C elegans Phenotype Ontology
type: Ontology
version IRI: wbphenotype-base.owl
IAO_0000700: WBPhenotype_0000886
description: Ontology about C. elegans and other nematode phenotypes
type: IAO_8000001
license: http://creativecommons.org/licenses/by/4.0/
default-namespace: C_elegans_phenotype_ontology
saved-by: chris-grove
version info: 2025-08-12

chromosome instability
type: Class
subclass of: cell homeostasis metabolism variant
IAO_0000115: Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000000

Axiom
annotated source: chromosome instability
annotated property: IAO_0000115
annotated target: Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control.
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

body posture variant
type: Class
subclass of: organism behavior variant
IAO_0000115: Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered.
has narrow synonym: body posture abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000001
in subset: phenotype slim wb

Axiom
annotated source: body posture variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered.
has db xref: WB:WBPerson557
has db xref: WB:cab

kinker
type: Class
subclass of: WBPhenotype_0004017
IAO_0000115: The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000002

Axiom
annotated source: kinker
annotated property: IAO_0000115
annotated target: The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

obsolete flattened locomotion path
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: WBPhenotype_0001309
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000003
deprecated: true

constitutive egg laying
type: Class
subclass of: hyperactive egg laying
IAO_0000115: Eggs are laid under conditions where egg laying is normally inhibited.
has broad synonym: Egl c
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000004
comment: Liquid M9.

Axiom
annotated source: constitutive egg laying
annotated property: IAO_0000115
annotated target: Eggs are laid under conditions where egg laying is normally inhibited.
has db xref: WB:cab

hyperactive egg laying
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: egg laying variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000005

Axiom
annotated source: hyperactive egg laying
annotated property: IAO_0000115
annotated target: Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control.
has db xref: WB:cab

egg laying defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: BFO_0000070
      some values from: GO_0018991
subclass of: egg laying variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: BFO_0000070
      some values from: GO_0018991
IAO_0000115: Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control.
has broad synonym: Egl d
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000006

Axiom
annotated source: egg laying defective
annotated property: IAO_0000115
annotated target: Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00004651
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:WBPaper00024497
has db xref: WB:WBPaper00025054
has db xref: WB:cab

bag of worms
type: Class
subclass of: WBPhenotype_0000862
IAO_0000115: A worm carcass is formed with retained eggs that hatch inside.
has broad synonym: Bag
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000007

Axiom
annotated source: bag of worms
annotated property: IAO_0000115
annotated target: A worm carcass is formed with retained eggs that hatch inside.
has db xref: WB:cab

anesthetic hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38867
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: anesthetic response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38867
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals.
has exact synonym: anaesthetic hypersensitive
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000008

Axiom
annotated source: anesthetic hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

anesthetic resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38867
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: anesthetic response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38867
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has exact synonym: anaesthetic resistant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000009

Axiom
annotated source: anesthetic resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

drug hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23888
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23888
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000010

Axiom
annotated source: drug hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

drug resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23888
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23888
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000011

Axiom
annotated source: drug resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.
has db xref: WB:WBPerson557

dauer constitutive
type: Class
subclass of: dauer formation variant
IAO_0000115: Formation of dauer larvae under conditions that do not favor dauer formation.
has broad synonym: Daf c
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000012

Axiom
annotated source: dauer constitutive
annotated property: IAO_0000115
annotated target: Formation of dauer larvae under conditions that do not favor dauer formation.
has db xref: WB:kmva

dauer defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043053
subclass of: dauer formation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043053
IAO_0000115: Failure to form dauer larvae under dauer-inducing conditions.
has broad synonym: Daf d
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000013

Axiom
annotated source: dauer defective
annotated property: IAO_0000115
annotated target: Failure to form dauer larvae under dauer-inducing conditions.
has db xref: WB:kmva

cord commissures variant
type: Class
subclass of: WBPhenotype_0001226
IAO_0000115: Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals.
has narrow synonym: cord commissures abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000014

Axiom
annotated source: cord commissures variant
annotated property: IAO_0000115
annotated target: Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPaper00029065
has db xref: WB:WBPerson712

positive chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
subclass of: positive chemotaxis variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001558
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
IAO_0000115: Variations in the movement towards typically attractive chemicals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000015

Axiom
annotated source: positive chemotaxis defective
annotated property: IAO_0000115
annotated target: Variations in the movement towards typically attractive chemicals.
has db xref: WB:cab

aldicarb hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: acetylcholinesterase inhibitor hypersensitive
subclass of: aldicarb response variant
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals.
has broad synonym: Hic
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000016

Axiom
annotated source: aldicarb hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

aldicarb resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: aldicarb response variant
subclass of: WBPhenotype_0001289
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has broad synonym: Ald R
has broad synonym: Ric
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000017

Axiom
annotated source: aldicarb resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

pharyngeal pumping increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001006
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000018

Axiom
annotated source: pharyngeal pumping increased
annotated property: IAO_0000115
annotated target: The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals.
has db xref: WB:WBPerson712

pharyngeal pumping reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001006
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Pharyngeal pumping motion occurs at a slower rate than control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000019

Axiom
annotated source: pharyngeal pumping reduced
annotated property: IAO_0000115
annotated target: Pharyngeal pumping motion occurs at a slower rate than control animals.
has db xref: WB:WBPaper00001709

pharyngeal pumping irregular
type: Class
subclass of: WBPhenotype_0001006
IAO_0000115: Pharyngeal pumping motion occurs at intervals that vary from control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000020

Axiom
annotated source: pharyngeal pumping irregular
annotated property: IAO_0000115
annotated target: Pharyngeal pumping motion occurs at intervals that vary from control animals.
has db xref: WB:WBPaper00001709

squat
type: Class
subclass of: body size variant
IAO_0000115: Squat animals are dumpy as homozygotes, but roll as heterozygotes.
has broad synonym: Sqt
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000021

Axiom
annotated source: squat
annotated property: IAO_0000115
annotated target: Squat animals are dumpy as homozygotes, but roll as heterozygotes.
has db xref: WB:WBPaper00000906

long
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000573
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: large
subclass of: WBPhenotype_0001726
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000573
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals are longer than control animals at the same developmental stage.
has broad synonym: Lon
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000022

Axiom
annotated source: long
annotated property: IAO_0000115
annotated target: Animals are longer than control animals at the same developmental stage.
has db xref: WB:cab
has db xref: WB:cgc31

serotonin hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000023

Axiom
annotated source: serotonin hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

serotonin resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000024

Axiom
annotated source: serotonin resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

blistered
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001928
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000948
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001928
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Fluid-filled blisters appear on the cuticle.
has broad synonym: Bli
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000025

Axiom
annotated source: blistered
annotated property: IAO_0000115
annotated target: Fluid-filled blisters appear on the cuticle.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:WBPaper00024497
has db xref: WB:cab
has db xref: WB:cgc31

lipid depleted
type: Class
subclass of: WBPhenotype_0001183
IAO_0000115: Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva.
has broad synonym: Lpd
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: fat depleted
id: WBPhenotype:0000026

Axiom
annotated source: lipid depleted
annotated property: IAO_0000115
annotated target: Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva.
has db xref: GO:0006629
has db xref: WB:WBPaper00005707
has db xref: WB:WBPerson712

organism metabolism processing variant
type: Class
subclass of: organism homeostasis metabolism variant
IAO_0000115: Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control.
has narrow synonym: organism metabolism processing abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000027

Axiom
annotated source: organism metabolism processing variant
annotated property: IAO_0000115
annotated target: Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control.
has db xref: GO:0008152
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

RNA processing variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006396
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: RNA expression variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006396
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control.
has narrow synonym: RNA processing abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000028

Axiom
annotated source: RNA processing variant
annotated property: IAO_0000115
annotated target: Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control.
has db xref: GO:0006396
has db xref: WB:WBPerson2021

systemic RNAi variant
type: Class
subclass of: WBPhenotype_0000743
IAO_0000115: Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
has narrow synonym: systemic RNAi abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Environmental RNAi defective
id: WBPhenotype:0000029

Axiom
annotated source: systemic RNAi variant
annotated property: IAO_0000115
annotated target: Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
has db xref: WB:WBPaper00029209
has db xref: WB:WBPaper00030758
has db xref: WB:WBPerson712

growth variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040007
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism homeostasis metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040007
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals.
has narrow synonym: growth abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000030

Axiom
annotated source: growth variant
annotated property: IAO_0000115
annotated target: Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals.
has db xref: GO:0040007
has db xref: WB:WBPerson2021

slow growth
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040007
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: general pace of development variant
subclass of: retarded heterochronic variations
subclass of: growth rate variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040007
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that causes a reduction in growth rate compared to control.
has broad synonym: Gro
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000031

Axiom
annotated source: slow growth
annotated property: IAO_0000115
annotated target: Any variation that causes a reduction in growth rate compared to control.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00004403
has db xref: WB:WBPaper00004651
has db xref: WB:WBPaper00004769
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:WBPaper00024497
has db xref: WB:WBPerson557
has db xref: WB:cab

sick
type: Class
subclass of: growth variant
IAO_0000115: Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
has broad synonym: Sck
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000032

Axiom
annotated source: sick
annotated property: IAO_0000115
annotated target: Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
has db xref: WB:WBPaper00000179
has db xref: WB:WBPaper00000565
has db xref: WB:WBPerson712

developmental timing variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040034
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040034
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues.
has alternative id: WBPhenotype:0000437
has exact synonym: heterochronic defect
has narrow synonym: developmental timing abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000033
in subset: phenotype slim wb
comment: Possible XP GO:0040034.

Axiom
annotated source: developmental timing variant
annotated property: IAO_0000115
annotated target: The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues.
has db xref: WB:cab
has db xref: pmid:6494891

embryonic polarity variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001769
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBls_0000003
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001769
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBls_0000003
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
has narrow synonym: embryonic polarity abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000034

Axiom
annotated source: embryonic polarity variant
annotated property: IAO_0000115
annotated target: Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
has db xref: WB:WBPaper00005079
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson712

larval body morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
subclass of: body morphology variant
subclass of: WBPhenotype_0000934
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
IAO_0000115: Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals.
has narrow synonym: larval body morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: larval morphology abnormal
id: WBPhenotype:0000035
in subset: phenotype slim wb

Axiom
annotated source: larval body morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

adult body morphology variant
type: Class
subclass of: body morphology variant
subclass of: WBPhenotype_0000934
IAO_0000115: Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals.
has narrow synonym: adult body morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000036
in subset: phenotype slim wb

Axiom
annotated source: adult body morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

egg morphology variant
type: Class
subclass of: WBPhenotype_0000934
IAO_0000115: Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals.
has narrow synonym: egg morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000037
in subset: phenotype slim wb

Axiom
annotated source: egg morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals.
has db xref: WB:WBPaper00001075
has db xref: WB:WBPerson2021

exploded through vulva
type: Class
subclass of: epithelial system development variant
IAO_0000115: The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
has broad synonym: Rup
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: burst vulva
has related synonym: gonad eversion
has related synonym: gonad exploded through vulva
has related synonym: rupture through vulva
id: WBPhenotype:0000038

Axiom
annotated source: exploded through vulva
annotated property: IAO_0000115
annotated target: The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
has db xref: WB:WBPaper00027633
has db xref: WB:WBPaper00031094
has db xref: WB:WBPerson712

life span phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000050
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism physiology phenotype
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000050
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Adult life span is either longer or shorter than typical of control animals.
has broad synonym: Age
has exact synonym: life span abnormal
has exact synonym: life span variant
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: longevity abnormal
id: WBPhenotype:0000039
in subset: phenotype slim wb

Axiom
annotated source: life span phenotype
annotated property: IAO_0000115
annotated target: Adult life span is either longer or shorter than typical of control animals.
has db xref: GO:0008340
has db xref: WB:WBPaper00005863
has db xref: WB:WBPaper00026717
has db xref: WB:WBPerson557
has db xref: WB:cab

one cell arrest early emb
type: Class
subclass of: WBPhenotype_0001100
IAO_0000115: Embryos fail to divide and arrest as one-cell embryos.
has broad synonym: Emb
has broad synonym: Ocs
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: catastrophic one cell arrest
id: WBPhenotype:0000040

Axiom
annotated source: one cell arrest early emb
annotated property: IAO_0000115
annotated target: Embryos fail to divide and arrest as one-cell embryos.
has db xref: WB:cab
has db xref: WB:cgc5599

Axiom
annotated source: one cell arrest early emb
annotated property: hasRelatedSynonym
annotated target: catastrophic one cell arrest
has db xref: WB:cgc5599

osmotic integrity variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030104
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism homeostasis metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030104
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control.
has narrow synonym: osmotic integrity abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: osmoregulation variant
id: WBPhenotype:0000041

Axiom
annotated source: osmotic integrity variant
annotated property: IAO_0000115
annotated target: Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control.
has db xref: GO:0030104
has db xref: WB:WBPerson2021

slow embryonic development
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: slow development
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009790
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The progression through stages between fertilization to hatching are temporally retarded.
has broad synonym: Sle
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000042

Axiom
annotated source: slow embryonic development
annotated property: IAO_0000115
annotated target: The progression through stages between fertilization to hatching are temporally retarded.
has db xref: WB:WBPerson712

general pace of development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000161
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: developmental timing variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000161
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals.
has narrow synonym: general pace of development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000043
in subset: phenotype slim wb

Axiom
annotated source: general pace of development variant
annotated property: IAO_0000115
annotated target: Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

egg size defective early emb
type: Class
subclass of: WBPhenotype_0001100
subclass of: WBPhenotype_0002407
IAO_0000115: Egg is smaller or larger compared to eggs of control animals.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000044

Axiom
annotated source: egg size defective early emb
annotated property: IAO_0000115
annotated target: Egg is smaller or larger compared to eggs of control animals.
has db xref: WB:cab
has db xref: WB:cgc7141

developmental delay postembryonic
type: Class
subclass of: postembryonic development variant
subclass of: WBPhenotype_0000848
IAO_0000115: The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000045

Axiom
annotated source: developmental delay postembryonic
annotated property: IAO_0000115
annotated target: The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control.
has db xref: WB:WBPaper00025054
has db xref: WB:cab

pace of P lineage defective early emb
type: Class
subclass of: WBPhenotype_0000746
subclass of: WBPhenotype_0000824
IAO_0000115: More than five minutes between AB and P1 divisions.
has broad synonym: Emb
has narrow synonym: pace of P lineage abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000046

Axiom
annotated source: pace of P lineage defective early emb
annotated property: IAO_0000115
annotated target: More than five minutes between AB and P1 divisions.
has db xref: WB:cab
has db xref: WB:cgc7141

gastrulation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007369
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007369
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
has narrow synonym: gastrulation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000047

Axiom
annotated source: gastrulation variant
annotated property: IAO_0000115
annotated target: Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
has db xref: WB:WBPaper00027251
has db xref: WB:WBPerson2021

hatching variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the ability of an animal to emerge from the protective egg shell compared to control animals.
has narrow synonym: hatching abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000048

Axiom
annotated source: hatching variant
annotated property: IAO_0000115
annotated target: Variations in the ability of an animal to emerge from the protective egg shell compared to control animals.
has db xref: GO:0035188
has db xref: WB:WBPerson2021

postembryonic development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009791
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009791
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of an animal over time, from hatching to adulthood, compared to control.
has narrow synonym: postembryonic development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000049
in subset: phenotype slim wb

Axiom
annotated source: postembryonic development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of an animal over time, from hatching to adulthood, compared to control.
has db xref: WB:WBPerson2021

embryonic lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
subclass of: lethal
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
IAO_0000115: Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: egg lethal
has related synonym: embryonic death
has related synonym: inviable zygote
id: WBPhenotype:0000050
in subset: phenotype slim wb

Axiom
annotated source: embryonic lethal
annotated property: IAO_0000115
annotated target: Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
has db xref: WB:WBPaper00000179
has db xref: WB:WBPaper00004403
has db xref: WB:WBPaper00004540
has db xref: WB:WBPaper00004651
has db xref: WB:WBPaper00004769
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00024497
has db xref: WB:WBPaper00024925
has db xref: WB:WBPaper00025054
has db xref: WB:cab

embryonic terminal arrest variable emb
type: Class
subclass of: terminal arrest variable
subclass of: WBPhenotype_0000749
IAO_0000115: The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal.
has broad synonym: Emb
has broad synonym: Etv
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000051

Axiom
annotated source: embryonic terminal arrest variable emb
annotated property: IAO_0000115
annotated target: The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal.
has db xref: GO:0009790
has db xref: WB:WBPaper00004811
has db xref: WB:WBPaper00024944
has db xref: WB:WBPerson712

maternal effect lethal emb
type: Class
subclass of: embryonic lethal
IAO_0000115: Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
has broad synonym: Emb
has broad synonym: Mel
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000052

Axiom
annotated source: maternal effect lethal emb
annotated property: IAO_0000115
annotated target: Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
has db xref: WB:WBPaper00001109
has db xref: WB:WBPerson2021

paralyzed arrested elongation two fold
type: Class
subclass of: embryonic lethal
subclass of: two fold arrest
IAO_0000115: Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae.
has broad synonym: Pat
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: active elongation arrest
has related synonym: two fold arrest
id: WBPhenotype:0000053

Axiom
annotated source: paralyzed arrested elongation two fold
annotated property: IAO_0000115
annotated target: Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae.
has db xref: WB:cab
has db xref: WB:cgc1894

larval lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
subclass of: lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
IAO_0000115: The animal dies at any time between hatching and onset to adulthood.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: larval death
id: WBPhenotype:0000054
in subset: phenotype slim wb

Axiom
annotated source: larval lethal
annotated property: IAO_0000115
annotated target: The animal dies at any time between hatching and onset to adulthood.
has db xref: GO:0002119
has db xref: WB:WBPerson712

early larval arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: ends during or before
      some values from: WBls_0000027
    intersection of: Restriction
      on property: starts during or after
      some values from: WBls_0000024
subclass of: larval arrest
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: ends during or before
      some values from: WBls_0000027
    intersection of: Restriction
      on property: starts during or after
      some values from: WBls_0000024
IAO_0000115: Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000055

Axiom
annotated source: early larval arrest
annotated property: IAO_0000115
annotated target: Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development.
has db xref: WB:cab

late larval arrest
type: Class
subclass of: larval arrest
IAO_0000115: Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000056

Axiom
annotated source: late larval arrest
annotated property: IAO_0000115
annotated target: Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development.
has db xref: WB:cab

early larval lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: ends during or before
      some values from: WBls_0000027
    intersection of: Restriction
      on property: starts during or after
      some values from: WBls_0000024
subclass of: larval lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: ends during or before
      some values from: WBls_0000027
    intersection of: Restriction
      on property: starts during or after
      some values from: WBls_0000024
IAO_0000115: Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000057

Axiom
annotated source: early larval lethal
annotated property: IAO_0000115
annotated target: Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle.
has db xref: WB:WBPerson2021

late larval lethal
type: Class
subclass of: larval lethal
IAO_0000115: Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000058

Axiom
annotated source: late larval lethal
annotated property: IAO_0000115
annotated target: Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle.
has db xref: WB:WBPerson2021

larval arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
subclass of: WBPhenotype_0000750
subclass of: WBPhenotype_0001016
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
IAO_0000115: The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
has broad synonym: Lva
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000059

Axiom
annotated source: larval arrest
annotated property: IAO_0000115
annotated target: The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
has db xref: WB:WBPaper00002958
has db xref: WB:WBPerson2021

adult lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000041
subclass of: lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000041
IAO_0000115: Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
has broad synonym: Adl
has broad synonym: Let
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000060
in subset: phenotype slim wb

Axiom
annotated source: adult lethal
annotated property: IAO_0000115
annotated target: Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:cab

Axiom
annotated source: adult lethal
annotated property: hasBroadSynonym
annotated target: Adl
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00005654

extended life span
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001603
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
subclass of: life span phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001603
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
IAO_0000115: The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
has broad synonym: Age
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: life span increased
has related synonym: longevity increased
id: WBPhenotype:0000061

Axiom
annotated source: extended life span
annotated property: IAO_0000115
annotated target: The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
has db xref: GO:0008340
has db xref: WB:WBPerson712

lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
subclass of: organism development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
IAO_0000115: Animals die prematurely at any stage of the life cycle.
has broad synonym: Let
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000062
in subset: phenotype slim wb

Axiom
annotated source: lethal
annotated property: IAO_0000115
annotated target: Animals die prematurely at any stage of the life cycle.
has db xref: WB:WBPaper00001109
has db xref: WB:WBPerson2021

terminal arrest variable
type: Class
subclass of: lethal
IAO_0000115: Variations that cause developmental progression to cease at different stages of the lifecycle.
has broad synonym: Var
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000063

Axiom
annotated source: terminal arrest variable
annotated property: IAO_0000115
annotated target: Variations that cause developmental progression to cease at different stages of the lifecycle.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

sexually dimorphic lethality
type: Class
subclass of: lethal
IAO_0000115: Animals die prematurely at any stage of the life cycle in a sex dependent manner.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Let
id: WBPhenotype:0000064

Axiom
annotated source: sexually dimorphic lethality
annotated property: IAO_0000115
annotated target: Animals die prematurely at any stage of the life cycle in a sex dependent manner.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

X0 lethal
type: Class
subclass of: sexually dimorphic lethality
IAO_0000115: XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals.
has broad synonym: Let
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: male specific lethality
id: WBPhenotype:0000065
in subset: phenotype slim wb

Axiom
annotated source: X0 lethal
annotated property: IAO_0000115
annotated target: XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals.
has db xref: WB:WBPerson363
has db xref: WB:WBPerson712

XX lethal
type: Class
subclass of: sexually dimorphic lethality
IAO_0000115: XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: hermaphrodite specific lethality
id: WBPhenotype:0000066
in subset: phenotype slim wb

Axiom
annotated source: XX lethal
annotated property: IAO_0000115
annotated target: XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals.
has db xref: WB:WBPerson363
has db xref: WB:WBPerson712

organism stress response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006950
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006950
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in response to stress stimuli compared to control animals.
has narrow synonym: organism stress response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000067

Axiom
annotated source: organism stress response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in response to stress stimuli compared to control animals.
has db xref: GO:0006950
has db xref: WB:WBPerson712

cellular oxidative stress response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034599
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell stress response variant
subclass of: chemical response variant
subclass of: WBPhenotype_0001620
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034599
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control.
has narrow synonym: oxidative stress response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000068

Axiom
annotated source: cellular oxidative stress response variant
annotated property: IAO_0000115
annotated target: Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control.
has db xref: GO:0034599
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

progeny variant
type: Class
subclass of: organism development variant
IAO_0000115: Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control.
has narrow synonym: progeny abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000069
in subset: phenotype slim wb

Axiom
annotated source: progeny variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male tail morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0007850
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: tail morphology variant
subclass of: WBPhenotype_0001024
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0007850
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan.
has broad synonym: Mab
has narrow synonym: male tail morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000070

Axiom
annotated source: male tail morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan.
has db xref: WB:WBPaper00027278
has db xref: WB:WBPerson712

head morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body region morphology variant
subclass of: organism segment morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control.
has narrow synonym: head morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000071

Axiom
annotated source: head morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005740
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body region morphology variant
subclass of: organism segment morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005740
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals.
has narrow synonym: body morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000072
in subset: phenotype slim wb

Axiom
annotated source: body morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

tail morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body region morphology variant
subclass of: organism segment morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas).
has narrow synonym: tail morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000073

Axiom
annotated source: tail morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

genetic pathway variant
type: Class
subclass of: organism physiology phenotype
IAO_0000115: Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
has narrow synonym: genetic pathway abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000074
in subset: phenotype slim wb

Axiom
annotated source: genetic pathway variant
annotated property: IAO_0000115
annotated target: Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cuticle attachment variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040004
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cuticle development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040004
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas).
has narrow synonym: cuticle attachment abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000075

Axiom
annotated source: cuticle attachment variant
annotated property: IAO_0000115
annotated target: Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

epithelial attachment variant
type: Class
subclass of: epithelial system physiology variant
IAO_0000115: Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control.
has narrow synonym: epithelial attachment abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: hypodermal attachment abnormal
id: WBPhenotype:0000076

Axiom
annotated source: epithelial attachment variant
annotated property: IAO_0000115
annotated target: Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cuticle shedding defect
type: Class
subclass of: molt defect
IAO_0000115: Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement.
has narrow synonym: cuticle shedding abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000077

Axiom
annotated source: cuticle shedding defect
annotated property: IAO_0000115
annotated target: Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement.
has db xref: GO:0018996

seam cells stacked
type: Class
subclass of: epithelial morphology variant
IAO_0000115: The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells .
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000078

Axiom
annotated source: seam cells stacked
annotated property: IAO_0000115
annotated target: The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells .
has db xref: WB:WBPaper00003081

branched adult alae
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000402
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007832
subclass of: WBPhenotype_0001412
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000402
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007832
IAO_0000115: The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000079

Axiom
annotated source: branched adult alae
annotated property: IAO_0000115
annotated target: The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no anterior pharynx
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003733
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: anterior pharynx variant
subclass of: WBPhenotype_0001646
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003733
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack the anterior portion of the pharynx.
has broad synonym: Aph
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000080

Axiom
annotated source: no anterior pharynx
annotated property: IAO_0000115
annotated target: Animals lack the anterior portion of the pharynx.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

L1 arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000024
subclass of: early larval arrest
subclass of: WBPhenotype_0000751
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000024
IAO_0000115: The developmental program of the animals does not continue past the first larval stage (L1).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000081

Axiom
annotated source: L1 arrest
annotated property: IAO_0000115
annotated target: The developmental program of the animals does not continue past the first larval stage (L1).
has db xref: WB:WBPaper00003179
has db xref: WB:WBPerson2021

L2 arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000027
subclass of: early larval arrest
subclass of: WBPhenotype_0000752
subclass of: WBPhenotype_0001019
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000027
IAO_0000115: The developmental program of the animals does not continue past the second larval stage (L2).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000082

Axiom
annotated source: L2 arrest
annotated property: IAO_0000115
annotated target: The developmental program of the animals does not continue past the second larval stage (L2).
has db xref: WB:WBPaper00003179
has db xref: WB:WBPerson2021

L3 arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000035
subclass of: late larval arrest
subclass of: WBPhenotype_0000753
subclass of: WBPhenotype_0001019
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000035
IAO_0000115: The developmental program of the animals does not continue past the third larval stage (L3).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000083

Axiom
annotated source: L3 arrest
annotated property: IAO_0000115
annotated target: The developmental program of the animals does not continue past the third larval stage (L3).
has db xref: WB:WBPaper00004813
has db xref: WB:WBPerson2021

L4 arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000038
subclass of: late larval arrest
subclass of: WBPhenotype_0000754
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: during
      some values from: WBls_0000038
IAO_0000115: The developmental program of the animals does not continue past the fourth larval stage (L4).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000084

Axiom
annotated source: L4 arrest
annotated property: IAO_0000115
annotated target: The developmental program of the animals does not continue past the fourth larval stage (L4).
has db xref: WB:WBPaper00003179
has db xref: WB:WBPerson2021

swollen intestinal lumen
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
subclass of: WBPhenotype_0000710
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
IAO_0000115: The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000085

Axiom
annotated source: swollen intestinal lumen
annotated property: IAO_0000115
annotated target: The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema).
has db xref: WB:WBPaper00026641
has db xref: WB:WBPerson712

shrunken intestine
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000585
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
subclass of: WBPhenotype_0000710
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000585
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
IAO_0000115: Intestine is shrunken and may appear constricted.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000086

Axiom
annotated source: shrunken intestine
annotated property: IAO_0000115
annotated target: Intestine is shrunken and may appear constricted.
has db xref: WB:WBPaper00005941

body wall cell development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000815
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has narrow synonym: body wall cell development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body wall muscle cell development abnormal
id: WBPhenotype:0000087

Axiom
annotated source: body wall cell development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has db xref: WB:WBPerson2021

body muscle displaced
type: Class
subclass of: WBPhenotype_0000861
IAO_0000115: The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body wall muscle displaced
id: WBPhenotype:0000088

Axiom
annotated source: body muscle displaced
annotated property: IAO_0000115
annotated target: The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alpha amanitin resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_37415
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_37415
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000089

Axiom
annotated source: alpha amanitin resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

epidermis cuticle detached
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
subclass of: cuticle attachment variant
subclass of: epithelial attachment variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
IAO_0000115: Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: hypodermis detached from cuticle
id: WBPhenotype:0000090

Axiom
annotated source: epidermis cuticle detached
annotated property: IAO_0000115
annotated target: Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

epidermis muscle detached
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
subclass of: epithelial attachment variant
subclass of: muscle detached
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
IAO_0000115: The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: hypodermis detached from muscle
id: WBPhenotype:0000091

Axiom
annotated source: epidermis muscle detached
annotated property: IAO_0000115
annotated target: The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

intestinal cell proliferation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008283
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell proliferation variant
subclass of: cell physiology phenotype
subclass of: intestinal cell development variant
subclass of: WBPhenotype_0001093
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008283
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the processes that govern the expansion of intestinal cell populations compared to control.
has narrow synonym: intestinal cell proliferation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000092

Axiom
annotated source: intestinal cell proliferation variant
annotated property: IAO_0000115
annotated target: Any variation in the processes that govern the expansion of intestinal cell populations compared to control.
has db xref: WB:WBPerson2021

lineage variant
type: Class
subclass of: cell development variant
IAO_0000115: The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.
has broad synonym: Lin
has narrow synonym: lineage abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000093
in subset: phenotype slim wb

Axiom
annotated source: lineage variant
annotated property: IAO_0000115
annotated target: The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.
has db xref: WB:WBPerson2021

anus development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas).
has narrow synonym: anus development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000094

Axiom
annotated source: anus development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

M lineage variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: WBPhenotype_0000825
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
has narrow synonym: M lineage abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000095

Axiom
annotated source: M lineage variant
annotated property: IAO_0000115
annotated target: The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
has db xref: WB:WBPerson2021

cloacal development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: WBPhenotype_0000930
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas).
has narrow synonym: cloacal development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000096

Axiom
annotated source: cloacal development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

AB lineage variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: WBPhenotype_0000824
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
has narrow synonym: AB lineage abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000097

Axiom
annotated source: AB lineage variant
annotated property: IAO_0000115
annotated target: The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
has db xref: WB:WBPaper00001584
has db xref: WB:WBPerson2021

pharyngeal intestinal valve development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
has narrow synonym: pharyngeal intestinal valve development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000098

Axiom
annotated source: pharyngeal intestinal valve development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

P lineages variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: WBPhenotype_0000825
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals.
has narrow synonym: P lineages abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000099

Axiom
annotated source: P lineages variant
annotated property: IAO_0000115
annotated target: The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals.
has db xref: WB:WBPerson2021

cell UV response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034644
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell stress response variant
subclass of: organism UV response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034644
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
has narrow synonym: cell UV response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000100

Axiom
annotated source: cell UV response variant
annotated property: IAO_0000115
annotated target: Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
has db xref: WB:WBPerson557

UV induced apoptosis increased
type: Class
subclass of: cell UV response variant
subclass of: apoptosis increased
IAO_0000115: Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000101

Axiom
annotated source: UV induced apoptosis increased
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control.
has db xref: WB:WBPerson712

presynaptic vesicle cluster variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0097091
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000846
subclass of: WBPhenotype_0001321
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0097091
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals.
has narrow synonym: presynaptic vesicle cluster abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: synaptic vesicle cluster abnormal
id: WBPhenotype:0000102

Axiom
annotated source: presynaptic vesicle cluster variant
annotated property: IAO_0000115
annotated target: Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals.
has db xref: WB:WBPaper00027305

gut granule development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: intestinal cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
has narrow synonym: gut granule development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000103

Axiom
annotated source: gut granule development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell polarity variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007163
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007163
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell.
has narrow synonym: cell polarity abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000104
in subset: phenotype slim wb

Axiom
annotated source: cell polarity variant
annotated property: IAO_0000115
annotated target: Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell.
has db xref: WB:WBPaper00031356
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson712

oocyte meiotic maturation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1903537
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: meiotic progression during oogenesis variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1903537
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.
has broad synonym: Oma
has narrow synonym: oocyte meiotic maturation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000105

Axiom
annotated source: oocyte meiotic maturation variant
annotated property: IAO_0000115
annotated target: Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.
has db xref: GO:0001556
has db xref: WB:WBPaper00026997
has db xref: WB:WBPerson2021

inhibition of oocyte maturation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1904145
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: oocyte meiotic maturation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1904145
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals.
has narrow synonym: inhibition of oocyte maturation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000106

Axiom
annotated source: inhibition of oocyte maturation variant
annotated property: IAO_0000115
annotated target: Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals.
has db xref: WB:WBPaper00003371
has db xref: WB:WBPaper00026997
has db xref: WB:WBPerson2021

inhibition of ovulation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060280
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: ovulation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060280
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
has narrow synonym: inhibition of ovulation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000107

Axiom
annotated source: inhibition of ovulation variant
annotated property: IAO_0000115
annotated target: Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
has db xref: GO:0060280
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete severe dumpy
type: Class
IAO_0000115: OBSOLETE.
consider: dumpy
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000108
deprecated: true

obsolete moderate dumpy
type: Class
IAO_0000115: OBSOLETE.
consider: dumpy
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000109
deprecated: true

obsolete slightly dumpy
type: Class
IAO_0000115: OBSOLETE.
consider: dumpy
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000110
deprecated: true

pattern of gene expression variant
type: Class
subclass of: WBPhenotype_0000717
IAO_0000115: Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals.
has narrow synonym: pattern of gene expression abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000111

Axiom
annotated source: pattern of gene expression variant
annotated property: IAO_0000115
annotated target: Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals.
has db xref: WB:WBPerson2021

protein expression variant
type: Class
subclass of: WBPhenotype_0000717
IAO_0000115: Variations in the biogenesis and stability of protein molecules compared to control.
has narrow synonym: protein expression abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000112

Axiom
annotated source: protein expression variant
annotated property: IAO_0000115
annotated target: Variations in the biogenesis and stability of protein molecules compared to control.
has db xref: WB:WBPerson2021

RNA expression variant
type: Class
subclass of: WBPhenotype_0000717
IAO_0000115: Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control.
has narrow synonym: RNA expression abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000113

Axiom
annotated source: RNA expression variant
annotated property: IAO_0000115
annotated target: Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control.
has db xref: WB:WBPerson2021

mRNA expression variant
type: Class
subclass of: RNA expression variant
IAO_0000115: Variations in the biogenesis and stability of messenger RNA molecules compared to control.
has narrow synonym: mRNA expression abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000114

Axiom
annotated source: mRNA expression variant
annotated property: IAO_0000115
annotated target: Variations in the biogenesis and stability of messenger RNA molecules compared to control.
has db xref: GO:0050684
has db xref: WB:WBPerson2021

anterior pharynx variant
type: Class
subclass of: pharyngeal development variant
IAO_0000115: Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb).
has narrow synonym: anterior pharynx abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000115

Axiom
annotated source: anterior pharynx variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

mid larval lethal
type: Class
subclass of: larval lethal
IAO_0000115: Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000116

Axiom
annotated source: mid larval lethal
annotated property: IAO_0000115
annotated target: Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle.
has db xref: WB:WBPerson2021

L1 lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000024
subclass of: early larval lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000024
IAO_0000115: Animals die at the L1 stage of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000117

Axiom
annotated source: L1 lethal
annotated property: IAO_0000115
annotated target: Animals die at the L1 stage of the life cycle.
has db xref: WB:WBPerson2021

L2 lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000027
subclass of: early larval lethal
subclass of: mid larval lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000027
IAO_0000115: L2 lethal: Animals die at the L2 stage of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000118

Axiom
annotated source: L2 lethal
annotated property: IAO_0000115
annotated target: L2 lethal: Animals die at the L2 stage of the life cycle.
has db xref: WB:WBPerson2021

protein expression increased
type: Class
subclass of: WBPhenotype_0001400
IAO_0000115: Any change that results in higher than normal levels of protein expression compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000119

Axiom
annotated source: protein expression increased
annotated property: IAO_0000115
annotated target: Any change that results in higher than normal levels of protein expression compared to control animals.
has db xref: WB:WBPerson557

protein expression reduced
type: Class
subclass of: WBPhenotype_0001400
IAO_0000115: Any change that results in lower than normal levels of protein expression compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000120

Axiom
annotated source: protein expression reduced
annotated property: IAO_0000115
annotated target: Any change that results in lower than normal levels of protein expression compared to control animals.
has db xref: WB:kmva

translation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006412
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: protein expression variant
subclass of: WBPhenotype_0001644
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006412
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control.
has narrow synonym: translation abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: protein synthesis abnormal
id: WBPhenotype:0000121

Axiom
annotated source: translation variant
annotated property: IAO_0000115
annotated target: Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control.
has db xref: GO:0006412
has db xref: WB:WBPerson2021

post translational processing variant
type: Class
subclass of: organism metabolism processing variant
IAO_0000115: Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control.
has narrow synonym: post translational processing abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: protein processing variant
id: WBPhenotype:0000122

Axiom
annotated source: post translational processing variant
annotated property: IAO_0000115
annotated target: Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control.
has db xref: GO:0016485
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

enzyme expression level reduced
type: Class
subclass of: protein expression reduced
IAO_0000115: Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000123

Axiom
annotated source: enzyme expression level reduced
annotated property: IAO_0000115
annotated target: Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals.
has db xref: WB:WBPerson2021

enzyme activity reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0003824
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000727
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0003824
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000124

Axiom
annotated source: enzyme activity reduced
annotated property: IAO_0000115
annotated target: Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

enzyme activity increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0003824
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000727
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0003824
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000125

Axiom
annotated source: enzyme activity increased
annotated property: IAO_0000115
annotated target: Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

general pace of development defective early emb
type: Class
subclass of: general pace of development variant
IAO_0000115: Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals.
has broad synonym: Emb
has narrow synonym: general pace of development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000126

Axiom
annotated source: general pace of development defective early emb
annotated property: IAO_0000115
annotated target: Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals.
has db xref: WB:cab
has db xref: WB:cgc7141

dauer recovery variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043054
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: dauer development phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043054
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Characteristic exit from the dauer stage is altered compared to control animals.
has narrow synonym: dauer recovery abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000127

Axiom
annotated source: dauer recovery variant
annotated property: IAO_0000115
annotated target: Characteristic exit from the dauer stage is altered compared to control animals.
has db xref: WB:cab

temperature induced dauer formation increased
type: Class
subclass of: temperature induced dauer formation variant
IAO_0000115: Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals.
has broad synonym: Hid
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000128

Axiom
annotated source: temperature induced dauer formation increased
annotated property: IAO_0000115
annotated target: Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals.
has db xref: WB:cgc424

temperature induced dauer formation defective
type: Class
subclass of: dauer defective
subclass of: temperature induced dauer formation variant
IAO_0000115: Animals do not enter dauer at a temperature that induces dauer formation in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000129

Axiom
annotated source: temperature induced dauer formation defective
annotated property: IAO_0000115
annotated target: Animals do not enter dauer at a temperature that induces dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pheromone induced dauer formation enhanced
type: Class
subclass of: pheromone induced dauer formation variant
IAO_0000115: Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000130

Axiom
annotated source: pheromone induced dauer formation enhanced
annotated property: IAO_0000115
annotated target: Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pheromone induced dauer formation defective
type: Class
subclass of: dauer defective
subclass of: pheromone induced dauer formation variant
IAO_0000115: Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals.
has broad synonym: Phd
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000131

Axiom
annotated source: pheromone induced dauer formation defective
annotated property: IAO_0000115
annotated target: Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pheromone induced dauer formation variant
type: Class
subclass of: WBPhenotype_0001539
IAO_0000115: Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals.
has narrow synonym: pheromone induced dauer formation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000132

Axiom
annotated source: pheromone induced dauer formation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

expression lipogenic enzyme reduced
type: Class
subclass of: enzyme expression level reduced
IAO_0000115: The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000133

Axiom
annotated source: expression lipogenic enzyme reduced
annotated property: IAO_0000115
annotated target: The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals.
has db xref: WB:WBPerson2021

gene expression level reduced
type: Class
subclass of: WBPhenotype_0002575
IAO_0000115: Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000134

Axiom
annotated source: gene expression level reduced
annotated property: IAO_0000115
annotated target: Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals.
has db xref: WB:WBPerson2021

gene expression level high
type: Class
subclass of: WBPhenotype_0002575
IAO_0000115: Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000135

Axiom
annotated source: gene expression level high
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals.
has db xref: WB:WBPerson2021

mRNA levels increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_33699
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: mRNA expression variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_33699
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit elevated levels of messenger RNA compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000136

Axiom
annotated source: mRNA levels increased
annotated property: IAO_0000115
annotated target: Animals exhibit elevated levels of messenger RNA compared to control.
has db xref: WB:WBPaper00033456
has db xref: WB:WBPerson2021

mRNA levels reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001997
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_33699
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: mRNA expression variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001997
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_33699
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit decreased levels of messenger RNA compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000137

Axiom
annotated source: mRNA levels reduced
annotated property: IAO_0000115
annotated target: Animals exhibit decreased levels of messenger RNA compared to control.
has db xref: WB:WBPaper00033456
has db xref: WB:WBPerson2021

lipid composition variant
type: Class
subclass of: WBPhenotype_0000725
IAO_0000115: The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals.
has narrow synonym: lipid composition abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: fat composition abnormal
has related synonym: fatty acid composition abnormal
id: WBPhenotype:0000138

Axiom
annotated source: lipid composition variant
annotated property: IAO_0000115
annotated target: The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals.
has db xref: WB:WBPerson712

stress induced lethality variant
type: Class
subclass of: organism stress response variant
IAO_0000115: Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals.
has narrow synonym: stress induced lethality abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000139

Axiom
annotated source: stress induced lethality variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

stress induced arrest variant
type: Class
subclass of: organism stress response variant
IAO_0000115: Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals.
has narrow synonym: stress induced arrest abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000140

Axiom
annotated source: stress induced arrest variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

stress induced lethality increased
type: Class
subclass of: stress induced lethality variant
IAO_0000115: Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000141

Axiom
annotated source: stress induced lethality increased
annotated property: IAO_0000115
annotated target: Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell stress response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0033554
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: cell homeostasis metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0033554
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
has narrow synonym: cell stress response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000142

Axiom
annotated source: cell stress response variant
annotated property: IAO_0000115
annotated target: Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
has db xref: GO:0033554
has db xref: WB:WBPerson2021

organism UV response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009411
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: WBPhenotype_0001897
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009411
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
has narrow synonym: organism UV response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000143

Axiom
annotated source: organism UV response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
has db xref: WB:WBPerson557

pathogen induced cell death increased
type: Class
subclass of: cell stress response variant
subclass of: WBPhenotype_0001269
IAO_0000115: Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000144

Axiom
annotated source: pathogen induced cell death increased
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
has db xref: WB:WBPerson712

fertility phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000274
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: reproductive system physiology variant
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000274
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control.
has exact synonym: fertility variant
has narrow synonym: fertility abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000145
in subset: phenotype slim wb

Axiom
annotated source: fertility phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control.
has db xref: GO:0000003
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism temperature response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009266
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0009266
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span.
has narrow synonym: organism temperature response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000146

Axiom
annotated source: organism temperature response variant
annotated property: IAO_0000115
annotated target: Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span.
has db xref: WB:WBPerson712

organism starvation response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042594
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042594
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control.
has narrow synonym: organism starvation response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000147

Axiom
annotated source: organism starvation response variant
annotated property: IAO_0000115
annotated target: Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control.
has db xref: GO:0042594
has db xref: WB:WBPerson2021

starvation induced dauer formation variant
type: Class
subclass of: organism starvation response variant
subclass of: WBPhenotype_0001539
IAO_0000115: Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals.
has narrow synonym: starvation induced dauer formation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000148

Axiom
annotated source: starvation induced dauer formation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

starvation induced dauer formation increased
type: Class
subclass of: starvation induced dauer formation variant
IAO_0000115: Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000149

Axiom
annotated source: starvation induced dauer formation increased
annotated property: IAO_0000115
annotated target: Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

starvation induced dauer formation defective
type: Class
subclass of: dauer defective
subclass of: starvation induced dauer formation variant
IAO_0000115: Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000150

Axiom
annotated source: starvation induced dauer formation defective
annotated property: IAO_0000115
annotated target: Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

anterior pharynx extra cells
type: Class
subclass of: anterior pharynx variant
subclass of: WBPhenotype_0002175
IAO_0000115: Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere.
has broad synonym: Apx
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000151

Axiom
annotated source: anterior pharynx extra cells
annotated property: IAO_0000115
annotated target: Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere.
has db xref: WB:WBPaper00001930
has db xref: WB:WBPerson2021

no cleavage furrow first division early emb
type: Class
subclass of: WBPhenotype_0001129
IAO_0000115: One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000152

Axiom
annotated source: no cleavage furrow first division early emb
annotated property: IAO_0000115
annotated target: One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
has db xref: GO:0032154
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body wall muscle contraction abnormal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0006936
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body behavior variant
subclass of: muscle system physiology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0006936
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
has exact synonym: body wall contraction variant
has narrow synonym: body wall contraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000153

Axiom
annotated source: body wall muscle contraction abnormal
annotated property: IAO_0000115
annotated target: Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
has db xref: WB:WBPaper00032190
has db xref: WB:WBPerson712

reduced brood size
type: Class
subclass of: brood size variant
IAO_0000115: The characteristic number of offspring produced is lower compared to that of control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000154

Axiom
annotated source: reduced brood size
annotated property: IAO_0000115
annotated target: The characteristic number of offspring produced is lower compared to that of control animals.
has db xref: WB:WBPerson557

cell polarity reversed
type: Class
subclass of: cell polarity variant
IAO_0000115: Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000155

Axiom
annotated source: cell polarity reversed
annotated property: IAO_0000115
annotated target: Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped.
has db xref: WB:WBPaper00031356
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson712

body wall muscle contraction interval during defecation abnormal
type: Class
subclass of: defecation contraction variant
IAO_0000115: Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol.
has narrow synonym: body wall contraction interval abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body wall muscle contraction interval abnormal
id: WBPhenotype:0000156

Axiom
annotated source: body wall muscle contraction interval during defecation abnormal
annotated property: IAO_0000115
annotated target: Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

posterior body wall contraction defecation cycle variant
type: Class
subclass of: defecation contraction variant
IAO_0000115: Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals.
has broad synonym: pBoc
has narrow synonym: posterior body wall contraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: posterior body contraction abnormal
has related synonym: posterior body wall contraction defective
id: WBPhenotype:0000157

Axiom
annotated source: posterior body wall contraction defecation cycle variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals.
has db xref: WB:WBPaper00031426
has db xref: WB:WBPerson712

obsolete posterior body wall shortened interval
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: short defecation cycle
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000158
deprecated: true

obsolete dauer arrest variant
type: Class
IAO_0000115: OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas).
IAO_0100001: dauer development phenotype
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000159
deprecated: true

Axiom
annotated source: obsolete dauer arrest variant
annotated property: IAO_0000115
annotated target: OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cleavage furrow not discrete early emb
type: Class
subclass of: WBPhenotype_0001129
IAO_0000115: Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000160

Axiom
annotated source: cleavage furrow not discrete early emb
annotated property: IAO_0000115
annotated target: Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
has db xref: GO:0032154
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nuclear rotation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001599
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005634
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000749
subclass of: WBPhenotype_0001028
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001599
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005634
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control.
has narrow synonym: nuclear rotation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000161

Axiom
annotated source: nuclear rotation variant
annotated property: IAO_0000115
annotated target: Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control.
has db xref: GO:0035047
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pale larva
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000328
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
subclass of: WBPhenotype_0000890
subclass of: WBPhenotype_0001261
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000328
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
IAO_0000115: Larva show deficiencies in chroma resulting in increased translucency.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: translucent
id: WBPhenotype:0000162

Axiom
annotated source: pale larva
annotated property: IAO_0000115
annotated target: Larva show deficiencies in chroma resulting in increased translucency.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

clear larva
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000964
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
subclass of: WBPhenotype_0000890
subclass of: WBPhenotype_0001010
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000964
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
IAO_0000115: Larva appear unusually transparent when compared to control.
has broad synonym: Clr
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: transparent
id: WBPhenotype:0000163

Axiom
annotated source: clear larva
annotated property: IAO_0000115
annotated target: Larva appear unusually transparent when compared to control.
has db xref: WB:WBPerson557

thin
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000592
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
subclass of: WBPhenotype_0001727
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000592
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
IAO_0000115: Animals exhibit a reduced girth compared to a control animal of the same developmental stage.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: decreased girth
has related synonym: slim
id: WBPhenotype:0000164

Axiom
annotated source: thin
annotated property: IAO_0000115
annotated target: Animals exhibit a reduced girth compared to a control animal of the same developmental stage.
has db xref: WB:WBPerson712

cell fusion variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000768
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000768
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.
has narrow synonym: cell fusion abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000165
in subset: phenotype slim wb

Axiom
annotated source: cell fusion variant
annotated property: IAO_0000115
annotated target: Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.
has db xref: GO:0000768
has db xref: GO:0045026
has db xref: WB:WBPaper00005122
has db xref: WB:WBPerson2021

seam cell fusion variant
type: Class
subclass of: cell fusion variant
IAO_0000115: Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.
has narrow synonym: seam cell fusion abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000166

Axiom
annotated source: seam cell fusion variant
annotated property: IAO_0000115
annotated target: Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

precocious seam cell fusion
type: Class
subclass of: seam cell fusion variant
subclass of: WBPhenotype_0001433
IAO_0000115: Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000167

Axiom
annotated source: precocious seam cell fusion
annotated property: IAO_0000115
annotated target: Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alae secretion variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0046903
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell secretion variant
subclass of: epithelial system physiology variant
subclass of: WBPhenotype_0001210
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0046903
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas).
has narrow synonym: alae secretion abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: alae formation variant
id: WBPhenotype:0000168

Axiom
annotated source: alae secretion variant
annotated property: IAO_0000115
annotated target: Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas).
has db xref: WB:WBPaper00004833
has db xref: WB:WBPaper00025242
has db xref: WB:WBPerson2021

early exit cell cycle
type: Class
subclass of: WBPhenotype_0001995
IAO_0000115: Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000169

Axiom
annotated source: early exit cell cycle
annotated property: IAO_0000115
annotated target: Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells.
has db xref: GO:0010458
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

precocious alae
type: Class
subclass of: alae secretion variant
subclass of: precocious heterochronic variations
IAO_0000115: Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000170

Axiom
annotated source: precocious alae
annotated property: IAO_0000115
annotated target: Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage.
has db xref: WB:cab
has db xref: pmid:3428573

cell proliferation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any aberrancy in the processes that govern expansion of cell populations compared to control animals.
has narrow synonym: cell proliferation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000171
in subset: phenotype slim wb

Axiom
annotated source: cell proliferation variant
annotated property: IAO_0000115
annotated target: Any aberrancy in the processes that govern expansion of cell populations compared to control animals.
has db xref: GO:0008283
has db xref: WB:WBPerson2021

cell proliferation increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell proliferation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000172

Axiom
annotated source: cell proliferation increased
annotated property: IAO_0000115
annotated target: The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased.
has db xref: WB:WBPerson2021

cell proliferation reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002052
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell proliferation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002052
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000173

Axiom
annotated source: cell proliferation reduced
annotated property: IAO_0000115
annotated target: The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased.
has db xref: WB:WBPerson2021

basal lamina development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: epithelial system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas).
has narrow synonym: basal lamina development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000174

Axiom
annotated source: basal lamina development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hypercontracted
type: Class
subclass of: body posture variant
IAO_0000115: Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000175

Axiom
annotated source: hypercontracted
annotated property: IAO_0000115
annotated target: Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body.
has db xref: WB:WBPerson363

satiety behavior variant
type: Class
subclass of: feeding behavior variant
IAO_0000115: Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated.
has narrow synonym: satiety behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000176

Axiom
annotated source: satiety behavior variant
annotated property: IAO_0000115
annotated target: Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

acetylcholinesterase reduced
type: Class
subclass of: enzyme activity reduced
IAO_0000115: Any variation that results in a decrease of acetylcholine esterase levels, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000177

Axiom
annotated source: acetylcholinesterase reduced
annotated property: IAO_0000115
annotated target: Any variation that results in a decrease of acetylcholine esterase levels, compared to control.
has db xref: WB:WBPaper00024452
has db xref: WB:WBPerson2021

cell degeneration
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000639
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell morphology variant
subclass of: WBPhenotype_0000729
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000639
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000178

Axiom
annotated source: cell degeneration
annotated property: IAO_0000115
annotated target: Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
has db xref: WB:WBPerson712

neuron degeneration
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000639
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003679
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell degeneration
subclass of: WBPhenotype_0000905
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000639
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003679
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000179

Axiom
annotated source: neuron degeneration
annotated property: IAO_0000115
annotated target: Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles.
has db xref: WB:WBPerson712
has db xref: WB:WBperson557

axon morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030424
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001398
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030424
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals.
has narrow synonym: axon morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000180

Axiom
annotated source: axon morphology variant
annotated property: IAO_0000115
annotated target: Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals.
has db xref: GO:0030424
has db xref: WB:WBPaper00005236
has db xref: WB:WBPerson712

axon trajectory variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000133
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030424
subclass of: axon morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000133
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030424
IAO_0000115: Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals.
has narrow synonym: axon trajectory abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000181

Axiom
annotated source: axon trajectory variant
annotated property: IAO_0000115
annotated target: Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals.
has db xref: WB:WBPaper00001105
has db xref: WB:WBPerson712

apoptosis reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002052
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000730
subclass of: WBPhenotype_0002620
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002052
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000182

Axiom
annotated source: apoptosis reduced
annotated property: IAO_0000115
annotated target: Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
has db xref: GO:0043065
has db xref: WB:WBPerson2021

apoptosis increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000730
subclass of: WBPhenotype_0002619
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000183

Axiom
annotated source: apoptosis increased
annotated property: IAO_0000115
annotated target: Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
has db xref: GO:0043066
has db xref: WB:WBPerson2021

apoptosis fails to occur
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: apoptosis reduced
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000184

Axiom
annotated source: apoptosis fails to occur
annotated property: IAO_0000115
annotated target: Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
has db xref: WB:WBPerson712

apoptosis protracted
type: Class
subclass of: WBPhenotype_0000730
IAO_0000115: Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000185

Axiom
annotated source: apoptosis protracted
annotated property: IAO_0000115
annotated target: Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells.
has db xref: WB:WBPerson712

oogenesis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048599
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000812
subclass of: WBPhenotype_0000894
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048599
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
has alternative id: WBPhenotype:0000896
has exact synonym: oocyte germ cell differentiation abnormal
has narrow synonym: oogenesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: oocyte development abnormal
id: WBPhenotype:0000186

Axiom
annotated source: oogenesis variant
annotated property: IAO_0000115
annotated target: Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
has db xref: GO:0048477
has db xref: WB:WBPerson2021

egg round
type: Class
subclass of: egg shape variable
IAO_0000115: The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000187

Axiom
annotated source: egg round
annotated property: IAO_0000115
annotated target: The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

gonad arm morphology variant
type: Class
subclass of: WBPhenotype_0000977
IAO_0000115: Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad.
has narrow synonym: gonad arm morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000188

Axiom
annotated source: gonad arm morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hypodermis disorganized
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
subclass of: epithelial morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005733
IAO_0000115: Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000189

Axiom
annotated source: hypodermis disorganized
annotated property: IAO_0000115
annotated target: Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body.
has db xref: WB:WBPaper00027006
has db xref: WB:WBPerson2021

no dauer recovery
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043054
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: dauer recovery variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043054
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000190

Axiom
annotated source: no dauer recovery
annotated property: IAO_0000115
annotated target: Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development.
has db xref: GO:0043054
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism crowding response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0090664
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0090664
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas).
has narrow synonym: organism crowding response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000191

Axiom
annotated source: organism crowding response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

constitutive enzyme activity
type: Class
subclass of: enzyme activity increased
IAO_0000115: Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000192

Axiom
annotated source: constitutive enzyme activity
annotated property: IAO_0000115
annotated target: Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dominant negative enzyme
type: Class
subclass of: WBPhenotype_0000727
IAO_0000115: Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000193

Axiom
annotated source: dominant negative enzyme
annotated property: IAO_0000115
annotated target: Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype.
has db xref: WB:WBPerson2021

first polar body position variant
type: Class
subclass of: WBPhenotype_0000775
IAO_0000115: Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals.
has narrow synonym: first polar body position abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000194

Axiom
annotated source: first polar body position variant
annotated property: IAO_0000115
annotated target: Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

distal tip cell migration variant
type: Class
subclass of: cell migration variant
IAO_0000115: Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern.
has narrow synonym: distal tip cell migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: DTC migration abnormal
id: WBPhenotype:0000195

Axiom
annotated source: distal tip cell migration variant
annotated property: IAO_0000115
annotated target: Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern.
has db xref: GO:0040039
has db xref: WB:WBPaper00003598
has db xref: WB:WBPerson2021

distal tip cell morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006865
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0002108
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006865
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The morphological appearance of distal tip cells is varied compared to control animals.
has narrow synonym: distal tip cell morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000196

Axiom
annotated source: distal tip cell morphology variant
annotated property: IAO_0000115
annotated target: The morphological appearance of distal tip cells is varied compared to control animals.
has db xref: WB:cab

cell induction variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0031129
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell fate specification variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0031129
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling).
has narrow synonym: cell induction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000197

Axiom
annotated source: cell induction variant
annotated property: IAO_0000115
annotated target: Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling).
has db xref: GO:0031128
has db xref: WB:WBPerson2021

obsolete vulval cell induction abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: WBPhenotype_0001272
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000198
deprecated: true

male tail sensory ray development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000930
subclass of: WBPhenotype_0001008
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals.
has narrow synonym: male tail sensory ray development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000199

Axiom
annotated source: male tail sensory ray development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pericellular component development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: development phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control.
has narrow synonym: pericellular component development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000200
in subset: phenotype slim wb

Axiom
annotated source: pericellular component development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cuticle development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042335
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: pericellular component development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042335
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas).
has narrow synonym: cuticle development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000201

Axiom
annotated source: cuticle development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alae variant
type: Class
subclass of: cuticle development variant
IAO_0000115: Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas).
has narrow synonym: alae abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000202

Axiom
annotated source: alae variant
annotated property: IAO_0000115
annotated target: Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

odorant adaptation variant
type: Class
subclass of: WBPhenotype_0001048
IAO_0000115: Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals.
has narrow synonym: odorant adaptation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000203

Axiom
annotated source: odorant adaptation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals.
has db xref: WB:WBPerson2021

anterior body contraction defecation cycle variant
type: Class
subclass of: WBPhenotype_0001476
IAO_0000115: Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step.
has broad synonym: aBoc
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: anterior body contraction abnormal
has related synonym: anterior body contraction defective
id: WBPhenotype:0000204

Axiom
annotated source: anterior body contraction defecation cycle variant
annotated property: IAO_0000115
annotated target: Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step.
has db xref: WB:WBPerson2021

expulsion variant
type: Class
subclass of: defecation contraction variant
IAO_0000115: Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
has narrow synonym: expulsion abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Exp
id: WBPhenotype:0000205

Axiom
annotated source: expulsion variant
annotated property: IAO_0000115
annotated target: Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

autosomal nondisjunction meiosis
type: Class
subclass of: WBPhenotype_0001174
IAO_0000115: A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000206

Axiom
annotated source: autosomal nondisjunction meiosis
annotated property: IAO_0000115
annotated target: A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog.
has db xref: GO:0045143
has db xref: WB:WBPerson712

defecation cycle variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035882
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: defecation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035882
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control .
has narrow synonym: defecation cycle abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Dec
id: WBPhenotype:0000207

Axiom
annotated source: defecation cycle variant
annotated property: IAO_0000115
annotated target: Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control .
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

long defecation cycle
type: Class
subclass of: defecation cycle variant
IAO_0000115: The mean time between the onset of the defecation motor program is greater than that observed for control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Dec-l
has related synonym: reduced rate of defecation
id: WBPhenotype:0000208

Axiom
annotated source: long defecation cycle
annotated property: IAO_0000115
annotated target: The mean time between the onset of the defecation motor program is greater than that observed for control animals.
has db xref: WB:WBPaper00002315
has db xref: WB:WBPaper00031896
has db xref: WB:WBPerson712

short defecation cycle
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: defecation cycle variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The mean time between the onset of the defecation motor program is shorter than that observed for control animals.
has exact synonym: posterior body wall shortened interval
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Dec-s
has related synonym: fast Dec
has related synonym: increased rate of defecation
id: WBPhenotype:0000209

Axiom
annotated source: short defecation cycle
annotated property: IAO_0000115
annotated target: The mean time between the onset of the defecation motor program is shorter than that observed for control animals.
has db xref: WB:WBPaper00002315
has db xref: WB:WBPaper00031896
has db xref: WB:WBPerson712

defecation contraction variant
type: Class
subclass of: defecation variant
IAO_0000115: Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
has narrow synonym: defecation contraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000210

Axiom
annotated source: defecation contraction variant
annotated property: IAO_0000115
annotated target: Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

defecation contraction asynchronous
type: Class
subclass of: defecation contraction variant
IAO_0000115: The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: defecation contraction mistimed
id: WBPhenotype:0000211

Axiom
annotated source: defecation contraction asynchronous
annotated property: IAO_0000115
annotated target: The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body constriction
type: Class
subclass of: body morphology variant
IAO_0000115: Animals contain body regions that are more narrow or drawn together than adjacent body regions.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000212

Axiom
annotated source: body constriction
annotated property: IAO_0000115
annotated target: Animals contain body regions that are more narrow or drawn together than adjacent body regions.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

zygotic development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control.
has narrow synonym: zygotic development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000213

Axiom
annotated source: zygotic development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alpha amanitin hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_37415
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_37415
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000214

Axiom
annotated source: alpha amanitin hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

no germ line
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005784
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000812
subclass of: WBPhenotype_0002556
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005784
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
has exact synonym: no germline
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000215

Axiom
annotated source: no germ line
annotated property: IAO_0000115
annotated target: Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
has db xref: WB:WBPaper00001477
has db xref: WB:WBPerson2021

cell fate specification variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0001708
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0001708
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the processes that govern acquisition of particular cell fates compared to control animals.
has narrow synonym: cell fate specification abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000216
in subset: phenotype slim wb

Axiom
annotated source: cell fate specification variant
annotated property: IAO_0000115
annotated target: Any variation in the processes that govern acquisition of particular cell fates compared to control animals.
has db xref: WB:kmva

prolonged pharyngeal contraction
type: Class
subclass of: WBPhenotype_0000980
IAO_0000115: The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000217

Axiom
annotated source: prolonged pharyngeal contraction
annotated property: IAO_0000115
annotated target: The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

vulval cell induction increased
type: Class
subclass of: WBPhenotype_0001272
IAO_0000115: An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals.
has broad synonym: Hin
has narrow synonym: overinduced
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000218

Axiom
annotated source: vulval cell induction increased
annotated property: IAO_0000115
annotated target: An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals.
has db xref: WB:WBPerson2021

vulval cell induction reduced
type: Class
subclass of: WBPhenotype_0001272
IAO_0000115: Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals.
has narrow synonym: underinduced
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000219

Axiom
annotated source: vulval cell induction reduced
annotated property: IAO_0000115
annotated target: Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals.
has db xref: WB:WBPerson2021

vulva cell fate specification variant
type: Class
subclass of: cell fate specification variant
subclass of: vulva development variant
IAO_0000115: Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals.
has narrow synonym: vulva cell fate specification abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000220

Axiom
annotated source: vulva cell fate specification variant
annotated property: IAO_0000115
annotated target: Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals.
has db xref: WB:WBPerson2021

neurotransmitter metabolism variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042133
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism metabolism processing variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042133
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
has narrow synonym: neurotransmitter metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000221

Axiom
annotated source: neurotransmitter metabolism variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
has db xref: GO:0042133
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

serotonin metabolism variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042428
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: neurotransmitter metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042428
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control.
has narrow synonym: serotonin metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000222

Axiom
annotated source: serotonin metabolism variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control.
has db xref: GO:0042428
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

acetylcholine metabolism variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008291
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: neurotransmitter metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008291
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline.
has narrow synonym: acetylcholine metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000223

Axiom
annotated source: acetylcholine metabolism variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline.
has db xref: GO:0008291
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

serotonin deficient
type: Class
subclass of: serotonin metabolism variant
IAO_0000115: Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000224

Axiom
annotated source: serotonin deficient
annotated property: IAO_0000115
annotated target: Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity.
has db xref: WB:WBPerson712

serotonin synthesis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042427
subclass of: serotonin metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042427
IAO_0000115: Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000225

Axiom
annotated source: serotonin synthesis defective
annotated property: IAO_0000115
annotated target: Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin.
has db xref: GO:0042427
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

serotonin catabolism defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042429
subclass of: serotonin metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042429
IAO_0000115: Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000226

Axiom
annotated source: serotonin catabolism defective
annotated property: IAO_0000115
annotated target: Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter.
has db xref: GO:0042429
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

male turning defective
type: Class
subclass of: WBPhenotype_0004006
IAO_0000115: The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail.
has narrow synonym: male turning abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000227

Axiom
annotated source: male turning defective
annotated property: IAO_0000115
annotated target: The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail.
has db xref: GO:0034607
has db xref: WB:WBPaper00000392
has db xref: WB:WBPaper00002109

spontaneous mutation rate increased
type: Class
subclass of: organism homeostasis metabolism variant
IAO_0000115: Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000228

Axiom
annotated source: spontaneous mutation rate increased
annotated property: IAO_0000115
annotated target: Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
has db xref: WB:WBPaper00000565
has db xref: WB:WBPerson712

small
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000587
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001726
subclass of: WBPhenotype_0001727
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000587
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals are shorter and thinner than control animals at the same developmental stage.
has exact synonym: body size reduced
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Sma
id: WBPhenotype:0000229

Axiom
annotated source: small
annotated property: IAO_0000115
annotated target: Animals are shorter and thinner than control animals at the same developmental stage.
has db xref: WB:cab
has db xref: WB:cgc31

tail withered
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000585
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
subclass of: tail morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000585
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
IAO_0000115: The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Wit
id: WBPhenotype:0000230

Axiom
annotated source: tail withered
annotated property: IAO_0000115
annotated target: The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons.
has db xref: WB:WBPaper00002795
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body size variant
type: Class
subclass of: body morphology variant
IAO_0000115: Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage.
has narrow synonym: body size abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000231
comment: PATO:0000117.

Axiom
annotated source: body size variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage.
has db xref: WB:WBPerson712

CAN cell migration variant
type: Class
subclass of: WBPhenotype_0001520
IAO_0000115: Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo.
has narrow synonym: CAN cell migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000232

Axiom
annotated source: CAN cell migration variant
annotated property: IAO_0000115
annotated target: Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo.
has db xref: WB:WBPaper00002795
has db xref: WB:WBPerson2021

dopamine metabolism variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042417
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: neurotransmitter metabolism variant
subclass of: WBPhenotype_0001518
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042417
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control.
has narrow synonym: dopamine metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000233

Axiom
annotated source: dopamine metabolism variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control.
has db xref: GO:0042417
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

dopamine deficient
type: Class
subclass of: dopamine metabolism variant
IAO_0000115: Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: dopamine levels decreased
id: WBPhenotype:0000234

Axiom
annotated source: dopamine deficient
annotated property: IAO_0000115
annotated target: Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals.
has db xref: WB:WBPerson712

dopamine synthesis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042416
subclass of: dopamine metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042416
IAO_0000115: Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000235

Axiom
annotated source: dopamine synthesis defective
annotated property: IAO_0000115
annotated target: Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine.
has db xref: GO:0042416
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

dopamine catabolism defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042420
subclass of: dopamine metabolism variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042420
IAO_0000115: Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000236

Axiom
annotated source: dopamine catabolism defective
annotated property: IAO_0000115
annotated target: Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
has db xref: GO:0042420
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

foraging hyperactive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: foraging behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000237

Axiom
annotated source: foraging hyperactive
annotated property: IAO_0000115
annotated target: Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute.
has db xref: WB:WBPaper00031455
has db xref: WB:WBPaper00031570
has db xref: WB:WBPerson712

foraging reduced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: foraging behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000238

Axiom
annotated source: foraging reduced
annotated property: IAO_0000115
annotated target: Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals.
has db xref: WB:WBPaper00031455
has db xref: WB:WBPerson712

vulval cell lineage variant
type: Class
subclass of: P lineages variant
IAO_0000115: The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p.
has narrow synonym: vulval cell lineage abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: VPC lineage abnormal
id: WBPhenotype:0000239

Axiom
annotated source: vulval cell lineage variant
annotated property: IAO_0000115
annotated target: The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p.
has db xref: WB:WBPaper00005610
has db xref: WB:WBPerson2021

blast cell proliferation reduced
type: Class
subclass of: cell proliferation reduced
IAO_0000115: The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000240

Axiom
annotated source: blast cell proliferation reduced
annotated property: IAO_0000115
annotated target: The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control.
has db xref: WB:WBPerson2021

accumulated cell corpses
type: Class
subclass of: cell corpse number variant
IAO_0000115: Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000241

Axiom
annotated source: accumulated cell corpses
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed.
has db xref: WB:WBPerson712

body elongation defective
type: Class
subclass of: WBPhenotype_0001478
IAO_0000115: The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000242

Axiom
annotated source: body elongation defective
annotated property: IAO_0000115
annotated target: The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
has db xref: WB:WBPerson2021

engulfment failure by killer cell
type: Class
subclass of: WBPhenotype_0000885
IAO_0000115: Removal of cell corpses through a dedicated engulfment pathway is defective.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: corpse engulfment defective
has related synonym: persistent cell corpses
id: WBPhenotype:0000243

Axiom
annotated source: engulfment failure by killer cell
annotated property: IAO_0000115
annotated target: Removal of cell corpses through a dedicated engulfment pathway is defective.
has db xref: WB:WBPerson712

apoptotic arrest
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: apoptosis reduced
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006915
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: apoptosis block
id: WBPhenotype:0000244

Axiom
annotated source: apoptotic arrest
annotated property: IAO_0000115
annotated target: Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
has db xref: WB:WBPerson712

SM migration variant
type: Class
subclass of: WBPhenotype_0001230
IAO_0000115: Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad.
has narrow synonym: SM migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000245

Axiom
annotated source: SM migration variant
annotated property: IAO_0000115
annotated target: Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad.
has db xref: WB:WBPaper00003627
has db xref: WB:WBPerson2021

defecation cycle variable length
type: Class
subclass of: defecation cycle variant
IAO_0000115: Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000246

Axiom
annotated source: defecation cycle variable length
annotated property: IAO_0000115
annotated target: Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals.
has db xref: WB:WBPaper00031896
has db xref: WB:WBPerson712

sodium chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_26708
subclass of: WBPhenotype_0001440
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_26708
IAO_0000115: Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Na chemotaxis defective
has related synonym: sodium acetate chemotaxis defective
id: WBPhenotype:0000247

Axiom
annotated source: sodium chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant.
has db xref: WB:cab
has db xref: WB:cgc387

Axiom
annotated source: sodium chemotaxis defective
annotated property: hasRelatedSynonym
annotated target: sodium acetate chemotaxis defective
has db xref: WB:WBPerson2021

obsolete sensory neuroanatomy variant
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: sensory system variant
has narrow synonym: sensory neuroanatomy abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000248
deprecated: true

Axiom
annotated source: obsolete sensory neuroanatomy variant
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

osmotic avoidance defective
type: Class
subclass of: osmotic avoidance variant
IAO_0000115: Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000249

Axiom
annotated source: osmotic avoidance defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals.
has db xref: WB:WBPerson2021
has db xref: WB:cab

octopamine metabolism variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0046333
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: neurotransmitter metabolism variant
subclass of: WBPhenotype_0001518
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0046333
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control.
has narrow synonym: octopamine metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000250

Axiom
annotated source: octopamine metabolism variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control.
has db xref: GO:0046333
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

octopamine deficient
type: Class
subclass of: octopamine metabolism variant
IAO_0000115: Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000251

Axiom
annotated source: octopamine deficient
annotated property: IAO_0000115
annotated target: Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity.
has db xref: WB:WBPerson712

caffeine resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_27732
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_27732
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000252

Axiom
annotated source: caffeine resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

movement erratic
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000330
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007626
subclass of: WBPhenotype_0001701
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000330
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007626
IAO_0000115: Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: movement irregular
id: WBPhenotype:0000253

Axiom
annotated source: movement erratic
annotated property: IAO_0000115
annotated target: Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

chloride chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_17996
subclass of: WBPhenotype_0001439
subclass of: WBPhenotype_0001458
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_17996
IAO_0000115: Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Cl chemotaxis defective
id: WBPhenotype:0000254

Axiom
annotated source: chloride chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant.
has db xref: WB:cab
has db xref: WB:cgc387

amphid phasmid neuron morphology variant
type: Class
subclass of: WBPhenotype_0001527
IAO_0000115: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has narrow synonym: amphid phasmid morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000255
comment: WBbt:0005394, WBbt:0006753.

Axiom
annotated source: amphid phasmid neuron morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has db xref: WB:WBPaper00000938

amphid neuron morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005391
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: amphid phasmid neuron morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005391
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has narrow synonym: amphid morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000256
comment: WBbt:0005394.

Axiom
annotated source: amphid neuron morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has db xref: WB:WBPaper00000938

phasmid neuron morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005425
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: amphid phasmid neuron morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005425
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has narrow synonym: phasmid morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000257
comment: WBbt:0006753.

Axiom
annotated source: phasmid neuron morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
has db xref: WB:WBPaper00000938

cell secretion variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032940
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032940
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the regulated release of substances by a cell compared to control.
has alternative id: WBPhenotype:0000723
has exact synonym: cellular secretion abnormal
has narrow synonym: cell secretion abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000258
in subset: phenotype slim wb

Axiom
annotated source: cell secretion variant
annotated property: IAO_0000115
annotated target: Variations in the regulated release of substances by a cell compared to control.
has db xref: GO:0032940
has db xref: WB:WBPerson2021

sheath cell secretion variant
type: Class
subclass of: cell secretion variant
IAO_0000115: Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control.
has narrow synonym: sheath cell secretion abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000259

Axiom
annotated source: sheath cell secretion variant
annotated property: IAO_0000115
annotated target: Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control.
has db xref: WB:WBPaper00000822
has db xref: WB:WBPerson2021

sheath cell secretion failure
type: Class
subclass of: sheath cell secretion variant
IAO_0000115: The regulated release of materials by sheath cells is disrupted.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000260

Axiom
annotated source: sheath cell secretion failure
annotated property: IAO_0000115
annotated target: The regulated release of materials by sheath cells is disrupted.
has db xref: WB:WBPaper00028924
has db xref: WB:WBPerson2021

amphid sheath secretion failure
type: Class
subclass of: sheath cell secretion failure
IAO_0000115: Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000261

Axiom
annotated source: amphid sheath secretion failure
annotated property: IAO_0000115
annotated target: Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket.
has db xref: WB:WBPaper00028924
has db xref: WB:WBPerson2021

axoneme morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005930
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cilia morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005930
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
has narrow synonym: axoneme morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000262

Axiom
annotated source: axoneme morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
has db xref: WB:WBPaper00000932
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

axoneme short
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005930
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: axoneme morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005930
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000263

Axiom
annotated source: axoneme short
annotated property: IAO_0000115
annotated target: The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals.
has db xref: WB:WBPaper00000932
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

cAMP chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_17489
subclass of: WBPhenotype_0001441
subclass of: WBPhenotype_0001463
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_17489
IAO_0000115: Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000264

Axiom
annotated source: cAMP chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant.
has db xref: WB:WBPaper00001481
has db xref: WB:WBPaper00002033
has db xref: WB:cab
has db xref: WB:cgc387

odorant positive chemotaxis variant
type: Class
subclass of: positive chemotaxis variant
subclass of: WBPhenotype_0001048
IAO_0000115: Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons.
has narrow synonym: odorant positive chemotaxis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000265

Axiom
annotated source: odorant positive chemotaxis variant
annotated property: IAO_0000115
annotated target: Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons.
has db xref: WB:WBPerson2021
has db xref: WB:cab
has db xref: WB:cgc1786

cell cleavage variant
type: Class
subclass of: WBPhenotype_0000746
IAO_0000115: Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control.
has narrow synonym: cell cleavage abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000266

Axiom
annotated source: cell cleavage variant
annotated property: IAO_0000115
annotated target: Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell cleavage delayed
type: Class
subclass of: cell cleavage variant
subclass of: retarded heterochronic variations
IAO_0000115: Any variation that causes a delay in the stereotypical cleavage event compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000267

Axiom
annotated source: cell cleavage delayed
annotated property: IAO_0000115
annotated target: Any variation that causes a delay in the stereotypical cleavage event compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

P cell cleavage delayed
type: Class
subclass of: cell cleavage delayed
IAO_0000115: Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000268

Axiom
annotated source: P cell cleavage delayed
annotated property: IAO_0000115
annotated target: Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete unclassified
type: Class
IAO_0000115: OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000269
deprecated: true

Axiom
annotated source: obsolete unclassified
annotated property: IAO_0000115
annotated target: OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pleiotropic defects severe early emb
type: Class
subclass of: WBPhenotype_0001007
IAO_0000115: Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000270

Axiom
annotated source: pleiotropic defects severe early emb
annotated property: IAO_0000115
annotated target: Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity.
has db xref: WB:cab
has db xref: WB:cgc7141

obsolete cell cycle slow
type: Class
IAO_0000115: OBSOLETE.
consider: cell cycle delayed
consider: WBPhenotype_0001995
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000271
deprecated: true

egg laying irregular
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000044
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: egg laying variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000044
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000272

Axiom
annotated source: egg laying irregular
annotated property: IAO_0000115
annotated target: The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

thrashing reduced
type: Class
subclass of: WBPhenotype_0001700
IAO_0000115: The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000273

Axiom
annotated source: thrashing reduced
annotated property: IAO_0000115
annotated target: The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms.
has db xref: WB:cab
has db xref: WB:cgc7388

dead eggs laid
type: Class
subclass of: egg laying variant
subclass of: WBPhenotype_0000806
IAO_0000115: Animals lay eggs that are inviable.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000274

Axiom
annotated source: dead eggs laid
annotated property: IAO_0000115
annotated target: Animals lay eggs that are inviable.
has db xref: WB:cab

organism UV hypersensitive
type: Class
subclass of: organism UV response variant
IAO_0000115: Organisms respond to UV at a lower dose or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000275

Axiom
annotated source: organism UV hypersensitive
annotated property: IAO_0000115
annotated target: Organisms respond to UV at a lower dose or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

organism X ray response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010165
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism ionizing radiation response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010165
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals.
has narrow synonym: organism X ray response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000276

Axiom
annotated source: organism X ray response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals.
has db xref: WB:WBPerson557

rhythm slow
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048511
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048511
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The timing of a biological cycle that recurs with regularity is delayed compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000277
in subset: phenotype slim wb

Axiom
annotated source: rhythm slow
annotated property: IAO_0000115
annotated target: The timing of a biological cycle that recurs with regularity is delayed compared to control.
has db xref: GO:0048511
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body region pigmentation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005738
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: pigmentation phenotype
subclass of: body region morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005738
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region.
has exact synonym: body region pigmentation abnormal
has exact synonym: body region pigmentation variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000278

Axiom
annotated source: body region pigmentation phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region.
has db xref: WB:WBPerson557

spicule insertion defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034609
subclass of: WBPhenotype_0001414
subclass of: WBPhenotype_0004006
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034609
IAO_0000115: Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000279

Axiom
annotated source: spicule insertion defective
annotated property: IAO_0000115
annotated target: Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
has db xref: GO:0034609
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

breaks in alae
type: Class
subclass of: WBPhenotype_0001412
IAO_0000115: The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas).
has exact synonym: gapped alae
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000280

Axiom
annotated source: breaks in alae
annotated property: IAO_0000115
annotated target: The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male sex muscle development variant
type: Class
subclass of: sex muscle development variant
IAO_0000115: Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control.
has narrow synonym: male sex muscle development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000281

Axiom
annotated source: male sex muscle development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hermaphrodite sex muscle development variant
type: Class
subclass of: sex muscle development variant
IAO_0000115: Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control.
has narrow synonym: hermaphrodite sex muscle development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000282

Axiom
annotated source: hermaphrodite sex muscle development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

vulva uterus connection defective
type: Class
subclass of: reproductive system development variant
IAO_0000115: Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals.
has narrow synonym: AC block
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000283

Axiom
annotated source: vulva uterus connection defective
annotated property: IAO_0000115
annotated target: Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals.
has db xref: WB:WBPaper00003386
has db xref: WB:WBPaper00006298
has db xref: WB:WBPaper00027236
has db xref: WB:WBPaper00027316
has db xref: WB:WBPerson712

sperm transfer defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007320
subclass of: WBPhenotype_0001414
subclass of: WBPhenotype_0004006
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007320
IAO_0000115: Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000284

Axiom
annotated source: sperm transfer defective
annotated property: IAO_0000115
annotated target: Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract.
has db xref: GO:0007320
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

ray tips swollen
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
subclass of: male ray morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
IAO_0000115: The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000285

Axiom
annotated source: ray tips swollen
annotated property: IAO_0000115
annotated target: The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

embryo disorganized
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
subclass of: WBPhenotype_0000749
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
IAO_0000115: Embryos fail to be organized in the same manner as observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000286

Axiom
annotated source: embryo disorganized
annotated property: IAO_0000115
annotated target: Embryos fail to be organized in the same manner as observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete vulval invagination L4 abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: vulval invagination variant L4
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000287
deprecated: true

distal germline variant
type: Class
subclass of: WBPhenotype_0000812
IAO_0000115: Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals.
has narrow synonym: distal germline abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: distal germ line abnormal
id: WBPhenotype:0000288

Axiom
annotated source: distal germline variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

uterus morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006760
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001335
subclass of: WBPhenotype_0002556
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006760
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas).
has narrow synonym: uterus morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000289

Axiom
annotated source: uterus morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

sperm absent
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: no differentiated gametes
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack fully specialized male gametes that are competent for fertilization.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: no sperm
id: WBPhenotype:0000290

Axiom
annotated source: sperm absent
annotated property: IAO_0000115
annotated target: Animals lack fully specialized male gametes that are competent for fertilization.
has db xref: WB:WBPerson2021

no oocytes
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006797
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: no differentiated gametes
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006797
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: oocytes absent
id: WBPhenotype:0000291

Axiom
annotated source: no oocytes
annotated property: IAO_0000115
annotated target: Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
has db xref: WB:WBPerson2021

organ system pigmentation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005746
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: pigmentation phenotype
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005746
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system.
has exact synonym: organ system pigmentation abnormal
has exact synonym: organ system pigmentation variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000292

Axiom
annotated source: organ system pigmentation phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system.
has db xref: WB:WBPerson557

alimentary system pigmentation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system pigmentation phenotype
subclass of: alimentary system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system.
has narrow synonym: alimentary system pigmentation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000293

Axiom
annotated source: alimentary system pigmentation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system.
has db xref: WB:WBPerson557

intestine dark
type: Class
subclass of: alimentary system pigmentation variant
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine.
has broad synonym: Din
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000294

Axiom
annotated source: intestine dark
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine.
has db xref: WB:WBPerson557

thermotolerance increased
type: Class
subclass of: organism temperature response variant
IAO_0000115: Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
has narrow synonym: intrinsic thermotolerance increased
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000295

Axiom
annotated source: thermotolerance increased
annotated property: IAO_0000115
annotated target: Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
has db xref: WB:WBPaper00005836
has db xref: WB:WBPerson712

spicules crumpled
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001810
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005312
subclass of: spicule morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001810
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005312
IAO_0000115: The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000296

Axiom
annotated source: spicules crumpled
annotated property: IAO_0000115
annotated target: The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

rays fused
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000642
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
subclass of: cell fusion variant
subclass of: male tail sensory ray development variant
subclass of: male ray morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000642
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
IAO_0000115: Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another.
has alternative id: WBPhenotype:0001241
has exact synonym: ray fusion
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000297

Axiom
annotated source: rays fused
annotated property: IAO_0000115
annotated target: Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

rays displaced
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001852
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
subclass of: male ray morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001852
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
IAO_0000115: Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000298

Axiom
annotated source: rays displaced
annotated property: IAO_0000115
annotated target: Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

sensillum morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: nervous system morphology variant
subclass of: WBPhenotype_0002553
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
has narrow synonym: sensillum morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: chemosensory cell morphology abnormal
id: WBPhenotype:0000299

Axiom
annotated source: sensillum morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
has db xref: WB:WBPaper00000214
has db xref: WB:WBPaper00000938
has db xref: WB:WBPerson712

amphid sheath cell morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006754
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000972
subclass of: WBPhenotype_0001527
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006754
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures.
has narrow synonym: amphid sheath cell morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000300

Axiom
annotated source: amphid sheath cell morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures.
has db xref: WB:WBPaper00000214
has db xref: WB:WBPaper00000503
has db xref: WB:WBPaper00000822
has db xref: WB:WBPerson712

distal tip cell reflex failure
type: Class
subclass of: distal tip cell migration variant
IAO_0000115: A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000301

Axiom
annotated source: distal tip cell reflex failure
annotated property: IAO_0000115
annotated target: A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm.
has db xref: WB:WBPaper00029151
has db xref: WB:WBPerson2021

benzaldehyde chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_22698
subclass of: WBPhenotype_0001060
subclass of: WBPhenotype_0001468
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_22698
IAO_0000115: Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000302

Axiom
annotated source: benzaldehyde chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive.
has db xref: WB:WBPaper00001786

diacetyl chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_16583
subclass of: WBPhenotype_0001438
subclass of: WBPhenotype_0001470
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_16583
IAO_0000115: Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000303

Axiom
annotated source: diacetyl chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive.
has db xref: WB:WBPaper00001786

isoamyl alcohol chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_15837
subclass of: WBPhenotype_0001438
subclass of: WBPhenotype_0001472
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_15837
IAO_0000115: Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000304

Axiom
annotated source: isoamyl alcohol chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive.
has db xref: WB:cab
has db xref: WB:cgc1786

pheromone sensation variant
type: Class
subclass of: WBPhenotype_0000738
IAO_0000115: Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals.
has narrow synonym: pheromone sensation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000305

Axiom
annotated source: pheromone sensation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals.
has db xref: GO:0043695
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

transgene expression variant
type: Class
subclass of: WBPhenotype_0000717
IAO_0000115: Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals.
has narrow synonym: transgene expression abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000306
in subset: phenotype slim wb

Axiom
annotated source: transgene expression variant
annotated property: IAO_0000115
annotated target: Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals.
has db xref: WB:WBPerson557

dauer pheromone sensation defective
type: Class
subclass of: WBPhenotype_0001479
IAO_0000115: Animals fail to detect a pheromone stimulus that induces dauer formation in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000307

Axiom
annotated source: dauer pheromone sensation defective
annotated property: IAO_0000115
annotated target: Animals fail to detect a pheromone stimulus that induces dauer formation in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dauer development phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040024
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000750
subclass of: WBPhenotype_0002527
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040024
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage.
has alternative id: WBPhenotype:0000159
has exact synonym: dauer development abnormal
has exact synonym: dauer development variant
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: dauer arrest abnormal
has related synonym: dauer arrest variant
has related synonym: diapause variant
id: WBPhenotype:0000308

Axiom
annotated source: dauer development phenotype
annotated property: IAO_0000115
annotated target: Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage.
has db xref: WB:kmva

SDS sensitive dauer
type: Class
subclass of: WBPhenotype_0001546
subclass of: WBPhenotype_0001918
IAO_0000115: Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000309

Axiom
annotated source: SDS sensitive dauer
annotated property: IAO_0000115
annotated target: Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control.
has db xref: WB:WBPerson2021

cilia absent
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cilia morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000310

Axiom
annotated source: cilia absent
annotated property: IAO_0000115
annotated target: Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals.
has db xref: WB:WBPaper00000932
has db xref: WB:WBPerson712

obsolete semi sterile
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: sterile
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000311
deprecated: true

dauer pheromone production defective
type: Class
subclass of: organism crowding response variant
subclass of: WBPhenotype_0001547
IAO_0000115: Animals are incapable of synthesizing pheromones that induce dauer formation in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000312

Axiom
annotated source: dauer pheromone production defective
annotated property: IAO_0000115
annotated target: Animals are incapable of synthesizing pheromones that induce dauer formation in control animals.
has db xref: GO:0042446
has db xref: WB:WBPerson2021

meiotic progression during oogenesis variant
type: Class
subclass of: oogenesis variant
IAO_0000115: Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
has narrow synonym: meiotic progression during oogenesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000313

Axiom
annotated source: meiotic progression during oogenesis variant
annotated property: IAO_0000115
annotated target: Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
has db xref: WB:WBPaper00026997
has db xref: WB:WBPerson2021

scrawny
type: Class
subclass of: body size variant
IAO_0000115: Animals are slight or meager in body size compared to control animals at the same developmental stage.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000314

Axiom
annotated source: scrawny
annotated property: IAO_0000115
annotated target: Animals are slight or meager in body size compared to control animals at the same developmental stage.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

mechanosensation variant
type: Class
subclass of: organism behavior variant
subclass of: WBPhenotype_0000738
IAO_0000115: Any variation with respect to perception or response to mechanical stimuli compared to control animals.
has alternative id: WBPhenotype:0000513
has broad synonym: Mec
has exact synonym: touch response abnormal
has narrow synonym: mechanosensation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000315
in subset: phenotype slim wb

Axiom
annotated source: mechanosensation variant
annotated property: IAO_0000115
annotated target: Any variation with respect to perception or response to mechanical stimuli compared to control animals.
has db xref: WB:cab

touch resistant tail
type: Class
subclass of: touch resistant
IAO_0000115: Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail.
has broad synonym: touch resistant posterior body
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: touch insensitive tail
id: WBPhenotype:0000316

Axiom
annotated source: touch resistant tail
annotated property: IAO_0000115
annotated target: Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail.
has db xref: WB:WBPaper00000502
has db xref: WB:WBPaper00001133
has db xref: WB:WBPaper00001705
has db xref: WB:WBPerson557

head withdrawal defective
type: Class
subclass of: mechanosensation variant
IAO_0000115: Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000317

Axiom
annotated source: head withdrawal defective
annotated property: IAO_0000115
annotated target: Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell cycle delayed
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007049
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: retarded heterochronic variations
subclass of: WBPhenotype_0001995
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007049
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000318

Axiom
annotated source: cell cycle delayed
annotated property: IAO_0000115
annotated target: Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells.
has db xref: WB:WBPerson712

large
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000586
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body size variant
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000586
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals have increased girth and increased length compared to control animals at the same developmental stage.
has exact synonym: body size enlarged
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000319

Axiom
annotated source: large
annotated property: IAO_0000115
annotated target: Animals have increased girth and increased length compared to control animals at the same developmental stage.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

reduced viability after freezing
type: Class
subclass of: stress induced lethality increased
IAO_0000115: Animals show a decrease in survivorship after thawing compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000320

Axiom
annotated source: reduced viability after freezing
annotated property: IAO_0000115
annotated target: Animals show a decrease in survivorship after thawing compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nose morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0008426
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: head morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0008426
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
has narrow synonym: nose morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000321

Axiom
annotated source: nose morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nose rounded
type: Class
subclass of: nose morphology variant
IAO_0000115: The extreme anterior part of the body appears blunted in shape.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000322

Axiom
annotated source: nose rounded
annotated property: IAO_0000115
annotated target: The extreme anterior part of the body appears blunted in shape.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

head swollen
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
subclass of: head morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
IAO_0000115: The most anterior portion of the animal appears bloated or distended.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000323

Axiom
annotated source: head swollen
annotated property: IAO_0000115
annotated target: The most anterior portion of the animal appears bloated or distended.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

short
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: small
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit a decreased body length compared to control animals of the same developmental stage.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000324

Axiom
annotated source: short
annotated property: IAO_0000115
annotated target: Animals exhibit a decreased body length compared to control animals of the same developmental stage.
has db xref: WB:WBPerson712

arecoline hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2814
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001579
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2814
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000325

Axiom
annotated source: arecoline hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

arecoline resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2814
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001502
subclass of: WBPhenotype_0001578
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 2814
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000326

Axiom
annotated source: arecoline resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

corpus contraction defect
type: Class
subclass of: WBPhenotype_0000747
IAO_0000115: Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000327

Axiom
annotated source: corpus contraction defect
annotated property: IAO_0000115
annotated target: Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

terminal bulb contraction variant
type: Class
subclass of: WBPhenotype_0000980
IAO_0000115: Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine.
has narrow synonym: terminal bulb contraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000328

Axiom
annotated source: terminal bulb contraction variant
annotated property: IAO_0000115
annotated target: Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine.
has db xref: WB:WBPaper00001696

pumping asynchronous
type: Class
subclass of: WBPhenotype_0001006
IAO_0000115: The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000329

Axiom
annotated source: pumping asynchronous
annotated property: IAO_0000115
annotated target: The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously.
has db xref: WB:WBPaper00001696

pharyngeal relaxation defective
type: Class
subclass of: WBPhenotype_0001004
IAO_0000115: Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000330

Axiom
annotated source: pharyngeal relaxation defective
annotated property: IAO_0000115
annotated target: Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid.
has db xref: WB:WBPaper00001709

inhibitors of na k atpase resistant
type: Class
subclass of: drug resistant
IAO_0000115: Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has narrow synonym: ouabain resistant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000331

Axiom
annotated source: inhibitors of na k atpase resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson2021

inhibitors of sodium potassium ATPase hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_63510
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_63510
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000332

Axiom
annotated source: inhibitors of sodium potassium ATPase hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

pharyngeal pumps brief
type: Class
subclass of: WBPhenotype_0001006
IAO_0000115: The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000333

Axiom
annotated source: pharyngeal pumps brief
annotated property: IAO_0000115
annotated target: The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

isthmus corpus slippery
type: Class
subclass of: pharynx slippery
IAO_0000115: Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000334

Axiom
annotated source: isthmus corpus slippery
annotated property: IAO_0000115
annotated target: Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx.
has db xref: WB:WBPaper00001696

pharynx slippery
type: Class
subclass of: pharyngeal pumping variant
IAO_0000115: Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000335

Axiom
annotated source: pharynx slippery
annotated property: IAO_0000115
annotated target: Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen.
has db xref: WB:WBPaper00001696

terminal bulb relaxation variant
type: Class
subclass of: pharyngeal relaxation defective
IAO_0000115: Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position.
has narrow synonym: terminal bulb relaxation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000336

Axiom
annotated source: terminal bulb relaxation variant
annotated property: IAO_0000115
annotated target: Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position.
has db xref: WB:WBPaper00001696

grinder relaxation defective
type: Class
subclass of: WBPhenotype_0001480
IAO_0000115: Failure of the grinder to come to a full relaxed position between pumps compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000337

Axiom
annotated source: grinder relaxation defective
annotated property: IAO_0000115
annotated target: Failure of the grinder to come to a full relaxed position between pumps compared to control.
has db xref: WB:WBPaper00001709

tail swelling
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
subclass of: tail morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001851
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
IAO_0000115: Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum.
has broad synonym: Dar
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: deformed anal region
id: WBPhenotype:0000338

Axiom
annotated source: tail swelling
annotated property: IAO_0000115
annotated target: Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum.
has db xref: WB:WBPaper00026735
has db xref: WB:cab

transient bloating
type: Class
subclass of: WBPhenotype_0000862
IAO_0000115: Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000339

Axiom
annotated source: transient bloating
annotated property: IAO_0000115
annotated target: Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

imipramine resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_47499
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: WBPhenotype_0001598
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_47499
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000340

Axiom
annotated source: imipramine resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

imipramine hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_47499
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_47499
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000341

Axiom
annotated source: imipramine hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

bursa morphology variant
type: Class
subclass of: male tail morphology variant
IAO_0000115: Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control.
has narrow synonym: bursa morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000342

Axiom
annotated source: bursa morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete cloaca morphology abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: WBPhenotype_0000908
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000343
deprecated: true

cloacal structures protrude
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005774
subclass of: WBPhenotype_0000908
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005774
IAO_0000115: Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000344

Axiom
annotated source: cloacal structures protrude
annotated property: IAO_0000115
annotated target: Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

VPC cell division variant
type: Class
subclass of: WBPhenotype_0000746
IAO_0000115: Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control.
has narrow synonym: VPC cell division abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000345

Axiom
annotated source: VPC cell division variant
annotated property: IAO_0000115
annotated target: Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

adult pigmentation variant
type: Class
subclass of: WBPhenotype_0001009
IAO_0000115: Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
has narrow synonym: adult pigmentation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000346

Axiom
annotated source: adult pigmentation variant
annotated property: IAO_0000115
annotated target: Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
has db xref: WB:WBPerson557

rectal development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system.
has narrow synonym: rectal development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000347

Axiom
annotated source: rectal development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete muscle activation defective
type: Class
IAO_0000115: OBSOLETE.
consider: WBPhenotype_0001735
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000348
deprecated: true

flaccid
type: Class
subclass of: body posture variant
IAO_0000115: A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: floppy
has related synonym: limp
id: WBPhenotype:0000349

Axiom
annotated source: flaccid
annotated property: IAO_0000115
annotated target: A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hermaphrodite tail spike variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001340
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006979
subclass of: WBPhenotype_0000968
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001340
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006979
IAO_0000115: Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000350

Axiom
annotated source: hermaphrodite tail spike variant
annotated property: IAO_0000115
annotated target: Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

failure to hatch
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: hatching variant
subclass of: embryonic lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to emerge from an egg shell.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000351

Axiom
annotated source: failure to hatch
annotated property: IAO_0000115
annotated target: Animals fail to emerge from an egg shell.
has db xref: GO:0035188
has db xref: WB:WBPerson2021

backing uncoordinated
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000770
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043057
subclass of: WBPhenotype_0001005
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000770
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043057
IAO_0000115: Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000352

Axiom
annotated source: backing uncoordinated
annotated property: IAO_0000115
annotated target: Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion.
has db xref: WB:WBPaper00001709

backing increased
type: Class
subclass of: WBPhenotype_0001005
IAO_0000115: Animals spend more time backing compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000353

Axiom
annotated source: backing increased
annotated property: IAO_0000115
annotated target: Animals spend more time backing compared to control animals.
has db xref: WB:cab

cell differentiation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030154
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030154
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
has narrow synonym: cell differentiation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000354
in subset: phenotype slim wb

Axiom
annotated source: cell differentiation variant
annotated property: IAO_0000115
annotated target: Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
has db xref: WB:WBPerson2021

HSN differentiation precocious
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000694
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030154
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0006830
subclass of: cell differentiation variant
subclass of: precocious heterochronic variations
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000694
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030154
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0006830
IAO_0000115: Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000355

Axiom
annotated source: HSN differentiation precocious
annotated property: IAO_0000115
annotated target: Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control.
has db xref: WB:WBPerson2021

spermatogenesis delayed
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: spermatogenesis variant
subclass of: WBPhenotype_0000848
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The progression of immature germ cells to functional sperm is retarded compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000356

Axiom
annotated source: spermatogenesis delayed
annotated property: IAO_0000115
annotated target: The progression of immature germ cells to functional sperm is retarded compared to control.
has db xref: WB:WBPaper00005566
has db xref: WB:WBPerson2021

unfertilized oocytes laid
type: Class
subclass of: egg laying variant
IAO_0000115: Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000357

Axiom
annotated source: unfertilized oocytes laid
annotated property: IAO_0000115
annotated target: Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm.
has db xref: WB:WBPaper00001075
has db xref: WB:WBPerson2021

extra cell division postembryonic
type: Class
subclass of: WBPhenotype_0000825
IAO_0000115: Animals execute supernumerary cell divisions post-hatching.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: supernumerary cell divisions
id: WBPhenotype:0000358

Axiom
annotated source: extra cell division postembryonic
annotated property: IAO_0000115
annotated target: Animals execute supernumerary cell divisions post-hatching.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

tunicamycin response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1904576
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1904576
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.
has narrow synonym: tunicamycin response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000359

Axiom
annotated source: tunicamycin response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.
has db xref: WB:WBPaper00030877
has db xref: WB:WBperson557

cytoplasmic streaming defective
type: Class
subclass of: WBPhenotype_0002612
IAO_0000115: The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000360
comment: Possible XP.

Axiom
annotated source: cytoplasmic streaming defective
annotated property: IAO_0000115
annotated target: The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired.
has db xref: GO:0099636
has db xref: WB:WBPaper00050908
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

lima bean arrest
type: Class
subclass of: WBPhenotype_0000867
IAO_0000115: Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas).
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: arrest during epiboly
id: WBPhenotype:0000361

Axiom
annotated source: lima bean arrest
annotated property: IAO_0000115
annotated target: Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

blastocoel variant
type: Class
subclass of: gastrulation variant
IAO_0000115: Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas).
has narrow synonym: blastocoel abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000362

Axiom
annotated source: blastocoel variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell division slow
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: retarded heterochronic variations
subclass of: WBPhenotype_0000746
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000363

Axiom
annotated source: cell division slow
annotated property: IAO_0000115
annotated target: Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

gut granule birefringence misplaced
type: Class
subclass of: WBPhenotype_0002240
IAO_0000115: The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000364

Axiom
annotated source: gut granule birefringence misplaced
annotated property: IAO_0000115
annotated target: The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen.
has db xref: WB:WBPaper00025094

embryo osmotic integrity defective early emb
type: Class
subclass of: WBPhenotype_0001178
IAO_0000115: Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing.
has broad synonym: Emb
has broad synonym: Eos
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000365

Axiom
annotated source: embryo osmotic integrity defective early emb
annotated property: IAO_0000115
annotated target: Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing.
has db xref: WB:cab
has db xref: WB:cgc7141

three fold arrest
type: Class
subclass of: WBPhenotype_0000779
IAO_0000115: Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: active elongation arrest
id: WBPhenotype:0000366

Axiom
annotated source: three fold arrest
annotated property: IAO_0000115
annotated target: Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo.
has db xref: WB:WBPerson101

comma arrest emb
type: Class
subclass of: WBPhenotype_0000864
IAO_0000115: Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas).
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: end of epiboly arrest
id: WBPhenotype:0000367

Axiom
annotated source: comma arrest emb
annotated property: IAO_0000115
annotated target: Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

one point five fold arrest emb
type: Class
subclass of: WBPhenotype_0000864
IAO_0000115: Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: arrest beginning elongation
id: WBPhenotype:0000368

Axiom
annotated source: one point five fold arrest emb
annotated property: IAO_0000115
annotated target: Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo.
has db xref: WB:WBPerson101

pretzel arrest
type: Class
subclass of: WBPhenotype_0000779
IAO_0000115: Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas).
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: end of elongation arrest
id: WBPhenotype:0000369

Axiom
annotated source: pretzel arrest
annotated property: IAO_0000115
annotated target: Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

egg long
type: Class
subclass of: egg shape variable
IAO_0000115: The fertilized oocytes have a greater than standard length measured end to end compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000370

Axiom
annotated source: egg long
annotated property: IAO_0000115
annotated target: The fertilized oocytes have a greater than standard length measured end to end compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell division incomplete
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
subclass of: WBPhenotype_0000746
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000297
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
IAO_0000115: The physical partitioning and separation of a cell into daughter cells is interupted.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000371

Axiom
annotated source: cell division incomplete
annotated property: IAO_0000115
annotated target: The physical partitioning and separation of a cell into daughter cells is interupted.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no polar body formation
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0008429
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000775
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0008429
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000372

Axiom
annotated source: no polar body formation
annotated property: IAO_0000115
annotated target: Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

egg shape variable
type: Class
subclass of: egg morphology variant
IAO_0000115: The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000373

Axiom
annotated source: egg shape variable
annotated property: IAO_0000115
annotated target: The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

early divisions prolonged
type: Class
subclass of: WBPhenotype_0000749
IAO_0000115: The time interval in which early embryonic cell divisions occur is increased compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000374

Axiom
annotated source: early divisions prolonged
annotated property: IAO_0000115
annotated target: The time interval in which early embryonic cell divisions occur is increased compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

later divisions prolonged
type: Class
subclass of: WBPhenotype_0000749
IAO_0000115: The time interval in which late embryonic cell divisions occur is increased compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000375

Axiom
annotated source: later divisions prolonged
annotated property: IAO_0000115
annotated target: The time interval in which late embryonic cell divisions occur is increased compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no uterine cavity
type: Class
subclass of: uterus morphology variant
IAO_0000115: Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000376

Axiom
annotated source: no uterine cavity
annotated property: IAO_0000115
annotated target: Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

canal lumen morphology variant
type: Class
subclass of: excretory canal morphology variant
IAO_0000115: Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals.
has narrow synonym: canal lumen morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000377

Axiom
annotated source: canal lumen morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pharyngeal pumping shallow
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001472
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
subclass of: pharyngeal pumping variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001472
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
IAO_0000115: Pharyngeal muscle contractions show less displacement than that observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000378

Axiom
annotated source: pharyngeal pumping shallow
annotated property: IAO_0000115
annotated target: Pharyngeal muscle contractions show less displacement than that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

head notched
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001495
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
subclass of: head morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001495
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
IAO_0000115: The most anterior portion of the animal contains a V-shaped indentation.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000379

Axiom
annotated source: head notched
annotated property: IAO_0000115
annotated target: The most anterior portion of the animal contains a V-shaped indentation.
has db xref: WB:WBPaper00000031

expulsion infrequent
type: Class
subclass of: WBPhenotype_0000996
IAO_0000115: The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000380

Axiom
annotated source: expulsion infrequent
annotated property: IAO_0000115
annotated target: The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus.
has db xref: WB:WBPaper00002315
has db xref: WB:WBPerson712

serotonin reuptake inhibitor resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_50949
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_50949
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000381

Axiom
annotated source: serotonin reuptake inhibitor resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

serotonin reuptake inhibitor hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_50949
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_50949
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000382

Axiom
annotated source: serotonin reuptake inhibitor hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

lipid synthesis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008610
subclass of: WBPhenotype_0000725
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008610
IAO_0000115: The de novo synthesis of any lipid species is reduced compared to that observed in control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: lipid synthesis decreased
id: WBPhenotype:0000383

Axiom
annotated source: lipid synthesis defective
annotated property: IAO_0000115
annotated target: The de novo synthesis of any lipid species is reduced compared to that observed in control animals.
has db xref: WB:WBPerson712

axon guidance variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007411
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000944
subclass of: WBPhenotype_0001224
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007411
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues).
has narrow synonym: axon guidance abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: axon pathfinding abnormal
id: WBPhenotype:0000384

Axiom
annotated source: axon guidance variant
annotated property: IAO_0000115
annotated target: Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues).
has db xref: GO:0048846
has db xref: WB:WBPerson2021

sperm excess
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: spermatogenesis variant
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals produce an increased sperm population compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000385

Axiom
annotated source: sperm excess
annotated property: IAO_0000115
annotated target: Animals produce an increased sperm population compared to control.
has db xref: WB:WBPerson2021

genotoxic chemical induced apoptosis variant
type: Class
subclass of: WBPhenotype_0002152
IAO_0000115: Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals.
has narrow synonym: genotoxic induced apoptosis abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: DNA damage induced apoptosis abnormal
id: WBPhenotype:0000386

Axiom
annotated source: genotoxic chemical induced apoptosis variant
annotated property: IAO_0000115
annotated target: Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals.
has db xref: WB:WBPaper00032006
has db xref: WB:WBPaper00032243
has db xref: WB:WBPaper00032356
has db xref: WB:WBPerson712

sperm nonmotile
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000300
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
subclass of: WBPhenotype_0000987
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000300
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
IAO_0000115: The mature male gametes lack self-propelled movement.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000387

Axiom
annotated source: sperm nonmotile
annotated property: IAO_0000115
annotated target: The mature male gametes lack self-propelled movement.
has db xref: GO:0030317
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

sperm morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000900
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006798
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas).
has narrow synonym: sperm morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000388

Axiom
annotated source: sperm morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hermaphrodite sperm fertilization defective
type: Class
subclass of: hermaphrodite sterile
subclass of: WBPhenotype_0002440
IAO_0000115: Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte.
has broad synonym: Fer
has broad synonym: Spe
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000389

Axiom
annotated source: hermaphrodite sperm fertilization defective
annotated property: IAO_0000115
annotated target: Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte.
has db xref: WB:WBPaper00001075
has db xref: WB:WBPerson2021

spermatid activation defective
type: Class
subclass of: spermatogenesis variant
IAO_0000115: Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: spermiogenesis defective
id: WBPhenotype:0000390

Axiom
annotated source: spermatid activation defective
annotated property: IAO_0000115
annotated target: Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases.
has db xref: WB:WBPaper00000884
has db xref: WB:WBPaper00027300
has db xref: WB:WBPerson2021

defecation missing motor steps
type: Class
subclass of: defecation variant
IAO_0000115: Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000391

Axiom
annotated source: defecation missing motor steps
annotated property: IAO_0000115
annotated target: Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

intestinal fluorescence increased
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001926
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
subclass of: alimentary system pigmentation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001926
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005772
IAO_0000115: Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000392

Axiom
annotated source: intestinal fluorescence increased
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
has db xref: WB:WBPerson557

cell migration failure
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016477
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell migration variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016477
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Characteristic movement of cells from one site to another is abolished compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000393

Axiom
annotated source: cell migration failure
annotated property: IAO_0000115
annotated target: Characteristic movement of cells from one site to another is abolished compared to control.
has db xref: WB:WBPerson2021

electrophoretic variant protein
type: Class
subclass of: protein expression variant
IAO_0000115: Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000394

Axiom
annotated source: electrophoretic variant protein
annotated property: IAO_0000115
annotated target: Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no differentiated gametes
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000300
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000894
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000300
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals are agametic (lack mature germ cells).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000395

Axiom
annotated source: no differentiated gametes
annotated property: IAO_0000115
annotated target: Animals are agametic (lack mature germ cells).
has db xref: WB:WBPerson2021

non reflexed gonad arms
type: Class
subclass of: somatic gonad development variant
IAO_0000115: Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000396

Axiom
annotated source: non reflexed gonad arms
annotated property: IAO_0000115
annotated target: Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern.
has db xref: WB:WBPaper00005086
has db xref: WB:WBPaper00029151
has db xref: WB:WBPerson2021

harsh body touch resistant
type: Class
subclass of: touch resistant
IAO_0000115: Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: harsh body touch insensitive
id: WBPhenotype:0000397

Axiom
annotated source: harsh body touch resistant
annotated property: IAO_0000115
annotated target: Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls.
has db xref: WB:WBPaper00000502

light body touch resistant
type: Class
subclass of: touch resistant
IAO_0000115: Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: light body touch insensitive
id: WBPhenotype:0000398

Axiom
annotated source: light body touch resistant
annotated property: IAO_0000115
annotated target: Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls.
has db xref: WB:WBPaper00000502

somatic gonad development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: gonad development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas).
has narrow synonym: somatic gonad development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000399

Axiom
annotated source: somatic gonad development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

somatic gonad primordium development defective
type: Class
subclass of: somatic gonad development variant
IAO_0000115: The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000400

Axiom
annotated source: somatic gonad primordium development defective
annotated property: IAO_0000115
annotated target: The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no uterus
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006760
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: reproductive system development variant
subclass of: WBPhenotype_0002556
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006760
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000401

Axiom
annotated source: no uterus
annotated property: IAO_0000115
annotated target: Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

avoids bacterial lawn
type: Class
subclass of: feeding behavior variant
subclass of: WBPhenotype_0002545
IAO_0000115: Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000402

Axiom
annotated source: avoids bacterial lawn
annotated property: IAO_0000115
annotated target: Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal.
has db xref: WB:WBPaper00029071
has db xref: WB:WBPerson2021

sperm transfer initiation defective
type: Class
subclass of: sperm transfer defective
IAO_0000115: Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000403

Axiom
annotated source: sperm transfer initiation defective
annotated property: IAO_0000115
annotated target: Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control.
has db xref: WB:WBPaper00028400

delayed hatching
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: hatching variant
subclass of: retarded heterochronic variations
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035188
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The emergence of larvae from their protective egg shells is retarded compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000404

Axiom
annotated source: delayed hatching
annotated property: IAO_0000115
annotated target: The emergence of larvae from their protective egg shells is retarded compared to control animals.
has db xref: GO:0035188
has db xref: WB:WBPerson2021

giant oocytes
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000586
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006797
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001260
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000586
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006797
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The size of haploid female germ cells (oocytes) are significantly larger compared to control.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: oocytes large
id: WBPhenotype:0000405

Axiom
annotated source: giant oocytes
annotated property: IAO_0000115
annotated target: The size of haploid female germ cells (oocytes) are significantly larger compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

lumpy
type: Class
subclass of: organism morphology variant
IAO_0000115: Animals have protrusions or bumps on their exterior which are not characteristic of control animals.
has broad synonym: Lpy
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000406

Axiom
annotated source: lumpy
annotated property: IAO_0000115
annotated target: Animals have protrusions or bumps on their exterior which are not characteristic of control animals.
has db xref: WB:WBPerson557

obsolete ray loss
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: WBPhenotype_0001509
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000407
deprecated: true

dauer recovery inhibited
type: Class
subclass of: dauer recovery variant
IAO_0000115: The process through which a dauer larva reverts to normal developmental programs is blocked.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000408

Axiom
annotated source: dauer recovery inhibited
annotated property: IAO_0000115
annotated target: The process through which a dauer larva reverts to normal developmental programs is blocked.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism morphology variable
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001227
subclass of: organism morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001227
IAO_0000115: Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals.
has broad synonym: Vab
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000409

Axiom
annotated source: organism morphology variable
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no defecation cycle
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035882
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: defecation cycle variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0035882
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000410

Axiom
annotated source: no defecation cycle
annotated property: IAO_0000115
annotated target: Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

rod like larval lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: BFO_0000051
      some values from: PATO_0001873
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
subclass of: larval body morphology variant
subclass of: larval lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: BFO_0000051
      some values from: PATO_0001873
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000023
IAO_0000115: Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell.
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Let
id: WBPhenotype:0000411

Axiom
annotated source: rod like larval lethal
annotated property: IAO_0000115
annotated target: Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell.
has db xref: WB:WBPaper00001366
has db xref: WB:WBPaper00002764
has db xref: WB:WBPerson2021

octanol chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_37868
subclass of: WBPhenotype_0001448
subclass of: WBPhenotype_0001452
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_37868
IAO_0000115: Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000412

Axiom
annotated source: octanol chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant.
has db xref: WB:WBPaper00002314

pharyngeal muscle paralyzed
type: Class
subclass of: WBPhenotype_0000980
IAO_0000115: Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000413

Axiom
annotated source: pharyngeal muscle paralyzed
annotated property: IAO_0000115
annotated target: Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation.
has db xref: WB:WBPerson557
has db xref: WB:cab

cell fate transformation
type: Class
subclass of: cell fate specification variant
IAO_0000115: The cell takes on a different identity from which it was initially committed.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000414

Axiom
annotated source: cell fate transformation
annotated property: IAO_0000115
annotated target: The cell takes on a different identity from which it was initially committed.
has db xref: GO:0045165
has db xref: WB:WBPaper00002924
has db xref: WB:WBPerson712

necrotic cell death variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0070265
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000729
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0070265
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
has narrow synonym: necrotic cell death abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000415

Axiom
annotated source: necrotic cell death variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
has db xref: GO:0070265
has db xref: WB:WBPerson712

yolk synthesis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007296
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001093
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007296
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas).
has narrow synonym: yolk synthesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: vitellogenin synthesis abnormal
id: WBPhenotype:0000416

Axiom
annotated source: yolk synthesis variant
annotated property: IAO_0000115
annotated target: Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell division failure
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000746
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051301
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The process of physical partitioning and separation of a cell into daughter cells is abolished.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000417

Axiom
annotated source: cell division failure
annotated property: IAO_0000115
annotated target: The process of physical partitioning and separation of a cell into daughter cells is abolished.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

intestinal cell division failure
type: Class
subclass of: cell division failure
IAO_0000115: The physical partitioning and separation of an intestinal cell into daughter cells is abolished.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000418

Axiom
annotated source: intestinal cell division failure
annotated property: IAO_0000115
annotated target: The physical partitioning and separation of an intestinal cell into daughter cells is abolished.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

L3 lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000035
subclass of: late larval lethal
subclass of: mid larval lethal
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000035
IAO_0000115: Animals die at the L3 stage of the life cycle.
has broad synonym: Let
has broad synonym: Lvl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000419

Axiom
annotated source: L3 lethal
annotated property: IAO_0000115
annotated target: Animals die at the L3 stage of the life cycle.
has db xref: WB:WBPerson2021

levamisole hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 6432
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000845
subclass of: WBPhenotype_0001579
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 6432
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: tetramisole hypersensitive
id: WBPhenotype:0000420

Axiom
annotated source: levamisole hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist.
has db xref: WB:WBPerson557

levamisole resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 6432
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000845
subclass of: WBPhenotype_0001502
subclass of: WBPhenotype_0001578
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 6432
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc.
has broad synonym: Lev R
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: tetramisole resistant
id: WBPhenotype:0000421

Axiom
annotated source: levamisole resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc.
has db xref: WB:WBPaper00000484
has db xref: WB:WBPerson2021

twitcher
type: Class
subclass of: WBPhenotype_0001701
IAO_0000115: Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000422

Axiom
annotated source: twitcher
annotated property: IAO_0000115
annotated target: Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion.
has db xref: WB:WBPaper00000484

head muscle contraction variant
type: Class
subclass of: muscle system physiology variant
IAO_0000115: Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control.
has narrow synonym: head muscle contraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000423

Axiom
annotated source: head muscle contraction variant
annotated property: IAO_0000115
annotated target: Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control.
has db xref: WB:WBPerson557

antibody staining variant
type: Class
subclass of: protein expression variant
IAO_0000115: Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has narrow synonym: antibody staining abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000424

Axiom
annotated source: antibody staining variant
annotated property: IAO_0000115
annotated target: Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

antibody staining reduced
type: Class
subclass of: antibody staining variant
IAO_0000115: Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000425

Axiom
annotated source: antibody staining reduced
annotated property: IAO_0000115
annotated target: Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

antibody staining increased
type: Class
subclass of: antibody staining variant
IAO_0000115: Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000426

Axiom
annotated source: antibody staining increased
annotated property: IAO_0000115
annotated target: Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no cuticle
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cuticle development variant
subclass of: WBPhenotype_0002558
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000427

Axiom
annotated source: no cuticle
annotated property: IAO_0000115
annotated target: Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

no adult cuticle
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002000
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
subclass of: no cuticle
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002000
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0005755
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
IAO_0000115: Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000428

Axiom
annotated source: no adult cuticle
annotated property: IAO_0000115
annotated target: Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

copulatory structure development variant
type: Class
subclass of: reproductive system development variant
IAO_0000115: Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control.
has narrow synonym: copulatory structure development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000429

Axiom
annotated source: copulatory structure development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male copulatory structure development variant
type: Class
subclass of: copulatory structure development variant
IAO_0000115: Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas).
has narrow synonym: male copulatory structure development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000430

Axiom
annotated source: male copulatory structure development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

hermaphrodite copulatory structure development variant
type: Class
subclass of: copulatory structure development variant
IAO_0000115: Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control.
has narrow synonym: hermaphrodite copulatory structure development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000431

Axiom
annotated source: hermaphrodite copulatory structure development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male copulatory structure absent
type: Class
subclass of: male copulatory structure development variant
IAO_0000115: Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000432

Axiom
annotated source: male copulatory structure absent
annotated property: IAO_0000115
annotated target: Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

DNA synthesis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006260
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000732
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0006260
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the processes involving the production of new DNA strands compared to control.
has narrow synonym: DNA synthesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000433

Axiom
annotated source: DNA synthesis variant
annotated property: IAO_0000115
annotated target: Variations in the processes involving the production of new DNA strands compared to control.
has db xref: GO:0006260
has db xref: WB:WBPerson2021

sexual maturation defective
type: Class
subclass of: reproductive system development variant
IAO_0000115: The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000434

Axiom
annotated source: sexual maturation defective
annotated property: IAO_0000115
annotated target: The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired.
has db xref: GO:0003006
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete protein localization abnormal
type: Class
IAO_0000115: OBSOLETE. Any change in the subcellular localization of a protein.
IAO_0100001: protein subcellular localization variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000435
deprecated: true

protein subcellular localization variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034613
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001408
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034613
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
has alternative id: WBPhenotype:0000435
has exact synonym: protein localization abnormal
has narrow synonym: protein subcellular localization abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000436

Axiom
annotated source: protein subcellular localization variant
annotated property: IAO_0000115
annotated target: Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
has db xref: WB:WBPerson557

obsolete heterochronic defect
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: developmental timing variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000437
deprecated: true

retarded heterochronic variations
type: Class
subclass of: developmental timing variant
IAO_0000115: Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000438

Axiom
annotated source: retarded heterochronic variations
annotated property: IAO_0000115
annotated target: Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
has db xref: GO:0040034
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

precocious heterochronic variations
type: Class
subclass of: developmental timing variant
IAO_0000115: Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000439

Axiom
annotated source: precocious heterochronic variations
annotated property: IAO_0000115
annotated target: Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
has db xref: GO:0040034
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

excretory canals long
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000573
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: excretory canal morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000573
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: long excretory canals
id: WBPhenotype:0000440

Axiom
annotated source: excretory canals long
annotated property: IAO_0000115
annotated target: The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

tail rounded
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000411
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: tail morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000411
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005741
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000441

Axiom
annotated source: tail rounded
annotated property: IAO_0000115
annotated target: Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

larval development retarded
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000750
subclass of: WBPhenotype_0000848
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0002164
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000442

Axiom
annotated source: larval development retarded
annotated property: IAO_0000115
annotated target: The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

spicule morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005312
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001024
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005312
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
has narrow synonym: spicule morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000443

Axiom
annotated source: spicule morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

bursa elongated
type: Class
subclass of: bursa morphology variant
IAO_0000115: The length of the adult male tail, including the lateral fan and rays, is extended compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000444

Axiom
annotated source: bursa elongated
annotated property: IAO_0000115
annotated target: The length of the adult male tail, including the lateral fan and rays, is extended compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

yolk synthesis in males
type: Class
subclass of: yolk synthesis variant
IAO_0000115: Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: vitellogenin synthesis in males
id: WBPhenotype:0000445

Axiom
annotated source: yolk synthesis in males
annotated property: IAO_0000115
annotated target: Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

supernumerary molt
type: Class
subclass of: WBPhenotype_0002041
IAO_0000115: Animals execute extra larval molts compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000446

Axiom
annotated source: supernumerary molt
annotated property: IAO_0000115
annotated target: Animals execute extra larval molts compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

adult development variant
type: Class
subclass of: postembryonic development variant
IAO_0000115: Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals.
has narrow synonym: adult development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000447

Axiom
annotated source: adult development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

adult cuticle development variant
type: Class
subclass of: adult development variant
IAO_0000115: Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas).
has narrow synonym: adult cuticle development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000448

Axiom
annotated source: adult cuticle development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

second adult cuticle
type: Class
subclass of: adult cuticle development variant
IAO_0000115: A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000449

Axiom
annotated source: second adult cuticle
annotated property: IAO_0000115
annotated target: A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells.
has db xref: WB:WBPaper00001439

obsolete swollen male tail
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: bursa swollen
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000450
deprecated: true

head protrusion
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
subclass of: head morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005739
IAO_0000115: Any irregular swelling in discrete regions of the head.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000451

Axiom
annotated source: head protrusion
annotated property: IAO_0000115
annotated target: Any irregular swelling in discrete regions of the head.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

tail protrusions
type: Class
subclass of: tail morphology variant
IAO_0000115: Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000452

Axiom
annotated source: tail protrusions
annotated property: IAO_0000115
annotated target: Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body protrusions
type: Class
subclass of: body morphology variant
IAO_0000115: Any irregular swelling in discrete regions of the body region between the head and the tail.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000453

Axiom
annotated source: body protrusions
annotated property: IAO_0000115
annotated target: Any irregular swelling in discrete regions of the body region between the head and the tail.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

head twisted
type: Class
subclass of: head morphology variant
IAO_0000115: The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000454

Axiom
annotated source: head twisted
annotated property: IAO_0000115
annotated target: The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

jerky movement
type: Class
subclass of: WBPhenotype_0001701
IAO_0000115: Animals exhibit abrupt transitions while traveling from one location to another.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000455

Axiom
annotated source: jerky movement
annotated property: IAO_0000115
annotated target: Animals exhibit abrupt transitions while traveling from one location to another.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

touch resistant
type: Class
subclass of: mechanosensation variant
IAO_0000115: Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: touch insensitive
id: WBPhenotype:0000456

Axiom
annotated source: touch resistant
annotated property: IAO_0000115
annotated target: Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals.
has db xref: WB:WBPerson557

organism starvation hypersensitive
type: Class
subclass of: organism starvation response variant
IAO_0000115: Animals show enhanced suceptibility to deprivation of nourishment, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000457

Axiom
annotated source: organism starvation hypersensitive
annotated property: IAO_0000115
annotated target: Animals show enhanced suceptibility to deprivation of nourishment, compared to control.
has db xref: WB:WBPerson2021

starvation resistant
type: Class
subclass of: organism starvation response variant
IAO_0000115: Animals show enhanced tolerance to deprivation of nourishment, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000458

Axiom
annotated source: starvation resistant
annotated property: IAO_0000115
annotated target: Animals show enhanced tolerance to deprivation of nourishment, compared to control.
has db xref: WB:WBPerson2021

pesticide response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25944
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25944
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals.
has narrow synonym: pesticide response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000459

Axiom
annotated source: pesticide response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals.
has db xref: WB:WBPerson557

paraquat response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1901562
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: pesticide response variant
subclass of: chemical response variant
subclass of: WBPhenotype_0001620
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1901562
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to paraquat compared to that observed in control animals.
has narrow synonym: paraquat response abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: methyl viologen response abnormal
id: WBPhenotype:0000460

Axiom
annotated source: paraquat response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to paraquat compared to that observed in control animals.
has db xref: WB:WBPerson557

paraquat resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_34905
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: paraquat response variant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_34905
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000461

Axiom
annotated source: paraquat resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

paraquat hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_34905
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: paraquat response variant
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_34905
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals.
has broad synonym: reactive oxygen species hypersensitive
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000462

Axiom
annotated source: paraquat hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

Axiom
annotated source: paraquat hypersensitive
annotated property: hasBroadSynonym
annotated target: reactive oxygen species hypersensitive
has db xref: WB:WBPaper00031296

metabolic pathway variant
type: Class
subclass of: organism metabolism processing variant
IAO_0000115: Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
has narrow synonym: metabolic pathway abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000463

Axiom
annotated source: metabolic pathway variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
has db xref: GO:0008152
has db xref: WB:WBPerson712

oxygen response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25805
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25805
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to oxygen compared to that observed in control animals.
has narrow synonym: oxygen response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000464

Axiom
annotated source: oxygen response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to oxygen compared to that observed in control animals.
has db xref: WB:WBPerson557

high oxygen resistant
type: Class
subclass of: oxygen response variant
IAO_0000115: Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000465

Axiom
annotated source: high oxygen resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals.
has db xref: WB:WBPerson2021

high oxygen hypersensitive
type: Class
subclass of: oxygen response variant
IAO_0000115: Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000466

Axiom
annotated source: high oxygen hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control.
has db xref: GO:0055093
has db xref: WB:WBPerson2021

age associated fluorescence increased
type: Class
subclass of: WBPhenotype_0001009
IAO_0000115: Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000467

Axiom
annotated source: age associated fluorescence increased
annotated property: IAO_0000115
annotated target: Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
has db xref: WB:WBPaper00033040
has db xref: WB:WBPerson2021

age associated fluorescence reduced
type: Class
subclass of: WBPhenotype_0001009
IAO_0000115: Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000468

Axiom
annotated source: age associated fluorescence reduced
annotated property: IAO_0000115
annotated target: Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
has db xref: WB:WBPerson2021

Q neuroblast lineage migration variant
type: Class
subclass of: WBPhenotype_0001140
IAO_0000115: The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals.
has narrow synonym: Q neuroblast lineage migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000469

Axiom
annotated source: Q neuroblast lineage migration variant
annotated property: IAO_0000115
annotated target: The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals.
has db xref: WB:WBPaper00001954
has db xref: WB:WBPaper00031356
has db xref: WB:WBPerson712

HSN migration variant
type: Class
subclass of: WBPhenotype_0001229
IAO_0000115: Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals.
has narrow synonym: HSN migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000470

Axiom
annotated source: HSN migration variant
annotated property: IAO_0000115
annotated target: Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals.
has db xref: WB:WBPaper00001836
has db xref: WB:WBPerson2021

ALM migration variant
type: Class
subclass of: WBPhenotype_0001520
IAO_0000115: Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals.
has narrow synonym: ALM migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000471

Axiom
annotated source: ALM migration variant
annotated property: IAO_0000115
annotated target: Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals.
has db xref: WB:WBPaper00001304
has db xref: WB:WBPaper00003058
has db xref: WB:WBPerson2021

endoderm absent
type: Class
subclass of: WBPhenotype_0000749
IAO_0000115: Animals lack the early blast cells that give rise to the gut tissue (Wormatlas).
has exact synonym: gutless
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000472

Axiom
annotated source: endoderm absent
annotated property: IAO_0000115
annotated target: Animals lack the early blast cells that give rise to the gut tissue (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

progressive paralysis
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000763
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001818
subclass of: paralyzed
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000763
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001818
IAO_0000115: Animals become increasingly sluggish/immobilized as they age.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000473

Axiom
annotated source: progressive paralysis
annotated property: IAO_0000115
annotated target: Animals become increasingly sluggish/immobilized as they age.
has db xref: WB:WBPaper00001709

muscle attachment variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016203
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: muscle system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016203
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
has broad synonym: Mua
has narrow synonym: muscle attachment abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000474

Axiom
annotated source: muscle attachment variant
annotated property: IAO_0000115
annotated target: Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

muscle detached
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
subclass of: muscle attachment variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
IAO_0000115: Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000475

Axiom
annotated source: muscle detached
annotated property: IAO_0000115
annotated target: Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

progressive muscle detachment
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001818
subclass of: muscle detached
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001453
    intersection of: Restriction
      on property: BFO_0000070
      some values from: WBbt_0003675
    intersection of: Restriction
      on property: has quality
      some values from: PATO_0001818
IAO_0000115: The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000476

Axiom
annotated source: progressive muscle detachment
annotated property: IAO_0000115
annotated target: The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nucleolus refraction variant
type: Class
subclass of: WBPhenotype_0000722
IAO_0000115: Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus.
has narrow synonym: nucleolus refraction abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000477

Axiom
annotated source: nucleolus refraction variant
annotated property: IAO_0000115
annotated target: Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

isothermal tracking behavior variant
type: Class
subclass of: WBPhenotype_0002513
IAO_0000115: Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature.
has narrow synonym: isothermal tracking behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: thermotaxis abnormal
id: WBPhenotype:0000478
in subset: phenotype slim wb

Axiom
annotated source: isothermal tracking behavior variant
annotated property: IAO_0000115
annotated target: Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature.
has db xref: WB:WBPaper00002214

egg pale
type: Class
subclass of: WBPhenotype_0000970
subclass of: WBPhenotype_0001261
IAO_0000115: Eggs show deficiencies in chroma resulting in increased translucency.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000479

Axiom
annotated source: egg pale
annotated property: IAO_0000115
annotated target: Eggs show deficiencies in chroma resulting in increased translucency.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

pyrazine chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_30953
subclass of: WBPhenotype_0001438
subclass of: WBPhenotype_0001474
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_30953
IAO_0000115: Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000480

Axiom
annotated source: pyrazine chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant.
has db xref: WB:WBPaper00001786

negative chemotaxis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001434
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals.
has narrow synonym: negative chemotaxis abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: chemical avoidance abnormal
has related synonym: chemoaversion abnormal
id: WBPhenotype:0000481

Axiom
annotated source: negative chemotaxis variant
annotated property: IAO_0000115
annotated target: Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals.
has db xref: GO:0050919
has db xref: WB:cab

garlic chemotaxis defective
type: Class
subclass of: WBPhenotype_0001449
subclass of: WBPhenotype_0001451
IAO_0000115: Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000482

Axiom
annotated source: garlic chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent.
has db xref: WB:WBPaper00001374

no gut granules
type: Class
subclass of: gut granule development variant
IAO_0000115: Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000483

Axiom
annotated source: no gut granules
annotated property: IAO_0000115
annotated target: Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

embryo small
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000587
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
subclass of: WBPhenotype_0001136
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000587
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000003
IAO_0000115: The organism's size during the embryonic developmental stage is decreased compared to that observed in control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000484

Axiom
annotated source: embryo small
annotated property: IAO_0000115
annotated target: The organism's size during the embryonic developmental stage is decreased compared to that observed in control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dauer death increased
type: Class
subclass of: WBPhenotype_0002527
IAO_0000115: The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: reduced dauer survival
id: WBPhenotype:0000485

Axiom
annotated source: dauer death increased
annotated property: IAO_0000115
annotated target: The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

colchicine hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23359
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23359
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000486

Axiom
annotated source: colchicine hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

colchicine resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23359
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_23359
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000487

Axiom
annotated source: colchicine resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

chloroquine hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 3638
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 3638
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000488

Axiom
annotated source: chloroquine hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

chloroquine resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 3638
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI 3638
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000489

Axiom
annotated source: chloroquine resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

pharynx disorganized
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003681
subclass of: pharyngeal development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003681
IAO_0000115: The components of the feeding organ fail to be arranged in the same manner as control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000490

Axiom
annotated source: pharynx disorganized
annotated property: IAO_0000115
annotated target: The components of the feeding organ fail to be arranged in the same manner as control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

isthmus morphology defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003734
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000709
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003734
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any observed morphological defects of the isthmus.
has narrow synonym: isthmus morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: isthmus malformed
id: WBPhenotype:0000491

Axiom
annotated source: isthmus morphology defective
annotated property: IAO_0000115
annotated target: Any observed morphological defects of the isthmus.
has db xref: WB:WBPerson2021

corpus morphology defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003733
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000709
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003733
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas).
has narrow synonym: corpus morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: corpus malformed
id: WBPhenotype:0000492

Axiom
annotated source: corpus morphology defective
annotated property: IAO_0000115
annotated target: Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas).
has db xref: WB:WBPerson2021

metacorpus morphology defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003711
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000709
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003711
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the form, structure or composition of the first pharyngeal bulb compared to control.
has narrow synonym: metacorpus morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: metacarpas malformed
id: WBPhenotype:0000493

Axiom
annotated source: metacorpus morphology defective
annotated property: IAO_0000115
annotated target: Any variation in the form, structure or composition of the first pharyngeal bulb compared to control.
has db xref: WB:WBPerson2021

two fold arrest
type: Class
subclass of: WBPhenotype_0000779
IAO_0000115: Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000494

Axiom
annotated source: two fold arrest
annotated property: IAO_0000115
annotated target: Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo.
has db xref: WB:WBPerson101

ray ectopic
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000628
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: male tail sensory ray development variant
subclass of: WBPhenotype_0002498
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000628
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000495

Axiom
annotated source: ray ectopic
annotated property: IAO_0000115
annotated target: Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male postdeirid sensilla absent
type: Class
subclass of: WBPhenotype_0001008
IAO_0000115: Males lack the specialized sensory papillae that lie along the posterior half of the body.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000496

Axiom
annotated source: male postdeirid sensilla absent
annotated property: IAO_0000115
annotated target: Males lack the specialized sensory papillae that lie along the posterior half of the body.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism gamma ray response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010332
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism ionizing radiation response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010332
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
has narrow synonym: organism gamma ray response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000497

Axiom
annotated source: organism gamma ray response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
has db xref: WB:WBPerson557

methyl methanesulfonate response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25255
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_25255
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals.
has narrow synonym: methyl methanesulfonate response abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: MMS response abnormal
id: WBPhenotype:0000498

Axiom
annotated source: methyl methanesulfonate response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals.
has db xref: WB:WBPerson557

ethyl methanesulfonate response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_23994
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_23994
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals.
has narrow synonym: ethyl methanesulfonate response abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: EMS response abnormal
id: WBPhenotype:0000499

Axiom
annotated source: ethyl methanesulfonate response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals.
has db xref: WB:WBPerson557

acetylcholinesterase inhibitor hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38462
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: WBPhenotype_0001290
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38462
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000500

Axiom
annotated source: acetylcholinesterase inhibitor hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

left handed roller
type: Class
subclass of: roller
IAO_0000115: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Rol
id: WBPhenotype:0000501

Axiom
annotated source: left handed roller
annotated property: IAO_0000115
annotated target: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

right handed roller
type: Class
subclass of: roller
IAO_0000115: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar.
has broad synonym: Rol
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000502

Axiom
annotated source: right handed roller
annotated property: IAO_0000115
annotated target: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

endoreduplication variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042023
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: DNA synthesis variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042023
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas).
has narrow synonym: endoreduplication abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000503

Axiom
annotated source: endoreduplication variant
annotated property: IAO_0000115
annotated target: Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nuclear division variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000280
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000280
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control.
has narrow synonym: nuclear division abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: karyokinesis abnormal
id: WBPhenotype:0000504
in subset: phenotype slim wb
comment: Possible XP.

Axiom
annotated source: nuclear division variant
annotated property: IAO_0000115
annotated target: Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

male ray morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: sensillum morphology variant
subclass of: WBPhenotype_0001358
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006941
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye.
has broad synonym: Ram
has narrow synonym: male ray morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000505

Axiom
annotated source: male ray morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye.
has db xref: WB:WBPaper00000932
has db xref: WB:WBPaper00001328
has db xref: WB:WBPaper00002149
has db xref: WB:WBPaper00029016
has db xref: WB:WBPerson712

bursa swollen
type: Class
subclass of: bursa morphology variant
IAO_0000115: The adult male tail, including the lateral fan and rays, appears bloated or distended.
has exact synonym: swollen male tail
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000506

Axiom
annotated source: bursa swollen
annotated property: IAO_0000115
annotated target: The adult male tail, including the lateral fan and rays, appears bloated or distended.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

acetylcholine levels variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_15355
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism metabolism processing variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_15355
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline.
has narrow synonym: acetylcholine levels abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000507

Axiom
annotated source: acetylcholine levels variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nonsense mRNA accumulation
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000184
subclass of: organism metabolism processing variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0000184
IAO_0000115: Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000508

Axiom
annotated source: nonsense mRNA accumulation
annotated property: IAO_0000115
annotated target: Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail.
has db xref: GO:0070478
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

sperm pseudopod variant
type: Class
subclass of: sperm morphology variant
IAO_0000115: Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa.
has narrow synonym: sperm pseudopod abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000509

Axiom
annotated source: sperm pseudopod variant
annotated property: IAO_0000115
annotated target: Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa.
has db xref: WB:WBPaper00001075
has db xref: WB:WBPerson2021

vulval invagination variant L4
type: Class
subclass of: vulva morphology variant
subclass of: vulva development variant
IAO_0000115: The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered.
has alternative id: WBPhenotype:0000287
has narrow synonym: vulval invagination L4 abnormal
has narrow synonym: vulval invagination abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: vulval invagination L4 variant
id: WBPhenotype:0000510

Axiom
annotated source: vulval invagination variant L4
annotated property: IAO_0000115
annotated target: The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered.
has db xref: WB:WBPaper00001738
has db xref: WB:WBPerson2021

nuclear positioning variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007097
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell physiology phenotype
subclass of: WBPhenotype_0001344
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007097
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the directed movement of the nucleus to a specific location within a cell compared to control.
has narrow synonym: nuclear positioning abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: nuclear migration variant
id: WBPhenotype:0000511
in subset: phenotype slim wb
comment: Possible XP.

Axiom
annotated source: nuclear positioning variant
annotated property: IAO_0000115
annotated target: Variations in the directed movement of the nucleus to a specific location within a cell compared to control.
has db xref: GO:0007097
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

VNC nuclear positioning variant
type: Class
subclass of: nuclear positioning variant
IAO_0000115: Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position.
has narrow synonym: VNC nuclear positioning abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: VNC nuclear migration variant
id: WBPhenotype:0000512

Axiom
annotated source: VNC nuclear positioning variant
annotated property: IAO_0000115
annotated target: Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position.
has db xref: WB:WBPaper00031891
has db xref: WB:WBPerson712

obsolete touch response abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: mechanosensation variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000513
deprecated: true

rubber band
type: Class
subclass of: mechanosensation variant
IAO_0000115: When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding.
has broad synonym: Rbr
has exact synonym: rubberband
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000514

Axiom
annotated source: rubber band
annotated property: IAO_0000115
annotated target: When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding.
has db xref: WB:WBPaper00006135
has db xref: WB:WBPerson2021

ventral nerve cord development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000945
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord.
has narrow synonym: ventral nerve cord development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000515

Axiom
annotated source: ventral nerve cord development variant
annotated property: IAO_0000115
annotated target: Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord.
has db xref: WB:WBPerson557

ventral cord disorganized
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005829
subclass of: WBPhenotype_0000976
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000937
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005829
IAO_0000115: The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000516

Axiom
annotated source: ventral cord disorganized
annotated property: IAO_0000115
annotated target: The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

behavior phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007610
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007610
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals.
has exact synonym: behavior abnormal
has exact synonym: behavior variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000517

Axiom
annotated source: behavior phenotype
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals.
has db xref: GO:0007610
has db xref: WB:WBPerson557

development phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals.
has exact synonym: development abnormal
has exact synonym: development variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000518

Axiom
annotated source: development phenotype
annotated property: IAO_0000115
annotated target: Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals.
has db xref: GO:0032502
has db xref: WB:WBPerson2021

physiology phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008150
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000886
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008150
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals.
has exact synonym: physiology abnormal
has exact synonym: physiology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000519

Axiom
annotated source: physiology phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals.
has db xref: WB:WBPerson712

morphology phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0002551
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0002314
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals.
has exact synonym: morphology abnormal
has exact synonym: morphology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000520

Axiom
annotated source: morphology phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals.
has db xref: WB:WBPerson712

pigmentation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: morphology phenotype
subclass of: WBPhenotype_0002555
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency.
has exact synonym: pigmentation abnormal
has exact synonym: pigmentation variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000521
in subset: phenotype slim wb

Axiom
annotated source: pigmentation phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

organism region behavior variant
type: Class
subclass of: organism behavior variant
IAO_0000115: Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals.
has narrow synonym: organism region behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000522

Axiom
annotated source: organism region behavior variant
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

chemical response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042221
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0042221
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.
has narrow synonym: chemical response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000523

Axiom
annotated source: chemical response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.
has db xref: WB:WBPerson557

bleach response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1901530
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001379
subclass of: WBPhenotype_0001620
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_1901530
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to bleach compared to that observed in control animals.
has narrow synonym: bleach response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000524

Axiom
annotated source: bleach response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to bleach compared to that observed in control animals.
has db xref: WB:WBPerson557

organism behavior variant
type: Class
subclass of: behavior phenotype
IAO_0000115: Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms.
has narrow synonym: organism behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000525
in subset: phenotype slim wb

Axiom
annotated source: organism behavior variant
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms.
has db xref: GO:0007610
has db xref: WB:WBPerson557

cell pigmentation phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: pigmentation phenotype
subclass of: cell morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0002247
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell.
has exact synonym: cell pigmentation abnormal
has exact synonym: cell pigmentation variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000526
in subset: phenotype slim wb

Axiom
annotated source: cell pigmentation phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell.
has db xref: WB:WBPerson557

organism pigmentation phenotype
type: Class
subclass of: pigmentation phenotype
IAO_0000115: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism.
has exact synonym: organism pigmentation abnormal
has exact synonym: organism pigmentation variant
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Abnormal Coloration
id: WBPhenotype:0000527
in subset: phenotype slim wb

Axiom
annotated source: organism pigmentation phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism.
has db xref: WB:WBPerson557

body region development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
has narrow synonym: body region development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000528

Axiom
annotated source: body region development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048468
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: development phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048468
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals.
has narrow synonym: cell development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000529
in subset: phenotype slim wb

Axiom
annotated source: cell development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals.
has db xref: GO:0048468
has db xref: WB:cab

organ system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: development phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals.
has narrow synonym: organ system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000530
in subset: phenotype slim wb

Axiom
annotated source: organ system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals.
has db xref: GO:0048731
has db xref: WB:cab

organism development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: development phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control.
has narrow synonym: organism development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000531
in subset: phenotype slim wb

Axiom
annotated source: organism development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control.
has db xref: WB:cab

body region morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005738
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism morphology variant
subclass of: WBPhenotype_0002557
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005738
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals.
has narrow synonym: body region morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000532

Axiom
annotated source: body region morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

cell morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: morphology phenotype
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0004017
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
has narrow synonym: cell morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000533
in subset: phenotype slim wb

Axiom
annotated source: cell morphology variant
annotated property: IAO_0000115
annotated target: Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
has db xref: GO:0005623
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organ system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005746
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: morphology phenotype
subclass of: WBPhenotype_0002554
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005746
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system.
has narrow synonym: organ system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000534
in subset: phenotype slim wb

Axiom
annotated source: organ system morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system.
has db xref: WB:WBPerson557

organism morphology variant
type: Class
subclass of: morphology phenotype
IAO_0000115: Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals.
has broad synonym: Bmd
has narrow synonym: organism morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body morphology defects
id: WBPhenotype:0000535
in subset: phenotype slim wb

Axiom
annotated source: organism morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00004403
has db xref: WB:WBPaper00004651
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:cab

cell physiology phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals.
has exact synonym: cell physiology abnormal
has exact synonym: cell physiology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000536
in subset: phenotype slim wb

Axiom
annotated source: cell physiology phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0009987

obsolete synaptic input abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: synaptic transmission variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000537
deprecated: true

obsolete synaptic output abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: synaptic transmission variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000538
deprecated: true

dorsal nerve cord development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000945
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas).
has narrow synonym: dorsal nerve cord development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000539

Axiom
annotated source: dorsal nerve cord development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

muscle arm development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body wall cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas).
has narrow synonym: muscle arm development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: muscle arm extension variant
id: WBPhenotype:0000540

Axiom
annotated source: muscle arm development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

cord commissures fail to reach target
type: Class
subclass of: cord commissures variant
IAO_0000115: Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000541

Axiom
annotated source: cord commissures fail to reach target
annotated property: IAO_0000115
annotated target: Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPaper00028984
has db xref: WB:WBPerson712

fat
type: Class
subclass of: WBPhenotype_0001727
IAO_0000115: Animals exhibit an increased girth compared to a control animal of the same developmental stage.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: increased girth
has related synonym: thick
id: WBPhenotype:0000542

Axiom
annotated source: fat
annotated property: IAO_0000115
annotated target: Animals exhibit an increased girth compared to a control animal of the same developmental stage.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

forward kinker
type: Class
subclass of: kinker
IAO_0000115: Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000543

Axiom
annotated source: forward kinker
annotated property: IAO_0000115
annotated target: Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

backward kinker
type: Class
subclass of: kinker
IAO_0000115: Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000544

Axiom
annotated source: backward kinker
annotated property: IAO_0000115
annotated target: Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

egg retention
type: Class
subclass of: egg laying defective
IAO_0000115: Eggs are retained in the uterus at a later stage when compared with control animals.
has broad synonym: Ret
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: late eggs laid
id: WBPhenotype:0000545

Axiom
annotated source: egg retention
annotated property: IAO_0000115
annotated target: Eggs are retained in the uterus at a later stage when compared with control animals.
has db xref: WB:cab

early eggs laid
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000694
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
subclass of: hyperactive egg laying
subclass of: precocious heterochronic variations
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000694
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
IAO_0000115: Eggs are laid at an earlier stage of development when compared with control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000546

Axiom
annotated source: early eggs laid
annotated property: IAO_0000115
annotated target: Eggs are laid at an earlier stage of development when compared with control animals.
has db xref: WB:cab

starved
type: Class
subclass of: organism homeostasis metabolism variant
IAO_0000115: Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Eat
id: WBPhenotype:0000547

Axiom
annotated source: starved
annotated property: IAO_0000115
annotated target: Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals.
has db xref: WB:WBPaper00001709
has db xref: WB:WBPerson2021

muscle dystrophy
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001780
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003675
subclass of: muscle system physiology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001780
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0003675
IAO_0000115: Progressive degeneration of muscle.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000548

Axiom
annotated source: muscle dystrophy
annotated property: IAO_0000115
annotated target: Progressive degeneration of muscle.
has db xref: WB:cab

head muscle dystrophy
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001780
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006761
subclass of: muscle dystrophy
subclass of: WBPhenotype_0001002
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001780
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006761
IAO_0000115: Progressive degeneration of the head muscle.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000549

Axiom
annotated source: head muscle dystrophy
annotated property: IAO_0000115
annotated target: Progressive degeneration of the head muscle.
has db xref: WB:cab

body muscle dystrophy
type: Class
subclass of: muscle dystrophy
subclass of: body behavior variant
IAO_0000115: Progressive degeneration of muscle along the body wall.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body wall muscle dystrophy
id: WBPhenotype:0000550

Axiom
annotated source: body muscle dystrophy
annotated property: IAO_0000115
annotated target: Progressive degeneration of muscle along the body wall.
has db xref: WB:cab

omega turns variant
type: Class
subclass of: WBPhenotype_0002311
IAO_0000115: Animals exhibit variations in the rate of sharp head to tail turns compared to control animals.
has narrow synonym: omega turns abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000551

Axiom
annotated source: omega turns variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the rate of sharp head to tail turns compared to control animals.
has db xref: WB:WBPaper00000075
has db xref: WB:WBPaper00006375
has db xref: WB:WBPerson712

GABA levels variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_16865
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism metabolism processing variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000070
    intersection of: Restriction
      on property: RO_0000052
      some values from: CHEBI_16865
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the amount of GABA compared to control animals at a defined stage.
has narrow synonym: GABA levels abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000552

Axiom
annotated source: GABA levels variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the amount of GABA compared to control animals at a defined stage.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

muscle birefringence variant
type: Class
subclass of: WBPhenotype_0000926
IAO_0000115: Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics.
has alternative id: WBPhenotype:0000714
has exact synonym: Dim
has exact synonym: disorganized muscle
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: muscle birefringence abnormal
id: WBPhenotype:0000553
comment: Disorganized muscle fibers display a weak and abnormal birefringency pattern when examined using polarized optics.

Axiom
annotated source: muscle birefringence variant
annotated property: IAO_0000115
annotated target: Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics.
has db xref: WB:WBPerson557

hypoosmotic shock hypersensitive
type: Class
subclass of: osmotic integrity variant
IAO_0000115: Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000554

Axiom
annotated source: hypoosmotic shock hypersensitive
annotated property: IAO_0000115
annotated target: Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode.
has db xref: WB:WBPaper00000484
has db xref: WB:WBPerson2021

drug adaptation variant
type: Class
subclass of: drug response variant
IAO_0000115: Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control.
has narrow synonym: drug adaptation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000555

Axiom
annotated source: drug adaptation variant
annotated property: IAO_0000115
annotated target: Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dopamine adaptation variant
type: Class
subclass of: drug adaptation variant
IAO_0000115: Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control.
has narrow synonym: dopamine adaptation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000556

Axiom
annotated source: dopamine adaptation variant
annotated property: IAO_0000115
annotated target: Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dopamine adaptation defective
type: Class
subclass of: dopamine adaptation variant
IAO_0000115: Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000557

Axiom
annotated source: dopamine adaptation defective
annotated property: IAO_0000115
annotated target: Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

calcium channel modulator response variant
type: Class
subclass of: drug response variant
subclass of: WBPhenotype_0001833
subclass of: WBPhenotype_0002170
IAO_0000115: Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
has narrow synonym: calcium channel modulator response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000558

Axiom
annotated source: calcium channel modulator response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
has db xref: WB:WBPerson557

calcium channel modulator hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38808
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug hypersensitive
subclass of: calcium channel modulator response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38808
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000559

Axiom
annotated source: calcium channel modulator hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

calcium channel modulator resistant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38808
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug resistant
subclass of: calcium channel modulator response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_38808
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000560

Axiom
annotated source: calcium channel modulator resistant
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
has db xref: WB:WBPerson557

head levamisole resistant
type: Class
subclass of: levamisole resistant
IAO_0000115: The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: head tetramisole resistant
id: WBPhenotype:0000561

Axiom
annotated source: head levamisole resistant
annotated property: IAO_0000115
annotated target: The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals.
has db xref: WB:WBPaper00000484

body levamisole resistant
type: Class
subclass of: levamisole resistant
IAO_0000115: The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: body tetramisole resistant
id: WBPhenotype:0000562

Axiom
annotated source: body levamisole resistant
annotated property: IAO_0000115
annotated target: The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals.
has db xref: WB:WBPaper00000484

shrinker
type: Class
subclass of: WBPhenotype_0001701
IAO_0000115: The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000563

Axiom
annotated source: shrinker
annotated property: IAO_0000115
annotated target: The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

echo defecation cycle
type: Class
subclass of: defecation cycle variant
IAO_0000115: Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000564

Axiom
annotated source: echo defecation cycle
annotated property: IAO_0000115
annotated target: Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals.
has db xref: WB:WBPaper00002305
has db xref: WB:WBPaper00003765
has db xref: WB:WBPerson712

coiler
type: Class
subclass of: WBPhenotype_0002297
subclass of: WBPhenotype_0004017
IAO_0000115: The body of an animal assumes a coil-like shape when it attempts to move.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: curler
id: WBPhenotype:0000565

Axiom
annotated source: coiler
annotated property: IAO_0000115
annotated target: The body of an animal assumes a coil-like shape when it attempts to move.
has db xref: WB:WBPerson363

ventral coiler
type: Class
subclass of: coiler
IAO_0000115: A coiling body that bends ventrally.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: ventral curler
id: WBPhenotype:0000566

Axiom
annotated source: ventral coiler
annotated property: IAO_0000115
annotated target: A coiling body that bends ventrally.
has db xref: WB:WBPerson363

dorsal coiler
type: Class
subclass of: coiler
IAO_0000115: A coiling body that bends dorsally.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: dorsal curler
id: WBPhenotype:0000567

Axiom
annotated source: dorsal coiler
annotated property: IAO_0000115
annotated target: A coiling body that bends dorsally.
has db xref: WB:WBperson363

axon ultrastructure variant
type: Class
subclass of: axon morphology variant
IAO_0000115: Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals.
has narrow synonym: axon ultrastructure abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000568

Axiom
annotated source: axon ultrastructure variant
annotated property: IAO_0000115
annotated target: Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPerson712

axon varicosities
type: Class
subclass of: axon ultrastructure variant
IAO_0000115: Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000569

Axiom
annotated source: axon varicosities
annotated property: IAO_0000115
annotated target: Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPaper00024595
has db xref: WB:WBPerson712

axon cisternae
type: Class
subclass of: axon ultrastructure variant
IAO_0000115: Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000570

Axiom
annotated source: axon cisternae
annotated property: IAO_0000115
annotated target: Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPaper00024595
has db xref: WB:WBPerson712

axon vesicle variant
type: Class
subclass of: axon ultrastructure variant
IAO_0000115: Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals.
has narrow synonym: abnormal axon vesicle
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000571

Axiom
annotated source: axon vesicle variant
annotated property: IAO_0000115
annotated target: Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals.
has db xref: WB:WBPaper00001499
has db xref: WB:WBPerson712

neuronal outgrowth variant
type: Class
subclass of: WBPhenotype_0000816
IAO_0000115: Any variation in the processes that govern the extension of neuronal projections.
has narrow synonym: neuronal outgrowth abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000572

Axiom
annotated source: neuronal outgrowth variant
annotated property: IAO_0000115
annotated target: Any variation in the processes that govern the extension of neuronal projections.
has db xref: WB:WBPerson2021

obsolete neuronal branching variant
type: Class
IAO_0000115: OBSOLETE.
consider: axon branching variant
consider: WBPhenotype_0001398
has narrow synonym: neuronal branching abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000573
deprecated: true

Axiom
annotated source: obsolete neuronal branching variant
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

excretory canal short
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: excretory canal morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000574
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000574

Axiom
annotated source: excretory canal short
annotated property: IAO_0000115
annotated target: The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organ system physiology phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control.
has exact synonym: organ system physiology abnormal
has exact synonym: organ system physiology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000575
in subset: phenotype slim wb

Axiom
annotated source: organ system physiology phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control.
has db xref: GO:0003008

organism physiology phenotype
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli.
has exact synonym: organism physiology abnormal
has exact synonym: organism physiology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000576
in subset: phenotype slim wb

Axiom
annotated source: organism physiology phenotype
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli.
has db xref: WB:WBPerson712

organism homeostasis metabolism variant
type: Class
subclass of: organism physiology phenotype
IAO_0000115: Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.
has narrow synonym: organism homeostasis metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000577
in subset: phenotype slim wb

Axiom
annotated source: organism homeostasis metabolism variant
annotated property: IAO_0000115
annotated target: Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.
has db xref: GO:0048871
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body axis development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body region development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals.
has narrow synonym: body axis development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000578

Axiom
annotated source: body axis development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism segment development variant
type: Class
subclass of: organism development variant
IAO_0000115: Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
has narrow synonym: organism segment development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000579

Axiom
annotated source: organism segment development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism segment behavior variant
type: Class
subclass of: organism region behavior variant
IAO_0000115: Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals.
has narrow synonym: organism segment behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000580

Axiom
annotated source: organism segment behavior variant
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

body axis morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005768
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: body region morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005768
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals.
has narrow synonym: body axis morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000581

Axiom
annotated source: body axis morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism segment morphology variant
type: Class
subclass of: organism morphology variant
IAO_0000115: Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals.
has narrow synonym: organism segment morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000582

Axiom
annotated source: organism segment morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dumpy
type: Class
subclass of: WBPhenotype_0001726
subclass of: WBPhenotype_0001727
IAO_0000115: Worms are shorter and stouter than control animals at the same developmental stage.
has broad synonym: Dpy
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000583

Axiom
annotated source: dumpy
annotated property: IAO_0000115
annotated target: Worms are shorter and stouter than control animals at the same developmental stage.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00004403
has db xref: WB:WBPaper00004651
has db xref: WB:WBPaper00005654
has db xref: WB:WBPaper00006395
has db xref: WB:WBPaper00024497
has db xref: WB:cab
has db xref: WB:cgc31

synaptic transmission variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007268
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0002020
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007268
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals.
has alternative id: WBPhenotype:0000537
has alternative id: WBPhenotype:0000538
has exact synonym: synaptic input variant
has exact synonym: synaptic output variant
has narrow synonym: synaptic input abnormal
has narrow synonym: synaptic output abnormal
has narrow synonym: synaptic transmission abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000584

Axiom
annotated source: synaptic transmission variant
annotated property: IAO_0000115
annotated target: Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals.
has db xref: GO:0007268
has db xref: WB:cab

cell homeostasis metabolism variant
type: Class
subclass of: cell physiology phenotype
IAO_0000115: Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.
has narrow synonym: cell homeostasis metabolism abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000585
in subset: phenotype slim wb

Axiom
annotated source: cell homeostasis metabolism variant
annotated property: IAO_0000115
annotated target: Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.
has db xref: GO:0019725
has db xref: WB:WBPerson2021

bleach hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_29222
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: bleach response variant
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_29222
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000586

Axiom
annotated source: bleach hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

obsolete lectin staining variant
type: Class
IAO_0000115: OBSOLETE.
consider: WBPhenotype_0002072
has narrow synonym: lectin staining abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000587
deprecated: true

Axiom
annotated source: obsolete lectin staining variant
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

obsolete no male variantity scored
type: Class
IAO_0000115: OBSOLETE.
has narrow synonym: no male abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000588
comment: This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
deprecated: true

Axiom
annotated source: obsolete no male variantity scored
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

obsolete no hermaphrodite variantity scored
type: Class
IAO_0000115: OBSOLETE.
has narrow synonym: no hermaphrodite abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000589
comment: This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
deprecated: true

Axiom
annotated source: obsolete no hermaphrodite variantity scored
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

cell corpse number variant
type: Class
subclass of: WBPhenotype_0000730
IAO_0000115: Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage.
has narrow synonym: cell corpse number abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000590

Axiom
annotated source: cell corpse number variant
annotated property: IAO_0000115
annotated target: Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage.
has db xref: WB:WBPerson712

metal response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_33521
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_33521
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
has narrow synonym: metal response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000591

Axiom
annotated source: metal response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
has db xref: WB:WBPerson557

copper response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_30052
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: metal response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI_30052
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to copper compared to that observed in control animals.
has narrow synonym: copper response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000592

Axiom
annotated source: copper response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to copper compared to that observed in control animals.
has db xref: WB:WBPerson557

copper hypersensitive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28694
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: copper response variant
subclass of: WBPhenotype_0001918
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001651
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28694
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals respond to copper at a lower concentration or a shorter exposure compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000593

Axiom
annotated source: copper hypersensitive
annotated property: IAO_0000115
annotated target: Animals respond to copper at a lower concentration or a shorter exposure compared to control animals.
has db xref: WB:WBPerson557

cell migration variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016477
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016477
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the orderly movement of a cell from one site to another.
has broad synonym: Mig
has narrow synonym: cell migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: migration of cells abnormal
id: WBPhenotype:0000594
in subset: phenotype slim wb

Axiom
annotated source: cell migration variant
annotated property: IAO_0000115
annotated target: Any variation in the orderly movement of a cell from one site to another.
has db xref: GO:0016477
has db xref: WB:cab

head behavior variant
type: Class
subclass of: organism segment behavior variant
IAO_0000115: Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals.
has narrow synonym: head behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000595

Axiom
annotated source: head behavior variant
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:cab

body behavior variant
type: Class
subclass of: organism segment behavior variant
IAO_0000115: Activity characteristic of the body is altered compared to control.
has narrow synonym: body behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000596

Axiom
annotated source: body behavior variant
annotated property: IAO_0000115
annotated target: Activity characteristic of the body is altered compared to control.
has db xref: WB:cab

tail behavior variant
type: Class
subclass of: organism segment behavior variant
IAO_0000115: Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals.
has narrow synonym: tail behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000597

Axiom
annotated source: tail behavior variant
annotated property: IAO_0000115
annotated target: Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alimentary system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas).
has narrow synonym: alimentary system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000598
in subset: phenotype slim wb

Axiom
annotated source: alimentary system morphology variant
annotated property: IAO_0000115
annotated target: Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

coelomic system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005749
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005749
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ.
has narrow synonym: coelomic system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000599
in subset: phenotype slim wb

Axiom
annotated source: coelomic system morphology variant
annotated property: IAO_0000115
annotated target: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

epithelial system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005730
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005730
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control.
has narrow synonym: epithelial system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000600
in subset: phenotype slim wb

Axiom
annotated source: epithelial system morphology variant
annotated property: IAO_0000115
annotated target: Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

excretory secretory system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005736
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005736
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas).
has alternative id: WBPhenotype:0000602
has exact synonym: excretory system morphology variant
has narrow synonym: excretory secretory system morphology abnormal
has narrow synonym: excretory system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000601
in subset: phenotype slim wb

Axiom
annotated source: excretory secretory system morphology variant
annotated property: IAO_0000115
annotated target: Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

obsolete excretory system morphology abnormal
type: Class
IAO_0000115: OBSOLETE.
IAO_0100001: excretory secretory system morphology variant
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000602
deprecated: true

muscle system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005737
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005737
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work.
has narrow synonym: muscle system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000603
in subset: phenotype slim wb

Axiom
annotated source: muscle system morphology variant
annotated property: IAO_0000115
annotated target: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work.
has db xref: GO:0007517
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

nervous system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005735
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005735
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
has narrow synonym: nervous system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: neuroanatomical defective
id: WBPhenotype:0000604
in subset: phenotype slim wb
comment: WB:WBbt:0005735.

Axiom
annotated source: nervous system morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
has db xref: WB:WBPerson712

reproductive system morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005747
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005747
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
has narrow synonym: reproductive system morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000605
in subset: phenotype slim wb

Axiom
annotated source: reproductive system morphology variant
annotated property: IAO_0000115
annotated target: Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

alimentary system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: alimentary system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000606
in subset: phenotype slim wb

Axiom
annotated source: alimentary system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

coelomic system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: coelomic system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000607
in subset: phenotype slim wb

Axiom
annotated source: coelomic system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

epithelial system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: epithelial system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000608
in subset: phenotype slim wb

Axiom
annotated source: epithelial system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

excretory secretory system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: excretory secretory system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000609
in subset: phenotype slim wb

Axiom
annotated source: excretory secretory system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

excretory system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: excretory secretory system physiology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: excretory system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000610
in subset: phenotype slim wb

Axiom
annotated source: excretory system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

muscle system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: muscle system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000611
in subset: phenotype slim wb

Axiom
annotated source: muscle system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

nervous system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: nervous system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000612
in subset: phenotype slim wb

Axiom
annotated source: nervous system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

reproductive system physiology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system physiology phenotype
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0008150
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has narrow synonym: reproductive system physiology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000613
in subset: phenotype slim wb

Axiom
annotated source: reproductive system physiology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
has db xref: GO:0003008
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

GLR development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000942
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has narrow synonym: GLR development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000614

Axiom
annotated source: GLR development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has db xref: WB:WBPerson2021

cilia morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001526
subclass of: WBPhenotype_0002089
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0005929
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.
has narrow synonym: cilia morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: defective dye filling of cilia
id: WBPhenotype:0000615

Axiom
annotated source: cilia morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.
has db xref: WB:WBPaper00000214
has db xref: WB:WBPaper00000932
has db xref: WB:WBPerson712

synapse morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0045202
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: nervous system morphology variant
subclass of: WBPhenotype_0001657
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0045202
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft.
has narrow synonym: synapse morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000616

Axiom
annotated source: synapse morphology variant
annotated property: IAO_0000115
annotated target: Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft.
has db xref: GO:0045202
has db xref: WB:WBPaper00027305
has db xref: WB:WBPerson712

alimentary system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products.
has narrow synonym: alimentary system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000617
in subset: phenotype slim wb

Axiom
annotated source: alimentary system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

coelomic system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control.
has narrow synonym: coelomic system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000618
in subset: phenotype slim wb

Axiom
annotated source: coelomic system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control.
has db xref: WB:WBPerson2021

epithelial system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control.
has narrow synonym: epithelial system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000619
in subset: phenotype slim wb

Axiom
annotated source: epithelial system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control.
has db xref: WB:WBPerson2021

excretory secretory system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands.
has narrow synonym: excretory secretory system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000620
in subset: phenotype slim wb

Axiom
annotated source: excretory secretory system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands.
has db xref: WB:WBPerson2021

excretory system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: excretory secretory system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell.
has narrow synonym: excretory system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000621
in subset: phenotype slim wb

Axiom
annotated source: excretory system development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell.
has db xref: WB:WBPerson2021

muscle system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control.
has narrow synonym: muscle system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000622
in subset: phenotype slim wb

Axiom
annotated source: muscle system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control.
has db xref: WB:WBPerson2021

nervous system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007399
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007399
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control.
has narrow synonym: nervous system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000623
in subset: phenotype slim wb

Axiom
annotated source: nervous system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control.
has db xref: GO:0007399
has db xref: WB:cab

reproductive system development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organ system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control.
has narrow synonym: reproductive system development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: reproductive defect
id: WBPhenotype:0000624
in subset: phenotype slim wb

Axiom
annotated source: reproductive system development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control.
has db xref: WB:WBPerson2021

synaptogenesis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007416
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: nervous system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007416
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the biosynthesis of a synapse compared to control.
has exact synonym: synapse development variant
has narrow synonym: synaptogenesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000625

Axiom
annotated source: synaptogenesis variant
annotated property: IAO_0000115
annotated target: Any variation in the biosynthesis of a synapse compared to control.
has db xref: GO:0007416
has db xref: WB:cab

Axiom
annotated source: synaptogenesis variant
annotated property: hasExactSynonym
annotated target: synapse development variant
has db xref: WB:WBPerson712

habituation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0046959
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: WBPhenotype_0000738
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0046959
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the decrease in a behavioral response to a repeated stimulus compared to control.
has narrow synonym: habituation abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: non associative learning variant
id: WBPhenotype:0000626
in subset: phenotype slim wb

Axiom
annotated source: habituation variant
annotated property: IAO_0000115
annotated target: Any variation in the decrease in a behavioral response to a repeated stimulus compared to control.
has db xref: GO:0046959
has db xref: WB:cab

anesthetic response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0072347
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: drug response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0072347
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.
has exact synonym: anaesthetic response variant
has narrow synonym: anesthetic response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000627

Axiom
annotated source: anesthetic response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.
has db xref: WB:WBPerson557

spindle assembly defective early emb
type: Class
subclass of: WBPhenotype_0001102
subclass of: WBPhenotype_0002415
IAO_0000115: Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
has broad synonym: Emb
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000628
comment: Possible XP.

Axiom
annotated source: spindle assembly defective early emb
annotated property: IAO_0000115
annotated target: Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
has db xref: GO:0051225
has db xref: WB:WBPerson2021
has db xref: WB:cab
has db xref: WB:cgc7141

excess neurite outgrowth
type: Class
subclass of: neuronal outgrowth variant
IAO_0000115: Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000629

Axiom
annotated source: excess neurite outgrowth
annotated property: IAO_0000115
annotated target: Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
has db xref: WB:WBPerson2021

quinine chemotaxis defective
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_15854
subclass of: WBPhenotype_0001449
subclass of: WBPhenotype_0001454
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001511
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050919
    intersection of: Restriction
      on property: in response to
      some values from: CHEBI_15854
IAO_0000115: Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000630

Axiom
annotated source: quinine chemotaxis defective
annotated property: IAO_0000115
annotated target: Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent.
has db xref: WB:WBPaper00006481
has db xref: WB:WBPaper00035961
has db xref: WB:WBPerson712

drug response variant
type: Class
subclass of: chemical response variant
IAO_0000115: Any variation in the characteristic response(s) to drug(s) as defined by control animals.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: drug response abnormal
id: WBPhenotype:0000631

Axiom
annotated source: drug response variant
annotated property: IAO_0000115
annotated target: Any variation in the characteristic response(s) to drug(s) as defined by control animals.
has db xref: WB:cab

axon fasciculation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007413
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000880
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007413
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised.
has narrow synonym: axon fasciculation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000632

Axiom
annotated source: axon fasciculation variant
annotated property: IAO_0000115
annotated target: The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised.
has db xref: GO:0007413
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

axon branching variant
type: Class
subclass of: axon morphology variant
subclass of: WBPhenotype_0001224
IAO_0000115: Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals.
has narrow synonym: axon branching abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000633

Axiom
annotated source: axon branching variant
annotated property: IAO_0000115
annotated target: Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals.
has db xref: GO:0048755
has db xref: WB:WBPaper00027335
has db xref: WB:WBPaper00027711
has db xref: WB:WBPerson712

pharyngeal pumping variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0002056
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0043050
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control.
has narrow synonym: pharyngeal pumping abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000634
in subset: phenotype slim wb

Axiom
annotated source: pharyngeal pumping variant
annotated property: IAO_0000115
annotated target: Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control.
has db xref: GO:0043050
has db xref: WB:cab

positive chemotaxis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001434
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0050918
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals.
has narrow synonym: positive chemotaxis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000635

Axiom
annotated source: positive chemotaxis variant
annotated property: IAO_0000115
annotated target: Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals.
has db xref: GO:0050918
has db xref: WB:cab
has db xref: WB:cgc122
has db xref: WB:cgc387

neuron degeneration variant
type: Class
subclass of: nervous system physiology variant
IAO_0000115: Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.
has narrow synonym: neuron degeneration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000636

Axiom
annotated source: neuron degeneration variant
annotated property: IAO_0000115
annotated target: Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

dauer formation variant
type: Class
subclass of: dauer development phenotype
IAO_0000115: Characteristic entry into the dauer stage is altered compared to control animals.
has broad synonym: Daf
has narrow synonym: dauer formation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000637

Axiom
annotated source: dauer formation variant
annotated property: IAO_0000115
annotated target: Characteristic entry into the dauer stage is altered compared to control animals.
has db xref: WB:cab

molt defect
type: Class
subclass of: WBPhenotype_0002041
IAO_0000115: Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.
has broad synonym: Mlt
has broad synonym: Mult
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000638

Axiom
annotated source: molt defect
annotated property: IAO_0000115
annotated target: Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.
has db xref: GO:0018996
has db xref: WB:WBPerson712

temperature induced dauer formation variant
type: Class
subclass of: organism temperature response variant
subclass of: WBPhenotype_0001539
IAO_0000115: Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.
has narrow synonym: temperature induced dauer formation abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Hid
id: WBPhenotype:0000639

Axiom
annotated source: temperature induced dauer formation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.
has db xref: WB:WBPaper00006103
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:WBPerson712

egg laying variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0018991
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
has broad synonym: Egl
has narrow synonym: egg laying abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: oviposition abnormal
id: WBPhenotype:0000640
in subset: phenotype slim wb
comment: Visual inspection.

Axiom
annotated source: egg laying variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
has db xref: WB:cab
has db xref: pmid:11813735
has db xref: pmid:9697864

Axiom
annotated source: egg laying variant
annotated property: hasRelatedSynonym
annotated target: oviposition abnormal
has db xref: GO:0018991

activity level variant
type: Class
subclass of: locomotion variant
IAO_0000115: Any variation in the degree of movement compared to control animals.
has narrow synonym: activity level abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000641

Axiom
annotated source: activity level variant
annotated property: IAO_0000115
annotated target: Any variation in the degree of movement compared to control animals.
has db xref: WB:cab

hyperactive
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040011
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: activity level variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000912
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040011
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Worms move forward or backward with an increased rate of body bends per minute compared to control animals.
has broad synonym: Hya
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000642

Axiom
annotated source: hyperactive
annotated property: IAO_0000115
annotated target: Worms move forward or backward with an increased rate of body bends per minute compared to control animals.
has db xref: WB:WBPaper00004402
has db xref: WB:WBPaper00006395
has db xref: WB:cab

locomotion variant
type: Class
subclass of: WBPhenotype_0001206
IAO_0000115: Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
has broad synonym: Unc
has narrow synonym: locomotion abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: movement defect
has related synonym: uncoordinated
id: WBPhenotype:0000643
in subset: phenotype slim wb

Axiom
annotated source: locomotion variant
annotated property: IAO_0000115
annotated target: Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
has db xref: GO:0040011
has db xref: WB:WBPaper00024949
has db xref: WB:WBPerson712
has db xref: WB:cab

paralyzed
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000763
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
subclass of: WBPhenotype_0001213
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000763
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
IAO_0000115: Animals do not move and are not responsive to external mechanical stimulation.
has broad synonym: Prl
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Prz
id: WBPhenotype:0000644
in subset: phenotype slim wb

Axiom
annotated source: paralyzed
annotated property: IAO_0000115
annotated target: Animals do not move and are not responsive to external mechanical stimulation.
has db xref: WB:cab

roller
type: Class
subclass of: WBPhenotype_0004017
IAO_0000115: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar.
has broad synonym: Rol
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000645

Axiom
annotated source: roller
annotated property: IAO_0000115
annotated target: The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar.
has db xref: WB:cab
has db xref: WB:cgc31

sluggish
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040011
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001213
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040011
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals move more slowly compared with control animals.
has broad synonym: Slu
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: lethargic
has related synonym: slow
id: WBPhenotype:0000646

Axiom
annotated source: sluggish
annotated property: IAO_0000115
annotated target: Animals move more slowly compared with control animals.
has db xref: WB:cab

copulation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007620
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007620
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another.
has narrow synonym: copulation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000647
in subset: phenotype slim wb

Axiom
annotated source: copulation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another.
has db xref: GO:0007620
has db xref: WB:cab

male mating variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060179
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: copulation variant
subclass of: WBPhenotype_0000888
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060179
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control.
has broad synonym: Cod
has narrow synonym: male mating abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000648

Axiom
annotated source: male mating variant
annotated property: IAO_0000115
annotated target: Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control.
has db xref: GO:0060179
has db xref: WB:cab

vulva location variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034608
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0004006
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0034608
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
has narrow synonym: vulva location abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Lov
id: WBPhenotype:0000649

Axiom
annotated source: vulva location variant
annotated property: IAO_0000115
annotated target: Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
has db xref: GO:0034608
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

defecation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas).
has narrow synonym: defecation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000650
in subset: phenotype slim wb

Axiom
annotated source: defecation variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas).
has db xref: GO:0030421
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557
has db xref: WB:cab

constipated
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
subclass of: defecation variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000502
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030421
IAO_0000115: Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter.
has broad synonym: Con
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000651

Axiom
annotated source: constipated
annotated property: IAO_0000115
annotated target: Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter.
has db xref: WB:WBPerson2021

sensory system variant
type: Class
subclass of: nervous system physiology variant
IAO_0000115: Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
has alternative id: WBPhenotype:0000248
has narrow synonym: sensory system abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000652

Axiom
annotated source: sensory system variant
annotated property: IAO_0000115
annotated target: Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

mechanosensory system variant
type: Class
subclass of: sensory system variant
IAO_0000115: Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
has narrow synonym: mechanosensory system abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000653

Axiom
annotated source: mechanosensory system variant
annotated property: IAO_0000115
annotated target: Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

synaptic vesicle exocytosis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016079
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000728
subclass of: WBPhenotype_0001684
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0016079
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
has narrow synonym: synaptic vesicle exocytosis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000654

Axiom
annotated source: synaptic vesicle exocytosis variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
has db xref: GO:0016079
has db xref: WB:WBPerson712

GABA synaptic transmission variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051932
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: synaptic transmission variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0051932
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
has narrow synonym: GABA synaptic transmission abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000655

Axiom
annotated source: GABA synaptic transmission variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
has db xref: GO:0007268
has db xref: WB:WBPerson712

acetylcholine synaptic transmission variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007271
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: synaptic transmission variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007271
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
has narrow synonym: acetylcholine synaptic transmission abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000656

Axiom
annotated source: acetylcholine synaptic transmission variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
has db xref: GO:0007268
has db xref: WB:WBPerson712

neuronal synaptic transmission variant
type: Class
subclass of: synaptic transmission variant
IAO_0000115: Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas).
has narrow synonym: neuronal synaptic transmission abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000657

Axiom
annotated source: neuronal synaptic transmission variant
annotated property: IAO_0000115
annotated target: Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

neuromuscular synaptic transmission variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007274
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: synaptic transmission variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007274
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals.
has narrow synonym: neuromuscular synaptic transmission abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000658

Axiom
annotated source: neuromuscular synaptic transmission variant
annotated property: IAO_0000115
annotated target: Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

feeding behavior variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007631
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007631
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Behavior associated with the intake of food is altered compared to control.
has narrow synonym: feeding behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000659
in subset: phenotype slim wb

Axiom
annotated source: feeding behavior variant
annotated property: IAO_0000115
annotated target: Behavior associated with the intake of food is altered compared to control.
has db xref: GO:0007631
has db xref: WB:WBPerson557

social feeding increased
type: Class
subclass of: feeding behavior variant
subclass of: WBPhenotype_0001291
IAO_0000115: Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: bordering increased
has related synonym: social behavior enhanced
id: WBPhenotype:0000660

Axiom
annotated source: social feeding increased
annotated property: IAO_0000115
annotated target: Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects.
has db xref: WB:WBPerson712

solitary feeding increased
type: Class
subclass of: feeding behavior variant
subclass of: WBPhenotype_0001291
IAO_0000115: Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: solitary behavior enhanced
has related synonym: solitary forager on food
id: WBPhenotype:0000661

Axiom
annotated source: solitary feeding increased
annotated property: IAO_0000115
annotated target: Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent.
has db xref: WB:WBPaper00003187
has db xref: WB:WBPaper00032342
has db xref: WB:WBPerson712

foraging behavior variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060756
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region.
has broad synonym: Fab
has narrow synonym: foraging behavior abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000662
in subset: phenotype slim wb

Axiom
annotated source: foraging behavior variant
annotated property: IAO_0000115
annotated target: Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region.
has db xref: GO:0060756
has db xref: WB:WBPaper00005621
has db xref: WB:WBPaper00031455
has db xref: WB:WBPerson712

osmotic avoidance variant
type: Class
subclass of: negative chemotaxis variant
IAO_0000115: Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength.
has narrow synonym: osmotic avoidance abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Osm
id: WBPhenotype:0000663

Axiom
annotated source: osmotic avoidance variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength.
has db xref: WB:WBPerson2021

exaggerated body bends
type: Class
subclass of: WBPhenotype_0001703
IAO_0000115: The maximum ventral and dorsal flex of the animal is greater than that observed for control animals.
has alternative id: WBPhenotype:0004021
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: loopy
id: WBPhenotype:0000664

Axiom
annotated source: exaggerated body bends
annotated property: IAO_0000115
annotated target: The maximum ventral and dorsal flex of the animal is greater than that observed for control animals.
has db xref: WB:WBPerson712

connection of gonad variant
type: Class
subclass of: reproductive system morphology variant
IAO_0000115: Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males.
has narrow synonym: connection of gonad abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Cog
id: WBPhenotype:0000665

Axiom
annotated source: connection of gonad variant
annotated property: IAO_0000115
annotated target: Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

ovulation variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030728
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism behavior variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0030728
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
has narrow synonym: ovulation abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000666
in subset: phenotype slim wb

Axiom
annotated source: ovulation variant
annotated property: IAO_0000115
annotated target: Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
has db xref: GO:0030728
has db xref: WB:WBPaper00003017
has db xref: WB:WBPerson2021

gonad displaced
type: Class
subclass of: WBPhenotype_0000977
IAO_0000115: The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: ectopic gonad
id: WBPhenotype:0000667

Axiom
annotated source: gonad displaced
annotated property: IAO_0000115
annotated target: The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

endomitotic oocytes
type: Class
subclass of: WBPhenotype_0001260
IAO_0000115: Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized.
has broad synonym: Emo
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: arrest in meiosis I
id: WBPhenotype:0000668

Axiom
annotated source: endomitotic oocytes
annotated property: IAO_0000115
annotated target: Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized.
has db xref: WB:kmva

sex muscle development variant
type: Class
subclass of: reproductive system development variant
subclass of: WBPhenotype_0000860
IAO_0000115: Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control.
has narrow synonym: sex muscle development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000669

Axiom
annotated source: sex muscle development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

spermatogenesis variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000894
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0007283
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control.
has broad synonym: Spe
has exact synonym: spermatocyte germ cell differentiation abnormal
has narrow synonym: spermatogenesis abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000670

Axiom
annotated source: spermatogenesis variant
annotated property: IAO_0000115
annotated target: Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control.
has db xref: GO:0007283
has db xref: WB:WBPaper00027300
has db xref: WB:WBPerson2021

resistant to copper
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28694
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: copper response variant
subclass of: WBPhenotype_0001502
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001650
    intersection of: Restriction
      on property: RO_0000052
      some values from: CARO_0010004
    intersection of: Restriction
      on property: RO_0002503
      some values from: CHEBI_28694
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000671

Axiom
annotated source: resistant to copper
annotated property: IAO_0000115
annotated target: Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals.
has db xref: WB:WBPerson557

presynaptic vesicle cluster localization variant
type: Class
subclass of: presynaptic vesicle cluster variant
IAO_0000115: Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals.
has narrow synonym: presynaptic vesicle cluster localization abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: synaptic vesicle cluster localization abnormal
id: WBPhenotype:0000672

Axiom
annotated source: presynaptic vesicle cluster localization variant
annotated property: IAO_0000115
annotated target: Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals.
has db xref: WB:WBPaper00027305
has db xref: WB:WBPaper00027711
has db xref: WB:WBPerson712

brood size variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000276
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000806
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000276
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The number of offspring produced is altered compared to that of control animals.
has narrow synonym: brood size abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000673

Axiom
annotated source: brood size variant
annotated property: IAO_0000115
annotated target: The number of offspring produced is altered compared to that of control animals.
has db xref: WB:WBPerson557

slow development
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: general pace of development variant
subclass of: retarded heterochronic variations
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000911
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0032502
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: retarded development
id: WBPhenotype:0000674

Axiom
annotated source: slow development
annotated property: IAO_0000115
annotated target: The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

zygotic lethal
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000365
subclass of: zygotic development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000718
    intersection of: Restriction
      on property: RO_0000052
      some values from: CL_0000365
IAO_0000115: Animals die after fusion of gametes without dividing.
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Emb
id: WBPhenotype:0000675

Axiom
annotated source: zygotic lethal
annotated property: IAO_0000115
annotated target: Animals die after fusion of gametes without dividing.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

growth rate variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001492
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: growth variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001492
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
has narrow synonym: growth rate abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000676

Axiom
annotated source: growth rate variant
annotated property: IAO_0000115
annotated target: The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
has db xref: GO:0040007
has db xref: WB:WBPerson712

chemosensation defective
type: Class
subclass of: WBPhenotype_0001050
IAO_0000115: Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000677

Axiom
annotated source: chemosensation defective
annotated property: IAO_0000115
annotated target: Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals.
has db xref: WB:WBPerson2021

obsolete no copper sensitivity
type: Class
IAO_0000115: OBSOLETE.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000678
comment: This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
deprecated: true

Axiom
annotated source: obsolete no copper sensitivity
annotated property: IAO_0000115
annotated target: OBSOLETE.
has db xref: WB:WBPerson557

transgene subcellular localization variant
type: Class
subclass of: WBPhenotype_0000961
IAO_0000115: Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
has narrow synonym: transgene subcellular localization abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000679

Axiom
annotated source: transgene subcellular localization variant
annotated property: IAO_0000115
annotated target: Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
has db xref: WB:WBPerson557

aldicarb response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001290
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000077
    intersection of: Restriction
      on property: BFO_0000070
      some values from: CHEBI 2555
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response to aldicarb compared to that observed in control animals.
has narrow synonym: aldicarb response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000680

Axiom
annotated source: aldicarb response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to aldicarb compared to that observed in control animals.
has db xref: WB:WBPerson557

DMPP response variant
type: Class
subclass of: drug response variant
IAO_0000115: Animals exhibit variations in their response to DMPP compared to that observed in control animals.
has narrow synonym: DMPP response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000681

Axiom
annotated source: DMPP response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response to DMPP compared to that observed in control animals.
has db xref: WB:WBPerson557

feminization of germline
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000467
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040022
subclass of: feminization of XX and XO animals
subclass of: WBPhenotype_0000812
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000467
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040022
IAO_0000115: Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm.
has broad synonym: Fog
has exact synonym: feminization of germ line
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000682

Axiom
annotated source: feminization of germline
annotated property: IAO_0000115
annotated target: Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm.
has db xref: WB:cab
has db xref: pmid:3396865

masculinization of germline
type: Class
subclass of: WBPhenotype_0000812
subclass of: WBPhenotype_0001572
IAO_0000115: The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm.
has broad synonym: Mog
has exact synonym: masculinization of germ line
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000683

Axiom
annotated source: masculinization of germline
annotated property: IAO_0000115
annotated target: The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm.
has db xref: WB:WBPaper00001710
has db xref: WB:WBPerson2021

fewer germ cells
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001997
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006796
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000823
subclass of: WBPhenotype_0002174
subclass of: WBPhenotype_0002552
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001997
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006796
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Germ cell populations are reduced compared to control animals.
has broad synonym: Fgc
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: germline underproliferation
id: WBPhenotype:0000684

Axiom
annotated source: fewer germ cells
annotated property: IAO_0000115
annotated target: Germ cell populations are reduced compared to control animals.
has db xref: WB:WBPerson2021
has db xref: WB:cab

larval growth slow
type: Class
subclass of: retarded heterochronic variations
subclass of: growth rate variant
subclass of: WBPhenotype_0001016
IAO_0000115: Any variation that causes a reduction in growth rate during larval stages compared to control.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000685

Axiom
annotated source: larval growth slow
annotated property: IAO_0000115
annotated target: Any variation that causes a reduction in growth rate during larval stages compared to control.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

organism ionizing radiation response variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010212
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: organism stress response variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0010212
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in their response ionizing radiation compared to that observed in control animals.
has narrow synonym: organism ionizing radiation response abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000686

Axiom
annotated source: organism ionizing radiation response variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in their response ionizing radiation compared to that observed in control animals.
has db xref: WB:WBPerson557

feminization of XX and XO animals
type: Class
subclass of: postembryonic development variant
subclass of: reproductive system development variant
subclass of: WBPhenotype_0000822
IAO_0000115: Both hermaphrodites and males develop into fertile females.
has broad synonym: Fem
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000687

Axiom
annotated source: feminization of XX and XO animals
annotated property: IAO_0000115
annotated target: Both hermaphrodites and males develop into fertile females.
has db xref: WB:cab

sterile
type: Class
subclass of: WBPhenotype_0001384
IAO_0000115: Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
has broad synonym: Ste
has exact synonym: semi sterile
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000688
in subset: phenotype slim wb

Axiom
annotated source: sterile
annotated property: IAO_0000115
annotated target: Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
has db xref: GO:0000003
has db xref: WB:WBPerson712

maternal sterile
type: Class
subclass of: hermaphrodite sterile
IAO_0000115: Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
has broad synonym: Ste
has exact synonym: Reduced fecundity of injected worm
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: sterile F0 fertility problems
id: WBPhenotype:0000689

Axiom
annotated source: maternal sterile
annotated property: IAO_0000115
annotated target: Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
has db xref: WB:WBPerson557
has db xref: WB:cab
has db xref: WB:cgc5599
has db xref: WB:cgc7141

Axiom
annotated source: maternal sterile
annotated property: hasExactSynonym
annotated target: Reduced fecundity of injected worm
has db xref: WB:cgc5599

gonad migration variant
type: Class
subclass of: reproductive system development variant
IAO_0000115: Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
has broad synonym: Gom
has narrow synonym: gonad migration abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000690

Axiom
annotated source: gonad migration variant
annotated property: IAO_0000115
annotated target: Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

gonad development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008406
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: reproductive system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0008406
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
has narrow synonym: gonad development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: Gon
has related synonym: gonadogenesis abnormal
id: WBPhenotype:0000691

Axiom
annotated source: gonad development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
has db xref: GO:0008406
has db xref: WB:WBPerson2021

male sterile
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000956
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000056
subclass of: sterile
subclass of: WBPhenotype_0000863
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000956
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007833
    intersection of: Restriction
      on property: during
      some values from: WBls_0000056
IAO_0000115: X0 animals fail to generate viable cross-progeny.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000692

Axiom
annotated source: male sterile
annotated property: IAO_0000115
annotated target: X0 animals fail to generate viable cross-progeny.
has db xref: WB:WBPerson2021

male sperm fertilization defect
type: Class
subclass of: male sterile
IAO_0000115: Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte.
has broad synonym: Fer
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000693

Axiom
annotated source: male sperm fertilization defect
annotated property: IAO_0000115
annotated target: Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte.
has db xref: WB:WBPaper00001075
has db xref: WB:WBPerson2021

hermaphrodite sterile
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000956
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007849
subclass of: sterile
subclass of: WBPhenotype_0001259
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000956
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0007849
IAO_0000115: Hermaphrodites fail to generate viable self-progeny and/or cross-progeny.
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000694

Axiom
annotated source: hermaphrodite sterile
annotated property: IAO_0000115
annotated target: Hermaphrodites fail to generate viable self-progeny and/or cross-progeny.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

vulva morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0001335
subclass of: WBPhenotype_0002553
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control.
has narrow synonym: vulva morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000695

Axiom
annotated source: vulva morphology variant
annotated property: IAO_0000115
annotated target: Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control.
has db xref: WB:WBPerson712

everted vulva
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001597
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
subclass of: vulva morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001597
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
IAO_0000115: The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
has broad synonym: Evl
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000696

Axiom
annotated source: everted vulva
annotated property: IAO_0000115
annotated target: The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
has db xref: WB:WBPaper00001738
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson261
has db xref: WB:cab

protruding vulva
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
subclass of: vulva morphology variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001598
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
IAO_0000115: Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
has broad synonym: Pvl
has broad synonym: Pvu
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000697

Axiom
annotated source: protruding vulva
annotated property: IAO_0000115
annotated target: Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
has db xref: WB:WBPaper00004408
has db xref: WB:WBPerson2021

vulvaless
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: vulval cell induction reduced
subclass of: WBPhenotype_0002553
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000462
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate.
has broad synonym: Vul
has exact synonym: underinduced
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000698
in subset: phenotype slim wb

Axiom
annotated source: vulvaless
annotated property: IAO_0000115
annotated target: No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate.
has db xref: WB:WBPaper00001182
has db xref: WB:WBPerson2021

vulva development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040025
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: reproductive system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0040025
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
has narrow synonym: vulva development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000699
in subset: phenotype slim wb

Axiom
annotated source: vulva development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
has db xref: GO:0040025
has db xref: WB:IA
has db xref: WB:WBPerson2021

multivulva
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: vulval cell induction increased
subclass of: WBPhenotype_0002553
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000470
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0006748
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates.
has broad synonym: Muv
has exact synonym: overinduced
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000700

Axiom
annotated source: multivulva
annotated property: IAO_0000115
annotated target: Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates.
has db xref: WB:WBPaper00001182
has db xref: WB:WBPerson2021

epithelial development variant
type: Class
subclass of: epithelial system development variant
IAO_0000115: Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation.
has narrow synonym: epithelial development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: epidermal morphogenesis variant
id: WBPhenotype:0000701

Axiom
annotated source: epithelial development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation.
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

epithelial cell fusion failure
type: Class
subclass of: cell fusion variant
subclass of: epithelial development variant
IAO_0000115: Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
has db xref: PMID:15341747
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000702

Axiom
annotated source: epithelial cell fusion failure
annotated property: IAO_0000115
annotated target: Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
has db xref: WB:WBPaper00005122
has db xref: WB:WBPerson2021

epithelial morphology variant
type: Class
subclass of: epithelial system morphology variant
IAO_0000115: Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas).
has narrow synonym: epithelial morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: hypodermal morphology abnormal
id: WBPhenotype:0000703

Axiom
annotated source: epithelial morphology variant
annotated property: IAO_0000115
annotated target: Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

excretory canal morphology variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: WBPhenotype_0000916
subclass of: WBPhenotype_0002558
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0000051
    intersection of: Restriction
      on property: RO_0000052
      some values from: WBbt_0005775
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas).
has narrow synonym: excretory canal morphology abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000704

Axiom
annotated source: excretory canal morphology variant
annotated property: IAO_0000115
annotated target: Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas).
has db xref: WB:WBPerson2021
has db xref: WB:WBPerson557

intestinal cell development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: cell development variant
subclass of: intestinal development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: Class
        intersection of: GO_0032502
        intersection of: Restriction
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has narrow synonym: intestinal cell development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000705

Axiom
annotated source: intestinal cell development variant
annotated property: IAO_0000115
annotated target: Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
has db xref: WB:WBPerson2021

gut granule biogenesis reduced
type: Class
subclass of: gut granule development variant
subclass of: WBPhenotype_0001430
IAO_0000115: Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages.
has broad synonym: Glo
has db xref: PMID:15843430
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: gut granule loss
id: WBPhenotype:0000706

Axiom
annotated source: gut granule biogenesis reduced
annotated property: IAO_0000115
annotated target: Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages.
has db xref: WB:WBPaper00032168
has db xref: WB:WBPerson712

pharyngeal development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060465
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0060465
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb).
has narrow synonym: pharyngeal development abnormal
has OBO namespace: C_elegans_phenotype_ontology
id: WBPhenotype:0000707

Axiom
annotated source: pharyngeal development variant
annotated property: IAO_0000115
annotated target: Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb).
has db xref: GO:0043282
has db xref: WB:WBPerson2021

intestinal development variant
type: Class
equivalent class: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048565
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
subclass of: alimentary system development variant
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: PATO_0001236
    intersection of: Restriction
      on property: RO_0000052
      some values from: GO_0048565
    intersection of: Restriction
      on property: RO_0002573
      some values from: PATO_0000460
IAO_0000115: Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control.
has narrow synonym: intestinal development abnormal
has OBO namespace: C_elegans_phenotype_ontology
has related synonym: endoderm development abnormal
has related synonym: gut development abnormal
id: WBPhenotype:0000708