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        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002161",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_40674"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0000805",
      "lbl" : "X chromosome",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.",
          "xrefs" : [ "GOC:mah", "GOC:mr", "ISBN:0582227089", "PMID:20622855", "Wikipedia:XY_sex-determination_system" ]
        },
        "xrefs" : [ {
          "val" : "Wikipedia:X_chromosome"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002161",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_8782"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0000806",
      "lbl" : "Y chromosome",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.",
          "xrefs" : [ "GOC:mah", "GOC:mr", "ISBN:0582227089", "PMID:20622855", "Wikipedia:XY_sex-determination_system" ]
        },
        "xrefs" : [ {
          "val" : "Wikipedia:Y_chromosome"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002161",
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        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0000807",
      "lbl" : "Z chromosome",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.",
          "xrefs" : [ "GOC:mah", "GOC:mr", "ISBN:0321000382", "PMID:20622855" ]
        },
        "xrefs" : [ {
          "val" : "Wikipedia:ZW_sex-determination_system"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002161",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_40674"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0003674",
      "lbl" : "molecular_function",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.",
          "xrefs" : [ "GOC:pdt" ]
        },
        "comments" : [ "Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.", "This is the same as GO molecular function" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecular function"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005575",
      "lbl" : "cellular_component",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).",
          "xrefs" : [ "GOC:pdt" ]
        },
        "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "cell or subcellular entity"
        }, {
          "pred" : "hasExactSynonym",
          "val" : "cellular component"
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "subcellular entity",
          "xrefs" : [ "NIF_Subcellular:nlx_subcell_100315" ]
        } ],
        "xrefs" : [ {
          "val" : "NIF_Subcellular:sao1337158144"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
          "val" : "https://github.com/geneontology/go-ontology/issues/17729"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
          "val" : "GO:0008372"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005622",
      "lbl" : "intracellular anatomical structure",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.",
          "xrefs" : [ "ISBN:0198506732" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "internal to cell"
        }, {
          "pred" : "hasExactSynonym",
          "val" : "intracellular"
        }, {
          "pred" : "hasExactSynonym",
          "val" : "protoplasm"
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "nucleocytoplasm",
          "xrefs" : [ "GOC:mah" ]
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "protoplast",
          "xrefs" : [ "GOC:mah" ]
        } ],
        "xrefs" : [ {
          "val" : "Wikipedia:Intracellular"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
          "val" : "https://github.com/geneontology/go-ontology/issues/17776"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005634",
      "lbl" : "nucleus",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",
          "xrefs" : [ "GOC:go_curators" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "cell nucleus"
        }, {
          "pred" : "hasNarrowSynonym",
          "val" : "horsetail nucleus",
          "xrefs" : [ "GOC:al", "GOC:mah", "GOC:vw", "PMID:15030757" ]
        } ],
        "xrefs" : [ {
          "val" : "NIF_Subcellular:sao1702920020"
        }, {
          "val" : "Wikipedia:Cell_nucleus"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005635",
      "lbl" : "nuclear envelope",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).",
          "xrefs" : [ "ISBN:0198547684" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
        "xrefs" : [ {
          "val" : "Wikipedia:Nuclear_envelope"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
          "val" : "GO:0005636"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005694",
      "lbl" : "chromosome",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.",
          "xrefs" : [ "ISBN:0198547684" ]
        },
        "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasNarrowSynonym",
          "val" : "interphase chromosome"
        }, {
          "pred" : "hasNarrowSynonym",
          "val" : "prophase chromosome"
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "chromatid"
        } ],
        "xrefs" : [ {
          "val" : "Wikipedia:Chromosome"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005737",
      "lbl" : "cytoplasm",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",
          "xrefs" : [ "ISBN:0198547684" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "xrefs" : [ {
          "val" : "Wikipedia:Cytoplasm"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
          "val" : "https://github.com/geneontology/go-ontology/issues/23023"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005739",
      "lbl" : "mitochondrion",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",
          "xrefs" : [ "GOC:giardia", "ISBN:0198506732" ]
        },
        "comments" : [ "Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "mitochondria"
        } ],
        "xrefs" : [ {
          "val" : "NIF_Subcellular:sao1860313010"
        }, {
          "val" : "Wikipedia:Mitochondrion"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005740",
      "lbl" : "mitochondrial envelope",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.",
          "xrefs" : [ "GOC:ai", "GOC:pz" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "basicPropertyValues" : [ {
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          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005759",
      "lbl" : "mitochondrial matrix",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",
          "xrefs" : [ "GOC:as", "ISBN:0198506732" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "mitochondrial lumen"
        }, {
          "pred" : "hasNarrowSynonym",
          "val" : "mitochondrial stroma"
        } ],
        "xrefs" : [ {
          "val" : "NIF_Subcellular:sao1804523077"
        }, {
          "val" : "Wikipedia:Mitochondrial_matrix"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
          "val" : "GO:0031980"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005773",
      "lbl" : "vacuole",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.",
          "xrefs" : [ "GOC:mtg_sensu", "ISBN:0198506732" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "vacuolar carboxypeptidase Y"
        } ],
        "xrefs" : [ {
          "val" : "Wikipedia:Vacuole"
        } ],
        "basicPropertyValues" : [ {
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          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005775",
      "lbl" : "vacuolar lumen",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The volume enclosed within the vacuolar membrane.",
          "xrefs" : [ "ISBN:0198506732" ]
        },
        "basicPropertyValues" : [ {
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      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005829",
      "lbl" : "cytosol",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",
          "xrefs" : [ "GOC:hjd", "GOC:jl" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
        "xrefs" : [ {
          "val" : "NIF_Subcellular:sao101633890"
        }, {
          "val" : "Wikipedia:Cytosol"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "cellular_component"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005886",
      "lbl" : "plasma membrane",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",
          "xrefs" : [ "ISBN:0716731363" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ],
        "synonyms" : [ {
          "pred" : "hasBroadSynonym",
          "val" : "juxtamembrane"
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          "pred" : "hasExactSynonym",
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        }, {
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          "pred" : "hasExactSynonym",
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          "val" : "bacterial inner membrane"
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          "pred" : "hasNarrowSynonym",
          "val" : "inner endospore membrane"
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          "pred" : "hasNarrowSynonym",
          "val" : "integral component of plasma membrane"
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          "pred" : "hasNarrowSynonym",
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        "definition" : {
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          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9483",
      "lbl" : "Callithrix jacchus",
      "type" : "CLASS",
      "meta" : {
        "synonyms" : [ {
          "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003",
          "pred" : "hasExactSynonym",
          "val" : "common marmoset"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003",
          "pred" : "hasExactSynonym",
          "val" : "white ear-tufted marmoset"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name",
          "pred" : "hasExactSynonym",
          "val" : "white-tufted-ear marmoset"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym",
          "pred" : "hasRelatedSynonym",
          "val" : "Callithrix jacchus jacchus"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym",
          "pred" : "hasRelatedSynonym",
          "val" : "Simia jacchus"
        } ],
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_species"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
          "val" : "NCBITaxon:9484"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9498",
      "lbl" : "Cebidae",
      "type" : "CLASS",
      "meta" : {
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_family"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9526",
      "lbl" : "Catarrhini",
      "type" : "CLASS",
      "meta" : {
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_parvorder"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9604",
      "lbl" : "Hominidae",
      "type" : "CLASS",
      "meta" : {
        "synonyms" : [ {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name",
          "pred" : "hasExactSynonym",
          "val" : "great apes"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym",
          "pred" : "hasRelatedSynonym",
          "val" : "Pongidae"
        } ],
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_family"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9605",
      "lbl" : "Homo",
      "type" : "CLASS",
      "meta" : {
        "synonyms" : [ {
          "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003",
          "pred" : "hasExactSynonym",
          "val" : "humans"
        } ],
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_genus"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9606",
      "lbl" : "Homo sapiens",
      "type" : "CLASS",
      "meta" : {
        "synonyms" : [ {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name",
          "pred" : "hasExactSynonym",
          "val" : "human"
        } ],
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_species"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/NCBITaxon_9989",
      "lbl" : "Rodentia",
      "type" : "CLASS",
      "meta" : {
        "synonyms" : [ {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name",
          "pred" : "hasExactSynonym",
          "val" : "rodent"
        }, {
          "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name",
          "pred" : "hasRelatedSynonym",
          "val" : "rodents"
        } ],
        "xrefs" : [ {
          "val" : "GC_ID:1"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/ncbitaxon#has_rank",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_order"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "ncbi_taxonomy"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/OBI_0100026",
      "lbl" : "organism",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "organism"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "animal"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "fungus"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "plant"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "virus"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "13-02-2009:\nOBI doesn't take position as to  when an organism starts or ends being an organism - e.g. sperm, foetus.\nThis issue is outside the scope of OBI."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "GROUP: OBI Biomaterial Branch"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "WEB: http://en.wikipedia.org/wiki/Organism"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000001",
      "lbl" : "quality",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities",
          "xrefs" : [ "PATOC:GVG" ]
        }
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/UBERON_0001062",
      "lbl" : "anatomical entity",
      "type" : "CLASS",
      "meta" : {
        "definition" : {
          "val" : "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.",
          "xrefs" : [ "FMA:62955", "http://orcid.org/0000-0001-9114-8737" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ],
        "xrefs" : [ {
          "val" : "AAO:0010841"
        }, {
          "val" : "AEO:0000000"
        }, {
          "val" : "BFO:0000004"
        }, {
          "val" : "BILA:0000000"
        }, {
          "val" : "BIRNLEX:6"
        }, {
          "val" : "CARO:0000000"
        }, {
          "val" : "EHDAA2:0002229"
        }, {
          "val" : "FMA:62955"
        }, {
          "val" : "HAO:0000000"
        }, {
          "val" : "MA:0000001"
        }, {
          "val" : "NCIT:C12219"
        }, {
          "val" : "TAO:0100000"
        }, {
          "val" : "TGMA:0001822"
        }, {
          "val" : "UMLS:C1515976"
        }, {
          "val" : "WBbt:0000100"
        }, {
          "val" : "XAO:0000000"
        }, {
          "val" : "ZFA:0100000"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002175",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002175",
          "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000050",
      "lbl" : "part of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a core relation that holds between a part and its whole"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "xrefs" : [ {
          "val" : "BFO:0000050"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "is part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my brain is part of my body (continuant parthood, two material entities)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this day is part of this year (occurrent parthood)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "part_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000004"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000017"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000019"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000020"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000031"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "external"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "part_of"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:part_of"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Part_of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
      "lbl" : "has part",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a core relation that holds between a whole and its part"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "xrefs" : [ {
          "val" : "BFO:0000051"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "has part"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my body has part my brain (continuant parthood, two material entities)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this year has part this day (occurrent parthood)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_part"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
          "val" : "external"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "has_part"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000062",
      "lbl" : "preceded by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "preceded by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C.    The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is preceded by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "preceded_by"
        }, {
          "pred" : "http://purl.org/dc/terms/source",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000063",
      "lbl" : "precedes",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "precedes"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000052",
      "lbl" : "characteristic of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."
        },
        "comments" : [ "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "inheres in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this fragility is a characteristic of this vase"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this red color is a characteristic of this apple"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "inheres_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000053",
      "lbl" : "has characteristic",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Inverse of characteristic_of"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "bearer of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this apple is bearer of this red color"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this vase is bearer of this fragility"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "bearer_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is bearer of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000056",
      "lbl" : "participates in",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a continuant and a process, in which the continuant is somehow involved in the process"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "participates in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this blood clot participates in this blood coagulation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this input material (or this output material) participates in this process"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigator participates in this investigation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "participates_in"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000057",
      "lbl" : "has participant",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a process and a continuant, in which the continuant is somehow involved in the process"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "has participant"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this blood coagulation has participant this blood clot"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigation has participant this investigator"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this process has participant this input material (or this output material)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_participant"
        }, {
          "pred" : "http://purl.org/dc/terms/source",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000079",
      "lbl" : "function of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this catalysis function is a function of this enzyme"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "function_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is function of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000080",
      "lbl" : "quality of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this red color is a quality of this apple"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A quality inheres in its bearer at all times for which the quality exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is quality of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "quality_of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000081",
      "lbl" : "role of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigator role is a role of this person"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is role of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "role_of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000085",
      "lbl" : "has function",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_function"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000086",
      "lbl" : "has quality",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this apple has quality this red color"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_quality"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000087",
      "lbl" : "has role",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this person has role this investigator role (more colloquially: this person has this role of investigator)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_role"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000091",
      "lbl" : "has disposition",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"
        }
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000092",
      "lbl" : "disposition of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of has disposition"
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002013",
      "lbl" : "has regulatory component activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:30:46Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002014",
      "lbl" : "has negative regulatory component activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B."
        },
        "comments" : [ "By convention GO molecular functions are classified by their effector function.  Internal regulatory functions are treated as components.  For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:31:01Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002015",
      "lbl" : "has positive regulatory component activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B."
        },
        "comments" : [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components.  So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:31:17Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002017",
      "lbl" : "has component activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:44:33Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002018",
      "lbl" : "has component process",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:49:21Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002022",
      "lbl" : "directly regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:24Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002023",
      "lbl" : "directly negatively regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
          "xrefs" : [ "https://orcid.org/0000-0002-7073-9172" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:38Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002024",
      "lbl" : "directly positively regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
          "xrefs" : [ "https://orcid.org/0000-0002-7073-9172" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:47Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002025",
      "lbl" : "has effector activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.",
          "xrefs" : [ "https://orcid.org/0000-0002-7073-9172" ]
        },
        "comments" : [ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-22T14:14:36Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002086",
      "lbl" : "ends after",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002087",
      "lbl" : "immediately preceded by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "starts_at_end_of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002090",
      "lbl" : "immediately precedes",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "ends_at_start_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "meets"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000063"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002131",
      "lbl" : "overlaps",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x overlaps y if and only if there exists some z such that x has part z and z part of y"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002162",
      "lbl" : "in taxon",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed."
        },
        "comments" : [ "Connects a biological entity to its taxon of origin." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0001-9227-417X"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/17921072"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20973947"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002180",
      "lbl" : "has component",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:Componency"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002202",
      "lbl" : "develops from",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y"
        },
        "comments" : [ "This is the transitive form of the develops from relation" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0001-9114-8737"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-1980-3228"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002203",
      "lbl" : "develops into",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of develops from"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-7073-9172"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-1980-3228"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002211",
      "lbl" : "regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0001-7476-6306"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-3837-8864"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GO"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Regulation precludes parthood; the regulatory process may not be within the regulated process."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "regulates (processual)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
          "val" : "false"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002212",
      "lbl" : "negatively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "negatively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002213",
      "lbl" : "positively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "positively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002215",
      "lbl" : "capable of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. "
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "osteoclast SubClassOf 'capable of' some 'bone resorption'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has function realized in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/21208450"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002216",
      "lbl" : "capable of part of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has function in"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/reflexivity/"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002222",
      "lbl" : "temporally related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "comments" : [ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends."
        }, {
          "pred" : "http://purl.org/dc/terms/source",
          "val" : "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002233",
      "lbl" : "has input",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "consumes"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Has_input"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002254",
      "lbl" : "has developmental contribution from",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x has developmental contribution from y iff x has some part z such that z develops from y"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002255",
      "lbl" : "developmentally contributes to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of has developmental contribution from"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002258",
      "lbl" : "developmentally preceded by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p"
        },
        "comments" : [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "false"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002263",
      "lbl" : "acts upstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002264",
      "lbl" : "acts upstream of or within",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "affects"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Acts_upstream_of_or_within"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002286",
      "lbl" : "developmentally succeeded by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Inverse of developmentally preceded by"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002304",
      "lbl" : "causally upstream of, positive effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q."
        },
        "comments" : [ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Causally_upstream_of,_positive_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002305",
      "lbl" : "causally upstream of, negative effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Causally_upstream_of,_negative_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002314",
      "lbl" : "characteristic of part of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "inheres in part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/reflexivity/"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002320",
      "lbl" : "evolutionarily related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds via some environmental process"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002323",
      "lbl" : "mereotopologically related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A mereological relationship or a topological relationship"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002324",
      "lbl" : "developmentally related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between entities participating in some developmental process (GO:0032502)"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002327",
      "lbl" : "enables",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c enables p iff c is capable of p and c acts to execute p."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "a particular instances of akt-2 enables some instance of protein kinase activity"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "catalyzes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "executes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is catalyzing"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is executing"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Enables"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002328",
      "lbl" : "functionally related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002329",
      "lbl" : "part of structure that is capable of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "this relation holds between c and p when c is part of some c', and c' is capable of p."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "false"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002331",
      "lbl" : "involved in",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c involved_in p if and only if c enables some process p', and p' is part of p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "actively involved in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "enables part of"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Involved_in"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002333",
      "lbl" : "enabled by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of enables"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Enabled_by"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002334",
      "lbl" : "regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of regulates"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "regulated by (processual)"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002335",
      "lbl" : "negatively regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of negatively regulates"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002336",
      "lbl" : "positively regulated by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of positively regulates"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002352",
      "lbl" : "input of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of has input"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002384",
      "lbl" : "has developmental potential involving",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002385",
      "lbl" : "has potential to developmentally contribute to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002387",
      "lbl" : "has potential to develop into",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x has the potential to develop into y iff x develops into y or if x is capable of developing into y"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002388",
      "lbl" : "has potential to directly develop into",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002404",
      "lbl" : "causally downstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of upstream of"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002405",
      "lbl" : "immediately causally downstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002407",
      "lbl" : "indirectly positively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly activates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002579",
          "val" : "http://purl.obolibrary.org/obo/RO_0002213"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Indirectly_positively_regulates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002409",
      "lbl" : "indirectly negatively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly inhibits"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002579",
          "val" : "http://purl.obolibrary.org/obo/RO_0002212"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Indirectly_negatively_regulates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002410",
      "lbl" : "causally related to",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.",
          "xrefs" : [ "https://en.wikipedia.org/wiki/Causality" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002411",
      "lbl" : "causally upstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002412",
      "lbl" : "immediately causally upstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002418",
      "lbl" : "causally upstream of or within",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q."
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "affects"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "influences (processual)"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002427",
      "lbl" : "causally downstream of or within",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "inverse of causally upstream of or within"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002428",
      "lbl" : "involved in regulation of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' regulates some p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002429",
      "lbl" : "involved in positive regulation of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' positively regulates some p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002428"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002430",
      "lbl" : "involved in negative regulation of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002428"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002431",
      "lbl" : "involved in or involved in regulation of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "OWL does not allow defining object properties via a Union"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "involved in or reguates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002434",
      "lbl" : "interacts with",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two entities in which the processes executed by the two entities are causally connected."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "in pairwise interaction with"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Considering relabeling as 'pairwise interacts with'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        }, {
          "pred" : "http://www.w3.org/2004/02/skos/core#closeMatch",
          "val" : "http://purl.obolibrary.org/obo/MI_0914"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002436",
      "lbl" : "molecularly interacts with",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "binds"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "molecularly binds with"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ECO_0000353"
        }, {
          "pred" : "http://www.w3.org/2004/02/skos/core#closeMatch",
          "val" : "http://purl.obolibrary.org/obo/MI_0915"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002447",
      "lbl" : "phosphorylates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Axiomatization to GO to be added later"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002448",
      "lbl" : "directly regulates activity of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B."
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly controls"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-4639-4431"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002449",
      "lbl" : "directly negatively regulates activity of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B."
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly decreases activity of"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-4639-4431"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly inhibits"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002450",
      "lbl" : "directly positively regulates activity of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B."
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly increases activity of"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-4639-4431"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly activates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002464",
      "lbl" : "helper property (not for use in curation)",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002481",
      "lbl" : "is kinase activity",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002500",
      "lbl" : "causal agent in process",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a material entity and a process where the material entity has some causal role that influences the process"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002501",
      "lbl" : "causal relation between processes",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002502",
      "lbl" : "depends on",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000169"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002506",
      "lbl" : "causal relation between entities",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002559",
      "lbl" : "causally influenced by",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "causally influenced by (entity-centric)"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002563",
      "lbl" : "interaction relation helper property",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002564",
      "lbl" : "molecular interaction relation helper property",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002566",
      "lbl" : "causally influences",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-4639-4431"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "causally influences (entity-centric)"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002578",
      "lbl" : "directly regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p directly regulates q iff p is immediately causally upstream of q and p regulates q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly regulates (processual)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002584",
      "lbl" : "has part structure that is capable of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002595",
      "lbl" : "causal relation between material entity and a process",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002596",
      "lbl" : "capable of regulating",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a regulates p."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "pyrethroid -> growth"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002597",
      "lbl" : "capable of negatively regulating",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002598",
      "lbl" : "capable of positively regulating",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "renin -> arteriolar smooth muscle contraction"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002608",
      "lbl" : "process has causal agent",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Inverse of 'causal agent in process'"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002629",
      "lbl" : "directly positively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly positively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002578"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Directly_positively_regulates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002630",
      "lbl" : "directly negatively regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q."
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly negatively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002578"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Directly_negatively_regulates"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004031",
      "lbl" : "enables subfunction",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-01-25T23:20:13Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004032",
      "lbl" : "acts upstream of or within, positive effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002264"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-01-26T23:49:30Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Acts_upstream_of_or_within,_positive_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004033",
      "lbl" : "acts upstream of or within, negative effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002264"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-01-26T23:49:51Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Acts_upstream_of_or_within,_negative_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004034",
      "lbl" : "acts upstream of, positive effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002263"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-01-26T23:53:14Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Acts_upstream_of,_positive_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004035",
      "lbl" : "acts upstream of, negative effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative"
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002263"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-01-26T23:53:22Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Acts_upstream_of,_negative_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004046",
      "lbl" : "causally upstream of or within, negative effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002418"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-03-13T23:55:05Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004047",
      "lbl" : "causally upstream of or within, positive effect",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002418"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-03-13T23:55:19Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://wiki.geneontology.org/Causally_upstream_of_or_within,_positive_effect"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011002",
      "lbl" : "regulates activity of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0003-4639-4431"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0012011",
      "lbl" : "indirectly causally upstream of",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0003-1813-6857"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2022-09-26T06:07:17Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0012012",
      "lbl" : "indirectly regulates",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "https://orcid.org/0000-0003-1813-6857"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2022-09-26T06:08:01Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0017001",
      "lbl" : "device utilizes material",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y."
        },
        "synonyms" : [ {
          "pred" : "hasBroadSynonym",
          "val" : "utilizes"
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A diagnostic testing device utilizes a specimen."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "See github ticket https://github.com/oborel/obo-relations/issues/497"
        }, {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "https://orcid.org/0000-0001-9625-1899"
        }, {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "https://orcid.org/0000-0003-2620-0345"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2021-11-08T12:00:00Z"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0019000",
      "lbl" : "regulates characteristic",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "https://orcid.org/0000-0002-8688-6599"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0019001",
      "lbl" : "positively regulates characteristic",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "https://orcid.org/0000-0002-8688-6599"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0019002",
      "lbl" : "negatively regulates characteristic",
      "type" : "PROPERTY",
      "propertyType" : "OBJECT",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "https://orcid.org/0000-0002-8688-6599"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000002",
      "lbl" : "example to be eventually removed",
      "type" : "INDIVIDUAL",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "example to be eventually removed"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000120",
      "lbl" : "metadata complete",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "metadata complete"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000121",
      "lbl" : "organizational term",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "organizational term"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000122",
      "lbl" : "ready for release",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "ready for release"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000123",
      "lbl" : "metadata incomplete",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "metadata incomplete"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000124",
      "lbl" : "uncurated",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "uncurated"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000125",
      "lbl" : "pending final vetting",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "pending final vetting"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000423",
      "lbl" : "to be replaced with external ontology term",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "Terms with this status should eventually replaced with a term from another ontology."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "to be replaced with external ontology term"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Alan Ruttenberg"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "group:OBI"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000428",
      "lbl" : "requires discussion",
      "type" : "INDIVIDUAL",
      "meta" : {
        "definition" : {
          "val" : "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "requires discussion"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Alan Ruttenberg"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "group:OBI"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000111",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000112",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000114",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000116",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000117",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000118",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000119",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000232",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000233",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000424",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000589",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000600",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000700",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/OMO_0003003",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001900",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002161",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002175",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002259",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002575",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002579",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002581",
      "lbl" : "is a defining property chain axiom",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION",
      "meta" : {
        "definition" : {
          "val" : "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL"
        }
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002582",
      "lbl" : "is a defining property chain axiom where second argument is reflexive",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION",
      "meta" : {
        "definition" : {
          "val" : "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R."
        }
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004049",
      "type" : "PROPERTY",
      "propertyType" : "ANNOTATION"
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