Neuro Behaviour Ontology
type: Ontology
version IRI: nbo.owl
description: An ontology of human and animal behaviours.
license: https://creativecommons.org/licenses/by/3.0/
treat-xrefs-as-equivalent: GO
version info: 2023-07-04

definition
type: AnnotationProperty

term replaced by
type: AnnotationProperty

is a defining property chain axiom
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL

is a defining property chain axiom where second argument is reflexive
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.

part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
IAO_0000111: is part of
IAO_0000112: my brain is part of my body (continuant parthood, two material entities)
IAO_0000112: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
IAO_0000112: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
IAO_0000116: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
IAO_0000118: part_of
RO_0001900: RO_0001901
RO_0040042: continuant
RO_0040042: occurrent
RO_0040042: independent continuant
RO_0040042: realizable
RO_0040042: quality
RO_0040042: specifically dependent continuant
RO_0040042: BFO_0000031
label: part_of

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
IAO_0000111: has part
IAO_0000112: my body has part my brain (continuant parthood, two material entities)
IAO_0000112: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
IAO_0000112: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
IAO_0000116: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
IAO_0000118: has_part
RO_0001900: RO_0001901
label: has_part

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000111: preceded by
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
IAO_0000116: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
IAO_0000118: is preceded by
IAO_0000118: preceded_by

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000111: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.

occurs in
type: ObjectProperty
inverse of: contains process
domain: occurrent
domain: process
range: independent continuant
property chain axiom: part of
IAO_0000111: occurs in
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
IAO_0000118: occurs_in
IAO_0000118: unfolds in
IAO_0000118: unfolds_in
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant

contains process
type: ObjectProperty
IAO_0000111: site of
definition: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
inverse of: has characteristic
type: FunctionalProperty
IAO_0000111: inheres in
IAO_0000112: this fragility is a characteristic of this vase
IAO_0000112: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
IAO_0000118: inheres_in
RO_0001900: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: specifically dependent continuant
range: PATO_0000001
IAO_0000111: bearer of
IAO_0000112: this apple is bearer of this red color
IAO_0000112: this vase is bearer of this fragility
definition: Inverse of characteristic_of
IAO_0000116: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
IAO_0000118: bearer_of
IAO_0000118: is bearer of
RO_0001900: RO_0001901

participates in
type: ObjectProperty
inverse of: has participant
domain: continuant
range: occurrent
IAO_0000111: participates in
IAO_0000112: this blood clot participates in this blood coagulation
IAO_0000112: this input material (or this output material) participates in this process
IAO_0000112: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
IAO_0000118: participates_in

has participant
type: ObjectProperty
domain: occurrent
domain: process
range: continuant
property chain axiom: has part
IAO_0000111: has participant
IAO_0000112: this blood coagulation has participant this blood clot
IAO_0000112: this investigation has participant this investigator
IAO_0000112: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
IAO_0000116: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
IAO_0000118: has_participant

function of
type: ObjectProperty
sub property of: characteristic of
inverse of: has function
domain: function
IAO_0000112: this catalysis function is a function of this enzyme
definition: a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
IAO_0000116: A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.
IAO_0000118: function_of
IAO_0000118: is function of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

quality of
type: ObjectProperty
sub property of: characteristic of
inverse of: has quality
IAO_0000112: this red color is a quality of this apple
definition: a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
IAO_0000116: A quality inheres in its bearer at all times for which the quality exists.
IAO_0000118: is quality of
IAO_0000118: quality_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
IAO_0000112: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
IAO_0000116: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
IAO_0000118: is role of
IAO_0000118: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has function
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: function
IAO_0000112: this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)
definition: a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
IAO_0000116: A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.
IAO_0000118: has_function

has quality
type: ObjectProperty
sub property of: has characteristic
range: quality
IAO_0000112: this apple has quality this red color
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
IAO_0000116: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
IAO_0000118: has_quality

has role
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: role
IAO_0000112: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
IAO_0000116: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
IAO_0000118: has_role

has disposition
type: ObjectProperty
sub property of: has characteristic
inverse of: disposition of
domain: independent continuant
range: disposition
definition: a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence

disposition of
type: ObjectProperty
sub property of: characteristic of
definition: inverse of has disposition
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

location of
type: ObjectProperty
inverse of: located in
type: TransitiveProperty
IAO_0000111: is location of
IAO_0000112: my head is the location of my brain
IAO_0000112: this cage is the location of this rat
definition: a relation between two independent continuants, the location and the target, in which the target is entirely within the location
IAO_0000116: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000118: location_of
RO_0001900: RO_0001901

contained in
type: ObjectProperty
inverse of: contains
domain: material entity
range: independent continuant
property chain axiom: located in
property chain axiom: part of
IAO_0000111: contained in
IAO_0000116: Containment is location not involving parthood, and arises only where some immaterial continuant is involved.
IAO_0000116: Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):
IAO_0000116: Intended meaning: domain: material entity range: spatial region or site (immaterial continuant)
IAO_0000118: contained_in
RO_0001900: RO_0001901

contains
type: ObjectProperty
IAO_0000111: contains
RO_0001900: RO_0001901

located in
type: ObjectProperty
type: TransitiveProperty
domain: independent continuant
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: independent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
property chain axiom: part of
IAO_0000111: located in
IAO_0000112: my brain is located in my head
IAO_0000112: this rat is located in this cage
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
IAO_0000116: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
IAO_0000116: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000118: located_in
RO_0001900: RO_0001901

Axiom
annotated source: located in
annotated property: domain
annotated target: independent continuant
IAO_0000116: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

Axiom
annotated source: located in
annotated property: range
annotated target: independent continuant
IAO_0000116: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

2D boundary of
type: ObjectProperty
sub property of: mereotopologically related to
inverse of: has 2D boundary
IAO_0000112: the surface of my skin is a 2D boundary of my body
definition: a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity
IAO_0000116: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
IAO_0000116: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
IAO_0000118: 2D_boundary_of
IAO_0000118: boundary of
IAO_0000118: is 2D boundary of
IAO_0000118: is boundary of
IAO_0000118: surface of
RO_0001900: RO_0001901

has 2D boundary
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: immaterial entity
IAO_0000112: my body has 2D boundary the surface of my skin
definition: a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity
IAO_0000116: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
IAO_0000116: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: has boundary
IAO_0000118: has_2D_boundary
RO_0001900: RO_0001901

innervated_by
type: ObjectProperty
inverse of: innervates
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

bounding layer of
type: ObjectProperty
sub property of: part of
domain: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002124
range: material entity
definition: X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000
IAO_0000117: https://orcid.org/0000-0002-7073-9172
comment: A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.

has regulatory component activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulated by
definition: A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.

has negative regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: negatively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.

has positive regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: positively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.

has component activity
type: ObjectProperty
sub property of: has component process
comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.

has component process
type: ObjectProperty
sub property of: has component
domain: process
range: process
definition: w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.

directly regulated by
type: ObjectProperty
sub property of: regulated by
inverse of: directly regulates

directly negatively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly negatively regulates

directly positively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly positively regulates

has effector activity
type: ObjectProperty
sub property of: has component activity
type: FunctionalProperty
comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.

before or simultaneous with
type: ObjectProperty
sub property of: temporally related to
IAO_0000117: David Osumi-Sutherland
IAO_0000118: <=
comment: Primitive instance level timing relation between events

simultaneous with
type: ObjectProperty
sub property of: before or simultaneous with
type: TransitiveProperty
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: David Osumi-Sutherland
comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2)

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
IAO_0000117: David Osumi-Sutherland
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
property chain axiom: starts with
property chain axiom: ends with
IAO_0000117: David Osumi-Sutherland
IAO_0000118: starts_at_end_of
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

immediately precedes
type: ObjectProperty
sub property of: precedes
property chain axiom: ends with
property chain axiom: starts with
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: David Osumi-Sutherland
IAO_0000118: ends_at_start_of
IAO_0000118: meets
RO_0002575: precedes
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
property chain axiom: part of
property chain axiom: has part
IAO_0000114: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
RO_0001900: RO_0001901

Axiom
annotated source: overlaps
annotated property: propertyChainAxiom
annotated target: has part
annotated target: part of
RO_0002582: true

innervates
type: ObjectProperty
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

continuous with
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
domain: independent continuant
range: independent continuant
IAO_0000114: IAO_0000125
definition: X continuous_with Y if and only if X and Y share a fiat boundary.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: connected to
IAO_0000232: The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)
RO_0001900: RO_0001901

only in taxon
type: ObjectProperty
sub property of: in taxon
IAO_0000112: lactation SubClassOf 'only in taxon' some 'Mammalia'
IAO_0000114: IAO_0000125
definition: x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
IAO_0000116: The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/17921072
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20973947

in taxon
type: ObjectProperty
sub property of: evolutionarily related to
property chain axiom: part of
property chain axiom: has part
property chain axiom: develops from
property chain axiom: capable of
property chain axiom: develops from part of
property chain axiom: has developmental contribution from
IAO_0000114: IAO_0000125
definition: x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
IAO_0000117: 0000-0001-9227-417X
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/17921072
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20973947
comment: Connects a biological entity to its taxon of origin.

spatially disjoint from
type: ObjectProperty
sub property of: mereotopologically related to
IAO_0000114: IAO_0000125
definition: A is spatially_disjoint_from B if and only if they have no parts in common
IAO_0000116: There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552
IAO_0000232: Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy
IAO_0000424: BFO_0000051 exactly 0 (BFO_0000050 some ?Y)
RO_0001900: RO_0001901

connected to
type: ObjectProperty
sub property of: mereotopologically related to
domain: Restriction
  on property: part of
  some values from: RO_0002577
range: Restriction
  on property: part of
  some values from: RO_0002577
property chain axiom:
  inverse of: connects
property chain axiom: connects
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552

connects
type: ObjectProperty
sub property of: mereotopologically related to
domain: independent continuant
range: Restriction
  on property: part of
  some values from: RO_0002577
IAO_0000112: The M8 connects Glasgow and Edinburgh
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552

attached to part of
type: ObjectProperty
sub property of: mereotopologically related to
sub property of: biomechanically related to
property chain axiom: attached to
property chain axiom: part of
definition: a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
IAO_0000589: attached to part of (anatomical structure to anatomical structure)

Axiom
annotated source: attached to part of
annotated property: propertyChainAxiom
annotated target: attached to
annotated target: part of
RO_0002582: true

supplies
type: ObjectProperty
sub property of: connected to
definition: Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.
IAO_0000116: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205

drains
type: ObjectProperty
sub property of: connected to
definition: Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.
IAO_0000116: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205

has component
type: ObjectProperty
sub property of: has part
IAO_0000114: IAO_0000125
definition: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
IAO_0000116: The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
IAO_0000232: For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
RO_0001900: RO_0001901

develops from
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: develops into
type: TransitiveProperty
domain: independent continuant
range: independent continuant
IAO_0000114: IAO_0000125
definition: x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
IAO_0000117: https://orcid.org/0000-0001-9114-8737
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
comment: This is the transitive form of the develops from relation

develops into
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to develop into
sub property of: has potential to directly develop into
type: TransitiveProperty
IAO_0000114: IAO_0000125
definition: inverse of develops from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228

directly develops from
type: ObjectProperty
sub property of: develops from
inverse of: directly develops into
IAO_0000114: IAO_0000125
definition: Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000119: FBbt
RO_0002575: develops from
comment: TODO - add child relations from DOS

directly develops into
type: ObjectProperty
sub property of: develops into
IAO_0000114: IAO_0000125
definition: inverse of directly develops from
IAO_0000118: developmental precursor of

regulates
type: ObjectProperty
sub property of: causally upstream of
inverse of: regulated by
type: TransitiveProperty
domain: process
range: process
property chain axiom: has effector activity
property chain axiom: ends with
property chain axiom: directly regulates
definition: p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
IAO_0000117: https://orcid.org/0000-0001-7476-6306
IAO_0000117: https://orcid.org/0000-0002-3837-8864
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000119: GO
IAO_0000232: Regulation precludes parthood; the regulatory process may not be within the regulated process.
IAO_0000589: regulates (processual)
IAO_0000600: false

negatively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, negative effect
inverse of: negatively regulated by
property chain axiom: ends with
definition: p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: negatively regulates (process to process)
RO_0004050: regulates

positively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, positive effect
inverse of: positively regulated by
type: TransitiveProperty
property chain axiom: negatively regulates
property chain axiom: ends with
definition: p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: positively regulates (process to process)
RO_0004049: regulates

capable of
type: ObjectProperty
sub property of: capable of part of
domain: independent continuant
range: process
IAO_0000112: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
IAO_0000112: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function realized in
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20123131
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/21208450
IAO_0000232: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function in

Axiom
annotated source: capable of part of
annotated property: propertyChainAxiom
annotated target: capable of
annotated target: part of
RO_0002582: true

surrounded by
type: ObjectProperty
sub property of: adjacent to
inverse of: surrounds
IAO_0000114: IAO_0000125
definition: x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0001900: RO_0001901

adjacent to
type: ObjectProperty
sub property of: spatially disjoint from
domain: independent continuant
range: independent continuant
IAO_0000112: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
IAO_0000112: The epidermis layer of a vertebrate is adjacent to the dermis.
IAO_0000112: The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.
IAO_0000112: The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.
IAO_0000114: IAO_0000125
definition: x adjacent to y if and only if x and y share a boundary.
IAO_0000116: This relation acts as a join point with BSPO
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0001900: RO_0001901

Axiom
annotated source: adjacent to
annotated property: IAO_0000112
annotated target: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.

surrounds
type: ObjectProperty
sub property of: adjacent to
IAO_0000114: IAO_0000125
definition: inverse of surrounded by
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0001900: RO_0001901

temporally related to
type: ObjectProperty
domain: occurrent
range: occurrent
IAO_0000114: IAO_0000125
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Allen's interval algebra
IAO_0000232: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

starts
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: starts with
IAO_0000114: IAO_0000125
definition: inverse of starts with
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: Chris Mungall
IAO_0000119: Allen

starts with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
IAO_0000112: Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor
IAO_0000114: IAO_0000125
definition: x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: Chris Mungall
IAO_0000118: started by

develops from part of
type: ObjectProperty
sub property of: develops from
property chain axiom: directly develops from
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

develops in
type: ObjectProperty
sub property of: developmentally preceded by
property chain axiom: directly develops from
property chain axiom: located in
IAO_0000114: IAO_0000125
definition: x develops_in y if x is located in y whilst x is developing
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: EHDAA2
IAO_0000119: Jonathan Bard, EHDAA2

ends
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: ends with
IAO_0000114: IAO_0000125
definition: inverse of ends with
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: Chris Mungall

ends with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
IAO_0000114: IAO_0000125
definition: x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: Chris Mungall
IAO_0000118: finished by

has start location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: starts with
property chain axiom: occurs in
IAO_0000114: IAO_0000125
definition: x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: starts with process that occurs in

has end location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: ends with
property chain axiom: occurs in
IAO_0000114: IAO_0000125
definition: x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: ends with process that occurs in

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: process
property chain axiom: starts with
IAO_0000114: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: consumes

has output
type: ObjectProperty
sub property of: has participant
inverse of: output of
property chain axiom: ends with
IAO_0000114: IAO_0000125
definition: p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: produces

has developmental contribution from
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally contributes to
property chain axiom: has part
property chain axiom: develops from
IAO_0000112: Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
IAO_0000114: IAO_0000125
definition: x has developmental contribution from y iff x has some part z such that z develops from y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

developmentally contributes to
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally contribute to
property chain axiom: develops into
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: inverse of has developmental contribution from
IAO_0000117: https://orcid.org/0000-0002-6601-2165

developmentally induced by
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally induces
IAO_0000114: IAO_0000125
definition: t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T
IAO_0000117: https://orcid.org/0000-0001-9114-8737
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: induced by
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205
IAO_0000119: Developmental Biology, Gilbert, 8th edition, figure 6.5(F)
IAO_0000119: GO:0001759
IAO_0000232: We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]

developmentally induces
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally induce
IAO_0000114: IAO_0000125
definition: Inverse of developmentally induced by
IAO_0000117: https://orcid.org/0000-0002-6601-2165

developmentally preceded by
type: ObjectProperty
sub property of: developmentally related to
inverse of: developmentally succeeded by
domain: continuant
range: continuant
IAO_0000114: IAO_0000125
definition: Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
IAO_0000116: false
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: In general you should not use this relation to make assertions - use one of the more specific relations below this one
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from

acts upstream of
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of
IAO_0000112: A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
definition: c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.

acts upstream of or within
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: enables
property chain axiom: causally upstream of or within
IAO_0000112: A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
definition: c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.

developmentally replaces
type: ObjectProperty
sub property of: developmentally preceded by
IAO_0000114: IAO_0000125
definition: x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else
IAO_0000116: This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: replaces

developmentally succeeded by
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000125
definition: Inverse of developmentally preceded by
IAO_0000117: https://orcid.org/0000-0002-6601-2165

part of developmental precursor of
type: ObjectProperty
sub property of: developmentally succeeded by
property chain axiom: part of
property chain axiom: directly develops into
IAO_0000112: 'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue
IAO_0000114: IAO_0000125
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally upstream of, positive effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, positive effect
definition: p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
RO_0004049: causally upstream of
comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y

causally upstream of, negative effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, negative effect
definition: p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
RO_0004050: causally upstream of

characteristic of part of
type: ObjectProperty
sub property of: depends on
property chain axiom: characteristic of
property chain axiom: part of
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
IAO_0000116: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: inheres in part of
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205
RO_0001900: RO_0001901

Axiom
annotated source: characteristic of part of
annotated property: propertyChainAxiom
annotated target: characteristic of
annotated target: part of
RO_0002582: true

evolutionarily related to
type: ObjectProperty
definition: A relationship that holds via some environmental process
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
RO_0001900: RO_0001901

developmentally related to
type: ObjectProperty
definition: A relationship that holds between entities participating in some developmental process (GO:0032502)
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development

enables
type: ObjectProperty
sub property of: capable of
inverse of: enabled by
property chain axiom: has part
property chain axiom: has component activity
IAO_0000112: a particular instances of akt-2 enables some instance of protein kinase activity
definition: c enables p iff c is capable of p and c acts to execute p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: catalyzes
IAO_0000118: executes
IAO_0000118: has
IAO_0000118: is catalyzing
IAO_0000118: is executing
IAO_0000232: This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This is a grouping relation that collects relations used for the purpose of connecting structure and function

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: false

Axiom
annotated source: part of structure that is capable of
annotated property: propertyChainAxiom
annotated target: part of
annotated target: capable of
is a defining property chain axiom: true

involved in
type: ObjectProperty
sub property of: participates in
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: part of
definition: c involved_in p if and only if c enables some process p', and p' is part of p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: actively involved in
IAO_0000118: enables part of

enabled by
type: ObjectProperty
sub property of: has participant
sub property of: functionally related to
definition: inverse of enables
IAO_0000117: https://orcid.org/0000-0002-6601-2165

regulated by
type: ObjectProperty
sub property of: causally downstream of or within
type: TransitiveProperty
domain: process
range: process
definition: inverse of regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000589: regulated by (processual)

negatively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of negatively regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165

positively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of positively regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
IAO_0000112: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.
IAO_0000118: is member of
IAO_0000118: member part of
IAO_0000119: SIO
RO_0001900: RO_0001901

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
IAO_0000119: SIO
RO_0001900: RO_0001901

input of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has input
IAO_0000117: https://orcid.org/0000-0002-6601-2165

output of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has output
IAO_0000117: https://orcid.org/0000-0002-6601-2165

attached to
type: ObjectProperty
sub property of: connected to
sub property of: attached to part of
type: SymmetricProperty
definition: a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000589: attached to (anatomical structure to anatomical structure)

has muscle origin
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
definition: m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Wikipedia:Insertion_(anatomy)

has muscle insertion
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
definition: m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Wikipedia:Insertion_(anatomy)

in branching relationship with
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: material entity
IAO_0000114: IAO_0000428
definition: A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships
IAO_0000232: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)
RO_0004036: part of

tributary of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
IAO_0000112: Deschutes River tributary_of Columbia River
IAO_0000112: inferior epigastric vein tributary_of external iliac vein
IAO_0000114: IAO_0000428
definition: x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: drains into
IAO_0000118: drains to
IAO_0000118: tributary channel of
IAO_0000119: http://en.wikipedia.org/wiki/Tributary
IAO_0000119: http://www.medindia.net/glossary/venous_tributary.htm
IAO_0000232: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)

spatially coextensive with
type: ObjectProperty
sub property of: overlaps
property chain axiom: located in
property chain axiom:
  inverse of: located in
IAO_0000112: A lump of clay and a statue
definition: x spatially_coextensive_with y if and inly if x and y have the same location
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This relation is added for formal completeness. It is unlikely to be used in many practical scenarios

branching part of
type: ObjectProperty
sub property of: part of
sub property of: in branching relationship with
inverse of: has branching part
range: Restriction
  on property: has characteristic
  some values from: PATO_0000402
IAO_0000112: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S
definition: x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has developmental potential involving
type: ObjectProperty
sub property of: developmentally related to
IAO_0000114: IAO_0000428
definition: x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to developmentally contribute to
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to developmentally induce
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to develop into
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has the potential to develop into y iff x develops into y or if x is capable of developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to directly develop into
type: ObjectProperty
sub property of: has potential to develop into
IAO_0000114: IAO_0000428
definition: x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally downstream of
type: ObjectProperty
sub property of: preceded by
sub property of: causally downstream of or within
inverse of: causally upstream of
IAO_0000114: IAO_0000428
definition: inverse of upstream of
IAO_0000117: https://orcid.org/0000-0002-6601-2165

immediately causally downstream of
type: ObjectProperty
sub property of: immediately preceded by
sub property of: causally downstream of
inverse of: immediately causally upstream of
IAO_0000114: IAO_0000428
IAO_0000117: https://orcid.org/0000-0002-6601-2165

indirectly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly positively regulates
property chain axiom: indirectly negatively regulates
definition: p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: indirectly activates
RO_0002579: positively regulates

indirectly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly negatively regulates
definition: p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: indirectly inhibits
RO_0002579: negatively regulates

causally related to
type: ObjectProperty
IAO_0000116: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

causally upstream of
type: ObjectProperty
sub property of: precedes
sub property of: causally upstream of or within
type: TransitiveProperty
definition: p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

immediately causally upstream of
type: ObjectProperty
sub property of: immediately precedes
sub property of: causally upstream of
definition: p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0002575: causally upstream of

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
IAO_0000116: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: influences (processual)

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations

involved in regulation of
type: ObjectProperty
sub property of: acts upstream of
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

involved in positive regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: positively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' positively regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0004049: involved in regulation of

involved in negative regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: negatively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0004050: involved in regulation of

involved in or involved in regulation of
type: ObjectProperty
sub property of: acts upstream of or within
sub property of: functionally related to
sub property of: causal agent in process
definition: c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
IAO_0000116: OWL does not allow defining object properties via a Union
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: involved in or reguates

is active in
type: ObjectProperty
sub property of: overlaps
sub property of: functionally related to
property chain axiom: enables
property chain axiom: occurs in
IAO_0000112: A protein that enables activity in a cytosol.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: executes activity in

Axiom
annotated source: is active in
annotated property: propertyChainAxiom
annotated target: enables
annotated target: occurs in
is a defining property chain axiom: true

contributes to morphology of
type: ObjectProperty
sub property of: overlaps
definition: p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

interacts with
type: ObjectProperty
type: SymmetricProperty
domain: material entity
range: material entity
definition: A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
IAO_0000116: This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
IAO_0000116: Considering relabeling as 'pairwise interacts with'
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.

molecularly interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
definition: An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: binds
IAO_0000118: molecularly binds with

phosphorylates
type: ObjectProperty
sub property of: molecularly interacts with
IAO_0000116: Axiomatization to GO to be added later
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.

directly regulates activity of
type: ObjectProperty
sub property of: molecularly interacts with
sub property of: regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431

directly negatively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly negatively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000118: directly inhibits

directly positively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly positively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000118: directly activates

helper property (not for use in curation)
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.

composed primarily of
type: ObjectProperty
sub property of: has part
domain: material entity
range: material entity
IAO_0000112: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552
RO_0001900: RO_0001901

has part that occurs in
type: ObjectProperty
domain: occurrent
range: independent continuant
property chain axiom: has part
property chain axiom: occurs in
definition: p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

Axiom
annotated source: has part that occurs in
annotated property: propertyChainAxiom
annotated target: has part
annotated target: occurs in
is a defining property chain axiom: true

is kinase activity
type: ObjectProperty
sub property of: molecular interaction relation helper property
IAO_0000117: https://orcid.org/0000-0002-6601-2165

relation between physical entity and a process or stage
type: ObjectProperty
domain: independent continuant
range: occurrent
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.

existence starts during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence starts during or after
property chain axiom: part of
definition: x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

existence starts with
type: ObjectProperty
sub property of: existence starts during
definition: x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

existence overlaps
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
definition: x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence starts and ends during
type: ObjectProperty
sub property of: existence starts during
sub property of: existence ends during
definition: x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence ends during or before
property chain axiom: part of
definition: x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends with
type: ObjectProperty
sub property of: existence ends during
definition: x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

transformation of
type: ObjectProperty
sub property of: develops from
type: TransitiveProperty
definition: x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships
IAO_0000117: https://orcid.org/0000-0002-6601-2165

immediate transformation of
type: ObjectProperty
sub property of: directly develops from
sub property of: transformation of
definition: x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0002575: transformation of

existence starts during or after
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally preceded by
property chain axiom: preceded by
property chain axiom: simultaneous with
definition: x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during or before
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally succeeded by
property chain axiom: precedes
property chain axiom: simultaneous with
definition: x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
IAO_0000119: causal-relations

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: occurrent
range: occurrent
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

depends on
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165

towards
type: ObjectProperty
sub property of: depends on
definition: q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2
IAO_0000116: This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205

causal relation between entities
type: ObjectProperty
sub property of: causally related to
domain: continuant
range: continuant
IAO_0000116: The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

has skeleton
type: ObjectProperty
sub property of: has part
inverse of: skeleton of
type: AsymmetricProperty
type: IrreflexiveProperty
IAO_0000112: Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'
definition: A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has supporting framework
IAO_0000232: The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell).

causally influenced by
type: ObjectProperty
sub property of: causal relation between entities
inverse of: causally influences
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: causally influenced by (entity-centric)

interaction relation helper property
type: ObjectProperty
sub property of: helper property (not for use in curation)
IAO_0000117: https://orcid.org/0000-0002-6601-2165

molecular interaction relation helper property
type: ObjectProperty
sub property of: interaction relation helper property
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally influences
type: ObjectProperty
sub property of: causal relation between entities
domain: continuant
range: continuant
property chain axiom: enables
property chain axiom: causally upstream of
property chain axiom: has input
property chain axiom: enabled by
definition: The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000119: causal-relations
IAO_0000589: causally influences (entity-centric)

biomechanically related to
type: ObjectProperty
sub property of: functionally related to
definition: A relation that holds between elements of a musculoskeletal system or its analogs.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.

has muscle antagonist
type: ObjectProperty
sub property of: biomechanically related to
definition: m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Wikipedia:Antagonist_(muscle)

has branching part
type: ObjectProperty
sub property of: has part
sub property of: in branching relationship with
type: TransitiveProperty
definition: inverse of branching part of
IAO_0000117: https://orcid.org/0000-0002-6601-2165

conduit for
type: ObjectProperty
sub property of: overlaps
domain: material entity
range: material entity
definition: x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: UBERON:cjm
IAO_0000232: This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through.

lumen of
type: ObjectProperty
sub property of: part of
range: material entity
definition: x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: GOC:cjm

luminal space of
type: ObjectProperty
sub property of: lumen of
domain: immaterial entity
definition: s is luminal space of x iff s is lumen_of x and s is an immaterial entity
IAO_0000117: https://orcid.org/0000-0002-6601-2165

skeleton of
type: ObjectProperty
sub property of: part of
definition: inverse of has skeleton
IAO_0000117: https://orcid.org/0000-0002-6601-2165

directly regulates
type: ObjectProperty
sub property of: regulates
sub property of: immediately causally upstream of
definition: p directly regulates q iff p is immediately causally upstream of q and p regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: directly regulates (processual)
RO_0002575: regulates

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
IAO_0000112: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: material entity
range: process
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
IAO_0000116: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations

capable of regulating
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: regulates
IAO_0000112: pyrethroid -> growth
definition: Holds between c and p if and only if c is capable of some activity a, and a regulates p.
IAO_0000119: causal-relations

capable of negatively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: negatively regulates
definition: Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
IAO_0000119: causal-relations

capable of positively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: positively regulates
IAO_0000112: renin -> arteriolar smooth muscle contraction
definition: Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
IAO_0000119: causal-relations

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
IAO_0000119: causal-relations

directly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: directly regulates
definition: p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
IAO_0000119: causal-relations
IAO_0000589: directly positively regulates (process to process)
RO_0004049: directly regulates

directly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: directly regulates
definition: p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
IAO_0000119: causal-relations
IAO_0000589: directly negatively regulates (process to process)
RO_0004050: directly regulates

produces
type: ObjectProperty
inverse of: produced by
domain: material entity
range: material entity
property chain axiom:
  inverse of: occurs in
property chain axiom: has output
IAO_0000114: IAO_0000125
definition: a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
IAO_0000117: https://orcid.org/0000-0001-9114-8737
comment: Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.

produced by
type: ObjectProperty
domain: material entity
range: material entity
IAO_0000114: IAO_0000125
definition: a produced_by b iff some process that occurs_in b has_output a.
IAO_0000117: https://orcid.org/0000-0001-9114-8737

enables subfunction
type: ObjectProperty
sub property of: functionally related to
property chain axiom: enables
property chain axiom: has part
definition: Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.

acts upstream of or within, positive effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, positive effect
RO_0004049: acts upstream of or within

acts upstream of or within, negative effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, negative effect
RO_0004050: acts upstream of or within

acts upstream of, positive effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, positive effect
property chain axiom: enables
property chain axiom: causally upstream of, positive effect
definition: c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
RO_0004049: acts upstream of

acts upstream of, negative effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, negative effect
property chain axiom: enables
property chain axiom: causally upstream of, negative effect
definition: c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
RO_0004050: acts upstream of

causally upstream of or within, negative effect
type: ObjectProperty
sub property of: causally upstream of or within
RO_0004050: causally upstream of or within

causally upstream of or within, positive effect
type: ObjectProperty
sub property of: causally upstream of or within
RO_0004049: causally upstream of or within

regulates activity of
type: ObjectProperty
sub property of: causally influences
domain: material entity
range: material entity
definition: The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0003-4639-4431

indirectly causally upstream of
type: ObjectProperty
sub property of: causally upstream of
definition: p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.

indirectly regulates
type: ObjectProperty
sub property of: regulates
sub property of: indirectly causally upstream of
definition: p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.

different in magnitude relative to
type: ObjectProperty
domain: PATO_0000001
range: PATO_0000001

increased in magnitude relative to
type: ObjectProperty
sub property of: different in magnitude relative to
domain: PATO_0000001
range: PATO_0000001
comment: This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.

decreased in magnitude relative to
type: ObjectProperty
sub property of: different in magnitude relative to
domain: PATO_0000001
range: PATO_0000001
comment: This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.

has cross section
type: ObjectProperty
comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.

reciprocal of
type: ObjectProperty
comment: There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality.

device utilizes material
type: ObjectProperty
property chain axiom: capable of
property chain axiom: has input
IAO_0000112: A diagnostic testing device utilizes a specimen.
definition: X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
IAO_0000117: https://orcid.org/0000-0001-9625-1899
IAO_0000117: https://orcid.org/0000-0003-2620-0345
IAO_0000232: A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.
IAO_0000232: See github ticket https://github.com/oborel/obo-relations/issues/497

regulates characteristic
type: ObjectProperty
sub property of: causally related to
domain: process
range: PATO_0000001
property chain axiom: regulates
definition: A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.

positively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.

negatively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: negatively regulates
property chain axiom: positively regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.

by_means
type: ObjectProperty

has-input
type: ObjectProperty

has_participant
type: ObjectProperty

in_response_to
type: ObjectProperty

is_about
type: ObjectProperty

qualifier
type: ObjectProperty

has number of atomic nuclei
type: DatatypeProperty
domain: material entity
range: nonNegativeInteger

entity
type: Class
BFO_0000179: entity
BFO_0000180: Entity
IAO_0000112: Julius Caesar
IAO_0000112: Verdi’s Requiem
IAO_0000112: the Second World War
IAO_0000112: your body mass index
IAO_0000116: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
IAO_0000116: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
IAO_0000600: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

Axiom
annotated source: entity
annotated property: IAO_0000116
annotated target: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000004
comment: per discussion with Barry Smith

Axiom
annotated source: entity
annotated property: IAO_0000600
annotated target: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/001-001

continuant
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: continuant
disjoint with: occurrent
disjoint with: Restriction
  on property: part of
  some values from: occurrent
BFO_0000179: continuant
BFO_0000180: Continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
IAO_0000116: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
IAO_0000116: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
IAO_0000600: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
IAO_0000601: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
IAO_0000601: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
IAO_0000601: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
IAO_0000602: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
IAO_0000602: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
IAO_0000602: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
IAO_0000602: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

Axiom
annotated source: continuant
annotated property: IAO_0000116
annotated target: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000007

Axiom
annotated source: continuant
annotated property: IAO_0000600
annotated target: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/011-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/011-002

occurrent
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: occurrent
disjoint with: Restriction
  on property: part of
  some values from: continuant
BFO_0000179: occurrent
BFO_0000180: Occurrent
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
IAO_0000116: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
IAO_0000116: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
IAO_0000116: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
IAO_0000116: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
IAO_0000600: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
IAO_0000601: Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
IAO_0000601: b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
IAO_0000602: (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
IAO_0000602: (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]

Axiom
annotated source: occurrent
annotated property: IAO_0000116
annotated target: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000006
comment: per discussion with Barry Smith

Axiom
annotated source: occurrent
annotated property: IAO_0000116
annotated target: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000012

Axiom
annotated source: occurrent
annotated property: IAO_0000600
annotated target: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/077-002

Axiom
annotated source: occurrent
annotated property: IAO_0000601
annotated target: Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: IAO_0000601
annotated target: b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/079-001

Axiom
annotated source: occurrent
annotated property: IAO_0000602
annotated target: (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: IAO_0000602
annotated target: (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/079-001

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: independent continuant
disjoint with: specifically dependent continuant
BFO_0000179: ic
BFO_0000180: IndependentContinuant
IAO_0000112: a chair
IAO_0000112: a heart
IAO_0000112: a leg
IAO_0000112: a molecule
IAO_0000112: a spatial region
IAO_0000112: an atom
IAO_0000112: an orchestra.
IAO_0000112: an organism
IAO_0000112: the bottom right portion of a human torso
IAO_0000112: the interior of your mouth
definition: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
IAO_0000601: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
IAO_0000601: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
IAO_0000602: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
IAO_0000602: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
IAO_0000602: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]

Axiom
annotated source: independent continuant
annotated property: definition
annotated target: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/017-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000601
annotated target: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: IAO_0000601
annotated target: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/017-002

spatial region
type: Class
subclass of: immaterial entity
BFO_0000179: s-region
BFO_0000180: SpatialRegion
IAO_0000116: BFO 2 Reference: Spatial regions do not participate in processes.
IAO_0000116: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
IAO_0000600: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
IAO_0000601: All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
IAO_0000602: (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
IAO_0000602: (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]

Axiom
annotated source: spatial region
annotated property: IAO_0000116
annotated target: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000002
comment: per discussion with Barry Smith

Axiom
annotated source: spatial region
annotated property: IAO_0000600
annotated target: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/035-001

Axiom
annotated source: spatial region
annotated property: IAO_0000601
annotated target: All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: IAO_0000602
annotated target: (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: IAO_0000602
annotated target: (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/035-001

process
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: part of
  all values from: process
BFO_0000179: process
BFO_0000180: Process
IAO_0000112: a process of cell-division, \ a beating of the heart
IAO_0000112: a process of meiosis
IAO_0000112: a process of sleeping
IAO_0000112: the course of a disease
IAO_0000112: the flight of a bird
IAO_0000112: the life of an organism
IAO_0000112: your process of aging.
definition: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
IAO_0000116: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
IAO_0000602: (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]

Axiom
annotated source: process
annotated property: definition
annotated target: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/083-003

Axiom
annotated source: process
annotated property: IAO_0000602
annotated target: (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/083-003

disposition
type: Class
subclass of: realizable
disjoint with: role
BFO_0000179: disposition
BFO_0000180: Disposition
IAO_0000112: an atom of element X has the disposition to decay to an atom of element Y
IAO_0000112: certain people have a predisposition to colon cancer
IAO_0000112: children are innately disposed to categorize objects in certain ways.
IAO_0000112: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
IAO_0000116: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
IAO_0000600: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
IAO_0000601: If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
IAO_0000602: (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
IAO_0000602: (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]

Axiom
annotated source: disposition
annotated property: IAO_0000600
annotated target: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/062-002

Axiom
annotated source: disposition
annotated property: IAO_0000601
annotated target: If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: IAO_0000602
annotated target: (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: IAO_0000602
annotated target: (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/062-002

realizable
type: Class
subclass of: specifically dependent continuant
subclass of: PATO_0000001
subclass of: Restriction
  on property: part of
  all values from: realizable
disjoint with: quality
BFO_0000179: realizable
BFO_0000180: RealizableEntity
IAO_0000112: the disposition of this piece of metal to conduct electricity.
IAO_0000112: the disposition of your blood to coagulate
IAO_0000112: the function of your reproductive organs
IAO_0000112: the role of being a doctor
IAO_0000112: the role of this boundary to delineate where Utah and Colorado meet
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
IAO_0000600: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
IAO_0000601: All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
IAO_0000602: (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
IAO_0000602: (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
label: realizable entity

Axiom
annotated source: realizable
annotated property: IAO_0000600
annotated target: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/058-002

Axiom
annotated source: realizable
annotated property: IAO_0000601
annotated target: All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable
annotated property: IAO_0000602
annotated target: (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable
annotated property: IAO_0000602
annotated target: (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/058-002

quality
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of
  all values from: quality
BFO_0000179: quality
BFO_0000180: Quality
IAO_0000112: the ambient temperature of this portion of air
IAO_0000112: the color of a tomato
IAO_0000112: the length of the circumference of your waist
IAO_0000112: the mass of this piece of gold.
IAO_0000112: the shape of your nose
IAO_0000112: the shape of your nostril
IAO_0000600: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
IAO_0000601: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
IAO_0000602: (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
IAO_0000602: (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]

Axiom
annotated source: quality
annotated property: IAO_0000600
annotated target: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: IAO_0000601
annotated target: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/105-001

Axiom
annotated source: quality
annotated property: IAO_0000602
annotated target: (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: IAO_0000602
annotated target: (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/105-001

specifically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: specifically dependent continuant
BFO_0000179: sdc
BFO_0000180: SpecificallyDependentContinuant
IAO_0000112: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
IAO_0000112: of one-sided specifically dependent continuants: the mass of this tomato
IAO_0000112: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
IAO_0000112: the disposition of this fish to decay
IAO_0000112: the function of this heart: to pump blood
IAO_0000112: the mutual dependence of proton donors and acceptors in chemical reactions [79
IAO_0000112: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
IAO_0000112: the pink color of a medium rare piece of grilled filet mignon at its center
IAO_0000112: the role of being a doctor
IAO_0000112: the shape of this hole.
IAO_0000112: the smell of this portion of mozzarella
definition: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
IAO_0000116: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
IAO_0000602: (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]

Axiom
annotated source: specifically dependent continuant
annotated property: definition
annotated target: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/050-003

Axiom
annotated source: specifically dependent continuant
annotated property: IAO_0000116
annotated target: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000005
comment: per discussion with Barry Smith

Axiom
annotated source: specifically dependent continuant
annotated property: IAO_0000602
annotated target: (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/050-003

role
type: Class
subclass of: realizable
BFO_0000179: role
BFO_0000180: Role
IAO_0000112: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
IAO_0000112: the priest role
IAO_0000112: the role of a boundary to demarcate two neighboring administrative territories
IAO_0000112: the role of a building in serving as a military target
IAO_0000112: the role of a stone in marking a property boundary
IAO_0000112: the role of subject in a clinical trial
IAO_0000112: the student role
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
IAO_0000116: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
IAO_0000600: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
IAO_0000602: (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]

Axiom
annotated source: role
annotated property: IAO_0000600
annotated target: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/061-001

Axiom
annotated source: role
annotated property: IAO_0000602
annotated target: (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/061-001

function
type: Class
subclass of: disposition
BFO_0000179: function
BFO_0000180: Function
IAO_0000112: the function of a hammer to drive in nails
IAO_0000112: the function of a heart pacemaker to regulate the beating of a heart through electricity
IAO_0000112: the function of amylase in saliva to break down starch into sugar
IAO_0000116: BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.
IAO_0000600: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
IAO_0000602: (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]

Axiom
annotated source: function
annotated property: IAO_0000600
annotated target: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/064-001

Axiom
annotated source: function
annotated property: IAO_0000602
annotated target: (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/064-001

material entity
type: Class
subclass of: independent continuant
disjoint with: immaterial entity
disjoint with: Restriction
  on property: part of
  some values from: immaterial entity
BFO_0000179: material
BFO_0000180: MaterialEntity
IAO_0000112: a flame
IAO_0000112: a forest fire
IAO_0000112: a human being
IAO_0000112: a hurricane
IAO_0000112: a photon
IAO_0000112: a puff of smoke
IAO_0000112: a sea wave
IAO_0000112: a tornado
IAO_0000112: an aggregate of human beings.
IAO_0000112: an energy wave
IAO_0000112: an epidemic
IAO_0000112: the undetached arm of a human being
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
IAO_0000116: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
IAO_0000116: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
IAO_0000116: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
IAO_0000600: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
IAO_0000601: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
IAO_0000601: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
IAO_0000602: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
IAO_0000602: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
IAO_0000602: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

Axiom
annotated source: material entity
annotated property: IAO_0000600
annotated target: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: IAO_0000601
annotated target: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/020-002

Axiom
annotated source: material entity
annotated property: IAO_0000601
annotated target: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/020-002

immaterial entity
type: Class
subclass of: independent continuant
disjoint with: Restriction
  on property: has part
  some values from: material entity
BFO_0000179: immaterial
BFO_0000180: ImmaterialEntity
IAO_0000116: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10

electron
type: Class
subclass of: lepton
subclass of: molecular entity
subclass of: Restriction
  on property: has number of atomic nuclei
  has value: 0
definition: Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
charge: -1
mass: 0.000548579903
monoisotopicmass: 0.0
label: nucleic acid polymer

Mycoplasma genitalium metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.

dicarboxylic acids and O-substituted derivatives
type: Class
subclass of: carbonyl compound
definition: A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.

hyaluronate
type: Class
subclass of: polyanionic polymer
subclass of: carbohydrate acid derivative anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hyaluronic acid
definition: A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3.
charge: -1
formula: (C14H20NO11)n.H2O

volatile organic compound
type: Class
subclass of: organic molecule
definition: Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa.

tertiary ammonium ion
type: Class
subclass of: organic cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tertiary amino compound
definition: An organic cation obtained by protonation of the amino group of any tertiary amino compound.
charge: +1
formula: HNR3
mass: 15.015
monoisotopicmass: 15.01090
smiles: [NH+](*)(*)*

3-(1-methylpyrrolidin-2-yl)pyridine
type: Class
subclass of: pyridine alkaloid
subclass of: pyrrolidine alkaloid
subclass of: N-alkylpyrrolidine
definition: An N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2.
charge: 0
formula: C10H14N2
inchi: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3
inchikey: SNICXCGAKADSCV-UHFFFAOYSA-N
mass: 162.232
monoisotopicmass: 162.11570
smiles: C=1C=C(C2N(CCC2)C)C=NC1

inorganic acid
type: Class
subclass of: Bronsted acid
definition: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.

gas molecular entity
type: Class
subclass of: main group molecular entity
definition: Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).

carbamate
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbamic acid
charge: -1
formula: CH2NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-M
mass: 60.03212
monoisotopicmass: 60.00910
smiles: NC([O-])=O

24G7 epitope
type: Class
subclass of: independent continuant
subclass of: group
subclass of: Restriction
  on property: has role
  some values from: epitope
definition: An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22.
charge: 0
formula: C7H6N2O
mass: 134.136
monoisotopicmass: 134.04801
smiles: C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*

acceptor
type: Class
subclass of: chemical role
definition: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.

water
type: Class
subclass of: independent continuant
subclass of: oxygen hydride
subclass of: mononuclear parent hydride
subclass of: inorganic hydroxy compound
subclass of: Restriction
  on property: has role
  some values from: amphiprotic solvent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: greenhouse gas
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydroxide
subclass of: Restriction
  on property: is conjugate base of
  some values from: oxonium
definition: An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms
charge: 0
formula: H2O
inchi: InChI=1S/H2O/h1H2
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-N
mass: 18.01530
monoisotopicmass: 18.01056
smiles: [H]O[H]

primary alcohol
type: Class
subclass of: alcohol
definition: A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
charge: 0
formula: CH3OR
mass: 31.034
monoisotopicmass: 31.01839
smiles: *C(O)([H])[H]

polypeptide
type: Class
subclass of: peptide
subclass of: macromolecule
definition: A peptide containing ten or more amino acid residues.
formula: C4H6N2O3R2(C2H2NOR)n

ammonia
type: Class
subclass of: independent continuant
subclass of: gas molecular entity
subclass of: azane
subclass of: mononuclear parent hydride
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: nucleophilic reagent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: EC 3.5.1.4 (amidase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: refrigerant
subclass of: Restriction
  on property: is conjugate acid of
  some values from: azanide
subclass of: Restriction
  on property: is conjugate base of
  some values from: ammonium
definition: An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
charge: 0
formula: H3N
inchi: InChI=1S/H3N/h1H3
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-N
mass: 17.03056
monoisotopicmass: 17.02655
smiles: [H]N([H])[H]

sulfate
type: Class
subclass of: independent continuant
subclass of: sulfur oxoanion
subclass of: sulfur oxide
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogensulfate
definition: A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid.
charge: -2
formula: O4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-L
mass: 96.06360
monoisotopicmass: 95.95283
smiles: [O-]S([O-])(=O)=O

hydroxide
type: Class
subclass of: independent continuant
subclass of: oxygen hydride
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: water
charge: -1
formula: HO
inchi: InChI=1S/H2O/h1H2/p-1
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-M
mass: 17.00734
monoisotopicmass: 17.00329
smiles: [O-][H]

ethanol
type: Class
subclass of: independent continuant
subclass of: volatile organic compound
subclass of: ethanols
subclass of: alkyl alcohol
subclass of: Restriction
  on property: has role
  some values from: central nervous system depressant
subclass of: Restriction
  on property: has role
  some values from: antiseptic drug
subclass of: Restriction
  on property: has role
  some values from: disinfectant
subclass of: Restriction
  on property: has role
  some values from: polar solvent
subclass of: Restriction
  on property: has role
  some values from: teratogenic agent
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: NMDA receptor antagonist
subclass of: Restriction
  on property: has role
  some values from: protein kinase C agonist
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: ethoxide
definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
charge: 0
formula: C2H6O
inchi: InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
inchikey: LFQSCWFLJHTTHZ-UHFFFAOYSA-N
mass: 46.06844
monoisotopicmass: 46.04186
smiles: CCO

hyaluronic acid
type: Class
subclass of: independent continuant
subclass of: mucopolysaccharide
subclass of: exopolysaccharide
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hyaluronate
definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.
charge: 0
formula: (C14H21NO12)n

protein polypeptide chain
type: Class
subclass of: polypeptide
subclass of: Restriction
  on property: has part
  some values from: proteinogenic amino-acid residue
definition: A naturally occurring polypeptide synthesized at the ribosome.

carbohydrate
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.

peptide
type: Class
subclass of: carboxamide
subclass of: organic amino compound
subclass of: Restriction
  on property: has part
  some values from: amino-acid residue
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide zwitterion
definition: Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
charge: 0
formula: (C2H2NOR)nC2H3NOR

glycan
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.

bilirubin IXalpha
type: Class
subclass of: dicarboxylic acid
subclass of: biladienes
subclass of: Restriction
  on property: has part
  some values from: 24G7 epitope
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: bilirubin(2-)
definition: A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
charge: 0
formula: C33H36N4O6
inchi: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
inchikey: BPYKTIZUTYGOLE-IFADSCNNSA-N
mass: 584.673
monoisotopicmass: 584.26348

glycoprotein
type: Class
subclass of: conjugated protein
subclass of: carbohydrate derivative
definition: A compound in which a carbohydrate component is covalently bound to a protein component.

morphine
type: Class
subclass of: morphinane alkaloid
subclass of: organic heteropentacyclic compound
subclass of: tertiary amino compound
subclass of: Restriction
  on property: has role
  some values from: geroprotector
subclass of: Restriction
  on property: has role
  some values from: opioid analgesic
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: anaesthetic
subclass of: Restriction
  on property: has role
  some values from: mu-opioid receptor agonist
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: environmental contaminant
subclass of: Restriction
  on property: has role
  some values from: drug allergen
subclass of: Restriction
  on property: has parent hydride
  some values from: morphinan
subclass of: Restriction
  on property: is conjugate base of
  some values from: morphine(1+)
definition: A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy).
charge: 0
formula: C17H19NO3
inchi: InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
inchikey: BQJCRHHNABKAKU-KBQPJGBKSA-N
mass: 285.33770
monoisotopicmass: 285.13649

geroprotector
type: Class
subclass of: protective agent
definition: Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

(S)-nicotine
type: Class
subclass of: 3-(1-methylpyrrolidin-2-yl)pyridine
subclass of: Restriction
  on property: has role
  some values from: phytogenic insecticide
subclass of: Restriction
  on property: has role
  some values from: anxiolytic drug
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: nicotinic acetylcholine receptor agonist
subclass of: Restriction
  on property: has role
  some values from: peripheral nervous system drug
subclass of: Restriction
  on property: has role
  some values from: immunomodulator
subclass of: Restriction
  on property: has role
  some values from: teratogenic agent
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: mitogen
subclass of: Restriction
  on property: has role
  some values from: biomarker
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: (S)-nicotinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-nicotine
definition: A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.
charge: 0
formula: C10H14N2
inchi: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
inchikey: SNICXCGAKADSCV-JTQLQIEISA-N
mass: 162.236
monoisotopicmass: 162.11570
smiles: [H][C@]1(CCCN1C)C1=CC=CN=C1

methanol
type: Class
subclass of: independent continuant
subclass of: volatile organic compound
subclass of: primary alcohol
subclass of: alkyl alcohol
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: Mycoplasma genitalium metabolite
subclass of: Restriction
  on property: has role
  some values from: fuel
subclass of: Restriction
  on property: has role
  some values from: amphiprotic solvent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methoxide
definition: The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
charge: 0
formula: CH4O
inchi: InChI=1S/CH4O/c1-2/h2H,1H3
inchikey: OKKJLVBELUTLKV-UHFFFAOYSA-N
mass: 32.04186
monoisotopicmass: 32.02621
smiles: CO

donor
type: Class
subclass of: chemical role
definition: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.

lipid
type: Class
subclass of: organic molecular entity
definition: 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.

glycosaminoglycan
type: Class
subclass of: aminoglycan
definition: Any polysaccharide containing a substantial proportion of aminomonosaccharide residues.

polysaccharide
type: Class
subclass of: carbohydrate
subclass of: glycan
subclass of: biomacromolecule
definition: A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.

nicotine
type: Class
subclass of: independent continuant
subclass of: racemate
subclass of: Restriction
  on property: has part
  some values from: (S)-nicotine
subclass of: Restriction
  on property: has part
  some values from: (R)-nicotine
subclass of: Restriction
  on property: has role
  some values from: anxiolytic drug
subclass of: Restriction
  on property: has role
  some values from: nicotinic acetylcholine receptor agonist
subclass of: Restriction
  on property: has role
  some values from: peripheral nervous system drug
subclass of: Restriction
  on property: has role
  some values from: immunomodulator
subclass of: Restriction
  on property: has role
  some values from: teratogenic agent
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: mitogen
subclass of: Restriction
  on property: has role
  some values from: biomarker
definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.

acyl group
type: Class
subclass of: organic group
definition: An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.

alkali metal atom
type: Class
subclass of: main group element atom
subclass of: metal atom
subclass of: s-block element atom

alkaloid
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: metabolite
definition: Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.

aminoglycan
type: Class
subclass of: organonitrogen compound
subclass of: polysaccharide derivative

anion
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the electron.

antioxidant
type: Class
subclass of: chemical role
definition: A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.

base
type: Class
subclass of: chemical role
definition: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).

benzenes
type: Class
subclass of: benzenoid aromatic compound
definition: Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.

benzoic acids
type: Class
subclass of: benzenes
subclass of: aromatic carboxylic acid
definition: Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group.

bile salt
type: Class
subclass of: cholanoid
subclass of: organic sodium salt
definition: A sodium salt of the conjugate of any bile acid with either glycine or taurine.

phytogenic insecticide
type: Class
subclass of: insecticide
definition: An insecticide compound naturally occurring in plants.

carbamoyl group
type: Class
subclass of: univalent carboacyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carbamic acid
definition: The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
charge: 0
formula: CH2NO
mass: 44.03272
monoisotopicmass: 44.01364
smiles: *C(N)=O

carbonyl group
type: Class
subclass of: organodiyl group
charge: 0
formula: CO
mass: 28.01010
monoisotopicmass: 27.99491
smiles: O=C(*)*

cofactor
type: Class
subclass of: biochemical role
definition: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).

molecular entity
type: Class
subclass of: chemical entity
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.

drug
type: Class
subclass of: pharmaceutical
definition: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.

monoatomic cation
type: Class
subclass of: monoatomic ion
subclass of: cation

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

ethanols
type: Class
subclass of: primary alcohol
definition: Any primary alcohol based on an ethanol skeleton.

chemical entity
type: Class
definition: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.

biological role
type: Class
subclass of: role
definition: A role played by the molecular entity or part thereof within a biological context.

group
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: atom
definition: A defined linked collection of atoms or a single atom within a molecular entity.

organic heterocyclic compound
type: Class
subclass of: heteroorganic entity
subclass of: organic cyclic compound
subclass of: heterocyclic compound
definition: A cyclic compound having as ring members atoms of carbon and at least of one other element.

hydroxides
type: Class
subclass of: oxygen molecular entity
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydroxy group
definition: Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).

imide
type: Class
subclass of: secondary amide

oxoacid
type: Class
subclass of: independent continuant
subclass of: hydroxides
subclass of: Restriction
  on property: has role
  some values from: Bronsted acid
definition: A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

inorganic anion
type: Class
subclass of: anion
subclass of: inorganic ion

inorganic molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity that contains no carbon.

inorganic oxide
type: Class
subclass of: inorganic molecular entity
subclass of: oxide

insecticide
type: Class
subclass of: pesticide
definition: Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.

salt
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: cation
definition: A salt is an assembly of cations and anions.

monoatomic ion
type: Class
subclass of: ion
subclass of: monoatomic entity
subclass of: atom
disjoint with: atom

organic salt
type: Class
subclass of: salt

ion
type: Class
subclass of: molecular entity
definition: A molecular entity having a net electric charge.

isoquinoline alkaloid
type: Class
subclass of: alkaloid
definition: Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine.

linear tetrapyrrole
type: Class
subclass of: tetrapyrrole

metabolite
type: Class
subclass of: biochemical role
definition: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

metal cation
type: Class
subclass of: monoatomic cation
subclass of: inorganic cation

methyl ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: methanol
definition: Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol.
charge: 0
formula: C2H3O2R
mass: 59.044
monoisotopicmass: 59.01330
smiles: COC([*])=O

molecule
type: Class
subclass of: polyatomic entity
definition: Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.

monoatomic monocation
type: Class
subclass of: monoatomic cation
charge: +1
mass: 0.00000
smiles: [*+]

morphinane alkaloid
type: Class
subclass of: isoquinoline alkaloid
definition: An isoquinoline alkaloid based on a morphinan skeleton and its substituted derivatives.

nitrogen atom
type: Class
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: N
mass: 14.007
monoisotopicmass: 14.00307

nonmetal atom
type: Class
subclass of: atom

organic heteromonocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteromonocyclic compound

organic anion
type: Class
subclass of: anion
subclass of: organic ion
definition: Any organic ion with a net negative charge.

organic cation
type: Class
subclass of: organic ion
subclass of: cation
definition: Any organic ion with a net positive charge.

organic ion
type: Class
subclass of: ion
subclass of: organic molecular entity

organic sulfate
type: Class
subclass of: sulfates
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organosulfate oxoanion
definition: Compounds of the general formula SO3HOR where R is an organyl group

aliphatic alcohol
type: Class
subclass of: alcohol
definition: An alcohol derived from an aliphatic compound.
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: O*

oxide
type: Class
subclass of: oxygen molecular entity
subclass of: heteroatomic molecular entity
definition: An oxide is a chemical compound of oxygen with other chemical elements.

oxygen atom
type: Class
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: O
inchi: InChI=1S/O
inchikey: QVGXLLKOCUKJST-UHFFFAOYSA-N
mass: 15.99940
monoisotopicmass: 15.99491
smiles: [O]

oxygen molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: oxygen atom

pesticide
type: Class
subclass of: application
definition: Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.

pyridine alkaloid
type: Class
subclass of: alkaloid
subclass of: pyridines

pyridines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: organonitrogen heterocyclic compound
definition: Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives.

pyrrolidine alkaloid
type: Class
subclass of: alkaloid
subclass of: pyrrolidines

sodium atom
type: Class
subclass of: alkali metal atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
charge: 0
formula: Na
inchi: InChI=1S/Na
inchikey: KEAYESYHFKHZAL-UHFFFAOYSA-N
mass: 22.98977
monoisotopicmass: 22.98977
smiles: [Na]

sodium molecular entity
type: Class
subclass of: alkali metal molecular entity
subclass of: Restriction
  on property: has part
  some values from: sodium atom

sodium salt
type: Class
subclass of: sodium molecular entity
subclass of: alkali metal salt
subclass of: Restriction
  on property: has part
  some values from: sodium(1+)
definition: Any alkali metal salt having sodium(1+) as the cation.

sulfuric ester
type: Class
subclass of: ester
subclass of: sulfuric acid derivative
definition: An ester of an alcohol and sulfuric acid.
charge: 0
formula: O4SR2
mass: 96.06300
monoisotopicmass: 95.95173
smiles: [*]OS(=O)(=O)O[*]

sulfates
type: Class
subclass of: sulfuric acid derivative
definition: Salts and esters of sulfuric acid

sulfur atom
type: Class
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: S
inchi: InChI=1S/S
inchikey: NINIDFKCEFEMDL-UHFFFAOYSA-N
mass: 32.06600
monoisotopicmass: 31.97207
smiles: [S]

sulfur molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: sulfur atom

sulfuric acid
type: Class
subclass of: sulfur oxoacid
subclass of: Restriction
  on property: has role
  some values from: catalyst
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogensulfate
definition: A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.
charge: 0
formula: H2O4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-N
mass: 98.07948
monoisotopicmass: 97.96738
smiles: [H]OS(=O)(=O)O[H]

tetrapyrrole
type: Class
subclass of: heteroarene
subclass of: polypyrrole
definition: A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.

organic heterobicyclic compound
type: Class
subclass of: heterobicyclic compound
subclass of: organic heteropolycyclic compound

univalent carboacyl group
type: Class
subclass of: carboacyl group
definition: A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.

zwitterion
type: Class
subclass of: dipolar compound
definition: A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).

carbon atom
type: Class
subclass of: nonmetal atom
subclass of: carbon group element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: C
inchi: InChI=1S/C
inchikey: OKTJSMMVPCPJKN-UHFFFAOYSA-N
mass: 12.01070
monoisotopicmass: 12.00000
smiles: [C]

cocaine
type: Class
subclass of: methyl ester
subclass of: benzoate ester
subclass of: tropane alkaloid
subclass of: tertiary amino compound
subclass of: Restriction
  on property: has role
  some values from: central nervous system stimulant
subclass of: Restriction
  on property: has role
  some values from: sympathomimetic agent
subclass of: Restriction
  on property: has role
  some values from: adrenergic uptake inhibitor
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: local anaesthetic
subclass of: Restriction
  on property: has role
  some values from: sodium channel blocker
subclass of: Restriction
  on property: has role
  some values from: vasoconstrictor agent
subclass of: Restriction
  on property: has role
  some values from: serotonin uptake inhibitor
subclass of: Restriction
  on property: has role
  some values from: dopamine uptake inhibitor
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: environmental contaminant
subclass of: Restriction
  on property: is conjugate base of
  some values from: cocaine(1+)
definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
charge: 0
formula: C17H21NO4
inchi: InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1
inchikey: ZPUCINDJVBIVPJ-LJISPDSOSA-N
mass: 303.35290
monoisotopicmass: 303.14706

carbamic acid
type: Class
subclass of: organonitrogen compound
subclass of: carbon oxoacid
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbamate
definition: A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
charge: 0
formula: CH3NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-N
mass: 61.04006
monoisotopicmass: 61.01638
smiles: NC(O)=O

ammonium
type: Class
subclass of: independent continuant
subclass of: nitrogen hydride
subclass of: onium cation
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: ammonia
definition: An onium cation obtained by protonation of ammonia.
charge: +1
formula: H4N
inchi: InChI=1S/H3N/h1H3/p+1
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-O
mass: 18.03850
monoisotopicmass: 18.03383
smiles: [H][N+]([H])([H])[H]

dicarboxylic acid dianion
type: Class
subclass of: dicarboxylic acid anion
subclass of: carboxylic acid dianion
definition: A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.
charge: -2
formula: C2O4R
mass: 88.019
monoisotopicmass: 87.97966
smiles: [O-]C(=O)[*]C([O-])=O

carboxylic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carboxylic acid
definition: The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
charge: -1
formula: CO2R
mass: 44.00950
monoisotopicmass: 43.98983
smiles: [O-]C([*])=O

sodium(1+)
type: Class
subclass of: monoatomic monocation
subclass of: alkali metal cation
subclass of: elemental sodium
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: A monoatomic monocation obtained from sodium.
charge: +1
formula: Na
inchi: InChI=1S/Na/q+1
inchikey: FKNQFGJONOIPTF-UHFFFAOYSA-N
mass: 22.98977
monoisotopicmass: 22.98922
smiles: [Na+]

azanide
type: Class
subclass of: nitrogen hydride
subclass of: monovalent inorganic anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydridonitrate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: ammonia
charge: -1
formula: H2N
inchi: InChI=1S/H2N/h1H2/q-1
inchikey: HYGWNUKOUCZBND-UHFFFAOYSA-N
mass: 16.02262
monoisotopicmass: 16.01927
smiles: [H][N-][H]

hydridonitrate(2-)
type: Class
subclass of: nitrogen hydride
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: azanide
definition: A divalent inorganic anion resulting from the removal of two protons from ammonia.
charge: -2
formula: HN
inchi: InChI=1S/HN/h1H/q-2
inchikey: DZQYTNGKSBCIOE-UHFFFAOYSA-N
mass: 15.01468
monoisotopicmass: 15.01200
smiles: [N--][H]

oxonium
type: Class
subclass of: oxygen hydride
subclass of: onium cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: water
charge: +1
formula: H3O
inchi: InChI=1S/H2O/h1H2/p+1
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-O
mass: 19.02322
monoisotopicmass: 19.01784
smiles: [H][O+]([H])[H]

alcohol
type: Class
subclass of: organic hydroxy compound
definition: A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: O[*]

saccharin
type: Class
subclass of: independent continuant
subclass of: 1,2-benzisothiazole
subclass of: N-sulfonylcarboxamide
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: sweetening agent
subclass of: Restriction
  on property: has role
  some values from: environmental contaminant
definition: A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
charge: 0
formula: C7H5NO3S
inchi: InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
inchikey: CVHZOJJKTDOEJC-UHFFFAOYSA-N
mass: 183.18500
monoisotopicmass: 182.99901
smiles: O=C1NS(=O)(=O)c2ccccc12

amide
type: Class
subclass of: nitrogen molecular entity
definition: An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.

application
type: Class
subclass of: role
definition: Intended use of the molecular entity or part thereof by humans.

fundamental particle
type: Class
subclass of: subatomic particle
definition: A particle not known to have substructure.

monoatomic entity
type: Class
subclass of: elemental molecular entity
definition: A monoatomic entity is a molecular entity consisting of a single atom.

oxoacid derivative
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has functional parent
  some values from: oxoacid

inorganic hydride
type: Class
subclass of: inorganic molecular entity
subclass of: hydrides

organic fundamental parent
type: Class
subclass of: organic hydride
subclass of: organic molecular entity
definition: An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.

inorganic group
type: Class
subclass of: group
definition: Any substituent group which does not contain carbon.

organic group
type: Class
subclass of: group
subclass of: Restriction
  on property: is substituent group from
  some values from: organic molecular entity
definition: Any substituent group or skeleton containing carbon.

organyl group
type: Class
subclass of: organic univalent group
definition: Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.

atom
type: Class
subclass of: chemical entity
subclass of: atom
subclass of: Restriction
  on property: has part
  some values from: electron
definition: A chemical entity constituting the smallest component of an element having the chemical properties of the element.
label: uncharged atom

atomic nucleus
type: Class
subclass of: nuclear particle
subclass of: Restriction
  on property: has part
  some values from: nucleon
definition: A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
comment: Some people may be uncomfortable calling every proton an atomic nucleus
comment: This is equivalent to CHEBI:33252

nucleon
type: Class
subclass of: baryon
subclass of: nuclear particle
definition: Heavy nuclear particle: proton or neutron.

primary amide
type: Class
subclass of: amide
definition: A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.

secondary amide
type: Class
subclass of: amide
definition: A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group.

elemental molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity all atoms of which have the same atomic number.

organosulfur compound
type: Class
subclass of: sulfur molecular entity
subclass of: organochalcogen compound
definition: An organosulfur compound is a compound containing at least one carbon-sulfur bond.

polyatomic anion
type: Class
subclass of: anion
subclass of: polyatomic ion
definition: An anion consisting of more than one atom.

antimicrobial agent
type: Class
subclass of: biological role
definition: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.

nutrient
type: Class
subclass of: food component
definition: A nutrient is a food component that an organism uses to survive and grow.

heteroorganic entity
type: Class
subclass of: organic molecular entity
definition: A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.

food
type: Class
subclass of: physiological role
subclass of: Restriction
  on property: has part
  some values from: food component
definition: A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.

fuel
type: Class
subclass of: application
definition: An energy-rich substance that can be transformed with release of usable energy.

alkali metal molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: alkali metal atom
definition: A molecular entity containing one or more atoms of an alkali metal.

pnictogen
type: Class
subclass of: p-block element atom
definition: Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.

pnictogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: pnictogen
definition: A p-block molecular entity containing any pnictogen.

chalcogen
type: Class
subclass of: p-block element atom
definition: Any p-block element belonging to the group 16 family of the periodic table.

chalcogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: chalcogen
definition: Any p-block molecular entity containing a chalcogen.

carbon group element atom
type: Class
subclass of: p-block element atom

carboxylic ester
type: Class
subclass of: ester
subclass of: carbonyl compound
definition: An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.
charge: 0
formula: CO2R2
mass: 44.010
monoisotopicmass: 43.98983
smiles: [*]C(=O)O[*]

main group element atom
type: Class
subclass of: atom
definition: An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.

sulfur oxoacid
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoacid

sulfur oxoacid derivative
type: Class
subclass of: sulfur molecular entity
subclass of: oxoacid derivative

sulfur oxoanion
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoanion

chalcogen oxoacid
type: Class
subclass of: oxoacid
subclass of: Restriction
  on property: has role
  some values from: inorganic acid

chalcogen oxoanion
type: Class
subclass of: oxoanion

alkali metal cation
type: Class
subclass of: metal cation

metal atom
type: Class
subclass of: atom
definition: An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.

alpha-amino-acid anion
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: alpha-amino acid
definition: An amino-acid anion obtained by deprotonation of any alpha-amino acid.

s-block element atom
type: Class
subclass of: atom

p-block element atom
type: Class
subclass of: main group element atom
definition: Any main group element atom belonging to the p-block of the periodic table.

carboxylic acid
type: Class
subclass of: carbon oxoacid
subclass of: carbonyl compound
subclass of: organic acid
subclass of: Restriction
  on property: has part
  some values from: carboxy group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carboxylic acid anion
definition: A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
charge: 0
formula: CHO2R
mass: 45.01740
monoisotopicmass: 44.99765
smiles: OC([*])=O

main group molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: main group element atom
definition: A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.

carbon group molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon group element atom

cyclic compound
type: Class
subclass of: molecule
definition: Any molecule that consists of a series of atoms joined together to form a ring.

homocyclic compound
type: Class
subclass of: cyclic compound
definition: A cyclic compound having as ring members atoms of the same element only.

carbocyclic compound
type: Class
subclass of: homocyclic compound
subclass of: organic cyclic compound
definition: A homocyclic compound in which all of the ring members are carbon atoms.

hydrogen molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydrogen atom

polycyclic compound
type: Class
subclass of: cyclic compound

bicyclic compound
type: Class
subclass of: cyclic compound
definition: A molecule that features two fused rings.

aromatic compound
type: Class
subclass of: cyclic compound
definition: A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.

organic aromatic compound
type: Class
subclass of: aromatic compound
subclass of: organic cyclic compound

monocyclic compound
type: Class
subclass of: cyclic compound

heteromonocyclic compound
type: Class
subclass of: monocyclic compound
subclass of: heterocyclic compound

heteropolycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: heterocyclic compound
definition: A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.

heterobicyclic compound
type: Class
subclass of: bicyclic compound
subclass of: heterocyclic compound
definition: A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.

s-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: s-block element atom
definition: An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.

p-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: p-block element atom
definition: A main group molecular entity that contains one or more atoms of a p-block element.

hydrides
type: Class
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
definition: Hydrides are chemical compounds of hydrogen with other chemical elements.

oxygen hydride
type: Class
subclass of: chalcogen hydride

biomacromolecule
type: Class
subclass of: macromolecule
subclass of: organic molecular entity
definition: A macromolecule formed by a living organism.

information biomacromolecule
type: Class
subclass of: biomacromolecule

proteinogenic amino-acid residue
type: Class
subclass of: alpha-amino-acid residue

polyatomic cation
type: Class
subclass of: polyatomic ion
subclass of: cation
definition: A cation consisting of more than one atom.

alpha-amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alpha-amino-acid anion
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino acid zwitterion
definition: An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
charge: 0
formula: C2H4NO2R
mass: 74.05870
monoisotopicmass: 74.02420
smiles: NC([*])C(O)=O

amino-acid residue
type: Class
subclass of: organic group
subclass of: Restriction
  on property: is substituent group from
  some values from: amino acid
definition: When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.

amino acid
type: Class
subclass of: carboxylic acid
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amino-acid anion
definition: A carboxylic acid containing one or more amino groups.

alpha-amino-acid residue
type: Class
subclass of: amino-acid residue
subclass of: Restriction
  on property: is substituent group from
  some values from: alpha-amino acid

carbohydrate acid
type: Class
subclass of: carbohydrate
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid anion

carbohydrate acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid

organic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: organic molecular entity
definition: An organic compound having at least one hydroxy group attached to a carbon atom.

organic cyclic compound
type: Class
subclass of: cyclic compound
subclass of: organic molecule
definition: Any organic molecule that consists of atoms connected in the form of a ring.

heteroarene
type: Class
subclass of: organic heterocyclic compound
subclass of: organic aromatic compound
definition: A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).

benzenoid aromatic compound
type: Class
subclass of: carbocyclic compound
subclass of: organic aromatic compound

conjugated protein
type: Class
subclass of: protein
definition: Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion.

macromolecule
type: Class
subclass of: polyatomic entity
definition: A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

aromatic carboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: organic aromatic compound
subclass of: Restriction
  on property: is conjugate acid of
  some values from: aromatic carboxylate
definition: Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.

reagent
type: Class
subclass of: application
definition: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.

macronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.

nitrogen hydride
type: Class
subclass of: pnictogen hydride
subclass of: nitrogen molecular entity

azane
type: Class
subclass of: nitrogen hydride
definition: Saturated acyclic nitrogen hydrides having the general formula NnHn+2.

inhibitor
type: Class
subclass of: biological role
definition: A substance that diminishes the rate of a chemical reaction.

catalyst
type: Class
subclass of: chemical role
definition: A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.

amino acid zwitterion
type: Class
subclass of: zwitterion
definition: The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.

ammonium ion derivative
type: Class
subclass of: polyatomic cation
subclass of: nitrogen molecular entity
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc).

central nervous system stimulant
type: Class
subclass of: central nervous system drug
definition: Any drug that enhances the activity of the central nervous system.

steroid
type: Class
subclass of: lipid
subclass of: organic polycyclic compound
definition: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.
charge: 0
formula: C19H31R
mass: 259.450
monoisotopicmass: 259.24258
smiles: C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C

organonitrogen compound
type: Class
subclass of: heteroorganic entity
subclass of: nitrogen molecular entity
definition: Any heteroorganic entity containing at least one carbon-nitrogen bond.

oxoanion
type: Class
subclass of: oxide
subclass of: polyatomic anion
definition: An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.

antiinfective agent
type: Class
subclass of: drug
definition: A substance used in the prophylaxis or therapy of infectious diseases.

central nervous system drug
type: Class
subclass of: drug
definition: A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.

psychotropic drug
type: Class
subclass of: central nervous system drug
definition: A loosely defined grouping of drugs that have effects on psychological function.

tranquilizing drug
type: Class
subclass of: psychotropic drug
subclass of: central nervous system depressant
definition: A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour.

anxiolytic drug
type: Class
subclass of: tranquilizing drug
definition: Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.

alkali metal salt
type: Class
subclass of: salt
subclass of: alkali metal molecular entity

analgesic
type: Class
subclass of: drug
subclass of: pharmacological role
definition: An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.

opioid analgesic
type: Class
subclass of: analgesic
definition: A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.

central nervous system depressant
type: Class
subclass of: central nervous system drug
definition: A loosely defined group of drugs that tend to reduce the activity of the central nervous system.

alkaloid fundamental parent
type: Class
subclass of: natural product fundamental parent

natural product fundamental parent
type: Class
subclass of: organic fundamental parent

steroid fundamental parent
type: Class
subclass of: steroid
subclass of: natural product fundamental parent

cholane
type: Class
subclass of: steroid fundamental parent
charge: 0
formula: C24H42
inchi: InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1
inchikey: QSHQKIURKJITMZ-BRPMRXRMSA-N
mass: 330.59028
monoisotopicmass: 330.32865

sympathomimetic agent
type: Class
subclass of: adrenergic agent
definition: A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

cardiovascular drug
type: Class
subclass of: drug
definition: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.

carbon oxoacid
type: Class
subclass of: oxoacid
subclass of: organooxygen compound

flavouring agent
type: Class
subclass of: food additive
definition: A food additive that is used to added improve the taste or odour of a food.

vasodilator agent
type: Class
subclass of: cardiovascular drug
definition: A drug used to cause dilation of the blood vessels.

adrenergic uptake inhibitor
type: Class
subclass of: adrenergic agent
definition: Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

morphinan
type: Class
subclass of: morphinane alkaloid
subclass of: isoquinoline alkaloid fundamental parent
charge: 0
formula: C16H21N
inchi: InChI=1S/C16H21N/c1-2-6-13-12(5-1)11-15-14-7-3-4-8-16(13,14)9-10-17-15/h1-2,5-6,14-15,17H,3-4,7-11H2/t14-,15+,16-/m0/s1
inchikey: INAXVFBXDYWQFN-XHSDSOJGSA-N
mass: 227.34468
monoisotopicmass: 227.16740

dicarboxylic acid
type: Class
subclass of: dicarboxylic acids and O-substituted derivatives
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dicarboxylic acid anion
definition: Any carboxylic acid containing two carboxy groups.

dicarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: dicarboxylic acid

ester
type: Class
subclass of: organooxygen compound
definition: A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter.

xenobiotic
type: Class
subclass of: biological role
definition: A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.

sulfated glycosaminoglycan
type: Class
subclass of: glycosaminoglycan
subclass of: carbohydrate sulfate

carbohydrate sulfate
type: Class
subclass of: organic sulfate
subclass of: sulfuric ester
subclass of: carbohydrate derivative

pnictogen hydride
type: Class
subclass of: inorganic hydride
subclass of: pnictogen molecular entity

neurotransmitter agent
type: Class
subclass of: drug
subclass of: pharmacological role
definition: A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.

benzoate ester
type: Class
subclass of: carboxylic ester
subclass of: aromatic ester
subclass of: Restriction
  on property: has functional parent
  some values from: benzoic acids
definition: Esters of benzoic acid or substituted benzoic acids.

cholanoid
type: Class
subclass of: steroid
subclass of: Restriction
  on property: has parent hydride
  some values from: cholane

protein
type: Class
subclass of: information biomacromolecule
subclass of: Restriction
  on property: has part
  some values from: protein polypeptide chain
definition: A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome.

bile acid salt
type: Class
subclass of: organic salt
subclass of: cholanoid
definition: A salt of a bile acid.

local anaesthetic
type: Class
subclass of: anaesthetic
definition: Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.

lepton
type: Class
subclass of: fundamental particle
subclass of: fermion
definition: Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).

baryon
type: Class
subclass of: fermion
subclass of: hadron
definition: Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).

fermion
type: Class
subclass of: subatomic particle
definition: Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.

subatomic particle
type: Class
subclass of: material entity
definition: A particle smaller than an atom.

composite particle
type: Class
subclass of: subatomic particle
definition: A subatomic particle known to have substructure (i.e. consisting of smaller particles).

hadron
type: Class
subclass of: composite particle
definition: Hadron is a subatomic particle which experiences the strong force.

nuclear particle
type: Class
subclass of: subatomic particle
definition: A nucleus or any of its constituents in any of their energy states.

polyatomic entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: group
definition: Any molecular entity consisting of more than one atom.

polyatomic ion
type: Class
subclass of: ion
subclass of: polyatomic entity
definition: An ion consisting of more than one atom.

carbonyl compound
type: Class
subclass of: organic oxo compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
definition: Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.

organic oxo compound
type: Class
subclass of: organic molecule
subclass of: Restriction
  on property: has part
  some values from: oxo group
definition: Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.

biladienes
type: Class
subclass of: linear tetrapyrrole
definition: Compounds based on a biladiene skeleton.

chalcogen hydride
type: Class
subclass of: inorganic hydride
subclass of: chalcogen molecular entity

inorganic ion
type: Class
subclass of: inorganic molecular entity
subclass of: ion

inorganic cation
type: Class
subclass of: inorganic ion
subclass of: cation

cation
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the proton.

organochalcogen compound
type: Class
subclass of: heteroorganic entity
subclass of: chalcogen molecular entity
definition: An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.

organooxygen compound
type: Class
subclass of: oxygen molecular entity
subclass of: organochalcogen compound
definition: An organochalcogen compound containing at least one carbon-oxygen bond.

amino-acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: organonitrogen compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: amino acid

organic hydride
type: Class
subclass of: hydrides

mononuclear parent hydride
type: Class
subclass of: hydrides

elemental sodium
type: Class
subclass of: sodium molecular entity

tropane alkaloid
type: Class
subclass of: alkaloid
subclass of: azabicycloalkane

mucopolysaccharide
type: Class
subclass of: glycosaminoglycan
definition: Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid.

acid
type: Class
subclass of: chemical role
definition: An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).

heteroatomic molecular entity
type: Class
subclass of: polyatomic entity
definition: A molecular entity consisting of two or more chemical elements.

carboxamide
type: Class
subclass of: primary amide
subclass of: organonitrogen compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbamoyl group
definition: An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.
charge: 0
formula: CNOR3
mass: 42.01680
monoisotopicmass: 41.99799
smiles: [*]C(=O)N([*])[*]

mixed diacylamine
type: Class
subclass of: imide
definition: Any imide in which the acyl substituents are any two from carboacyl, sulfonyl and phosphoryl

sulfuric acid derivative
type: Class
subclass of: sulfur oxoacid derivative
subclass of: Restriction
  on property: has functional parent
  some values from: sulfuric acid

carboacyl group
type: Class
subclass of: acyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carboxylic acid
definition: A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.

benzothiazoles
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound
subclass of: organosulfur heterocyclic compound

adrenergic agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.

polypyrrole
type: Class
subclass of: organonitrogen heterocyclic compound
definition: A compound composed of two or more pyrrole units.

organonitrogen heterocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: organonitrogen compound
definition: Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.

organosulfur heterocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: organosulfur compound

organic heteropentacyclic compound
type: Class
subclass of: organic heteropolycyclic compound

organic heteropolycyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteropolycyclic compound

pyrrolidines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: organonitrogen heterocyclic compound
definition: Any of a class of heterocyclic amines having a saturated five-membered ring.

azabicycloalkane
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound

cholinergic drug
type: Class
subclass of: neurotransmitter agent
definition: Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.

cholinergic agonist
type: Class
subclass of: cholinergic drug
definition: Any drug that binds to and activates cholinergic receptors.

isoquinoline alkaloid fundamental parent
type: Class
subclass of: alkaloid fundamental parent

membrane transport modulator
type: Class
subclass of: biophysical role
definition: Any agent that affects the transport of molecular entities across a biological membrane.

sodium channel blocker
type: Class
subclass of: sodium channel modulator
definition: An agent that inhibits sodium influx through cell membranes.

organic sodium salt
type: Class
subclass of: organic salt
subclass of: sodium salt

carboxylic acid dianion
type: Class
subclass of: carboxylic acid anion
definition: Any dianion containing at least one carboxy group.

anaesthetic
type: Class
subclass of: drug
definition: Substance which produces loss of feeling or sensation.

sodium channel modulator
type: Class
subclass of: membrane transport modulator

Bronsted acid
type: Class
subclass of: donor
subclass of: acid
definition: A molecular entity capable of donating a hydron to an acceptor (Bronsted base).

Bronsted base
type: Class
subclass of: acceptor
subclass of: base
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).

Lewis base
type: Class
subclass of: donor
subclass of: base
definition: A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.

(R)-nicotine
type: Class
subclass of: 3-(1-methylpyrrolidin-2-yl)pyridine
subclass of: Restriction
  on property: is conjugate base of
  some values from: (R)-nicotinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-nicotine
definition: A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has R-configuration.
charge: 0
formula: C10H14N2
inchi: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m1/s1
inchikey: SNICXCGAKADSCV-SNVBAGLBSA-N
mass: 162.23160
monoisotopicmass: 162.11570
smiles: CN1CCC[C@@H]1c1cccnc1

hydroxy group
type: Class
subclass of: inorganic group
charge: 0
formula: HO
mass: 17.00734
monoisotopicmass: 17.00274
smiles: *O[H]

hydrogensulfate
type: Class
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: sulfuric acid
charge: -1
formula: HO4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-M
mass: 97.07154
monoisotopicmass: 96.96010
smiles: [H]OS([O-])(=O)=O

oxo group
type: Class
subclass of: inorganic group
charge: 0
formula: O
mass: 15.99940
monoisotopicmass: 15.99491
smiles: O=*

N-alkylpyrrolidine
type: Class
subclass of: pyrrolidines
subclass of: tertiary amino compound

solvent
type: Class
subclass of: application
subclass of: chemical role
definition: A liquid that can dissolve other substances (solutes) without any change in their chemical composition.

carboxy group
type: Class
subclass of: organyl group
charge: 0
formula: CHO2
mass: 45.01744
monoisotopicmass: 44.99765
smiles: *C(=O)O

indicator
type: Class
subclass of: application
definition: Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.

nicotinic acetylcholine receptor agonist
type: Class
subclass of: cholinergic agonist
definition: An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.

sulfur oxide
type: Class
subclass of: inorganic oxide
subclass of: sulfur molecular entity

antiseptic drug
type: Class
subclass of: antiinfective agent
definition: A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).

disinfectant
type: Class
subclass of: antimicrobial agent
definition: An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.

serotonergic drug
type: Class
subclass of: neurotransmitter agent

polar solvent
type: Class
subclass of: solvent
definition: A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.

protic solvent
type: Class
subclass of: Bronsted acid
subclass of: polar solvent
definition: A polar solvent that is capable of acting as a hydron (proton) donor.

protophilic solvent
type: Class
subclass of: Bronsted base
subclass of: polar solvent
definition: Solvent that is capable of acting as a hydron (proton) acceptor.

amphiprotic solvent
type: Class
subclass of: protic solvent
subclass of: protophilic solvent
definition: Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.

dopaminergic agent
type: Class
subclass of: neurotransmitter agent
definition: A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.

agonist
type: Class
subclass of: pharmacological role
definition: Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.

antagonist
type: Class
subclass of: pharmacological role
definition: Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.

peripheral nervous system drug
type: Class
subclass of: drug
definition: A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.

hydrogen atom
type: Class
subclass of: inorganic molecular entity
subclass of: nonmetal atom
subclass of: s-block element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: H
inchi: InChI=1S/H
inchikey: YZCKVEUIGOORGS-UHFFFAOYSA-N
mass: 1.00794
monoisotopicmass: 1.00783
smiles: [H]

organic amino compound
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: Bronsted base
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonia
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.

protective agent
type: Class
subclass of: drug
definition: Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.

onium compound
type: Class
subclass of: heteroatomic molecular entity

onium cation
type: Class
subclass of: onium compound
definition: Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.

sweetening agent
type: Class
subclass of: flavouring agent
definition: Substance that sweeten food, beverages, medications, etc.

vasoconstrictor agent
type: Class
subclass of: cardiovascular drug
definition: Drug used to cause constriction of the blood vessels.

alkyl alcohol
type: Class
subclass of: aliphatic alcohol
definition: An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position.

immunomodulator
type: Class
subclass of: drug
subclass of: biological role
definition: Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

organic molecular entity
type: Class
subclass of: carbon group molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon atom
definition: Any molecular entity that contains carbon.

allergen
type: Class
subclass of: aetiopathogenetic role
definition: A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.

teratogenic agent
type: Class
subclass of: aetiopathogenetic role
definition: A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.

role
type: Class
subclass of: PATO_0000001
definition: A role is particular behaviour which a material entity may exhibit.

neurotoxin
type: Class
subclass of: aetiopathogenetic role
subclass of: poison
definition: A poison that interferes with the functions of the nervous system.

serotonin uptake inhibitor
type: Class
subclass of: serotonergic drug
definition: A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.

tertiary amino compound
type: Class
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: tertiary ammonium ion
definition: A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups.

dopamine uptake inhibitor
type: Class
subclass of: dopaminergic agent
definition: A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

chemical role
type: Class
subclass of: role
definition: A role played by the molecular entity or part thereof within a chemical context.

nitrogen molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: nitrogen atom

dipolar compound
type: Class
subclass of: organic molecule
definition: An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case.

organodiyl group
type: Class
subclass of: organic divalent group
definition: Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).

organic divalent group
type: Class
subclass of: organic group

organic univalent group
type: Class
subclass of: organic group

organic polycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: organic cyclic compound

methoxide
type: Class
subclass of: independent continuant
subclass of: organic anion
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: methanol
definition: An organic anion that is the conjugate base of methanol.
charge: -1
formula: CH3O
inchi: InChI=1S/CH3O/c1-2/h1H3/q-1
inchikey: NBTOZLQBSIZIKS-UHFFFAOYSA-N
mass: 31.03390
monoisotopicmass: 31.01894
smiles: C[O-]

ethoxide
type: Class
subclass of: independent continuant
subclass of: organic anion
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: ethanol
definition: An organic anion that is the conjugate base of ethanol.
charge: -1
formula: C2H5O
inchi: InChI=1S/C2H5O/c1-2-3/h2H2,1H3/q-1
inchikey: HHFAWKCIHAUFRX-UHFFFAOYSA-N
mass: 45.06050
monoisotopicmass: 45.03459
smiles: CC[O-]

biochemical role
type: Class
subclass of: biological role
definition: A biological role played by the molecular entity or part thereof within a biochemical context.

biophysical role
type: Class
subclass of: biological role

aetiopathogenetic role
type: Class
subclass of: biological role
definition: A role played by the molecular entity or part thereof which causes the development of a pathological process.

pharmacological role
type: Class
subclass of: biological role
definition: A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.

physiological role
type: Class
subclass of: biological role

pharmaceutical
type: Class
subclass of: application
definition: Any substance introduced into a living organism with therapeutic or diagnostic purpose.

mitogen
type: Class
subclass of: biological role
definition: A chemical substance that encourages a cell to commence cell division, triggering mitosis.

inorganic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: inorganic molecular entity

epitope
type: Class
subclass of: biological role
definition: The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.

polyanionic macromolecule
type: Class
subclass of: ionic macromolecule
definition: A polymer carrying multiple negative charges.

ionic macromolecule
type: Class
subclass of: macromolecule
definition: A macromolecule containing ionic groups.

mu-opioid receptor agonist
type: Class
subclass of: mu-opioid agent
subclass of: opioid receptor agonist
definition: A compound that exhibits agonist activity at the mu-opioid receptor.

1,2-benzisothiazole
type: Class
subclass of: benzothiazoles
definition: A benzothiazole consisting of a benzene ring fused to an isothiazole.

heterocyclic compound
type: Class
subclass of: cyclic compound
definition: A cyclic compound having as ring members atoms of at least two different elements.

bilirubin(2-)
type: Class
subclass of: independent continuant
subclass of: dicarboxylic acid dianion
subclass of: linear tetrapyrrole anion
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: bilirubin IXalpha
definition: A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.
charge: -2
formula: C33H34N4O6
inchi: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-
inchikey: BPYKTIZUTYGOLE-IFADSCNNSA-L
mass: 582.64630
monoisotopicmass: 582.24893

morphine(1+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: morphine
definition: The conjugate acid of morphine arising from protonation of the tertiary amino group; major species at pH 7.3.
charge: +1
formula: C17H20NO3
inchi: InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/p+1/t10-,11+,13-,16-,17-/m0/s1
inchikey: BQJCRHHNABKAKU-KBQPJGBKSA-O
mass: 286.34560
monoisotopicmass: 286.14377

organosulfate oxoanion
type: Class
subclass of: organic anion
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: has functional parent
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: organic sulfate
definition: An organic anion of general formula RS(=O)2O(-) where R is an organyl group.
charge: -1
formula: O4SR
mass: 96.06300
monoisotopicmass: 95.95173
smiles: [O-]S(=O)(=O)O[*]

biomarker
type: Class
subclass of: indicator
definition: A substance used as an indicator of a biological state.

linear tetrapyrrole anion
type: Class
subclass of: organic anion
definition: An organic anion arising from deprotonation of a acyclic tetrapyrrole compound.

nucleophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis base
definition: A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.

(S)-nicotinium(1+)
type: Class
subclass of: independent continuant
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: (S)-nicotine
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-nicotinium(1+)
definition: The conjugate acid of (S)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3.
charge: +1
formula: C10H15N2
inchi: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m0/s1
inchikey: SNICXCGAKADSCV-JTQLQIEISA-O
mass: 163.23900
monoisotopicmass: 163.12297
smiles: C[NH+]1CCC[C@H]1c1cccnc1

chemical substance
type: Class
subclass of: chemical entity
definition: A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.

mixture
type: Class
subclass of: chemical substance
definition: A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind.

polymer
type: Class
subclass of: mixture
subclass of: Restriction
  on property: has part
  some values from: macromolecule
definition: A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc..

cocaine(1+)
type: Class
subclass of: ammonium ion derivative
subclass of: tropane alkaloid
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cocaine
definition: The conjugate base of cocaine arising from protonation of the tertiary amino group; major species at pH 7.3.
charge: +1
formula: C17H22NO4
inchi: InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/p+1/t12-,13+,14-,15+/m0/s1
inchikey: ZPUCINDJVBIVPJ-LJISPDSOSA-O
mass: 304.36090
monoisotopicmass: 304.15433

ionic polymer
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has part
  some values from: ionic macromolecule
definition: An ionic polymer is a polymer, composed of ionic macromolecules.

monovalent inorganic cation
type: Class
subclass of: inorganic cation
definition: An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.

peptide zwitterion
type: Class
subclass of: zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide
definition: Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged.
charge: 0
formula: C2H4NO2R(C2H2NOR)n

opioid agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter.

mu-opioid agent
type: Class
subclass of: opioid agent
definition: Any agent that acts on a mu-opioid receptor.

opioid receptor agonist
type: Class
subclass of: agonist
subclass of: opioid agent
definition: An agent that selectively binds to and activates an opioid receptor.

NMDA receptor antagonist
type: Class
subclass of: excitatory amino acid antagonist
definition: Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.

excitatory amino acid antagonist
type: Class
subclass of: antagonist
definition: Any substance which inhibits the action of receptors for excitatory amino acids.

racemate
type: Class
subclass of: mixture
definition: A racemate is an equimolar mixture of a pair of enantiomers.

polyanionic polymer
type: Class
subclass of: ionic polymer
subclass of: Restriction
  on property: has part
  some values from: polyanionic macromolecule
definition: A polymer, composed of polyanion macromolecules.

aromatic ester
type: Class
subclass of: organic aromatic compound
subclass of: ester
definition: An ester where the ester linkage is bonded directly to an aromatic system.

carbohydrate derivative
type: Class
subclass of: carbohydrates and carbohydrate derivatives
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate
definition: Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.

carbohydrate acid derivative
type: Class
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid derivative anion
definition: A carbohydrate derivative that is formally obtained from a carbohydrate acid.

carbohydrate acid derivative anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid derivative
definition: A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.

protein kinase C agonist
type: Class
subclass of: protein kinase agonist
definition: An agonist that selectively binds to and activates a protein kinase C receptor

food additive
type: Class
subclass of: application
subclass of: food component
definition: Any substance which is added to food to preserve or enhance its flavour and/or appearance.

protein kinase agonist
type: Class
subclass of: agonist
definition: An agonist that selectively binds to and activates a protein kinase receptor.

one-carbon compound
type: Class
subclass of: organic molecular entity
definition: An organic molecular entity containing a single carbon atom (C1).

organic acid
type: Class
subclass of: organic molecular entity
definition: Any organic molecular entity that is acidic and contains carbon in covalent linkage.

poison
type: Class
subclass of: biological role
definition: Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.

polysaccharide derivative
type: Class
subclass of: glycan
subclass of: biomacromolecule
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: polysaccharide
definition: A carbohydrate derivative that is any derivative of a polysaccharide.

organic molecule
type: Class
subclass of: molecule
subclass of: organic molecular entity
definition: Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.

exopolysaccharide
type: Class
subclass of: biomacromolecule
definition: A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.

eukaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.

animal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.

mammalian metabolite
type: Class
subclass of: animal metabolite
definition: Any animal metabolite produced during a metabolic reaction in mammals.

mouse metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).

Saccharomyces cerevisiae metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).

prokaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.

greenhouse gas
type: Class
subclass of: chemical role
definition: A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.

EC 3.* (hydrolase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).

EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).

EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).

plant metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.

fungal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.

bacterial metabolite
type: Class
subclass of: prokaryotic metabolite
definition: Any prokaryotic metabolite produced during a metabolic reaction in bacteria.

Escherichia coli metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.

human metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).

EC 3.5.1.4 (amidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).

food component
type: Class
subclass of: physiological role
definition: A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.

environmental contaminant
type: Class
subclass of: chemical role
definition: Any minor or unwanted substance introduced into the environment that can have undesired effects.

refrigerant
type: Class
subclass of: application
definition: A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.

alpha-amino acid zwitterion
type: Class
subclass of: amino acid zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino acid
definition: An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3.
charge: 0
formula: C2H4NO2R
mass: 74.059
monoisotopicmass: 74.02420
smiles: [NH3+]C([*])C([O-])=O

carbohydrates and carbohydrate derivatives
type: Class
subclass of: organooxygen compound
definition: Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation.

(R)-nicotinium(1+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: (R)-nicotine
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-nicotinium(1+)
definition: The conjugate acid of (R)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3.
charge: +1
formula: C10H15N2
inchi: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m1/s1
inchikey: SNICXCGAKADSCV-SNVBAGLBSA-O
mass: 163.23900
monoisotopicmass: 163.12297
smiles: C[NH+]1CCC[C@@H]1c1cccnc1

divalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of two.

monovalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of one.

drug allergen
type: Class
subclass of: drug
subclass of: allergen
definition: Any drug which causes the onset of an allergic reaction.

N-sulfonylcarboxamide
type: Class
subclass of: mixed diacylamine
definition: A mixed diacylamine resulting from the formal condensation of the nitrogen of a carboxamide with a sulphonic acid.
charge: 0
formula: CNO3SR3
mass: 106.082
monoisotopicmass: 105.95989
smiles: C(=O)(N(S(*)(=O)=O)*)*

aromatic carboxylate
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: aromatic carboxylic acid
definition: A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3.
charge: -1
formula: CO2R
mass: 44.010
monoisotopicmass: 43.98983
smiles: *C([O-])=O

atom
type: Class
equivalent class: Restriction
  on property: has number of atomic nuclei
  has value: 1
subclass of: material entity
subclass of: Restriction
  on property: has part
  some values from: atomic nucleus
disjoint with: molecular entity
definition: A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it.
comment: This atom is closely related to ChEBI's atom, but not exactly equivalent to.

molecular entity
type: Class
subclass of: material entity
subclass of: Restriction
  on property: has part
  some values from: atom
disjoint with: complex of molecular entities
definition: A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom.
comment: This molecular entity is different than ChEBI's 'molecular entity'.
comment: We would like to have cardinality restrictions on the logic, but there are some technical limitations.

gene product
type: Class
subclass of: molecular entity

complex of molecular entities
type: Class
subclass of: material entity
subclass of: Restriction
definition: A complex of two or more molecular entities that are not covalently bound.

Axiom
annotated source: complex of molecular entities
annotated property: subClassOf
annotated target: Restriction
comment: >=2 parts (not we cannot use cardinality with transitive properties)

reproduction
type: Class
subclass of: biological_process

polysaccharide biosynthetic process
type: Class
subclass of: polysaccharide metabolic process
subclass of: macromolecule biosynthetic process
subclass of: carbohydrate biosynthetic process

polysaccharide catabolic process
type: Class
subclass of: polysaccharide metabolic process
subclass of: macromolecule catabolic process
subclass of: carbohydrate catabolic process

response to acid chemical
type: Class
subclass of: response to chemical
comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.

skeletal system development
type: Class
subclass of: system development

ossification
type: Class
subclass of: multicellular organismal process
comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.

temperature homeostasis
type: Class
subclass of: multicellular organismal-level homeostasis

ameboidal-type cell migration
type: Class
subclass of: cell migration
comment: Note that this term refers to a mode of migration rather than to any particular cell type.

gastric acid secretion
type: Class
subclass of: digestive system process
subclass of: acid secretion

formation of primary germ layer
type: Class
subclass of: anatomical structure formation involved in morphogenesis
subclass of: Restriction
  on property: part of
  some values from: gastrulation

ectoderm formation
type: Class
subclass of: formation of primary germ layer
subclass of: Restriction
  on property: part of
  some values from: ectoderm development

endoderm formation
type: Class
subclass of: formation of primary germ layer
subclass of: Restriction
  on property: part of
  some values from: endoderm development

mesoderm formation
type: Class
subclass of: formation of primary germ layer
subclass of: Restriction
  on property: part of
  some values from: mesoderm morphogenesis

morphogenesis of a branching structure
type: Class
subclass of: anatomical structure morphogenesis
subclass of: multicellular organismal process

serotonin secretion
type: Class
subclass of: serotonin transport
subclass of: signal release

embryonic epithelial tube formation
type: Class
subclass of: epithelial tube formation
subclass of: Restriction
  on property: part of
  some values from: morphogenesis of embryonic epithelium

neural tube formation
type: Class
subclass of: embryonic epithelial tube formation
subclass of: Restriction
  on property: part of
  some values from: neural tube development

intramembranous ossification
type: Class
subclass of: direct ossification
comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.

morphogenesis of an epithelium
type: Class
subclass of: tissue morphogenesis
subclass of: Restriction
  on property: part of
  some values from: epithelium development

regulation of heart rate
type: Class
subclass of: regulation of heart contraction
subclass of: regulation of biological quality

positive regulation of mesenchymal cell proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: mesenchymal cell proliferation
subclass of: positive regulation of cell population proliferation
subclass of: regulation of mesenchymal cell proliferation
subclass of: Restriction
  on property: positively regulates
  some values from: mesenchymal cell proliferation

regulation of respiratory gaseous exchange by nervous system process
type: Class
equivalent class: Class
  intersection of: nervous system process
  intersection of: Restriction
    on property: regulates
    some values from: respiratory gaseous exchange by respiratory system
subclass of: regulation of respiratory system process
subclass of: nervous system process

aggressive behavior
type: Class
subclass of: behavior

nematode larval development
type: Class
subclass of: larval development

obsolete predatory behavior
type: Class
IAO_0000233: https://github.com/geneontology/go-ontology/issues/18568
comment: This term was obsoleted because it is outside the scope of GO.
deprecated: true

larval development
type: Class
subclass of: multicellular organism development
subclass of: post-embryonic development

organ or tissue specific immune response
type: Class
subclass of: immune response

immune system process
type: Class
subclass of: biological_process
RO_0002161: NCBITaxon 4895
comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).

hepatic immune response
type: Class
subclass of: organ or tissue specific immune response

regulation of immune system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: immune system process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: immune system process

negative regulation of immune system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: immune system process
subclass of: regulation of immune system process
subclass of: negative regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: immune system process

positive regulation of immune system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: immune system process
subclass of: regulation of immune system process
subclass of: positive regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: immune system process

peptide secretion
type: Class
subclass of: peptide transport
subclass of: secretion

regulation of peptide secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: peptide secretion
subclass of: regulation of secretion
subclass of: regulation of peptide transport
subclass of: Restriction
  on property: regulates
  some values from: peptide secretion

negative regulation of peptide secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: peptide secretion
subclass of: regulation of peptide secretion
subclass of: negative regulation of secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: peptide secretion

positive regulation of peptide secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: peptide secretion
subclass of: regulation of peptide secretion
subclass of: positive regulation of secretion
subclass of: Restriction
  on property: positively regulates
  some values from: peptide secretion

developmental process involved in reproduction
type: Class
equivalent class: Class
  intersection of: developmental process
  intersection of: Restriction
    on property: part of
    some values from: reproduction
subclass of: reproductive process
subclass of: developmental process

system process
type: Class
subclass of: multicellular organismal process

muscle system process
type: Class
subclass of: system process

circulatory system process
type: Class
subclass of: system process

renal system process
type: Class
subclass of: system process

heart process
type: Class
subclass of: circulatory system process

respiratory system process
type: Class
subclass of: system process
subclass of: Restriction
  on property: part of
  some values from: respiratory gaseous exchange by respiratory system

molecular_function
type: Class
subclass of: process
subclass of: Restriction
  on property: enabled by
  some values from: Class
    union of: gene product
    union of: protein-containing complex
disjoint with: biological_process
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
comment: This is the same as GO molecular function
label: gene product or complex activity

catalytic activity
type: Class
subclass of: molecular_function

cellular_component
type: Class
comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.

extracellular region
type: Class
subclass of: cellular anatomical entity
comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.

fibrinogen complex
type: Class
subclass of: protein-containing complex
subclass of: Restriction
  on property: part of
  some values from: extracellular space

collagen trimer
type: Class
subclass of: protein-containing complex

fibrillar collagen trimer
type: Class
equivalent class: Class
  intersection of: collagen trimer
  intersection of: Restriction
    on property: part of
    some values from: banded collagen fibril
subclass of: collagen trimer
subclass of: Restriction
  on property: part of
  some values from: banded collagen fibril
disjoint with: transmembrane collagen trimer

collagen type II trimer
type: Class
subclass of: fibrillar collagen trimer

collagen type IV trimer
type: Class
subclass of: network-forming collagen trimer
subclass of: basement membrane collagen trimer

basement membrane
type: Class
subclass of: collagen-containing extracellular matrix
comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.

extracellular space
type: Class
subclass of: cellular anatomical entity
subclass of: Restriction
  on property: part of
  some values from: extracellular region
comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.

intracellular anatomical structure
type: Class
subclass of: cellular anatomical entity
IAO_0000233: https://github.com/geneontology/go-ontology/issues/17776

cytoplasm
type: Class
subclass of: cellular anatomical entity
subclass of: Restriction
  on property: part of
  some values from: intracellular anatomical structure
IAO_0000233: https://github.com/geneontology/go-ontology/issues/23023

cytoskeleton
type: Class
subclass of: intracellular non-membrane-bounded organelle

actin filament
type: Class
subclass of: polymeric cytoskeletal fiber
subclass of: Restriction
  on property: part of
  some values from: actin cytoskeleton

plasma membrane
type: Class
subclass of: membrane
subclass of: Restriction
  on property: part of
  some values from: cell periphery

microvillus
type: Class
subclass of: actin-based cell projection
subclass of: Restriction
  on property: has part
  some values from: actin filament bundle
RO_0002161: NCBITaxon 4751
comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta.

cell-cell junction
type: Class
subclass of: anchoring junction
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22122

cell cortex
type: Class
equivalent class: Class
  intersection of: cytoplasm
  intersection of: Restriction
    on property: part of
    some values from: cell periphery
subclass of: cytoplasm
subclass of: Restriction
  on property: part of
  some values from: cell periphery

carbohydrate metabolic process
type: Class
subclass of: primary metabolic process
subclass of: organic substance metabolic process
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22880

polysaccharide metabolic process
type: Class
subclass of: carbohydrate metabolic process
subclass of: macromolecule metabolic process

glycogen metabolic process
type: Class
subclass of: energy reserve metabolic process
subclass of: glucan metabolic process

glycogen biosynthetic process
type: Class
subclass of: glycogen metabolic process
subclass of: glucan biosynthetic process

regulation of glycogen biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glycogen biosynthetic process
subclass of: regulation of glucan biosynthetic process
subclass of: regulation of glycogen metabolic process
subclass of: Restriction
  on property: regulates
  some values from: glycogen biosynthetic process

glycogen catabolic process
type: Class
subclass of: glycogen metabolic process
subclass of: glucan catabolic process

regulation of glycogen catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glycogen catabolic process
subclass of: regulation of carbohydrate catabolic process
subclass of: regulation of glycogen metabolic process
subclass of: Restriction
  on property: regulates
  some values from: glycogen catabolic process

monosaccharide metabolic process
type: Class
subclass of: carbohydrate metabolic process
subclass of: small molecule metabolic process

glucose metabolic process
type: Class
subclass of: hexose metabolic process

organic acid metabolic process
type: Class
subclass of: cellular metabolic process
subclass of: small molecule metabolic process
subclass of: organic substance metabolic process

generation of precursor metabolites and energy
type: Class
subclass of: cellular metabolic process

regulation of carbohydrate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: carbohydrate metabolic process
subclass of: regulation of primary metabolic process
subclass of: Restriction
  on property: regulates
  some values from: carbohydrate metabolic process

energy reserve metabolic process
type: Class
subclass of: energy derivation by oxidation of organic compounds

lipid metabolic process
type: Class
subclass of: primary metabolic process
subclass of: organic substance metabolic process

steroid biosynthetic process
type: Class
subclass of: steroid metabolic process
subclass of: lipid biosynthetic process
subclass of: organic cyclic compound biosynthetic process

bile acid biosynthetic process
type: Class
subclass of: steroid biosynthetic process
subclass of: bile acid metabolic process
subclass of: monocarboxylic acid biosynthetic process
subclass of: organic hydroxy compound biosynthetic process

phosphorus metabolic process
type: Class
subclass of: cellular metabolic process

phosphate-containing compound metabolic process
type: Class
subclass of: phosphorus metabolic process

transport
type: Class
subclass of: establishment of localization
IAO_0000233: https://github.com/geneontology/go-ontology/issues/20292
comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.

monoatomic ion transport
type: Class
subclass of: transport

serotonin transport
type: Class
subclass of: monoamine transport
subclass of: organic hydroxy compound transport

extracellular transport
type: Class
equivalent class: Class
  intersection of: transport
  intersection of: Restriction
    on property: occurs in
    some values from: extracellular region
subclass of: transport
subclass of: Restriction
  on property: occurs in
  some values from: extracellular region

lipid transport
type: Class
subclass of: organic substance transport
subclass of: Restriction
  on property: part of
  some values from: lipid localization

intracellular protein transport
type: Class
subclass of: protein transport
subclass of: intracellular transport
subclass of: Restriction
  on property: part of
  some values from: protein localization

muscle contraction
type: Class
subclass of: muscle system process

regulation of muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: muscle contraction
subclass of: regulation of muscle system process
subclass of: Restriction
  on property: regulates
  some values from: muscle contraction

smooth muscle contraction
type: Class
subclass of: muscle contraction

regulation of smooth muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: smooth muscle contraction
subclass of: regulation of muscle contraction
subclass of: Restriction
  on property: regulates
  some values from: smooth muscle contraction

response to stress
type: Class
subclass of: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

immune response
type: Class
subclass of: immune system process
subclass of: response to stimulus

cell communication
type: Class
subclass of: cellular process

cell-cell signaling
type: Class
subclass of: cell communication
subclass of: signaling

multicellular organism development
type: Class
subclass of: multicellular organismal process
subclass of: anatomical structure development
IAO_0000233: https://github.com/geneontology/go-ontology/issues/21234
comment: Note that this term was 'developmental process'.

gamete generation
type: Class
subclass of: multicellular organismal reproductive process
subclass of: Restriction
  on property: part of
  some values from: sexual reproduction
RO_0002161: NCBITaxon Union 0000023

gastrulation
type: Class
subclass of: embryonic morphogenesis
subclass of: Restriction
  on property: has part
  some values from: ectoderm formation
subclass of: Restriction
  on property: has part
  some values from: endoderm formation
subclass of: Restriction
  on property: has part
  some values from: mesoderm formation

ectoderm development
type: Class
subclass of: tissue development

nervous system development
type: Class
subclass of: system development

endoderm development
type: Class
subclass of: tissue development

mesoderm development
type: Class
subclass of: tissue development

respiratory gaseous exchange by respiratory system
type: Class
subclass of: multicellular organismal process

digestion
type: Class
subclass of: multicellular organismal process

excretion
type: Class
subclass of: system process
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22368

body fluid secretion
type: Class
subclass of: secretion
subclass of: regulation of body fluid levels

sensory perception
type: Class
subclass of: nervous system process

visual perception
type: Class
subclass of: sensory perception of light stimulus

sensory perception of sound
type: Class
subclass of: sensory perception of mechanical stimulus

sensory perception of chemical stimulus
type: Class
subclass of: sensory perception

sensory perception of smell
type: Class
subclass of: sensory perception of chemical stimulus

behavior
type: Class
subclass of: multicellular organismal process
disjoint with: developmental process
comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).

mating behavior
type: Class
subclass of: reproductive behavior

courtship behavior
type: Class
subclass of: mating behavior

copulation
type: Class
subclass of: mating behavior

rhythmic behavior
type: Class
subclass of: behavior

circadian rhythm
type: Class
subclass of: rhythmic process

grooming behavior
type: Class
subclass of: behavior
has exact synonym: groom

locomotory behavior
type: Class
subclass of: behavior

flight behavior
type: Class
subclass of: adult locomotory behavior
has exact synonym: fly

feeding behavior
type: Class
subclass of: behavior
IAO_0000233: https://github.com/geneontology/go-ontology/issues/18547
comment: See also the biological process term 'behavior ; GO:0007610'.

visual behavior
type: Class
subclass of: behavior
subclass of: response to light stimulus

chemosensory behavior
type: Class
subclass of: behavior
subclass of: Restriction
  on property: part of
  some values from: response to chemical

mechanosensory behavior
type: Class
subclass of: behavior
subclass of: Restriction
  on property: part of
  some values from: response to mechanical stimulus

blood circulation
type: Class
subclass of: circulatory system process

regulation of heart contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: heart contraction
subclass of: regulation of blood circulation
subclass of: Restriction
  on property: regulates
  some values from: heart contraction

male courtship behavior
type: Class
subclass of: courtship behavior
subclass of: male mating behavior

female courtship behavior
type: Class
subclass of: courtship behavior
subclass of: female mating behavior

protein localization
type: Class
subclass of: cellular macromolecule localization
IAO_0000233: https://github.com/geneontology/go-ontology/issues/23112

biological_process
type: Class
subclass of: process
subclass of: Restriction
  on property: has part
  some values from: molecular_function
definition: A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective.
IAO_0000233: https://github.com/geneontology/go-ontology/issues/24968
comment: A biological process is an evolved process
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
label: biological process

metabolic process
type: Class
subclass of: biological_process
disjoint with: localization
comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.

steroid metabolic process
type: Class
subclass of: lipid metabolic process
subclass of: organic cyclic compound metabolic process

bile acid metabolic process
type: Class
subclass of: steroid metabolic process
subclass of: monocarboxylic acid metabolic process
subclass of: organic hydroxy compound metabolic process

cell population proliferation
type: Class
subclass of: cellular process
RO_0002161: NCBITaxon 4751
comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.

positive regulation of cell population proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cell population proliferation
subclass of: regulation of cell population proliferation
subclass of: positive regulation of cellular process
subclass of: Restriction
  on property: positively regulates
  some values from: cell population proliferation
RO_0002161: NCBITaxon 4751

negative regulation of cell population proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cell population proliferation
subclass of: regulation of cell population proliferation
subclass of: negative regulation of cellular process
subclass of: Restriction
  on property: negatively regulates
  some values from: cell population proliferation
RO_0002161: NCBITaxon 4751

adult locomotory behavior
type: Class
subclass of: locomotory behavior
subclass of: adult behavior
comment: See also the biological process term 'locomotory behavior ; GO:0007626'.

lipid biosynthetic process
type: Class
subclass of: lipid metabolic process
subclass of: organic substance biosynthetic process

catabolic process
type: Class
subclass of: metabolic process

macromolecule catabolic process
type: Class
subclass of: macromolecule metabolic process
subclass of: organic substance catabolic process

biosynthetic process
type: Class
subclass of: metabolic process

macromolecule biosynthetic process
type: Class
subclass of: macromolecule metabolic process
subclass of: organic substance biosynthetic process
IAO_0000233: http://amigo.geneontology.org/amigo/term/GO:0070589

glucan biosynthetic process
type: Class
subclass of: polysaccharide biosynthetic process
subclass of: glucan metabolic process

glucan catabolic process
type: Class
subclass of: polysaccharide catabolic process
subclass of: glucan metabolic process

response to temperature stimulus
type: Class
subclass of: response to abiotic stimulus

protein secretion
type: Class
subclass of: protein transport
subclass of: secretion by cell
subclass of: establishment of protein localization to extracellular region

response to radiation
type: Class
subclass of: response to abiotic stimulus
comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength.

response to water deprivation
type: Class
subclass of: response to stress
subclass of: response to water

response to water
type: Class
subclass of: response to acid chemical
subclass of: response to abiotic stimulus
subclass of: response to organic substance
subclass of: response to inorganic substance
subclass of: response to oxygen-containing compound
subclass of: response to salt

response to light stimulus
type: Class
subclass of: response to radiation

detection of external stimulus
type: Class
subclass of: response to external stimulus
subclass of: detection of stimulus

detection of abiotic stimulus
type: Class
subclass of: response to abiotic stimulus
subclass of: detection of stimulus

detection of light stimulus
type: Class
subclass of: response to light stimulus
subclass of: detection of external stimulus
subclass of: detection of abiotic stimulus

detection of visible light
type: Class
subclass of: detection of light stimulus

detection of chemical stimulus
type: Class
subclass of: detection of stimulus
subclass of: Restriction
  on property: part of
  some values from: response to chemical

response to external stimulus
type: Class
subclass of: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

response to mechanical stimulus
type: Class
subclass of: response to external stimulus
subclass of: response to abiotic stimulus

response to abiotic stimulus
type: Class
subclass of: response to stimulus
IAO_0000233: https://github.com/geneontology/go-ontology/issues/16572
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

anatomical structure morphogenesis
type: Class
subclass of: developmental process
subclass of: Restriction
  on property: part of
  some values from: anatomical structure development

embryo development
type: Class
subclass of: multicellular organism development

post-embryonic development
type: Class
subclass of: multicellular organismal process
subclass of: Restriction
  on property: part of
  some values from: multicellular organism development

embryo development ending in birth or egg hatching
type: Class
subclass of: embryo development

tissue development
type: Class
subclass of: anatomical structure development
RO_0002161: NCBITaxon_147554
RO_0002161: NCBITaxon_33630
RO_0002161: NCBITaxon_33682
RO_0002161: NCBITaxon_38254
RO_0002161: NCBITaxon 4891

regulation of biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: biosynthetic process
subclass of: regulation of metabolic process
subclass of: Restriction
  on property: regulates
  some values from: biosynthetic process

negative regulation of biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: biosynthetic process
subclass of: regulation of biosynthetic process
subclass of: negative regulation of metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: biosynthetic process

positive regulation of biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: biosynthetic process
subclass of: regulation of biosynthetic process
subclass of: positive regulation of metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: biosynthetic process

negative regulation of metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: metabolic process
subclass of: regulation of metabolic process
subclass of: negative regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: metabolic process

positive regulation of metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: metabolic process
subclass of: regulation of metabolic process
subclass of: positive regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: metabolic process

regulation of catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: catabolic process
subclass of: regulation of metabolic process
subclass of: Restriction
  on property: regulates
  some values from: catabolic process

negative regulation of catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: catabolic process
subclass of: negative regulation of metabolic process
subclass of: regulation of catabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: catabolic process

positive regulation of catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: catabolic process
subclass of: positive regulation of metabolic process
subclass of: regulation of catabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: catabolic process

hormone transport
type: Class
subclass of: transport
subclass of: regulation of hormone levels

cellular process
type: Class
subclass of: biological_process
comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.

response to organic substance
type: Class
subclass of: response to chemical

response to inorganic substance
type: Class
subclass of: response to chemical

mesenchymal cell proliferation
type: Class
subclass of: cell population proliferation

regulation of mesenchymal cell proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: mesenchymal cell proliferation
subclass of: regulation of cell population proliferation
subclass of: Restriction
  on property: regulates
  some values from: mesenchymal cell proliferation

regulation of gastrulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: gastrulation
subclass of: regulation of anatomical structure morphogenesis
subclass of: regulation of embryonic development
subclass of: Restriction
  on property: regulates
  some values from: gastrulation

regulation of macromolecule biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: macromolecule biosynthetic process
subclass of: regulation of biosynthetic process
subclass of: regulation of macromolecule metabolic process
subclass of: Restriction
  on property: regulates
  some values from: macromolecule biosynthetic process

positive regulation of macromolecule biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: macromolecule biosynthetic process
subclass of: positive regulation of biosynthetic process
subclass of: regulation of macromolecule biosynthetic process
subclass of: positive regulation of macromolecule metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: macromolecule biosynthetic process

negative regulation of macromolecule biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: macromolecule biosynthetic process
subclass of: negative regulation of biosynthetic process
subclass of: regulation of macromolecule biosynthetic process
subclass of: negative regulation of macromolecule metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: macromolecule biosynthetic process

positive regulation of phosphorus metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: phosphorus metabolic process
subclass of: positive regulation of cellular metabolic process
subclass of: regulation of phosphorus metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: phosphorus metabolic process

negative regulation of phosphorus metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: phosphorus metabolic process
subclass of: negative regulation of cellular metabolic process
subclass of: regulation of phosphorus metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: phosphorus metabolic process

regulation of cellular ketone metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular ketone metabolic process
subclass of: regulation of cellular metabolic process
subclass of: regulation of small molecule metabolic process
subclass of: Restriction
  on property: regulates
  some values from: cellular ketone metabolic process

positive regulation of macromolecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: macromolecule metabolic process
subclass of: positive regulation of metabolic process
subclass of: regulation of macromolecule metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: macromolecule metabolic process

negative regulation of macromolecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: macromolecule metabolic process
subclass of: negative regulation of metabolic process
subclass of: regulation of macromolecule metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: macromolecule metabolic process

regulation of cell communication
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cell communication
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cell communication

positive regulation of cell communication
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cell communication
subclass of: regulation of cell communication
subclass of: positive regulation of cellular process
subclass of: Restriction
  on property: positively regulates
  some values from: cell communication

negative regulation of cell communication
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cell communication
subclass of: regulation of cell communication
subclass of: negative regulation of cellular process
subclass of: Restriction
  on property: negatively regulates
  some values from: cell communication

negative regulation of norepinephrine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: norepinephrine secretion
subclass of: regulation of norepinephrine secretion
subclass of: negative regulation of catecholamine secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: norepinephrine secretion

positive regulation of norepinephrine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: norepinephrine secretion
subclass of: regulation of norepinephrine secretion
subclass of: positive regulation of catecholamine secretion
subclass of: Restriction
  on property: positively regulates
  some values from: norepinephrine secretion

regulation of hormone levels
type: Class
subclass of: regulation of biological quality

lipid localization
type: Class
subclass of: macromolecule localization

positive regulation of steroid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: steroid biosynthetic process
subclass of: positive regulation of steroid metabolic process
subclass of: positive regulation of lipid biosynthetic process
subclass of: regulation of steroid biosynthetic process
subclass of: Restriction
  on property: positively regulates
  some values from: steroid biosynthetic process

negative regulation of steroid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: steroid biosynthetic process
subclass of: negative regulation of steroid metabolic process
subclass of: regulation of steroid biosynthetic process
subclass of: negative regulation of lipid biosynthetic process
subclass of: Restriction
  on property: negatively regulates
  some values from: steroid biosynthetic process

regulation of glucose metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glucose metabolic process
subclass of: regulation of carbohydrate metabolic process
subclass of: regulation of small molecule metabolic process
subclass of: Restriction
  on property: regulates
  some values from: glucose metabolic process

positive regulation of glucose metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: glucose metabolic process
subclass of: regulation of glucose metabolic process
subclass of: positive regulation of carbohydrate metabolic process
subclass of: positive regulation of small molecule metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: glucose metabolic process

regulation of glucan biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glucan biosynthetic process
subclass of: regulation of polysaccharide biosynthetic process
subclass of: Restriction
  on property: regulates
  some values from: glucan biosynthetic process

response to auditory stimulus
type: Class
subclass of: response to mechanical stimulus

vesicle membrane
type: Class
equivalent class: Class
  intersection of: membrane
  intersection of: Restriction
    on property: part of
    some values from: vesicle
subclass of: organelle membrane
subclass of: Restriction
  on property: part of
  some values from: vesicle

regulation of norepinephrine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: norepinephrine secretion
subclass of: regulation of catecholamine secretion
subclass of: Restriction
  on property: regulates
  some values from: norepinephrine secretion

regulation of serotonin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: serotonin secretion
subclass of: regulation of monoatomic ion transport
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: regulates
  some values from: serotonin secretion

negative regulation of serotonin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: serotonin secretion
subclass of: regulation of serotonin secretion
subclass of: negative regulation of monoatomic ion transport
subclass of: negative regulation of secretion by cell
subclass of: Restriction
  on property: negatively regulates
  some values from: serotonin secretion

positive regulation of serotonin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: serotonin secretion
subclass of: regulation of serotonin secretion
subclass of: positive regulation of monoatomic ion transport
subclass of: positive regulation of secretion by cell
subclass of: Restriction
  on property: positively regulates
  some values from: serotonin secretion

phasic smooth muscle contraction
type: Class
subclass of: smooth muscle contraction

urinary bladder smooth muscle contraction
type: Class
subclass of: urinary tract smooth muscle contraction
RO_0002161: NCBITaxon 8782

urinary tract smooth muscle contraction
type: Class
subclass of: smooth muscle contraction

protein transport
type: Class
subclass of: establishment of protein localization
subclass of: organic substance transport
subclass of: nitrogen compound transport

actin cytoskeleton
type: Class
subclass of: cytoskeleton

organic cation transport
type: Class
subclass of: organic substance transport

organic anion transport
type: Class
subclass of: organic substance transport

monocarboxylic acid transport
type: Class
subclass of: carboxylic acid transport

bile acid and bile salt transport
type: Class
subclass of: lipid transport
subclass of: monocarboxylic acid transport
subclass of: organic hydroxy compound transport

peptide transport
type: Class
subclass of: amide transport
subclass of: organic substance transport

amine transport
type: Class
subclass of: organic substance transport
subclass of: nitrogen compound transport

monoamine transport
type: Class
subclass of: organic substance transport
subclass of: nitrogen compound transport

organic acid transport
type: Class
subclass of: organic substance transport

organic hydroxy compound transport
type: Class
subclass of: organic substance transport

norepinephrine transport
type: Class
subclass of: organic cation transport
subclass of: catecholamine transport

energy derivation by oxidation of organic compounds
type: Class
subclass of: generation of precursor metabolites and energy

membrane
type: Class
subclass of: cellular anatomical entity

cellular component organization
type: Class
subclass of: cellular component organization or biogenesis

detection of temperature stimulus
type: Class
subclass of: response to temperature stimulus
subclass of: detection of external stimulus
subclass of: detection of abiotic stimulus

carbohydrate biosynthetic process
type: Class
subclass of: carbohydrate metabolic process
subclass of: organic substance biosynthetic process

carbohydrate catabolic process
type: Class
subclass of: carbohydrate metabolic process
subclass of: organic substance catabolic process

organic acid biosynthetic process
type: Class
subclass of: organic acid metabolic process
subclass of: cellular biosynthetic process
subclass of: small molecule biosynthetic process
subclass of: organic substance biosynthetic process

kinase activity
type: Class
subclass of: transferase activity, transferring phosphorus-containing groups
subclass of: Restriction
  on property: is kinase activity
  has self: true
comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.

phosphorylation
type: Class
subclass of: phosphate-containing compound metabolic process

morphogenesis of embryonic epithelium
type: Class
subclass of: morphogenesis of an epithelium
subclass of: embryonic morphogenesis

cell migration
type: Class
subclass of: cell motility
IAO_0000233: https://github.com/geneontology/go-ontology/issues/24787

transferase activity
type: Class
subclass of: catalytic activity

transferase activity, transferring phosphorus-containing groups
type: Class
subclass of: transferase activity
comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.

reproductive behavior
type: Class
equivalent class: Class
  intersection of: behavior
  intersection of: Restriction
    on property: part of
    some values from: multicellular organism reproduction
subclass of: behavior
subclass of: reproductive process
subclass of: Restriction
  on property: part of
  some values from: multicellular organism reproduction
IAO_0000233: https://github.com/geneontology/go-ontology/issues/23491

regulation of lipid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: lipid metabolic process
subclass of: regulation of primary metabolic process
subclass of: Restriction
  on property: regulates
  some values from: lipid metabolic process

regulation of steroid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: steroid metabolic process
subclass of: regulation of lipid metabolic process
subclass of: Restriction
  on property: regulates
  some values from: steroid metabolic process

regulation of phosphate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: phosphate-containing compound metabolic process
subclass of: regulation of phosphorus metabolic process
subclass of: Restriction
  on property: regulates
  some values from: phosphate-containing compound metabolic process

regulation of metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: metabolic process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: metabolic process

sensory perception of pain
type: Class
subclass of: sensory perception

hexose metabolic process
type: Class
subclass of: monosaccharide metabolic process

carboxylic acid metabolic process
type: Class
subclass of: oxoacid metabolic process

sexual reproduction
type: Class
subclass of: reproduction
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22929
comment: Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.

neural tube development
type: Class
subclass of: tube development
subclass of: epithelium development
subclass of: Restriction
  on property: part of
  some values from: nervous system development
subclass of: Restriction
  on property: part of
  some values from: chordate embryonic development

circadian sleep/wake cycle process
type: Class
subclass of: circadian behavior
subclass of: Restriction
  on property: part of
  some values from: circadian sleep/wake cycle

cellular process involved in reproduction in multicellular organism
type: Class
equivalent class: Class
  intersection of: cellular process
  intersection of: Restriction
    on property: part of
    some values from: multicellular organism reproduction
subclass of: cellular process
subclass of: reproductive process
subclass of: Restriction
  on property: part of
  some values from: multicellular organism reproduction

reproductive process
type: Class
equivalent class: Class
  intersection of: biological_process
  intersection of: Restriction
    on property: part of
    some values from: reproduction
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: reproduction

digestive system process
type: Class
equivalent class: Class
  intersection of: system process
  intersection of: Restriction
    on property: part of
    some values from: digestion
subclass of: system process
subclass of: Restriction
  on property: part of
  some values from: digestion

regulation of anatomical structure morphogenesis
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: anatomical structure morphogenesis
subclass of: regulation of developmental process
subclass of: Restriction
  on property: regulates
  some values from: anatomical structure morphogenesis

regulation of signaling
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: signaling
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: signaling

signaling
type: Class
subclass of: regulation of biological process
comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.

positive regulation of signaling
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: signaling
subclass of: regulation of signaling
subclass of: positive regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: signaling

negative regulation of signaling
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: signaling
subclass of: regulation of signaling
subclass of: negative regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: signaling

signal release
type: Class
equivalent class: Class
  intersection of: secretion by cell
  intersection of: Restriction
    on property: part of
    some values from: cell-cell signaling
subclass of: secretion by cell
subclass of: Restriction
  on property: part of
  some values from: cell-cell signaling

cell junction
type: Class
subclass of: cellular anatomical entity
RO_0002161: NCBITaxon 4751

peptide hormone secretion
type: Class
subclass of: peptide secretion
subclass of: hormone secretion

insulin secretion
type: Class
subclass of: protein secretion
subclass of: peptide hormone secretion
IAO_0000233: https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045

regulation of ossification
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: ossification
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: ossification

negative regulation of ossification
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: ossification
subclass of: regulation of ossification
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: ossification

external encapsulating structure
type: Class
subclass of: cellular anatomical entity
subclass of: Restriction
  on property: part of
  some values from: cell periphery
comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.

regulation of cell migration
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cell migration
subclass of: regulation of cell motility
subclass of: Restriction
  on property: regulates
  some values from: cell migration

positive regulation of cell migration
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cell migration
subclass of: regulation of cell migration
subclass of: positive regulation of cell motility
subclass of: Restriction
  on property: positively regulates
  some values from: cell migration

negative regulation of cell migration
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cell migration
subclass of: regulation of cell migration
subclass of: negative regulation of cell motility
subclass of: Restriction
  on property: negatively regulates
  some values from: cell migration

defecation
type: Class
subclass of: excretion
subclass of: digestive system process

sleep
type: Class
subclass of: multicellular organismal process

peristalsis
type: Class
subclass of: phasic smooth muscle contraction

adult behavior
type: Class
subclass of: behavior
comment: See also the biological process term 'behavior ; GO:0007610'.

cytoplasmic vesicle membrane
type: Class
equivalent class: Class
  intersection of: membrane
  intersection of: Restriction
    on property: part of
    some values from: cytoplasmic vesicle
subclass of: vesicle membrane
subclass of: Restriction
  on property: part of
  some values from: cytoplasmic vesicle

transmembrane collagen trimer
type: Class
equivalent class: Class
  intersection of: collagen trimer
  intersection of: Restriction
    on property: part of
    some values from: plasma membrane
subclass of: collagen trimer
subclass of: plasma membrane protein complex

extracellular matrix
type: Class
subclass of: external encapsulating structure

organelle membrane
type: Class
equivalent class: Class
  intersection of: membrane
  intersection of: Restriction
    on property: part of
    some values from: membrane-bounded organelle
subclass of: membrane
subclass of: Restriction
  on property: part of
  some values from: membrane-bounded organelle

auditory behavior
type: Class
subclass of: mechanosensory behavior
subclass of: Restriction
  on property: part of
  some values from: response to auditory stimulus

regulation of cellular metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular metabolic process
subclass of: regulation of metabolic process
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cellular metabolic process

negative regulation of cellular metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cellular metabolic process
subclass of: negative regulation of metabolic process
subclass of: regulation of cellular metabolic process
subclass of: negative regulation of cellular process
subclass of: Restriction
  on property: negatively regulates
  some values from: cellular metabolic process

positive regulation of cellular metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cellular metabolic process
subclass of: positive regulation of metabolic process
subclass of: regulation of cellular metabolic process
subclass of: positive regulation of cellular process
subclass of: Restriction
  on property: positively regulates
  some values from: cellular metabolic process

regulation of cellular biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular biosynthetic process
subclass of: regulation of biosynthetic process
subclass of: regulation of cellular metabolic process
subclass of: Restriction
  on property: regulates
  some values from: cellular biosynthetic process

negative regulation of cellular biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cellular biosynthetic process
subclass of: negative regulation of biosynthetic process
subclass of: negative regulation of cellular metabolic process
subclass of: regulation of cellular biosynthetic process
subclass of: Restriction
  on property: negatively regulates
  some values from: cellular biosynthetic process

positive regulation of cellular biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cellular biosynthetic process
subclass of: positive regulation of biosynthetic process
subclass of: positive regulation of cellular metabolic process
subclass of: regulation of cellular biosynthetic process
subclass of: Restriction
  on property: positively regulates
  some values from: cellular biosynthetic process

regulation of cellular catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular catabolic process
subclass of: regulation of catabolic process
subclass of: regulation of cellular metabolic process
subclass of: Restriction
  on property: regulates
  some values from: cellular catabolic process

negative regulation of cellular catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cellular catabolic process
subclass of: negative regulation of catabolic process
subclass of: negative regulation of cellular metabolic process
subclass of: regulation of cellular catabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: cellular catabolic process

positive regulation of cellular catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cellular catabolic process
subclass of: positive regulation of catabolic process
subclass of: positive regulation of cellular metabolic process
subclass of: regulation of cellular catabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: cellular catabolic process

cytoplasmic vesicle
type: Class
equivalent class: Class
  intersection of: vesicle
  intersection of: Restriction
    on property: part of
    some values from: cytoplasm
subclass of: intracellular vesicle
subclass of: Restriction
  on property: part of
  some values from: cytoplasm

regulation of nervous system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: nervous system process
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: nervous system process

negative regulation of nervous system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: nervous system process
subclass of: regulation of nervous system process
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: nervous system process

positive regulation of nervous system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: nervous system process
subclass of: regulation of nervous system process
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: nervous system process

vesicle
type: Class
subclass of: membrane-bounded organelle

locomotion involved in locomotory behavior
type: Class
equivalent class: Class
  intersection of: locomotion
  intersection of: Restriction
    on property: part of
    some values from: locomotory behavior
subclass of: locomotion
subclass of: Restriction
  on property: part of
  some values from: locomotory behavior

positive regulation of insulin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: insulin secretion
subclass of: positive regulation of protein secretion
subclass of: regulation of insulin secretion
subclass of: positive regulation of peptide hormone secretion
subclass of: Restriction
  on property: positively regulates
  some values from: insulin secretion

regulation of response to external stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: response to external stimulus
subclass of: regulation of response to stimulus
subclass of: Restriction
  on property: regulates
  some values from: response to external stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

negative regulation of response to external stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: response to external stimulus
subclass of: regulation of response to external stimulus
subclass of: negative regulation of response to stimulus
subclass of: Restriction
  on property: negatively regulates
  some values from: response to external stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

positive regulation of response to external stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: response to external stimulus
subclass of: regulation of response to external stimulus
subclass of: positive regulation of response to stimulus
subclass of: Restriction
  on property: positively regulates
  some values from: response to external stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

regulation of lipid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: lipid transport
subclass of: regulation of transport
subclass of: regulation of lipid localization
subclass of: Restriction
  on property: regulates
  some values from: lipid transport

negative regulation of lipid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: lipid transport
subclass of: regulation of lipid transport
subclass of: negative regulation of transport
subclass of: negative regulation of lipid localization
subclass of: Restriction
  on property: negatively regulates
  some values from: lipid transport

positive regulation of lipid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: lipid transport
subclass of: regulation of lipid transport
subclass of: positive regulation of transport
subclass of: positive regulation of lipid localization
subclass of: Restriction
  on property: positively regulates
  some values from: lipid transport

regulation of intracellular transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: intracellular transport
subclass of: regulation of transport
subclass of: regulation of cellular localization
subclass of: Restriction
  on property: regulates
  some values from: intracellular transport

negative regulation of intracellular transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: intracellular transport
subclass of: regulation of intracellular transport
subclass of: negative regulation of cellular process
subclass of: negative regulation of transport
subclass of: Restriction
  on property: negatively regulates
  some values from: intracellular transport

positive regulation of intracellular transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: intracellular transport
subclass of: regulation of intracellular transport
subclass of: positive regulation of cellular process
subclass of: positive regulation of transport
subclass of: Restriction
  on property: positively regulates
  some values from: intracellular transport

actin filament bundle
type: Class
subclass of: cellular anatomical entity
subclass of: Restriction
  on property: part of
  some values from: actin cytoskeleton
subclass of: Restriction
  on property: has part
  some values from: actin filament

multicellular organismal process
type: Class
subclass of: biological_process
RO_0002161: NCBITaxon 2
RO_0002161: NCBITaxon 2157
RO_0002161: NCBITaxon 4896
RO_0002161: NCBITaxon 4932

developmental process
type: Class
subclass of: biological_process

multicellular organism reproduction
type: Class
subclass of: reproduction
subclass of: multicellular organismal process

protein transport within lipid bilayer
type: Class
equivalent class: Class
  intersection of: protein transport
  intersection of: Restriction
    on property: occurs in
    some values from: membrane
subclass of: intracellular protein transport
subclass of: membrane organization
subclass of: Restriction
  on property: occurs in
  some values from: membrane

monocarboxylic acid metabolic process
type: Class
subclass of: carboxylic acid metabolic process

plasma membrane bounded cell projection cytoplasm
type: Class
equivalent class: Class
  intersection of: cytoplasm
  intersection of: Restriction
    on property: part of
    some values from: plasma membrane bounded cell projection
subclass of: cytoplasmic region
subclass of: Restriction
  on property: part of
  some values from: plasma membrane bounded cell projection

regulation of localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: localization
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: localization

regulation of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: protein localization
subclass of: regulation of cellular localization
subclass of: Restriction
  on property: regulates
  some values from: protein localization
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22021

regulation of polysaccharide metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: polysaccharide metabolic process
subclass of: regulation of carbohydrate metabolic process
subclass of: regulation of macromolecule metabolic process
subclass of: Restriction
  on property: regulates
  some values from: polysaccharide metabolic process

regulation of polysaccharide biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: polysaccharide biosynthetic process
subclass of: regulation of macromolecule biosynthetic process
subclass of: regulation of polysaccharide metabolic process
subclass of: regulation of carbohydrate biosynthetic process
subclass of: Restriction
  on property: regulates
  some values from: polysaccharide biosynthetic process

regulation of organic acid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: organic acid transport
subclass of: regulation of transport
subclass of: Restriction
  on property: regulates
  some values from: organic acid transport

negative regulation of organic acid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: organic acid transport
subclass of: regulation of organic acid transport
subclass of: negative regulation of transport
subclass of: Restriction
  on property: negatively regulates
  some values from: organic acid transport

positive regulation of organic acid transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: organic acid transport
subclass of: regulation of organic acid transport
subclass of: positive regulation of transport
subclass of: Restriction
  on property: positively regulates
  some values from: organic acid transport

secretion by cell
type: Class
subclass of: secretion
subclass of: export from cell

secretion by tissue
type: Class
subclass of: multicellular organismal process
subclass of: secretion

protein-containing complex
type: Class
subclass of: complex of molecular entities
subclass of: cellular_component
subclass of: Restriction
  on property: has part
  some values from: gene product
comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
comment: This is not covalently bonded, which conflicts with changes to the parent definition.
label: protein-containing macromolecular complex

macromolecule localization
type: Class
subclass of: localization

regulation of intracellular protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: intracellular protein transport
subclass of: regulation of intracellular transport
subclass of: regulation of protein transport
subclass of: Restriction
  on property: regulates
  some values from: intracellular protein transport

negative regulation of catecholamine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: catecholamine secretion
subclass of: regulation of catecholamine secretion
subclass of: negative regulation of amine transport
subclass of: negative regulation of secretion by cell
subclass of: Restriction
  on property: negatively regulates
  some values from: catecholamine secretion

positive regulation of catecholamine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: catecholamine secretion
subclass of: regulation of catecholamine secretion
subclass of: positive regulation of amine transport
subclass of: positive regulation of secretion by cell
subclass of: Restriction
  on property: positively regulates
  some values from: catecholamine secretion

negative regulation of kinase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: kinase activity
subclass of: negative regulation of phosphorylation
subclass of: regulation of kinase activity
subclass of: negative regulation of transferase activity
subclass of: Restriction
  on property: negatively regulates
  some values from: kinase activity

positive regulation of kinase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: kinase activity
subclass of: positive regulation of phosphorylation
subclass of: regulation of kinase activity
subclass of: positive regulation of transferase activity
subclass of: Restriction
  on property: positively regulates
  some values from: kinase activity

tube formation
type: Class
subclass of: anatomical structure formation involved in morphogenesis
subclass of: Restriction
  on property: part of
  some values from: tube morphogenesis

social behavior
type: Class
subclass of: behavior
subclass of: biological process involved in intraspecies interaction between organisms
comment: Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.

tube morphogenesis
type: Class
subclass of: anatomical structure morphogenesis
subclass of: Restriction
  on property: part of
  some values from: tube development

tube development
type: Class
subclass of: anatomical structure development
subclass of: Restriction
  on property: part of
  some values from: multicellular organism development

establishment of protein localization to extracellular region
type: Class
subclass of: establishment of protein localization
subclass of: protein localization to extracellular region

regulation of urine volume
type: Class
subclass of: renal system process
subclass of: regulation of body fluid levels

direct ossification
type: Class
subclass of: ossification

somatodendritic compartment
type: Class
subclass of: cellular anatomical entity

locomotion
type: Class
subclass of: biological_process
RO_0002161: NCBITaxon_451864

regulation of locomotion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: locomotion
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: locomotion

negative regulation of locomotion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: locomotion
subclass of: regulation of locomotion
subclass of: negative regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: locomotion

embryonic cleavage
type: Class
subclass of: cell division
subclass of: Restriction
  on property: part of
  some values from: embryo development

positive regulation of locomotion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: locomotion
subclass of: regulation of locomotion
subclass of: positive regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: locomotion

positive regulation of embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: embryo development
subclass of: regulation of embryonic development
subclass of: positive regulation of developmental process
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: embryo development

cell migration involved in gastrulation
type: Class
equivalent class: Class
  intersection of: cell migration
  intersection of: Restriction
    on property: part of
    some values from: gastrulation
subclass of: ameboidal-type cell migration
subclass of: Restriction
  on property: part of
  some values from: gastrulation

regulation of cell population proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cell population proliferation
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cell population proliferation
RO_0002161: NCBITaxon 4751

cellular ketone metabolic process
type: Class
subclass of: cellular metabolic process
subclass of: small molecule metabolic process
subclass of: organic substance metabolic process

response to chemical
type: Class
subclass of: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

regulation of circadian sleep/wake cycle, REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: circadian sleep/wake cycle, REM sleep
subclass of: regulation of circadian sleep/wake cycle, sleep
subclass of: Restriction
  on property: regulates
  some values from: circadian sleep/wake cycle, REM sleep

negative regulation of circadian sleep/wake cycle, sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: circadian sleep/wake cycle, sleep
subclass of: negative regulation of circadian rhythm
subclass of: regulation of circadian sleep/wake cycle, sleep
subclass of: negative regulation of behavior
subclass of: Restriction
  on property: negatively regulates
  some values from: circadian sleep/wake cycle, sleep

negative regulation of circadian sleep/wake cycle, REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: circadian sleep/wake cycle, REM sleep
subclass of: regulation of circadian sleep/wake cycle, REM sleep
subclass of: negative regulation of circadian sleep/wake cycle, sleep
subclass of: Restriction
  on property: negatively regulates
  some values from: circadian sleep/wake cycle, REM sleep

negative regulation of circadian sleep/wake cycle, non-REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: circadian sleep/wake cycle, non-REM sleep
subclass of: negative regulation of circadian sleep/wake cycle, sleep
subclass of: regulation of circadian sleep/wake cycle, non-REM sleep
subclass of: Restriction
  on property: negatively regulates
  some values from: circadian sleep/wake cycle, non-REM sleep

regulation of phosphorylation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: phosphorylation
subclass of: regulation of phosphate metabolic process
subclass of: Restriction
  on property: regulates
  some values from: phosphorylation

negative regulation of phosphorylation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: phosphorylation
subclass of: regulation of phosphorylation
subclass of: negative regulation of phosphate metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: phosphorylation

positive regulation of phosphorylation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: phosphorylation
subclass of: regulation of phosphorylation
subclass of: positive regulation of phosphate metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: phosphorylation

homeostatic process
type: Class
subclass of: biological_process

circadian sleep/wake cycle
type: Class
subclass of: circadian behavior

circadian sleep/wake cycle, REM sleep
type: Class
subclass of: circadian sleep/wake cycle process
subclass of: Restriction
  on property: part of
  some values from: circadian sleep/wake cycle, sleep

circadian sleep/wake cycle, non-REM sleep
type: Class
subclass of: circadian sleep/wake cycle process
subclass of: Restriction
  on property: part of
  some values from: circadian sleep/wake cycle, sleep

regulation of circadian sleep/wake cycle
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: circadian sleep/wake cycle
subclass of: regulation of circadian rhythm
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: circadian sleep/wake cycle

regulation of circadian rhythm
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: circadian rhythm
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: circadian rhythm

positive regulation of circadian rhythm
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: circadian rhythm
subclass of: regulation of circadian rhythm
subclass of: positive regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: circadian rhythm

negative regulation of circadian rhythm
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: circadian rhythm
subclass of: regulation of circadian rhythm
subclass of: negative regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: circadian rhythm

eating behavior
type: Class
subclass of: feeding behavior

drinking behavior
type: Class
subclass of: feeding behavior

amide transport
type: Class
subclass of: nitrogen compound transport

cell projection
type: Class
subclass of: cellular anatomical entity

neuron projection
type: Class
subclass of: plasma membrane bounded cell projection
RO_0002161: NCBITaxon 4751

chordate embryonic development
type: Class
subclass of: embryo development ending in birth or egg hatching

neuronal cell body
type: Class
subclass of: cell body
subclass of: Restriction
  on property: part of
  some values from: somatodendritic compartment
comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.

positive regulation of catalytic activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: catalytic activity
subclass of: positive regulation of molecular function
subclass of: regulation of catalytic activity
subclass of: Restriction
  on property: positively regulates
  some values from: catalytic activity

negative regulation of catalytic activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: catalytic activity
subclass of: negative regulation of molecular function
subclass of: regulation of catalytic activity
subclass of: Restriction
  on property: negatively regulates
  some values from: catalytic activity

macromolecule metabolic process
type: Class
subclass of: organic substance metabolic process

organelle
type: Class
subclass of: cellular anatomical entity

membrane-bounded organelle
type: Class
equivalent class: Class
  intersection of: organelle
  intersection of: Restriction
    on property: has part
    some values from: membrane
subclass of: organelle
subclass of: Restriction
  on property: has part
  some values from: membrane

non-membrane-bounded organelle
type: Class
subclass of: organelle
IAO_0000233: https://github.com/geneontology/go-ontology/issues/21881

intracellular organelle
type: Class
equivalent class: Class
  intersection of: organelle
  intersection of: Restriction
    on property: part of
    some values from: intracellular anatomical structure
subclass of: organelle
subclass of: Restriction
  on property: part of
  some values from: intracellular anatomical structure

extracellular organelle
type: Class
equivalent class: Class
  intersection of: organelle
  intersection of: Restriction
    on property: part of
    some values from: extracellular region
subclass of: organelle
subclass of: Restriction
  on property: part of
  some values from: extracellular region

intracellular membrane-bounded organelle
type: Class
equivalent class: Class
  intersection of: membrane-bounded organelle
  intersection of: Restriction
    on property: part of
    some values from: intracellular anatomical structure
subclass of: membrane-bounded organelle
subclass of: intracellular organelle

intracellular non-membrane-bounded organelle
type: Class
equivalent class: Class
  intersection of: non-membrane-bounded organelle
  intersection of: Restriction
    on property: part of
    some values from: intracellular anatomical structure
subclass of: non-membrane-bounded organelle
subclass of: intracellular organelle

regulation of carbohydrate biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: carbohydrate biosynthetic process
subclass of: regulation of carbohydrate metabolic process
subclass of: regulation of biosynthetic process
subclass of: Restriction
  on property: regulates
  some values from: carbohydrate biosynthetic process

extracellular non-membrane-bounded organelle
type: Class
equivalent class: Class
  intersection of: non-membrane-bounded organelle
  intersection of: Restriction
    on property: part of
    some values from: extracellular region
subclass of: non-membrane-bounded organelle
subclass of: extracellular organelle

regulation of monoatomic ion transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: monoatomic ion transport
subclass of: regulation of transport
subclass of: Restriction
  on property: regulates
  some values from: monoatomic ion transport

positive regulation of monoatomic ion transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: monoatomic ion transport
subclass of: regulation of monoatomic ion transport
subclass of: positive regulation of transport
subclass of: Restriction
  on property: positively regulates
  some values from: monoatomic ion transport

negative regulation of monoatomic ion transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: monoatomic ion transport
subclass of: regulation of monoatomic ion transport
subclass of: negative regulation of transport
subclass of: Restriction
  on property: negatively regulates
  some values from: monoatomic ion transport

oxoacid metabolic process
type: Class
subclass of: organic acid metabolic process

regulation of generation of precursor metabolites and energy
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: generation of precursor metabolites and energy
subclass of: regulation of cellular metabolic process
subclass of: Restriction
  on property: regulates
  some values from: generation of precursor metabolites and energy

regulation of carbohydrate catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: carbohydrate catabolic process
subclass of: regulation of carbohydrate metabolic process
subclass of: regulation of catabolic process
subclass of: Restriction
  on property: regulates
  some values from: carbohydrate catabolic process

regulation of kinase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: kinase activity
subclass of: regulation of phosphorylation
subclass of: regulation of transferase activity
subclass of: Restriction
  on property: regulates
  some values from: kinase activity

regulation of respiratory gaseous exchange
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: respiratory gaseous exchange by respiratory system
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: respiratory gaseous exchange by respiratory system

glucan metabolic process
type: Class
subclass of: polysaccharide metabolic process

regulation of system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: system process
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: system process

regulation of digestive system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: digestive system process
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: digestive system process

regulation of endocrine process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: endocrine process
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: endocrine process

regulation of excretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: excretion
subclass of: regulation of system process
subclass of: regulation of secretion
subclass of: Restriction
  on property: regulates
  some values from: excretion

regulation of respiratory system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: respiratory system process
subclass of: regulation of respiratory gaseous exchange
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: respiratory system process

negative regulation of molecular function
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: molecular_function
subclass of: regulation of molecular function
subclass of: Restriction
  on property: negatively regulates
  some values from: molecular_function

positive regulation of molecular function
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: molecular_function
subclass of: regulation of molecular function
subclass of: Restriction
  on property: positively regulates
  some values from: molecular_function

cellular metabolic process
type: Class
subclass of: metabolic process
subclass of: cellular process
comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.

primary metabolic process
type: Class
subclass of: metabolic process

cellular catabolic process
type: Class
subclass of: catabolic process
subclass of: cellular metabolic process

cellular biosynthetic process
type: Class
subclass of: biosynthetic process
subclass of: cellular metabolic process

small molecule metabolic process
type: Class
subclass of: metabolic process
comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.

small molecule biosynthetic process
type: Class
subclass of: biosynthetic process
subclass of: small molecule metabolic process
comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.

cell body
type: Class
subclass of: cellular anatomical entity
RO_0002161: NCBITaxon 4890
comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.

establishment of protein localization
type: Class
subclass of: protein localization
subclass of: establishment of localization

regulation of circadian sleep/wake cycle, sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: circadian sleep/wake cycle, sleep
subclass of: regulation of circadian sleep/wake cycle
subclass of: Restriction
  on property: regulates
  some values from: circadian sleep/wake cycle, sleep

regulation of circadian sleep/wake cycle, non-REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: circadian sleep/wake cycle, non-REM sleep
subclass of: regulation of circadian sleep/wake cycle, sleep
subclass of: Restriction
  on property: regulates
  some values from: circadian sleep/wake cycle, non-REM sleep

obsolete post-mating behavior
type: Class
comment: This term was obsoleted because it was not precisely defined.
deprecated: true

negative regulation of glycogen biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: glycogen biosynthetic process
subclass of: regulation of glycogen biosynthetic process
subclass of: negative regulation of macromolecule biosynthetic process
subclass of: negative regulation of glycogen metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: glycogen biosynthetic process

positive regulation of glycogen biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: glycogen biosynthetic process
subclass of: regulation of glycogen biosynthetic process
subclass of: positive regulation of macromolecule biosynthetic process
subclass of: positive regulation of cellular biosynthetic process
subclass of: positive regulation of glycogen metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: glycogen biosynthetic process

positive regulation of ossification
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: ossification
subclass of: regulation of ossification
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: ossification

negative regulation of glycogen catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: glycogen catabolic process
subclass of: regulation of glycogen catabolic process
subclass of: negative regulation of cellular catabolic process
subclass of: negative regulation of glycogen metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: glycogen catabolic process

positive regulation of glycogen catabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: glycogen catabolic process
subclass of: regulation of glycogen catabolic process
subclass of: positive regulation of cellular catabolic process
subclass of: positive regulation of glycogen metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: glycogen catabolic process

negative regulation of heart contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: heart contraction
subclass of: regulation of heart contraction
subclass of: negative regulation of blood circulation
subclass of: Restriction
  on property: negatively regulates
  some values from: heart contraction

positive regulation of heart contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: heart contraction
subclass of: regulation of heart contraction
subclass of: positive regulation of blood circulation
subclass of: Restriction
  on property: positively regulates
  some values from: heart contraction

negative regulation of lipid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: lipid metabolic process
subclass of: negative regulation of metabolic process
subclass of: regulation of lipid metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: lipid metabolic process

positive regulation of lipid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: lipid metabolic process
subclass of: positive regulation of metabolic process
subclass of: regulation of lipid metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: lipid metabolic process

negative regulation of carbohydrate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: carbohydrate metabolic process
subclass of: regulation of carbohydrate metabolic process
subclass of: negative regulation of metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: carbohydrate metabolic process

positive regulation of carbohydrate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: carbohydrate metabolic process
subclass of: regulation of carbohydrate metabolic process
subclass of: positive regulation of metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: carbohydrate metabolic process

negative regulation of muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: muscle contraction
subclass of: regulation of muscle contraction
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: muscle contraction

positive regulation of muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: muscle contraction
subclass of: regulation of muscle contraction
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: muscle contraction

negative regulation of phosphate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: phosphate-containing compound metabolic process
subclass of: negative regulation of phosphorus metabolic process
subclass of: regulation of phosphate metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: phosphate-containing compound metabolic process

positive regulation of phosphate metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: phosphate-containing compound metabolic process
subclass of: positive regulation of phosphorus metabolic process
subclass of: regulation of phosphate metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: phosphate-containing compound metabolic process

positive regulation of circadian sleep/wake cycle, sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: circadian sleep/wake cycle, sleep
subclass of: positive regulation of circadian rhythm
subclass of: regulation of circadian sleep/wake cycle, sleep
subclass of: positive regulation of behavior
subclass of: Restriction
  on property: positively regulates
  some values from: circadian sleep/wake cycle, sleep

negative regulation of steroid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: steroid metabolic process
subclass of: regulation of steroid metabolic process
subclass of: negative regulation of lipid metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: steroid metabolic process

positive regulation of steroid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: steroid metabolic process
subclass of: regulation of steroid metabolic process
subclass of: positive regulation of lipid metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: steroid metabolic process

negative regulation of smooth muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: smooth muscle contraction
subclass of: regulation of smooth muscle contraction
subclass of: negative regulation of muscle contraction
subclass of: Restriction
  on property: negatively regulates
  some values from: smooth muscle contraction

positive regulation of smooth muscle contraction
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: smooth muscle contraction
subclass of: regulation of smooth muscle contraction
subclass of: positive regulation of muscle contraction
subclass of: Restriction
  on property: positively regulates
  some values from: smooth muscle contraction

negative regulation of embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: embryo development
subclass of: regulation of embryonic development
subclass of: negative regulation of developmental process
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: embryo development

regulation of embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: embryo development
subclass of: regulation of multicellular organismal development
subclass of: Restriction
  on property: regulates
  some values from: embryo development

positive regulation of circadian sleep/wake cycle, REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: circadian sleep/wake cycle, REM sleep
subclass of: regulation of circadian sleep/wake cycle, REM sleep
subclass of: positive regulation of circadian sleep/wake cycle, sleep
subclass of: Restriction
  on property: positively regulates
  some values from: circadian sleep/wake cycle, REM sleep

positive regulation of circadian sleep/wake cycle, non-REM sleep
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: circadian sleep/wake cycle, non-REM sleep
subclass of: regulation of circadian sleep/wake cycle, non-REM sleep
subclass of: positive regulation of circadian sleep/wake cycle, sleep
subclass of: Restriction
  on property: positively regulates
  some values from: circadian sleep/wake cycle, non-REM sleep

carboxylic acid biosynthetic process
type: Class
subclass of: organic acid biosynthetic process
subclass of: carboxylic acid metabolic process

negative regulation of insulin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: insulin secretion
subclass of: negative regulation of protein secretion
subclass of: regulation of insulin secretion
subclass of: negative regulation of peptide hormone secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: insulin secretion

acid secretion
type: Class
subclass of: secretion

hormone secretion
type: Class
subclass of: hormone transport
subclass of: signal release

regulation of hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: hormone secretion
subclass of: regulation of cell communication
subclass of: regulation of hormone levels
subclass of: regulation of signaling
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: regulates
  some values from: hormone secretion

positive regulation of hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: hormone secretion
subclass of: positive regulation of cell communication
subclass of: positive regulation of signaling
subclass of: regulation of hormone secretion
subclass of: positive regulation of secretion by cell
subclass of: Restriction
  on property: positively regulates
  some values from: hormone secretion

negative regulation of hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: hormone secretion
subclass of: negative regulation of cell communication
subclass of: negative regulation of signaling
subclass of: regulation of hormone secretion
subclass of: negative regulation of secretion by cell
subclass of: Restriction
  on property: negatively regulates
  some values from: hormone secretion

positive regulation of lipid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: lipid biosynthetic process
subclass of: positive regulation of biosynthetic process
subclass of: positive regulation of lipid metabolic process
subclass of: regulation of lipid biosynthetic process
subclass of: Restriction
  on property: positively regulates
  some values from: lipid biosynthetic process

regulation of lipid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: lipid biosynthetic process
subclass of: regulation of biosynthetic process
subclass of: regulation of lipid metabolic process
subclass of: Restriction
  on property: regulates
  some values from: lipid biosynthetic process

secretion
type: Class
subclass of: transport

intracellular transport
type: Class
equivalent class: Class
  intersection of: transport
  intersection of: Restriction
    on property: occurs in
    some values from: intracellular anatomical structure
subclass of: transport
subclass of: cellular localization
subclass of: establishment of localization in cell
subclass of: Restriction
  on property: occurs in
  some values from: intracellular anatomical structure

carboxylic acid transport
type: Class
subclass of: organic anion transport
subclass of: organic acid transport

norepinephrine secretion
type: Class
subclass of: norepinephrine transport
subclass of: signal release
subclass of: catecholamine secretion

mesoderm morphogenesis
type: Class
subclass of: tissue morphogenesis
subclass of: Restriction
  on property: part of
  some values from: mesoderm development

rhythmic process
type: Class
subclass of: biological_process

circadian behavior
type: Class
subclass of: rhythmic behavior
subclass of: circadian rhythm

animal organ development
type: Class
subclass of: anatomical structure development

positive regulation of biological process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: biological_process
subclass of: regulation of biological process
subclass of: Restriction
  on property: positively regulates
  some values from: biological_process

negative regulation of biological process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: biological_process
subclass of: regulation of biological process
subclass of: Restriction
  on property: negatively regulates
  some values from: biological_process

positive regulation of behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: behavior
subclass of: regulation of behavior
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: behavior

negative regulation of behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: behavior
subclass of: regulation of behavior
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: behavior

positive regulation of cellular process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cellular process
subclass of: positive regulation of biological process
subclass of: regulation of cellular process
subclass of: Restriction
  on property: positively regulates
  some values from: cellular process

negative regulation of cellular process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cellular process
subclass of: negative regulation of biological process
subclass of: regulation of cellular process
subclass of: Restriction
  on property: negatively regulates
  some values from: cellular process

regulation of post-embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: post-embryonic development
subclass of: regulation of multicellular organismal development
subclass of: Restriction
  on property: regulates
  some values from: post-embryonic development

negative regulation of post-embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: post-embryonic development
subclass of: regulation of post-embryonic development
subclass of: negative regulation of developmental process
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: post-embryonic development

positive regulation of post-embryonic development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: post-embryonic development
subclass of: regulation of post-embryonic development
subclass of: positive regulation of developmental process
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: post-embryonic development

regulation of response to stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: response to stimulus
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

positive regulation of response to stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: response to stimulus
subclass of: positive regulation of biological process
subclass of: regulation of response to stimulus
subclass of: Restriction
  on property: positively regulates
  some values from: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

negative regulation of response to stimulus
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: response to stimulus
subclass of: negative regulation of biological process
subclass of: regulation of response to stimulus
subclass of: Restriction
  on property: negatively regulates
  some values from: response to stimulus
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

embryonic morphogenesis
type: Class
subclass of: anatomical structure morphogenesis
subclass of: Restriction
  on property: part of
  some values from: embryo development

multicellular organismal reproductive process
type: Class
subclass of: reproductive process
subclass of: Restriction
  on property: part of
  some values from: multicellular organism reproduction

anatomical structure formation involved in morphogenesis
type: Class
subclass of: developmental process
subclass of: Restriction
  on property: part of
  some values from: anatomical structure morphogenesis
comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.

tissue morphogenesis
type: Class
subclass of: anatomical structure morphogenesis
subclass of: Restriction
  on property: part of
  some values from: tissue development

system development
type: Class
subclass of: anatomical structure development
subclass of: Restriction
  on property: part of
  some values from: multicellular organism development

branching morphogenesis of an epithelial tube
type: Class
subclass of: tube morphogenesis
subclass of: morphogenesis of a branching epithelium
subclass of: Restriction
  on property: part of
  some values from: epithelial tube morphogenesis

pigment granule
type: Class
subclass of: cytoplasmic vesicle

anatomical structure development
type: Class
subclass of: developmental process

cell motility
type: Class
subclass of: cellular process
IAO_0000233: https://github.com/geneontology/go-ontology/issues/19809

multicellular organismal-level homeostasis
type: Class
subclass of: multicellular organismal process
subclass of: homeostatic process

catecholamine secretion
type: Class
subclass of: secretion by cell
subclass of: catecholamine transport

regulation of catecholamine secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: catecholamine secretion
subclass of: regulation of amine transport
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: regulates
  some values from: catecholamine secretion

regulation of protein secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: protein secretion
subclass of: regulation of protein transport
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: regulates
  some values from: protein secretion

negative regulation of protein secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: protein secretion
subclass of: regulation of protein secretion
subclass of: negative regulation of protein transport
subclass of: negative regulation of secretion by cell
subclass of: Restriction
  on property: negatively regulates
  some values from: protein secretion

positive regulation of protein secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: protein secretion
subclass of: regulation of protein secretion
subclass of: positive regulation of protein transport
subclass of: positive regulation of secretion by cell
subclass of: Restriction
  on property: positively regulates
  some values from: protein secretion

regulation of immune response
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: immune response
subclass of: regulation of immune system process
subclass of: regulation of response to stimulus
subclass of: Restriction
  on property: regulates
  some values from: immune response

negative regulation of immune response
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: immune response
subclass of: negative regulation of immune system process
subclass of: negative regulation of response to stimulus
subclass of: regulation of immune response
subclass of: Restriction
  on property: negatively regulates
  some values from: immune response

positive regulation of immune response
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: immune response
subclass of: positive regulation of immune system process
subclass of: positive regulation of response to stimulus
subclass of: regulation of immune response
subclass of: Restriction
  on property: positively regulates
  some values from: immune response

regulation of biological process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: biological_process
subclass of: biological regulation
subclass of: Restriction
  on property: regulates
  some values from: biological_process

regulation of catalytic activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: catalytic activity
subclass of: regulation of molecular function
subclass of: Restriction
  on property: regulates
  some values from: catalytic activity

regulation of developmental process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: developmental process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: developmental process

regulation of cellular process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: cellular process

regulation of behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: behavior
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: behavior

regulation of insulin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: insulin secretion
subclass of: regulation of protein secretion
subclass of: regulation of peptide hormone secretion
subclass of: Restriction
  on property: regulates
  some values from: insulin secretion

circadian sleep/wake cycle, sleep
type: Class
equivalent class: Class
  intersection of: sleep
  intersection of: Restriction
    on property: part of
    some values from: circadian sleep/wake cycle
subclass of: circadian sleep/wake cycle process
subclass of: sleep

regulation of steroid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: steroid biosynthetic process
subclass of: regulation of steroid metabolic process
subclass of: regulation of lipid biosynthetic process
subclass of: Restriction
  on property: regulates
  some values from: steroid biosynthetic process

nervous system process
type: Class
subclass of: system process
IAO_0000233: https://github.com/geneontology/go-ontology/issues/13824

regulation of body fluid levels
type: Class
subclass of: regulation of biological quality

multicellular organismal movement
type: Class
subclass of: multicellular organismal process

musculoskeletal movement
type: Class
subclass of: multicellular organismal movement
subclass of: neuromuscular process

voluntary musculoskeletal movement
type: Class
subclass of: musculoskeletal movement

neuromuscular process controlling balance
type: Class
subclass of: neuromuscular process
subclass of: Restriction
  on property: has part
  some values from: musculoskeletal movement

endocrine process
type: Class
subclass of: system process

cognition
type: Class
subclass of: nervous system process

response to stimulus
type: Class
subclass of: biological_process
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

neuromuscular process
type: Class
subclass of: nervous system process

detection of stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of stimulus
subclass of: Restriction
  on property: part of
  some values from: sensory perception

detection of chemical stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of chemical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of chemical stimulus
subclass of: detection of stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of chemical stimulus

detection of light stimulus involved in visual perception
type: Class
equivalent class: Class
  intersection of: detection of light stimulus
  intersection of: Restriction
    on property: part of
    some values from: visual perception
subclass of: detection of visible light
subclass of: detection of light stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: visual perception

sensory perception of taste
type: Class
subclass of: sensory perception of chemical stimulus

detection of mechanical stimulus involved in sensory perception of sound
type: Class
equivalent class: Class
  intersection of: detection of mechanical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of sound
subclass of: nervous system process
subclass of: detection of mechanical stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of sound

detection of chemical stimulus involved in sensory perception of smell
type: Class
equivalent class: Class
  intersection of: detection of chemical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of smell
subclass of: detection of chemical stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of smell

detection of chemical stimulus involved in sensory perception of taste
type: Class
equivalent class: Class
  intersection of: detection of chemical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of taste
subclass of: detection of chemical stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of taste

sensory perception of temperature stimulus
type: Class
subclass of: sensory perception

sensory perception of electrical stimulus
type: Class
subclass of: sensory perception

sensory perception of light stimulus
type: Class
subclass of: sensory perception

sensory perception of mechanical stimulus
type: Class
subclass of: sensory perception

thermoception
type: Class
subclass of: sensory perception of temperature stimulus

equilibrioception
type: Class
subclass of: sensory perception
subclass of: Restriction
  on property: part of
  some values from: neuromuscular process controlling balance

detection of temperature stimulus involved in thermoception
type: Class
equivalent class: Class
  intersection of: detection of temperature stimulus
  intersection of: Restriction
    on property: part of
    some values from: thermoception
subclass of: detection of temperature stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: thermoception

detection of temperature stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of temperature stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of temperature stimulus
subclass of: detection of stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of temperature stimulus

detection of light stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of light stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of light stimulus
subclass of: detection of stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of light stimulus

detection of electrical stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of electrical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of stimulus involved in sensory perception
subclass of: detection of electrical stimulus
subclass of: Restriction
  on property: part of
  some values from: sensory perception of electrical stimulus

detection of temperature stimulus involved in sensory perception of pain
type: Class
equivalent class: Class
  intersection of: detection of temperature stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of pain
subclass of: detection of temperature stimulus involved in sensory perception
subclass of: detection of stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in sensory perception of pain
type: Class
equivalent class: Class
  intersection of: detection of mechanical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of pain
subclass of: detection of mechanical stimulus involved in sensory perception
subclass of: detection of stimulus involved in sensory perception of pain

detection of electrical stimulus involved in sensory perception of pain
type: Class
equivalent class: Class
  intersection of: detection of electrical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of pain
subclass of: detection of electrical stimulus involved in sensory perception
subclass of: detection of stimulus involved in sensory perception of pain

detection of chemical stimulus involved in sensory perception of pain
type: Class
equivalent class: Class
  intersection of: detection of chemical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of pain
subclass of: detection of chemical stimulus involved in sensory perception
subclass of: detection of stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in equilibrioception
type: Class
equivalent class: Class
  intersection of: detection of mechanical stimulus
  intersection of: Restriction
    on property: part of
    some values from: equilibrioception
subclass of: detection of mechanical stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: equilibrioception

detection of mechanical stimulus involved in sensory perception
type: Class
equivalent class: Class
  intersection of: detection of mechanical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception
subclass of: detection of stimulus involved in sensory perception
subclass of: detection of mechanical stimulus
subclass of: Restriction
  on property: part of
  some values from: sensory perception of mechanical stimulus

sensory perception of touch
type: Class
subclass of: sensory perception of mechanical stimulus

detection of mechanical stimulus involved in sensory perception of touch
type: Class
equivalent class: Class
  intersection of: detection of mechanical stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of touch
subclass of: detection of mechanical stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of touch

detection of electrical stimulus
type: Class
subclass of: detection of abiotic stimulus
subclass of: response to electrical stimulus

detection of mechanical stimulus
type: Class
subclass of: detection of external stimulus
subclass of: detection of abiotic stimulus
subclass of: response to mechanical stimulus

regulation of secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: secretion
subclass of: regulation of transport
subclass of: Restriction
  on property: regulates
  some values from: secretion

positive regulation of secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: secretion
subclass of: regulation of secretion
subclass of: positive regulation of transport
subclass of: Restriction
  on property: positively regulates
  some values from: secretion

negative regulation of secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: secretion
subclass of: regulation of secretion
subclass of: negative regulation of transport
subclass of: Restriction
  on property: negatively regulates
  some values from: secretion

regulation of transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: transport
subclass of: regulation of localization
subclass of: Restriction
  on property: regulates
  some values from: transport

positive regulation of transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: transport
subclass of: positive regulation of biological process
subclass of: regulation of transport
subclass of: Restriction
  on property: positively regulates
  some values from: transport

negative regulation of transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: transport
subclass of: negative regulation of biological process
subclass of: regulation of transport
subclass of: Restriction
  on property: negatively regulates
  some values from: transport

negative regulation of lipid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: lipid biosynthetic process
subclass of: negative regulation of biosynthetic process
subclass of: negative regulation of lipid metabolic process
subclass of: regulation of lipid biosynthetic process
subclass of: Restriction
  on property: negatively regulates
  some values from: lipid biosynthetic process

negative regulation of developmental process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: developmental process
subclass of: negative regulation of biological process
subclass of: regulation of developmental process
subclass of: Restriction
  on property: negatively regulates
  some values from: developmental process

positive regulation of developmental process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: developmental process
subclass of: positive regulation of biological process
subclass of: regulation of developmental process
subclass of: Restriction
  on property: positively regulates
  some values from: developmental process

regulation of cellular component organization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular component organization
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cellular component organization

negative regulation of cellular component organization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cellular component organization
subclass of: negative regulation of cellular process
subclass of: regulation of cellular component organization
subclass of: Restriction
  on property: negatively regulates
  some values from: cellular component organization

positive regulation of cellular component organization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cellular component organization
subclass of: positive regulation of cellular process
subclass of: regulation of cellular component organization
subclass of: Restriction
  on property: positively regulates
  some values from: cellular component organization

regulation of phosphorus metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: phosphorus metabolic process
subclass of: regulation of cellular metabolic process
subclass of: Restriction
  on property: regulates
  some values from: phosphorus metabolic process

localization
type: Class
subclass of: biological_process

cartilage development
type: Class
subclass of: animal organ development
subclass of: Restriction
  on property: part of
  some values from: skeletal system development
subclass of: Restriction
  on property: part of
  some values from: connective tissue development

positive regulation of protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: protein transport
subclass of: positive regulation of transport
subclass of: regulation of protein transport
subclass of: positive regulation of establishment of protein localization
subclass of: Restriction
  on property: positively regulates
  some values from: protein transport

regulation of protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: protein transport
subclass of: regulation of transport
subclass of: regulation of establishment of protein localization
subclass of: Restriction
  on property: regulates
  some values from: protein transport

negative regulation of protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: protein transport
subclass of: negative regulation of transport
subclass of: regulation of protein transport
subclass of: negative regulation of establishment of protein localization
subclass of: Restriction
  on property: negatively regulates
  some values from: protein transport

establishment of localization
type: Class
subclass of: localization

regulation of multicellular organismal process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: multicellular organismal process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: multicellular organismal process

positive regulation of multicellular organismal process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: multicellular organismal process
subclass of: positive regulation of biological process
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: multicellular organismal process

negative regulation of multicellular organismal process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: multicellular organismal process
subclass of: negative regulation of biological process
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: multicellular organismal process

cell division
type: Class
subclass of: cellular process
comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.

regulation of cell division
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cell division
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cell division

regulation of transferase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: transferase activity
subclass of: regulation of catalytic activity
subclass of: Restriction
  on property: regulates
  some values from: transferase activity
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.

positive regulation of transferase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: transferase activity
subclass of: positive regulation of catalytic activity
subclass of: regulation of transferase activity
subclass of: Restriction
  on property: positively regulates
  some values from: transferase activity
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.

negative regulation of transferase activity
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: transferase activity
subclass of: negative regulation of catalytic activity
subclass of: regulation of transferase activity
subclass of: Restriction
  on property: negatively regulates
  some values from: transferase activity
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.

visual perception involved in equilibrioception
type: Class
equivalent class: Class
  intersection of: visual perception
  intersection of: Restriction
    on property: part of
    some values from: equilibrioception
subclass of: visual perception
subclass of: Restriction
  on property: part of
  some values from: equilibrioception

response to electrical stimulus
type: Class
subclass of: response to abiotic stimulus

detection of stimulus
type: Class
subclass of: response to stimulus

cellular localization
type: Class
subclass of: cellular process
subclass of: localization

establishment of localization in cell
type: Class
subclass of: establishment of localization
subclass of: Restriction
  on property: part of
  some values from: cellular localization

biological process involved in intraspecies interaction between organisms
type: Class
subclass of: biological_process
IAO_0000233: https://github.com/geneontology/go-ontology/issues/20191

positive regulation of cell division
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cell division
subclass of: positive regulation of cellular process
subclass of: regulation of cell division
subclass of: Restriction
  on property: positively regulates
  some values from: cell division

negative regulation of cell division
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cell division
subclass of: negative regulation of cellular process
subclass of: regulation of cell division
subclass of: Restriction
  on property: negatively regulates
  some values from: cell division

regulation of sensory perception of pain
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: sensory perception of pain
subclass of: regulation of sensory perception
subclass of: Restriction
  on property: regulates
  some values from: sensory perception of pain

regulation of sensory perception
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: sensory perception
subclass of: regulation of nervous system process
subclass of: Restriction
  on property: regulates
  some values from: sensory perception

catecholamine transport
type: Class
subclass of: monoamine transport
subclass of: organic hydroxy compound transport

regulation of amine transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: amine transport
subclass of: regulation of transport
subclass of: Restriction
  on property: regulates
  some values from: amine transport

negative regulation of amine transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: amine transport
subclass of: negative regulation of transport
subclass of: regulation of amine transport
subclass of: Restriction
  on property: negatively regulates
  some values from: amine transport

positive regulation of amine transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: amine transport
subclass of: positive regulation of transport
subclass of: regulation of amine transport
subclass of: Restriction
  on property: positively regulates
  some values from: amine transport

regulation of nervous system development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: nervous system development
subclass of: regulation of multicellular organismal development
subclass of: Restriction
  on property: regulates
  some values from: nervous system development

negative regulation of nervous system development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: nervous system development
subclass of: negative regulation of developmental process
subclass of: negative regulation of multicellular organismal process
subclass of: regulation of nervous system development
subclass of: Restriction
  on property: negatively regulates
  some values from: nervous system development

positive regulation of nervous system development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: nervous system development
subclass of: positive regulation of developmental process
subclass of: positive regulation of multicellular organismal process
subclass of: regulation of nervous system development
subclass of: Restriction
  on property: positively regulates
  some values from: nervous system development

reflex
type: Class
subclass of: response to external stimulus

vestibular reflex
type: Class
subclass of: reflex

heart contraction
type: Class
subclass of: heart process
subclass of: Restriction
  on property: part of
  some values from: blood circulation

micturition
type: Class
subclass of: renal system process
subclass of: excretion

smooth muscle contraction involved in micturition
type: Class
equivalent class: Class
  intersection of: smooth muscle contraction
  intersection of: Restriction
    on property: part of
    some values from: micturition
subclass of: urinary bladder smooth muscle contraction
subclass of: Restriction
  on property: part of
  some values from: micturition

male mating behavior
type: Class
subclass of: mating behavior

female mating behavior
type: Class
subclass of: mating behavior

regulation of macromolecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: macromolecule metabolic process
subclass of: regulation of metabolic process
subclass of: Restriction
  on property: regulates
  some values from: macromolecule metabolic process

regulation of feeding behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: feeding behavior
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: feeding behavior

crying behavior
type: Class
subclass of: behavior

regulation of cellular localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cellular localization
subclass of: regulation of localization
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cellular localization

epithelium development
type: Class
subclass of: tissue development

regulation of gastric acid secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: gastric acid secretion
subclass of: regulation of digestive system process
subclass of: regulation of secretion
subclass of: Restriction
  on property: regulates
  some values from: gastric acid secretion

positive regulation of gastric acid secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: gastric acid secretion
subclass of: positive regulation of secretion
subclass of: regulation of gastric acid secretion
subclass of: positive regulation of digestive system process
subclass of: Restriction
  on property: positively regulates
  some values from: gastric acid secretion

negative regulation of gastric acid secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: gastric acid secretion
subclass of: negative regulation of secretion
subclass of: regulation of gastric acid secretion
subclass of: negative regulation of digestive system process
subclass of: Restriction
  on property: negatively regulates
  some values from: gastric acid secretion

positive regulation of digestive system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: digestive system process
subclass of: regulation of digestive system process
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: digestive system process

negative regulation of digestive system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: digestive system process
subclass of: regulation of digestive system process
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: digestive system process

epithelial tube morphogenesis
type: Class
subclass of: morphogenesis of an epithelium
subclass of: tube morphogenesis

regulation of morphogenesis of a branching structure
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: morphogenesis of a branching structure
subclass of: regulation of anatomical structure morphogenesis
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: morphogenesis of a branching structure

hepaticobiliary system process
type: Class
subclass of: system process

membrane organization
type: Class
subclass of: cellular component organization

regulation of cartilage development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cartilage development
subclass of: regulation of multicellular organismal development
subclass of: Restriction
  on property: regulates
  some values from: cartilage development

positive regulation of cartilage development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cartilage development
subclass of: positive regulation of developmental process
subclass of: positive regulation of multicellular organismal process
subclass of: regulation of cartilage development
subclass of: Restriction
  on property: positively regulates
  some values from: cartilage development

negative regulation of cartilage development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cartilage development
subclass of: negative regulation of developmental process
subclass of: negative regulation of multicellular organismal process
subclass of: regulation of cartilage development
subclass of: Restriction
  on property: negatively regulates
  some values from: cartilage development

regulation of nematode larval development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: nematode larval development
subclass of: regulation of post-embryonic development
subclass of: Restriction
  on property: regulates
  some values from: nematode larval development

positive regulation of nematode larval development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: nematode larval development
subclass of: positive regulation of post-embryonic development
subclass of: regulation of nematode larval development
subclass of: Restriction
  on property: positively regulates
  some values from: nematode larval development

negative regulation of nematode larval development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: nematode larval development
subclass of: negative regulation of post-embryonic development
subclass of: regulation of nematode larval development
subclass of: Restriction
  on property: negatively regulates
  some values from: nematode larval development

morphogenesis of a branching epithelium
type: Class
subclass of: morphogenesis of a branching structure
subclass of: morphogenesis of an epithelium

connective tissue development
type: Class
subclass of: tissue development

regulation of small molecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: small molecule metabolic process
subclass of: regulation of metabolic process
subclass of: Restriction
  on property: regulates
  some values from: small molecule metabolic process

positive regulation of small molecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: small molecule metabolic process
subclass of: positive regulation of metabolic process
subclass of: regulation of small molecule metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: small molecule metabolic process

negative regulation of small molecule metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: small molecule metabolic process
subclass of: negative regulation of metabolic process
subclass of: regulation of small molecule metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: small molecule metabolic process

collagen-containing extracellular matrix
type: Class
subclass of: extracellular matrix

detection of stimulus involved in sensory perception of pain
type: Class
equivalent class: Class
  intersection of: detection of stimulus
  intersection of: Restriction
    on property: part of
    some values from: sensory perception of pain
subclass of: detection of stimulus involved in sensory perception
subclass of: Restriction
  on property: part of
  some values from: sensory perception of pain

biological regulation
type: Class
subclass of: biological_process

regulation of biological quality
type: Class
subclass of: biological regulation

regulation of molecular function
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: molecular_function
subclass of: biological regulation
subclass of: Restriction
  on property: regulates
  some values from: molecular_function

extracellular membrane-bounded organelle
type: Class
equivalent class: Class
  intersection of: membrane-bounded organelle
  intersection of: Restriction
    on property: part of
    some values from: extracellular region
subclass of: membrane-bounded organelle
subclass of: extracellular organelle

tear secretion
type: Class
subclass of: body fluid secretion
subclass of: secretion by tissue

glucagon secretion
type: Class
subclass of: peptide hormone secretion

regulation of glucagon secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glucagon secretion
subclass of: regulation of peptide hormone secretion
subclass of: Restriction
  on property: regulates
  some values from: glucagon secretion

negative regulation of glucagon secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: glucagon secretion
subclass of: regulation of glucagon secretion
subclass of: negative regulation of peptide hormone secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: glucagon secretion

positive regulation of glucagon secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: glucagon secretion
subclass of: regulation of glucagon secretion
subclass of: positive regulation of peptide hormone secretion
subclass of: Restriction
  on property: positively regulates
  some values from: glucagon secretion

anchoring junction
type: Class
subclass of: cell junction

regulation of establishment of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: establishment of protein localization
subclass of: regulation of protein localization
subclass of: Restriction
  on property: regulates
  some values from: establishment of protein localization

somatostatin secretion
type: Class
subclass of: peptide hormone secretion

mucus secretion
type: Class
subclass of: body fluid secretion
subclass of: secretion by tissue

regulation of mucus secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: mucus secretion
subclass of: regulation of body fluid levels
subclass of: regulation of secretion
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: mucus secretion

negative regulation of mucus secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: mucus secretion
subclass of: negative regulation of secretion
subclass of: negative regulation of multicellular organismal process
subclass of: regulation of mucus secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: mucus secretion

positive regulation of mucus secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: mucus secretion
subclass of: positive regulation of secretion
subclass of: positive regulation of multicellular organismal process
subclass of: regulation of mucus secretion
subclass of: Restriction
  on property: positively regulates
  some values from: mucus secretion

cellular macromolecule localization
type: Class
subclass of: macromolecule localization
subclass of: cellular localization

regulation of bile acid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: bile acid biosynthetic process
subclass of: regulation of cellular ketone metabolic process
subclass of: regulation of cellular biosynthetic process
subclass of: regulation of steroid biosynthetic process
subclass of: regulation of bile acid metabolic process
subclass of: Restriction
  on property: regulates
  some values from: bile acid biosynthetic process

negative regulation of bile acid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: bile acid biosynthetic process
subclass of: negative regulation of steroid biosynthetic process
subclass of: negative regulation of cellular biosynthetic process
subclass of: regulation of bile acid biosynthetic process
subclass of: negative regulation of bile acid metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: bile acid biosynthetic process

positive regulation of bile acid biosynthetic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: bile acid biosynthetic process
subclass of: positive regulation of steroid biosynthetic process
subclass of: positive regulation of cellular biosynthetic process
subclass of: regulation of bile acid biosynthetic process
subclass of: positive regulation of bile acid metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: bile acid biosynthetic process

regulation of glycogen metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: glycogen metabolic process
subclass of: regulation of polysaccharide metabolic process
subclass of: regulation of generation of precursor metabolites and energy
subclass of: Restriction
  on property: regulates
  some values from: glycogen metabolic process

negative regulation of glycogen metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: glycogen metabolic process
subclass of: negative regulation of macromolecule metabolic process
subclass of: negative regulation of cellular metabolic process
subclass of: negative regulation of carbohydrate metabolic process
subclass of: regulation of glycogen metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: glycogen metabolic process

positive regulation of glycogen metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: glycogen metabolic process
subclass of: positive regulation of macromolecule metabolic process
subclass of: positive regulation of glucose metabolic process
subclass of: positive regulation of cellular metabolic process
subclass of: regulation of glycogen metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: glycogen metabolic process

mastication
type: Class
subclass of: digestive system process

protein localization to extracellular region
type: Class
subclass of: protein localization

organic substance transport
type: Class
subclass of: transport

organic substance metabolic process
type: Class
subclass of: metabolic process

nitrogen compound transport
type: Class
subclass of: transport

cellular component organization or biogenesis
type: Class
subclass of: cellular process

cell periphery
type: Class
subclass of: cellular anatomical entity

elastic fiber
type: Class
subclass of: supramolecular fiber
subclass of: Restriction
  on property: part of
  some values from: extracellular matrix

epithelial tube formation
type: Class
subclass of: tube formation
subclass of: Restriction
  on property: part of
  some values from: epithelial tube morphogenesis
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22302

negative regulation of mesenchymal cell proliferation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: mesenchymal cell proliferation
subclass of: negative regulation of cell population proliferation
subclass of: regulation of mesenchymal cell proliferation
subclass of: Restriction
  on property: negatively regulates
  some values from: mesenchymal cell proliferation

monocarboxylic acid biosynthetic process
type: Class
subclass of: monocarboxylic acid metabolic process
subclass of: carboxylic acid biosynthetic process

regulation of primary metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: primary metabolic process
subclass of: regulation of metabolic process
subclass of: Restriction
  on property: regulates
  some values from: primary metabolic process

regulation of response to stress
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: response to stress
subclass of: regulation of response to stimulus
subclass of: Restriction
  on property: regulates
  some values from: response to stress
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

regulation of peptide transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: peptide transport
subclass of: regulation of transport
subclass of: Restriction
  on property: regulates
  some values from: peptide transport

regulation of muscle system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: muscle system process
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: muscle system process

regulation of somatostatin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: somatostatin secretion
subclass of: regulation of peptide hormone secretion
subclass of: Restriction
  on property: regulates
  some values from: somatostatin secretion

positive regulation of somatostatin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: somatostatin secretion
subclass of: regulation of somatostatin secretion
subclass of: positive regulation of peptide hormone secretion
subclass of: Restriction
  on property: positively regulates
  some values from: somatostatin secretion

negative regulation of somatostatin secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: somatostatin secretion
subclass of: regulation of somatostatin secretion
subclass of: negative regulation of peptide hormone secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: somatostatin secretion

regulation of peptide hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: peptide hormone secretion
subclass of: regulation of peptide secretion
subclass of: regulation of hormone secretion
subclass of: Restriction
  on property: regulates
  some values from: peptide hormone secretion

positive regulation of peptide hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: peptide hormone secretion
subclass of: positive regulation of peptide secretion
subclass of: positive regulation of hormone secretion
subclass of: regulation of peptide hormone secretion
subclass of: Restriction
  on property: positively regulates
  some values from: peptide hormone secretion

negative regulation of peptide hormone secretion
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: peptide hormone secretion
subclass of: negative regulation of peptide secretion
subclass of: negative regulation of hormone secretion
subclass of: regulation of peptide hormone secretion
subclass of: Restriction
  on property: negatively regulates
  some values from: peptide hormone secretion

positive regulation of intracellular protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: intracellular protein transport
subclass of: positive regulation of intracellular transport
subclass of: regulation of intracellular protein transport
subclass of: positive regulation of protein transport
subclass of: Restriction
  on property: positively regulates
  some values from: intracellular protein transport

negative regulation of intracellular protein transport
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: intracellular protein transport
subclass of: negative regulation of intracellular transport
subclass of: regulation of intracellular protein transport
subclass of: negative regulation of protein transport
subclass of: Restriction
  on property: negatively regulates
  some values from: intracellular protein transport

regulation of locomotion involved in locomotory behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: locomotion involved in locomotory behavior
subclass of: regulation of locomotion
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: locomotion involved in locomotory behavior

positive regulation of locomotion involved in locomotory behavior
type: Class
equivalent class: Class
  intersection of: regulation of biological process
  intersection of: Restriction
    on property: positively regulates
    some values from: locomotion involved in locomotory behavior
subclass of: positive regulation of locomotion
subclass of: positive regulation of behavior
subclass of: regulation of locomotion involved in locomotory behavior
subclass of: Restriction
  on property: positively regulates
  some values from: locomotion involved in locomotory behavior

negative regulation of locomotion involved in locomotory behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: locomotion involved in locomotory behavior
subclass of: negative regulation of locomotion
subclass of: negative regulation of behavior
subclass of: regulation of locomotion involved in locomotory behavior
subclass of: Restriction
  on property: negatively regulates
  some values from: locomotion involved in locomotory behavior

renal tubular secretion
type: Class
subclass of: renal system process
subclass of: excretion
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22368

intracellular vesicle
type: Class
equivalent class: Class
  intersection of: vesicle
  intersection of: Restriction
    on property: part of
    some values from: intracellular anatomical structure
subclass of: vesicle
subclass of: intracellular membrane-bounded organelle

plasma membrane region
type: Class
equivalent class: Class
  intersection of: membrane
  intersection of: Restriction
    on property: part of
    some values from: plasma membrane
subclass of: membrane
subclass of: Restriction
  on property: part of
  some values from: plasma membrane
comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.

network-forming collagen trimer
type: Class
equivalent class: Class
  intersection of: collagen trimer
  intersection of: Restriction
    on property: part of
    some values from: collagen network
subclass of: collagen trimer
subclass of: Restriction
  on property: part of
  some values from: collagen network

banded collagen fibril
type: Class
subclass of: complex of collagen trimers
subclass of: supramolecular fiber

complex of collagen trimers
type: Class
subclass of: supramolecular complex
subclass of: Restriction
  on property: part of
  some values from: collagen-containing extracellular matrix
subclass of: Restriction
  on property: has part
  some values from: collagen trimer

collagen network
type: Class
subclass of: complex of collagen trimers
subclass of: supramolecular polymer

basement membrane collagen trimer
type: Class
equivalent class: Class
  intersection of: collagen trimer
  intersection of: Restriction
    on property: part of
    some values from: basement membrane
subclass of: collagen trimer
subclass of: Restriction
  on property: part of
  some values from: basement membrane

membrane protein complex
type: Class
equivalent class: Class
  intersection of: protein-containing complex
  intersection of: Restriction
    on property: part of
    some values from: membrane
subclass of: protein-containing complex
subclass of: Restriction
  on property: part of
  some values from: membrane

plasma membrane protein complex
type: Class
equivalent class: Class
  intersection of: protein-containing complex
  intersection of: Restriction
    on property: part of
    some values from: plasma membrane
subclass of: membrane protein complex
subclass of: Restriction
  on property: part of
  some values from: plasma membrane

regulation of renal system process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: renal system process
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: renal system process

actin-based cell projection
type: Class
subclass of: plasma membrane bounded cell projection
subclass of: Restriction
  on property: has part
  some values from: actin filament

supramolecular complex
type: Class
subclass of: cellular anatomical entity

supramolecular polymer
type: Class
subclass of: supramolecular complex

supramolecular fiber
type: Class
subclass of: supramolecular polymer

polymeric cytoskeletal fiber
type: Class
subclass of: supramolecular fiber
subclass of: Restriction
  on property: part of
  some values from: cytoskeleton

cytoplasmic region
type: Class
equivalent class: Class
  intersection of: cytoplasm
  intersection of: Restriction
    on property: part of
    some values from: cytoplasm
subclass of: cytoplasm
subclass of: Restriction
  on property: part of
  some values from: cytoplasm

cell cortex region
type: Class
equivalent class: Class
  intersection of: cell cortex
  intersection of: Restriction
    on property: part of
    some values from: cell cortex
subclass of: cell cortex
subclass of: cytoplasmic region
subclass of: Restriction
  on property: part of
  some values from: cell cortex

cellular anatomical entity
type: Class
subclass of: cellular_component

plasma membrane bounded cell projection
type: Class
equivalent class: Class
  intersection of: cell projection
  intersection of: Restriction
    on property: has part
    some values from: plasma membrane region
subclass of: cell projection
subclass of: Restriction
  on property: has part
  some values from: plasma membrane region
IAO_0000233: https://github.com/geneontology/go-ontology/issues/13193

neuron projection cytoplasm
type: Class
equivalent class: Class
  intersection of: cytoplasm
  intersection of: Restriction
    on property: part of
    some values from: neuron projection
subclass of: plasma membrane bounded cell projection cytoplasm
subclass of: Restriction
  on property: part of
  some values from: neuron projection
IAO_0000233: https://github.com/geneontology/go-ontology/issues/14472

export from cell
type: Class
subclass of: transport
subclass of: cellular process

organic cyclic compound metabolic process
type: Class
subclass of: organic substance metabolic process

organic cyclic compound biosynthetic process
type: Class
subclass of: organic cyclic compound metabolic process
subclass of: organic substance biosynthetic process

organic substance catabolic process
type: Class
subclass of: catabolic process
subclass of: organic substance metabolic process

organic substance biosynthetic process
type: Class
subclass of: biosynthetic process
subclass of: organic substance metabolic process

organic hydroxy compound metabolic process
type: Class
subclass of: organic substance metabolic process

organic hydroxy compound biosynthetic process
type: Class
subclass of: organic substance biosynthetic process
subclass of: organic hydroxy compound metabolic process

response to oxygen-containing compound
type: Class
subclass of: response to chemical

response to salt
type: Class
subclass of: response to chemical

regulation of male mating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: male mating behavior
subclass of: regulation of behavior
subclass of: regulation of reproductive process
subclass of: Restriction
  on property: regulates
  some values from: male mating behavior

negative regulation of male mating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: male mating behavior
subclass of: negative regulation of behavior
subclass of: regulation of male mating behavior
subclass of: negative regulation of reproductive process
subclass of: Restriction
  on property: negatively regulates
  some values from: male mating behavior

positive regulation of male mating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: male mating behavior
subclass of: positive regulation of behavior
subclass of: regulation of male mating behavior
subclass of: positive regulation of reproductive process
subclass of: Restriction
  on property: positively regulates
  some values from: male mating behavior

positive regulation of response to water deprivation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: response to water deprivation
subclass of: positive regulation of response to stimulus
subclass of: regulation of response to water deprivation
subclass of: Restriction
  on property: positively regulates
  some values from: response to water deprivation

regulation of blood circulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: blood circulation
subclass of: regulation of system process
subclass of: Restriction
  on property: regulates
  some values from: blood circulation

negative regulation of blood circulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: blood circulation
subclass of: negative regulation of multicellular organismal process
subclass of: regulation of blood circulation
subclass of: Restriction
  on property: negatively regulates
  some values from: blood circulation

positive regulation of blood circulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: blood circulation
subclass of: positive regulation of multicellular organismal process
subclass of: regulation of blood circulation
subclass of: Restriction
  on property: positively regulates
  some values from: blood circulation

regulation of secretion by cell
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: secretion by cell
subclass of: regulation of cellular process
subclass of: regulation of secretion
subclass of: Restriction
  on property: regulates
  some values from: secretion by cell

negative regulation of secretion by cell
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: secretion by cell
subclass of: negative regulation of cellular process
subclass of: negative regulation of secretion
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: negatively regulates
  some values from: secretion by cell

positive regulation of secretion by cell
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: secretion by cell
subclass of: positive regulation of cellular process
subclass of: positive regulation of secretion
subclass of: regulation of secretion by cell
subclass of: Restriction
  on property: positively regulates
  some values from: secretion by cell

extracellular vesicle
type: Class
equivalent class: Class
  intersection of: vesicle
  intersection of: Restriction
    on property: part of
    some values from: extracellular region
subclass of: vesicle
subclass of: extracellular membrane-bounded organelle

negative regulation of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: protein localization
subclass of: regulation of protein localization
subclass of: negative regulation of cellular process
subclass of: Restriction
  on property: negatively regulates
  some values from: protein localization
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22021

positive regulation of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: protein localization
subclass of: regulation of protein localization
subclass of: positive regulation of cellular process
subclass of: Restriction
  on property: positively regulates
  some values from: protein localization
IAO_0000233: https://github.com/geneontology/go-ontology/issues/22021

negative regulation of respiratory gaseous exchange
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: respiratory gaseous exchange by respiratory system
subclass of: regulation of respiratory gaseous exchange
subclass of: negative regulation of multicellular organismal process
subclass of: Restriction
  on property: negatively regulates
  some values from: respiratory gaseous exchange by respiratory system

positive regulation of respiratory gaseous exchange
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: respiratory gaseous exchange by respiratory system
subclass of: regulation of respiratory gaseous exchange
subclass of: positive regulation of multicellular organismal process
subclass of: Restriction
  on property: positively regulates
  some values from: respiratory gaseous exchange by respiratory system

regulation of eating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: eating behavior
subclass of: regulation of feeding behavior
subclass of: Restriction
  on property: regulates
  some values from: eating behavior

negative regulation of eating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: eating behavior
subclass of: regulation of eating behavior
subclass of: negative regulation of feeding behavior
subclass of: Restriction
  on property: negatively regulates
  some values from: eating behavior

positive regulation of eating behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: eating behavior
subclass of: regulation of eating behavior
subclass of: positive regulation of feeding behavior
subclass of: Restriction
  on property: positively regulates
  some values from: eating behavior

negative regulation of sensory perception of pain
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: sensory perception of pain
subclass of: negative regulation of nervous system process
subclass of: regulation of sensory perception of pain
subclass of: Restriction
  on property: negatively regulates
  some values from: sensory perception of pain

positive regulation of sensory perception of pain
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: sensory perception of pain
subclass of: positive regulation of nervous system process
subclass of: regulation of sensory perception of pain
subclass of: Restriction
  on property: positively regulates
  some values from: sensory perception of pain

regulation of bile acid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: bile acid metabolic process
subclass of: regulation of steroid metabolic process
subclass of: regulation of cellular metabolic process
subclass of: regulation of small molecule metabolic process
subclass of: Restriction
  on property: regulates
  some values from: bile acid metabolic process

negative regulation of bile acid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: bile acid metabolic process
subclass of: negative regulation of cellular metabolic process
subclass of: negative regulation of steroid metabolic process
subclass of: negative regulation of small molecule metabolic process
subclass of: regulation of bile acid metabolic process
subclass of: Restriction
  on property: negatively regulates
  some values from: bile acid metabolic process

positive regulation of bile acid metabolic process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: bile acid metabolic process
subclass of: positive regulation of cellular metabolic process
subclass of: positive regulation of steroid metabolic process
subclass of: positive regulation of small molecule metabolic process
subclass of: regulation of bile acid metabolic process
subclass of: Restriction
  on property: positively regulates
  some values from: bile acid metabolic process

regulation of smooth muscle contraction involved in micturition
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: smooth muscle contraction involved in micturition
subclass of: regulation of smooth muscle contraction
subclass of: regulation of excretion
subclass of: regulation of renal system process
subclass of: Restriction
  on property: regulates
  some values from: smooth muscle contraction involved in micturition

negative regulation of smooth muscle contraction involved in micturition
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: smooth muscle contraction involved in micturition
subclass of: negative regulation of smooth muscle contraction
subclass of: regulation of smooth muscle contraction involved in micturition
subclass of: Restriction
  on property: negatively regulates
  some values from: smooth muscle contraction involved in micturition

positive regulation of smooth muscle contraction involved in micturition
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: smooth muscle contraction involved in micturition
subclass of: positive regulation of smooth muscle contraction
subclass of: regulation of smooth muscle contraction involved in micturition
subclass of: Restriction
  on property: positively regulates
  some values from: smooth muscle contraction involved in micturition

negative regulation of establishment of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: establishment of protein localization
subclass of: regulation of establishment of protein localization
subclass of: negative regulation of protein localization
subclass of: Restriction
  on property: negatively regulates
  some values from: establishment of protein localization

positive regulation of establishment of protein localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: establishment of protein localization
subclass of: regulation of establishment of protein localization
subclass of: positive regulation of protein localization
subclass of: Restriction
  on property: positively regulates
  some values from: establishment of protein localization

regulation of epithelial tube formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: epithelial tube formation
subclass of: regulation of morphogenesis of an epithelium
subclass of: regulation of multicellular organismal development
subclass of: Restriction
  on property: regulates
  some values from: epithelial tube formation
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

negative regulation of epithelial tube formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: epithelial tube formation
subclass of: negative regulation of multicellular organismal process
subclass of: regulation of epithelial tube formation
subclass of: negative regulation of morphogenesis of an epithelium
subclass of: Restriction
  on property: negatively regulates
  some values from: epithelial tube formation
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

positive regulation of epithelial tube formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: epithelial tube formation
subclass of: positive regulation of multicellular organismal process
subclass of: regulation of epithelial tube formation
subclass of: positive regulation of morphogenesis of an epithelium
subclass of: Restriction
  on property: positively regulates
  some values from: epithelial tube formation
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

regulation of morphogenesis of an epithelium
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: morphogenesis of an epithelium
subclass of: regulation of anatomical structure morphogenesis
subclass of: Restriction
  on property: regulates
  some values from: morphogenesis of an epithelium
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

negative regulation of morphogenesis of an epithelium
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: morphogenesis of an epithelium
subclass of: negative regulation of developmental process
subclass of: regulation of morphogenesis of an epithelium
subclass of: Restriction
  on property: negatively regulates
  some values from: morphogenesis of an epithelium
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

positive regulation of morphogenesis of an epithelium
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: morphogenesis of an epithelium
subclass of: positive regulation of developmental process
subclass of: regulation of morphogenesis of an epithelium
subclass of: Restriction
  on property: positively regulates
  some values from: morphogenesis of an epithelium
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).

regulation of detection of mechanical stimulus involved in sensory perception of touch
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: detection of mechanical stimulus involved in sensory perception of touch
subclass of: regulation of response to external stimulus
subclass of: regulation of sensory perception
subclass of: Restriction
  on property: regulates
  some values from: detection of mechanical stimulus involved in sensory perception of touch

negative regulation of detection of mechanical stimulus involved in sensory perception of touch
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: detection of mechanical stimulus involved in sensory perception of touch
subclass of: negative regulation of nervous system process
subclass of: negative regulation of response to external stimulus
subclass of: regulation of detection of mechanical stimulus involved in sensory perception of touch
subclass of: Restriction
  on property: negatively regulates
  some values from: detection of mechanical stimulus involved in sensory perception of touch

positive regulation of detection of mechanical stimulus involved in sensory perception of touch
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: detection of mechanical stimulus involved in sensory perception of touch
subclass of: positive regulation of nervous system process
subclass of: positive regulation of response to external stimulus
subclass of: regulation of detection of mechanical stimulus involved in sensory perception of touch
subclass of: Restriction
  on property: positively regulates
  some values from: detection of mechanical stimulus involved in sensory perception of touch

regulation of mechanosensory behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: mechanosensory behavior
subclass of: regulation of response to external stimulus
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: mechanosensory behavior

negative regulation of mechanosensory behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: mechanosensory behavior
subclass of: negative regulation of response to external stimulus
subclass of: negative regulation of behavior
subclass of: regulation of mechanosensory behavior
subclass of: Restriction
  on property: negatively regulates
  some values from: mechanosensory behavior

positive regulation of mechanosensory behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: mechanosensory behavior
subclass of: positive regulation of response to external stimulus
subclass of: positive regulation of behavior
subclass of: regulation of mechanosensory behavior
subclass of: Restriction
  on property: positively regulates
  some values from: mechanosensory behavior

regulation of mesoderm formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: mesoderm formation
subclass of: regulation of developmental process
subclass of: Restriction
  on property: regulates
  some values from: mesoderm formation

negative regulation of mesoderm formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: mesoderm formation
subclass of: regulation of mesoderm formation
subclass of: negative regulation of mesoderm development
subclass of: Restriction
  on property: negatively regulates
  some values from: mesoderm formation

positive regulation of mesoderm formation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: mesoderm formation
subclass of: regulation of mesoderm formation
subclass of: positive regulation of mesoderm development
subclass of: Restriction
  on property: positively regulates
  some values from: mesoderm formation

regulation of lipid localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: lipid localization
subclass of: regulation of localization
subclass of: Restriction
  on property: regulates
  some values from: lipid localization

negative regulation of lipid localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: lipid localization
subclass of: negative regulation of biological process
subclass of: regulation of lipid localization
subclass of: Restriction
  on property: negatively regulates
  some values from: lipid localization

positive regulation of lipid localization
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: lipid localization
subclass of: positive regulation of biological process
subclass of: regulation of lipid localization
subclass of: Restriction
  on property: positively regulates
  some values from: lipid localization

regulation of multicellular organismal development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: multicellular organism development
subclass of: regulation of developmental process
subclass of: regulation of multicellular organismal process
subclass of: Restriction
  on property: regulates
  some values from: multicellular organism development

regulation of response to water deprivation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: response to water deprivation
subclass of: regulation of response to stress
subclass of: Restriction
  on property: regulates
  some values from: response to water deprivation

regulation of cell motility
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: cell motility
subclass of: regulation of locomotion
subclass of: regulation of cellular process
subclass of: Restriction
  on property: regulates
  some values from: cell motility

negative regulation of cell motility
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: cell motility
subclass of: negative regulation of locomotion
subclass of: negative regulation of cellular process
subclass of: regulation of cell motility
subclass of: Restriction
  on property: negatively regulates
  some values from: cell motility

positive regulation of cell motility
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: cell motility
subclass of: positive regulation of locomotion
subclass of: positive regulation of cellular process
subclass of: regulation of cell motility
subclass of: Restriction
  on property: positively regulates
  some values from: cell motility

regulation of reproductive process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: reproductive process
subclass of: regulation of biological process
subclass of: Restriction
  on property: regulates
  some values from: reproductive process

negative regulation of reproductive process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: reproductive process
subclass of: negative regulation of biological process
subclass of: regulation of reproductive process
subclass of: Restriction
  on property: negatively regulates
  some values from: reproductive process

positive regulation of reproductive process
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: reproductive process
subclass of: positive regulation of biological process
subclass of: regulation of reproductive process
subclass of: Restriction
  on property: positively regulates
  some values from: reproductive process

negative regulation of feeding behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: feeding behavior
subclass of: negative regulation of behavior
subclass of: regulation of feeding behavior
subclass of: Restriction
  on property: negatively regulates
  some values from: feeding behavior

positive regulation of feeding behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: feeding behavior
subclass of: positive regulation of behavior
subclass of: regulation of feeding behavior
subclass of: Restriction
  on property: positively regulates
  some values from: feeding behavior

regulation of defecation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: defecation
subclass of: regulation of digestive system process
subclass of: regulation of excretion
subclass of: Restriction
  on property: regulates
  some values from: defecation

negative regulation of defecation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: defecation
subclass of: negative regulation of secretion
subclass of: negative regulation of digestive system process
subclass of: regulation of defecation
subclass of: Restriction
  on property: negatively regulates
  some values from: defecation

positive regulation of defecation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: defecation
subclass of: positive regulation of secretion
subclass of: positive regulation of digestive system process
subclass of: regulation of defecation
subclass of: Restriction
  on property: positively regulates
  some values from: defecation

regulation of mesoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: mesoderm development
subclass of: regulation of developmental process
subclass of: Restriction
  on property: regulates
  some values from: mesoderm development

negative regulation of mesoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: mesoderm development
subclass of: negative regulation of developmental process
subclass of: regulation of mesoderm development
subclass of: Restriction
  on property: negatively regulates
  some values from: mesoderm development

positive regulation of mesoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: mesoderm development
subclass of: positive regulation of developmental process
subclass of: regulation of mesoderm development
subclass of: Restriction
  on property: positively regulates
  some values from: mesoderm development

regulation of ectoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: ectoderm development
subclass of: regulation of developmental process
subclass of: Restriction
  on property: regulates
  some values from: ectoderm development

negative regulation of ectoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: ectoderm development
subclass of: negative regulation of developmental process
subclass of: regulation of ectoderm development
subclass of: Restriction
  on property: negatively regulates
  some values from: ectoderm development

positive regulation of ectoderm development
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: ectoderm development
subclass of: positive regulation of developmental process
subclass of: regulation of ectoderm development
subclass of: Restriction
  on property: positively regulates
  some values from: ectoderm development

negative regulation of gastrulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: negatively regulates
    some values from: gastrulation
subclass of: regulation of gastrulation
subclass of: negative regulation of embryonic development
subclass of: Restriction
  on property: negatively regulates
  some values from: gastrulation

positive regulation of gastrulation
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: positively regulates
    some values from: gastrulation
subclass of: regulation of gastrulation
subclass of: positive regulation of embryonic development
subclass of: Restriction
  on property: positively regulates
  some values from: gastrulation

regulation of grooming behavior
type: Class
equivalent class: Class
  intersection of: biological regulation
  intersection of: Restriction
    on property: regulates
    some values from: grooming behavior
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: grooming behavior

body part movement
type: Class
subclass of: kinesthetic behavior
definition: A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: stationary movement
has OBO namespace: behavior_ontology

whole body movement
type: Class
subclass of: kinesthetic behavior
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

emotional behavior
type: Class
subclass of: behavior process
definition: Behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: affective behaviour
has exact synonym: mood
has OBO namespace: behavior_ontology

Axiom
annotated source: emotional behavior
annotated property: definition
annotated target: Behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences.
source: wikipedia:Emotions

reflexive behavior phenotype
type: Class
subclass of: involuntary movement behavior phenotype
definition: Observable characteristic of behaviour related to involuntary movement in response to a stimulus.
date: 2011-04-14T11:57:02Z
created by: George Gkoutos
has exact synonym: pathological reflexive behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: reflexive behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to involuntary movement in response to a stimulus.
source: NBO:GVG

learning and/or memory behavior
type: Class
subclass of: cognitive behavior
definition: Behavior related to the acquisition and processing of information and/or the storage and retrieval of this information over time.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: learning and/or memory behaviour
has OBO namespace: behavior_ontology
xref: GO:0007611

Axiom
annotated source: learning and/or memory behavior
annotated property: definition
annotated target: Behavior related to the acquisition and processing of information and/or the storage and retrieval of this information over time.
source: GO:jic

mouth movement
type: Class
subclass of: body part movement
definition: The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has narrow synonym: mouth part movement
has narrow synonym: other moved mouth parts
has OBO namespace: behavior_ontology

rhythmic behavior
type: Class
subclass of: behavior process
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007622

locomotory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: locomotory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: voluntary movement behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: locomotory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior associated with the specific movement from place to place of an organism.
date: 2011-04-14T12:58:40Z
created by: George Gkoutos
has exact synonym: pathological locomotory behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: locomotory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior associated with the specific movement from place to place of an organism.
source: NBO:GVG

reproductive behavior
type: Class
subclass of: behavior process
definition: Behavior directly related to the production of offspring [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: reproduction
has exact synonym: reproductive behaviour
has OBO namespace: behavior_ontology
xref: GO:0019098

social behavior
type: Class
subclass of: behavior process
definition: "A behavior that occurs predominantly or only, in individuals that are part of a group." [Wikipedia:Social_behavior]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: social behaviour
has OBO namespace: behavior_ontology
xref: GO:0035176

seizures/epilepsy
type: Class
subclass of: behavioral phenotype
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0001250
xref: MP:0002064

locomotory behavior
type: Class
subclass of: locomotion
subclass of: whole body movement
definition: Movement from place to place of an organism." [GO:0007626]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: locomotion
has OBO namespace: behavior_ontology
xref: GO:0007626
xref: GO:0008344

mating behavior
type: Class
subclass of: reproductive behavior
definition: Behavior related to the interactions between organisms for the purpose of mating.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: mating behaviour
has OBO namespace: behavior_ontology
xref: GO:0007617

Axiom
annotated source: mating behavior
annotated property: definition
annotated target: Behavior related to the interactions between organisms for the purpose of mating.
source: NBO:GVG

aggressive behavior
type: Class
subclass of: emotional behavior
definition: A behavioral interaction between organisms in which one organism has the intention of inflicting damage on another individual using physical or verbal means.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: aggression
has exact synonym: aggressive behaviour
has exact synonym: agonism
has OBO namespace: behavior_ontology
xref: GO:0002118

Axiom
annotated source: aggressive behavior
annotated property: definition
annotated target: A behavioral interaction between organisms in which one organism has the intention of inflicting damage on another individual using physical or verbal means.
source: wikipedia:Aggression

jumping behavior
type: Class
subclass of: terrestrial locomotory behavior
definition: "Behavior relate to the usually upward movement off the ground or other surface through sudden muscular effort in the legs." [GO:0007630]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: jump
has OBO namespace: behavior_ontology
xref: GO:0007630

biting
type: Class
subclass of: jaw movement
definition: The act of seizing with teeth or jaws an object or organism so as to grip or break the surface covering [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: bite
has OBO namespace: behavior_ontology

fear/anxiety related behavior
type: Class
subclass of: emotional behavior
subclass of: stress related behavior
definition: Emotional behavior related to fear or anxiety.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: fear/anxiety related behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: fear/anxiety related behavior
annotated property: definition
annotated target: Emotional behavior related to fear or anxiety.
source: NBO:GVG

licking
type: Class
subclass of: tongue movement
definition: The act of stroking or touching with the tongue [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: lick
has OBO namespace: behavior_ontology

head movement
type: Class
subclass of: body part movement
definition: A change in place or position of the portion of the organism containing the brain, mouth and main sense organs [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: move head
has OBO namespace: behavior_ontology

learning behavior
type: Class
subclass of: learning and/or memory behavior
definition: Behavior associated with any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: learning behaviour
has OBO namespace: behavior_ontology
xref: GO:0007612

Axiom
annotated source: learning behavior
annotated property: definition
annotated target: Behavior associated with any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
source: wikipedia:Learning

head shaking
type: Class
subclass of: head movement
subclass of: shaking
definition: Movement of the head in the horizontal plane.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: shake head
has OBO namespace: behavior_ontology

Axiom
annotated source: head shaking
annotated property: definition
annotated target: Movement of the head in the horizontal plane.
source: NBO:GVG

sleeping behavior
type: Class
subclass of: sleep
subclass of: rhythmic behavior
definition: Behavior related to the readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0030431

Axiom
annotated source: sleeping behavior
annotated property: definition
annotated target: Behavior related to the readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
source: NBO:GVG

seizures
type: Class
subclass of: seizures/epilepsy
definition: An uncontrolled, paroxysmal neuronal discharge in any part of the brain; it may cause physical or mental symptoms and may be convulsive or nonconvulsive
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: epileptic seizure
has exact synonym: unprovoked seizure
has OBO namespace: behavior_ontology

Axiom
annotated source: seizures
annotated property: definition
annotated target: An uncontrolled, paroxysmal neuronal discharge in any part of the brain; it may cause physical or mental symptoms and may be convulsive or nonconvulsive
source: NBO:GVG

head rotation
type: Class
subclass of: head movement
definition: The act of moving the head in a plane, circularly, pivoting at the neck [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: rotate head
has OBO namespace: behavior_ontology

grooming behavior
type: Class
subclass of: behavior process
definition: The act of using body parts to pick at, rub and or remove material from exterior covering, e.g., fur, scales, feathers, skin [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: groom
has exact synonym: grooming behaviour
has OBO namespace: behavior_ontology
has related synonym: hygiene
xref: GO:0007625

akinesia
type: Class
subclass of: locomotory behavior phenotype
definition: Absence of voluntary movement.
date: 2011-04-14T12:59:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: akinesia
annotated property: definition
annotated target: Absence of voluntary movement.
source: NBO:GVG

bradykinesia
type: Class
subclass of: locomotory behavior phenotype
definition: Reduction of voluntary movement.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: hypokinesia
has OBO namespace: behavior_ontology

Axiom
annotated source: bradykinesia
annotated property: definition
annotated target: Reduction of voluntary movement.
source: NBO:GVG

hyperactivity
type: Class
subclass of: voluntary movement behavior phenotype
definition: A kinesthetic behavior which relatively increased.
date: 2011-04-14T01:09:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000752
xref: MP:0001399

Axiom
annotated source: hyperactivity
annotated property: definition
annotated target: A kinesthetic behavior which relatively increased.
source: NBO:GVG

hypoactivity
type: Class
subclass of: voluntary movement behavior phenotype
definition: A kinesthetic behavior which relatively decreased.
date: 2011-04-14T01:09:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0001402

Axiom
annotated source: hypoactivity
annotated property: definition
annotated target: A kinesthetic behavior which relatively decreased.
source: NBO:GVG

paralysis
type: Class
subclass of: locomotory behavior phenotype
definition: "Loss of power of voluntary movement in a muscle through injury or disease of its nerve supply." [JAX:<new dbxref>]
date: 2011-04-14T01:18:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0003470
xref: MP:0000753

carpoptosis
type: Class
subclass of: paralysis
definition: "Paralysis of the extensors of the wrist and fingers." [JAX:<new dbxref>]
date: 2011-04-14T01:19:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0005162
comment: Carpoptosis is most often caused by a lesion of the radial nerve.

sexual activity
type: Class
subclass of: reproductive behavior
definition: Behaviour related to the activity which primary purpose is the sexual reproduction.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
has related synonym: sexual actions

Axiom
annotated source: sexual activity
annotated property: definition
annotated target: Behaviour related to the activity which primary purpose is the sexual reproduction.
source: NBO:GVG

emission behavior
type: Class
subclass of: behavior process
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavioral control of production of sound
type: Class
subclass of: emission behavior
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: produce sound
has OBO namespace: behavior_ontology

vocalization behavior
type: Class
subclass of: behavioral control of production of sound
definition: A behavior in which an organism produces sounds by a mechanism involving its respiratory system.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: vocalization behaviour
has exact synonym: vocalize
has OBO namespace: behavior_ontology

Axiom
annotated source: vocalization behavior
annotated property: definition
annotated target: A behavior in which an organism produces sounds by a mechanism involving its respiratory system.
source: NBO:GVG

behavioral control of excretion
type: Class
subclass of: emission behavior
definition: The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007588

Axiom
annotated source: behavioral control of excretion
annotated property: definition
annotated target: The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
source: wikipedia:Excretion

behavioral control of defecation
type: Class
equivalent class: Class
  intersection of: behavioral control of excretion
  intersection of: Restriction
    on property: is_about
    some values from: defecation
subclass of: behavioral control of excretion
subclass of: Restriction
  on property: is_about
  some values from: defecation
definition: The behavioral control of defecation. [wikipedia:defecation]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavioral control of urination
type: Class
equivalent class: Class
  intersection of: behavioral control of excretion
  intersection of: Restriction
    on property: is_about
    some values from: micturition
subclass of: behavioral control of excretion
subclass of: Restriction
  on property: is_about
  some values from: micturition
definition: Excretion behaviour that controls liquid waste expulsion.
contributor: https://orcid.org/0000-0002-4277-2151
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: micturition
has exact synonym: urinate
has OBO namespace: behavior_ontology
xref: GO:0060073

Axiom
annotated source: behavioral control of urination
annotated property: definition
annotated target: Excretion behaviour that controls liquid waste expulsion.
source: wikipedia:urination

behavioral control of external secretion
type: Class
equivalent class: Class
  intersection of: emission behavior
  intersection of: Restriction
    on property: is_about
    some values from: body fluid secretion
subclass of: emission behavior
subclass of: Restriction
  on property: is_about
  some values from: body fluid secretion
definition: Behavior associated with and resulting in the production and subsequent release of any substance or product elaborated, and released by a cell or gland [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: secrete
has OBO namespace: behavior_ontology

behavioral control of lacrimation
type: Class
equivalent class: Class
  intersection of: behavioral control of external secretion
  intersection of: Restriction
    on property: by_means
    some values from: UBERON_0001817
  intersection of: Restriction
    on property: is_about
    some values from: tear secretion
subclass of: behavioral control of external secretion
subclass of: Restriction
  on property: by_means
  some values from: UBERON_0001817
subclass of: Restriction
  on property: is_about
  some values from: tear secretion
definition: The regulated release of the aqueous layer of the tear film from the lacrimal glands.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: tear release
has exact synonym: tear secretion
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral control of lacrimation
annotated property: definition
annotated target: The regulated release of the aqueous layer of the tear film from the lacrimal glands.
source: wikipedia:lacrimation

bonding behavior
type: Class
subclass of: attraction-related behavior
definition: A behavior that occurs between two individuals, such as parent and child, and involves an emotional attachment that implies a special and focused relationship.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: forming of peer relationship
has OBO namespace: behavior_ontology

Axiom
annotated source: bonding behavior
annotated property: definition
annotated target: A behavior that occurs between two individuals, such as parent and child, and involves an emotional attachment that implies a special and focused relationship.
has db xref: PMID:29327315

parental behavior
type: Class
subclass of: social behavior
definition: Behavior associated with protection, or assisting growth and development of young. [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0060746

brooding behavior
type: Class
subclass of: protection of offspring behavior
definition: Behavior that serves to regulate the temperature around offspring.[NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: thermoregulation of offspring
has OBO namespace: behavior_ontology

weaning behavior
type: Class
subclass of: parental behavior
definition: Parental behavior that promotes the breaking of an offspring's dependence on parental resources.
contributor: https://orcid.org/0000-0002-4277-2151
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: weaning behaviour
has OBO namespace: behavior_ontology
source: Immelmann K, Beer C. A dictionary of ethology. Harvard University Press; 1989.
comment: Especially food resources, and we know that many male birds provide offspring food.

Axiom
annotated source: weaning behavior
annotated property: definition
annotated target: Parental behavior that promotes the breaking of an offspring's dependence on parental resources.
has db xref: ISBN:0674205065

protection of offspring behavior
type: Class
subclass of: parental behavior
subclass of: protective behavior
definition: Behavior related the protection of offspring.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: protection of offspring
has OBO namespace: behavior_ontology

Axiom
annotated source: protection of offspring behavior
annotated property: definition
annotated target: Behavior related the protection of offspring.
source: NBO:SD

social play
type: Class
subclass of: social behavior
subclass of: playing behavior
definition: "Play behavior that is associated with the socialization of an individual into the group." [web:http\://www.bio.davidson.edu/people/vecase/behavior/Spring2009/Sacco/Pages/Play%20Fighting.html]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has alternative id: NBO:0000625
has exact synonym: social playing behaviour
has OBO namespace: behavior_ontology

thermoregulation behavior
type: Class
subclass of: motivation behavior
definition: Behavior related to the actions by which an organism modulates its internal body temperature.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: thermoregulation behavior
annotated property: definition
annotated target: Behavior related to the actions by which an organism modulates its internal body temperature.
source: NBO:GVG

huddling behavior
type: Class
subclass of: thermoregulation behavior
definition: Behavior associated with two or more individuals' achieving or maintaining close and extensive bodily contact; to nestle closely with another [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: huddle
has OBO namespace: behavior_ontology

basking behavior
type: Class
subclass of: thermoregulation behavior
definition: Exposure of body to sunlight, either by modification of body posture, by movement to specific areas or both [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: basking
has exact synonym: sunning
has exact synonym: sunning behavior
has OBO namespace: behavior_ontology

suckling behavior
type: Class
subclass of: feeding behavior
definition: Specific actions of a newborn or infant mammal that result in the derivation of nourishment from the breast.
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has alternative id: NBO:0000046
has exact synonym: nursing behaviour
has exact synonym: suckling behaviour
has OBO namespace: behavior_ontology
xref: GO:0001967

Axiom
annotated source: suckling behavior
annotated property: definition
annotated target: Specific actions of a newborn or infant mammal that result in the derivation of nourishment from the breast.
source: GOC:dph

running behavior
type: Class
subclass of: terrestrial locomotory behavior
definition: The act of locomoting on limbs with body off the ground such that periodically none of the limbs are touching the ground [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: run
has OBO namespace: behavior_ontology

walking behavior
type: Class
subclass of: terrestrial locomotory behavior
definition: The act of locomoting on limbs with body off the ground such that at least one limb is always touching the ground [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: walking
has OBO namespace: behavior_ontology
xref: GO:0007628

scratching
type: Class
subclass of: grooming behavior
definition: The act of dragging claws or nails over a surface [NBO:AC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: scratch
has exact synonym: scratching behavior
has OBO namespace: behavior_ontology

nuzzling
type: Class
subclass of: attraction-related behavior
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

copulation
type: Class
subclass of: sexual activity
definition: Male's insertion of sperm-transfer organ into the body of the female [NBO:SMAC]
date: 2011-04-14T01:03:39Z
created by: George Gkoutos
has exact synonym: copulate
has OBO namespace: behavior_ontology

forelimb paralysis
type: Class
subclass of: paralysis
definition: Loss of power of voluntary movement in muscles of the forelimb through injury or disease of it or its nerve supply.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0000756

Axiom
annotated source: forelimb paralysis
annotated property: definition
annotated target: Loss of power of voluntary movement in muscles of the forelimb through injury or disease of it or its nerve supply.
source: JAX:

bathing behavior
type: Class
subclass of: grooming behavior
definition: Behavior related to the washing or cleansing of the body in a fluid, usually water or an aqueous solution.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: bathe
has exact synonym: bathing behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: bathing behavior
annotated property: definition
annotated target: Behavior related to the washing or cleansing of the body in a fluid, usually water or an aqueous solution.
source: wikipedia:Bathing

regulation of eating behavior
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: food consumption
subclass of: regulation of feeding behavior
subclass of: Restriction
  on property: regulates
  some values from: food consumption
definition: A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of food.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: eating behaviour
has OBO namespace: behavior_ontology
xref: GO:0042755

Axiom
annotated source: regulation of eating behavior
annotated property: definition
annotated target: A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of food.
source: NBO:GVG

regulation of drinking behavior
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: liquid consumption
subclass of: regulation of feeding behavior
subclass of: Restriction
  on property: regulates
  some values from: liquid consumption
definition: A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of liquids.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: drinking behaviour
has OBO namespace: behavior_ontology
xref: GO:0042756

Axiom
annotated source: regulation of drinking behavior
annotated property: definition
annotated target: A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of liquids.
source: NBO:GVG

consciousness behavior
type: Class
subclass of: behavior process
definition: Behavior related to a variety of aspects of the relationship between the mind and the world with which it interacts.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: consciousness behavior
annotated property: definition
annotated target: Behavior related to a variety of aspects of the relationship between the mind and the world with which it interacts.
source: wikipedia:Consciousness

wakefulness
type: Class
subclass of: being conscious
definition: "Behavior related to the state of being conscious and engages in a coherent cognitive and behavior responses to the external world." [NBO:SD, wikipedia:Wakefulness]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

asleep
type: Class
subclass of: sleeping behavior phenotype
definition: Behavior related to reduced or absent consciousness, relatively suspended sensory activity, and inactivity of nearly all voluntary muscles.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: asleep
annotated property: definition
annotated target: Behavior related to reduced or absent consciousness, relatively suspended sensory activity, and inactivity of nearly all voluntary muscles.
source: wikipedia:Asleep

shaking
type: Class
subclass of: body part movement
definition: Repetitive movement of a body part.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: shaking
annotated property: definition
annotated target: Repetitive movement of a body part.
source: NBO:GVG

swaying
type: Class
subclass of: whole body movement
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

tilting
type: Class
subclass of: whole body movement
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

fossorial locomotion behavior
type: Class
subclass of: locomotory behavior
definition: Behavior related to the movement facilitated by the generation of hole or tunnel dug into the ground.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: burrowing
has exact synonym: burrowing behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: fossorial locomotion behavior
annotated property: definition
annotated target: Behavior related to the movement facilitated by the generation of hole or tunnel dug into the ground.
source: NBO:GVG

chewing
type: Class
subclass of: jaw movement
definition: The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: chew
has exact synonym: gnaw
has exact synonym: mastication
has OBO namespace: behavior_ontology

yawning
type: Class
subclass of: jaw movement
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

playing behavior
type: Class
subclass of: behavior process
definition: A very broad category including the partial or complete performance of adult functional behaviors in non-functional contexts, as well as interactive behaviors peculiar to immature animals [NBO:AC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: play
has OBO namespace: behavior_ontology

locomotor play
type: Class
subclass of: playing behavior
definition: Undirected behavior involving exercise and coordination, and often associated with repetition and 'practice' of adult behavior patterns in a non-functional context [NBO:AC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: exercise
has exact synonym: motor development playing behaviour
has exact synonym: motor play
has OBO namespace: behavior_ontology
comment: Many different actions are included in locomotor play. Some of the actions include a vertical leap, running in circles, chasing an animals own tail, lolloping, bouncing, bucking, rolling, whirling, dangling, spinning, back flips, hand stands, somersaults, and hanging upside down. The vertical leap is seen in mammals like in primates, hares, and mice. Along with running and bouncing, the vertical leap is important for strengthening leg muscles for self defense, escaping, or chasing. Activities like dangling and hanging upside down are important for improving climbing ability. These many different examples of locomotor play are important in strengthening muscles and improving motor skills. By participating in locomotor play, individuals will be able to improve skills like fighting, hunting, fleeing, and climbing.

courtship behavior
type: Class
subclass of: mating behavior
definition: The behavioral interactions between organisms for the purpose of attracting sexual partners.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: courtship
has exact synonym: courtship behaviour
has OBO namespace: behavior_ontology
xref: GO:0007619

Axiom
annotated source: courtship behavior
annotated property: definition
annotated target: The behavioral interactions between organisms for the purpose of attracting sexual partners.
source: GOC:dph

post-mating behavior
type: Class
subclass of: reproductive behavior
definition: Behavior related to the specific actions or reactions of an organism following mating.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has alternative id: NBO:0000325
has exact synonym: post mating behaviour
has exact synonym: post-copulatory behavior
has exact synonym: post-mating behaviour
has OBO namespace: behavior_ontology
xref: GO:0045297

Axiom
annotated source: post-mating behavior
annotated property: definition
annotated target: Behavior related to the specific actions or reactions of an organism following mating.
source: GOC:bf

feeding behavior
type: Class
equivalent class: Class
  intersection of: consumption behavior
  intersection of: Class
    union of: Restriction
      on property: has_participant
      some values from: food
    union of: Restriction
      on property: has_participant
      some values from: PATO_0001548
subclass of: consumption behavior
definition: The act of bringing an object or substance into the body by swallowing, surrounding or absorbing it [NBO:SMAC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: feeding behaviour
has OBO namespace: behavior_ontology
xref: GO:0007631

sitting down
type: Class
subclass of: whole body movement
definition: The act of moving the body core lower, closer to the ground [NOB:SMAC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: sit down
has OBO namespace: behavior_ontology

standing up
type: Class
subclass of: whole body movement
definition: The act of moving the body core higher, away from the ground [NBO:SMAC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: stand up
has OBO namespace: behavior_ontology

writhing
type: Class
subclass of: whole body movement
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: writhe
has OBO namespace: behavior_ontology

circadian behavior
type: Class
equivalent class: Class
  intersection of: rhythmic behavior
  intersection of: Restriction
    on property: is_about
    some values from: circadian rhythm
subclass of: rhythmic behavior
subclass of: Restriction
  on property: is_about
  some values from: circadian rhythm
definition: Behavior related to any biological process in an organism that recurs with a regularity of approximately 24 hours.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0048512

Axiom
annotated source: circadian behavior
annotated property: definition
annotated target: Behavior related to any biological process in an organism that recurs with a regularity of approximately 24 hours.
source: NBO:GVG

depression behavior
type: Class
subclass of: emotional behavior
definition: Emotional behavior related to a state of low mood and aversion to activity.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: depression related behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: depression behavior
annotated property: definition
annotated target: Emotional behavior related to a state of low mood and aversion to activity.
source: wikipedia:Depression

novelty response behavior
type: Class
subclass of: emotional behavior
definition: Behavior related to the exploration/investigation of a novel object, situation or environment.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: novelty response behavior
annotated property: definition
annotated target: Behavior related to the exploration/investigation of a novel object, situation or environment.
source: NBO:GVG

antipredation behavior
type: Class
subclass of: protective behavior
definition: Behavior related to defence against predation or predators.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: antipredator behavior
has OBO namespace: behavior_ontology

Axiom
annotated source: antipredation behavior
annotated property: definition
annotated target: Behavior related to defence against predation or predators.
source: NBO:GVG

acute stress response
type: Class
subclass of: antipredation behavior
subclass of: behavioral alarm
definition: Behavior related to the preparation of the body to \"fight\" or \"flee\" from perceived attack, harm or threat.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: fight-or-flight response
has exact synonym: fight-or-flight-or-freeze response
has OBO namespace: behavior_ontology

Axiom
annotated source: acute stress response
annotated property: definition
annotated target: Behavior related to the preparation of the body to \"fight\" or \"flee\" from perceived attack, harm or threat.
source: NBO:GVG

predator behavior
type: Class
subclass of: physical aggression behavior
subclass of: hunger motivation behavior
definition: A physical aggression behavior involving attack on prey by a predator.
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: predatory aggression
has exact synonym: predatory aggressive behaviour
has OBO namespace: behavior_ontology
xref: GO:0002120

Axiom
annotated source: predator behavior
annotated property: definition
annotated target: A physical aggression behavior involving attack on prey by a predator.
source: NBO:GVG

threatening predator behavior
type: Class
subclass of: antipredation behavior
definition: Behavior directed at a predator that signifies hostility and predicts an increased probability of attack [NBO:SMAC]
date: 2011-04-14T01:20:02Z
created by: George Gkoutos
has exact synonym: threaten predator
has OBO namespace: behavior_ontology

fear-related behavior
type: Class
subclass of: fear/anxiety related behavior
definition: An emotional behavior related to a feeling of uneasiness or nervousness triggered by a specified triggering stimulus such as pain or the threat of danger.
date: 2011-03-31T10:00:42Z
created by: George Gkoutos
has exact synonym: fear-related behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: fear-related behavior
annotated property: definition
annotated target: An emotional behavior related to a feeling of uneasiness or nervousness triggered by a specified triggering stimulus such as pain or the threat of danger.
source: NBO:GVG

anxiety-related behavior
type: Class
subclass of: fear/anxiety related behavior
definition: An emotional behavior related to a feeling of uneasiness or nervousness triggered by an identifiable triggering stimulus.
date: 2011-03-31T10:01:25Z
created by: George Gkoutos
has exact synonym: anxiety-related behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: anxiety-related behavior
annotated property: definition
annotated target: An emotional behavior related to a feeling of uneasiness or nervousness triggered by an identifiable triggering stimulus.
source: NBO:GVG

fear behavior towards objects
type: Class
subclass of: fear-related behavior
definition: An emotional behavior related to a feeling of uneasiness or nervousness in respect to an object.
date: 2011-03-31T10:16:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fear behavior towards objects
annotated property: definition
annotated target: An emotional behavior related to a feeling of uneasiness or nervousness in respect to an object.
source: NBO:GVG

fear behavior towards situation/environment
type: Class
subclass of: fear-related behavior
subclass of: exploration behavior
definition: An emotional behavior related to a feeling of uneasiness or nervousness in respect to a particular situation or environment.
date: 2011-03-31T10:18:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fear behavior towards situation/environment
annotated property: definition
annotated target: An emotional behavior related to a feeling of uneasiness or nervousness in respect to a particular situation or environment.
source: NBO:GVG

fear behavior towards living things
type: Class
subclass of: fear-related behavior
definition: An emotional behavior related to a feeling of uneasiness or nervousness in respect to a living thing.
date: 2011-03-31T10:18:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fear behavior towards living things
annotated property: definition
annotated target: An emotional behavior related to a feeling of uneasiness or nervousness in respect to a living thing.
source: NBO:GVG

agoraphobia behavior
type: Class
subclass of: phobia
definition: A phobia characterised by fear of open spaces.
date: 2011-03-31T10:18:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000756

Axiom
annotated source: agoraphobia behavior
annotated property: definition
annotated target: A phobia characterised by fear of open spaces.
source: NBO:GVG

response to novel environment
type: Class
subclass of: novelty response behavior
definition: Behavior related to the exploration/investigation of a novel environment.
date: 2011-03-31T10:22:03Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: response to novel environment
annotated property: definition
annotated target: Behavior related to the exploration/investigation of a novel environment.
source: NBO:GVG

response to novel object
type: Class
subclass of: novelty response behavior
definition: Behavior related to the exploration/investigation of a novel obhject.
date: 2011-03-31T10:23:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: response to novel object
annotated property: definition
annotated target: Behavior related to the exploration/investigation of a novel obhject.
source: NBO:GVG

response to novel odor
type: Class
subclass of: novelty response behavior
definition: Behavior related to the exploration/investigation of a novel odor.
date: 2011-03-31T10:24:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: response to novel odor
annotated property: definition
annotated target: Behavior related to the exploration/investigation of a novel odor.
source: NBO:GVG

exploration behavior
type: Class
subclass of: response to novel environment
date: 2011-03-31T10:28:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0035640

retropulsion
type: Class
subclass of: walking behavior
definition: Moving backwards.
date: 2011-03-31T10:32:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: retropulsion
annotated property: definition
annotated target: Moving backwards.
source: NBO:GVG

fear-related retropulsion
type: Class
subclass of: fear-related behavior
subclass of: exploration behavior
subclass of: retropulsion
definition: Moving backwards in response to a fear stimulus.
date: 2011-03-31T10:36:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fear-related retropulsion
annotated property: definition
annotated target: Moving backwards in response to a fear stimulus.
source: NBO:GVG

coping behavior
type: Class
subclass of: stress related behavior
definition: Behavioral response to the presidency of the stressor where it becomes necessary to attempt some means of coping with the stress.
date: 2011-03-31T10:49:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: coping behavior
annotated property: definition
annotated target: Behavioral response to the presidency of the stressor where it becomes necessary to attempt some means of coping with the stress.
source: NBO:GVG

aggressive behavior towards humans
type: Class
subclass of: aggressive behavior towards animals
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards humans.
date: 2011-03-31T10:50:52Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards humans
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards humans
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards humans.
source: NBO:GVG

aggressive behavior towards animals
type: Class
subclass of: aggressive behavior by intent
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards animals.
date: 2011-03-31T10:51:12Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards animals
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards animals
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards animals.
source: NBO:GVG

aggressive behavior towards objects
type: Class
subclass of: aggressive behavior by intent
definition: Exhibiting a domineering, assault posture and/or hostile physical action toward any type of object.
date: 2011-03-31T10:51:33Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards objects
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards objects
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action toward any type of object.
source: NBO:GVG

aggressive behavior towards mice
type: Class
subclass of: aggressive behavior towards animals
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards mice.
date: 2011-03-31T10:51:50Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards mice
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards mice
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards mice.
source: NBO:GVG

aggressive behavior towards women
type: Class
subclass of: aggressive behavior towards humans
subclass of: aggressive behavior towards females
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards women.
date: 2011-03-31T10:52:04Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards women
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards women
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards women.
source: NBO:GVG

aggressive behavior towards men
type: Class
subclass of: aggressive behavior towards humans
subclass of: aggressive behavior towards males
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards men.
date: 2011-03-31T10:52:26Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards men
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards men
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards men.
source: NBO:GVG

aggressive behavior towards male mice
type: Class
subclass of: aggressive behavior towards mice
subclass of: aggressive behavior towards males
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards male mice.
date: 2011-03-31T10:52:56Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards male mice
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards male mice
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards male mice.
source: NBO:GVG

aggressive behavior towards female mice
type: Class
subclass of: aggressive behavior towards mice
subclass of: aggressive behavior towards females
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards female mice.
date: 2011-03-31T10:53:07Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards female mice
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards female mice
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards female mice.
source: NBO:GVG

aggressive behavior towards inanimate objects
type: Class
subclass of: aggressive behavior towards objects
definition: Exhibiting a domineering, assault posture and/or hostile physical action toward inanimate objects.
date: 2011-03-31T10:53:44Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards inanimate objects
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards inanimate objects
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action toward inanimate objects.
source: NBO:GVG

aggressive behavior towards animate objects
type: Class
subclass of: aggressive behavior towards objects
definition: Exhibiting a domineering, assault posture and/or hostile physical action toward animate objects.
date: 2011-03-31T10:53:59Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards animate objects
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards animate objects
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action toward animate objects.
contributor: https://orcid.org/0000-0002-4277-2151

aggressive behavior towards children
type: Class
subclass of: aggressive behavior towards humans
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards children.
date: 2011-03-31T10:57:11Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards children
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards children
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards children.
source: NBO:GVG

aggressive behavior towards pups
type: Class
subclass of: aggressive behavior towards mice
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards pups.
date: 2011-03-31T10:58:09Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards pups
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards pups
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards pups.
source: NBO:GVG

gender-related aggressive behavior
type: Class
subclass of: aggressive behavior towards animals
definition: Gender related exhibition of a domineering, assault posture and/or hostile physical action.
date: 2011-03-31T11:02:17Z
created by: George Gkoutos
has exact synonym: gender-related aggressive behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: gender-related aggressive behavior
annotated property: definition
annotated target: Gender related exhibition of a domineering, assault posture and/or hostile physical action.
source: NBO:GVG

aggressive behavior towards females
type: Class
subclass of: gender-related aggressive behavior
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards female animals.
date: 2011-03-31T11:03:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards females
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards female animals.
source: NBO:GVG

aggressive behavior towards males
type: Class
subclass of: gender-related aggressive behavior
definition: Exhibiting a domineering, assault posture and/or hostile physical action towards male animals.
date: 2011-03-31T11:04:03Z
created by: George Gkoutos
has exact synonym: aggressive behavior towards males
has OBO namespace: behavior_ontology

Axiom
annotated source: aggressive behavior towards males
annotated property: definition
annotated target: Exhibiting a domineering, assault posture and/or hostile physical action towards male animals.
source: NBO:GVG

impulsive behavior
type: Class
subclass of: behavior process
definition: A behavior that occur quickly without control, planning, or consideration of the consequences of that behavior.
date: 2011-03-31T11:08:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: impulsive behavior
annotated property: definition
annotated target: A behavior that occur quickly without control, planning, or consideration of the consequences of that behavior.
source: NBO:GVG

physical aggression behavior
type: Class
subclass of: aggressive behavior by means
definition: An aggressive behavior that aims to inflicting damage on another entity using physical means.
date: 2011-03-31T11:14:04Z
created by: George Gkoutos
has exact synonym: physical aggression behaviour
has exact synonym: violent behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: physical aggression behavior
annotated property: definition
annotated target: An aggressive behavior that aims to inflicting damage on another entity using physical means.
source: NBO:GVG

agonistic behavior
type: Class
subclass of: emotional behavior
subclass of: social behavior
date: 2011-03-31T11:42:15Z
created by: George Gkoutos
has exact synonym: agonism
has OBO namespace: behavior_ontology

submissive behavior
type: Class
subclass of: agonistic behavior
definition: Any behavior that tends to prevent further or future attack, often by signalling a willingness to yield or surrender [NBO:AC]
date: 2011-03-31T11:43:11Z
created by: George Gkoutos
has exact synonym: submissive behaviour
has OBO namespace: behavior_ontology

submissive behavior towards males
type: Class
subclass of: submissive behavior
definition: A behavior associated with the tendency of an organism towards being passive and willing to yield to male animals.
date: 2011-03-31T11:43:37Z
created by: George Gkoutos
has exact synonym: submissive behavior towards males
has OBO namespace: behavior_ontology

Axiom
annotated source: submissive behavior towards males
annotated property: definition
annotated target: A behavior associated with the tendency of an organism towards being passive and willing to yield to male animals.
source: NBO:GVG

submissive behavior towards females
type: Class
subclass of: submissive behavior
definition: A behavior associated with the tendency of an organism towards being passive and willing to yield to female animals.
date: 2011-03-31T11:44:14Z
created by: George Gkoutos
has exact synonym: submissive behavior towards females
has OBO namespace: behavior_ontology

Axiom
annotated source: submissive behavior towards females
annotated property: definition
annotated target: A behavior associated with the tendency of an organism towards being passive and willing to yield to female animals.
source: NBO:GVG

submissive behavior towards male mice
type: Class
subclass of: submissive behavior towards males
definition: A behavior associated with the tendency of an organism towards being passive and willing to yield towards male mice.
date: 2011-03-31T11:44:25Z
created by: George Gkoutos
has exact synonym: submissive behavior towards male mice
has OBO namespace: behavior_ontology

Axiom
annotated source: submissive behavior towards male mice
annotated property: definition
annotated target: A behavior associated with the tendency of an organism towards being passive and willing to yield towards male mice.
source: NBO:GVG

subordination behavior
type: Class
subclass of: submissive behavior
date: 2011-03-31T11:47:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

retreat behavior
type: Class
subclass of: agonistic behavior
definition: Behavior by which an animal removes itself spatially from an agonistic encounter in which it is not the winner [NBO:AC]
date: 2011-03-31T11:49:03Z
created by: George Gkoutos
has exact synonym: retreat
has exact synonym: retreat behaviour
has OBO namespace: behavior_ontology

irritability behavior
type: Class
subclass of: agonistic behavior
definition: Behavior characterized by a quick excitability to annoyance, impatience, or anger.
date: 2011-03-31T12:16:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: irritability behavior
annotated property: definition
annotated target: Behavior characterized by a quick excitability to annoyance, impatience, or anger.
source: NBO:GVG

agitation behavior
type: Class
subclass of: emotional behavior
definition: Emotional behavior related to excitement or restlessness.
date: 2011-03-31T12:22:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: agitation behavior
annotated property: definition
annotated target: Emotional behavior related to excitement or restlessness.
source: NBO:GVG

liquid consumption
type: Class
subclass of: feeding behavior
subclass of: Restriction
  on property: has_participant
  some values from: PATO_0001548
definition: A behavior associated with the intake of liquid.
date: 2011-03-31T12:40:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: liquid consumption
annotated property: definition
annotated target: A behavior associated with the intake of liquid.
source: NBO:GVG

alcohol consumption
type: Class
equivalent class: Class
  intersection of: liquid consumption
  intersection of: Restriction
    on property: has_participant
    some values from: ethanol
subclass of: liquid consumption
subclass of: Restriction
  on property: has_participant
  some values from: ethanol
definition: A drinking behavior associated with the intake of alcohol.
date: 2011-03-31T12:40:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alcohol consumption
annotated property: definition
annotated target: A drinking behavior associated with the intake of alcohol.
source: NBO:GVG

water consumption
type: Class
equivalent class: Class
  intersection of: liquid consumption
  intersection of: Restriction
    on property: has_participant
    some values from: water
subclass of: liquid consumption
subclass of: Restriction
  on property: has_participant
  some values from: water
definition: A drinking behavior associated with the intake of water.
date: 2011-03-31T12:41:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0045187

Axiom
annotated source: water consumption
annotated property: definition
annotated target: A drinking behavior associated with the intake of water.
source: NBO:GVG

liquid preference/aversion
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000161
        intersection of: Restriction
subclass of: drinking behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000161
        intersection of: Restriction
date: 2011-03-31T12:41:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

food consumption
type: Class
equivalent class: Class
  intersection of: feeding behavior
  intersection of: Restriction
    on property: has_participant
    some values from: food
subclass of: feeding behavior
subclass of: Restriction
  on property: has_participant
  some values from: food
definition: A feeding behavior associated with the intake of food.
date: 2011-03-31T12:42:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: food consumption
annotated property: definition
annotated target: A feeding behavior associated with the intake of food.
source: NBO:GVG

food preference/aversion
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000161
subclass of: eating behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000161
date: 2011-03-31T12:43:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

saccharin consumption
type: Class
equivalent class: Class
  intersection of: food consumption
  intersection of: Restriction
    on property: has_participant
    some values from: saccharin
subclass of: food consumption
subclass of: Restriction
  on property: has_participant
  some values from: saccharin
definition: A feeding behavior associated with the intake of saccharin.
date: 2011-03-31T12:50:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: saccharin consumption
annotated property: definition
annotated target: A feeding behavior associated with the intake of saccharin.
source: NBO:GVG

liquid preference
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000912
        intersection of: Restriction
subclass of: liquid preference/aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000912
        intersection of: Restriction
definition: Predilection to ingest a liquid over other substances.
date: 2011-03-31T12:55:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: liquid preference
annotated property: definition
annotated target: Predilection to ingest a liquid over other substances.
source: NBOC:GVG

liquid aversion
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000911
        intersection of: Restriction
subclass of: liquid preference/aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000911
        intersection of: Restriction
definition: Purposeful avoidance of a liquid due to dislike.
date: 2011-03-31T12:55:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: liquid aversion
annotated property: definition
annotated target: Purposeful avoidance of a liquid due to dislike.
source: NBO:GVG

alcohol aversion
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of alcohol preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000911
subclass of: liquid aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of alcohol preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000911
definition: Purposeful avoidance of liquid alcohol due to dislike. [NBO:LKSR]
date: 2011-03-31T12:55:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alcohol aversion
annotated property: definition
annotated target: Purposeful avoidance of liquid alcohol due to dislike. [NBO:LKSR]
source: NBO:GVG

alcohol preference
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of alcohol preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
subclass of: liquid preference
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of alcohol preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
definition: Predilection to ingest alcohol over other substances.
date: 2011-03-31T12:56:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alcohol preference
annotated property: definition
annotated target: Predilection to ingest alcohol over other substances.
source: NBOC:GVG

food preference
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
subclass of: food preference/aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
date: 2011-03-31T12:58:43Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

food aversion
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000911
subclass of: food preference/aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000911
date: 2011-03-31T12:59:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

saccharin preference
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of saccharin preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
subclass of: food preference
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of saccharin preference behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
date: 2011-03-31T12:59:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

mating frequency
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
subclass of: mating behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
date: 2011-03-31T02:16:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

mating preference
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: NBO_0002948
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000161
subclass of: mating behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: NBO_0002948
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000161
date: 2011-03-31T02:17:22Z
created by: George Gkoutos
has exact synonym: mate choice
has OBO namespace: behavior_ontology

mating receptivity
type: Class
subclass of: mating behavior
date: 2011-03-31T02:17:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

sexual display behavior
type: Class
subclass of: mating behavior
date: 2011-03-31T02:21:53Z
created by: George Gkoutos
has narrow synonym: mate attraction behavior
has OBO namespace: behavior_ontology

social investigation
type: Class
subclass of: social behavior
date: 2011-03-31T02:24:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

reclusive behavior
type: Class
subclass of: social behavior
date: 2011-03-31T02:25:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

maternal behavior
type: Class
subclass of: parental behavior
definition: Behavior of a mother towards her offspring.
date: 2011-03-31T02:32:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042711

Axiom
annotated source: maternal behavior
annotated property: definition
annotated target: Behavior of a mother towards her offspring.
source: NBO:GVG

paternal behavior
type: Class
subclass of: parental behavior
definition: Behavior of a father towards his offspring.
date: 2011-03-31T02:32:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042712

Axiom
annotated source: paternal behavior
annotated property: definition
annotated target: Behavior of a father towards his offspring.
source: NBO:GVG

maternal nurturing behavior
type: Class
subclass of: maternal behavior
definition: Maternal behavior related to the brining up her offspring.
date: 2011-03-31T02:33:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: maternal nurturing behavior
annotated property: definition
annotated target: Maternal behavior related to the brining up her offspring.
source: NBO:GVG

paternal nurturing behavior
type: Class
subclass of: paternal behavior
definition: Paternal behavior related to the brining up his offspring.
date: 2011-03-31T02:33:49Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: paternal nurturing behavior
annotated property: definition
annotated target: Paternal behavior related to the brining up his offspring.
source: NBO:GVG

maternal crouching
type: Class
subclass of: maternal nurturing behavior
date: 2011-03-31T02:35:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

offspring retrieval
type: Class
subclass of: protection of offspring behavior
definition: Behavior related to the parent's tendency to collect stray offspring and return them to a defined location.
date: 2011-03-31T02:42:29Z
created by: George Gkoutos
has exact synonym: retrieval
has OBO namespace: behavior_ontology

Axiom
annotated source: offspring retrieval
annotated property: definition
annotated target: Behavior related to the parent's tendency to collect stray offspring and return them to a defined location.
source: NBO:GVG

nesting behavior
type: Class
subclass of: social behavior
date: 2011-03-31T02:53:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

nest building behavior
type: Class
subclass of: nesting behavior
date: 2011-03-31T02:54:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

sleep pattern
type: Class
subclass of: sleeping behavior phenotype
date: 2011-03-31T02:59:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

rapid eye movement sleep
type: Class
equivalent class: Class
  intersection of: sleeping behavior
  intersection of: Restriction
    on property: is_about
    some values from: circadian sleep/wake cycle, REM sleep
subclass of: circadian sleep/wake cycle, REM sleep
subclass of: circadian sleep/wake cycle, sleep
subclass of: sleeping behavior
subclass of: circadian behavior
subclass of: Restriction
  on property: is_about
  some values from: circadian sleep/wake cycle, REM sleep
date: 2011-03-31T03:00:57Z
created by: George Gkoutos
has exact synonym: REM sleep
has exact synonym: paradoxical sleep
has OBO namespace: behavior_ontology

sleep duration
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
subclass of: sleeping behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
date: 2011-03-31T03:09:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

non-rapid eye movement sleep behavior
type: Class
subclass of: circadian sleep/wake cycle, non-REM sleep
subclass of: circadian sleep/wake cycle, sleep
subclass of: sleeping behavior
subclass of: circadian behavior
subclass of: Restriction
  on property: is_about
  some values from: circadian sleep/wake cycle, non-REM sleep
definition: Behavior related to all sleep stages in the circadian sleep/wake cycle other than REM sleep.
date: 2011-03-31T03:12:44Z
created by: George Gkoutos
has exact synonym: NREM sleep behavior
has OBO namespace: behavior_ontology
comment: These stages are characterized by a slowing of brain waves and other physiological functions.

Axiom
annotated source: non-rapid eye movement sleep behavior
annotated property: definition
annotated target: Behavior related to all sleep stages in the circadian sleep/wake cycle other than REM sleep.
source: NBO:GVG

REM duration
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
subclass of: rapid eye movement sleep phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
definition: Duration of REM sleep.
date: 2011-03-31T03:15:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: REM duration
annotated property: definition
annotated target: Duration of REM sleep.
source: NBO:GVG

REM frequency
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
subclass of: rapid eye movement sleep phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
date: 2011-03-31T03:15:49Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

NREM duration
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
subclass of: sleep duration
subclass of: non-rapid eye movement sleep behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001309
definition: Duration of NREM sleep.
date: 2011-03-31T03:16:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: NREM duration
annotated property: definition
annotated target: Duration of NREM sleep.
contributor: https://orcid.org/0000-0002-4277-2151

NREM frequency
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
subclass of: non-rapid eye movement sleep behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000044
date: 2011-03-31T03:16:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

circadian rhythm
type: Class
subclass of: circadian behavior
definition: Endogenously driven roughly 24-hour cycle in biochemical, physiological, or behavioral processes.
date: 2011-03-31T03:22:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007623

Axiom
annotated source: circadian rhythm
annotated property: definition
annotated target: Endogenously driven roughly 24-hour cycle in biochemical, physiological, or behavioral processes.
source: GOC:bf

circadian period
type: Class
subclass of: circadian rhythm
date: 2011-03-31T03:23:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

circadian persistence
type: Class
subclass of: circadian rhythm
date: 2011-03-31T03:23:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

circadian phase
type: Class
subclass of: circadian rhythm
date: 2011-03-31T03:24:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

memory behavior
type: Class
subclass of: learning and/or memory behavior
definition: Behavior related with the ability of an organism's ability to store, retain, and recall information and experiences.
date: 2011-04-01T01:49:03Z
created by: George Gkoutos
has exact synonym: memory behaviour
has OBO namespace: behavior_ontology
xref: GO:0007613

Axiom
annotated source: memory behavior
annotated property: definition
annotated target: Behavior related with the ability of an organism's ability to store, retain, and recall information and experiences.
source: NBO:GVG

associative learning behavior
type: Class
subclass of: social behavior
subclass of: learning behavior
definition: "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." [Wikipedia:Learning#Associative_learning]
date: 2011-04-01T01:49:32Z
created by: George Gkoutos
has exact synonym: conditional learning
has OBO namespace: behavior_ontology
xref: GO:0008306
comment: The formation of associations among stimuli and responses.

olfactory learning behavior
type: Class
subclass of: olfactory behavior
subclass of: discrimination learning
date: 2011-04-01T01:54:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0008355

visual learning behavior
type: Class
subclass of: visual behavior
subclass of: discrimination learning
date: 2011-04-01T01:54:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0008542

motor learning
type: Class
equivalent class: Class
  intersection of: associative learning behavior
  intersection of: Restriction
    on property: is_about
    some values from: motor coordination
subclass of: associative learning behavior
subclass of: Restriction
  on property: is_about
  some values from: motor coordination
date: 2011-04-01T01:56:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

spatial learning
type: Class
subclass of: associative learning behavior
date: 2011-04-01T01:57:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

vocal learning
type: Class
equivalent class: Class
  intersection of: associative learning behavior
  intersection of: Restriction
    on property: is_about
    some values from: vocalization behavior
subclass of: associative learning behavior
subclass of: Restriction
  on property: is_about
  some values from: vocalization behavior
definition: "A behavioral process whose outcome is a relatively long-lasting adaptive behavioral change whereby an organism modifies innate vocalizations to imitate or create new sounds." [GO:0042297]
date: 2011-04-01T01:58:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042297

non-associative learning
type: Class
subclass of: learning behavior
definition: A decrease in a behavioral response to a repeated stimulus.
date: 2011-04-01T03:18:40Z
created by: George Gkoutos
has exact synonym: nonassociative learning
has exact synonym: unconditional response
has OBO namespace: behavior_ontology
xref: GO:0046958

Axiom
annotated source: non-associative learning
annotated property: definition
annotated target: A decrease in a behavioral response to a repeated stimulus.
source: NBO:GVG

habituation
type: Class
subclass of: non-associative learning
definition: Gradual decrease in behavioral responses with repeated encounters of a particular stimulus, which proves of no consequence.
date: 2011-04-01T03:19:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0046959

Axiom
annotated source: habituation
annotated property: definition
annotated target: Gradual decrease in behavioral responses with repeated encounters of a particular stimulus, which proves of no consequence.
source: wikipedia:Habituation

sensitization
type: Class
subclass of: non-associative learning
definition: An increase in behavioral responses following repeated applications of a particular stimulus.
date: 2011-04-01T03:54:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sensitization
annotated property: definition
annotated target: An increase in behavioral responses following repeated applications of a particular stimulus.
source: wikipedia:Sensitization

short-term memory
type: Class
subclass of: memory storage behavior
definition: A type of memory that allows the recall of something from several seconds to as long as a minute.
date: 2011-04-01T03:59:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007614

Axiom
annotated source: short-term memory
annotated property: definition
annotated target: A type of memory that allows the recall of something from several seconds to as long as a minute.
source: NBO:GVG

long-term memory
type: Class
subclass of: memory storage behavior
definition: This type of memory, lasting hours to months, critically depends on a transfer of the information from short term memory using repeated rehearsal.
date: 2011-04-01T03:59:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007616

Axiom
annotated source: long-term memory
annotated property: definition
annotated target: This type of memory, lasting hours to months, critically depends on a transfer of the information from short term memory using repeated rehearsal.
source: NBO:GVG

sensory memory
type: Class
subclass of: memory storage behavior
definition: Report great detail about a complex stimulus immediately following its presentation. This ability forms within a few tens of milliseconds and decays again rapidly within a few hundred milliseconds.
date: 2011-04-01T03:59:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sensory memory
annotated property: definition
annotated target: Report great detail about a complex stimulus immediately following its presentation. This ability forms within a few tens of milliseconds and decays again rapidly within a few hundred milliseconds.
source: NBO:GVG

long-lasting memory
type: Class
subclass of: memory storage behavior
definition: A memory that last for months to lifetime.
date: 2011-04-01T04:00:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: long-lasting memory
annotated property: definition
annotated target: A memory that last for months to lifetime.
source: NBO:GVG

medium term memory
type: Class
subclass of: memory storage behavior
definition: A type of memory that allows the recall of something from minutes to several hours.
date: 2011-04-01T04:01:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0072375

Axiom
annotated source: medium term memory
annotated property: definition
annotated target: A type of memory that allows the recall of something from minutes to several hours.
source: NBO:GVG

declarative memory
type: Class
subclass of: long-term memory
definition: Ability to become conscious of, or declare, facts and experiences.
date: 2011-04-02T07:38:45Z
created by: George Gkoutos
has exact synonym: explicit memory
has OBO namespace: behavior_ontology
comment: Encoded by the hippocampus, entorhinal cortex, and perirhinal cortex but store possibly in the medial temporal lobe.

Axiom
annotated source: declarative memory
annotated property: definition
annotated target: Ability to become conscious of, or declare, facts and experiences.
source: NBO:GVG

semantic memory
type: Class
subclass of: declarative memory
definition: Ability to consciously recall knowledge of facts that are independent of a specific time and place.
date: 2011-04-02T07:40:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Medial temporal lobe, diencephalon.

Axiom
annotated source: semantic memory
annotated property: definition
annotated target: Ability to consciously recall knowledge of facts that are independent of a specific time and place.
source: NBO:GVG

episodic memory
type: Class
subclass of: declarative memory
definition: Ability to explicitly recall information about a specific event that has occurred at a specific time and place.
date: 2011-04-02T07:41:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Medial temporal lobe, diencephalon.

Axiom
annotated source: episodic memory
annotated property: definition
annotated target: Ability to explicitly recall information about a specific event that has occurred at a specific time and place.
source: NBO:GVG

non-declarative memory
type: Class
subclass of: long-term memory
definition: Non-declarative memory type of memory, which does not need to involve conscious awareness in the act of recollection.
date: 2011-04-02T07:42:37Z
created by: George Gkoutos
has alternative id: NBO:0000189
has exact synonym: implicit memory
has exact synonym: procedural memory
has OBO namespace: behavior_ontology
comment: Encoded and probably stored by the cerebellum and the striatum but store in the amygdala.

Axiom
annotated source: non-declarative memory
annotated property: definition
annotated target: Non-declarative memory type of memory, which does not need to involve conscious awareness in the act of recollection.
source: NBO:GVG

motor memory
type: Class
subclass of: non-declarative memory
definition: Consolidating a specific motor task into memory through repetition.
date: 2011-04-02T07:54:40Z
created by: George Gkoutos
has exact synonym: muscle memory
has OBO namespace: behavior_ontology
comment: Depends on the cerebellum and basal ganglia.

Axiom
annotated source: motor memory
annotated property: definition
annotated target: Consolidating a specific motor task into memory through repetition.
source: NBO:GVG

emotional memory
type: Class
subclass of: long-term memory
definition: "A type of memory associated with emotional experiences." [wikipedia:http\://www.scholarpedia.org/article/Emotional_memory]
date: 2011-04-02T07:59:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

prospective memory
type: Class
subclass of: declarative memory
definition: Remembering to perform an intended action.
date: 2011-04-02T08:16:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: prospective memory
annotated property: definition
annotated target: Remembering to perform an intended action.
source: NBO:GVG

event-based prospective memory
type: Class
subclass of: prospective memory
definition: Remembering to perform an intended action in respect to a particular event.
date: 2011-04-02T08:19:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: event-based prospective memory
annotated property: definition
annotated target: Remembering to perform an intended action in respect to a particular event.
source: NBO:GVG

time-based prospective memory
type: Class
subclass of: prospective memory
definition: Remembering to perform an intended action in respect to a particular time reference.
date: 2011-04-02T08:19:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: time-based prospective memory
annotated property: definition
annotated target: Remembering to perform an intended action in respect to a particular time reference.
source: NBO:GVG

autobiographical memory
type: Class
subclass of: episodic memory
definition: A type of memory for particular events within one's own life.
date: 2011-04-02T08:27:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: autobiographical memory
annotated property: definition
annotated target: A type of memory for particular events within one's own life.
source: NBO:GVG

visual memory
type: Class
subclass of: declarative memory
definition: "Ability to store and retrieve previously experienced visual sensations and perceptions when the stimuli that originally evoked them are no longer present." [wikipedia:Visual_memory]
date: 2011-04-02T08:33:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

iconic memory
type: Class
subclass of: sensory memory
date: 2011-04-02T08:37:43Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

eidetic memory
type: Class
subclass of: sensory memory
definition: "The ability to recall images, sounds, or objects in memory with extreme precision and in abundant volume." [wikipedia:Eidetic_memory]
date: 2011-04-02T08:39:24Z
created by: George Gkoutos
has exact synonym: photographic memory
has OBO namespace: behavior_ontology

topographic memory
type: Class
subclass of: declarative memory
definition: Ability to orient oneself in space, to recognize and follow an itinerary, or to recognize familiar places.
date: 2011-04-02T08:42:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: topographic memory
annotated property: definition
annotated target: Ability to orient oneself in space, to recognize and follow an itinerary, or to recognize familiar places.
source: NBO:GVG

priming
type: Class
subclass of: memory retrieval behavior
definition: An implicit memory effect in which exposure to a stimulus influences response to a later stimulus.
date: 2011-04-02T08:50:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: priming
annotated property: definition
annotated target: An implicit memory effect in which exposure to a stimulus influences response to a later stimulus.
source: NBO:GVG

direct priming
type: Class
subclass of: priming
date: 2011-04-02T08:55:04Z
created by: George Gkoutos
has exact synonym: repetition
has OBO namespace: behavior_ontology

semantic priming
type: Class
subclass of: priming
definition: A type of priming where the prime and the target are from the same semantic category and share features.
date: 2011-04-02T08:56:35Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: semantic priming
annotated property: definition
annotated target: A type of priming where the prime and the target are from the same semantic category and share features.
source: NBO:GVG

associative priming
type: Class
subclass of: priming
definition: A type of priming where the target is a word that has a high probability of appearing with the prime, and is \"associated\" with it but not necessarily related in semantic features.
date: 2011-04-02T08:57:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: associative priming
annotated property: definition
annotated target: A type of priming where the target is a word that has a high probability of appearing with the prime, and is \"associated\" with it but not necessarily related in semantic features.
source: NBO:GVG

response priming
type: Class
subclass of: priming
date: 2011-04-02T08:58:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

conceptual priming
type: Class
subclass of: priming
definition: A type of priming based on the meaning of a stimulus and is enhanced by semantic task.
date: 2011-04-02T08:59:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: conceptual priming
annotated property: definition
annotated target: A type of priming based on the meaning of a stimulus and is enhanced by semantic task.
source: NBO:GVG

perceptual priming
type: Class
subclass of: priming
definition: A type priming based on the form of the stimulus and is enhanced by the match between the early and later stimuli.
date: 2011-04-02T09:00:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: perceptual priming
annotated property: definition
annotated target: A type priming based on the form of the stimulus and is enhanced by the match between the early and later stimuli.
source: NBO:GVG

sensory adaptation
type: Class
subclass of: habituation
definition: Change in the responsiveness of a sensory system when confronted with a constant stimulus.
date: 2011-04-02T09:07:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sensory adaptation
annotated property: definition
annotated target: Change in the responsiveness of a sensory system when confronted with a constant stimulus.
source: NBO:GVG

classical conditioning
type: Class
subclass of: associative learning behavior
definition: A form of associative learning that requires an unconditional reflex, where an unconditional stimulus (US)brings about an automatic, unlearned (unconditional) response (UR). If a neutral stimulus (NS) tends to precede it, an association is made and the conditional response (CR) becomes transferred onto the (previously neutral) conditional strimulus (CS); a conditional reflex has been learned.
date: 2011-04-03T08:57:28Z
created by: George Gkoutos
has exact synonym: Pavlovian conditioning
has exact synonym: respondent conditioning
has OBO namespace: behavior_ontology

Axiom
annotated source: classical conditioning
annotated property: definition
annotated target: A form of associative learning that requires an unconditional reflex, where an unconditional stimulus (US)brings about an automatic, unlearned (unconditional) response (UR). If a neutral stimulus (NS) tends to precede it, an association is made and the conditional response (CR) becomes transferred onto the (previously neutral) conditional strimulus (CS); a conditional reflex has been learned.
source: NBO:GVG

fear conditioning
type: Class
equivalent class: Class
  intersection of: classical conditioning
  intersection of: Restriction
    on property: is_about
    some values from: fear-related behavior
subclass of: emotional conditioning
subclass of: Restriction
  on property: is_about
  some values from: fear-related behavior
definition: A type of associative learning that allows organisms to acquire affective responses, such as fear, in situations where a particular context or stimulus is predictably elicits fear via an aversive context.
date: 2011-04-03T08:58:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fear conditioning
annotated property: definition
annotated target: A type of associative learning that allows organisms to acquire affective responses, such as fear, in situations where a particular context or stimulus is predictably elicits fear via an aversive context.
source: NBO:GVG

avoidance learning behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-03T09:01:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

conditioned taste aversion
type: Class
subclass of: classical conditioning
date: 2011-04-03T09:04:57Z
created by: George Gkoutos
has exact synonym: Garcia conditioning
has OBO namespace: behavior_ontology
xref: GO:0001661

operant conditioning behavior
type: Class
subclass of: associative learning behavior
definition: "Operant conditioning is the use of a behavior's antecedent and/or its consequence to influence the occurrence and form of behavior." [wikipedia:Operant_conditioning]
date: 2011-04-03T09:05:54Z
created by: George Gkoutos
has exact synonym: instrumental conditioning
has exact synonym: instrumental learning
has OBO namespace: behavior_ontology
xref: GO:0035106
comment: Operant conditioning is distinguished from classical conditioning in that operant conditioning deals with the modification of "voluntary behavior" or operant behavior.

imprinting behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-03T09:08:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

latent learning behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-03T09:11:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

observational learning
type: Class
subclass of: social learning
date: 2011-04-03T09:11:31Z
created by: George Gkoutos
has exact synonym: modeling
has exact synonym: vicarious learning
has OBO namespace: behavior_ontology

language learning behavior
type: Class
equivalent class: Class
  intersection of: learning behavior
  intersection of: Restriction
    on property: is_about
    some values from: language communication behavior
subclass of: learning behavior
subclass of: Restriction
  on property: is_about
  some values from: language communication behavior
date: 2011-04-03T09:11:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

active avoidance learning behavior
type: Class
subclass of: avoidance learning behavior
definition: Avoidance learning when the action occurs.
date: 2011-04-04T03:22:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: active avoidance learning behavior
annotated property: definition
annotated target: Avoidance learning when the action occurs.
source: NBO:GVG

passive avoidance learning behavior
type: Class
subclass of: avoidance learning behavior
definition: Avoidance learning when no action occurs.
date: 2011-04-04T03:22:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: passive avoidance learning behavior
annotated property: definition
annotated target: Avoidance learning when no action occurs.
source: NBO:GVG

escape learning behavior
type: Class
subclass of: avoidance learning behavior
definition: Avoid a situation completely.
date: 2011-04-04T03:25:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: escape learning behavior
annotated property: definition
annotated target: Avoid a situation completely.
source: NBO:GVG

social learning
type: Class
subclass of: associative learning behavior
definition: Associative learning behavior that arises from observing or interacting with another individual.
contributor: https://orcid.org/0000-0002-4277-2151
date: 2011-04-04T03:34:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
source: Social learning in animals
comment: Original definition: "The sociological process of training individuals in a society to act or respond in a manner generally approved by the society in general and peer groups within society." [wikipedia:Social_conditioning]

conditioned emotional response
type: Class
equivalent class: Class
  intersection of: associative learning behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: emotional conditioning
subclass of: emotional behavior
subclass of: associative learning behavior
subclass of: Restriction
  on property: in_response_to
  some values from: emotional conditioning
date: 2011-04-04T03:36:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

conditioned place preference behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-04T03:40:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

contextual conditioning behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-04T03:42:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

cued conditioning behavior
type: Class
subclass of: associative learning behavior
date: 2011-04-04T03:43:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

perceptual constancy behavior
type: Class
subclass of: sensation behavior
definition: "Perception of objects remains the same despite changes in their image on the retina." [:http\://science.jrank.org/pages/5094/Perception.html]
date: 2011-04-04T03:47:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

spinal conditioning
type: Class
subclass of: associative learning behavior
date: 2011-04-04T03:48:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

eye blink conditioning behavior
type: Class
equivalent class: Class
  intersection of: classical conditioning
  intersection of: Restriction
    on property: is_about
    some values from: blinking
subclass of: classical conditioning
subclass of: Restriction
  on property: is_about
  some values from: blinking
date: 2011-04-04T03:55:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

jaw movement conditioning behavior
type: Class
equivalent class: Class
  intersection of: classical conditioning
  intersection of: Restriction
    on property: is_about
    some values from: jaw movement
subclass of: classical conditioning
subclass of: Restriction
  on property: is_about
  some values from: jaw movement
date: 2011-04-04T03:57:01Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

vestibular behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: vestibular behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: somatic sensation related behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: vestibular behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the awareness of body balance and movement.
date: 2011-04-04T06:34:21Z
created by: George Gkoutos
has exact synonym: pathological vestibular behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: vestibular behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the awareness of body balance and movement.
source: NBO:GVG

pleasure behavior
type: Class
subclass of: emotional behavior
date: 2011-04-04T07:49:51Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

excitement behavior
type: Class
subclass of: emotional behavior
date: 2011-04-04T07:50:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

distress behavior
type: Class
subclass of: emotional behavior
date: 2011-04-04T07:50:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

motivation behavior
type: Class
subclass of: behavior process
definition: Behavior related to the tendency of an organism to maintain internal equilibrium.
date: 2011-04-04T08:29:40Z
created by: George Gkoutos
has alternative id: NBO:0000050
has exact synonym: behavioral homeostasis
has exact synonym: maintenance behaviour
has exact synonym: perception of need
has OBO namespace: behavior_ontology

Axiom
annotated source: motivation behavior
annotated property: definition
annotated target: Behavior related to the tendency of an organism to maintain internal equilibrium.
source: NBO:GVG

thirst motivation behavior
type: Class
subclass of: response to water deprivation
subclass of: motivation behavior
definition: Behavior related to the deprivation of water.
date: 2011-04-04T08:29:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: thirst motivation behavior
annotated property: definition
annotated target: Behavior related to the deprivation of water.
source: NBO:GVG

hunger motivation behavior
type: Class
subclass of: motivation behavior
definition: Behavior related to the deprivation of food.
date: 2011-04-04T08:30:11Z
created by: George Gkoutos
has exact synonym: appetite related behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: hunger motivation behavior
annotated property: definition
annotated target: Behavior related to the deprivation of food.
source: NBO:GVG

sexual motivation behavior
type: Class
subclass of: motivation behavior
definition: Behavior related to the drive of an organism to engage in sexual activity.
date: 2011-04-04T08:30:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sexual motivation behavior
annotated property: definition
annotated target: Behavior related to the drive of an organism to engage in sexual activity.
source: NBO:GVG

hunger regulation
type: Class
subclass of: hunger motivation behavior
definition: Any process which modulates the physical craving for food.
date: 2011-04-04T08:33:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0032098

Axiom
annotated source: hunger regulation
annotated property: definition
annotated target: Any process which modulates the physical craving for food.
source: NBO:GVG

short term hunger regulation
type: Class
subclass of: hunger regulation
definition: Any process which modulates the physical craving for food over short term food deprivation.
date: 2011-04-04T08:33:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: short term hunger regulation
annotated property: definition
annotated target: Any process which modulates the physical craving for food over short term food deprivation.
source: NBO:GVG

long term hunger regulation
type: Class
subclass of: hunger regulation
definition: Any process which modulates the physical craving for food over long term food deprivation.
date: 2011-04-04T08:33:49Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: long term hunger regulation
annotated property: definition
annotated target: Any process which modulates the physical craving for food over long term food deprivation.
source: NBO:GVG

anorexia nervosa
type: Class
subclass of: eating behavior phenotype
date: 2011-04-04T08:35:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

bulimia nervosa
type: Class
subclass of: eating behavior phenotype
date: 2011-04-04T08:36:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

obesity
type: Class
subclass of: eating behavior phenotype
date: 2011-04-04T08:36:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavioral phenotype
type: Class
definition: An observable characteristic of the behavior of an organism.
date: 2011-04-04T08:51:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000708

Axiom
annotated source: behavioral phenotype
annotated property: definition
annotated target: An observable characteristic of the behavior of an organism.
source: NBO:RH

pathological anxiety
type: Class
subclass of: emotional behavior phenotype
date: 2011-04-04T08:51:52Z
created by: George Gkoutos
has exact synonym: hysteria
has exact synonym: pathological anxiety disorder
has OBO namespace: behavior_ontology

generalized anxiety
type: Class
subclass of: pathological anxiety
definition: "A pathological anxiety characterized by long-lasting anxiety that is not focused on any one object or situation." [wikipedia:Generalized_anxiety_disorder]
date: 2011-04-04T08:52:08Z
created by: George Gkoutos
has exact synonym: GAD
has OBO namespace: behavior_ontology

phobia
type: Class
subclass of: pathological anxiety
definition: A pathological anxiety characterized by fear or anxiety triggered by a specific stimulus or situation.
date: 2011-04-04T08:52:18Z
created by: George Gkoutos
has exact synonym: phobic disorder
has OBO namespace: behavior_ontology

Axiom
annotated source: phobia
annotated property: definition
annotated target: A pathological anxiety characterized by fear or anxiety triggered by a specific stimulus or situation.
source: NBO:GVG

panic
type: Class
subclass of: pathological anxiety
definition: "A pathological anxiety characterized by brief attacks of intense terror and apprehension, often marked by trembling, shaking, confusion, dizziness, nausea, difficulty breathing." [wikipedia:Panic_disorder]
date: 2011-04-04T08:52:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

obsessive-compulsive disorder
type: Class
subclass of: pathological anxiety
definition: "A pathological anxiety primarily characterized by repetitive obsessions (distressing, persistent, and intrusive thoughts or images) and compulsions (urges to perform specific acts or rituals)." [wikipedia:Obsessive%E2%80%93compulsive_disorder]
date: 2011-04-04T08:52:42Z
created by: George Gkoutos
has exact synonym: OCD
has OBO namespace: behavior_ontology
xref: HP:0000722

somatoform behavior phenotype
type: Class
subclass of: behavioral phenotype
definition: "A pathological behavior characterized by one or more symptoms of a physical dysfunction but for which there is no identifiable organic cause." [wikipedia:Somatoform_disorder]
date: 2011-04-04T08:53:04Z
created by: George Gkoutos
has exact synonym: pathological somatoform behaviour
has OBO namespace: behavior_ontology

conversion disorder
type: Class
subclass of: somatoform behavior phenotype
definition: "A somatoform disorder characterised by a physical dysfunction (blindness, deafness, paralysis, numbness, etc. ) that has no underlying organic basis." [wikipedia:Conversion_disorder]
date: 2011-04-04T08:53:18Z
created by: George Gkoutos
has exact synonym: hysteria
has OBO namespace: behavior_ontology

hypochondriasis
type: Class
subclass of: somatoform behavior phenotype
definition: A somatoform disorder characterised by a continuing belief that one has one or more serious illnesses although no medical evidence supports the belief.
date: 2011-04-04T08:53:49Z
created by: George Gkoutos
has exact synonym: health anxiety
has exact synonym: health phobia
has exact synonym: hypochondria
has OBO namespace: behavior_ontology

Axiom
annotated source: hypochondriasis
annotated property: definition
annotated target: A somatoform disorder characterised by a continuing belief that one has one or more serious illnesses although no medical evidence supports the belief.
source: wikipedia:Hypochondriasis

dissociative disorders
type: Class
subclass of: behavioral phenotype
date: 2011-04-04T08:54:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

dissociative amnesia
type: Class
subclass of: dissociative disorders
date: 2011-04-04T08:54:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

dissociative fugue
type: Class
subclass of: dissociative disorders
date: 2011-04-04T08:54:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

dissociative identity disorder
type: Class
subclass of: dissociative disorders
date: 2011-04-04T08:54:45Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

mood disorder
type: Class
subclass of: behavioral phenotype
date: 2011-04-04T08:55:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

major depressive disorder
type: Class
subclass of: depressive disorder
date: 2011-04-04T08:55:36Z
created by: George Gkoutos
has exact synonym: MDD
has exact synonym: clinical depression
has exact synonym: major depression
has exact synonym: unipolar depression
has OBO namespace: behavior_ontology

bipolar disorder
type: Class
subclass of: mood disorder
definition: "A mood disorder formerly characterised by alternating periods of mania and depression (and in some cases rapid cycling, mixed states, and psychotic symptoms)." [wikipedia:Bipolar_disorder]
date: 2011-04-04T08:55:45Z
created by: George Gkoutos
has exact synonym: BD
has exact synonym: bipolar affective disorder
has exact synonym: manic depression
has OBO namespace: behavior_ontology
xref: NBO:0000258

psychotic disorder
type: Class
subclass of: behavioral phenotype
date: 2011-04-04T08:56:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000709

paranoid schizophrenia
type: Class
subclass of: psychotic disorder
date: 2011-04-04T08:56:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

catatonic schizophrenia
type: Class
subclass of: psychotic disorder
date: 2011-04-04T08:57:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

disorganized (hebephrenic) schizophrenia
type: Class
subclass of: psychotic disorder
date: 2011-04-04T08:57:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

undifferentiated schizophrenia
type: Class
subclass of: psychotic disorder
date: 2011-04-04T08:57:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

residual schizophrenia
type: Class
subclass of: psychotic disorder
date: 2011-04-04T08:57:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

personality disorder
type: Class
subclass of: behavioral phenotype
date: 2011-04-04T08:59:01Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000751
comment: (http://www.cliffsnotes.com/study_guide/Classifying-Psychological-Disorders.topicArticleId-25438,articleId-25396.html).

cognitive behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: cognitive behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: PATO_0000001
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: cognitive behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to cognitive processes.
date: 2011-04-04T09:01:18Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cognitive behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to cognitive processes.
source: NBO:RH

delirium
type: Class
subclass of: cognitive behavior phenotype
date: 2011-04-04T09:01:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

dementia
type: Class
subclass of: cognitive behavior phenotype
date: 2011-04-04T09:01:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000726

amnestic disorder
type: Class
subclass of: cognitive behavior phenotype
date: 2011-04-04T09:02:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

feeding behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: feeding behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior associated with the intake of food or liquids.
date: 2011-04-04T09:02:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: feeding behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior associated with the intake of food or liquids.
source: NBO:GVG

group behavior
type: Class
subclass of: social behavior
definition: Behaviors that are described for or done by groups of animals, not individual animals [NBO:SMAC]
date: 2011-04-04T09:05:23Z
created by: George Gkoutos
has exact synonym: group actions
has OBO namespace: behavior_ontology

social facilitation
type: Class
subclass of: group behavior
date: 2011-04-04T09:05:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

social interference
type: Class
subclass of: group behavior
date: 2011-04-04T09:05:52Z
created by: George Gkoutos
has exact synonym: social loafing
has OBO namespace: behavior_ontology

group polarization
type: Class
subclass of: group behavior
date: 2011-04-04T09:06:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

groupthink
type: Class
subclass of: group behavior
date: 2011-04-04T09:06:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

vocal aggression behavior
type: Class
equivalent class: Class
  intersection of: aggressive behavior
  intersection of: Restriction
    on property: by_means
    some values from: vocalization behavior
subclass of: aggressive behavior by means
subclass of: Restriction
  on property: by_means
  some values from: vocalization behavior
definition: A behavioral interaction between organisms in which one organism exhibits aggression using vocal or verbal means.
date: 2011-04-04T09:07:58Z
created by: George Gkoutos
has exact synonym: verbal aggression behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: vocal aggression behavior
annotated property: definition
annotated target: A behavioral interaction between organisms in which one organism exhibits aggression using vocal or verbal means.
source: NBO:GVG

discriminatory behavior
type: Class
subclass of: social behavior
date: 2011-04-04T09:11:04Z
created by: George Gkoutos
has exact synonym: <new synonym>
has exact synonym: discrimination
has exact synonym: prejudice
has OBO namespace: behavior_ontology

gender specific discriminatory behavior
type: Class
subclass of: discriminatory behavior
date: 2011-04-04T09:12:21Z
created by: George Gkoutos
has exact synonym: sexism
has OBO namespace: behavior_ontology

age specific discriminatory behavior
type: Class
subclass of: discriminatory behavior
definition: A discriminatory behavior that is related to age.
date: 2011-04-04T09:12:49Z
created by: George Gkoutos
has exact synonym: ageism
has OBO namespace: behavior_ontology

Axiom
annotated source: age specific discriminatory behavior
annotated property: definition
annotated target: A discriminatory behavior that is related to age.
source: NBO:GVG

attraction-related behavior
type: Class
subclass of: social behavior
date: 2011-04-04T09:16:35Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

affiliation
type: Class
subclass of: attraction-related behavior
definition: Behavior related to having a generally positive attitude toward another person.
date: 2011-04-04T09:16:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: affiliation
annotated property: definition
annotated target: Behavior related to having a generally positive attitude toward another person.
source: MBP:GVG

liking
type: Class
subclass of: attraction-related behavior
definition: Wanting to be with another person.
date: 2011-04-04T09:17:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: liking
annotated property: definition
annotated target: Wanting to be with another person.
source: NBO:GVG

friendship
type: Class
subclass of: liking
date: 2011-04-04T09:17:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

love
type: Class
subclass of: liking
date: 2011-04-04T09:18:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

altruism behavior
type: Class
subclass of: prosocial behavior
definition: A helping behavior (without expectation of extrinsic rewards and sometimes involving personal risk or sacrifice) that benefits individuals or society.
date: 2011-04-04T09:19:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: altruism behavior
annotated property: definition
annotated target: A helping behavior (without expectation of extrinsic rewards and sometimes involving personal risk or sacrifice) that benefits individuals or society.
source: NBO:GVG

prosocial behavior
type: Class
subclass of: social behavior
definition: "Prosocial behavior is caring about the welfare and rights of others, feeling concern and empathy for them, and acting in ways that benefit others." [wikipedia:Prosocial_behavior]
date: 2011-04-04T09:22:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

helping behavior
type: Class
subclass of: prosocial behavior
definition: "Helping behavior refers to voluntary actions intended to help the others, with reward regarded or disregarded." [wikipedia:Helping_behavior]
date: 2011-04-04T09:23:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

reciprocal altruism
type: Class
subclass of: prosocial behavior
definition: "Reciprocal altruism is the idea that the incentive for an individual to help in the present is based on the expectation of the potential receipt in the future." [wikipedia:Helping_behavior]
date: 2011-04-04T09:25:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

social influence related behavior
type: Class
subclass of: social behavior
date: 2011-04-04T09:26:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

conformity
type: Class
subclass of: social influence related behavior
date: 2011-04-04T09:27:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

obedience to authority
type: Class
subclass of: social influence related behavior
date: 2011-04-04T09:27:43Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

bystander intervention
type: Class
subclass of: social influence related behavior
date: 2011-04-04T09:27:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavior stemming from intelligence
type: Class
subclass of: cognitive behavior
definition: Behavior related to one or more capacities of the mind.
date: 2011-04-04T09:30:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavior stemming from intelligence
annotated property: definition
annotated target: Behavior related to one or more capacities of the mind.
source: wikipedia:Intelligence

behavior stemming from emotional intelligence
type: Class
subclass of: behavior stemming from intelligence
definition: "Behavior stemming from the ability to identify, assess, and control the emotions of oneself, of others, and of groups." [wikipedia:Emotional_intelligence]
date: 2011-04-04T09:30:47Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

satiation
type: Class
subclass of: short term hunger regulation
date: 2011-04-18T10:37:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

conciliation behavior
type: Class
subclass of: agonistic behavior
definition: Behavior that facilitates the restoration of normal interactions between parties that recently engaged in a conflict.[NBO:AC]
date: 2011-04-19T09:50:09Z
created by: George Gkoutos
has exact synonym: reconciliation
has exact synonym: reconciliation behavior
has OBO namespace: behavior_ontology

behavior stemming from problem solving
type: Class
subclass of: behavior stemming from intelligence
definition: "Behavior associated with problem finding and problem shaping." [wikipedia:Problem_solving]
date: 2011-04-04T09:31:35Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavior stemming from communication intelligence
type: Class
subclass of: behavior stemming from intelligence
subclass of: communication behavior
definition: Behavior stemming from intelligence associated with the capacity of conveying information. (Example: behavior adaptation in chimpanzees in order to communicate with humans.)
date: 2011-04-04T09:31:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavior stemming from communication intelligence
annotated property: definition
annotated target: Behavior stemming from intelligence associated with the capacity of conveying information. (Example: behavior adaptation in chimpanzees in order to communicate with humans.)
source: NBO:GVG

alloparental behavior
type: Class
subclass of: parental behavior
date: 2011-04-04T09:36:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

male aggressive behavior
type: Class
subclass of: gender-related aggressive behavior
definition: A domineering, assault posture and/or hostile physical action towards animals exhibited by male animals.
date: 2011-04-04T09:39:19Z
created by: George Gkoutos
has exact synonym: male aggressive behaviour
has OBO namespace: behavior_ontology
xref: GO:0001966

Axiom
annotated source: male aggressive behavior
annotated property: definition
annotated target: A domineering, assault posture and/or hostile physical action towards animals exhibited by male animals.
source: NBO:GVG

female aggressive behavior
type: Class
subclass of: gender-related aggressive behavior
definition: A domineering, assault posture and/or hostile physical action towards animals exhibited by female animals.
date: 2011-04-04T09:39:49Z
created by: George Gkoutos
has exact synonym: female aggressive behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: female aggressive behavior
annotated property: definition
annotated target: A domineering, assault posture and/or hostile physical action towards animals exhibited by female animals.
source: NBO:GVG

maternal aggressive behavior
type: Class
subclass of: protection of offspring behavior
subclass of: maternal behavior
subclass of: female aggressive behavior
definition: A domineering, assault posture and/or hostile physical action towards animals exhibited by a mother or attending female.
date: 2011-04-04T09:39:58Z
created by: George Gkoutos
has exact synonym: maternal aggression
has OBO namespace: behavior_ontology
xref: GO:0002125

Axiom
annotated source: maternal aggressive behavior
annotated property: definition
annotated target: A domineering, assault posture and/or hostile physical action towards animals exhibited by a mother or attending female.
source: NBO:GVG

paternal aggressive behavior
type: Class
subclass of: protection of offspring behavior
subclass of: paternal behavior
subclass of: male aggressive behavior
definition: A domineering, assault posture and/or hostile physical action towards animals exhibited by a father or attending male.
date: 2011-04-04T09:40:11Z
created by: George Gkoutos
has exact synonym: paternal aggression
has OBO namespace: behavior_ontology

Axiom
annotated source: paternal aggressive behavior
annotated property: definition
annotated target: A domineering, assault posture and/or hostile physical action towards animals exhibited by a father or attending male.
source: NBO:GVG

memory loss behavior
type: Class
subclass of: memory behavior
definition: Behavior related with the gradual loss of information and experiences stored in the memory of an organism.
date: 2011-04-04T09:49:14Z
created by: George Gkoutos
has exact synonym: forgetting
has OBO namespace: behavior_ontology

Axiom
annotated source: memory loss behavior
annotated property: definition
annotated target: Behavior related with the gradual loss of information and experiences stored in the memory of an organism.
source: NBO:GVG

memory encoding behavior
type: Class
subclass of: memory behavior
date: 2011-04-04T09:49:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

memory storage behavior
type: Class
subclass of: memory behavior
definition: Behavior related with the ability of an organism's ability to store information and experiences.
date: 2011-04-04T09:53:48Z
created by: George Gkoutos
has exact synonym: memory storage behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: memory storage behavior
annotated property: definition
annotated target: Behavior related with the ability of an organism's ability to store information and experiences.
source: NBO:GVG

memory retrieval behavior
type: Class
subclass of: memory behavior
definition: Behavior related with the ability of an organism's ability to recall information and experiences.
date: 2011-04-04T09:55:36Z
created by: George Gkoutos
has exact synonym: memory retrieval behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: memory retrieval behavior
annotated property: definition
annotated target: Behavior related with the ability of an organism's ability to recall information and experiences.
source: NBO:GVG

sensation behavior
type: Class
subclass of: cognitive behavior
definition: Cognitive perception of a sensation by any of the five senses -- vision, touch, smell, taste, and hearing.
date: 2011-04-04T10:00:45Z
created by: George Gkoutos
has alternative id: NBO:0000454
has exact synonym: behavior involving perception
has exact synonym: perception behavior
has OBO namespace: behavior_ontology
comment: Example: moving head to watch passing object.

Axiom
annotated source: sensation behavior
annotated property: definition
annotated target: Cognitive perception of a sensation by any of the five senses -- vision, touch, smell, taste, and hearing.
source: NBO:GVG

social phobia
type: Class
subclass of: phobia
definition: A phobia characterised by fear of social or performance situations in which embarrassment may occur.
date: 2011-04-05T09:35:47Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: social phobia
annotated property: definition
annotated target: A phobia characterised by fear of social or performance situations in which embarrassment may occur.
source: NBO:GVG

acrophobia
type: Class
subclass of: phobia
definition: A phobia characterised by fear of high places.
date: 2011-04-05T09:36:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: acrophobia
annotated property: definition
annotated target: A phobia characterised by fear of high places.
source: NBO:GVG

sleep motivation behavior
type: Class
subclass of: motivation behavior
definition: Behavior related to the actions of an organism in relation to sleep.
date: 2011-04-05T09:46:01Z
created by: George Gkoutos
has exact synonym: sleep motivation behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: sleep motivation behavior
annotated property: definition
annotated target: Behavior related to the actions of an organism in relation to sleep.
source: NBO:GVG

regulation of sleep
type: Class
subclass of: sleep motivation behavior
definition: Any process that modulates the frequency, rate or extent of sleep.
date: 2011-04-05T09:46:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: regulation of sleep
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of sleep.
source: GOC:jl

behavior process
type: Class
subclass of: behavior
definition: "The action, reaction, or performance of an organism in response to external or internal stimuli." [GO:GO\:0007610]
date: 2011-04-05T09:53:10Z
created by: George Gkoutos
has alternative id: NBO:0000000
has exact synonym: behavior
has exact synonym: behaviour
has OBO namespace: behavior_ontology
xref: GO:0007610

visual behavior
type: Class
equivalent class: Class
  intersection of: sensation behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: visual perception
subclass of: sensation behavior
subclass of: Restriction
  on property: in_response_to
  some values from: visual perception
definition: "Behavior related to the actions or reactions of an organism in response to a visual stimulus." [GO:0007632]
date: 2011-04-05T10:36:24Z
created by: George Gkoutos
has exact synonym: behavioral response to visual stimulus
has exact synonym: behavioural response to visual stimulus
has exact synonym: visual behaviour
has OBO namespace: behavior_ontology

optokinetic behavior
type: Class
subclass of: visual behavior
definition: "Behavior related to the actions or reactions of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus." [GO:0007634]
date: 2011-04-05T10:37:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007634

auditory behavior
type: Class
equivalent class: Class
  intersection of: sensation behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of sound
subclass of: sensation behavior
subclass of: Restriction
  on property: by_means
  some values from: UBERON_0002105
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of sound
definition: "Behavior related to the actions or reactions of an organism in response to a sound." [GO:0031223]
date: 2011-04-05T10:38:17Z
created by: George Gkoutos
has exact synonym: hearing behaviour
has OBO namespace: behavior_ontology
xref: GO:0031223

vestibular behavior
type: Class
subclass of: somatic sensation related behavior
definition: Behavior related to the awareness of body balance and movement.
date: 2011-04-05T10:40:36Z
created by: George Gkoutos
has exact synonym: proprioception
has OBO namespace: behavior_ontology

Axiom
annotated source: vestibular behavior
annotated property: definition
annotated target: Behavior related to the awareness of body balance and movement.
source: MBP:GVG

balance
type: Class
subclass of: vestibular behavior
date: 2011-04-05T10:44:05Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

body rotation sensation behavior
type: Class
subclass of: vestibular behavior
date: 2011-04-05T10:44:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

gravitation sensation behavior
type: Class
subclass of: vestibular behavior
subclass of: Restriction
  on property: part of
  some values from: equilibrioception
date: 2011-04-05T10:44:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

movement sensation behavior
type: Class
subclass of: vestibular behavior
date: 2011-04-05T10:44:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

chemosensory behavior
type: Class
equivalent class: Class
  intersection of: behavioral response to chemical stimulus
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of chemical stimulus
subclass of: behavioral response to chemical stimulus
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of chemical stimulus
definition: Behavior as a result of the sensation of chemicals.
date: 2011-04-05T10:48:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0007635

Axiom
annotated source: chemosensory behavior
annotated property: definition
annotated target: Behavior as a result of the sensation of chemicals.
source: NBO:GVG

olfactory behavior
type: Class
equivalent class: Class
  intersection of: chemosensory behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of smell
subclass of: chemosensory behavior
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of smell
definition: Behavior related to the sensation of odors.
date: 2011-04-05T10:48:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042048

Axiom
annotated source: olfactory behavior
annotated property: definition
annotated target: Behavior related to the sensation of odors.
source: NBO:GVG

taste behavior
type: Class
equivalent class: Class
  intersection of: chemosensory behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of taste
subclass of: chemosensory behavior
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of taste
date: 2011-04-05T10:50:50Z
created by: George Gkoutos
has exact synonym: gustatory behavior
has OBO namespace: behavior_ontology
comment: Taste can be described as five basic sensations, sweet, sour, salty, bitter and umamy which can be combined in various ways to make all other taste sensations.

thermosensory behavior
type: Class
equivalent class: Class
  intersection of: cutaneous sensation behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: thermoception
subclass of: cutaneous sensation behavior
subclass of: Restriction
  on property: in_response_to
  some values from: thermoception
definition: Behavior related to environmental temperature.
date: 2011-04-05T11:00:51Z
created by: George Gkoutos
has exact synonym: thermosensation behaviour
has OBO namespace: behavior_ontology
xref: GO:0040040

Axiom
annotated source: thermosensory behavior
annotated property: definition
annotated target: Behavior related to environmental temperature.
source: NBO:GVG

somatic sensation related behavior
type: Class
subclass of: perception behavior by means
definition: Behavior related to the sensations arising from the skin and from the muscles, tendons, and joints.
date: 2011-04-05T11:01:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Sensations arising from the internal organs (the viscera), such as pain or the sense of fullness of the stomach or bladder, may therefore be included, although they are usually considered separately as visceral sensations. Pain arising from the viscera is often felt as though it comes from some part of the body surface or underlying tissue.

Axiom
annotated source: somatic sensation related behavior
annotated property: definition
annotated target: Behavior related to the sensations arising from the skin and from the muscles, tendons, and joints.
source: OBP:GVG

hot sensation behavior
type: Class
equivalent class: Class
  intersection of: thermosensory behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: PATO_0001305
subclass of: thermosensory behavior
subclass of: Restriction
  on property: in_response_to
  some values from: PATO_0001305
definition: Behavior related to the detection of high environmental temperature.
date: 2011-04-05T11:09:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hot sensation behavior
annotated property: definition
annotated target: Behavior related to the detection of high environmental temperature.
source: NBO:GVG

cold sensation behavior
type: Class
equivalent class: Class
  intersection of: thermosensory behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: PATO_0001306
subclass of: thermosensory behavior
subclass of: Restriction
  on property: in_response_to
  some values from: PATO_0001306
definition: Behavior related to the detection of low environmental temperature.
date: 2011-04-05T11:09:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cold sensation behavior
annotated property: definition
annotated target: Behavior related to the detection of low environmental temperature.
source: NBO:GVG

cutaneous sensation behavior
type: Class
subclass of: somatic sensation related behavior
date: 2011-04-05T11:11:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

nociceptive behavior
type: Class
equivalent class: Class
  intersection of: cutaneous sensation behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of pain
subclass of: cutaneous sensation behavior
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of pain
date: 2011-04-05T11:13:27Z
created by: George Gkoutos
has exact synonym: nociception
has exact synonym: pain
has OBO namespace: behavior_ontology

touch related behavior
type: Class
equivalent class: Class
  intersection of: cutaneous sensation behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: sensory perception of touch
subclass of: cutaneous sensation behavior
subclass of: Restriction
  on property: in_response_to
  some values from: sensory perception of touch
date: 2011-04-05T11:36:23Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

chemical nociceptive behavior
type: Class
equivalent class: Class
  intersection of: nociceptive behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: detection of chemical stimulus involved in sensory perception of pain
subclass of: nociceptive behavior
subclass of: Restriction
  on property: in_response_to
  some values from: detection of chemical stimulus involved in sensory perception of pain
date: 2011-04-05T12:38:39Z
created by: George Gkoutos
has exact synonym: chemical nociception behaviour
has OBO namespace: behavior_ontology

mechanical nociceptive behavior
type: Class
equivalent class: Class
  intersection of: nociceptive behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: detection of mechanical stimulus involved in sensory perception of pain
subclass of: nociceptive behavior
subclass of: Restriction
  on property: in_response_to
  some values from: detection of mechanical stimulus involved in sensory perception of pain
date: 2011-04-05T12:39:46Z
created by: George Gkoutos
has exact synonym: mechanical nociception behaviour
has OBO namespace: behavior_ontology

thermal nociceptive behavior
type: Class
equivalent class: Class
  intersection of: nociceptive behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: detection of temperature stimulus involved in sensory perception of pain
subclass of: nociceptive behavior
subclass of: Restriction
  on property: in_response_to
  some values from: detection of temperature stimulus involved in sensory perception of pain
date: 2011-04-05T12:41:15Z
created by: George Gkoutos
has exact synonym: thermal nociception behaviour
has OBO namespace: behavior_ontology

chemically-elicited antinociceptive behavior
type: Class
subclass of: nociceptive behavior
date: 2011-04-05T12:45:31Z
created by: George Gkoutos
has exact synonym: chemically-elicited antinociception behaviour
has OBO namespace: behavior_ontology

pressure related behavior
type: Class
subclass of: cutaneous sensation behavior
date: 2011-04-05T02:06:22Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

kinesthetic behavior
type: Class
subclass of: behavior process
definition: "Movement behavior of the body or its parts."
date: 2011-04-05T02:08:47Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

motor coordination
type: Class
subclass of: vestibular behavior
definition: "The coordination of combinations of body movements created with the kinematic (such as spatial direction) and kinetic (force) parameters that result in intended actions." [wikipedia:Motor_coordination]
date: 2011-04-05T03:32:44Z
created by: George Gkoutos
has alternative id: NBO:0000340
has OBO namespace: behavior_ontology

eye-hand coordination
type: Class
subclass of: fine motor coordination
definition: "The coordinated control of eye movement with hand movement, and the processing of visual input to guide reaching and grasping along with the use of proprioception of the hands to guide the eyes." [wikipedia:Eye%E2%80%93hand_coordination]
date: 2011-04-05T03:43:28Z
created by: George Gkoutos
has exact synonym: hand eye coordination
has OBO namespace: behavior_ontology
comment: Optic apraxia - total inability of a person to coordinate eye and hand movements.\nOptic ataxia - inability of a person to coordinate eye and hand movements.

limb coordination
type: Class
subclass of: gross motor coordination
definition: The coordination of limb movement.
date: 2011-04-05T03:49:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: limb coordination
annotated property: definition
annotated target: The coordination of limb movement.
source: NBO:GVG

intralimb coordination
type: Class
subclass of: upper limb coordination
definition: Coordination that results in spatial and temporal planning of reaching and grasping.
date: 2011-04-05T03:57:56Z
created by: George Gkoutos
has exact synonym: intra-limb coordination
has OBO namespace: behavior_ontology

Axiom
annotated source: intralimb coordination
annotated property: definition
annotated target: Coordination that results in spatial and temporal planning of reaching and grasping.
source: NBO:GVG

interlimb coordination
type: Class
subclass of: upper limb coordination
definition: Coordination that results in bimanual synchronization and temporal association of the hands.
date: 2011-04-05T03:58:29Z
created by: George Gkoutos
has exact synonym: inter-limb coordination
has OBO namespace: behavior_ontology

Axiom
annotated source: interlimb coordination
annotated property: definition
annotated target: Coordination that results in bimanual synchronization and temporal association of the hands.
source: NBO:GVG

lower limb coordination
type: Class
subclass of: limb coordination
definition: The coordination of lower limb movement.
date: 2011-04-05T04:05:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: lower limb coordination
annotated property: definition
annotated target: The coordination of lower limb movement.
source: NBO:GVG

upper limb coordination
type: Class
subclass of: limb coordination
definition: The coordination of upper limb movement.
date: 2011-04-05T04:05:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: upper limb coordination
annotated property: definition
annotated target: The coordination of upper limb movement.
source: NBO:GVG

gross motor coordination
type: Class
subclass of: motor coordination
definition: The coordination of large muscle groups and whole body movement.
date: 2011-04-05T04:10:52Z
created by: George Gkoutos
has exact synonym: large muscle coordination
has exact synonym: whole body coordination
has OBO namespace: behavior_ontology

Axiom
annotated source: gross motor coordination
annotated property: definition
annotated target: The coordination of large muscle groups and whole body movement.
source: NBO:GVG

fine motor coordination
type: Class
subclass of: motor coordination
definition: Coordination of small muscle movements which occur usually in coordination with the eye.
date: 2011-04-05T04:14:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: fine motor coordination
annotated property: definition
annotated target: Coordination of small muscle movements which occur usually in coordination with the eye.
source: NBO:GVG

manual dexterity
type: Class
subclass of: fine motor coordination
date: 2011-04-05T04:17:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

graphomotor coordination
type: Class
subclass of: motor coordination
definition: Coordination involved in writing.
date: 2011-04-05T04:19:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: graphomotor coordination
annotated property: definition
annotated target: Coordination involved in writing.
source: NBO:GVG

body coordination
type: Class
subclass of: gross motor coordination
definition: The coordination of the whole body movement.
date: 2011-04-05T05:28:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: body coordination
annotated property: definition
annotated target: The coordination of the whole body movement.
source: NBO:GVG

upper body coordination
type: Class
subclass of: body coordination
definition: The coordination of the lower body movement.
date: 2011-04-05T05:30:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: upper body coordination
annotated property: definition
annotated target: The coordination of the lower body movement.
source: NBO:GVG

lower body coordination
type: Class
subclass of: body coordination
definition: The coordination of the upper body movement.
date: 2011-04-05T05:30:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: lower body coordination
annotated property: definition
annotated target: The coordination of the upper body movement.
source: NBO:GVG

bilateral coordination
type: Class
subclass of: gross motor coordination
date: 2011-04-05T05:33:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

posture
type: Class
subclass of: vestibular behavior
definition: Intentionally or habitually assumed arrangement of the body and its limbs.
date: 2011-04-06T09:30:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: posture
annotated property: definition
annotated target: Intentionally or habitually assumed arrangement of the body and its limbs.
source: NBO:GVG

body posture
type: Class
equivalent class: Class
  intersection of: posture
  intersection of: Restriction
    on property: has_participant
    some values from: UBERON_0000309
subclass of: posture
subclass of: Restriction
  on property: has_participant
  some values from: UBERON_0000309
definition: Intentionally or habitually assumed arrangement of the body.
date: 2011-04-06T09:30:45Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: body posture
annotated property: definition
annotated target: Intentionally or habitually assumed arrangement of the body.
source: NBO:GVG

limb posture
type: Class
equivalent class: Class
  intersection of: posture
  intersection of: Restriction
    on property: has_participant
    some values from: UBERON_0002101
subclass of: posture
subclass of: Restriction
  on property: has_participant
  some values from: UBERON_0002101
definition: Intentionally or habitually assumed arrangement of the limbs.
date: 2011-04-06T09:31:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: limb posture
annotated property: definition
annotated target: Intentionally or habitually assumed arrangement of the limbs.
source: NBO:GVG

resting posture
type: Class
subclass of: posture
definition: Intentionally or habitually assumed arrangement of the body and its limbs in inactivity.
date: 2011-04-06T09:31:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: resting posture
annotated property: definition
annotated target: Intentionally or habitually assumed arrangement of the body and its limbs in inactivity.
source: NBO:GVG

terrestrial locomotory behavior
type: Class
subclass of: locomotory behavior
definition: Behavior associated with surface locomotion.
date: 2011-04-06T09:44:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: terrestrial locomotory behavior
annotated property: definition
annotated target: Behavior associated with surface locomotion.
source: NBO:GVG

leaping behavior
type: Class
subclass of: aerial locomotion behavior
definition: Behavior related to the upward thrust produced by the rapid, simultaneous extension of the hind legs with the intend to cross wide gaps in the locomotor surface.
date: 2011-04-06T09:47:57Z
created by: George Gkoutos
has exact synonym: saltation
has OBO namespace: behavior_ontology

Axiom
annotated source: leaping behavior
annotated property: definition
annotated target: Behavior related to the upward thrust produced by the rapid, simultaneous extension of the hind legs with the intend to cross wide gaps in the locomotor surface.
source: MBP:GVG

gait
type: Class
subclass of: limb coordination
definition: "The pattern of movement of the limbs of animals, characterized by elements of progression, stability, speed and length over the ground." [MP:0001406]
date: 2011-04-06T10:07:23Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

stride
type: Class
subclass of: gait
definition: A behavioral pattern characterized by the distance covered by as many steps as there are legs.
date: 2011-04-06T10:08:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: stride
annotated property: definition
annotated target: A behavioral pattern characterized by the distance covered by as many steps as there are legs.
source: NBO:GVG

crawling behavior
type: Class
subclass of: terrestrial locomotory behavior
definition: Behavior related to the movement resulting by dragging the body close to the ground.
date: 2011-04-06T11:39:16Z
created by: George Gkoutos
has exact synonym: crawl
has OBO namespace: behavior_ontology

Axiom
annotated source: crawling behavior
annotated property: definition
annotated target: Behavior related to the movement resulting by dragging the body close to the ground.
source: NBO:GVG

arboreal locomotion behavior
type: Class
subclass of: climbing behavior
definition: "Behavior related to the locomotion of animals in trees." [wikipedia:Arboreal_locomotion]
date: 2011-04-06T11:40:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

brachiation
type: Class
subclass of: arboreal locomotion behavior
definition: arm over arm swinging movement through arboreal environment [NBO:AC]
date: 2011-04-06T11:42:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Arguably the epitome of arboreal locomotion, it involves swinging with the arms from one handhold to another.

aerial locomotion behavior
type: Class
subclass of: locomotory behavior
definition: Behavior related to the movement of an organism from one location to another through the air.
date: 2011-04-06T11:44:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: aerial locomotion behavior
annotated property: definition
annotated target: Behavior related to the movement of an organism from one location to another through the air.
source: NBO:GVG

flight behavior
type: Class
subclass of: aerial locomotion behavior
definition: Behavior related to the self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
date: 2011-04-06T11:45:51Z
created by: George Gkoutos
has alternative id: NBO:0000072
has exact synonym: fly
has exact synonym: flying
has OBO namespace: behavior_ontology
xref: GO:0007629

Axiom
annotated source: flight behavior
annotated property: definition
annotated target: Behavior related to the self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
source: NBO:GVG

climbing behavior
type: Class
subclass of: locomotory behavior
definition: Behavior related to the ascending a steep object.
date: 2011-04-06T11:46:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: climbing behavior
annotated property: definition
annotated target: Behavior related to the ascending a steep object.
source: NBO:GVG

gliding behavior
type: Class
subclass of: aerial locomotion behavior
definition: Behavior related to the expansion lateral surface of the body with the intention of increasing the wind resistance against the body and hence reducing the speed of falling.
date: 2011-04-06T12:20:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: gliding behavior
annotated property: definition
annotated target: Behavior related to the expansion lateral surface of the body with the intention of increasing the wind resistance against the body and hence reducing the speed of falling.
source: NBO:GVG

saltation
type: Class
subclass of: jumping behavior
definition: Behavior related to the upward thrust produced by the rapid, simultaneous extension of the hind legs with the intend to rise in the air.
date: 2011-04-06T12:25:30Z
created by: George Gkoutos
has exact synonym: hopping
has OBO namespace: behavior_ontology

Axiom
annotated source: saltation
annotated property: definition
annotated target: Behavior related to the upward thrust produced by the rapid, simultaneous extension of the hind legs with the intend to rise in the air.
source: NBO:GVG

aquatic locomotion
type: Class
subclass of: locomotory behavior
definition: Behavior related to the movement of an organism from one location to another through a liquid medium.
date: 2011-04-06T12:33:07Z
created by: George Gkoutos
has exact synonym: swim
has exact synonym: swimming
has OBO namespace: behavior_ontology

Axiom
annotated source: aquatic locomotion
annotated property: definition
annotated target: Behavior related to the movement of an organism from one location to another through a liquid medium.
source: NBO:GVG

directional control of locomotion
type: Class
subclass of: locomotory behavior
definition: Behavior related to the control of the direction of locomotion.
date: 2011-04-06T01:15:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: directional control of locomotion
annotated property: definition
annotated target: Behavior related to the control of the direction of locomotion.
source: NBO:GVG

locomotory orientation behavior
type: Class
subclass of: directional control of locomotion
definition: Behavior related to the ability of an animal to determine and to alter its position in the environment.
date: 2011-04-06T01:16:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: locomotory orientation behavior
annotated property: definition
annotated target: Behavior related to the ability of an animal to determine and to alter its position in the environment.
source: NBO:GVG

kinesis
type: Class
subclass of: locomotory orientation behavior
definition: Alteration of speed or direction of movement in response to a sensory stimulus.
date: 2011-04-06T01:17:18Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042465

Axiom
annotated source: kinesis
annotated property: definition
annotated target: Alteration of speed or direction of movement in response to a sensory stimulus.
source: NBO:GVG

taxis
type: Class
subclass of: locomotory orientation behavior
definition: Locomotory orientation in a specific spatial relationship to a stimulus.
date: 2011-04-06T01:17:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0042330

Axiom
annotated source: taxis
annotated property: definition
annotated target: Locomotory orientation in a specific spatial relationship to a stimulus.
source: NBO:GVG

steering behavior
type: Class
subclass of: directional control of locomotion
definition: Behavior related to the mechanical alteration of the locomotor pattern through which the animal adjusts its position.
date: 2011-04-06T01:18:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: steering behavior
annotated property: definition
annotated target: Behavior related to the mechanical alteration of the locomotor pattern through which the animal adjusts its position.
source: NBO:GVG

chemotactic behavior
type: Class
subclass of: taxis
definition: "Locomotory orientation in response to specific chemical concentration gradient." [GO:0006935]
date: 2011-04-06T01:23:34Z
created by: George Gkoutos
has exact synonym: chemotaxis
has OBO namespace: behavior_ontology
xref: GO:0006935

gravitactic behavior
type: Class
subclass of: taxis
definition: "Locomotory orientation in response to gravity." [GO:0048062]
date: 2011-04-06T01:27:22Z
created by: George Gkoutos
has exact synonym: geotactic behaviour
has exact synonym: gravitaxis
has OBO namespace: behavior_ontology
xref: GO:0042332

negative gravitactic behavior
type: Class
subclass of: gravitactic behavior
definition: "Locomotory orientation away from the source of gravity." [GO:0048060]
date: 2011-04-06T01:32:49Z
created by: George Gkoutos
has exact synonym: negative geotactic behaviour
has exact synonym: negative gravitaxis
has OBO namespace: behavior_ontology
xref: GO:0048060

positive gravitactic behavior
type: Class
subclass of: gravitactic behavior
definition: "Locomotory orientation towards the source of gravity." [GO:0048061]
date: 2011-04-06T01:34:24Z
created by: George Gkoutos
has exact synonym: positive geotactic behaviour
has exact synonym: positive gravitaxis
has OBO namespace: behavior_ontology
xref: GO:0048061

thigmotaxis
type: Class
subclass of: mechanical stimulus taxis
definition: "Locomotory orientation in response to touch." [GO:0001966]
date: 2011-04-06T01:45:18Z
created by: George Gkoutos
has exact synonym: stereotaxis
has OBO namespace: behavior_ontology

energy taxis
type: Class
subclass of: taxis
definition: "Locomotory orientation in response to physical parameters involved in energy generation." [GO:0009453]
date: 2011-04-06T01:47:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0009453

phototactic behavior
type: Class
subclass of: energy taxis
definition: "Locomotory orientation in response to light." [GO:0042331]
date: 2011-04-06T01:48:33Z
created by: George Gkoutos
has exact synonym: phototaxis
has OBO namespace: behavior_ontology
xref: GO:0042331

thermotaxis
type: Class
subclass of: energy taxis
definition: "Locomotory orientation in response to a temperature gradient." [GO:0043052]
date: 2011-04-06T01:50:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0043052

phonotaxis
type: Class
subclass of: mechanical stimulus taxis
definition: Locomotory orientation in response to sound.
date: 2011-04-06T01:58:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: phonotaxis
annotated property: definition
annotated target: Locomotory orientation in response to sound.
source: NBO:GVG

mechanical stimulus taxis
type: Class
subclass of: taxis
definition: Locomotory orientation in response to mechanical stimulus.
date: 2011-04-06T01:59:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: mechanical stimulus taxis
annotated property: definition
annotated target: Locomotory orientation in response to mechanical stimulus.
source: NBO:GVG

barotaxis
type: Class
subclass of: mechanical stimulus taxis
definition: Locomotory orientation in response to pressure.
date: 2011-04-06T02:01:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: barotaxis
annotated property: definition
annotated target: Locomotory orientation in response to pressure.
source: NBO:GVG

involuntary movement behavior
type: Class
subclass of: body part movement
disjoint with: voluntary movement behavior
definition: Behavior related to movements that occur independent of planning.
date: 2011-04-06T02:35:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Movevents listed here are involuntary, but may be also generated by free will, like blinking of the eyelids and respiratory movements.

Axiom
annotated source: involuntary movement behavior
annotated property: definition
annotated target: Behavior related to movements that occur independent of planning.
source: NBO:GVG

reflexive behavior
type: Class
equivalent class: Class
  intersection of: involuntary movement behavior
  intersection of: Restriction
    on property: by_means
    some values from: reflex
subclass of: involuntary movement behavior
subclass of: Restriction
  on property: by_means
  some values from: reflex
definition: Behavior related to involuntary movement in response to a stimulus.
date: 2011-04-06T02:36:55Z
created by: George Gkoutos
has alternative id: NBO:0000004
has exact synonym: reflex behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: reflexive behavior
annotated property: definition
annotated target: Behavior related to involuntary movement in response to a stimulus.
source: NBO:GVG

primitive reflex
type: Class
subclass of: reflexive behavior
definition: "Reflex actions originating in the central nervous system that are exhibited by normal infants in response to particular stimuli." [wikipedia:Primitive_reflexes]
date: 2011-04-06T02:44:15Z
created by: George Gkoutos
has exact synonym: infant reflex
has exact synonym: infantile reflex
has exact synonym: newborn reflex
has OBO namespace: behavior_ontology

startle reflex
type: Class
subclass of: reflexive behavior
definition: "An action or movement due to the application of a sudden unexpected stimulus." [wikipedia:Startle_reflex]
date: 2011-04-06T02:55:21Z
created by: George Gkoutos
has exact synonym: alarm reaction
has OBO namespace: behavior_ontology

tonic labyrinthine reflex
type: Class
subclass of: primitive reflex
definition: "A reflex that arises when tilting the head back while lying on the back causes the back to stiffen and even arch backwards, the legs to straighten, stiffen, and push together, the toes to point, the arms to bend at the elbows and wrists, and the hands to become fisted or the fingers to curl." [wikipedia:Tonic_labyrinthine_reflex]
date: 2011-04-06T03:03:51Z
created by: George Gkoutos
has exact synonym: TLR
has OBO namespace: behavior_ontology

asymmetrical tonic neck reflex
type: Class
subclass of: primitive reflex
definition: "A reflex that assists in the birthing process and helps to develop muscle tone, kicking and stimulates vestibular function in utero." [wikipedia:Asymmetrical_tonic_neck_reflex]
date: 2011-04-06T03:05:52Z
created by: George Gkoutos
has exact synonym: ATNR
has exact synonym: fencing reflex
has OBO namespace: behavior_ontology

symmetrical tonic neck reflex
type: Class
subclass of: primitive reflex
definition: A reflex that causes the eyes to alternately fixate at far and near, expanding vision development from arms length to far away.
date: 2011-04-06T03:10:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: symmetrical tonic neck reflex
annotated property: definition
annotated target: A reflex that causes the eyes to alternately fixate at far and near, expanding vision development from arms length to far away.
source: MBP:GVG

galant reflex
type: Class
subclass of: primitive reflex
definition: "It is elicited by holding the newborn in ventral suspension (face down) and stroking along the one side of the spine. A reflex that caused the laterally flex toward the stimulated side when a newborn is held in ventral suspension (face down) and stroking along the one side of the spine." [NBO:Galant_reflex]
date: 2011-04-06T03:11:13Z
created by: George Gkoutos
has exact synonym: spinal galant
has OBO namespace: behavior_ontology

babkin reflex
type: Class
subclass of: primitive reflex
definition: "A reflex elicited by the application of pressure to both palms resulting varying responses such as head flexion, head rotation or opening of the mouth, or a combination of these responses." [wikipedia:Primitive_reflexes]
date: 2011-04-06T03:14:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

swimming reflex
type: Class
subclass of: primitive reflex
definition: "A reflex that causes the infant to begin to paddle and kick in a swimming motion upon its placement face down in a pool of water." [NBO:Primitive_reflexes]
date: 2011-04-06T03:15:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

plantar reflex
type: Class
subclass of: primitive reflex
subclass of: stretch reflex
definition: "A reflex elicited when the sole of the foot is stimulated with a blunt instrument." [wikipedia:Plantar_reflex]
date: 2011-04-06T03:18:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

palmar grasp reflex
type: Class
subclass of: primitive reflex
definition: "A reflex elicited by the placement of an object in the infant's hand and strokes their palm, causing its fingers to close and grasp it." [wikipedia:Primitive_reflexes]
date: 2011-04-06T03:20:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

rooting reflex
type: Class
subclass of: primitive reflex
definition: "A reflex that causes a newborn infant to turn his head toward anything that strokes his cheek or mouth, searching for the object by moving his head in steadily decreasing arcs until the object is found." [wikipedia:Primitive_reflexes]
date: 2011-04-06T03:22:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

sucking reflex
type: Class
subclass of: suckling behavior
subclass of: primitive reflex
definition: "A reflex that causes the infant to instinctively suck at anything that touches the roof of their mouth and suddenly starts to suck simulating the way they naturally eat." [wikipedia:Primitive_reflexes]
date: 2011-04-06T03:25:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

walking reflex
type: Class
subclass of: primitive reflex
definition: "A reflex that causes the infant to attempt to 'walk' by placing one foot in front of the other when the soles of their feet touch a flat surface." [wikipedia:Primitive_reflexes]
date: 2011-04-06T03:26:47Z
created by: George Gkoutos
has exact synonym: stepping reflex
has OBO namespace: behavior_ontology

voluntary movement behavior
type: Class
subclass of: voluntary musculoskeletal movement
subclass of: body part movement
definition: Behavior related to movements executed with intent.
date: 2011-04-06T03:32:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: voluntary movement behavior
annotated property: definition
annotated target: Behavior related to movements executed with intent.
source: NBO:GVG

stretch reflex
type: Class
subclass of: reflexive behavior
definition: "A muscle contraction in response to stretching within the muscle." [wikipedia:Stretch_reflex]
date: 2011-04-06T04:02:17Z
created by: George Gkoutos
has exact synonym: deep tendon reflex
has OBO namespace: behavior_ontology

biceps reflex
type: Class
subclass of: stretch reflex
definition: A deep tendon reflex that elicits involuntary contraction of the biceps brachii muscle.
date: 2011-04-06T04:06:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: biceps reflex
annotated property: definition
annotated target: A deep tendon reflex that elicits involuntary contraction of the biceps brachii muscle.
source: NBO:GVG

brachioradialis reflex
type: Class
subclass of: stretch reflex
definition: "A deep tendon reflex elicited by striking the lateral surface of the forearm proximal to the distal head of the radius, characterized by normal slight elbow flexion and forearm supination." [Medical disctionary:http\://medical-dictionary.thefreedictionary.com/brachioradialis+reflex]
date: 2011-04-06T04:07:37Z
created by: George Gkoutos
has exact synonym: supinator reflex
has OBO namespace: behavior_ontology

extensor digitorum reflex
type: Class
subclass of: stretch reflex
definition: A reflex that elicits involuntary contraction of the extensor digitorum muscle.
date: 2011-04-06T04:09:37Z
created by: George Gkoutos
has exact synonym: BER
has exact synonym: Braunecker-Effenberg reflex
has OBO namespace: behavior_ontology

Axiom
annotated source: extensor digitorum reflex
annotated property: definition
annotated target: A reflex that elicits involuntary contraction of the extensor digitorum muscle.
source: NBO:GVG

triceps reflex
type: Class
subclass of: stretch reflex
definition: "A deep tendon reflex that elicits involuntary contraction of the triceps brachii muscle." [wikipedia:Triceps_reflex]
date: 2011-04-06T04:12:22Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

patellar reflex
type: Class
subclass of: stretch reflex
definition: A deep tendon reflex that elicits extension of the leg resulting from a sharp tap on the patellar tendon.
date: 2011-04-06T04:18:23Z
created by: George Gkoutos
has exact synonym: knee-jerk reflex
has OBO namespace: behavior_ontology

Axiom
annotated source: patellar reflex
annotated property: definition
annotated target: A deep tendon reflex that elicits extension of the leg resulting from a sharp tap on the patellar tendon.
source: NBO:GVG

ankle jerk reflex
type: Class
subclass of: stretch reflex
definition: "A reflex bending of the foot resulting from contraction of the calf muscles when the Achilles tendon is sharply struck." [Medical Dictionary:http\://medical-dictionary.thefreedictionary.com/Achilles+reflex]
date: 2011-04-06T04:20:42Z
created by: George Gkoutos
has exact synonym: Achilles reflex
has exact synonym: Achilles tendon reflex
has exact synonym: ankle reflex
has exact synonym: triceps surae reflex
has OBO namespace: behavior_ontology

cranial nerve related reflex
type: Class
subclass of: reflexive behavior
definition: A reflex that involves cranial nerves.
date: 2011-04-06T04:28:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cranial nerve related reflex
annotated property: definition
annotated target: A reflex that involves cranial nerves.
source: wikipedia:Reflex

pupillary light reflex
type: Class
subclass of: cranial nerve related reflex
definition: "A reflex that controls the diameter of the pupil, in response to the intensity (luminance) of light that falls on the retina of the eye, thereby assisting in adaptation to various levels of darkness and light, in addition to retinal sensitivity." [wikipedia:Pupillary_light_reflex]
date: 2011-04-06T04:28:58Z
created by: George Gkoutos
has exact synonym: pupillary reflex
has OBO namespace: behavior_ontology

accommodation reflex
type: Class
subclass of: cranial nerve related reflex
definition: "A reflex action of the eye, in response to focusing on a near object, then looking at distant object (and vice versa), comprising coordinated changes in vergence, lens shape and pupil size." [wikipedia:Accommodation_reflex]
date: 2011-04-06T04:29:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

jaw jerk reflex
type: Class
subclass of: cranial nerve related reflex
date: 2011-04-06T04:30:58Z
created by: George Gkoutos
has exact synonym: masseter reflex
has OBO namespace: behavior_ontology

corneal reflex
type: Class
subclass of: cranial nerve related reflex
definition: "An involuntary blinking of the eyelids elicited by stimulation of the cornea." [wikipedia:Corneal_reflex]
date: 2011-04-06T06:08:06Z
created by: George Gkoutos
has db xref: GO:0060082
has exact synonym: blink reflex
has exact synonym: blinking
has OBO namespace: behavior_ontology

Axiom
annotated source: corneal reflex
annotated property: hasDbXref
annotated target: GO:0060082
contributor: http://orcid.org/0000-0002-4277-2151

vestibulo-ocular reflex
type: Class
subclass of: cranial nerve related reflex
definition: "A reflex eye movement that stabilizes images on the retina during head movement by producing an eye movement in the direction opposite to head movement, thus preserving the image on the center of the visual field." [wikipedia:Vestibulo-ocular_reflex]
date: 2011-04-06T06:11:09Z
created by: George Gkoutos
has exact synonym: VOR
has exact synonym: oculovestibular reflex
has exact synonym: vestibuloocular reflex
has OBO namespace: behavior_ontology

physiologic nystagmus
type: Class
subclass of: vestibulo-ocular reflex
definition: "A form of involuntary eye movement that is part of the vestibulo-ocular reflex (VOR). It is characterized by alternating smooth pursuit in one direction and saccadic movement in the other direction." [wikipedia:Physiologic_nystagmus]
date: 2011-04-06T06:16:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

pharyngeal reflex
type: Class
subclass of: cranial nerve related reflex
definition: "A reflex contraction of the back of the throat, evoked by touching the soft palate." [wikipedia:Gag_reflex]
date: 2011-04-06T06:17:32Z
created by: George Gkoutos
has exact synonym: gag reflex
has exact synonym: swallowing reflex
has OBO namespace: behavior_ontology

sleeping behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sleeping behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: rhythmic behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sleeping behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
date: 2011-04-07T01:19:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sleeping behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
source: NBO:GVG

bruxism
type: Class
subclass of: NREM parasomnia
definition: A NREM parasomnia characterised by Involuntarily grinding of teeth while sleeping.
date: 2011-04-07T01:20:00Z
created by: George Gkoutos
has exact synonym: <new synonym>
has exact synonym: teeth grinding
has OBO namespace: behavior_ontology
xref: HP:0003763

Axiom
annotated source: bruxism
annotated property: definition
annotated target: A NREM parasomnia characterised by Involuntarily grinding of teeth while sleeping.
source: MBP:GVG

delayed sleep phase syndrome
type: Class
subclass of: intrinsic circadian rhythm sleep disorder
definition: "A circadian rhythm sleep disorder characterized by a much later than normal timing of sleep onset and offset and a period of peak alertness in the middle of the night." [wikipedia:Delayed_sleep_phase_syndrome]
date: 2011-04-07T01:22:32Z
created by: George Gkoutos
has exact synonym: DSPS
has exact synonym: delayed sleep-phase disorder (DSPD)
has exact synonym: delayed sleep-phase type (DSPT)
has OBO namespace: behavior_ontology

insomnia
type: Class
subclass of: dyssomnia
definition: Inability to fall asleep and/or remain asleep for a reasonable amount of time.
date: 2011-04-07T01:23:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: insomnia
annotated property: definition
annotated target: Inability to fall asleep and/or remain asleep for a reasonable amount of time.
source: NBO:GVG

narcolepsy
type: Class
subclass of: intrinsic sleep disorder
definition: A dyssomnia characterised by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times.
date: 2011-04-07T01:24:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0005279

Axiom
annotated source: narcolepsy
annotated property: definition
annotated target: A dyssomnia characterised by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times.
source: wikipedia:Narcolepsy

sleep terror
type: Class
subclass of: NREM parasomnia
definition: A NREM parasomnia characterised by abrupt awakening from sleep with behavior consistent with terror and a temporary inability to regain full consciousness.
date: 2011-04-07T01:25:22Z
created by: George Gkoutos
has exact synonym: Pavor nocturnus
has exact synonym: night terror
has OBO namespace: behavior_ontology

Axiom
annotated source: sleep terror
annotated property: definition
annotated target: A NREM parasomnia characterised by abrupt awakening from sleep with behavior consistent with terror and a temporary inability to regain full consciousness.
source: NBO:GVG

abdominal reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex that results in the contraction of the muscles of the abdominal wall in response to stimulation of the overlying skin." [web:http\://www.merriam-webster.com/medical/abdominal%20reflex]
date: 2011-04-07T05:12:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

anocutaneous reflex
type: Class
subclass of: reflexive behavior
definition: "Reflexive contraction of the external anal sphincter upon stroking of the skin around the anus." [wikipedia:Anal_wink]
date: 2011-04-07T05:12:40Z
created by: George Gkoutos
has exact synonym: anal reflex
has exact synonym: anal wink
has exact synonym: perineal reflex
has OBO namespace: behavior_ontology

cremasteric reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex is elicited by lightly stroking the superior and medial (inner) part of the thigh resulting in a contraction of the cremaster muscle that pulls up the scrotum and testis on the side stroked." [wikipedia:Cremasteric_reflex]
date: 2011-04-07T05:15:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

mammalian diving reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex in mammals which optimises respiration to allow staying underwater for extended periods of time." [wikipedia:Mammalian_diving_reflex]
date: 2011-04-07T05:16:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

visceromotor reflex
type: Class
subclass of: abdominal reflex
definition: "An increase in tonus (normal tension) of the tissues of the abdominal muscles resulting from painful stimuli originating in a viscus." [:http\://www.wordinfo.info/words/index/inf]
date: 2011-04-07T05:18:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

muscular defense
type: Class
subclass of: visceromotor reflex
definition: "A reflex of the abdominal muscles to contract upon mechanical force to the abdomen, and serves as protection." [wikipedia:Muscular_defense]
date: 2011-04-07T05:20:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

scratch reflex
type: Class
subclass of: scratching
subclass of: reflexive behavior
definition: "A response to activation of sensory neurons whose peripheral terminals are located on the surface of the body." [wikipedia:Scratch_reflex]
date: 2011-04-07T05:21:15Z
created by: George Gkoutos
has alternative id: NBO:0000021
has exact synonym: self-scratching
has OBO namespace: behavior_ontology

acoustic startle reflex
type: Class
subclass of: startle reflex
definition: An action or movement due to the application of a sudden unexpected loud noise.
date: 2011-04-07T05:31:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: acoustic startle reflex
annotated property: definition
annotated target: An action or movement due to the application of a sudden unexpected loud noise.
source: NBO:GVG

withdrawal reflex
type: Class
subclass of: stretch reflex
definition: A reflex where the body reacts to pain or unpleasant stimuli by trying to move itself away from the source.
date: 2011-04-07T05:35:05Z
created by: George Gkoutos
has exact synonym: flexor withdrawal reflex
has exact synonym: nociceptive reflex
has OBO namespace: behavior_ontology

Axiom
annotated source: withdrawal reflex
annotated property: definition
annotated target: A reflex where the body reacts to pain or unpleasant stimuli by trying to move itself away from the source.
source: NBO:GVG

crossed extensor reflex
type: Class
subclass of: withdrawal reflex
definition: "A reflex where the flexors in the withdrawing limb contract and the extensors relax, while in the other limb, the opposite occurs." [wikipedia:Crossed_extensor_reflex]
date: 2011-04-07T05:39:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

acoustic reflex
type: Class
subclass of: reflexive behavior
definition: "An involuntary muscle contraction that occurs in the middle ear of mammals in response to high-intensity sound stimuli." [wikipedia:Acoustic_reflex]
date: 2011-04-07T05:41:07Z
created by: George Gkoutos
has exact synonym: attenuation reflex
has exact synonym: auditory reflex
has exact synonym: stapedius reflex
has OBO namespace: behavior_ontology

arthrokinetic reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex in which joint movement can reflexively cause muscle activation or inhibition." [wikpedia:Arthrokinetic_reflex]
date: 2011-04-07T05:42:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

cough reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex by which the body rids the lower respiratory tract of any irritant that enters through the air and less frequently any fluids (drinks) and solids (food) that may spill into the respiratory tract." [XX:http\://www.healthhype.com/cough-reflex-physiology-process-ear-cough-reflexes.html]
date: 2011-04-07T05:45:22Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

snout reflex
type: Class
subclass of: primitive reflex
definition: "A pouting or pursing of the lips that is elicited by light tapping of the closed lips near the midline." [wikipedia:Snout_reflex]
date: 2011-04-07T05:47:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

glabellar reflex
type: Class
subclass of: primitive reflex
definition: "A reflex elicited by repetitive tapping on the forehead which result in blinking to the first several taps." [wikipedia:Glabellar_reflex]
date: 2011-04-07T05:48:07Z
created by: George Gkoutos
has exact synonym: glabellar tap sign
has OBO namespace: behavior_ontology

Golgi tendon reflex
type: Class
subclass of: reflexive behavior
definition: "A skeletal muscle contraction causes the muscle to simultaneously lengthen and relax." [wikipedia:Golgi_tendon_reflex]
date: 2011-04-08T12:01:59Z
created by: George Gkoutos
has exact synonym: inverse myotatic reflex
has OBO namespace: behavior_ontology

shivering reflex
type: Class
subclass of: reflexive behavior
definition: A reflex in which muscle groups around the vital organs begin to shake in small movements in an attempt to create warmth by expending energy.
date: 2011-04-08T12:05:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: The shivering reflex is triggered to maintain homeostasis.

Axiom
annotated source: shivering reflex
annotated property: definition
annotated target: A reflex in which muscle groups around the vital organs begin to shake in small movements in an attempt to create warmth by expending energy.
source: wikipedia:Shivering

sternutation
type: Class
subclass of: reflexive behavior
definition: A reflex in which mucus containing foreign particles or irritants is expelled and the nasal cavity is cleanses.
date: 2011-04-08T12:08:31Z
created by: George Gkoutos
has exact synonym: sneeze
has exact synonym: sneezing
has OBO namespace: behavior_ontology

Axiom
annotated source: sternutation
annotated property: definition
annotated target: A reflex in which mucus containing foreign particles or irritants is expelled and the nasal cavity is cleanses.
source: wikipedia:Sneeze

vagovagal reflex
type: Class
subclass of: reflexive behavior
definition: "A contraction of muscles in the gastrointestinal tract in response to distension of the tract following consumption of food and drink." [wikipedia:Vagus_reflex]
date: 2011-04-08T12:10:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

eye movement
type: Class
subclass of: body part movement
date: 2011-04-08T12:22:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

tail movement
type: Class
subclass of: body part movement
date: 2011-04-08T12:22:13Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

visual pursuit
type: Class
subclass of: visual perception
subclass of: visual behavior
definition: Selective tracking that follows a moving object by eye.
contributor: https://orcid.org/0000-0002-4277-2151
date: 2011-04-08T12:25:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Original definition: Selectively track a moving object (Source: NBO:GVG).

locomotor activation behavior
type: Class
subclass of: kinesthetic behavior
subclass of: Restriction
  on property: part of
  some values from: locomotory behavior
definition: Activation of locomotory behavior.
date: 2011-04-08T12:27:51Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

vertical activity
type: Class
subclass of: locomotory behavior
date: 2011-04-08T12:28:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

spontaneous movement behavior
type: Class
subclass of: kinesthetic behavior
definition: Kinesthetic behavior initiated in the absence of specific sensory input.
date: 2011-04-08T12:28:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

social grooming
type: Class
subclass of: social behavior
subclass of: grooming behavior
definition: "Behavior related to the activity in which individuals in a group clean or maintain one another's body or appearance." [wikipedia:Social_grooming]
date: 2011-04-08T12:35:02Z
created by: George Gkoutos
has exact synonym: allo-hygiene behavior
has exact synonym: allogrooming
has exact synonym: allohygiene
has OBO namespace: behavior_ontology

personal grooming
type: Class
subclass of: grooming behavior
definition: "Behavior related to the promotion of personal hygiene." [wikipedia:Social_grooming]
date: 2011-04-08T12:35:54Z
created by: George Gkoutos
has alternative id: NBO:0000058
has exact synonym: auto-grooming
has exact synonym: autohygiene
has exact synonym: preening
has exact synonym: self-grooming
has OBO namespace: behavior_ontology

awareness
type: Class
subclass of: consciousness behavior
definition: Behavior related to the state or ability to perceive, to feel, or to be conscious of events, objects or sensory patterns.
date: 2011-04-08T12:50:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: awareness
annotated property: definition
annotated target: Behavior related to the state or ability to perceive, to feel, or to be conscious of events, objects or sensory patterns.
source: wikipedia:Awareness

obsolete behavior related to feelings experiencing
type: Class
date: 2011-04-08T12:52:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
deprecated: true

attention behavior
type: Class
subclass of: sensation behavior
definition: The sustained focus of cognitive resources on information while filtering or ignoring extraneous information. Intended to encompass only attention to perceptual stimuli.
date: 2011-04-08T01:02:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: attention behavior
annotated property: definition
annotated target: The sustained focus of cognitive resources on information while filtering or ignoring extraneous information. Intended to encompass only attention to perceptual stimuli.
source: wikipedia:Attention

focused attention behavior
type: Class
subclass of: attention behavior
definition: Behavior involving responding discretely to specific visual, auditory or tactile stimuli.
date: 2011-04-08T01:04:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: focused attention behavior
annotated property: definition
annotated target: Behavior involving responding discretely to specific visual, auditory or tactile stimuli.
source: wikipedia:Attention

selective attention behavior
type: Class
subclass of: attention behavior
definition: Behavior involving maintaining a behavioral or cognitive set in the face of distracting or competing stimuli.
date: 2011-04-08T01:05:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: selective attention behavior
annotated property: definition
annotated target: Behavior involving maintaining a behavioral or cognitive set in the face of distracting or competing stimuli.
source: wikipedia:Attention

alternating attention behavior
type: Class
subclass of: attention behavior
definition: Behavior involving mental flexibility that allows individuals to shift their focus of attention and move between tasks having different cognitive requirements.
date: 2011-04-08T01:05:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alternating attention behavior
annotated property: definition
annotated target: Behavior involving mental flexibility that allows individuals to shift their focus of attention and move between tasks having different cognitive requirements.
source: wikipedia:Attention

sustained attention behavior
type: Class
subclass of: attention behavior
definition: Behavior involving maintaining a consistent behavioral response during continuous and repetitive activity.
date: 2011-04-08T01:06:00Z
created by: George Gkoutos
has exact synonym: vigilance
has OBO namespace: behavior_ontology

Axiom
annotated source: sustained attention behavior
annotated property: definition
annotated target: Behavior involving maintaining a consistent behavioral response during continuous and repetitive activity.
source: wikipedia:Attention

divided attention behavior
type: Class
subclass of: attention behavior
definition: Behavior involving responding simultaneously to multiple tasks or multiple task demands.
date: 2011-04-08T01:08:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: divided attention behavior
annotated property: definition
annotated target: Behavior involving responding simultaneously to multiple tasks or multiple task demands.
source: wikipedia:Attention

size constancy behavior
type: Class
equivalent class: Class
  intersection of: perceptual constancy behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000117
subclass of: perceptual constancy behavior
subclass of: spatial perception
definition: "The perception of familiar objects as approximately the same size regardless of their distance from the observer." [Jrank:http\://science.jrank.org/pages/5094/Perception.html]
date: 2011-04-08T01:15:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

colour constancy behavior
type: Class
equivalent class: Class
  intersection of: perceptual constancy behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000014
subclass of: perceptual constancy behavior
subclass of: Restriction
  on property: is_about
  some values from: PATO_0000014
definition: "The perception of a color as constant under changing conditions of illumination." [wikipedia:Color_constancy]
date: 2011-04-08T01:16:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

shape constancy behavior
type: Class
equivalent class: Class
  intersection of: perceptual constancy behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000052
subclass of: perceptual constancy behavior
subclass of: form perception behavior
definition: The perception of familiar objects as approximately the same shape regardless of their distance or angle of view from the observer.
date: 2011-04-08T01:18:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: shape constancy behavior
annotated property: definition
annotated target: The perception of familiar objects as approximately the same shape regardless of their distance or angle of view from the observer.
source: NBO:GVG

perception of motion behavior
type: Class
subclass of: sensation behavior
definition: "Perception relating to the process of inferring the speed and direction of elements in a scene based on visual, vestibular and proprioceptive inputs." [wikipedia:Motion_perception]
date: 2011-04-08T01:23:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

form perception behavior
type: Class
equivalent class: Class
  intersection of: sensation behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000052
subclass of: sensation behavior
subclass of: Restriction
  on property: is_about
  some values from: PATO_0000052
definition: "Perception related to the identification of objects and their distinction from each other." [:http\://science.jrank.org/pages/5094/Perception.html]
date: 2011-04-08T01:25:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

depth perception behavior
type: Class
equivalent class: Class
  intersection of: sensation behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0001595
subclass of: spatial perception
subclass of: Restriction
  on property: is_about
  some values from: PATO_0001595
definition: "Behavior involving an active reception and coordination of information relating to depth received through the sensory systems in order to perceive the three-dimensionality of the world and objects within it." [:erceiving the three-dimensionality of the world and objects Read more\: Perception - Perceptual Systems\, Historical Background\, Innate And Learned - Classical perceptual phenomena\, Broad theoretical approaches\, Current research/future developments http\://science.jrank.org/pages/5094/Perception.html#ixzz1It3oOobp]
date: 2011-04-08T01:29:05Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

distance perception behavior
type: Class
equivalent class: Class
  intersection of: spatial perception
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000040
subclass of: spatial perception
subclass of: Restriction
  on property: is_about
  some values from: PATO_0000040
definition: Perception of the distance of an object.
date: 2011-04-08T01:31:08Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: distance perception behavior
annotated property: definition
annotated target: Perception of the distance of an object.
source: NBO:GVG

perceptual illusion behavior
type: Class
subclass of: sensation behavior
definition: "Misperception of stimuli, where what is perceived does not correspond to the actual dimensions or qualities of the physical stimulus." [jrank:http\://science.jrank.org/pages/5094/Perception.html]
date: 2011-04-08T01:32:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

stress related behavior
type: Class
subclass of: behavior process
definition: "Behavior related to how the body reacts to a stressor ( a stimulus that causes stress), real or imagined." [wikipedia:Stress_(biological)]
date: 2011-04-08T01:52:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: It refers to the consequence of the failure of an organism to respond adequately to mental, emotional or physical demands, whether actual or imagined.

behavioral alarm
type: Class
subclass of: stress related behavior
definition: "Behavior related to the identification or realization of a threat or a stressor." [wikipedia:Stress_(biological)]
date: 2011-04-08T01:55:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

predator avoidance behavior
type: Class
subclass of: acute stress response
subclass of: retreat behavior
date: 2011-04-08T02:00:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

behavioral exhaustion
type: Class
subclass of: stress related behavior
definition: Behavior related to the depletion of the body resources for coping to stress.
date: 2011-04-08T02:06:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral exhaustion
annotated property: definition
annotated target: Behavior related to the depletion of the body resources for coping to stress.
source: NBO:GVG

rhythmic behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: rhythmic behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: rhythmic behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2011-04-08T02:18:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

circadian behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: rhythmic behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2011-04-08T02:19:42Z
created by: George Gkoutos
has exact synonym: pathological circadian behaviour
has OBO namespace: behavior_ontology

dyssomnia
type: Class
subclass of: sleeping behavior phenotype
definition: A pathological sleeping behavior related to the initiating or maintaining sleep or of excessive sleepiness and are characterized by a disturbance in the amount, quality, or timing of sleep.
date: 2011-04-08T02:20:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: dyssomnia
annotated property: definition
annotated target: A pathological sleeping behavior related to the initiating or maintaining sleep or of excessive sleepiness and are characterized by a disturbance in the amount, quality, or timing of sleep.
source: wikipedia:Dyssomnia

intrinsic sleep disorder
type: Class
subclass of: dyssomnia
date: 2011-04-08T02:21:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

hypersomnia
type: Class
subclass of: intrinsic sleep disorder
definition: A dyssomnia characterized by excessive amounts of sleepiness.
date: 2011-04-08T02:26:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hypersomnia
annotated property: definition
annotated target: A dyssomnia characterized by excessive amounts of sleepiness.
source: wikipedia:Hypersomnia

periodic limb movement disorder
type: Class
subclass of: intrinsic sleep disorder
definition: "A dyssomnia where the patient moves limbs involuntarily during sleep, and has symptoms or problems related to the movement." [wikipedia:Periodic_limb_movement_disorder]
date: 2011-04-08T02:27:28Z
created by: George Gkoutos
has exact synonym: PLMD
has exact synonym: nocturnal myoclonus
has OBO namespace: behavior_ontology

restless legs syndrome
type: Class
subclass of: intrinsic sleep disorder
definition: "A dyssomnia characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations." [wikipedia:Restless_legs_syndrome]
date: 2011-04-08T02:28:45Z
created by: George Gkoutos
has exact synonym: RLS
has exact synonym: Wittmaack Ekbom syndrome
has OBO namespace: behavior_ontology

sleep apnea
type: Class
subclass of: sleep breathing disorder
definition: "A sleep breathing disorder characterized by abnormal pauses in breathing or instances of abnormally low breathing, during sleep." [wikipedia:Sleep_apnea]
date: 2011-04-08T02:30:29Z
created by: George Gkoutos
has exact synonym: sleep apnoea
has OBO namespace: behavior_ontology

sleep state misperception
type: Class
subclass of: intrinsic sleep disorder
definition: "A dyssomnia characterized by a mistakenly perception of one's sleep as wakefulness." [wikipedia:Sleep_state_misperception]
date: 2011-04-08T02:31:33Z
created by: George Gkoutos
has exact synonym: SSM
has exact synonym: paradoxical insomnia
has exact synonym: pseudo-insomnia
has exact synonym: sleep hypochondriasis
has exact synonym: subjective insomnia
has exact synonym: subjective sleepiness
has OBO namespace: behavior_ontology

extrinsic sleep disorder
type: Class
subclass of: dyssomnia
date: 2011-04-08T02:35:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

alcohol-dependent sleep disorder
type: Class
subclass of: extrinsic sleep disorder
definition: A dyssomnia associated with alcohol intake.
date: 2011-04-08T02:36:22Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alcohol-dependent sleep disorder
annotated property: definition
annotated target: A dyssomnia associated with alcohol intake.
source: NBO:GVG

food allergy insomnia
type: Class
subclass of: extrinsic sleep disorder
definition: A insomnia associated with food allergies.
date: 2011-04-08T02:37:51Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: food allergy insomnia
annotated property: definition
annotated target: A insomnia associated with food allergies.
source: NBO:GVG

circadian rhythm sleep disorder
type: Class
subclass of: circadian behavior phenotype
subclass of: dyssomnia
definition: "A pathological circadian behavior primarily related to the timing of sleep." [wikipedia:Circadian_rhythm_sleep_disorder]
date: 2011-04-08T02:38:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

extrinsic circadian rhythm sleep disorder
type: Class
subclass of: circadian rhythm sleep disorder
definition: "An extrinsic circadian rhythm sleep disorder characterized by insomnia and excessive sleepiness affecting people whose work hours are scheduled during the typical sleep period." [wikipedia:Shift_work_sleep_disorder]
date: 2011-04-08T02:54:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

intrinsic circadian rhythm sleep disorder
type: Class
subclass of: circadian rhythm sleep disorder
date: 2011-04-08T02:54:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

jet lag
type: Class
subclass of: extrinsic circadian rhythm sleep disorder
definition: "An extrinsic circadian rhythm sleep disorder resulting from rapid long distance transmeridian (east west or west east) travel." [wikipedia:Jet_lag]
date: 2011-04-08T02:55:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

shift work sleep disorder
type: Class
subclass of: extrinsic circadian rhythm sleep disorder
date: 2011-04-08T02:57:20Z
created by: George Gkoutos
has exact synonym: SWSD
has OBO namespace: behavior_ontology

advanced sleep phase syndrome
type: Class
subclass of: intrinsic circadian rhythm sleep disorder
definition: "A circadian rhythm sleep disorder characterized by difficulty staying awake in the evening and staying asleep in the morning." [wikipedia:Advanced_sleep_phase_syndrome]
date: 2011-04-08T03:00:14Z
created by: George Gkoutos
has exact synonym: ASPS
has exact synonym: ASPT
has exact synonym: advanced sleep-phase type
has OBO namespace: behavior_ontology

non-24-hour sleep-wake syndrome
type: Class
subclass of: intrinsic circadian rhythm sleep disorder
definition: "A circadian rhythm sleep disorder which the affected individual's sleep occurs later and later each day, with the period of peak alertness also continuously moving around the clock from day to day." [wikipedia:Circadian_rhythm_sleep_disorder]
date: 2011-04-08T03:11:40Z
created by: George Gkoutos
has exact synonym: circadian rhythm sleep disorder, free running type
has exact synonym: circadian rhythm sleep disorder, nonentrained type
has exact synonym: free running disorder (FRD)
has exact synonym: hypernychthemeral syndrome
has exact synonym: non-24
has exact synonym: non-24-hour circadian rhythm disorder
has exact synonym: non-24-hour sleep-wake disorder
has OBO namespace: behavior_ontology

irregular sleep-wake rhythm
type: Class
subclass of: intrinsic circadian rhythm sleep disorder
definition: "A circadian rhythm sleep disorder characterized by numerous naps throughout the 24-hour period, no main night time sleep episode and irregularity from day to day." [wikipedia:Irregular_sleep-wake_rhythm]
date: 2011-04-08T03:16:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

parasomnia
type: Class
subclass of: sleeping behavior phenotype
definition: A sleeping behavior phenotype that involve abnormal and unnatural movements, emotions, perceptions, and dreams that occur while falling asleep, sleeping, between sleep stages, or during arousal from sleep.
date: 2011-04-08T03:20:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: parasomnia
annotated property: definition
annotated target: A sleeping behavior phenotype that involve abnormal and unnatural movements, emotions, perceptions, and dreams that occur while falling asleep, sleeping, between sleep stages, or during arousal from sleep.
source: wikipedia:Parasomnia

sleep breathing disorder
type: Class
subclass of: intrinsic sleep disorder
definition: An intrinsic sleep disorder characterised by breathing abnormalities.
date: 2011-04-08T03:27:40Z
created by: George Gkoutos
has exact synonym: SBD
has OBO namespace: behavior_ontology

Axiom
annotated source: sleep breathing disorder
annotated property: definition
annotated target: An intrinsic sleep disorder characterised by breathing abnormalities.
source: NBO:GVG

snoring
type: Class
subclass of: sleeping behavior
definition: A sleeping behavior characterised by vibration of respiratory structures and the resulting sound, due to obstructed air movement during breathing while sleeping.
date: 2011-04-08T03:28:23Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: snoring
annotated property: definition
annotated target: A sleeping behavior characterised by vibration of respiratory structures and the resulting sound, due to obstructed air movement during breathing while sleeping.
source: wikipedia:Snoring

upper airway resistance syndrome
type: Class
subclass of: sleep breathing disorder
definition: "A sleep breathing disorder characterized by airway resistance to breathing during sleep." [wikipedia:Upper_airway_resistance_syndrome]
date: 2011-04-08T03:30:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

recurrent hypersomnia
type: Class
subclass of: hypersomnia
definition: A hypersomnia characterized by recurrent episodes.
date: 2011-04-08T03:32:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: recurrent hypersomnia
annotated property: definition
annotated target: A hypersomnia characterized by recurrent episodes.
source: NBO:GVG

posttraumatic hypersomnia
type: Class
subclass of: hypersomnia
definition: A hypersomnia that occurs as a result of a traumatic event involving the central nervous system.
date: 2011-04-08T03:32:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: posttraumatic hypersomnia
annotated property: definition
annotated target: A hypersomnia that occurs as a result of a traumatic event involving the central nervous system.
source: NBO:GVG

NREM parasomnia
type: Class
subclass of: parasomnia
definition: A type of parasomnia that occurs during NREM sleep.
date: 2011-04-08T03:37:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: NREM parasomnia
annotated property: definition
annotated target: A type of parasomnia that occurs during NREM sleep.
source: NBO:GVG

sleepwalking
type: Class
subclass of: NREM parasomnia
definition: A NREM parasomnia characterised by the risef rom the slow wave sleep stage in a state of low consciousness and perform activities that are usually performed during a state of full consciousness.
date: 2011-04-09T09:32:07Z
created by: George Gkoutos
has exact synonym: somnambulism
has OBO namespace: behavior_ontology

Axiom
annotated source: sleepwalking
annotated property: definition
annotated target: A NREM parasomnia characterised by the risef rom the slow wave sleep stage in a state of low consciousness and perform activities that are usually performed during a state of full consciousness.
source: wikipedia:Sleepwalking

nocturnal enuresis
type: Class
subclass of: NREM parasomnia
definition: A NREM parasomnia characterised by involuntary urination while asleep after the age at which bladder control usually occurs.
date: 2011-04-09T09:39:54Z
created by: George Gkoutos
has exact synonym: bedwetting
has OBO namespace: behavior_ontology

Axiom
annotated source: nocturnal enuresis
annotated property: definition
annotated target: A NREM parasomnia characterised by involuntary urination while asleep after the age at which bladder control usually occurs.
source: wikipedia:Bedwetting

somniloquy
type: Class
subclass of: NREM parasomnia
definition: A NREM parasomnia characterised by talking during sleep.
date: 2011-04-09T10:02:28Z
created by: George Gkoutos
has exact synonym: sleep-talking
has OBO namespace: behavior_ontology

Axiom
annotated source: somniloquy
annotated property: definition
annotated target: A NREM parasomnia characterised by talking during sleep.
source: NBO:GVG

REM sleep behavior disorder
type: Class
subclass of: REM parasomnia
definition: "A REM parasomnia characterised by the lack of muscle atonia during sleep." [wikipedia:REM_Sleep_Behavior_Disorder]
date: 2011-04-09T10:06:44Z
created by: George Gkoutos
has exact synonym: RBD
has OBO namespace: behavior_ontology

REM parasomnia
type: Class
subclass of: parasomnia
definition: A type of parasomnia that occurs during REM sleep.
date: 2011-04-09T10:07:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: REM parasomnia
annotated property: definition
annotated target: A type of parasomnia that occurs during REM sleep.
source: NBO:GVG

acute RBD
type: Class
subclass of: REM sleep behavior disorder
definition: A RBD that occurs mostly as a result of a side-effect in prescribed medication- usually antidepressants.
date: 2011-04-09T10:10:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: acute RBD
annotated property: definition
annotated target: A RBD that occurs mostly as a result of a side-effect in prescribed medication- usually antidepressants.
source: wikipedia:Parasomnia

chronic RBD
type: Class
subclass of: REM sleep behavior disorder
definition: Idiopathic or associated with neurological disorders REM sleep behavior disorder.
date: 2011-04-09T10:11:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: chronic RBD
annotated property: definition
annotated target: Idiopathic or associated with neurological disorders REM sleep behavior disorder.
source: wikipedia:Parasomnia

catathrenia
type: Class
subclass of: REM parasomnia
definition: A REM parasomnia consisting of breath holding and expiratory groaning during sleep that is distinct from both somniloquy and obstructive sleep apnea.
date: 2011-04-09T10:13:44Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: catathrenia
annotated property: definition
annotated target: A REM parasomnia consisting of breath holding and expiratory groaning during sleep that is distinct from both somniloquy and obstructive sleep apnea.
source: wikipedia:Catathrenia

recurrent isolated sleep paralysis
type: Class
subclass of: isolated sleep paralysis
definition: "An isolted sleep paralysis that is characterized by frequent episodes or a complex of sequential episodes whose total duration may exceed one hour, and particularly by the range and sense of perceived reality of the subjective phenomena experienced during episodes." [web:http\://www.theconsciousdreamer.org/SSE.HTM]
date: 2011-04-09T10:14:54Z
created by: George Gkoutos
has exact synonym: RISP
has OBO namespace: behavior_ontology

isolated sleep paralysis
type: Class
subclass of: sleep paralysis
definition: "A sleep paralaysis characterised by the absence of narcolepsy." [wikipedia:Sleep_paralysis]
date: 2011-04-09T10:20:09Z
created by: George Gkoutos
has exact synonym: ISP
has OBO namespace: behavior_ontology

sleep paralysis
type: Class
subclass of: paralysis
subclass of: REM parasomnia
definition: "A REM parasomnia characterised by periods of inability to perform voluntary movements either when going to sleep or when waking up." [wikipedia:Sleep_paralysis]
date: 2011-04-09T10:24:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

hypnagogic sleep paralysis
type: Class
subclass of: sleep paralysis
definition: "A sleep paralysis which upon falling asleep the person remains aware while the body shuts down for REM sleep." [wikipedia:Sleep_paralysis]
date: 2011-04-09T10:25:40Z
created by: George Gkoutos
has exact synonym: predormital sleep paralysis
has OBO namespace: behavior_ontology

hypnopompic sleep paralysis
type: Class
subclass of: sleep paralysis
definition: "A sleep paralysis which upon awakening, the person becomes aware before the REM cycle is complete,." [wikipedia:Sleep_paralysis]
date: 2011-04-09T10:28:53Z
created by: George Gkoutos
has exact synonym: postdormital sleep paralysis
has OBO namespace: behavior_ontology

climbing stairs
type: Class
subclass of: climbing behavior
definition: Behavior related to the ascending stairs.
date: 2011-04-09T10:51:13Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: climbing stairs
annotated property: definition
annotated target: Behavior related to the ascending stairs.
source: NBO:GVG

hypnophobia
type: Class
subclass of: intrinsic sleep disorder
definition: A dyssomnia characterised by fear of sleep.
date: 2011-04-09T11:20:26Z
created by: George Gkoutos
has exact synonym: somniphobia
has OBO namespace: behavior_ontology

Axiom
annotated source: hypnophobia
annotated property: definition
annotated target: A dyssomnia characterised by fear of sleep.
source: NBO:GVG

depressive disorder
type: Class
equivalent class: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0002361
    intersection of: Restriction
      on property: towards
      some values from: depression behavior
subclass of: mood disorder
subclass of: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0002361
    intersection of: Restriction
      on property: towards
      some values from: depression behavior
date: 2011-04-09T12:28:31Z
created by: George Gkoutos
has alternative id: NBO:0000523
has exact synonym: DD-NOS
has exact synonym: depressive disorder not otherwise specified
has OBO namespace: behavior_ontology
xref: HP:0000716

atypical depression
type: Class
subclass of: major depressive disorder
definition: "A major depressive disorder characterized by mood reactivity (paradoxical anhedonia) and positivity, significant weight gain or increased appetite (\"comfort eating\"), excessive sleep or somnolence (hypersomnia), a sensation of heaviness in limbs known as leaden paralysis, and significant social impairment as a consequence of hypersensitivity to perceived interpersonal rejection." [wikipedia:Atypical_depression]
date: 2011-04-10T12:55:14Z
created by: George Gkoutos
has exact synonym: AD
has OBO namespace: behavior_ontology

melancholic depression
type: Class
subclass of: major depressive disorder
definition: "A major depressive disorder characterized by a loss of pleasure (anhedonia) in most or all activities, a failure of reactivity to pleasurable stimuli, a quality of depressed mood more pronounced than that of grief or loss, a worsening of symptoms in the morning hours, early morning waking, psychomotor retardation, excessive weight loss (not to be confused with anorexia nervosa), or excessive guilt." [wikipedia:Melancholic_depression]
date: 2011-04-10T12:57:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

psychotic major depression
type: Class
subclass of: major depressive disorder
definition: "A major depressive disorder characterized by a major depressive episode, particularly of melancholic nature, where the patient experiences psychotic symptoms such as delusions or, less commonly, hallucinations." [wikipedia:Psychotic_major_depression]
date: 2011-04-10T12:58:44Z
created by: George Gkoutos
has exact synonym: PMD
has OBO namespace: behavior_ontology

catatonic depression
type: Class
subclass of: major depressive disorder
definition: A major depressive disorder characterized by psychological and motorological disturbances.
date: 2011-04-10T01:01:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: catatonic depression
annotated property: definition
annotated target: A major depressive disorder characterized by psychological and motorological disturbances.
source: wikipedia:Catatonia

postpartum depression
type: Class
subclass of: major depressive disorder
definition: "A major depressive disorder characterized by a intense, sustained and sometimes disabling depression experienced by women after giving birth." [wikipedia:Postpartum_depression]
date: 2011-04-10T01:03:17Z
created by: George Gkoutos
has exact synonym: PDD
has exact synonym: postnatal depression
has OBO namespace: behavior_ontology

seasonal affective disorder
type: Class
subclass of: major depressive disorder
definition: "A major depressive disorder usually characterized seasonal pattern with depressive episodes coming on in the winter or summer, spring or autumn, repeatedly, year after year." [wikipedia:Seasonal_affective_disorder]
date: 2011-04-10T01:10:46Z
created by: George Gkoutos
has exact synonym: winter blues
has exact synonym: winter depression
has OBO namespace: behavior_ontology

dysthymia
type: Class
subclass of: depressive disorder
definition: A depressive disorder characterized by chronic, different mood disturbance.
date: 2011-04-10T01:13:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: For humans: where a person reports a low mood almost daily over a span of at least two years.

Axiom
annotated source: dysthymia
annotated property: definition
annotated target: A depressive disorder characterized by chronic, different mood disturbance.
source: wikipedia:Dysthymia

recurrent brief depression
type: Class
subclass of: depressive disorder
definition: "A depressive disorder characterized by intermittent depressive episodes, in women not related to menstrual cycles, occurring at least once a month over at least one year or more fulfilling the diagnostic criteria for major depressive episodes except for duration which in RBD is less than 14 days, typically 2 to 4 days." [wikipedia:Recurrent_brief_depression]
date: 2011-04-10T01:17:54Z
created by: George Gkoutos
has exact synonym: RBD
has OBO namespace: behavior_ontology

minor depressive disorder
type: Class
subclass of: depressive disorder
definition: "A depressive disorder that does not meet full criteria for Major depressive disorder but in which at least two depressive symptoms are present for two weeks." [wikipedia:Minor_Depressive_Disorder]
date: 2011-04-10T01:19:53Z
created by: George Gkoutos
has exact synonym: minor depression
has OBO namespace: behavior_ontology

bipolar I
type: Class
subclass of: bipolar disorder
definition: "A type of bipolar disorder distinguished by the presence or history of one or more manic episodes or mixed episodes with or without major depressive episodes." [wikipedia:Bipolar_I]
date: 2011-04-10T01:25:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

bipolar II
type: Class
subclass of: bipolar disorder
definition: "A bipolar disorder characterised by recurrent intermittent hypomanic and depressive episodes." [wikipedia:Mood_disorder]
date: 2011-04-10T01:26:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

cyclothymia
type: Class
subclass of: bipolar disorder
definition: A bipolar disorder characterised by recurrent hypomanic and dysthymic episodes, but no full manic episodes or full major depressive episodes.
date: 2011-04-10T01:27:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cyclothymia
annotated property: definition
annotated target: A bipolar disorder characterised by recurrent hypomanic and dysthymic episodes, but no full manic episodes or full major depressive episodes.
source: wikipedia:Cyclothymia

bipolar disorder not otherwise specified
type: Class
subclass of: bipolar disorder
definition: "A bipolar disorder characterised by symptoms in the bipolar spectrum (e.g. manic and depressive symptoms) but does not fully qualify for any of the three types of bipolar disorder." [wikipedia:Bipolar_Disorder_Not_Otherwise_Specified]
date: 2011-04-10T01:28:33Z
created by: George Gkoutos
has exact synonym: BD-NOS
has OBO namespace: behavior_ontology

substance induced mood disorder
type: Class
subclass of: mood disorder
date: 2011-04-10T01:33:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

alcohol induced mood disorder
type: Class
subclass of: substance induced mood disorder
date: 2011-04-10T01:34:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

benzodiazepine induced mood disorder
type: Class
subclass of: substance induced mood disorder
date: 2011-04-10T01:34:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Interferon-alpha induced mood disorder
type: Class
subclass of: substance induced mood disorder
date: 2011-04-10T01:34:41Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

post-traumatic stress
type: Class
subclass of: pathological anxiety
definition: "A pathological anxiety which results from a traumatic experience." [wikipedia:Post-traumatic_stress_disorder]
date: 2011-04-10T01:42:56Z
created by: George Gkoutos
has exact synonym: PTSD
has exact synonym: post-traumatic stress disorder
has OBO namespace: behavior_ontology

separation anxiety
type: Class
subclass of: pathological anxiety
definition: "A pathological anxiety characterized by feeling of excessive and inappropriate levels of anxiety over being separated from a person or place." [wikipedia:Separation_anxiety_disorder]
date: 2011-04-10T01:44:22Z
created by: George Gkoutos
has exact synonym: SepAD
has OBO namespace: behavior_ontology

circadian regulation of heart rate
type: Class
subclass of: circadian behavior
definition: Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.
date: 2011-04-10T02:18:47Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: GO:0003053

Axiom
annotated source: circadian regulation of heart rate
annotated property: definition
annotated target: Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.
source: GOC:rl

circadian regulation of systemic arterial blood pressure
type: Class
subclass of: circadian behavior
definition: "Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours." [GO:GO\:0003052]
date: 2011-04-10T02:21:01Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

circadian temperature homeostasis
type: Class
subclass of: thermoregulation behavior
subclass of: circadian behavior
definition: Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.
date: 2011-04-10T02:22:58Z
created by: George Gkoutos
has exact synonym: circadian thermoregulation
has OBO namespace: behavior_ontology

Axiom
annotated source: circadian temperature homeostasis
annotated property: definition
annotated target: Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.
source: GOC:dbh

eating behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: eating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: feeding behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: eating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of feeding behavior that relates to eating.
date: 2011-04-10T10:39:39Z
created by: George Gkoutos
has exact synonym: eating disorder
has OBO namespace: behavior_ontology

Axiom
annotated source: eating behavior phenotype
annotated property: definition
annotated target: Observable characteristic of feeding behavior that relates to eating.
source: NBO:GVG

drinking behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: feeding behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of feeding behavior that relates to drinking.
date: 2011-04-10T10:40:49Z
created by: George Gkoutos
has exact synonym: drinking disorder
has exact synonym: pathological drinking behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: drinking behavior phenotype
annotated property: definition
annotated target: Observable characteristic of feeding behavior that relates to drinking.
source: NBO:GVG

dipsosis
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction
subclass of: increased frequency of drinking
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction
definition: A pathological drinking behavior characterised by an excessive desire to drink.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
note: 'participates in' some ('regulation of drinking behavior' and (has_quality some ('increased frequency' and towards some 'liquid consumption' and owl:qualifier some chronic)))
xref: MP:0002119

Axiom
annotated source: dipsosis
annotated property: definition
annotated target: A pathological drinking behavior characterised by an excessive desire to drink.
source: NBO:GVG

polydipsia
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: Class
      intersection of: regulation of drinking behavior
      intersection of: Restriction
        on property: regulates
        some values from: liquid consumption
      intersection of: Restriction
        on property: has-input
        some values from: Class
    intersection of: Restriction
      on property: qualifier
      some values from: PATO_0001333
subclass of: drinking behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: Class
      intersection of: regulation of drinking behavior
      intersection of: Restriction
        on property: regulates
        some values from: liquid consumption
      intersection of: Restriction
        on property: has-input
        some values from: Class
    intersection of: Restriction
      on property: qualifier
      some values from: PATO_0001333
definition: A pathological drinking behavior characterised by large intake of fluids by mouth, usually due to excessive thirst that is relatively prolonged.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
note: 'participates in' some ( 'regulation of drinking behavior' and regulates some ('liquid consumption' and has-input some ('liquid substance' and has_quality some 'increased mass')) and owl:qualifier some 'temporally extended')
xref: HP:0001959
xref: MP:0001426

Axiom
annotated source: polydipsia
annotated property: definition
annotated target: A pathological drinking behavior characterised by large intake of fluids by mouth, usually due to excessive thirst that is relatively prolonged.
source: NBO:GVG

hyperdipsia
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction
subclass of: increased frequency of drinking
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction
definition: A pathological drinking behavior characterised by an excessive relative temporal desire to drink.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
note: 'participates in' some ('regulation of drinking behavior' and (has_quality some ('increased frequency' and (towards some 'liquid consumption') and (owl:qualifier some 'temporally extended'))))
xref: MP:0005111

Axiom
annotated source: hyperdipsia
annotated property: definition
annotated target: A pathological drinking behavior characterised by an excessive relative temporal desire to drink.
source: NBO:GVG

aphagia
type: Class
equivalent class: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: towards
      some values from: eating behavior
subclass of: eating behavior phenotype
subclass of: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: towards
      some values from: eating behavior
definition: A pathological feeding behavior characterised by failure to eat.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0001438

Axiom
annotated source: aphagia
annotated property: definition
annotated target: A pathological feeding behavior characterised by failure to eat.
source: NBO:GVG

swallowing
type: Class
subclass of: feeding behavior
subclass of: Restriction
  on property: part of
  some values from: feeding behavior
definition: The act of moving food from the mouth cavity to the esophagus through coordinated muscular movements [NBO:AC]
date: 2011-04-10T10:39:39Z
created by: George Gkoutos
has exact synonym: swallow
has OBO namespace: behavior_ontology

polyphagia
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: food consumption
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
subclass of: eating behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: food consumption
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000912
definition: A pathological eating behavior characterised by an abnormally large intake of food by mouth, usually due to excessive hunger that is relatively prolonged.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has exact synonym: hyperphagia
has OBO namespace: behavior_ontology
xref: HP:0000724
xref: MP:0001433

Axiom
annotated source: polyphagia
annotated property: definition
annotated target: A pathological eating behavior characterised by an abnormally large intake of food by mouth, usually due to excessive hunger that is relatively prolonged.
source: NBO:GVG

anhedonia
type: Class
equivalent class: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: towards
      some values from: pleasure behavior
subclass of: dysthymia
subclass of: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: towards
      some values from: pleasure behavior
definition: Lack of ability to enjoy a sense of pleasure.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0009710

Axiom
annotated source: anhedonia
annotated property: definition
annotated target: Lack of ability to enjoy a sense of pleasure.
source: NBO:GVG

male sexual activity
type: Class
subclass of: sexual activity
definition: Behaviour related to the male activity which primary purpose is the sexual reproduction.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: male sexual activity
annotated property: definition
annotated target: Behaviour related to the male activity which primary purpose is the sexual reproduction.
source: NBO:GVG

female sexual activity
type: Class
subclass of: sexual activity
definition: Behaviour related to the female activity which primary purpose is the sexual reproduction.
date: 2011-04-10T10:41:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: female sexual activity
annotated property: definition
annotated target: Behaviour related to the female activity which primary purpose is the sexual reproduction.
source: NBO:GVG

recognition memory
type: Class
subclass of: declarative memory
definition: "Ability to correctly remember something that has been encountered before." [wikipedia:Recognition_memory]
date: 2011-04-14T01:53:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

visual object recognition
type: Class
subclass of: recognition memory
definition: "Ability to perceive the physical properties of an object (such as shape, colour and texture) and apply semantic attributes to the object, which includes the understanding of its use, previous experience with the object and how it relates to others." [wikipedia:Cognitive_Neuroscience_of_Visual_Object_Recognition]
date: 2011-04-14T01:56:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

long term object recognition memory
type: Class
subclass of: visual object recognition
definition: A visual object recognition that lasts hours to months and critically depends on a transfer of the information from short term object recognition memory using repeated rehearsals.
date: 2011-04-14T02:02:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: long term object recognition memory
annotated property: definition
annotated target: A visual object recognition that lasts hours to months and critically depends on a transfer of the information from short term object recognition memory using repeated rehearsals.
source: NBO:GVG

short term object recognition memory
type: Class
subclass of: visual short term memory
date: 2011-04-14T02:03:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

visual short term memory
type: Class
subclass of: short-term memory
date: 2011-04-14T02:09:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

spatial working memory
type: Class
subclass of: short-term memory
subclass of: spatial memory
date: 2011-04-14T02:10:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

spatial memory
type: Class
subclass of: memory storage behavior
definition: "A type of memory responsible for recording information about one's environment and its spatial orientation." [wikipedia:Spatial_memory]
date: 2011-04-14T02:14:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

short term spatial memory
type: Class
subclass of: spatial memory
definition: "A type of memory that allows one to temporarily store and manage information about one's environment and its spatial orientation." [wikipedia:Spatial_memory]
date: 2011-04-14T02:17:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

long term spatial memory
type: Class
subclass of: declarative memory
date: 2011-04-14T02:19:43Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

maternal grooming
type: Class
subclass of: maternal nurturing behavior
subclass of: social grooming
definition: Behavior related to the activity in which a mother cleans or maintains the body or the appearance of her offsprings.
date: 2011-04-14T07:58:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: maternal grooming
annotated property: definition
annotated target: Behavior related to the activity in which a mother cleans or maintains the body or the appearance of her offsprings.
source: NBO:GVG

barbering behavior
type: Class
subclass of: grooming behavior
definition: Behavior relating to the plucking of fur/hair or whiskers/vibrissae.
date: 2011-04-14T08:03:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: barbering behavior
annotated property: definition
annotated target: Behavior relating to the plucking of fur/hair or whiskers/vibrissae.
source: NBO:GVG

hetero-barbering
type: Class
subclass of: barbering behavior
definition: Behavior related to the barbering of other individuals of a cohort.
date: 2011-04-14T08:04:13Z
created by: George Gkoutos
has alternative id: NBO:0000083
has exact synonym: whisker trimming
has OBO namespace: behavior_ontology
xref: MP:0001446

Axiom
annotated source: hetero-barbering
annotated property: definition
annotated target: Behavior related to the barbering of other individuals of a cohort.
source: NBO:GVG

self-barbering
type: Class
subclass of: barbering behavior
definition: Behavior related to the barbering of oneself.
date: 2011-04-14T08:05:32Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: self-barbering
annotated property: definition
annotated target: Behavior related to the barbering of oneself.
source: NBO:GVG

catalepsy
type: Class
subclass of: posture phenotype
definition: A pathological behavior characterized by muscular rigidity and fixation of posture regardless of external stimuli, as well as decreased sensitivity to pain.
date: 2011-04-14T08:14:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0002822

Axiom
annotated source: catalepsy
annotated property: definition
annotated target: A pathological behavior characterized by muscular rigidity and fixation of posture regardless of external stimuli, as well as decreased sensitivity to pain.
source: wikipedia:Catalepsy

social behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: social behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: social behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior that occurs predominantly or only, in individuals that are part of a group.
date: 2011-04-14T08:24:37Z
created by: George Gkoutos
has exact synonym: pathological social behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: social behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior that occurs predominantly or only, in individuals that are part of a group.
source: NBO:GVG

social withdrawal
type: Class
subclass of: social behavior phenotype
date: 2011-04-14T08:24:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0001361

social withdrawal in childhood
type: Class
subclass of: social withdrawal
date: 2011-04-14T08:25:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

stereotypic behavior
type: Class
subclass of: voluntary movement behavior phenotype
definition: A pathological behavior associated with repetitive or ritualistic movement, posture, or utterance.
date: 2011-04-14T08:28:29Z
created by: George Gkoutos
has exact synonym: stereotypic behaviour
has exact synonym: stereotypy
has OBO namespace: behavior_ontology
xref: HP:0000733
xref: MP:0001408

Axiom
annotated source: stereotypic behavior
annotated property: definition
annotated target: A pathological behavior associated with repetitive or ritualistic movement, posture, or utterance.
source: wikipedia:Stereotypy

kinesthetic behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: kinesthetic behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: kinesthetic behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the movement of the body's muscles, tendons, and joints.
date: 2011-04-14T08:31:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: kinesthetic behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the movement of the body's muscles, tendons, and joints.
source: NBO:GVG

fatigue
type: Class
subclass of: voluntary movement behavior phenotype
definition: Exhibiting abnormal exhaustion due to mental or physical exertion.
date: 2011-04-14T08:32:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0002899

Axiom
annotated source: fatigue
annotated property: definition
annotated target: Exhibiting abnormal exhaustion due to mental or physical exertion.
source: NBO:GVG

head bobbing
type: Class
subclass of: head movement
definition: Movement of the head in the vertical plane. [NBO:GVG]
date: 2011-04-14T08:39:38Z
created by: George Gkoutos
has exact synonym: head nodding
has exact synonym: nod head
has OBO namespace: behavior_ontology

multidirectional head movement
type: Class
subclass of: head movement
definition: Movement of the head in multiple directions.
date: 2011-04-14T08:43:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: multidirectional head movement
annotated property: definition
annotated target: Movement of the head in multiple directions.
source: NBO:GVG

senility
type: Class
subclass of: cognitive behavior phenotype
definition: "A degenerative state of the brain resulting in impairment of memory, judgment, attention span, problem solving skills, the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function, and a global loss of cognitive abilities." [MeSH:National Library of Medicine_Medical Subject Headings]
date: 2011-04-14T09:01:45Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0002571

behavioral despair
type: Class
subclass of: depressive disorder
date: 2011-04-14T09:04:45Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0002573

optokinetic reflex
type: Class
subclass of: cranial nerve related reflex
definition: "A reflex allows the eye to follow objects in motion when the head remains stationary." [wikipedia:Optokinetic_reflex]
date: 2011-04-14T09:20:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

pilomotor reflex
type: Class
subclass of: reflexive behavior
definition: "A reflex that elucidates goose bumps (bumps on a person's skin at the base of body hairs) which may involuntarily develop when a person is cold or experiences strong emotions such as fear, awe, admiration or sexual arousal" [wikipedia:Goose_bumps]
date: 2011-04-14T10:15:17Z
created by: George Gkoutos
has exact synonym: horripilation
has exact synonym: piloerection
has OBO namespace: behavior_ontology

pinna reflex
type: Class
subclass of: reflexive behavior
definition: A reflex that elucidates a characteristic ear twitch in response to an auditory stimulus.
date: 2011-04-14T10:19:59Z
created by: George Gkoutos
has exact synonym: Preyer's reflex
has OBO namespace: behavior_ontology

Axiom
annotated source: pinna reflex
annotated property: definition
annotated target: A reflex that elucidates a characteristic ear twitch in response to an auditory stimulus.
source: NBO:GVG

postural reflex
type: Class
subclass of: reflexive behavior
definition: A reflex that maintains body position and equilibrium either during rest or during movement.
date: 2011-04-14T10:24:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: postural reflex
annotated property: definition
annotated target: A reflex that maintains body position and equilibrium either during rest or during movement.
source: NBO:GVG

righting reflex
type: Class
subclass of: postural reflex
definition: A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
date: 2011-04-14T10:28:56Z
created by: George Gkoutos
has exact synonym: righting response
has OBO namespace: behavior_ontology

Axiom
annotated source: righting reflex
annotated property: definition
annotated target: A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
source: NBO:GVG

hyperekplexia
type: Class
subclass of: reflexive behavior phenotype
definition: A pathological behavior characterised by pronounced startle responses to tactile or acoustic stimuli and hypertonia.
date: 2011-04-14T10:37:34Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hyperekplexia
annotated property: definition
annotated target: A pathological behavior characterised by pronounced startle responses to tactile or acoustic stimuli and hypertonia.
source: wikipedia:Hyperekplexia

tonic neck reflex
type: Class
subclass of: postural reflex
definition: "A reflex that elucidates an automatic positioning of the limbs in response to a movement of the head on trunk (neck)." [web:http\://www.dizziness-and-balance.com/anatomy/vspine.htm]
date: 2011-04-14T10:42:28Z
created by: George Gkoutos
has exact synonym: TNR
has exact synonym: cervicospinal reflex
has OBO namespace: behavior_ontology

vestibulocollic reflex
type: Class
subclass of: postural reflex
definition: A reflex which results from activation of afferents from the vestibular organs and uses neck movements to stabilize the head position in space.
date: 2011-04-14T10:44:18Z
created by: George Gkoutos
has exact synonym: VCR
has OBO namespace: behavior_ontology

Axiom
annotated source: vestibulocollic reflex
annotated property: definition
annotated target: A reflex which results from activation of afferents from the vestibular organs and uses neck movements to stabilize the head position in space.
source: JAX:

vestibulospinal reflex
type: Class
subclass of: postural reflex
definition: A reflex that originates with vestibular stimulation and control body posture.
date: 2011-04-14T10:47:03Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: vestibulospinal reflex
annotated property: definition
annotated target: A reflex that originates with vestibular stimulation and control body posture.
source: NBO:GVG

vibrissae reflex
type: Class
subclass of: reflexive behavior
definition: "Change position in response to stimulation of the whiskers." [JAX:<new dbxref>]
date: 2011-04-14T10:52:19Z
created by: George Gkoutos
has exact synonym: vibrissa reflex
has OBO namespace: behavior_ontology

clutching reflex
type: Class
subclass of: reflexive behavior
definition: A mouse reflex that elicidated the clasping of front and/or hind feet almost immediately upon being lifted by tail.
date: 2011-04-14T10:55:22Z
created by: George Gkoutos
has exact synonym: hindlimb extension reflex
has exact synonym: limb clasping
has exact synonym: limb grasping
has OBO namespace: behavior_ontology

Axiom
annotated source: clutching reflex
annotated property: definition
annotated target: A mouse reflex that elicidated the clasping of front and/or hind feet almost immediately upon being lifted by tail.
source: EUROPHENOME:

emprosthotonos
type: Class
subclass of: tetanic spasm
definition: A form of tetanic spasm in which the head and feet are drawn forward and the spine arches backward.
date: 2011-04-14T11:05:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0009354

Axiom
annotated source: emprosthotonos
annotated property: definition
annotated target: A form of tetanic spasm in which the head and feet are drawn forward and the spine arches backward.
source: JAX:

opisthotonus
type: Class
subclass of: tetanic spasm
definition: A form of tetanic spasm in which the head, neck and spine are bent backward and the body is bowed forward.
date: 2011-04-14T11:08:01Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002179
xref: MP:0002880

Axiom
annotated source: opisthotonus
annotated property: definition
annotated target: A form of tetanic spasm in which the head, neck and spine are bent backward and the body is bowed forward.
source: JAX:

tetanic spasm
type: Class
subclass of: spasm
definition: A sudden, involuntary contraction of a muscle or group of muscles associated with strychnine poisoning and tetanus.
date: 2011-04-14T11:09:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: tetanic spasm
annotated property: definition
annotated target: A sudden, involuntary contraction of a muscle or group of muscles associated with strychnine poisoning and tetanus.
source: NBO:GVG

spasm
type: Class
subclass of: involuntary movement behavior phenotype
definition: A sudden, involuntary contraction of a muscle or group of muscles.
date: 2011-04-14T11:10:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: spasm
annotated property: definition
annotated target: A sudden, involuntary contraction of a muscle or group of muscles.
source: NBO:GVG

tremor
type: Class
subclass of: involuntary movement behavior phenotype
definition: An involuntary rhythmical, oscillatory movement of a body part.
date: 2011-04-14T11:13:39Z
created by: George Gkoutos
has exact synonym: quivering
has exact synonym: shivering
has exact synonym: trembling
has OBO namespace: behavior_ontology
xref: HP:0001337
xref: MP:0000745

Axiom
annotated source: tremor
annotated property: definition
annotated target: An involuntary rhythmical, oscillatory movement of a body part.
source: NBO:GVG

ataxia
type: Class
subclass of: motor coordination phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: motor coordination
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000770
definition: Inability to coordinate voluntary muscular movements.
date: 2011-04-14T11:25:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0001251
xref: MP:0001393

Axiom
annotated source: ataxia
annotated property: definition
annotated target: Inability to coordinate voluntary muscular movements.
source: NBO:GVG

motor coordination phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: motor coordination
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: vestibular behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: motor coordination
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the coordination of combinations of body movements created with the kinematic (such as spatial direction) and kinetic (force) parameters that result in intended actions.
date: 2011-04-14T11:32:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: motor coordination phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the coordination of combinations of body movements created with the kinematic (such as spatial direction) and kinetic (force) parameters that result in intended actions.
source: NBO:GVG

dysmetria
type: Class
subclass of: motor coordination phenotype
definition: Lack of coordination of movement typified by the undershoot or overshoot of intended position with the hand, arm, leg, or eye.
date: 2011-04-14T11:33:13Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0003314

Axiom
annotated source: dysmetria
annotated property: definition
annotated target: Lack of coordination of movement typified by the undershoot or overshoot of intended position with the hand, arm, leg, or eye.
source: wikipedia:Dysmetria

hypermetria
type: Class
subclass of: dysmetria
definition: Overshooting the intended position.
date: 2011-04-14T11:34:23Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hypermetria
annotated property: definition
annotated target: Overshooting the intended position.
source: wikipedia:Dysmetria

hypometria
type: Class
subclass of: dysmetria
definition: Undershooting the intended position.
date: 2011-04-14T11:34:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hypometria
annotated property: definition
annotated target: Undershooting the intended position.
source: wikipedia:Dysmetria

posture phenotype
type: Class
subclass of: vestibular behavior phenotype
definition: Observable characteristic of behavior related with the Intentionally or habitually assumed arrangement of the body and its limbs.
date: 2011-04-14T11:37:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: posture phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related with the Intentionally or habitually assumed arrangement of the body and its limbs.
source: NBO:GVG

titubation
type: Class
subclass of: posture phenotype
definition: "Posture distinguished by a faltering gait while walking and/or a swaying motion of the trunk or head while resting." [JAX:<new dbxref>]
date: 2011-04-14T11:37:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0009514

hindlimb paralysis
type: Class
subclass of: paralysis
definition: Loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply.
date: 2011-04-14T01:20:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0000755

Axiom
annotated source: hindlimb paralysis
annotated property: definition
annotated target: Loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply.
source: JAX:

dystonia
type: Class
subclass of: locomotory behavior phenotype
definition: A locomotory disorder in which sustained muscle contractions cause twisting and repetitive movements or abnormal postures.
date: 2011-04-14T01:24:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0001332
xref: MP:0005323

Axiom
annotated source: dystonia
annotated property: definition
annotated target: A locomotory disorder in which sustained muscle contractions cause twisting and repetitive movements or abnormal postures.
source: wikipedia:Dystonia

long-term spatial memory
type: Class
subclass of: spatial memory
definition: A type of memory that allows one to store and manage information about one's environment and its spatial orientation lasting hours to months.
date: 2011-04-14T01:43:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: long-term spatial memory
annotated property: definition
annotated target: A type of memory that allows one to store and manage information about one's environment and its spatial orientation lasting hours to months.
source: NBO:GVG

psychomotor agitation behavior
type: Class
subclass of: agitation behavior
definition: "Agitation characterised by a series of unintentional and purposeless motions that stem from mental tension and anxiety of an individual." [wikipedia:Psychomotor_agitation]
date: 2011-04-14T03:03:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

emotional behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: emotional behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: emotional behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences.
date: 2011-04-14T03:07:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: emotional behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences.
source: NBO:GVG

apathy
type: Class
subclass of: emotional behavior phenotype
definition: "Exhibiting indifference, or suppression of emotions such as concern, excitement, motivation and passion." [wikipedia:Indifference_(emotion)]
date: 2011-04-14T03:07:51Z
created by: George Gkoutos
has exact synonym: impassivity
has exact synonym: perfunctoriness
has OBO namespace: behavior_ontology
xref: HP:0000741

delusion
type: Class
subclass of: cognitive behavior phenotype
definition: A belief that is either mistaken or not substantiated that is held with vehemence.
date: 2011-04-14T03:20:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000746

Axiom
annotated source: delusion
annotated property: definition
annotated target: A belief that is either mistaken or not substantiated that is held with vehemence.
source: wikipedia:Delusion

social inhibition
type: Class
subclass of: social behavior
definition: "A social behavior characterised by conscious or unconscious constraint of a behavior that might be considered objectionable in a social setting." [wikipedia:Social_inhibition]
date: 2011-04-14T03:33:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

sexual inhibition
type: Class
subclass of: social behavior
definition: "A social behavior characterised by conscious or unconscious constraint or curtailment of behavior relating to specific sexual matters or practices." [wikipedia:Sexual_inhibition]
date: 2011-04-14T03:34:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

forgetfulness
type: Class
equivalent class: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0002361
    intersection of: Restriction
      on property: towards
      some values from: memory loss behavior
subclass of: cognitive behavior phenotype
subclass of: Restriction
  on property: has quality
  some values from: Class
    intersection of: PATO_0002361
    intersection of: Restriction
      on property: towards
      some values from: memory loss behavior
definition: Loss of information already encoded and stored in an individual's long term memory.
date: 2011-04-14T03:42:46Z
created by: George Gkoutos
has exact synonym: pathological forgetting
has exact synonym: retention loss
has OBO namespace: behavior_ontology
xref: HP:0000747

Axiom
annotated source: forgetfulness
annotated property: definition
annotated target: Loss of information already encoded and stored in an individual's long term memory.
source: wikipedia:Forgetting

cognitive behavior
type: Class
subclass of: behavior process
definition: Behaviour related to cognitive processes.
date: 2011-04-14T03:51:13Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cognitive behavior
annotated property: definition
annotated target: Behaviour related to cognitive processes.
source: NBO:JH

hallucination
type: Class
subclass of: sensation behavior
definition: Perception in the absence of a stimulus.
date: 2011-04-14T03:52:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0000738

Axiom
annotated source: hallucination
annotated property: definition
annotated target: Perception in the absence of a stimulus.
source: wikipedia:Hallucination

visual hallucination
type: Class
equivalent class: Class
  intersection of: hallucination
  intersection of: Restriction
    on property: by_means
    some values from: UBERON_0002104
subclass of: hallucination
subclass of: Restriction
  on property: by_means
  some values from: UBERON_0002104
definition: A form of hallucination that involves perceiving images without visual stimulus.
date: 2011-04-14T03:54:02Z
created by: George Gkoutos
has exact synonym: paracusia
has OBO namespace: behavior_ontology
xref: HP:0008765

Axiom
annotated source: visual hallucination
annotated property: definition
annotated target: A form of hallucination that involves perceiving images without visual stimulus.
source: NBO:GVG

auditory hallucination
type: Class
equivalent class: Class
  intersection of: hallucination
  intersection of: Restriction
    on property: by_means
    some values from: UBERON_0002105
subclass of: hallucination
subclass of: Restriction
  on property: by_means
  some values from: UBERON_0002105
definition: "A form of hallucination that involves perceiving sounds without auditory stimulus." [wikipedia:Auditory_hallucination]
date: 2011-04-14T03:56:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002367

olfactory hallucination
type: Class
equivalent class: Class
  intersection of: hallucination
  intersection of: Restriction
    on property: by_means
    some values from: UBERON_0005725
subclass of: hallucination
subclass of: Restriction
  on property: by_means
  some values from: UBERON_0005725
definition: A form of hallucination that involves perceiving odors without odor stimulus.
date: 2011-04-14T03:58:15Z
created by: George Gkoutos
has exact synonym: phantosmia
has OBO namespace: behavior_ontology

Axiom
annotated source: olfactory hallucination
annotated property: definition
annotated target: A form of hallucination that involves perceiving odors without odor stimulus.
source: NBO:GVG

communication behavior
type: Class
subclass of: social behavior
definition: A social behavior related to the activity of conveying information.
date: 2011-04-14T04:39:42Z
created by: George Gkoutos
has exact synonym: communicating
has narrow synonym: signal exchange
has OBO namespace: behavior_ontology

Axiom
annotated source: communication behavior
annotated property: definition
annotated target: A social behavior related to the activity of conveying information.
source: wikipedia:Communication

nonverbal communication behavior
type: Class
subclass of: communication behavior
definition: "Communication behavior related to the process of conveying meaning in the form of non-word messages through for example gesture, body language or posture; facial expression and eye contact etc." [wikipedia:.wikipedia.org/wiki/Nonverbal_communication]
date: 2011-04-14T04:40:59Z
created by: George Gkoutos
has exact synonym: non-verbal communication behaviour
has exact synonym: nonverbal communication behaviour
has OBO namespace: behavior_ontology

visual communication behavior
type: Class
subclass of: communication behavior
definition: "Communication behavior related to the conveyance of ideas and information through creation of visual representations." [wikipedia:Visual_communication]
date: 2011-04-14T04:42:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

oral communication behavior
type: Class
subclass of: communication behavior
definition: "Communication behavior related to the process of conveying meaning in the form of word messages." [wikipedia:Oral_communication#Oral_communication]
date: 2011-04-14T04:44:04Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

eye contact
type: Class
subclass of: nonverbal communication behavior
definition: "A nonverbal communication behavior that is characterised by the meeting the eyes between two individuals." [wikipedia:Eye_contact]
date: 2011-04-14T04:46:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

laughing behavior
type: Class
subclass of: emotional behavior
date: 2011-04-14T04:51:05Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

crying behavior
type: Class
subclass of: emotional behavior
definition: The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
date: 2011-04-14T04:52:56Z
created by: George Gkoutos
has exact synonym: crying behaviour
has OBO namespace: behavior_ontology
xref: GO:0060273

Axiom
annotated source: crying behavior
annotated property: definition
annotated target: The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
source: NBO:GVG

behavior stemming from insight
type: Class
subclass of: behavior stemming from intelligence
definition: Behavior stemming from understanding of a specific cause and effect in a specific context.
date: 2011-04-14T04:57:19Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavior stemming from insight
annotated property: definition
annotated target: Behavior stemming from understanding of a specific cause and effect in a specific context.
source: wikipedia:Insight

frustration behavior
type: Class
subclass of: emotional behavior
definition: An emotional behavior that arises from the perceived resistance to the fulfillment of individual will.
date: 2011-04-14T05:00:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: frustration behavior
annotated property: definition
annotated target: An emotional behavior that arises from the perceived resistance to the fulfillment of individual will.
source: wikipedia:Frustration

selective mutism
type: Class
subclass of: social behavior phenotype
definition: "A communication disorder in which a person, most often a child, who is normally capable of speech is unable to speak in given situations, or to specific people." [wikipedia:Selective_mutism]
date: 2011-04-14T05:06:03Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002300

stereotypic motor behavior
type: Class
subclass of: stereotypic behavior
definition: Any highly repetitive behavior, where the repetition is unusual, difficult to disrupt, and neither the behavior nor repetition serve an obvious function [NBO:AC]
date: 2011-04-14T05:18:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0008758

echolalia
type: Class
subclass of: stereotypic behavior
definition: Stereotypic behavior characterised by a tendency to repeat vocalizations.
date: 2011-04-14T05:20:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0010529

Axiom
annotated source: echolalia
annotated property: definition
annotated target: Stereotypic behavior characterised by a tendency to repeat vocalizations.
source: NBO:GVG

object play
type: Class
subclass of: playing behavior
definition: Play behavior associated with the manipulation of objects.
date: 2011-04-19T10:51:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Object play is important in developing skills important in adulthood, especially hunting.

Axiom
annotated source: object play
annotated property: definition
annotated target: Play behavior associated with the manipulation of objects.
source: NBO:GVG

sexual play
type: Class
subclass of: social play
definition: "Behavior associated with interactions which resemble sexual behavior but do not lead to copulation." [web:http\://www.bio.davidson.edu/people/vecase/behavior/Spring2009/Sacco/Pages/Sex%20Play.html]
date: 2011-04-19T10:52:50Z
created by: George Gkoutos
has exact synonym: love play
has OBO namespace: behavior_ontology

play fight
type: Class
subclass of: social play
definition: "Play behavior associated to fighting simulation, although fighting is much slower and gentler with no intention of actual hurt." [web:http\://www.bio.davidson.edu/people/vecase/behavior/Spring2009/Sacco/Pages/Play%20Fighting.html]
date: 2011-04-19T10:53:55Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Play fighting helps learning to evaluate oneself and an opponent. This skill is crucial for serious adult situations. Being able to size up an opponent quickly is very important in knowing when to give up or fight for a resource (food, mate, territory, etc. ). Play fighting is one of the most important categories of play because it prepares animals for actual fighting.

play chasing
type: Class
subclass of: social play
definition: Play behavior that is associated with the pursuit of an individual.
date: 2011-04-19T10:54:09Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: play chasing
annotated property: definition
annotated target: Play behavior that is associated with the pursuit of an individual.
source: NBO:GVG

nursing play
type: Class
subclass of: social play
definition: Play behavior associated with the exhibition of parenting behavior by non-parents.
date: 2011-04-19T11:03:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: nursing play
annotated property: definition
annotated target: Play behavior associated with the exhibition of parenting behavior by non-parents.
source: NBO:GVG

imitative play
type: Class
subclass of: playing behavior
definition: "Play behavior related to the copying the actions of another." [web:http\://www.bio.davidson.edu/people/vecase/behavior/Spring2009/Sacco/Pages/Imitative%20Play.html]
date: 2011-04-19T11:07:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Imitative play is an excellent means of learning how to perform a task that an adult has perfected. Therefore, imitative play is one of the best ways for animals to learn from the adults in the group.

mobbing behavior
type: Class
subclass of: antipredation behavior
subclass of: aggressive behavior by means
definition: Harassment of and-or attack of a presumed predator or intruder by multiple individuals at once [NBO:SMAC]
date: 2011-04-19T01:44:21Z
created by: George Gkoutos
has exact synonym: mobbing
has OBO namespace: behavior_ontology

mobbing calling
type: Class
subclass of: behavioral control of production of sound
subclass of: mobbing behavior
definition: "Behavior associated with signals made by the mobbing species while harassing a predator." [wikipedia:Mobbing_(animal_behavior)]
date: 2011-04-19T01:46:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

territorial aggressive behavior
type: Class
subclass of: aggressive behavior towards animals
definition: Aggressive behavior related to the defence of a fixed area against intruders, typically conspecifics.
date: 2011-04-19T02:02:11Z
created by: George Gkoutos
has exact synonym: territorial aggression
has exact synonym: territorial aggressive behaviour
has OBO namespace: behavior_ontology
xref: GO:0002124

Axiom
annotated source: territorial aggressive behavior
annotated property: definition
annotated target: Aggressive behavior related to the defence of a fixed area against intruders, typically conspecifics.
source: GOC:hjd

irritable aggressive behavior
type: Class
equivalent class: Class
  intersection of: aggressive behavior
  intersection of: Restriction
    on property: by_means
    some values from: irritability behavior
subclass of: aggressive behavior
subclass of: aggressive behavior by means
subclass of: Restriction
  on property: by_means
  some values from: irritability behavior
date: 2011-04-19T02:05:35Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

avoidance behavior
type: Class
subclass of: motivation behavior
definition: "Behavior related to the activity seen in animals exposed to adverse stimuli, in which the tendency to act defensively is stronger than the tendency to attack." [web:http\://www.britannica.com/EBchecked/topic/45916/avoidance-behavior]
date: 2011-04-19T03:36:00Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

protective behavior
type: Class
subclass of: avoidance behavior
definition: Behavior related to the activity seen in animals exposed to potential danger in which they exhibit the tendency to act defensively.
date: 2011-04-19T03:49:55Z
created by: George Gkoutos
has exact synonym: defense
has exact synonym: defensive behaviour
has OBO namespace: behavior_ontology

Axiom
annotated source: protective behavior
annotated property: definition
annotated target: Behavior related to the activity seen in animals exposed to potential danger in which they exhibit the tendency to act defensively.
source: NBO:SD

male courtship behavior
type: Class
subclass of: courtship behavior
definition: The actions or reactions of a male, for the purpose of attracting a sexual partner.
date: 2011-04-21T08:40:33Z
created by: George Gkoutos
has exact synonym: male courtship behaviour
has OBO namespace: behavior_ontology
xref: GO:0008049

Axiom
annotated source: male courtship behavior
annotated property: definition
annotated target: The actions or reactions of a male, for the purpose of attracting a sexual partner.
source: GOC:bf

female courtship behavior
type: Class
subclass of: courtship behavior
definition: The actions or reactions of a female, for the purpose of attracting a sexual partner.
date: 2011-04-21T08:42:23Z
created by: George Gkoutos
has exact synonym: female courtship behaviour
has OBO namespace: behavior_ontology
xref: GO:0008050

Axiom
annotated source: female courtship behavior
annotated property: definition
annotated target: The actions or reactions of a female, for the purpose of attracting a sexual partner.
source: GOC:bf

long term thirst regulation
type: Class
subclass of: thirst motivation behavior
definition: Any process which modulates the physical craving for water over long term water deprivation.
date: 2011-04-21T09:06:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: long term thirst regulation
annotated property: definition
annotated target: Any process which modulates the physical craving for water over long term water deprivation.
source: NBO:GVG

short term thirst regulation
type: Class
subclass of: thirst motivation behavior
definition: Any process which modulates the physical craving for water over short term water deprivation.
date: 2011-04-21T09:06:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: short term thirst regulation
annotated property: definition
annotated target: Any process which modulates the physical craving for water over short term water deprivation.
source: NBO:GVG

discrimination learning
type: Class
subclass of: associative learning behavior
date: 2011-05-06T03:56:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

epilepsy
type: Class
subclass of: seizures/epilepsy
definition: Two or more unprovoked recurrent seizures.
date: 2011-05-27T11:42:33Z
created by: George Gkoutos
has exact synonym: unprovoked seizure
has OBO namespace: behavior_ontology
xref: HP:0001275

Axiom
annotated source: epilepsy
annotated property: definition
annotated target: Two or more unprovoked recurrent seizures.
source: NBO:GVG

involuntary movement behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: involuntary movement behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: kinesthetic behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: involuntary movement behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to movements that occur independent of planning.
date: 2011-05-27T11:56:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: involuntary movement behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to movements that occur independent of planning.
source: NBO:GVG

voluntary movement behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: voluntary movement behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: kinesthetic behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: voluntary movement behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to movements executed with intent.
date: 2011-05-27T11:57:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: voluntary movement behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to movements executed with intent.
source: NBO:GVG

convulsion
type: Class
subclass of: involuntary movement behavior phenotype
definition: A rapid and repeated body muscle contract that results in an uncontrolled shaking of the body.
date: 2011-05-27T11:59:40Z
created by: George Gkoutos
has exact synonym: fit
has OBO namespace: behavior_ontology

Axiom
annotated source: convulsion
annotated property: definition
annotated target: A rapid and repeated body muscle contract that results in an uncontrolled shaking of the body.
source: NBO:GVG

partial seizure
type: Class
subclass of: seizures
definition: "A seizure which affect only a part of the brain at onset." [wikipedia:http\://en.wikipedia.org/wiki/Focal_seizures]
date: 2011-05-27T12:49:09Z
created by: George Gkoutos
has exact synonym: focal seizure
has exact synonym: localized seizure
has OBO namespace: behavior_ontology
xref: HP:0007359
comment: Partial seizures begin with an electrical discharge in one limited area of the brain.

simple partial seizure
type: Class
subclass of: partial seizure
definition: "A partial seizure which affect only a small region of the brain, often the temporal lobes and/or hippocampi whilst consciousness is unaffected." [wikipedia:http\://en.wikipedia.org/wiki/Simple_partial_seizure]
date: 2011-05-27T12:51:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002349
comment: Depending on the area of cerebral cortex involved, symptoms may be motor, cognitive, sensory, autonomic, or affective. Consciousness is not impaired.

complex partial seizure
type: Class
subclass of: partial seizure
definition: "A seizure that is associated with bilateral cerebral hemisphere involvement and causes impairment of awareness or responsiveness, i.e. loss of consciousness." [wikipedia:http\://en.wikipedia.org/wiki/Complex_partial_seizures]
date: 2011-05-27T12:59:01Z
created by: George Gkoutos
has exact synonym: psychomotor seizure
has exact synonym: temporal lobe seizure
has OBO namespace: behavior_ontology
xref: HP:0002384
xref: MP:0002195

being conscious
type: Class
subclass of: consciousness behavior
date: 2011-05-27T01:51:38Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

temporal lobe epilepsy
type: Class
subclass of: epilepsy
definition: "A type of focal epilepsy characterized by recurrent seizures." [NBO:http\://en.wikipedia.org/wiki/Temporal_lobe_epilepsy]
date: 2011-05-27T02:42:59Z
created by: George Gkoutos
has exact synonym: psychomotor epilepsy
has OBO namespace: behavior_ontology

simple partial seizure with motor signs
type: Class
subclass of: simple partial seizure
definition: A simple partial seizure affecting the kinesthetic behavior.
date: 2011-05-27T02:50:59Z
created by: George Gkoutos
has exact synonym: focal clonic seizure
has exact synonym: motor seizure
has OBO namespace: behavior_ontology
xref: HP:0002266

Axiom
annotated source: simple partial seizure with motor signs
annotated property: definition
annotated target: A simple partial seizure affecting the kinesthetic behavior.
source: NBO:GVG

simple partial seizure with sensory symptoms
type: Class
subclass of: simple partial seizure
definition: A simple partial seizure affecting any of the five senses -- vision, touch, smell, taste, and hearing.
date: 2011-05-27T02:51:16Z
created by: George Gkoutos
has exact synonym: Jacksonian sensory seizure
has exact synonym: sensory seizure
has OBO namespace: behavior_ontology
comment: Some simple partial seizures consist of a sensory experience. The person may see lights, hear a buzzing sound, or feel tingling or numbness in a part of the body.

Axiom
annotated source: simple partial seizure with sensory symptoms
annotated property: definition
annotated target: A simple partial seizure affecting any of the five senses -- vision, touch, smell, taste, and hearing.
source: NBO:GVG

simple partial seizure with autonomic symptoms or signs
type: Class
subclass of: simple partial seizure
definition: A simple partial seizure affecting the part of the nervous system that automatically controls bodily functions.
date: 2011-05-27T02:51:31Z
created by: George Gkoutos
has exact synonym: abdominal epilepsy
has exact synonym: autonomic seizure
has OBO namespace: behavior_ontology
comment: These seizures are accompanied by autonomic symptoms or signs, such as abdominal discomfort or nausea which may rise into the throat (epigastric rising), stomach pain, the rumbling sounds of gas moving in the intestines (borborygmi), belching, flatulence and vomiting. Other symptoms may include pallor, flushing, sweating, hair standing on end (piloerection), dilation of the pupils, alterations in heart rate and respiration, and urination. A few people may experience sexual arousal, penile erection, and orgasm.

Axiom
annotated source: simple partial seizure with autonomic symptoms or signs
annotated property: definition
annotated target: A simple partial seizure affecting the part of the nervous system that automatically controls bodily functions.
source: NBO:GVG

simple partial seizure with psychic symptoms
type: Class
subclass of: simple partial seizure
definition: A simple partial seizure affecting the emotional behavior.
date: 2011-05-27T02:51:48Z
created by: George Gkoutos
has exact synonym: psychic seizure
has exact synonym: simple partial seizures of temporal lobe origin
has exact synonym: temporal lobe auras
has OBO namespace: behavior_ontology
comment: Simple partial seizures which arise in or near the temporal lobes often take the form of an odd experience. One may see or hear things that are not there. One feels emotions, often fear, but sometimes sadness, anger, or joy. There may be a bad smell or a bad taste, a funny feeling in the pit of the stomach or a choking sensation.

Axiom
annotated source: simple partial seizure with psychic symptoms
annotated property: definition
annotated target: A simple partial seizure affecting the emotional behavior.
source: NBO:GVG

sensation behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sensation behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: cognitive behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sensation behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related any of the five senses -- vision, touch, smell, taste, and hearing.
date: 2011-05-27T03:06:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sensation behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related any of the five senses -- vision, touch, smell, taste, and hearing.
source: NBO:GVG

somatic sensation related behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: somatic sensation related behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sensation behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: somatic sensation related behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: A phenotype manifested by a behavior related to the sensations arising from the skin and from the muscles, tendons, and joints.
date: 2011-05-27T03:20:39Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: somatic sensation related behavior phenotype
annotated property: definition
annotated target: A phenotype manifested by a behavior related to the sensations arising from the skin and from the muscles, tendons, and joints.
source: NBO:GVG

cutaneous sensation behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: cutaneous sensation behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: somatic sensation related behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: cutaneous sensation behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2011-05-27T03:21:20Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

auditory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: auditory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sensation behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: auditory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the actions or reactions of an organism in response to a sound.
date: 2011-05-27T03:22:16Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: auditory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the actions or reactions of an organism in response to a sound.
source: NBO:GVG

visual behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: visual behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sensation behavior phenotype
subclass of: reproductive behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: visual behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: A phenotype manifested by a behavior related to the actions or reactions of an organism in response to a visual stimulus.
date: 2011-05-27T03:22:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: visual behavior phenotype
annotated property: definition
annotated target: A phenotype manifested by a behavior related to the actions or reactions of an organism in response to a visual stimulus.
source: NBO:GVG

chemosensory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: chemosensory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sensation behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: chemosensory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the sensation of chemicals.
date: 2011-05-27T03:26:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: chemosensory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the sensation of chemicals.
source: NBO:GVG

olfactory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: olfactory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: chemosensory behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: olfactory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the sensation of odors.
date: 2011-05-27T03:28:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: olfactory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the sensation of odors.
source: NBO:GVG

generalized seizure
type: Class
subclass of: seizures
definition: A seizure which affect the whole of the brain at onset.
date: 2011-05-27T03:46:46Z
created by: George Gkoutos
has exact synonym: primarily generalized seizure
has OBO namespace: behavior_ontology
xref: HP:0002197
comment: Primary generalized seizures begin with a widespread electrical discharge that involves both sides of the brain at once.

Axiom
annotated source: generalized seizure
annotated property: definition
annotated target: A seizure which affect the whole of the brain at onset.
source: NBO:GVG

partial seizure evolving to secondarily generalized seizure
type: Class
subclass of: partial seizure
date: 2011-05-27T03:49:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0007334

simple partial seizure evolving to generalized seizure
type: Class
subclass of: partial seizure evolving to secondarily generalized seizure
date: 2011-05-27T03:50:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

complex partial seizure evolving to generalized seizure
type: Class
subclass of: partial seizure evolving to secondarily generalized seizure
date: 2011-05-27T03:50:26Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

simple partial seizure evolving to complex partial seizure evolving to generalized seizure
type: Class
subclass of: partial seizure evolving to secondarily generalized seizure
date: 2011-05-27T03:50:49Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

simple partial onset, followed by impairment of consciousness
type: Class
subclass of: complex partial seizure
date: 2011-05-27T03:51:50Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

with impairment of consciousness at onset
type: Class
subclass of: complex partial seizure
date: 2011-05-27T03:52:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

absence seizures
type: Class
subclass of: generalized seizure
definition: "An absence seizure is a brief (usually less that 20 seconds), generalized epileptic seizure of sudden onset and termination." [wikipedia:http\://en.wikipedia.org/wiki/Absence_seizure]
date: 2011-05-27T03:54:48Z
created by: George Gkoutos
has exact synonym: petit mal seizure
has OBO namespace: behavior_ontology
xref: HP:0002121
xref: MP:0003216

atonic seizure
type: Class
subclass of: generalized seizure
definition: "A type of generalized seizure that consist of a brief lapse in muscle tone that are caused by temporary alterations in brain function." [wikipedia:http\://en.wikipedia.org/wiki/Atonic_seizure]
date: 2011-05-27T03:57:35Z
created by: George Gkoutos
has exact synonym: akinetic seizure
has exact synonym: drop attack
has exact synonym: drop seizure
has OBO namespace: behavior_ontology
xref: HP:0010819

myoclonic seizure
type: Class
subclass of: generalized seizure
definition: A type of seizure that is characterised by a very brief symmetric alternating contraction and relaxation of a muscle or a group of muscles.
date: 2011-05-27T04:52:23Z
created by: George Gkoutos
has exact synonym: myoclonus
has OBO namespace: behavior_ontology
xref: HP:0001336
xref: HP:0002123
xref: MP:0000243
comment: Symmetric jerking of the extremities.

Axiom
annotated source: myoclonic seizure
annotated property: definition
annotated target: A type of seizure that is characterised by a very brief symmetric alternating contraction and relaxation of a muscle or a group of muscles.
source: NBO:GVG

clonic seizure
type: Class
subclass of: generalized seizure
definition: A type of seizure that is characterised by rhythmic symmetric alternating contraction and relaxation of a muscle or a group of muscles.
date: 2011-05-27T04:54:59Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: MP:0003996
comment: Rapid, repetitive motor activity.

Axiom
annotated source: clonic seizure
annotated property: definition
annotated target: A type of seizure that is characterised by rhythmic symmetric alternating contraction and relaxation of a muscle or a group of muscles.
source: NBO:GVG

juvenile myoclonic epilepsy
type: Class
subclass of: myoclonic epilepsy
definition: A type of epilepsy characterised by myoclonic seizures usually involving the neck, shoulders, and upper arms.
date: 2011-05-27T04:55:32Z
created by: George Gkoutos
has exact synonym: Janz syndrome
has OBO namespace: behavior_ontology

Axiom
annotated source: juvenile myoclonic epilepsy
annotated property: definition
annotated target: A type of epilepsy characterised by myoclonic seizures usually involving the neck, shoulders, and upper arms.
source: NBO:GVG

Lennox-Gastaut syndrome
type: Class
subclass of: epilepsy
definition: A type of epilepsy characterised by multiple different types of seizures, particularly including tonic (stiffening) and atonic (drop) types of seizures.
date: 2011-05-27T04:56:28Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: Lennox-Gastaut syndrome
annotated property: definition
annotated target: A type of epilepsy characterised by multiple different types of seizures, particularly including tonic (stiffening) and atonic (drop) types of seizures.
source: NBO:GVG

reflex seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure generated by sudden sensor stimulation caused by the environment.
date: 2011-05-28T11:07:41Z
created by: George Gkoutos
has exact synonym: environmental epilepsy
has exact synonym: reflex epilepsy
has OBO namespace: behavior_ontology
xref: MP:0009358

Axiom
annotated source: reflex seizure
annotated property: definition
annotated target: A type of seizure generated by sudden sensor stimulation caused by the environment.
source: NBO:GVG

tonic clonic seizure
type: Class
subclass of: generalized seizure
definition: A type of generalized seizure characterised by a combination of tonic stiffening (extensions) followed by clonic flexion motions.
date: 2011-05-27T05:03:11Z
created by: George Gkoutos
has exact synonym: gran mal seizure
has exact synonym: grand mal seizure
has OBO namespace: behavior_ontology
xref: HP:0002069
xref: MP:0003997
comment: The seizures are divided into two phases, the tonic phase and the clonic phase, hence the name of the seizure, though a tonic clonic seizure will often be preceded by an aura.

Axiom
annotated source: tonic clonic seizure
annotated property: definition
annotated target: A type of generalized seizure characterised by a combination of tonic stiffening (extensions) followed by clonic flexion motions.
source: NBO:GVG

tonic seizure
type: Class
subclass of: generalized seizure
definition: A type of seizure characterised by muscle rigidity.
date: 2011-05-27T05:09:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0010818
xref: MP:0002826

Axiom
annotated source: tonic seizure
annotated property: definition
annotated target: A type of seizure characterised by muscle rigidity.
source: NBO:GVG

febrile seizure
type: Class
subclass of: provoked seizure
definition: "A type of seizure associated with a significant rise in body temperature." [wikpedia:http\://en.wikipedia.org/wiki/Febrile_seizure]
date: 2011-05-27T05:13:26Z
created by: George Gkoutos
has exact synonym: febrile convulsion
has exact synonym: fever fit
has OBO namespace: behavior_ontology
xref: HP:0002373

simple febrile seizure
type: Class
subclass of: febrile seizure
definition: "A febrile seizure that lasts less than 15 minutes , does not recur in 24 hours, and involves the entire body." [wikipedia:http\://en.wikipedia.org/wiki/Febrile_seizure]
date: 2011-05-27T05:16:07Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

complex febrile seizure
type: Class
subclass of: febrile seizure
definition: "A febrile seizure characterized by longer duration, recurrence, or focus on only part of the body." [wikipedia:http\://en.wikipedia.org/wiki/Febrile_seizure]
date: 2011-05-27T05:19:54Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

benign rolandic epilepsy
type: Class
subclass of: epilepsy
definition: "Benign rolandic epilepsy is characterized by either simple partial seizures involving the mouth and face or generalized tonic-clonic seizures." [wikipedia:http\://en.wikipedia.org/wiki/Rolandic_epilepsy]
date: 2011-05-27T05:24:49Z
created by: George Gkoutos
has exact synonym: benign (childhood) epilepsy with centrotemporal (EEG) spikes
has OBO namespace: behavior_ontology

medial temporal lobe epilepsy
type: Class
subclass of: temporal lobe epilepsy
definition: "A temporal lobe epilepsy arises in the hippocampus, parahippocampal gyrus and amygdala which are located in the inner aspect of the temporal lobe." [wikipedia:http\://en.wikipedia.org/wiki/Temporal_lobe_epilepsy]
date: 2011-05-27T05:30:25Z
created by: George Gkoutos
has exact synonym: MTLE
has OBO namespace: behavior_ontology

lateral temporal lobe epilepsy
type: Class
subclass of: temporal lobe epilepsy
definition: "A temporal lobe epilepsy arises in the neocortex on the outer surface of the temporal lobe of the brain." [wikipedia:http\://en.wikipedia.org/wiki/Temporal_lobe_epilepsy]
date: 2011-05-27T05:31:27Z
created by: George Gkoutos
has exact synonym: LTLE
has OBO namespace: behavior_ontology

childhood absence epilepsy
type: Class
subclass of: epilepsy
date: 2011-05-27T05:32:59Z
created by: George Gkoutos
has exact synonym: pyknolepsy
has OBO namespace: behavior_ontology

continuous seizure
type: Class
subclass of: seizures
date: 2011-05-27T05:39:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

provoked seizure
type: Class
subclass of: seizures/epilepsy
definition: "Paroxysmal events that mimic an epileptic seizure but do not involve abnormal, rhythmic discharges of cortical neurons." [wikipedia:http\://en.wikipedia.org/wiki/Non-epileptic_seizure]
date: 2011-05-27T05:47:13Z
created by: George Gkoutos
has exact synonym: non-epileptic seizure
has OBO namespace: behavior_ontology

psychogenic non-epileptic seizure
type: Class
subclass of: provoked seizure
definition: "A type of seizure of psychological origin that superficially resembles an epileptic seizure, but without the characteristic electrical discharges associated with epilepsy." [wikipedia:http\://en.wikipedia.org/wiki/Psychogenic_non-epileptic_seizures]
date: 2011-05-27T05:50:08Z
created by: George Gkoutos
has exact synonym: PNES
has exact synonym: non-epileptic attack disorder
has OBO namespace: behavior_ontology

myoclonic epilepsy
type: Class
subclass of: epilepsy
definition: A type of epilepsy that is characterised by myoclonic seizures.
date: 2011-05-27T05:53:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: myoclonic epilepsy
annotated property: definition
annotated target: A type of epilepsy that is characterised by myoclonic seizures.
source: NBO:GVG

progressive myoclonic epilepsy
type: Class
subclass of: myoclonic epilepsy
definition: "A myoclonic epilepsy characterised by a combination of myoclonic and tonic-clonic seizures." [wikipedia:http\://en.wikipedia.org/wiki/Progressive_myoclonic_epilepsy]
date: 2011-05-27T05:55:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

status epilepticus
type: Class
subclass of: epilepsy
definition: "Continuous unremitting seizure lasting longer than 30 minutes or recurrent seizures without regaining consciousness between seizures for greater than 30 minutes." [wikipedia:http\://en.wikipedia.org/wiki/Status_epilepticus]
date: 2011-05-27T05:59:47Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002133

non-convulsive status epilepticus
type: Class
subclass of: status epilepticus
date: 2011-05-27T06:42:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

generalised convulsive status epilepticus
type: Class
subclass of: status epilepticus
date: 2011-05-27T06:42:29Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

complex partial status epilepticus
type: Class
subclass of: non-convulsive status epilepticus
definition: "A convulsive status epilepticus characterized by seizures involving long-lasting stupor, staring and unresponsiveness." [wikipedia:http\://en.wikipedia.org/wiki/Complex_partial_status_epilepticus]
date: 2011-05-27T07:20:21Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

absence status epilepticus
type: Class
subclass of: non-convulsive status epilepticus
date: 2011-05-27T07:21:27Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

subtle status epilepticus
type: Class
subclass of: status epilepticus
definition: "Subtle status epilepticus consists of electrical seizure activity in the brain that endures when the associated motor responses are fragmentary or even absent." [web:http\://emedicine.medscape.com/article/1164462-overview]
date: 2011-05-28T10:08:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

simple partial status epilepticus
type: Class
subclass of: status epilepticus
definition: "Simple partial SE consists of seizures that are localized to a discrete area of cerebral cortex and produce no alteration in consciousness." [web:http\://emedicine.medscape.com/article/1164462-overview]
date: 2011-05-28T10:10:13Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

frontal lobe epilepsy
type: Class
subclass of: epilepsy
definition: "A type of epilepsy characterized by brief, recurring seizures that arise in the frontal lobes of the brain, often while the patient is sleeping." [wikipedia:http\://en.wikipedia.org/wiki/Frontal_lobe_epilepsy]
date: 2011-05-28T10:14:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

nocturnal epilepsy
type: Class
subclass of: epilepsy
definition: A type of epilepsy characterised by seizure, usually tonic clonic, that occur only during sleep.
date: 2011-05-28T10:17:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: nocturnal epilepsy
annotated property: definition
annotated target: A type of epilepsy characterised by seizure, usually tonic clonic, that occur only during sleep.
source: NBO:GVG

photosensitive seizure
type: Class
subclass of: reflex seizure
definition: "A type of reflex seizure caused by visual stimuli that form patterns in time or space, such as flashing lights, bold, regular patterns, or regular moving patterns." [wikipedia:http\://en.wikipedia.org/wiki/Photosensitive_epilepsy]
date: 2011-05-28T11:11:25Z
created by: George Gkoutos
has exact synonym: photosensitive epilepsy
has OBO namespace: behavior_ontology

audiogenic seizure
type: Class
subclass of: reflex seizure
definition: A type of seizure induced by exposure to an auditory stimulus.
date: 2011-05-28T11:12:23Z
created by: George Gkoutos
has alternative id: NBO:0000725
has exact synonym: auditory stimulation induced seizure
has OBO namespace: behavior_ontology
xref: MP:0001496

Axiom
annotated source: audiogenic seizure
annotated property: definition
annotated target: A type of seizure induced by exposure to an auditory stimulus.
source: NBO:GVG

typical absence seizure
type: Class
subclass of: absence seizures
definition: An absence seizure induced by hyperventilation.
date: 2011-05-28T11:59:14Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: typical absence seizure
annotated property: definition
annotated target: An absence seizure induced by hyperventilation.
source: NBO:GVG

atypical absence seizure
type: Class
subclass of: absence seizures
definition: An absence seizure not induced by hyperventilation.
date: 2011-05-28T11:59:31Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0007270

Axiom
annotated source: atypical absence seizure
annotated property: definition
annotated target: An absence seizure not induced by hyperventilation.
source: NBO:GVG

secondary generalized seizure
type: Class
subclass of: generalized seizure
definition: A generalized seizure that was initiated as a partial seizure.
date: 2011-05-28T12:08:24Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002434

Axiom
annotated source: secondary generalized seizure
annotated property: definition
annotated target: A generalized seizure that was initiated as a partial seizure.
source: NBO:GVG

rapid secondary generalization
type: Class
subclass of: secondary generalized seizure
definition: A generalized seizure that was initiated as a partial seizure but very rapidly spread to both hemispheres.
date: 2011-05-28T12:11:05Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: rapid secondary generalization
annotated property: definition
annotated target: A generalized seizure that was initiated as a partial seizure but very rapidly spread to both hemispheres.
source: NBO:GVG

automatism
type: Class
subclass of: involuntary movement behavior phenotype
definition: Purposeless repetitive motor activities that often occur during a seizure.
date: 2011-05-28T12:14:35Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
comment: Automatisms may occur during complex partial or absence seizures.

Axiom
annotated source: automatism
annotated property: definition
annotated target: Purposeless repetitive motor activities that often occur during a seizure.
source: NBO:GVG

oral automatism
type: Class
subclass of: automatism
definition: An automatism characterised by involuntary oral activity such as lip smacking and swallowing.
date: 2011-05-28T12:15:48Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: oral automatism
annotated property: definition
annotated target: An automatism characterised by involuntary oral activity such as lip smacking and swallowing.
source: NBO:GVG

gestural automatism
type: Class
subclass of: automatism
definition: An automatism characterised by involuntary movement of the limbs or body such as fumbling, picking and rubbing.
date: 2011-05-28T12:17:42Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: gestural automatism
annotated property: definition
annotated target: An automatism characterised by involuntary movement of the limbs or body such as fumbling, picking and rubbing.
source: NBO:GVG

complex motor automatism
type: Class
subclass of: automatism
definition: An automatism characterised by stereotyped series of motor actions usually involving the limbs bilaterally such as swimming \nmovements, kicking movements and bicycling movements.
date: 2011-05-28T12:20:03Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: complex motor automatism
annotated property: definition
annotated target: An automatism characterised by stereotyped series of motor actions usually involving the limbs bilaterally such as swimming \nmovements, kicking movements and bicycling movements.
source: NBO:GVG

drug induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by the administration of a drug.
date: 2011-05-28T12:32:11Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: drug induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of a drug.
source: NBO:GVG

drug overdose induced seizure
type: Class
subclass of: drug induced seizure
definition: A type of seizure induced by accidental or intentional ingestion or application of a drug in quantities greater than recommended.
date: 2011-05-28T12:34:37Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: drug overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by accidental or intentional ingestion or application of a drug in quantities greater than recommended.
source: NBO:GVG

drug withdrawal induced seizure
type: Class
subclass of: drug induced seizure
definition: A type of seizure induced by termination of drug administration.
date: 2011-05-28T12:35:22Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: drug withdrawal induced seizure
annotated property: definition
annotated target: A type of seizure induced by termination of drug administration.
source: NBO:GVG

hypoglycemia induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by lower than normal level of blood glucose levels.
date: 2011-05-28T12:35:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002173

Axiom
annotated source: hypoglycemia induced seizure
annotated property: definition
annotated target: A type of seizure induced by lower than normal level of blood glucose levels.
source: GVG:NBO

cocaine overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of cocaine.
date: 2011-05-28T12:36:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: cocaine overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of cocaine.
source: NBO:GVG

isoniazide overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of isoniazide.
date: 2011-05-28T12:36:46Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: isoniazide overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of isoniazide.
source: NBO:GVG

amphetamine overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of amphetamine.
date: 2011-05-28T12:37:01Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: amphetamine overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of amphetamine.
source: NBO:GVG

antidepressant overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of antidepressant.
date: 2011-05-28T01:14:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: antidepressant overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of antidepressant.
source: NBO:GVG

theophylline overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of theophylline.
date: 2011-05-28T01:15:33Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: theophylline overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of theophylline.
source: NBO:GVG

penicillin overdose induced seizure
type: Class
subclass of: drug overdose induced seizure
definition: A type of seizure induced by the administration of penicillin.
date: 2011-05-28T01:16:56Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: penicillin overdose induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of penicillin.
source: NBO:GVG

alcohol withdrawal induced seizure
type: Class
subclass of: drug withdrawal induced seizure
definition: A type of seizure induced by termination of alcohol administration.
date: 2011-05-28T01:19:06Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: alcohol withdrawal induced seizure
annotated property: definition
annotated target: A type of seizure induced by termination of alcohol administration.
source: NBO:GVG

benzodiazepine withdrawal induced seizure
type: Class
subclass of: drug withdrawal induced seizure
definition: A type of seizure induced by termination of benzodiazepine administration.
date: 2011-05-28T01:22:57Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: benzodiazepine withdrawal induced seizure
annotated property: definition
annotated target: A type of seizure induced by termination of benzodiazepine administration.
source: NBO:GVG

barbiturates withdrawal induced seizure
type: Class
subclass of: drug withdrawal induced seizure
definition: A type of seizure induced by termination of barbiturates administration.
date: 2011-05-28T01:24:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: barbiturates withdrawal induced seizure
annotated property: definition
annotated target: A type of seizure induced by termination of barbiturates administration.
source: NBO:GVG

heroin withdrawal induced seizure
type: Class
subclass of: drug withdrawal induced seizure
definition: A type of seizure induced by termination of heroin administration.
date: 2011-05-28T01:26:05Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: heroin withdrawal induced seizure
annotated property: definition
annotated target: A type of seizure induced by termination of heroin administration.
source: NBO:GVG

hypomagnesemia induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by lower than normal level of blood magnesium levels.
date: 2011-05-28T01:34:40Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: hypomagnesemia induced seizure
annotated property: definition
annotated target: A type of seizure induced by lower than normal level of blood magnesium levels.
source: NBO:GVG

electrical stimulation induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by exposure to an electrical stimulus.
date: 2011-05-28T01:42:36Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: electrical stimulation induced seizure
annotated property: definition
annotated target: A type of seizure induced by exposure to an electrical stimulus.
source: NBO:GVG

trauma induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by the administration of a brain trauma.
date: 2011-05-28T03:39:02Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: trauma induced seizure
annotated property: definition
annotated target: A type of seizure induced by the administration of a brain trauma.
source: NBO:GVG

kindling induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by kindling, a repeated administration of seizure invoking stimulus which eventually results changes in the brain.
date: 2011-05-28T03:46:52Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: kindling induced seizure
annotated property: definition
annotated target: A type of seizure induced by kindling, a repeated administration of seizure invoking stimulus which eventually results changes in the brain.
source: NBO:GVG

electrical kindling induced seizure
type: Class
subclass of: kindling induced seizure
definition: A type of seizure induced by kindling, a repeated administration of electrical stimulus which eventually results changes in the brain.
date: 2011-05-28T03:50:30Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: electrical kindling induced seizure
annotated property: definition
annotated target: A type of seizure induced by kindling, a repeated administration of electrical stimulus which eventually results changes in the brain.
source: NBO:GVG

chemical kindling induced seizure
type: Class
subclass of: kindling induced seizure
definition: A type of seizure induced by kindling, a repeated administration of chemical stimulus which eventually results changes in the brain.
date: 2011-05-28T03:51:25Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: chemical kindling induced seizure
annotated property: definition
annotated target: A type of seizure induced by kindling, a repeated administration of chemical stimulus which eventually results changes in the brain.
source: NBO:GVG

auditory kindling induced seizure
type: Class
subclass of: kindling induced seizure
definition: A type of seizure induced by kindling, a repeated administration of auditory stimulus which eventually results changes in the brain.
date: 2011-05-28T03:52:15Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: auditory kindling induced seizure
annotated property: definition
annotated target: A type of seizure induced by kindling, a repeated administration of auditory stimulus which eventually results changes in the brain.
source: NBO:GVG

hemiclonic seizure
type: Class
subclass of: simple partial seizure with motor signs
definition: A simple partial seizure affecting the kinesthetic behavior of one side of the body.
date: 2011-05-28T05:51:10Z
created by: George Gkoutos
has exact synonym: unilateral clonic seizure
has OBO namespace: behavior_ontology
xref: HP:0006813

Axiom
annotated source: hemiclonic seizure
annotated property: definition
annotated target: A simple partial seizure affecting the kinesthetic behavior of one side of the body.
source: NBO:GVG

left side clonic seizure
type: Class
subclass of: hemiclonic seizure
definition: A simple partial seizure affecting the kinesthetic behavior of left side of the body.
date: 2011-05-28T06:01:58Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: left side clonic seizure
annotated property: definition
annotated target: A simple partial seizure affecting the kinesthetic behavior of left side of the body.
source: NBO:GVG

right side clonic seizure
type: Class
subclass of: hemiclonic seizure
definition: A simple partial seizure affecting the kinesthetic behavior of right side of the body.
date: 2011-05-28T06:03:17Z
created by: George Gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: right side clonic seizure
annotated property: definition
annotated target: A simple partial seizure affecting the kinesthetic behavior of right side of the body.
source: NBO:GVG

infantile spasm
type: Class
subclass of: spasm
subclass of: epilepsy
definition: A type of epileptic seizures occurring in infants and characterised by clusters of myoclonic spasms.
date: 2011-05-28T06:47:31Z
created by: George Gkoutos
has exact synonym: Generalized Flexion Epilepsy
has exact synonym: Infantile Epileptic Encephalopathy
has exact synonym: Infantile Myoclonic Encephalopathy
has exact synonym: Massive Myoclonia
has exact synonym: Salaam spasms
has exact synonym: West syndrome
has exact synonym: jackknife convulsions
has OBO namespace: behavior_ontology
xref: HP:0002391
xref: HP:0011097

Axiom
annotated source: infantile spasm
annotated property: definition
annotated target: A type of epileptic seizures occurring in infants and characterised by clusters of myoclonic spasms.
source: NBO:GVG

hypocalcemia induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by lower than normal level of blood calcium levels.
date: 2011-05-28T08:04:53Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002199

Axiom
annotated source: hypocalcemia induced seizure
annotated property: definition
annotated target: A type of seizure induced by lower than normal level of blood calcium levels.
source: NBO:GVG

secondary generalized tonic clonic seizure
type: Class
subclass of: secondary generalized seizure
definition: A generalized tonic clonic seizure that was initiated as a partial seizure.
date: 2011-05-28T08:28:12Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0002602

Axiom
annotated source: secondary generalized tonic clonic seizure
annotated property: definition
annotated target: A generalized tonic clonic seizure that was initiated as a partial seizure.
source: NBO:GVG

photostimulation induced seizure
type: Class
subclass of: provoked seizure
definition: A type of seizure induced by exposure to a light stimulus.
date: 2011-05-28T08:34:10Z
created by: George Gkoutos
has OBO namespace: behavior_ontology
xref: HP:0001327

Axiom
annotated source: photostimulation induced seizure
annotated property: definition
annotated target: A type of seizure induced by exposure to a light stimulus.
source: NBO:GVG

gelastic epilepsy
type: Class
subclass of: epilepsy
definition: A type of epilepsy that is characterised a sudden burst of energy, usually in the form of laughing.
date: 2011-05-28T11:12:42Z
created by: George Gkoutos
has exact synonym: gelastic seizure
has OBO namespace: behavior_ontology
xref: HP:0010821

Axiom
annotated source: gelastic epilepsy
annotated property: definition
annotated target: A type of epilepsy that is characterised a sudden burst of energy, usually in the form of laughing.
source: NBO:GVG

dacrystic epilepsy
type: Class
subclass of: epilepsy
definition: "A type of epilepsy that is characterised a sudden paroxysmal crying." [NBO:<new dbxref>, NBO:GVG]
date: 2011-05-28T11:18:45Z
created by: George Gkoutos
has exact synonym: dacrystic seizure
has OBO namespace: behavior_ontology
xref: HP:0010820

aggressive behavior by intent
type: Class
subclass of: aggressive behavior
date: 2012-02-16T01:16:13Z
created by: gkoutos
has OBO namespace: behavior_ontology

aggressive behavior by means
type: Class
subclass of: aggressive behavior
date: 2012-02-16T01:16:31Z
created by: gkoutos
has OBO namespace: behavior_ontology

autoaggressive behavior
type: Class
subclass of: aggressive behavior towards animals
definition: Agressive behavior towards oneself.
date: 2012-02-16T01:16:55Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: autoaggressive behavior
annotated property: definition
annotated target: Agressive behavior towards oneself.
source: NBO:GVG

social aggression behavior
type: Class
subclass of: aggressive behavior towards animals
subclass of: agonistic behavior
definition: An aggressive behavior towards other members of the society.
date: 2012-02-16T02:27:08Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: social aggression behavior
annotated property: definition
annotated target: An aggressive behavior towards other members of the society.
source: NBO:RH

perception behavior phenotype
type: Class
subclass of: cognitive behavior phenotype
date: 2012-03-16T04:51:23Z
created by: gkoutos
has OBO namespace: behavior_ontology

language communication behavior
type: Class
subclass of: communication behavior
definition: A social behavior related to the activity of conveying information by means of a system of arbitrary signals, such as voice sounds, gestures, or written symbols.
date: 2012-03-16T05:13:17Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: language communication behavior
annotated property: definition
annotated target: A social behavior related to the activity of conveying information by means of a system of arbitrary signals, such as voice sounds, gestures, or written symbols.
source: NBO:GVG

spatial perception
type: Class
equivalent class: Class
  intersection of: sensation behavior
  intersection of: Restriction
    on property: is_about
    some values from: PATO_0000117
subclass of: sensation behavior
subclass of: Restriction
  on property: is_about
  some values from: PATO_0000117
date: 2012-03-16T05:57:42Z
created by: gkoutos
has OBO namespace: behavior_ontology

jaw movement
type: Class
subclass of: mouth movement
date: 2012-03-17T09:51:17Z
created by: gkoutos
has OBO namespace: behavior_ontology

tongue movement
type: Class
subclass of: mouth movement
definition: The act of displacing part or all of the tongue from its current position [NBO:SMAC]
date: 2012-03-17T09:52:25Z
created by: gkoutos
has OBO namespace: behavior_ontology

blinking
type: Class
subclass of: eyelid movement
date: 2012-03-17T09:53:29Z
created by: gkoutos
has OBO namespace: behavior_ontology

eyelid movement
type: Class
subclass of: body part movement
date: 2012-03-17T09:54:30Z
created by: gkoutos
has OBO namespace: behavior_ontology

perception behavior by means
type: Class
subclass of: sensation behavior
date: 2012-03-16T05:23:06Z
created by: gkoutos
has OBO namespace: behavior_ontology

electrical nociceptive behavior
type: Class
equivalent class: Class
  intersection of: nociceptive behavior
  intersection of: Restriction
    on property: in_response_to
    some values from: detection of electrical stimulus involved in sensory perception of pain
subclass of: nociceptive behavior
subclass of: Restriction
  on property: in_response_to
  some values from: detection of electrical stimulus involved in sensory perception of pain
date: 2012-03-17T03:59:12Z
created by: gkoutos
has OBO namespace: behavior_ontology

non-rapid eye movement sleep behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sleeping behavior phenotype
subclass of: circadian behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: non-rapid eye movement sleep behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to all sleep stages in the circadian sleep/wake cycle other than REM sleep.
date: 2012-03-19T10:59:20Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: non-rapid eye movement sleep behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to all sleep stages in the circadian sleep/wake cycle other than REM sleep.
source: NBO:GVG

rapid eye movement sleep phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sleeping behavior phenotype
subclass of: circadian behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: circadian sleep/wake cycle, REM sleep
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
date: 2012-03-19T11:08:01Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: rapid eye movement sleep phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
source: NBO:GVG

reproductive behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: reproductive behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: reproductive behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the actions or interactions of an organism that are associated with reproduction.
date: 2012-03-19T02:08:56Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: reproductive behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the actions or interactions of an organism that are associated with reproduction.
source: NBO:GVG

mating behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: reproductive behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mating behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the interactions between organisms for the purpose of mating.
date: 2012-03-19T02:10:16Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: mating behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the interactions between organisms for the purpose of mating.
source: NBO:GVG

post-mating behavior phenotype
type: Class
subclass of: reproductive behavior phenotype
definition: Observable characteristic of behavior related to the specific actions or reactions of an organism following mating.
date: 2012-03-19T02:10:27Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: post-mating behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the specific actions or reactions of an organism following mating.
source: NBO:GVG

sexual activity phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: reproductive behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the activity which primary purpose is the sexual reproduction.
date: 2012-03-19T02:10:54Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: sexual activity phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the activity which primary purpose is the sexual reproduction.
source: NBO:GVG

courtship behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: mating behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic related to the behavioral interactions between organisms for the purpose of attracting sexual partners.
date: 2012-03-19T02:13:54Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: courtship behavior phenotype
annotated property: definition
annotated target: Observable characteristic related to the behavioral interactions between organisms for the purpose of attracting sexual partners.
source: NBO:GVG

female courtship behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: female courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: courtship behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: female courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the actions or reactions of a female, for the purpose of attracting a sexual partner.
date: 2012-03-19T02:16:31Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: female courtship behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the actions or reactions of a female, for the purpose of attracting a sexual partner.
source: NBO:GVG

male courtship behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: male courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: courtship behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: male courtship behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the actions or reactions of a male, for the purpose of attracting a sexual partner.
date: 2012-03-19T02:16:49Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: male courtship behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the actions or reactions of a male, for the purpose of attracting a sexual partner.
source: NBO:GVG

copulation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: copulation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: mating behavior phenotype
subclass of: sexual activity phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: copulation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the act of sexual union between male and female, involving the transfer of sperm.
date: 2012-03-19T02:22:41Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: copulation phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the act of sexual union between male and female, involving the transfer of sperm.
source: NBO:GVG

female sexual activity phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: female sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sexual activity phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: female sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the female activity which primary purpose is the sexual reproduction.
date: 2012-03-19T02:22:53Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: female sexual activity phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the female activity which primary purpose is the sexual reproduction.
source: NBO:GVG

male sexual activity phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: male sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: sexual activity phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: male sexual activity
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behavior related to the male activity which primary purpose is the sexual reproduction.
date: 2012-03-19T02:23:03Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: male sexual activity phenotype
annotated property: definition
annotated target: Observable characteristic of behavior related to the male activity which primary purpose is the sexual reproduction.
source: NBO:GVG

learning and/or memory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: learning and/or memory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: cognitive behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: learning and/or memory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the acquisition and processing of information and/or the storage and retrieval of this information over time.
date: 2012-03-19T02:33:56Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: learning and/or memory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the acquisition and processing of information and/or the storage and retrieval of this information over time.
source: NBO:GVG

learning behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: learning behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: learning and/or memory behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: learning behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour associated with any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
date: 2012-03-19T02:34:12Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: learning behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour associated with any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
source: NBO:GVG

memory behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: memory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: learning and/or memory behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: memory behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the ability of an organism's ability to store, retain, and recall information and experiences.
date: 2012-03-19T02:34:26Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: memory behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the ability of an organism's ability to store, retain, and recall information and experiences.
source: NBO:GVG

emission behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: emission behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: emission behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2012-03-19T03:46:31Z
created by: gkoutos
has OBO namespace: behavior_ontology

behavioral control of excretion phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of excretion
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: emission behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of excretion
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
date: 2012-03-19T03:46:55Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral control of excretion phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
source: NBO:GVG

behavioral control of defecation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of defecation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral control of excretion phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of defecation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the expulsion of feces from the rectum.
date: 2012-03-19T03:47:09Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral control of defecation phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the expulsion of feces from the rectum.
source: NBO:GVG

behavioral control of urination phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of urination
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral control of excretion phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of urination
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the regulation of body fluids process by which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
date: 2012-03-19T03:48:16Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral control of urination phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the regulation of body fluids process by which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
source: NBO:GVG

behavioral control of production of sound phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of production of sound
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: emission behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of production of sound
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2012-03-20T05:24:59Z
created by: gkoutos
has OBO namespace: behavior_ontology

behavioral control of external secretion phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of external secretion
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: emission behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of external secretion
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
date: 2012-03-20T05:25:03Z
created by: gkoutos
has OBO namespace: behavior_ontology

behavioral control of lacrimation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of lacrimation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral control of external secretion phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: behavioral control of lacrimation
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour related to the regulated release of the aqueous layer of the tear film from the lacrimal glands.
date: 2012-03-20T05:28:58Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: behavioral control of lacrimation phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour related to the regulated release of the aqueous layer of the tear film from the lacrimal glands.
source: NBO:GVG

crying behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: crying behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: emotional behavior phenotype
subclass of: behavioral control of production of sound phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: crying behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
date: 2012-03-20T05:30:38Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: crying behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
source: NBO:GVG

mobbing calling phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mobbing calling
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: emotional behavior phenotype
subclass of: behavioral control of production of sound phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: mobbing calling
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour associated with signals made by the mobbing species while harassing a predator.
date: 2012-03-20T05:32:31Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: mobbing calling phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour associated with signals made by the mobbing species while harassing a predator.
source: NBO:GVG

vocalization behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: vocalization behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
subclass of: behavioral control of production of sound phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: vocalization behavior
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0000001
definition: Observable characteristic of behaviour in which an organism produces sounds by a mechanism involving its respiratory system.
date: 2012-03-20T05:34:04Z
created by: gkoutos
has OBO namespace: behavior_ontology

Axiom
annotated source: vocalization behavior phenotype
annotated property: definition
annotated target: Observable characteristic of behaviour in which an organism produces sounds by a mechanism involving its respiratory system.
source: NBO:GVG

emotional conditioning
type: Class
equivalent class: Class
  intersection of: classical conditioning
  intersection of: Restriction
    on property: is_about
    some values from: emotional behavior
subclass of: classical conditioning
subclass of: Restriction
  on property: is_about
  some values from: emotional behavior
date: 2012-03-23T10:05:56Z
created by: gkoutos
has OBO namespace: behavior_ontology

increased amount of liquid in a single drinking act
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: drinking behavior
    intersection of: Restriction
      on property: has-input
      some values from: Class
        intersection of: PATO_0001548
        intersection of: Restriction
subclass of: drinking behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: drinking behavior
    intersection of: Restriction
      on property: has-input
      some values from: Class
        intersection of: PATO_0001548
        intersection of: Restriction

increased amount of liquid in drinking regulation
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: regulates
      some values from: Restriction
        on property: has-input
        some values from: Class
subclass of: drinking behavior phenotype
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: regulates
      some values from: Restriction
        on property: has-input
        some values from: Class

frequency of drinking
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000044
        intersection of: Restriction
subclass of: liquid preference/aversion
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000044
        intersection of: Restriction
note: 'participates in' some ('regulation of drinking behavior' and (has_quality some (frequency and (towards some 'liquid consumption'))))

increased frequency of drinking
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction
subclass of: frequency of drinking
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000380
        intersection of: Restriction

decreased frequency of drinking
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000381
        intersection of: Restriction
subclass of: frequency of drinking
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000381
        intersection of: Restriction

behavioral response to radiation
type: Class
subclass of: response to radiation
subclass of: sensation behavior
definition: Behavior as a result of an electromagnetic radiation stimulus.
created by: George Gkoutos

Axiom
annotated source: behavioral response to radiation
annotated property: definition
annotated target: Behavior as a result of an electromagnetic radiation stimulus.
source: NBO:GVG

behavioral response to light
type: Class
subclass of: response to light stimulus
subclass of: behavioral response to radiation
definition: Behavior as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
created by: George Gkoutos

Axiom
annotated source: behavioral response to light
annotated property: definition
annotated target: Behavior as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
source: NBO:GVG

behavioral response to chemical stimulus
type: Class
subclass of: sensation behavior
definition: Behavior as a result of a chemical stimulus.
created by: George Gkoutos

Axiom
annotated source: behavioral response to chemical stimulus
annotated property: definition
annotated target: Behavior as a result of a chemical stimulus.
source: NBO:GVG

behavioral response to xenobiotics
type: Class
equivalent class: Class
  intersection of: behavioral response to chemical stimulus
  intersection of: Restriction
    on property: in_response_to
    some values from: Restriction
      on property: has role
      some values from: xenobiotic
subclass of: behavioral response to chemical stimulus
subclass of: Restriction
  on property: in_response_to
  some values from: Restriction
    on property: has role
    some values from: xenobiotic
definition: Behavior as a result of a xenobiotic compound (compound foreign to living organisms) stimulus.
created by: George Gkoutos

Axiom
annotated source: behavioral response to xenobiotics
annotated property: definition
annotated target: Behavior as a result of a xenobiotic compound (compound foreign to living organisms) stimulus.
source: NBOC:GVG

behavioral response to addictive substance
type: Class
subclass of: behavioral response to xenobiotics
definition: Behavior as a result of sensitivity to an addictive substance intake.
created by: George Gkoutos

Axiom
annotated source: behavioral response to addictive substance
annotated property: definition
annotated target: Behavior as a result of sensitivity to an addictive substance intake.
source: NBOC:GVG

behavioral response to alcohol
type: Class
equivalent class: Class
  intersection of: behavioral response to addictive substance
  intersection of: Restriction
    on property: in_response_to
    some values from: alcohol consumption
subclass of: behavioral response to addictive substance
subclass of: Restriction
  on property: in_response_to
  some values from: alcohol consumption
definition: Behavior as a result of sensitivity to cocaine alcohol.

Axiom
annotated source: behavioral response to alcohol
annotated property: definition
annotated target: Behavior as a result of sensitivity to cocaine alcohol.
source: NBOC:GVG

regulation of behavior
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: behavior process
subclass of: behavior process
subclass of: Restriction
  on property: regulates
  some values from: behavior process
definition: "Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli." [GO:0050795]
created by: George Gkoutos
xref: GO:0050795

regulation of alcohol consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: alcohol consumption
subclass of: regulation of drinking behavior
subclass of: Restriction
  on property: regulates
  some values from: alcohol consumption
definition: Any process that modulates the frequency, rate or extent of alcohol consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of alcohol consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of alcohol consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

consumption behavior
type: Class
subclass of: behavior process
definition: Behavior related to the intake of substances.
created by: George Gkoutos
has broad synonym: ingest

Axiom
annotated source: consumption behavior
annotated property: definition
annotated target: Behavior related to the intake of substances.
source: NBOC:GVG

consumption of an addictive substance
type: Class
subclass of: consumption behavior
definition: Behavior related to the intake of addictive substances.
created by: George Gkoutos

Axiom
annotated source: consumption of an addictive substance
annotated property: definition
annotated target: Behavior related to the intake of addictive substances.
source: NBOC:GVG

cocaine consumption
type: Class
equivalent class: Class
  intersection of: consumption of an addictive substance
  intersection of: Restriction
    on property: has_participant
    some values from: cocaine
subclass of: consumption of an addictive substance
subclass of: Restriction
  on property: has_participant
  some values from: cocaine
definition: Behavior related to the intake of cocaine.
created by: George Gkoutos

Axiom
annotated source: cocaine consumption
annotated property: definition
annotated target: Behavior related to the intake of cocaine.
source: NBOC:GVG

morphine consumption
type: Class
equivalent class: Class
  intersection of: consumption of an addictive substance
  intersection of: Restriction
    on property: has_participant
    some values from: morphine
subclass of: consumption of an addictive substance
subclass of: Restriction
  on property: has_participant
  some values from: morphine
definition: Behavior related to the intake of morphine.
created by: George Gkoutos

Axiom
annotated source: morphine consumption
annotated property: definition
annotated target: Behavior related to the intake of morphine.
source: NBOC:GVG

behavioral response to cocaine
type: Class
equivalent class: Class
  intersection of: behavioral response to addictive substance
  intersection of: Restriction
    on property: in_response_to
    some values from: cocaine consumption
subclass of: behavioral response to addictive substance
subclass of: Restriction
  on property: in_response_to
  some values from: cocaine consumption
definition: Behavior as a result of sensitivity to cocaine intake.
xref: GO:0048148

Axiom
annotated source: behavioral response to cocaine
annotated property: definition
annotated target: Behavior as a result of sensitivity to cocaine intake.
source: NBOC:GVG

behavioral response to morphine
type: Class
equivalent class: Class
  intersection of: behavioral response to addictive substance
  intersection of: Restriction
    on property: in_response_to
    some values from: morphine consumption
subclass of: behavioral response to addictive substance
subclass of: Restriction
  on property: in_response_to
  some values from: morphine consumption
definition: Behavior as a result of sensitivity to morphine
created by: George Gkoutos

Axiom
annotated source: behavioral response to morphine
annotated property: definition
annotated target: Behavior as a result of sensitivity to morphine
source: NBOC:GVG

behavioral response to nicotine
type: Class
equivalent class: Class
  intersection of: behavioral response to addictive substance
  intersection of: Restriction
    on property: in_response_to
    some values from: nicotine consumption
subclass of: behavioral response to addictive substance
subclass of: Restriction
  on property: in_response_to
  some values from: nicotine consumption
definition: Behavior as a result of sensitivity to nicotine intake.
created by: George Gkoutos
xref: GO:0035095

Axiom
annotated source: behavioral response to nicotine
annotated property: definition
annotated target: Behavior as a result of sensitivity to nicotine intake.
source: NBOC:GVG

nicotine consumption
type: Class
equivalent class: Class
  intersection of: consumption of an addictive substance
  intersection of: Restriction
    on property: has_participant
    some values from: nicotine
subclass of: consumption of an addictive substance
subclass of: Restriction
  on property: has_participant
  some values from: nicotine
definition: Behavior related to the intake of nicotine.
created by: George Gkoutos

Axiom
annotated source: nicotine consumption
annotated property: definition
annotated target: Behavior related to the intake of nicotine.
source: NBOC:GVG

regulation of cocaine consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: cocaine consumption
subclass of: regulation of consumption of an addictive substance
subclass of: Restriction
  on property: regulates
  some values from: cocaine consumption
definition: Any process that modulates the frequency, rate or extent of cocaine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of cocaine consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of cocaine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of consumption behavior
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: consumption behavior
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: consumption behavior
definition: Any process that modulates the frequency, rate or extent of consumption behavior, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of consumption behavior
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of consumption behavior, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of consumption of an addictive substance
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: consumption of an addictive substance
subclass of: regulation of consumption behavior
subclass of: Restriction
  on property: regulates
  some values from: consumption of an addictive substance
definition: Any process that modulates the frequency, rate or extent of consumption of an addictive substance, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of consumption of an addictive substance
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of consumption of an addictive substance, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of nicotine consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: nicotine consumption
subclass of: regulation of consumption of an addictive substance
subclass of: Restriction
  on property: regulates
  some values from: nicotine consumption
definition: Any process that modulates the frequency, rate or extent of nicotine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of nicotine consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of nicotine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of morphine consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: morphine consumption
subclass of: regulation of consumption of an addictive substance
subclass of: Restriction
  on property: regulates
  some values from: morphine consumption
definition: Any process that modulates the frequency, rate or extent of morphine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of morphine consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of morphine consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

behavioral response to anesthetic
type: Class
subclass of: behavioral response to xenobiotics
definition: Behavior as a result of sensitivity to an anasthetic intake.
created by: George Gkoutos

Axiom
annotated source: behavioral response to anesthetic
annotated property: definition
annotated target: Behavior as a result of sensitivity to an anasthetic intake.
source: NBOC:GVG

nursing behavior
type: Class
subclass of: maternal nurturing behavior
definition: Maternal behavior related to the nursing offspring.

Axiom
annotated source: nursing behavior
annotated property: definition
annotated target: Maternal behavior related to the nursing offspring.
source: NBOC:GVG

regulation of feeding behavior
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: Class
    union of: liquid consumption
    union of: food consumption
subclass of: regulation of consumption behavior
subclass of: Restriction
  on property: regulates
  some values from: Class
    union of: liquid consumption
    union of: food consumption
definition: Any process that modulates the frequency, rate or extent of consumption of food or liquid
created by: George Gkoutos

Axiom
annotated source: regulation of feeding behavior
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of consumption of food or liquid
source: NBOC:GVG

regulation of water consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: water consumption
subclass of: regulation of drinking behavior
subclass of: Restriction
  on property: regulates
  some values from: water consumption
definition: Any process that modulates the frequency, rate or extent of water consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of water consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of water consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of saccharin consumption
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: saccharin consumption
subclass of: regulation of eating behavior
subclass of: Restriction
  on property: regulates
  some values from: saccharin consumption
definition: Any process that modulates the frequency, rate or extent of saccharin consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of saccharin consumption
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of saccharin consumption, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

adipsia
type: Class
equivalent class: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000381
        intersection of: Restriction
subclass of: decreased frequency of drinking
subclass of: Restriction
  on property: BFO_0000056
  some values from: Class
    intersection of: regulation of drinking behavior
    intersection of: Restriction
      on property: has quality
      some values from: Class
        intersection of: PATO_0000381
        intersection of: Restriction
definition: A pathological drinking behavior characterised by a lack of desire to drink.
created by: George Gkoutos
xref: MP:0001428

Axiom
annotated source: adipsia
annotated property: definition
annotated target: A pathological drinking behavior characterised by a lack of desire to drink.
source: NBO:GVG

stress-induced hypothermia
type: Class
subclass of: stress related behavior
subclass of: Restriction
  on property: in_response_to
  some values from: PATO_0001305
definition: Increase in core body termperature in response to stress or anticipatory anxiety.
created by: George Gkoutos

Axiom
annotated source: stress-induced hypothermia
annotated property: definition
annotated target: Increase in core body termperature in response to stress or anticipatory anxiety.
source: NBOC:GVG

regulation of sexual activity
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: sexual activity
subclass of: regulation of behavior
subclass of: Restriction
  on property: regulates
  some values from: sexual activity
definition: Any process that modulates the frequency, rate or extent of sexual activity, the specific actions or reactions of an organism in response to external or internal stimuli.
created by: George Gkoutos

Axiom
annotated source: regulation of sexual activity
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of sexual activity, the specific actions or reactions of an organism in response to external or internal stimuli.
source: NBOC:GVG

regulation of drinking preference behavior
type: Class
subclass of: regulation of drinking behavior
definition: A regulation of drinking behavior process associated with the preference over the type of liquids that are consumed.
created by: George Gkoutos

Axiom
annotated source: regulation of drinking preference behavior
annotated property: definition
annotated target: A regulation of drinking behavior process associated with the preference over the type of liquids that are consumed.
source: NBO:GVG

regulation of alcohol preference behavior
type: Class
equivalent class: Class
  intersection of: regulation of drinking preference behavior
  intersection of: Restriction
    on property: has_participant
    some values from: ethanol
subclass of: regulation of drinking preference behavior
subclass of: Restriction
  on property: has_participant
  some values from: ethanol
definition: A regulation of drinking behavior process associated with the preference over alchohol consumption.
created by: George Gkoutos

Axiom
annotated source: regulation of alcohol preference behavior
annotated property: definition
annotated target: A regulation of drinking behavior process associated with the preference over alchohol consumption.
source: NBO:GVG

regulation of eating preference behavior
type: Class
subclass of: regulation of eating behavior
definition: A regulation of drinking behavior process associated with the preference over the type of food that is consumed.
created by: George Gkoutos

Axiom
annotated source: regulation of eating preference behavior
annotated property: definition
annotated target: A regulation of drinking behavior process associated with the preference over the type of food that is consumed.
source: NBO:GVG

regulation of saccharin preference behavior
type: Class
equivalent class: Class
  intersection of: regulation of eating preference behavior
  intersection of: Restriction
    on property: has_participant
    some values from: saccharin
subclass of: regulation of eating preference behavior
subclass of: Restriction
  on property: has_participant
  some values from: saccharin
definition: A regulation of drinking behavior process associated with the preference over saccharing consumption.
created by: George Gkoutos

Axiom
annotated source: regulation of saccharin preference behavior
annotated property: definition
annotated target: A regulation of drinking behavior process associated with the preference over saccharing consumption.
source: NBO:GVG

regulation of addictive substance consumption preference
type: Class
subclass of: regulation of consumption of an addictive substance
definition: A regulation of consumption of an addictive sustance behavior process associated with the preference over the type of addictive sustance that is consumed.
created by: George Gkoutos

Axiom
annotated source: regulation of addictive substance consumption preference
annotated property: definition
annotated target: A regulation of consumption of an addictive sustance behavior process associated with the preference over the type of addictive sustance that is consumed.
source: NBO:GVG