Gene Tier aSHM QC Mean Variant Quality citekey PMID MutationEffect Mutation-PMID Effect-CiteKey Additional_Support ARID1A 1 loveGeneticLandscapeMutations2012 23143597 LOF 38458187 barisicARID1AOrchestratesSWI2024 giulino-rothTargetedGenomicSequencing2012 BACH2 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 LOF 26522720 hunterNFkBSubunitCRel2016 paneaWholeGenomeLandscape2019 BCL6 1 TRUE PASS 4 loveGeneticLandscapeMutations2012 30617194 LOF 12504096 masclePointMutationsBCL62003 grandeGenomewideDiscoverySomatic2019 BCL7A 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 LOF 32576963 balinas-gaviraFrequentMutationsAminoterminal2020 thomasGeneticSubgroupsInform2023 BMP7 1 paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023 CCND3 1 richterRecurrentMutationID32012 23143595 GOF 22885699 schmitzBurkittLymphomaPathogenesis2012 abateDistinctViralMutational2015 CHD8 1 grandeGenomewideDiscoverySomatic2019 36201743 paneaWholeGenomeLandscape2019 CREBBP 1 PASS 4 loveGeneticLandscapeMutations2012 23143597 LOF 33431788 huangCREBBPEP300Mutations2021 grandeGenomewideDiscoverySomatic2019 DDX3X 1 schmitzBurkittLymphomaPathogenesis2012 22885699 LOF 34437837 gongSequentialInverseDysregulation2021 abateDistinctViralMutational2015 EZH2 1 PASS 5 loveGeneticLandscapeMutations2012 23143597 FBXO11 1 richterRecurrentMutationID32012 23143595 LOF 22113614 duanFBXO11TargetsBCL62011 grandeGenomewideDiscoverySomatic2019 FOXO1 1 schmitzBurkittLymphomaPathogenesis2012 22885699 GOF 23460611 trinhAnalysisFOXO1Mutations grandeGenomewideDiscoverySomatic2019 GNA13 1 schmitzBurkittLymphomaPathogenesis2012 22885699 LOF 26616858 ohayreInactivatingMutationsGNA132016 loveGeneticLandscapeMutations2012 GNAI2 1 grandeGenomewideDiscoverySomatic2019 30617194 thomasGeneticSubgroupsInform2023 HIST1H1E 1 TRUE grandeGenomewideDiscoverySomatic2019 31558468 paneaWholeGenomeLandscape2019 HNRNPU 1 TRUE paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023 ID3 1 richterRecurrentMutationID32012 23143595 loveGeneticLandscapeMutations2012 KMT2D 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 26366712 zhangDisruptionKMT2DPerturbs2015 paneaWholeGenomeLandscape2019 MYC 1 TRUE johnstonCmycHypermutationBurkitt1992 1297477 GOF 38565249 freieGermlinePointMutation2024 loveGeneticLandscapeMutations2012 P2RY8 1 muppidiLossSignalingGa132014 25274307 LOF 25274307 muppidiLossSignalingGa132014 grandeGenomewideDiscoverySomatic2019 PCBP1 1 schmitzBurkittLymphomaPathogenesis2012 22885699 wagenerPCBP1GeneEncoding2015 PHF6 1 thomasGeneticSubgroupsInform2023 36201743 zhouSporadicEndemicBurkitt2019 PTEN 1 loveGeneticLandscapeMutations2012 23143597 LOF 23840064 pfeiferPTENLossDefines2013 paneaWholeGenomeLandscape2019 RFX7 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 30926791 weberPiggyBacTransposonTools2019 paneaWholeGenomeLandscape2019 RHOA 1 richterRecurrentMutationID32012 23143595 LOF 26616858 ohayreInactivatingMutationsGNA132016 grandeGenomewideDiscoverySomatic2019 SIN3A 1 grandeGenomewideDiscoverySomatic2019 30617194 paneaWholeGenomeLandscape2019 SMARCA4 1 richterRecurrentMutationID32012 23143595 LOF 33144586 fernandoFunctionalCharacterizationSMARCA42020 grandeGenomewideDiscoverySomatic2019 TCF3 1 schmitzBurkittLymphomaPathogenesis2012 22885699 GOF 22885699 schmitzBurkittLymphomaPathogenesis2012 abateDistinctViralMutational2015 TCL1A 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 thomasGeneticSubgroupsInform2023 TFAP4 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 34283887 toncUnexpectedSuppressionTumorigenesis2021 paneaWholeGenomeLandscape2019 TP53 1 wildaInactivationARFMDM2p53Pathway2004 14712292 LOF 12826609 katoUnderstandingFunctionstructureFunctionmutation2003 schmitzBurkittLymphomaPathogenesis2012 USP7 1 grandeGenomewideDiscoverySomatic2019 30617194 paneaWholeGenomeLandscape2019 WNK1 1 thomasGeneticSubgroupsInform2023 36201743 paneaWholeGenomeLandscape2019 IGLL5 1 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023 TBL1XR1 2 maSubtypespecificCooccurringGenetic2022 33792219 B2M 2 maSubtypespecificCooccurringGenetic2022 33792219 ADAMTS5 2 burkhardtClinicalRelevanceMolecular2022 35794096 ADNP 2 burkhardtClinicalRelevanceMolecular2022 35794096 AGO4 2 burkhardtClinicalRelevanceMolecular2022 35794096 ARHGEF1 2 muppidiLossSignalingGa132014 25274307 BCL2 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096 BTG1 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096 C16orf48 2 schmitzBurkittLymphomaPathogenesis2012 22885699 CARD11 2 maSubtypespecificCooccurringGenetic2022 33792219 CARD4 2 PASS 4 loveGeneticLandscapeMutations2012 23143597 CCNF 2 abateDistinctViralMutational2015 26468873 CD79A 2 burkhardtClinicalRelevanceMolecular2022 35794096 CDC27 2 maSubtypespecificCooccurringGenetic2022 33792219 CD83 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468 CDC73 2 PASS 3 loveGeneticLandscapeMutations2012 23143597 HIST1H1B 2 maSubtypespecificCooccurringGenetic2022 33792219 CDKN2A 2 grandeGenomewideDiscoverySomatic2019 30617194 CDKN2C 2 thomasGeneticSubgroupsInform2023 36201743 CHD4 2 burkhardtClinicalRelevanceMolecular2022 35794096 CPXM2 2 burkhardtClinicalRelevanceMolecular2022 35794096 CXCR4 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 DHCR7 2 schmitzBurkittLymphomaPathogenesis2012 22885699 E2F2 2 burkhardtClinicalRelevanceMolecular2022 35794096 EBF1 2 TRUE thomasGeneticSubgroupsInform2023 36201743 EDNRB 2 burkhardtClinicalRelevanceMolecular2022 35794096 EHD1 2 thomasGeneticSubgroupsInform2023 36201743 EIF4A1 2 paneaWholeGenomeLandscape2019 31558468 ELP2 2 schmitzBurkittLymphomaPathogenesis2012 22885699 EPPK1 2 paneaWholeGenomeLandscape2019 31558468 ERAP1 2 burkhardtClinicalRelevanceMolecular2022 35794096 EXOSC6 2 schmitzBurkittLymphomaPathogenesis2012 22885699 FLYWCH1 2 schmitzBurkittLymphomaPathogenesis2012 22885699 GGTLA4 2 PASS 4 loveGeneticLandscapeMutations2012 23143597 GTSE1 2 schmitzBurkittLymphomaPathogenesis2012 22885699 HIST1H3D 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468 HIST1H3I 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 HIST1H4J 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468 HLA-DQB1 2 burkhardtClinicalRelevanceMolecular2022 35794096 IKZF3 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468 IRF8 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 KANK2 2 schmitzBurkittLymphomaPathogenesis2012 22885699 KLHL26 2 burkhardtClinicalRelevanceMolecular2022 35794096 KMT2C 2 zhouSporadicEndemicBurkitt2019 31300419 MCL1 2 PASS 4 paneaWholeGenomeLandscape2019 31558468 MIR142 2 TRUE grandeGenomewideDiscoverySomatic2019 30617194 MKI67 2 schmitzBurkittLymphomaPathogenesis2012 22885699 MYO18A 2 schmitzBurkittLymphomaPathogenesis2012 22885699 NBEAL1 2 PASS 4 loveGeneticLandscapeMutations2012 23143597 NCOR2 2 schmitzBurkittLymphomaPathogenesis2012 22885699 NOA1 2 burkhardtClinicalRelevanceMolecular2022 35794096 P2RY2 2 PASS 4 loveGeneticLandscapeMutations2012 23143597 PDCD11 2 schmitzBurkittLymphomaPathogenesis2012 22885699 PIM1 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096 PLCG2 2 PASS 3 paneaWholeGenomeLandscape2019 31558468 TNFRSF14 2 maSubtypespecificCooccurringGenetic2022 33792219 PPP6R2 2 burkhardtClinicalRelevanceMolecular2022 35794096 PREX1 2 burkhardtClinicalRelevanceMolecular2022 35794096 RANBP6 2 PASS 5 loveGeneticLandscapeMutations2012 23143597 REV3L 2 burkhardtClinicalRelevanceMolecular2022 35794096 RNF144B 2 PASS 3 paneaWholeGenomeLandscape2019 31558468 RPL10 2 burkhardtClinicalRelevanceMolecular2022 35794096 S1PR2 2 TRUE muppidiLossSignalingGa132014 25274307 SAL3 2 burkhardtClinicalRelevanceMolecular2022 35794096 TET2 2 thomasGeneticSubgroupsInform2023 36201743 TOP2A 2 schmitzBurkittLymphomaPathogenesis2012 22885699 TTN 2 burkhardtClinicalRelevanceMolecular2022 35794096 VWA7 2 burkhardtClinicalRelevanceMolecular2022 35794096 WDR90 2 schmitzBurkittLymphomaPathogenesis2012 22885699 WHAMM 2 schmitzBurkittLymphomaPathogenesis2012 22885699 WNK2 2 PASS 4 paneaWholeGenomeLandscape2019 31558468 PRDM1 2 maSubtypespecificCooccurringGenetic2022 33792219 YY1AP1 2 schmitzBurkittLymphomaPathogenesis2012 22885699 ZAN 2 burkhardtClinicalRelevanceMolecular2022 35794096 ZBTB7A 2 burkhardtClinicalRelevanceMolecular2022 35794096 ZFP36L1 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 ZNF85 2 burkhardtClinicalRelevanceMolecular2022 35794096 ACAD9 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 ACE 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 ALPK2 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 ATP2C2 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 BRAF 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 BRD4 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 BTG2 3 TRUE FAIL 1 loveGeneticLandscapeMutations2012 31558468 C6orf27 3 FAIL Germline loveGeneticLandscapeMutations2012 23143597 CAD 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 CCT6B 3 FAIL Germline loveGeneticLandscapeMutations2012 23143597 CD79B 3 FAIL 2 paneaWholeGenomeLandscape2019 31558468 CDH17 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 COL4A2 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 CTCF 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 CYB5D1 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 CYP4F22 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 DLGAP1 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 DNMT1 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 DTX1 3 TRUE FAIL 1 loveGeneticLandscapeMutations2012 31558468 EIF2C4 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 EML2 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 ENTPD3 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 EPHB2 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 ETS1 3 TRUE FAIL 1 paneaWholeGenomeLandscape2019 31558468 FAM129B 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 FGFR3 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 FTCD 3 FAIL Germline loveGeneticLandscapeMutations2012 23143597 FZD3 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 GRIK5 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 HIST1H1C 3 TRUE FAIL 2 paneaWholeGenomeLandscape2019 31558468 HIST1H2AG 3 TRUE FAIL 2 paneaWholeGenomeLandscape2019 31558468 HIST1H2AM 3 TRUE FAIL 0 paneaWholeGenomeLandscape2019 31558468 HIST1H2BK 3 TRUE FAIL 1 paneaWholeGenomeLandscape2019 31558468 HIST1H3H 3 TRUE FAIL 0 paneaWholeGenomeLandscape2019 31558468 HIST1H3J 3 TRUE FAIL 0 paneaWholeGenomeLandscape2019 31558468 ICK 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 ITPR3 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 KCNK10 3 FAIL 2 paneaWholeGenomeLandscape2019 31558468 KIFC3 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 MAP3K6 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 MME 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 MTOR 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 MYH10 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 NOTCH1 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 NRXN2 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 PABPC4L 3 FAIL 2 paneaWholeGenomeLandscape2019 31558468 PC 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 PCDHA11 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 PDZRN3 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 PIK3R1 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 POLRMT 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 POR 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 PRSS22 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 PTPRN 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 PXDNL 3 FAIL 1 paneaWholeGenomeLandscape2019 31558468 RBP3 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 RET 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 SALL3 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 SAPS2 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 SBF1 3 FAIL 2 loveGeneticLandscapeMutations2012 23143597 SF3B1 3 FAIL 4 loveGeneticLandscapeMutations2012 23143597 SHANK1 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 SLC29A2 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 SNTB2 3 FAIL 2 paneaWholeGenomeLandscape2019 31558468 SYNGAP1 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 TBC1D9B 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 TIGD6 3 FAIL 1 loveGeneticLandscapeMutations2012 23143597 TPST2 3 FAIL 0 loveGeneticLandscapeMutations2012 23143597 WDR7 3 FAIL 2 paneaWholeGenomeLandscape2019 31558468 ZNF229 3 FAIL Germline loveGeneticLandscapeMutations2012 23143597