part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
IAO_0000115: For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)
IAO_0000115: a core relation that holds between a part and its whole
label: part_of

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
IAO_0000115: Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2.
IAO_0000115: a core relation that holds between a whole and its part
label: has_part

realized in
type: ObjectProperty
inverse of: realizes
domain: realizable entity
range: process

realizes
type: ObjectProperty
domain: process
range: realizable entity

preceded_by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000115: X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)
IAO_0000115: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
has exact synonym: is preceded by
has exact synonym: takes place after
label: preceded by

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000115: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.

occurs in
type: ObjectProperty
inverse of: contains process
domain: occurrent
range: independent continuant
property chain axiom: part of
IAO_0000115: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t

contains process
type: ObjectProperty
IAO_0000115: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t

is about
type: ObjectProperty
domain: information content entity
IAO_0000115: A (currently) primitive relation that relates an information artifact to an entity.
IAO_0000115: is_about is a (currently) primitive relation that relates an information artifact to an entity.

has_specified_input
type: ObjectProperty
equivalent property:
  inverse of: is_specified_input_of
sub property of: has participant
inverse of: is_specified_input_of
domain: planned process
IAO_0000115: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.

is_specified_input_of
type: ObjectProperty
sub property of: participates_in
range: planned process
IAO_0000115: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.

has_specified_output
type: ObjectProperty
equivalent property:
  inverse of: is_specified_output_of
sub property of: has participant
inverse of: is_specified_output_of
domain: planned process
IAO_0000115: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.

is_specified_output_of
type: ObjectProperty
equivalent property:
  inverse of: has_specified_output
sub property of: participates_in
range: planned process
IAO_0000115: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.

achieves_planned_objective
type: ObjectProperty
inverse of: objective_achieved_by
domain: planned process
range: objective specification
IAO_0000115: This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.

objective_achieved_by
type: ObjectProperty
domain: objective specification
range: planned process
IAO_0000115: This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
IAO_0000115: This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.

inheres in
type: ObjectProperty
sub property of: inheres in part of
inverse of: bearer of
IAO_0000115: a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence

bearer of
type: ObjectProperty
range: specifically dependent continuant
IAO_0000115: a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence

participates_in
type: ObjectProperty
inverse of: has participant
domain: continuant
range: occurrent
IAO_0000115: a relation between a continuant and a process, in which the continuant is somehow involved in the process
label: participates in

has participant
type: ObjectProperty
domain: occurrent
range: continuant
property chain axiom: has part
IAO_0000115: a relation between a process and a continuant, in which the continuant is somehow involved in the process

is concretized as
type: ObjectProperty
inverse of: concretizes
domain: generically dependent continuant
range: specifically dependent continuant
IAO_0000115: A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants.

concretizes
type: ObjectProperty
domain: specifically dependent continuant
range: generically dependent continuant
IAO_0000115: A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.

role of
type: ObjectProperty
sub property of: inheres in
inverse of: has role
IAO_0000115: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence

has role
type: ObjectProperty
sub property of: bearer of
sub property of: depends on
domain: independent continuant
range: role
IAO_0000115: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
label: has_role

derives from
type: ObjectProperty
sub property of: topObjectProperty
inverse of: derives into
domain: independent continuant
range: independent continuant
IAO_0000115: a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity

derives into
type: ObjectProperty
IAO_0000115: a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity

has regulatory component activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulated by
IAO_0000115: A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.

has negative regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: negatively regulated by
IAO_0000115: A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.

has positive regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: positively regulated by
IAO_0000115: A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.

has component activity
type: ObjectProperty
sub property of: has component process

has component process
type: ObjectProperty
sub property of: has component
domain: process
range: process
IAO_0000115: w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.

directly regulated by
type: ObjectProperty
sub property of: regulated by
inverse of: directly regulates

directly negatively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly negatively regulates
IAO_0000115: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.

directly positively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly positively regulates
IAO_0000115: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.

has effector activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulates
type: FunctionalProperty
IAO_0000115: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty

immediately_preceded_by
type: ObjectProperty
sub property of: preceded_by
inverse of: immediately precedes
IAO_0000115: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)
has exact synonym: directly preceded by
has exact synonym: is directly preceded by
has exact synonym: is immediately preceded by
has exact synonym: starts_at_end_of
label: immediately preceded by

immediately precedes
type: ObjectProperty
sub property of: precedes

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
property chain axiom: part of
property chain axiom: has part
IAO_0000115: x overlaps y if and only if there exists some z such that x has part z and z part of y

has component
type: ObjectProperty
sub property of: has part
IAO_0000115: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
label: has_component

regulates
type: ObjectProperty
sub property of: causally upstream of
inverse of: regulated by
type: TransitiveProperty
domain: process
range: process
property chain axiom: has effector activity
property chain axiom: directly regulates
IAO_0000115: process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.
label: regulates (processual)

negatively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, negative effect
inverse of: negatively regulated by
IAO_0000115: Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.

positively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, positive effect
inverse of: positively regulated by
type: TransitiveProperty
property chain axiom: negatively regulates
IAO_0000115: Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.

capable of
type: ObjectProperty
sub property of: capable of part of
sub property of: functionally related to
domain: independent continuant
range: process
IAO_0000115: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
label: capable_of

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
IAO_0000115: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.

temporally related to
type: ObjectProperty
domain: occurrent
range: occurrent

starts
type: ObjectProperty
sub property of: part of
inverse of: starts with
IAO_0000115: Relation between occurrents, shares a start boundary with.

starts with
type: ObjectProperty
sub property of: has part
type: TransitiveProperty

ends
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
IAO_0000115: Relation between occurrents, shares an end boundary with.
IAO_0000115: inverse of ends with
has exact synonym: finishes

ends with
type: ObjectProperty
sub property of: has part
type: TransitiveProperty

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: process
range: material entity
IAO_0000115: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.

has output
type: ObjectProperty
sub property of: has participant
IAO_0000115: p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p.

related via exposure to
type: ObjectProperty
sub property of: causally related to
domain: exposure event or process
IAO_0000115: Any relationship between an exposure event or process and any other entity.

acts upstream of
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of
IAO_0000115: c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.

acts upstream of or within
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: enables
property chain axiom: causally upstream of or within
IAO_0000115: c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
has related synonym: affects

causally upstream of, positive effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, positive effect

causally upstream of, negative effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, negative effect

has exposure stimulus
type: ObjectProperty
sub property of: related via exposure to
IAO_0000115: A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.

inheres in part of
type: ObjectProperty
sub property of: depends on
property chain axiom: inheres in
property chain axiom: part of
IAO_0000115: q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.

mereotopologically related to
type: ObjectProperty
IAO_0000115: A mereological relationship or a topological relationship

enables
type: ObjectProperty
sub property of: capable of
inverse of: enabled by
property chain axiom: has part
property chain axiom: has component activity

functionally related to
type: ObjectProperty
IAO_0000115: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
IAO_0000115: this relation holds between c and p when c is part of some c', and c' is capable of p.

involved in
type: ObjectProperty
sub property of: participates_in
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: part of
IAO_0000115: c involved_in p if and only if c enables some process p', and p' is part of p

enabled by
type: ObjectProperty
sub property of: has participant
sub property of: functionally related to
IAO_0000115: inverse of enables

regulated by
type: ObjectProperty
sub property of: causally downstream of or within
type: TransitiveProperty
domain: process
range: process
IAO_0000115: inverse of regulates

negatively regulated by
type: ObjectProperty
sub property of: regulated by
IAO_0000115: inverse of negatively regulates

positively regulated by
type: ObjectProperty
sub property of: regulated by
IAO_0000115: inverse of positively regulates

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
IAO_0000115: is member of is a mereological relation between a item and a collection.

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
IAO_0000115: has member is a mereological relation between a collection and an item.

input of
type: ObjectProperty
sub property of: participates_in
sub property of: functionally related to
IAO_0000115: inverse of has input

output of
type: ObjectProperty
sub property of: participates_in
sub property of: functionally related to
IAO_0000115: inverse of has output

causally downstream of
type: ObjectProperty
sub property of: preceded_by
sub property of: causally downstream of or within
inverse of: causally upstream of
IAO_0000115: inverse of upstream of

immediately causally downstream of
type: ObjectProperty
sub property of: immediately_preceded_by
sub property of: causally downstream of
inverse of: immediately causally upstream of

causally related to
type: ObjectProperty
IAO_0000115: This relation groups causal relations between material entities and causal relations between processes

causally upstream of
type: ObjectProperty
sub property of: precedes
sub property of: causally upstream of or within
type: TransitiveProperty
IAO_0000115: p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain

immediately causally upstream of
type: ObjectProperty
sub property of: immediately precedes
sub property of: causally upstream of
IAO_0000115: p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
IAO_0000115: p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.
has related synonym: affects

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
IAO_0000115: inverse of causally upstream of or within

involved in regulation of
type: ObjectProperty
sub property of: acts upstream of
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: regulates
property chain axiom: involved in
IAO_0000115: c involved in regulation of p if c is involved in some p' and p' regulates some p

involved in positive regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: positively regulates
property chain axiom: involved in
IAO_0000115: c involved in regulation of p if c is involved in some p' and p' positively regulates some p

involved in negative regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: negatively regulates
property chain axiom: involved in
IAO_0000115: c involved in regulation of p if c is involved in some p' and p' negatively regulates some p

involved in or involved in regulation of
type: ObjectProperty
sub property of: acts upstream of or within
sub property of: functionally related to
sub property of: causal agent in process
IAO_0000115: c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p

is active in
type: ObjectProperty
sub property of: overlaps
sub property of: functionally related to
property chain axiom: enables
property chain axiom: occurs in
IAO_0000115: c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
has exact synonym: enables activity in

interacts with
type: ObjectProperty
type: SymmetricProperty
domain: material entity
range: material entity
IAO_0000115: A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
has exact synonym: in pairwise interaction with

molecularly interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
IAO_0000115: An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.

phosphorylates
type: ObjectProperty
sub property of: molecularly interacts with

directly regulates activity of
type: ObjectProperty
sub property of: molecularly interacts with
sub property of: regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: regulates
property chain axiom: enabled by
IAO_0000115: The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
has exact synonym: molecularly controls

directly negatively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly negatively regulates
property chain axiom: enabled by
IAO_0000115: The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
has exact synonym: molecularly decreases activity of

directly positively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly positively regulates
property chain axiom: enabled by
IAO_0000115: The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
has exact synonym: molecularly increases activity of

helper property (not for use in curation)
type: ObjectProperty

has part that occurs in
type: ObjectProperty
domain: occurrent
range: independent continuant
property chain axiom: has part
property chain axiom: occurs in
IAO_0000115: p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.

is kinase activity
type: ObjectProperty
sub property of: molecular interaction relation helper property

relation between physical entity and a process or stage
type: ObjectProperty
domain: independent continuant
domain: Class
  union of: material anatomical entity
  union of: immaterial anatomical entity
range: occurrent

existence starts during or after
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: preceded_by
IAO_0000115: x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).

existence ends during or before
type: ObjectProperty
property chain axiom: part of
property chain axiom: precedes

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
IAO_0000115: A relationship between a material entity and a process where the material entity has some causal role that influences the process

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: occurrent
range: occurrent
IAO_0000115: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.

depends on
type: ObjectProperty

causal relation between entities
type: ObjectProperty
sub property of: causally related to
domain: continuant
range: continuant

causally influenced by
type: ObjectProperty
sub property of: causal relation between entities
inverse of: causally influences

interaction relation helper property
type: ObjectProperty
sub property of: helper property (not for use in curation)

molecular interaction relation helper property
type: ObjectProperty
sub property of: interaction relation helper property

causally influences
type: ObjectProperty
sub property of: causal relation between entities
domain: continuant
range: continuant
property chain axiom: enables
property chain axiom: causally upstream of
property chain axiom: has input
property chain axiom: enabled by
IAO_0000115: The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).

has modifier
type: ObjectProperty
domain: specifically dependent continuant
range: specifically dependent continuant
IAO_0000115: A relation that holds between an attribute or a qualifier and another attribute.

directly regulates
type: ObjectProperty
sub property of: regulates
sub property of: immediately causally upstream of
IAO_0000115: Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
IAO_0000115: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: material entity
range: process
IAO_0000115: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.

capable of regulating
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: regulates
IAO_0000115: Holds between c and p if and only if c is capable of some activity a, and a regulates p.

capable of negatively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: negatively regulates
IAO_0000115: Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.

capable of positively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: positively regulates
IAO_0000115: Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.

process has causal agent
type: ObjectProperty
sub property of: causally related to
IAO_0000115: Inverse of 'causal agent in process'

directly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: directly regulates
IAO_0000115: Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.

directly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: directly regulates
IAO_0000115: Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.

enables subfunction
type: ObjectProperty
sub property of: functionally related to
property chain axiom: enables
property chain axiom: has part
IAO_0000115: Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.

acts upstream of or within, positive effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, positive effect

acts upstream of or within, negative effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, negative effect

acts upstream of, positive effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, positive effect
property chain axiom: enables
property chain axiom: causally upstream of, positive effect
IAO_0000115: c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive

acts upstream of, negative effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, negative effect
property chain axiom: enables
property chain axiom: causally upstream of, negative effect
IAO_0000115: c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative

causally upstream of or within, negative effect
type: ObjectProperty
sub property of: causally upstream of or within

causally upstream of or within, positive effect
type: ObjectProperty
sub property of: causally upstream of or within

regulates activity of
type: ObjectProperty
sub property of: causally influences
domain: material entity
range: material entity
IAO_0000115: The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.

has functional parent
type: ObjectProperty

has parent hydride
type: ObjectProperty

is conjugate acid of
type: ObjectProperty
inverse of: is conjugate base of

is conjugate base of
type: ObjectProperty

is substituent group from
type: ObjectProperty

interacts_with
type: ObjectProperty

interacts_with_an_exposure_receptor_via
type: ObjectProperty

interacts_with_an_exposure stressor_via
type: ObjectProperty

decreased_in_magnitude_relative_to
type: ObjectProperty
sub property of: different_in_magnitude_relative_to
type: TransitiveProperty
domain: quality
range: quality
IAO_0000115: q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.

different_in_magnitude_relative_to
type: ObjectProperty
domain: quality
range: quality
IAO_0000115: q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.

increased_in_magnitude_relative_to
type: ObjectProperty
sub property of: different_in_magnitude_relative_to
type: TransitiveProperty
domain: quality
range: quality
IAO_0000115: q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.

reciprocal_of
type: ObjectProperty
IAO_0000115: q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.

entity
type: Class

continuant
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: continuant
IAO_0000115: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.

occurrent
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: occurrent
IAO_0000115: An entity that has temporal parts and that happens, unfolds or develops through time.

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: independent continuant
IAO_0000115: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
IAO_0000115: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])

process
type: Class
subclass of: occurrent
IAO_0000115: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
IAO_0000115: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])

realizable entity
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of
  all values from: realizable entity
IAO_0000115: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.

quality
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of
  all values from: quality

specifically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: specifically dependent continuant
IAO_0000115: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
IAO_0000115: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
IAO_0000115: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])

role
type: Class
subclass of: realizable entity
IAO_0000115: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.

fiat object
type: Class
subclass of: material entity
label: fiat object part

object
type: Class
subclass of: material entity

generically dependent continuant
type: Class
subclass of: continuant
IAO_0000115: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
IAO_0000115: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])

material entity
type: Class
subclass of: independent continuant
IAO_0000115: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.

immaterial entity
type: Class
subclass of: independent continuant

anatomical entity
type: Class
subclass of: biological entity

material anatomical entity
type: Class
subclass of: material entity
subclass of: anatomical entity

immaterial anatomical entity
type: Class
subclass of: immaterial entity

biological entity
type: Class
subclass of: independent continuant

electron
type: Class
subclass of: lepton
IAO_0000115: Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
has exact synonym: electron
has related synonym: Elektron
has related synonym: beta
has related synonym: beta(-)
has related synonym: beta-particle
has related synonym: e
has related synonym: e(-)
has related synonym: e-
has related synonym: negatron

endocrine disruptor
type: Class
subclass of: hormone receptor modulator
IAO_0000115: Any compound that can disrupt the functions of the endocrine (hormone) system
has related synonym: endocrine disrupting chemical
has related synonym: endocrine disrupting chemicals
has related synonym: endocrine disrupting compound
has related synonym: endocrine disrupting compounds
has related synonym: endocrine disruptors
has related synonym: endocrine-disrupting chemical
has related synonym: endocrine-disrupting chemicals
has related synonym: hormonally active agent
has related synonym: hormonally active agents

inorganic acid
type: Class
subclass of: Bronsted acid
IAO_0000115: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
has related synonym: inorganic acids
has related synonym: mineral acid
has related synonym: mineral acids

gas molecular entity
type: Class
subclass of: main group molecular entity
IAO_0000115: Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
has related synonym: gas molecular entities
has related synonym: gaseous molecular entities
has related synonym: gaseous molecular entity

alpha-hydroxy ketone
type: Class
subclass of: alcohol
subclass of: alpha-oxyketone
IAO_0000115: An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety.
has related synonym: alpha-hydroxy ketones
has related synonym: alpha-hydroxy-ketone
has related synonym: alpha-hydroxy-ketones
has related synonym: alpha-hydroxyketone
has related synonym: alpha-hydroxyketones

tertiary alpha-hydroxy ketone
type: Class
subclass of: alpha-hydroxy ketone
subclass of: tertiary alcohol
IAO_0000115: An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups.
has related synonym: tertiary alpha-hydroxy ketones
has related synonym: tertiary alpha-hydroxy-ketone
has related synonym: tertiary alpha-hydroxy-ketones
has related synonym: tertiary alpha-hydroxyketone
has related synonym: tertiary alpha-hydroxyketones

a tetracycline zwittterion
type: Class
subclass of: tetracyclines
has related synonym: a tetracycline

emetic
type: Class
subclass of: drug
IAO_0000115: Any agent that induces nausea and vomiting.
has related synonym: emetics

electron donor
type: Class
subclass of: donor
IAO_0000115: A molecular entity that can transfer an electron to another molecular entity.
has exact synonym: electron donor
has related synonym: Elektronendonator
has related synonym: donneur d'electron

acceptor
type: Class
subclass of: chemical role
IAO_0000115: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
has exact synonym: Acceptor
has related synonym: A
has related synonym: Akzeptor
has related synonym: Hydrogen-acceptor
has related synonym: Oxidized donor
has related synonym: accepteur

acetic acid
type: Class
subclass of: monocarboxylic acid
subclass of: food additive
subclass of: Restriction
  on property: has role
  some values from: protic solvent
subclass of: Restriction
  on property: has role
  some values from: food acidity regulator
subclass of: Restriction
  on property: has role
  some values from: antimicrobial food preservative
subclass of: Restriction
  on property: has role
  some values from: Daphnia magna metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: acetate
IAO_0000115: A simple monocarboxylic acid containing two carbons.
has exact synonym: ACETIC ACID
has exact synonym: Acetic acid
has exact synonym: acetic acid
has related synonym: AcOH
has related synonym: CH3-COOH
has related synonym: CH3CO2H
has related synonym: E 260
has related synonym: E-260
has related synonym: E260
has related synonym: Essigsaeure
has related synonym: Ethanoic acid
has related synonym: Ethylic acid
has related synonym: HOAc
has related synonym: INS No. 260
has related synonym: MeCO2H
has related synonym: MeCOOH
has related synonym: Methanecarboxylic acid
has related synonym: acide acetique
has related synonym: ethoic acid

water
type: Class
subclass of: oxygen hydride
subclass of: mononuclear parent hydride
subclass of: inorganic hydroxy compound
subclass of: Restriction
  on property: has role
  some values from: amphiprotic solvent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: greenhouse gas
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydroxide
subclass of: Restriction
  on property: is conjugate base of
  some values from: oxonium
IAO_0000115: An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms.
has exact synonym: WATER
has exact synonym: Water
has exact synonym: oxidane
has exact synonym: water
has related synonym: BOUND WATER
has related synonym: H2O
has related synonym: HOH
has related synonym: Wasser
has related synonym: [OH2]
has related synonym: acqua
has related synonym: agua
has related synonym: aqua
has related synonym: dihydridooxygen
has related synonym: dihydrogen oxide
has related synonym: eau
has related synonym: hydrogen hydroxide

dioxygen
type: Class
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: diatomic oxygen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: reagent
subclass of: Restriction
  on property: has role
  some values from: anti-inflammatory drug
subclass of: Restriction
  on property: has role
  some values from: oxidising agent
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has role
  some values from: food packaging gas
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydridodioxygen(1+)
has exact synonym: dioxygen
has related synonym: Disauerstoff
has related synonym: E 948
has related synonym: E-948
has related synonym: E948
has related synonym: O2
has related synonym: OXYGEN MOLECULE
has related synonym: Oxygen
has related synonym: [OO]
has related synonym: dioxygene
has related synonym: molecular oxygen

primary alcohol
type: Class
subclass of: alcohol
IAO_0000115: A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
has exact synonym: Primary alcohol
has related synonym: 1-Alcohol
has related synonym: a primary alcohol
has related synonym: primary alcohols

formate
type: Class
subclass of: monocarboxylic acid anion
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: formic acid
IAO_0000115: A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects.
has exact synonym: formate
has related synonym: HCO2 anion
has related synonym: aminate
has related synonym: formiate
has related synonym: formic acid, ion(1-)
has related synonym: formylate
has related synonym: hydrogen carboxylate
has related synonym: methanoate

halide anion
type: Class
subclass of: monoatomic monoanion
subclass of: monovalent inorganic anion
IAO_0000115: A monoatomic monoanion resulting from the addition of an electron to any halogen atom.
has exact synonym: halide ions
has related synonym: HX
has related synonym: Halide
has related synonym: a halide anion
has related synonym: halide anions
has related synonym: halide(1-)
has related synonym: halides
has related synonym: halogen anion

hydroxide
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: water
has exact synonym: hydridooxygenate(1-)
has exact synonym: hydroxide
has exact synonym: oxidanide
has related synonym: HO-
has related synonym: HYDROXIDE ION
has related synonym: Hydroxide ion
has related synonym: OH(-)
has related synonym: OH-

haloacetic acid
type: Class
subclass of: organohalogen compound
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has functional parent
  some values from: acetic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: haloacetate(1-)
IAO_0000115: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a halogen atom.

carbon dioxide
type: Class
subclass of: gas molecular entity
subclass of: carbon oxide
subclass of: one-carbon compound
subclass of: food additive
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: anaesthetic
subclass of: Restriction
  on property: has role
  some values from: solvent
subclass of: Restriction
  on property: has role
  some values from: antagonist
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: greenhouse gas
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has role
  some values from: food packaging gas
subclass of: Restriction
  on property: has role
  some values from: food propellant
subclass of: Restriction
  on property: has role
  some values from: refrigerant
IAO_0000115: A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.
has exact synonym: CARBON DIOXIDE
has exact synonym: Carbon dioxide
has exact synonym: carbon dioxide
has exact synonym: dioxidocarbon
has exact synonym: methanedione
has related synonym: CO2
has related synonym: E 290
has related synonym: E-290
has related synonym: E290
has related synonym: R-744
has related synonym: [CO2]
has related synonym: carbonic anhydride

formaldehyde
type: Class
subclass of: aldehyde
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: disinfectant
subclass of: Restriction
  on property: has role
  some values from: carcinogenic agent
subclass of: Restriction
  on property: has role
  some values from: allergen
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: EC 3.5.1.4 (amidase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: environmental contaminant
IAO_0000115: An aldehyde resulting from the formal oxidation of methanol.
has exact synonym: FORMALDEHYDE
has exact synonym: Formaldehyde
has exact synonym: formaldehyde
has related synonym: FORMALIN
has related synonym: Formaldehyd
has related synonym: Formalin
has related synonym: Methanal
has related synonym: Methylene oxide
has related synonym: Oxomethane
has related synonym: Oxomethylene

ketone
type: Class
subclass of: carbonyl compound
IAO_0000115: A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
has exact synonym: Ketone
has exact synonym: ketones
has related synonym: Keton
has related synonym: R-CO-R'
has related synonym: a ketone
has related synonym: cetone
has related synonym: ketones

carbon monoxide
type: Class
subclass of: gas molecular entity
subclass of: carbon oxide
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: EC 1.9.3.1 (cytochrome c oxidase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: P450 inhibitor
subclass of: Restriction
  on property: has role
  some values from: probe
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: ligand
subclass of: Restriction
  on property: has role
  some values from: biomarker
subclass of: Restriction
  on property: has role
  some values from: signalling molecule
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbon monoxide(1+)
IAO_0000115: A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
has exact synonym: CARBON MONOXIDE
has exact synonym: Carbon monoxide
has exact synonym: carbon monooxide
has exact synonym: carbon monoxide
has exact synonym: carbon(II) oxide
has related synonym: C#O
has related synonym: CO
has related synonym: [CO]

aldehyde
type: Class
subclass of: carbonyl compound
subclass of: Restriction
  on property: has part
  some values from: formyl group
IAO_0000115: A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
has exact synonym: Aldehyde
has exact synonym: aldehyde
has exact synonym: aldehydes
has related synonym: Aldehyd
has related synonym: RC(=O)H
has related synonym: RCHO
has related synonym: aldehido
has related synonym: aldehidos
has related synonym: aldehydes
has related synonym: aldehydum
has related synonym: an aldehyde

organohalogen compound
type: Class
subclass of: heteroorganic entity
subclass of: halide
IAO_0000115: A compound containing at least one carbon-halogen bond (where X is a halogen atom).
has related synonym: RX
has related synonym: organic halide
has related synonym: organic halides
has related synonym: organohalogen compounds

hydrogen chloride
type: Class
subclass of: gas molecular entity
subclass of: hydrogen halide
subclass of: chlorine molecular entity
subclass of: mononuclear parent hydride
subclass of: food additive
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: chloride
subclass of: Restriction
  on property: is conjugate base of
  some values from: chloronium
IAO_0000115: A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
has exact synonym: Hydrogen chloride
has exact synonym: chlorane
has exact synonym: chloridohydrogen
has exact synonym: hydrogen chloride
has related synonym: Chlorwasserstoff
has related synonym: HCl
has related synonym: Hydrochloride
has related synonym: Hydrogenchlorid
has related synonym: Wasserstoffchlorid
has related synonym: [HCl]
has related synonym: chlorure d'hydrogene
has related synonym: cloruro de hidrogeno
has related synonym: hydrochloric acid

donor
type: Class
subclass of: chemical role
IAO_0000115: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
has exact synonym: Donor
has related synonym: Donator
has related synonym: donneur

chloride
type: Class
subclass of: halide anion
subclass of: monoatomic chlorine
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogen chloride
IAO_0000115: A halide anion formed when chlorine picks up an electron to form an an anion.
has exact synonym: Chloride
has exact synonym: chloride
has exact synonym: chloride(1-)
has related synonym: CHLORIDE ION
has related synonym: Chloride ion
has related synonym: Chloride(1-)
has related synonym: Chlorine anion
has related synonym: Cl(-)
has related synonym: Cl-

lipid
type: Class
subclass of: organic molecular entity
IAO_0000115: 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
has exact synonym: Lipid
has exact synonym: lipids

hydrogen halide
type: Class
subclass of: hydracid
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
has exact synonym: hydrogen halide
has exact synonym: hydrogen halides
has related synonym: HX
has related synonym: hydrogen halides

acyl group
type: Class
subclass of: organic group
IAO_0000115: An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
has exact synonym: acyl group
has exact synonym: alkanoyl
has related synonym: acyl groups
has related synonym: alkanoyl group
has related synonym: groupe acyle

aflatoxin
type: Class
subclass of: cyclopentafurofurochromene
subclass of: Restriction
  on property: has role
  some values from: mycotoxin
IAO_0000115: Any of a group of related and highly toxic secondary metabolites (mycotoxins) whose main structural feature is a fused coumarin-bis(dihydrofuran) ring system and which are produced by strains of the moulds Aspergillus flavus or A. parasiticus, together with further metabolites of these mycotoxins
has related synonym: aflatoxins

alkali metal atom
type: Class
subclass of: main group element atom
subclass of: metal atom
subclass of: s-block element atom
has exact synonym: alkali metals
has related synonym: Alkalimetall
has related synonym: Alkalimetalle
has related synonym: alkali metal
has related synonym: metal alcalin
has related synonym: metal alcalino
has related synonym: metales alcalinos
has related synonym: metaux alcalins

alkylating agent
type: Class
subclass of: mutagen
IAO_0000115: Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.

anion
type: Class
subclass of: ion
IAO_0000115: A monoatomic or polyatomic species having one or more elementary charges of the electron.
has exact synonym: Anion
has exact synonym: anion
has related synonym: Anionen
has related synonym: aniones
has related synonym: anions

base
type: Class
subclass of: chemical role
IAO_0000115: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
has exact synonym: Base
has exact synonym: base
has related synonym: Base1
has related synonym: Base2
has related synonym: Basen
has related synonym: Nucleobase
has related synonym: bases

cadmium atom
type: Class
subclass of: zinc group element atom
has exact synonym: cadmium
has related synonym: 48Cd
has related synonym: Cd
has related synonym: Kadmium
has related synonym: cadmio
has related synonym: cadmium

cadmium molecular entity
type: Class
subclass of: zinc group molecular entity
subclass of: Restriction
  on property: has part
  some values from: cadmium atom
has related synonym: cadmium compounds
has related synonym: cadmium molecular entities

carbon oxide
type: Class
subclass of: organic oxide
subclass of: organooxygen compound
has related synonym: carbon oxides
has related synonym: oxides of carbon

carbonyl group
type: Class
subclass of: organodiyl group
has exact synonym: carbonyl
has exact synonym: carbonyl group
has related synonym: >C=O

chloride salt
type: Class
subclass of: chlorine molecular entity
subclass of: halide salt
subclass of: Restriction
  on property: has part
  some values from: chloride
has related synonym: chloride salts
has related synonym: chlorides

chlorine atom
type: Class
subclass of: halogen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
has exact synonym: chlorine
has related synonym: 17Cl
has related synonym: Chlor
has related synonym: Cl
has related synonym: chlore
has related synonym: chlorine
has related synonym: chlorum
has related synonym: cloro

chlorine molecular entity
type: Class
subclass of: halogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: chlorine atom
IAO_0000115: A halogen molecular entity containing one or more atoms of chlorine.

chloroacetate
type: Class
subclass of: haloacetate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: chloroacetic acid
IAO_0000115: A haloacetate(1-) resulting from the deprotonation of the carboxy group of chloroacetic acid.
has exact synonym: chloroacetate
has related synonym: Chloroacetic acid ion(1-)
has related synonym: chloroacetate anion
has related synonym: chloroacetate(1-)
has related synonym: mono-chloroacetate
has related synonym: monochloroacetate anion
has related synonym: monochloroacetic acid anion

cofactor
type: Class
subclass of: biochemical role
IAO_0000115: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
has exact synonym: cofactor
has exact synonym: cofactors

molecular entity
type: Class
subclass of: chemical entity
IAO_0000115: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
has exact synonym: molecular entity
has related synonym: entidad molecular
has related synonym: entidades moleculares
has related synonym: entite moleculaire
has related synonym: molecular entities
has related synonym: molekulare Entitaet

drug
type: Class
subclass of: pharmaceutical
IAO_0000115: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
has related synonym: drugs
has related synonym: medicine

monoatomic anion
type: Class
subclass of: anion
subclass of: monoatomic ion
has related synonym: monoatomic anions

monoatomic cation
type: Class
subclass of: monoatomic ion
subclass of: cation
has related synonym: monoatomic cations

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
IAO_0000115: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
has exact synonym: enzyme inhibitor
has related synonym: enzyme inhibitors
has related synonym: inhibidor enzimatico
has related synonym: inhibidores enzimaticos
has related synonym: inhibiteur enzymatique
has related synonym: inhibiteurs enzymatiques

glucocorticoid
type: Class
subclass of: corticosteroid hormone
IAO_0000115: Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
has related synonym: glucocorticoids

chemical entity
type: Class
subclass of: object
IAO_0000115: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
has exact synonym: chemical entity

biological role
type: Class
subclass of: role
IAO_0000115: A role played by the molecular entity or part thereof within a biological context.
has related synonym: biological function

group
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: atom
IAO_0000115: A defined linked collection of atoms or a single atom within a molecular entity.
has exact synonym: group
has related synonym: Gruppe
has related synonym: Rest
has related synonym: groupe
has related synonym: grupo
has related synonym: grupos

halogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: halogen
has exact synonym: halogen molecular entity
has related synonym: halogen compounds
has related synonym: halogen molecular entities

halogen
type: Class
subclass of: nonmetal atom
subclass of: p-block element atom
has exact synonym: halogen
has exact synonym: halogens
has related synonym: Halogene
has related synonym: group 17 elements
has related synonym: group VII elements
has related synonym: halogene
has related synonym: halogenes
has related synonym: halogeno
has related synonym: halogenos

herbicide
type: Class
subclass of: pesticide
IAO_0000115: A substance used to destroy plant pests.
has related synonym: Herbizid
has related synonym: Unkrautbekaempfungsmittel
has related synonym: Unkrautvertilgungsmittel
has related synonym: Wildkrautbekaempfungsmittel
has related synonym: herbicides

organic heterocyclic compound
type: Class
subclass of: heteroorganic entity
subclass of: organic cyclic compound
subclass of: heterocyclic compound
IAO_0000115: A cyclic compound having as ring members atoms of carbon and at least of one other element.
has related synonym: organic heterocycle
has related synonym: organic heterocyclic compounds

hormone
type: Class
subclass of: molecular messenger
subclass of: agonist
IAO_0000115: Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
has related synonym: endocrine
has related synonym: hormones

hydrocarbon
type: Class
subclass of: organic fundamental parent
IAO_0000115: A compound consisting of carbon and hydrogen only.
has exact synonym: hydrocarbon
has exact synonym: hydrocarbons
has related synonym: Kohlenwasserstoff
has related synonym: Kohlenwasserstoffe
has related synonym: hidrocarburo
has related synonym: hidrocarburos
has related synonym: hydrocarbure

hydroxides
type: Class
subclass of: oxygen molecular entity
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydroxy group
IAO_0000115: Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).

oxoacid
type: Class
subclass of: hydroxides
subclass of: Restriction
  on property: has role
  some values from: Bronsted acid
IAO_0000115: A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
has exact synonym: oxoacid
has exact synonym: oxoacids
has related synonym: oxacids
has related synonym: oxiacids
has related synonym: oxo acid
has related synonym: oxy-acids
has related synonym: oxyacids

inorganic anion
type: Class
subclass of: anion
subclass of: inorganic ion
has related synonym: inorganic anions

inorganic molecular entity
type: Class
subclass of: molecular entity
IAO_0000115: A molecular entity that contains no carbon.
has related synonym: anorganische Verbindungen
has related synonym: inorganic compounds
has related synonym: inorganic entity
has related synonym: inorganic molecular entities
has related synonym: inorganics

inorganic salt
type: Class
subclass of: inorganic molecular entity
subclass of: salt
has related synonym: anorganisches Salz
has related synonym: inorganic salts

salt
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: cation
IAO_0000115: A salt is an assembly of cations and anions.
has exact synonym: salt
has related synonym: Salz
has related synonym: Salze
has related synonym: ionic compound
has related synonym: ionic compounds
has related synonym: sal
has related synonym: sales
has related synonym: salts
has related synonym: sel
has related synonym: sels

monoatomic ion
type: Class
subclass of: ion
subclass of: monoatomic entity
has related synonym: monoatomic ions

ion
type: Class
subclass of: molecular entity
IAO_0000115: A molecular entity having a net electric charge.
has exact synonym: Ion
has exact synonym: ion
has related synonym: Ionen
has related synonym: iones
has related synonym: ions

mercury atom
type: Class
subclass of: zinc group element atom
has exact synonym: mercury
has related synonym: 80Hg
has related synonym: Hg
has related synonym: Quecksilber
has related synonym: azogue
has related synonym: hydrargyrum
has related synonym: liquid silver
has related synonym: mercure
has related synonym: mercurio
has related synonym: mercury
has related synonym: quicksilver

mercury molecular entity
type: Class
subclass of: zinc group molecular entity
subclass of: Restriction
  on property: has part
  some values from: mercury atom
has related synonym: mercury compounds
has related synonym: mercury molecular entities

metabolite
type: Class
subclass of: biochemical role
IAO_0000115: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
has exact synonym: metabolite
has related synonym: metabolites
has related synonym: primary metabolites
has related synonym: secondary metabolites

metal cation
type: Class
subclass of: monoatomic cation
subclass of: inorganic cation
has related synonym: a metal cation
has related synonym: metal cations

mitochondrial respiratory-chain inhibitor
type: Class
subclass of: respiratory-chain inhibitor
has related synonym: mitochondrial electron transport chain inhibitors
has related synonym: mitochondrial electron-transport chain inhibitor
has related synonym: mitochondrial respiratory chain inhibitors

elemental molecule
type: Class
subclass of: molecule
subclass of: elemental molecular entity
IAO_0000115: A molecule all atoms of which have the same atomic number.
has related synonym: homoatomic molecule
has related synonym: homoatomic molecules

molecule
type: Class
subclass of: polyatomic entity
IAO_0000115: Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
has exact synonym: molecule
has related synonym: Molekuel
has related synonym: molecula
has related synonym: molecules
has related synonym: neutral molecular compounds

monocarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: monocarboxylic acid anion
IAO_0000115: An oxoacid containing a single carboxy group.
has related synonym: monocarboxylic acids

monoatomic monocation
type: Class
subclass of: monoatomic cation
has related synonym: monoatomic monocations
has related synonym: monovalent inorganic cations

mutagen
type: Class
subclass of: genotoxin
IAO_0000115: An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
has related synonym: mutagene
has related synonym: mutagenes
has related synonym: mutagenic agent
has related synonym: mutageno
has related synonym: mutagenos
has related synonym: mutagens

mycotoxin
type: Class
subclass of: toxin
subclass of: fungal metabolite
IAO_0000115: Poisonous substance produced by fungi.
has related synonym: fungal toxins
has related synonym: mycotoxins

neurotransmitter
type: Class
subclass of: molecular messenger
IAO_0000115: An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
has related synonym: neurotransmitters

nitrogen atom
type: Class
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has exact synonym: nitrogen
has related synonym: 7N
has related synonym: N
has related synonym: Stickstoff
has related synonym: azote
has related synonym: nitrogen
has related synonym: nitrogeno

nonmetal atom
type: Class
subclass of: atom
has exact synonym: nonmetal
has related synonym: Nichtmetall
has related synonym: Nichtmetalle
has related synonym: no metal
has related synonym: no metales
has related synonym: non-metal
has related synonym: non-metaux
has related synonym: nonmetal
has related synonym: nonmetals

organic anion
type: Class
subclass of: anion
subclass of: organic ion
IAO_0000115: Any organic ion with a net negative charge.
has related synonym: organic anions

organic cation
type: Class
subclass of: organic ion
subclass of: cation
IAO_0000115: Any organic ion with a net positive charge.
has related synonym: organic cations

organic ion
type: Class
subclass of: ion
subclass of: organic molecular entity
has related synonym: organic ions

organic oxide
type: Class
subclass of: oxide
subclass of: organic molecule
IAO_0000115: An oxide in which the oxygen atom is bonded to a carbon atom.
has related synonym: organic oxides

oxide
type: Class
subclass of: oxygen molecular entity
subclass of: heteroatomic molecular entity
IAO_0000115: An oxide is a chemical compound of oxygen with other chemical elements.
has exact synonym: oxide
has related synonym: oxides

oxygen atom
type: Class
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has exact synonym: oxygen
has related synonym: 8O
has related synonym: O
has related synonym: Sauerstoff
has related synonym: oxigeno
has related synonym: oxygen
has related synonym: oxygene

oxygen molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: oxygen atom
has exact synonym: oxygen molecular entity
has related synonym: oxygen molecular entities

pesticide
type: Class
subclass of: application
IAO_0000115: Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
has exact synonym: pesticide
has related synonym: Pestizid
has related synonym: Pestizide
has related synonym: pesticides

polyketide
type: Class
subclass of: organooxygen compound
IAO_0000115: Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides.
has exact synonym: polyketide
has related synonym: polyketides

sodium atom
type: Class
subclass of: alkali metal atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
has exact synonym: sodium
has related synonym: 11Na
has related synonym: Na
has related synonym: Natrium
has related synonym: natrium
has related synonym: sodio
has related synonym: sodium

sodium chloride
type: Class
subclass of: inorganic chloride
subclass of: inorganic sodium salt
subclass of: Restriction
  on property: has role
  some values from: emetic
subclass of: Restriction
  on property: has role
  some values from: flame retardant
IAO_0000115: An inorganic chloride salt having sodium(1+) as the counterion.
has exact synonym: sodium chloride
has related synonym: Kochsalz
has related synonym: NaCl
has related synonym: Natriumchlorid
has related synonym: chlorure de sodium
has related synonym: cloruro sodico
has related synonym: common salt
has related synonym: halite
has related synonym: natrii chloridum
has related synonym: rock salt
has related synonym: salt
has related synonym: table salt

sodium molecular entity
type: Class
subclass of: alkali metal molecular entity
subclass of: Restriction
  on property: has part
  some values from: sodium atom
has related synonym: sodium compounds
has related synonym: sodium molecular entities

sodium salt
type: Class
subclass of: sodium molecular entity
subclass of: alkali metal salt
subclass of: Restriction
  on property: has part
  some values from: sodium(1+)
IAO_0000115: Any alkali metal salt having sodium(1+) as the cation.
has related synonym: Natriumsalz
has related synonym: Natriumsalze
has related synonym: sodium salts

steroid hormone
type: Class
subclass of: steroid
subclass of: Restriction
  on property: has role
  some values from: hormone
IAO_0000115: Any steroid that acts as hormone.
has related synonym: Steroidhormon
has related synonym: Steroidhormone
has related synonym: hormona esteroide
has related synonym: hormonas esteroideas
has related synonym: hormone steroide
has related synonym: hormones steroides
has related synonym: steroid hormones

tertiary alcohol
type: Class
subclass of: alcohol
IAO_0000115: A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it.
has exact synonym: tertiary alcohol
has related synonym: tertiary alcohols

tetracyclines
type: Class
subclass of: polyketide
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has parent hydride
  some values from: tetracene
IAO_0000115: A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups.

toxin
type: Class
subclass of: metabolite
subclass of: poison
IAO_0000115: Poisonous substance produced by a biological organism such as a microbe, animal or plant.
has exact synonym: toxin
has related synonym: toxins

micronutrient
type: Class
subclass of: nutrient
IAO_0000115: Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
has related synonym: micronutrients
has related synonym: trace elements

transition element atom
type: Class
subclass of: metal atom
IAO_0000115: An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.
has exact synonym: transition element
has related synonym: Uebergangselement
has related synonym: Uebergangsmetalle
has related synonym: metal de transicion
has related synonym: metal de transition
has related synonym: metales de transicion
has related synonym: metaux de transition
has related synonym: transition element
has related synonym: transition elements
has related synonym: transition metal
has related synonym: transition metals

univalent carboacyl group
type: Class
subclass of: carboacyl group
IAO_0000115: A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
has related synonym: univalent acyl group
has related synonym: univalent carboacyl groups
has related synonym: univalent carboxylic acyl groups

zwitterion
type: Class
subclass of: dipolar compound
IAO_0000115: A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
has exact synonym: zwitterion
has exact synonym: zwitterions
has related synonym: compose zwitterionique
has related synonym: compuestos zwitterionicos
has related synonym: zwitteriones
has related synonym: zwitterionic compounds

carbon atom
type: Class
subclass of: nonmetal atom
subclass of: carbon group element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has exact synonym: carbon
has related synonym: 6C
has related synonym: C
has related synonym: Carbon
has related synonym: Kohlenstoff
has related synonym: carbon
has related synonym: carbone
has related synonym: carbonium
has related synonym: carbono

chloroacetic acid
type: Class
subclass of: haloacetic acid
subclass of: chlorocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: alkylating agent
subclass of: Restriction
  on property: has role
  some values from: herbicide
subclass of: Restriction
  on property: is conjugate acid of
  some values from: chloroacetate
IAO_0000115: A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
has exact synonym: Chloroacetic acid
has exact synonym: chloroacetic acid
has related synonym: 2-chloro-acetic acid
has related synonym: 2-chloro-ethanoic acid
has related synonym: 2-chloroacetic acid
has related synonym: Acide chloracetique
has related synonym: Acide chloroacetique
has related synonym: Acide monochloracetique
has related synonym: CAA
has related synonym: Chloroethanoic acid
has related synonym: Monochloressigsaeure
has related synonym: alpha-chloro-acetic acid
has related synonym: chloracetic acid
has related synonym: monochloroacetic acid
has related synonym: monochloroethanoic acid

tetracycline
type: Class
subclass of: tertiary alpha-hydroxy ketone
subclass of: tetracyclines
subclass of: Restriction
  on property: has role
  some values from: antiprotozoal drug
subclass of: Restriction
  on property: has role
  some values from: antibacterial drug
subclass of: Restriction
  on property: has role
  some values from: protein synthesis inhibitor
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tetracycline(1-)
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tetracycline zwitterion
IAO_0000115: A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.
has exact synonym: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
has exact synonym: TETRACYCLINE
has exact synonym: Tetracycline
has exact synonym: tetracycline
has related synonym: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
has related synonym: Abramycin
has related synonym: Achromycin
has related synonym: Anhydrotetracycline
has related synonym: Deschlorobiomycin
has related synonym: Liquamycin
has related synonym: Tetracyclin
has related synonym: Tetrazyklin
has related synonym: Tsiklomitsin
has related synonym: tetracycline
has related synonym: tetracyclinum

carboxylic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carboxylic acid
IAO_0000115: The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
has related synonym: a carboxylate
has related synonym: carboxylic acid anions
has related synonym: carboxylic anions

sodium(1+)
type: Class
subclass of: monoatomic monocation
subclass of: alkali metal cation
subclass of: elemental sodium
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: human metabolite
IAO_0000115: A monoatomic monocation obtained from sodium.
has exact synonym: sodium cation
has exact synonym: sodium(1+)
has exact synonym: sodium(1+) ion
has exact synonym: sodium(I) cation
has related synonym: Na(+)
has related synonym: Na+
has related synonym: SODIUM ION

oxonium
type: Class
subclass of: oxygen hydride
subclass of: onium cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: water
has exact synonym: aquahydrogen(1+)
has exact synonym: oxidanium
has exact synonym: oxonium
has exact synonym: trihydridooxygen(1+)
has related synonym: H3O(+)
has related synonym: Hydronium cation
has related synonym: Hydronium ion
has related synonym: [OH3](+)

hydridodioxygen(1+)
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dioxygen
has exact synonym: dioxidenium
has exact synonym: hydridodioxygen(1+)
has related synonym: HO2(+)
has related synonym: HOO(+)
has related synonym: [HO2](+)

acetate
type: Class
subclass of: monocarboxylic acid anion
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: acetic acid
IAO_0000115: A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
has exact synonym: acetate
has related synonym: ACETATE ION
has related synonym: Azetat
has related synonym: CH3-COO(-)
has related synonym: Ethanoat
has related synonym: MeCO2 anion
has related synonym: acetic acid, ion(1-)
has related synonym: ethanoate

formic acid
type: Class
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: protic solvent
subclass of: Restriction
  on property: has role
  some values from: astringent
subclass of: Restriction
  on property: is conjugate acid of
  some values from: formate
IAO_0000115: The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
has exact synonym: FORMIC ACID
has exact synonym: Formic acid
has exact synonym: formic acid
has related synonym: Acide formique
has related synonym: Ameisensaeure
has related synonym: H-COOH
has related synonym: HCO2H
has related synonym: HCOOH
has related synonym: Methanoic acid
has related synonym: aminic acid
has related synonym: bilorin
has related synonym: formylic acid
has related synonym: hydrogen carboxylic acid
has related synonym: methoic acid

alcohol
type: Class
subclass of: organic hydroxy compound
subclass of: alcoholic beverage
IAO_0000115: A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
has exact synonym: Alcohol
has exact synonym: alcohols
has related synonym: an alcohol

tetracene
type: Class
subclass of: acene
subclass of: tetracenes
IAO_0000115: An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement.
has exact synonym: tetracene
has related synonym: 2,3-benzanthracene
has related synonym: benz[b]anthracene
has related synonym: naphthacene

application
type: Class
subclass of: role
IAO_0000115: Intended use of the molecular entity or part thereof by humans.

fundamental particle
type: Class
subclass of: subatomic particle
IAO_0000115: A particle not known to have substructure.
has exact synonym: elementary particle
has related synonym: elementary particles

monoatomic entity
type: Class
subclass of: elemental molecular entity
IAO_0000115: A monoatomic entity is a molecular entity consisting of a single atom.
has related synonym: atomic entity
has related synonym: monoatomic entities

inorganic hydride
type: Class
subclass of: inorganic molecular entity
subclass of: hydrides
has related synonym: inorganic hydrides

organic fundamental parent
type: Class
subclass of: organic hydride
subclass of: organic molecular entity
IAO_0000115: An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
has related synonym: organic fundamental parents
has related synonym: organic parent hydrides

inorganic group
type: Class
subclass of: group
IAO_0000115: Any substituent group which does not contain carbon.
has related synonym: inorganic groups

organic group
type: Class
subclass of: molecular entity
subclass of: group
subclass of: Restriction
  on property: is substituent group from
  some values from: organic molecular entity
IAO_0000115: Any substituent group or skeleton containing carbon.
has related synonym: organic groups

organyl group
type: Class
subclass of: organic univalent group
IAO_0000115: Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
has exact synonym: organyl group
has exact synonym: organyl groups
has related synonym: groupe organyle
has related synonym: grupo organilo
has related synonym: grupos organilo

atom
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: electron
subclass of: Restriction
  on property: has part
  some values from: atomic nucleus
IAO_0000115: A chemical entity constituting the smallest component of an element having the chemical properties of the element.
has exact synonym: atom
has related synonym: atome
has related synonym: atomo
has related synonym: atoms
has related synonym: atomus
has related synonym: element
has related synonym: elements

atomic nucleus
type: Class
subclass of: nuclear particle
subclass of: Restriction
  on property: has part
  some values from: nucleon
IAO_0000115: A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
has exact synonym: nucleus
has related synonym: Atomkern
has related synonym: Kern
has related synonym: noyau
has related synonym: noyau atomique
has related synonym: nuclei
has related synonym: nucleo
has related synonym: nucleo atomico
has related synonym: nucleus atomi

nucleon
type: Class
subclass of: baryon
subclass of: nuclear particle
IAO_0000115: Heavy nuclear particle: proton or neutron.
has exact synonym: nucleon
has related synonym: Nukleon
has related synonym: Nukleonen
has related synonym: nucleons

elemental molecular entity
type: Class
subclass of: molecular entity
subclass of: mineral
IAO_0000115: A molecular entity all atoms of which have the same atomic number.
has related synonym: homoatomic entity
has related synonym: homoatomic molecular entities
has related synonym: homoatomic molecular entity

elemental oxygen
type: Class
subclass of: inorganic molecular entity
subclass of: oxygen molecular entity
subclass of: elemental molecular entity

diatomic oxygen
type: Class
subclass of: elemental oxygen

polyatomic anion
type: Class
subclass of: anion
subclass of: polyatomic ion
IAO_0000115: An anion consisting of more than one atom.
has related synonym: polyatomic anions

molecular messenger
type: Class
subclass of: biological role
has related synonym: chemical messenger

antimicrobial agent
type: Class
subclass of: biological role
IAO_0000115: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
has related synonym: Antibiotika
has related synonym: Antibiotikum
has related synonym: antibiotic
has related synonym: antibiotics
has related synonym: antibiotique
has related synonym: antimicrobial
has related synonym: antimicrobial agents
has related synonym: antimicrobials
has related synonym: microbicide
has related synonym: microbicides

antibacterial agent
type: Class
subclass of: antimicrobial agent
IAO_0000115: A substance (or active part thereof) that kills or slows the growth of bacteria.
has related synonym: antibacterial agents
has related synonym: antibacterials
has related synonym: bactericide
has related synonym: bactericides

nutrient
type: Class
subclass of: food component
IAO_0000115: A nutrient is a food component that an organism uses to survive and grow.
has related synonym: nutrients

heteroorganic entity
type: Class
subclass of: organic molecular entity
IAO_0000115: A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
has related synonym: heteroorganic entities
has related synonym: organoelement compounds

food
type: Class
subclass of: physiological role
subclass of: Restriction
  on property: has part
  some values from: food component
IAO_0000115: Any material that can be ingested by an organism.
has related synonym: food material
has related synonym: food materials
has related synonym: food role
has related synonym: foods
has related synonym: foodstuff
has related synonym: foodstuffs

fuel
type: Class
subclass of: application
IAO_0000115: An energy-rich substance that can be transformed with release of usable energy.

alkali metal molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: alkali metal atom
IAO_0000115: A molecular entity containing one or more atoms of an alkali metal.
has related synonym: alkali metal molecular entities

pnictogen
type: Class
subclass of: p-block element atom
IAO_0000115: Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
has exact synonym: pnictogens
has related synonym: group 15 elements
has related synonym: group V elements
has related synonym: nitrogenoideos
has related synonym: nitrogenoides
has related synonym: pnictogene
has related synonym: pnictogenes

pnictogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: pnictogen
IAO_0000115: A p-block molecular entity containing any pnictogen.
has exact synonym: pnictogen molecular entity
has related synonym: pnictogen molecular entities

chalcogen
type: Class
subclass of: p-block element atom
IAO_0000115: Any p-block element belonging to the group 16 family of the periodic table.
has exact synonym: chalcogen
has exact synonym: chalcogens
has related synonym: Chalkogen
has related synonym: Chalkogene
has related synonym: anfigeno
has related synonym: anfigenos
has related synonym: calcogeno
has related synonym: calcogenos
has related synonym: chalcogene
has related synonym: chalcogenes
has related synonym: group 16 elements
has related synonym: group VI elements

chalcogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: chalcogen
IAO_0000115: Any p-block molecular entity containing a chalcogen.
has exact synonym: chalcogen molecular entity
has related synonym: chalcogen compounds
has related synonym: chalcogen molecular entities

carbon group element atom
type: Class
subclass of: p-block element atom
has exact synonym: group 14 elements
has related synonym: carbon group element
has related synonym: carbon group elements
has related synonym: carbonoides
has related synonym: cristallogene
has related synonym: cristallogenes
has related synonym: group IV elements

main group element atom
type: Class
subclass of: atom
IAO_0000115: An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
has exact synonym: main group elements
has related synonym: Hauptgruppenelement
has related synonym: Hauptgruppenelemente
has related synonym: main group element

zinc group element atom
type: Class
subclass of: d-block element atom
has exact synonym: group 12 elements
has related synonym: zinc group element
has related synonym: zinc group elements

hydracid
type: Class
subclass of: hydrogen molecular entity
subclass of: Restriction
  on property: has role
  some values from: Bronsted acid
IAO_0000115: A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
has exact synonym: hydracid
has related synonym: hydracids

monoatomic monoanion
type: Class
subclass of: monoatomic anion
subclass of: monoanion
has related synonym: monoatomic monoanions

elemental chlorine
type: Class
subclass of: chlorine molecular entity
subclass of: elemental halogen

monoatomic chlorine
type: Class
subclass of: elemental chlorine
subclass of: monoatomic halogen
has related synonym: atomic chlorine

monoatomic halogen
type: Class
subclass of: monoatomic entity
has related synonym: monoatomic halogens

elemental halogen
type: Class
subclass of: elemental molecular entity
has exact synonym: elemental halogen
has related synonym: elemental halogens

transition element molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: transition element atom
IAO_0000115: A molecular entity containing one or more atoms of a transition element.
has related synonym: transition element molecular entities
has related synonym: transition metal molecular entity

alkali metal cation
type: Class
subclass of: metal cation
has related synonym: alkali metal cations

metal atom
type: Class
subclass of: atom
IAO_0000115: An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
has related synonym: elemental metal
has related synonym: elemental metals
has related synonym: metal element
has related synonym: metal elements
has related synonym: metals

s-block element atom
type: Class
subclass of: atom
has related synonym: s-block element
has related synonym: s-block elements

p-block element atom
type: Class
subclass of: main group element atom
IAO_0000115: Any main group element atom belonging to the p-block of the periodic table.
has related synonym: p-block element
has related synonym: p-block elements

d-block element atom
type: Class
subclass of: transition element atom
has related synonym: d-block element
has related synonym: d-block elements

carboxylic acid
type: Class
subclass of: carbon oxoacid
subclass of: carbonyl compound
subclass of: organic acid
subclass of: Restriction
  on property: has part
  some values from: carboxy group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carboxylic acid anion
IAO_0000115: A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
has exact synonym: carboxylic acid
has exact synonym: carboxylic acids
has related synonym: Carbonsaeure
has related synonym: Carbonsaeuren
has related synonym: Karbonsaeure
has related synonym: RC(=O)OH
has related synonym: acide carboxylique
has related synonym: acides carboxyliques
has related synonym: acido carboxilico
has related synonym: acidos carboxilicos

main group molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: main group element atom
IAO_0000115: A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
has related synonym: main group compounds
has related synonym: main group molecular entities

carbon group molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon group element atom
has exact synonym: carbon group molecular entity
has related synonym: carbon group molecular entities

cyclic compound
type: Class
subclass of: molecule
IAO_0000115: Any molecule that consists of a series of atoms joined together to form a ring.
has related synonym: cyclic compounds

homocyclic compound
type: Class
subclass of: cyclic compound
IAO_0000115: A cyclic compound having as ring members atoms of the same element only.
has exact synonym: homocyclic compound
has exact synonym: homocyclic compounds
has related synonym: isocyclic compounds

carbocyclic compound
type: Class
subclass of: homocyclic compound
subclass of: organic cyclic compound
IAO_0000115: A homocyclic compound in which all of the ring members are carbon atoms.
has exact synonym: carbocyclic compound
has exact synonym: carbocyclic compounds
has related synonym: carbocycle

hydrogen molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydrogen atom
has related synonym: hydrogen compounds
has related synonym: hydrogen molecular entities

polycyclic compound
type: Class
subclass of: cyclic compound
has related synonym: polycyclic compounds

ortho-fused compound
type: Class
subclass of: fused compound
IAO_0000115: A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms.
has exact synonym: ortho-fused polycyclic compounds
has related synonym: ortho-fused compounds

aromatic compound
type: Class
subclass of: cyclic compound
IAO_0000115: A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
has exact synonym: aromatic compounds
has exact synonym: aromatic molecular entity
has related synonym: aromatics
has related synonym: aromatische Verbindungen

arene
type: Class
subclass of: organic aromatic compound
subclass of: cyclic hydrocarbon
IAO_0000115: Any monocyclic or polycyclic aromatic hydrocarbon.
has exact synonym: arene
has exact synonym: arenes
has related synonym: aromatic hydrocarbons

organic aromatic compound
type: Class
subclass of: aromatic compound
subclass of: organic cyclic compound
has related synonym: organic aromatic compounds

cyclic hydrocarbon
type: Class
subclass of: hydrocarbon
subclass of: carbocyclic compound
has exact synonym: cyclic hydrocarbon
has related synonym: cyclic hydrocarbons

polycyclic hydrocarbon
type: Class
subclass of: cyclic hydrocarbon
subclass of: carbopolycyclic compound
has exact synonym: polycyclic hydrocarbon
has exact synonym: polycyclic hydrocarbons

heteropolycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: heterocyclic compound
IAO_0000115: A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.
has exact synonym: heteropolycyclic compounds
has related synonym: polyheterocyclic compounds

zinc group molecular entity
type: Class
subclass of: d-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: zinc group element atom
has related synonym: zinc group molecular entities

s-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: s-block element atom
IAO_0000115: An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
has exact synonym: s-block molecular entity
has related synonym: s-block compounds
has related synonym: s-block molecular entities

p-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: p-block element atom
IAO_0000115: A main group molecular entity that contains one or more atoms of a p-block element.
has related synonym: p-block compounds
has related synonym: p-block molecular entities
has related synonym: p-block molecular entitiy

d-block molecular entity
type: Class
subclass of: transition element molecular entity
subclass of: Restriction
  on property: has part
  some values from: d-block element atom
IAO_0000115: A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.
has exact synonym: d-block molecular entity
has related synonym: d-block compounds
has related synonym: d-block molecular entities

hydrides
type: Class
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
IAO_0000115: Hydrides are chemical compounds of hydrogen with other chemical elements.

oxygen hydride
type: Class
subclass of: chalcogen hydride
has exact synonym: oxygen hydride
has related synonym: hydrides of oxygen
has related synonym: oxygen hydrides

organic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: organic molecular entity
IAO_0000115: An organic compound having at least one hydroxy group attached to a carbon atom.
has exact synonym: hydroxy compounds
has related synonym: organic alcohol
has related synonym: organic hydroxy compounds

organic cyclic compound
type: Class
subclass of: cyclic compound
subclass of: organic molecule
IAO_0000115: Any organic molecule that consists of atoms connected in the form of a ring.
has related synonym: organic cyclic compounds

benzenoid aromatic compound
type: Class
subclass of: carbocyclic compound
subclass of: organic aromatic compound
has related synonym: benzenoid aromatic compounds
has related synonym: benzenoid compound

polycyclic arene
type: Class
subclass of: arene
subclass of: polycyclic hydrocarbon
subclass of: Restriction
  on property: has role
  some values from: endocrine disruptor
subclass of: Restriction
  on property: has role
  some values from: carcinogenic agent
IAO_0000115: A polycyclic aromatic hydrocarbon.
has related synonym: PAH
has related synonym: PAHs
has related synonym: polycyclic arenes
has related synonym: polycyclic aromatic hydrocarbons

reagent
type: Class
subclass of: application
IAO_0000115: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
has exact synonym: reagent
has related synonym: reactif
has related synonym: reactivo
has related synonym: reagents

macronutrient
type: Class
subclass of: nutrient
IAO_0000115: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
has related synonym: macronutrients

halide salt
type: Class
subclass of: salt
subclass of: halide
subclass of: Restriction
  on property: has part
  some values from: halide anion
has related synonym: halide salts
has related synonym: halides

inhibitor
type: Class
subclass of: biological role
IAO_0000115: A substance that diminishes the rate of a chemical reaction.
has exact synonym: inhibitor
has related synonym: inhibidor
has related synonym: inhibiteur
has related synonym: inhibitors

fused compound
type: Class
subclass of: polycyclic compound
has related synonym: fused compounds
has related synonym: fused polycyclic compounds
has related synonym: fused-ring polycyclic compound
has related synonym: fused-ring polycyclic compounds
has related synonym: polycyclic fused-ring compounds

carbopolycyclic compound
type: Class
subclass of: carbocyclic compound
subclass of: homopolycyclic compound
IAO_0000115: A polyclic compound in which all of the ring members are carbon atoms.
has related synonym: carbopolycyclic compounds

homopolycyclic compound
type: Class
subclass of: homocyclic compound
subclass of: polycyclic compound
has related synonym: homopolycyclic compounds

ortho-fused polycyclic arene
type: Class
subclass of: polycyclic arene
subclass of: ortho-fused polycyclic hydrocarbon
has related synonym: ortho-fused polycyclic arenes

acene
type: Class
subclass of: ortho-fused polycyclic arene
subclass of: acenes
IAO_0000115: A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement.
has exact synonym: acene
has exact synonym: acenes
has related synonym: Acen
has related synonym: Azen
has related synonym: polyacenes

steroid
type: Class
subclass of: lipid
subclass of: organic polycyclic compound
IAO_0000115: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene, so may be considered as triterpenoids.
has exact synonym: Steroid
has exact synonym: steroids
has related synonym: a steroid

oxoanion
type: Class
subclass of: oxide
subclass of: polyatomic anion
IAO_0000115: An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
has exact synonym: oxoanion
has related synonym: oxoacid anions
has related synonym: oxoanions

ortho-fused polycyclic hydrocarbon
type: Class
subclass of: ortho-fused compound
has exact synonym: ortho-fused polycyclic hydrocarbon
has related synonym: ortho-fused polycyclic hydrocarbons

antiinfective agent
type: Class
subclass of: drug
IAO_0000115: A substance used in the prophylaxis or therapy of infectious diseases.
has related synonym: anti-infective agents
has related synonym: anti-infective drugs
has related synonym: antiinfective agents
has related synonym: antiinfective drug

antiparasitic agent
type: Class
subclass of: antiinfective agent
IAO_0000115: A substance used to treat or prevent parasitic infections.
has related synonym: antiparasitic drugs
has related synonym: antiparasitics
has related synonym: parasiticides

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: anti-inflammatory agent
IAO_0000115: A substance that reduces or suppresses inflammation.
has related synonym: anti-inflammatory drugs
has related synonym: antiinflammatory agent
has related synonym: antiinflammatory drug
has related synonym: antiinflammatory drugs

alkali metal salt
type: Class
subclass of: salt
subclass of: alkali metal molecular entity
has related synonym: alkali metal salts

cardiovascular drug
type: Class
subclass of: drug
IAO_0000115: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
has related synonym: cardiovascular agent
has related synonym: cardiovascular drugs

carbon oxoacid
type: Class
subclass of: oxoacid
subclass of: organooxygen compound
has related synonym: carbon oxoacids
has related synonym: oxoacids of carbon

vasodilator agent
type: Class
subclass of: cardiovascular drug
IAO_0000115: A drug used to cause dilation of the blood vessels.
has related synonym: vasodilator
has related synonym: vasodilator agents

monocarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: monocarboxylic acid
IAO_0000115: A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.
has related synonym: Carboxylate
has related synonym: Monocarboxylate
has related synonym: a monocarboxylate
has related synonym: monocarboxylates
has related synonym: monocarboxylic acid anions

antiprotozoal drug
type: Class
subclass of: antiparasitic agent
subclass of: antimicrobial drug
IAO_0000115: Any antimicrobial drug which is used to treat or prevent protozoal infections.
has related synonym: antiprotozoal agent
has related synonym: antiprotozoal agents
has related synonym: antiprotozoal drugs

antimicrobial drug
type: Class
subclass of: antimicrobial agent
subclass of: antiinfective agent
IAO_0000115: A drug used to treat or prevent microbial infections.
has related synonym: antimicrobial drugs

antibacterial drug
type: Class
subclass of: antibacterial agent
subclass of: antimicrobial drug
IAO_0000115: A drug used to treat or prevent bacterial infections.
has related synonym: antibacterial drugs

inorganic chloride
type: Class
subclass of: chloride salt
subclass of: inorganic salt
has related synonym: inorganic chloride salt
has related synonym: inorganic chloride salts
has related synonym: inorganic chlorides

lepton
type: Class
subclass of: fundamental particle
subclass of: fermion
IAO_0000115: Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
has related synonym: leptons

baryon
type: Class
subclass of: fermion
subclass of: hadron
IAO_0000115: Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
has related synonym: baryons

fermion
type: Class
subclass of: subatomic particle
IAO_0000115: Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
has exact synonym: fermion
has related synonym: fermions

subatomic particle
type: Class
subclass of: material entity
IAO_0000115: A particle smaller than an atom.
has related synonym: subatomic particles

composite particle
type: Class
subclass of: subatomic particle
IAO_0000115: A subatomic particle known to have substructure (i.e. consisting of smaller particles).
has related synonym: composite particles

hadron
type: Class
subclass of: composite particle
IAO_0000115: Hadron is a subatomic particle which experiences the strong force.
has related synonym: hadrons

nuclear particle
type: Class
subclass of: subatomic particle
IAO_0000115: A nucleus or any of its constituents in any of their energy states.
has exact synonym: nuclear particle

polyatomic entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: group
IAO_0000115: Any molecular entity consisting of more than one atom.
has related synonym: polyatomic entities

polyatomic ion
type: Class
subclass of: ion
subclass of: polyatomic entity
IAO_0000115: An ion consisting of more than one atom.
has related synonym: polyatomic ions

carbonyl compound
type: Class
subclass of: organic oxo compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
IAO_0000115: Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
has exact synonym: carbonyl compounds

organic oxo compound
type: Class
subclass of: organic molecule
subclass of: Restriction
  on property: has part
  some values from: oxo group
IAO_0000115: Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
has exact synonym: oxo compounds
has related synonym: organic oxo compounds

organochlorine compound
type: Class
subclass of: organohalogen compound
subclass of: chlorine molecular entity
IAO_0000115: An organochlorine compound is a compound containing at least one carbon-chlorine bond.
has exact synonym: organochlorine compound
has related synonym: an organochlorine molecule
has related synonym: chloroorganic compounds
has related synonym: chlororganische Verbindungen
has related synonym: organochloride
has related synonym: organochloride compound
has related synonym: organochloride compounds
has related synonym: organochlorides
has related synonym: organochlorine compounds

chlorocarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: organochlorine compound
IAO_0000115: A carboxylic acid containing at least one chloro group.
has related synonym: chlorocarboxylic acids

corticosteroid hormone
type: Class
subclass of: steroid hormone
subclass of: corticosteroid
IAO_0000115: Any of a class of steroid hormones that are produced in the adrenal cortex.
has related synonym: adrenal cortex hormones
has related synonym: corticosteroid hormones

monoanion
type: Class
subclass of: anion
has related synonym: monoanions

chalcogen hydride
type: Class
subclass of: inorganic hydride
subclass of: chalcogen molecular entity
has exact synonym: chalcogen hydride
has related synonym: chalcogen hydrides

inorganic ion
type: Class
subclass of: inorganic molecular entity
subclass of: ion
has related synonym: inorganic ions

inorganic cation
type: Class
subclass of: inorganic ion
subclass of: cation
has related synonym: inorganic cations

cation
type: Class
subclass of: ion
IAO_0000115: A monoatomic or polyatomic species having one or more elementary charges of the proton.
has exact synonym: Cation
has exact synonym: cation
has related synonym: Kation
has related synonym: Kationen
has related synonym: cationes
has related synonym: cations

organochalcogen compound
type: Class
subclass of: heteroorganic entity
subclass of: chalcogen molecular entity
IAO_0000115: An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
has exact synonym: organochalcogen compound
has related synonym: organochalcogen compounds

organooxygen compound
type: Class
subclass of: oxygen molecular entity
subclass of: organochalcogen compound
IAO_0000115: An organochalcogen compound containing at least one carbon-oxygen bond.
has exact synonym: organooxygen compound
has related synonym: organooxygen compounds

organic hydride
type: Class
subclass of: hydrides
has related synonym: organic hydrides

mononuclear parent hydride
type: Class
subclass of: hydrides
has exact synonym: mononuclear parent hydrides
has related synonym: mononuclear hydride
has related synonym: mononuclear hydrides

elemental sodium
type: Class
subclass of: sodium molecular entity

acid
type: Class
subclass of: chemical role
IAO_0000115: An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
has exact synonym: Acid
has exact synonym: acid
has related synonym: Saeure
has related synonym: Saeuren
has related synonym: acide
has related synonym: acido
has related synonym: acids

heteroatomic molecular entity
type: Class
subclass of: polyatomic entity
IAO_0000115: A molecular entity consisting of two or more chemical elements.
has related synonym: chemical compound
has related synonym: heteroatomic molecular entities

halide
type: Class
subclass of: halogen molecular entity
subclass of: heteroatomic molecular entity
IAO_0000115: Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements.
has related synonym: halides

carboacyl group
type: Class
subclass of: acyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carboxylic acid
IAO_0000115: A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.
has exact synonym: carboacyl groups
has exact synonym: carboxylic acyl group
has related synonym: carboxylic acyl groups

oxacycle
type: Class
subclass of: organic heterocyclic compound
subclass of: organooxygen compound
IAO_0000115: Any organic heterocyclic compound containing at least one ring oxygen atom.
has related synonym: heterocyclic organooxygen compounds
has related synonym: organooxygen heterocyclic compounds
has related synonym: oxacycles

organic heteropentacyclic compound
type: Class
subclass of: organic heteropolycyclic compound
has related synonym: organic heteropentacyclic compounds

organic heteropolycyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteropolycyclic compound
has related synonym: organic heteropolycyclic compounds

electron-transport chain inhibitor
type: Class
subclass of: pathway inhibitor

respiratory-chain inhibitor
type: Class
subclass of: electron-transport chain inhibitor

EC 1.9.3.1 (cytochrome c oxidase) inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
IAO_0000115: An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).
has related synonym: CcO inhibitor
has related synonym: EC 1.9.3.1 (cytochrome c oxidase) inhibitors
has related synonym: EC 1.9.3.1 inhibitor
has related synonym: EC 1.9.3.1 inhibitors
has related synonym: NADH cytochrome c oxidase inhibitor
has related synonym: NADH cytochrome c oxidase inhibitors
has related synonym: Warburg's respiratory enzyme inhibitor
has related synonym: Warburg's respiratory enzyme inhibitors
has related synonym: complex IV (mitochondrial electron transport) inhibitor
has related synonym: complex IV (mitochondrial electron transport) inhibitors
has related synonym: cytochrome a3 inhibitor
has related synonym: cytochrome a3 inhibitors
has related synonym: cytochrome aa3 inhibitor
has related synonym: cytochrome aa3 inhibitors
has related synonym: cytochrome c oxidase (EC 1.9.3.1) inhibitor
has related synonym: cytochrome c oxidase (EC 1.9.3.1) inhibitors
has related synonym: cytochrome c oxidase inhibitor
has related synonym: cytochrome c oxidase inhibitors
has related synonym: cytochrome oxidase inhibitor
has related synonym: cytochrome oxidase inhibitors
has related synonym: cytochrome-c oxidase inhibitor
has related synonym: cytochrome-c oxidase inhibitors
has related synonym: ferrocytochrome c oxidase inhibitor
has related synonym: ferrocytochrome c oxidase inhibitors
has related synonym: ferrocytochrome-c:oxygen oxidoreductase inhibitor
has related synonym: ferrocytochrome-c:oxygen oxidoreductase inhibitors
has related synonym: indophenol oxidase inhibitor
has related synonym: indophenol oxidase inhibitors
has related synonym: indophenolase inhibitor
has related synonym: indophenolase inhibitors
has related synonym: mitochondrial complex IV inhibitor
has related synonym: mitochondrial complex IV inhibitors
has related synonym: mitochondrial cytochrome-c oxidase inhibitors

inorganic sodium salt
type: Class
subclass of: inorganic salt
subclass of: sodium salt
has related synonym: inorganic sodium salts

anaesthetic
type: Class
subclass of: drug
IAO_0000115: Substance which produces loss of feeling or sensation.
has exact synonym: anaesthetic
has related synonym: Anaesthetika
has related synonym: Anaesthetikum
has related synonym: anaesthetics
has related synonym: anesthetic agent
has related synonym: anesthetic drug
has related synonym: anesthetics

Bronsted acid
type: Class
subclass of: donor
subclass of: acid
IAO_0000115: A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
has exact synonym: Bronsted acid
has related synonym: Bronsted-Saeure
has related synonym: acide de Bronsted
has related synonym: donneur d'hydron
has related synonym: hydron donor

Bronsted base
type: Class
subclass of: acceptor
subclass of: base
IAO_0000115: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
has exact synonym: Bronsted base
has related synonym: Bronsted-Base
has related synonym: accepteur d'hydron
has related synonym: base de Bronsted
has related synonym: hydron acceptor

formyl group
type: Class
subclass of: univalent carboacyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: formic acid
has exact synonym: FORMYL GROUP
has exact synonym: aldehyde group
has exact synonym: carbaldehyde
has exact synonym: formyl
has related synonym: -CH(O)
has related synonym: -CHO
has related synonym: Fo
has related synonym: H-CO-
has related synonym: methanoyl

hydroxy group
type: Class
subclass of: inorganic group
has exact synonym: HYDROXY GROUP
has exact synonym: hydroxy
has exact synonym: hydroxy group
has related synonym: -OH
has related synonym: hydroxyl
has related synonym: hydroxyl group

oxo group
type: Class
subclass of: inorganic group
has exact synonym: OXO GROUP
has exact synonym: oxo
has related synonym: =O

mineral
type: Class
subclass of: chemical substance
IAO_0000115: In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals').
has exact synonym: mineral
has related synonym: Minerale
has related synonym: minerales
has related synonym: minerals
has related synonym: mineraux

solvent
type: Class
subclass of: application
subclass of: chemical role
IAO_0000115: A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
has related synonym: Loesungsmittel
has related synonym: solvant
has related synonym: solvents

carboxy group
type: Class
subclass of: organyl group
has exact synonym: CARBOXY GROUP
has exact synonym: carboxy
has related synonym: -C(O)OH
has related synonym: -CO2H
has related synonym: -COOH
has related synonym: carboxyl group

indicator
type: Class
subclass of: application
IAO_0000115: Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.
has related synonym: Indikator

protein synthesis inhibitor
type: Class
subclass of: pathway inhibitor
IAO_0000115: A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
has related synonym: protein synthesis antagonist
has related synonym: protein synthesis antagonists
has related synonym: protein synthesis inhibitors

cyclopentafurofurochromene
type: Class
subclass of: oxacycle
subclass of: organic heteropentacyclic compound
has related synonym: cyclopentafurofurochromenes

disinfectant
type: Class
subclass of: antimicrobial agent
IAO_0000115: An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
has related synonym: Desinfektionsmittel
has related synonym: desinfectant
has related synonym: disinfectants
has related synonym: disinfecting agent

polar solvent
type: Class
subclass of: solvent
IAO_0000115: A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
has exact synonym: polar solvent
has related synonym: polar solvents

protic solvent
type: Class
subclass of: Bronsted acid
subclass of: polar solvent
IAO_0000115: A polar solvent that is capable of acting as a hydron (proton) donor.
has exact synonym: protogenic solvent

protophilic solvent
type: Class
subclass of: Bronsted base
subclass of: polar solvent
IAO_0000115: Solvent that is capable of acting as a hydron (proton) acceptor.
has exact synonym: protophilic solvent
has related synonym: HBA solvent
has related synonym: hydrogen bond acceptor solvent

amphiprotic solvent
type: Class
subclass of: protic solvent
subclass of: protophilic solvent
IAO_0000115: Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.
has exact synonym: amphiprotic solvent

agonist
type: Class
subclass of: pharmacological role
IAO_0000115: Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
has exact synonym: agonist
has related synonym: agonista
has related synonym: agoniste
has related synonym: agonists

antagonist
type: Class
subclass of: pharmacological role
IAO_0000115: Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
has exact synonym: antagonist
has related synonym: antagonista
has related synonym: antagoniste
has related synonym: antagonists

hydrogen atom
type: Class
subclass of: inorganic molecular entity
subclass of: nonmetal atom
subclass of: s-block element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has exact synonym: hydrogen
has related synonym: 1H
has related synonym: H
has related synonym: Wasserstoff
has related synonym: hidrogeno
has related synonym: hydrogen
has related synonym: hydrogene

P450 inhibitor
type: Class
subclass of: EC 1.14.14.1 (unspecific monooxygenase) inhibitor
IAO_0000115: An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
has related synonym: CYP2D6 inhbitor
has related synonym: CYP2D6 inhbitors
has related synonym: P450 inhibitors
has related synonym: cytochrome P450 inhibitor
has related synonym: cytochrome P450 inhibitors

onium compound
type: Class
subclass of: heteroatomic molecular entity

onium cation
type: Class
subclass of: onium compound
IAO_0000115: Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
has exact synonym: onium cations
has related synonym: onium cations
has related synonym: onium ion
has related synonym: onium ions

chloronium
type: Class
subclass of: onium cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogen chloride
has exact synonym: chloranium
has exact synonym: chloronium
has related synonym: H2Cl(+)
has related synonym: [ClH2](+)

probe
type: Class
subclass of: application
IAO_0000115: A role played by a molecular entity used to study the microscopic environment.

corticosteroid
type: Class
subclass of: steroid
IAO_0000115: A natural or synthetic analogue of the hormones secreted by the adrenal gland.
has related synonym: corticoides
has related synonym: corticosteroides
has related synonym: corticosteroids

organic molecular entity
type: Class
subclass of: carbon group molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon atom
IAO_0000115: Any molecular entity that contains carbon.
has related synonym: organic compounds
has related synonym: organic entity
has related synonym: organic molecular entities

genotoxin
type: Class
subclass of: aetiopathogenetic role
IAO_0000115: A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
has related synonym: genotoxic agent
has related synonym: genotoxic agents
has related synonym: genotoxins

carcinogenic agent
type: Class
subclass of: aetiopathogenetic role
IAO_0000115: A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
has related synonym: agente carcinogeno
has related synonym: cancerigene
has related synonym: cancerogene
has related synonym: carcinogen
has related synonym: carcinogene
has related synonym: carcinogenic agents
has related synonym: carcinogeno
has related synonym: carcinogens

allergen
type: Class
subclass of: aetiopathogenetic role
IAO_0000115: A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
has related synonym: alergeno
has related synonym: allergene
has related synonym: allergenic agent

role
type: Class
subclass of: role
IAO_0000115: A role is particular behaviour which a material entity may exhibit.

neurotoxin
type: Class
subclass of: aetiopathogenetic role
subclass of: poison
IAO_0000115: A poison that interferes with the functions of the nervous system.
has related synonym: agente neurotoxico
has related synonym: nerve poison
has related synonym: nerve poisons
has related synonym: neurotoxic agent
has related synonym: neurotoxic agents
has related synonym: neurotoxicant
has related synonym: neurotoxins

hormone receptor modulator
type: Class
subclass of: receptor modulator
IAO_0000115: A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
has related synonym: hormone receptor modulators

chemical role
type: Class
subclass of: role
IAO_0000115: A role played by the molecular entity or part thereof within a chemical context.

nitrogen molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: food additive
subclass of: Restriction
  on property: has part
  some values from: nitrogen atom
has related synonym: Nitrogenous compounds
has related synonym: nitrogen compounds
has related synonym: nitrogen molecular entities

dipolar compound
type: Class
subclass of: organic molecule
IAO_0000115: An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case.
has related synonym: dipolar compounds

acenes
type: Class
subclass of: benzenoid aromatic compound
IAO_0000115: Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives.

tetracenes
type: Class
subclass of: acenes
IAO_0000115: Compounds containing a tetracene skeleton.
has related synonym: naphthacenes

organodiyl group
type: Class
subclass of: organic divalent group
IAO_0000115: Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
has related synonym: organodiyl groups

organic divalent group
type: Class
subclass of: organic group

organic univalent group
type: Class
subclass of: organic group

organic polycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: organic cyclic compound
has related synonym: organic polycyclic compounds

biochemical role
type: Class
subclass of: biological role
IAO_0000115: A biological role played by the molecular entity or part thereof within a biochemical context.

aetiopathogenetic role
type: Class
subclass of: biological role
IAO_0000115: A role played by the molecular entity or part thereof which causes the development of a pathological process.
has related synonym: etiopathogenetic agent
has related synonym: etiopathogenetic role

pharmacological role
type: Class
subclass of: biological role
IAO_0000115: A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.

physiological role
type: Class
subclass of: biological role

ligand
type: Class
subclass of: chemical role
IAO_0000115: Any molecule or ion capable of binding to a central metal atom to form coordination complexes.
has related synonym: ligands

pharmaceutical
type: Class
subclass of: application
IAO_0000115: Any substance introduced into a living organism with therapeutic or diagnostic purpose.
has related synonym: farmaco
has related synonym: medicament
has related synonym: pharmaceuticals

oxyketone
type: Class
subclass of: ketone
IAO_0000115: A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group.
has related synonym: oxyketones

alpha-oxyketone
type: Class
subclass of: oxyketone
IAO_0000115: An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom.
has related synonym: alpha-oxyketones

inorganic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: inorganic molecular entity
has related synonym: inorganic hydroxides

heterocyclic compound
type: Class
subclass of: cyclic compound
IAO_0000115: A cyclic compound having as ring members atoms of at least two different elements.
has exact synonym: Heterocyclic compound
has related synonym: compuesto heterociclico
has related synonym: compuestos heterociclicos
has related synonym: heterocycle
has related synonym: heterocyclic compounds

carbon monoxide(1+)
type: Class
subclass of: organic cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbon monoxide
IAO_0000115: Conjugate acid of carbon monoxide arising from protonation of the carbon; major species at pH 7.3.
has exact synonym: methylidyneoxonium
has related synonym: CO(1+)
has related synonym: methylidyneoxidanium

biomarker
type: Class
subclass of: indicator
IAO_0000115: A substance used as an indicator of a biological state.
has related synonym: biological marker

chemical substance
type: Class
subclass of: chemical entity
IAO_0000115: A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.
has related synonym: Chemische Substanz

monovalent inorganic cation
type: Class
subclass of: inorganic cation
IAO_0000115: An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.
has related synonym: a monovalent cation

signalling molecule
type: Class
subclass of: molecular messenger
IAO_0000115: A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
has related synonym: signal molecule
has related synonym: signal molecules
has related synonym: signaling molecule
has related synonym: signaling molecules
has related synonym: signalling molecules

oxidising agent
type: Class
subclass of: chemical role
IAO_0000115: A substance that removes electrons from another reactant in a redox reaction.
has related synonym: oxidant
has related synonym: oxidants
has related synonym: oxidiser
has related synonym: oxidisers
has related synonym: oxidising agents
has related synonym: oxidizer
has related synonym: oxidizers
has related synonym: oxidizing agent
has related synonym: oxidizing agents

food additive
type: Class
subclass of: application
subclass of: food component
IAO_0000115: Any substance which is added to food to preserve or enhance its flavour and/or appearance.
has related synonym: food additives

food acidity regulator
type: Class
subclass of: food additive
IAO_0000115: A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
has related synonym: acidity regulator
has related synonym: acidity regulators
has related synonym: food acidity regulators
has related synonym: pH control agent
has related synonym: pH control agents

one-carbon compound
type: Class
subclass of: organic molecular entity
IAO_0000115: An organic molecular entity containing a single carbon atom (C1).
has related synonym: one-carbon compounds

organic acid
type: Class
subclass of: organic molecular entity
IAO_0000115: Any organic molecular entity that is acidic and contains carbon in covalent linkage.
has related synonym: organic acids

poison
type: Class
subclass of: biological role
IAO_0000115: Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
has related synonym: poisonous agent
has related synonym: poisonous agents
has related synonym: poisonous substance
has related synonym: poisonous substances
has related synonym: poisons
has related synonym: toxic agent
has related synonym: toxic agents
has related synonym: toxic substance
has related synonym: toxic substances

food preservative
type: Class
subclass of: food additive
IAO_0000115: Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
has related synonym: food preservatives

antimicrobial food preservative
type: Class
subclass of: antimicrobial agent
subclass of: food preservative
IAO_0000115: A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
has related synonym: antimicrobial food preservatives
has related synonym: antimicrobial preservative
has related synonym: antimicrobial preservatives

anti-inflammatory agent
type: Class
subclass of: application
IAO_0000115: Any compound that has anti-inflammatory effects.
has related synonym: anti-inflammatory agents
has related synonym: antiinflammatory agent
has related synonym: antiinflammatory agents

tetracycline(1-)
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: tetracycline
subclass of: Restriction
  on property: is conjugate base of
  some values from: tetracycline zwitterion
IAO_0000115: An organic anion that is the conjugate base of tetracycline obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group.
has exact synonym: (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,7,11-trihydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracene-2,5-diolate
has related synonym: tetracycline anion

organic molecule
type: Class
subclass of: molecule
subclass of: organic molecular entity
IAO_0000115: Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
has related synonym: organic compound
has related synonym: organic compounds
has related synonym: organic molecules

astringent
type: Class
subclass of: drug
IAO_0000115: A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.
has related synonym: adstringent
has related synonym: adstringents
has related synonym: astringents

eukaryotic metabolite
type: Class
subclass of: metabolite
IAO_0000115: Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
has related synonym: eukaryotic metabolites

animal metabolite
type: Class
subclass of: eukaryotic metabolite
IAO_0000115: Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
has related synonym: animal metabolites

mammalian metabolite
type: Class
subclass of: animal metabolite
IAO_0000115: Any animal metabolite produced during a metabolic reaction in mammals.
has related synonym: mammalian metabolites

mouse metabolite
type: Class
subclass of: mammalian metabolite
IAO_0000115: Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
has related synonym: Mus musculus metabolite
has related synonym: Mus musculus metabolites
has related synonym: mouse metabolites

Saccharomyces cerevisiae metabolite
type: Class
subclass of: fungal metabolite
IAO_0000115: Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
has related synonym: S. cerevisiae metabolite
has related synonym: S. cerevisiae metabolites
has related synonym: S. cerevisiae secondary metabolite
has related synonym: S. cerevisiae secondary metabolites
has related synonym: Saccharomyces cerevisiae metabolites
has related synonym: Saccharomyces cerevisiae secondary metabolites
has related synonym: baker's yeast metabolite
has related synonym: baker's yeast metabolites
has related synonym: baker's yeast secondary metabolite
has related synonym: baker's yeast secondary metabolites

prokaryotic metabolite
type: Class
subclass of: metabolite
IAO_0000115: Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
has related synonym: prokaryotic metabolites

greenhouse gas
type: Class
subclass of: chemical role
IAO_0000115: A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.
has related synonym: greenhouse gases

propellant
type: Class
subclass of: application
IAO_0000115: A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans.
has related synonym: propellants

EC 1.* (oxidoreductase) inhibitor
type: Class
subclass of: enzyme inhibitor
IAO_0000115: An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
has related synonym: EC 1.* (oxidoreductase) inhibitors
has related synonym: EC 1.* inhibitor
has related synonym: EC 1.* inhibitors
has related synonym: oxidoreductase (EC 1.*) inhibitor
has related synonym: oxidoreductase (EC 1.*) inhibitors
has related synonym: oxidoreductase inhibitor
has related synonym: oxidoreductase inhibitors

EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
IAO_0000115: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*).
has related synonym: EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor
has related synonym: EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors
has related synonym: EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors
has related synonym: EC 1.9.* inhibitor
has related synonym: EC 1.9.* inhibitors
has related synonym: oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor
has related synonym: oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors

EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor
IAO_0000115: An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*).
has related synonym: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
has related synonym: EC 1.14.* inhibitor
has related synonym: EC 1.14.* inhibitors
has related synonym: inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has related synonym: inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has related synonym: inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has related synonym: inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
has related synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor
has related synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors
has related synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor
has related synonym: oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors

EC 3.* (hydrolase) inhibitor
type: Class
subclass of: enzyme inhibitor
IAO_0000115: Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
has related synonym: EC 3.* (hydrolase) inhibitors
has related synonym: EC 3.* inhibitor
has related synonym: EC 3.* inhibitors
has related synonym: EC 3.*.*.* inhibitor
has related synonym: EC 3.*.*.* inhibitors
has related synonym: hydrolase (EC 3.*) inhibitor
has related synonym: hydrolase (EC 3.*) inhibitors
has related synonym: hydrolase inhibitor
has related synonym: hydrolase inhibitors

EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
IAO_0000115: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
has related synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
has related synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
has related synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
has related synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
has related synonym: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
has related synonym: EC 3.5.* inhibitor
has related synonym: EC 3.5.* inhibitors

EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
IAO_0000115: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
has related synonym: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
has related synonym: EC 3.5.1.* inhibitor
has related synonym: EC 3.5.1.* inhibitors
has related synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
has related synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors

EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
IAO_0000115: An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
has related synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
has related synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
has related synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
has related synonym: EC 1.14.14.* inhibitor
has related synonym: EC 1.14.14.* inhibitors
has related synonym: oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor
has related synonym: oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors

EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
type: Class
subclass of: EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
IAO_0000115: An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*).
has related synonym: EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors
has related synonym: EC 1.9.3.* inhibitor
has related synonym: EC 1.9.3.* inhibitors
has related synonym: oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor
has related synonym: oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors

EC 1.14.14.1 (unspecific monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
IAO_0000115: An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1).
has related synonym: EC 1.14.14.1 (unspecific monooxygenase) inhibitors
has related synonym: EC 1.14.14.1 inhibitor
has related synonym: EC 1.14.14.1 inhibitors
has related synonym: aryl hydrocarbon hydroxylase inhibitor
has related synonym: aryl hydrocarbon hydroxylase inhibitors
has related synonym: aryl-4-monooxygenase inhibitor
has related synonym: aryl-4-monooxygenase inhibitors
has related synonym: flavoprotein monooxygenase inhibitor
has related synonym: flavoprotein monooxygenase inhibitors
has related synonym: flavoprotein-linked monooxygenase inhibitor
has related synonym: flavoprotein-linked monooxygenase inhibitors
has related synonym: microsomal P-450 inhibitor
has related synonym: microsomal P-450 inhibitors
has related synonym: microsomal monooxygenase inhibitor
has related synonym: microsomal monooxygenase inhibitors
has related synonym: substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor
has related synonym: substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors
has related synonym: unspecific monooxygenase (EC 1.14.14.1) inhibitor
has related synonym: unspecific monooxygenase (EC 1.14.14.1) inhibitors
has related synonym: unspecific monooxygenase inhibitor
has related synonym: unspecific monooxygenase inhibitors
has related synonym: xenobiotic monooxygenase inhibitor
has related synonym: xenobiotic monooxygenase inhibitors

pathway inhibitor
type: Class
subclass of: enzyme inhibitor
IAO_0000115: An enzyme inhibitor that interferes with one or more steps in a metabolic pathway.
has related synonym: metabolic pathway inhibitor
has related synonym: metabolic pathway inhibitors
has related synonym: pathway inhibitors

fungal metabolite
type: Class
subclass of: eukaryotic metabolite
IAO_0000115: Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
has related synonym: fungal metabolites

bacterial metabolite
type: Class
subclass of: prokaryotic metabolite
IAO_0000115: Any prokaryotic metabolite produced during a metabolic reaction in bacteria.

Escherichia coli metabolite
type: Class
subclass of: bacterial metabolite
IAO_0000115: Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
has related synonym: E.coli metabolite
has related synonym: E.coli metabolites
has related synonym: Escherichia coli metabolites

human metabolite
type: Class
subclass of: mammalian metabolite
IAO_0000115: Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
has related synonym: H. sapiens metabolite
has related synonym: H. sapiens metabolites
has related synonym: Homo sapiens metabolite
has related synonym: Homo sapiens metabolites

tetracycline zwitterion
type: Class
subclass of: a tetracycline zwittterion
subclass of: zwitterion
subclass of: Restriction
  on property: has role
  some values from: antiprotozoal drug
subclass of: Restriction
  on property: has role
  some values from: antibacterial drug
subclass of: Restriction
  on property: has role
  some values from: protein synthesis inhibitor
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tetracycline(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: tetracycline
IAO_0000115: A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).
has exact synonym: (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,5,7,11-tetrahydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate
has related synonym: tetracycline

EC 3.5.1.4 (amidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
IAO_0000115: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
has related synonym: EC 3.5.1.4 (amidase) inhibitors
has related synonym: EC 3.5.1.4 inhibitor
has related synonym: EC 3.5.1.4 inhibitors
has related synonym: N-acetylaminohydrolase inhibitor
has related synonym: N-acetylaminohydrolase inhibitors
has related synonym: acylamidase inhibitor
has related synonym: acylamidase inhibitors
has related synonym: acylamide amidohydrolase inhibitor
has related synonym: acylamide amidohydrolase inhibitors
has related synonym: amidase (EC 3.5.1.4) inhibitor
has related synonym: amidase (EC 3.5.1.4) inhibitors
has related synonym: amidase inhibitor
has related synonym: amidase inhibitors
has related synonym: amidohydrolase inhibitor
has related synonym: amidohydrolase inhibitors
has related synonym: deaminase inhibitor
has related synonym: deaminase inhibitors
has related synonym: fatty acylamidase inhibitor
has related synonym: fatty acylamidase inhibitors

food packaging gas
type: Class
subclass of: food additive
IAO_0000115: A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
has related synonym: food packaging gases

food propellant
type: Class
subclass of: food additive
subclass of: propellant
IAO_0000115: A propellant that is used to expel foods from an aerosol container.
has related synonym: food propellants

food component
type: Class
subclass of: physiological role
IAO_0000115: A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
IAO_0000115: Any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
has related synonym: dietary component
has related synonym: dietary components
has related synonym: food components

environmental contaminant
type: Class
subclass of: chemical role
IAO_0000115: Any minor or unwanted substance introduced into the environment that can have undesired effects.
has related synonym: environmental contaminants

refrigerant
type: Class
subclass of: application
IAO_0000115: A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
has related synonym: refrigerants

flame retardant
type: Class
subclass of: application
IAO_0000115: Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire.
has related synonym: flame retardants

monovalent inorganic anion
type: Class
subclass of: inorganic anion
IAO_0000115: Any inorganic anion with a valency of one.
has related synonym: monovalent inorganic anions

crustacean metabolite
type: Class
subclass of: animal metabolite
IAO_0000115: An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
has related synonym: crustacean metabolites

Daphnia magna metabolite
type: Class
subclass of: Daphnia metabolite
IAO_0000115: A Daphnia metabolite produced by the species Daphnia magna.
has related synonym: Daphnia magna metabolites

Daphnia metabolite
type: Class
subclass of: crustacean metabolite
IAO_0000115: A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
has related synonym: Daphnia metabolites

haloacetate(1-)
type: Class
subclass of: monocarboxylic acid anion
subclass of: Restriction
  on property: has functional parent
  some values from: acetate
subclass of: Restriction
  on property: is conjugate base of
  some values from: haloacetic acid
IAO_0000115: A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of a haloacetic acid.
has related synonym: a haloacetate
has related synonym: haloacetate (1-)

receptor modulator
type: Class
subclass of: drug
IAO_0000115: A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.
has related synonym: receptor modulators

exposure to radiation
type: Class
subclass of: exposure to environmental process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to radiation.
has exact synonym: radiation exposure

exposure to electromagnetic radiation
type: Class
subclass of: exposure to radiation
IAO_0000115: A exposure event involving the interaction of an exposure receptor to electromagnetic radiation.
has exact synonym: electromagnetic radiation exposure

exposure to ultraviolet radiation
type: Class
subclass of: exposure to electromagnetic radiation
IAO_0000115: A exposure event involving the interaction of an exposure receptor to ultraviolet radiation.
has exact synonym: ultraviolet radiation exposure

exposure to visible light radiation
type: Class
subclass of: exposure to electromagnetic radiation
IAO_0000115: A exposure event involving the interaction of an exposure receptor to visible spectrum radiation.
has exact synonym: visible spectrum radiation exposure

exposure to environmental material
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to environmental material.
has exact synonym: environmental material exposure

exposure to organic compound
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: organic molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: organic molecular entity
IAO_0000115: An exposure to organic molecular entity.
has exact synonym: exposure to organic molecular entity

exposure to organic cyclic compound
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: organic cyclic compound
subclass of: exposure to organic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: organic cyclic compound
IAO_0000115: An exposure to organic cyclic compound.
has exact synonym: exposure to organic cyclic compound

exposure to corticosteroid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: corticosteroid
subclass of: exposure to steroid
subclass of: Restriction
  on property: has exposure stimulus
  some values from: corticosteroid
IAO_0000115: An exposure to corticosteroid.
has exact synonym: exposure to corticosteroid

exposure to lipid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: lipid
subclass of: exposure to organic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: lipid
IAO_0000115: An exposure to lipid.
has exact synonym: exposure to lipid

exposure to carbon monoxide
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: carbon monoxide
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: exposure to gas molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: carbon monoxide
IAO_0000115: An exposure to carbon monoxide.
has exact synonym: exposure to carbon monoxide

exposure to chemical
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: chemical entity
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: chemical entity
IAO_0000115: An exposure to chemical entity.
has exact synonym: exposure to chemical entity

exposure to steroid hormone
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: steroid hormone
subclass of: exposure to steroid
subclass of: Restriction
  on property: has exposure stimulus
  some values from: steroid hormone
IAO_0000115: An exposure to steroid hormone.
has exact synonym: exposure to steroid hormone

exposure to glucocorticoid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: glucocorticoid
subclass of: exposure to corticosteroid
subclass of: exposure to steroid hormone
subclass of: Restriction
  on property: has exposure stimulus
  some values from: glucocorticoid
IAO_0000115: An exposure to glucocorticoid.
has exact synonym: exposure to glucocorticoid

exposure to oxygen molecular entity
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: oxygen molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: oxygen molecular entity
IAO_0000115: An exposure to oxygen molecular entity.
has exact synonym: exposure to oxygen molecular entity

exposure to formaldehyde
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: formaldehyde
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: formaldehyde
IAO_0000115: An exposure to formaldehyde.
has exact synonym: exposure to formaldehyde

exposure to transition element
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: transition element molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: transition element molecular entity
IAO_0000115: An exposure to transition element molecular entity.
has exact synonym: exposure to transition element molecular entity

exposure to chemical with biological effect
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: biological role
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: biological role
IAO_0000115: An exposure to biological role.
has exact synonym: exposure to biological role

exposure to chemical with application
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: application
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: application
IAO_0000115: An exposure to application.
has exact synonym: exposure to application

exposure to chemical with chemical role
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: chemical role
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: chemical role
IAO_0000115: An exposure to chemical role.
has exact synonym: exposure to chemical role

exposure to alkylating agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: alkylating agent
subclass of: exposure to mutagen
subclass of: Restriction
  on property: has exposure stimulus
  some values from: alkylating agent
IAO_0000115: An exposure to alkylating agent.
has exact synonym: exposure to alkylating agent

exposure to drug
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: drug
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: drug
IAO_0000115: An exposure to drug.
has exact synonym: exposure to drug

exposure to herbicide
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: herbicide
subclass of: exposure to pesticide
subclass of: Restriction
  on property: has exposure stimulus
  some values from: herbicide
IAO_0000115: An exposure to herbicide.
has exact synonym: exposure to herbicide

exposure to hormone
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: hormone
subclass of: exposure to molecular messenger
subclass of: exposure to agonist
subclass of: Restriction
  on property: has exposure stimulus
  some values from: hormone
IAO_0000115: An exposure to hormone.
has exact synonym: exposure to hormone

exposure to mitochondrial respiratory-chain inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: mitochondrial respiratory-chain inhibitor
subclass of: exposure to inhibitor
subclass of: Restriction
  on property: has exposure stimulus
  some values from: mitochondrial respiratory-chain inhibitor
IAO_0000115: An exposure to mitochondrial respiratory-chain inhibitor.
has exact synonym: exposure to mitochondrial respiratory-chain inhibitor

exposure to mutagen
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: mutagen
subclass of: exposure to genotoxin
subclass of: Restriction
  on property: has exposure stimulus
  some values from: mutagen
IAO_0000115: An exposure to mutagen.
has exact synonym: exposure to mutagen

exposure to mycotoxin
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: mycotoxin
subclass of: exposure to toxin
subclass of: Restriction
  on property: has exposure stimulus
  some values from: mycotoxin
IAO_0000115: An exposure to mycotoxin.
has exact synonym: exposure to mycotoxin

exposure to neurotransmitter
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: neurotransmitter
subclass of: exposure to molecular messenger
subclass of: Restriction
  on property: has exposure stimulus
  some values from: neurotransmitter
IAO_0000115: An exposure to neurotransmitter.
has exact synonym: exposure to neurotransmitter

exposure to pesticide
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: pesticide
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: pesticide
IAO_0000115: An exposure to pesticide.
has exact synonym: exposure to pesticide

exposure to toxin
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: toxin
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: toxin
IAO_0000115: An exposure to toxin.
has exact synonym: exposure to toxin

exposure to molecular messenger
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: molecular messenger
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: molecular messenger
IAO_0000115: An exposure to molecular messenger.
has exact synonym: exposure to molecular messenger

exposure to antimicrobial agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antimicrobial agent
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antimicrobial agent
IAO_0000115: An exposure to antimicrobial agent.
has exact synonym: exposure to antimicrobial agent

exposure to inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: inhibitor
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: inhibitor
IAO_0000115: An exposure to inhibitor.
has exact synonym: exposure to inhibitor

exposure to vasodilator agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: vasodilator agent
subclass of: exposure to drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: vasodilator agent
IAO_0000115: An exposure to vasodilator agent.
has exact synonym: exposure to vasodilator agent

exposure to EC 1.9.3.1 (cytochrome c oxidase) inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: EC 1.9.3.1 (cytochrome c oxidase) inhibitor
subclass of: exposure to mitochondrial respiratory-chain inhibitor
subclass of: Restriction
  on property: has exposure stimulus
  some values from: EC 1.9.3.1 (cytochrome c oxidase) inhibitor
IAO_0000115: An exposure to EC 1.9.3.1 (cytochrome c oxidase) inhibitor.
has exact synonym: exposure to EC 1.9.3.1 (cytochrome c oxidase) inhibitor

exposure to Bronsted acid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Bronsted acid
subclass of: exposure to acids
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Bronsted acid
IAO_0000115: An exposure to Bronsted acid.
has exact synonym: exposure to Bronsted acid

exposure to disinfectant
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: disinfectant
subclass of: exposure to antimicrobial agent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: disinfectant
IAO_0000115: An exposure to disinfectant.
has exact synonym: exposure to disinfectant

exposure to agonist
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: agonist
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: agonist
IAO_0000115: An exposure to agonist.
has exact synonym: exposure to agonist

exposure to P450 inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: P450 inhibitor
subclass of: exposure to inhibitor
subclass of: Restriction
  on property: has exposure stimulus
  some values from: P450 inhibitor
IAO_0000115: An exposure to P450 inhibitor.
has exact synonym: exposure to P450 inhibitor

exposure to probe
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: probe
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: probe
IAO_0000115: An exposure to probe.
has exact synonym: exposure to probe

exposure to genotoxin
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: genotoxin
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: genotoxin
IAO_0000115: An exposure to genotoxin.
has exact synonym: exposure to genotoxin

exposure to carcinogenic agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: carcinogenic agent
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: carcinogenic agent
IAO_0000115: An exposure to carcinogenic agent.
has exact synonym: exposure to carcinogenic agent

exposure to allergen
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: allergen
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: allergen
IAO_0000115: An exposure to allergen.
has exact synonym: exposure to allergen

exposure to neurotoxin
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: neurotoxin
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: neurotoxin
IAO_0000115: An exposure to neurotoxin.
has exact synonym: exposure to neurotoxin

exposure to ligand
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: ligand
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: ligand
IAO_0000115: An exposure to ligand.
has exact synonym: exposure to ligand

exposure to biomarker
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: biomarker
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: biomarker
IAO_0000115: An exposure to biomarker.
has exact synonym: exposure to biomarker

exposure to signalling molecule
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: signalling molecule
subclass of: exposure to molecular messenger
subclass of: Restriction
  on property: has exposure stimulus
  some values from: signalling molecule
IAO_0000115: An exposure to signalling molecule.
has exact synonym: exposure to signalling molecule

exposure to EC 3.5.1.4 (amidase) inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: EC 3.5.1.4 (amidase) inhibitor
subclass of: exposure to inhibitor
subclass of: Restriction
  on property: has exposure stimulus
  some values from: EC 3.5.1.4 (amidase) inhibitor
IAO_0000115: An exposure to EC 3.5.1.4 (amidase) inhibitor.
has exact synonym: exposure to EC 3.5.1.4 (amidase) inhibitor

exposure to environmental contaminant
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: environmental contaminant
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: environmental contaminant
IAO_0000115: An exposure to environmental contaminant.
has exact synonym: exposure to environmental contaminant

exposure to temperature of environmental surroundings
type: Class
subclass of: exposure to environmental physical object quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to temperature of environmental material.
has exact synonym: temperature of environmental material exposure

exposure to temperature of air in surroundings
type: Class
subclass of: exposure to temperature of environmental surroundings
IAO_0000115: A exposure event involving the interaction of an exposure receptor to temperature of air.
has exact synonym: temperature of air exposure

exposure to decreased air temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of air.
has exact synonym: exposure to decreased amount in temperature of air

exposure to decreased temperature
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: decreased temperature
subclass of: exposure to qualitative environmental quality
subclass of: exposure to environmental physical object quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: decreased temperature
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased temperature.
has exact synonym: decreased temperature exposure

exposure to alcohol consumption
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Alcohol Consumption
subclass of: exposure to personal behavior
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Alcohol Consumption
IAO_0000115: An exposure event involving Alcohol Consumption
has exact synonym: Alcohol Consumption exposure

exposure to aflatoxin
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: aflatoxin
subclass of: exposure to organic cyclic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: aflatoxin
IAO_0000115: An exposure to aflatoxin.
has exact synonym: exposure to aflatoxin

exposure to organochlorine compound
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: organochlorine compound
subclass of: exposure to organic compound
subclass of: exposure to chlorine
subclass of: Restriction
  on property: has exposure stimulus
  some values from: organochlorine compound
IAO_0000115: An exposure to organochlorine compound.
has exact synonym: exposure to organochlorine compound

exposure to cadmium
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: cadmium molecular entity
subclass of: exposure to transition element
subclass of: Restriction
  on property: has exposure stimulus
  some values from: cadmium molecular entity
IAO_0000115: An exposure to cadmium molecular entity.
has exact synonym: exposure to cadmium molecular entity

exposure to mercury
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: mercury molecular entity
subclass of: exposure to transition element
subclass of: Restriction
  on property: has exposure stimulus
  some values from: mercury molecular entity
IAO_0000115: An exposure to mercury molecular entity.
has exact synonym: exposure to mercury molecular entity

exposure to occupation
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Occupation
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Occupation
IAO_0000115: An exposure event involving Occupation
has exact synonym: Occupation exposure

exposure to chloroacetic acid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: chloroacetic acid
subclass of: exposure to oxygen molecular entity
subclass of: exposure to organochlorine compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: chloroacetic acid
IAO_0000115: An exposure to chloroacetic acid.
has exact synonym: exposure to chloroacetic acid

exposure to steroid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: steroid
subclass of: exposure to organic cyclic compound
subclass of: exposure to lipid
subclass of: Restriction
  on property: has exposure stimulus
  some values from: steroid
IAO_0000115: An exposure to steroid.
has exact synonym: exposure to steroid

exposure to environmental quality
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: quality
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to quality.
has exact synonym: quality exposure

exposure to qualitative environmental quality
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: qualitative
subclass of: exposure to environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: qualitative
IAO_0000115: A exposure event involving the interaction of an exposure receptor to qualitative.
has exact synonym: qualitative exposure

exposure to environmental process quality
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: process quality
subclass of: exposure to environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: process quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to process quality.
has exact synonym: process quality exposure

exposure to environmental physical object quality
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: physical object quality
subclass of: exposure to environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: physical object quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to physical object quality.
has exact synonym: physical object quality exposure

exposure to environmental layer
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to layer.
has exact synonym: layer exposure

exposure to environmental disposition
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to environmental disposition.
has exact synonym: environmental disposition exposure

exposure to manufactured product
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to manufactured product.
has exact synonym: manufactured product exposure

exposure to environmental system
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to environmental system.
has exact synonym: environmental system exposure

exposure to environmental condition
type: Class
subclass of: exposure to environmental physical object quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to the condition of environmental condition.
has exact synonym: environmental condition exposure

exposure to high temperature environment
type: Class
subclass of: exposure to environmental system
IAO_0000115: A exposure event involving the interaction of an exposure receptor to high temperature environment.
has exact synonym: high temperature environment exposure

exposure to high pressure environment
type: Class
subclass of: exposure to environmental system
IAO_0000115: A exposure event involving the interaction of an exposure receptor to high pressure environment.
has exact synonym: high pressure environment exposure

exposure to organism
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: root
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: root
IAO_0000115: A history of exposure to root.
has exact synonym: root exposure

exposure to virus
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Viruses
subclass of: exposure to organism
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Viruses
IAO_0000115: A history of exposure to Viruses.
has exact synonym: Viruses exposure

exposure to humans
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Homo sapiens
subclass of: exposure to environmental material
subclass of: exposure to organism
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Homo sapiens
IAO_0000115: A history of exposure to Homo sapiens.
has exact synonym: Homo sapiens exposure

exposure to change
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Class
      intersection of: deviation (from_normal)
      intersection of: Restriction
        on property: inheres in
        some values from: quality
subclass of: exposure to qualitative environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Class
    intersection of: deviation (from_normal)
    intersection of: Restriction
      on property: inheres in
      some values from: quality
IAO_0000115: A exposure event involving the interaction of an exposure receptor to deviation (from_normal) of quality.
has exact synonym: exposure to deviation (from_normal) in quality

exposure to increased temperature
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: increased temperature
subclass of: exposure to qualitative environmental quality
subclass of: exposure to environmental physical object quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: increased temperature
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased temperature.
has exact synonym: increased temperature exposure

exposure to increased salt
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Class
      intersection of: increased amount
      intersection of: Restriction
        on property: inheres in
        some values from: salt
subclass of: exposure to qualitative environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Class
    intersection of: increased amount
    intersection of: Restriction
      on property: inheres in
      some values from: salt
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of salt.
has exact synonym: exposure to increased amount in salt

exposure to decreased salt
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Class
      intersection of: decreased amount
      intersection of: Restriction
        on property: inheres in
        some values from: salt
subclass of: exposure to qualitative environmental quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Class
    intersection of: decreased amount
    intersection of: Restriction
      on property: inheres in
      some values from: salt
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of salt.
has exact synonym: exposure to decreased amount in salt

exposure to increased air pressure
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of pressure of air.
has exact synonym: exposure to increased amount in pressure of air

exposure to increased pressure
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: increased pressure
subclass of: exposure to qualitative environmental quality
subclass of: exposure to environmental physical object quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: increased pressure
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased pressure.
has exact synonym: increased pressure exposure

exposure to decreased pressure
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: decreased pressure
subclass of: exposure to qualitative environmental quality
subclass of: exposure to environmental physical object quality
subclass of: Restriction
  on property: has exposure stimulus
  some values from: decreased pressure
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased pressure.
has exact synonym: decreased pressure exposure

exposure to freezing water
type: Class
subclass of: exposure to temperature of environmental surroundings
IAO_0000115: A exposure event involving the interaction of an exposure receptor to frozen of liquid water.
has exact synonym: exposure to frozen in liquid water

exposure to freezing air
type: Class
subclass of: exposure to temperature of air in surroundings
IAO_0000115: A exposure event involving the interaction of an exposure receptor to frozen of air.
has exact synonym: exposure to frozen in air

exposure to increased soil temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of temperature of soil.
has exact synonym: exposure to increased amount in temperature of soil

exposure to decreased soil temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of soil.
has exact synonym: exposure to decreased amount in temperature of soil

exposure to increased water temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of temperature of water.
has exact synonym: exposure to increased amount in temperature of water

exposure to decreased water temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of water.
has exact synonym: exposure to decreased amount in temperature of water

exposure to decreased water pressure
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of pressure of water.
has exact synonym: exposure to decreased amount in pressure of water

exposure to increased air temperature
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of temperature of air.
has exact synonym: exposure to increased amount in temperature of air

exposure to increased water pressure
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to increased amount of pressure of water.
has exact synonym: exposure to increased amount in pressure of water

exposure to decreased air pressure
type: Class
subclass of: exposure to change
IAO_0000115: A exposure event involving the interaction of an exposure receptor to decreased amount of pressure of air.
has exact synonym: exposure to decreased amount in pressure of air

exposure to geographic feature
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to geographic feature.
has exact synonym: geographic feature exposure

exposure to personal behavior
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: Personal Behavior
subclass of: exposure event
subclass of: exposure event or process
subclass of: Restriction
  on property: has exposure stimulus
  some values from: Personal Behavior
IAO_0000115: An exposure event involving Personal Behavior
has exact synonym: Personal Behavior exposure

exposure to clay
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to clay.
has exact synonym: clay exposure

exposure to soil
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to soil.
has exact synonym: soil exposure

exposure to rock
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to rock.
has exact synonym: rock exposure

exposure to sand
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to sand.
has exact synonym: sand exposure

exposure to stellar radiation
type: Class
subclass of: exposure to electromagnetic radiation
IAO_0000115: A exposure event involving the interaction of an exposure receptor to stellar radiation.
has exact synonym: stellar radiation exposure

exposure to gaseous environmental material
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to gaseous environmental material.
has exact synonym: gaseous environmental material exposure

exposure to water in environment
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to liquid water.
has exact synonym: liquid water exposure

exposure to air
type: Class
subclass of: exposure to gaseous environmental material
subclass of: exposure to mineral material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to air.
has exact synonym: air exposure

exposure to particulate matter
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to particulate matter.
has exact synonym: particulate matter exposure

exposure to organic material
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to organic material.
has exact synonym: organic material exposure

exposure to snow
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to snow.
has exact synonym: snow exposure

exposure to mineral material
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to mineral material.
has exact synonym: mineral material exposure

exposure to permafrost
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to permafrost.
has exact synonym: permafrost exposure

exposure to contaminated sediment
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to chemically enriched sediment.
has exact synonym: chemically enriched sediment exposure

exposure to aerosol
type: Class
subclass of: exposure to environmental material
IAO_0000115: A exposure event involving the interaction of an exposure receptor to aerosol.
has exact synonym: aerosol exposure

exposure to contaminated water
type: Class
subclass of: exposure to water in environment
IAO_0000115: A exposure event involving the interaction of an exposure receptor to contaminated water.
has exact synonym: contaminated water exposure

exposure to sea water
type: Class
subclass of: exposure to water in environment
IAO_0000115: A exposure event involving the interaction of an exposure receptor to sea water.
has exact synonym: sea water exposure

exposure to environmental process
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to environmental system process.
has exact synonym: environmental system process exposure

exposure to atmospheric process
type: Class
subclass of: exposure to environmental process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to atmospheric process.
has exact synonym: atmospheric process exposure

exposure to anthropogenic modulatory intervention process
type: Class
subclass of: exposure event
subclass of: exposure event or process
IAO_0000115: A exposure event involving the interaction of an exposure receptor to anthropogenic modulatory intervention process.
has exact synonym: anthropogenic modulatory intervention process exposure

exposure to hydrogen chloride
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: hydrogen chloride
subclass of: exposure to chlorine
subclass of: exposure to gas molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: hydrogen chloride
IAO_0000115: An exposure to hydrogen chloride.
has exact synonym: exposure to hydrogen chloride

exposure to acetic acid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: acetic acid
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: acetic acid
IAO_0000115: An exposure to acetic acid.
has exact synonym: exposure to acetic acid

exposure to alkali metal salt
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: alkali metal salt
subclass of: exposure to salt
subclass of: Restriction
  on property: has exposure stimulus
  some values from: alkali metal salt
IAO_0000115: An exposure to alkali metal salt.
has exact synonym: exposure to alkali metal salt

exposure to alcohol
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: alcohol
subclass of: exposure to environmental material
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: alcohol
IAO_0000115: An exposure to alcohol.
has exact synonym: exposure to alcohol

exposure to ketone
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: ketone
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: ketone
IAO_0000115: An exposure to ketone.
has exact synonym: exposure to ketone

exposure to carbon dioxide
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: carbon dioxide
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: exposure to gas molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: carbon dioxide
IAO_0000115: An exposure to carbon dioxide.
has exact synonym: exposure to carbon dioxide

exposure to chlorine
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: chlorine molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: chlorine molecular entity
IAO_0000115: An exposure to chlorine molecular entity.
has exact synonym: exposure to chlorine molecular entity

exposure to solvent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: solvent
subclass of: exposure to chemical with application
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: solvent
IAO_0000115: An exposure to solvent.
has exact synonym: exposure to solvent

exposure to water
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: water
subclass of: exposure to oxygen molecular entity
subclass of: exposure to inorganic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: water
IAO_0000115: An exposure to water.
has exact synonym: exposure to water

exposure to acetate
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: acetate
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: acetate
IAO_0000115: An exposure to acetate.
has exact synonym: exposure to acetate

exposure to inorganic compound
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: inorganic molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: inorganic molecular entity
IAO_0000115: An exposure to inorganic molecular entity.
has exact synonym: exposure to inorganic molecular entity

exposure to metal cation
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: metal cation
subclass of: exposure to inorganic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: metal cation
IAO_0000115: An exposure to metal cation.
has exact synonym: exposure to metal cation

obsolete chemical entity exposure
type: Class
IAO_0100001: exposure to chemical
deprecated: true

exposure to tetracycline
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: tetracycline
subclass of: exposure to alcohol
subclass of: exposure to ketone
subclass of: Restriction
  on property: has exposure stimulus
  some values from: tetracycline
IAO_0000115: An exposure to tetracycline.
has exact synonym: exposure to tetracycline

exposure to formic acid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: formic acid
subclass of: exposure to organic compound
subclass of: exposure to oxygen molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: formic acid
IAO_0000115: An exposure to formic acid.
has exact synonym: exposure to formic acid

exposure to nitrogen
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: nitrogen molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: nitrogen molecular entity
IAO_0000115: An exposure to nitrogen molecular entity.
has exact synonym: exposure to nitrogen molecular entity

exposure to salt
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: salt
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: salt
IAO_0000115: An exposure to salt.
has exact synonym: exposure to salt

exposure to polycyclic arene
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: polycyclic arene
subclass of: exposure to polycyclic hydrocarbon
subclass of: Restriction
  on property: has exposure stimulus
  some values from: polycyclic arene
IAO_0000115: An exposure to polycyclic arene.
has exact synonym: exposure to polycyclic arene

exposure to dioxygen
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: dioxygen
subclass of: exposure to oxygen molecular entity
subclass of: exposure to inorganic compound
subclass of: exposure to gas molecular entity
subclass of: Restriction
  on property: has exposure stimulus
  some values from: dioxygen
IAO_0000115: An exposure to dioxygen.
has exact synonym: exposure to dioxygen

obsolete exposure to chlorine atom
type: Class
IAO_0100001: exposure to chlorine
deprecated: true

exposure to primary alcohol
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: primary alcohol
subclass of: exposure to alcohol
subclass of: Restriction
  on property: has exposure stimulus
  some values from: primary alcohol
IAO_0000115: An exposure to primary alcohol.
has exact synonym: exposure to primary alcohol

exposure to sodium chloride
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: sodium chloride
subclass of: exposure to alkali metal salt
subclass of: exposure to chlorine
subclass of: exposure to inorganic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: sodium chloride
IAO_0000115: An exposure to sodium chloride.
has exact synonym: exposure to sodium chloride

exposure to inorganic acid
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: inorganic acid
subclass of: exposure to Bronsted acid
subclass of: Restriction
  on property: has exposure stimulus
  some values from: inorganic acid
IAO_0000115: An exposure to inorganic acid.
has exact synonym: exposure to inorganic acid

exposure to gas molecular entity
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: gas molecular entity
subclass of: exposure to chemical
subclass of: Restriction
  on property: has exposure stimulus
  some values from: gas molecular entity
IAO_0000115: An exposure to gas molecular entity.
has exact synonym: exposure to gas molecular entity

exposure to endocrine disruptor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: endocrine disruptor
subclass of: exposure to drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: endocrine disruptor
IAO_0000115: An exposure to endocrine disruptor.
has exact synonym: exposure to endocrine disruptor

exposure to electron donor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: electron donor
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: electron donor
IAO_0000115: An exposure to electron donor.
has exact synonym: exposure to electron donor

exposure to cofactor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: cofactor
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: cofactor
IAO_0000115: An exposure to cofactor.
has exact synonym: exposure to cofactor

exposure to micronutrient
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: micronutrient
subclass of: exposure to nutrient
subclass of: Restriction
  on property: has exposure stimulus
  some values from: micronutrient
IAO_0000115: An exposure to micronutrient.
has exact synonym: exposure to micronutrient

exposure to antibacterial agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antibacterial agent
subclass of: exposure to antimicrobial agent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antibacterial agent
IAO_0000115: An exposure to antibacterial agent.
has exact synonym: exposure to antibacterial agent

exposure to nutrient
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: nutrient
subclass of: exposure to food component
subclass of: Restriction
  on property: has exposure stimulus
  some values from: nutrient
IAO_0000115: An exposure to nutrient.
has exact synonym: exposure to nutrient

exposure to fuel
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: fuel
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: fuel
IAO_0000115: An exposure to fuel.
has exact synonym: exposure to fuel

exposure to reagent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: reagent
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: reagent
IAO_0000115: An exposure to reagent.
has exact synonym: exposure to reagent

exposure to macronutrient
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: macronutrient
subclass of: exposure to nutrient
subclass of: Restriction
  on property: has exposure stimulus
  some values from: macronutrient
IAO_0000115: An exposure to macronutrient.
has exact synonym: exposure to macronutrient

exposure to antiinfective agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antiinfective agent
subclass of: exposure to drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antiinfective agent
IAO_0000115: An exposure to antiinfective agent.
has exact synonym: exposure to antiinfective agent

exposure to antiparasitic agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antiparasitic agent
subclass of: exposure to antiinfective agent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antiparasitic agent
IAO_0000115: An exposure to antiparasitic agent.
has exact synonym: exposure to antiparasitic agent

exposure to anti-inflammatory drug
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: anti-inflammatory drug
subclass of: exposure to drug
subclass of: exposure to anti-inflammatory agent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: anti-inflammatory drug
IAO_0000115: An exposure to anti-inflammatory drug.
has exact synonym: exposure to anti-inflammatory drug

exposure to antiprotozoal drug
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antiprotozoal drug
subclass of: exposure to antiparasitic agent
subclass of: exposure to antimicrobial drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antiprotozoal drug
IAO_0000115: An exposure to antiprotozoal drug.
has exact synonym: exposure to antiprotozoal drug

exposure to antimicrobial drug
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antimicrobial drug
subclass of: exposure to antimicrobial agent
subclass of: exposure to antiinfective agent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antimicrobial drug
IAO_0000115: An exposure to antimicrobial drug.
has exact synonym: exposure to antimicrobial drug

exposure to antibacterial drug
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antibacterial drug
subclass of: exposure to antibacterial agent
subclass of: exposure to antimicrobial drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antibacterial drug
IAO_0000115: An exposure to antibacterial drug.
has exact synonym: exposure to antibacterial drug

exposure to anaesthetic
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: anaesthetic
subclass of: exposure to drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: anaesthetic
IAO_0000115: An exposure to anaesthetic.
has exact synonym: exposure to anaesthetic

exposure to protein synthesis inhibitor
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: protein synthesis inhibitor
subclass of: exposure to inhibitor
subclass of: Restriction
  on property: has exposure stimulus
  some values from: protein synthesis inhibitor
IAO_0000115: An exposure to protein synthesis inhibitor.
has exact synonym: exposure to protein synthesis inhibitor

exposure to polar solvent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: polar solvent
subclass of: exposure to solvent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: polar solvent
IAO_0000115: An exposure to polar solvent.
has exact synonym: exposure to polar solvent

exposure to protic solvent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: protic solvent
subclass of: exposure to Bronsted acid
subclass of: exposure to polar solvent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: protic solvent
IAO_0000115: An exposure to protic solvent.
has exact synonym: exposure to protic solvent

exposure to amphiprotic solvent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: amphiprotic solvent
subclass of: exposure to protic solvent
subclass of: Restriction
  on property: has exposure stimulus
  some values from: amphiprotic solvent
IAO_0000115: An exposure to amphiprotic solvent.
has exact synonym: exposure to amphiprotic solvent

exposure to antagonist
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antagonist
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antagonist
IAO_0000115: An exposure to antagonist.
has exact synonym: exposure to antagonist

exposure to oxidising agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: oxidising agent
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: oxidising agent
IAO_0000115: An exposure to oxidising agent.
has exact synonym: exposure to oxidising agent

exposure to food additive
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food additive
subclass of: exposure to chemical with application
subclass of: exposure to food component
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food additive
IAO_0000115: An exposure to food additive.
has exact synonym: exposure to food additive

exposure to food acidity regulator
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food acidity regulator
subclass of: exposure to food additive
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food acidity regulator
IAO_0000115: An exposure to food acidity regulator.
has exact synonym: exposure to food acidity regulator

exposure to antimicrobial food preservative
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: antimicrobial food preservative
subclass of: exposure to antimicrobial agent
subclass of: exposure to food preservative
subclass of: Restriction
  on property: has exposure stimulus
  some values from: antimicrobial food preservative
IAO_0000115: An exposure to antimicrobial food preservative.
has exact synonym: exposure to antimicrobial food preservative

exposure to anti-inflammatory agent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: anti-inflammatory agent
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: anti-inflammatory agent
IAO_0000115: An exposure to anti-inflammatory agent.
has exact synonym: exposure to anti-inflammatory agent

exposure to astringent
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: astringent
subclass of: exposure to drug
subclass of: Restriction
  on property: has exposure stimulus
  some values from: astringent
IAO_0000115: An exposure to astringent.
has exact synonym: exposure to astringent

exposure to greenhouse gas
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: greenhouse gas
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: greenhouse gas
IAO_0000115: An exposure to greenhouse gas.
has exact synonym: exposure to greenhouse gas

exposure to food packaging gas
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food packaging gas
subclass of: exposure to food additive
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food packaging gas
IAO_0000115: An exposure to food packaging gas.
has exact synonym: exposure to food packaging gas

exposure to food propellant
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food propellant
subclass of: exposure to food additive
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food propellant
IAO_0000115: An exposure to food propellant.
has exact synonym: exposure to food propellant

exposure to food component
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food component
subclass of: exposure to chemical with biological effect
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food component
IAO_0000115: An exposure to food component.
has exact synonym: exposure to food component

exposure to refrigerant
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: refrigerant
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: refrigerant
IAO_0000115: An exposure to refrigerant.
has exact synonym: exposure to refrigerant

exposure to food preservative
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: food preservative
subclass of: exposure to food additive
subclass of: Restriction
  on property: has exposure stimulus
  some values from: food preservative
IAO_0000115: An exposure to food preservative.
has exact synonym: exposure to food preservative

exposure to flame retardant
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: flame retardant
subclass of: exposure to chemical with application
subclass of: Restriction
  on property: has exposure stimulus
  some values from: flame retardant
IAO_0000115: An exposure to flame retardant.
has exact synonym: exposure to flame retardant

exposure to acids
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: acid
subclass of: exposure to chemical with chemical role
subclass of: Restriction
  on property: has exposure stimulus
  some values from: acid
IAO_0000115: An exposure to acid.
has exact synonym: exposure to acid

exposure to polycyclic hydrocarbon
type: Class
equivalent class: Class
  intersection of: exposure event
  intersection of: Restriction
    on property: has exposure stimulus
    some values from: polycyclic hydrocarbon
subclass of: exposure to organic cyclic compound
subclass of: Restriction
  on property: has exposure stimulus
  some values from: polycyclic hydrocarbon
IAO_0000115: An exposure to polycyclic hydrocarbon.
has exact synonym: exposure to polycyclic hydrocarbon

exposure stressor
type: Class
subclass of: Restriction
  on property: interacts_with
  some values from: exposure_receptor
subclass of: Restriction
  on property: interacts_with_an_exposure_receptor_via
  some values from: exposure event
IAO_0000115: An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure_receptor during an exposure event.

exposure_receptor
type: Class
subclass of: Restriction
  on property: interacts_with
  some values from: exposure stressor
IAO_0000115: An entity (e.g., a human, human population, or a human organ) that interacts with an exposure stressor during an exposure event.

exposure event
type: Class
subclass of: process
subclass of: Restriction
  on property: has part
  some values from: exposure stressor
subclass of: Restriction
  on property: has part
  some values from: exposure_receptor
subclass of: Restriction
  on property: interacts_with_an_exposure_receptor_via
  some values from: exposure stressor
subclass of: Restriction
  on property: interacts_with_an_exposure stressor_via
  some values from: exposure_receptor
IAO_0000115: An interaction between an exposure stressor and an exposure_receptor.

food product
type: Class
subclass of: food material
IAO_0000115: Food material for humans and animals which is processed with the intention that it be consumable as a whole or added to other food products.

vertebrate animal food product
type: Class
equivalent class: Class
  intersection of: food product by organism
  intersection of: Restriction
    on property: derives from
    some values from: vertebrate animal
subclass of: food product by organism
subclass of: Restriction
  on property: derives from
  some values from: vertebrate animal
IAO_0000115: A food product which is derived from or produced by an animal that has a vertibrae.

fermented beverage
type: Class
equivalent class: Class
  intersection of: food (fermented)
  intersection of: beverage food product
subclass of: food (fermented)
subclass of: beverage food product
has exact synonym: alcoholic beverage

invertebrate animal food product
type: Class
equivalent class: Class
  intersection of: food product by organism
  intersection of: Restriction
    on property: derives from
    some values from: invertebrate animal
subclass of: food product by organism
subclass of: Restriction
  on property: derives from
  some values from: invertebrate animal

food (fermented)
type: Class
subclass of: multi-component food product
subclass of: food product by process
subclass of: Restriction
  on property: output of
  some values from: food fermentation

food fermentation
type: Class
subclass of: microbial/enzymatic modification process
subclass of: food preservation process
subclass of: Restriction
  on property: has output
  some values from: food (fermented)
IAO_0000115: A fermentation process in which either carbohydrates, proteins or fats are modified through microbial, enzymatic and/or other biological process.

alcoholic beverage
type: Class
subclass of: fermented beverage
IAO_0000115: An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar.

food product by meal type
type: Class
subclass of: food product
IAO_0000115: A meal type is the name of an eating occasion that may have location, food type, or other customary contextual features. (Damion's 1st draft definition)

food product by organism
type: Class
subclass of: food product
subclass of: Restriction
  on property: derives from
  some values from: food product organismal source
IAO_0000115: A food product consisting of food material derived primarily from a single organism.

food material
type: Class
subclass of: fiat object
subclass of: Restriction
  on property: has role
  some values from: food
IAO_0000115: Any substance that can be consumed by an organism to satisfy nutritional or other health needs, or to provide a social or organoleptic food experience
has exact synonym: food
has exact synonym: foodstuff
has exact synonym: nourishment
has exact synonym: sustenance

food transformation process
type: Class
subclass of: process
subclass of: Restriction
  on property: has output
  some values from: food material
IAO_0000115: A process involving the physical transformation of a food source or food product into some derived organic material or food product

invertebrate animal
type: Class
subclass of: animal
IAO_0000115: Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord. This includes all animals apart from the subphylum Vertebrata.
has broad synonym: animal

multi-component food product
type: Class
subclass of: food product
subclass of: Restriction
  on property: derives from
  some values from: food product by organism
subclass of: Restriction
  on property: member of
  some values from: multicomponent meal (us cfr)
IAO_0000115: A food product consisting of food material derived from ingredients sourced from multiple organisms.

food product by process
type: Class
subclass of: food product
IAO_0000115: A food product organized by the process which it results from.

animal
type: Class
subclass of: food product organismal source
IAO_0000115: A multicellular eukaryotic heterotrophic organism within the kingdom Animalia.

vegetarian food product
type: Class
equivalent class: Class
  intersection of: food product
  intersection of: Class
    complement of: Restriction
      on property: derives from
      some values from: Class
        union of: invertebrate animal
        union of: vertebrate animal
subclass of: food product by organism
IAO_0000115: A food product not including meat and animal tissue products (such as gelatin or animal-derived rennet).
has exact synonym: vegetarian food

beverage food product
type: Class
subclass of: food product by meal type
subclass of: Restriction
  on property: member of
  some values from: beverage (us cfr)
IAO_0000115: A liquid prepared for consumption, or a product that can be combined with water or milk to make one.

multicomponent meal (us cfr)
type: Class
subclass of: prepared food product (us cfr)
IAO_0000115: A multiple-component food product typically containing a protein source, a vegetable, and a potato, rice or cereal-based component packaged to be served after heating, either as separate items or courses or mixed as recipe components; see 21 CFR 102.26, 102.28 and 104.47 for nutritional quality guidelines.

prepared food product (us cfr)
type: Class
subclass of: U.S. code of federal regulations, title 21 food product type
IAO_0000115: Food product that is 1) ready or nearly ready for consumption; 2) usually a composite of several foods or ingredients that often belong to distinct product types; 3) usually formulated, mixed and partially or fully cooked. Prepared foods often undergo several of the processes listed in *F. EXTENT OF HEAT TREATMENT* and *H. TREATMENT APPLIED*; these factors should be carefully considered in indexing. The classification of prepared food products emphasizes consumption characteristics. [FDA CFSAN 1995]

beverage (us cfr)
type: Class
subclass of: U.S. code of federal regulations, title 21 food product type
subclass of: Class
  intersection of: Restriction
    on property: has member
    some values from: beverage food product
  intersection of: Restriction
    on property: has member
    all values from: beverage food product
IAO_0000115: Alcoholic or nonalcoholic beverage; excludes milk and milk-based beverages, fruit juices and fruit juice drinks, and vegetable juices. [FDA CFSAN 1995]

USA agency food product type
type: Class
subclass of: agency food product type
IAO_0000115: Food group having common consumption, functional or manufacturing characteristics, e.g. *FRUIT OR VEGETABLE PRODUCT*, *DAIRY PRODUCT*, *CONFECTIONARY*, *PREPARED FOOD PRODUCT*, etc. [FDA CFSAN 1995]

agency food product type
type: Class
subclass of: food material
IAO_0000115: An agency food product type is a class of food product defined by an agency or consortium.

U.S. code of federal regulations, title 21 food product type
type: Class
subclass of: USA agency food product type
IAO_0000115: Food and Drugs, title 21, Code of Federal Regulations. Original food classification in LanguaL.

chemical food component
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: part of
  some values from: food material
IAO_0000115: Any chemical or chemical mixture that exists in a food material or was added to a food material.

mammal
type: Class
subclass of: vertebrate animal food product
subclass of: vertebrate animal
IAO_0000115: Mammals (from Latin mamma "breast") are vertebrate animals constituting the class Mammalia, and characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or hair, and three middle ear bones.

vertebrate animal
type: Class
subclass of: animal
IAO_0000115: A vertebrate animal is any species of organism within the subphylum Vertebrata (chordates with backbones). Vertebrates represent the overwhelming majority of the phylum Chordata, with currently about 69,276 species described.
has broad synonym: animal

food product organismal source
type: Class
subclass of: organism
IAO_0000115: This is a hierarchy of organisms, grouped minimally in a combination of taxonomy and consumer-oriented food groups.

food additive
type: Class
subclass of: chemical food component

food treatment process
type: Class
subclass of: food transformation process
IAO_0000115: Used to specifically characterize a food product based on the treatment or processes applied to the product or any indexed ingredient. The processes include adding, substituting or removing components or modifying the food or component, e.g., through fermentation.

microbial/enzymatic modification process
type: Class
subclass of: food modification process
IAO_0000115: A food modification process by microbial or enzymatic action which results in molecular changes in any food component.

food modification process
type: Class
subclass of: food treatment process

food preservation process
type: Class
subclass of: food transformation process
IAO_0000115: The methods contributing to the prevention or retardation of microbial, enzymatic or oxidative spoilage and thus to the extension of shelf life. Index all methods for which information is available, even if a corresponding descriptor has already been used in *H. TREATMENT APPLIED*. Preservation descriptors refer to the finished food as a whole with these exceptions: (1) if the components of a multi-component food, such as cream pie, are preservation by different methods, index all methods; (2) if chemical preservatives are declared on the label, always index them even if it is known that the preservative was introduced through or is only present in a component or ingredient of the food; and (3) if the preservation method for an ingredient is declared on the label (such as brie cheese made from pasteurized milk) index it. Also use *INGREDIENT preservation by THERMAL PROCESSING* or *INGREDIENT preservation by IRRADIATION* when ingredients have been pasteurized, ultrapasteurized, sterilized or irradiated.

molecular_function
type: Class
subclass of: process
IAO_0000115: A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
has exact synonym: molecular function

catalytic activity
type: Class
subclass of: molecular_function
IAO_0000115: Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
has exact synonym: enzyme activity

phosphorus metabolic process
type: Class
subclass of: cellular metabolic process
IAO_0000115: The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
has exact synonym: phosphorus metabolism

phosphate-containing compound metabolic process
type: Class
subclass of: phosphorus metabolic process
IAO_0000115: The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
has exact synonym: phosphate metabolism
has related synonym: phosphate metabolic process

biological_process
type: Class
subclass of: process
IAO_0000115: A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
has exact synonym: biological process
has exact synonym: physiological process
has related synonym: single organism process
has related synonym: single-organism process

metabolic process
type: Class
subclass of: biological_process
IAO_0000115: The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
has exact synonym: metabolism
has narrow synonym: metabolic process resulting in cell growth
has narrow synonym: metabolism resulting in cell growth
has narrow synonym: multicellular organism metabolic process
has related synonym: single-organism metabolic process

cellular process
type: Class
subclass of: biological_process
IAO_0000115: Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
has exact synonym: cell physiology
has exact synonym: cellular physiological process
has narrow synonym: cell growth and/or maintenance
has related synonym: single-organism cellular process

kinase activity
type: Class
subclass of: transferase activity, transferring phosphorus-containing groups
subclass of: Restriction
  on property: part of
  some values from: phosphorylation
subclass of: Restriction
  on property: is kinase activity
  has self: true
IAO_0000115: Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
has exact synonym: phosphokinase activity

phosphorylation
type: Class
subclass of: phosphate-containing compound metabolic process
IAO_0000115: The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

transferase activity
type: Class
subclass of: catalytic activity
IAO_0000115: Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

transferase activity, transferring phosphorus-containing groups
type: Class
subclass of: transferase activity
IAO_0000115: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

cellular metabolic process
type: Class
subclass of: metabolic process
subclass of: cellular process
IAO_0000115: The chemical reactions and pathways by which individual cells transform chemical substances.
has exact synonym: cellular metabolism
has related synonym: intermediary metabolism

All
type: Class

Phenotypic abnormality
type: Class
equivalent class: Restriction
  on property: has part
  some values from: Class
    intersection of: quality
    intersection of: Restriction
      on property: inheres in part of
      some values from: multicellular organism
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
subclass of: All
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: quality
    intersection of: Restriction
      on property: inheres in part of
      some values from: multicellular organism
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
IAO_0000115: A phenotypic abnormality.
has exact synonym: Organ abnormality

Abnormality of metabolism/homeostasis
type: Class
equivalent class: Restriction
  on property: has part
  some values from: Class
    intersection of: quality
    intersection of: Restriction
      on property: inheres in part of
      some values from: metabolic process
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
subclass of: Phenotypic abnormality
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: quality
    intersection of: Restriction
      on property: inheres in part of
      some values from: metabolic process
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
has exact synonym: Laboratory abnormality
has exact synonym: Metabolism abnormality

objective specification
type: Class
subclass of: directive information entity
IAO_0000115: A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.
IAO_0000115: a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.

action specification
type: Class
subclass of: directive information entity
IAO_0000115: A directive information entity that describes an action the bearer will take.
IAO_0000115: a directive information entity that describes an action the bearer will take

data item
type: Class
subclass of: information content entity
IAO_0000115: An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.
IAO_0000115: a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.

information content entity
type: Class
subclass of: generically dependent continuant
subclass of: Restriction
  on property: is about
  some values from: entity
IAO_0000115: A generically dependent continuant that is about some thing.

directive information entity
type: Class
subclass of: information content entity
subclass of: Restriction
  on property: is about
  some values from: realizable entity
IAO_0000115: An information content entity whose concretizations indicate to their bearer how to realize them in a process.

curation status specification
type: Class
equivalent class: Class
  one of: example to be eventually removed
  one of: metadata complete
  one of: organizational term
  one of: ready for release
  one of: metadata incomplete
  one of: uncurated
  one of: pending final vetting
  one of: to be replaced with external ontology term
  one of: requires discussion
subclass of: data about an ontology part
IAO_0000115: The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.

data about an ontology part
type: Class
subclass of: data item
IAO_0000115: Data about an ontology part is a data item about a part of an ontology, for example a term
IAO_0000115: data about an ontology part is a data item about a part of an ontology, for example a term

plan specification
type: Class
subclass of: directive information entity
subclass of: Restriction
  on property: has part
  some values from: objective specification
subclass of: Restriction
  on property: has part
  some values from: action specification
IAO_0000115: A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.

material information bearer
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: bearer of
    some values from: Restriction
      on property: concretizes
      some values from: information content entity
subclass of: material entity
subclass of: Restriction
  on property: bearer of
  some values from: Restriction
    on property: concretizes
    some values from: information content entity
IAO_0000115: A material entity in which a concretization of an information content entity inheres.

obsolescence reason specification
type: Class
equivalent class: Class
  one of: failed exploratory term
  one of: placeholder removed
  one of: terms merged
  one of: term imported
  one of: term split
subclass of: data about an ontology part
IAO_0000115: The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.

denotator type
type: Class
equivalent class: Class
  one of: universal
  one of: defined class
  one of: named class expression
subclass of: data about an ontology part
IAO_0000115: A denotator type indicates how a term should be interpreted from an ontological perspective.

pathological entity
type: Class
subclass of: pathological phenotype observation
IAO_0000115: Pathological structure or process

pathological phenotype observation
type: Class
IAO_0000115: Phenotypic observation of the presence or absence of a pathological entity.

pathological anatomical entity
type: Class
subclass of: pathological entity
IAO_0000115: Anatomically located instance of pathological response or entity.

healing and repair structure
type: Class
subclass of: pathological anatomical entity
IAO_0000115: Physical entity or structure associated with normal or abnormal tissue healing or repair following extrinsic or intrinsic damage.

abscess
type: Class
subclass of: healing and repair structure
IAO_0000115: A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation.

root
type: Class
subclass of: material entity
has related synonym: all

Viruses
type: Class
subclass of: root
subclass of: organism
has related synonym: Vira
has related synonym: Viridae
has related synonym: viruses

Teleostomi
type: Class
subclass of: Gnathostomata <vertebrates>

Euteleostomi
type: Class
subclass of: Teleostomi
has exact synonym: bony vertebrates

cellular organisms
type: Class
subclass of: root
has related synonym: biota

Dipnotetrapodomorpha
type: Class
subclass of: Sarcopterygii

Boreoeutheria
type: Class
subclass of: Eutheria
has related synonym: Boreotheria

Bacteria
type: Class
subclass of: cellular organisms
subclass of: organism
has exact synonym: eubacteria
has related synonym: Monera
has related synonym: Procaryotae
has related synonym: Prokaryota
has related synonym: Prokaryotae
has related synonym: bacteria
has related synonym: prokaryote
has related synonym: prokaryotes

Homininae
type: Class
subclass of: Hominidae
has related synonym: Homo/Pan/Gorilla group

Archaea
type: Class
subclass of: organism

Eukaryota
type: Class
subclass of: cellular organisms
subclass of: organism
has exact synonym: eucaryotes
has exact synonym: eukaryotes
has related synonym: Eucarya
has related synonym: Eucaryotae
has related synonym: Eukarya
has related synonym: Eukaryotae
has related synonym: eukaryotes

Euarchontoglires
type: Class
subclass of: Boreoeutheria

Simiiformes
type: Class
subclass of: Haplorrhini
has related synonym: Anthropoidea

Hominoidea
type: Class
subclass of: Catarrhini
has exact synonym: ape
has exact synonym: apes

Tetrapoda
type: Class
subclass of: Dipnotetrapodomorpha
has exact synonym: tetrapods

Amniota
type: Class
subclass of: Tetrapoda
has exact synonym: amniotes

Theria <mammals>
type: Class
subclass of: Mammalia
has exact synonym: Theria

Opisthokonta
type: Class
subclass of: Eukaryota
has related synonym: Fungi/Metazoa group
has related synonym: opisthokonts

Metazoa
type: Class
subclass of: Opisthokonta
has exact synonym: metazoans
has exact synonym: multicellular animals
has related synonym: Animalia
has related synonym: animals

Bilateria
type: Class
subclass of: Eumetazoa

Deuterostomia
type: Class
subclass of: Bilateria
has exact synonym: deuterostomes

Haplorrhini
type: Class
subclass of: Primates

Mammalia
type: Class
subclass of: Amniota
has exact synonym: mammals
has related synonym: mammals

Eumetazoa
type: Class
subclass of: Metazoa

Chordata
type: Class
subclass of: Deuterostomia
has exact synonym: chordates
has related synonym: chordates

Vertebrata <Metazoa>
type: Class
subclass of: Craniata <chordates>
has exact synonym: Vertebrata
has exact synonym: vertebrates
has related synonym: vertebrates
label: Vertebrata <vertebrates>

Gnathostomata <vertebrates>
type: Class
subclass of: Vertebrata <Metazoa>
has exact synonym: Gnathostomata
has exact synonym: jawed vertebrates

Sarcopterygii
type: Class
subclass of: Euteleostomi

Craniata <chordates>
type: Class
subclass of: Chordata
has exact synonym: Craniata

Eutheria
type: Class
subclass of: Theria <mammals>
has exact synonym: eutherian mammals
has exact synonym: placental mammals
has exact synonym: placentals
has related synonym: Placentalia
has related synonym: placentals

Primates
type: Class
subclass of: Euarchontoglires
has exact synonym: primate
has related synonym: Primata
has related synonym: primates

Catarrhini
type: Class
subclass of: Simiiformes

Hominidae
type: Class
subclass of: Hominoidea
has exact synonym: great apes
has related synonym: Pongidae

Homo
type: Class
subclass of: Homininae
has exact synonym: humans

Homo sapiens
type: Class
subclass of: mammal
subclass of: Homo
has exact synonym: human
has exact synonym: man

Alcohol Consumption
type: Class
subclass of: Personal Behavior
IAO_0000115: Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol.
has exact synonym: Alcohol Consumption

Behavior
type: Class
subclass of: Activity
IAO_0000115: The actions or reactions of an object or organism, usually in relation to the environment or surrounding world of stimuli.
has exact synonym: Attitude
has exact synonym: Behavior
has exact synonym: Behavioral
has exact synonym: Conduct

Occupation or Discipline
type: Class
subclass of: Conceptual Entity
IAO_0000115: A grouping of occupations and fields of study.
has exact synonym: Occupation or Discipline

Personal Behavior
type: Class
subclass of: Behavior
IAO_0000115: The observable response of a person.
has exact synonym: Personal Behavior
has exact synonym: Personal Conduct

Conceptual Entity
type: Class
IAO_0000115: An organizational header for concepts representing mostly abstract entities.
has exact synonym: Conceptual Entity

Occupation
type: Class
subclass of: Occupation or Discipline
IAO_0000115: The principal activity that a person does to earn money.
has exact synonym: EMPJOB
has exact synonym: Employee Job
has exact synonym: Job
has exact synonym: OCCUPATION
has exact synonym: Occupation

Activity
type: Class
IAO_0000115: An active process; excludes processes and mechanisms which fulfill biological functions.
has exact synonym: Activity
has exact synonym: General activity

planned process
type: Class
equivalent class: Restriction
  on property: realizes
  some values from: Restriction
    on property: concretizes
    some values from: plan specification
subclass of: process
subclass of: Restriction
  on property: realizes
  some values from: Restriction
    on property: concretizes
    some values from: plan specification
IAO_0000115: A process that realizes a plan which is the concretization of a plan specification.
IAO_0000115: A processual entity that realizes a plan which is the concretization of a plan specification.

specimen role
type: Class
subclass of: role
subclass of: Restriction
  on property: inheres in
  some values from: Class
    intersection of: material entity
    intersection of: Restriction
      on property: is_specified_output_of
      some values from: specimen collection process
IAO_0000115: a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation

specimen collection process
type: Class
equivalent class: Class
  intersection of: planned process
  intersection of: Restriction
    on property: achieves_planned_objective
    some values from: specimen collection objective
subclass of: planned process
subclass of: Restriction
  on property: has_specified_input
  some values from: material entity
subclass of: Restriction
  on property: has_specified_output
  some values from: specimen
subclass of: Restriction
  on property: achieves_planned_objective
  some values from: specimen collection objective
IAO_0000115: A planned process with the objective of collecting a specimen.

specimen collection objective
type: Class
subclass of: objective specification
IAO_0000115: A objective specification to obtain a material entity for potential use as an input during an investigation.

collection of specimens
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has member
    all values from: specimen
subclass of: material entity
IAO_0000115: A material entity that has two or more specimens as its parts.

organism
type: Class
equivalent class: Class
  union of: Viruses
  union of: Bacteria
  union of: Archaea
  union of: Eukaryota
subclass of: material entity
IAO_0000115: A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.

specimen
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has role
    some values from: specimen role
subclass of: material entity
subclass of: Restriction
  on property: has role
  some values from: specimen role
IAO_0000115: A material entity that has the specimen role.

quality
type: Class
subclass of: specifically dependent continuant
IAO_0000115: A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities

qualitative
type: Class
subclass of: quality

deviation (from_normal)
type: Class
subclass of: qualitative
IAO_0000115: A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.

amount
type: Class
subclass of: qualitative
subclass of: Restriction
  on property: reciprocal_of
  some values from: has number of
IAO_0000115: The number of entities of this type that are part of the whole organism.
has exact synonym: presence or absence in organism
has exact synonym: quantitative
has related synonym: count in organism
has related synonym: number
has related synonym: presence

temperature
type: Class
subclass of: physical quality
IAO_0000115: A physical quality of the thermal energy of a system.

abnormal
type: Class
subclass of: deviation (from_normal)
IAO_0000115: A quality inhering in a bearer by virtue of the bearer's deviation from normal or average.
has related synonym: aberrant
has related synonym: atypia
has related synonym: atypical
has related synonym: defective

normal
type: Class
subclass of: qualitative
IAO_0000115: A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.
has related synonym: average

present
type: Class
subclass of: amount
IAO_0000115: A quality inhering in a bearer by virtue of the bearer's existence.
has related synonym: present in organism

increased amount
type: Class
equivalent class: Class
  intersection of: amount
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
equivalent class: Restriction
  on property: has part
  some values from: Class
    intersection of: increased amount
    intersection of: Restriction
      on property: inheres in
      some values from: abscess
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
subclass of: present
subclass of: increased quality
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: increased amount
    intersection of: Restriction
      on property: inheres in
      some values from: abscess
    intersection of: Restriction
      on property: has modifier
      some values from: abnormal
IAO_0000115: An amount which is relatively high.
has exact synonym: increased number
has exact synonym: present in greater numbers in organism
has exact synonym: supernumerary
has related synonym: accessory
has related synonym: increased

physical quality
type: Class
subclass of: physical object quality
IAO_0000115: A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities.
has exact synonym: relational physical quality

pressure
type: Class
subclass of: physical quality
IAO_0000115: A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts.

process quality
type: Class
subclass of: quality
IAO_0000115: A quality which inheres in an process.
has exact synonym: quality of a process
has exact synonym: quality of occurrent
has exact synonym: quality of process
has exact synonym: relational quality of occurrent

physical object quality
type: Class
subclass of: quality
IAO_0000115: A quality which inheres in a continuant.
has exact synonym: monadic quality of a continuant
has exact synonym: multiply inhering quality of a physical entity
has exact synonym: quality of a continuant
has exact synonym: quality of a single physical entity
has exact synonym: quality of an object
has exact synonym: quality of continuant
has narrow synonym: monadic quality of an object
has narrow synonym: monadic quality of continuant

increased temperature
type: Class
equivalent class: Class
  intersection of: temperature
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
subclass of: temperature
subclass of: increased object quality
IAO_0000115: A temperature which is relatively high.
has exact synonym: high temperature
has exact synonym: hot

decreased temperature
type: Class
equivalent class: Class
  intersection of: temperature
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: temperature
subclass of: decreased object quality
IAO_0000115: A temperature which is relatively low.
has exact synonym: cold
has exact synonym: low temperature

has number of
type: Class
subclass of: physical object quality
subclass of: Restriction
  on property: reciprocal_of
  some values from: amount
IAO_0000115: The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts.
has exact synonym: extra or missing physical or functional parts
has exact synonym: has or lacks parts of type
has exact synonym: mereological quality
has exact synonym: number of
has related synonym: cardinality
has related synonym: number

decreased pressure
type: Class
equivalent class: Class
  intersection of: pressure
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: pressure
subclass of: decreased object quality
IAO_0000115: A pressure which is relatively low.
has exact synonym: low pressure

increased pressure
type: Class
equivalent class: Class
  intersection of: pressure
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
subclass of: pressure
subclass of: increased object quality
IAO_0000115: A pressure which is relatively high.
has exact synonym: high pressure

decreased amount
type: Class
equivalent class: Class
  intersection of: amount
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: present
subclass of: decreased quality
IAO_0000115: An amount which is relatively low.
has exact synonym: decreased number
has exact synonym: present in fewer numbers in organism
has related synonym: decreased
has related synonym: reduced
has related synonym: subnumerary

increased quality
type: Class
equivalent class: Class
  intersection of: quality
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
subclass of: deviation (from_normal)
subclass of: Restriction
  on property: increased_in_magnitude_relative_to
  some values from: normal
IAO_0000115: A quality that has a value that is increased compared to normal or average.

decreased quality
type: Class
equivalent class: Class
  intersection of: quality
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: deviation (from_normal)
subclass of: Restriction
  on property: decreased_in_magnitude_relative_to
  some values from: normal
IAO_0000115: A quality that has a value that is decreased compared to normal or average.

decreased process quality
type: Class
equivalent class: Class
  intersection of: process quality
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: process quality
subclass of: decreased quality
IAO_0000115: A quality of a process that has a value that is decreased compared to normal or average.

decreased object quality
type: Class
equivalent class: Class
  intersection of: physical object quality
  intersection of: Restriction
    on property: decreased_in_magnitude_relative_to
    some values from: normal
subclass of: physical object quality
subclass of: decreased quality
IAO_0000115: A quality of an object that has a value that is decreased compared to normal or average.

increased process quality
type: Class
equivalent class: Class
  intersection of: process quality
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
subclass of: process quality
subclass of: increased quality
IAO_0000115: A quality of a process that has a value that is increased compared to normal or average.

increased object quality
type: Class
equivalent class: Class
  intersection of: physical object quality
  intersection of: Restriction
    on property: increased_in_magnitude_relative_to
    some values from: normal
subclass of: physical object quality
subclass of: increased quality
IAO_0000115: A quality of an object that has a value that is increased compared to normal or average.

exposure event or process
type: Class
subclass of: process
IAO_0000115: A process occurring within or in the vicinity of an organism that exerts some causal influence on the organism via the interaction between an exposure stimulus and an exposure receptor. The exposure stimulus may be a process, material entity or condition (for example, lack of nutrients). The exposure receptor can be an organism, organism population or a part of an organism.

processual entity
type: Class
IAO_0000115: An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity.

anatomical structure
type: Class
subclass of: material anatomical entity
subclass of: Restriction
  on property: existence starts during or after
  some values from: zygote stage
subclass of: Restriction
  on property: existence ends during or before
  some values from: death stage
IAO_0000115: Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
has exact synonym: biological structure
has exact synonym: connected biological structure

fully formed stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: post-embryonic stage
subclass of: Restriction
  on property: preceded_by
  some values from: organogenesis stage
subclass of: Restriction
  on property: precedes
  some values from: death stage
IAO_0000115: The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage.
has broad synonym: adult stage
has exact synonym: fully formed animal stage
has exact synonym: juvenile-adult stage

embryo stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: precedes
  some values from: fully formed stage
subclass of: Restriction
  on property: precedes
  some values from: post-embryonic stage
IAO_0000115: A life cycle stage that starts with fertilization and ends with the fully formed embryo.
has exact synonym: embryonic stage
has related synonym: embryogenesis

death stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: ends
  some values from: life cycle
IAO_0000115: End of the life of an organism.
has related synonym: death

post-embryonic stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: preceded_by
  some values from: embryo stage
IAO_0000115: stage succeeding embryo, including mature structure
has exact synonym: postembryonic stage
has narrow synonym: post-hatching stage
has related synonym: postembryonic

life cycle
type: Class
subclass of: processual entity
subclass of: Restriction
  on property: has part
  some values from: life cycle stage
subclass of: Restriction
  on property: starts with
  some values from: zygote stage
subclass of: Restriction
  on property: ends with
  some values from: death stage
IAO_0000115: An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism.
has exact synonym: entire life cycle
has exact synonym: entire lifespan
has exact synonym: life
has exact synonym: lifespan

life cycle stage
type: Class
subclass of: processual entity
subclass of: Restriction
  on property: part of
  some values from: life cycle
IAO_0000115: A spatiotemporal region encompassing some part of the life cycle of an organism.
has narrow synonym: developmental stage
has narrow synonym: stage

zygote stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: starts
  some values from: life cycle
IAO_0000115: A stage at which the organism is a single cell produced by means of sexual reproduction.
has exact synonym: 1-cell stage
has exact synonym: fertilized egg stage
has exact synonym: one cell stage
has related synonym: fertilized egg stage
has related synonym: one-cell stage
has related synonym: zygote
has related synonym: zygotum

cleavage stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: immediately_preceded_by
  some values from: zygote stage
IAO_0000115: The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula.

blastula stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: preceded_by
  some values from: cleavage stage
IAO_0000115: An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence.

gastrula stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: preceded_by
  some values from: blastula stage
IAO_0000115: A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
has related synonym: blastocystis trilaminaris stage
has related synonym: trilaminar blastocyst stage
has related synonym: trilaminar blastoderm stage
has related synonym: trilaminar disk stage
has related synonym: trilaminar germ stage
has related synonym: trilaminar stage

neurula stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: preceded_by
  some values from: gastrula stage
IAO_0000115: Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.

organogenesis stage
type: Class
subclass of: occurrent
subclass of: life cycle stage
subclass of: Restriction
  on property: part of
  some values from: embryo stage
subclass of: Restriction
  on property: preceded_by
  some values from: neurula stage
IAO_0000115: A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism.
has related synonym: segmentation stage

material anatomical entity
type: Class
subclass of: material entity
subclass of: anatomical entity
IAO_0000115: Anatomical entity that has mass.

multicellular organism
type: Class
subclass of: multicellular anatomical structure
IAO_0000115: Anatomical structure that is an individual member of a species and consists of more than one cell.
has broad synonym: organism
has exact synonym: multi-cellular organism
has narrow synonym: animal
has related synonym: Koerper
has related synonym: body
has related synonym: whole body
has related synonym: whole organism

anatomical entity
type: Class
subclass of: independent continuant
IAO_0000115: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.

multicellular anatomical structure
type: Class
subclass of: anatomical structure
IAO_0000115: An anatomical structure that has more than one cell as a part.
has exact synonym: multicellular structure

example to be eventually removed
type: NamedIndividual
type: curation status specification

failed exploratory term
type: NamedIndividual
IAO_0000115: The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job

metadata complete
type: NamedIndividual
type: curation status specification
IAO_0000115: Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.

organizational term
type: NamedIndividual
type: curation status specification
IAO_0000115: Term created to ease viewing/sort terms for development purpose, and will not be included in a release
IAO_0000115: term created to ease viewing/sort terms for development purpose, and will not be included in a release

ready for release
type: NamedIndividual
type: curation status specification
IAO_0000115: Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release."

metadata incomplete
type: NamedIndividual
type: curation status specification
IAO_0000115: Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.

uncurated
type: NamedIndividual
type: curation status specification
IAO_0000115: Nothing done yet beyond assigning a unique class ID and proposing a preferred term.

pending final vetting
type: NamedIndividual
type: curation status specification
IAO_0000115: All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.

placeholder removed
type: NamedIndividual

terms merged
type: NamedIndividual

term imported
type: NamedIndividual

term split
type: NamedIndividual

universal
type: NamedIndividual

defined class
type: NamedIndividual
IAO_0000115: A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal

named class expression
type: NamedIndividual
IAO_0000115: A named class expression is a logical expression that is given a name. The name can be used in place of the expression.

to be replaced with external ontology term
type: NamedIndividual
type: curation status specification
IAO_0000115: Terms with this status should eventually replaced with a term from another ontology.

requires discussion
type: NamedIndividual
type: curation status specification
IAO_0000115: A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.