic canal in preparation for labor and the birth process.
has db xref: NCIT:C92737

labor induction
type: Class
subclass of: obstetrics and gynecology procedure
IAO_0000115: The use of pharmacological and/or mechanical methods to initiate labor, including spontaneous rupture of membranes without contractions. Examples of methods include: artificial rupture of membranes, balloons, oxytocin, prostaglandin, laminaria, or other cervical ripening agents. (adapted from reVITALize)
date: 2021-02-18T15:06:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92814
has exact synonym: induction of labor

Axiom
annotated source: labor induction
annotated property: IAO_0000115
annotated target: The use of pharmacological and/or mechanical methods to initiate labor, including spontaneous rupture of membranes without contractions. Examples of methods include: artificial rupture of membranes, balloons, oxytocin, prostaglandin, laminaria, or other cervical ripening agents. (adapted from reVITALize)
has db xref: NCIT:C92814

obsolete fetal Doppler velocimetry
type: Class
deprecated: true

fetal pulse oximetry
type: Class
subclass of: pulse oximetry
subclass of: fetal examination
IAO_0000115: A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter.
date: 2021-02-18T15:16:22Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: fetal pulse oximetry
annotated property: IAO_0000115
annotated target: A method to assess fetal oxygenation status during labor and delivery using a noninvasive reflectance pulse oximeter.
has db xref: NCIT:C92794

protein measurement in blood
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR_000000001
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0000178
subclass of: protein measurement
subclass of: blood chemistry measurement
subclass of: MAXO_0001402
subclass of: MAXO_0001447
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR_000000001
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000178
IAO_0000115: The determination of the amount of protein present in blood.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-17T15:25:01Z
has exact synonym: blood protein test
has exact synonym: protein blood assessment

obstetric abdominal examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: UBERON_0009097
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0000916
subclass of: therapeutic procedure by site
subclass of: obstetrics and gynecology procedure
subclass of: abdominal examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: UBERON_0009097
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000916
IAO_0000115: A systemic evaluation of the abdomen using visual inspection, palpation, and percussion during pregnancy to determine the health of the mother and fetus.
date: 2021-05-27T15:12:17Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: abdominal examination during pregnancy
has exact synonym: pregnant abdomen examination

pregnancy HCG test
type: Class
subclass of: pregnancy test
subclass of: HCG measurement
IAO_0000115: A quantitative measurement of the amount of human chorionic gonadotropin present in urine or serum for the purpose of determining whether the patient is pregnant.
date: 2021-05-27T19:38:10Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: HCG pregnancy test

obstetric cervical examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: UBERON_0009097
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0004801
subclass of: cervical examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: UBERON_0009097
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004801
IAO_0000115: A systemic evaluation of the cervix during pregnancy to determine dilation and effacement of the cervix, cervical position and consistancy, and fetal position.
date: 2021-06-07T18:34:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: cervical exam while pregnant
has exact synonym: obstetric examination of the cervix.
has exact synonym: pregnant cervical exam

cancer screening breast examination
type: Class
subclass of: cancer screening
subclass of: clinical breast examination
IAO_0000115: An evaluation of the breast using visual inspection, palpation, and percussion for the specific purpose of identifying breast changes which may be cancer.
date: 2021-06-07T18:51:49Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: cancer breast exam

hearing examination
type: Class
subclass of: MAXO_0001445
IAO_0000115: A test that evaluates of the sensitivity of a person's sense of hearing and is used to determine a person's hearing sensitivity at different frequencies.
date: 2021-06-07T21:03:43Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: hearing assessment
has exact synonym: hearing exam
has exact synonym: hearing test

albumin test for liver function
type: Class
subclass of: liver function testing
subclass of: albumin measurement
IAO_0000115: The determination of the amount of albumin (human) present in the sample in order to assess the liver's function.
date: 2021-06-08T14:05:06Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: albumin test for liver function assessment
has exact synonym: liver function albumin test

5'-nucleotidase measurement for liver function
type: Class
subclass of: liver function testing
subclass of: 5'-nucleotidase measurement
IAO_0000115: The determination of the amount of 5'-nucleotidase present in the sample to assess liver function.
date: 2021-06-08T14:17:21Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: 5'-nucleotidase test for liver function assessment
has exact synonym: liver function 5'-nucleotidase measurement
has exact synonym: liver function 5'-nucleotidase test

alkaline phosphatase measurement for liver function
type: Class
subclass of: liver function testing
subclass of: alkaline phosphatase measurement
IAO_0000115: The determination of the amount of alkaline phosphatase present in the sample for assessment of liver function.
date: 2021-06-08T14:20:25Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: alkaline phosphatase measurement for liver function assessment
has exact synonym: liver function alk phos test
has exact synonym: liver function alkaline phosphatase measurement

calcium assessment for liver function
type: Class
subclass of: calcium assessment
subclass of: liver function testing
IAO_0000115: A quantitative measurement of the amount of calcium present in a sample, usually serum or urine for the assessment of liver function.
date: 2021-06-08T14:23:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: calcium test for liver function assessement
has exact synonym: liver function calcium test

lactate dehydrogenase measurement for liver assessment
type: Class
subclass of: liver function testing
subclass of: lactate dehydrogenase measurement
IAO_0000115: The determination of the amount of lactate dehydrogenase present in the sample to assess liver function.
date: 2021-06-08T14:34:11Z
creator: http://orcid.org/0000-0001-7941-2961

total bilirubin measurement for assessment of liver function
type: Class
subclass of: liver function testing
subclass of: total bilirubin measurement
IAO_0000115: The measurement of the total amount of bilirubin present in a particular substrate in order to assess liver function. The substrate most often tested is blood, but other fluids extracted from the body may be used periodically depending on the purpose of the test.
date: 2021-06-08T14:47:38Z
creator: http://orcid.org/0000-0001-7941-2961

indirect bilirubin measurement for assessment of liver function
type: Class
subclass of: liver function testing
subclass of: indirect bilirubin measurement
IAO_0000115: A measurement of the unconjugated or non-water-soluble bilirubin in a biological specimen to assess liver function.
date: 2021-06-08T15:31:21Z
creator: http://orcid.org/0000-0001-7941-2961

behavioral intervention
type: Class
subclass of: cognitive and behavioral intervention
IAO_0000115: The use of operant conditioning, including rewards and punishments, in helping a person create an atmosphere where he or she does not contribute to painful stimuli.
date: 2021-08-05T17:18:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15184
has exact synonym: behavior conditioning therapy
has exact synonym: behavioral modification
has exact synonym: behavioral treatment
has exact synonym: behavioural intervention
has exact synonym: behavioural modification

Axiom
annotated source: behavioral intervention
annotated property: IAO_0000115
annotated target: The use of operant conditioning, including rewards and punishments, in helping a person create an atmosphere where he or she does not contribute to painful stimuli.
has db xref: NCIT:C15184

cognitive behavior therapy
type: Class
subclass of: behavioral counseling
subclass of: behavioral intervention
IAO_0000115: A type of psychotherapy utilized to treat different forms of mental disorders.The treatment involves the identification of unhelpful or destructive patterns of thinking and behaviors and the subsequent replacement with behaviors that are beneficial and constructive.
date: 2021-08-05T17:53:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C64345
has exact synonym: cognitive therapy

Axiom
annotated source: cognitive behavior therapy
annotated property: IAO_0000115
annotated target: A type of psychotherapy utilized to treat different forms of mental disorders.The treatment involves the identification of unhelpful or destructive patterns of thinking and behaviors and the subsequent replacement with behaviors that are beneficial and constructive.
has db xref: NCIT:C64345

behavioral dietary intervention
type: Class
subclass of: dietary intervention
subclass of: behavioral intervention
IAO_0000115: The use of operant conditioning to alter a person's dietary choices and behaviors.
date: 2021-08-05T17:56:02Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C67021

Axiom
annotated source: behavioral dietary intervention
annotated property: IAO_0000115
annotated target: The use of operant conditioning to alter a person's dietary choices and behaviors.
has db xref: NCIT:C67021

surgical removal procedure
type: Class
subclass of: surgical procedure
IAO_0000115: A surgical procedure that leads to the removal of body part or body fluid.
date: 2021-08-05T19:16:15Z
creator: http://orcid.org/0000-0001-7941-2961

kidney function testing
type: Class
subclass of: MAXO_0001399
IAO_0000115: A laboratory procedure that evaluates the kidney function.
date: 2021-08-06T18:59:22Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C74972
has exact synonym: renal function test

Axiom
annotated source: kidney function testing
annotated property: IAO_0000115
annotated target: A laboratory procedure that evaluates the kidney function.
has db xref: NCIT:C74972

glomerular filtration rate test
type: Class
subclass of: kidney function testing
IAO_0000115: A measurement of the volume of fluid filtered from the renal glomerular capillaries into the Bowman's capsule per unit time.
date: 2021-08-09T13:28:29Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: GFR test

Axiom
annotated source: glomerular filtration rate test
annotated property: hasExactSynonym
annotated target: GFR test
has synonym type: OMO_0003000

estimated glomerular filtration rate calculation
type: Class
subclass of: glomerular filtration rate test
IAO_0000115: An estimated rate of glomerular filtration is calculated from blood creatinine test, age, body size and gender.
date: 2021-08-09T15:51:41Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: eGFR test

renal calculi removal
type: Class
subclass of: calculi removal
IAO_0000115: Removal of hard deposits made of minerals and salts also called 'kidney stones' or 'renal calculi' by any of a number of methods.
date: 2021-08-09T16:22:26Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: kidney stone removal

calculi removal
type: Class
subclass of: surgical removal procedure
IAO_0000115: Removal of hard deposits made of minerals and salts also called 'stones' or 'calculi' by any of a number of methods. Stones can be found in the kidney, gallbladder, urethra, salivary gland or other ducts.
date: 2021-08-09T16:46:18Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: stone removal

lithotripsy
type: Class
subclass of: calculi removal
IAO_0000115: A procedure to break a stone into small particles that can be more easily cleared from the body.
date: 2021-08-09T17:17:19Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C51994

Axiom
annotated source: lithotripsy
annotated property: IAO_0000115
annotated target: A procedure to break a stone into small particles that can be more easily cleared from the body.
has db xref: NCIT:C51994

renal lithotripsy
type: Class
subclass of: renal calculi removal
subclass of: lithotripsy
IAO_0000115: A treatment to remove kidney snotes by sending ultrasonic energy/shock waves directly to the stone.
date: 2021-08-09T17:20:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: kidney lithotripsy

laser lithotripsy
type: Class
subclass of: lithotripsy
IAO_0000115: A scope is inserted in the urinary tract to locate the stone. Using an optical fiber, laser light is directly emitted to the stone causing stone fragmentation.
date: 2021-08-09T17:21:56Z
creator: http://orcid.org/0000-0001-7941-2961

extracorporeal shock wave lithotripsy
type: Class
subclass of: lithotripsy
IAO_0000115: Using a lithotripter to aim sound waves directly at stones through the body, the shock waves break down stones or calculi which are then able to pass.
date: 2021-08-09T17:22:14Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: ESWL
has exact synonym: extracorporeal shock-wave lithotripsy
has exact synonym: shock wave lithotripsy
has exact synonym: shock-wave lithotripsy

Axiom
annotated source: extracorporeal shock wave lithotripsy
annotated property: hasExactSynonym
annotated target: ESWL
has synonym type: OMO_0003000

percutaneous nephrolithotomy
type: Class
subclass of: renal calculi removal
IAO_0000115: A small cut is made through the patient's back and a nephroscope is inserted to locate and remove the kidney stone.
date: 2021-08-09T18:17:54Z
creator: http://orcid.org/0000-0001-7941-2961

obsolete ureteroscopy
type: Class
IAO_0100001: ureteroscopy
deprecated: true

ureteroscopic stone removal
type: Class
subclass of: surgery by body site
subclass of: calculi removal
subclass of: ureteroscopy
subclass of: MAXO_0001412
subclass of: MAXO_0001443
IAO_0000115: A ureteroscope is inserted into the ureter and a wire basket inserted through the tube to remove the stone(s). In addition, a laser or other mechanical device can be used to break up the stone(s).
date: 2021-08-09T18:26:36Z
creator: http://orcid.org/0000-0001-7941-2961

purine antagonist agent therapy
type: Class
subclass of: antimetabolite agent therapy
IAO_0000115: Treatment with an antimetabolite that affects the metabolism and utilization of purines.
date: 2021-08-09T19:15:23Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C1556
has exact synonym: purine inhibitor agent therapy

electrocardiography
type: Class
subclass of: diagnostic procedure of cardiovascular system
IAO_0000115: A procedure that displays the electrical activity of the heart.
date: 2021-08-09T19:19:35Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38053
has exact synonym: ECG
has exact synonym: EKG
has exact synonym: electrocardiogram procedure

Axiom
annotated source: electrocardiography
annotated property: IAO_0000115
annotated target: A procedure that displays the electrical activity of the heart.
has db xref: NCIT:C38053

Axiom
annotated source: electrocardiography
annotated property: hasExactSynonym
annotated target: ECG
has synonym type: OMO_0003000

Axiom
annotated source: electrocardiography
annotated property: hasExactSynonym
annotated target: EKG
has synonym type: OMO_0003000

aspirin therapy
type: Class
subclass of: NSAID therapy
IAO_0000115: Treatment with acetylsalicylic acid. It is often a treatment for pain, fever, inflammation or to reduce risk of heart attack.
date: 2021-08-10T14:35:53Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: acetylsalicylic acid therapy
has exact synonym: treatment with aspirin

alpha-glucosidase inhibitor therapy
type: Class
subclass of: antidiabetic agent therapy
IAO_0000115: Treatment with an inhibitor that inteferes with the action of alpha-glucosidase.
date: 2021-08-10T14:39:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:67239

benzodiazepine agent therapy
type: Class
subclass of: anxiolytic agent therapy
IAO_0000115: Treatment with one of a group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring. It is often used to treat anxiety.
date: 2021-08-10T14:58:25Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:22720

T-type calcium channel blocking agent therapy
type: Class
subclass of: calcium channel blocking agent therapy
IAO_0000115: Treatment with a pharmaceutical agent that inhibits T-type calcium channels.
date: 2021-08-10T15:05:39Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: T-type calcium channel antagonist therapy

L-type calcium channel blocking agent therapy
type: Class
subclass of: calcium channel blocking agent therapy
IAO_0000115: Treatment with a pharmaceutical agent that inhibits L-type calcium channels.
date: 2021-08-10T15:10:56Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: L-type calcium channel antagonist therapy

phosphodiesterase inhibitor therapy
type: Class
subclass of: enzyme inhibitor agent therapy
IAO_0000115: Treatment with a phosphodiesterase (PDE) inhibitor.
date: 2021-08-10T15:15:41Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: PDE inhibitor therapy

weight loss pharmacotherapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: An agent or drug used to reduce or control weight.
date: 2021-08-10T18:20:00Z
creator: http://orcid.org/0000-0001-7941-2961

anti-obesity agent therapy
type: Class
subclass of: weight loss pharmacotherapy
IAO_0000115: Treatment with an agent or drug to reduce or control weight in obese patients.
date: 2021-08-10T18:21:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:74518

pain management for palliative care
type: Class
subclass of: palliative care
subclass of: pain management
IAO_0000115: The management of pain by interventional procedures, pharmacotherapy, physical therapy, psychological counseling, or complementary and alternative medical therapies designed to treat or alleviate pain specifically for patients receiving palliative care treatment.
date: 2021-08-11T14:13:00Z
creator: http://orcid.org/0000-0001-7941-2961

assessment for sleep disturbance
type: Class
subclass of: diagnostic procedure
IAO_0000115: A measurement or assessment to determine if a patient's sleep is disrupted.
date: 2021-08-11T14:52:56Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: assessement for sleep disorders
has exact synonym: sleep assessment
has exact synonym: sleep disturbance screening

sleep assessment questionnaire
type: Class
subclass of: assessment for sleep disturbance
IAO_0000115: A questionnaire designed to determine sleep quality, daytime sleepiness, or other issues related to having restful sleep.
date: 2021-08-11T14:56:38Z
creator: http://orcid.org/0000-0001-7941-2961

actigraphy
type: Class
subclass of: assessment for sleep disturbance
IAO_0000115: Use of a portable device (actigraph) to study sleep-wake patterns and circadian rhythms by assessing movement.
date: 2021-08-11T14:59:42Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: actigraphy
annotated property: IAO_0000115
annotated target: Use of a portable device (actigraph) to study sleep-wake patterns and circadian rhythms by assessing movement.
has db xref: PMID:26608435

polysomnography
type: Class
subclass of: assessment for sleep disturbance
IAO_0000115: A group of tests (usually central electroencephalogram (EEG) (C3 or C4), reference occipital EEG (O1 or O2), right and left electro-oculogram (EOG), mental or submental electromylogram (EMG), thoracic effort, abdominal effort, nasal and oral airflow, a microphone to record snoring, pulse oxygen saturation, EKG, and video recording to document body positions during sleep) taken during sleep.
date: 2021-08-11T15:00:34Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C114185
has exact synonym: PSG

Axiom
annotated source: polysomnography
annotated property: IAO_0000115
annotated target: A group of tests (usually central electroencephalogram (EEG) (C3 or C4), reference occipital EEG (O1 or O2), right and left electro-oculogram (EOG), mental or submental electromylogram (EMG), thoracic effort, abdominal effort, nasal and oral airflow, a microphone to record snoring, pulse oxygen saturation, EKG, and video recording to document body positions during sleep) taken during sleep.
has db xref: PMID:26608435

Axiom
annotated source: polysomnography
annotated property: hasExactSynonym
annotated target: PSG
has synonym type: OMO_0003000

obsolete airway endoscopy
type: Class
IAO_0100001: bronchoscopy
deprecated: true

placement of a stent
type: Class
subclass of: medical device implantation
IAO_0000115: Insertion of a tube into a blocked passageway, such as a blood vessel, to keep it open.
date: 2021-08-11T16:01:02Z
creator: http://orcid.org/0000-0001-7941-2961
has related synonym: stenting

insertion of a nasopharyngeal stent
type: Class
subclass of: placement of a stent
IAO_0000115: A tube-shaped medical device is inserted into the nasal passage to prevent obstruction of the airway.
date: 2021-08-11T16:26:00Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: placement of nasal stent
has exact synonym: placement of nasopharyngeal stent

dietician evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial evaluation by a professional trained and qualified to provide nutritional services at individual, institutional and community levels in term of assessing nutritional needs.
date: 2021-08-11T17:06:20Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C28248
has narrow synonym: nutritionist evaluation

physical therapist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial evaluation by a trained and certified individual who applies knowledge of the concepts, principles, and practices of physical therapy for the treatment or prevention of physical disability or disease.
date: 2021-08-11T17:11:32Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C53422
has exact synonym: physiotherapist evaluation

respiratory therapist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial assessment by a professional trained and qualified to perform technical work concerned with administering therapeutic and diagnostic respiratory care and life support to patients with cardiopulmonary deficiencies and abnormalities.
date: 2021-08-11T17:34:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C53425

social worker evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial assessment by a professionally trained person who is employed in the administration of charity, social service, and welfare. The assistance this professional provides helps disadvantaged individuals and families adjust themselves to the community.
date: 2021-08-11T17:59:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C28190

newborn examination
type: Class
subclass of: physical examination
IAO_0000115: A general assessment of the overall health of a newborn.
date: 2021-08-11T19:22:27Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C84749

Axiom
annotated source: newborn examination
annotated property: IAO_0000115
annotated target: A general assessment of the overall health of a newborn.
has db xref: NCIT:C84749

newborn behavior examination
type: Class
subclass of: newborn examination
IAO_0000115: The assessment of behavior in neonates.
date: 2021-08-11T19:25:11Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C81314

Axiom
annotated source: newborn behavior examination
annotated property: IAO_0000115
annotated target: The assessment of behavior in neonates.
has db xref: NCIT:C81314

Apgar testing
type: Class
subclass of: newborn examination
IAO_0000115: A test conducted at 1 minute and 5 minutes after birth to determine the overall health of the newborn.
date: 2021-08-11T19:31:30Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C81230

intrapartum fetal stimulation
type: Class
subclass of: obstetrics and gynecology procedure
IAO_0000115: Any method used to elicit a fetal heart rate acceleration response during labor.
date: 2021-08-11T19:47:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C114084

Axiom
annotated source: intrapartum fetal stimulation
annotated property: IAO_0000115
annotated target: Any method used to elicit a fetal heart rate acceleration response during labor.
has db xref: NCIT:C114084

newborn heart rate measurement
type: Class
subclass of: heart rate measurement
subclass of: newborn examination
IAO_0000115: Determination of the newborn's heart rate.
date: 2021-08-11T20:53:10Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C87103

manual fetal rotation
type: Class
subclass of: obstetrics and gynecology procedure
IAO_0000115: A procedure during labor in which the occiput is manually rotated from posterior to anterior.
date: 2021-08-11T20:56:18Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C114133

Axiom
annotated source: manual fetal rotation
annotated property: IAO_0000115
annotated target: A procedure during labor in which the occiput is manually rotated from posterior to anterior.
has db xref: NCIT:C114133

external fetal rotation
type: Class
subclass of: obstetrics and gynecology procedure
IAO_0000115: A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation.
date: 2021-08-11T20:58:11Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92776

Axiom
annotated source: external fetal rotation
annotated property: IAO_0000115
annotated target: A manual method of maneuvering the fetus from outside the mother's abdomen to convert a breech into a cephalic presentation.
has db xref: NCIT:C92776

speech therapy
type: Class
subclass of: therapy
IAO_0000115: The treatment of communication disorders (speech disorders and language disorders), cognitive-communication disorders, voice disorders, and swallowing disorders.
date: 2021-08-12T13:17:16Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C159273
has exact synonym: speech language therapy

Axiom
annotated source: speech therapy
annotated property: IAO_0000115
annotated target: The treatment of communication disorders (speech disorders and language disorders), cognitive-communication disorders, voice disorders, and swallowing disorders.
has db xref: NCIT:C159273

psychologist evaluation
type: Class
subclass of: allied health professional evaluation
IAO_0000115: An initial assessment by a person who specializes in the study of mind and behavior or in the treatment of mental, emotional, and behavioral disorders.
date: 2021-08-12T13:32:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C28181

electroencephalography
type: Class
subclass of: MAXO_0020031
IAO_0000115: The neurophysiologic exploration of the electrical activity of the brain by the application of electrodes to the scalp. The resulting traces are known as an electroencephalogram (EEG). This test is used to assess brain damage, epilepsy and other problems.
date: 2021-08-12T13:47:43Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38054
has exact synonym: EEG

Axiom
annotated source: electroencephalography
annotated property: IAO_0000115
annotated target: The neurophysiologic exploration of the electrical activity of the brain by the application of electrodes to the scalp. The resulting traces are known as an electroencephalogram (EEG). This test is used to assess brain damage, epilepsy and other problems.
has db xref: NCIT:C38054

Axiom
annotated source: electroencephalography
annotated property: hasExactSynonym
annotated target: EEG
has synonym type: OMO_0003000

enzyme replacement or supplementation therapy
type: Class
subclass of: biologic therapy
IAO_0000115: Treatment with a synthetic enzyme or mixture of enzymes used to replace or supplement enzymes to treat enzyme deficiency.
date: 2021-08-12T13:51:53Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C29726

urine phosphoethanolamine measurement
type: Class
subclass of: urine chemistry measurement
IAO_0000115: Detection of phosphoethanolamine in urine.
date: 2021-08-12T13:57:56Z
creator: http://orcid.org/0000-0001-7941-2961

bone specific alkaline phosphatase measurement
type: Class
subclass of: alkaline phosphatase measurement
IAO_0000115: The determination of the amount of bone specific alkaline phosphatase present in a sample.
date: 2021-08-12T14:00:14Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C92287
has exact synonym: ALPBS test
has exact synonym: bone ALP measurement

Axiom
annotated source: bone specific alkaline phosphatase measurement
annotated property: IAO_0000115
annotated target: The determination of the amount of bone specific alkaline phosphatase present in a sample.
has db xref: NCIT:C92287

Axiom
annotated source: bone specific alkaline phosphatase measurement
annotated property: hasExactSynonym
annotated target: ALPBS test
has synonym type: OMO_0003000

Axiom
annotated source: bone specific alkaline phosphatase measurement
annotated property: hasExactSynonym
annotated target: bone ALP measurement
has synonym type: OMO_0003000

alkaline phosphatase enzyme activity test
type: Class
subclass of: alkaline phosphatase measurement
IAO_0000115: Measurement of alkaline phosphatase enzamatic activity in a biological sample.
date: 2021-08-12T14:13:09Z
creator: http://orcid.org/0000-0001-7941-2961

inorganic pyrophosphate measurement
type: Class
subclass of: clinical chemistry assessment
IAO_0000115: The determination of the amount of inorganic pyrophosphate present in a sample.
date: 2021-08-12T15:24:26Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C161358
has exact synonym: PPI measurement
has exact synonym: PPi measurement

Axiom
annotated source: inorganic pyrophosphate measurement
annotated property: hasExactSynonym
annotated target: PPI measurement
has synonym type: OMO_0003000

Axiom
annotated source: inorganic pyrophosphate measurement
annotated property: hasExactSynonym
annotated target: PPi measurement
has synonym type: OMO_0003000

resective brain surgery
type: Class
subclass of: surgical resection
IAO_0000115: Open brain surgery to remove part of the brain causing seizures.
date: 2021-08-12T15:36:25Z
creator: http://orcid.org/0000-0001-7941-2961

stimulation procedure
type: Class
subclass of: therapeutic procedure
IAO_0000115: Procedure to arouse the body or parts to increase functional activity.
date: 2021-08-12T15:41:57Z
creator: http://orcid.org/0000-0001-7941-2961

responsive neurostimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: Placement of a stimulator electrode in the part of the brain causing seizures.
date: 2021-08-12T15:44:05Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: RNS

extracardiac nerve stimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: Stimulation of the nerves that are outside of the heart.
date: 2021-08-12T15:47:24Z
creator: http://orcid.org/0000-0001-7941-2961

vagus nerve stimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: A procedure that uses a device to stimulate the vagus nerve with electrical impulses.
date: 2021-08-12T19:05:29Z
creator: http://orcid.org/0000-0001-7941-2961

deep brain stimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: A neurosurgical procedure involving the placement of a medical device called a neurostimulator (sometimes referred to as a "brain pacemaker"), which sends electrical impulses, through implanted electrodes, to specific targets in the brain (brain nuclei) for the treatment of movement disorders, including Parkinson's disease, essential tremor, and dystonia.[1] and other conditions such as obsessive-compulsive disorder and epilepsy.
date: 2021-08-12T19:24:31Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: DBS

Axiom
annotated source: deep brain stimulation
annotated property: IAO_0000115
annotated target: A neurosurgical procedure involving the placement of a medical device called a neurostimulator (sometimes referred to as a "brain pacemaker"), which sends electrical impulses, through implanted electrodes, to specific targets in the brain (brain nuclei) for the treatment of movement disorders, including Parkinson's disease, essential tremor, and dystonia.[1] and other conditions such as obsessive-compulsive disorder and epilepsy.
has db xref: Deep brain stimulation

Axiom
annotated source: deep brain stimulation
annotated property: hasExactSynonym
annotated target: DBS
has synonym type: OMO_0003000

cranial electrical stimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: The use of skin electrodes to pass a low intensity, pulsed electrical current through the scalp and into the brain. This procedure is used to treat a variety of illnesses including anxiety, depression, and chronic pain.
date: 2021-08-12T19:29:07Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C116561

spinal cord stimulation
type: Class
subclass of: stimulation procedure
IAO_0000115: An invasive procedure to stimulate the spinal cord to aid in the management of chronic, intractable pain of the trunk and/or limbs, including unilateral or bilateral pain.
date: 2021-08-12T19:30:24Z
creator: http://orcid.org/0000-0001-7941-2961

surgical procedure on nervous system
type: Class
equivalent class: Class
  intersection of: surgery by body site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001016
subclass of: surgery by body site
subclass of: MAXO_0001419
IAO_0000115: Any surgical procedure conducted on the nervous system.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-12T19:44:10Z
has exact synonym: nervous system surgical procedure
has exact synonym: neurosurgery
has exact synonym: neurosurgical procedure

brain surgery
type: Class
subclass of: surgical procedure on nervous system
IAO_0000115: Surgery performed on any part of the brain.
date: 2021-08-12T19:45:31Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C154268

Axiom
annotated source: brain surgery
annotated property: IAO_0000115
annotated target: Surgery performed on any part of the brain.
has db xref: NCIT:C154268

craniotomy
type: Class
subclass of: surgical procedure on nervous system
IAO_0000115: Surgical creation of an opening of the skull.
date: 2021-08-12T19:47:17Z
creator: http://orcid.org/0000-0001-7941-2961
has broad synonym: cranial surgery
has db xref: NCIT:C15214

Axiom
annotated source: craniotomy
annotated property: IAO_0000115
annotated target: Surgical creation of an opening of the skull.
has db xref: NCIT:C15214

calcitonin treatment
type: Class
subclass of: biologic therapy
IAO_0000115: Treatment with a hormone that is naturally produced in the thyroid. When calcitonin given to patients with osteoporosis, calcitonin produces modest increases in bone mass because it slows the rate at which osteoclasts absorb bone.
date: 2021-08-12T19:57:09Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: calcitonin therapy

supportive care
type: Class
subclass of: cognitive and behavioral intervention
IAO_0000115: Supportive therapy involves the teaching of such life skills as managing medication, learning to socialize, handling finances, and getting a job.
date: 2021-08-12T20:10:44Z
creator: http://orcid.org/0000-0001-7941-2961

physiological support therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: Therapeutic care designed to maintain the natural processes of the body and return to a more normal state of health.
date: 2021-08-12T20:14:31Z
creator: http://orcid.org/0000-0001-7941-2961

Axiom
annotated source: physiological support therapy
annotated property: IAO_0000115
annotated target: Therapeutic care designed to maintain the natural processes of the body and return to a more normal state of health.
has db xref: NCIT:C66895

hydration therapy
type: Class
subclass of: physiological support therapy
IAO_0000115: Delivery of fluids to the body by any methods necessary.
date: 2021-08-12T20:16:16Z
creator: http://orcid.org/0000-0001-7941-2961

saline hydration
type: Class
subclass of: hydration therapy
IAO_0000115: Use of isotonic saline intravenously.
date: 2021-08-12T20:16:36Z
creator: http://orcid.org/0000-0001-7941-2961

bisphosphonate agent therapy
type: Class
subclass of: pharmacotherapy
IAO_0000115: Treatment with a set of compounds that allow osteoblasts (bone building cells) to work more effectively, improving bone mass. Bisphosphonates are used in the treatment of osteoporosis, Paget's disease of bone, and may be used to lower high calcium levels.
date: 2021-08-12T20:21:07Z
creator: http://orcid.org/0000-0001-7941-2961

bi-level positive airway pressure ventilation
type: Class
subclass of: positive controlled ventilation
IAO_0000115: Bi-level positive airway pressure (or trade name BiPAP) delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment.
date: 2021-08-13T20:17:37Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: BiPAP
comment: Two new ventilatory techniques with almost identical names have been developed for adults: BiPAP(trademark) and BIPAP. BiPAP is a trade name derived from 'bi-level positive airway pressure'. BiPAP delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment. In contrast, BIPAP (biphasic positive airway pressure) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.

Axiom
annotated source: bi-level positive airway pressure ventilation
annotated property: IAO_0000115
annotated target: Bi-level positive airway pressure (or trade name BiPAP) delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment.
has db xref: PMID:11353935

Axiom
annotated source: bi-level positive airway pressure ventilation
annotated property: hasExactSynonym
annotated target: BiPAP
has synonym type: OMO_0003000

Axiom
annotated source: bi-level positive airway pressure ventilation
annotated property: comment
annotated target: Two new ventilatory techniques with almost identical names have been developed for adults: BiPAP(trademark) and BIPAP. BiPAP is a trade name derived from 'bi-level positive airway pressure'. BiPAP delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment. In contrast, BIPAP (biphasic positive airway pressure) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.
has db xref: PMID:11353935

biphasic positive airway pressure ventilation
type: Class
subclass of: positive controlled ventilation
IAO_0000115: Biphasic positive airway pressure ventilation (BIPAP) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.
date: 2021-08-13T20:22:51Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: BIPAP
comment: Recently two new ventilatory techniques with almost identical names have been developed for adults: BiPAP(trademark) and BIPAP. BiPAP is a trade name derived from 'bi-level positive airway pressure'. BiPAP delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment. In contrast, BIPAP (biphasic positive airway pressure) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.

Axiom
annotated source: biphasic positive airway pressure ventilation
annotated property: IAO_0000115
annotated target: Biphasic positive airway pressure ventilation (BIPAP) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.
has db xref: PMID:11353935

Axiom
annotated source: biphasic positive airway pressure ventilation
annotated property: hasExactSynonym
annotated target: BIPAP
has synonym type: OMO_0003000

Axiom
annotated source: biphasic positive airway pressure ventilation
annotated property: comment
annotated target: Recently two new ventilatory techniques with almost identical names have been developed for adults: BiPAP(trademark) and BIPAP. BiPAP is a trade name derived from 'bi-level positive airway pressure'. BiPAP delivers, by mask, two levels of pressure in response to patient flow. It is intended to support ventilation in a nonin-vasive way in spontaneously but insufficiently breathing patients in the home care environment. In contrast, BIPAP (biphasic positive airway pressure) is a mode of ventilation developed for full ventilatory support in intensive care settings with the use of an endotracheal tube.
has db xref: PMID:11353935

deep sclerectomy
type: Class
subclass of: non-penetrating glaucoma surgery
IAO_0000115: A procedure where filtering membrane is created for fluid to move out of the front chamber of the eye to underneath the superficial tissues around it (conjunctiva) and thus lowering the presure of the eye.
date: 2023-02-24T17:30:45Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: NPDS
has exact synonym: non-penetrating deep sclerectomy

canaloplasty
type: Class
subclass of: viscocanalostomy
IAO_0000115: Canaloplasty is a modification of viscocanalostomy, in which an additional intracanalicular stent is inserted to maintain canal patency and enhance the circumferential flow.
date: 2023-02-24T17:31:07Z
creator: https://orcid.org/0000-0001-7941-2961

viscocanalostomy
type: Class
subclass of: deep sclerectomy
IAO_0000115: A procedure that is a variation of a deep sclerectomy procedure. This procedure involves unroofing and dilation of the Schlemm’s canal without penetrating the trabecular meshwork or anterior chamber. A high-viscosity viscoelastic solution is injected to dilate the canal and create a passage from the canal to a scleral reservoir, thereby reducing intraocular pressure.
date: 2023-02-24T17:34:27Z
creator: https://orcid.org/0000-0001-7941-2961

non-penetrating glaucoma surgery
type: Class
subclass of: glaucoma filtration surgery
IAO_0000115: A procedure to reduce intraocular pressure by enhancing the natural aqueous outflow channels, while reducing outflow resistance located in the inner wall of the Schlemm's canal and the juxtacanalicular trabecular meshwork.
date: 2023-02-24T17:51:12Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: NPGS
has exact synonym: non-penetrating filtrating surgery

glaucoma filtration surgery
type: Class
subclass of: surgical procedure on the eye
IAO_0000115: The surgery creates an alternative pathway for fluid to leave the eye. A small channel, or 'bleb' is created to allow fluid to drain from the eye.
date: 2023-02-24T17:54:23Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: filtering sugery
has exact synonym: filtrating glaucoma surgery
has exact synonym: incisional glaucoma surgery

ostomy surgical procedure
type: Class
subclass of: surgical procedure
IAO_0000115: The construction of a passage between a cavity or hollow organ to the surface of the body often to help drain bodily fluid.
date: 2023-02-27T18:00:04Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15290
has narrow synonym: construction of a stoma

posterior sagittal anorectoplasty
type: Class
subclass of: pull-through procedure
subclass of: MAXO_0001352
IAO_0000115: This technique surgically creates the patient’s anus within the sphincter muscle.
date: 2023-02-27T21:28:55Z
creator: https://orcid.org/0000-0001-7941-2961

ophthalmic diagnostic procedure
type: Class
equivalent class: Class
  intersection of: diagnostic procedure by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000970
subclass of: MAXO_0001444
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000970
IAO_0000115: A diagnostic procedure to evaluate the structure and/or function of the eye and visual system.
date: 2023-02-24T19:03:34Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: ophthalmological diagnostic procedure
has exact synonym: ophthalmology diagnostic procedure

optical coherence tomography
type: Class
subclass of: eye examination
IAO_0000115: A noninvasive imaging technique that provides high-resolution, cross-sectional images of the retina, retinal nerve fiber layer and the optic nerve head.
date: 2023-02-24T19:20:56Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: OCT

Axiom
annotated source: optical coherence tomography
annotated property: IAO_0000115
annotated target: A noninvasive imaging technique that provides high-resolution, cross-sectional images of the retina, retinal nerve fiber layer and the optic nerve head.
has db xref: PMID:23429598

gonioscopy
type: Class
subclass of: ophthalmic diagnostic procedure
IAO_0000115: An examination of the anterior chamber of the eye with a lens that is placed against the eye as a part of a slit-lamp examination.
date: 2023-02-24T19:25:28Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: slit-lamp gonioscopy

vision assessment
type: Class
subclass of: eye examination
IAO_0000115: A test to assess the ability to focus on and discern objects, colors, depth, etc.
date: 2023-02-24T19:28:40Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C156778
has exact synonym: vision screening
has exact synonym: vision test

eye movement measurement
type: Class
subclass of: eye examination
IAO_0000115: Assessment of the parameters of eye movement, including horizontal and vertical rotations of the eye, opening or closing of the eyes in response to stimuli, pupil response to light, and blink reflex.
date: 2023-02-24T19:31:14Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C162707
has exact synonym: eye movement assessment

slit-lamp examination
type: Class
subclass of: eye examination
IAO_0000115: A test performed by an ophthalmologist or optometrist assessing vision and ability to focus on and discern objects, as well as other tests and examinations pertaining to the eyes.
date: 2023-02-24T19:35:05Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C38060

tonometry
type: Class
subclass of: eye examination
IAO_0000115: A method in which pressure is applied to the surface of the cornea in order to flatten a prespecified area of the membrane, which is used to calculate intraocular pressure.
date: 2023-02-24T19:38:54Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: IOP measurement
has exact synonym: intraocular pressure measurement

applanation tonometry
type: Class
subclass of: tonometry
IAO_0000115: A method in which a constant pressure is applied to the surface of the cornea in order to flatten a prespecified area of the membrane, which is used to calculate intraocular pressure.
date: 2023-02-24T19:40:23Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C120682

rebound tonometry
type: Class
subclass of: tonometry
IAO_0000115: A method in which a probe is bounced off of the surface of the cornea, creating an induction current that is used to calculate intraocular pressure.
date: 2023-02-24T19:41:43Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C120703

pull-through procedure
type: Class
subclass of: MAXO_0001354
IAO_0000115: The surgeon makes small incisions in the abdomen in order to insert an endoscope into the body. The endoscope can either clear the blockage, or remove the portion of intestines without nerves. The healthy portions of intestines are then reconnected in order to allow stool to pass through.
date: 2023-02-27T21:33:53Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: TERPT
has exact synonym: transanal endorectal pull-through procedure
comment: This is also referred to as 'Hirschsprung disease surgery' as it is used for patients with 'Hirschsprung disease'.

laparoscopic-assisted anorectoplasty
type: Class
subclass of: pull-through procedure
subclass of: MAXO_0001352
IAO_0000115: A techniqhe which positions the neorectum accurately inside the sphincter complex without dividing any of these muscles.
date: 2023-02-27T21:48:16Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: LAARP

diagnostic procedure by site
type: Class
equivalent class: Class
  intersection of: diagnostic procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: diagnostic procedure
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001062
IAO_0000115: Procedure to evaluate the structure and/or function of a particular by part or system.
date: 2023-03-29T20:10:49Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: diagnostic procedure by body location

CT by site
type: Class
equivalent class: Class
  intersection of: computed tomography procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: computed tomography procedure
subclass of: clinical imaging procedure by system
IAO_0000115: The use of computed tomography to produce images of structures of a particular body site.
date: 2023-03-30T17:40:25Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: computed tomography procedure by body location

clinical biopsy by site
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: diagnostic procedure by site
subclass of: clinical biopsy
IAO_0000115: A specimen collection from a particular body site used for diagnostic purposes.
date: 2023-03-30T17:56:49Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: biopsy by body location

removal of nail
type: Class
subclass of: MAXO_0001416
IAO_0000115: A procedure to take off or remove part or entire nail.
date: 2023-03-31T14:53:59Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: nail removal

debridement of nail
type: Class
subclass of: removal of nail
IAO_0000115: Reduction in the thickness and length of the nail. Often used to remove thickened nails due to fungal infection.
date: 2023-03-31T14:54:13Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: nail debridement
comment: Debridement can be done by filing or drilling or other methods.

removal of skin
type: Class
subclass of: MAXO_0001417
IAO_0000115: Removal or elimination of a portion of skin for therapeutic use.
date: 2023-03-31T15:11:49Z
creator: https://orcid.org/0000-0001-7941-2961

debridement of skin
type: Class
subclass of: removal of skin
IAO_0000115: Removal of dead (necrotic) or infected skin to help a wound heal.
date: 2023-03-31T18:20:39Z
creator: https://orcid.org/0000-0001-7941-2961

desloughing of skin
type: Class
subclass of: removal of skin
IAO_0000115: Removing slough from a wound.
date: 2023-03-31T18:20:54Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: removal of slough from skin

application of emollient to skin
type: Class
subclass of: MAXO_0001417
IAO_0000115: Addition of a softening or soothing agent to the skin.
date: 2023-03-31T19:02:52Z
creator: https://orcid.org/0000-0001-7941-2961
has broad synonym: use of emollient
has exact synonym: emollient application to skin
has exact synonym: use of skin emollients

body shape assessment
type: Class
subclass of: body measurement
IAO_0000115: Determination of shape of body or body parts. This may be used to assess symmetry, number, size, and shape of a patient's body or body parts.
date: 2023-04-13T16:06:37Z
creator: https://orcid.org/0000-0001-7941-2961

facial morphology assessment
type: Class
subclass of: head morphology assessment
IAO_0000115: Determination of shape, symmetry, and/or size of face.
date: 2023-04-13T16:10:13Z
creator: https://orcid.org/0000-0001-7941-2961

head morphology assessment
type: Class
subclass of: body shape assessment
IAO_0000115: Determination of shape, symmetry, and/or size of head.
date: 2023-04-13T16:11:14Z
creator: https://orcid.org/0000-0001-7941-2961

functional magnetic resonance imaging procedure
type: Class
subclass of: magnetic resonance imaging procedure
IAO_0000115: The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function.
date: 2019-04-26T20:04:29Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C17958
has exact synonym: Functional MRI
has exact synonym: fMRI

Axiom
annotated source: functional magnetic resonance imaging procedure
annotated property: IAO_0000115
annotated target: The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function.
has db xref: NCIT:C17958

Axiom
annotated source: functional magnetic resonance imaging procedure
annotated property: hasExactSynonym
annotated target: Functional MRI
has synonym type: OMO_0003000

Axiom
annotated source: functional magnetic resonance imaging procedure
annotated property: hasExactSynonym
annotated target: fMRI
has synonym type: OMO_0003000

gene therapy
type: Class
subclass of: biologic therapy
IAO_0000115: Gene therapy involves the use of nucleic acids (DNA or RNA) for the treatment, cure or prevention of human disorders.
date: 2019-05-07T16:28:50Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15238
has db xref: SCDO:0001344
has exact synonym: DNA therapy
has exact synonym: gene therapies
has exact synonym: gene transfer procedure
has exact synonym: genetic therapy

Axiom
annotated source: gene therapy
annotated property: IAO_0000115
annotated target: Gene therapy involves the use of nucleic acids (DNA or RNA) for the treatment, cure or prevention of human disorders.
has db xref: PMID:24106209

immunotherapy procedure
type: Class
subclass of: biologic therapy
IAO_0000115: The goal of immunotherapy is to induce anti-disease (usually tumor) responses by reprogramming and augmenting immune surveillance, and reducing immune suppression.
date: 2019-05-07T16:32:45Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C15262
has db xref: OGMS:0000114
has exact synonym: immune therapy
has exact synonym: immunologically directed therapy

Axiom
annotated source: immunotherapy procedure
annotated property: IAO_0000115
annotated target: The goal of immunotherapy is to induce anti-disease (usually tumor) responses by reprogramming and augmenting immune surveillance, and reducing immune suppression.
has db xref: PMID:29242097

alcohol deterrent agent therapy
type: Class
subclass of: abuse deterrent agent therapy
IAO_0000115: Treatment with a drug that deters or encourages the cessation of drinking alcohol.
date: 2019-05-15T16:33:57Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: alcohol deterrent drug treatment

smoking cessation agent therapy
type: Class
subclass of: abuse deterrent agent therapy
IAO_0000115: Treatment with a drug that deters smoking or encourages the cessation of smoking tobacco.
date: 2019-05-15T16:44:49Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: smoking cessation drug treatment

opioid antagonist agent therapy
type: Class
subclass of: toxicologic agent therapy
IAO_0000115: An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists.
date: 2019-05-15T16:45:09Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:60605
has db xref: NCIT:C681
has exact synonym: opiate antagonist agent therapy
has exact synonym: opioid antagonist drug treatment

Axiom
annotated source: opioid antagonist agent therapy
annotated property: IAO_0000115
annotated target: An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists.
has db xref: CHEBI:60605

obsolete hematopoeitic cell count
type: Class
IAO_0100001: MAXO_0001509
deprecated: true

erythrocyte count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000232
subclass of: MAXO_0001509
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000232
IAO_0000115: A determination of the number of erythrocyte in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C51946
has exact synonym: erythrocyte count test
has exact synonym: red blood cell count
has exact synonym: red cell count

platelet count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000233
subclass of: MAXO_0001509
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000233
IAO_0000115: A determination of the number of platelet in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C51951
has exact synonym: platelet count test
has exact synonym: thrombocyte count

neutrophil count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000775
subclass of: granulocyte count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000775
IAO_0000115: A determination of the number of neutrophil in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has exact synonym: neutrophil count test

leukocyte count
type: Class
equivalent class: Class
  intersection of: clinical cell count
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PATO_0000070
      intersection of: Restriction
        on property: RO_0000052
        some values from: CL_0000738
subclass of: clinical cell count
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000738
IAO_0000115: A determination of the number of leukocyte in a blood sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-16T18:20:55Z
has db xref: NCIT:C51948
has exact synonym: WBC
has exact synonym: leukocyte count test
has exact synonym: white blood cell count

Axiom
annotated source: leukocyte count
annotated property: hasExactSynonym
annotated target: WBC
has synonym type: OMO_0003000

body measurement
type: Class
subclass of: clinical assessment
IAO_0000115: Measuring the body or its parts.
date: 2023-04-13T16:22:35Z
creator: https://orcid.org/0000-0001-7941-2961

waist measurement
type: Class
subclass of: body measurement
IAO_0000115: Measuring the distance around (circumference) a patient's waist.
date: 2023-04-13T16:49:17Z
creator: https://orcid.org/0000-0001-7941-2961

hip measurement
type: Class
subclass of: body measurement
IAO_0000115: A measurement of circumference around the hip.
date: 2023-04-13T16:49:27Z
creator: https://orcid.org/0000-0001-7941-2961

medical action avoidance
type: Class
subclass of: medical action
subclass of: Restriction
  on property: avoided medical action
  some values from: medical action
IAO_0000115: A recommendation of abstaining or avoiding any medical action that might normally be clinically prescribed.
date: 2019-06-12T14:22:47Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: avoid medical action recommendation
has exact synonym: avoidance of a medical action

aerobic exercise therapy avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: aerobic exercise therapy
IAO_0000115: Avoid the administration or use of aerobic exercise therapy.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2019-05-19T20:39:14Z
has exact synonym: avoid aerobic exercise therapy
has exact synonym: avoiding aerobic exercise therapy

vaccination
type: Class
subclass of: active immunization
IAO_0000115: Inoculating an individual with either killed or live agents to prevent contraction of a disease.
date: 2019-06-14T15:47:12Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: EFO:0004292
has db xref: IDOMAL:0001040
has db xref: NCIT:C15258
has db xref: VO:0000002

Axiom
annotated source: vaccination
annotated property: IAO_0000115
annotated target: Inoculating an individual with either killed or live agents to prevent contraction of a disease.
has db xref: NCIT:C15258

nutrition intake
type: Class
subclass of: nutrition intervention
IAO_0000115: Nutrition intake is the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.
date: 2019-07-23T18:14:54Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: nutrient consumption
has exact synonym: nutrient intake
has exact synonym: nutrition consumption
has exact synonym: nutritional intake
has exact synonym: take nourishment
has narrow synonym: dietary intake
has narrow synonym: eating
has narrow synonym: food consumption
has narrow synonym: food intake
has narrow synonym: ingesting

Axiom
annotated source: nutrition intake
annotated property: IAO_0000115
annotated target: Nutrition intake is the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.
has db xref: https://orcid.org/0000-0001-7941-2961

prenatal vitamin supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: FOODON_03310664
subclass of: multivitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: FOODON_03310664
IAO_0000115: Addition of vitamin supplement, prenatal to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has db xref: NCIT:C92860
has exact synonym: antenatal supplementation
has exact synonym: antenatal vitamin supplement treatment
has exact synonym: antenatal vitamin treatment
has exact synonym: dietary supplementation of vitamin supplement, prenatal
has exact synonym: prenatal vitamin supplement treatment
has exact synonym: supplementation of vitamin supplement, prenatal
has exact synonym: supplementation with prenatal vitamin
has exact synonym: treatment with prenatal supplements
has exact synonym: vitamin supplement, prenatal supplemental intake
comment: A vitamin enriched supplement containing higher doses for specific nutrients such as folic acid, intended for women before, during and after pregnancy and also during their lactating phase.

Axiom
annotated source: prenatal vitamin supplementation
annotated property: comment
annotated target: A vitamin enriched supplement containing higher doses for specific nutrients such as folic acid, intended for women before, during and after pregnancy and also during their lactating phase.
has db xref: NCIT:C92860

general anesthetic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38869
subclass of: anesthetic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38869
IAO_0000115: A therapy utilizing a substance that produces loss of consciousness.
date: 2019-07-24T15:53:13Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:38869
has exact synonym: general anaesthetic agents therapy
has exact synonym: general anaesthetic medication therapy
has exact synonym: general anaesthetics therapy
has exact synonym: general anesthesia therapy
has exact synonym: general anesthesia treatment
has exact synonym: general anesthetic medication therapy
has exact synonym: general anesthetics therapy
has exact synonym: treatment with general anaesthetic

antimicrobial agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_36043
subclass of: anti-infective agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_36043
IAO_0000115: Use of a drug or therapy to treat or prevent microbial infections.
date: 2019-07-24T16:13:47Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:36043
has exact synonym: antimicrobial drug treatment
has exact synonym: antimicrobial treatment
has exact synonym: treatment with an anti-microbial agent
has exact synonym: treatment with an anti-microbial drug
has exact synonym: treatment with an anti-microbial medication
has exact synonym: treatment with an antimicrobial agent
has exact synonym: treatment with an antimicrobial drug
has exact synonym: treatment with an antimicrobial medication
has exact synonym: treatment with antimicrobial drug

psychotropic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35471
subclass of: central nervous system agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35471
IAO_0000115: Use of a loosely defined grouping of drugs that have effects on psychological function.
date: 2019-07-24T19:33:44Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35471
has exact synonym: psychoactive agent therapy
has exact synonym: psychoactive drug treatment
has exact synonym: psychopharmaceutical therapy
has exact synonym: psychotropic agent drug therapy
has exact synonym: psychotropic drug treatment
has exact synonym: treatment with psychotropic drug

obsolete tranquilizing agent therapy
type: Class
IAO_0100001: mood and behavior-altering agent therapy
deprecated: true

waist to hip ratio calculation
type: Class
subclass of: body measurement
IAO_0000115: A ratio determined by waist measurement divided by hip measurement.
date: 2023-04-13T16:50:13Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: waist to hip ratio measurement

adrenergic drug therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37962
subclass of: cardiovascular agent therapy
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_37962
IAO_0000115: Therapy using any agent that acts on an adrenergic receptor or affects adrenergic signal transduction.
date: 2019-07-25T14:32:48Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:37962
has db xref: NCIT:C29747
has exact synonym: adrenergic agent drug treatment
has exact synonym: treatment with adrenergic agent
has exact synonym: treatment with adrenergic drug
has exact synonym: treatment with adrenergic medication

beta-adrenergic agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35522
subclass of: beta adrenergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35522
IAO_0000115: Treatment with an agent that selectively binds to and activates beta-adrenergic receptors.
date: 2019-07-25T14:42:00Z
creator: http://orcid.org/0000-0001-7941-2961
has db xref: CHEBI:35522
has exact synonym: treatment with beta-adrenergic agonist
has exact synonym: treatment with beta-adrenergic agonist agent
has exact synonym: treatment with beta-adrenergic agonist drug
has exact synonym: treatment with beta-adrenergic agonist medication

facial morphology assessment by type
type: Class
subclass of: facial morphology assessment
IAO_0000115: Determination of shape, symmetry, and/or size of face using a particular method.
date: 2023-04-13T16:53:56Z
creator: https://orcid.org/0000-0001-7941-2961

adenoidectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001732
subclass of: surgical excision
subclass of: MAXO_0001423
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001732
IAO_0000115: The surgical removal (cutting out) of part or all of pharyngeal tonsil.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51697
has exact synonym: adenoid removal
has exact synonym: pharyngeal tonsil surgical removal
has exact synonym: removal of adenoids
has exact synonym: removal of nasopharyngeal tonsil
has exact synonym: removal of tonsil of Luschka
has exact synonym: removal of tonsilla pharyngealis

adrenalectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002369
subclass of: adenectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002369
IAO_0000115: The surgical removal (cutting out) of part or all of adrenal gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: adrenal gland surgical removal

apicoectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003677
subclass of: surgical excision
subclass of: orthopedic surgery
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003677
IAO_0000115: The surgical removal (cutting out) of part or all of tooth root.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: tooth root surgical removal

appendectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001154
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001504
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001154
IAO_0000115: The surgical removal (cutting out) of part or all of vermiform appendix.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51687
has exact synonym: appendicectomy
has exact synonym: appendix removal
has exact synonym: removal of appendix
has exact synonym: vermiform appendix surgical removal

arthectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000982
subclass of: surgical excision
subclass of: orthopedic surgery
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000982
IAO_0000115: The surgical removal (cutting out) of part or all of skeletal joint.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: removal of a joint
has exact synonym: skeletal joint surgical removal

auriculectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001690
subclass of: surgery by body site
subclass of: cephalectomy
subclass of: MAXO_0001422
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001690
IAO_0000115: The surgical removal (cutting out) of part or all of ear.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: ear surgical removal

bursectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003668
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003668
IAO_0000115: The surgical removal (cutting out) of part or all of synovial bursa.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: bursa removal
has exact synonym: removal of bursa
has exact synonym: synovial bursa surgical removal

gastric cardiectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001162
subclass of: gastrectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001162
IAO_0000115: The surgical removal (cutting out) of part or all of cardia of stomach.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: cardia of stomach surgical removal
has exact synonym: cardiectomy
has exact synonym: cardiectomy of stomach

cephalectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000033
subclass of: therapeutic procedure by site
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000033
IAO_0000115: The surgical removal (cutting out) of part or all of head.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: decapitation
has exact synonym: head surgical removal

cervicectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000002
subclass of: hysterectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000002
IAO_0000115: The surgical removal (cutting out) of part or all of uterine cervix.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: cervix removal
has exact synonym: removal of cervix
has exact synonym: uterine cervix surgical removal

cholecystectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002110
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002110
IAO_0000115: The surgical removal (cutting out) of part or all of gallbladder.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51676
has exact synonym: gallbladder surgical removal

choroidectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001776
subclass of: surgical procedure on the eye
subclass of: cephalectomy
subclass of: MAXO_0001515
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001776
IAO_0000115: The surgical removal (cutting out) of part or all of optic choroid.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: optic choroid surgical removal
has exact synonym: removal of choroid layer of they eye

clitoridectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002411
subclass of: vulvectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002411
IAO_0000115: The surgical removal (cutting out) of part or all of clitoris.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: clitorectomy
has exact synonym: clitoris surgical removal

colectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001155
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001504
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001155
IAO_0000115: The surgical removal (cutting out) of part or all of colon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C15209
has exact synonym: colon surgical removal

craniectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003128
subclass of: surgical excision
subclass of: orthopedic surgery
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003128
IAO_0000115: The surgical removal (cutting out) of part or all of cranium.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51791
has exact synonym: cranium surgical removal

cystectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001255
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001412
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001255
IAO_0000115: The surgical removal (cutting out) of part or all of urinary bladder.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C15217
has exact synonym: bladder removal
has exact synonym: removal of the bladder
has exact synonym: urinary bladder surgical removal
comment: Can mean the removal of the urinary bladder or the surgical removal of a cyst.

corpectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001075
subclass of: laminectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001075
IAO_0000115: The surgical removal (cutting out) of part or all of bony vertebral centrum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: body of vertebrae removal
has exact synonym: bony vertebral centrum surgical removal
has exact synonym: corpus vertebra removal
has exact synonym: corpus vertebrae removal
has exact synonym: vertebral body removal
has exact synonym: vertebrectomy

discectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001066
subclass of: arthectomy
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001066
IAO_0000115: The surgical removal (cutting out) of part or all of intervertebral disk.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C21009
has exact synonym: intervertebral disk surgical removal
has exact synonym: removal of intervertebral disc
has exact synonym: removal of spinal disc

digestive tract diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0009854
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0009854
IAO_0000115: The surgical removal (cutting out) of part or all of digestive tract diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: digestive tract diverticulum surgical removal

thyroid diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0007689
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007689
IAO_0000115: The surgical removal (cutting out) of part or all of thyroid diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: thyroid diverticulum surgical removal

hepatic diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0008835
subclass of: digestive tract diverticulectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0008835
IAO_0000115: The surgical removal (cutting out) of part or all of hepatic diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: hepatic diverticulum surgical removal

duodenectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002114
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002114
IAO_0000115: The surgical removal (cutting out) of part or all of duodenum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: duodenum surgical removal
has exact synonym: enterectomy
has exact synonym: pancreas-sparing duodenectomy
has exact synonym: small bowel resection

endoscopic thoracic sympathectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004295
subclass of: neurectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004295
IAO_0000115: The surgical removal (cutting out) of part or all of sympathetic nerve trunk.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: sympathetic nerve trunk surgical removal

esophagectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001043
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001043
IAO_0000115: The surgical removal (cutting out) of part or all of esophagus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: esophagus surgical removal
has exact synonym: oesophagectomy

gastrectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000945
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001504
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000945
IAO_0000115: The surgical removal (cutting out) of part or all of stomach.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: stomach surgical removal

glossectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001723
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001723
IAO_0000115: The surgical removal (cutting out) of part or all of tongue.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: tongue surgical removal

gonadectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000991
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000991
IAO_0000115: The surgical removal (cutting out) of part or all of gonad.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: gonad surgical removal

hepatectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002107
subclass of: adenectomy
subclass of: MAXO_0001413
subclass of: MAXO_0001503
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
IAO_0000115: The surgical removal (cutting out) of part or all of liver.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: liver surgical removal

hypophysectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000007
subclass of: surgical procedure on nervous system
subclass of: adenectomy
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000007
IAO_0000115: The surgical removal (cutting out) of part or all of pituitary gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: hypophysis removal
has exact synonym: pituitary gland surgical removal

hysterectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000995
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000995
IAO_0000115: The surgical removal (cutting out) of part or all of uterus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: uterus surgical removal

iridectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001769
subclass of: surgical procedure on the eye
subclass of: cephalectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001769
IAO_0000115: The surgical removal (cutting out) of part or all of iris.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: iris surgical removal

keratectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000964
subclass of: surgical procedure on the eye
subclass of: cephalectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000964
IAO_0000115: The surgical removal (cutting out) of part or all of cornea.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: cornea surgical removal

laminectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002412
subclass of: surgical excision
subclass of: orthopedic surgery
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002412
IAO_0000115: The surgical removal (cutting out) of part or all of vertebra.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: vertebra surgical removal

laryngectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001737
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001737
IAO_0000115: The surgical removal (cutting out) of part or all of larynx.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: larynx surgical removal
has exact synonym: lymph node dissection

lymphadenectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000029
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001423
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000029
IAO_0000115: The surgical removal (cutting out) of part or all of lymph node.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: lymph node surgical removal

mastectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000310
subclass of: therapeutic procedure by site
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000310
IAO_0000115: The surgical removal (cutting out) of part or all of breast.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: breast surgical removal

nephrectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002113
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
IAO_0000115: The surgical removal (cutting out) of part or all of kidney.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: kidney surgical removal

neurectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001021
subclass of: surgical excision
subclass of: surgical procedure on nervous system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001021
IAO_0000115: The surgical removal (cutting out) of part or all of nerve.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: nerve surgical removal

oophorectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000992
subclass of: gonadectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000992
IAO_0000115: The surgical removal (cutting out) of part or all of ovary.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: female gonad removal
has exact synonym: ovariectomy
has exact synonym: ovary surgical removal
has exact synonym: removal of female genitalia
has exact synonym: removal of female gonad
has exact synonym: removal of female reproductive system gonada
has exact synonym: removal of gonada of female

orchiectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000473
subclass of: gonadectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000473
IAO_0000115: The surgical removal (cutting out) of part or all of testis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: castration
has exact synonym: orchidectomy
has exact synonym: removal of male genitalia gonad
has exact synonym: removal of testicles
has exact synonym: testis surgical removal

ostectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002481
subclass of: surgical excision
subclass of: orthopedic surgery
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002481
IAO_0000115: The surgical removal (cutting out) of part or all of bone tissue.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: bone tissue surgical removal

pancreatectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001264
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
IAO_0000115: The surgical removal (cutting out) of part or all of pancreas.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: pancreas surgical removal

abdominal panniculectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0013488
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001416
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0013488
IAO_0000115: The surgical removal (cutting out) of part or all of panniculus adiposus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51597
has exact synonym: panniculus adiposus surgical removal

parathyroidectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001132
subclass of: adenectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001132
IAO_0000115: The surgical removal (cutting out) of part or all of parathyroid gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: parathyroid gland surgical removal
has exact synonym: parathyroid removal

pinealectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001905
subclass of: surgical procedure on nervous system
subclass of: adenectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001905
IAO_0000115: The surgical removal (cutting out) of part or all of pineal body.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: pineal body surgical removal
has exact synonym: removal of pineal gland

pneumonectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002048
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002048
IAO_0000115: The surgical removal (cutting out) of part or all of lung.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: lung surgical removal
has exact synonym: pneumectomy

posthectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001471
subclass of: penectomy
subclass of: MAXO_0001468
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001471
IAO_0000115: The surgical removal (cutting out) of part or all of skin of prepuce of penis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: circumcision
has exact synonym: forskin removal
has exact synonym: skin of prepuce of penis surgical removal

salpingectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003889
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003889
IAO_0000115: The surgical removal (cutting out) of part or all of fallopian tube.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: fallopian tube surgical removal

splenectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002106
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001415
subclass of: MAXO_0001423
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002106
IAO_0000115: The surgical removal (cutting out) of part or all of spleen.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: spleen surgical removal

synovectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002018
subclass of: arthectomy
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002018
IAO_0000115: The surgical removal (cutting out) of part or all of synovial membrane of synovial joint.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: synovial membrane of synovial joint surgical removal

thymectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002370
subclass of: adenectomy
subclass of: MAXO_0001415
subclass of: MAXO_0001423
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
IAO_0000115: The surgical removal (cutting out) of part or all of thymus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: thymus surgical removal

thyroidectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002046
subclass of: adenectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002046
IAO_0000115: The surgical removal (cutting out) of part or all of thyroid gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: thyroid gland surgical removal

tonsillectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002373
subclass of: surgical excision
subclass of: MAXO_0001423
subclass of: MAXO_0001443
subclass of: MAXO_0001503
subclass of: MAXO_0001514
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002373
IAO_0000115: The surgical removal (cutting out) of part or all of palatine tonsil.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: palatine tonsil surgical removal

trabeculectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0005969
subclass of: glaucoma filtration surgery
subclass of: cephalectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0005969
IAO_0000115: A surgical procedure aimed at lowering the intraocular pressure by producing an outflow of aqueous humour through a drainage passage created in the sclera between the anterior chamber and the subconjunctival space.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:12:12Z
has exact synonym: eye trabecular meshwork surgical removal
comment: The filtering procedure involves full thickness penetration of sclera to remove a small portion of the trabecular meshwork or surrounding tissue; it bypasses the natural outflow system by diverting aqueous humor from the anterior chamber into a subconjunctival reservoir with a filtering bleb on the eye. Antifibrotic agents, such as mitomycin-C and 5-fluorouracil, may be used intraoperatively and postoperatively to reduce scarring and prevent closure of the new channel.

vaginectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000996
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000996
IAO_0000115: The surgical removal (cutting out) of part or all of vagina.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: vagina surgical removal

vasectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001000
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001000
IAO_0000115: The surgical removal (cutting out) of part or all of vas deferens.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: vas deferens surgical removal

vitrectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001797
subclass of: surgical procedure on the eye
subclass of: cephalectomy
subclass of: MAXO_0001433
IAO_0000115: The surgical removal (cutting out) of part or all of vitreous humor.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: vitreous humor surgical removal

vulvectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000997
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000997
IAO_0000115: The surgical removal (cutting out) of part or all of mammalian vulva.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: mammalian vulva surgical removal

penectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000989
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000989
IAO_0000115: The surgical removal (cutting out) of part or all of penis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: penis surgical removal

bullectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0032446
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0032446
IAO_0000115: The surgical removal (cutting out) of part or all of Pulmonary bulla.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Pulmonary bulla surgical removal

bunionectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0001822
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0001822
IAO_0000115: The surgical removal (cutting out) of part or all of Hallux valgus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C96171
has exact synonym: Hallux valgus surgical removal
has exact synonym: bunion removal
has exact synonym: removal of bunion

3D facial analysis
type: Class
subclass of: clinical imaging procedure
subclass of: facial morphology assessment by type
IAO_0000115: Computer aided analysis of 3D facial images to detect abnormal facial phenotypes that assist in diagnosis, treatment monitoring and surgical planning.
date: 2023-04-13T16:54:13Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: '3D facial assessment'
has exact synonym: three dimensional facial analysis
has exact synonym: three dimensional facial assessment

Axiom
annotated source: 3D facial analysis
annotated property: IAO_0000115
annotated target: Computer aided analysis of 3D facial images to detect abnormal facial phenotypes that assist in diagnosis, treatment monitoring and surgical planning.
has db xref: PMID:34108542

Meckel's diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0002245
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0002245
IAO_0000115: Surgical removal of an abnormal pouch of the lining of the small intestine (bowel).
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Meckel diverticulum surgical removal

cardiac diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100571
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100571
IAO_0000115: The surgical removal (cutting out) of part or all of Cardiac diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Cardiac diverticulum surgical removal

esophageal diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100628
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100628
IAO_0000115: The surgical removal (cutting out) of part or all of Esophageal diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Esophageal diverticulum surgical removal

gastric diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100808
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100808
IAO_0000115: The surgical removal (cutting out) of part or all of Gastric diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Gastric diverticulum surgical removal

renal diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100877
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100877
IAO_0000115: The surgical removal (cutting out) of part or all of Renal diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Renal diverticulum surgical removal

bladder diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0000015
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0000015
IAO_0000115: The surgical removal (cutting out) of part or all of Bladder diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Bladder diverticulum surgical removal

uethral diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0008722
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0008722
IAO_0000115: The surgical removal (cutting out) of part or all of Urethral diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Urethral diverticulum surgical removal

fibrous cardiac diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100572
subclass of: cardiac diverticulectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100572
IAO_0000115: The surgical removal (cutting out) of part or all of Fibrous cardiac diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Fibrous cardiac diverticulum surgical removal

muscular cardiac diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100573
subclass of: cardiac diverticulectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100573
IAO_0000115: The surgical removal (cutting out) of part or all of Muscular cardiac diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Muscular cardiac diverticulum surgical removal

spinal meningeal diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0010304
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0010304
IAO_0000115: The surgical removal (cutting out) of part or all of Spinal meningeal diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Spinal meningeal diverticulum surgical removal

coronary sinus diverticulectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0011644
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0011644
IAO_0000115: The surgical removal (cutting out) of part or all of Coronary sinus diverticulum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Coronary sinus diverticulum surgical removal

thromboembolectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0001907
subclass of: thrombosis
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0001907
IAO_0000115: The surgical removal (cutting out) of part or all of Thromboembolism.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Thromboembolism surgical removal

pulmonary embolectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0002204
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0002204
IAO_0000115: The surgical removal (cutting out) of part or all of Pulmonary embolism.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Pulmonary embolism surgical removal

endarterectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0003207
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0003207
IAO_0000115: The surgical removal (cutting out) of part or all of Arterial calcification.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C52002
has exact synonym: Arterial calcification surgical removal

lumpectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100013
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100013
IAO_0000115: The surgical removal (cutting out) of part or all of Neoplasm of the breast.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C15755
has exact synonym: Neoplasm of the breast surgical removal
has exact synonym: breast segmental resection
has exact synonym: breast wide local
has exact synonym: lumpectomy of breast excision
has exact synonym: partial mastectomy
has exact synonym: tylectomy
comment: Surgery to remove abnormal tissue or cancer from the breast and a small amount of normal tissue around it. It is a type of breast-sparing surgery. NCIT:C15755

myomectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0000131
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0000131
IAO_0000115: The surgical removal (cutting out) of part or all of Uterine leiomyoma.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has db xref: NCIT:C51645
has exact synonym: Uterine leiomyoma surgical removal
has exact synonym: fiboroidectomy
has exact synonym: removal of uterine fibroids

arterial thrombosis
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0004420
subclass of: thrombosis
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0004420
IAO_0000115: The surgical removal (cutting out) of part or all of Arterial thrombosis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Arterial thrombosis surgical removal

venous thrombosis
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0004936
subclass of: thrombosis
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0004936
IAO_0000115: The surgical removal (cutting out) of part or all of Venous thrombosis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Venous thrombosis surgical removal

thrombosis
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0001977
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0001977
IAO_0000115: The surgical removal (cutting out) of part or all of Abnormal thrombosis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Abnormal thrombosis surgical removal
has exact synonym: removal of thrombosis
has exact synonym: thrombosis removal

tumorectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0002664
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0002664
IAO_0000115: The surgical removal (cutting out) of part or all of Neoplasm.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has broad synonym: cancer surgery
has db xref: NCIT:C157740
has exact synonym: Neoplasm surgical removal
has exact synonym: cancer removal
has exact synonym: removal of tumor
has exact synonym: tumor removal

adenectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002530
subclass of: surgery by body site
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002530
IAO_0000115: The surgical removal (cutting out) of part or all of gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-23T20:39:14Z
has exact synonym: gland surgical removal

obsolete kidney ct
type: Class
deprecated: true

prevention of abnormal physiologic state
type: Class
equivalent class: Class
  intersection of: preventative therapy
  intersection of: Restriction
    on property: avoided behavior
    some values from: HP_0001944
subclass of: preventative therapy
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001944
IAO_0000115: A medical requirement or recommendation of avoiding or preventing abnormal physiologic state.
date: 2020-09-15T11:00:00Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: avoid physiologic state recommendation
has exact synonym: prevent physiologic state avoidance
has exact synonym: prevent physiologic state recommendation

ketosis prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001946
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Ketosis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Ketosis avoidance
has exact synonym: avoid Ketosis recommendation

Diabetes mellitus prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0000819
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Diabetes mellitus.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Diabetes mellitus avoidance
has exact synonym: avoid Diabetes mellitus recommendation

fever prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001945
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Fever.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Fever avoidance
has exact synonym: avoid Fever recommendation

seizure prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001250
IAO_0000115: Recommendation to avoid triggers known to cause seizures or take medicine to avoid seizures.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Seizure avoidance
has exact synonym: avoid Seizure recommendation

hypotension prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0002615
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Hypotension.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Hypotension avoidance
has exact synonym: avoid Hypotension recommendation

hyperglycemia prevention recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0003074
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Hyperglycemia.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Hyperglycemia avoidance
has exact synonym: avoid Hyperglycemia recommendation

weight loss avoidance recommendation
type: Class
subclass of: prevention of abnormal physiologic state
subclass of: Restriction
  on property: avoided behavior
  some values from: HP_0001824
IAO_0000115: A medical requirement or recommendation of avoiding or preventing Weight loss.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-09-15T11:00:00Z
has exact synonym: Weight loss avoidance
has exact synonym: avoid Weight loss recommendation

biopsy of kidney
type: Class
equivalent class: Class
  intersection of: clinical biopsy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002113
subclass of: biopsy of abdomen
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
IAO_0000115: Removal and examination of tissue, cells, or fluids from kidney for the purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: kidney biopsy

kidney CT
type: Class
equivalent class: Class
  intersection of: CT by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002113
subclass of: MAXO_0001467
subclass of: MAXO_0010311
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
IAO_0000115: The use of computed tomography to produce images of structures of the kidney.
dcterms creator: http://orcid.org/0000-0001-7941-3010
date: 2020-06-09T20:39:14Z
has exact synonym: CAT scan of kidney
has exact synonym: CT of kidney
has exact synonym: kidney CAT scan
has exact synonym: kidney CT examination
has exact synonym: kidney computed tomography
has exact synonym: kidney computerized axial tomography
has exact synonym: renal CAT scan
has exact synonym: renal CT

potassium supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_26216
subclass of: macronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_26216
IAO_0000115: Addition of potassium atom to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-17T02:36:00Z
has exact synonym: dietary supplementation of potassium
has exact synonym: dietary supplementation of potassium atom
has exact synonym: potassium atom supplemental intake
has exact synonym: supplementation of potassium
has exact synonym: supplementation of potassium atom

anticholesteric agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35821
subclass of: dyslipidemic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35821
IAO_0000115: Treatment with any agent that lowers cholesterol.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-17T11:00:00Z
has exact synonym: antihypercholesterolemic agent therapy
has exact synonym: cholesterol inhibitor therapy
has exact synonym: hypocholesteremic agent therapy
has exact synonym: treatment with anticholesteremic drug

loop diuretic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_77608
subclass of: diuretic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_77608
IAO_0000115: Therapy with an agent that inhibits the function of the sodium-potassium-chloride (Na+, K+, Cl-) cotransporter system in the thick ascending limb of the loop of Henle, thereby inhibiting the reabsorption of sodium, potassium, and chloride ions. This leads to an increase in the excretion of sodium, potassium, chloride, calcium, magnesium, ammonium and water.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-17T11:00:00Z
has exact synonym: treatment with loop diuretic

blood transfusion avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: blood transfusion
IAO_0000115: Avoid the administration or use of blood transfusion.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-19T20:39:14Z
has exact synonym: avoid blood transfusion
has exact synonym: avoiding blood transfusion

radiograph imaging procedure avoidance
type: Class
subclass of: medical action avoidance
subclass of: Restriction
  on property: avoided medical action
  some values from: radiograph imaging procedure
IAO_0000115: Avoid the administration or use of radiograph imaging procedure.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-19T20:39:14Z
has exact synonym: avoid radiograph imaging procedure
has exact synonym: avoiding radiograph imaging procedure

folic acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27470
subclass of: B vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27470
IAO_0000115: Addition of folic acid to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of folic acid
has exact synonym: folic acid supplemental intake
has exact synonym: supplementation of folic acid

vitamin supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_33229
subclass of: micronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_33229
IAO_0000115: Addition of vitamin (role) to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of vitamin (role)
has exact synonym: supplementation of vitamin (role)
has exact synonym: supplementation with a vitamin
has exact synonym: vitamin (role) supplemental intake

nicotinic acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_15940
subclass of: B vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_15940
IAO_0000115: Addition of nicotinic acid to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of nicotinic acid
has exact synonym: niacin supplementation
has exact synonym: nicotinic acid supplemental intake
has exact synonym: supplementation of nicotinic acid

pyridoxine supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_16709
subclass of: MAXO_0010017
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_16709
IAO_0000115: Addition of pyridoxine to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of pyridoxine
has exact synonym: pyridoxine supplemental intake
has exact synonym: supplementation of pyridoxine

obsolete dietary purine intake avoidance
type: Class
IAO_0100001: MAXO_0010108
deprecated: true

ascorbic acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_22652
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_22652
IAO_0000115: Addition of ascorbic acid to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: ascorbic acid supplemental intake
has exact synonym: dietary supplementation of ascorbic acid
has exact synonym: supplementation of ascorbic acid

sodium pyruvate supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_50144
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_50144
IAO_0000115: Addition of sodium pyruvate to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of sodium pyruvate
has exact synonym: sodium pyruvate supplemental intake
has exact synonym: supplementation of sodium pyruvate

fat-soluble vitamin supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_24020
subclass of: vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_24020
IAO_0000115: Addition of fat-soluble vitamin (role) to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-09-07T09:00:01Z
has exact synonym: dietary supplementation of fat-soluble vitamin (role)
has exact synonym: fat soluble vitamin supplementation
has exact synonym: fat-soluble vitamin (role) supplemental intake
has exact synonym: supplementation of fat-soluble vitamin (role)
has exact synonym: supplementation with fat-soluble vitamin

S-adenosyl methionine supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_15414
subclass of: micronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_15414
IAO_0000115: Addition of S-adenosyl-L-methionine to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: S-adenosyl-L-methionine supplemental intake
has exact synonym: SAM-e supplementation
has exact synonym: dietary supplementation of S-adenosyl-L-methionine
has exact synonym: supplementation of S-adenosyl-L-methionine

isoleucine supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_24898
subclass of: MAXO_0010020
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_24898
IAO_0000115: Addition of isoleucine to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of isoleucine
has exact synonym: isoleucine supplemental intake
has exact synonym: supplementation of isoleucine

valine supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27266
subclass of: MAXO_0010020
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27266
IAO_0000115: Addition of valine to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of valine
has exact synonym: supplementation of valine
has exact synonym: valine supplemental intake

calcium supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_22984
subclass of: macronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_22984
IAO_0000115: Addition of calcium atom to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: calcium atom supplemental intake
has exact synonym: dietary supplementation of calcium atom
has exact synonym: supplementation of calcium atom
has exact synonym: supplementation with calcium

calcium carbonate supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI 3311
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI 3311
IAO_0000115: Addition of calcium carbonate to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: calcium carbonate supplemental intake
has exact synonym: dietary supplementation of calcium carbonate
has exact synonym: supplementation of calcium carbonate

glucose supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_17234
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_17234
IAO_0000115: Addition of glucose to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of glucose
has exact synonym: glucose supplemental intake
has exact synonym: supplementation of glucose

docosahexaenoic acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_36005
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_36005
IAO_0000115: Addition of docosahexaenoic acid to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: DHA supplementtion
has exact synonym: dietary supplementation of docosahexaenoic acid
has exact synonym: docosahexaenoic acid supplemental intake
has exact synonym: supplementation of docosahexaenoic acid
has exact synonym: supplementation with DHA

omega-3 fatty acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_25681
subclass of: MAXO_0010024
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_25681
IAO_0000115: Addition of omega-3 fatty acid to the diet for complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of omega-3 fatty acid
has exact synonym: eicosapentaenoic acid supplementation
has exact synonym: omega-3 fatty acid supplemental intake
has exact synonym: supplementation of omega-3 fatty acid

lutein supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_28838
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_28838
IAO_0000115: Addition of lutein to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of lutein
has exact synonym: lutein supplemental intake
has exact synonym: supplementation of lutein

ribose supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_33942
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_33942
IAO_0000115: Addition of ribose to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of ribose
has exact synonym: ribose supplemental intake
has exact synonym: supplementation of ribose

fluoride supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_17051
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_17051
IAO_0000115: Addition of fluoride to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of fluoride
has exact synonym: fluoride supplemental intake
has exact synonym: supplementation of fluoride

soluble fiber supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: FOODON_03401328
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: FOODON_03401328
IAO_0000115: Addition of dietary supplement, fibre to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplement, fibre supplemental intake
has exact synonym: dietary supplementation of dietary supplement, fibre
has exact synonym: supplementation of dietary supplement, fibre
has exact synonym: supplementation with soluble fiber

fish oil supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: FOODON_03306123
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: FOODON_03306123
IAO_0000115: Addition of fish oil to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-23T09:00:01Z
has exact synonym: dietary supplementation of fish oil
has exact synonym: fish oil supplemental intake
has exact synonym: supplementation of fish oil

magnesium supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_25107
subclass of: macronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_25107
IAO_0000115: Addition of magnesium atom to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-11-30T09:00:01Z
has exact synonym: dietary supplementation of magnesium atom
has exact synonym: magnesium atom supplemental intake
has exact synonym: magnesium supplemental intake
has exact synonym: supplementation of magnesium
has exact synonym: supplementation of magnesium atom

head examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000033
subclass of: whole body examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000033
IAO_0000115: A systemic evaluation of the head using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has exact synonym: examination of head
has exact synonym: head exam
has exact synonym: physical examination of head

neck examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000974
subclass of: whole body examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000974
IAO_0000115: A systemic evaluation of the neck using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2979
date: 2021-02-10T14:39:14Z
has exact synonym: examination of neck
has exact synonym: neck exam
has exact synonym: physical examination of neck

chest examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001443
subclass of: whole body examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001443
IAO_0000115: A systemic evaluation of the chest using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-3010
date: 2021-02-10T14:39:14Z
has exact synonym: chest exam
has exact synonym: examination of chest
has exact synonym: physical examination of chest

uterus examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000995
subclass of: obstetrics and gynecology procedure
subclass of: whole body examination
subclass of: MAXO_0001407
subclass of: MAXO_0001420
subclass of: MAXO_0001443
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000995
IAO_0000115: A systemic evaluation of the uterus using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has exact synonym: examination of uterus
has exact synonym: physical examination of uterus
has exact synonym: uterus exam

cervical examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000002
subclass of: uterus examination
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000002
IAO_0000115: A systemic evaluation of the uterine cervix using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2979
date: 2021-02-10T14:39:14Z
has exact synonym: examination of the cervix
has exact synonym: examination of uterine cervix
has exact synonym: physical examination of uterine cervix
has exact synonym: uterine cervix exam

eye examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000970
subclass of: ophthalmic diagnostic procedure
subclass of: whole body examination
IAO_0000115: A systemic evaluation of the eye using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T14:39:14Z
has exact synonym: examination of eye
has exact synonym: eye exam
has exact synonym: physical examination of eye

whole body examination
type: Class
equivalent class: Class
  intersection of: physical examination
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000468
subclass of: physical examination
subclass of: diagnostic procedure by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000468
IAO_0000115: A systemic evaluation of the multicellular organism using visual inspection, palpation, and percussion. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual's health assessment.
dcterms creator: http://orcid.org/0000-0001-7941-2979
date: 2021-02-10T14:39:14Z
has exact synonym: examination of multicellular organism
has exact synonym: examination of whole body
has exact synonym: multicellular organism exam
has exact synonym: physical examination of multicellular organism
has exact synonym: whole body exam

raw fish intake avoidance
type: Class
subclass of: nutrition intake avoidance
subclass of: Restriction
  on property: avoided food
  some values from: FOODON_03308394
IAO_0000115: A medical requirement or recommendation of avoiding the consumption of fish steak (raw).
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T11:00:00Z
has exact synonym: avoid fish steak (raw) intake
has exact synonym: avoiding dietary fish steak (raw) intake
has exact synonym: fish steak (raw) consumption avoidance
has exact synonym: fish steak (raw) restricted diet intake
has exact synonym: fish steak (raw) restriction

unpasturized milk intake avoidance
type: Class
subclass of: nutrition intake avoidance
subclass of: Restriction
  on property: avoided food
  some values from: FOODON_03307455
IAO_0000115: A medical requirement or recommendation of avoiding the consumption of cow milk (raw).
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-10T11:00:00Z
has exact synonym: avoid cow milk (raw) intake
has exact synonym: avoiding dietary cow milk (raw) intake
has exact synonym: cow milk (raw) consumption avoidance
has exact synonym: cow milk (raw) restricted diet intake
has exact synonym: cow milk (raw) restriction
has exact synonym: raw milk intake avoidance
has exact synonym: unpasturised milk intake avoidance

endocervical swab collection
type: Class
equivalent class: Class
  intersection of: MAXO_0009099
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000458
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: MAXO_0009099
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000458
IAO_0000115: Collection biological material from within the endocervix with a cotton swab for use in clinical tests.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T20:39:14Z
has exact synonym: endocervical swab
has exact synonym: swab collection of endocervix

sputum specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0007311
subclass of: clinical biospecimen collection
subclass of: MAXO_0001462
IAO_0000115: Collecting of sputum for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-02-15T12:00:00Z
has exact synonym: collection of sputum specimen
has exact synonym: sputum collection

urine specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001088
subclass of: clinical biospecimen collection
subclass of: MAXO_0001452
IAO_0000115: Collecting of urine for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2974
date: 2021-02-15T12:00:00Z
has exact synonym: collection of urine specimen
has exact synonym: urine collection

semen specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001968
subclass of: clinical biospecimen collection
subclass of: MAXO_0001466
IAO_0000115: Collecting of semen for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: collection of semen specimen
has exact synonym: semen collection
has exact synonym: sperm collection

amniotic fluid specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000173
subclass of: clinical biospecimen collection
subclass of: MAXO_0001448
IAO_0000115: Collecting of amniotic fluid for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: amniotic fluid collection
has exact synonym: collection of amniotic fluid specimen

pus specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000177
subclass of: clinical biospecimen collection
subclass of: MAXO_0001457
IAO_0000115: Collecting of pus for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: collection of pus specimen
has exact synonym: pus collection

mucus specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000912
subclass of: bodily fluid specimen collection
subclass of: MAXO_0001463
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000912
IAO_0000115: Collecting of mucus for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: collection of mucus specimen
has exact synonym: mucus collection

respiratory system mucus specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0016553
subclass of: mucus specimen collection
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0016553
IAO_0000115: Collecting of respiratory system mucus for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: collection of respiratory system mucus specimen
has exact synonym: respiratory system mucus collection

nasal mucus specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002306
subclass of: respiratory system mucus specimen collection
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002306
IAO_0000115: Collecting of nasal mucus for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: collection of nasal mucus specimen
has exact synonym: nasal mucus collection

bodily fluid specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0006314
subclass of: clinical biospecimen collection
subclass of: MAXO_0001447
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0006314
IAO_0000115: Collecting of bodily fluid for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: bodily fluid collection
has exact synonym: collection of bodily fluid specimen

cerebrospinal fluid specimen collection
type: Class
equivalent class: Class
  intersection of: clinical biospecimen collection
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001359
subclass of: bodily fluid specimen collection
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001359
IAO_0000115: Collecting of cerebrospinal fluid for clinical use.
dcterms creator: http://orcid.org/0000-0001-7941-2978
date: 2021-02-15T12:00:00Z
has exact synonym: cerebral spinal fluid collection
has exact synonym: cerebrospinal fluid collection
has exact synonym: collection of cerebrospinal fluid specimen

venous ultrasonography
type: Class
equivalent class: Class
  intersection of: ultrasonography procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003920
subclass of: ultrasonography procedure
subclass of: angiography
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003920
IAO_0000115: The use of ultrasound to produce images of structures in the venous blood vessel.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-24T20:39:14Z
has exact synonym: sonography of venous blood vessel
has exact synonym: ultrasonography of venous blood vessel
has exact synonym: venous blood vessel diagnostic sonography
has exact synonym: venous blood vessel medical ultrasound
has exact synonym: venous blood vessel sonography
has exact synonym: venous blood vessel ultrasound examination
has exact synonym: venous blood vessel ultrasound imaging procedure
has exact synonym: venous blood vessel ultrasound procedure
has exact synonym: venous sonography

testicular ultrasonography
type: Class
equivalent class: Class
  intersection of: ultrasonography procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000473
subclass of: ultrasonography procedure
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000473
IAO_0000115: The use of ultrasound to produce images of structures in the testis.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-24T20:39:14Z
has exact synonym: sonography of testis
has exact synonym: testis diagnostic sonography
has exact synonym: testis medical ultrasound
has exact synonym: testis sonography
has exact synonym: testis ultrasound examination
has exact synonym: testis ultrasound imaging procedure
has exact synonym: testis ultrasound procedure
has exact synonym: ultrasonography of testis

insulin measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: PR_000050339
subclass of: protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: PR_000050339
IAO_0000115: The determination of the amount of insulin hormone present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-03-19T21:42:40Z
has exact synonym: insulin hormone assessment
has exact synonym: insulin hormone test
has exact synonym: insulin level assessment

urine albumin measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR P02768
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0001088
subclass of: albumin measurement
subclass of: urine protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR P02768
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001088
IAO_0000115: The determination of the amount of albumin (human) present in urine.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-03-19T15:25:01Z
has exact synonym: albumin (human) urine assessment
has exact synonym: urine albumin (human) test

serum protein measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR_000000001
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0001977
subclass of: protein measurement in blood
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR_000000001
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001977
IAO_0000115: The determination of the amount of protein present in blood serum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-03-19T15:25:01Z
has exact synonym: blood serum protein test
has exact synonym: protein blood serum assessment

liver transplantation
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002107
subclass of: multivisceral transplantation
subclass of: MAXO_0001413
subclass of: MAXO_0010039
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
IAO_0000115: The surgical transfer of some or all of a(n) liver from a donor to a patient.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-10-06T20:39:14Z
has db xref: NCIT:C15271
has exact synonym: liver transplantation surgical procedure
has exact synonym: transplantation of liver

potassium channel modulator agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50510
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50510
IAO_0000115: Treatment with drug or agent that regulates potassium channels.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-10T11:00:00Z
has exact synonym: K-channel modulator therapy
has exact synonym: treatment with potassium channel modulator

potassium channel blocker agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50509
subclass of: potassium channel modulator agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50509
IAO_0000115: Treatment with a drug or agent that inhibits potassium channels.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-10T11:00:00Z
has exact synonym: K-channel antagonist therapy
has exact synonym: K-channel inhibitor therapy
has exact synonym: potassium channel antagonist therapy
has exact synonym: treatment with potassium channel blocker

xanthine oxidase inhibitor agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_35634
subclass of: enzyme inhibitor agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_35634
IAO_0000115: Treatment with a drug or agent that inhibits xanthine oxidase.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-10T11:00:00Z
has exact synonym: treatment with EC 1.17.3.2 (xanthine oxidase) inhibitor

purinergic receptor P2 antagonist agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_91079
subclass of: receptor antagonist therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_91079
IAO_0000115: Treatment with a drug or agent that inhibits purinergic P2 receptor.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-10T11:00:00Z
has exact synonym: P2 antagonist therapy
has exact synonym: treatment with purinergic receptor P2 antagonist

P2Y12 receptor antagonist agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_68563
subclass of: purinergic receptor P2 antagonist agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_68563
IAO_0000115: Treatment with a drug or agent that inhibits P2Y12 receptor.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-10T11:00:00Z
has exact synonym: ADP receptor inhibitor therapy
has exact synonym: purinergic PY12 antagonist therapy
has exact synonym: treatment with P2Y12 receptor antagonist

serum alkaline phosphatase measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR_000023540
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0001977
subclass of: alkaline phosphatase measurement
subclass of: serum protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR_000023540
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001977
IAO_0000115: The determination of the amount of alkaline phosphatase present in blood serum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2021-08-12T15:25:01Z
has exact synonym: alkaline phosphatase blood serum assessment
has exact synonym: blood serum alkaline phosphatase test
has exact synonym: serum Alk phos measurement

arthroscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000982
subclass of: endoscopy by site
subclass of: MAXO_0001405
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000982
IAO_0000115: Inspection of skeletal joint using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of skeletal joint
has exact synonym: skeletal joint endoscope

bronchoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002048
subclass of: endoscopy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002048
IAO_0000115: Inspection of lung using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: airway endoscopy
has exact synonym: endoscopy of lung
has exact synonym: lung endoscope

colonoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001155
subclass of: proctoscopy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001155
IAO_0000115: Inspection of colon using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: colon endoscope
has exact synonym: endoscopy of colon

cystoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001255
subclass of: endoscopy by site
subclass of: MAXO_0001399
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001255
IAO_0000115: Inspection of urinary bladder using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of urinary bladder
has exact synonym: urinary bladder endoscope

enterosccopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002108
subclass of: endoscopy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002108
IAO_0000115: Inspection of small intestine using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of small intestine
has exact synonym: small intestine endoscope

hysteroscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000995
subclass of: endoscopy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000995
IAO_0000115: Inspection of uterus using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of uterus
has exact synonym: uterus endoscope

laparoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000916
subclass of: endoscopy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000916
IAO_0000115: Inspection of abdomen using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: abdomen endoscope
has exact synonym: endoscopy of abdomen

laryngoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001737
subclass of: endoscopy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001737
IAO_0000115: Inspection of larynx using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of larynx
has exact synonym: larynx endoscope

mediastinoscopy
type: Class
subclass of: endoscopy by site
IAO_0000115: Inspection of mediastinum using an endoscope.
date: 2022-03-16T20:39:14Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: endoscopy of mediastinum
has exact synonym: mediastinum endoscope

sigmoidoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001159
subclass of: colonoscopy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001159
IAO_0000115: Inspection of sigmoid colon using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of sigmoid colon
has exact synonym: sigmoid colon endoscope

thoracoscopy
type: Class
subclass of: endoscopy by site
IAO_0000115: Inspection of pleural cavity using an endoscope.
date: 2022-03-16T13:39:34Z
creator: http://orcid.org/0000-0001-7941-2961
has exact synonym: endoscopy of pleural cavity
has exact synonym: pleural cavity endoscope

esophagogastroduodenoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004908
subclass of: endoscopy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004908
IAO_0000115: Inspection of upper digestive tract using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: EGD
has exact synonym: OGD
has exact synonym: endoscopy of upper digestive tract
has exact synonym: oesophagogastroduodenoscopy
has exact synonym: upper GI endoscopy
has exact synonym: upper digestive tract endoscope
has exact synonym: upper endoscopy
has exact synonym: upper gastrointestinal endoscopy

ureteroscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000056
subclass of: endoscopy by site
subclass of: MAXO_0001399
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000056
IAO_0000115: Inspection of ureter using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of ureter
has exact synonym: ureter endoscope

proctoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004907
subclass of: endoscopy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004907
IAO_0000115: Inspection of lower digestive tract using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of lower digestive tract
has exact synonym: lower digestive tract endoscope

rectoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001052
subclass of: endoscopy by site
subclass of: MAXO_0001396
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001052
IAO_0000115: Inspection of rectum using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of rectum
has exact synonym: rectum endoscope

anoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001245
subclass of: endoscopy by site
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001245
IAO_0000115: Inspection of anus using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: anus endoscope
has exact synonym: endoscopy of anus

otoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001690
subclass of: endoscopy by site
subclass of: MAXO_0001445
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001690
IAO_0000115: Inspection of ear using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: ear endoscope
has exact synonym: endoscopy of ear

falloscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003889
subclass of: endoscopy by site
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003889
IAO_0000115: Inspection of fallopian tube using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of fallopian tube
has exact synonym: fallopian tube endoscope

esophagoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001043
subclass of: esophagogastroduodenoscopy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001043
IAO_0000115: Inspection of esophagus using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of esophagus
has exact synonym: esophagus endoscope
has exact synonym: oesophagoscopy

neuroendoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000955
subclass of: endoscopy by site
subclass of: MAXO_0001406
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000955
IAO_0000115: Inspection of brain using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: brain endoscope
has exact synonym: endoscopy of brain

tracheobronchoscopy
type: Class
equivalent class: Class
  intersection of: endoscopy by site
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0007196
subclass of: endoscopy by site
subclass of: MAXO_0001408
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007196
IAO_0000115: Inspection of tracheobronchial tree using an endoscope.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-16T20:39:14Z
has exact synonym: endoscopy of tracheobronchial tree
has exact synonym: tracheobronchial tree endoscope

screening for breast cancer
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100013
subclass of: cancer screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100013
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Neoplasm of the breast, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Neoplasm of the breast screening

screening for venous thrombosis
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0004936
subclass of: disease screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0004936
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Venous thrombosis, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: Venous thrombosis screening

screening for colorectal polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0200063
subclass of: screening for intestinal polyps
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0200063
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Colorectal polyposis, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Colorectal polyposis screening

screening for intestinal polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0005266
subclass of: cancer screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0005266
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Intestinal polyp, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Intestinal polyp screening

screening for uterine polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0025635
subclass of: cancer screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0025635
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Ureteral polyp, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Ureteral polyp screening

screening for cervical polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0030159
subclass of: disease screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0030159
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Cervical polyp, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Cervical polyp screening

screening for small intestinal polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0012737
subclass of: screening for intestinal polyps
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0012737
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Small intestinal polyp, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Small intestinal polyp screening

screening for gastric polyps
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0004394
subclass of: cancer screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0004394
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Multiple gastric polyps, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Multiple gastric polyps screening

screening for hepatoblastoma
type: Class
equivalent class: Class
  intersection of: disease screening
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0002884
subclass of: cancer screening
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0002884
IAO_0000115: The use of any device, marker, or other means for the purpose of detecting the presence Hepatoblastoma, usually in asymptomatic individuals.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Hepatoblastoma screening

clinical imaging procedure by system
type: Class
equivalent class: Class
  intersection of: clinical imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001062
subclass of: clinical imaging procedure
subclass of: diagnostic procedure by site
IAO_0000115: Visualization of a particular body system, organ, or cell type using a variety of imaging techniques for use in screening, diagnosis, surgical procedures or therapy.
date: 2023-02-21T18:01:42Z
creator: https://orcid.org/0000-0001-7941-2961

colorectal polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0200063
subclass of: intestinal polypectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0200063
IAO_0000115: The surgical removal (cutting out) of part or all of colorectal polyps.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Colorectal polyposis surgical removal
has exact synonym: colonic polypectomy

intestinal polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0005266
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0005266
IAO_0000115: The surgical removal (cutting out) of part or all of Intestinal polyp.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Intestinal polyp surgical removal

ureterine polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0025635
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0025635
IAO_0000115: The surgical removal (cutting out) of part or all of Ureteral polyp.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Ureteral polyp surgical removal

cervical polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0030159
subclass of: surgical excision
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0030159
IAO_0000115: The surgical removal (cutting out) of part or all of Cervical polyp.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Cervical polyp surgical removal

small intestinal polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0012737
subclass of: intestinal polypectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0012737
IAO_0000115: The surgical removal (cutting out) of part or all of Small intestinal polyp.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Small intestinal polyp surgical removal

surgical removal of Osteoma
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0100246
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0100246
IAO_0000115: The surgical removal (cutting out) of part or all of Osteoma.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Osteoma surgical removal

gastric polypectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: HP_0004394
subclass of: tumorectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: HP_0004394
IAO_0000115: The surgical removal (cutting out) of part or all of Multiple gastric polyps.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-24T20:39:14Z
has exact synonym: Multiple gastric polyps surgical removal

removal of lens
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000965
subclass of: surgical procedure on the eye
subclass of: cephalectomy
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000965
IAO_0000115: The surgical removal (cutting out) of part or all of lens of camera-type eye.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: lens of camera-type eye surgical removal

proctocolectomy
type: Class
equivalent class: Class
  intersection of: surgical excision
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0012652
subclass of: surgical excision
subclass of: MAXO_0001443
subclass of: MAXO_0001504
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0012652
IAO_0000115: The surgical removal (cutting out) of part or all of colorectum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-06-23T20:39:14Z
has exact synonym: colorectum surgical removal

serum alpha-fetoprotein measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: Class
      intersection of: PR P02771
      intersection of: Restriction
        on property: BFO_0000050
        some values from: UBERON_0001977
subclass of: serum protein measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: Class
    intersection of: PR P02771
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001977
IAO_0000115: The determination of the amount of alpha-fetoprotein present in blood serum.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-28T15:25:01Z
has exact synonym: alpha-fetoprotein (human) blood serum assessment
has exact synonym: alpha-fetoprotein serum measurement
has exact synonym: blood serum alpha-fetoprotein (human) test
has exact synonym: serum alpha-fetoprotein test

chelator agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38161
subclass of: pharmacotherapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38161
IAO_0000115: Use of a chemical compound that binds tightly to metal ions. Often used to remove toxic metals from the body.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-30T11:00:00Z
has exact synonym: treatment with chelator

copper chelator agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_166831
subclass of: chelator agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_166831
IAO_0000115: Treatrment with an agent that binds excess amounts of copper to keep it from accumulating in some parts of the body, particularly the liver.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-30T11:00:00Z
has exact synonym: treatment with copper chelator

iron chelator agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38157
subclass of: chelator agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38157
IAO_0000115: Use of a compound which binds tightly to iron molecules.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-30T11:00:00Z
has exact synonym: treatment with iron chelator

sequestrant agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_77963
subclass of: chelator agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_77963
IAO_0000115: Treatment with a sequestering agent that can envelop multiple ions at a time.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-03-30T11:00:00Z
has exact synonym: treatment with sequestrant

beta carotene measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_17579
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_17579
IAO_0000115: The determination of the amount of beta-carotene present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: b-carotene measurement
has exact synonym: beta carotene assessment
has exact synonym: beta-carotene assessment
has exact synonym: beta-carotene measurement
has exact synonym: beta-carotene test

creatine measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_16919
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_16919
IAO_0000115: The determination of the amount of creatine present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: creatine assessment
has exact synonym: creatine test

phosphocreatine measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_17287
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_17287
IAO_0000115: The determination of the amount of N-phosphocreatine present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: N-phosphocreatine assessment
has exact synonym: N-phosphocreatine test

folic acid measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27470
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27470
IAO_0000115: The determination of the amount of folic acid present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: folic acid assessment
has exact synonym: folic acid test

carnitine measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_17126
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_17126
IAO_0000115: The determination of the amount of carnitine present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: carnitine assessment
has exact synonym: carnitine test

choline measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_15354
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_15354
IAO_0000115: The determination of the amount of choline present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: choline assessment
has exact synonym: choline test

glycerylphosphorylcholine measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_135063
subclass of: phosphocholine measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_135063
IAO_0000115: The determination of the amount of glycerylphosphorylcholine present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: glycerylphosphorylcholine assessment
has exact synonym: glycerylphosphorylcholine test

phosphocholine measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_36700
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_36700
IAO_0000115: The determination of the amount of phosphocholines present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: phosphocholines assessment
has exact synonym: phosphocholines test

pyridoxal 5'-phosphate measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_18405
subclass of: chemical measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_18405
IAO_0000115: The determination of the amount of pyridoxal 5'-phosphate present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: pyridoxal 5'-phosphate assessment
has exact synonym: pyridoxal 5'-phosphate test

chemical measurement
type: Class
equivalent class: Class
  intersection of: clinical chemistry assessment
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_24431
subclass of: clinical chemistry assessment
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_24431
IAO_0000115: The determination of the amount of chemical entity present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: chemical entity assessment
has exact synonym: chemical entity test

vitamin A measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_12777
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_12777
IAO_0000115: The determination of the amount of vitamin A present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin A assessment
has exact synonym: vitamin A test

vitamin B measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_75769
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_75769
IAO_0000115: The determination of the amount of B vitamin present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: B vitamin assessment
has exact synonym: B vitamin test

vitamin B complex measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_75782
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_75782
IAO_0000115: The determination of the amount of vitamin B complex present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B complex assessment
has exact synonym: vitamin B complex test

vitamin B1 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_26948
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_26948
IAO_0000115: The determination of the amount of vitamin B1 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: thiamin measurement
has exact synonym: vitamin B1 assessment
has exact synonym: vitamin B1 test

vitamin B2 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176838
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176838
IAO_0000115: The determination of the amount of vitamin B2 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: riboflavin measurement
has exact synonym: vitamin B2 assessment
has exact synonym: vitamin B2 test

vitamin B3 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176839
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176839
IAO_0000115: The determination of the amount of vitamin B3 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: niacin measurement
has exact synonym: vitamin B3 assessment
has exact synonym: vitamin B3 test

vitamin B5 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176840
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176840
IAO_0000115: The determination of the amount of vitamin B5 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B5 assessment
has exact synonym: vitamin B5 test

vitamin B6 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27306
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27306
IAO_0000115: The determination of the amount of vitamin B6 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B6 assessment
has exact synonym: vitamin B6 test

vitamin B7 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176841
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176841
IAO_0000115: The determination of the amount of vitamin B7 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B7 assessment
has exact synonym: vitamin B7 test

vitamin B9 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176842
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176842
IAO_0000115: The determination of the amount of vitamin B9 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B9 assessment
has exact synonym: vitamin B9 test

vitamin B12 measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176843
subclass of: vitamin B measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176843
IAO_0000115: The determination of the amount of vitamin B12 present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin B12 assessment
has exact synonym: vitamin B12 test

vitamin D measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27300
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27300
IAO_0000115: The determination of the amount of vitamin D present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin D assessment
has exact synonym: vitamin D test

vitamin C measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_176783
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_176783
IAO_0000115: The determination of the amount of vitamin C present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin C assessment
has exact synonym: vitamin C test

vitamin E measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_33234
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_33234
IAO_0000115: The determination of the amount of vitamin E present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin E assessment
has exact synonym: vitamin E test

vitamin K measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_28384
subclass of: chemical measurement
subclass of: MAXO_0009069
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_28384
IAO_0000115: The determination of the amount of vitamin K present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: vitamin K assessment
has exact synonym: vitamin K test

folate measurement
type: Class
equivalent class: Class
  intersection of: MAXO_0009069
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_67011
subclass of: vitamin B9 measurement
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_67011
IAO_0000115: The determination of the amount of folates present in the sample.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-04T13:40:00Z
has exact synonym: folates assessment
has exact synonym: folates test

pelvic radiograph procedure
type: Class
equivalent class: Class
  intersection of: radiograph imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002355
subclass of: radiograph imaging procedure
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002355
IAO_0000115: Use of an imaging test that uses small amounts of radiation to produce pictures of pelvic region of trunk.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-09T20:39:14Z
has exact synonym: X-ray of the pelvis
has exact synonym: pelvic radiogram procedure
has exact synonym: pelvic region of trunk X-ray procedure
has exact synonym: pelvic region of trunk radiogram procedure
has exact synonym: pelvis radiograph
has exact synonym: radiograph of pelvic region of trunk
has exact synonym: radiograph of pelvis
has exact synonym: radiography of pelvic region of trunk

skull radiograph procedure
type: Class
equivalent class: Class
  intersection of: radiograph imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003129
subclass of: MAXO_0001405
subclass of: MAXO_0010352
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003129
IAO_0000115: Use of an imaging test that uses small amounts of radiation to produce pictures of skull.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-05-09T20:39:14Z
has exact synonym: X-ray of the skull
has exact synonym: radiograph of skull
has exact synonym: radiography of skull
has exact synonym: skull X-ray procedure
has exact synonym: skull radiogram procedure

cholic acid supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_16359
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_16359
IAO_0000115: Addition of cholic acid to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-08-25T09:00:01Z
has exact synonym: cholic acid supplemental intake
has exact synonym: dietary supplementation of cholic acid
has exact synonym: supplementation of cholic acid

vitamin K supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_28384
subclass of: fat-soluble vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_28384
IAO_0000115: Addition of vitamin K to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-08-25T09:00:01Z
has exact synonym: dietary supplementation of vitamin K
has exact synonym: supplementation of vitamin K
has exact synonym: vitamin K supplemental intake

vitamin E supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_33234
subclass of: fat-soluble vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_33234
IAO_0000115: Addition of vitamin E to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-08-25T09:00:01Z
has exact synonym: dietary supplementation of vitamin E
has exact synonym: supplementation of vitamin E
has exact synonym: vitamin E supplemental intake

vitamin A supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_12777
subclass of: fat-soluble vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_12777
IAO_0000115: Addition of vitamin A to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-09-07T09:00:01Z
has exact synonym: dietary supplementation of vitamin A
has exact synonym: supplementation of vitamin A
has exact synonym: vitamin A supplemental intake

angiography
type: Class
equivalent class: Class
  intersection of: clinical imaging procedure by system
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004537
subclass of: diagnostic procedure of cardiovascular system
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004537
IAO_0000115: A medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers.
date: 2023-02-21T18:03:45Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: arteriography

Axiom
annotated source: angiography
annotated property: IAO_0000115
annotated target: A medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers.
has db xref: Angiography

water-soluble supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_27314
subclass of: vitamin supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_27314
IAO_0000115: Addition of water-soluble vitamin (role) to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-09-07T09:00:01Z
has exact synonym: dietary supplementation of water-soluble vitamin (role)
has exact synonym: supplementation of water-soluble vitamin (role)
has exact synonym: water soluble vitamin supplementation
has exact synonym: water-soluble vitamin (role) supplemental intake

macronutrient supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_33937
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_33937
IAO_0000115: Addition of macronutrient to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-09-07T09:00:01Z
has exact synonym: dietary supplementation of macronutrient
has exact synonym: macronutrient supplemental intake
has exact synonym: supplementation of macronutrient

micronutrient supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: RO_0000087
      some values from: CHEBI_27027
subclass of: nutritional supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: RO_0000087
    some values from: CHEBI_27027
IAO_0000115: Addition of micronutrient to a diet for adequate and complete nutrition.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-09-07T09:00:01Z
has exact synonym: dietary supplementation of micronutrient
has exact synonym: micronutrient supplemental intake
has exact synonym: supplementation of micronutrient

face transplantation
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001456
subclass of: therapeutic procedure by site
subclass of: transplantation procedure
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001456
IAO_0000115: The surgical transfer of some or all of a(n) face from a donor to a patient.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-10-06T20:39:14Z
has exact synonym: transplantation of face

double lung transplant
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0000170
subclass of: MAXO_0001514
subclass of: MAXO_0010039
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0000170
IAO_0000115: The surgical transfer of a whole pair of lungs from a donor to a patient.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-10-06T10:00:01Z
has exact synonym: transplantation of whole pair of lungs

partial lung transplantation
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000101
subclass of: MAXO_0001514
subclass of: MAXO_0010039
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000101
IAO_0000115: The surgical transfer of some or all of a(n) lobe of lung from a donor to a patient.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-10-06T20:39:14Z
has exact synonym: transplantation of lobe of lung

multivisceral transplantation
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001007
subclass of: transplantation procedure
subclass of: MAXO_0001503
IAO_0000115: Transplantation of some or all of the liver, small intestine, and other abdominal organs (for example, the stomach and pancreas) at the same time.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-10-06T20:39:14Z
has exact synonym: transplantation of digestive system

selenium supplementation
type: Class
equivalent class: Class
  intersection of: nutritional supplementation
  intersection of: Restriction
    on property: RO_0002233
    some values from: CHEBI_27568
subclass of: micronutrient supplementation
subclass of: Restriction
  on property: RO_0002233
  some values from: CHEBI_27568
IAO_0000115: Addition of selenium atom to a diet for complete nutrition support.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-11-01T09:00:01Z
has db xref: PMID:27171069
has exact synonym: dietary supplementation of selenium atom
has exact synonym: selenium atom supplemental intake
has exact synonym: supplementation of selenium atom
comment: Food supplementation with selenium should be carried out in a careful and controlled way, to avoid causing the opposite effect than intended, because selenium is one of the most toxic elements in relatively small quantities being at the same time an essential micronutrient with an important biological role. The range between the necessary quantity of selenium and toxic dose is very narrow. PMID:27171069

dietary selenium atom intake avoidance
type: Class
subclass of: nutrition intake avoidance
subclass of: Restriction
  on property: avoided food
  some values from: CHEBI_27568
IAO_0000115: A medical requirement or recommendation of avoiding the consumption of selenium atom.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-11-01T09:00:01Z
has db xref: PMID:27171069
has exact synonym: avoid selenium atom intake
has exact synonym: avoiding dietary selenium atom intake
has exact synonym: selenium atom consumption avoidance
has exact synonym: selenium atom restricted diet intake
has exact synonym: selenium atom restriction
comment: Food supplementation with selenium should be carried out in a careful and controlled way, to avoid causing the opposite effect than intended, because selenium is one of the most toxic elements in relatively small quantities being at the same time an essential micronutrient with an important biological role. The range between the necessary quantity of selenium and toxic dose is very narrow. PMID:27171069

clinical biopsy
type: Class
subclass of: clinical biospecimen collection
IAO_0000115: A specimen collection from a patient that is used for diagnostic purposes.
date: 2022-12-08T20:39:14Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: OBI:0002650
has exact synonym: diagnostic biopsy

clinical computed tomography assisted biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002652
subclass of: clinical image guided biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002652
IAO_0000115: Use of computed tomography assisted biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002652
comment: A needle biopsy guided by real-time computed tomography (CT) scan images. OBI:0002652

clinical core needle biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002656
subclass of: clinical needle biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002656
IAO_0000115: Use of core needle biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002656
comment: A biopsy that uses a hollow tube to collect a core of tissue. OBI:0002656

clinical fine needle aspiration biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002655
subclass of: clinical needle biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002655
IAO_0000115: Use of fine needle aspiration biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002655
comment: A biopsy that uses a thin needle to extract cells. OBI:0002655

clinical image guided biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002651
subclass of: clinical needle biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002651
IAO_0000115: Use of image guided biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002651
comment: A biopsy which uses an imaging procedure to guide a needle biopsy. OBI:0002651

clinical needle biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002654
subclass of: clinical biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002654
IAO_0000115: Use of needle biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002654
comment: A biopsy that uses a hollow needle to extract cells. OBI:0002654

clinical surgical biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002657
subclass of: clinical biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002657
IAO_0000115: Use of surgical biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002657
comment: A biopsy involving a surgical incision into an organism to access the biopsy material. OBI:0002657

clinical ultrasound-guided needle biopsy
type: Class
equivalent class: Class
  intersection of: clinical biopsy
  intersection of: Restriction
    on property: BFO_0000051
    some values from: OBI_0002653
subclass of: clinical image guided biopsy
subclass of: Restriction
  on property: BFO_0000051
  some values from: OBI_0002653
IAO_0000115: Use of ultrasound-guided needle biopsy to removal and examination of tissue, cells, or fluids from a patient purpose of detecting or characterizing disease.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-12-08T20:39:14Z
has db xref: OBI:0002653
comment: An ultrasound-guided needle biopsy uses sound waves to help locate a nodule or abnormality within the thyroid. OBI:0002653

surgical repair of coronary artery
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001621
subclass of: surgical repair of artery
subclass of: MAXO_0025002
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001621
IAO_0000115: A surgery that fixes or mends coronary artery.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: coronary artery surgical repair

heart valve repair
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000946
subclass of: MAXO_0025002
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000946
IAO_0000115: A surgery that fixes or mends cardiac valve.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: cardiac valve surgical repair

surgical repair of tricuspid valve
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002134
subclass of: heart valve repair
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002134
IAO_0000115: A surgery that fixes or mends tricuspid valve.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: tricuspid valve surgical repair

surgical repair of pulmonary valve
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002146
subclass of: heart valve repair
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002146
IAO_0000115: A surgery that fixes or mends pulmonary valve.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: pulmonary valve surgical repair

surgical repair of aorta
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000947
subclass of: surgical repair of cardiovascular system
subclass of: MAXO_0001515
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000947
IAO_0000115: A surgery that fixes or mends aorta.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: aorta surgical repair

surgical repair of endocrine gland
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002368
subclass of: surgery by body site
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002368
IAO_0000115: A surgery that fixes or mends endocrine gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: endocrine gland surgical repair

surgical repair of fallopian tube
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003889
subclass of: MAXO_0001443
subclass of: MAXO_0001512
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003889
IAO_0000115: A surgery that fixes or mends fallopian tube.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: fallopian tube surgical repair

surgical repair of pancreas
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001264
subclass of: surgery by body site
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
IAO_0000115: A surgery that fixes or mends pancreas.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: pancreas surgical repair

surgical repair of eye
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000970
subclass of: surgery by body site
subclass of: MAXO_0001397
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000970
IAO_0000115: A surgery that fixes or mends eye.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: eye surgical repair

surgical repair of digestive tract
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001555
subclass of: MAXO_0001503
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001555
IAO_0000115: A surgery that fixes or mends digestive tract.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: digestive tract surgical repair

surgical repair of ligament
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000211
subclass of: surgery by body site
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000211
IAO_0000115: A surgery that fixes or mends ligament.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: ligament surgical repair

surgical repair of vertebra
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002412
subclass of: orthopedic surgery
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002412
IAO_0000115: A surgery that fixes or mends vertebra.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: vertebra surgical repair

surgical repair of bone tissue
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002481
subclass of: orthopedic surgery
subclass of: MAXO_0001443
subclass of: MAXO_0009072
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002481
IAO_0000115: A surgery that fixes or mends bone tissue.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: bone tissue surgical repair

surgical plastic reconstruction of ear
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001690
subclass of: surgery by body site
subclass of: MAXO_0001422
subclass of: MAXO_0001443
subclass of: MAXO_0009076
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001690
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of ear. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: ear surgical plastic reconstruction

cranioplasty
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0003128
subclass of: orthopedic surgery
subclass of: MAXO_0009076
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003128
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of cranium. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: cranium surgical plastic reconstruction

surgical plastic reconstruction of face
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001456
subclass of: therapeutic procedure by site
subclass of: MAXO_0009076
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001456
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of face. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: face surgical plastic reconstruction

hand reconstructive plastic surgery
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002398
subclass of: therapeutic procedure by site
subclass of: MAXO_0009076
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002398
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of manus. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: manus surgical plastic reconstruction
has exact synonym: reconstructive plastic surgery of hand

septoplasty
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001706
subclass of: cranioplasty
subclass of: surgical plastic reconstruction of face
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001706
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of nasal septum. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: nasal septum surgical plastic reconstruction

bronchoplasty
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002185
subclass of: MAXO_0001443
subclass of: MAXO_0001514
subclass of: MAXO_0009076
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002185
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of bronchus. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: bronchus surgical plastic reconstruction

iridoplasty
type: Class
equivalent class: Class
  intersection of: MAXO_0009076
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001769
subclass of: surgical procedure on the eye
subclass of: surgical repair of eye
subclass of: surgical plastic reconstruction of face
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001769
IAO_0000115: A medically necessary surgery performed to restore function and conventional appearance of iris. The surgery can correct deformities created by birth defects, trauma or medical conditions and is performed by a plastic surgeon.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-14T20:39:14Z
has exact synonym: gonioplasty
has exact synonym: iris surgical plastic reconstruction
comment: iridoplasty can be performed despite corneal clouding, whereas iridotomy cannot

surgical repair of cardiovascular system
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0004535
subclass of: MAXO_0009072
subclass of: MAXO_0025001
IAO_0000115: A surgery that fixes or mends cardiovascular system.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: cardiovascular system surgical repair

therapy
type: Class
subclass of: therapeutic procedure
IAO_0000115: A treatment that helps someone feel better, grow stronger, etc., especially after an illness.
date: 2023-04-13T17:54:15Z
creator: https://orcid.org/0000-0001-7941-2961

surgical repair of pericardium
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002407
subclass of: surgical repair of cardiovascular system
subclass of: MAXO_0001443
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002407
IAO_0000115: A surgery that fixes or mends pericardium.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: pericardium surgical repair

surgical repair of artery
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001637
subclass of: surgical repair of cardiovascular system
subclass of: MAXO_0001515
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001637
IAO_0000115: A surgery that fixes or mends artery.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: artery surgical repair

surgical repair of vein
type: Class
equivalent class: Class
  intersection of: MAXO_0009072
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001638
subclass of: surgical repair of cardiovascular system
subclass of: MAXO_0001515
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001638
IAO_0000115: A surgery that fixes or mends vein.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2022-07-25T20:39:14Z
has exact synonym: vein surgical repair

MRI of the placenta
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001987
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001407
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001987
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the placenta.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the placenta
has exact synonym: placenta MRI
has exact synonym: placenta magnetic resonance imaging

cardiac MRI
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0000948
subclass of: magnetic resonance imaging procedure
subclass of: diagnostic procedure of cardiovascular system
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000948
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the heart.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the heart
has exact synonym: heart MRI
has exact synonym: heart magnetic resonance imaging

MRI of the vertebral column
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001130
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001405
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001130
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the vertebral column.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: MRI of the spinal column
has exact synonym: Nuclear magnetic resonance imaging of the vertebral column
has exact synonym: spinal column MRI
has exact synonym: vertebral column MRI
has exact synonym: vertebral column magnetic resonance imaging

MRI of the kidney
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002113
subclass of: MRI of the abdomen
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the kidney.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the kidney
has exact synonym: kidney MRI
has exact synonym: kidney magnetic resonance imaging

MRI of the liver
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002107
subclass of: MRI of the abdomen
subclass of: MAXO_0001396
subclass of: MAXO_0001400
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the liver.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the liver
has exact synonym: liver MRI
has exact synonym: liver magnetic resonance imaging

total body MRI
type: Class
subclass of: magnetic resonance imaging procedure
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the whole body.
date: 2023-02-10T20:39:14Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: MRI of whole body
has exact synonym: total body magnetic resonance imaging

cervical spine MRI
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0006072
subclass of: MRI of the vertebral column
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0006072
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the cervical region of vertebral column.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: MRI of cervical spine
has exact synonym: Nuclear magnetic resonance imaging of the cervical region of vertebral column
has exact synonym: cervical region of vertebral column MRI
has exact synonym: cervical region of vertebral column magnetic resonance imaging

MRI of the adrenal gland
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002369
subclass of: MRI of the abdomen
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002369
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the adrenal gland.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the adrenal gland
has exact synonym: adrenal gland MRI
has exact synonym: adrenal gland magnetic resonance imaging

MRI of the pancreas
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001264
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the pancreas.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the pancreas
has exact synonym: pancreas MRI
has exact synonym: pancreas magnetic resonance imaging

MRI of the limb
type: Class
equivalent class: Class
  intersection of: magnetic resonance imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0002101
subclass of: magnetic resonance imaging procedure
subclass of: clinical imaging procedure by system
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002101
IAO_0000115: A medical examination performed using of magnetic resonance imaging to image the limb.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: Nuclear magnetic resonance imaging of the limb
has exact synonym: limb MRI
has exact synonym: limb magnetic resonance imaging

whole organ transplantation
type: Class
equivalent class: Class
  intersection of: transplantation procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0000062
subclass of: surgery by body site
subclass of: transplantation procedure
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0000062
IAO_0000115: The transfer of a whole organ from one body to another.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2020-01-20T10:00:01Z
has db xref: NCIT:C122934
has exact synonym: transplantation of whole organ

X-ray pulmonary angiography procedure
type: Class
equivalent class: Class
  intersection of: radiograph imaging with contrast dye
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37334
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0008886
subclass of: radiograph imaging with contrast dye
subclass of: angiography
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0008886
IAO_0000115: An X-ray imaging technique that involves visualization of the pulmonary vasculature after fluoroscopy-guided catheter placement and injection of an iodinated contrast medium into the pulmonary circulation.
date: 2023-02-21T18:31:55Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C154789
has exact synonym: X-ray of pulmonary vasculature
has exact synonym: contrast pulmonary angiography

Axiom
annotated source: X-ray pulmonary angiography procedure
annotated property: IAO_0000115
annotated target: An X-ray imaging technique that involves visualization of the pulmonary vasculature after fluoroscopy-guided catheter placement and injection of an iodinated contrast medium into the pulmonary circulation.
has db xref: NCIT:C154789

X-ray cerebral angiography procedure
type: Class
equivalent class: Class
  intersection of: radiograph imaging with contrast dye
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37334
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0003499
subclass of: MAXO_0001406
subclass of: MAXO_0001467
subclass of: MAXO_0035038
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0003499
IAO_0000115: The X-ray examination of the blood vessels in and around the brain.
date: 2023-02-21T18:40:16Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: X-ray of brain blood vessels
has exact synonym: contrast cerebral angiography

dental radiography
type: Class
equivalent class: Class
  intersection of: radiograph imaging procedure
  intersection of: Restriction
    on property: RO_0002233
    some values from: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001091
subclass of: radiograph imaging procedure
subclass of: clinical imaging procedure by system
subclass of: MAXO_0001405
subclass of: MAXO_0001467
subclass of: Restriction
  on property: RO_0002233
  some values from: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001091
IAO_0000115: Use of an imaging test that uses small amounts of radiation to produce pictures of teeth.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-10T20:39:14Z
has exact synonym: calcareous tooth X-ray procedure
has exact synonym: calcareous tooth radiogram procedure
has exact synonym: radiograph of calcareous tooth
has exact synonym: radiography of calcareous tooth

microangiography
type: Class
subclass of: angiography
IAO_0000115: Imaging of small blood or lymphatic vessels less than 200 micrometers in diameter.
date: 2023-02-21T18:58:06Z
creator: https://orcid.org/0000-0001-7941-2961

X-ray microangiography
type: Class
subclass of: radiograph imaging with contrast dye
subclass of: microangiography
IAO_0000115: Radiography of small blood or lymphatic vessels of an organ less than 200 micrometers in diameter.
date: 2023-02-21T18:59:46Z
creator: https://orcid.org/0000-0001-7941-2961

fluorescent microangiography
type: Class
subclass of: microangiography
IAO_0000115: This test consists of injecting indocyanine green dye (ICG) through a peripheral intravenous line. The ICG subsequently binds to blood lipoproteins and travels to where there is blood flow. Using a near-infrared laser coupled with a camera, one can then visualize blood flow within 3–5 millimeters of the skin surface.
date: 2023-02-21T19:02:21Z
creator: https://orcid.org/0000-0001-7941-2961
comment: This technique can be used as a bedside diagnosis for frostbite

Axiom
annotated source: fluorescent microangiography
annotated property: IAO_0000115
annotated target: This test consists of injecting indocyanine green dye (ICG) through a peripheral intravenous line. The ICG subsequently binds to blood lipoproteins and travels to where there is blood flow. Using a near-infrared laser coupled with a camera, one can then visualize blood flow within 3–5 millimeters of the skin surface.
has db xref: PMID:36409932

X-ray coronary angiography procedure
type: Class
equivalent class: Class
  intersection of: radiograph imaging with contrast dye
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_37334
  intersection of: Restriction
    on property: RO_0002233
    some values from: UBERON_0013768
subclass of: MAXO_0035038
subclass of: Restriction
  on property: RO_0002233
  some values from: UBERON_0013768
IAO_0000115: The X-ray examination of the blood vessels of the heart.
date: 2023-02-21T19:09:18Z
creator: https://orcid.org/0000-0001-7941-2961
has exact synonym: X-ray of the blood vessel in the heart
has exact synonym: contrast coronary angiography

GABA antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_65259
subclass of: receptor antagonist therapy
subclass of: GABA augmenting agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_65259
IAO_0000115: Use of a drug or agent that inhibits GABA signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with GABA antagonist

nuclear medicine imaging procedure
type: Class
subclass of: clinical imaging procedure
IAO_0000115: Use of a small amount of radioactive chemical called a tracer that can aid in imaging a target organ. The tracer emits gamma rays which are detected by a gamma radiation camera and analyzed by a computer to form the image of the desired region.
date: 2023-02-21T19:50:18Z
creator: https://orcid.org/0000-0001-7941-2961
has db xref: NCIT:C62667
has exact synonym: nuclear medicine scan
has exact synonym: radioimaging
has exact synonym: radionuclide imaging
has exact synonym: radionuclide scanning
has exact synonym: scintigraphy

GABA modulator therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_50268
subclass of: GABA augmenting agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_50268
IAO_0000115: Use of a drug or agent that does not act as agonist or antagonist but does affect GABA-ionophore complex signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with GABA modulator

cholinergic agent therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38323
subclass of: MAXO_0001336
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38323
IAO_0000115: Treatment with a drug or agent that modifies cholinergic signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with cholinergic drug

cholinergic agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38324
subclass of: cholinergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38324
IAO_0000115: Treatment with drug or agent that activates cholinergic signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with cholinergic agonist

muscarinic agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_38325
subclass of: cholinergic agonist therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_38325
IAO_0000115: Treatment with drug or agent to activate muscarinic signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with muscarinic agonist

nicotinic acetylcholine receptor agonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_47958
subclass of: cholinergic agonist therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_47958
IAO_0000115: Use of a drug or agent that activates nicotinic acetylcholine receptor signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with nicotinic acetylcholine receptor agonist

cholinergic antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48873
subclass of: cholinergic agent therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48873
IAO_0000115: Treatment with a drug or agent that inhibits cholinergic signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: anticholinergic agent therapy
has exact synonym: treatment with cholinergic antagonist

muscarinic antagonist therapy
type: Class
equivalent class: Class
  intersection of: pharmacotherapy
  intersection of: Restriction
    on property: therapeutic uses
    some values from: Class
      intersection of: CHEBI_24431
      intersection of: Restriction
        on property: RO_0000087
        some values from: CHEBI_48876
subclass of: cholinergic antagonist therapy
subclass of: Restriction
  on property: therapeutic uses
  some values from: Class
    intersection of: CHEBI_24431
    intersection of: Restriction
      on property: RO_0000087
      some values from: CHEBI_48876
IAO_0000115: Treatment with a drug or agent to inhibit muscarinic signaling.
dcterms creator: http://orcid.org/0000-0001-7941-2961
date: 2023-02-23T11:00:00Z
has exact synonym: treatment with muscarinic antagonist