Prefix(:=<http://purl.obolibrary.org/obo/cl.owl#>)
Prefix(cl:=<http://purl.obolibrary.org/obo/cl#>)
Prefix(dc:=<http://purl.org/dc/elements/1.1/>)
Prefix(go:=<http://purl.obolibrary.org/obo/go#>)
Prefix(pr:=<http://purl.obolibrary.org/obo/pr#>)
Prefix(obo:=<http://purl.obolibrary.org/obo/>)
Prefix(owl:=<http://www.w3.org/2002/07/owl#>)
Prefix(rdf:=<http://www.w3.org/1999/02/22-rdf-syntax-ns#>)
Prefix(xml:=<http://www.w3.org/XML/1998/namespace>)
Prefix(xsd:=<http://www.w3.org/2001/XMLSchema#>)
Prefix(core:=<http://purl.obolibrary.org/obo/uberon/core#>)
Prefix(foaf:=<http://xmlns.com/foaf/0.1/>)
Prefix(pato:=<http://purl.obolibrary.org/obo/pato#>)
Prefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)
Prefix(sssom:=<https://w3id.org/sssom/>)
Prefix(terms:=<http://purl.org/dc/terms/>)
Prefix(uberon:=<http://purl.obolibrary.org/obo/uberon#>)
Prefix(ubprop:=<http://purl.obolibrary.org/obo/ubprop#>)
Prefix(subsets:=<http://purl.obolibrary.org/obo/ro/subsets#>)
Prefix(oboInOwl:=<http://www.geneontology.org/formats/oboInOwl#>)
Prefix(ncbitaxon:=<http://purl.obolibrary.org/obo/ncbitaxon#>)


Ontology(<http://purl.obolibrary.org/obo/cl.owl>
Import(<http://purl.obolibrary.org/obo/cl/components/PNS_neurons.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/bgo-cl-comp.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/blood_and_immune_upper_slim.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/cellxgene_subset.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/clm-cl.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/eye_upper_slim.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/general_cell_types_upper_slim.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/hra_subset.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/kidney_upper_slim.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/mappings.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/wmbo-cl-comp.owl>)
Import(<http://purl.obolibrary.org/obo/cl/components/2DFTU_HRA_illustrations.owl>)
Import(<http://purl.obolibrary.org/obo/cl/imports/merged_import.owl>)
Import(<http://purl.obolibrary.org/obo/cl/patterns/definitions.owl>)
Annotation(obo:IAO_0000700 obo:CL_0000000)
Annotation(dc:description "An ontology of cell types.")
Annotation(dc:title "Cell Ontology")
Annotation(terms:contributor <https://orcid.org/0000-0001-5208-3432>)
Annotation(terms:contributor <https://orcid.org/0000-0001-9114-8737>)
Annotation(terms:contributor <https://orcid.org/0000-0001-9990-8331>)
Annotation(terms:contributor <https://orcid.org/0000-0002-2244-7917>)
Annotation(terms:contributor <https://orcid.org/0000-0002-6601-2165>)
Annotation(terms:contributor <https://orcid.org/0000-0002-7073-9172>)
Annotation(terms:contributor <https://orcid.org/0000-0002-8688-6599>)
Annotation(terms:contributor <https://orcid.org/0000-0002-9900-7880>)
Annotation(terms:contributor <https://orcid.org/0000-0003-1980-3228>)
Annotation(terms:license <http://creativecommons.org/licenses/by/4.0/>)
Annotation(rdfs:comment "See PMID:15693950, PMID:12799354, PMID:20123131, PMID:21208450; Contact Alexander Diehl, addiehl[at]buffalo.edu, university at buffalo.")

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Declaration(AnnotationProperty(oboInOwl:SynonymTypeProperty))
Declaration(AnnotationProperty(oboInOwl:consider))
Declaration(AnnotationProperty(oboInOwl:creation_date))
Declaration(AnnotationProperty(oboInOwl:hasBroadSynonym))
Declaration(AnnotationProperty(oboInOwl:hasDbXref))
Declaration(AnnotationProperty(oboInOwl:hasExactSynonym))
Declaration(AnnotationProperty(oboInOwl:hasNarrowSynonym))
Declaration(AnnotationProperty(oboInOwl:hasRelatedSynonym))
Declaration(AnnotationProperty(oboInOwl:hasSynonymType))
Declaration(AnnotationProperty(oboInOwl:id))
Declaration(AnnotationProperty(oboInOwl:inSubset))
Declaration(AnnotationProperty(oboInOwl:is_inferred))
Declaration(AnnotationProperty(oboInOwl:shorthand))
Declaration(AnnotationProperty(rdfs:comment))
Declaration(AnnotationProperty(rdfs:label))
Declaration(AnnotationProperty(rdfs:seeAlso))
Declaration(AnnotationProperty(owl:deprecated))
############################
#   Annotation Properties
############################

# Annotation Property: obo:IAO_0000028 (symbol)

AnnotationAssertion(rdfs:label obo:IAO_0000028 "symbol")

# Annotation Property: cl:BDS_subset (cl:BDS_subset)

SubAnnotationPropertyOf(cl:BDS_subset oboInOwl:SubsetProperty)

# Annotation Property: cl:added_for_HCA (cl:added_for_HCA)

SubAnnotationPropertyOf(cl:added_for_HCA oboInOwl:SubsetProperty)

# Annotation Property: cl:blood_and_immune_upper_slim (blood_and_immune_upper_slim)

AnnotationAssertion(terms:date cl:blood_and_immune_upper_slim "2023-03-31T09:17:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment cl:blood_and_immune_upper_slim "a subset of general classes related to blood and the immune system, primarily of hematopoietic origin")
AnnotationAssertion(rdfs:label cl:blood_and_immune_upper_slim "blood_and_immune_upper_slim")
SubAnnotationPropertyOf(cl:blood_and_immune_upper_slim oboInOwl:SubsetProperty)

# Annotation Property: cl:eye_upper_slim (eye_upper_slim)

AnnotationAssertion(rdfs:comment cl:eye_upper_slim "a subset of general classes related to specific cell types in the eye.")
AnnotationAssertion(rdfs:label cl:eye_upper_slim "eye_upper_slim")
SubAnnotationPropertyOf(cl:eye_upper_slim oboInOwl:SubsetProperty)

# Annotation Property: cl:general_cell_types_upper_slim (general_cell_types_upper_slim)

AnnotationAssertion(rdfs:comment cl:general_cell_types_upper_slim "a subset of general classes of cell types in the cell ontology.")
AnnotationAssertion(rdfs:label cl:general_cell_types_upper_slim "general_cell_types_upper_slim")
SubAnnotationPropertyOf(cl:general_cell_types_upper_slim oboInOwl:SubsetProperty)

# Annotation Property: cl:kidney_upper_slim (kidney_upper_slim)

AnnotationAssertion(terms:date cl:kidney_upper_slim "2023-11-22T11:18:57Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment cl:kidney_upper_slim "a subset of general classes related to specific cell types in the kidney")
AnnotationAssertion(rdfs:label cl:kidney_upper_slim "kidney_upper_slim")
SubAnnotationPropertyOf(cl:kidney_upper_slim oboInOwl:SubsetProperty)

# Annotation Property: pato:location_grouping (pato:location_grouping)

SubAnnotationPropertyOf(pato:location_grouping oboInOwl:SubsetProperty)

# Annotation Property: uberon:HUMAN_PREFERRED (preferred term when talking about an instance of this class in Homo sapiens)

AnnotationAssertion(rdfs:label uberon:HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens")
SubAnnotationPropertyOf(uberon:HUMAN_PREFERRED oboInOwl:SynonymTypeProperty)

# Annotation Property: uberon:LATIN (latin term)

AnnotationAssertion(rdfs:label uberon:LATIN "latin term")
SubAnnotationPropertyOf(uberon:LATIN oboInOwl:SynonymTypeProperty)

# Annotation Property: uberon:PLURAL (plural term)

AnnotationAssertion(rdfs:label uberon:PLURAL "plural term")
SubAnnotationPropertyOf(uberon:PLURAL oboInOwl:SynonymTypeProperty)

# Annotation Property: core:human_reference_atlas (core:human_reference_atlas)

SubAnnotationPropertyOf(core:human_reference_atlas oboInOwl:SubsetProperty)

# Annotation Property: ubprop:_upper_level (ubprop:_upper_level)

AnnotationAssertion(rdfs:comment ubprop:_upper_level "abstract upper-level terms not directly useful for analysis")
SubAnnotationPropertyOf(ubprop:_upper_level oboInOwl:SubsetProperty)

# Annotation Property: oboInOwl:SubsetProperty (subset_property)

AnnotationAssertion(rdfs:label oboInOwl:SubsetProperty "subset_property")

# Annotation Property: oboInOwl:consider (consider)

AnnotationAssertion(rdfs:label oboInOwl:consider "consider")

# Annotation Property: oboInOwl:inSubset (in_subset)

AnnotationAssertion(rdfs:label oboInOwl:inSubset "in_subset")

# Annotation Property: rdfs:seeAlso (see also)

AnnotationAssertion(oboInOwl:hasDbXref rdfs:seeAlso "http://www.w3.org/2000/01/rdf-schema#seeAlso")
AnnotationAssertion(oboInOwl:shorthand rdfs:seeAlso "seeAlso")
AnnotationAssertion(rdfs:label rdfs:seeAlso "see also")


############################
#   Object Properties
############################

# Object Property: obo:CL_4030044 (has_not_completed)

AnnotationAssertion(rdfs:label obo:CL_4030044 "has_not_completed")

# Object Property: obo:CL_4030045 (lacks_part)

AnnotationAssertion(obo:IAO_0000424 obo:CL_4030045 "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y")
AnnotationAssertion(rdfs:label obo:CL_4030045 "lacks_part")

# Object Property: obo:CL_4030046 (lacks_plasma_membrane_part)

AnnotationAssertion(obo:IAO_0000424 obo:CL_4030046 "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)")
AnnotationAssertion(rdfs:label obo:CL_4030046 "lacks_plasma_membrane_part")

# Object Property: cl:has_high_plasma_membrane_amount (obsolete has_high_plasma_membrane_amount)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19243617") obo:IAO_0000115 cl:has_high_plasma_membrane_amount "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).")
AnnotationAssertion(obo:IAO_0000233 cl:has_high_plasma_membrane_amount <https://github.com/obophenotype/cell-ontology/issues/1481>)
AnnotationAssertion(obo:IAO_0100001 cl:has_high_plasma_membrane_amount obo:RO_0015015)
AnnotationAssertion(rdfs:label cl:has_high_plasma_membrane_amount "obsolete has_high_plasma_membrane_amount")
AnnotationAssertion(owl:deprecated cl:has_high_plasma_membrane_amount "true"^^xsd:boolean)

# Object Property: cl:has_low_plasma_membrane_amount (obsolete has_low_plasma_membrane_amount)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19243617") obo:IAO_0000115 cl:has_low_plasma_membrane_amount "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).")
AnnotationAssertion(obo:IAO_0000233 cl:has_low_plasma_membrane_amount <https://github.com/obophenotype/cell-ontology/issues/1481>)
AnnotationAssertion(obo:IAO_0100001 cl:has_low_plasma_membrane_amount obo:RO_0015016)
AnnotationAssertion(rdfs:label cl:has_low_plasma_membrane_amount "obsolete has_low_plasma_membrane_amount")
AnnotationAssertion(owl:deprecated cl:has_low_plasma_membrane_amount "true"^^xsd:boolean)



############################
#   Classes
############################

# Class: obo:CL_0000000 (cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CARO:mah") obo:IAO_0000115 obo:CL_0000000 "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "CALOHA:TS-2035")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "FMA:68646")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "GO:0005623")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "KUPO:0000002")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "MESH:D002477")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "VHOG:0001533")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "WBbt:0004017")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000000 "XAO:0003012")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000000 ubprop:_upper_level)
AnnotationAssertion(rdfs:comment obo:CL_0000000 "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).")
AnnotationAssertion(rdfs:label obo:CL_0000000 "cell")
SubClassOf(obo:CL_0000000 obo:UBERON_0000061)
SubClassOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_131567))

# Class: obo:CL_0000001 (primary cultured cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0000001 "A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000001 "BTO:0002290")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000001 "primary cell culture cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000001 "unpassaged cultured cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000001 "primary cell line cell")
AnnotationAssertion(rdfs:comment obo:CL_0000001 "Covers cells actively being cultured or stored in a quiescent state for future use.")
AnnotationAssertion(rdfs:label obo:CL_0000001 "primary cultured cell")
SubClassOf(obo:CL_0000001 obo:CL_0000010)

# Class: obo:CL_0000002 (obsolete immortal cell line cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0000002 "OBSOLETE: A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite growth/propagation in vitro as part of a immortal cell line.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000002 obo:CLO_0000019)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000002 "continuous cell line cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000002 "permanent cell line cell")
AnnotationAssertion(rdfs:comment obo:CL_0000002 "Obsoleted in July 2013 and replaced by the CLO 'immortal cell line cell' class, as a result of CLO-OBI-CL alignment efforts.

Covers cells actively being cultured or stored in a quiescent state for future use.")
AnnotationAssertion(rdfs:label obo:CL_0000002 "obsolete immortal cell line cell")
AnnotationAssertion(owl:deprecated obo:CL_0000002 "true"^^xsd:boolean)

# Class: obo:CL_0000003 (obsolete native cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CARO:mah") obo:IAO_0000115 obo:CL_0000003 "OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000003 <https://github.com/obophenotype/cell-ontology/issues/2124>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000003 obo:CL_0000000)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000003 "CARO:0000013")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000003 "cell in vivo")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000003 ubprop:_upper_level)
AnnotationAssertion(rdfs:label obo:CL_0000003 "obsolete native cell")
AnnotationAssertion(owl:deprecated obo:CL_0000003 "true"^^xsd:boolean)

# Class: obo:CL_0000004 (obsolete cell by organism)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000004 "OBSOLETE: A classification of cells by the organisms within which they are contained.")
AnnotationAssertion(oboInOwl:consider obo:CL_0000004 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000004 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000004 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000004 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its species. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000004 "obsolete cell by organism")
AnnotationAssertion(owl:deprecated obo:CL_0000004 "true"^^xsd:boolean)

# Class: obo:CL_0000005 (neural crest derived fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000005 "Any fibroblast that is derived from the neural crest.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000005 "fibroblast neural crest derived")
AnnotationAssertion(rdfs:label obo:CL_0000005 "neural crest derived fibroblast")
EquivalentClasses(obo:CL_0000005 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)))
SubClassOf(obo:CL_0000005 obo:CL_0000057)
SubClassOf(obo:CL_0000005 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000006 (neuronal receptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000006 "neuronal receptor cell (sensu Animalia)")
AnnotationAssertion(rdfs:label obo:CL_0000006 "neuronal receptor cell")
EquivalentClasses(obo:CL_0000006 ObjectIntersectionOf(obo:CL_0000197 obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))
SubClassOf(obo:CL_0000006 obo:CL_0000197)

# Class: obo:CL_0000007 (early embryonic cell (metazoa))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000007 "A cell found in the embryo before the formation of all the gem layers is complete.")
AnnotationAssertion(rdfs:label obo:CL_0000007 "early embryonic cell (metazoa)")
SubClassOf(obo:CL_0000007 obo:CL_0002321)

# Class: obo:CL_0000008 (migratory cranial neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0007091") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000008 "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.")
AnnotationAssertion(rdfs:label obo:CL_0000008 "migratory cranial neural crest cell")
SubClassOf(obo:CL_0000008 obo:CL_0000333)

# Class: obo:CL_0000009 (obsolete fusiform initial)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000009 "Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000009 obo:PO_0000079)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000009 "xylem initial")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000009 "xylem mother cell")
AnnotationAssertion(rdfs:label obo:CL_0000009 "obsolete fusiform initial")
AnnotationAssertion(owl:deprecated obo:CL_0000009 "true"^^xsd:boolean)

# Class: obo:CL_0000010 (cultured cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0000010 "A cell in vitro that is or has been maintained or propagated as part of a cell culture.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000010 "MESH:D002478")
AnnotationAssertion(rdfs:comment obo:CL_0000010 "Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture.")
AnnotationAssertion(rdfs:label obo:CL_0000010 "cultured cell")
SubClassOf(obo:CL_0000010 obo:CL_0000578)

# Class: obo:CL_0000011 (migratory trunk neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0007095") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000011 "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.")
AnnotationAssertion(rdfs:label obo:CL_0000011 "migratory trunk neural crest cell")
SubClassOf(obo:CL_0000011 obo:CL_0000333)

# Class: obo:CL_0000012 (obsolete cell by class)

AnnotationAssertion(oboInOwl:consider obo:CL_0000012 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000012 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000012 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000012 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000012 "obsolete cell by class")
AnnotationAssertion(owl:deprecated obo:CL_0000012 "true"^^xsd:boolean)

# Class: obo:CL_0000013 (obsolete dentine secreting cell)

AnnotationAssertion(oboInOwl:consider obo:CL_0000013 "CL:0000140")
AnnotationAssertion(rdfs:label obo:CL_0000013 "obsolete dentine secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000013 "true"^^xsd:boolean)

# Class: obo:CL_0000014 (germ line stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2012.05.016") obo:IAO_0000115 obo:CL_0000014 "A stem cell that is the precursor of gametes.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000014 "germline stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000014 "germ line stem cell")
EquivalentClasses(obo:CL_0000014 ObjectIntersectionOf(obo:CL_0000039 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000014 obo:CL_0000034)

# Class: obo:CL_0000015 (male germ cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29462262") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000015 "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "FMA:72290")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "MA:0002765")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "VHOG:0001531")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "ncithesaurus:Spermatogenic_Cell")
AnnotationAssertion(rdfs:label obo:CL_0000015 "male germ cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0000015 "https://github.com/obophenotype/cell-ontology/issues/574")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000015 obo:CL_0000586)
SubClassOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0007283))

# Class: obo:CL_0000016 (male germ line stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2012.05.016") obo:IAO_0000115 obo:CL_0000016 "A stem cell that is the precursor of male gametes.")
AnnotationAssertion(rdfs:label obo:CL_0000016 "male germ line stem cell")
SubClassOf(obo:CL_0000016 obo:CL_0000014)
SubClassOf(obo:CL_0000016 obo:CL_0000015)

# Class: obo:CL_0000017 (spermatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D013090") obo:IAO_0000115 obo:CL_0000017 "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000017 "BTO:0001275")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000017 "CALOHA:TS-0951")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000017 "EMAPA:31484")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000017 "FMA:84049")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000017 "WBbt:0006799")
AnnotationAssertion(rdfs:label obo:CL_0000017 "spermatocyte")
EquivalentClasses(obo:CL_0000017 ObjectIntersectionOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048137)))
SubClassOf(obo:CL_0000017 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000020))

# Class: obo:CL_0000018 (spermatid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013087") obo:IAO_0000115 obo:CL_0000018 "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000018 "BTO:0001274")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000018 "CALOHA:TS-0950")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000018 "EMAPA:31486")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000018 "FMA:72294")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000018 "WBbt:0006800")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000018 "nematoblast")
AnnotationAssertion(rdfs:label obo:CL_0000018 "spermatid")
EquivalentClasses(obo:CL_0000018 ObjectIntersectionOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001675) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007288) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007289)))
SubClassOf(obo:CL_0000018 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000657))

# Class: obo:CL_0000019 (sperm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D013094") obo:IAO_0000115 obo:CL_0000019 "A mature male germ cell that develops from a spermatid.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000019 "BTO:0001277")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000019 "BTO:0002046")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000019 "CALOHA:TS-0949")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000019 "FMA:67338")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000019 "WBbt:0006798")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "sperm cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "spermatozoid")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "spermatozoon")
AnnotationAssertion(rdfs:label obo:CL_0000019 "sperm")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000019 obo:CL_0000408)
SubClassOf(obo:CL_0000019 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000018))

# Class: obo:CL_0000020 (spermatogonium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013093") obo:IAO_0000115 obo:CL_0000020 "An euploid male germ cell of an early stage of spermatogenesis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000020 "BTO:0000958")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000020 "CALOHA:TS-2193")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000020 "EMAPA:31482")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000020 "FMA:72291")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000020 "spermatogonial cell")
AnnotationAssertion(rdfs:label obo:CL_0000020 "spermatogonium")
EquivalentClasses(obo:CL_0000020 ObjectIntersectionOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001394) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501)))

# Class: obo:CL_0000021 (female germ cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11023867") Annotation(oboInOwl:hasDbXref "PMID:20454446") obo:IAO_0000115 obo:CL_0000021 "Female germ cell is a germ cell that supports female gamete production.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000021 "MA:0000388")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000021 "VHOG:0001530")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000021 "ncithesaurus:Egg")
AnnotationAssertion(rdfs:label obo:CL_0000021 "female germ cell")
EquivalentClasses(obo:CL_0000021 ObjectIntersectionOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048477)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000021 obo:CL_0000586)

# Class: obo:CL_0000022 (female germ line stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2012.05.016") obo:IAO_0000115 obo:CL_0000022 "A stem cell that is the precursor of female gametes.")
AnnotationAssertion(rdfs:label obo:CL_0000022 "female germ line stem cell")
EquivalentClasses(obo:CL_0000022 ObjectIntersectionOf(obo:CL_0000021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000022 obo:CL_0000014)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000022 obo:CL_0000021)

# Class: obo:CL_0000023 (oocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000023 "A female germ cell that has entered meiosis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "BTO:0000964")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "CALOHA:TS-0711")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "FMA:18644")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "MESH:D009865")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "WBbt:0006797")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000023 "oogonium")
AnnotationAssertion(rdfs:label obo:CL_0000023 "oocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000023 obo:CL_0000021)
SubClassOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0007143))
SubClassOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33208))

# Class: obo:CL_0000024 (oogonial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000024 "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000024 "FMA:83673")
AnnotationAssertion(rdfs:label obo:CL_0000024 "oogonial cell")
EquivalentClasses(obo:CL_0000024 ObjectIntersectionOf(obo:CL_0000021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0000278)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000024 obo:CL_0000021)
SubClassOf(obo:CL_0000024 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000670))

# Class: obo:CL_0000025 (egg cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000025 "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000025 "BTO:0000369")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000025 "BTO:0003801")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000025 "CALOHA:TS-2191")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000025 "FMA:67343")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000025 "MESH:D010063")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000025 "mature oocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000025 "ovum")
AnnotationAssertion(rdfs:label obo:CL_0000025 "egg cell")
AnnotationAssertion(foaf:depiction obo:CL_0000025 "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000025 obo:CL_0000675)
SubClassOf(obo:CL_0000025 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0007143))
SubClassOf(obo:CL_0000025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000023))

# Class: obo:CL_0000026 (invertebrate nurse cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15848391") obo:IAO_0000115 obo:CL_0000026 "A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000026 "BTO:0000953")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000026 "nurse cell")
AnnotationAssertion(rdfs:label obo:CL_0000026 "invertebrate nurse cell")
SubClassOf(obo:CL_0000026 obo:CL_0000412)
SubClassOf(obo:CL_0000026 obo:CL_4029002)
SubClassOf(obo:CL_0000026 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000722))

# Class: obo:CL_0000027 (smooth muscle cell neural crest derived)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000027 "A smooth muscle cell derived from the neural crest.")
AnnotationAssertion(rdfs:label obo:CL_0000027 "smooth muscle cell neural crest derived")
EquivalentClasses(obo:CL_0000027 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000027 obo:CL_0000192)
SubClassOf(obo:CL_0000027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000028 (CNS neuron (sensu Nematoda and Protostomia))

AnnotationAssertion(rdfs:label obo:CL_0000028 "CNS neuron (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000028 obo:CL_2000029)
SubClassOf(obo:CL_0000028 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_0000028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000338))

# Class: obo:CL_0000029 (neural crest derived neuron)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000029 "neuron neural crest derived")
AnnotationAssertion(rdfs:label obo:CL_0000029 "neural crest derived neuron")
EquivalentClasses(obo:CL_0000029 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000029 obo:CL_0000540)
SubClassOf(obo:CL_0000029 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002676))

# Class: obo:CL_0000030 (glioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824650") Annotation(oboInOwl:hasDbXref "Wikipedia:Glioblast") obo:IAO_0000115 obo:CL_0000030 "A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000030 "glioblast")
SubClassOf(obo:CL_0000030 obo:CL_0011026)
SubClassOf(obo:CL_0000030 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0000031 (neuroblast (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Neuroblast") obo:IAO_0000115 obo:CL_0000031 "A cell that will develop into a neuron often after a migration phase.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000031 "BTO:0000930")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000031 "FMA:70563")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000031 "neuroblast")
AnnotationAssertion(rdfs:label obo:CL_0000031 "neuroblast (sensu Vertebrata)")
SubClassOf(obo:CL_0000031 obo:CL_0011026)
SubClassOf(obo:CL_0000031 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000032 (neuroplacodal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000032 "A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000032 "neural placode cell")
AnnotationAssertion(rdfs:label obo:CL_0000032 "neuroplacodal cell")
SubClassOf(obo:CL_0000032 obo:CL_0002321)
SubClassOf(obo:CL_0000032 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000114))

# Class: obo:CL_0000033 (apocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "PMID:25960390") obo:IAO_0000115 obo:CL_0000033 "An exocrine cell characterized by loss of part of the cytoplasm during the process of secretion. The secreted substance is accumulated at the apical end and is either budded off through the plasma membrane producing secreted vesicles or dissolved in the cytoplasm that is lost during secretion.")
AnnotationAssertion(rdfs:label obo:CL_0000033 "apocrine cell")
SubClassOf(obo:CL_0000033 obo:CL_0000152)

# Class: obo:CL_0000034 (stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D013234") obo:IAO_0000115 obo:CL_0000034 "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000034 "CALOHA:TS-2086")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000034 "FMA:63368")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000034 "animal stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0000034 "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.")
AnnotationAssertion(rdfs:label obo:CL_0000034 "stem cell")
EquivalentClasses(obo:CL_0000034 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))
SubClassOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33208))
SubClassOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030154))

# Class: obo:CL_0000035 (single fate stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000035 "A stem cell that self-renews as well as give rise to a single mature cell type.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000035 "FMA:70569")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000035 "unipotent stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000035 "unipotential stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000035 "single fate stem cell")
EquivalentClasses(obo:CL_0000035 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001400) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))
SubClassOf(obo:CL_0000035 obo:CL_0000723)

# Class: obo:CL_0000036 (epithelial fate stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17289566") Annotation(oboInOwl:hasDbXref "doi:/10.1038/sj.eye.6700575") obo:IAO_0000115 obo:CL_0000036 "A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000036 "epithelial stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000036 "epithelial fate stem cell")
EquivalentClasses(obo:CL_0000036 ObjectIntersectionOf(obo:CL_0000723 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030855)))

# Class: obo:CL_0000037 (hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell") obo:IAO_0000115 obo:CL_0000037 "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000037 "BTO:0000725")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000037 "CALOHA:TS-0448")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000037 "FMA:86475")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000037 "MESH:D006412")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000037 "VHOG:0001485")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000037 "blood forming stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000037 "hemopoietic stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000037 "HSC")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000037 "colony forming unit hematopoietic")
AnnotationAssertion(rdfs:comment obo:CL_0000037 "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000037 "hematopoietic stem cell")
EquivalentClasses(obo:CL_0000037 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002244) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048103)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000037 obo:CL_0000988)
SubClassOf(obo:CL_0000037 obo:CL_0008001)
SubClassOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000566))

# Class: obo:CL_0000038 (erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000038 "A progenitor cell committed to the erythroid lineage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000038 "BTO:0004911")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000038 "BFU-E")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000038 "CFU-E")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "blast forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "burst forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "colony forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "erythroid stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000038 "erythroid progenitor cell")
SubClassOf(obo:CL_0000038 obo:CL_0000764)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000038 obo:CL_0000839)
SubClassOf(obo:CL_0000038 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050))

# Class: obo:CL_0000039 (germ line cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000039 "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000039 ubprop:_upper_level)
AnnotationAssertion(rdfs:comment obo:CL_0000039 "Originally this term had some plant germ line cell children.")
AnnotationAssertion(rdfs:label obo:CL_0000039 "germ line cell")
SubClassOf(obo:CL_0000039 obo:CL_0000000)
SubClassOf(obo:CL_0000039 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0022414))

# Class: obo:CL_0000040 (monoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:1104740") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Monoblast") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0000040 "A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000040 "CALOHA:TS-1195")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000040 "FMA:83553")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000040 "CFU-M")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000040 "colony forming unit macrophage")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000040 "colony forming unit monocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000040 "monocyte stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0000040 "Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000040 "monoblast")
EquivalentClasses(obo:CL_0000040 ObjectIntersectionOf(obo:CL_0002194 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000791) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005730) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000040 obo:CL_0002194)
SubClassOf(obo:CL_0000040 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002009))

# Class: obo:CL_0000041 (mature eosinophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000041 "A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive.")
AnnotationAssertion(obo:IAO_0000116 obo:CL_0000041 "The status of eosinophils as true professional antigen presenting cells is unclear, despite their ability to present exogenous peptides and peptides processed from exogenous proteins (in certain studies) via MHC Class II and activate T cells. Per the equivalence axioms, 'eosinophil' is reasoned to be a subclass of 'professional antigen presenting cell', though the role of eosinophils as such in the body may be limited.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000041 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000041 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000041 "mature eosinocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000041 "mature eosinophil leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000041 "mature eosinophil leukocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000041 "Eosinophils are CD125-positive (IL-5R), GM-CSFR-positive, IL-3R-positive, VLA4-positive. They can also express MHC Class I & II, CD4, CD9, CD11a, CD11b, CD11c, CD13, CD15, CD16, CD17, CD18, CD24, CD25,CD28, CD29, CD32, CD33, CD35, CD37, CD39, CD43, CD44, CD45, CD45RB, CD45RO, CD46, CD47, CD48, CD49d, CD49f, CD50, CD52, CD53, CD54, CD55, CD58, CD59, CD62L, CD63, CD65, CD66, CD69, CD71, CD76, CD80, CD81, CD82, CD86, CD87, CD88, CD89, CD92, CD95, CD97, CD98, CD99, CD100, CD101, CD116, CD117, CD119, CD120, CD123, CD124, CD125, CD131, CD137, CD139, CD148, CD149, CD151, CD153, CD156, CD162, CD161, CD162, CD165, CD174, CD182, CD183, CD191, CD192, CD193, CD196, CD213, IL9R, ad integrin, beta-7 integrin, FceRI, IL13Ra1, TGFbR, PAFR, LTB4R, C3aR, CystLT1R, CystLT2R, fMLPR, CRTH2 (PGD2 receptor), histamine 4R, IDO, KYN, PAR-2, Siglec-8, Siglec-10, LIR1, LIR2, LIR3, LIR7, TLR7, TLR8, and VLA-4. Eosinophils can also secrete CXCL1, eotaxin-1, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-16, IL-18, IFN-gamma, LTC4, MIP-1alpha, NGF, PAF, RANTES, substance P, TGF-alpha, TGF-beta, TNF-alpha, and VIP.")
AnnotationAssertion(rdfs:label obo:CL_0000041 "mature eosinophil")
EquivalentClasses(obo:CL_0000041 ObjectIntersectionOf(obo:CL_0000771 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007152) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014046) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014047) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000022006) ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009129) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002495) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002540) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045730)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000041 obo:CL_0000771)
SubClassOf(obo:CL_0000041 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000774))

# Class: obo:CL_0000042 (neutrophilic myeloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") obo:IAO_0000115 obo:CL_0000042 "A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000042 "neutrophilic granuloblast")
AnnotationAssertion(rdfs:comment obo:CL_0000042 "These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.")
AnnotationAssertion(rdfs:label obo:CL_0000042 "neutrophilic myeloblast")
EquivalentClasses(obo:CL_0000042 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010799) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014362) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000042 obo:CL_0000835)
SubClassOf(obo:CL_0000042 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000834))

# Class: obo:CL_0000043 (mature basophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18466030") Annotation(oboInOwl:hasDbXref "PMID:19231594") Annotation(oboInOwl:hasDbXref "PMID:20837449") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000043 "A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000043 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000043 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000043 "BTO:0001026")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000043 "CALOHA:TS-0688")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000043 "mature basophil leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000043 "mature basophil leukocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000043 "Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4.")
AnnotationAssertion(rdfs:label obo:CL_0000043 "mature basophil")
EquivalentClasses(obo:CL_0000043 ObjectIntersectionOf(obo:CL_0000767 ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002349) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002351) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032616) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048295)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000043 obo:CL_0000767)
SubClassOf(obo:CL_0000043 obo:CL_0002274)
SubClassOf(obo:CL_0000043 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000770))

# Class: obo:CL_0000044 (obo:CL_0000044)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000044 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000044 obo:CL_0000051)
AnnotationAssertion(owl:deprecated obo:CL_0000044 "true"^^xsd:boolean)

# Class: obo:CL_0000045 (obsolete thymus processed stem cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000045 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000045 "Consider using term 'pro-T cell ; CL:0000827' or the term 'thymocyte ; CL:0000893' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000045 "obsolete thymus processed stem cell")
AnnotationAssertion(owl:deprecated obo:CL_0000045 "true"^^xsd:boolean)

# Class: obo:CL_0000046 (obsolete bursa processed stem cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000046 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000046 "Consider using term 'pro-B cell ; CL:0000826' or the term 'immature B cell ; CL:0000816 or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000046 "obsolete bursa processed stem cell")
AnnotationAssertion(owl:deprecated obo:CL_0000046 "true"^^xsd:boolean)

# Class: obo:CL_0000047 (neural stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30639325") obo:IAO_0000115 obo:CL_0000047 "An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000047 "BTO:0002881")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000047 "CALOHA:TS-2360")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000047 "FMA:86684")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000047 "NSC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16305818") oboInOwl:hasExactSynonym obo:CL_0000047 "neuronal stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000047 "neural stem cell")
SubClassOf(obo:CL_0000047 obo:CL_0002319)
SubClassOf(obo:CL_0000047 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0000048 (multi fate stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000048 "A stem cell that can give rise to multiple lineages of cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000048 "FMA:84789")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000048 "multi-fate stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000048 "multifate stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000048 "multipotent cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000048 "multipotent stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000048 "multi fate stem cell")
EquivalentClasses(obo:CL_0000048 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001402) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))

# Class: obo:CL_0000049 (common myeloid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasDbXref "MESH:D023461") obo:IAO_0000115 obo:CL_0000049 "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000049 "BTO:0004730")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000049 "common myeloid precursor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000049 "CFU-GEMM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000049 "CFU-S")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000049 "CMP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0000049 "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0000049 "multipotential myeloid stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0000049 "myeloid stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0000049 "pluripotent stem cell (bone marrow)")
AnnotationAssertion(rdfs:comment obo:CL_0000049 "This cell type is intended to be compatible with any vertebrate common myeloid progenitor.  For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059).")
AnnotationAssertion(rdfs:label obo:CL_0000049 "common myeloid progenitor")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000049 obo:CL_0002032)
DisjointClasses(obo:CL_0000049 obo:CL_0000050)
DisjointClasses(obo:CL_0000049 obo:CL_0000051)
DisjointClasses(obo:CL_0000049 obo:CL_0000557)

# Class: obo:CL_0000050 (megakaryocyte-erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D055015") Annotation(oboInOwl:hasDbXref "PMID:16647566") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell") obo:IAO_0000115 obo:CL_0000050 "A progenitor cell committed to the megakaryocyte and erythroid lineages.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "CFU-EM")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "CFU-MegE")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "MEP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "Meg/E progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "colony forming unit erythroid megakaryocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "megakaryocyte/erythrocyte progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "megakaryocyte/erythroid progenitor cell")
AnnotationAssertion(rdfs:comment obo:CL_0000050 "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.")
AnnotationAssertion(rdfs:label obo:CL_0000050 "megakaryocyte-erythroid progenitor cell")
EquivalentClasses(obo:CL_0000050 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030218) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030219)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000050 obo:CL_0002032)
SubClassOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049))
DisjointClasses(obo:CL_0000050 obo:CL_0000557)
DisjointClasses(obo:CL_0000050 obo:CL_0002009)

# Class: obo:CL_0000051 (common lymphoid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:10407577") Annotation(oboInOwl:hasDbXref "PMID:16551251") obo:IAO_0000115 obo:CL_0000051 "A oligopotent progenitor cell committed to the lymphoid lineage.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000051 "common lymphocyte precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000051 "common lymphocyte progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000051 "common lymphoid precursor")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000051 "CLP")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000051 "ELP")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000051 "committed lymphopoietic stem cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000051 "early lymphocyte progenitor")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000051 "lymphoid stem cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000051 "lymphopoietic stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0000051 "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000051 "common lymphoid progenitor")
EquivalentClasses(obo:CL_0000051 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000051 obo:CL_0002032)

# Class: obo:CL_0000052 (totipotent stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000052 "A stem cell from which all cells of the body can form.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000052 "FMA:84790")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000052 "MESH:D039901")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000052 "totipotential stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000052 "totipotent stem cell")
SubClassOf(obo:CL_0000052 obo:CL_0000723)

# Class: obo:CL_0000053 (obo:CL_0000053)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000053 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000053 obo:CL_0000059)
AnnotationAssertion(owl:deprecated obo:CL_0000053 "true"^^xsd:boolean)

# Class: obo:CL_0000054 (obsolete bone matrix secreting cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000054 <https://github.com/obophenotype/cell-ontology/issues/2698>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000054 obo:CL_0000062)
AnnotationAssertion(rdfs:comment obo:CL_0000054 "synonymous with 'osteoblast'")
AnnotationAssertion(rdfs:label obo:CL_0000054 "obsolete bone matrix secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000054 "true"^^xsd:boolean)

# Class: obo:CL_0000055 (obsolete non-terminally differentiated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000055 "OBSOLETE. A precursor cell with a limited number of potential fates.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000055 "https://github.com/obophenotype/cell-ontology/issues/2922")
AnnotationAssertion(oboInOwl:consider obo:CL_0000055 obo:CL_0011026)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000055 "BTO:0000125")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000055 "FMA:84782")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000055 "blast cell")
AnnotationAssertion(rdfs:comment obo:CL_0000055 "Redundant grouping term")
AnnotationAssertion(rdfs:comment obo:CL_0000055 "define using PATO mulit-potent or oligopotent?")
AnnotationAssertion(rdfs:label obo:CL_0000055 "obsolete non-terminally differentiated cell")
AnnotationAssertion(owl:deprecated obo:CL_0000055 "true"^^xsd:boolean)

# Class: obo:CL_0000056 (myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D032446") Annotation(oboInOwl:hasDbXref "PMID:21849021") obo:IAO_0000115 obo:CL_0000056 "A cell that is commited to differentiating into a muscle cell.  Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes.  Myoblasts also occur as transient populations of cells in muscles undergoing repair.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000056 "BTO:0000222")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000056 "CALOHA:TS-0650")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000056 "FMA:70335")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000056 "VHOG:0001529")
AnnotationAssertion(rdfs:label obo:CL_0000056 "myoblast")
SubClassOf(obo:CL_0000056 obo:CL_0000680)

# Class: obo:CL_0000057 (fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "MESH:D005347") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Fibroblast") obo:IAO_0000115 obo:CL_0000057 "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000057 "BTO:0000452")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000057 "CALOHA:TS-0362")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000057 "FMA:63877")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000057 "NCIT:C12482")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000057 "VHOG:0001482")
AnnotationAssertion(rdfs:comment obo:CL_0000057 "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000057 "fibroblast")
SubClassOf(obo:CL_0000057 obo:CL_0000499)
SubClassOf(obo:CL_0000057 obo:CL_0002320)
SubClassOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000058 (chondroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000058 "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000058 "BTO:0003607")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000058 "FMA:66783")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000058 "chrondoplast")
AnnotationAssertion(rdfs:label obo:CL_0000058 "chondroblast")
SubClassOf(obo:CL_0000058 obo:CL_0002320)
SubClassOf(obo:CL_0000058 obo:CL_0011026)
SubClassOf(obo:CL_0000058 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007009))
SubClassOf(obo:CL_0000058 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0002418))

# Class: obo:CL_0000059 (ameloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "MESH:D000565") obo:IAO_0000115 obo:CL_0000059 "Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000059 "BTO:0001663")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000059 "FMA:70576")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000059 "amelocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000059 "enamel secreting cell")
AnnotationAssertion(rdfs:comment obo:CL_0000059 "non-encoded relationship from VSAO produces VSAO:0000066")
AnnotationAssertion(rdfs:label obo:CL_0000059 "ameloblast")
SubClassOf(obo:CL_0000059 obo:CL_0000146)
SubClassOf(obo:CL_0000059 obo:CL_0000151)
SubClassOf(obo:CL_0000059 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0000059 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007000))
SubClassOf(obo:CL_0000059 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0097186))
SubClassOf(obo:CL_0000059 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001763))
SubClassOf(obo:CL_0000059 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0001752))

# Class: obo:CL_0000060 (odontoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000060 "Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000060 "BTO:0001769")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000060 "CALOHA:TS-0696")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000060 "FMA:62999")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000060 "MESH:D009804")
AnnotationAssertion(rdfs:comment obo:CL_0000060 "legacy def: One of the cells forming the outer surface of dental pulp that produces tooth dentin.")
AnnotationAssertion(rdfs:label obo:CL_0000060 "odontoblast")
SubClassOf(obo:CL_0000060 obo:CL_0002148)
SubClassOf(obo:CL_0000060 obo:CL_0002159)
SubClassOf(obo:CL_0000060 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0000060 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007003))
SubClassOf(obo:CL_0000060 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0001751))

# Class: obo:CL_0000061 (cementoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "ISBN:0781733901") obo:IAO_0000115 obo:CL_0000061 "Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000061 "CALOHA:TS-1164")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000061 "FMA:63002")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000061 "cementum secreting cell")
AnnotationAssertion(rdfs:comment obo:CL_0000061 "Legacy def: A cell of ectomesenchymal origin that aids in the formation the cementum layer on the roots of teeth.")
AnnotationAssertion(rdfs:label obo:CL_0000061 "cementoblast")
SubClassOf(obo:CL_0000061 obo:CL_0000062)
SubClassOf(obo:CL_0000061 obo:CL_0000151)
SubClassOf(obo:CL_0000061 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0000061 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007002))
SubClassOf(obo:CL_0000061 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0001753))

# Class: obo:CL_0000062 (osteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "MESH:D010006") obo:IAO_0000115 obo:CL_0000062 "Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000062 "BTO:0001593")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000062 "CALOHA:TS-0720")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000062 "FMA:66780")
AnnotationAssertion(rdfs:comment obo:CL_0000062 "non-encoded relationships from VSAO - capable_of_producing VSAO:0000020")
AnnotationAssertion(rdfs:label obo:CL_0000062 "osteoblast")
SubClassOf(obo:CL_0000062 obo:CL_0002320)
SubClassOf(obo:CL_0000062 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007010))
SubClassOf(obo:CL_0000062 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0008883))

# Class: obo:CL_0000063 (obsolete cell by histology)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000063 "OBSOLETE: A classification of cells by their microscopic appearance.")
AnnotationAssertion(oboInOwl:consider obo:CL_0000063 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000063 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000063 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000063 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its microscopic appearance. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000063 "obsolete cell by histology")
AnnotationAssertion(owl:deprecated obo:CL_0000063 "true"^^xsd:boolean)

# Class: obo:CL_0000064 (ciliated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000064 "A cell that has a filiform extrusion of the cell surface.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000064 "VHOG:0001532")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000064 "XAO:0000031")
AnnotationAssertion(rdfs:label obo:CL_0000064 "ciliated cell")
EquivalentClasses(obo:CL_0000064 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929)))

# Class: obo:CL_0000065 (ependymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:34335193") Annotation(oboInOwl:hasDbXref "PMID:37008045") Annotation(oboInOwl:hasDbXref "PMID:9550134") Annotation(oboInOwl:hasDbXref "doi:/10.3389/fncel.2021.703951") Annotation(oboInOwl:hasDbXref "https://www.britannica.com/science/ependymal-cell") obo:IAO_0000115 obo:CL_0000065 "A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000065 "BTO:0001724")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000065 "FMA:70550")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.53347/rID-51713") oboInOwl:hasNarrowSynonym obo:CL_0000065 "ependymocyte")
AnnotationAssertion(rdfs:label obo:CL_0000065 "ependymal cell")
EquivalentClasses(obo:CL_0000065 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004670)))
SubClassOf(obo:CL_0000065 obo:CL_0000125)
SubClassOf(obo:CL_0000065 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929))
SubClassOf(obo:CL_0000065 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_0000681))

# Class: obo:CL_0000066 (epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D004847") obo:IAO_0000115 obo:CL_0000066 "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000066 "BTO:0000414")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000066 "CALOHA:TS-2026")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000066 "CARO:0000077")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000066 "FMA:66768")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000066 "WBbt:0003672")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000066 "epitheliocyte")
AnnotationAssertion(rdfs:label obo:CL_0000066 "epithelial cell")
AnnotationAssertion(foaf:depiction obo:CL_0000066 "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI)
SubClassOf(obo:CL_0000066 obo:CL_0000000)
SubClassOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000483))
DisjointClasses(obo:CL_0000066 obo:CL_0000738)

# Class: obo:CL_0000067 (ciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000067 "An epithelial cell that has a cilia.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000067 "FMA:70605")
AnnotationAssertion(rdfs:label obo:CL_0000067 "ciliated epithelial cell")
EquivalentClasses(obo:CL_0000067 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929)))

# Class: obo:CL_0000068 (duct epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000068 "An epithelial cell that is part of a duct.")
AnnotationAssertion(rdfs:label obo:CL_0000068 "duct epithelial cell")
EquivalentClasses(obo:CL_0000068 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000058)))
SubClassOf(obo:CL_0000068 obo:CL_0000066)

# Class: obo:CL_0000069 (branched duct epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000069 "branched duct epithelial cell")
SubClassOf(obo:CL_0000069 obo:CL_0000068)

# Class: obo:CL_0000070 (obsolete epithelial cell of gland)

AnnotationAssertion(rdfs:label obo:CL_0000070 "obsolete epithelial cell of gland")
AnnotationAssertion(owl:deprecated obo:CL_0000070 "true"^^xsd:boolean)

# Class: obo:CL_0000071 (blood vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000071 "An endothelial cell that lines the vasculature.")
AnnotationAssertion(rdfs:label obo:CL_0000071 "blood vessel endothelial cell")
EquivalentClasses(obo:CL_0000071 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981)))
SubClassOf(obo:CL_0000071 obo:CL_0002139)
SubClassOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004638))

# Class: obo:CL_0000072 (non-branched duct epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000072 "non-branched duct epithelial cell")
SubClassOf(obo:CL_0000072 obo:CL_0000068)
SubClassOf(obo:CL_0000072 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0000073 (obsolete barrier epithelial cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000073 <https://github.com/obophenotype/cell-ontology/issues/1149>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000073 obo:CL_0000215)
AnnotationAssertion(rdfs:label obo:CL_0000073 "obsolete barrier epithelial cell")
AnnotationAssertion(owl:deprecated obo:CL_0000073 "true"^^xsd:boolean)

# Class: obo:CL_0000074 (obsolete epithem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") Annotation(oboInOwl:hasDbXref "PMID:12662305") obo:IAO_0000115 obo:CL_0000074 "Obsolete. Use PO:0000066 from Plant Ontology instead. A cell that constitutes the mesophyll of a hydathode and is located between the xylem endings and the epidermis. Proposed to be involved in the retrieval of solutes from the xylem sap.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000074 obo:PO_0000066)
AnnotationAssertion(rdfs:label obo:CL_0000074 "obsolete epithem cell")
AnnotationAssertion(owl:deprecated obo:CL_0000074 "true"^^xsd:boolean)

# Class: obo:CL_0000075 (columnar/cuboidal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0002065") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000075 "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.")
AnnotationAssertion(rdfs:label obo:CL_0000075 "columnar/cuboidal epithelial cell")
SubClassOf(obo:CL_0000075 obo:CL_0000066)

# Class: obo:CL_0000076 (squamous epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000076 "CALOHA:TS-1249")
AnnotationAssertion(rdfs:label obo:CL_0000076 "squamous epithelial cell")
SubClassOf(obo:CL_0000076 obo:CL_0000066)

# Class: obo:CL_0000077 (mesothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "PMID:26106328") obo:IAO_0000115 obo:CL_0000077 "A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000077 "FMA:66773")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000077 "mesotheliocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26106328") rdfs:comment obo:CL_0000077 "Mesothelial cells, which morphologically resemble squamous epithelial cells, express both epithelial markers (cytokeratins) and mesenchymal markers (vimentin), reflecting their mesodermal origin. They feature surface microvilli and apical-basal polarity. Under certain conditions, they can undergo mesothelial-to-mesenchymal transition. These cells also produce extracellular matrix proteins, maintain serosal homeostasis, and facilitate fluid transport.")
AnnotationAssertion(rdfs:label obo:CL_0000077 "mesothelial cell")
SubClassOf(obo:CL_0000077 obo:CL_0000076)
SubClassOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001136))
SubClassOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0000078 (peridermal cell)

AnnotationAssertion(rdfs:label obo:CL_0000078 "peridermal cell")
EquivalentClasses(obo:CL_0000078 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003055)))

# Class: obo:CL_0000079 (stratified epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Epithelium") Annotation(oboInOwl:hasDbXref "doi:/10.1016/B978-0-12-410424-2.00003-2") Annotation(oboInOwl:hasDbXref "https://www.biologyonline.com/dictionary/stratified-epithelium") obo:IAO_0000115 obo:CL_0000079 "An epithelial cell, organized into multiple layers, with only the basal layer being in contact with the basement membrane.")
AnnotationAssertion(rdfs:label obo:CL_0000079 "stratified epithelial cell")
SubClassOf(obo:CL_0000079 obo:CL_0000066)
SubClassOf(obo:CL_0000079 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000357))

# Class: obo:CL_0000080 (circulating cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000080 "A cell which moves among different tissues of the body, via blood, lymph, or other medium.")
AnnotationAssertion(rdfs:label obo:CL_0000080 "circulating cell")
EquivalentClasses(obo:CL_0000080 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000179)))

# Class: obo:CL_0000081 (blood cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000081 "A cell found predominately in the blood.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000081 "FMA:62844")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000081 "MESH:D001773")
AnnotationAssertion(rdfs:label obo:CL_0000081 "blood cell")
EquivalentClasses(obo:CL_0000081 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000081 obo:CL_0000988)

# Class: obo:CL_0000082 (epithelial cell of lung)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000082 "An epithelial cell of the lung.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000082 "BTO:0004299")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000082 "lung epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0000082 "epithelial cell of lung")
EquivalentClasses(obo:CL_0000082 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000115)))

# Class: obo:CL_0000083 (epithelial cell of pancreas)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000083 "An epithelial cell of the pancreas.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000083 "BTO:0000028")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000083 "pancreas epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000083 "pancreatic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0000083 "epithelial cell of pancreas")
EquivalentClasses(obo:CL_0000083 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))
SubClassOf(obo:CL_0000083 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000223))

# Class: obo:CL_0000084 (T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000084 "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000084 "BTO:0000782")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000084 "CALOHA:TS-1001")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000084 "FMA:62870")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000084 "MESH:D013601")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000084 "VHOG:0001479")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000084 "T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000084 "T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000084 "T-lymphocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000084 "immature T cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000084 "mature T cell")
AnnotationAssertion(rdfs:label obo:CL_0000084 "T cell")
EquivalentClasses(obo:CL_0000084 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002456)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000084 obo:CL_0000542)
SubClassOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000827))
DisjointClasses(obo:CL_0000084 obo:CL_0000945)

# Class: obo:CL_0000085 (obsolete germ line stem cell (sensu Vertebrata))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000085 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000085 obo:CL_0000014)
AnnotationAssertion(rdfs:comment obo:CL_0000085 "Obsoleted as there is no need for a term specific for vertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0000085 "obsolete germ line stem cell (sensu Vertebrata)")
AnnotationAssertion(owl:deprecated obo:CL_0000085 "true"^^xsd:boolean)

# Class: obo:CL_0000086 (obsolete germ line stem cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000086 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000086 obo:CL_0000014)
AnnotationAssertion(rdfs:comment obo:CL_0000086 "Obsoleted as there is no need for a term specific for nematods and protostomes.")
AnnotationAssertion(rdfs:label obo:CL_0000086 "obsolete germ line stem cell (sensu Nematoda and Protostomia)")
AnnotationAssertion(owl:deprecated obo:CL_0000086 "true"^^xsd:boolean)

# Class: obo:CL_0000087 (obsolete male germ line stem cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000087 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000087 obo:CL_0000016)
AnnotationAssertion(rdfs:comment obo:CL_0000087 "Obsoleted as there is no need for a term specific for nematods and protostomes.")
AnnotationAssertion(rdfs:label obo:CL_0000087 "obsolete male germ line stem cell (sensu Nematoda and Protostomia)")
AnnotationAssertion(owl:deprecated obo:CL_0000087 "true"^^xsd:boolean)

# Class: obo:CL_0000088 (obsolete female germ line stem cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000088 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000088 obo:CL_0000022)
AnnotationAssertion(rdfs:comment obo:CL_0000088 "Obsoleted as there is no need for a term specific for nematods and protostomes.")
AnnotationAssertion(rdfs:label obo:CL_0000088 "obsolete female germ line stem cell (sensu Nematoda and Protostomia)")
AnnotationAssertion(owl:deprecated obo:CL_0000088 "true"^^xsd:boolean)

# Class: obo:CL_0000089 (obsolete male germ line stem cell (sensu Vertebrata))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000089 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000089 obo:CL_0000016)
AnnotationAssertion(rdfs:comment obo:CL_0000089 "Obsoleted as there is no need for a term specific for vertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0000089 "obsolete male germ line stem cell (sensu Vertebrata)")
AnnotationAssertion(owl:deprecated obo:CL_0000089 "true"^^xsd:boolean)

# Class: obo:CL_0000090 (obsolete female germ line stem cell (sensu Vertebrata))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000090 <https://github.com/obophenotype/cell-ontology/issues/1935>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000090 obo:CL_0000022)
AnnotationAssertion(rdfs:comment obo:CL_0000090 "Obsoleted as there is no need for a term specific for vertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0000090 "obsolete female germ line stem cell (sensu Vertebrata)")
AnnotationAssertion(owl:deprecated obo:CL_0000090 "true"^^xsd:boolean)

# Class: obo:CL_0000091 (Kupffer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "MESH:D007728") Annotation(oboInOwl:hasDbXref "PMID:15771589") Annotation(oboInOwl:hasDbXref "PMID:17105582") obo:IAO_0000115 obo:CL_0000091 "A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000091 "BTO:0000685")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000091 "FMA:14656")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "hepatic macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "littoral cell of hepatic sinusoid")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "liver macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "macrophagocytus stellatus")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "stellate cell of von Kupffer")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "von Kupffer cell")
AnnotationAssertion(rdfs:comment obo:CL_0000091 "Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythrocytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positive, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2.")
AnnotationAssertion(rdfs:label obo:CL_0000091 "Kupffer cell")
EquivalentClasses(obo:CL_0000091 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000091 obo:CL_0000864)

# Class: obo:CL_0000092 (osteoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:10428500") Annotation(oboInOwl:hasDbXref "PMID:15055519") Annotation(oboInOwl:hasDbXref "PMID:17380158") obo:IAO_0000115 obo:CL_0000092 "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000092 "BTO:0000968")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000092 "CALOHA:TS-0721")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000092 "FMA:66781")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000092 "MESH:D010010")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000092 "chondroclast")
AnnotationAssertion(rdfs:comment obo:CL_0000092 "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000092 "osteoclast")
EquivalentClasses(obo:CL_0000092 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001474) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001850) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001937) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007597) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000011178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001954) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045453)))
SubClassOf(obo:CL_0000092 obo:CL_0000518)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0000766)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0001035)
SubClassOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))

# Class: obo:CL_0000093 (obsolete osteochondroclast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000093 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000093 "Consider using 'osteoclast ; CL:0000092' instead.")
AnnotationAssertion(rdfs:label obo:CL_0000093 "obsolete osteochondroclast")
AnnotationAssertion(owl:deprecated obo:CL_0000093 "true"^^xsd:boolean)

# Class: obo:CL_0000094 (granulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D006098") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Granulocyte") obo:IAO_0000115 obo:CL_0000094 "A leukocyte with abundant granules in the cytoplasm.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000094 "BTO:0000539")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000094 "BTO:0001026")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000094 "CALOHA:TS-0422")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000094 "FMA:62854")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000094 "granular leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000094 "granular leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000094 "polymorphonuclear leukocyte")
AnnotationAssertion(rdfs:label obo:CL_0000094 "granulocyte")
EquivalentClasses(obo:CL_0000094 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030141) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001332) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001969) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000094 obo:CL_0000766)

# Class: obo:CL_0000095 (neuron associated cell)

AnnotationAssertion(rdfs:label obo:CL_0000095 "neuron associated cell")
SubClassOf(obo:CL_0000095 obo:CL_0002319)
SubClassOf(obo:CL_0000095 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0000096 (mature neutrophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D009504") Annotation(oboInOwl:hasDbXref "PMID:11138776") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") Annotation(oboInOwl:hasDbXref "PMID:7880385") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000096 "A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000096 "poly")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000096 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000096 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000096 "BTO:0003473")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "PMN")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "mature neutrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "mature neutrophil leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "mature neutrophil leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "mature neutrophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "mature neutrophilic leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "polymorphonuclear neutrophil")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "polynuclear neutrophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "polynuclear neutrophilic leukocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000096 "Neutrophils are also capable of secreting GRO-alpha, IL-1beta, IL-1ra, IL-3, IL-12, IP-10, MIG, MIP-1alpha, MIP-1beta, TGF-beta, TNF-alpha, VEGF, and anti-microbial peptides. They can positively influence the chemotaxis of basophils, T-cells, monocytes, macrophages, dendritic cells, and other neutrophils. Neutrophils are also CD35-positive, CD64-positive, CD89-positive, CD184-positive, and fMLP receptor-positive Ly-6G-positive (mouse), TLR2-low, TLR4-low, and lineage-negative (CD2, CD3, CD5, CD9, CD19, CD36, CD49d, CD56, CD61, CD235a (glycophorin-A)).")
AnnotationAssertion(rdfs:label obo:CL_0000096 "mature neutrophil")
EquivalentClasses(obo:CL_0000096 ObjectIntersectionOf(obo:CL_0000775 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017500) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010799) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001256) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001257) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001944) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000007597) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002536) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002690) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032637)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000096 obo:CL_0000775)

# Class: obo:CL_0000097 (mast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") Annotation(oboInOwl:hasDbXref "MESH:D008407") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") Annotation(oboInOwl:hasDbXref "PMCID:PMC2855166") Annotation(oboInOwl:hasDbXref "PMID:15153310") Annotation(oboInOwl:hasDbXref "PMID:16455980") Annotation(oboInOwl:hasDbXref "PMID:19671378") Annotation(oboInOwl:hasDbXref "PMID:212366338") Annotation(oboInOwl:hasDbXref "PMID:9354811") obo:IAO_0000115 obo:CL_0000097 "A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000097 "BTO:0000830")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000097 "CALOHA:TS-0603")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000097 "FMA:66784")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000097 "histaminocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000097 "labrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000097 "mastocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:068340007X") oboInOwl:hasRelatedSynonym obo:CL_0000097 "tissue basophil")
AnnotationAssertion(rdfs:comment obo:CL_0000097 "Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5.")
AnnotationAssertion(rdfs:label obo:CL_0000097 "mast cell")
EquivalentClasses(obo:CL_0000097 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030141) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006169) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002349) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002539) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002660) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002690) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030210) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000097 obo:CL_0000766)
SubClassOf(obo:CL_0000097 obo:CL_0002274)
SubClassOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000831))

# Class: obo:CL_0000098 (sensory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000098 "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000098 "neuroepithelial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000098 "BTO:0004301")
AnnotationAssertion(rdfs:comment obo:CL_0000098 "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).")
AnnotationAssertion(rdfs:label obo:CL_0000098 "sensory epithelial cell")
EquivalentClasses(obo:CL_0000098 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))
SubClassOf(obo:CL_0000098 obo:CL_0000197)

# Class: obo:CL_0000099 (interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D007395") obo:IAO_0000115 obo:CL_0000099 "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000099 "BTO:0003811")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000099 "FMA:67313")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000099 "WBbt:0005113")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000099 "CNS interneuron")
AnnotationAssertion(rdfs:label obo:CL_0000099 "interneuron")
SubClassOf(obo:CL_0000099 obo:CL_0000540)
SubClassOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))

# Class: obo:CL_0000100 (motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009046") Annotation(oboInOwl:hasDbXref "PMID:16875686") obo:IAO_0000115 obo:CL_0000100 "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000100 "BTO:0000312")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000100 "FMA:83617")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000100 "WBbt:0005409")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000100 "motoneuron")
AnnotationAssertion(rdfs:label obo:CL_0000100 "motor neuron")
SubClassOf(obo:CL_0000100 obo:CL_0000527)

# Class: obo:CL_0000101 (sensory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000101 "Any neuron having a sensory function; an afferent neuron conveying sensory impulses.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000101 "BTO:0001037")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000101 "FMA:84649")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000101 "MESH:D011984")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000101 "WBbt:0005759")
AnnotationAssertion(rdfs:label obo:CL_0000101 "sensory neuron")
EquivalentClasses(obo:CL_0000101 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))
SubClassOf(obo:CL_0000101 obo:CL_0000526)

# Class: obo:CL_0000102 (polymodal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23749412") Annotation(oboInOwl:hasDbXref "PMID:36381588") obo:IAO_0000115 obo:CL_0000102 "A neuron type that respond to multiple stimuli such as mechanical, thermal and chemical. This neuron type is responsible for integrating different types of sensory inputs, allowing organisms to respond appropriately to diverse environmental challenges.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23749412") oboInOwl:hasRelatedSynonym obo:CL_0000102 "polymodal sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0000102 "polymodal neuron")
SubClassOf(obo:CL_0000102 obo:CL_2000032)

# Class: obo:CL_0000103 (bipolar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0444009442") obo:IAO_0000115 obo:CL_0000103 "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000103 "FMA:67282")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000103 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000103 "bipolar neuron")
EquivalentClasses(obo:CL_0000103 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070006)))

# Class: obo:CL_0000104 (multipolar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67287") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000104 "A neuron with three or more neurites, usually an axon and multiple dendrites.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000104 "FMA:67287")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000104 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000104 "multipolar neuron")
SubClassOf(obo:CL_0000104 obo:CL_0000540)
SubClassOf(obo:CL_0000104 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070026))
SubClassOf(obo:CL_0000104 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0000105 (pseudounipolar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67305") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000105 "Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000105 "FMA:67305")
AnnotationAssertion(rdfs:label obo:CL_0000105 "pseudounipolar neuron")
SubClassOf(obo:CL_0000105 obo:CL_2000032)

# Class: obo:CL_0000106 (unipolar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67278") Annotation(oboInOwl:hasDbXref "GOC:nv") obo:IAO_0000115 obo:CL_0000106 "Neuron with one neurite that extends from the cell body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000106 "FMA:67278")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000106 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000106 "unipolar neuron")
SubClassOf(obo:CL_0000106 obo:CL_2000032)

# Class: obo:CL_0000107 (autonomic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000107 "A neuron whose cell body is within an autonomic ganglion.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000107 "FMA:80121")
AnnotationAssertion(rdfs:label obo:CL_0000107 "autonomic neuron")
EquivalentClasses(obo:CL_0000107 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002410)))
SubClassOf(obo:CL_0000107 obo:CL_0000540)

# Class: obo:CL_0000108 (cholinergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000108 "A neuron that uses acetylcholine as a vesicular neurotransmitter.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000108 "BTO:0004902")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000108 "FMA:84796")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000108 "MESH:D059329")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000108 "WBbt:0006840")
AnnotationAssertion(rdfs:label obo:CL_0000108 "cholinergic neuron")
EquivalentClasses(obo:CL_0000108 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055)))

# Class: obo:CL_0000109 (adrenergic neuron)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000109 "MESH:D059331")
AnnotationAssertion(rdfs:label obo:CL_0000109 "adrenergic neuron")
SubClassOf(obo:CL_0000109 obo:CL_0000540)
SubClassOf(obo:CL_0000109 obo:CL_4033050)

# Class: obo:CL_0000110 (peptidergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23040809") Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012589762-4/50021-9") obo:IAO_0000115 obo:CL_0000110 "A neuron that uses neuropeptides as transmitters.")
AnnotationAssertion(rdfs:label obo:CL_0000110 "peptidergic neuron")
SubClassOf(obo:CL_0000110 obo:CL_0000540)
SubClassOf(obo:CL_0000110 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002790))

# Class: obo:CL_0000111 (obsolete peripheral neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000111 "OBSOLETE A neuron that is part of nerve found outside the central nervous system.")
AnnotationAssertion(obo:IAO_0000231 obo:CL_0000111 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000111 <https://github.com/obophenotype/cell-ontology/issues/1069>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000111 obo:CL_2000032)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000111 "FMA:84664")
AnnotationAssertion(rdfs:comment obo:CL_0000111 "Merging into CL:2000032.")
AnnotationAssertion(rdfs:label obo:CL_0000111 "obsolete peripheral neuron")
AnnotationAssertion(owl:deprecated obo:CL_0000111 "true"^^xsd:boolean)

# Class: obo:CL_0000112 (columnar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34696823") Annotation(oboInOwl:hasDbXref "PMID:37608556") obo:IAO_0000115 obo:CL_0000112 "A neuron of the invertebrate central nervous system. This neuron innervates the central complex (CX) of an invertebrate brain and it forms columnar patterns with its dendrites. It is involved in navigation and spatial processing.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18837039") Annotation(oboInOwl:hasDbXref "PMID:32374034") Annotation(oboInOwl:hasDbXref "PMID:34696823") Annotation(oboInOwl:hasDbXref "PMID:37608556") Annotation(oboInOwl:hasDbXref "PMID:9153131") rdfs:comment obo:CL_0000112 "Columnar neurons have been widely studied in Diptera, locusts, honey bees and other insects. In the mammalian brain, a \"columnar organisation\" is referred to neurons of the neocortex, however these differ from columnar neurons which are found in the insects central nervous system.")
AnnotationAssertion(rdfs:label obo:CL_0000112 "columnar neuron")
SubClassOf(obo:CL_0000112 obo:CL_0000028)
SubClassOf(obo:CL_0000112 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))
SubClassOf(obo:CL_0000112 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000338))
SubClassOf(obo:CL_0000112 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007601))

# Class: obo:CL_0000113 (mononuclear phagocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000113 "A vertebrate phagocyte with a single nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000113 "BTO:0001433")
AnnotationAssertion(rdfs:label obo:CL_0000113 "mononuclear phagocyte")
EquivalentClasses(obo:CL_0000113 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000113 obo:CL_0000518)
SubClassOf(obo:CL_0000113 obo:CL_0000842)

# Class: obo:CL_0000114 (surface ectodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7892198") Annotation(oboInOwl:hasDbXref "Wikipedia:Surface_ectoderm") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2024.07.02.601324") obo:IAO_0000115 obo:CL_0000114 "An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000114 "FMA:72552")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000114 "cell of surface ectoderm")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1101/2024.07.02.601324") oboInOwl:hasExactSynonym obo:CL_0000114 "surface ectoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0000114 "surface ectodermal cell")
EquivalentClasses(obo:CL_0000114 ObjectIntersectionOf(obo:CL_0000221 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000076)))

# Class: obo:CL_0000115 (endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D042783") Annotation(oboInOwl:hasDbXref "PMID:21275341") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Endothelial_cell") Annotation(oboInOwl:hasDbXref "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855") obo:IAO_0000115 obo:CL_0000115 "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000115 "BTO:0001176")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000115 "CALOHA:TS-0278")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000115 "FMA:66772")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000115 "endotheliocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000115 "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].")
AnnotationAssertion(rdfs:label obo:CL_0000115 "endothelial cell")
SubClassOf(obo:CL_0000115 obo:CL_0000000)
SubClassOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0000116 (pioneer neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000116 "Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance.")
AnnotationAssertion(rdfs:label obo:CL_0000116 "pioneer neuron")
SubClassOf(obo:CL_0000116 obo:CL_0000540)

# Class: obo:CL_0000117 (CNS neuron (sensu Vertebrata))

AnnotationAssertion(rdfs:label obo:CL_0000117 "CNS neuron (sensu Vertebrata)")
SubClassOf(obo:CL_0000117 obo:CL_2000029)
SubClassOf(obo:CL_0000117 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))

# Class: obo:CL_0000118 (basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Basket_cell&oldid=951703880") obo:IAO_0000115 obo:CL_0000118 "Basket cells are inhibitory GABAergic interneurons of the brain. In general, dendrites of basket cells are free branching and contain smooth spines. Axons are highly branched. The branched axonal arborizations give rise to basket-like structures that surround the soma of the target cell. Basket cells form axo-somatic synapses, meaning their synapses target somas of other cells.")
AnnotationAssertion(terms:contributor obo:CL_0000118 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000118 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000118 "basket cell")
EquivalentClasses(obo:CL_0000118 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070002) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_0000119 (cerebellar Golgi cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFSTD:sao1415726815") obo:IAO_0000115 obo:CL_0000119 "Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000119 "MESH:D000080906")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000119 "Golgi cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000119 "Golgi neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000119 "cerebellar Golgi neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000119 "cerebellum Golgi cell")
AnnotationAssertion(rdfs:label obo:CL_0000119 "cerebellar Golgi cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_0000119 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0000119 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.png>)
SubClassOf(obo:CL_0000119 obo:CL_0011005)
SubClassOf(obo:CL_0000119 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002956))
SubClassOf(obo:CL_0000119 ObjectSomeValuesFrom(obo:RO_0002113 obo:UBERON_0002956))
SubClassOf(obo:CL_0000119 ObjectSomeValuesFrom(obo:RO_0002360 obo:UBERON_0002974))

# Class: obo:CL_0000120 (granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://medical-dictionary.thefreedictionary.com/granule+cell>) obo:IAO_0000115 obo:CL_0000120 "A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000120 "BTO:0003393")
AnnotationAssertion(rdfs:label obo:CL_0000120 "granule cell")
SubClassOf(obo:CL_0000120 obo:CL_0000540)
SubClassOf(obo:CL_0000120 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0000121 (Purkinje cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011689") Annotation(oboInOwl:hasDbXref "PMID:12907269") Annotation(oboInOwl:hasDbXref "PMID:14568361") Annotation(oboInOwl:hasDbXref "PMID:31424738") Annotation(oboInOwl:hasDbXref "PMID:33288911") Annotation(oboInOwl:hasDbXref "PMID:38168772") obo:IAO_0000115 obo:CL_0000121 "An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometres in diameter. Purkinje cells have planar, fan-shaped dendrites that branch extensively with little overlap. This cell type receives synaptic input from parallel fibres, which modulate high-frequency spike activity known as \"simple spikes,\" and climbing fibres, which modulate infrequent calcium spike activity known as \"complex spikes\". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "BTO:0001011")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "CALOHA:TS-0845")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "FMA:67969")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.proghi.2004.07.002") oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellar Purkinje cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38168772") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000121 "PC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000121 "PN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17535929") Annotation(oboInOwl:hasDbXref "PMID:27215193") Annotation(oboInOwl:hasDbXref "PMID:37426070") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.stem.2023.11.013") rdfs:comment obo:CL_0000121 "Neurodegenerative disorders affecting Purkinje cells disrupt motor functions. Some of the neurodegenerative disorders that causes loss and degeration of Purkinje cells are Spinocerebellar ataxias (SCAs) (Josef P Kapfhammer and Etsuko Shimobayashi 2023), Friedreich's ataxia (FRDA) (Kevin C Kemp et al., 2016), Fetal alcohol syndrome (Laurent Servais et al., 2016), Dandy-Walker malformation (Alexander Atamian et al., 2024).")
AnnotationAssertion(rdfs:label obo:CL_0000121 "Purkinje cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_0000121 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0000121 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
SubClassOf(obo:CL_0000121 obo:CL_0000540)
SubClassOf(obo:CL_0000121 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002979))
SubClassOf(obo:CL_0000121 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0000122 (stellate neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:9780123973481") obo:IAO_0000115 obo:CL_0000122 "A neuron that has dendritic processes radiating from the cell body forming a star-like shape.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000122 "BTO:0002316")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000122 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000122 "stellate neuron")
EquivalentClasses(obo:CL_0000122 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070010)))
SubClassOf(obo:CL_0000122 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0000123 (neuron associated cell (sensu Vertebrata))

AnnotationAssertion(rdfs:label obo:CL_0000123 "neuron associated cell (sensu Vertebrata)")
SubClassOf(obo:CL_0000123 obo:CL_0000095)
SubClassOf(obo:CL_0000123 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000124 (obsolete glial cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000124 <https://github.com/obophenotype/cell-ontology/issues/715>)
AnnotationAssertion(rdfs:comment obo:CL_0000124 "This is a grouping class that is no longer needed or wanted.")
AnnotationAssertion(rdfs:label obo:CL_0000124 "obsolete glial cell (sensu Nematoda and Protostomia)")
AnnotationAssertion(owl:deprecated obo:CL_0000124 "true"^^xsd:boolean)

# Class: obo:CL_0000125 (glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009457") obo:IAO_0000115 obo:CL_0000125 "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000125 "BTO:0002606")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000125 "CALOHA:TS-0415")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000125 "FMA:54536")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000125 "neuroglial cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000125 "neuroglia")
AnnotationAssertion(rdfs:comment obo:CL_0000125 "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571")
AnnotationAssertion(rdfs:label obo:CL_0000125 "glial cell")
SubClassOf(obo:CL_0000125 obo:CL_0000095)

# Class: obo:CL_0000126 (macroglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000126 "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000126 "BTO:0000771")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000126 "CALOHA:TS-2027")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000126 "FMA:54538")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000126 "macrogliocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1152/physrev.2001.81.2.871") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000126 "macroglia")
AnnotationAssertion(rdfs:label obo:CL_0000126 "macroglial cell")
SubClassOf(obo:CL_0000126 obo:CL_0000125)
SubClassOf(obo:CL_0000126 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000339))

# Class: obo:CL_0000127 (astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D001253") Annotation(oboInOwl:hasDbXref "PMID:11746784") Annotation(oboInOwl:hasDbXref "PMID:12162730") Annotation(oboInOwl:hasDbXref "PMID:12898703") Annotation(oboInOwl:hasDbXref "PMID:20942978") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Astrocyte") obo:IAO_0000115 obo:CL_0000127 "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000127 "BTO:0000099")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000127 "CALOHA:TS-0060")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000127 "FMA:54537")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000127 "astrocytic glia")
AnnotationAssertion(rdfs:comment obo:CL_0000127 "Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000127 "astrocyte")
SubClassOf(obo:CL_0000127 obo:CL_0000126)

# Class: obo:CL_0000128 (oligodendrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009836") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Oligodendrocyte") obo:IAO_0000115 obo:CL_0000128 "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000128 "BTO:0000962")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000128 "CALOHA:TS-0709")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000128 "FMA:54540")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8734446") oboInOwl:hasExactSynonym obo:CL_0000128 "OLs")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000128 "oligodendroglia")
AnnotationAssertion(rdfs:comment obo:CL_0000128 "Oligodendrocytes are reportedly MDP-positive and CD4-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000128 "oligodendrocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000128 obo:CL_0000126)
SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043209))
SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002453))

# Class: obo:CL_0000129 (microglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "MESH:D017628") Annotation(oboInOwl:hasDbXref "PMID:11517395") Annotation(oboInOwl:hasDbXref "PMID:12430718") Annotation(oboInOwl:hasDbXref "PMID:14561199") Annotation(oboInOwl:hasDbXref "PMID:14612429") Annotation(oboInOwl:hasDbXref "PMID:16177057") Annotation(oboInOwl:hasDbXref "PMID:19461673") Annotation(oboInOwl:hasDbXref "PMID:2089275") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Microglia") obo:IAO_0000115 obo:CL_0000129 "A transcriptomically distinct central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000129 "brain macrophage")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000129 "BTO:0000078")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000129 "BTO:0000962")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000129 "FMA:54539")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000129 "brain-resident macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/") oboInOwl:hasExactSynonym obo:CL_0000129 "hortega cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/") oboInOwl:hasExactSynonym obo:CL_0000129 "microgliocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000129 "MF.microglia.CNS")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000129 "microglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23616747") rdfs:comment obo:CL_0000129 "Unlike macroglial cells, microglial cells  arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000129 "microglial cell")
EquivalentClasses(obo:CL_0000129 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087)))
SubClassOf(obo:CL_0000129 obo:CL_0000878)
SubClassOf(obo:CL_0000129 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))
SubClassOf(obo:CL_0000129 ObjectSomeValuesFrom(obo:RO_0002202 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001040))))

# Class: obo:CL_0000130 (neuron associated cell (sensu Nematoda and Protostomia))

AnnotationAssertion(rdfs:label obo:CL_0000130 "neuron associated cell (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000130 obo:CL_0000095)
SubClassOf(obo:CL_0000130 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33317))

# Class: obo:CL_0000131 (gut endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26564856") obo:IAO_0000115 obo:CL_0000131 "An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream.")
AnnotationAssertion(rdfs:label obo:CL_0000131 "gut endothelial cell")
EquivalentClasses(obo:CL_0000131 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001555)))
SubClassOf(obo:CL_0000131 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000223))

# Class: obo:CL_0000132 (corneal endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:21976958") Annotation(oboInOwl:hasDbXref "PMID:23284695") Annotation(oboInOwl:hasDbXref "PMID:34741068") Annotation(oboInOwl:hasDbXref "PMID:36769303") obo:IAO_0000115 obo:CL_0000132 "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000132 "CALOHA:TS-0172")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000132 "FMA:70614")
AnnotationAssertion(rdfs:label obo:CL_0000132 "corneal endothelial cell")
SubClassOf(obo:CL_0000132 obo:CL_0000115)
SubClassOf(obo:CL_0000132 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001985))
SubClassOf(obo:CL_0000132 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000133 (neurectodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0000133 "Ectoderm destined to be nervous tissue.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000133 "neurectoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0000133 "neurectodermal cell")
SubClassOf(obo:CL_0000133 obo:CL_0000221)

# Class: obo:CL_0000134 (mesenchymal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMCID:PMC2613570") Annotation(oboInOwl:hasDbXref "PMID:10102814") Annotation(oboInOwl:hasDbXref "PMID:16923606") Annotation(oboInOwl:hasDbXref "PMID:17986482") Annotation(oboInOwl:hasDbXref "PMID:19960544") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells") obo:IAO_0000115 obo:CL_0000134 "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000134 "BTO:0002625")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000134 "BTO:0003298")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000134 "FMA:70546")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000134 "bone marrow stromal cells")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000134 "colony-forming unit-fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11378515") oboInOwl:hasNarrowSynonym obo:CL_0000134 "marrow stromal cells")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000134 "BMSC")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000134 "CFU-F")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11378515") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000134 "MSC")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000134 "mesenchymal precursor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D044982") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000134 "mesenchymal progenitor cells")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000134 "mesenchymal stem cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000134 "mesenchymal stromal cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000134 "mesenchymal stromal cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D044982") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000134 "stem cells, mesenchymal")
AnnotationAssertion(rdfs:comment obo:CL_0000134 "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.")
AnnotationAssertion(rdfs:label obo:CL_0000134 "mesenchymal stem cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0000134 "https://github.com/obophenotype/cell-ontology/issues/474")
SubClassOf(obo:CL_0000134 obo:CL_0000048)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000134 obo:CL_0002320)

# Class: obo:CL_0000135 (circulating fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20303382") Annotation(oboInOwl:hasDbXref "PMID:20305780") Annotation(oboInOwl:hasDbXref "PMID:29286323") Annotation(oboInOwl:hasDbXref "PMID:31473260") Annotation(oboInOwl:hasDbXref "PMID:32084275") Annotation(oboInOwl:hasDbXref "PMID:9177213") Annotation(oboInOwl:hasDbXref "doi:/10.1186/1755-1536-5-S1-S6") obo:IAO_0000115 obo:CL_0000135 "A bone marrow-derived cell that predominantly develops from myeloid lineage-restricted progenitor cells and circulates in peripheral blood, characterized by co-expression of hematopoietic markers CD45 and CD34 along with stromal markers including collagen type I in both humans and mice (Chesney et al., 1997; Blakaj and Bucala, 2012). This spindle-shaped cell exhibits a unique dual identity, functionally bridging immune and stromal compartments with characteristics of both monocytes and fibroblasts. Predominantly arising from circulating monocytes, it migrates to injury sites via chemokine receptors and participates in wound repair through extracellular matrix deposition, cytokine secretion, and antigen presentation via MHC class II. As mesenchymal progenitors, fibrocytes can differentiate into fibroblasts, myofibroblasts, and adipocytes, contributing to both physiological repair and pathological fibrosis (Blakaj and Bucala, 2012).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000135 "FMA:63879")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30826294") oboInOwl:hasNarrowSynonym obo:CL_0000135 "monocyte-derived fibrocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000135 "Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A.")
AnnotationAssertion(rdfs:label obo:CL_0000135 "circulating fibrocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000135 obo:CL_0000499)
SubClassOf(obo:CL_0000135 obo:CL_0011026)
SubClassOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000839))
SubClassOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002495))
SubClassOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042060))
SubClassOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045766))

# Class: obo:CL_0000136 (adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D017667") obo:IAO_0000115 obo:CL_0000136 "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000136 "BTO:0000443")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000136 "CALOHA:TS-0012")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000136 "FMA:63880")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000136 "adipose cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000136 "fat cell")
AnnotationAssertion(rdfs:label obo:CL_0000136 "adipocyte")
SubClassOf(obo:CL_0000136 obo:CL_0000325)
SubClassOf(obo:CL_0000136 obo:CL_0002320)
SubClassOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000137 (osteocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D010011") obo:IAO_0000115 obo:CL_0000137 "A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000137 "bone cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000137 "BTO:0002038")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000137 "CALOHA:TS-1167")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000137 "FMA:66779")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000137 "VSAO:0000124")
AnnotationAssertion(rdfs:comment obo:CL_0000137 "VSAO relationship simplified OBO_REL:integral_part_of VSAO:0000118")
AnnotationAssertion(rdfs:label obo:CL_0000137 "osteocyte")
SubClassOf(obo:CL_0000137 obo:CL_0001035)
SubClassOf(obo:CL_0000137 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002481))
SubClassOf(obo:CL_0000137 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001040))

# Class: obo:CL_0000138 (chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "MESH:D019902") Annotation(oboInOwl:hasDbXref "PMID:32491508") obo:IAO_0000115 obo:CL_0000138 "A skeletogenic cell that secretes a specialized, avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000138 "BTO:0000249")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000138 "CALOHA:TS-0138")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000138 "FMA:66782")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000138 "cartilage cell")
AnnotationAssertion(rdfs:label obo:CL_0000138 "chondrocyte")
SubClassOf(obo:CL_0000138 obo:CL_0000153)
SubClassOf(obo:CL_0000138 obo:CL_0000667)
SubClassOf(obo:CL_0000138 obo:CL_0002320)
SubClassOf(obo:CL_0000138 obo:CL_0007001)
SubClassOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0002418))
SubClassOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000058))

# Class: obo:CL_0000139 (obo:CL_0000139)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000139 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000139 obo:CL_0000059)
AnnotationAssertion(owl:deprecated obo:CL_0000139 "true"^^xsd:boolean)

# Class: obo:CL_0000140 (odontocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0000140 "Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell.")
AnnotationAssertion(rdfs:label obo:CL_0000140 "odontocyte")
SubClassOf(obo:CL_0000140 obo:CL_0002320)
SubClassOf(obo:CL_0000140 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000060))
SubClassOf(obo:CL_0000140 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))
SubClassOf(obo:CL_0000140 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0001751))

# Class: obo:CL_0000141 (cementocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0781733901") obo:IAO_0000115 obo:CL_0000141 "An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000141 "FMA:63003")
AnnotationAssertion(rdfs:comment obo:CL_0000141 "CHECK: wikipedia says that cementocytes no longer produce cementum, but the phenoscape def is: Skeletogenic cell that produces cementum, is part of the odontogenic papilla, and is a transformation of a cementoblast cell (no change to existing def).")
AnnotationAssertion(rdfs:label obo:CL_0000141 "cementocyte")
SubClassOf(obo:CL_0000141 obo:CL_0000137)
SubClassOf(obo:CL_0000141 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0000141 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000061))

# Class: obo:CL_0000142 (hyalocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19073178") obo:IAO_0000115 obo:CL_0000142 "A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000142 "BTO:0004271")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000142 "FMA:70620")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000142 "vitreous cell")
AnnotationAssertion(rdfs:label obo:CL_0000142 "hyalocyte")
SubClassOf(obo:CL_0000142 obo:CL_0000499)

# Class: obo:CL_0000143 (guidepost cell)

AnnotationAssertion(rdfs:label obo:CL_0000143 "guidepost cell")
SubClassOf(obo:CL_0000143 obo:CL_0000130)

# Class: obo:CL_0000144 (obsolete cell by function)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000144 "OBSOLETE: A classification of cells by their primary end goal or behavior.")
AnnotationAssertion(oboInOwl:consider obo:CL_0000144 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000144 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000144 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000144 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its function or behavior. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000144 "obsolete cell by function")
AnnotationAssertion(owl:deprecated obo:CL_0000144 "true"^^xsd:boolean)

# Class: obo:CL_0000145 (professional antigen presenting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000145 "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000145 "APC")
AnnotationAssertion(rdfs:comment obo:CL_0000145 "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000145 "professional antigen presenting cell")
EquivalentClasses(obo:CL_0000145 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504)))
SubClassOf(obo:CL_0000145 obo:CL_0000738)

# Class: obo:CL_0000146 (simple columnar epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000146 "simple columnar epithelial cell")
SubClassOf(obo:CL_0000146 obo:CL_0000075)

# Class: obo:CL_0000147 (pigment cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000147 "A pigment cell is a cell that contains pigment granules.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000147 "VHOG:0001678")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000147 "chromatocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000147 "chromatophore")
AnnotationAssertion(rdfs:label obo:CL_0000147 "pigment cell")
SubClassOf(obo:CL_0000147 obo:CL_0000325)

# Class: obo:CL_0000148 (melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000148 "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000148 "BTO:0000847")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000148 "CALOHA:TS-0613")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000148 "FMA:70545")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000148 "MESH:D008544")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000148 "VHOG:0001679")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000148 "melanophore")
AnnotationAssertion(rdfs:label obo:CL_0000148 "melanocyte")
EquivalentClasses(obo:CL_0000148 ObjectIntersectionOf(obo:CL_0000147 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042470) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000541)))

# Class: obo:CL_0000149 (visual pigment cell)

AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000149 "pigment cell")
AnnotationAssertion(rdfs:label obo:CL_0000149 "visual pigment cell")
SubClassOf(obo:CL_0000149 obo:CL_0000147)

# Class: obo:CL_0000150 (glandular secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ORCID:0000-0002-7073-9172") obo:IAO_0000115 obo:CL_0000150 "An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000150 "CALOHA:TS-2085")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000150 "FMA:86494")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000150 "glandular epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0000150 "glandular secretory epithelial cell")
EquivalentClasses(obo:CL_0000150 ObjectIntersectionOf(obo:CL_0000066 obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002530)))

# Class: obo:CL_0000151 (secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000151 "A cell that specializes in controlled release of one or more substances.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000151 "BTO:0003659")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000151 "FMA:86916")
AnnotationAssertion(rdfs:label obo:CL_0000151 "secretory cell")
EquivalentClasses(obo:CL_0000151 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940)))

# Class: obo:CL_0000152 (exocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0198547684") obo:IAO_0000115 obo:CL_0000152 "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000152 "FMA:16014")
AnnotationAssertion(rdfs:label obo:CL_0000152 "exocrine cell")
EquivalentClasses(obo:CL_0000152 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002365)))
SubClassOf(obo:CL_0000152 obo:CL_0000151)

# Class: obo:CL_0000153 (glycosaminoglycan secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000153 "A cell that secretes glycosaminoglycans.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000153 "GAG secreting cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000153 "hyaluronic acid secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000153 "glycosaminoglycan secreting cell")
SubClassOf(obo:CL_0000153 obo:CL_0000327)
SubClassOf(obo:CL_0000153 obo:CL_0000447)

# Class: obo:CL_0000154 (protein secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000154 "protein secreting cell")
EquivalentClasses(obo:CL_0000154 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009306)))

# Class: obo:CL_0000155 (peptic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:21907708") Annotation(oboInOwl:hasDbXref "PMID:30571046") Annotation(oboInOwl:hasDbXref "Wikipedia:Gastric_chief_cell") obo:IAO_0000115 obo:CL_0000155 "An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by a basally located nucleus, abundant rough endoplasmic reticulum, and large apical secretory granules. It produces and secretes pepsinogen, the inactive precursor of the digestive enzyme pepsin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000155 "FMA:62902")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000155 "chief cell of stomach")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Chief_cell") oboInOwl:hasExactSynonym obo:CL_0000155 "gastric chief cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000155 "pepsinogen secreting cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Chief_cell") oboInOwl:hasExactSynonym obo:CL_0000155 "zymogenic cell")
AnnotationAssertion(rdfs:label obo:CL_0000155 "peptic cell")
SubClassOf(obo:CL_0000155 obo:CL_0000154)
SubClassOf(obo:CL_0000155 obo:CL_0002178)
SubClassOf(obo:CL_0000155 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))
SubClassOf(obo:CL_0000155 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010038))

# Class: obo:CL_0000156 (obsolete antibody secreting cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000156 "OBSOLETE: A cell of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B cells, can be defined, based on the different classes of immunoglobulins that they synthesize.")
AnnotationAssertion(rdfs:comment obo:CL_0000156 "Consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000156 "obsolete antibody secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000156 "true"^^xsd:boolean)

# Class: obo:CL_0000157 (surfactant secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000157 "A cell that specializes in secretion of surfactant in the alveoli of the lung.")
AnnotationAssertion(rdfs:label obo:CL_0000157 "surfactant secreting cell")
EquivalentClasses(obo:CL_0000157 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043129)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000157 obo:CL_0000151)

# Class: obo:CL_0000158 (club cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1183/09031936.00146609") Annotation(oboInOwl:hasDbXref "DOI:10.1378/chest.12-2762") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:28128362") Annotation(oboInOwl:hasDbXref "PMID:29874100") Annotation(oboInOwl:hasDbXref "PMID:7905712") obo:IAO_0000115 obo:CL_0000158 "A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000158 "BTO:0004811")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000158 "FMA:14119")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000158 "Clara cell")
AnnotationAssertion(rdfs:label obo:CL_0000158 "club cell")
SubClassOf(obo:CL_0000158 obo:CL_0002202)
SubClassOf(obo:CL_0000158 obo:CL_0011026)
SubClassOf(obo:CL_0000158 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0005902))
SubClassOf(obo:CL_0000158 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940))
SubClassOf(obo:CL_0000158 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043129))

# Class: obo:CL_0000159 (seromucus secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000159 "seromucus secreting cell")
SubClassOf(obo:CL_0000159 obo:CL_0000151)

# Class: obo:CL_0000160 (goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D020397") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Goblet_cell") obo:IAO_0000115 obo:CL_0000160 "A specialized, columnar, mucus secreting epithelial cell shaped like a flask or goblet. A narrow basal end contains the nucleus while the apical end is swollen by the accumulation of mucus laden secretory granules.  Short microvilli project from the apical plasma membrane.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000160 "BTO:0001540")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000160 "FMA:13148")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000160 "http://en.wikipedia.org/wiki/Goblet_cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000160 "chalice cell")
AnnotationAssertion(rdfs:label obo:CL_0000160 "goblet cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://cnx.org/content/col11496/1.6/>) Annotation(oboInOwl:hasDbXref <https://commons.wikimedia.org/w/index.php?curid=30131227>) foaf:depiction obo:CL_0000160 "https://upload.wikimedia.org/wikipedia/commons/thumb/c/c4/404_Goblet_Cell_new.jpg/800px-404_Goblet_Cell_new.jpg")
SubClassOf(obo:CL_0000160 obo:CL_0000066)
SubClassOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))
SubClassOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0098594))
SubClassOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_0000161 (obsolete acid secreting cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000161 <https://github.com/obophenotype/cell-ontology/issues/427>)
AnnotationAssertion(oboInOwl:consider obo:CL_0000161 obo:CL_0000162)
AnnotationAssertion(rdfs:label obo:CL_0000161 "obsolete acid secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000161 "true"^^xsd:boolean)

# Class: obo:CL_0000162 (parietal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:31613538") Annotation(oboInOwl:hasDbXref "PMID:31670611") obo:IAO_0000115 obo:CL_0000162 "An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by its pyramidal shape, abundant mitochondria, and a complex network of secretory canaliculi lined with microvilli. It secretes hydrochloric acid into the stomach lumen and produces intrinsic factor, essential for vitamin B12 absorption.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000162 "BTO:0001780")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000162 "FMA:62901")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29263912") oboInOwl:hasExactSynonym obo:CL_0000162 "gastric parietal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Parietal_cell") oboInOwl:hasExactSynonym obo:CL_0000162 "oxyntic cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29263912") Annotation(oboInOwl:hasDbXref "PMID:31613538") rdfs:comment obo:CL_0000162 "Parietal cells have dynamic, actin-supported microvilli that increase in number during active secretion, playing a crucial role in secreting hydrochloric acid and intrinsic factor. The structure and regulation of these microvilli are influenced by proteins such as ASAP3, which modulates Arf6 activity and actin assembly, thereby controlling microvilli formation and parietal cell function.")
AnnotationAssertion(rdfs:label obo:CL_0000162 "parietal cell")
SubClassOf(obo:CL_0000162 obo:CL_0000151)
SubClassOf(obo:CL_0000162 obo:CL_0002178)
SubClassOf(obo:CL_0000162 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))
SubClassOf(obo:CL_0000162 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010038))
SubClassOf(obo:CL_0000162 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))
SubClassOf(obo:CL_0000162 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001696))

# Class: obo:CL_0000163 (endocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D055098") obo:IAO_0000115 obo:CL_0000163 "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000163 "FMA:83809")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000163 "endocrinocyte")
AnnotationAssertion(rdfs:label obo:CL_0000163 "endocrine cell")
EquivalentClasses(obo:CL_0000163 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0046879 ObjectSomeValuesFrom(obo:RO_0002339 obo:UBERON_0001009)))))
SubClassOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000949))

# Class: obo:CL_0000164 (enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000164 "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "BTO:0003865")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "FMA:62930")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "MESH:D019858")
AnnotationAssertion(rdfs:label obo:CL_0000164 "enteroendocrine cell")
SubClassOf(obo:CL_0000164 obo:CL_0000066)
SubClassOf(obo:CL_0000164 obo:CL_0000163)

# Class: obo:CL_0000165 (neuroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D055099") obo:IAO_0000115 obo:CL_0000165 "A neuron that is capable of some hormone secretion in response to neuronal signals.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000165 "BTO:0002691")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000165 "FMA:83810")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000165 "neurosecretory cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000165 "neurosecretory neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5342440") Annotation(oboInOwl:hasDbXref "https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073") rdfs:comment obo:CL_0000165 "The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. 

The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.")
AnnotationAssertion(rdfs:label obo:CL_0000165 "neuroendocrine cell")
EquivalentClasses(obo:CL_0000165 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046879)))
SubClassOf(obo:CL_0000165 obo:CL_0000163)
SubClassOf(obo:CL_0000165 obo:CL_0000393)
SubClassOf(obo:CL_0000165 obo:CL_0000527)
SubClassOf(obo:CL_0000165 obo:CL_0000710)

# Class: obo:CL_0000166 (chromaffin cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D019439") obo:IAO_0000115 obo:CL_0000166 "A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000166 "BTO:0000259")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000166 "FMA:69263")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000166 "phaeochromocyte")
AnnotationAssertion(rdfs:label obo:CL_0000166 "chromaffin cell")
SubClassOf(obo:CL_0000166 obo:CL_0000568)
SubClassOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0000167 (peptide hormone secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000167 "peptide hormone secreting cell")
EquivalentClasses(obo:CL_0000167 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030072)))

# Class: obo:CL_0000168 (insulin secreting cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000168 "BTO:0000783")
AnnotationAssertion(rdfs:label obo:CL_0000168 "insulin secreting cell")
EquivalentClasses(obo:CL_0000168 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030073)))

# Class: obo:CL_0000169 (type B pancreatic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Pancreatic_b_cell") obo:IAO_0000115 obo:CL_0000169 "A cell that secretes insulin and is located towards the center of the islets of Langerhans.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0009102") oboInOwl:hasBroadSynonym obo:CL_0000169 "beta cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000169 "BTO:0000783")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000169 "EV:0200009")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000169 "FMA:70586")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000169 "MA:0002419")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000169 "ncithesaurus:Beta_Cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "B-cell of pancreatic islet")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "beta cell of pancreatic islet")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "insulin-secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000169 "pancreatic B cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "pancreatic B-cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "pancreatic beta cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MA:0002419") oboInOwl:hasExactSynonym obo:CL_0000169 "pancreatic islet core")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70586") oboInOwl:hasExactSynonym obo:CL_0000169 "type B enteroendocrine cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MA:0002419") oboInOwl:hasRelatedSynonym obo:CL_0000169 "beta cell islet")
AnnotationAssertion(rdfs:comment obo:CL_0000169 "Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.")
AnnotationAssertion(rdfs:label obo:CL_0000169 "type B pancreatic cell")
EquivalentClasses(obo:CL_0000169 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030073)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000169 obo:CL_0000164)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000169 obo:CL_0000168)
SubClassOf(obo:CL_0000169 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002351))

# Class: obo:CL_0000170 (glucagon secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000170 "A cell that secretes glucagon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000170 "FMA:84045")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000170 "glucagon-secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000170 "glucagon secreting cell")
EquivalentClasses(obo:CL_0000170 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070091)))

# Class: obo:CL_0000171 (pancreatic A cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000171 "A type A enteroendocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000171 "BTO:0000990")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000171 "FMA:70585")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000171 "MESH:D050416")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000171 "alpha cell of islet of Langerhans")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000171 "pancreatic alpha cell")
AnnotationAssertion(rdfs:label obo:CL_0000171 "pancreatic A cell")
EquivalentClasses(obo:CL_0000171 ObjectIntersectionOf(obo:CL_0002067 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006)))
SubClassOf(obo:CL_0000171 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002351))
SubClassOf(obo:CL_0000171 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070091))

# Class: obo:CL_0000172 (somatostatin secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000172 "somatostatin secreting cell")
EquivalentClasses(obo:CL_0000172 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070253)))

# Class: obo:CL_0000173 (pancreatic D cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0517223651") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000173 "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000173 "BTO:0000803")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000173 "FMA:70587")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "D-cell of pancreatic islet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "delta cell of islet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "delta cell of pancreatic islet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "pancreatic D-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "pancreatic delta cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000173 "somatostatin-secreting pancreatic cell")
AnnotationAssertion(rdfs:label obo:CL_0000173 "pancreatic D cell")
EquivalentClasses(obo:CL_0000173 ObjectIntersectionOf(obo:CL_0000502 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))
SubClassOf(obo:CL_0000173 obo:CL_0000502)
SubClassOf(obo:CL_0000173 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006))
SubClassOf(obo:CL_0000173 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002351))

# Class: obo:CL_0000174 (steroid hormone secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000174 "steroid hormone secreting cell")
EquivalentClasses(obo:CL_0000174 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035929)))

# Class: obo:CL_0000175 (luteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D008184") Annotation(oboInOwl:hasDbXref "PMID:31849844") obo:IAO_0000115 obo:CL_0000175 "A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000175 "BTO:0003939")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000175 "FMA:18688")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16790079") oboInOwl:hasExactSynonym obo:CL_0000175 "corpus luteum cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000175 "lutein cell")
AnnotationAssertion(rdfs:label obo:CL_0000175 "luteal cell")
SubClassOf(obo:CL_0000175 obo:CL_0000174)
SubClassOf(obo:CL_0000175 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002512))
SubClassOf(obo:CL_0000175 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042701))

# Class: obo:CL_0000176 (ecdysteroid secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000176 "ecdysteroid secreting cell")
EquivalentClasses(obo:CL_0000176 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045457)))

# Class: obo:CL_0000177 (testosterone secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000177 "testosterone secreting cell")
EquivalentClasses(obo:CL_0000177 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035936)))

# Class: obo:CL_0000178 (Leydig cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12050120") obo:IAO_0000115 obo:CL_0000178 "A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000178 "interstitial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000178 "BTO:0000755")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000178 "CALOHA:TS-1150")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000178 "EMAPA:29655")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000178 "FMA:72297")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000178 "MESH:D007985")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000178 "interstitial cell of Leydig")
AnnotationAssertion(rdfs:comment obo:CL_0000178 "Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated")
AnnotationAssertion(rdfs:label obo:CL_0000178 "Leydig cell")
SubClassOf(obo:CL_0000178 obo:CL_0000177)
SubClassOf(obo:CL_0000178 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005212))
SubClassOf(obo:CL_0000178 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0009091))

# Class: obo:CL_0000179 (progesterone secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000179 "progesterone secreting cell")
EquivalentClasses(obo:CL_0000179 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042701)))

# Class: obo:CL_0000180 (estradiol secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000180 "A steroid hormone secreting cell that secretes estradiol.")
AnnotationAssertion(rdfs:label obo:CL_0000180 "estradiol secreting cell")
EquivalentClasses(obo:CL_0000180 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035938)))

# Class: obo:CL_0000181 (obsolete metabolising cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000181 "A cell whose primary function is intermediary metabolism.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000181 <https://github.com/obophenotype/cell-ontology/issues/720>)
AnnotationAssertion(rdfs:comment obo:CL_0000181 "Removing this grouping class, because the groupings are incomplete and too hard to maintain.")
AnnotationAssertion(rdfs:label obo:CL_0000181 "obsolete metabolising cell")
AnnotationAssertion(owl:deprecated obo:CL_0000181 "true"^^xsd:boolean)

# Class: obo:CL_0000182 (hepatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "MESH:D022781") Annotation(oboInOwl:hasDbXref "PMID:19717280") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Hepatocyte") obo:IAO_0000115 obo:CL_0000182 "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000182 "BTO:0000575")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000182 "CALOHA:TS-0454")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000182 "FMA:14515")
AnnotationAssertion(rdfs:comment obo:CL_0000182 "Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000182 "hepatocyte")
SubClassOf(obo:CL_0000182 obo:CL_0000066)
SubClassOf(obo:CL_0000182 obo:CL_0000417)
SubClassOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107))
SubClassOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005026))
SubClassOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006699))
SubClassOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0098754))

# Class: obo:CL_0000183 (contractile cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000183 "A cell whose primary function is to shorten.")
AnnotationAssertion(rdfs:label obo:CL_0000183 "contractile cell")
SubClassOf(obo:CL_0000183 obo:CL_0000000)

# Class: obo:CL_0000184 (obo:CL_0000184)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000184 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000184 obo:CL_0000669)
AnnotationAssertion(owl:deprecated obo:CL_0000184 "true"^^xsd:boolean)

# Class: obo:CL_0000185 (myoepithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000185 "Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000185 "BTO:0002309")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000185 "CALOHA:TS-2379")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000185 "FMA:67799")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000185 "basket epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000185 "myoepitheliocyte")
AnnotationAssertion(rdfs:label obo:CL_0000185 "myoepithelial cell")
SubClassOf(obo:CL_0000185 obo:CL_0000075)
SubClassOf(obo:CL_0000185 obo:CL_0000183)

# Class: obo:CL_0000186 (myofibroblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D058628") Annotation(oboInOwl:hasDbXref "PMID:19800625") Annotation(oboInOwl:hasDbXref "PMID:20630469") Annotation(oboInOwl:hasDbXref "PMID:22387320") obo:IAO_0000115 obo:CL_0000186 "An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8731193") oboInOwl:hasExactSynonym obo:CL_0000186 "MFB")
AnnotationAssertion(rdfs:comment obo:CL_0000186 "Myofibroblasts are alpha-SMA-positive, CD34-negative, CD45-negative. They are reportedly capable of secreting IL-1beta, IL-6, and TNF-alpha.")
AnnotationAssertion(rdfs:label obo:CL_0000186 "myofibroblast cell")
SubClassOf(obo:CL_0000186 obo:CL_0000183)
SubClassOf(obo:CL_0000186 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002384))

# Class: obo:CL_0000187 (muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D032342") obo:IAO_0000115 obo:CL_0000187 "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000187 "BTO:0000888")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000187 "BTO:0000902")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000187 "CALOHA:TS-2032")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000187 "FMA:67328")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000187 "WBbt:0003675")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000187 "muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000187 "myocyte")
AnnotationAssertion(rdfs:label obo:CL_0000187 "muscle cell")
AnnotationAssertion(foaf:depiction obo:CL_0000187 "https://www.swissbiopics.org/api/image/Muscle_cells.svg"^^xsd:anyURI)
SubClassOf(obo:CL_0000187 obo:CL_0000183)
SubClassOf(obo:CL_0000187 obo:CL_0000393)
SubClassOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000056))

# Class: obo:CL_0000188 (cell of skeletal muscle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000188 "A somatic cell located in skeletal muscle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000188 "BTO:0004392")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000188 "CALOHA:TS-2158")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000188 "FMA:9727")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000188 "skeletal muscle cell")
AnnotationAssertion(rdfs:label obo:CL_0000188 "cell of skeletal muscle")
EquivalentClasses(obo:CL_0000188 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134)))

# Class: obo:CL_0000189 (slow muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0000189 "A muscle cell that develops tension more slowly than a fast-twitch fiber.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0815316208") oboInOwl:hasRelatedSynonym obo:CL_0000189 "slow muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0000189 "slow muscle cell")
SubClassOf(obo:CL_0000189 obo:CL_0008046)
SubClassOf(obo:CL_0000189 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000857))

# Class: obo:CL_0000190 (fast muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0000190 "A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000190 "glycolytic muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0000190 "fast muscle cell")
SubClassOf(obo:CL_0000190 obo:CL_0008046)
SubClassOf(obo:CL_0000190 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000858))

# Class: obo:CL_0000191 (obo:CL_0000191)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000191 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000191 obo:CL_0000192)
AnnotationAssertion(owl:deprecated obo:CL_0000191 "true"^^xsd:boolean)

# Class: obo:CL_0000192 (smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D032389") Annotation(oboInOwl:hasDbXref "PMID:9315361") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Smooth_muscle_cell") obo:IAO_0000115 obo:CL_0000192 "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000192 "non-striated muscle cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000192 "BTO:0004576")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000192 "CALOHA:TS-2159")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000192 "FMA:14072")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9315361") oboInOwl:hasExactSynonym obo:CL_0000192 "SMCs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D032389") oboInOwl:hasExactSynonym obo:CL_0000192 "myocytes, smooth muscle")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000192 "smooth muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0000192 "smooth muscle cell")
SubClassOf(obo:CL_0000192 obo:CL_0008000)
SubClassOf(obo:CL_0000192 obo:CL_0008007)
SubClassOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000514))

# Class: obo:CL_0000193 (cardiac muscle cell (sensu Arthopoda))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D032383") obo:IAO_0000115 obo:CL_0000193 "A striated muscle cell of an arthropod heart that participates in heart contraction.")
AnnotationAssertion(rdfs:label obo:CL_0000193 "cardiac muscle cell (sensu Arthopoda)")
EquivalentClasses(obo:CL_0000193 ObjectIntersectionOf(obo:CL_0000746 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000465)))

# Class: obo:CL_0000194 (obsolete nodal cardiac cell)

AnnotationAssertion(rdfs:comment obo:CL_0000194 "Consider CL:0002072.")
AnnotationAssertion(rdfs:label obo:CL_0000194 "obsolete nodal cardiac cell")
AnnotationAssertion(owl:deprecated obo:CL_0000194 "true"^^xsd:boolean)

# Class: obo:CL_0000195 (obsolete Purkinje fiber)

AnnotationAssertion(rdfs:label obo:CL_0000195 "obsolete Purkinje fiber")
AnnotationAssertion(owl:deprecated obo:CL_0000195 "true"^^xsd:boolean)

# Class: obo:CL_0000196 (insect flight muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.2142/biophysics.7.21") obo:IAO_0000115 obo:CL_0000196 "A muscle cell that is involved in the mechanism of insect flight. This encompasses both, cells that power flight and cells that control flight.")
AnnotationAssertion(rdfs:label obo:CL_0000196 "insect flight muscle cell")
SubClassOf(obo:CL_0000196 obo:CL_0008004)
SubClassOf(obo:CL_0000196 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017))
SubClassOf(obo:CL_0000196 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908))
SubClassOf(obo:CL_0000196 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478))

# Class: obo:CL_0000197 (sensory receptor cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000197 "A cell that is capable of detection of a stimulus involved in sensory perception.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000197 "MESH:D011984")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000197 "receptor cell")
AnnotationAssertion(rdfs:label obo:CL_0000197 "sensory receptor cell")
EquivalentClasses(obo:CL_0000197 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001032) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))

# Class: obo:CL_0000198 (pain receptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009619") obo:IAO_0000115 obo:CL_0000198 "The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings.")
AnnotationAssertion(Annotation(rdfs:seeAlso "https://meshb.nlm.nih.gov/record/ui?ui=D009619"^^xsd:anyURI) oboInOwl:hasExactSynonym obo:CL_0000198 "nociceptor")
AnnotationAssertion(Annotation(rdfs:seeAlso "https://www.thefreedictionary.com/nocireceptor"^^xsd:anyURI) oboInOwl:hasExactSynonym obo:CL_0000198 "nocireceptor")
AnnotationAssertion(rdfs:comment obo:CL_0000198 "Editor note: request detection of stimulus involved in sensory perception of pain; add develops_from relationship")
AnnotationAssertion(rdfs:label obo:CL_0000198 "pain receptor cell")
SubClassOf(obo:CL_0000198 obo:CL_0000006)

# Class: obo:CL_0000199 (mechanoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D008465") obo:IAO_0000115 obo:CL_0000199 "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0000972") oboInOwl:hasRelatedSynonym obo:CL_0000199 "mechanoreceptor")
AnnotationAssertion(rdfs:label obo:CL_0000199 "mechanoreceptor cell")
EquivalentClasses(obo:CL_0000199 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050974)))

# Class: obo:CL_0000200 (touch receptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000200 "touch receptor cell")
EquivalentClasses(obo:CL_0000200 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050976)))

# Class: obo:CL_0000201 (obo:CL_0000201)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000201 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000201 obo:CL_0000202)
AnnotationAssertion(owl:deprecated obo:CL_0000201 "true"^^xsd:boolean)

# Class: obo:CL_0000202 (auditory hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D006198") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Hair_cell&oldid=1045345915") obo:IAO_0000115 obo:CL_0000202 "A mechanoreceptor cell of the auditory or vestibular system that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000202 "auditory receptor cell")
AnnotationAssertion(rdfs:comment obo:CL_0000202 "In mammals these cells are located in the organ of Corti.")
AnnotationAssertion(rdfs:label obo:CL_0000202 "auditory hair cell")
SubClassOf(obo:CL_0000202 obo:CL_0000855)
SubClassOf(obo:CL_0000202 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050910))

# Class: obo:CL_0000203 (gravity sensitive cell)

AnnotationAssertion(rdfs:label obo:CL_0000203 "gravity sensitive cell")
EquivalentClasses(obo:CL_0000203 ObjectIntersectionOf(obo:CL_0000006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070999)))

# Class: obo:CL_0000204 (acceleration receptive cell)

AnnotationAssertion(rdfs:label obo:CL_0000204 "acceleration receptive cell")
SubClassOf(obo:CL_0000204 obo:CL_0000006)

# Class: obo:CL_0000205 (thermoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D013823") Annotation(oboInOwl:hasDbXref "MP:0000971") obo:IAO_0000115 obo:CL_0000205 "A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain.")
AnnotationAssertion(rdfs:label obo:CL_0000205 "thermoreceptor cell")
EquivalentClasses(obo:CL_0000205 ObjectIntersectionOf(obo:CL_0000006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050960)))

# Class: obo:CL_0000206 (chemoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D002628") obo:IAO_0000115 obo:CL_0000206 "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.")
AnnotationAssertion(rdfs:label obo:CL_0000206 "chemoreceptor cell")
EquivalentClasses(obo:CL_0000206 ObjectIntersectionOf(obo:CL_0000197 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050907)))

# Class: obo:CL_0000207 (olfactory receptor cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000207 "BTO:0004185")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000207 "FMA:67860")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000207 "MESH:D018034")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000207 "Wikipedia:Olfactory_receptor_neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000207 "Schultze's cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000207 "odorant receptor cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000207 "olfactory receptor neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000207 "olfactory sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0000207 "olfactory receptor cell")
EquivalentClasses(obo:CL_0000207 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050911)))
SubClassOf(obo:CL_0000207 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005725))

# Class: obo:CL_0000208 (pH receptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000208 "pH receptor cell")
SubClassOf(obo:CL_0000208 obo:CL_0000206)

# Class: obo:CL_0000209 (taste receptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000209 "A specialized cell involved in gustatory sensory perception.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000209 "FMA:67910")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000209 "taste bud cell")
AnnotationAssertion(rdfs:label obo:CL_0000209 "taste receptor cell")
EquivalentClasses(obo:CL_0000209 ObjectIntersectionOf(obo:CL_0000206 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050912)))
SubClassOf(obo:CL_0000209 obo:CL_0000098)
SubClassOf(obo:CL_0000209 obo:CL_0002076)

# Class: obo:CL_0000210 (photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D010786") obo:IAO_0000115 obo:CL_0000210 "A cell specialized in detecting light stimuli that are involved in visual perception.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000210 "BTO:0001060")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000210 "CALOHA:TS-0868")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000210 "FMA:86740")
AnnotationAssertion(rdfs:label obo:CL_0000210 "photoreceptor cell")
AnnotationAssertion(foaf:depiction obo:CL_0000210 "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI)
EquivalentClasses(obo:CL_0000210 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050908)))
SubClassOf(obo:CL_0000210 obo:CL_0008028)

# Class: obo:CL_0000211 (electrically active cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000211 "A cell whose function is determined by the generation or the reception of an electric signal.")
AnnotationAssertion(rdfs:label obo:CL_0000211 "electrically active cell")
SubClassOf(obo:CL_0000211 obo:CL_0000000)

# Class: obo:CL_0000212 (obsolete absorptive cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0000212 "OBSOLETE. A cell that takes up and metabolizes substances.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000212 <https://github.com/obophenotype/cell-ontology/issues/2271>)
AnnotationAssertion(rdfs:comment obo:CL_0000212 "It has no child terms. Consider using 'gut absorptive cell'.")
AnnotationAssertion(rdfs:label obo:CL_0000212 "obsolete absorptive cell")
AnnotationAssertion(owl:deprecated obo:CL_0000212 "true"^^xsd:boolean)

# Class: obo:CL_0000213 (obsolete lining cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000213 "OBSOLETE. A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000213 <https://github.com/obophenotype/cell-ontology/issues/3014>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000213 "boundary cell")
AnnotationAssertion(rdfs:comment obo:CL_0000213 "Obsoleted term because redundant")
AnnotationAssertion(rdfs:label obo:CL_0000213 "obsolete lining cell")
AnnotationAssertion(owl:deprecated obo:CL_0000213 "true"^^xsd:boolean)

# Class: obo:CL_0000214 (synovial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000214 "A cell located in the synovial joint.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000214 "CALOHA:TS-0995")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000214 "synoviocyte")
AnnotationAssertion(rdfs:label obo:CL_0000214 "synovial cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000214 obo:CL_0002078)
SubClassOf(obo:CL_0000214 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002217))

# Class: obo:CL_0000215 (obsolete barrier cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000215 "OBSOLETE. A cell whose primary function is to prevent the transport of stuff across compartments.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000215 <https://github.com/obophenotype/cell-ontology/issues/3012>)
AnnotationAssertion(rdfs:comment obo:CL_0000215 "Not needed term")
AnnotationAssertion(rdfs:label obo:CL_0000215 "obsolete barrier cell")
AnnotationAssertion(owl:deprecated obo:CL_0000215 "true"^^xsd:boolean)

# Class: obo:CL_0000216 (Sertoli cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D012708") obo:IAO_0000115 obo:CL_0000216 "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000216 "BTO:0001238")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000216 "CALOHA:TS-0922")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000216 "FMA:72298")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000216 "VHOG:0001348")
AnnotationAssertion(rdfs:label obo:CL_0000216 "Sertoli cell")
EquivalentClasses(obo:CL_0000216 ObjectIntersectionOf(obo:CL_0000630 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001343)))
SubClassOf(obo:CL_0000216 obo:CL_0000511)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000216 obo:CL_0000630)
SubClassOf(obo:CL_0000216 obo:CL_0002625)

# Class: obo:CL_0000217 (obsolete insulating cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000217 <https://github.com/obophenotype/cell-ontology/issues/3013>)
AnnotationAssertion(rdfs:comment obo:CL_0000217 "obsoleted because the term is not needed")
AnnotationAssertion(rdfs:label obo:CL_0000217 "obsolete insulating cell")
AnnotationAssertion(owl:deprecated obo:CL_0000217 "true"^^xsd:boolean)

# Class: obo:CL_0000218 (myelinating Schwann cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D012583") obo:IAO_0000115 obo:CL_0000218 "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000218 "Schwann cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000218 "peripheral neuroglial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000218 "CALOHA:TS-0898")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000218 "FMA:62121")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000218 "neurilemmal cell")
AnnotationAssertion(rdfs:label obo:CL_0000218 "myelinating Schwann cell")
SubClassOf(obo:CL_0000218 obo:CL_0002573)
SubClassOf(obo:CL_0000218 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043209))
SubClassOf(obo:CL_0000218 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002377))

# Class: obo:CL_0000219 (motile cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000219 "A cell that moves by its own activities.")
AnnotationAssertion(rdfs:label obo:CL_0000219 "motile cell")
EquivalentClasses(obo:CL_0000219 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048870)))

# Class: obo:CL_0000220 (obsolete cell by lineage)

AnnotationAssertion(oboInOwl:consider obo:CL_0000220 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000220 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000220 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000220 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell in a multicellular organiam, apart from a zygote, can potentially be classified by its lineage. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000220 "obsolete cell by lineage")
AnnotationAssertion(owl:deprecated obo:CL_0000220 "true"^^xsd:boolean)

# Class: obo:CL_0000221 (ectodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D004475") obo:IAO_0000115 obo:CL_0000221 "A cell of the outer of the three germ layers of the embryo.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000221 "FMA:72549")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000221 "ectoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0000221 "ectodermal cell")
SubClassOf(obo:CL_0000221 obo:CL_0002321)
SubClassOf(obo:CL_0000221 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000924))

# Class: obo:CL_0000222 (mesodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D008648") obo:IAO_0000115 obo:CL_0000222 "A cell of the middle germ layer of the embryo.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000222 "FMA:72554")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000222 "mesoblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000222 "mesoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0000222 "mesodermal cell")
SubClassOf(obo:CL_0000222 obo:CL_0002321)
SubClassOf(obo:CL_0000222 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000926))

# Class: obo:CL_0000223 (endodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D004707") obo:IAO_0000115 obo:CL_0000223 "A cell of the inner of the three germ layers of the embryo.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000223 "FMA:72555")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000223 "endoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0000223 "endodermal cell")
SubClassOf(obo:CL_0000223 obo:CL_0002321)
SubClassOf(obo:CL_0000223 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000925))

# Class: obo:CL_0000224 (obsolete cell by nuclear number)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000224 "OBSOLETE: A classification of cells by the number of their nuclei.")
AnnotationAssertion(oboInOwl:consider obo:CL_0000224 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000224 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000224 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000224 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell can be classified by its nuclear number (note that this term was previously used as a parent class of enucleate cell). If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000224 "obsolete cell by nuclear number")
AnnotationAssertion(owl:deprecated obo:CL_0000224 "true"^^xsd:boolean)

# Class: obo:CL_0000225 (anucleate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000225 "A cell that lacks a nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000225 "FMA:68647")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000225 "non-nucleated cell")
AnnotationAssertion(rdfs:label obo:CL_0000225 "anucleate cell")
EquivalentClasses(obo:CL_0000225 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405)))
DisjointClasses(obo:CL_0000225 obo:CL_0002242)

# Class: obo:CL_0000226 (single nucleate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000226 "A cell with a single nucleus.")
AnnotationAssertion(rdfs:label obo:CL_0000226 "single nucleate cell")
EquivalentClasses(obo:CL_0000226 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))

# Class: obo:CL_0000227 (binucleate cell)

AnnotationAssertion(rdfs:label obo:CL_0000227 "binucleate cell")
EquivalentClasses(obo:CL_0000227 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001406)))

# Class: obo:CL_0000228 (multinucleate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "Wikipedia:Multinucleate") obo:IAO_0000115 obo:CL_0000228 "A cell with more than one nucleus.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Multinucleate") oboInOwl:hasExactSynonym obo:CL_0000228 "multinucleated cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Multinucleate") oboInOwl:hasExactSynonym obo:CL_0000228 "polynuclear cells")
AnnotationAssertion(rdfs:label obo:CL_0000228 "multinucleate cell")
EquivalentClasses(obo:CL_0000228 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908)))

# Class: obo:CL_0000229 (obsolete lymphoblast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000229 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000229 "Refers to an activated mature lymphocyte phenotype rather than a distinct cell type; consider using 'lymphocyte ; CL:0000542' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000229 "obsolete lymphoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000229 "true"^^xsd:boolean)

# Class: obo:CL_0000230 (obsolete T lymphoblast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000230 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000230 "Refers to an activated mature T lymphocyte phenotype rather than a distinct cell type; consider using 'T cell ; CL:0000084' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000230 "obsolete T lymphoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000230 "true"^^xsd:boolean)

# Class: obo:CL_0000231 (obsolete B lymphoblast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000231 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000231 "Refers to an activated mature B lymphocyte phenotype rather than a distinct cell type; consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000231 "obsolete B lymphoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000231 "true"^^xsd:boolean)

# Class: obo:CL_0000232 (erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D004912") obo:IAO_0000115 obo:CL_0000232 "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000232 "BTO:0000424")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000232 "CALOHA:TS-0290")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000232 "FMA:81100")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000232 "RBC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000232 "red blood cell")
AnnotationAssertion(rdfs:label obo:CL_0000232 "erythrocyte")
EquivalentClasses(obo:CL_0000232 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005840) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002039) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015671)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000232 obo:CL_0000764)
SubClassOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000558))

# Class: obo:CL_0000233 (platelet)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D001792") Annotation(oboInOwl:hasDbXref "PMID:11110672") Annotation(oboInOwl:hasDbXref "PMID:16987572") Annotation(oboInOwl:hasDbXref "PMID:17204662") Annotation(oboInOwl:hasDbXref "PMID:17479180") Annotation(oboInOwl:hasDbXref "PMID:20414831") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Platelet") obo:IAO_0000115 obo:CL_0000233 "A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000233 "BTO:0000132")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000233 "CALOHA:TS-0803")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000233 "FMA:62851")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000233 "anucleate thrombocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000233 "blood platelet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000233 "enucleate thrombocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000233 "Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF.")
AnnotationAssertion(rdfs:label obo:CL_0000233 "platelet")
SubClassOf(obo:CL_0000233 obo:CL_0000081)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000233 obo:CL_0000763)
SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405))
SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001874))
SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000556))
SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820))
SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0007596))

# Class: obo:CL_0000234 (phagocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000234 "Any cell capable of ingesting particulate matter via phagocytosis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "BTO:0001044")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "FMA:83806")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "MESH:D010586")
AnnotationAssertion(rdfs:label obo:CL_0000234 "phagocyte")
EquivalentClasses(obo:CL_0000234 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909)))
SubClassOf(obo:CL_0000234 obo:CL_0000219)
SubClassOf(obo:CL_0000234 obo:CL_0000325)

# Class: obo:CL_0000235 (macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16213494") Annotation(oboInOwl:hasDbXref "PMID:1919437") obo:IAO_0000115 obo:CL_0000235 "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "BTO:0000801")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "CALOHA:TS-0587")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "FMA:63261")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "FMA:83585")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "MESH:D008264")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000235 "histiocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000235 "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000235 "macrophage")
EquivalentClasses(obo:CL_0000235 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031268)))
SubClassOf(obo:CL_0000235 obo:CL_0000113)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000235 obo:CL_0000766)
SubClassOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))

# Class: obo:CL_0000236 (B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000236 "A lymphocyte of B lineage that is capable of B cell mediated immunity.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000236 "BTO:0000776")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000236 "CALOHA:TS-0068")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000236 "FMA:62869")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000236 "MESH:D001402")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000236 "VHOG:0001480")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000236 "B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000236 "B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000236 "B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000236 "B cell")
EquivalentClasses(obo:CL_0000236 ObjectIntersectionOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019724)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000236 obo:CL_0000945)
SubClassOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826))

# Class: obo:CL_0000237 (keratinizing barrier epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000237 "keratinizing barrier epithelial cell")
SubClassOf(obo:CL_0000237 obo:CL_0000240)
SubClassOf(obo:CL_0000237 obo:CL_0000311)
SubClassOf(obo:CL_0000237 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000114))

# Class: obo:CL_0000238 (non keratinizing barrier epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000238 "non keratinizing barrier epithelial cell")
SubClassOf(obo:CL_0000238 obo:CL_0000240)

# Class: obo:CL_0000239 (brush border epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000239 "An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000239 <https://doi.org/10.1152/ajpgi.00005.2011>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000239 "PMID:25422372")
AnnotationAssertion(rdfs:comment obo:CL_0000239 "All brush border cells are columnar-cuboidal.  The formal logical definition of this term asserts this. Brush border epithelial cells are predominantly found lining the small intestine and the proximal tubules of the kidneys.")
AnnotationAssertion(rdfs:label obo:CL_0000239 "brush border epithelial cell")
EquivalentClasses(obo:CL_0000239 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(obo:CL_0000239 obo:CL_0000075)

# Class: obo:CL_0000240 (stratified squamous epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30422572") Annotation(oboInOwl:hasDbXref "Wikipedia:Epithelium") Annotation(oboInOwl:hasDbXref "Wikipedia:Stratified_squamous_epithelium") obo:IAO_0000115 obo:CL_0000240 "A stratified epithelial cell that is part of squamous epithelium, characterized by multiple layers of cells. The basal layer is directly attached to the basement membrane and the apical layer consists of flattened squamous cells. This provides a protective barrier, commonly found in areas subject to abrasion, such as the skin, oral cavity, and esophagus.")
AnnotationAssertion(rdfs:label obo:CL_0000240 "stratified squamous epithelial cell")
EquivalentClasses(obo:CL_0000240 ObjectIntersectionOf(obo:CL_0000079 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006915)))
SubClassOf(obo:CL_0000240 obo:CL_0000076)

# Class: obo:CL_0000241 (stratified cuboidal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30422572") Annotation(oboInOwl:hasDbXref "Wikipedia:Stratified_cuboidal_epithelium") obo:IAO_0000115 obo:CL_0000241 "A stratified epithelial cell that is part of cuboidal epithelium, characterized by multiple layers of cuboidal cells forming the apical layer. This provides a protective lining for ducts in large glands, such as sweat glands.")
AnnotationAssertion(rdfs:label obo:CL_0000241 "stratified cuboidal epithelial cell")
EquivalentClasses(obo:CL_0000241 ObjectIntersectionOf(obo:CL_0000079 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010077)))
SubClassOf(obo:CL_0000241 obo:CL_0000075)

# Class: obo:CL_0000242 (Merkel cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D018862") Annotation(oboInOwl:hasDbXref "PMID:19834574") Annotation(oboInOwl:hasDbXref "PMID:2274847") Annotation(oboInOwl:hasDbXref "PMID:24862916") Annotation(oboInOwl:hasDbXref "PMID:30415995") Annotation(oboInOwl:hasDbXref "Wikipedia:Merkel_cell") obo:IAO_0000115 obo:CL_0000242 "A specialized epithelial cell located in the skin epidermis and certain mucosal epithelia. It functions as a mechanoreceptor for light touch by forming synapse-like contacts with somatosensory afferent nerve endings, contributing to slowly adapting type I (SAI) tactile responses. Characterized by dense-core neuroendocrine granules, the Merkel cell exhibits both sensory and neuroendocrine properties, including regulated neurotransmitter release via SNARE complex-dependent mechanisms. Its development in mice depends on the transcription factor Atoh1.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000242 "FMA:70548")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000242 "Merkel's cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24862916") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000242 "MC")
AnnotationAssertion(rdfs:label obo:CL_0000242 "Merkel cell")
SubClassOf(obo:CL_0000242 obo:CL_0000066)
SubClassOf(obo:CL_0000242 obo:CL_0000123)
SubClassOf(obo:CL_0000242 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031201))
SubClassOf(obo:CL_0000242 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007269))

# Class: obo:CL_0000243 (obsolete glial cell (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009457") obo:IAO_0000115 obo:CL_0000243 "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000243 <https://github.com/obophenotype/cell-ontology/issues/715>)
AnnotationAssertion(rdfs:comment obo:CL_0000243 "This is a grouping class that is no longer needed or wanted.")
AnnotationAssertion(rdfs:label obo:CL_0000243 "obsolete glial cell (sensu Vertebrata)")
AnnotationAssertion(owl:deprecated obo:CL_0000243 "true"^^xsd:boolean)

# Class: obo:CL_0000244 (transitional epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000244 "A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000244 "FMA:66778")
AnnotationAssertion(rdfs:label obo:CL_0000244 "transitional epithelial cell")
SubClassOf(obo:CL_0000244 obo:CL_0000066)

# Class: obo:CL_0000245 (obsolete passage cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000245 "Obsolete. Use PO:0000353 from Plant Ontology instead. Cell in exodermis or endodermis that remains thin walled when the associated cells develop thick secondary walls. Has casparian strip in endodermis.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000245 obo:PO_0000353)
AnnotationAssertion(rdfs:label obo:CL_0000245 "obsolete passage cell")
AnnotationAssertion(owl:deprecated obo:CL_0000245 "true"^^xsd:boolean)

# Class: obo:CL_0000246 (Mauthner neuron)

AnnotationAssertion(rdfs:label obo:CL_0000246 "Mauthner neuron")
SubClassOf(obo:CL_0000246 obo:CL_0000099)

# Class: obo:CL_0000247 (Rohon-Beard neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VHOG:0001484") obo:IAO_0000115 obo:CL_0000247 "Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000247 "AAO:0010316")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000247 "EFO:0003711")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000247 "VHOG:0001484")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000247 "ZFA:0009150")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VHOG:0001484") oboInOwl:hasExactSynonym obo:CL_0000247 "Rohon Beard cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000247 "Rohon-Beard cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VHOG:0001484") oboInOwl:hasRelatedSynonym obo:CL_0000247 "RB neuron")
AnnotationAssertion(rdfs:label obo:CL_0000247 "Rohon-Beard neuron")
SubClassOf(obo:CL_0000247 obo:CL_0000531)

# Class: obo:CL_0000248 (obsolete microsporocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000248 "Obsolete. Use PO:0020047 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000248 obo:PO_0020047)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000248 "pollen mother cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000248 "primary sporogenous cell")
AnnotationAssertion(rdfs:label obo:CL_0000248 "obsolete microsporocyte")
AnnotationAssertion(owl:deprecated obo:CL_0000248 "true"^^xsd:boolean)

# Class: obo:CL_0000249 (hatching gland cell)

AnnotationAssertion(rdfs:label obo:CL_0000249 "hatching gland cell")
SubClassOf(obo:CL_0000249 obo:CL_0000151)

# Class: obo:CL_0000250 (obsolete megaspore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000250 "Obsolete. Use PO:0020019 from Plant Ontology instead. A haploid (1n) spore developing into a female gametophyte in heterosporous plants.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000250 obo:PO_0020019)
AnnotationAssertion(rdfs:label obo:CL_0000250 "obsolete megaspore")
AnnotationAssertion(owl:deprecated obo:CL_0000250 "true"^^xsd:boolean)

# Class: obo:CL_0000251 (extramedullary cell)

AnnotationAssertion(rdfs:label obo:CL_0000251 "extramedullary cell")
SubClassOf(obo:CL_0000251 obo:CL_0000101)

# Class: obo:CL_0000252 (obsolete microspore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000252 "Obsolete. Use PO:0020048 from Plant Ontology instead. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000252 obo:PO_0020048)
AnnotationAssertion(rdfs:label obo:CL_0000252 "obsolete microspore")
AnnotationAssertion(owl:deprecated obo:CL_0000252 "true"^^xsd:boolean)

# Class: obo:CL_0000253 (eurydendroid cell)

AnnotationAssertion(rdfs:label obo:CL_0000253 "eurydendroid cell")
SubClassOf(obo:CL_0000253 obo:CL_0000527)

# Class: obo:CL_0000254 (obsolete egg cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000254 "Obsolete. Use PO:0020094 from Plant Ontology instead. The female gamete of plants.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000254 obo:PO_0020094)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000254 "female gametophyte egg cell")
AnnotationAssertion(rdfs:label obo:CL_0000254 "obsolete egg cell")
AnnotationAssertion(owl:deprecated obo:CL_0000254 "true"^^xsd:boolean)

# Class: obo:CL_0000255 (eukaryotic cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000255 "MESH:D005057")
AnnotationAssertion(rdfs:label obo:CL_0000255 "eukaryotic cell")
EquivalentClasses(obo:CL_0000255 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_2759)))
DisjointClasses(obo:CL_0000255 obo:CL_0000520)

# Class: obo:CL_0000256 (uric acid accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000256 "uric acid accumulating cell")
SubClassOf(obo:CL_0000256 obo:CL_0000325)

# Class: obo:CL_0000257 (Eumycetozoan cell)

AnnotationAssertion(rdfs:label obo:CL_0000257 "Eumycetozoan cell")
EquivalentClasses(obo:CL_0000257 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_142796)))
SubClassOf(obo:CL_0000257 obo:CL_0000255)

# Class: obo:CL_0000258 (obsolete fiber tracheid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000258 "Obsolete. Use PO:0000355 from Plant Ontology instead. A fiber like tracheid in the secondary xylem; commonly thick walled, with pointed ends and bordered pits that have lenticular to slit like apertures.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000258 obo:PO_0000355)
AnnotationAssertion(rdfs:label obo:CL_0000258 "obsolete fiber tracheid")
AnnotationAssertion(owl:deprecated obo:CL_0000258 "true"^^xsd:boolean)

# Class: obo:CL_0000259 (obsolete aggregate cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000259 obo:DDANAT_0000403)
AnnotationAssertion(rdfs:label obo:CL_0000259 "obsolete aggregate cell")
AnnotationAssertion(owl:deprecated obo:CL_0000259 "true"^^xsd:boolean)

# Class: obo:CL_0000260 (obsolete mucilage cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000260 "Obsolete. Use PO:0000373 from Plant Ontology instead. Cell containing mucilages or gums or similar carbohydrate material characterized by the property of swelling in water.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000260 obo:PO_0000373)
AnnotationAssertion(rdfs:label obo:CL_0000260 "obsolete mucilage cell")
AnnotationAssertion(owl:deprecated obo:CL_0000260 "true"^^xsd:boolean)

# Class: obo:CL_0000261 (obsolete anterior cell)

AnnotationAssertion(oboInOwl:consider obo:CL_0000261 "http://purl.obolibrary.org/obo/DDANAT_0000002"^^xsd:anyURI)
AnnotationAssertion(oboInOwl:consider obo:CL_0000261 "false"^^xsd:boolean)
AnnotationAssertion(rdfs:comment obo:CL_0000261 "Obsoleted becuase this term has an overly general name, no definition, and by it's classification appears to refer to a very specific cell type in dictystelium.  If needed, the term should be in DDANAT - probably as a subclass of http://purl.obolibrary.org/obo/DDANAT_0000002")
AnnotationAssertion(rdfs:label obo:CL_0000261 "obsolete anterior cell")
AnnotationAssertion(owl:deprecated obo:CL_0000261 "true"^^xsd:boolean)

# Class: obo:CL_0000262 (obsolete guard mother cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000262 "Obsolete. Use PO:0000351 from Plant Ontology instead. An epidermal cell that divides to produce the guard cells.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000262 obo:PO_0000351)
AnnotationAssertion(rdfs:label obo:CL_0000262 "obsolete guard mother cell")
AnnotationAssertion(owl:deprecated obo:CL_0000262 "true"^^xsd:boolean)

# Class: obo:CL_0000263 (obsolete vegetative cell (sensu Mycetozoa))

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000263 obo:DDANAT_0000002)
AnnotationAssertion(rdfs:label obo:CL_0000263 "obsolete vegetative cell (sensu Mycetozoa)")
AnnotationAssertion(owl:deprecated obo:CL_0000263 "true"^^xsd:boolean)

# Class: obo:CL_0000264 (obsolete phloem initial)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000264 "Obsolete. Use PO:0000400 from Plant Ontology instead. A cambial cell on the phloem side of the cambial zone that is the source of one or more cells arising by periclinal divisions and differentiating into phloem elements with or without additional divisions in various planes.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000264 obo:PO_0000400)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000264 "phloem mother cell")
AnnotationAssertion(rdfs:label obo:CL_0000264 "obsolete phloem initial")
AnnotationAssertion(owl:deprecated obo:CL_0000264 "true"^^xsd:boolean)

# Class: obo:CL_0000265 (obsolete anterior like cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000265 obo:DDANAT_0000404)
AnnotationAssertion(rdfs:label obo:CL_0000265 "obsolete anterior like cell")
AnnotationAssertion(owl:deprecated obo:CL_0000265 "true"^^xsd:boolean)

# Class: obo:CL_0000266 (obsolete meristemoid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000266 "Obsolete. Use PO:0004011 from Plant Ontology instead. A cell constituting an active locus of meristematic activity in a tissue composed of somewhat older, differentiating cells.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000266 obo:PO_0004011)
AnnotationAssertion(rdfs:label obo:CL_0000266 "obsolete meristemoid")
AnnotationAssertion(owl:deprecated obo:CL_0000266 "true"^^xsd:boolean)

# Class: obo:CL_0000267 (obsolete prespore cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000267 obo:DDANAT_0000405)
AnnotationAssertion(rdfs:label obo:CL_0000267 "obsolete prespore cell")
AnnotationAssertion(owl:deprecated obo:CL_0000267 "true"^^xsd:boolean)

# Class: obo:CL_0000268 (obsolete sieve element)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000268 "Obsolete. Consult Plant Ontology instead. The cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. Classified into sieve cell and sieve tube member.")
AnnotationAssertion(rdfs:label obo:CL_0000268 "obsolete sieve element")
AnnotationAssertion(owl:deprecated obo:CL_0000268 "true"^^xsd:boolean)

# Class: obo:CL_0000269 (obsolete prestalk cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000269 obo:DDANAT_0000406)
AnnotationAssertion(rdfs:label obo:CL_0000269 "obsolete prestalk cell")
AnnotationAssertion(owl:deprecated obo:CL_0000269 "true"^^xsd:boolean)

# Class: obo:CL_0000270 (obsolete subsidiary cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:047124520") obo:IAO_0000115 obo:CL_0000270 "Obsolete. Use PO:0000284 from Plant Ontology instead. An epidermal cell associated with a stoma and at least morphologically distinguishable from the epidermal cells composing the groundmass of the tissue.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000270 obo:PO_0000284)
AnnotationAssertion(rdfs:label obo:CL_0000270 "obsolete subsidiary cell")
AnnotationAssertion(owl:deprecated obo:CL_0000270 "true"^^xsd:boolean)

# Class: obo:CL_0000271 (obsolete prestalk A cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000271 obo:DDANAT_0000408)
AnnotationAssertion(rdfs:label obo:CL_0000271 "obsolete prestalk A cell")
AnnotationAssertion(owl:deprecated obo:CL_0000271 "true"^^xsd:boolean)

# Class: obo:CL_0000272 (obsolete cambial initial)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000272 "OBSOLETE, use term from Plant Ontology. A cell localized in the vascular cambium or phellogen. Its periclinal division can contribute cells either to the outside or to the inside of the axis; in vascular cambium, classified into fusiform initials (source of axial cells of xylem and phloem) and ray initials (source of the ray cells).")
AnnotationAssertion(rdfs:comment obo:CL_0000272 "replaced_by PO:0000295")
AnnotationAssertion(rdfs:label obo:CL_0000272 "obsolete cambial initial")
AnnotationAssertion(owl:deprecated obo:CL_0000272 "true"^^xsd:boolean)

# Class: obo:CL_0000273 (obsolete prestalk AB cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000273 obo:DDANAT_0000410)
AnnotationAssertion(rdfs:label obo:CL_0000273 "obsolete prestalk AB cell")
AnnotationAssertion(owl:deprecated obo:CL_0000273 "true"^^xsd:boolean)

# Class: obo:CL_0000274 (obo:CL_0000274)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000274 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000274 obo:CL_0000009)
AnnotationAssertion(owl:deprecated obo:CL_0000274 "true"^^xsd:boolean)

# Class: obo:CL_0000275 (obsolete prestalk B cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000275 obo:DDANAT_0000409)
AnnotationAssertion(rdfs:label obo:CL_0000275 "obsolete prestalk B cell")
AnnotationAssertion(owl:deprecated obo:CL_0000275 "true"^^xsd:boolean)

# Class: obo:CL_0000276 (obsolete sclerenchyma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000276 "Obsolete. Use PO:0000077 from Plant Ontology instead. Cell variable in form and size, being more or less thick, often lignified, secondary walls. Belongs to the category of subcells and may or may not be devoid of protoplast at maturity.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000276 obo:PO_0000077)
AnnotationAssertion(rdfs:label obo:CL_0000276 "obsolete sclerenchyma cell")
AnnotationAssertion(owl:deprecated obo:CL_0000276 "true"^^xsd:boolean)

# Class: obo:CL_0000277 (obsolete prestalk I cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DictyBase:DDB") obo:IAO_0000115 obo:CL_0000277 "OBSOLETE: Initial population of prestalk cells that activate the ecmA promoter at the mound stage and that presumably further differentiate into pstA and pstO cells.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000277 obo:DDANAT_0000406)
AnnotationAssertion(rdfs:comment obo:CL_0000277 "This cell type does not exist in Dictyostelium. it has been long deleted in their anatomy ontology.")
AnnotationAssertion(rdfs:label obo:CL_0000277 "obsolete prestalk I cell")
AnnotationAssertion(owl:deprecated obo:CL_0000277 "true"^^xsd:boolean)

# Class: obo:CL_0000278 (obsolete central cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000278 "Obsolete. Use PO:0020090 from Plant Ontology instead. OBSOLETED, use term from Plant Ontology. A cell containing the two polar nuclei which, after double fertilization, will develop into the endosperm.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000278 obo:PO_0020090)
AnnotationAssertion(rdfs:label obo:CL_0000278 "obsolete central cell")
AnnotationAssertion(owl:deprecated obo:CL_0000278 "true"^^xsd:boolean)

# Class: obo:CL_0000279 (obsolete prestalk 0 cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000279 obo:DDANAT_0000407)
AnnotationAssertion(rdfs:label obo:CL_0000279 "obsolete prestalk 0 cell")
AnnotationAssertion(owl:deprecated obo:CL_0000279 "true"^^xsd:boolean)

# Class: obo:CL_0000280 (obsolete generative cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000280 "Obsolete. Use PO:0020097 from Plant Ontology instead. The cell that will give rise to the generative nuclei which will participate in fertilization.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000280 obo:PO_0020097)
AnnotationAssertion(rdfs:label obo:CL_0000280 "obsolete generative cell")
AnnotationAssertion(owl:deprecated obo:CL_0000280 "true"^^xsd:boolean)

# Class: obo:CL_0000281 (obsolete pstAB/ALC)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000281 obo:DDANAT_0000411)
AnnotationAssertion(rdfs:label obo:CL_0000281 "obsolete pstAB/ALC")
AnnotationAssertion(owl:deprecated obo:CL_0000281 "true"^^xsd:boolean)

# Class: obo:CL_0000282 (obsolete trichome)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") Annotation(oboInOwl:hasDbXref "PMID:10938806") obo:IAO_0000115 obo:CL_0000282 "Obsolete. Use PO:0000282 from Plant Ontology instead. An outgrowth from the epidermis. Trichomes vary in size and complexity and include hairs, scales, and other structures and may be glandular. In Arabidopsis, patterning of trichome development is not random but does not appear to be lineage-based like stomata.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000282 obo:PO_0000282)
AnnotationAssertion(rdfs:label obo:CL_0000282 "obsolete trichome")
AnnotationAssertion(owl:deprecated obo:CL_0000282 "true"^^xsd:boolean)

# Class: obo:CL_0000283 (obsolete pstO/ALC)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000283 obo:DDANAT_0000412)
AnnotationAssertion(rdfs:label obo:CL_0000283 "obsolete pstO/ALC")
AnnotationAssertion(owl:deprecated obo:CL_0000283 "true"^^xsd:boolean)

# Class: obo:CL_0000284 (obsolete companion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0879015322") obo:IAO_0000115 obo:CL_0000284 "Obsolete. Use PO:0000071 from Plant Ontology instead. A specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000284 obo:PO_0000071)
AnnotationAssertion(rdfs:label obo:CL_0000284 "obsolete companion cell")
AnnotationAssertion(owl:deprecated obo:CL_0000284 "true"^^xsd:boolean)

# Class: obo:CL_0000285 (obsolete stalk cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000285 obo:DDANAT_0000413)
AnnotationAssertion(rdfs:label obo:CL_0000285 "obsolete stalk cell")
AnnotationAssertion(owl:deprecated obo:CL_0000285 "true"^^xsd:boolean)

# Class: obo:CL_0000286 (hyphal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000286 "A cell of a filament of a fungal mycelium.")
AnnotationAssertion(rdfs:label obo:CL_0000286 "hyphal cell")
SubClassOf(obo:CL_0000286 obo:CL_0000521)

# Class: obo:CL_0000287 (eye photoreceptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000287 "eye photoreceptor cell")
EquivalentClasses(obo:CL_0000287 ObjectIntersectionOf(obo:CL_0000210 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000970)))
SubClassOf(obo:CL_0000287 obo:CL_0000210)

# Class: obo:CL_0000288 (obsolete synergid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:047125208") obo:IAO_0000115 obo:CL_0000288 "Obsolete. Use PO:0000191 from Plant Ontology instead. A cell in the micropylar end of the embryo sac associated with the egg in the egg apparatus of angiosperms. Plays a vital role in fertilization.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000288 obo:PO_0000191)
AnnotationAssertion(rdfs:label obo:CL_0000288 "obsolete synergid")
AnnotationAssertion(owl:deprecated obo:CL_0000288 "true"^^xsd:boolean)

# Class: obo:CL_0000289 (obsolete chemotactic amoeboid cell (sensu Mycetozoa))

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000289 obo:DDANAT_0000402)
AnnotationAssertion(rdfs:label obo:CL_0000289 "obsolete chemotactic amoeboid cell (sensu Mycetozoa)")
AnnotationAssertion(owl:deprecated obo:CL_0000289 "true"^^xsd:boolean)

# Class: obo:CL_0000290 (obsolete xylem fiber cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000290 "Obsolete. Use PO:0000274 from Plant Ontology instead. A fiber of the xylem tissue, Two types are recognized in the secondary xylem: fiber tracheids and libriform fibers.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000290 obo:PO_0000274)
AnnotationAssertion(rdfs:label obo:CL_0000290 "obsolete xylem fiber cell")
AnnotationAssertion(owl:deprecated obo:CL_0000290 "true"^^xsd:boolean)

# Class: obo:CL_0000291 (obsolete spore (sensu Mycetozoa))

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000291 obo:DDANAT_0000414)
AnnotationAssertion(rdfs:label obo:CL_0000291 "obsolete spore (sensu Mycetozoa)")
AnnotationAssertion(owl:deprecated obo:CL_0000291 "true"^^xsd:boolean)

# Class: obo:CL_0000292 (obsolete guard cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000292 "Obsolete. Use PO:0000293 from Plant Ontology instead. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000292 obo:PO_0000293)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000292 "stomatal guard cell")
AnnotationAssertion(rdfs:label obo:CL_0000292 "obsolete guard cell")
AnnotationAssertion(owl:deprecated obo:CL_0000292 "true"^^xsd:boolean)

# Class: obo:CL_0000293 (obsolete structural cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:sr") obo:IAO_0000115 obo:CL_0000293 "OBSOLETE. A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000293 <https://github.com/obophenotype/cell-ontology/issues/3010>)
AnnotationAssertion(rdfs:comment obo:CL_0000293 "Unsustainable grouping term.")
AnnotationAssertion(rdfs:label obo:CL_0000293 "obsolete structural cell")
AnnotationAssertion(owl:deprecated obo:CL_0000293 "true"^^xsd:boolean)

# Class: obo:CL_0000294 (obsolete sieve cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000294 "Obsolete. Consult Plant Ontology instead. A type of sieve element that has relatively undifferentiated sieve areas (with narrow pores), rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants.")
AnnotationAssertion(rdfs:label obo:CL_0000294 "obsolete sieve cell")
AnnotationAssertion(owl:deprecated obo:CL_0000294 "true"^^xsd:boolean)

# Class: obo:CL_0000295 (somatotropin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000295 "A peptide hormone secreting cell that produces growth hormone, somatotropin.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000295 "growth hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000295 "somatotrophin secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000295 "somatotropin secreting cell")
EquivalentClasses(obo:CL_0000295 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030252)))

# Class: obo:CL_0000296 (obsolete vegetative cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0140514031") Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000296 "Obsolete. Use PO:0020099 from Plant Ontology instead. Cell type formed after the first mitotic division of the microgametophye, The nucleus of this cell migrates to the tip of the pollen tube after germination and disintegrates when the pollen tube penetrates the nucellus.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000296 obo:PO_0020099)
AnnotationAssertion(rdfs:label obo:CL_0000296 "obsolete vegetative cell")
AnnotationAssertion(owl:deprecated obo:CL_0000296 "true"^^xsd:boolean)

# Class: obo:CL_0000297 (obsolete socket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10938806") obo:IAO_0000115 obo:CL_0000297 "Obsolete. Use PO:0000115 from Plant Ontology instead. A cell that surrounds a trichome and provides support for the trichome.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000297 obo:PO_0000115)
AnnotationAssertion(rdfs:label obo:CL_0000297 "obsolete socket cell")
AnnotationAssertion(owl:deprecated obo:CL_0000297 "true"^^xsd:boolean)

# Class: obo:CL_0000298 (obsolete xylem element)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000298 "Obsolete. Use PO:0000273 from Plant Ontology instead. A cell composing the xylem.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000298 obo:PO_0000273)
AnnotationAssertion(rdfs:label obo:CL_0000298 "obsolete xylem element")
AnnotationAssertion(owl:deprecated obo:CL_0000298 "true"^^xsd:boolean)

# Class: obo:CL_0000299 (obsolete trichoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000299 "OBSOLETED. Commonly used for a cell in root epidermis that gives rise to a root hair. The daughter cell produced by the asymmetric division of a root epidermal cell that gives rise to a root hair.")
AnnotationAssertion(rdfs:comment obo:CL_0000299 "Obsoleted. Use trichoblast from the plant ontology (PO:0000262).")
AnnotationAssertion(rdfs:label obo:CL_0000299 "obsolete trichoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000299 "true"^^xsd:boolean)

# Class: obo:CL_0000300 (gamete)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000300 "A mature sexual reproductive cell having a single set of unpaired chromosomes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000300 "CALOHA:TS-0395")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000300 "FMA:18649")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000300 "haploid nucleated cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000300 "haploid germ cell")
AnnotationAssertion(rdfs:label obo:CL_0000300 "gamete")
EquivalentClasses(obo:CL_0000300 ObjectIntersectionOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009566)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000300 obo:CL_0000586)

# Class: obo:CL_0000301 (pole cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1017/CBO9780511818202.015") obo:IAO_0000115 obo:CL_0000301 "A primordial germ cell of insects. Such cells form at the posterior pole of the early embryo.")
AnnotationAssertion(rdfs:label obo:CL_0000301 "pole cell")
SubClassOf(obo:CL_0000301 obo:CL_0000670)

# Class: obo:CL_0000302 (obsolete IgM B cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000302 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000302 "Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000302 "obsolete IgM B cell")
AnnotationAssertion(owl:deprecated obo:CL_0000302 "true"^^xsd:boolean)

# Class: obo:CL_0000303 (obsolete IgG B cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000303 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000303 "Not a differentiation state per se, and IgG isotypes vary by species; consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000303 "obsolete IgG B cell")
AnnotationAssertion(owl:deprecated obo:CL_0000303 "true"^^xsd:boolean)

# Class: obo:CL_0000304 (obsolete IgA B cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000304 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000304 "Not a differentiation state per se, and IgA isotypes vary by species. Consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000304 "obsolete IgA B cell")
AnnotationAssertion(owl:deprecated obo:CL_0000304 "true"^^xsd:boolean)

# Class: obo:CL_0000305 (obsolete IgE B cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000305 "OBSOLETE (was not defined before being made obsolete).")
AnnotationAssertion(rdfs:comment obo:CL_0000305 "Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead.")
AnnotationAssertion(rdfs:label obo:CL_0000305 "obsolete IgE B cell")
AnnotationAssertion(owl:deprecated obo:CL_0000305 "true"^^xsd:boolean)

# Class: obo:CL_0000306 (crystallin accumulating cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000306 "lens cell")
AnnotationAssertion(rdfs:label obo:CL_0000306 "crystallin accumulating cell")
SubClassOf(obo:CL_0000306 obo:CL_0000325)

# Class: obo:CL_0000307 (tracheal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000307 "An epithelial cell found in the trachea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000307 "FMA:74793")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000307 "tracheocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000307 "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'")
AnnotationAssertion(rdfs:label obo:CL_0000307 "tracheal epithelial cell")
EquivalentClasses(obo:CL_0000307 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003126)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000307 obo:CL_0002202)
SubClassOf(obo:CL_0000307 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000377))

# Class: obo:CL_0000308 (metal ion accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000308 "metal ion accumulating cell")
SubClassOf(obo:CL_0000308 obo:CL_0000325)

# Class: obo:CL_0000309 (copper accumulating cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000309 "cuprophilic cell")
AnnotationAssertion(rdfs:label obo:CL_0000309 "copper accumulating cell")
SubClassOf(obo:CL_0000309 obo:CL_0000308)

# Class: obo:CL_0000310 (iron accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000310 "iron accumulating cell")
SubClassOf(obo:CL_0000310 obo:CL_0000308)

# Class: obo:CL_0000311 (keratin accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000311 "keratin accumulating cell")
SubClassOf(obo:CL_0000311 obo:CL_0000325)

# Class: obo:CL_0000312 (keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15749908") Annotation(oboInOwl:hasDbXref "PMID:19256306") Annotation(oboInOwl:hasDbXref "PMID:19727116") Annotation(oboInOwl:hasDbXref "PMID:29713660") Annotation(oboInOwl:hasDbXref "PMID:37873034") obo:IAO_0000115 obo:CL_0000312 "An epithelial cell of stratified squamous tissues, including skin, oral mucosa (Hiroshima et al., 2011), and esophagus (Whelan et al., 2018), that produces keratin proteins and secretes antimicrobial peptides to form a resilient barrier against environmental damage, dehydration, pathogens, and microbial invasion. It undergoes successive stages of differentiation marked by changes in keratin expression, supporting tissue integrity, wound repair, and contributing to immune defense.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000312 "BTO:0000667")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000312 "CALOHA:TS-0500")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000312 "FMA:62879")
AnnotationAssertion(rdfs:label obo:CL_0000312 "keratinocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000312 obo:CL_0000237)
SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002775))
SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002776))
SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042060))

# Class: obo:CL_0000313 (serous secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000313 "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000313 "BTO:0003687")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000313 "FMA:62511")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000313 "serous cell")
AnnotationAssertion(rdfs:label obo:CL_0000313 "serous secreting cell")
SubClassOf(obo:CL_0000313 obo:CL_0000159)

# Class: obo:CL_0000314 (milk secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000314 "milk secreting cell")
SubClassOf(obo:CL_0000314 obo:CL_0000151)

# Class: obo:CL_0000315 (tear secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013666") obo:IAO_0000115 obo:CL_0000315 "A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000315 "tears secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000315 "tear secreting cell")
SubClassOf(obo:CL_0000315 obo:CL_0000151)
SubClassOf(obo:CL_0000315 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001817))

# Class: obo:CL_0000316 (obsolete ray initial)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000316 "Obsolete. Use PO:0000082 from Plant Ontology instead. A meristemic ray cell in the vascular cambium that gives rise to ray cells of the secondary xylem and secondary phloem.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000316 obo:PO_0000082)
AnnotationAssertion(rdfs:label obo:CL_0000316 "obsolete ray initial")
AnnotationAssertion(owl:deprecated obo:CL_0000316 "true"^^xsd:boolean)

# Class: obo:CL_0000317 (sebocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D012629") Annotation(oboInOwl:hasDbXref "PMID:19944183") obo:IAO_0000115 obo:CL_0000317 "An epithelial cell that is part of a sebaceous gland. This cell produces and secretes sebum, an oily, lipid-rich substance, through holocrine secretion where the entire cell ruptures to release its contents.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000317 "sebum secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000317 "sebocyte")
EquivalentClasses(obo:CL_0000317 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001821)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000317 obo:CL_0000151)

# Class: obo:CL_0000318 (sweat secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013542") obo:IAO_0000115 obo:CL_0000318 "A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products.")
AnnotationAssertion(rdfs:label obo:CL_0000318 "sweat secreting cell")
SubClassOf(obo:CL_0000318 obo:CL_0000150)
SubClassOf(obo:CL_0000318 obo:CL_0000151)

# Class: obo:CL_0000319 (mucus secreting cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000319 "BTO:0003689")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000319 "mucous cell")
AnnotationAssertion(rdfs:label obo:CL_0000319 "mucus secreting cell")
EquivalentClasses(obo:CL_0000319 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254)))
SubClassOf(obo:CL_0000319 obo:CL_0000159)

# Class: obo:CL_0000320 (obsolete megasporocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000320 "Obsolete. Use PO:0000431 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and produces four haploid (1n) megaspores; also called megaspore mother cell.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000320 obo:PO_0000431)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000320 "archesporial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000320 "megaspore mother cell")
AnnotationAssertion(rdfs:label obo:CL_0000320 "obsolete megasporocyte")
AnnotationAssertion(owl:deprecated obo:CL_0000320 "true"^^xsd:boolean)

# Class: obo:CL_0000321 (obsolete seminal fluid secreting cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000321 <https://github.com/obophenotype/cell-ontology/issues/1149>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000321 obo:CL_0000151)
AnnotationAssertion(oboInOwl:consider obo:CL_0000321 obo:CL_1001597)
AnnotationAssertion(rdfs:label obo:CL_0000321 "obsolete seminal fluid secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000321 "true"^^xsd:boolean)

# Class: obo:CL_0000322 (pulmonary alveolar epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20054144") Annotation(oboInOwl:hasDbXref "PMID:29463737") obo:IAO_0000115 obo:CL_0000322 "An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates.")
AnnotationAssertion(terms:contributor obo:CL_0000322 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_0000322 "2024-09-02T08:27:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000322 "BTO:0000395")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000322 "CALOHA:TS-2168")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000322 "FMA:62499")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000322 "MESH:D056809")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000322 "alveolar epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000322 "alveolus of lung epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000322 "epithelial cell of alveolus of lung")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32491474") oboInOwl:hasExactSynonym obo:CL_0000322 "pneumocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000322 "pneumonocyte")
AnnotationAssertion(rdfs:label obo:CL_0000322 "pulmonary alveolar epithelial cell")
EquivalentClasses(obo:CL_0000322 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004821)))

# Class: obo:CL_0000323 (lysozyme secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000323 "lysozyme secreting cell")
SubClassOf(obo:CL_0000323 obo:CL_0000154)

# Class: obo:CL_0000324 (metanephric mesenchyme stem cell)

AnnotationAssertion(rdfs:label obo:CL_0000324 "metanephric mesenchyme stem cell")
SubClassOf(obo:CL_0000324 obo:CL_0000134)
SubClassOf(obo:CL_0000324 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0000325 (stuff accumulating cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000325 "A cell that is specialised to accumulate a particular substance(s).")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000325 ubprop:_upper_level)
AnnotationAssertion(rdfs:label obo:CL_0000325 "stuff accumulating cell")
SubClassOf(obo:CL_0000325 obo:CL_0000000)

# Class: obo:CL_0000326 (glycogen accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000326 "glycogen accumulating cell")
SubClassOf(obo:CL_0000326 obo:CL_0000325)

# Class: obo:CL_0000327 (extracellular matrix secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000327 "extracellular matrix secreting cell")
SubClassOf(obo:CL_0000327 obo:CL_0000499)

# Class: obo:CL_0000328 (obsolete myelin accumulating cell)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000328 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000328 obo:CL_4023154)
AnnotationAssertion(rdfs:comment obo:CL_0000328 "see: https://github.com/obophenotype/cell-ontology/issues/161")
AnnotationAssertion(rdfs:label obo:CL_0000328 "obsolete myelin accumulating cell")
AnnotationAssertion(owl:deprecated obo:CL_0000328 "true"^^xsd:boolean)

# Class: obo:CL_0000329 (oxygen accumulating cell)

AnnotationAssertion(rdfs:label obo:CL_0000329 "oxygen accumulating cell")
EquivalentClasses(obo:CL_0000329 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015671)))

# Class: obo:CL_0000330 (obsolete collenchymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000330 "Obsolete. Use PO:0000075 from Plant Ontology instead. An elongated living cell with unevenly thickened nonlignified primary walls.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000330 obo:PO_0000075)
AnnotationAssertion(rdfs:label obo:CL_0000330 "obsolete collenchymal cell")
AnnotationAssertion(owl:deprecated obo:CL_0000330 "true"^^xsd:boolean)

# Class: obo:CL_0000331 (obsolete tracheid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000331 "Obsolete. Use PO:0000301 from Plant Ontology instead. A tracheary element of the xylem that has no perforations, as contrasted with a vessel member. May occur in primary and in secondary xylem. May have any kind of secondary wall thickening found in tracheary elements.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000331 obo:PO_0000301)
AnnotationAssertion(rdfs:label obo:CL_0000331 "obsolete tracheid")
AnnotationAssertion(owl:deprecated obo:CL_0000331 "true"^^xsd:boolean)

# Class: obo:CL_0000332 (obsolete atrichoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0387987819") obo:IAO_0000115 obo:CL_0000332 "OBSOLETE, use term from Plant Ontology. A cell formed after asymmetric division of root epidermal cell that does not give rise to a root hair.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000332 obo:PO_0020090)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000332 "non-hair cell")
AnnotationAssertion(rdfs:label obo:CL_0000332 "obsolete atrichoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000332 "true"^^xsd:boolean)

# Class: obo:CL_0000333 (migratory neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2015.02.017") obo:IAO_0000115 obo:CL_0000333 "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000333 "FMA:86667")
AnnotationAssertion(rdfs:label obo:CL_0000333 "migratory neural crest cell")
SubClassOf(obo:CL_0000333 obo:CL_0000000)
SubClassOf(obo:CL_0000333 obo:CL_0000219)
SubClassOf(obo:CL_0000333 obo:CL_0011012)
SubClassOf(obo:CL_0000333 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007004))

# Class: obo:CL_0000334 (vegetative cell (sensu Fungi))

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000334 "BTO:0002307")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000334 "FAO:0000032")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000334 "yeast-form")
AnnotationAssertion(rdfs:label obo:CL_0000334 "vegetative cell (sensu Fungi)")
SubClassOf(obo:CL_0000334 obo:CL_0000521)

# Class: obo:CL_0000335 (mesenchyme condensation cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:5025404") obo:IAO_0000115 obo:CL_0000335 "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.")
AnnotationAssertion(rdfs:label obo:CL_0000335 "mesenchyme condensation cell")
SubClassOf(obo:CL_0000335 obo:CL_0008019)

# Class: obo:CL_0000336 (adrenal medulla chromaffin cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.britannica.com/EBchecked/topic/6405/adrenal-gland") obo:IAO_0000115 obo:CL_0000336 "A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000336 "FMA:69262")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69262") oboInOwl:hasExactSynonym obo:CL_0000336 "medullary chromaffin cell of adrenal gland")
AnnotationAssertion(rdfs:label obo:CL_0000336 "adrenal medulla chromaffin cell")
EquivalentClasses(obo:CL_0000336 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000336 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000336 obo:CL_0000166)
SubClassOf(obo:CL_0000336 obo:CL_0000457)
SubClassOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000011))

# Class: obo:CL_0000337 (obo:CL_0000337)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000337 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000337 obo:CL_0000031)
AnnotationAssertion(owl:deprecated obo:CL_0000337 "true"^^xsd:boolean)

# Class: obo:CL_0000338 (neuroblast (sensu Nematoda and Protostomia))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1295739") obo:IAO_0000115 obo:CL_0000338 "A neural precursor of the central nervous system.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000338 "neuroblast")
AnnotationAssertion(rdfs:label obo:CL_0000338 "neuroblast (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000338 obo:CL_0000047)
SubClassOf(obo:CL_0000338 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33317))

# Class: obo:CL_0000339 (glioblast (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000339 "An early neural cell developing from the early ependymal cell of the neural tube.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000339 "FMA:70564")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000339 "spongioblast")
AnnotationAssertion(rdfs:label obo:CL_0000339 "glioblast (sensu Vertebrata)")
SubClassOf(obo:CL_0000339 obo:CL_0000030)
SubClassOf(obo:CL_0000339 obo:CL_0000123)
SubClassOf(obo:CL_0000339 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000340 (glioblast (sensu Nematoda and Protostomia))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1002/glia.21162") obo:IAO_0000115 obo:CL_0000340 "A precursor of the central nervous system that gives rise to glial cells only.")
AnnotationAssertion(rdfs:label obo:CL_0000340 "glioblast (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000340 obo:CL_0000030)
SubClassOf(obo:CL_0000340 obo:CL_0000130)

# Class: obo:CL_0000341 (pigment cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:RO_0002161 obo:CL_0000341 obo:NCBITaxon_33511)
AnnotationAssertion(rdfs:label obo:CL_0000341 "pigment cell (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000341 obo:CL_0000147)

# Class: obo:CL_0000342 (pigment cell (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000342 "Any animal cell containing pigment granules.")
AnnotationAssertion(rdfs:label obo:CL_0000342 "pigment cell (sensu Vertebrata)")
SubClassOf(obo:CL_0000342 obo:CL_0000147)
SubClassOf(obo:CL_0000342 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000343 (visual pigment cell (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000343 "A pigment cell that is capable of detecting light stimulus that is involved in visual perception.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000343 "FMA:63846")
AnnotationAssertion(rdfs:label obo:CL_0000343 "visual pigment cell (sensu Vertebrata)")
EquivalentClasses(obo:CL_0000343 ObjectIntersectionOf(obo:CL_0000342 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050908)))
SubClassOf(obo:CL_0000343 obo:CL_0000149)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000343 obo:CL_0000342)

# Class: obo:CL_0000344 (obsolete non-visual cell (sensu Vertebrata))

AnnotationAssertion(rdfs:label obo:CL_0000344 "obsolete non-visual cell (sensu Vertebrata)")
AnnotationAssertion(owl:deprecated obo:CL_0000344 "true"^^xsd:boolean)

# Class: obo:CL_0000345 (dental papilla cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000345 "A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp.")
AnnotationAssertion(rdfs:comment obo:CL_0000345 "Merge with odontoblast?")
AnnotationAssertion(rdfs:label obo:CL_0000345 "dental papilla cell")
SubClassOf(obo:CL_0000345 obo:CL_0008019)
SubClassOf(obo:CL_0000345 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001763))
SubClassOf(obo:CL_0000345 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000346 (hair follicle dermal papilla cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28418596") Annotation(oboInOwl:hasDbXref "PMID:39798934") Annotation(oboInOwl:hasDbXref "PMID:40867641") obo:IAO_0000115 obo:CL_0000346 "A specialized fibroblast that resides in the dermal papilla located at the bottom of hair follicles. This cell orchestrates reciprocal epithelial-mesenchymal signaling essential for hair follicle morphogenesis and cycling, regulating matrix cell proliferation and differentiation to control hair shaft size, shape, and growth. The dermal papilla cell is replenished each hair cycle from bipotent hair follicle dermal stem cells in the dermal sheath that simultaneously self-renew and contribute progeny to the papilla, particularly during anagen.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39798934") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000346 "hair follicle DPC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21444748") rdfs:comment obo:CL_0000346 "The dermal papilla contains functionally heterogeneous Sox2-positive subpopulations that serve as a niche for multipotent stem cells. These cells exhibit progenitor properties, generate skin-derived precursors (SKPs), and can differentiate into adipogenic and osteogenic lineages.")
AnnotationAssertion(rdfs:label obo:CL_0000346 "hair follicle dermal papilla cell")
EquivalentClasses(obo:CL_0000346 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000412)))
SubClassOf(obo:CL_0000346 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042634))
SubClassOf(obo:CL_0000346 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060638))
SubClassOf(obo:CL_0000346 ObjectSomeValuesFrom(obo:RO_0002596 obo:GO_0031069))

# Class: obo:CL_0000347 (scleral cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000347 "A cell of the sclera of the eye.")
AnnotationAssertion(rdfs:label obo:CL_0000347 "scleral cell")
EquivalentClasses(obo:CL_0000347 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001773)))
SubClassOf(obo:CL_0000347 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000348 (choroidal cell of the eye)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000348 "A cell that is part of optic choroid.")
AnnotationAssertion(rdfs:label obo:CL_0000348 "choroidal cell of the eye")
EquivalentClasses(obo:CL_0000348 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001776)))
SubClassOf(obo:CL_0000348 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0000349 (extraembryonic cell)

AnnotationAssertion(rdfs:label obo:CL_0000349 "extraembryonic cell")
EquivalentClasses(obo:CL_0000349 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000478)))

# Class: obo:CL_0000350 (amnioserosal cell)

AnnotationAssertion(rdfs:label obo:CL_0000350 "amnioserosal cell")
EquivalentClasses(obo:CL_0000350 ObjectIntersectionOf(obo:CL_0000349 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010302)))

# Class: obo:CL_0000351 (trophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D014327") Annotation(oboInOwl:hasDbXref "PMID:37630754") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-84725-8") obo:IAO_0000115 obo:CL_0000351 "An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000351 "FMA:83028")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-84725-8") oboInOwl:hasExactSynonym obo:CL_0000351 "trophoblastic cell")
AnnotationAssertion(rdfs:label obo:CL_0000351 "trophoblast cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000351 obo:CL_0000349)
SubClassOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_1000274))

# Class: obo:CL_0000352 (epiblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000352 "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.")
AnnotationAssertion(rdfs:label obo:CL_0000352 "epiblast cell")
SubClassOf(obo:CL_0000352 obo:CL_0000052)

# Class: obo:CL_0000353 (blastoderm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D001756") obo:IAO_0000115 obo:CL_0000353 "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000353 "BTO:0001473")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000353 "FMA:72551")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000353 "blastomere")
AnnotationAssertion(rdfs:label obo:CL_0000353 "blastoderm cell")
SubClassOf(obo:CL_0000353 obo:CL_0000007)

# Class: obo:CL_0000354 (blastemal cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000354 "ncithesaurus:Blastemal_Cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000354 "blastema cell")
AnnotationAssertion(rdfs:label obo:CL_0000354 "blastemal cell")
SubClassOf(obo:CL_0000354 obo:CL_0000048)

# Class: obo:CL_0000355 (multi-potent skeletal muscle stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18282570") obo:IAO_0000115 obo:CL_0000355 "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000355 "FMA:86767")
AnnotationAssertion(rdfs:comment obo:CL_0000355 "Multi-potency demonstrated ex vivo.  At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.")
AnnotationAssertion(rdfs:label obo:CL_0000355 "multi-potent skeletal muscle stem cell")
EquivalentClasses(obo:CL_0000355 ObjectIntersectionOf(obo:CL_0000048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000355 obo:CL_0000048)

# Class: obo:CL_0000356 (hair matrix stem cell)

AnnotationAssertion(rdfs:label obo:CL_0000356 "hair matrix stem cell")
SubClassOf(obo:CL_0000356 obo:CL_0000035)

# Class: obo:CL_0000357 (stratified epithelial stem cell)

AnnotationAssertion(rdfs:label obo:CL_0000357 "stratified epithelial stem cell")
SubClassOf(obo:CL_0000357 obo:CL_0000036)

# Class: obo:CL_0000358 (sphincter associated smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") obo:IAO_0000115 obo:CL_0000358 "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.")
AnnotationAssertion(rdfs:label obo:CL_0000358 "sphincter associated smooth muscle cell")
EquivalentClasses(obo:CL_0000358 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004590)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000358 obo:CL_0000192)

# Class: obo:CL_0000359 (vascular associated smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000359 "A smooth muscle cell associated with the vasculature.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000359 "VSMC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000359 "vascular smooth muscle cell")
AnnotationAssertion(rdfs:label obo:CL_0000359 "vascular associated smooth muscle cell")
EquivalentClasses(obo:CL_0000359 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002049)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000359 obo:CL_0000192)
SubClassOf(obo:CL_0000359 obo:CL_4033054)

# Class: obo:CL_0000360 (morula cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009028") obo:IAO_0000115 obo:CL_0000360 "A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass.")
AnnotationAssertion(rdfs:label obo:CL_0000360 "morula cell")
SubClassOf(obo:CL_0000360 obo:CL_0000007)
SubClassOf(obo:CL_0000360 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000085))

# Class: obo:CL_0000361 (gastrula cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D005775") obo:IAO_0000115 obo:CL_0000361 "A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers.")
AnnotationAssertion(rdfs:label obo:CL_0000361 "gastrula cell")
SubClassOf(obo:CL_0000361 obo:CL_0000007)
SubClassOf(obo:CL_0000361 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004734))

# Class: obo:CL_0000362 (epidermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Flybase:dsj") Annotation(oboInOwl:hasDbXref "MA:ma") obo:IAO_0000115 obo:CL_0000362 "An epithelial cell of the integument (the outer layer of an organism).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000362 "BTO:0001470")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000362 "CALOHA:TS-0283")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000362 "FMA:62411")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000362 "MESH:D000078404")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:62411") oboInOwl:hasExactSynonym obo:CL_0000362 "cell of epidermis")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:62411") oboInOwl:hasNarrowSynonym obo:CL_0000362 "epithelial cell of skin")
AnnotationAssertion(rdfs:label obo:CL_0000362 "epidermal cell")
EquivalentClasses(obo:CL_0000362 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007376)))
SubClassOf(obo:CL_0000362 obo:CL_0002159)

# Class: obo:CL_0000363 (obsolete axial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000363 "Obsolete. Use PO:0000081 from Plant Ontology instead. OBSOLETE, use term from the Plant Ontology. A secondary vascular cell that develops from the fusiform cambial initials and oriented with their longest diameter parallel with the main axis of stem or root. These cells make up the axial system, also known as vertical or longitudinal system.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000363 obo:PO_0000081)
AnnotationAssertion(rdfs:label obo:CL_0000363 "obsolete axial cell")
AnnotationAssertion(owl:deprecated obo:CL_0000363 "true"^^xsd:boolean)

# Class: obo:CL_0000364 (obsolete ray cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000364 "Obsolete. Consult Plant Ontology. A cell that develops from the ray initial and composes all rays (panels of tissue variable in height and width, formed by the ray initials in the vascular cambium and extending radially in the secondary xylem and secondary phloem) in the secondary vascular tissues.")
AnnotationAssertion(rdfs:label obo:CL_0000364 "obsolete ray cell")
AnnotationAssertion(owl:deprecated obo:CL_0000364 "true"^^xsd:boolean)

# Class: obo:CL_0000365 (animal zygote)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000365 "Diploid cell produced by the fusion of sperm cell nucleus and egg cell.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000365 "zygote")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000365 "BTO:0000854")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000365 "EHDAA2:0004546")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000365 "FMA:72395")
AnnotationAssertion(rdfs:label obo:CL_0000365 "animal zygote")
EquivalentClasses(obo:CL_0000365 ObjectIntersectionOf(obo:CL_0010017 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33208)))
SubClassOf(obo:CL_0000365 obo:CL_0000007)
SubClassOf(obo:CL_0000365 obo:CL_0010017)

# Class: obo:CL_0000366 (obsolete sperm cell (sensu Viridiplantae))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000366 "Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of male germ unit.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000366 obo:PO_0000084)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000366 "gametophyte sperm cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000366 "male gametophyte sperm cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000366 "pollen germ cell")
AnnotationAssertion(rdfs:label obo:CL_0000366 "obsolete sperm cell (sensu Viridiplantae)")
AnnotationAssertion(owl:deprecated obo:CL_0000366 "true"^^xsd:boolean)

# Class: obo:CL_0000367 (sheath cell (sensu Nematoda))

AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000367 "glial cell (sensu Nematoda)")
AnnotationAssertion(rdfs:label obo:CL_0000367 "sheath cell (sensu Nematoda)")
SubClassOf(obo:CL_0000367 obo:CL_0000619)

# Class: obo:CL_0000368 (obsolete myrosin cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000368 "Obsolete. Use PO:0000352 from Plant Ontology instead. Cell containing glucosinolates ('mustard oil glucosides') and myrosinases, enzymes hydrolyzing the glucosinolates. Occurs in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000368 obo:PO_0000352)
AnnotationAssertion(rdfs:label obo:CL_0000368 "obsolete myrosin cell")
AnnotationAssertion(owl:deprecated obo:CL_0000368 "true"^^xsd:boolean)

# Class: obo:CL_0000369 (obo:CL_0000369)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000369 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000369 obo:CL_0002372)
AnnotationAssertion(owl:deprecated obo:CL_0000369 "true"^^xsd:boolean)

# Class: obo:CL_0000370 (obsolete transfer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000370 "Obsolete. Use PO:0000078 from Plant Ontology instead. Parenchyma cell with the wall ingrowth (or invaginations) that increase the surface of the plasmalemma. Appears to be specialized for short-distance transfer of solutes.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000370 obo:PO_0000078)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000370 "intermediary cell")
AnnotationAssertion(rdfs:label obo:CL_0000370 "obsolete transfer cell")
AnnotationAssertion(owl:deprecated obo:CL_0000370 "true"^^xsd:boolean)

# Class: obo:CL_0000371 (protoplast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000371 "The cell protoplasm after removal of the cell wall.")
AnnotationAssertion(obo:RO_0002161 obo:CL_0000371 obo:NCBITaxon_33208)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000371 "MESH:D011523")
AnnotationAssertion(rdfs:label obo:CL_0000371 "protoplast")
SubClassOf(obo:CL_0000371 obo:CL_0000578)

# Class: obo:CL_0000372 (tormogen cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:978-0801481253") obo:IAO_0000115 obo:CL_0000372 "An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization that forms a socket around the base of a cuticular specialization produced by a trichogen cell.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:978-0801481253") oboInOwl:hasBroadSynonym obo:CL_0000372 "socket cell")
AnnotationAssertion(rdfs:label obo:CL_0000372 "tormogen cell")
SubClassOf(obo:CL_0000372 obo:CL_0000463)

# Class: obo:CL_0000373 (histoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2022.01.045") obo:IAO_0000115 obo:CL_0000373 "A progenitor cell found in the larval epidermis of insects and that gives rise to the adult abdominal epidermis.")
AnnotationAssertion(rdfs:label obo:CL_0000373 "histoblast")
SubClassOf(obo:CL_0000373 obo:CL_0011026)
SubClassOf(obo:CL_0000373 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))

# Class: obo:CL_0000374 (trichogen cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:978-0801481253") obo:IAO_0000115 obo:CL_0000374 "An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization, often in the form of a hair, bristle, peg or scale. The base of this specialization is often surrounded by a socket produced by a closely associated tormogen cell.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000374 "hair cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000374 "BTO:0004744")
AnnotationAssertion(rdfs:label obo:CL_0000374 "trichogen cell")
SubClassOf(obo:CL_0000374 obo:CL_0000463)

# Class: obo:CL_0000375 (obsolete osteoprogenitor cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000375 obo:CL_0007010)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000375 "BTO:0002051")
AnnotationAssertion(rdfs:label obo:CL_0000375 "obsolete osteoprogenitor cell")
AnnotationAssertion(owl:deprecated obo:CL_0000375 "true"^^xsd:boolean)

# Class: obo:CL_0000376 (humidity receptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000376 "humidity receptor cell")
SubClassOf(obo:CL_0000376 obo:CL_0000006)

# Class: obo:CL_0000377 (tracheoblast)

AnnotationAssertion(rdfs:label obo:CL_0000377 "tracheoblast")
SubClassOf(obo:CL_0000377 obo:CL_0000069)

# Class: obo:CL_0000378 (supporting cell (sensu Nematoda and Protostomia))

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000378 "support cell (sensu Nematoda and Protostomia)")
AnnotationAssertion(rdfs:label obo:CL_0000378 "supporting cell (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000378 obo:CL_0000630)

# Class: obo:CL_0000379 (sensory processing neuron)

AnnotationAssertion(rdfs:label obo:CL_0000379 "sensory processing neuron")
SubClassOf(obo:CL_0000379 obo:CL_0000540)
SubClassOf(obo:CL_0000379 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))
SubClassOf(obo:CL_0000379 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050893))

# Class: obo:CL_0000380 (thecogen cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Fbbt:00005173") obo:IAO_0000115 obo:CL_0000380 "The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000380 "fly sheath cell")
AnnotationAssertion(rdfs:label obo:CL_0000380 "thecogen cell")
SubClassOf(obo:CL_0000380 obo:CL_0000378)

# Class: obo:CL_0000381 (obsolete neurosecretory neuron)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000381 <https://github.com/obophenotype/cell-ontology/issues/1784>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000381 obo:CL_0000165)
AnnotationAssertion(rdfs:comment obo:CL_0000381 "'neuroendocrine cell' (which has exact synonym \"neurosecretory cell\") and 'neurosecretory neuron' may all refer to the same cell type.")
AnnotationAssertion(rdfs:label obo:CL_0000381 "obsolete neurosecretory neuron")
AnnotationAssertion(owl:deprecated obo:CL_0000381 "true"^^xsd:boolean)

# Class: obo:CL_0000382 (scolopale cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50012-2") Annotation(oboInOwl:hasDbXref "doi:10.1017/CBO9780511818202.024") obo:IAO_0000115 obo:CL_0000382 "A cell that is part of a scolopidium and surrounds the dendrite of a scolopidial neuron.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:978-087969828-7") oboInOwl:hasExactSynonym obo:CL_0000382 "scolopidial sheath cell")
AnnotationAssertion(rdfs:label obo:CL_0000382 "scolopale cell")
SubClassOf(obo:CL_0000382 obo:CL_0000378)
SubClassOf(obo:CL_0000382 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001038))

# Class: obo:CL_0000383 (nephrogenic mesenchyme stem cell)

AnnotationAssertion(rdfs:label obo:CL_0000383 "nephrogenic mesenchyme stem cell")
SubClassOf(obo:CL_0000383 obo:CL_0000134)
SubClassOf(obo:CL_0000383 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000384 (ligament cell)

AnnotationAssertion(rdfs:label obo:CL_0000384 "ligament cell")
SubClassOf(obo:CL_0000384 obo:CL_0000630)

# Class: obo:CL_0000385 (prohemocyte (sensu Nematoda and Protostomia))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000385 "A precursor of mature hemocytes.")
AnnotationAssertion(obo:RO_0002161 obo:CL_0000385 obo:NCBITaxon_33511)
AnnotationAssertion(rdfs:label obo:CL_0000385 "prohemocyte (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000385 obo:CL_0008001)

# Class: obo:CL_0000386 (obsolete attachment cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000386 <https://github.com/obophenotype/cell-ontology/issues/3016>)
AnnotationAssertion(rdfs:comment obo:CL_0000386 "The obsoleted term is redundant")
AnnotationAssertion(rdfs:label obo:CL_0000386 "obsolete attachment cell")
AnnotationAssertion(owl:deprecated obo:CL_0000386 "true"^^xsd:boolean)

# Class: obo:CL_0000387 (hemocyte (sensu Arthropoda))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000387 "A blood cell of the circulatory system of arthropods.")
AnnotationAssertion(rdfs:label obo:CL_0000387 "hemocyte (sensu Arthropoda)")
SubClassOf(obo:CL_0000387 obo:CL_0000390)
SubClassOf(obo:CL_0000387 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))
SubClassOf(obo:CL_0000387 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000385))

# Class: obo:CL_0000388 (tendon cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:37894875") Annotation(oboInOwl:hasDbXref "PMID:957445") obo:IAO_0000115 obo:CL_0000388 "An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000388 "muscle attachment cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000388 "tenocyte")
AnnotationAssertion(rdfs:label obo:CL_0000388 "tendon cell")
EquivalentClasses(obo:CL_0000388 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000043)))

# Class: obo:CL_0000389 (socket cell (sensu Nematoda))

AnnotationAssertion(rdfs:label obo:CL_0000389 "socket cell (sensu Nematoda)")
SubClassOf(obo:CL_0000389 obo:CL_0000619)
SubClassOf(obo:CL_0000389 obo:CL_0000658)

# Class: obo:CL_0000390 (blood cell (sensu Nematoda and Protostomia))

AnnotationAssertion(obo:RO_0002161 obo:CL_0000390 obo:NCBITaxon_33511)
AnnotationAssertion(rdfs:label obo:CL_0000390 "blood cell (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000390 obo:CL_0000081)

# Class: obo:CL_0000391 (obsolete podocyte (sensu Diptera))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000391 <https://github.com/obophenotype/cell-ontology/issues/1949>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000391 obo:CL_0000394)
AnnotationAssertion(rdfs:comment obo:CL_0000391 "Obsoleted as podocytes are not a distinct cell type from plasmatocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000391 "obsolete podocyte (sensu Diptera)")
AnnotationAssertion(owl:deprecated obo:CL_0000391 "true"^^xsd:boolean)

# Class: obo:CL_0000392 (crystal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000392 "A hemocyte that synthesizes and secretes melanins as part of the antimicrobial immune response. It is characterized morphologically by crystal inclusions of phenoloxidases in its cytoplasm, hence its name.")
AnnotationAssertion(rdfs:label obo:CL_0000392 "crystal cell")
SubClassOf(obo:CL_0000392 obo:CL_0000387)
SubClassOf(obo:CL_0000392 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000395))

# Class: obo:CL_0000393 (electrically responsive cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000393 "A cell whose function is determined by its response to an electric signal.")
AnnotationAssertion(rdfs:label obo:CL_0000393 "electrically responsive cell")
SubClassOf(obo:CL_0000393 obo:CL_0000211)

# Class: obo:CL_0000394 (plasmatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000394 "A phagocytic hemocyte, responsible for the engulfment of small particles, microbes, and apoptotic tissue debris. It may also secretes antimicrobial peptides and contribute to the production and secretion of proteins of the hemolymph.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000394 "macrophage")
AnnotationAssertion(rdfs:label obo:CL_0000394 "plasmatocyte")
SubClassOf(obo:CL_0000394 obo:CL_0000387)
SubClassOf(obo:CL_0000394 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035010))

# Class: obo:CL_0000395 (procrystal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000395 "A precursor of mature crystal cells.")
AnnotationAssertion(rdfs:label obo:CL_0000395 "procrystal cell")
SubClassOf(obo:CL_0000395 obo:CL_0000385)

# Class: obo:CL_0000396 (lamellocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50008-0") obo:IAO_0000115 obo:CL_0000396 "A hemocyte found in immuno-stimulated larvae.")
AnnotationAssertion(rdfs:label obo:CL_0000396 "lamellocyte")
SubClassOf(obo:CL_0000396 obo:CL_0000387)

# Class: obo:CL_0000397 (ganglion interneuron)

AnnotationAssertion(rdfs:label obo:CL_0000397 "ganglion interneuron")
EquivalentClasses(obo:CL_0000397 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000045)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000397 obo:CL_0000099)

# Class: obo:CL_0000398 (obsolete polygonal cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000398 <https://github.com/obophenotype/cell-ontology/issues/1949>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000398 obo:CL_0000385)
AnnotationAssertion(rdfs:comment obo:CL_0000398 "Obsoleted as this is actually the same thing as prohemocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000398 "obsolete polygonal cell")
AnnotationAssertion(owl:deprecated obo:CL_0000398 "true"^^xsd:boolean)

# Class: obo:CL_0000399 (obsolete phloem element)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000399 "Obsolete. Consult Plant Ontology instead. OBSOLETED, not defined prior to obsoletion.")
AnnotationAssertion(rdfs:label obo:CL_0000399 "obsolete phloem element")
AnnotationAssertion(owl:deprecated obo:CL_0000399 "true"^^xsd:boolean)

# Class: obo:CL_0000400 (obsolete pavement cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:087694289") obo:IAO_0000115 obo:CL_0000400 "Obsolete. Use PO:0000332 from Plant Ontology instead. An epidermal cell with a characteristic convoluted anticlinal cell wall that gives a jigsaw like appearance to the lamina.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000400 obo:PO_0000332)
AnnotationAssertion(rdfs:label obo:CL_0000400 "obsolete pavement cell")
AnnotationAssertion(owl:deprecated obo:CL_0000400 "true"^^xsd:boolean)

# Class: obo:CL_0000401 (obsolete macrophage (sensu Diptera))

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000401 <https://github.com/obophenotype/cell-ontology/issues/1949>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000401 obo:CL_0000394)
AnnotationAssertion(rdfs:comment obo:CL_0000401 "Obsoleted as plasmatocytes are the macrophages (phagocytic cells) of Diptera.")
AnnotationAssertion(rdfs:label obo:CL_0000401 "obsolete macrophage (sensu Diptera)")
AnnotationAssertion(owl:deprecated obo:CL_0000401 "true"^^xsd:boolean)

# Class: obo:CL_0000402 (obsolete CNS interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-0-12-817424-1.00001-X") obo:IAO_0000115 obo:CL_0000402 "OBSOLETE. An interneuron that has its cell body in a central nervous system.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000402 <https://github.com/obophenotype/cell-ontology/issues/2869>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000402 obo:CL_0000099)
AnnotationAssertion(rdfs:comment obo:CL_0000402 "Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system.")
AnnotationAssertion(rdfs:label obo:CL_0000402 "obsolete CNS interneuron")
AnnotationAssertion(owl:deprecated obo:CL_0000402 "true"^^xsd:boolean)

# Class: obo:CL_0000403 (obo:CL_0000403)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000403 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000403 obo:CL_0000850)
AnnotationAssertion(owl:deprecated obo:CL_0000403 "true"^^xsd:boolean)

# Class: obo:CL_0000404 (electrically signaling cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000404 "A cell that initiates an electrical signal and passes that signal to another cell.")
AnnotationAssertion(rdfs:label obo:CL_0000404 "electrically signaling cell")
SubClassOf(obo:CL_0000404 obo:CL_0000211)

# Class: obo:CL_0000405 (obsolete neuroepidermoblast)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000405 <https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621>)
AnnotationAssertion(rdfs:comment obo:CL_0000405 "Obsoleted as the term seems completely unused in the literature.")
AnnotationAssertion(rdfs:label obo:CL_0000405 "obsolete neuroepidermoblast")
AnnotationAssertion(owl:deprecated obo:CL_0000405 "true"^^xsd:boolean)

# Class: obo:CL_0000406 (CNS short range interneuron)

AnnotationAssertion(rdfs:label obo:CL_0000406 "CNS short range interneuron")
SubClassOf(obo:CL_0000406 obo:CL_0000099)

# Class: obo:CL_0000407 (scolopidial ligament cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-0-12-408088-1.00002-6") Annotation(oboInOwl:hasDbXref "doi:10.1023/a:1018564904170") obo:IAO_0000115 obo:CL_0000407 "A cell that anchors the cell body of a scolopidial neuron to the integument.")
AnnotationAssertion(rdfs:label obo:CL_0000407 "scolopidial ligament cell")
SubClassOf(obo:CL_0000407 obo:CL_0000378)
SubClassOf(obo:CL_0000407 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001038))

# Class: obo:CL_0000408 (male gamete)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000408 "BTO:0001277")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000408 "CALOHA:TS-0949")
AnnotationAssertion(rdfs:label obo:CL_0000408 "male gamete")
EquivalentClasses(obo:CL_0000408 ObjectIntersectionOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009566)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000408 obo:CL_0000015)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000408 obo:CL_0000300)

# Class: obo:CL_0000409 (obsolete scolopidial sheath cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000409 obo:CL_0000382)
AnnotationAssertion(rdfs:comment obo:CL_0000409 "Obsoleted as this refers to the same cell type as 'scolopale cell'.")
AnnotationAssertion(rdfs:label obo:CL_0000409 "obsolete scolopidial sheath cell")
AnnotationAssertion(owl:deprecated obo:CL_0000409 "true"^^xsd:boolean)

# Class: obo:CL_0000410 (CNS long range interneuron)

AnnotationAssertion(rdfs:label obo:CL_0000410 "CNS long range interneuron")
SubClassOf(obo:CL_0000410 obo:CL_0000099)

# Class: obo:CL_0000411 (Caenorhabditis hypodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.wormatlas.org/hermaphrodite/hypodermis/mainframe.htm") obo:IAO_0000115 obo:CL_0000411 "An epithelial cell of the hypodermis of Caenorhabditis.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000411 "roundworm hypodermal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000411 "WBbt:0007846")
AnnotationAssertion(rdfs:comment obo:CL_0000411 "This term was originally added to CL for parity with the Worm anatomy ontology, which is dedicated to C elegans. It is not clear if it makes sense to try and generalize the concept and include in CL, and this term may be obsoleted in future. Note there is no similarity to the hypodermis in vertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0000411 "Caenorhabditis hypodermal cell")
SubClassOf(obo:CL_0000411 obo:CL_0000066)
SubClassOf(obo:CL_0000411 obo:CL_0000228)
SubClassOf(obo:CL_0000411 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6237))

# Class: obo:CL_0000412 (polyploid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "PMID:32646579") Annotation(oboInOwl:hasDbXref "https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy"^^xsd:anyURI) obo:IAO_0000115 obo:CL_0000412 "A cell that contains more than two haploid sets of chromosomes.")
AnnotationAssertion(rdfs:label obo:CL_0000412 "polyploid cell")
EquivalentClasses(obo:CL_0000412 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001377)))

# Class: obo:CL_0000413 (haploid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000413 "A cell whose nucleus contains a single haploid genome.")
AnnotationAssertion(rdfs:label obo:CL_0000413 "haploid cell")
EquivalentClasses(obo:CL_0000413 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375)))

# Class: obo:CL_0000414 (obsolete cell by ploidy)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000414 "OBSOLETE: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei.")
AnnotationAssertion(oboInOwl:consider obo:CL_0000414 "CL:0000000")
AnnotationAssertion(oboInOwl:consider obo:CL_0000414 "CL:0000003")
AnnotationAssertion(oboInOwl:consider obo:CL_0000414 "CL:0000255")
AnnotationAssertion(oboInOwl:consider obo:CL_0000414 "CL:0001034")
AnnotationAssertion(rdfs:comment obo:CL_0000414 "This term was made obsolete because there is no difference in meaning between it and 'cell', as any cell with chromosomes can be classified by its ploidy. If you have used this term in annotation, please replace it with cell (CL:0000000), native cell (CL:0000003), eukaryotic cell (CL:0000255) or cell in vitro (CL:0001034) as appropriate.")
AnnotationAssertion(rdfs:label obo:CL_0000414 "obsolete cell by ploidy")
AnnotationAssertion(owl:deprecated obo:CL_0000414 "true"^^xsd:boolean)

# Class: obo:CL_0000415 (diploid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000415 "A cell whose nucleus has two haploid genomes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000415 "FMA:72300")
AnnotationAssertion(rdfs:label obo:CL_0000415 "diploid cell")
SubClassOf(obo:CL_0000415 obo:CL_0000000)

# Class: obo:CL_0000416 (polytene cell)

AnnotationAssertion(rdfs:label obo:CL_0000416 "polytene cell")
SubClassOf(obo:CL_0000416 obo:CL_0000412)

# Class: obo:CL_0000417 (endopolyploid cell)

AnnotationAssertion(rdfs:label obo:CL_0000417 "endopolyploid cell")
SubClassOf(obo:CL_0000417 obo:CL_0000412)

# Class: obo:CL_0000418 (arcade cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.wormatlas.org/ver1/handbook/hypodermis/hypsupportother.htm#arcadecells") obo:IAO_0000115 obo:CL_0000418 "An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000418 "WBbt:0005793")
AnnotationAssertion(rdfs:label obo:CL_0000418 "arcade cell")
SubClassOf(obo:CL_0000418 obo:CL_0000066)
SubClassOf(obo:CL_0000418 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6237))

# Class: obo:CL_0000419 (seam cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.wormatlas.org/hermaphrodite/seam%20cells/mainframe.htm") obo:IAO_0000115 obo:CL_0000419 "An epithelial fate stem cell found in flatworms.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000419 "BTO:0003039")
AnnotationAssertion(rdfs:label obo:CL_0000419 "seam cell")
SubClassOf(obo:CL_0000419 obo:CL_0000036)

# Class: obo:CL_0000420 (syncytial epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000420 "An epithelial cell that forms a syncytium, which is a multinucleated cell resulting from the fusion of multiple cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000420 "Wikipedia:Syncytium")
AnnotationAssertion(rdfs:label obo:CL_0000420 "syncytial epithelial cell")
SubClassOf(obo:CL_0000420 obo:CL_0000066)
SubClassOf(obo:CL_0000420 obo:CL_0000228)
SubClassOf(obo:CL_0000420 obo:CL_4052002)

# Class: obo:CL_0000421 (coelomocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000421 "A free floating cell, including amebocytes and eleocytes, in the coelom of certain animals, especially annelids.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000421 "BTO:0002856")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000421 "WBbt:0005751")
AnnotationAssertion(rdfs:label obo:CL_0000421 "coelomocyte")
SubClassOf(obo:CL_0000421 obo:CL_0000080)
SubClassOf(obo:CL_0000421 obo:CL_0000519)

# Class: obo:CL_0000422 (mitogenic signaling cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000422 "A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment.")
AnnotationAssertion(rdfs:label obo:CL_0000422 "mitogenic signaling cell")
SubClassOf(obo:CL_0000422 obo:CL_0000000)

# Class: obo:CL_0000423 (tip cell)

AnnotationAssertion(rdfs:label obo:CL_0000423 "tip cell")
SubClassOf(obo:CL_0000423 obo:CL_0000422)

# Class: obo:CL_0000424 (excretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") obo:IAO_0000115 obo:CL_0000424 "A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000424 "WBbt:0005812")
AnnotationAssertion(rdfs:label obo:CL_0000424 "excretory cell")
SubClassOf(obo:CL_0000424 obo:CL_0000000)

# Class: obo:CL_0000425 (pore cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000425 "Forms the terminal part of the cuticle-lined excretory duct of C. elegans.")
AnnotationAssertion(rdfs:label obo:CL_0000425 "pore cell")
SubClassOf(obo:CL_0000425 obo:CL_0000658)

# Class: obo:CL_0000426 (obsolete scaffold cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000426 <https://github.com/obophenotype/cell-ontology/issues/708>)
AnnotationAssertion(rdfs:comment obo:CL_0000426 "This is a cell used in tissue engineering and is out of scope for CL.")
AnnotationAssertion(rdfs:label obo:CL_0000426 "obsolete scaffold cell")
AnnotationAssertion(owl:deprecated obo:CL_0000426 "true"^^xsd:boolean)

# Class: obo:CL_0000427 (GLR cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://wormatlas.psc.edu/hermaphrodite/muscleGLR/mainframe.htm") obo:IAO_0000115 obo:CL_0000427 "A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role.")
AnnotationAssertion(rdfs:label obo:CL_0000427 "GLR cell")
SubClassOf(obo:CL_0000427 obo:CL_0002320)

# Class: obo:CL_0000428 (yolk cell)

AnnotationAssertion(rdfs:label obo:CL_0000428 "yolk cell")
SubClassOf(obo:CL_0000428 obo:CL_0000325)
SubClassOf(obo:CL_0000428 obo:CL_0000349)

# Class: obo:CL_0000429 (imaginal disc cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/s00412-016-0595-4") obo:IAO_0000115 obo:CL_0000429 "A columnar epithelial cell that is part of an insect imaginal disc.")
AnnotationAssertion(rdfs:comment obo:CL_0000429 "This term does not encompass all the cell types that may be found in an epithelial disc (such as the peripodial or adepithelial cells), only the cells that form the disc epithelium proper.")
AnnotationAssertion(rdfs:label obo:CL_0000429 "imaginal disc cell")
SubClassOf(obo:CL_0000429 obo:CL_0000146)
SubClassOf(obo:CL_0000429 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000939))
SubClassOf(obo:CL_0000429 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))

# Class: obo:CL_0000430 (xanthophore cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000430 "A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000430 "xanthophore")
AnnotationAssertion(rdfs:label obo:CL_0000430 "xanthophore cell")
SubClassOf(obo:CL_0000430 obo:CL_0000147)
SubClassOf(obo:CL_0000430 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005002))

# Class: obo:CL_0000431 (iridophore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000431 "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platelets or iridisomes. The color-generating components produce a silver, gold, or iridescent color.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000431 "guanophore")
AnnotationAssertion(rdfs:label obo:CL_0000431 "iridophore")
SubClassOf(obo:CL_0000431 obo:CL_0000147)
SubClassOf(obo:CL_0000431 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005001))

# Class: obo:CL_0000432 (reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Reticular_cell") obo:IAO_0000115 obo:CL_0000432 "A fibroblast that synthesizes collagen and uses it to produce reticular fibers, thus providing structural support. Reticular cells are found in many organs, including the spleen, lymph nodes and kidneys. Subtypes of reticular cells include epithelial, mesenchymal, and fibroblastic reticular cells. Fibroblastic reticular cells are involved in directing B cells and T cells to specific regions within a tissue, whereas epithelial and mesenchymal reticular cells are associated with certain areas of the brain.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000432 "FMA:62877")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000432 "reticulum cell")
AnnotationAssertion(rdfs:label obo:CL_0000432 "reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0000432 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0000432 obo:CL_0000057)

# Class: obo:CL_0000433 (obsolete functional megaspore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000433 "Obsolete. Use PO:0000244 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that will undergo megagametogenesis.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000433 obo:PO_0000244)
AnnotationAssertion(rdfs:label obo:CL_0000433 "obsolete functional megaspore")
AnnotationAssertion(owl:deprecated obo:CL_0000433 "true"^^xsd:boolean)

# Class: obo:CL_0000434 (eccrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0198547684") obo:IAO_0000115 obo:CL_0000434 "A secretory cell that discharges its product without loss of cytoplasm.")
AnnotationAssertion(rdfs:label obo:CL_0000434 "eccrine cell")
SubClassOf(obo:CL_0000434 obo:CL_0000066)
SubClassOf(obo:CL_0000434 obo:CL_0000151)

# Class: obo:CL_0000435 (alkali secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000435 "alkali secreting cell")
SubClassOf(obo:CL_0000435 obo:CL_0000151)

# Class: obo:CL_0000436 (vaginal lubricant secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000436 "vaginal lubricant secreting cell")
SubClassOf(obo:CL_0000436 obo:CL_0000151)
SubClassOf(obo:CL_0000436 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000996))

# Class: obo:CL_0000437 (gonadtroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Gonadotroph") obo:IAO_0000115 obo:CL_0000437 "A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000437 "BTO:0002482")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000437 "FMA:83100")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "delta basophil")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "follicle stimulating hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "gonadotrope")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "gonadotrope cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "gonadotroph")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "gonadotropic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000437 "pituitary delta cell")
AnnotationAssertion(rdfs:label obo:CL_0000437 "gonadtroph")
SubClassOf(obo:CL_0000437 obo:CL_0000438)
SubClassOf(obo:CL_0000437 obo:CL_0000639)

# Class: obo:CL_0000438 (luteinizing hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000438 "A peptide hormone secreting cell pituitary that produces luteinizing hormone.")
AnnotationAssertion(rdfs:label obo:CL_0000438 "luteinizing hormone secreting cell")
EquivalentClasses(obo:CL_0000438 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032275)))

# Class: obo:CL_0000439 (prolactin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000439 "A peptide hormone cell that secretes prolactin.")
AnnotationAssertion(rdfs:label obo:CL_0000439 "prolactin secreting cell")
EquivalentClasses(obo:CL_0000439 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070459)))

# Class: obo:CL_0000440 (melanocyte stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000440 "A cell of the intermediate pituitary that produces melanocyte stimulating hormone.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000440 "BTO:0002277")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000440 "melanotrope")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000440 "melanotroph")
AnnotationAssertion(rdfs:label obo:CL_0000440 "melanocyte stimulating hormone secreting cell")
EquivalentClasses(obo:CL_0000440 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036160)))

# Class: obo:CL_0000441 (follicle stem cell (sensu Arthropoda))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/B978-012369493-5.50005-5") Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-020-19361-0") Annotation(oboInOwl:hasDbXref "doi:10.1242/dev.121.11.3797") obo:IAO_0000115 obo:CL_0000441 "A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.devcel.2005.08.012") oboInOwl:hasBroadSynonym obo:CL_0000441 "somatic stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000441 "follicle stem cell (sensu Arthropoda)")
SubClassOf(obo:CL_0000441 obo:CL_0000036)
SubClassOf(Annotation(obo:IAO_0000233 "https://github.com/obophenotype/cell-ontology/issues/1943") obo:CL_0000441 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))

# Class: obo:CL_0000442 (follicular dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:127520252") obo:IAO_0000115 obo:CL_0000442 "A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000442 "BTO:0004267")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000442 "FMA:83037")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000442 "MESH:D020566")
AnnotationAssertion(rdfs:comment obo:CL_0000442 "Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451.")
AnnotationAssertion(rdfs:label obo:CL_0000442 "follicular dendritic cell")
SubClassOf(obo:CL_0000442 obo:CL_0000451)

# Class: obo:CL_0000443 (calcitonin secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000443 "calcitonin secreting cell")
EquivalentClasses(obo:CL_0000443 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036161)))

# Class: obo:CL_0000444 (obliquely striated muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:DOS") Annotation(oboInOwl:hasDbXref "PMID:8720463") obo:IAO_0000115 obo:CL_0000444 "A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern.")
AnnotationAssertion(rdfs:comment obo:CL_0000444 "Examples include the somatic muscles of nemotodes and cephalopods.")
AnnotationAssertion(rdfs:label obo:CL_0000444 "obliquely striated muscle cell")
EquivalentClasses(obo:CL_0000444 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002479)))

# Class: obo:CL_0000445 (apoptosis fated cell)

AnnotationAssertion(rdfs:label obo:CL_0000445 "apoptosis fated cell")
SubClassOf(obo:CL_0000445 obo:CL_0000000)

# Class: obo:CL_0000446 (chief cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69078") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0000446 "An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000446 "BTO:0004712")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000446 "CALOHA:TS-2140")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000446 "FMA:69078")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "parathyroid chief cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "parathyroid gland chief cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "parathyroid hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "principal cell of parathyroid gland")
AnnotationAssertion(rdfs:label obo:CL_0000446 "chief cell of parathyroid gland")
SubClassOf(obo:CL_0000446 obo:CL_0000066)
SubClassOf(obo:CL_0000446 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011197))
SubClassOf(obo:CL_0000446 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035898))

# Class: obo:CL_0000447 (carbohydrate secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000447 "carbohydrate secreting cell")
SubClassOf(obo:CL_0000447 obo:CL_0000151)

# Class: obo:CL_0000448 (white adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D052438") obo:IAO_0000115 obo:CL_0000448 "An adipocyte with light coloration and few mitochondria. It contains a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000448 "CALOHA:TS-1119")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000448 "FMA:83434")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000448 "white adipose cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000448 "white fat cell")
AnnotationAssertion(rdfs:label obo:CL_0000448 "white adipocyte")
SubClassOf(obo:CL_0000448 obo:CL_0000136)
SubClassOf(obo:CL_0000448 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001347))
SubClassOf(obo:CL_0000448 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002334))

# Class: obo:CL_0000449 (brown adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D002001") obo:IAO_0000115 obo:CL_0000449 "A cell from the thermogenic form of adipose tissue found in many species,  particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000449 "CALOHA:TS-0099")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000449 "FMA:83435")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000449 "brown adipose cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000449 "brown fat cell")
AnnotationAssertion(rdfs:label obo:CL_0000449 "brown adipocyte")
SubClassOf(obo:CL_0000449 obo:CL_0000136)
SubClassOf(obo:CL_0000449 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001348))
SubClassOf(obo:CL_0000449 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002335))

# Class: obo:CL_0000450 (obo:CL_0000450)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000450 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000450 obo:CL_0000136)
AnnotationAssertion(owl:deprecated obo:CL_0000450 "true"^^xsd:boolean)

# Class: obo:CL_0000451 (dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000451 "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000451 "BTO:0002042")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000451 "CALOHA:TS-0194")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000451 "FMA:83036")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000451 "MESH:D003713")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000451 "interdigitating cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000451 "veiled cell")
AnnotationAssertion(rdfs:label obo:CL_0000451 "dendritic cell")
EquivalentClasses(obo:CL_0000451 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045580)))
SubClassOf(obo:CL_0000451 obo:CL_0000113)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000451 obo:CL_0000738)
DisjointClasses(obo:CL_0000451 obo:CL_0000542)

# Class: obo:CL_0000452 (obsolete thyroid hormone secreting cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000452 <https://github.com/obophenotype/cell-ontology/issues/3161>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000452 obo:CL_0002258)
AnnotationAssertion(rdfs:comment obo:CL_0000452 "This term is redundant and has been merged with thyroid follicular cell")
AnnotationAssertion(rdfs:label obo:CL_0000452 "obsolete thyroid hormone secreting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000452 "true"^^xsd:boolean)

# Class: obo:CL_0000453 (Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000453 "Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000453 "BTO:0000705")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000453 "CALOHA:TS-2375")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000453 "FMA:63072")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000453 "MESH:D007801")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000453 "LC")
AnnotationAssertion(rdfs:comment obo:CL_0000453 "Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.")
AnnotationAssertion(rdfs:label obo:CL_0000453 "Langerhans cell")
EquivalentClasses(obo:CL_0000453 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001293) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002828)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000453 obo:CL_0000990)
SubClassOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000763))

# Class: obo:CL_0000454 (epinephrine secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12438093") obo:IAO_0000115 obo:CL_0000454 "A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0048242") oboInOwl:hasExactSynonym obo:CL_0000454 "adrenaline secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000454 "epinephrin secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000454 "epinephrine secreting cell")
EquivalentClasses(obo:CL_0000454 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048242)))
SubClassOf(obo:CL_0000454 obo:CL_0000457)

# Class: obo:CL_0000455 (obsolete starch sheath cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:044174520") obo:IAO_0000115 obo:CL_0000455 "Obsolete. Use PO:0004531 from Plant Ontology instead. A cell characterized by conspicuous and rather stable accumulation of starch.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000455 obo:PO_0004531)
AnnotationAssertion(rdfs:label obo:CL_0000455 "obsolete starch sheath cell")
AnnotationAssertion(owl:deprecated obo:CL_0000455 "true"^^xsd:boolean)

# Class: obo:CL_0000456 (mineralocorticoid secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000456 "mineralocorticoid secreting cell")
EquivalentClasses(obo:CL_0000456 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035931)))

# Class: obo:CL_0000457 (biogenic amine secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000457 "biogenic amine secreting cell")
SubClassOf(obo:CL_0000457 obo:CL_0000151)

# Class: obo:CL_0000458 (serotonin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19630576") obo:IAO_0000115 obo:CL_0000458 "A cell type that secretes 5-Hydroxytryptamine (serotonin).")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000458 "5-HT secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000458 "5-Hydroxytryptamine secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000458 "serotonin secreting cell")
EquivalentClasses(obo:CL_0000458 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820)))
SubClassOf(obo:CL_0000458 obo:CL_0000457)

# Class: obo:CL_0000459 (noradrenergic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0000459 "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000459 "noradrenaline secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000459 "norepinephrin secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000459 "norepinephrine secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000459 "noradrenergic cell")
EquivalentClasses(obo:CL_0000459 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048243)))
SubClassOf(obo:CL_0000459 obo:CL_0000457)

# Class: obo:CL_0000460 (glucocorticoid secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000460 "glucocorticoid secreting cell")
EquivalentClasses(obo:CL_0000460 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035933)))

# Class: obo:CL_0000461 (obo:CL_0000461)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000461 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000461 obo:CL_0000648)
AnnotationAssertion(owl:deprecated obo:CL_0000461 "true"^^xsd:boolean)

# Class: obo:CL_0000462 (adepithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/S0925-4773(97)00654-0") obo:IAO_0000115 obo:CL_0000462 "A cell of mesodermal origin that is closely associated with the epithelium of an imaginal disc. It is a precursor of some of the insect's adult muscles.")
AnnotationAssertion(rdfs:label obo:CL_0000462 "adepithelial cell")
SubClassOf(obo:CL_0000462 obo:CL_0000680)
SubClassOf(obo:CL_0000462 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))

# Class: obo:CL_0000463 (epidermal cell (sensu Arthropoda))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FlyBase:ds") Annotation(oboInOwl:hasDbXref "ISBN:ISBN:978-0801481253") obo:IAO_0000115 obo:CL_0000463 "An epidermal cell that secretes chitinous cuticle from its apical side.")
AnnotationAssertion(rdfs:comment obo:CL_0000463 "While insect epidermis is generally columnar/cuboidal, there are certainly well studied cases where it is not (e.g.- Rhodnius prolixus when starved). So it would be safer to add this as a differentium for particular species where this is known. -DSJ.")
AnnotationAssertion(rdfs:label obo:CL_0000463 "epidermal cell (sensu Arthropoda)")
SubClassOf(obo:CL_0000463 obo:CL_0000362)
SubClassOf(obo:CL_0000463 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))
SubClassOf(obo:CL_0000463 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000464))

# Class: obo:CL_0000464 (epidermoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7576311") obo:IAO_0000115 obo:CL_0000464 "An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions.")
AnnotationAssertion(rdfs:label obo:CL_0000464 "epidermoblast")
SubClassOf(obo:CL_0000464 obo:CL_0000710)
SubClassOf(obo:CL_0000464 obo:CL_0011026)
SubClassOf(obo:CL_0000464 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000114))

# Class: obo:CL_0000465 (cardioblast (sensu Arthropoda))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/BF00360522") obo:IAO_0000115 obo:CL_0000465 "A precursor of the cells that form the dorsal vessel of arthropods.")
AnnotationAssertion(rdfs:label obo:CL_0000465 "cardioblast (sensu Arthropoda)")
SubClassOf(obo:CL_0000465 obo:CL_0010021)
SubClassOf(obo:CL_0000465 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))

# Class: obo:CL_0000466 (obo:CL_0000466)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000466 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000466 obo:CL_0000193)
AnnotationAssertion(owl:deprecated obo:CL_0000466 "true"^^xsd:boolean)

# Class: obo:CL_0000467 (adrenocorticotropic hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000467 "A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0051458") oboInOwl:hasExactSynonym obo:CL_0000467 "ACTH secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000467 "adrenocorticotrophic hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000467 "corticotrophin hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000467 "corticotropin hormone secreting cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0051458") oboInOwl:hasExactSynonym obo:CL_0000467 "corticotropin secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000467 "adrenocorticotropic hormone secreting cell")
EquivalentClasses(obo:CL_0000467 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0051458)))

# Class: obo:CL_0000468 (neuroglioblast (sensu Nematoda and Protostomia))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1002/glia.21162") obo:IAO_0000115 obo:CL_0000468 "A precursor of the central nervous system that gives rise to both neurons and glial cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000468 "neuro-glioblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000468 "neuroglioblast")
AnnotationAssertion(rdfs:label obo:CL_0000468 "neuroglioblast (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000468 obo:CL_0000047)
SubClassOf(obo:CL_0000468 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33317))

# Class: obo:CL_0000469 (ganglion mother cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000469 "A neural progenitor cell that is the daughter of a neuroblast (sensu arthopoda).  The progeny of ganglion mother cells develop into neurons, glia and (occasionally) epithelial cells.")
AnnotationAssertion(rdfs:label obo:CL_0000469 "ganglion mother cell")
SubClassOf(obo:CL_0000469 obo:CL_0011020)
SubClassOf(obo:CL_0000469 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000338))

# Class: obo:CL_0000470 (digestive enzyme secreting cell)

AnnotationAssertion(rdfs:label obo:CL_0000470 "digestive enzyme secreting cell")
SubClassOf(obo:CL_0000470 obo:CL_0000154)

# Class: obo:CL_0000471 (obo:CL_0000471)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000471 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000471 obo:CL_0000295)
AnnotationAssertion(owl:deprecated obo:CL_0000471 "true"^^xsd:boolean)

# Class: obo:CL_0000472 (obsolete chlorenchyma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000472 "Obsolete. Use PO:0000076 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. Parenchyma cells containing chloroplasts; a component of leaf mesophyll and other green parenchyma tissue.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000472 obo:PO_0000076)
AnnotationAssertion(rdfs:label obo:CL_0000472 "obsolete chlorenchyma cell")
AnnotationAssertion(owl:deprecated obo:CL_0000472 "true"^^xsd:boolean)

# Class: obo:CL_0000473 (OBSOLETE defensive cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000473 "OBSOLETE: A cell whose primary function is to protect the organism.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000473 <https://github.com/obophenotype/cell-ontology/pull/3056>)
AnnotationAssertion(rdfs:comment obo:CL_0000473 "Unsustainable functional grouping term of dubious utility.")
AnnotationAssertion(rdfs:label obo:CL_0000473 "OBSOLETE defensive cell")
AnnotationAssertion(owl:deprecated obo:CL_0000473 "true"^^xsd:boolean)

# Class: obo:CL_0000474 (pericardial nephrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00003184") Annotation(oboInOwl:hasDbXref "GO:0061320") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") obo:IAO_0000115 obo:CL_0000474 "An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00005058") Annotation(oboInOwl:hasDbXref "GO:0061320") oboInOwl:hasNarrowSynonym obo:CL_0000474 "pericardial cell")
AnnotationAssertion(rdfs:label obo:CL_0000474 "pericardial nephrocyte")
SubClassOf(obo:CL_0000474 obo:CL_0000519)
SubClassOf(obo:CL_0000474 obo:CL_0002520)

# Class: obo:CL_0000475 (obsolete degenerate megaspore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000475 "Obsolete. Use PO:0000245 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that do not participate in megagametogenesis.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000475 obo:PO_0000245)
AnnotationAssertion(rdfs:label obo:CL_0000475 "obsolete degenerate megaspore")
AnnotationAssertion(owl:deprecated obo:CL_0000475 "true"^^xsd:boolean)

# Class: obo:CL_0000476 (thyrotroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000476 "A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000476 "FMA:83099")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000476 "MESH:D052684")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000476 "beta-basophil")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000476 "thyroid stimulating hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000476 "thyrotrope")
AnnotationAssertion(rdfs:label obo:CL_0000476 "thyrotroph")
SubClassOf(obo:CL_0000476 obo:CL_0000639)
SubClassOf(obo:CL_0000476 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070460))

# Class: obo:CL_0000477 (follicle cell of egg chamber)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000477 "A somatic epithelial cell of the insect egg chamber.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000477 "follicle cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000477 "ovarian follicle cell")
AnnotationAssertion(rdfs:label obo:CL_0000477 "follicle cell of egg chamber")
SubClassOf(obo:CL_0000477 obo:CL_0000500)
SubClassOf(obo:CL_0000477 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992))
SubClassOf(Annotation(oboInOwl:source <https://github.com/obophenotype/cell-ontology/issues/589>) obo:CL_0000477 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))
SubClassOf(obo:CL_0000477 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000441))

# Class: obo:CL_0000478 (oxytocin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000478 "A peptide hormone secreting cell that secretes oxytocin stimulating hormone")
AnnotationAssertion(rdfs:label obo:CL_0000478 "oxytocin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000478 obo:CL_0000167)

# Class: obo:CL_0000479 (vasopressin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000479 "A peptide hormone secreting cell that secretes vasopressin stimulating hormone")
AnnotationAssertion(rdfs:label obo:CL_0000479 "vasopressin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000479 obo:CL_0000167)

# Class: obo:CL_0000480 (secretin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000480 "A peptide hormone secreting cell that secretes secretin stimulating hormone")
AnnotationAssertion(rdfs:label obo:CL_0000480 "secretin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000480 obo:CL_0000167)

# Class: obo:CL_0000481 (cholecystokin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000481 "A peptide hormone secreting cell that secretes cholecystokin stimulating hormone.")
AnnotationAssertion(rdfs:label obo:CL_0000481 "cholecystokin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000481 obo:CL_0000167)

# Class: obo:CL_0000482 (juvenile hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000482 "An endocrine cell that secretes juvenile hormone.")
AnnotationAssertion(rdfs:label obo:CL_0000482 "juvenile hormone secreting cell")
EquivalentClasses(obo:CL_0000482 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045443)))

# Class: obo:CL_0000483 (bombesin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000483 "A peptide hormone secreting cell that secretes bombesin stimulating hormone.")
AnnotationAssertion(rdfs:label obo:CL_0000483 "bombesin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000483 obo:CL_0000167)

# Class: obo:CL_0000484 (connective tissue type mast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19923473") Annotation(oboInOwl:hasDbXref "PMID:9354811") obo:IAO_0000115 obo:CL_0000484 "Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000484 "MC(TC)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000484 "MCTC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000484 "TC mast cells")
AnnotationAssertion(rdfs:comment obo:CL_0000484 "They are CD88-positive. The cytoplasmic granules contain high levels of histamine and heparin (mouse) or major neutral proteases, tryptase, chymase, carboxypeptidase A, and cathepsin G (humans). Reportedly, they cannot produce leukotrienes (LTC4) and IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0000484 "connective tissue type mast cell")
EquivalentClasses(obo:CL_0000484 ObjectIntersectionOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002384)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000484 obo:CL_0000097)

# Class: obo:CL_0000485 (mucosal type mast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:19923473") Annotation(oboInOwl:hasDbXref "PMID:9354811") obo:IAO_0000115 obo:CL_0000485 "Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000485 "MC(T)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000485 "MCT")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000485 "T mast cells")
AnnotationAssertion(rdfs:comment obo:CL_0000485 "They are CD88-negative. The cytoplasmic granules contain low levels of histamine and high levels of chondroitin sulfate (mouse) or major neutral proteases and tryptase (humans). Additionally, they can produce leukotrienes (LTC4), IL-5, IL-6, and low levels of IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0000485 "mucosal type mast cell")
EquivalentClasses(obo:CL_0000485 ObjectIntersectionOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001961) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002540)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000485 obo:CL_0000097)

# Class: obo:CL_0000486 (garland cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") Annotation(oboInOwl:hasDbXref "fbbt:00005059") obo:IAO_0000115 obo:CL_0000486 "A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0061321") oboInOwl:hasBroadSynonym obo:CL_0000486 "garland nephrocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000486 "BTO:0004596")
AnnotationAssertion(rdfs:label obo:CL_0000486 "garland cell")
SubClassOf(obo:CL_0000486 obo:CL_0000227)
SubClassOf(obo:CL_0000486 obo:CL_0000519)
SubClassOf(obo:CL_0000486 obo:CL_0002520)

# Class: obo:CL_0000487 (oenocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:bf") Annotation(oboInOwl:hasDbXref "PMID:11171397") Annotation(oboInOwl:hasDbXref "PMID:24397521") Annotation(oboInOwl:hasDbXref "PMID:34208190") Annotation(oboInOwl:hasDbXref "https://www.merriam-webster.com/dictionary/oenocyte") obo:IAO_0000115 obo:CL_0000487 "A secretory cell of ectodermal origin. This cell may have important functions in fatty acid and hydrocarbon metabolism and is metabolically linked to the fat body and tracheae. This cell is exclusive of arthropods.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24397521") Annotation(oboInOwl:hasDbXref "PMID:34208190") rdfs:comment obo:CL_0000487 "Oenocytes are highly variable in size, shape, cluster formation and anatomical location. In adults, oenocytes tend to be smaller but more numerous than in larvae. While oenocytes have been found in arachnids and crustaceans, they have been most abundantly described in insects.")
AnnotationAssertion(rdfs:label obo:CL_0000487 "oenocyte")
SubClassOf(obo:CL_0000487 obo:CL_0000151)
SubClassOf(obo:CL_0000487 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))

# Class: obo:CL_0000488 (visible light photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000488 "A photoreceptor cell that detects visible light.")
AnnotationAssertion(rdfs:label obo:CL_0000488 "visible light photoreceptor cell")
EquivalentClasses(obo:CL_0000488 ObjectIntersectionOf(obo:CL_0000210 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009584)))
SubClassOf(obo:CL_0000488 obo:CL_0000210)

# Class: obo:CL_0000489 (scotopic photoreceptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000489 "scotopic photoreceptor cell")
SubClassOf(obo:CL_0000489 obo:CL_0000210)

# Class: obo:CL_0000490 (photopic photoreceptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000490 "photopic photoreceptor cell")
SubClassOf(obo:CL_0000490 obo:CL_0000488)

# Class: obo:CL_0000491 (obsolete cytotoxic T cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000491 "OBSOLETE: A cell responsible for spontaneous cytotoxicity of a variety of tumor cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as killer cells (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody.")
AnnotationAssertion(rdfs:comment obo:CL_0000491 "This term had an incorrect definition and was overly broad. Consider using 'cytotoxic T cell ; CL:0000910' (in most cases) or another lymphocyte cell type if cytotoxicity is shown to be part of the cell's phenotype in a particular experimental situation.")
AnnotationAssertion(rdfs:label obo:CL_0000491 "obsolete cytotoxic T cell")
AnnotationAssertion(owl:deprecated obo:CL_0000491 "true"^^xsd:boolean)

# Class: obo:CL_0000492 (CD4-positive helper T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "MESH:D006377") obo:IAO_0000115 obo:CL_0000492 "A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000492 "CALOHA:TS-1146")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000492 "FMA:70572")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive T-helper cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive helper T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive helper T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive helper T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000492 "CD4-positive helper T cell")
EquivalentClasses(obo:CL_0000492 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000492 obo:CL_0000624)
SubClassOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))
SubClassOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))

# Class: obo:CL_0000493 (obsolete regulatory T cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000493 "OBSOLETE: Subpopulation of CD4+ cells which induce CD8+ suppressor T cells to suppress antibody production by B cells. They also stimulate other cellular immune responses.")
AnnotationAssertion(rdfs:comment obo:CL_0000493 "This term was defined too narrowly; consider using the term 'regulatory T cell ; CL:0000815' instead.")
AnnotationAssertion(rdfs:label obo:CL_0000493 "obsolete regulatory T cell")
AnnotationAssertion(owl:deprecated obo:CL_0000493 "true"^^xsd:boolean)

# Class: obo:CL_0000494 (UV sensitive photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000494 "A photoreceptor cell that detects ultraviolet light.")
AnnotationAssertion(rdfs:label obo:CL_0000494 "UV sensitive photoreceptor cell")
EquivalentClasses(obo:CL_0000494 ObjectIntersectionOf(obo:CL_0000210 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009589)))
SubClassOf(obo:CL_0000494 obo:CL_0000210)

# Class: obo:CL_0000495 (blue sensitive photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000495 "A photoreceptor cell that is sensitive to blue light.")
AnnotationAssertion(rdfs:label obo:CL_0000495 "blue sensitive photoreceptor cell")
SubClassOf(obo:CL_0000495 obo:CL_0000490)

# Class: obo:CL_0000496 (green sensitive photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000496 "A photoreceptor cell that is sensitive to green light.")
AnnotationAssertion(rdfs:label obo:CL_0000496 "green sensitive photoreceptor cell")
SubClassOf(obo:CL_0000496 obo:CL_0000490)

# Class: obo:CL_0000497 (red sensitive photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000497 "A photoreceptor cell that is sensitive to red light.")
AnnotationAssertion(rdfs:label obo:CL_0000497 "red sensitive photoreceptor cell")
SubClassOf(obo:CL_0000497 obo:CL_0000490)

# Class: obo:CL_0000498 (inhibitory interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Interneuron") obo:IAO_0000115 obo:CL_0000498 "An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000498 "FMA:84776")
AnnotationAssertion(rdfs:label obo:CL_0000498 "inhibitory interneuron")
SubClassOf(obo:CL_0000498 obo:CL_0000099)

# Class: obo:CL_0000499 (stromal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D017154") obo:IAO_0000115 obo:CL_0000499 "A connective tissue cell of an organ found in the loose connective tissue.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000499 "BTO:0002064")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000499 "FMA:83624")
AnnotationAssertion(rdfs:label obo:CL_0000499 "stromal cell")
SubClassOf(obo:CL_0000499 obo:CL_0002320)
SubClassOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000500 (follicular epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000500 "An epithelial somatic cell associated with a maturing oocyte.")
AnnotationAssertion(rdfs:label obo:CL_0000500 "follicular epithelial cell")
SubClassOf(obo:CL_0000500 obo:CL_0000066)

# Class: obo:CL_0000501 (granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D006107") obo:IAO_0000115 obo:CL_0000501 "A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000501 "BTO:0000542")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000501 "CALOHA:TS-0729")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000501 "FMA:18718")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000501 "granulosa cell of ovary")
AnnotationAssertion(rdfs:label obo:CL_0000501 "granulosa cell")
SubClassOf(obo:CL_0000501 obo:CL_0000174)
SubClassOf(obo:CL_0000501 obo:CL_0002174)
SubClassOf(obo:CL_0000501 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4033066))

# Class: obo:CL_0000502 (type D enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D019864") obo:IAO_0000115 obo:CL_0000502 "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000502 "FMA:62935")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000502 "D cell")
AnnotationAssertion(rdfs:label obo:CL_0000502 "type D enteroendocrine cell")
SubClassOf(obo:CL_0000502 obo:CL_0000164)
SubClassOf(obo:CL_0000502 obo:CL_0000165)
SubClassOf(obo:CL_0000502 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070253))

# Class: obo:CL_0000503 (theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013799") Annotation(oboInOwl:hasDbXref "PMID:15833266") Annotation(oboInOwl:hasDbXref "PMID:36758341") obo:IAO_0000115 obo:CL_0000503 "A specialized stromal cell that forms the theca layer outside the basal lamina lining the ovarian follicle, appearing during the secondary follicle stage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000503 "BTO:0002850")
AnnotationAssertion(rdfs:label obo:CL_0000503 "theca cell")
SubClassOf(obo:CL_0000503 obo:CL_0000499)
SubClassOf(obo:CL_0000503 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000155))

# Class: obo:CL_0000504 (enterochromaffin-like cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D019861") obo:IAO_0000115 obo:CL_0000504 "A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000504 "BTO:0002692")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000504 "ECL")
AnnotationAssertion(rdfs:comment obo:CL_0000504 "Consider enterochromaffin cell (CL:0002065). For several years this cell type was \"enterochromaffin cell\" despite a MESH dbxref and a free text definition that clearly meant enterochromaffin-like cell.")
AnnotationAssertion(rdfs:label obo:CL_0000504 "enterochromaffin-like cell")
SubClassOf(obo:CL_0000504 obo:CL_0000164)
SubClassOf(obo:CL_0000504 obo:CL_0002274)

# Class: obo:CL_0000505 (substance P secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000505 "A peptide hormone secreting cell that secretes substance P.")
AnnotationAssertion(rdfs:label obo:CL_0000505 "substance P secreting cell")
SubClassOf(obo:CL_0000505 obo:CL_0000167)

# Class: obo:CL_0000506 (enkephalin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000506 "An endorphine cell that secretes enkephalin.")
AnnotationAssertion(rdfs:label obo:CL_0000506 "enkephalin secreting cell")
SubClassOf(obo:CL_0000506 obo:CL_0000507)

# Class: obo:CL_0000507 (endorphin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000507 "A peptide hormone secreting cell that secretes endorphin.")
AnnotationAssertion(rdfs:label obo:CL_0000507 "endorphin secreting cell")
SubClassOf(obo:CL_0000507 obo:CL_0000167)

# Class: obo:CL_0000508 (type G enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "MESH:D019863") Annotation(oboInOwl:hasDbXref "PMID:10700044") Annotation(oboInOwl:hasDbXref "PMID:35674015") Annotation(oboInOwl:hasDbXref "PMID:37240181") obo:IAO_0000115 obo:CL_0000508 "An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000508 "BTO:0004108")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000508 "FMA:67609")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000508 "G cell")
AnnotationAssertion(rdfs:label obo:CL_0000508 "type G enteroendocrine cell")
SubClassOf(obo:CL_0000508 obo:CL_0000164)
SubClassOf(obo:CL_0000508 obo:CL_0000165)
SubClassOf(obo:CL_0000508 obo:CL_0000506)
SubClassOf(obo:CL_0000508 obo:CL_0000509)

# Class: obo:CL_0000509 (gastrin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000509 "A peptide hormone secreting cell that secretes gastrin.")
AnnotationAssertion(rdfs:label obo:CL_0000509 "gastrin secreting cell")
SubClassOf(obo:CL_0000509 obo:CL_0000167)

# Class: obo:CL_0000510 (paneth cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "MESH:D019879") Annotation(oboInOwl:hasDbXref "PMID:29184701") Annotation(oboInOwl:hasDbXref "PMID:32308658") Annotation(oboInOwl:hasDbXref "PMID:33484640") obo:IAO_0000115 obo:CL_0000510 "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "BTO:0000993")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "FMA:62897")
AnnotationAssertion(rdfs:label obo:CL_0000510 "paneth cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000510 obo:CL_0000066)
SubClassOf(obo:CL_0000510 obo:CL_0000323)
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011184))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005773))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4047017))

# Class: obo:CL_0000511 (androgen binding protein secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") obo:IAO_0000115 obo:CL_0000511 "A peptide hormone secreting cell that secretes androgen binding protein.")
AnnotationAssertion(rdfs:label obo:CL_0000511 "androgen binding protein secreting cell")
SubClassOf(obo:CL_0000511 obo:CL_0000154)

# Class: obo:CL_0000512 (obsolete paracrine cell)

AnnotationAssertion(oboInOwl:consider obo:CL_0000512 obo:CL_0000151)
AnnotationAssertion(rdfs:comment obo:CL_0000512 "The term paracrine describes a role of a secreted hormone. There are a vast number of cell types that could fit this description, however it is difficult to know every case where a secreted hormone has paracrine effects.")
AnnotationAssertion(rdfs:label obo:CL_0000512 "obsolete paracrine cell")
AnnotationAssertion(owl:deprecated obo:CL_0000512 "true"^^xsd:boolean)

# Class: obo:CL_0000513 (cardiac muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D032386") obo:IAO_0000115 obo:CL_0000513 "A precursor cell destined to differentiate into cardiac muscle cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000513 "FMA:84797")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000513 "cardiac muscle progenitor cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000513 "cardiomyocyte progenitor cell")
AnnotationAssertion(rdfs:label obo:CL_0000513 "cardiac muscle myoblast")
EquivalentClasses(obo:CL_0000513 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001133) ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000746)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000513 obo:CL_0000056)

# Class: obo:CL_0000514 (smooth muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D032390") obo:IAO_0000115 obo:CL_0000514 "A precursor cell destined to differentiate into smooth muscle myocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000514 "FMA:84798")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D032390") oboInOwl:hasExactSynonym obo:CL_0000514 "myoblast, smooth muscle")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000514 "satellite cell")
AnnotationAssertion(rdfs:label obo:CL_0000514 "smooth muscle myoblast")
EquivalentClasses(obo:CL_0000514 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000192)))

# Class: obo:CL_0000515 (skeletal muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000515 "A myoblast that differentiates into skeletal muscle fibers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000515 "FMA:84799")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000515 "skeletal myoblast")
AnnotationAssertion(rdfs:label obo:CL_0000515 "skeletal muscle myoblast")
EquivalentClasses(obo:CL_0000515 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008002)))
SubClassOf(obo:CL_0000515 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000355))

# Class: obo:CL_0000516 (perineuronal satellite cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D027161") obo:IAO_0000115 obo:CL_0000516 "A non-neuronal cell that surrounds the neuronal cell bodies of the ganglia.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000516 "FMA:54550")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000516 "perineural satellite cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000516 "perineuronal satellite oligodendroglial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000516 "satellite oligodendrocyte")
AnnotationAssertion(rdfs:label obo:CL_0000516 "perineuronal satellite cell")
SubClassOf(obo:CL_0000516 obo:CL_0000123)
SubClassOf(obo:CL_0000516 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000339))

# Class: obo:CL_0000517 (macrophage derived foam cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:20213546") obo:IAO_0000115 obo:CL_0000517 "A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000517 "lipophage")
AnnotationAssertion(rdfs:label obo:CL_0000517 "macrophage derived foam cell")
SubClassOf(obo:CL_0000517 obo:CL_0000891)
SubClassOf(obo:CL_0000517 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000235))

# Class: obo:CL_0000518 (phagocyte (sensu Vertebrata))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000518 "A phagocyte in vertebrates that is able to phagocytosis.")
AnnotationAssertion(rdfs:label obo:CL_0000518 "phagocyte (sensu Vertebrata)")
SubClassOf(obo:CL_0000518 obo:CL_0000234)
SubClassOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000519 (phagocyte (sensu Nematoda and Protostomia))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000519 "A phagocyte from organisms in the Nematoda or Protostomia clades.")
AnnotationAssertion(obo:RO_0002161 obo:CL_0000519 obo:NCBITaxon_33511)
AnnotationAssertion(rdfs:label obo:CL_0000519 "phagocyte (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0000519 obo:CL_0000234)

# Class: obo:CL_0000520 (prokaryotic cell)

AnnotationAssertion(obo:RO_0002161 obo:CL_0000520 obo:NCBITaxon_2759)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000520 "MESH:D011387")
AnnotationAssertion(rdfs:label obo:CL_0000520 "prokaryotic cell")
SubClassOf(obo:CL_0000520 obo:CL_0000000)

# Class: obo:CL_0000521 (fungal cell)

AnnotationAssertion(rdfs:label obo:CL_0000521 "fungal cell")
EquivalentClasses(obo:CL_0000521 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_4751)))
SubClassOf(obo:CL_0000521 obo:CL_0000255)

# Class: obo:CL_0000522 (obsolete spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000522 "OBSOLETE: The reproductive structure of bacteria, fungi and cryptograms.")
AnnotationAssertion(rdfs:label obo:CL_0000522 "obsolete spore")
AnnotationAssertion(owl:deprecated obo:CL_0000522 "true"^^xsd:boolean)

# Class: obo:CL_0000523 (mononuclear cytotrophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0000523 "A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000523 "FMA:83042")
AnnotationAssertion(rdfs:label obo:CL_0000523 "mononuclear cytotrophoblast cell")
SubClassOf(obo:CL_0000523 obo:CL_0000351)

# Class: obo:CL_0000524 (spheroplast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D013104") obo:IAO_0000115 obo:CL_0000524 "A cell, usually of bacteria or yeast, which has partially lost its cell wall.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000524 "sphaeroplast")
AnnotationAssertion(rdfs:label obo:CL_0000524 "spheroplast")
SubClassOf(obo:CL_0000524 obo:CL_0000371)

# Class: obo:CL_0000525 (syncytiotrophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0000525 "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000525 "FMA:83043")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11787150") oboInOwl:hasExactSynonym obo:CL_0000525 "syncytial trophoblast cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21733368") oboInOwl:hasExactSynonym obo:CL_0000525 "syncytiotrophoblastic cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000525 "plasmidotrophoblast cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000525 "syntrophoblast cell")
AnnotationAssertion(rdfs:label obo:CL_0000525 "syncytiotrophoblast cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0000525 "https://github.com/obophenotype/cell-ontology/issues/2100")
EquivalentClasses(obo:CL_0000525 ObjectIntersectionOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908)))
SubClassOf(obo:CL_0000525 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000371))
SubClassOf(obo:CL_0000525 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0000768))

# Class: obo:CL_0000526 (afferent neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D009475") obo:IAO_0000115 obo:CL_0000526 "A neuron which conveys sensory information centrally from the periphery.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000526 "FMA:87653")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000526 "input neuron")
AnnotationAssertion(rdfs:label obo:CL_0000526 "afferent neuron")
SubClassOf(obo:CL_0000526 obo:CL_0000540)

# Class: obo:CL_0000527 (efferent neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009476") obo:IAO_0000115 obo:CL_0000527 "A neuron which sends impulses peripherally to activate muscles or secretory cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000527 "output neuron")
AnnotationAssertion(rdfs:label obo:CL_0000527 "efferent neuron")
SubClassOf(obo:CL_0000527 obo:CL_0000540)

# Class: obo:CL_0000528 (nitrergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D026602") obo:IAO_0000115 obo:CL_0000528 "A nerve cell where transmission is mediated by nitric oxide.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000528 "FMA:84792")
AnnotationAssertion(rdfs:label obo:CL_0000528 "nitrergic neuron")
SubClassOf(obo:CL_0000528 obo:CL_0000540)

# Class: obo:CL_0000529 (pigmented epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_0000529 "pigmented epithelial cell")
SubClassOf(obo:CL_0000529 obo:CL_0000710)

# Class: obo:CL_0000530 (primary neuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") Annotation(oboInOwl:hasDbXref "doi:10.1242/dev.108.1.121") obo:IAO_0000115 obo:CL_0000530 "A neuron that develops during the early segmentation stages in teleosts, before the neural tube is formed.")
AnnotationAssertion(rdfs:label obo:CL_0000530 "primary neuron (sensu Teleostei)")
SubClassOf(obo:CL_0000530 obo:CL_0000540)
SubClassOf(obo:CL_0000530 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002240))
SubClassOf(Annotation(obo:IAO_0000233 "https://github.com/obophenotype/cell-ontology/pull/1950") obo:CL_0000530 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_32443))

# Class: obo:CL_0000531 (primary sensory neuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") obo:IAO_0000115 obo:CL_0000531 "A primary neuron (sensu Teleostei) that has a sensory function.")
AnnotationAssertion(rdfs:label obo:CL_0000531 "primary sensory neuron (sensu Teleostei)")
EquivalentClasses(obo:CL_0000531 ObjectIntersectionOf(obo:CL_0000101 obo:CL_0000530))

# Class: obo:CL_0000532 (CAP motoneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17971221") Annotation(oboInOwl:hasDbXref "PMID:35431796") obo:IAO_0000115 obo:CL_0000532 "A primary motor neuron with its soma in the caudal region of a spinal cord. The axon of this motoneuron exit the spinal cord from one single point and innervates the lateral surface of ventral axial muscles")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3746410") oboInOwl:hasExactSynonym obo:CL_0000532 "CaP motorneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17971221") oboInOwl:hasRelatedSynonym obo:CL_0000532 "cap cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18077593") oboInOwl:hasRelatedSynonym obo:CL_0000532 "caudal primary motor neuron")
AnnotationAssertion(rdfs:label obo:CL_0000532 "CAP motoneuron")
SubClassOf(obo:CL_0000532 obo:CL_0000533)

# Class: obo:CL_0000533 (primary motor neuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") obo:IAO_0000115 obo:CL_0000533 "A primary neuron (sensu Teleostei) that has a motor function.")
AnnotationAssertion(rdfs:label obo:CL_0000533 "primary motor neuron (sensu Teleostei)")
SubClassOf(obo:CL_0000533 obo:CL_0000100)
SubClassOf(obo:CL_0000533 obo:CL_0000530)

# Class: obo:CL_0000534 (primary interneuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") obo:IAO_0000115 obo:CL_0000534 "A primary neuron (sensu Teleostei) that is neither a sensory neuron or a motor neuron.")
AnnotationAssertion(rdfs:label obo:CL_0000534 "primary interneuron (sensu Teleostei)")
SubClassOf(obo:CL_0000534 obo:CL_0000099)
SubClassOf(obo:CL_0000534 obo:CL_0000530)

# Class: obo:CL_0000535 (secondary neuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") Annotation(oboInOwl:hasDbXref "doi:10.1242/dev.108.1.121") obo:IAO_0000115 obo:CL_0000535 "A neuron of teleosts that develops later than a primary neuron, typically during the larval stages.")
AnnotationAssertion(rdfs:label obo:CL_0000535 "secondary neuron (sensu Teleostei)")
SubClassOf(obo:CL_0000535 obo:CL_0000540)
SubClassOf(obo:CL_0000535 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002240))
SubClassOf(Annotation(obo:IAO_0000233 "https://github.com/obophenotype/cell-ontology/pull/1950") obo:CL_0000535 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_32443))
SubClassOf(obo:CL_0000535 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0002342))

# Class: obo:CL_0000536 (secondary motor neuron (sensu Teleostei))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1842357") obo:IAO_0000115 obo:CL_0000536 "A secondary neuron (sensu Teleostei) that has a motor function.")
AnnotationAssertion(rdfs:label obo:CL_0000536 "secondary motor neuron (sensu Teleostei)")
EquivalentClasses(obo:CL_0000536 ObjectIntersectionOf(obo:CL_0000100 obo:CL_0000535))

# Class: obo:CL_0000537 (obsolete antipodal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:047125208") obo:IAO_0000115 obo:CL_0000537 "Obsolete. Use PO:0020093 from Plant Ontology instead. OBSOLETE, use term from plant ontology. A cell located at the chalazal end of the mature embryo sac in angiosperms.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000537 obo:PO_0020093)
AnnotationAssertion(rdfs:label obo:CL_0000537 "obsolete antipodal cell")
AnnotationAssertion(owl:deprecated obo:CL_0000537 "true"^^xsd:boolean)

# Class: obo:CL_0000538 (obsolete epidermal initial)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:lr") obo:IAO_0000115 obo:CL_0000538 "Obsolete. Use PO:0000349 from Plant Ontology instead. A relatively unspecialized cell that will give rise to specialized cell types of the epidermis.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000538 obo:PO_0000349)
AnnotationAssertion(rdfs:label obo:CL_0000538 "obsolete epidermal initial")
AnnotationAssertion(owl:deprecated obo:CL_0000538 "true"^^xsd:boolean)

# Class: obo:CL_0000539 (obsolete idioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000539 "OBSOLETE: A cell in a tissue that markedly differs in form, size, or contents from other cells in the same tissue.")
AnnotationAssertion(rdfs:label obo:CL_0000539 "obsolete idioblast")
AnnotationAssertion(owl:deprecated obo:CL_0000539 "true"^^xsd:boolean)

# Class: obo:CL_0000540 (neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D009474") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Neuron") obo:IAO_0000115 obo:CL_0000540 "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000540 "BTO:0000938")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000540 "CALOHA:TS-0683")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000540 "FMA:54527")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000540 "VHOG:0001483")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000540 "WBbt:0003679")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000540 "nerve cell")
AnnotationAssertion(rdfs:comment obo:CL_0000540 "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.")
AnnotationAssertion(rdfs:label obo:CL_0000540 "neuron")
AnnotationAssertion(foaf:depiction obo:CL_0000540 "https://www.swissbiopics.org/api/image/Neuron_cells.svg"^^xsd:anyURI)
SubClassOf(obo:CL_0000540 obo:CL_0000393)
SubClassOf(obo:CL_0000540 obo:CL_0000404)
SubClassOf(obo:CL_0000540 obo:CL_0002319)
SubClassOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019226))

# Class: obo:CL_0000541 (melanoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000541 "A cell that originates from the neural crest and differentiates into a pigment cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000541 "BTO:0003217")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000541 "FMA:83377")
AnnotationAssertion(rdfs:comment obo:CL_0000541 "Derived from UBERON:0002342 neural crest.")
AnnotationAssertion(rdfs:label obo:CL_0000541 "melanoblast")
SubClassOf(obo:CL_0000541 obo:CL_0011026)
SubClassOf(obo:CL_0000541 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0000542 (lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0683073696") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000542 "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "BTO:0000775")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "CALOHA:TS-0583")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "FMA:62863")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "MESH:D008214")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "VHOG:0001535")
AnnotationAssertion(rdfs:comment obo:CL_0000542 "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)")
AnnotationAssertion(rdfs:label obo:CL_0000542 "lymphocyte")
EquivalentClasses(obo:CL_0000542 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017500) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000542 obo:CL_0000738)
SubClassOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051))
DisjointClasses(obo:CL_0000542 obo:CL_0000766)

# Class: obo:CL_0000543 (obsolete sieve tube member)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000543 "Obsolete. Use PO:0000289 from Plant Ontology instead. One of the series of cellular components of a sieve tube. It shows a more or less pronounced differentiation between sieve plates (wide pores) and lateral sieve areas (narrow pores). Also sieve tube element and the obsolete sieve tube segment.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000543 obo:PO_0000289)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000543 "sieve tube element")
AnnotationAssertion(rdfs:label obo:CL_0000543 "obsolete sieve tube member")
AnnotationAssertion(owl:deprecated obo:CL_0000543 "true"^^xsd:boolean)

# Class: obo:CL_0000544 (slowly adapting mechanoreceptor cell)

AnnotationAssertion(rdfs:label obo:CL_0000544 "slowly adapting mechanoreceptor cell")
SubClassOf(obo:CL_0000544 obo:CL_0000199)

# Class: obo:CL_0000545 (T-helper 1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19375293") Annotation(oboInOwl:hasDbXref "PMID:20303875") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000545 "A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000545 "BTO:0001678")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000545 "FMA:84382")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9419219") oboInOwl:hasExactSynonym obo:CL_0000545 "T helper cells type 1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "T(H)-1 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "Th1 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "helper T cell type 1")
AnnotationAssertion(rdfs:comment obo:CL_0000545 "This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000545 "T-helper 1 cell")
EquivalentClasses(obo:CL_0000545 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001835) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000545 obo:CL_0000492)
SubClassOf(obo:CL_0000545 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0000546 (T-helper 2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19375293") Annotation(oboInOwl:hasDbXref "PMID:20103781") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000546 "A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000546 "BTO:0001679")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000546 "FMA:84385")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000546 "MESH:D018418")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9419219") oboInOwl:hasExactSynonym obo:CL_0000546 "T helper cells type 2")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "T(H)-2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "Th2 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "Th2 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "Th2 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "Th2 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "Th2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "helper T cell type 2")
AnnotationAssertion(rdfs:comment obo:CL_0000546 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell.")
AnnotationAssertion(rdfs:label obo:CL_0000546 "T-helper 2 cell")
EquivalentClasses(obo:CL_0000546 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001941) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000546 obo:CL_0000492)
SubClassOf(obo:CL_0000546 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0000547 (proerythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:1638021") obo:IAO_0000115 obo:CL_0000547 "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000547 "FMA:83518")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000547 "rubriblast")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000547 "pronormoblast")
AnnotationAssertion(rdfs:label obo:CL_0000547 "proerythroblast")
EquivalentClasses(obo:CL_0000547 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000547 obo:CL_0000764)
SubClassOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000038))

# Class: obo:CL_0000548 (obsolete animal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000548 "OBSOLETE. A native cell that is part of some Metazoa.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000548 <https://github.com/obophenotype/cell-ontology/issues/2124>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000548 obo:CL_0000000)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000548 "metazoan cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000548 ubprop:_upper_level)
AnnotationAssertion(rdfs:label obo:CL_0000548 "obsolete animal cell")
AnnotationAssertion(owl:deprecated obo:CL_0000548 "true"^^xsd:boolean)
AnnotationAssertion(foaf:depiction obo:CL_0000548 "https://www.swissbiopics.org/api/image/Animal_cells.svg"^^xsd:anyURI)

# Class: obo:CL_0000549 (basophilic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000549 "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000549 "FMA:83505")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000549 "basophilic normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000549 "early erythroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000549 "early normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000549 "prorubricyte")
AnnotationAssertion(rdfs:label obo:CL_0000549 "basophilic erythroblast")
EquivalentClasses(obo:CL_0000549 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000549 obo:CL_0000765)
SubClassOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547))

# Class: obo:CL_0000550 (polychromatophilic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000550 "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000550 "FMA:83506")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "intermediate erythroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "intermediate normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "polychromatic erythroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "polychromatic normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "polychromatophilic normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "rubricyte")
AnnotationAssertion(rdfs:label obo:CL_0000550 "polychromatophilic erythroblast")
EquivalentClasses(obo:CL_0000550 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017504) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000550 obo:CL_0000765)
SubClassOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000549))

# Class: obo:CL_0000551 (unimodal nocireceptor)

AnnotationAssertion(rdfs:label obo:CL_0000551 "unimodal nocireceptor")
SubClassOf(obo:CL_0000551 obo:CL_0000198)

# Class: obo:CL_0000552 (orthochromatic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000552 "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000552 "FMA:84646")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000552 "acidophilic erythroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000552 "eosinophilic erythroblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000552 "late erythoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000552 "orthochromatic normoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000552 "pyknotic eto enrythroblast")
AnnotationAssertion(rdfs:label obo:CL_0000552 "orthochromatic erythroblast")
EquivalentClasses(obo:CL_0000552 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0030263)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000552 obo:CL_0000765)
SubClassOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000550))

# Class: obo:CL_0000553 (megakaryocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000553 "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000553 "BTO:0001164")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000553 "CALOHA:TS-0610")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000553 "FMA:84235")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000553 "MESH:D055016")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11722431") Annotation(oboInOwl:hasDbXref "PMID:12482498") oboInOwl:hasExactSynonym obo:CL_0000553 "CFU-Meg")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMCID:PMC1794060") oboInOwl:hasExactSynonym obo:CL_0000553 "Meg-CFC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21116988") oboInOwl:hasExactSynonym obo:CL_0000553 "MkP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000553 "colony-forming unit-megakaryocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000553 "megacaryoblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000553 "megacaryocyte progenitor cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000553 "megakaryoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12482498") oboInOwl:hasExactSynonym obo:CL_0000553 "megakaryocytic progenitor cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000553 "promegacaryocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000553 "promegakaryocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000553 "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000553 "megakaryocyte progenitor cell")
EquivalentClasses(obo:CL_0000553 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007113) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030219)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000553 obo:CL_0000839)
SubClassOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050))

# Class: obo:CL_0000554 (gastrin stimulating hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000554 "A peptide hormone secreting cell that secretes gastrin stimulating hormone.")
AnnotationAssertion(rdfs:label obo:CL_0000554 "gastrin stimulating hormone secreting cell")
SubClassOf(obo:CL_0000554 obo:CL_0000167)

# Class: obo:CL_0000555 (obsolete neuronal brush cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000555 obo:CL_4023161)
AnnotationAssertion(rdfs:label obo:CL_0000555 "obsolete neuronal brush cell")
AnnotationAssertion(owl:deprecated obo:CL_0000555 "true"^^xsd:boolean)

# Class: obo:CL_0000556 (megakaryocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "MESH:D008533") Annotation(oboInOwl:hasDbXref "PMID:31043076") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Megakaryocyte") obo:IAO_0000115 obo:CL_0000556 "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000556 "BTO:0000843")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000556 "CALOHA:TS-0611")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000556 "FMA:83555")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000556 "megacaryocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000556 "megalocaryocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000556 "megalokaryocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000556 "Megakaryocytes are reportedly CD181-positive and CD182-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000556 "megakaryocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000556 obo:CL_0000763)
SubClassOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001393))
SubClassOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000553))
DisjointClasses(obo:CL_0000556 obo:CL_0000764)

# Class: obo:CL_0000557 (granulocyte monocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "MESH:D055014") Annotation(oboInOwl:hasDbXref "PMCID:PMC2213186") Annotation(oboInOwl:hasDbXref "PMCID:PMC548021") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:16647566") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/CFU-GM") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0000557 "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") oboInOwl:hasBroadSynonym obo:CL_0000557 "CFU-C , Colony forming unit in culture")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMCID:PMC2213186") Annotation(oboInOwl:hasDbXref "PMCID:PMC548021") oboInOwl:hasExactSynonym obo:CL_0000557 "colony forming unit granulocyte macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMCID:PMC2213186") Annotation(oboInOwl:hasDbXref "PMCID:PMC548021") oboInOwl:hasExactSynonym obo:CL_0000557 "granulocyte-macrophage progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000557 "granulocyte/monocyte precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000557 "granulocyte/monocyte progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMCID:PMC2213186") Annotation(oboInOwl:hasDbXref "PMCID:PMC548021") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000557 "CFU-GM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMCID:PMC2213186") Annotation(oboInOwl:hasDbXref "PMCID:PMC548021") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000557 "GMP")
AnnotationAssertion(rdfs:comment obo:CL_0000557 "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000557 "granulocyte monocyte progenitor cell")
EquivalentClasses(obo:CL_0000557 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000007857) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000007858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030851)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000557 obo:CL_0002032)
SubClassOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049))

# Class: obo:CL_0000558 (reticulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15946868") Annotation(oboInOwl:hasDbXref "PMID:2037622") obo:IAO_0000115 obo:CL_0000558 "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000558 "BTO:0001173")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000558 "CALOHA:TS-0864")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000558 "MESH:D012156")
AnnotationAssertion(rdfs:label obo:CL_0000558 "reticulocyte")
EquivalentClasses(obo:CL_0000558 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0071971)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000558 obo:CL_0000764)
SubClassOf(obo:CL_0000558 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000552))

# Class: obo:CL_0000559 (promonocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000559 "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000559 "BTO:0004657")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000559 "FMA:83551")
AnnotationAssertion(rdfs:comment obo:CL_0000559 "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000559 "promonocyte")
EquivalentClasses(obo:CL_0000559 ObjectIntersectionOf(obo:CL_0002194 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000559 obo:CL_0002194)
SubClassOf(obo:CL_0000559 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000040))

# Class: obo:CL_0000560 (band form neutrophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:10618520") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000560 "A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000560 "band")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000560 "band cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000560 "band form")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000560 "stab cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000560 "rod neutrophil")
AnnotationAssertion(rdfs:comment obo:CL_0000560 "Found in the Band 1 fraction.")
AnnotationAssertion(rdfs:label obo:CL_0000560 "band form neutrophil")
EquivalentClasses(obo:CL_0000560 ObjectIntersectionOf(obo:CL_0000096 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007597) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010799) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009129) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000010543) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001337) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001580)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000560 obo:CL_0000096)
SubClassOf(obo:CL_0000560 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000582))

# Class: obo:CL_0000561 (amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D025042") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Amacrine_cell&oldid=1023572246") obo:IAO_0000115 obo:CL_0000561 "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000561 "BTO:0004044")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000561 "FMA:67766")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000561 "amacrine neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000561 "AC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000561 "ACs")
AnnotationAssertion(rdfs:label obo:CL_0000561 "amacrine cell")
SubClassOf(obo:CL_0000561 obo:CL_0000099)
SubClassOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966))
SubClassOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0000740))
SubClassOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0000562 (nucleate erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOc:tfm") obo:IAO_0000115 obo:CL_0000562 "An erythrocyte having a nucleus.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000562 "RBC")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000562 "red blood cell")
AnnotationAssertion(rdfs:label obo:CL_0000562 "nucleate erythrocyte")
EquivalentClasses(obo:CL_0000562 ObjectIntersectionOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000562 obo:CL_0000232)
SubClassOf(obo:CL_0000562 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002421))

# Class: obo:CL_0000563 (endospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000563 "A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000563 "BTO:0002779")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000563 "bacterial spore")
AnnotationAssertion(rdfs:label obo:CL_0000563 "endospore")
SubClassOf(obo:CL_0000563 obo:CL_0000520)

# Class: obo:CL_0000564 (neutrophilic promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") obo:IAO_0000115 obo:CL_0000564 "A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000564 "FMA:84196")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000564 "neutrophilic premyelocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000564 "neutrophilic progranulocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000564 "These cells are CD11b-negative, CD15-positive, CD16-negative, CD49d-positive, CD68-positive, CD35-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.")
AnnotationAssertion(rdfs:label obo:CL_0000564 "neutrophilic promyelocyte")
EquivalentClasses(obo:CL_0000564 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014362) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000564 obo:CL_0000836)
SubClassOf(obo:CL_0000564 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000042))

# Class: obo:CL_0000565 (fat body cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000565 "A cell found in fat bodies whose primary function is intermediary metabolism.")
AnnotationAssertion(rdfs:label obo:CL_0000565 "fat body cell")
SubClassOf(obo:CL_0000565 obo:CL_0000325)

# Class: obo:CL_0000566 (angioblastic mesenchymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12768659") obo:IAO_0000115 obo:CL_0000566 "A mesenchymal stem cell capable of developing into blood vessel endothelium.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000566 "angioblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000566 "chondroplast")
AnnotationAssertion(rdfs:comment obo:CL_0000566 "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000566 "angioblastic mesenchymal cell")
EquivalentClasses(obo:CL_0000566 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001444) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002112) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016043)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000566 obo:CL_0000134)
SubClassOf(obo:CL_0000566 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000567 (polymodal nocireceptor)

AnnotationAssertion(rdfs:label obo:CL_0000567 "polymodal nocireceptor")
SubClassOf(obo:CL_0000567 obo:CL_0000198)

# Class: obo:CL_0000568 (amine precursor uptake and decarboxylation cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000568 "A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000568 "BTO:0003866")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000568 "FMA:83114")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000568 "MESH:D001078")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000568 "APUD cell")
AnnotationAssertion(rdfs:label obo:CL_0000568 "amine precursor uptake and decarboxylation cell")
SubClassOf(obo:CL_0000568 obo:CL_0000165)

# Class: obo:CL_0000569 (cardiac mesenchymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18816864") obo:IAO_0000115 obo:CL_0000569 "A mesenchymal cell found in the developing heart and that develops into some part of the heart.  These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.")
AnnotationAssertion(rdfs:label obo:CL_0000569 "cardiac mesenchymal cell")
EquivalentClasses(obo:CL_0000569 ObjectIntersectionOf(obo:CL_0008019 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0002494)))
SubClassOf(obo:CL_0000569 obo:CL_2000073)

# Class: obo:CL_0000570 (parafollicular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0000570 "A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. This cell expresses a form of the neural cell adhesion molecule (N-CAM) on its surface and secretes calcitonin and serotonin (5-hydroxytryptamine).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000570 "FMA:68653")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000570 "SCTID:176770005")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000570 "C cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExactSynonym obo:CL_0000570 "C cell of thyroid gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExactSynonym obo:CL_0000570 "clear cell of thyroid gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExactSynonym obo:CL_0000570 "parafollicular cell of thyroid gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExactSynonym obo:CL_0000570 "thyroid parafollicular cell")
AnnotationAssertion(rdfs:label obo:CL_0000570 "parafollicular cell")
EquivalentClasses(obo:CL_0000570 ObjectIntersectionOf(obo:CL_0000710 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001024) ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0001820 ObjectSomeValuesFrom(obo:RO_0002339 obo:UBERON_0001009))) ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0036161 ObjectSomeValuesFrom(obo:RO_0002339 obo:UBERON_0001009)))))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000570 obo:CL_0000710)
SubClassOf(obo:CL_0000570 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001747))
SubClassOf(obo:CL_0000570 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0000571 (leucophore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000571 "A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light.")
AnnotationAssertion(rdfs:label obo:CL_0000571 "leucophore")
SubClassOf(obo:CL_0000571 obo:CL_0000147)
SubClassOf(obo:CL_0000571 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005003))

# Class: obo:CL_0000572 (obo:CL_0000572)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000572 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000572 obo:CL_0000148)
AnnotationAssertion(owl:deprecated obo:CL_0000572 "true"^^xsd:boolean)

# Class: obo:CL_0000573 (retinal cone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D017949") obo:IAO_0000115 obo:CL_0000573 "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000573 "BTO:0001036")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000573 "CALOHA:TS-0866")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000573 "FMA:67748")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") oboInOwl:hasRelatedSynonym obo:CL_0000573 "cone")
AnnotationAssertion(rdfs:label obo:CL_0000573 "retinal cone cell")
SubClassOf(obo:CL_0000573 obo:CL_0010009)
SubClassOf(obo:CL_0000573 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002672))

# Class: obo:CL_0000574 (erythrophore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000574 "A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance.")
AnnotationAssertion(rdfs:label obo:CL_0000574 "erythrophore")
SubClassOf(obo:CL_0000574 obo:CL_0000147)
SubClassOf(obo:CL_0000574 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005004))

# Class: obo:CL_0000575 (corneal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000575 "An epithelial cell of the cornea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000575 "BTO:0004298")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000575 "CALOHA:TS-0173")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000575 "FMA:70551")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70551") oboInOwl:hasExactSynonym obo:CL_0000575 "epithelial cell of cornea")
AnnotationAssertion(rdfs:label obo:CL_0000575 "corneal epithelial cell")
EquivalentClasses(obo:CL_0000575 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001772)))
SubClassOf(obo:CL_0000575 obo:CL_0002159)

# Class: obo:CL_0000576 (monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "MESH:D009000") obo:IAO_0000115 obo:CL_0000576 "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000576 "BTO:0000876")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000576 "CALOHA:TS-0638")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000576 "FMA:62864")
AnnotationAssertion(rdfs:comment obo:CL_0000576 "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000576 "monocyte")
EquivalentClasses(obo:CL_0000576 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030316) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011)))
SubClassOf(obo:CL_0000576 obo:CL_0000113)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000576 obo:CL_0000766)
SubClassOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000559))

# Class: obo:CL_0000577 (type EC enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9505449") obo:IAO_0000115 obo:CL_0000577 "A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000577 "FMA:62934")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000577 "FMA:83132")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000577 "MESH:D004759")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000577 "Kulchitsky cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000577 "argentaffin cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000577 "enterochromaffin cell")
AnnotationAssertion(rdfs:label obo:CL_0000577 "type EC enteroendocrine cell")
SubClassOf(obo:CL_0000577 obo:CL_0000164)
SubClassOf(obo:CL_0000577 obo:CL_0000165)
SubClassOf(obo:CL_0000577 obo:CL_0000166)
SubClassOf(obo:CL_0000577 obo:CL_0000458)
SubClassOf(obo:CL_0000577 obo:CL_0000506)
SubClassOf(obo:CL_0000577 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004786))

# Class: obo:CL_0000578 (experimentally modified cell in vitro)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0000578 "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.")
AnnotationAssertion(rdfs:comment obo:CL_0000578 "This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12")
AnnotationAssertion(rdfs:label obo:CL_0000578 "experimentally modified cell in vitro")
SubClassOf(obo:CL_0000578 obo:CL_0001034)

# Class: obo:CL_0000579 (border follicle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00004905") obo:IAO_0000115 obo:CL_0000579 "A follicle cell that migrates from the anterior pole of the insect egg chamber to the anterior of the oocyte where they participate in the formation of the micropyle.")
AnnotationAssertion(rdfs:label obo:CL_0000579 "border follicle cell")
SubClassOf(obo:CL_0000579 obo:CL_0000477)

# Class: obo:CL_0000580 (neutrophilic myelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:10618520") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000580 "A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000580 "BTO:0003455")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000580 "FMA:83540")
AnnotationAssertion(rdfs:comment obo:CL_0000580 "These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction.")
AnnotationAssertion(rdfs:label obo:CL_0000580 "neutrophilic myelocyte")
EquivalentClasses(obo:CL_0000580 ObjectIntersectionOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005310) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009725) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009978) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000580 obo:CL_0000776)
SubClassOf(obo:CL_0000580 obo:CL_0002193)
SubClassOf(obo:CL_0000580 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000564))

# Class: obo:CL_0000581 (peritoneal macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D017737") Annotation(oboInOwl:hasDbXref "PMID:15771589") Annotation(oboInOwl:hasDbXref "PMID:19201820") obo:IAO_0000115 obo:CL_0000581 "A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000581 "BTO:0001034")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000581 "FMA:83025")
AnnotationAssertion(rdfs:comment obo:CL_0000581 "Markers: Mouse: F4/80-high, CD11b-high, CD68+, SIGNR1+, Dectin-1+.")
AnnotationAssertion(rdfs:label obo:CL_0000581 "peritoneal macrophage")
EquivalentClasses(obo:CL_0000581 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001179) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001807) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006172) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002062)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000581 obo:CL_0000864)

# Class: obo:CL_0000582 (neutrophilic metamyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:10618520") Annotation(oboInOwl:hasDbXref "PMID:12560239") Annotation(oboInOwl:hasDbXref "PMID:15514007") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000582 "A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000582 "FMA:84197")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000582 "juvenile neutrophil")
AnnotationAssertion(rdfs:comment obo:CL_0000582 "These cells are also CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction.")
AnnotationAssertion(rdfs:label obo:CL_0000582 "neutrophilic metamyelocyte")
EquivalentClasses(obo:CL_0000582 ObjectIntersectionOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005310) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009725) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009978) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001580) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000582 obo:CL_0000776)
SubClassOf(obo:CL_0000582 obo:CL_0002192)
SubClassOf(obo:CL_0000582 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000580))

# Class: obo:CL_0000583 (alveolar macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "MESH:D016676") obo:IAO_0000115 obo:CL_0000583 "A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000583 "BTO:0000802")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000583 "CALOHA:TS-0030")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000583 "FMA:83023")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000583 "dust cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000583 "MF.Lu")
AnnotationAssertion(rdfs:comment obo:CL_0000583 "Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-.")
AnnotationAssertion(rdfs:label obo:CL_0000583 "alveolar macrophage")
EquivalentClasses(obo:CL_0000583 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001206) ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_8850000) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001807) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000583 obo:CL_0000864)
SubClassOf(obo:CL_0000583 obo:CL_1001603)

# Class: obo:CL_0000584 (enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000584 "An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000584 "BTO:0000398")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000584 "FMA:62122")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000584 "MESH:D020895")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasNarrowSynonym obo:CL_0000584 "differentiated enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasNarrowSynonym obo:CL_0000584 "mature enterocyte")
AnnotationAssertion(rdfs:label obo:CL_0000584 "enterocyte")
SubClassOf(obo:CL_0000584 obo:CL_0000677)
SubClassOf(obo:CL_0000584 obo:CL_0002563)
SubClassOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903))

# Class: obo:CL_0000585 (obsolete null cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000585 "OBSOLETE: A class of lymphocytes characterized by the lack of surface markers specific for either T or B cells.")
AnnotationAssertion(rdfs:comment obo:CL_0000585 "This term is rather archaic; consider using 'natural killer cell ; CL:0000623', 'pro-B cell ; CL:0000826', 'pro-T cell ; CL:0000827', or other appropriate lymphocyte-related term depending on the context.")
AnnotationAssertion(rdfs:label obo:CL_0000585 "obsolete null cell")
AnnotationAssertion(owl:deprecated obo:CL_0000585 "true"^^xsd:boolean)

# Class: obo:CL_0000586 (germ cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D005854") obo:IAO_0000115 obo:CL_0000586 "The reproductive cell in multicellular organisms.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "BTO:0000535")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "NCIT:C12597")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "VHOG:0001534")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "WBbt:0006796")
AnnotationAssertion(rdfs:label obo:CL_0000586 "germ cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000586 obo:CL_0000039)
SubClassOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0009566))

# Class: obo:CL_0000587 (cold sensing thermoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000587 "A thermoreceptor cell that detects reduced temperatures.")
AnnotationAssertion(rdfs:label obo:CL_0000587 "cold sensing thermoreceptor cell")
SubClassOf(obo:CL_0000587 obo:CL_0000205)

# Class: obo:CL_0000588 (odontoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000588 "A specialized osteoclast associated with the absorption and removal of cementum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000588 "BTO:0002516")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000588 "FMA:83027")
AnnotationAssertion(rdfs:label obo:CL_0000588 "odontoclast")
EquivalentClasses(obo:CL_0000588 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042483)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000588 obo:CL_0000092)

# Class: obo:CL_0000589 (cochlear inner hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D006199") obo:IAO_0000115 obo:CL_0000589 "A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000589 "inner hair cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000589 "BTO:0003667")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000589 "FMA:62365")
AnnotationAssertion(rdfs:label obo:CL_0000589 "cochlear inner hair cell")
SubClassOf(obo:CL_0000589 obo:CL_4023120)

# Class: obo:CL_0000590 (small luteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D008184") obo:IAO_0000115 obo:CL_0000590 "A progesterone secreting cell in the corpus luteum that develops from theca cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000590 "BTO:0002850")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000590 "FMA:18690")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000590 "small lutein cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000590 "theca lutein cell")
AnnotationAssertion(rdfs:label obo:CL_0000590 "small luteal cell")
SubClassOf(obo:CL_0000590 obo:CL_0000175)
SubClassOf(obo:CL_0000590 obo:CL_0000179)
SubClassOf(obo:CL_0000590 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000503))

# Class: obo:CL_0000591 (warmth sensing thermoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000591 "A thermoreceptor cell that detects increased temperatures.")
AnnotationAssertion(rdfs:label obo:CL_0000591 "warmth sensing thermoreceptor cell")
SubClassOf(obo:CL_0000591 obo:CL_0000205)

# Class: obo:CL_0000592 (large luteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D008184") obo:IAO_0000115 obo:CL_0000592 "A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000592 "FMA:18689")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000592 "granulosa lutein cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000592 "granulosoluteocytus")
AnnotationAssertion(rdfs:label obo:CL_0000592 "large luteal cell")
SubClassOf(obo:CL_0000592 obo:CL_0000175)
SubClassOf(obo:CL_0000592 obo:CL_0000177)
SubClassOf(obo:CL_0000592 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000501))

# Class: obo:CL_0000593 (androgen secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000593 "A steroid hormone secreting cell that secretes androgen.")
AnnotationAssertion(rdfs:label obo:CL_0000593 "androgen secreting cell")
EquivalentClasses(obo:CL_0000593 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035935)))

# Class: obo:CL_0000594 (skeletal muscle satellite cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D032496") Annotation(oboInOwl:hasDbXref "PMID:21849021") Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0000594 "An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers.")
AnnotationAssertion(rdfs:comment obo:CL_0000594 "Skeletal muscle satellite cells are not traditionally referred to as myoblasts.  They are a heterogeneous population whose division, following activiation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle statelite cell population.")
AnnotationAssertion(rdfs:label obo:CL_0000594 "skeletal muscle satellite cell")
SubClassOf(obo:CL_0000594 obo:CL_0000680)
SubClassOf(obo:CL_0000594 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134))

# Class: obo:CL_0000595 (enucleate erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000595 "An erythrocyte lacking a nucleus.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000595 "red blood cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000595 "RBC")
AnnotationAssertion(rdfs:label obo:CL_0000595 "enucleate erythrocyte")
EquivalentClasses(obo:CL_0000595 ObjectIntersectionOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000595 obo:CL_0000232)
SubClassOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002422))

# Class: obo:CL_0000596 (sexual spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FAO:0000017") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000596 "A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000596 "FAO:0000017")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000596 "meiotically-derived spore")
AnnotationAssertion(rdfs:label obo:CL_0000596 "sexual spore")
SubClassOf(obo:CL_0000596 obo:CL_0002369)

# Class: obo:CL_0000597 (microconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0471940526") Annotation(oboInOwl:hasDbXref "PMID:8357339") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000597 "The smaller of two types of asexual spores formed by some fungi. An ovoid to pear-shaped asexual spore that contains very little cytoplasm and organelles, is uninucleate, and forms in vegetative hypae within a mycelium. Micronidia are extruded from the hyphal cell wall.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000597 "FAO:0000028")
AnnotationAssertion(rdfs:label obo:CL_0000597 "microconidium")
SubClassOf(obo:CL_0000597 obo:CL_0002381)

# Class: obo:CL_0000598 (pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D017966") obo:IAO_0000115 obo:CL_0000598 "Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000598 "BTO:0003102")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000598 "FMA:67310")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000598 "FMA:86775")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000598 "NIFSTD:sao862606388")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000598 "projection neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000598 "pyramidal cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000598 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000598 "pyramidal neuron")
EquivalentClasses(obo:CL_0000598 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070015)))
SubClassOf(obo:CL_0000598 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0000599 (conidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") Annotation(oboInOwl:hasDbXref "PMID:2524423") Annotation(oboInOwl:hasDbXref "PMID:9529886") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000599 "An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000599 "BTO:0000283")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000599 "FAO:0000024")
AnnotationAssertion(rdfs:label obo:CL_0000599 "conidium")
SubClassOf(obo:CL_0000599 obo:CL_0000605)

# Class: obo:CL_0000600 (heterokaryon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000600 "A fungal cell with two or more genetically distinct nuclei.")
AnnotationAssertion(rdfs:label obo:CL_0000600 "heterokaryon")
SubClassOf(obo:CL_0000600 obo:CL_0000228)
SubClassOf(obo:CL_0000600 obo:CL_0000521)

# Class: obo:CL_0000601 (cochlear outer hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D018072") obo:IAO_0000115 obo:CL_0000601 "A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000601 "BTO:0003666")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000601 "FMA:62366")
AnnotationAssertion(rdfs:label obo:CL_0000601 "cochlear outer hair cell")
SubClassOf(obo:CL_0000601 obo:CL_0000202)
SubClassOf(obo:CL_0000601 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002227))

# Class: obo:CL_0000602 (pressoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011311") obo:IAO_0000115 obo:CL_0000602 "A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls.")
AnnotationAssertion(rdfs:label obo:CL_0000602 "pressoreceptor cell")
SubClassOf(obo:CL_0000602 obo:CL_1000082)

# Class: obo:CL_0000603 (dikaryon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000603 "A fungal cell with two genetically distinct haploid nuclei.")
AnnotationAssertion(rdfs:label obo:CL_0000603 "dikaryon")
SubClassOf(obo:CL_0000603 obo:CL_0000227)
SubClassOf(obo:CL_0000603 obo:CL_0000600)

# Class: obo:CL_0000604 (retinal rod cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D017948") obo:IAO_0000115 obo:CL_0000604 "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000604 "BTO:0001024")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000604 "CALOHA:TS-0870")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000604 "FMA:67747")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") oboInOwl:hasRelatedSynonym obo:CL_0000604 "rod")
AnnotationAssertion(rdfs:label obo:CL_0000604 "retinal rod cell")
SubClassOf(obo:CL_0000604 obo:CL_0010009)
SubClassOf(obo:CL_0000604 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002672))

# Class: obo:CL_0000605 (fungal asexual spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:2524423") Annotation(oboInOwl:hasDbXref "PMID:9529886") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000605 "A spore formed following mitosis or mitoses.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000605 "FAO:0000023")
AnnotationAssertion(rdfs:label obo:CL_0000605 "fungal asexual spore")
SubClassOf(obo:CL_0000605 obo:CL_0002369)

# Class: obo:CL_0000606 (macroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0471940526") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000606 "The larger of two types of asexual spores formed by some fungi; usually round or oblong.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000606 "FAO:0000038")
AnnotationAssertion(rdfs:label obo:CL_0000606 "macroconidium")
SubClassOf(obo:CL_0000606 obo:CL_0000599)

# Class: obo:CL_0000607 (ascospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:08199377X") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000607 "A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000607 "BTO:0000097")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000607 "FAO:0000020")
AnnotationAssertion(rdfs:label obo:CL_0000607 "ascospore")
SubClassOf(obo:CL_0000607 obo:CL_0000596)

# Class: obo:CL_0000608 (zygospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471940526") Annotation(oboInOwl:hasDbXref "ISBN:08199377X") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0000608 "A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000608 "FAO:0000040")
AnnotationAssertion(rdfs:label obo:CL_0000608 "zygospore")
SubClassOf(obo:CL_0000608 obo:CL_0000596)

# Class: obo:CL_0000609 (vestibular hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D018069") obo:IAO_0000115 obo:CL_0000609 "A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000609 "FMA:62351")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000609 "vestibular receptor cell")
AnnotationAssertion(rdfs:label obo:CL_0000609 "vestibular hair cell")
SubClassOf(obo:CL_0000609 obo:CL_0002374)

# Class: obo:CL_0000610 (obsolete plant cell)

AnnotationAssertion(oboInOwl:consider obo:CL_0000610 "PO:0009002")
AnnotationAssertion(rdfs:comment obo:CL_0000610 "This term was obsoleted as it is redundant with PO:0009002 in the cell ontology (PO)")
AnnotationAssertion(rdfs:label obo:CL_0000610 "obsolete plant cell")
AnnotationAssertion(owl:deprecated obo:CL_0000610 "true"^^xsd:boolean)

# Class: obo:CL_0000611 (eosinophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000611 "CFU-Eo")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMCID:PMC2212039") Annotation(oboInOwl:hasDbXref "PMCID:PMC2626675") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000611 "EoP")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000611 "colony forming unit eosinophil")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000611 "eosinophil stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0000611 "These cells are CD34-positive, CD45RA-negative, CD71-negative, and lineage-negative (CD2, CD3 epsilon, CD4, CD5, CD8a, CD14, CD19, CD20, integrin alpha-M, NCAM-1, SCA-1, Ly6G, Ly76).")
AnnotationAssertion(rdfs:label obo:CL_0000611 "eosinophil progenitor cell")
EquivalentClasses(obo:CL_0000611 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000611 obo:CL_0002191)
SubClassOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557))

# Class: obo:CL_0000612 (eosinophilic myelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:19622087") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000612 "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000612 "BTO:0003454")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000612 "FMA:83542")
AnnotationAssertion(rdfs:label obo:CL_0000612 "eosinophilic myelocyte")
EquivalentClasses(obo:CL_0000612 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000612 obo:CL_0000772)
SubClassOf(obo:CL_0000612 obo:CL_0002193)

# Class: obo:CL_0000613 (basophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0000613 "A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000613 "BaP")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000613 "CFU-Bas")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000613 "basophilic stem cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000613 "colony forming unit basophil")
AnnotationAssertion(rdfs:comment obo:CL_0000613 "BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf).")
AnnotationAssertion(rdfs:label obo:CL_0000613 "basophil progenitor cell")
EquivalentClasses(obo:CL_0000613 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000016401)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000613 obo:CL_0002191)
SubClassOf(obo:CL_0000613 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002028))

# Class: obo:CL_0000614 (basophilic myelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18466030") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000614 "A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000614 "BTO:0003456")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000614 "FMA:83543")
AnnotationAssertion(rdfs:label obo:CL_0000614 "basophilic myelocyte")
EquivalentClasses(obo:CL_0000614 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000614 obo:CL_0000768)
SubClassOf(obo:CL_0000614 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000830))

# Class: obo:CL_0000615 (basidiospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:clt") Annotation(oboInOwl:hasDbXref "ISBN:0471940526") Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000615 "A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000615 "BTO:0002166")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000615 "FAO:0000021")
AnnotationAssertion(rdfs:label obo:CL_0000615 "basidiospore")
SubClassOf(obo:CL_0000615 obo:CL_0000596)

# Class: obo:CL_0000616 (obsolete sporangiospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000616 "OBSOLETE: A walled spore produced in a sporangium.")
AnnotationAssertion(rdfs:label obo:CL_0000616 "obsolete sporangiospore")
AnnotationAssertion(owl:deprecated obo:CL_0000616 "true"^^xsd:boolean)

# Class: obo:CL_0000617 (GABAergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000617 "A neuron that uses GABA as a vesicular neurotransmitter")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000617 "FMA:84788")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000617 "MESH:D059330")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000617 "WBbt:0005190")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000617 "GABA-ergic neuron")
AnnotationAssertion(rdfs:label obo:CL_0000617 "GABAergic neuron")
EquivalentClasses(obo:CL_0000617 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))
SubClassOf(obo:CL_0000617 obo:CL_0000540)

# Class: obo:CL_0000618 (sheath cell)

AnnotationAssertion(rdfs:label obo:CL_0000618 "sheath cell")
SubClassOf(obo:CL_0000618 obo:CL_0000075)

# Class: obo:CL_0000619 (supporting cell (sensu Nematoda))

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000619 "support cell (sensu Nematoda)")
AnnotationAssertion(rdfs:label obo:CL_0000619 "supporting cell (sensu Nematoda)")
SubClassOf(obo:CL_0000619 obo:CL_0000378)

# Class: obo:CL_0000620 (obsolete zoospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:08199377X") obo:IAO_0000115 obo:CL_0000620 "OBSOLETE: A sporangiospore that is motile, having flagella.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000620 "FAO:0000039")
AnnotationAssertion(rdfs:label obo:CL_0000620 "obsolete zoospore")
AnnotationAssertion(owl:deprecated obo:CL_0000620 "true"^^xsd:boolean)

# Class: obo:CL_0000621 (fusion competent myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22274696") obo:IAO_0000115 obo:CL_0000621 "A myoblast that is committed to a myotube-specific program of differentiation but not yet fused. It undergoes very limited additional proliferation. After fusion, it will take on a muscle identity specified by a `muscle founder cell` (CL:0008006).")
AnnotationAssertion(rdfs:label obo:CL_0000621 "fusion competent myoblast")
SubClassOf(obo:CL_0000621 obo:CL_0000056)
SubClassOf(obo:CL_0000621 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008003))

# Class: obo:CL_0000622 (acinar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0000622 "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000622 "FMA:83625")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000622 "MESH:D061354")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000622 "acinic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000622 "acinous cell")
AnnotationAssertion(rdfs:label obo:CL_0000622 "acinar cell")
EquivalentClasses(obo:CL_0000622 ObjectIntersectionOf(obo:CL_0000150 obo:CL_0000154 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009842)))

# Class: obo:CL_0000623 (natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:15771571") obo:IAO_0000115 obo:CL_0000623 "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000623 "large granular lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000623 "null cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "BTO:0000914")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "BTO:0004716")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "CALOHA:TS-0664")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "FMA:63147")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "FMA:83601")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "MESH:D007694")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000623 "VHOG:0001697")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000623 "NK cell")
AnnotationAssertion(rdfs:label obo:CL_0000623 "natural killer cell")
EquivalentClasses(obo:CL_0000623 ObjectIntersectionOf(obo:CL_0001067 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002228) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050776)))
SubClassOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000825))

# Class: obo:CL_0000624 (CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000624 "A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000624 "CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000624 "CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000624 "CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000624 "CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000624 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000624 obo:CL_0000791)
DisjointClasses(obo:CL_0000624 obo:CL_0000625)

# Class: obo:CL_0000625 (CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000625 "A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000625 "CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000625 "CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000625 "CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000625 "CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000625 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000625 obo:CL_0000791)

# Class: obo:CL_0000626 (olfactory granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mah") Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-018-27692-8") obo:IAO_0000115 obo:CL_0000626 "A granule cell that has a soma located in an olfactory bulb granule cell layer. An olfactory granule cell is an interneuron that lacks an axon, makes reciprocal dendro-dendritic synapses with mitral cells and tufted cells and is involved in the fine spatio-temporal tuning of the responses of these principal olfactory bulb neurons to odors.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-018-27692-8") oboInOwl:hasExactSynonym obo:CL_0000626 "olfactory bulb granule cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-018-27692-8") rdfs:comment obo:CL_0000626 "Granule cells are the most abundant neuronal population in the olfactory bulb and are continuously renewed throughout life.")
AnnotationAssertion(rdfs:label obo:CL_0000626 "olfactory granule cell")
EquivalentClasses(obo:CL_0000626 ObjectIntersectionOf(obo:CL_0000120 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005378)))
SubClassOf(obo:CL_0000626 obo:CL_0000099)
SubClassOf(obo:CL_0000626 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_1001502))
SubClassOf(obo:CL_0000626 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_1001503))
SubClassOf(obo:CL_0000626 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_1001502))
SubClassOf(obo:CL_0000626 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_1001503))
SubClassOf(obo:CL_0000626 ObjectSomeValuesFrom(obo:RO_0002428 obo:GO_0007608))

# Class: obo:CL_0000627 (obsolete transporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:sr") obo:IAO_0000115 obo:CL_0000627 "OBSOLETE. A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000627 <https://github.com/obophenotype/cell-ontology/issues/2990>)
AnnotationAssertion(rdfs:comment obo:CL_0000627 "Unsustainable functional grouping term of dubious utility.")
AnnotationAssertion(rdfs:label obo:CL_0000627 "obsolete transporting cell")
AnnotationAssertion(owl:deprecated obo:CL_0000627 "true"^^xsd:boolean)

# Class: obo:CL_0000628 (photosynthetic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:sr") obo:IAO_0000115 obo:CL_0000628 "A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source.")
AnnotationAssertion(rdfs:comment obo:CL_0000628 "see PMID:21177950, The making of a photosynthetic animal.")
AnnotationAssertion(rdfs:label obo:CL_0000628 "photosynthetic cell")
SubClassOf(obo:CL_0000628 obo:CL_0000000)
SubClassOf(obo:CL_0000628 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015979))

# Class: obo:CL_0000629 (storage cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000629 "A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose.")
AnnotationAssertion(rdfs:label obo:CL_0000629 "storage cell")
SubClassOf(obo:CL_0000629 obo:CL_0000325)

# Class: obo:CL_0000630 (supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000630 "A cell whose primary function is to support other cell types.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000630 "BTO:0002315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000630 "supportive cell")
AnnotationAssertion(rdfs:label obo:CL_0000630 "supporting cell")
SubClassOf(obo:CL_0000630 obo:CL_0000000)

# Class: obo:CL_0000631 (labyrinth supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D007760") obo:IAO_0000115 obo:CL_0000631 "Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen.")
AnnotationAssertion(rdfs:label obo:CL_0000631 "labyrinth supporting cell")
SubClassOf(obo:CL_0000631 obo:CL_0000630)

# Class: obo:CL_0000632 (hepatic stellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "MESH:D055166") Annotation(oboInOwl:hasDbXref "PMID:12808230") Annotation(oboInOwl:hasDbXref "PMID:17239632") Annotation(oboInOwl:hasDbXref "PMID:18222966") Annotation(oboInOwl:hasDbXref "PMID:9302568") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Hepatic_stellate_cell") obo:IAO_0000115 obo:CL_0000632 "A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000632 "BTO:0002741")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000632 "CALOHA:TS-0452")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000632 "FMA:67763")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000632 "Ito cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000632 "hepatic perisinusoidal cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000632 "perisinusoidal cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000632 "fat-storing cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000632 "lipocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12808230") oboInOwl:hasRelatedSynonym obo:CL_0000632 "vitamin A-storing cells")
AnnotationAssertion(rdfs:comment obo:CL_0000632 "Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen.")
AnnotationAssertion(rdfs:label obo:CL_0000632 "hepatic stellate cell")
EquivalentClasses(obo:CL_0000632 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000007939)))
SubClassOf(obo:CL_0000632 obo:CL_0000057)
SubClassOf(obo:CL_0000632 obo:CL_0000327)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000632 obo:CL_0002320)

# Class: obo:CL_0000633 (Hensen cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000633 "A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000633 "FMA:79799")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000633 "Hensen's cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000633 "cell of Hensen")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000633 "external limiting cell of organ of Corti")
AnnotationAssertion(rdfs:label obo:CL_0000633 "Hensen cell")
SubClassOf(obo:CL_0000633 obo:CL_0002490)

# Class: obo:CL_0000634 (Claudius cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000634 "A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000634 "FMA:79802")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000634 "cell of Claudius")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000634 "external supporting cell of Claudius")
AnnotationAssertion(rdfs:label obo:CL_0000634 "Claudius cell")
SubClassOf(obo:CL_0000634 obo:CL_0002315)

# Class: obo:CL_0000635 (Deiter's cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "http://www.britannica.com/EBchecked/topic/156177/Deiters-cell") obo:IAO_0000115 obo:CL_0000635 "The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000635 "FMA:75725")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000635 "Deiters cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000635 "outer phalangeal cell")
AnnotationAssertion(rdfs:label obo:CL_0000635 "Deiter's cell")
SubClassOf(obo:CL_0000635 obo:CL_0002165)

# Class: obo:CL_0000636 (Mueller cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:21911394") obo:IAO_0000115 obo:CL_0000636 "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000636 "BTO:0003064")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.21769/BioProtoc.4179") Annotation(oboInOwl:hasSynonymType core:MISSPELLING) oboInOwl:hasExactSynonym obo:CL_0000636 "Muller cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000636 "Muller glia")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000636 "Müller cell")
AnnotationAssertion(rdfs:label obo:CL_0000636 "Mueller cell")
SubClassOf(obo:CL_0000636 obo:CL_0000681)
SubClassOf(obo:CL_0000636 obo:CL_0009004)
SubClassOf(obo:CL_0000636 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966))

# Class: obo:CL_0000637 (chromophil cell of anterior pituitary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0000637 "A cell that stains readily in the anterior pituitary gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000637 "FMA:83089")
AnnotationAssertion(rdfs:label obo:CL_0000637 "chromophil cell of anterior pituitary gland")
EquivalentClasses(obo:CL_0000637 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002196)))
SubClassOf(obo:CL_0000637 obo:CL_0000150)
SubClassOf(obo:CL_0000637 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030072))

# Class: obo:CL_0000638 (acidophil cell of pars distalis of adenohypophysis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000638 "An acidophilic chromophil cell that of the anterior pituitary gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000638 "FMA:83093")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000638 "acidophil cell of pars anterior of adenohypophysis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000638 "acidophil of pars anterior of adenohypophysis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000638 "acidophil of pars distalis of adenohypophysis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000638 "pituitary alpha cell")
AnnotationAssertion(rdfs:label obo:CL_0000638 "acidophil cell of pars distalis of adenohypophysis")
SubClassOf(obo:CL_0000638 obo:CL_0000637)
SubClassOf(obo:CL_0000638 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006964))

# Class: obo:CL_0000639 (basophil cell of pars distalis of adenohypophysis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000639 "A basophilic chromophil cell that of the anterior pituitary gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000639 "FMA:83094")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000639 "basophil cell of anterior lobe of hypophysis")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000639 "beta cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000639 "pituitary beta cell")
AnnotationAssertion(rdfs:label obo:CL_0000639 "basophil cell of pars distalis of adenohypophysis")
SubClassOf(obo:CL_0000639 obo:CL_0000637)

# Class: obo:CL_0000640 (obo:CL_0000640)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000640 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000640 obo:CL_0000467)
AnnotationAssertion(owl:deprecated obo:CL_0000640 "true"^^xsd:boolean)

# Class: obo:CL_0000641 (chromophobe cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000641 "A cell that is resistant to stains.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000641 "FMA:83626")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000641 "chromophobic cell")
AnnotationAssertion(rdfs:label obo:CL_0000641 "chromophobe cell")
SubClassOf(obo:CL_0000641 obo:CL_0000163)

# Class: obo:CL_0000642 (folliculostellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:10495875") Annotation(oboInOwl:hasDbXref "PMID:15961560") Annotation(oboInOwl:hasDbXref "doi:10.23937/2572-407X.1510006") obo:IAO_0000115 obo:CL_0000642 "An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.23937/2572-407X.1510006") oboInOwl:hasExactSynonym obo:CL_0000642 "folliculo-stellate cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34734454") oboInOwl:hasExactSynonym obo:CL_0000642 "pituitary folliculostellate cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34734454") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000642 "FS cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.23937/2572-407X.1510006") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000642 "FSC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34734454") oboInOwl:hasRelatedSynonym obo:CL_0000642 "Sox2-positive stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18287078") Annotation(oboInOwl:hasDbXref "PMID:31620083") Annotation(oboInOwl:hasDbXref "PMID:34734454") Annotation(oboInOwl:hasDbXref "doi:10.23937/2572-407X.1510006") rdfs:comment obo:CL_0000642 "Folliculostellate cells are a heterogeneous group of cells rather than a single cell type, with different morphology and gene expression profiles. Due to this heterogeneity, it is unclear if different properties that have been attributed to folliculostellate cells (pluripotent, proliferative, phagocytic) are common in all folliculostellate cells or limited to particular subsets.")
AnnotationAssertion(rdfs:label obo:CL_0000642 "folliculostellate cell")
SubClassOf(obo:CL_0000642 obo:CL_0000630)
SubClassOf(obo:CL_0000642 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002196))

# Class: obo:CL_0000643 (obo:CL_0000643)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000643 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000643 obo:CL_0002085)
AnnotationAssertion(owl:deprecated obo:CL_0000643 "true"^^xsd:boolean)

# Class: obo:CL_0000644 (Bergmann glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.neurolex.org/wiki/Category:Bergmann_Glial_Cell") obo:IAO_0000115 obo:CL_0000644 "Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000644 "FMA:54559")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000644 "Bergmann astrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000644 "Bergmann glial cell of cerebellum")
AnnotationAssertion(rdfs:label obo:CL_0000644 "Bergmann glial cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0000644 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
SubClassOf(obo:CL_0000644 obo:CL_0000127)
SubClassOf(obo:CL_0000644 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002979))

# Class: obo:CL_0000645 (pituicyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:31915267") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Pituicyte") obo:IAO_0000115 obo:CL_0000645 "A glial cell of astrocytic lineage with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000645 "BTO:0003793")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000645 "FMA:83503")
AnnotationAssertion(rdfs:label obo:CL_0000645 "pituicyte")
SubClassOf(obo:CL_0000645 obo:CL_0000127)
SubClassOf(obo:CL_0000645 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002198))

# Class: obo:CL_0000646 (basal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0000646 "Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000646 "BTO:0000939")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000646 "FMA:62516")
AnnotationAssertion(rdfs:label obo:CL_0000646 "basal cell")
SubClassOf(obo:CL_0000646 obo:CL_0000036)

# Class: obo:CL_0000647 (multinucleated giant cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") Annotation(oboInOwl:hasDbXref "PMID:33348900") Annotation(oboInOwl:hasDbXref "Wikipedia:Giant_cell") obo:IAO_0000115 obo:CL_0000647 "A phagocytic syncytial cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000647 "BTO:0003107")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000647 "FMA:83035")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000647 "MESH:D015726")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") oboInOwl:hasExactSynonym obo:CL_0000647 "Langerhans giant cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") oboInOwl:hasExactSynonym obo:CL_0000647 "foreign body giant cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") oboInOwl:hasExactSynonym obo:CL_0000647 "macrophage polykaryon")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") oboInOwl:hasExactSynonym obo:CL_0000647 "multinucleate giant cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:0702024783") oboInOwl:hasExactSynonym obo:CL_0000647 "syncytial giant cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33348900") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000647 "MGC")
AnnotationAssertion(rdfs:comment obo:CL_0000647 "Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this.")
AnnotationAssertion(rdfs:label obo:CL_0000647 "multinucleated giant cell")
EquivalentClasses(obo:CL_0000647 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002432) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002544)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000647 obo:CL_0000766)
SubClassOf(obo:CL_0000647 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000235))
SubClassOf(obo:CL_0000647 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0000768))

# Class: obo:CL_0000648 (kidney granular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11457727") obo:IAO_0000115 obo:CL_0000648 "A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000648 "juxtaglomerular cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000648 "FMA:84138")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000648 "JG cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000648 "renin secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0000648 "kidney granular cell")
EquivalentClasses(obo:CL_0000648 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002113) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002001)))
SubClassOf(obo:CL_0000648 obo:CL_0000192)
SubClassOf(obo:CL_0000648 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002303))

# Class: obo:CL_0000649 (spinous cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "ISBN:0815332181") Annotation(oboInOwl:hasDbXref "PMID:21860392") Annotation(oboInOwl:hasDbXref "PMID:32097634") Annotation(oboInOwl:hasDbXref "WIKIPEDIA:Spinous_cell") obo:IAO_0000115 obo:CL_0000649 "A keratinocyte found within the stratum spinosum (prickle cell layer) of the epidermis, distinguished by numerous intercellular desmosomes, which give it a “prickly” or spiny appearance. Positioned above the mitotically active basal layer and beneath the granular layer, it contributes to the skin’s mechanical strength and barrier function, preventing water loss and pathogen entry. This cell expresses differentiation-specific keratins K1 and K10 in mice, unlike basal cells that express K5 and K14, and lacks the keratohyalin granules found in granular cells, marking its intermediate stage of epidermal differentiation.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000649 "FMA:69059")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WIKIPEDIA:Spinous_cell") oboInOwl:hasExactSynonym obo:CL_0000649 "prickle cell of epidermis")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32843640") oboInOwl:hasExactSynonym obo:CL_0000649 "spinous keratinocytes of epidermis")
AnnotationAssertion(rdfs:label obo:CL_0000649 "spinous cell of epidermis")
EquivalentClasses(obo:CL_0000649 ObjectIntersectionOf(obo:CL_4052060 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002026)))
SubClassOf(obo:CL_0000649 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001365))

# Class: obo:CL_0000650 (mesangial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells") obo:IAO_0000115 obo:CL_0000650 "A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000650 "BTO:0000853")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000650 "CALOHA:TS-0617")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000650 "FMA:70972")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000650 "MESH:D050527")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000650 "kidney mesangial cell")
AnnotationAssertion(rdfs:comment obo:CL_0000650 "Do all of these cells really develop from some mesenchymal stem cell?")
AnnotationAssertion(rdfs:label obo:CL_0000650 "mesangial cell")
SubClassOf(obo:CL_0000650 obo:CL_0000669)
SubClassOf(obo:CL_0000650 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002319))
SubClassOf(obo:CL_0000650 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134))

# Class: obo:CL_0000651 (obsolete mucous neck cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000651 "OBSOLETE. A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000651 obo:CL_0002181)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000651 "neck cell")
AnnotationAssertion(rdfs:comment obo:CL_0000651 "duplicate term")
AnnotationAssertion(rdfs:label obo:CL_0000651 "obsolete mucous neck cell")
AnnotationAssertion(owl:deprecated obo:CL_0000651 "true"^^xsd:boolean)

# Class: obo:CL_0000652 (pinealocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:16687276") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Pinealocyte") obo:IAO_0000115 obo:CL_0000652 "This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000652 "BTO:0001068")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000652 "FMA:83417")
AnnotationAssertion(rdfs:label obo:CL_0000652 "pinealocyte")
SubClassOf(obo:CL_0000652 obo:CL_0000163)
SubClassOf(obo:CL_0000652 obo:CL_0000710)
SubClassOf(obo:CL_0000652 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001905))
SubClassOf(obo:CL_0000652 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030187))

# Class: obo:CL_0000653 (podocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1101/2021.10.10.463829") obo:IAO_0000115 obo:CL_0000653 "A specialized kidney epithelial cell, contained within a glomerulus, that contains \"feet\" that interdigitate with the \"feet\" of other podocytes.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70967") oboInOwl:hasBroadSynonym obo:CL_0000653 "epithelial cell of visceral layer of glomerular capsule")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000653 "BTO:0002295")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000653 "FMA:70967")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70967") oboInOwl:hasExactSynonym obo:CL_0000653 "glomerular podocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000653 "glomerular visceral epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000653 "kidney podocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000653 "renal podocyte")
AnnotationAssertion(rdfs:label obo:CL_0000653 "podocyte")
AnnotationAssertion(rdfs:seeAlso obo:CL_0000653 "https://github.com/obophenotype/cell-ontology/issues/1460")
EquivalentClasses(obo:CL_0000653 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005751)))
SubClassOf(obo:CL_0000653 obo:CL_0002522)

# Class: obo:CL_0000654 (primary oocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000654 "A primary oocyte is an oocyte that has not completed female meosis I.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000654 "BTO:0000512")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000654 "FMA:18645")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000654 "primary oogonium")
AnnotationAssertion(rdfs:label obo:CL_0000654 "primary oocyte")
EquivalentClasses(obo:CL_0000654 ObjectIntersectionOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0051321)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000654 obo:CL_0000023)
SubClassOf(obo:CL_0000654 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000024))

# Class: obo:CL_0000655 (secondary oocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000655 "A secondary oocyte is an oocyte that has not completed meiosis II.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000655 "BTO:0003094")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000655 "FMA:18646")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000655 "primary oogonium")
AnnotationAssertion(rdfs:label obo:CL_0000655 "secondary oocyte")
EquivalentClasses(obo:CL_0000655 ObjectIntersectionOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0007147)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000655 obo:CL_0000023)
SubClassOf(obo:CL_0000655 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000654))

# Class: obo:CL_0000656 (primary spermatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000656 "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000656 "BTO:0001115")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000656 "CALOHA:TS-2194")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000656 "FMA:72292")
AnnotationAssertion(rdfs:label obo:CL_0000656 "primary spermatocyte")
EquivalentClasses(obo:CL_0000656 ObjectIntersectionOf(obo:CL_0000017 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001394) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007140)))

# Class: obo:CL_0000657 (secondary spermatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000657 "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000657 "BTO:0000709")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000657 "CALOHA:TS-2195")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000657 "FMA:72293")
AnnotationAssertion(rdfs:label obo:CL_0000657 "secondary spermatocyte")
EquivalentClasses(obo:CL_0000657 ObjectIntersectionOf(obo:CL_0000017 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007142)))
SubClassOf(obo:CL_0000657 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000656))

# Class: obo:CL_0000658 (cuticle secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000658 "An epithelial cell that secretes cuticle.")
AnnotationAssertion(rdfs:label obo:CL_0000658 "cuticle secreting cell")
SubClassOf(obo:CL_0000658 obo:CL_0000066)
SubClassOf(obo:CL_0000658 obo:CL_0000327)

# Class: obo:CL_0000659 (eggshell secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000659 "An extracellular matrix secreting cell that secretes eggshell.")
AnnotationAssertion(rdfs:label obo:CL_0000659 "eggshell secreting cell")
SubClassOf(obo:CL_0000659 obo:CL_0000327)
SubClassOf(obo:CL_0000659 obo:CL_0000500)

# Class: obo:CL_0000660 (glycocalyx secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000660 "An extracellular matrix secreting cell that secretes glycocalyx.")
AnnotationAssertion(rdfs:label obo:CL_0000660 "glycocalyx secreting cell")
SubClassOf(obo:CL_0000660 obo:CL_0000327)

# Class: obo:CL_0000661 (distal tip cell (sensu Nematoda))

AnnotationAssertion(rdfs:label obo:CL_0000661 "distal tip cell (sensu Nematoda)")
SubClassOf(obo:CL_0000661 obo:CL_0000422)

# Class: obo:CL_0000662 (neuroglioblast (sensu Nematoda))

AnnotationAssertion(rdfs:label obo:CL_0000662 "neuroglioblast (sensu Nematoda)")
SubClassOf(obo:CL_0000662 obo:CL_0000468)

# Class: obo:CL_0000663 (obsolete valve cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000663 <https://github.com/obophenotype/cell-ontology/issues/726>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000663 obo:CL_1000147)
AnnotationAssertion(rdfs:label obo:CL_0000663 "obsolete valve cell")
AnnotationAssertion(owl:deprecated obo:CL_0000663 "true"^^xsd:boolean)

# Class: obo:CL_0000664 (obsolete closable valve cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000664 <https://github.com/obophenotype/cell-ontology/issues/726>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000664 obo:CL_1000147)
AnnotationAssertion(rdfs:label obo:CL_0000664 "obsolete closable valve cell")
AnnotationAssertion(owl:deprecated obo:CL_0000664 "true"^^xsd:boolean)

# Class: obo:CL_0000665 (obsolete permanently open valve cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000665 <https://github.com/obophenotype/cell-ontology/issues/726>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000665 obo:CL_1000147)
AnnotationAssertion(rdfs:label obo:CL_0000665 "obsolete permanently open valve cell")
AnnotationAssertion(owl:deprecated obo:CL_0000665 "true"^^xsd:boolean)

# Class: obo:CL_0000666 (fenestrated endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1007/978-3-211-99390-3_133") obo:IAO_0000115 obo:CL_0000666 "An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000666 "window cell")
AnnotationAssertion(rdfs:label obo:CL_0000666 "fenestrated endothelial cell")
EquivalentClasses(obo:CL_0000666 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064)))
SubClassOf(obo:CL_0000666 obo:CL_0000115)

# Class: obo:CL_0000667 (collagen secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000667 "An extracellular matrix secreting cell that secretes collagen.")
AnnotationAssertion(rdfs:label obo:CL_0000667 "collagen secreting cell")
SubClassOf(obo:CL_0000667 obo:CL_0000327)

# Class: obo:CL_0000668 (obsolete parenchymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000668 "OBSOLETE: The cell characteristic of an organ, as distinguished from associated connective or supporting tissues.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000668 "BTO:0002174")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000668 "FMA:84638")
AnnotationAssertion(rdfs:comment obo:CL_0000668 "OBSOLETE: Term was made obsolete to avoid confusion with plant parenchymal cell. Cell type has a similar but slightly different meaning in botany (plants): see PO:0000074.")
AnnotationAssertion(rdfs:label obo:CL_0000668 "obsolete parenchymal cell")
AnnotationAssertion(owl:deprecated obo:CL_0000668 "true"^^xsd:boolean)

# Class: obo:CL_0000669 (pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "MESH:D020286") Annotation(oboInOwl:hasDbXref "PMID:16807374") Annotation(oboInOwl:hasDbXref "PMID:17986482") Annotation(oboInOwl:hasDbXref "PMID:20024907") obo:IAO_0000115 obo:CL_0000669 "An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000669 "BTO:0002441")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000669 "FMA:63174")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17986482") oboInOwl:hasExactSynonym obo:CL_0000669 "ARC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000669 "adventitial reticular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000669 "cell of Rouget")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000669 "pericyte cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000669 "pericyte of Rouget")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000669 "adventitial cell")
AnnotationAssertion(rdfs:comment obo:CL_0000669 "Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.")
AnnotationAssertion(rdfs:label obo:CL_0000669 "pericyte")
SubClassOf(obo:CL_0000669 obo:CL_0000183)
SubClassOf(obo:CL_0000669 obo:CL_0000630)
SubClassOf(obo:CL_0000669 obo:CL_0002320)
SubClassOf(obo:CL_0000669 obo:CL_0008034)

# Class: obo:CL_0000670 (primordial germ cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1381289") obo:IAO_0000115 obo:CL_0000670 "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000670 "FMA:70567")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000670 "gonocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000670 "primitive germ cell")
AnnotationAssertion(rdfs:label obo:CL_0000670 "primordial germ cell")
EquivalentClasses(obo:CL_0000670 ObjectIntersectionOf(obo:CL_0000039 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048870)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000670 obo:CL_0000039)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000670 obo:CL_0000219)

# Class: obo:CL_0000671 (centripetally migrating follicle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36807509") obo:IAO_0000115 obo:CL_0000671 "A follicle cell that migrates from the dorso-anterior part of the oocyte associated follicular epithelium, in between the nurse cells and the oocyte, and participates in the formation of the operculum.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000671 "centripetal follicle cell")
AnnotationAssertion(rdfs:label obo:CL_0000671 "centripetally migrating follicle cell")
SubClassOf(obo:CL_0000671 obo:CL_0000477)

# Class: obo:CL_0000672 (obsolete tracheary element)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0471245208") obo:IAO_0000115 obo:CL_0000672 "Obsolete. Use PO:0000290 from Plant Ontology instead. A water conducting cell, tracheid or vessel member.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000672 obo:PO_0000290)
AnnotationAssertion(rdfs:label obo:CL_0000672 "obsolete tracheary element")
AnnotationAssertion(owl:deprecated obo:CL_0000672 "true"^^xsd:boolean)

# Class: obo:CL_0000673 (Kenyon cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/S1467-8039(03)00009-4") obo:IAO_0000115 obo:CL_0000673 "An intrinsic neuron of the mushroom body of arthropods and annelids. They have tightly packed, cytoplasm-poor cell bodies.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000673 "mushroom body intrinsic neuron")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000673 "globuli cell")
AnnotationAssertion(rdfs:label obo:CL_0000673 "Kenyon cell")
SubClassOf(obo:CL_0000673 obo:CL_0000028)
SubClassOf(obo:CL_0000673 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001058))

# Class: obo:CL_0000674 (interfollicle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36531940") obo:IAO_0000115 obo:CL_0000674 "A follicle cell that is part of the stalk connecting adjacent egg chambers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000674 "stalk cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000674 "stalk follicle cell")
AnnotationAssertion(rdfs:label obo:CL_0000674 "interfollicle cell")
SubClassOf(obo:CL_0000674 obo:CL_0000477)

# Class: obo:CL_0000675 (female gamete)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000675 "A mature sexual reproductive cell of the female germline.")
AnnotationAssertion(rdfs:label obo:CL_0000675 "female gamete")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000675 obo:CL_0000021)
SubClassOf(obo:CL_0000675 obo:CL_0000300)

# Class: obo:CL_0000676 (cap cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000676 "BTO:0001033")
AnnotationAssertion(rdfs:label obo:CL_0000676 "cap cell")
SubClassOf(obo:CL_0000676 obo:CL_0000378)

# Class: obo:CL_0000677 (gut absorptive cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000677 "Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules.")
AnnotationAssertion(rdfs:label obo:CL_0000677 "gut absorptive cell")
SubClassOf(obo:CL_0000677 obo:CL_0000000)
SubClassOf(obo:CL_0000677 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))

# Class: obo:CL_0000678 (commissural neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17560562") Annotation(oboInOwl:hasDbXref "PMID:31693445") obo:IAO_0000115 obo:CL_0000678 "A neuron with soma location in the central nervous system that project its axon to the contralateral side of a central nervous system. This neuron can have its soma in the spinal cord, in the hemisphere of the brain, in the retina or in the ventral nerve cord of invertebrates.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25960414") Annotation(oboInOwl:hasDbXref "PMID:27532244") Annotation(oboInOwl:hasDbXref "PMID:31514748") Annotation(oboInOwl:hasDbXref "PMID:33438755") rdfs:comment obo:CL_0000678 "Historically, commissural neurons, particularly in the spinal cord, have been used as a model to understand axon guidance during development.")
AnnotationAssertion(rdfs:label obo:CL_0000678 "commissural neuron")
SubClassOf(obo:CL_0000678 obo:CL_0000540)
SubClassOf(obo:CL_0000678 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0000679 (glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000679 "A neuron that is capable of some neurotansmission by glutamate secretion.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000679 "WBbt:0006829")
AnnotationAssertion(rdfs:label obo:CL_0000679 "glutamatergic neuron")
EquivalentClasses(obo:CL_0000679 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535)))
SubClassOf(obo:CL_0000679 obo:CL_0000540)

# Class: obo:CL_0000680 (muscle precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000680 "A non-terminally differentiated cell that is capable of developing into a muscle cell.")
AnnotationAssertion(rdfs:label obo:CL_0000680 "muscle precursor cell")
EquivalentClasses(obo:CL_0000680 ObjectIntersectionOf(obo:CL_0011115 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000187)))
SubClassOf(obo:CL_0000680 obo:CL_0011026)
SubClassOf(obo:CL_0000680 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0000681 (radial glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dph") obo:IAO_0000115 obo:CL_0000681 "A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration.")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000681 "forebrain radial glial cell")
AnnotationAssertion(rdfs:comment obo:CL_0000681 "Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of
radial glial cells acting as neural progenitors throughout life.")
AnnotationAssertion(rdfs:label obo:CL_0000681 "radial glial cell")
SubClassOf(obo:CL_0000681 obo:CL_0000125)
SubClassOf(obo:CL_0000681 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000710))

# Class: obo:CL_0000682 (M cell of gut)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:jb") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000682 "An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000682 "M cell"@en)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000682 "BTO:0003600")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000682 "FMA:62929")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000682 "M-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000682 "microfold cell")
AnnotationAssertion(rdfs:comment obo:CL_0000682 "Should double check and see if M cells are particular to a specific region.")
AnnotationAssertion(rdfs:label obo:CL_0000682 "M cell of gut")
SubClassOf(obo:CL_0000682 obo:CL_0000066)
SubClassOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004693))

# Class: obo:CL_0000683 (ependymoglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "http://neurolex.org/wiki/Category:Ependymoglial_Cell") obo:IAO_0000115 obo:CL_0000683 "A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000683 "MESH:D063928")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000683 "ependymal astrocyte")
AnnotationAssertion(rdfs:label obo:CL_0000683 "ependymoglial cell")
SubClassOf(obo:CL_0000683 obo:CL_0000065)

# Class: obo:CL_0000684 (littoral cell of liver)

AnnotationAssertion(rdfs:label obo:CL_0000684 "littoral cell of liver")
SubClassOf(obo:CL_0000684 obo:CL_0000077)
SubClassOf(obo:CL_0000684 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107))

# Class: obo:CL_0000685 (obsolete meristematic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PO:0004010") obo:IAO_0000115 obo:CL_0000685 "Obsolete. Use PO:0004010 from Plant Ontology instead. A cell synthesizing protoplasm and producing new cells by division and with only a primary cell wall.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000685 obo:PO_0004010)
AnnotationAssertion(rdfs:label obo:CL_0000685 "obsolete meristematic cell")
AnnotationAssertion(owl:deprecated obo:CL_0000685 "true"^^xsd:boolean)

# Class: obo:CL_0000686 (cerebrospinal fluid secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000686 "A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid.")
AnnotationAssertion(rdfs:label obo:CL_0000686 "cerebrospinal fluid secreting cell")
EquivalentClasses(obo:CL_0000686 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0033326)))
SubClassOf(obo:CL_0000686 obo:CL_0000075)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000686 obo:CL_0000151)
SubClassOf(obo:CL_0000686 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0000687 (R1 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000687 "R1 cell")
AnnotationAssertion(rdfs:label obo:CL_0000687 "R1 photoreceptor cell")
SubClassOf(obo:CL_0000687 obo:CL_0000488)
SubClassOf(obo:CL_0000687 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000688 (perijunctional fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000688 "A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina.")
AnnotationAssertion(rdfs:label obo:CL_0000688 "perijunctional fibroblast")
SubClassOf(obo:CL_0000688 obo:CL_0000057)
SubClassOf(obo:CL_0000688 obo:CL_0000630)

# Class: obo:CL_0000689 (myoendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000689 "A cell with both myofibrils and secretory granules.")
AnnotationAssertion(rdfs:label obo:CL_0000689 "myoendocrine cell")
SubClassOf(obo:CL_0000689 obo:CL_0000163)

# Class: obo:CL_0000690 (R2 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000690 "R2 cell")
AnnotationAssertion(rdfs:label obo:CL_0000690 "R2 photoreceptor cell")
SubClassOf(obo:CL_0000690 obo:CL_0000488)
SubClassOf(obo:CL_0000690 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000691 (stellate interneuron)

AnnotationAssertion(oboInOwl:inSubset obo:CL_0000691 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000691 "stellate interneuron")
EquivalentClasses(obo:CL_0000691 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070010)))

# Class: obo:CL_0000692 (terminal Schwann cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:16136171") obo:IAO_0000115 obo:CL_0000692 "A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000692 "Schwann cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18803315") oboInOwl:hasExactSynonym obo:CL_0000692 "perisynaptic Schwann cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18803315") oboInOwl:hasExactSynonym obo:CL_0000692 "teloglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18803315") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000692 "tSC")
AnnotationAssertion(rdfs:label obo:CL_0000692 "terminal Schwann cell")
SubClassOf(obo:CL_0000692 obo:CL_0000630)
SubClassOf(obo:CL_0000692 obo:CL_0002376)

# Class: obo:CL_0000693 (neurogliaform cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:17122314") obo:IAO_0000115 obo:CL_0000693 "An interneuron that has spider-like appearance with a small round soma, a large number (7-10) of short, smooth, or slightly beaded primary dendrites that give rise to only a few secondary branches, and a branched axon that establishes a dense axonal mesh with thin shafts.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18568015") oboInOwl:hasExactSynonym obo:CL_0000693 "NGF cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3235828") oboInOwl:hasExactSynonym obo:CL_0000693 "neuroglioform cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000693 "spiderweb cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0000693 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_0000693 "neurogliaform cell")
EquivalentClasses(obo:CL_0000693 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070001)))

# Class: obo:CL_0000694 (R3 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000694 "R3 cell")
AnnotationAssertion(rdfs:label obo:CL_0000694 "R3 photoreceptor cell")
SubClassOf(obo:CL_0000694 obo:CL_0000488)
SubClassOf(obo:CL_0000694 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000695 (Cajal-Retzius cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10600995") Annotation(oboInOwl:hasDbXref "PMID:34047341") Annotation(oboInOwl:hasDbXref "PMID:36774666") Annotation(oboInOwl:hasDbXref "PMID:37775311") Annotation(oboInOwl:hasDbXref "PMID:9728912") obo:IAO_0000115 obo:CL_0000695 "A type of transient, early-born glutamatergic neuron located primarily in the marginal zone (future layer I) of the developing cerebral cortex and hippocampus in vertebrates. it is characterized by a bipolar morphology with an elongated soma, a single thick dendrite oriented toward the pial surface, and a long, thin axon that extends tangentially to form horizontal plexuses across the cortical surface. It is important for the multiple developmental processes including migration, dendritogenesis and synaptogenesis. It typically undergoes programmed cell death following cortical maturation with species- and region specific patterns of survival. In mice, it is predominantly observed in the hippocampal formation, particularly in the stratum lacunosum-moleculare and outer molecular layer of the dentate gyrus (van Bruggen et al., 2023). In contrast, in humans, a second morphologically distinct subpopulation emerges mid-gestation and persists postnatally, with surviving cells observed in the cortical sulci and the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_0000695 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cajal–Retzius_cell&oldid=1032081753") oboInOwl:hasExactSynonym obo:CL_0000695 "CR cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cajal–Retzius_cell&oldid=1032081753") oboInOwl:hasExactSynonym obo:CL_0000695 "Horizontal cells of Cajal")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10600995") rdfs:comment obo:CL_0000695 "While previously called 'pioneer neurons' of the marginal zone, Cajal-Retzius cells are differentiated from pioneer neurons (which are Reln-negative) by their Reln-immunoreactivity.")
AnnotationAssertion(rdfs:label obo:CL_0000695 "Cajal-Retzius cell")
SubClassOf(obo:CL_0000695 obo:CL_0000679)
SubClassOf(obo:CL_0000695 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070006))
SubClassOf(obo:CL_0000695 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001890))
SubClassOf(obo:CL_0000695 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535))

# Class: obo:CL_0000696 (PP cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0000696 "A cell that stores and secretes pancreatic polypeptide hormone.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000696 "FMA:62938")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000696 "FMA:83409")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000696 "type F enteroendocrine cell")
AnnotationAssertion(rdfs:label obo:CL_0000696 "PP cell")
SubClassOf(obo:CL_0000696 obo:CL_0000164)
SubClassOf(obo:CL_0000696 obo:CL_0000167)

# Class: obo:CL_0000697 (R4 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000697 "R4 cell")
AnnotationAssertion(rdfs:label obo:CL_0000697 "R4 photoreceptor cell")
SubClassOf(obo:CL_0000697 obo:CL_0000488)
SubClassOf(obo:CL_0000697 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000698 (obsolete paraganglial cell)

AnnotationAssertion(rdfs:label obo:CL_0000698 "obsolete paraganglial cell")
AnnotationAssertion(owl:deprecated obo:CL_0000698 "true"^^xsd:boolean)

# Class: obo:CL_0000699 (paraganglial type 1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000699 "A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines.")
AnnotationAssertion(rdfs:label obo:CL_0000699 "paraganglial type 1 cell")
SubClassOf(obo:CL_0000699 obo:CL_0000165)

# Class: obo:CL_0000700 (dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dhill") obo:IAO_0000115 obo:CL_0000700 "A neuron that releases dopamine as a neurotransmitter.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000700 "BTO:0004032")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000700 "FMA:84787")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000700 "MESH:D059290")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000700 "WBbt:0006746")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000700 "dopaminergic cell")
AnnotationAssertion(rdfs:label obo:CL_0000700 "dopaminergic neuron")
EquivalentClasses(obo:CL_0000700 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527)))
SubClassOf(obo:CL_0000700 obo:CL_0000540)
SubClassOf(obo:CL_0000700 obo:CL_4033050)

# Class: obo:CL_0000701 (paraganglia type 2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000701 "Supports paraganglial type 1 cell.")
AnnotationAssertion(rdfs:label obo:CL_0000701 "paraganglia type 2 cell")
SubClassOf(obo:CL_0000701 obo:CL_0000630)

# Class: obo:CL_0000702 (R5 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000702 "R5 cell")
AnnotationAssertion(rdfs:label obo:CL_0000702 "R5 photoreceptor cell")
SubClassOf(obo:CL_0000702 obo:CL_0000488)
SubClassOf(obo:CL_0000702 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000703 (sustentacular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000703 "Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000703 "BTO:0002315")
AnnotationAssertion(rdfs:label obo:CL_0000703 "sustentacular cell")
SubClassOf(obo:CL_0000703 obo:CL_0000630)

# Class: obo:CL_0000704 (endothelial tip cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15376331") obo:IAO_0000115 obo:CL_0000704 "A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels.")
AnnotationAssertion(rdfs:label obo:CL_0000704 "endothelial tip cell")
SubClassOf(obo:CL_0000704 obo:CL_0000071)

# Class: obo:CL_0000705 (R6 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000705 "R6 cell")
AnnotationAssertion(rdfs:label obo:CL_0000705 "R6 photoreceptor cell")
SubClassOf(obo:CL_0000705 obo:CL_0000488)
SubClassOf(obo:CL_0000705 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000706 (choroid plexus epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "JB:jb") Annotation(oboInOwl:hasDbXref "PMID:15561411") Annotation(oboInOwl:hasDbXref "PMID:9550134") obo:IAO_0000115 obo:CL_0000706 "A specialized ependymal cell that is part of the choroid plexus epithelium, responsible for producing cerebrospinal fluid (CSF) by selectively filtering and modifying blood plasma components before secreting it into the brain and spinal cord. This cell is characterized by a brush border on its apical surface, which enhances the secretion of CSF.")
AnnotationAssertion(terms:date obo:CL_0000706 "2023-08-04T08:48:30Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") oboInOwl:hasBroadSynonym obo:CL_0000706 "choroid plexus cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000706 "FMA:70549")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000706 "epithelial cell of choroid plexus")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25729351") rdfs:comment obo:CL_0000706 "A choroid plexus epithelial cell possesses non-motile 9+0 cilia. While these cilia can exhibit transient motility during development, they generally do not contribute significantly to the directional flow of cerebrospinal fluid (CSF). Instead, they are primarily involved in sensory functions.")
AnnotationAssertion(rdfs:label obo:CL_0000706 "choroid plexus epithelial cell")
EquivalentClasses(obo:CL_0000706 ObjectIntersectionOf(obo:CL_0000065 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003911)))
SubClassOf(obo:CL_0000706 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903))
SubClassOf(obo:CL_0000706 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0033326))

# Class: obo:CL_0000707 (R7 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000707 "R7 cell")
AnnotationAssertion(rdfs:label obo:CL_0000707 "R7 photoreceptor cell")
SubClassOf(obo:CL_0000707 obo:CL_0000494)
SubClassOf(obo:CL_0000707 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000708 (leptomeningeal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000708 "Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000708 "leptomemingeal cell")
AnnotationAssertion(rdfs:label obo:CL_0000708 "leptomeningeal cell")
EquivalentClasses(obo:CL_0000708 ObjectIntersectionOf(obo:CL_0000327 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003210)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000708 obo:CL_0000327)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000708 obo:CL_0002320)

# Class: obo:CL_0000709 (R8 photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000709 "R8 cell")
AnnotationAssertion(rdfs:label obo:CL_0000709 "R8 photoreceptor cell")
SubClassOf(obo:CL_0000709 obo:CL_0000488)
SubClassOf(obo:CL_0000709 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000710 (neurecto-epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000710 "Epithelial cells derived from neural plate and neural crest.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000710 "neuroepithelial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000710 "BTO:0004301")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000710 "FMA:70557")
AnnotationAssertion(rdfs:comment obo:CL_0000710 "The term \"neuroepithelial cell\" is used to describe both this cell type and sensory epithelial cell (CL:0000098).")
AnnotationAssertion(rdfs:label obo:CL_0000710 "neurecto-epithelial cell")
EquivalentClasses(obo:CL_0000710 ObjectIntersectionOf(obo:CL_0002077 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133)))
SubClassOf(obo:CL_0000710 obo:CL_0000075)

# Class: obo:CL_0000711 (cumulus granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.org/cope.cgi?key=cumulus%20cells") obo:IAO_0000115 obo:CL_0000711 "Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000711 "BTO:0002236")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000711 "MESH:D054885")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000711 "cumulus cell")
AnnotationAssertion(rdfs:label obo:CL_0000711 "cumulus granulosa cell")
SubClassOf(obo:CL_0000711 obo:CL_0000154)
SubClassOf(obo:CL_0000711 obo:CL_0000501)
SubClassOf(obo:CL_0000711 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4033084))

# Class: obo:CL_0000712 (stratum granulosum cell)

AnnotationAssertion(rdfs:label obo:CL_0000712 "stratum granulosum cell")
EquivalentClasses(obo:CL_0000712 ObjectIntersectionOf(obo:CL_0000362 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002069)))
SubClassOf(obo:CL_0000712 obo:CL_0000362)
SubClassOf(obo:CL_0000712 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))

# Class: obo:CL_0000713 (corona radiata cell)

AnnotationAssertion(rdfs:label obo:CL_0000713 "corona radiata cell")
SubClassOf(obo:CL_0000713 obo:CL_0000711)

# Class: obo:CL_0000714 (obo:CL_0000714)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000714 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000714 obo:CL_0000513)
AnnotationAssertion(owl:deprecated obo:CL_0000714 "true"^^xsd:boolean)

# Class: obo:CL_0000715 (embryonic crystal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000715 "A crystal cell that derives from the embryonic head mesoderm.")
AnnotationAssertion(rdfs:label obo:CL_0000715 "embryonic crystal cell")
SubClassOf(obo:CL_0000715 obo:CL_0000392)
SubClassOf(obo:CL_0000715 obo:CL_0011008)

# Class: obo:CL_0000716 (lymph gland crystal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000716 "A crystal cell that derives from the larval lymph gland.")
AnnotationAssertion(rdfs:label obo:CL_0000716 "lymph gland crystal cell")
SubClassOf(obo:CL_0000716 obo:CL_0000392)
SubClassOf(obo:CL_0000716 obo:CL_0000735)

# Class: obo:CL_0000717 (obsolete fusimotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15582775") obo:IAO_0000115 obo:CL_0000717 "OBSOLETE. A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0000717 <https://github.com/obophenotype/cell-ontology/issues/1364>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000717 obo:CL_0008037)
AnnotationAssertion(rdfs:comment obo:CL_0000717 "Term merged into CL:0008037.")
AnnotationAssertion(rdfs:label obo:CL_0000717 "obsolete fusimotor neuron")
AnnotationAssertion(owl:deprecated obo:CL_0000717 "true"^^xsd:boolean)

# Class: obo:CL_0000718 (compound eye cone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34343526") Annotation(oboInOwl:hasDbXref "doi:10.1017/CBO9780511818202.023") obo:IAO_0000115 obo:CL_0000718 "A cell of an ommatidium that secretes lens materials.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000718 "Semper cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000718 "cone cell (sensu Endopterygota)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1242/jcs.s3-105.71.331") rdfs:comment obo:CL_0000718 "Not to be confused with the Semper cells of the Semper organ found in gastropods.")
AnnotationAssertion(rdfs:label obo:CL_0000718 "compound eye cone cell")
SubClassOf(obo:CL_0000718 obo:CL_0000306)
SubClassOf(obo:CL_0000718 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000971))

# Class: obo:CL_0000719 (posterior cone cell (sensu Endopterygota))

AnnotationAssertion(rdfs:label obo:CL_0000719 "posterior cone cell (sensu Endopterygota)")
SubClassOf(obo:CL_0000719 obo:CL_0000718)

# Class: obo:CL_0000720 (anterior cone cell (sensu Endopterygota))

AnnotationAssertion(rdfs:label obo:CL_0000720 "anterior cone cell (sensu Endopterygota)")
SubClassOf(obo:CL_0000720 obo:CL_0000718)

# Class: obo:CL_0000721 (equatorial cone cell (sensu Endopterygota))

AnnotationAssertion(rdfs:label obo:CL_0000721 "equatorial cone cell (sensu Endopterygota)")
SubClassOf(obo:CL_0000721 obo:CL_0000718)

# Class: obo:CL_0000722 (cystoblast)

AnnotationAssertion(rdfs:label obo:CL_0000722 "cystoblast")
SubClassOf(obo:CL_0000722 obo:CL_0000586)
SubClassOf(obo:CL_0000722 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6656))

# Class: obo:CL_0000723 (somatic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0048103") obo:IAO_0000115 obo:CL_0000723 "A stem cell that can give rise to cell types of the body other than those of the germ-line.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000723 "CALOHA:TS-2086")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000723 "MESH:D053687")
AnnotationAssertion(rdfs:label obo:CL_0000723 "somatic stem cell")
EquivalentClasses(obo:CL_0000723 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048103)))

# Class: obo:CL_0000724 (heterocyst)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MA:ma") obo:IAO_0000115 obo:CL_0000724 "A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000724 "BTO:0000600")
AnnotationAssertion(rdfs:label obo:CL_0000724 "heterocyst")
SubClassOf(obo:CL_0000724 obo:CL_0000520)
SubClassOf(obo:CL_0000724 obo:CL_0000725)

# Class: obo:CL_0000725 (nitrogen fixing cell)

AnnotationAssertion(rdfs:label obo:CL_0000725 "nitrogen fixing cell")
EquivalentClasses(obo:CL_0000725 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009399)))

# Class: obo:CL_0000726 (chlamydospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:085199377X") obo:IAO_0000115 obo:CL_0000726 "An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material.")
AnnotationAssertion(rdfs:comment obo:CL_0000726 "Considering obsoleting as sometimes used to refer to protozoans too. But reference indicates term was intended for fungus.")
AnnotationAssertion(rdfs:label obo:CL_0000726 "chlamydospore")
SubClassOf(obo:CL_0000726 obo:CL_0000605)

# Class: obo:CL_0000727 (obsolete primary pigment cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000727 <https://github.com/obophenotype/cell-ontology/issues/1930>)
AnnotationAssertion(rdfs:comment obo:CL_0000727 "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to primary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004231.")
AnnotationAssertion(rdfs:label obo:CL_0000727 "obsolete primary pigment cell")
AnnotationAssertion(owl:deprecated obo:CL_0000727 "true"^^xsd:boolean)

# Class: obo:CL_0000728 (obsolete secondary pigment cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000728 <https://github.com/obophenotype/cell-ontology/issues/1930>)
AnnotationAssertion(rdfs:comment obo:CL_0000728 "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to secondary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004232.")
AnnotationAssertion(rdfs:label obo:CL_0000728 "obsolete secondary pigment cell")
AnnotationAssertion(owl:deprecated obo:CL_0000728 "true"^^xsd:boolean)

# Class: obo:CL_0000729 (obsolete tertiary pigment cell)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0000729 <https://github.com/obophenotype/cell-ontology/issues/1930>)
AnnotationAssertion(rdfs:comment obo:CL_0000729 "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to tertiary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004233.")
AnnotationAssertion(rdfs:label obo:CL_0000729 "obsolete tertiary pigment cell")
AnnotationAssertion(owl:deprecated obo:CL_0000729 "true"^^xsd:boolean)

# Class: obo:CL_0000730 (leading edge cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MA:ma") obo:IAO_0000115 obo:CL_0000730 "A cell at the front of a migrating epithelial sheet.")
AnnotationAssertion(rdfs:label obo:CL_0000730 "leading edge cell")
SubClassOf(obo:CL_0000730 obo:CL_0000066)

# Class: obo:CL_0000731 (urothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MA:ma") Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") obo:IAO_0000115 obo:CL_0000731 "A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000731 "FMA:84127")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000731 "urinary tract transitional epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0000731 "urothelial cell")
EquivalentClasses(obo:CL_0000731 ObjectIntersectionOf(obo:CL_0000244 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000365)))

# Class: obo:CL_0000732 (amoeboid cell)

AnnotationAssertion(rdfs:label obo:CL_0000732 "amoeboid cell")
SubClassOf(obo:CL_0000732 obo:CL_0000219)

# Class: obo:CL_0000733 (lymph gland plasmatocyte)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0000733 "A plasmatocyte that derives from the larval lymph gland.")
AnnotationAssertion(rdfs:label obo:CL_0000733 "lymph gland plasmatocyte")
SubClassOf(obo:CL_0000733 obo:CL_0000394)
SubClassOf(obo:CL_0000733 obo:CL_0000735)

# Class: obo:CL_0000734 (obsolete embryonic gland plasmatocyte)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000734 obo:CL_0011009)
AnnotationAssertion(rdfs:comment obo:CL_0000734 "Obsoleted as this is the same thing as 'embryonic plasmatocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0000734 "obsolete embryonic gland plasmatocyte")
AnnotationAssertion(owl:deprecated obo:CL_0000734 "true"^^xsd:boolean)

# Class: obo:CL_0000735 (lymph gland hemocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1242/dev.00702") obo:IAO_0000115 obo:CL_0000735 "A hemocyte that derives from the larval lymph gland.")
AnnotationAssertion(rdfs:label obo:CL_0000735 "lymph gland hemocyte")
SubClassOf(obo:CL_0000735 obo:CL_0000387)

# Class: obo:CL_0000736 (obsolete embryonic gland hemocyte)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0000736 obo:CL_0011008)
AnnotationAssertion(rdfs:comment obo:CL_0000736 "Obsoleted as this term probably resulted from a confusion. Hemocytes are either derived from the embryonic head mesoderm (\"embryonic hemocytes\") or from the larval lymph gland (\"lymph gland hemocytes\"), not from an \"embryonic gland\".")
AnnotationAssertion(rdfs:label obo:CL_0000736 "obsolete embryonic gland hemocyte")
AnnotationAssertion(owl:deprecated obo:CL_0000736 "true"^^xsd:boolean)

# Class: obo:CL_0000737 (striated muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000737 "Muscle cell which has as its direct parts myofilaments organized into sarcomeres.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000737 "BTO:0002916")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000737 "CALOHA:TS-2157")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000737 "FMA:86936")
AnnotationAssertion(rdfs:label obo:CL_0000737 "striated muscle cell")
EquivalentClasses(obo:CL_0000737 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001410)))
SubClassOf(obo:CL_0000737 obo:CL_0000187)
DisjointClasses(obo:CL_0000737 obo:CL_0008000)

# Class: obo:CL_0000738 (leukocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:978-0-323-05290-0") obo:IAO_0000115 obo:CL_0000738 "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000738 "BTO:0000751")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000738 "CALOHA:TS-0549")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000738 "FMA:62852")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000738 "MESH:D007962")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000738 "NCIT:C12529")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000738 "leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000738 "white blood cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000738 "immune cell")
AnnotationAssertion(rdfs:label obo:CL_0000738 "leukocyte")
EquivalentClasses(obo:CL_0000738 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001667)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000738 obo:CL_0000988)
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002405))
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037))

# Class: obo:CL_0000739 (obo:CL_0000739)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000739 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000739 obo:CL_0000043)
AnnotationAssertion(owl:deprecated obo:CL_0000739 "true"^^xsd:boolean)

# Class: obo:CL_0000740 (retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dph") obo:IAO_0000115 obo:CL_0000740 "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000740 "BTO:0001800")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000740 "FMA:67765")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000740 "MESH:D012165")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000740 "gangliocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000740 "ganglion cell of retina")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000740 "RGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000740 "RGCs")
AnnotationAssertion(rdfs:label obo:CL_0000740 "retinal ganglion cell")
SubClassOf(obo:CL_0000740 obo:CL_0000540)
SubClassOf(obo:CL_0000740 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000966))

# Class: obo:CL_0000741 (spinal accessory motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16267219") obo:IAO_0000115 obo:CL_0000741 "A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000741 "SACMN")
AnnotationAssertion(rdfs:label obo:CL_0000741 "spinal accessory motor neuron")
SubClassOf(obo:CL_0000741 obo:CL_0008039)

# Class: obo:CL_0000742 (periarticular chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15951842") obo:IAO_0000115 obo:CL_0000742 "A round chondrocyte that first differentiates in the late embryonic growth plate of bone.")
AnnotationAssertion(rdfs:label obo:CL_0000742 "periarticular chondrocyte")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000742 obo:CL_0000138)
SubClassOf(obo:CL_0000742 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010996))

# Class: obo:CL_0000743 (hypertrophic chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "PMID:15951842") Annotation(oboInOwl:hasDbXref "PMID:25321476") Annotation(oboInOwl:hasDbXref "PMID:35179487") obo:IAO_0000115 obo:CL_0000743 "A chondrocyte that is part of the hypertrophic cartilage zone. This cell is significantly enlarged and characterised by high expression of type X collagen (COL10A1) in both humans and mice. It actively coordinates endochondral ossification by mineralising the extracellular matrix, attracting blood vessels via angiogenic signalling, and mediating the transition from cartilage to bone - often by transdifferentiating into an osteoblast rather than undergoing apoptosis.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35179487") rdfs:comment obo:CL_0000743 "Despite historical descriptions as 'terminally differentiated,' hypertrophic chondrocytes survive and transdifferentiate into osteoblasts. Genetic lineage tracing shows that hypertrophic chondrocytes do not simply undergo apoptosis but cross the cartilage–bone boundary, dedifferentiate into skeletal stem/progenitor cells, and then redifferentiate into osteoblasts and osteocytes. Single-cell RNA-seq further indicates that these chondrocyte-derived SSPCs are a major source of trabecular osteoblasts and marrow adipocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000743 "hypertrophic chondrocyte")
EquivalentClasses(obo:CL_0000743 ObjectIntersectionOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008187)))
SubClassOf(obo:CL_0000743 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001958))
SubClassOf(obo:CL_0000743 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000005693))

# Class: obo:CL_0000744 (columnar chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15951842") obo:IAO_0000115 obo:CL_0000744 "A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate.")
AnnotationAssertion(rdfs:label obo:CL_0000744 "columnar chondrocyte")
SubClassOf(obo:CL_0000744 obo:CL_0000138)

# Class: obo:CL_0000745 (retina horizontal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0195088433") obo:IAO_0000115 obo:CL_0000745 "A neuron that laterally connects other neurons in the inner nuclear layer of the retina.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000745 "BTO:0004120")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000745 "horizontal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000745 "HC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000745 "HCs")
AnnotationAssertion(rdfs:label obo:CL_0000745 "retina horizontal cell")
SubClassOf(obo:CL_0000745 obo:CL_0000099)
SubClassOf(obo:CL_0000745 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0003902))

# Class: obo:CL_0000746 (cardiac muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mtg_cardiacconduct_nov11") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") Annotation(oboInOwl:hasDbXref "PMID:22426062") Annotation(oboInOwl:hasDbXref "PMID:4711263") obo:IAO_0000115 obo:CL_0000746 "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000746 "cardiocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000746 "BTO:0001539")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000746 "CALOHA:TS-0115")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000746 "FMA:14067")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000746 "MESH:D032383")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0048739") oboInOwl:hasExactSynonym obo:CL_0000746 "cardiac muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000746 "cardiac myocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000746 "cardiomyocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000746 "heart muscle cell")
AnnotationAssertion(rdfs:comment obo:CL_0000746 "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods.  The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein).  According to these refs, the cells participating in heart contraction in all cases are transversely striated.  Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.")
AnnotationAssertion(rdfs:label obo:CL_0000746 "cardiac muscle cell")
EquivalentClasses(obo:CL_0000746 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007100) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0060047)))
SubClassOf(obo:CL_0000746 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000513))

# Class: obo:CL_0000747 (cyanophore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000747 "A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000747 "blue chromatophore")
AnnotationAssertion(rdfs:label obo:CL_0000747 "cyanophore")
SubClassOf(obo:CL_0000747 obo:CL_0000147)
SubClassOf(obo:CL_0000747 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005005))

# Class: obo:CL_0000748 (retinal bipolar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000748 "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000748 "BC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000748 "BCs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "geo:GSE137537") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_0000748 "BPs")
AnnotationAssertion(rdfs:label obo:CL_0000748 "retinal bipolar neuron")
EquivalentClasses(obo:CL_0000748 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001791)))
SubClassOf(obo:CL_0000748 obo:CL_0009004)
SubClassOf(obo:CL_0000748 ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0061535 ObjectSomeValuesFrom(obo:BFO_0000050 obo:GO_0098976))))
SubClassOf(obo:CL_0000748 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0007601))

# Class: obo:CL_0000749 (ON-bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000749 "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors.")
AnnotationAssertion(rdfs:label obo:CL_0000749 "ON-bipolar cell")
SubClassOf(obo:CL_0000749 obo:CL_0000748)

# Class: obo:CL_0000750 (OFF-bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000750 "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolarize in response to light to dark transition.")
AnnotationAssertion(rdfs:label obo:CL_0000750 "OFF-bipolar cell")
SubClassOf(obo:CL_0000750 obo:CL_0000748)

# Class: obo:CL_0000751 (rod bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000751 "A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells.  These neurons depolarize in response to light.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38627529") obo:RO_0002175 obo:CL_0000751 obo:NCBITaxon_32443)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000751 "FMA:67750")
AnnotationAssertion(rdfs:label obo:CL_0000751 "rod bipolar cell")
SubClassOf(obo:CL_0000751 obo:CL_0000749)
SubClassOf(obo:CL_0000751 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008925))
SubClassOf(obo:CL_0000751 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008926))
SubClassOf(obo:CL_0000751 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000604))

# Class: obo:CL_0000752 (cone retinal bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000752 "A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer.")
AnnotationAssertion(rdfs:label obo:CL_0000752 "cone retinal bipolar cell")
EquivalentClasses(obo:CL_0000752 ObjectIntersectionOf(obo:CL_0000748 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573)))
SubClassOf(obo:CL_0000752 obo:CL_0000748)

# Class: obo:CL_0000753 (type 1 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000753 "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000753 "DB1 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000753 "type 1 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000753 obo:CL_0000748)
SubClassOf(obo:CL_0000753 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008922))
SubClassOf(obo:CL_0000753 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000754 (type 2 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") Annotation(oboInOwl:hasDbXref "PMID:27565351") obo:IAO_0000115 obo:CL_0000754 "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1 (Ghosh et al., 2004).  It can be differentiated from other retinal bipolar neurons by its expression of marker genes: Neto1, Lhx3 and Irx-6 (Shekhar, 2016).")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000754 "FMB cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000754 "type 2 cone bipolar cell (sensu Mus)")
EquivalentClasses(Annotation(oboInOwl:hasDbXref "PMID:27565351") obo:CL_0000754 ObjectIntersectionOf(obo:CL_0000748 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P50481) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q8R4I7) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q9ER75)))
SubClassOf(obo:CL_0000754 obo:CL_0000748)
SubClassOf(obo:CL_0000754 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008922))
SubClassOf(obo:CL_0000754 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000755 (type 3 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000755 "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000755 "DB2 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000755 "type 3 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000755 obo:CL_0000748)
SubClassOf(obo:CL_0000755 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008923))
SubClassOf(obo:CL_0000755 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))
SubClassOf(obo:CL_0000755 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000604))

# Class: obo:CL_0000756 (type 4 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000756 "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000756 "DB3 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000756 "type 4 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000756 obo:CL_0000748)
SubClassOf(obo:CL_0000756 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008923))
SubClassOf(obo:CL_0000756 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008924))
SubClassOf(obo:CL_0000756 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))
SubClassOf(obo:CL_0000756 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000604))

# Class: obo:CL_0000757 (type 5 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000757 "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000757 "DB4 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000757 "type 5 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000757 obo:CL_0000748)
SubClassOf(obo:CL_0000757 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008924))
SubClassOf(obo:CL_0000757 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000758 (type 6 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000758 "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000758 "DB5 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000758 "type 6 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000758 obo:CL_0000748)
SubClassOf(obo:CL_0000758 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008925))
SubClassOf(obo:CL_0000758 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000759 (type 7 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000759 "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000759 "IMB cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000759 "type 7 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000759 obo:CL_0000748)
SubClassOf(obo:CL_0000759 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008925))
SubClassOf(obo:CL_0000759 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000760 (type 8 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000760 "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000760 "DB6 cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000760 "type 8 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000760 obo:CL_0000748)
SubClassOf(obo:CL_0000760 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008925))
SubClassOf(obo:CL_0000760 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008926))
SubClassOf(obo:CL_0000760 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000761 (type 9 cone bipolar cell (sensu Mus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14689473") obo:IAO_0000115 obo:CL_0000761 "An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000761 "BB cone bipolar cell")
AnnotationAssertion(rdfs:label obo:CL_0000761 "type 9 cone bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0000761 obo:CL_0000748)
SubClassOf(obo:CL_0000761 ObjectSomeValuesFrom(obo:RO_0002102 obo:UBERON_0008926))
SubClassOf(obo:CL_0000761 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000573))

# Class: obo:CL_0000762 (nucleated thrombocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16360205") obo:IAO_0000115 obo:CL_0000762 "A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates.")
AnnotationAssertion(rdfs:comment obo:CL_0000762 "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals.")
AnnotationAssertion(rdfs:label obo:CL_0000762 "nucleated thrombocyte")
EquivalentClasses(obo:CL_0000762 ObjectIntersectionOf(obo:CL_0000763 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007596)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000762 obo:CL_0000763)
SubClassOf(obo:CL_0000762 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000828))

# Class: obo:CL_0000763 (myeloid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000763 "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000763 "BTO:0001441")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000763 "CALOHA:TS-0647")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000763 "MESH:D022423")
AnnotationAssertion(rdfs:label obo:CL_0000763 "myeloid cell")
EquivalentClasses(obo:CL_0000763 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000763 obo:CL_0000988)

# Class: obo:CL_0000764 (erythroid lineage cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000764 "A immature or mature cell in the lineage leading to and including erythrocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000764 "CALOHA:TS-0290")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000764 "FMA:62845")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000764 "FMA:83516")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000764 "erythropoietic cell")
AnnotationAssertion(rdfs:comment obo:CL_0000764 "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000764 "erythroid lineage cell")
SubClassOf(obo:CL_0000764 obo:CL_0000763)

# Class: obo:CL_0000765 (erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18174176") obo:IAO_0000115 obo:CL_0000765 "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000765 "BTO:0001571")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000765 "CALOHA:TS-0289")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000765 "FMA:83504")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000765 "MESH:D004900")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000765 "normoblast")
AnnotationAssertion(rdfs:label obo:CL_0000765 "erythroblast")
EquivalentClasses(obo:CL_0000765 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005634) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030218)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000765 obo:CL_0000764)
SubClassOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547))

# Class: obo:CL_0000766 (myeloid leukocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000766 "A cell of the monocyte, granulocyte, or mast cell lineage.")
AnnotationAssertion(rdfs:label obo:CL_0000766 "myeloid leukocyte")
EquivalentClasses(obo:CL_0000766 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000766 obo:CL_0000738)

# Class: obo:CL_0000767 (basophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "MESH:D001491") Annotation(oboInOwl:hasDbXref "PMCID:PMC2626675") Annotation(oboInOwl:hasDbXref "PMID:11927641") Annotation(oboInOwl:hasDbXref "PMID:19741522") Annotation(oboInOwl:hasDbXref "PMID:21236338") Annotation(oboInOwl:hasDbXref "PMID:9933081") obo:IAO_0000115 obo:CL_0000767 "Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000767 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000767 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000767 "BTO:0000129")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000767 "CALOHA:TS-0073")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000767 "FMA:62862")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000767 "basophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000767 "basophilic leukocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000767 "Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000767 "basophil")
EquivalentClasses(obo:CL_0000767 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001344) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001950) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000767 obo:CL_0000094)

# Class: obo:CL_0000768 (immature basophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000768 "Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000768 "immature basophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000768 "immature basophilic leukocyte")
AnnotationAssertion(rdfs:label obo:CL_0000768 "immature basophil")
EquivalentClasses(obo:CL_0000768 ObjectIntersectionOf(obo:CL_0000767 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000768 obo:CL_0000767)
SubClassOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000830))

# Class: obo:CL_0000769 (basophilic metamyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18466030") obo:IAO_0000115 obo:CL_0000769 "A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000769 "FMA:84198")
AnnotationAssertion(rdfs:label obo:CL_0000769 "basophilic metamyelocyte")
EquivalentClasses(obo:CL_0000769 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000769 obo:CL_0000768)
SubClassOf(obo:CL_0000769 obo:CL_0002192)
SubClassOf(obo:CL_0000769 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000614))

# Class: obo:CL_0000770 (band form basophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18466030") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000770 "A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil.")
AnnotationAssertion(rdfs:label obo:CL_0000770 "band form basophil")
EquivalentClasses(obo:CL_0000770 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000770 obo:CL_0000768)
SubClassOf(obo:CL_0000770 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000769))

# Class: obo:CL_0000771 (eosinophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMCID:PMC2626675") Annotation(oboInOwl:hasDbXref "PMID:10914487") Annotation(oboInOwl:hasDbXref "PMID:1662676") obo:IAO_0000115 obo:CL_0000771 "Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000771 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000771 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000771 "BTO:0000399")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000771 "CALOHA:TS-0279")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000771 "FMA:62861")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000771 "MESH:D004804")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000771 "eosinocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000771 "eosinophilic granulocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000771 "eosinophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000771 "eosinophilic leukocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000771 "Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.")
AnnotationAssertion(rdfs:label obo:CL_0000771 "eosinophil")
EquivalentClasses(obo:CL_0000771 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001254) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000771 obo:CL_0000094)

# Class: obo:CL_0000772 (immature eosinophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000772 "Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000772 "immature eosinocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000772 "immature eosinophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000772 "immature eosinophilic leukocyte")
AnnotationAssertion(rdfs:label obo:CL_0000772 "immature eosinophil")
EquivalentClasses(obo:CL_0000772 ObjectIntersectionOf(obo:CL_0000771 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000772 obo:CL_0000771)
SubClassOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000833))

# Class: obo:CL_0000773 (eosinophilic metamyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:19622087") obo:IAO_0000115 obo:CL_0000773 "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000773 "eosinophilic metamyelocyte")
EquivalentClasses(obo:CL_0000773 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000773 obo:CL_0000772)
SubClassOf(obo:CL_0000773 obo:CL_0002192)
SubClassOf(obo:CL_0000773 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000612))

# Class: obo:CL_0000774 (band form eosinophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:19622087") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000774 "A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil.")
AnnotationAssertion(rdfs:label obo:CL_0000774 "band form eosinophil")
EquivalentClasses(obo:CL_0000774 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000774 obo:CL_0000772)
SubClassOf(obo:CL_0000774 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000773))

# Class: obo:CL_0000775 (neutrophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000775 "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "PMN")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "poly")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "polymorphonuclear leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "polymorphonuclear leukocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "polymorphonuclear neutrophil")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "polynuclear neutrophilic leucocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000775 "polynuclear neutrophilic leukocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000775 "BTO:0000130")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000775 "CALOHA:TS-0688")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000775 "FMA:62860")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000775 "MESH:D009504")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophil leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophil leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophilic leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophilic leukocyte")
AnnotationAssertion(rdfs:label obo:CL_0000775 "neutrophil")
EquivalentClasses(obo:CL_0000775 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001479) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000775 obo:CL_0000094)

# Class: obo:CL_0000776 (immature neutrophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000776 "Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immatuer neutrophilic leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrophil leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrophil leukocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrophilic leucocyte")
AnnotationAssertion(rdfs:label obo:CL_0000776 "immature neutrophil")
EquivalentClasses(obo:CL_0000776 ObjectIntersectionOf(obo:CL_0000775 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000776 obo:CL_0000775)
SubClassOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000564))

# Class: obo:CL_0000777 (mesangial phagocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation(oboInOwl:hasDbXref "ISBN:3540536663") Annotation(oboInOwl:hasDbXref "PMID:1600140") Annotation(oboInOwl:hasDbXref "PMID:16146841") obo:IAO_0000115 obo:CL_0000777 "A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000777 "mesangial cell")
AnnotationAssertion(rdfs:label obo:CL_0000777 "mesangial phagocyte")
EquivalentClasses(obo:CL_0000777 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0002320) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048771)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000777 obo:CL_0000864)

# Class: obo:CL_0000778 (mononuclear osteoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12713016") Annotation(oboInOwl:hasDbXref "PMID:15055519") Annotation(oboInOwl:hasDbXref "PMID:17380158") Annotation(oboInOwl:hasDbXref "PMID:9415452") obo:IAO_0000115 obo:CL_0000778 "A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts.")
AnnotationAssertion(rdfs:comment obo:CL_0000778 "Morphology: mononuclear, highly vesicular.")
AnnotationAssertion(rdfs:label obo:CL_0000778 "mononuclear osteoclast")
EquivalentClasses(obo:CL_0000778 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000778 obo:CL_0000092)

# Class: obo:CL_0000779 (multinuclear osteoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:12713016") Annotation(oboInOwl:hasDbXref "PMID:29379067") Annotation(oboInOwl:hasDbXref "PMID:38903088") Annotation(oboInOwl:hasDbXref "PMID:9415452") obo:IAO_0000115 obo:CL_0000779 "A specialized multinuclear osteoclast, forming a syncytium through the fusion of mononuclear precursor cells, associated with the absorption and removal of bone.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000779 "multinucleated osteoclast")
AnnotationAssertion(rdfs:comment obo:CL_0000779 "Morphology: multinucleated, highly vesicular.")
AnnotationAssertion(rdfs:label obo:CL_0000779 "multinuclear osteoclast")
EquivalentClasses(obo:CL_0000779 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000779 obo:CL_0000092)
SubClassOf(obo:CL_0000779 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000778))
SubClassOf(obo:CL_0000779 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0000768))

# Class: obo:CL_0000780 (multinuclear odontoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:9415452") obo:IAO_0000115 obo:CL_0000780 "A specialized multinuclear osteoclast associated with the absorption and removal of cementum.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000780 "multinucleated odontoclast")
AnnotationAssertion(rdfs:comment obo:CL_0000780 "Morphology: multinucleated, highly vesicular; location: roots of deciduous (milk) teeth.")
AnnotationAssertion(rdfs:label obo:CL_0000780 "multinuclear odontoclast")
EquivalentClasses(obo:CL_0000780 ObjectIntersectionOf(obo:CL_0000588 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000780 obo:CL_0000588)
SubClassOf(obo:CL_0000780 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000781))

# Class: obo:CL_0000781 (mononuclear odontoclast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:9415452") obo:IAO_0000115 obo:CL_0000781 "A specialized mononuclear osteoclast associated with the absorption and removal of cementum.")
AnnotationAssertion(rdfs:comment obo:CL_0000781 "Morphology: Mononuclear, highly vesicular; location: roots of deciduous (milk) teeth.")
AnnotationAssertion(rdfs:label obo:CL_0000781 "mononuclear odontoclast")
EquivalentClasses(obo:CL_0000781 ObjectIntersectionOf(obo:CL_0000588 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000781 obo:CL_0000588)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000781 obo:CL_0000778)

# Class: obo:CL_0000782 (myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:10449155") Annotation(oboInOwl:hasDbXref "PMID:17332250") Annotation(oboInOwl:hasDbXref "PMID:9521319") obo:IAO_0000115 obo:CL_0000782 "A dendritic cell of the myeloid lineage.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000782 "interdigitating cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000782 "veiled cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000782 "BTO:0004721")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000782 "CD11c+CD123- DC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000782 "mDC")
AnnotationAssertion(rdfs:comment obo:CL_0000782 "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).")
AnnotationAssertion(rdfs:label obo:CL_0000782 "myeloid dendritic cell")
EquivalentClasses(obo:CL_0000782 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000763)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000782 obo:CL_0000990)

# Class: obo:CL_0000783 (multinucleated phagocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000783 "A phagocyte formed by the fusion of mononuclear phagocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000783 "multinucleated phagocyte")
EquivalentClasses(obo:CL_0000783 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000783 obo:CL_0000518)

# Class: obo:CL_0000784 (plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMCID:PMC2118448") Annotation(oboInOwl:hasDbXref "PMCID:PMC538703") Annotation(oboInOwl:hasDbXref "PMID:15549123") Annotation(oboInOwl:hasDbXref "PMID:17332250") Annotation(oboInOwl:hasDbXref "PMID:17850486") Annotation(oboInOwl:hasDbXref "PMID:20304825") obo:IAO_0000115 obo:CL_0000784 "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000784 "BTO:0004625")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "DC2")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "IPC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "T-associated plasma cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "interferon-producing cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "lymphoid dendritic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "pDC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "plasmacytoid T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "plasmacytoid monocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "type 2 DC")
AnnotationAssertion(rdfs:label obo:CL_0000784 "plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000784 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032606)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000784 obo:CL_0000451)
SubClassOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037))

# Class: obo:CL_0000785 (mature B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000785 "A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000785 "mature B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000785 "mature B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000785 "mature B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000785 "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000785 "mature B cell")
EquivalentClasses(obo:CL_0000785 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042113) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002335)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000785 obo:CL_0001201)
SubClassOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818))
DisjointClasses(obo:CL_0000785 obo:CL_0000816)
DisjointClasses(obo:CL_0000785 obo:CL_0000817)
DisjointClasses(obo:CL_0000785 obo:CL_0000818)

# Class: obo:CL_0000786 (plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:19447676") Annotation(oboInOwl:hasDbXref "PMID:20081059") Annotation(oboInOwl:hasDbXref "PMID:20839338") Annotation(oboInOwl:hasDbXref "PMID:20951740") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Plasma_cell") obo:IAO_0000115 obo:CL_0000786 "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000786 "BTO:0000392")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000786 "FMA:70574")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000786 "MESH:D010950")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000786 "plasma B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000786 "plasma B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000786 "plasmacyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000786 "plasmocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000786 "effector B cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000786 "effector B-cell")
AnnotationAssertion(rdfs:comment obo:CL_0000786 "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000786 "plasma cell")
EquivalentClasses(obo:CL_0000786 ObjectIntersectionOf(obo:CL_0000946 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017508) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005794) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019814) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001935)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000786 obo:CL_0000946)
SubClassOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980))

# Class: obo:CL_0000787 (memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:20081059") Annotation(oboInOwl:hasDbXref "PMID:20839338") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Memory_B_cell") obo:IAO_0000115 obo:CL_0000787 "A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000787 "memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000787 "memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000787 "memory B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000787 "Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000787 "memory B cell")
EquivalentClasses(obo:CL_0000787 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002344)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000787 obo:CL_0000785)

# Class: obo:CL_0000788 (naive B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") Annotation(oboInOwl:hasDbXref "PMID:19447676") Annotation(oboInOwl:hasDbXref "PMID:20081059") Annotation(oboInOwl:hasDbXref "PMID:20839338") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000788 "A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000788 "naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000788 "naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000788 "naive B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000788 "This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000788 "naive B cell")
EquivalentClasses(obo:CL_0000788 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0002344) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000788 obo:CL_0000785)
SubClassOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818))

# Class: obo:CL_0000789 (alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000789 "A T cell that expresses an alpha-beta T cell receptor complex.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000789 "alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000789 "alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000789 "alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000789 "alpha-beta T cell")
EquivalentClasses(obo:CL_0000789 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000789 obo:CL_0000084)
DisjointClasses(obo:CL_0000789 obo:CL_0000798)

# Class: obo:CL_0000790 (immature alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000790 "An alpha-beta T cell that has an immature phenotype and has not completed T cell selection.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000790 "immature alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000790 "immature alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000790 "immature alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000790 "immature alpha-beta T cell")
EquivalentClasses(obo:CL_0000790 ObjectIntersectionOf(obo:CL_0000789 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000790 obo:CL_0000789)

# Class: obo:CL_0000791 (mature alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000791 "A alpha-beta T cell that has a mature phenotype.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000791 "mature alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000791 "mature alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000791 "mature alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000791 "mature alpha-beta T cell")
EquivalentClasses(obo:CL_0000791 ObjectIntersectionOf(obo:CL_0000789 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000791 obo:CL_0000789)
SubClassOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000790))

# Class: obo:CL_0000792 (CD4-positive, CD25-positive, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:19464985") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000792 "A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000792 "Treg")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000792 "suppressor T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000792 "suppressor T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000792 "suppressor T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000792 "suppressor T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000792 "CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000792 "CD4-positive, CD25-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000792 "CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000792 "This cell type is compatible with the HIPC Lyoplate markers for 'Treg'.  The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype.")
AnnotationAssertion(rdfs:label obo:CL_0000792 "CD4-positive, CD25-positive, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0000792 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001869)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000792 obo:CL_0000624)

# Class: obo:CL_0000793 (CD4-positive, alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000793 "A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000793 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000793 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0000793 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000793 obo:CL_0000624)
SubClassOf(obo:CL_0000793 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000810))

# Class: obo:CL_0000794 (CD8-positive, alpha-beta cytotoxic T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000794 "A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "cytotoxic T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "cytotoxic T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "cytotoxic T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "cytotoxic T-lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "killer T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "killer T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "killer T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000794 "killer T-lymphocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000794 "CALOHA:TS-0190")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000794 "CD8-positive, alpha-beta cytotoxic T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000794 "CD8-positive, alpha-beta cytotoxic T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000794 "CD8-positive, alpha-beta cytotoxic T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000794 "Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.")
AnnotationAssertion(rdfs:label obo:CL_0000794 "CD8-positive, alpha-beta cytotoxic T cell")
EquivalentClasses(obo:CL_0000794 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003466) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003499) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0033380) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000794 obo:CL_0000625)
SubClassOf(obo:CL_0000794 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906))

# Class: obo:CL_0000795 (CD8-positive, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000795 "A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000795 "suppressor T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000795 "suppressor T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000795 "suppressor T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000795 "suppressor T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8+ T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8+ regulatory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha-beta Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000795 "CD8-positive, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0000795 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000795 obo:CL_0000625)

# Class: obo:CL_0000796 (CD8-alpha-beta-positive, alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000796 "A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000796 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000796 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000796 "CD8-positive, alpha-beta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000796 "CD8-positive, alpha-beta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000796 "CD8-positive, alpha-beta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000796 "CD8-alpha-beta-positive, alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0000796 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000796 obo:CL_0000797)

# Class: obo:CL_0000797 (alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000797 "A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000797 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000797 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000797 "alpha-beta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000797 "alpha-beta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000797 "alpha-beta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000797 "alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0000797 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000797 obo:CL_0000791)

# Class: obo:CL_0000798 (gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000798 "A T cell that expresses a gamma-delta T cell receptor complex.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000798 "gamma-delta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000798 "gamma-delta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000798 "gamma-delta T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000798 "gammadelta T cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000798 "gd T cell")
AnnotationAssertion(rdfs:comment obo:CL_0000798 "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways.")
AnnotationAssertion(rdfs:label obo:CL_0000798 "gamma-delta T cell")
EquivalentClasses(obo:CL_0000798 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042106)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000798 obo:CL_0000084)

# Class: obo:CL_0000799 (immature gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000799 "A gamma-delta T cell that has an immature phenotype.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000799 "immature gamma-delta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000799 "immature gamma-delta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000799 "immature gamma-delta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000799 "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways.")
AnnotationAssertion(rdfs:label obo:CL_0000799 "immature gamma-delta T cell")
EquivalentClasses(obo:CL_0000799 ObjectIntersectionOf(obo:CL_0000798 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0042492) ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000799 obo:CL_0000798)
SubClassOf(obo:CL_0000799 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000807))

# Class: obo:CL_0000800 (mature gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000800 "A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000800 "mature gamma-delta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000800 "mature gamma-delta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000800 "mature gamma-delta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000800 "mature gamma-delta T cell")
EquivalentClasses(obo:CL_0000800 ObjectIntersectionOf(obo:CL_0000798 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000800 obo:CL_0000798)
SubClassOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000799))

# Class: obo:CL_0000801 (gamma-delta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000801 "A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000801 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000801 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000801 "gamma-delta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000801 "gamma-delta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000801 "gamma-delta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000801 "gamma-delta intraepithelial T cell")
EquivalentClasses(obo:CL_0000801 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000801 obo:CL_0000800)

# Class: obo:CL_0000802 (CD8-alpha alpha positive, gamma-delta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000802 "A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000802 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000802 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000802 "CD8-positive, gamma-delta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000802 "CD8-positive, gamma-delta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000802 "CD8-positive, gamma-delta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000802 "CD8-alpha alpha positive, gamma-delta intraepithelial T cell")
EquivalentClasses(obo:CL_0000802 ObjectIntersectionOf(obo:CL_0000801 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000802 obo:CL_0000801)

# Class: obo:CL_0000803 (CD4-negative CD8-negative gamma-delta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000803 "A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000803 "IEL")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000803 "intraepithelial lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000803 "CD4-positive, gamma-delta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000803 "CD4-positive, gamma-delta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000803 "CD4-positive, gamma-delta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000803 "CD4-negative CD8-negative gamma-delta intraepithelial T cell")
EquivalentClasses(obo:CL_0000803 ObjectIntersectionOf(obo:CL_0000801 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000803 obo:CL_0000801)

# Class: obo:CL_0000804 (obo:CL_0000804)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000804 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000804 obo:CL_0000084)
AnnotationAssertion(owl:deprecated obo:CL_0000804 "true"^^xsd:boolean)

# Class: obo:CL_0000805 (immature single positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000805 "A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "ISP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "T.ISP.th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "immature single positive T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "immature single positive T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "immature single positive T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000805 "Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages.")
AnnotationAssertion(rdfs:label obo:CL_0000805 "immature single positive thymocyte")
EquivalentClasses(obo:CL_0000805 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0043384) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000805 obo:CL_0000893)
SubClassOf(obo:CL_0000805 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000808))

# Class: obo:CL_0000806 (DN2 thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000806 "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "DN2 alpha-beta immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "DN2 alpha-beta immature T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "DN2 alpha-beta immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "DN2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "DN2 immature T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "TN2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "TN2 thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "double negative 2")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000806 "preT.DN2.Th")
AnnotationAssertion(rdfs:comment obo:CL_0000806 "Note that this type of thymocyte is at the earliest stage of T cell receptor rearrangement of the beta, gamma, and delta T cell receptor chains. Also, there is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0000806 "DN2 thymocyte")
EquivalentClasses(obo:CL_0000806 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(obo:CL_0000806 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894))

# Class: obo:CL_0000807 (DN3 thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000807 "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000807 "early cortical thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "DN3 alpha-beta immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "DN3 alpha-beta immature T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "DN3 alpha-beta immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "DN3 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "DN3 immature T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "TN3 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "TN3 thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "double negative 3")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000807 "preT.DN3.Th")
AnnotationAssertion(rdfs:comment obo:CL_0000807 "There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0000807 "DN3 thymocyte")
EquivalentClasses(obo:CL_0000807 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0043384) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(obo:CL_0000807 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000806))

# Class: obo:CL_0000808 (DN4 thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000808 "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000808 "early cortical thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "DN4 alpha-beta immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "DN4 alpha-beta immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "DN4 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "DN4 immature T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "DN4 immature T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "T.DN4.th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000808 "double negative 4")
AnnotationAssertion(rdfs:comment obo:CL_0000808 "Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0000808 "DN4 thymocyte")
EquivalentClasses(obo:CL_0000808 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0043384)))
SubClassOf(obo:CL_0000808 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000807))

# Class: obo:CL_0000809 (double-positive, alpha-beta thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000809 "A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000809 "late cortical thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000809 "DP cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000809 "DP thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000809 "double-positive, alpha-beta immature T lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000809 "Thymocytes of this stage are undergoing positive and negative selection.")
AnnotationAssertion(rdfs:label obo:CL_0000809 "double-positive, alpha-beta thymocyte")
EquivalentClasses(obo:CL_0000809 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000809 obo:CL_0000790)
SubClassOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000805))

# Class: obo:CL_0000810 (CD4-positive, alpha-beta thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000810 "An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "CD4-positive, alpha-beta immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "CD4-positive, alpha-beta immature T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "CD4-positive, alpha-beta immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "SP CD4 cell")
AnnotationAssertion(rdfs:label obo:CL_0000810 "CD4-positive, alpha-beta thymocyte")
EquivalentClasses(obo:CL_0000810 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000810 obo:CL_0000790)
SubClassOf(obo:CL_0000810 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))

# Class: obo:CL_0000811 (CD8-positive, alpha-beta thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000811 "An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000811 "CD8-positive, alpha-beta immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000811 "CD8-positive, alpha-beta immature T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000811 "CD8-positive, alpha-beta immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000811 "SP CD8 cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000811 "CD8-positive, alpha-beta immature T cell")
AnnotationAssertion(rdfs:label obo:CL_0000811 "CD8-positive, alpha-beta thymocyte")
EquivalentClasses(obo:CL_0000811 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000811 obo:CL_0000790)
SubClassOf(obo:CL_0000811 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))

# Class: obo:CL_0000812 (obo:CL_0000812)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000812 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000812 obo:CL_0000084)
AnnotationAssertion(owl:deprecated obo:CL_0000812 "true"^^xsd:boolean)

# Class: obo:CL_0000813 (memory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000813 "A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000813 "BTO:0003435")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000813 "memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000813 "memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000813 "memory T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000813 "memory T cell")
EquivalentClasses(obo:CL_0000813 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001603) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002286) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000813 obo:CL_0002419)
DisjointClasses(obo:CL_0000813 obo:CL_0000898)

# Class: obo:CL_0000814 (mature NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000814 "A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature NKT cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural killer T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural killer T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural killer T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural killer T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000814 "mature NK T cell")
EquivalentClasses(obo:CL_0000814 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032394) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000814 obo:CL_0000791)
SubClassOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000914))

# Class: obo:CL_0000815 (regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000815 "A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000815 "suppressor T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000815 "suppressor T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000815 "suppressor T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000815 "suppressor T-lymphocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000815 "BTO:0004520")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000815 "FMA:84070")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000815 "MESH:D050378")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000815 "Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000815 "regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000815 "regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000815 "regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000815 "This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta.")
AnnotationAssertion(rdfs:label obo:CL_0000815 "regulatory T cell")
EquivalentClasses(obo:CL_0000815 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000815 obo:CL_0002419)

# Class: obo:CL_0000816 (immature B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:20081059") Annotation(oboInOwl:hasDbXref "PMID:20839338") obo:IAO_0000115 obo:CL_0000816 "An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000816 "immature B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000816 "immature B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000816 "immature B-lymphocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:781735149") oboInOwl:hasExactSynonym obo:CL_0000816 "newly formed B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000816 "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000816 "immature B cell")
EquivalentClasses(obo:CL_0000816 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045190) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289)))
SubClassOf(obo:CL_0000816 obo:CL_0001201)
SubClassOf(obo:CL_0000816 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000954))

# Class: obo:CL_0000817 (precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000817 "A precursor B cell is a B cell with the phenotype CD10-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000817 "BTO:0001133")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000817 "CALOHA:TS-0819")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000817 "pre-B cell")
AnnotationAssertion(rdfs:label obo:CL_0000817 "precursor B cell")
EquivalentClasses(obo:CL_0000817 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000817 obo:CL_0001201)
DisjointClasses(obo:CL_0000817 obo:CL_0000826)

# Class: obo:CL_0000818 (transitional stage B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:12810111") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000818 "An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000818 "transitional B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000818 "transitional stage B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000818 "transitional stage B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000818 "transitional stage B-lymphocyte")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000818 "T1 B cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000818 "T2 B cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000818 "T3 B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000818 "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'.")
AnnotationAssertion(rdfs:label obo:CL_0000818 "transitional stage B cell")
EquivalentClasses(obo:CL_0000818 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0002335) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000818 obo:CL_0001201)
SubClassOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000816))

# Class: obo:CL_0000819 (B-1 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11861604") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "PMID:21220451") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/B-1_cell") obo:IAO_0000115 obo:CL_0000819 "A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B-1 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B-1 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B-1 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B-1 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 cell")
AnnotationAssertion(rdfs:comment obo:CL_0000819 "There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low.")
AnnotationAssertion(rdfs:label obo:CL_0000819 "B-1 B cell")
EquivalentClasses(obo:CL_0000819 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0071753)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000819 obo:CL_0000785)

# Class: obo:CL_0000820 (B-1a B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:11861604") obo:IAO_0000115 obo:CL_0000820 "A B-1 B cell that has the phenotype CD5-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B-1a B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B-1a B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B-1a B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B1a B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B1a B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B1a B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B1a B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "B1a cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "CD5(+) B1 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "CD5+ B1 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "CD5-positive B1 cell")
AnnotationAssertion(rdfs:label obo:CL_0000820 "B-1a B cell")
EquivalentClasses(obo:CL_0000820 ObjectIntersectionOf(obo:CL_0000819 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001839)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000820 obo:CL_0000819)

# Class: obo:CL_0000821 (B-1b B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:11861604") obo:IAO_0000115 obo:CL_0000821 "A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B-1b B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B-1b B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B-1b B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b cell")
AnnotationAssertion(rdfs:label obo:CL_0000821 "B-1b B cell")
EquivalentClasses(obo:CL_0000821 ObjectIntersectionOf(obo:CL_0000819 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000821 obo:CL_0000819)

# Class: obo:CL_0000822 (B-2 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:11861604") Annotation(oboInOwl:hasDbXref "PMID:20933013") obo:IAO_0000115 obo:CL_0000822 "A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B-2 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B-2 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B-2 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B2 B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B2 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B2 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B2 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000822 "B2 cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000822 "B-0 B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000822 "B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000822 "B-2 B cell")
EquivalentClasses(obo:CL_0000822 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000822 obo:CL_0000785)

# Class: obo:CL_0000823 (immature natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:12457618") obo:IAO_0000115 obo:CL_0000823 "A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR).")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000823 "immature NK cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12457618") oboInOwl:hasRelatedSynonym obo:CL_0000823 "p-NK")
AnnotationAssertion(rdfs:comment obo:CL_0000823 "In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules.")
AnnotationAssertion(rdfs:label obo:CL_0000823 "immature natural killer cell")
EquivalentClasses(obo:CL_0000823 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501)))
SubClassOf(obo:CL_0000823 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000937))
DisjointClasses(obo:CL_0000823 obo:CL_0000824)
DisjointClasses(obo:CL_0000823 obo:CL_0000937)

# Class: obo:CL_0000824 (mature natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:14685782") obo:IAO_0000115 obo:CL_0000824 "A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14685782") oboInOwl:hasBroadSynonym obo:CL_0000824 "LAK cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14685782") oboInOwl:hasBroadSynonym obo:CL_0000824 "lymphokine activated killer cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000824 "mature NK cell")
AnnotationAssertion(rdfs:label obo:CL_0000824 "mature natural killer cell")
EquivalentClasses(obo:CL_0000824 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001701)))
SubClassOf(obo:CL_0000824 obo:CL_0000623)
SubClassOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000823))

# Class: obo:CL_0000825 (pro-NK cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11532393") Annotation(oboInOwl:hasDbXref "PMID:12457618") Annotation(oboInOwl:hasDbXref "PMID:15032583") Annotation(oboInOwl:hasDbXref "PMID:15766674") obo:IAO_0000115 obo:CL_0000825 "A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12457618") Annotation(oboInOwl:hasDbXref "PMID:15032583") Annotation(oboInOwl:hasDbXref "PMID:15766674") oboInOwl:hasExactSynonym obo:CL_0000825 "NKP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000825 "natural killer cell progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000825 "pro-natural killer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11532393") oboInOwl:hasRelatedSynonym obo:CL_0000825 "null cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11532393") oboInOwl:hasRelatedSynonym obo:CL_0000825 "preNK cell")
AnnotationAssertion(rdfs:comment obo:CL_0000825 "Most markers only described for human pro NK cells.")
AnnotationAssertion(rdfs:label obo:CL_0000825 "pro-NK cell")
EquivalentClasses(obo:CL_0000825 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001381) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000825 obo:CL_0000838)
SubClassOf(obo:CL_0000825 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051))

# Class: obo:CL_0000826 (pro-B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:12633665") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0000826 "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17582343") oboInOwl:hasBroadSynonym obo:CL_0000826 "pre-pro B cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000826 "BTO:0003104")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "pro-B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "pro-B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "pro-B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "progenitor B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "progenitor B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "progenitor B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000826 "progenitor B-lymphocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11244048") oboInOwl:hasRelatedSynonym obo:CL_0000826 "pre-B cell (Philadelphia nomenclature)")
AnnotationAssertion(rdfs:comment obo:CL_0000826 "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000826 "pro-B cell")
EquivalentClasses(obo:CL_0000826 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001903) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000006611) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0033152)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000826 obo:CL_0000838)
SubClassOf(obo:CL_0000826 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051))

# Class: obo:CL_0000827 (pro-T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000827 "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000827 "pro-T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000827 "progenitor T cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000827 "DN1 cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000827 "DN1 thymocyte")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000827 "TN1 cell")
AnnotationAssertion(rdfs:label obo:CL_0000827 "pro-T cell")
EquivalentClasses(obo:CL_0000827 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000827 obo:CL_0000838)
SubClassOf(obo:CL_0000827 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051))

# Class: obo:CL_0000828 (thromboblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7758949") obo:IAO_0000115 obo:CL_0000828 "A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates.")
AnnotationAssertion(rdfs:comment obo:CL_0000828 "Note that this is a non-mammalian cell type.")
AnnotationAssertion(rdfs:label obo:CL_0000828 "thromboblast")
EquivalentClasses(obo:CL_0000828 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002574)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000828 obo:CL_0000839)
SubClassOf(obo:CL_0000828 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050))

# Class: obo:CL_0000829 (basophilic myeloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000829 "A myeloblast committed to the basophil lineage.")
AnnotationAssertion(rdfs:label obo:CL_0000829 "basophilic myeloblast")
EquivalentClasses(obo:CL_0000829 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000829 obo:CL_0000835)
SubClassOf(obo:CL_0000829 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000613))

# Class: obo:CL_0000830 (basophilic promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000830 "A promyelocyte committed to the basophil lineage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000830 "FMA:84208")
AnnotationAssertion(rdfs:label obo:CL_0000830 "basophilic promyelocyte")
EquivalentClasses(obo:CL_0000830 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000830 obo:CL_0000836)
SubClassOf(obo:CL_0000830 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000829))

# Class: obo:CL_0000831 (mast cell progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMCID:PMC1183570") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") Annotation(oboInOwl:hasDbXref "PMID:8629001") Annotation(oboInOwl:hasDbXref "PMID:9354811") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0000831 "A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000831 "MCP")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000831 "CFU-MC")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000831 "CFU-Mast")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000831 "colony forming unit mast cell")
AnnotationAssertion(rdfs:comment obo:CL_0000831 "MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa.")
AnnotationAssertion(rdfs:label obo:CL_0000831 "mast cell progenitor")
EquivalentClasses(obo:CL_0000831 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000005307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002980) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016401) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060374) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000009143) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000007431)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000831 obo:CL_0000839)
SubClassOf(obo:CL_0000831 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002028))

# Class: obo:CL_0000832 (eosinophilic myeloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000832 "A myeloblast committed to the eosinophil lineage.")
AnnotationAssertion(rdfs:label obo:CL_0000832 "eosinophilic myeloblast")
EquivalentClasses(obo:CL_0000832 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000832 obo:CL_0000835)
SubClassOf(obo:CL_0000832 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000611))

# Class: obo:CL_0000833 (eosinophilic promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000833 "A promyelocyte committed to the eosinophil lineage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000833 "FMA:84199")
AnnotationAssertion(rdfs:label obo:CL_0000833 "eosinophilic promyelocyte")
EquivalentClasses(obo:CL_0000833 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000833 obo:CL_0000836)
SubClassOf(obo:CL_0000833 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000832))

# Class: obo:CL_0000834 (neutrophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000834 "A progenitor cell of the neutrophil lineage.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000834 "neutrophil stem cell")
AnnotationAssertion(rdfs:label obo:CL_0000834 "neutrophil progenitor cell")
EquivalentClasses(obo:CL_0000834 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000834 obo:CL_0002191)
SubClassOf(obo:CL_0000834 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557))

# Class: obo:CL_0000835 (myeloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Myeloblast") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000835 "The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000835 "BTO:0000187")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000835 "FMA:83524")
AnnotationAssertion(rdfs:label obo:CL_0000835 "myeloblast")
EquivalentClasses(obo:CL_0000835 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000791) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0042582) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000835 obo:CL_0002191)
SubClassOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557))

# Class: obo:CL_0000836 (promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000836 "A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000836 "CALOHA:TS-0825")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000836 "FMA:83530")
AnnotationAssertion(rdfs:label obo:CL_0000836 "promyelocyte")
EquivalentClasses(obo:CL_0000836 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005730) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892)))
SubClassOf(obo:CL_0000836 obo:CL_0002191)
SubClassOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000835))

# Class: obo:CL_0000837 (hematopoietic multipotent progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0000837 "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000837 "BTO:0000725")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000837 "CALOHA:TS-0448")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000837 "MPP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000837 "hemopoietic progenitor cell")
AnnotationAssertion(rdfs:comment obo:CL_0000837 "Markers differ between mouse and human.")
AnnotationAssertion(rdfs:label obo:CL_0000837 "hematopoietic multipotent progenitor cell")
EquivalentClasses(obo:CL_0000837 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000837 obo:CL_0000988)
SubClassOf(obo:CL_0000837 obo:CL_0008001)
SubClassOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037))
DisjointClasses(obo:CL_0000837 obo:CL_0002032)

# Class: obo:CL_0000838 (lymphoid lineage restricted progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000838 "A progenitor cell restricted to the lymphoid lineage.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000838 "lymphoid progenitor cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000838 "BTO:0004731")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000838 "CALOHA:TS-2025")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000838 "FMA:70338")
AnnotationAssertion(rdfs:comment obo:CL_0000838 "Note that this is a class of cell types, not an identified single cell type.")
AnnotationAssertion(rdfs:label obo:CL_0000838 "lymphoid lineage restricted progenitor cell")
EquivalentClasses(obo:CL_0000838 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000838 obo:CL_0002031)
DisjointClasses(obo:CL_0000838 obo:CL_0000839)

# Class: obo:CL_0000839 (myeloid lineage restricted progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0000839 "A progenitor cell restricted to the myeloid lineage.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000839 "myeloid progenitor cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000839 "BTO:0004730")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000839 "CALOHA:TS-2099")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000839 "FMA:70339")
AnnotationAssertion(rdfs:comment obo:CL_0000839 "Note that this is a class of cell types, not an identified single cell type.")
AnnotationAssertion(rdfs:label obo:CL_0000839 "myeloid lineage restricted progenitor cell")
EquivalentClasses(obo:CL_0000839 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030099)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000839 obo:CL_0002031)

# Class: obo:CL_0000840 (immature conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9521319") obo:IAO_0000115 obo:CL_0000840 "An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low.")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000840 "immature myeloid dendritic cell")
AnnotationAssertion(rdfs:label obo:CL_0000840 "immature conventional dendritic cell")
EquivalentClasses(obo:CL_0000840 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000840 obo:CL_0000990)
SubClassOf(obo:CL_0000840 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029))

# Class: obo:CL_0000841 (mature conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9521319") obo:IAO_0000115 obo:CL_0000841 "A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") oboInOwl:hasBroadSynonym obo:CL_0000841 "mature dendritic cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000841 "FMA:83038")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000841 "mature myeloid dendritic cell")
AnnotationAssertion(rdfs:label obo:CL_0000841 "mature conventional dendritic cell")
EquivalentClasses(obo:CL_0000841 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000841 obo:CL_0000990)
SubClassOf(obo:CL_0000841 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000840))

# Class: obo:CL_0000842 (mononuclear leukocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000842 "A leukocyte with a single non-segmented nucleus in the mature form.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000842 "BTO:0000878")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000842 "CALOHA:TS-0768")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000842 "FMA:86713")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000842 "mononuclear cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000842 "peripheral blood mononuclear cell")
AnnotationAssertion(rdfs:label obo:CL_0000842 "mononuclear leukocyte")
EquivalentClasses(obo:CL_0000842 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000842 obo:CL_0000738)

# Class: obo:CL_0000843 (follicular B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMCID:PMC2193793") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Follicular_B_Cells") obo:IAO_0000115 obo:CL_0000843 "A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "Fo B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "Fo B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "follicular B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "follicular B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "follicular B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000843 "Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000843 "follicular B cell")
EquivalentClasses(obo:CL_0000843 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000843 obo:CL_0000785)

# Class: obo:CL_0000844 (germinal center B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:19447676") Annotation(oboInOwl:hasDbXref "PMID:20933013") obo:IAO_0000115 obo:CL_0000844 "A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "GC B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "GC B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "GC B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "GC B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "germinal center B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "germinal center B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "germinal center B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000844 "Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000844 "germinal center B cell")
EquivalentClasses(obo:CL_0000844 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010754) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000844 obo:CL_0000785)
SubClassOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000843))

# Class: obo:CL_0000845 (marginal zone B cell of spleen)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:10933592") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Marginal-zone_B_cell") obo:IAO_0000115 obo:CL_0000845 "A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "MZ B cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "MZ B lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "MZ B-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "MZ B-lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "marginal zone B cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "marginal zone B lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "marginal zone B-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000845 "marginal zone B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000845 "B cell of marginal zone of spleen")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000845 "marginal zone of spleen B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000845 "MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000845 "marginal zone B cell of spleen")
EquivalentClasses(obo:CL_0000845 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0071753)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000845 obo:CL_0000785)

# Class: obo:CL_0000846 (vestibular dark cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11223304") obo:IAO_0000115 obo:CL_0000846 "An epithelial cell of the vestibular sensory organ that is characterized by intense enzymatic activities and numerous basal membrane infoldings.")
AnnotationAssertion(rdfs:label obo:CL_0000846 "vestibular dark cell")
SubClassOf(obo:CL_0000846 obo:CL_0000066)

# Class: obo:CL_0000847 (ciliated olfactory receptor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16841163") obo:IAO_0000115 obo:CL_0000847 "An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000847 "ciliated olfactory sensory neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000847 "ciliated sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0000847 "ciliated olfactory receptor neuron")
EquivalentClasses(obo:CL_0000847 ObjectIntersectionOf(obo:CL_0000207 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929)))

# Class: obo:CL_0000848 (microvillous olfactory receptor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16841163") obo:IAO_0000115 obo:CL_0000848 "An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000848 "microvillous olfactory sensory neuron")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000848 "microvillous sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0000848 "microvillous olfactory receptor neuron")
SubClassOf(obo:CL_0000848 obo:CL_0000207)

# Class: obo:CL_0000849 (crypt olfactory receptor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16841163") obo:IAO_0000115 obo:CL_0000849 "An olfactory receptor cell with short cilia growing in an invagination bordered by microvilli.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000849 "crypt cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000849 "crypt olfactory sensory neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000849 "crypt sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0000849 "crypt olfactory receptor neuron")
SubClassOf(obo:CL_0000849 obo:CL_0000207)

# Class: obo:CL_0000850 (serotonergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000850 "A neuron that releases serotonin as a neurotransmitter.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000850 "MESH:D059326")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000850 "WBbt:0006837")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000850 "5-HT neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000850 "5-hydroxytryptamine neuron")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000850 "serotinergic neuron")
AnnotationAssertion(rdfs:label obo:CL_0000850 "serotonergic neuron")
EquivalentClasses(obo:CL_0000850 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060096)))
SubClassOf(obo:CL_0000850 obo:CL_0000540)

# Class: obo:CL_0000851 (neuromast mantle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0125296509") obo:IAO_0000115 obo:CL_0000851 "Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded.")
AnnotationAssertion(rdfs:label obo:CL_0000851 "neuromast mantle cell")
SubClassOf(obo:CL_0000851 obo:CL_0000151)
SubClassOf(obo:CL_0000851 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008904))
DisjointClasses(obo:CL_0000851 obo:CL_0000855)

# Class: obo:CL_0000852 (neuromast supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0125296509") obo:IAO_0000115 obo:CL_0000852 "Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000852 "neuromast support cell")
AnnotationAssertion(rdfs:label obo:CL_0000852 "neuromast supporting cell")
SubClassOf(obo:CL_0000852 obo:CL_0000630)
SubClassOf(obo:CL_0000852 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008904))
DisjointClasses(obo:CL_0000852 obo:CL_0000855)

# Class: obo:CL_0000853 (olfactory epithelial supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000853 "Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000853 "FMA:62302")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000853 "olfactory epithelial support cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000853 "olfactory sustentacular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000853 "supporting cell of olfactory epithelium")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000853 "sustentaculocyte of olfactory epithelium")
AnnotationAssertion(rdfs:label obo:CL_0000853 "olfactory epithelial supporting cell")
EquivalentClasses(obo:CL_0000853 ObjectIntersectionOf(obo:CL_0000630 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
SubClassOf(obo:CL_0000853 obo:CL_0000630)
SubClassOf(obo:CL_0000853 obo:CL_0002167)

# Class: obo:CL_0000854 (interneuromast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000854 "Interneuromast cell is a neuroectodermal cell deposited by the migrating lateral line primordium between the neuromasts. Interneuromast cells proliferate and migrate to form additional neuromasts.")
AnnotationAssertion(rdfs:label obo:CL_0000854 "interneuromast cell")
SubClassOf(obo:CL_0000854 obo:CL_0000133)
SubClassOf(obo:CL_0000854 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000032))

# Class: obo:CL_0000855 (sensory hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000855 "Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000855 "hair cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000855 "BTO:0004744")
AnnotationAssertion(rdfs:label obo:CL_0000855 "sensory hair cell")
SubClassOf(obo:CL_0000855 obo:CL_0000199)

# Class: obo:CL_0000856 (neuromast hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000856 "Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.")
AnnotationAssertion(rdfs:label obo:CL_0000856 "neuromast hair cell")
EquivalentClasses(obo:CL_0000856 ObjectIntersectionOf(obo:CL_0000855 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008904)))
SubClassOf(obo:CL_0000856 obo:CL_0000855)

# Class: obo:CL_0000857 (slow muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000857 "A skeletal muscle myoblast that differentiates into slow muscle fibers.")
AnnotationAssertion(rdfs:label obo:CL_0000857 "slow muscle myoblast")
EquivalentClasses(obo:CL_0000857 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000189)))

# Class: obo:CL_0000858 (fast muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0000858 "A skeletal muscle myoblast that differentiates into fast muscle fibers.")
AnnotationAssertion(rdfs:label obo:CL_0000858 "fast muscle myoblast")
EquivalentClasses(obo:CL_0000858 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000190)))

# Class: obo:CL_0000859 (obo:CL_0000859)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0000859 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0000859 obo:CL_0000061)
AnnotationAssertion(owl:deprecated obo:CL_0000859 "true"^^xsd:boolean)

# Class: obo:CL_0000860 (classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16322748") Annotation(oboInOwl:hasDbXref "PMID:18303997") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:20870168") obo:IAO_0000115 obo:CL_0000860 "A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000860 "inflammatory monocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000860 "Markers: CCR2+CXCCR1<low> (human, mouse, rat).")
AnnotationAssertion(rdfs:label obo:CL_0000860 "classical monocyte")
EquivalentClasses(obo:CL_0000860 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002548) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006954) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001199)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000860 obo:CL_0000576)

# Class: obo:CL_0000861 (elicited macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771589") obo:IAO_0000115 obo:CL_0000861 "A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000861 "FMA:84643")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000861 "FMA:84645")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000861 "free macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000861 "wandering histiocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000861 "Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response).")
AnnotationAssertion(rdfs:label obo:CL_0000861 "elicited macrophage")
EquivalentClasses(obo:CL_0000861 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0006954) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000861 obo:CL_0000235)
SubClassOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000860))

# Class: obo:CL_0000862 (suppressor macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20402419") obo:IAO_0000115 obo:CL_0000862 "A macrophage that suppresses immune responses.")
AnnotationAssertion(rdfs:comment obo:CL_0000862 "Markers: May express: IL10, TGFbeta.")
AnnotationAssertion(rdfs:label obo:CL_0000862 "suppressor macrophage")
EquivalentClasses(obo:CL_0000862 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000862 obo:CL_0000861)

# Class: obo:CL_0000863 (M1 macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19132917") obo:IAO_0000115 obo:CL_0000863 "An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30861466") oboInOwl:hasExactSynonym obo:CL_0000863 "classically activated macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000863 "inflammatory macrophage")
AnnotationAssertion(rdfs:comment obo:CL_0000863 "Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response).")
AnnotationAssertion(rdfs:label obo:CL_0000863 "M1 macrophage")
EquivalentClasses(obo:CL_0000863 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032611) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042554) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045428)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000863 obo:CL_0000861)
SubClassOf(obo:CL_0000863 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0020017))

# Class: obo:CL_0000864 (tissue-resident macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19770654") obo:IAO_0000115 obo:CL_0000864 "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000864 "FMA:84642")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000864 "FMA:84644")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "fixed macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "resting histiocyte")
AnnotationAssertion(rdfs:label obo:CL_0000864 "tissue-resident macrophage")
EquivalentClasses(obo:CL_0000864 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000479)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000864 obo:CL_0000235)

# Class: obo:CL_0000865 (gastrointestinal tract (lamina propria) macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2825-0621") obo:IAO_0000115 obo:CL_0000865 "A gut-associated lymphoid tissue macrophage found in lamina propria of the gut.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000865 "gastrointestinal system (lamina propria) macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000865 "macrophage of gastrointestinal system (lamina propria)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000865 "macrophage of gastrointestinal tract (lamina propria)")
AnnotationAssertion(rdfs:label obo:CL_0000865 "gastrointestinal tract (lamina propria) macrophage")
EquivalentClasses(obo:CL_0000865 ObjectIntersectionOf(obo:CL_0000885 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004780)))

# Class: obo:CL_0000866 (thymic macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9048205") obo:IAO_0000115 obo:CL_0000866 "A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes.")
AnnotationAssertion(rdfs:comment obo:CL_0000866 "Role or process: immune, clearance of apoptotic thymocytes, antigen-presentation.")
AnnotationAssertion(rdfs:label obo:CL_0000866 "thymic macrophage")
EquivalentClasses(obo:CL_0000866 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000866 obo:CL_0000864)

# Class: obo:CL_0000867 (secondary lymphoid organ macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000867 "A tissue-resident macrophage found in a secondary lymphoid organ.")
AnnotationAssertion(rdfs:label obo:CL_0000867 "secondary lymphoid organ macrophage")
SubClassOf(obo:CL_0000867 obo:CL_0000864)

# Class: obo:CL_0000868 (lymph node macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11971865") obo:IAO_0000115 obo:CL_0000868 "A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000868 "MF.LN")
AnnotationAssertion(rdfs:comment obo:CL_0000868 "Marker was observed on rat cells.")
AnnotationAssertion(rdfs:label obo:CL_0000868 "lymph node macrophage")
EquivalentClasses(obo:CL_0000868 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000029) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001813)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000868 obo:CL_0000867)

# Class: obo:CL_0000869 (tonsillar macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16048540") obo:IAO_0000115 obo:CL_0000869 "A gut-associated lymphoid tissue macrophage found in tonsils.")
AnnotationAssertion(rdfs:label obo:CL_0000869 "tonsillar macrophage")
EquivalentClasses(obo:CL_0000869 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002372) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002395)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000869 obo:CL_0000884)

# Class: obo:CL_0000870 (Peyer's patch macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000870 "A gut-associated lymphoid tissue macrophage found in the Peyer's patches.")
AnnotationAssertion(rdfs:label obo:CL_0000870 "Peyer's patch macrophage")
EquivalentClasses(obo:CL_0000870 ObjectIntersectionOf(obo:CL_0000885 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001211)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000870 obo:CL_0000885)

# Class: obo:CL_0000871 (splenic macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771589") Annotation(oboInOwl:hasDbXref "PMID:16322748") obo:IAO_0000115 obo:CL_0000871 "A secondary lymphoid organ macrophage found in the spleen.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000871 "FMA:83026")
AnnotationAssertion(rdfs:comment obo:CL_0000871 "Role or process: immune, clearance of apoptotic and senescent cells.")
AnnotationAssertion(rdfs:label obo:CL_0000871 "splenic macrophage")
EquivalentClasses(obo:CL_0000871 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002106) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000871 obo:CL_0000867)

# Class: obo:CL_0000872 (splenic marginal zone macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16861066") obo:IAO_0000115 obo:CL_0000872 "A splenic macrophage found in the marginal zone of the spleen, involved in recognition and clearance of particulate material from the splenic circulation. Markers include F4/80-negative, MARCO-positive, SR-A-positive, SIGN-R1-positive, and Dectin2-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000872 "Markers: Mouse: F4/80-, MARCO+, SR-A+, SIGN-R1+, Dectin2+.")
AnnotationAssertion(rdfs:label obo:CL_0000872 "splenic marginal zone macrophage")
EquivalentClasses(obo:CL_0000872 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001806) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001884) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001885) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006172)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000872 obo:CL_0000871)

# Class: obo:CL_0000873 (splenic metallophillic macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20018690") obo:IAO_0000115 obo:CL_0000873 "A splenic macrophage found in the areas surrounding the white pulp of the spleen, adjacent to the marginal sinus. Markers include F4/80-negative, Dectin2-low, sialoadhesin-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000873 "Markers: Mouse: F4/80-, Dectin2-low, sialoadhesin+.")
AnnotationAssertion(rdfs:label obo:CL_0000873 "splenic metallophillic macrophage")
EquivalentClasses(obo:CL_0000873 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001959) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001806)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000873 obo:CL_0000871)

# Class: obo:CL_0000874 (splenic red pulp macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19644016") obo:IAO_0000115 obo:CL_0000874 "A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low.")
AnnotationAssertion(rdfs:comment obo:CL_0000874 "Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes.")
AnnotationAssertion(rdfs:label obo:CL_0000874 "splenic red pulp macrophage")
EquivalentClasses(obo:CL_0000874 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001250) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001806) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006955) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001931)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000874 obo:CL_0000871)

# Class: obo:CL_0000875 (non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16322748") Annotation(oboInOwl:hasDbXref "PMID:18303997") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:20870168") obo:IAO_0000115 obo:CL_0000875 "A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000875 "patrolling monocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000875 "resident monocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000875 "Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-.")
AnnotationAssertion(rdfs:label obo:CL_0000875 "non-classical monocyte")
EquivalentClasses(obo:CL_0000875 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000587) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031294) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030224) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001206)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000875 obo:CL_0000576)
SubClassOf(obo:CL_0000875 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002393))

# Class: obo:CL_0000876 (splenic white pulp macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11207597") obo:IAO_0000115 obo:CL_0000876 "A splenic macrophage found in the white pulp of the spleen. Markers include F4/80-negative, CD68-positive, and macrosialin-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000876 "Markers: Mouse: F4/80-, CD68+, macrosialin+.")
AnnotationAssertion(rdfs:label obo:CL_0000876 "splenic white pulp macrophage")
EquivalentClasses(obo:CL_0000876 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001959) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000876 obo:CL_0000871)

# Class: obo:CL_0000877 (splenic tingible body macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19631584") obo:IAO_0000115 obo:CL_0000877 "A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000877 "splenic tingible body macrophage")
EquivalentClasses(obo:CL_0000877 ObjectIntersectionOf(obo:CL_0000876 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001249) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000010329) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000877 obo:CL_0000876)

# Class: obo:CL_0000878 (central nervous system macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16322748") obo:IAO_0000115 obo:CL_0000878 "A tissue-resident macrophage found in the central nervous system.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000878 "CNS macrophage")
AnnotationAssertion(rdfs:label obo:CL_0000878 "central nervous system macrophage")
EquivalentClasses(obo:CL_0000878 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000878 obo:CL_0000864)

# Class: obo:CL_0000879 (meningeal macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11591794") Annotation(oboInOwl:hasDbXref "PMID:24078900") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000879 "A border associated macrophage that is part of a meninx. This macrophage type is elongated and amoeboid spindle-shaped with limited mobility. This macrophage is highly phagocytic, expresses scavenger receptors, has dynamic protrusions and extends its processes during inflammation.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural leptomeningeal macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28323268") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural meningeal macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "MM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "MnMΦ")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "sdΜΦ")
AnnotationAssertion(rdfs:label obo:CL_0000879 "meningeal macrophage")
EquivalentClasses(obo:CL_0000879 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002360) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
SubClassOf(obo:CL_0000879 obo:CL_4042003)

# Class: obo:CL_0000880 (choroid plexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:9550136") obo:IAO_0000115 obo:CL_0000880 "A border associated macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This central nervous system macrophage has a star-like shaped body and expresses scavenger receptors.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000880 "cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_0000880 "choroid plexus macrophage")
EquivalentClasses(obo:CL_0000880 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001886) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))

# Class: obo:CL_0000881 (perivascular macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16507898") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000881 "A border associated macrophage that is adjacent to a small blood vessel of a brain. A perivascular macrophage expresses the markers CD14, CD16 and CD163. In homeostatic conditions, this central nervous system macrophage has a non-motile cell body with extending and retracting projections through the blood vessel wall.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000881 "pvMΦ")
AnnotationAssertion(rdfs:label obo:CL_0000881 "perivascular macrophage")
EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
SubClassOf(obo:CL_0000881 obo:CL_4033054)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_4042003)

# Class: obo:CL_0000882 (thymic medullary macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9048205") obo:IAO_0000115 obo:CL_0000882 "A thymic macrophage found in the thymic medulla.")
AnnotationAssertion(rdfs:label obo:CL_0000882 "thymic medullary macrophage")
EquivalentClasses(obo:CL_0000882 ObjectIntersectionOf(obo:CL_0000866 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000882 obo:CL_0000866)

# Class: obo:CL_0000883 (thymic cortical macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9048205") obo:IAO_0000115 obo:CL_0000883 "A thymic macrophage found in the thymic cortex.")
AnnotationAssertion(rdfs:label obo:CL_0000883 "thymic cortical macrophage")
EquivalentClasses(obo:CL_0000883 ObjectIntersectionOf(obo:CL_0000866 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002123)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000883 obo:CL_0000866)

# Class: obo:CL_0000884 (mucosa-associated lymphoid tissue macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19906191") obo:IAO_0000115 obo:CL_0000884 "A tissue-resident macrophage found in the mucosa associated lymphoid tissue.")
AnnotationAssertion(rdfs:label obo:CL_0000884 "mucosa-associated lymphoid tissue macrophage")
EquivalentClasses(obo:CL_0000884 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001961)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000884 obo:CL_0000867)

# Class: obo:CL_0000885 (gut-associated lymphoid tissue macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19906191") obo:IAO_0000115 obo:CL_0000885 "A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut.")
AnnotationAssertion(rdfs:label obo:CL_0000885 "gut-associated lymphoid tissue macrophage")
EquivalentClasses(obo:CL_0000885 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002387)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000885 obo:CL_0000884)

# Class: obo:CL_0000886 (nasal and broncial associated lymphoid tissue macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16048540") obo:IAO_0000115 obo:CL_0000886 "A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues.")
AnnotationAssertion(rdfs:label obo:CL_0000886 "nasal and broncial associated lymphoid tissue macrophage")
EquivalentClasses(obo:CL_0000886 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002395)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000886 obo:CL_0000884)

# Class: obo:CL_0000887 (lymph node subcapsular sinus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:14668803") Annotation(oboInOwl:hasDbXref "PMID:17934446") Annotation(oboInOwl:hasDbXref "PMID:20228797") obo:IAO_0000115 obo:CL_0000887 "A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000887 "lymph node subcapsular sinus macrophage")
EquivalentClasses(obo:CL_0000887 ObjectIntersectionOf(obo:CL_0000868 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032816) ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0002194)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000887 obo:CL_0000868)

# Class: obo:CL_0000888 (lymph node tingible body macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19631584") obo:IAO_0000115 obo:CL_0000888 "A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers.")
AnnotationAssertion(rdfs:label obo:CL_0000888 "lymph node tingible body macrophage")
EquivalentClasses(obo:CL_0000888 ObjectIntersectionOf(obo:CL_0000868 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002006) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002905) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000888 obo:CL_0000868)

# Class: obo:CL_0000889 (myeloid suppressor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16168663") Annotation(oboInOwl:hasDbXref "PMID:17016554") Annotation(oboInOwl:hasDbXref "PMID:17016559") obo:IAO_0000115 obo:CL_0000889 "An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000889 "Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.")
AnnotationAssertion(rdfs:label obo:CL_0000889 "myeloid suppressor cell")
EquivalentClasses(obo:CL_0000889 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000889 obo:CL_0000766)

# Class: obo:CL_0000890 (M2 macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20510870") obo:IAO_0000115 obo:CL_0000890 "An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30861466") oboInOwl:hasExactSynonym obo:CL_0000890 "alternatively activated macrophage")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000890 "anti-inflammatory macrophage")
AnnotationAssertion(rdfs:comment obo:CL_0000890 "Role or process: tissue remodeling.")
AnnotationAssertion(rdfs:label obo:CL_0000890 "M2 macrophage")
EquivalentClasses(obo:CL_0000890 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001844) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048771)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000890 obo:CL_0000861)
SubClassOf(obo:CL_0000890 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0020017))

# Class: obo:CL_0000891 (foam cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000891 "A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000891 "BTO:0003872")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000891 "FMA:83586")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000891 "MESH:D005487")
AnnotationAssertion(rdfs:label obo:CL_0000891 "foam cell")
SubClassOf(obo:CL_0000891 obo:CL_0000000)

# Class: obo:CL_0000892 (smooth muscle cell derived foam cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:30664015") obo:IAO_0000115 obo:CL_0000892 "A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.")
AnnotationAssertion(rdfs:label obo:CL_0000892 "smooth muscle cell derived foam cell")
SubClassOf(obo:CL_0000892 obo:CL_0000891)
SubClassOf(obo:CL_0000892 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000192))

# Class: obo:CL_0000893 (thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:12415312") obo:IAO_0000115 obo:CL_0000893 "An immature T cell located in the thymus.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000893 "immature T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000893 "immature T lymphocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000893 "immature T-cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000893 "immature T-lymphocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "BTO:0001372")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "CALOHA:TS-1042")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "FMA:72202")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "MESH:D060168")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "XAO:0003159")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000893 "thymic lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000893 "thymocyte")
EquivalentClasses(obo:CL_0000893 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000893 obo:CL_0002420)

# Class: obo:CL_0000894 (DN1 thymic pro-T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000894 "A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "DN1 thymic pro-T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "DN1 thymic pro-T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "DN1 thymic pro-T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "DN1 thymic progenitor T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "DN1 thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "double negative 1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "preT.DN1.Th")
AnnotationAssertion(rdfs:label obo:CL_0000894 "DN1 thymic pro-T cell")
EquivalentClasses(obo:CL_0000894 ObjectIntersectionOf(obo:CL_0000827 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000894 obo:CL_0000827)
SubClassOf(obo:CL_0000894 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002425))

# Class: obo:CL_0000895 (naive thymus-derived CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19100699") Annotation(oboInOwl:hasDbXref "PMID:22343568") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000895 "An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000895 "naive CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000895 "T.4Nve.Sp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0000895 "Th0")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000895 "naive thymus-derived CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000895 "naive thymus-derived CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000895 "naive thymus-derived CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000895 "These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000895 "naive thymus-derived CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000895 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000895 obo:CL_0000624)
SubClassOf(obo:CL_0000895 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002436))

# Class: obo:CL_0000896 (activated CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000896 "A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000896 "activated CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000896 "activated CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000896 "activated CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000896 "activated CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000896 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000896 obo:CL_0000624)
SubClassOf(obo:CL_0000896 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000895))

# Class: obo:CL_0000897 (CD4-positive, alpha-beta memory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000897 "A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell.")
AnnotationAssertion(terms:contributor obo:CL_0000897 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000897 "CD4-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000897 "CD4-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000897 "CD4-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000897 "T4.Mem.Sp")
AnnotationAssertion(rdfs:label obo:CL_0000897 "CD4-positive, alpha-beta memory T cell")
EquivalentClasses(obo:CL_0000897 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001603) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002286) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))
SubClassOf(obo:CL_0000897 obo:CL_0000624)

# Class: obo:CL_0000898 (naive T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19100699") obo:IAO_0000115 obo:CL_0000898 "Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000898 "naive T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000898 "naive T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000898 "naive T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000898 "naive T cell")
EquivalentClasses(obo:CL_0000898 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000898 obo:CL_0002419)

# Class: obo:CL_0000899 (T-helper 17 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20303875") Annotation(oboInOwl:hasDbXref "PMID:20969597") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000899 "CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000899 "MESH:D058504")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "IL-17-producing CD4+ T helper")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "T helper cells type 17")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "T(H)-17 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "Th17 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "helper T cell type 17")
AnnotationAssertion(rdfs:comment obo:CL_0000899 "This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000899 "T-helper 17 cell")
EquivalentClasses(obo:CL_0000899 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003455) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032620)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000899 obo:CL_0000492)
SubClassOf(obo:CL_0000899 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0000900 (naive thymus-derived CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:22343568") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000900 "A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000900 "naive CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000900 "naive thymus-dervied CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000900 "naive thymus-dervied CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000900 "naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000900 "T.8Nve.Sp")
AnnotationAssertion(rdfs:comment obo:CL_0000900 "This cell traffics in secondary lymphoid organs and blood.  This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000900 "naive thymus-derived CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000900 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000900 obo:CL_0000625)
SubClassOf(obo:CL_0000900 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002437))

# Class: obo:CL_0000901 (Tr1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16903904") obo:IAO_0000115 obo:CL_0000901 "CD4-positive alpha-beta T cell with regulatory function that produces IL-10.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "T-regulatory T cell type 1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "Tr1 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "Tr1 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "Tr1 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "Tr1 T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000901 "These cells are reportedly induced by IL-10 and are capable of producing IFN-gamma, IL-5, IL-10, and TGF-beta.)")
AnnotationAssertion(rdfs:label obo:CL_0000901 "Tr1 cell")
EquivalentClasses(obo:CL_0000901 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000901 obo:CL_0000624)
SubClassOf(obo:CL_0000901 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0000902 (induced T-regulatory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19464985") obo:IAO_0000115 obo:CL_0000902 "CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "iTreg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "induced Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "induced regulatory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "induced regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "induced regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000902 "induced regulatory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000902 "aTreg")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000902 "adaptive Treg")
AnnotationAssertion(rdfs:label obo:CL_0000902 "induced T-regulatory cell")
EquivalentClasses(obo:CL_0000902 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001852) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000902 obo:CL_0000792)

# Class: obo:CL_0000903 (natural T-regulatory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19464985") obo:IAO_0000115 obo:CL_0000903 "CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "nTreg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000903 "natural T-regulatory cell")
EquivalentClasses(obo:CL_0000903 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001852) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000903 obo:CL_0000792)

# Class: obo:CL_0000904 (central memory CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000904 "CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000904 "central memory CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central CD4-positive, alpha-beta memory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central CD4-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central CD4-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central CD4-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central memory CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central memory CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central memory CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000904 "This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD4+ T cell', but includes additional markers known to be expressed on central memory CD4+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000904 "central memory CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000904 ObjectIntersectionOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000904 obo:CL_0001204)

# Class: obo:CL_0000905 (effector memory CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000905 "CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000905 "effector memory CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector CD4-positive, alpha-beta memory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector CD4-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector CD4-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector CD4-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector memory CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector memory CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector memory CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000905 "This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD4+ T cell', but includes additional markers known to be expressed on effector memory CD4+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000905 "effector memory CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000905 ObjectIntersectionOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000905 obo:CL_0001204)

# Class: obo:CL_0000906 (activated CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000906 "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000906 "activated CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000906 "activated CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000906 "activated CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000906 "activated CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000906 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000906 obo:CL_0000625)
SubClassOf(obo:CL_0000906 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000900))

# Class: obo:CL_0000907 (central memory CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20146720") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000907 "CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000907 "central memory CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central CD8-positive, alpha-beta memory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central CD8-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central CD8-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central CD8-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central memory CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central memory CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central memory CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000907 "This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD8+ T cell', but includes additional markers known to be expressed on central memory CD8+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000907 "central memory CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000907 ObjectIntersectionOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000907 obo:CL_0001203)

# Class: obo:CL_0000908 (CD8-positive, alpha-beta cytokine secreting effector T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20146720") obo:IAO_0000115 obo:CL_0000908 "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T cell")
EquivalentClasses(obo:CL_0000908 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000908 obo:CL_0000625)
SubClassOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906))

# Class: obo:CL_0000909 (CD8-positive, alpha-beta memory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:20146720") obo:IAO_0000115 obo:CL_0000909 "A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell.")
AnnotationAssertion(terms:contributor obo:CL_0000909 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000909 "CD8-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000909 "CD8-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000909 "CD8-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000909 "T.8Mem.Sp")
AnnotationAssertion(rdfs:label obo:CL_0000909 "CD8-positive, alpha-beta memory T cell")
EquivalentClasses(obo:CL_0000909 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001603) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002286) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))

# Class: obo:CL_0000910 (cytotoxic T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:18395547") obo:IAO_0000115 obo:CL_0000910 "A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000910 "BTO:0000289")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000910 "CALOHA:TS-0190")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000910 "FMA:70573")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000910 "cytotoxic T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000910 "cytotoxic T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000910 "cytotoxic T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000910 "cytotoxic T cell")
EquivalentClasses(obo:CL_0000910 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000910 obo:CL_0000911)

# Class: obo:CL_0000911 (effector T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:PAM-ADD") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0877799148") Annotation(oboInOwl:hasDbXref "PMID:18395547") obo:IAO_0000115 obo:CL_0000911 "A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000911 "effector T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000911 "effector T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000911 "effector T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000911 "effector T cell")
EquivalentClasses(obo:CL_0000911 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0045026) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000911 obo:CL_0002419)

# Class: obo:CL_0000912 (helper T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:18395547") obo:IAO_0000115 obo:CL_0000912 "A effector T cell that provides help in the form of secreted cytokines to other immune cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000912 "BTO:0002417")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000912 "MESH:D006377")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "T-helper cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "helper T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "helper T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "helper T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000912 "helper T cell")
EquivalentClasses(obo:CL_0000912 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000912 obo:CL_0000911)

# Class: obo:CL_0000913 (effector memory CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20146720") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000913 "CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000913 "effector memory CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector CD8-positive, alpha-beta memory T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector CD8-positive, alpha-beta memory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector CD8-positive, alpha-beta memory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector CD8-positive, alpha-beta memory T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector memory CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector memory CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector memory CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000913 "This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD8+ T cell', but includes additional markers known to be expressed on effector memory CD8+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000913 "effector memory CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0000913 ObjectIntersectionOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000913 obo:CL_0001203)

# Class: obo:CL_0000914 (immature NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17589542") Annotation(oboInOwl:hasDbXref "PMID:19169262") obo:IAO_0000115 obo:CL_0000914 "An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NKT cell")
AnnotationAssertion(rdfs:label obo:CL_0000914 "immature NK T cell")
EquivalentClasses(obo:CL_0000914 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003469)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000914 obo:CL_0000790)
SubClassOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))

# Class: obo:CL_0000915 (CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11685222") obo:IAO_0000115 obo:CL_0000915 "An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0000915 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000915 obo:CL_0000797)
SubClassOf(obo:CL_0000915 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000811))

# Class: obo:CL_0000916 (dendritic epidermal T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11976459") obo:IAO_0000115 obo:CL_0000916 "A mature gamma-delta T cell located in the epidermis that regulates wound healing.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000916 "DETC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000916 "dendritic epidermal T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000916 "dendritic epidermal T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000916 "dendritic epidermal T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000916 "In mice, DETC have an invariant T cell receptor.")
AnnotationAssertion(rdfs:label obo:CL_0000916 "dendritic epidermal T cell")
EquivalentClasses(obo:CL_0000916 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001003) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060054)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000916 obo:CL_0000800)
SubClassOf(obo:CL_0000916 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002401))

# Class: obo:CL_0000917 (Tc1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:22343568") Annotation(oboInOwl:hasDbXref "PMID:9914231") obo:IAO_0000115 obo:CL_0000917 "A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000917 "BTO:0004793")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000917 "BTO:0004888")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000917 "FMA:84793")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "CD8-positive Th1 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "T-cytotoxic T cell type 1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000917 "Tc1 CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Tc1 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Tc1 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Tc1 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Tc1 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Th1 CD8-positive T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Th1 non-TFH CD8-positive T cell")
AnnotationAssertion(rdfs:comment obo:CL_0000917 "This cell type is compatible with the HIPC Lyoplate markers for 'Tc1 CD8+ T cell', but its logical definition includes additional known characteristics of Tc1 T cells.")
AnnotationAssertion(rdfs:label obo:CL_0000917 "Tc1 cell")
EquivalentClasses(obo:CL_0000917 ObjectIntersectionOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001835) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003463) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000917 obo:CL_0000908)

# Class: obo:CL_0000918 (Tc2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9914231") obo:IAO_0000115 obo:CL_0000918 "A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000918 "BTO:0004794")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000918 "FMA:84794")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "CD8-positive Th2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "T-cytotoxic T cell type 2")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Tc2 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Tc2 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Tc2 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Tc2 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Th2 CD8-positive T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Th2 non-TFH CD8-positive T cell")
AnnotationAssertion(rdfs:comment obo:CL_0000918 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell' (see CL:0001052), but includes the additional necessary and sufficient conditions to allow classification as a Tc2 T cell.")
AnnotationAssertion(rdfs:label obo:CL_0000918 "Tc2 cell")
EquivalentClasses(obo:CL_0000918 ObjectIntersectionOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001941) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000918 obo:CL_0000908)

# Class: obo:CL_0000919 (CD8-positive, CD25-positive, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19118505") obo:IAO_0000115 obo:CL_0000919 "A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8+CD25+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25-positive Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0000919 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000919 obo:CL_0000795)
SubClassOf(obo:CL_0000919 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906))

# Class: obo:CL_0000920 (CD8-positive, CD28-negative, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19118505") obo:IAO_0000115 obo:CL_0000920 "CD8-positive, alpha-beta positive regulatory T cell with the phenotype CD28-negative and FoxP3-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8+CD28- Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0000920 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001841)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000920 obo:CL_0000795)
SubClassOf(obo:CL_0000920 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906))

# Class: obo:CL_0000921 (type I NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15039760") obo:IAO_0000115 obo:CL_0000921 "An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000921 "classical NK T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000921 "type I NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000921 "type I NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000921 "type I NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000921 "type I NKT cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000921 "invariant NK T cell")
AnnotationAssertion(rdfs:comment obo:CL_0000921 "In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24.")
AnnotationAssertion(rdfs:label obo:CL_0000921 "type I NK T cell")
EquivalentClasses(obo:CL_0000921 ObjectIntersectionOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043208)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000921 obo:CL_0000814)

# Class: obo:CL_0000922 (type II NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15039760") obo:IAO_0000115 obo:CL_0000922 "An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NKT cell")
AnnotationAssertion(rdfs:label obo:CL_0000922 "type II NK T cell")
EquivalentClasses(obo:CL_0000922 ObjectIntersectionOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002288)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000922 obo:CL_0000814)

# Class: obo:CL_0000923 (CD4-positive type I NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000923 "A type I NK T cell that has the phenotype CD4-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000923 "CD4-positive type I NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000923 "CD4-positive type I NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000923 "CD4-positive type I NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000923 "CD4-positive type I NKT cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000923 "NKT.4+.SP")
AnnotationAssertion(rdfs:label obo:CL_0000923 "CD4-positive type I NK T cell")
EquivalentClasses(obo:CL_0000923 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000923 obo:CL_0000921)

# Class: obo:CL_0000924 (CD4-negative, CD8-negative type I NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:18997862") obo:IAO_0000115 obo:CL_0000924 "A type I NK T cell that has the phenotype CD4-negative and CD8-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000924 "CD4-negative, CD8-negative type I NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000924 "CD4-negative, CD8-negative type I NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000924 "CD4-negative, CD8-negative type I NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000924 "CD4-negative, CD8-negative type I NKT cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000924 "NKT.4-.Sp")
AnnotationAssertion(rdfs:label obo:CL_0000924 "CD4-negative, CD8-negative type I NK T cell")
EquivalentClasses(obo:CL_0000924 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000924 obo:CL_0000921)

# Class: obo:CL_0000925 (activated CD4-positive type I NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000925 "A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-positive type I NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-positive type I NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-positive type I NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-positive type I NKT cell")
AnnotationAssertion(rdfs:label obo:CL_0000925 "activated CD4-positive type I NK T cell")
EquivalentClasses(obo:CL_0000925 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000925 obo:CL_0000921)
SubClassOf(obo:CL_0000925 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000923))

# Class: obo:CL_0000926 (CD4-positive type I NK T cell secreting interferon-gamma)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000926 "A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NK T cell secreting IFN-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NK T lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NK T-cell secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NK T-lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NKT cell secreting interferon-gamma")
AnnotationAssertion(rdfs:label obo:CL_0000926 "CD4-positive type I NK T cell secreting interferon-gamma")
EquivalentClasses(obo:CL_0000926 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002827) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000926 obo:CL_0000921)
SubClassOf(obo:CL_0000926 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000925))

# Class: obo:CL_0000927 (CD4-positive type I NK T cell secreting interleukin-4)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000927 "A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NK T cell secreting IL-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NK T lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NK T-cell secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NK T-lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NKT cell secreting interleukin-4")
AnnotationAssertion(rdfs:label obo:CL_0000927 "CD4-positive type I NK T cell secreting interleukin-4")
EquivalentClasses(obo:CL_0000927 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032616) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000927 obo:CL_0000921)
SubClassOf(obo:CL_0000927 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000925))

# Class: obo:CL_0000928 (activated CD4-negative, CD8-negative type I NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000928 "A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negative, CD8-negative type I NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negative, CD8-negative type I NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negative, CD8-negative type I NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negative, CD8-negative type I NKT cell")
AnnotationAssertion(rdfs:label obo:CL_0000928 "activated CD4-negative, CD8-negative type I NK T cell")
EquivalentClasses(obo:CL_0000928 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002369)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000928 obo:CL_0000921)
SubClassOf(obo:CL_0000928 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000924))

# Class: obo:CL_0000929 (CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000929 "A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma")
AnnotationAssertion(rdfs:label obo:CL_0000929 "CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma")
EquivalentClasses(obo:CL_0000929 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002827) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000929 obo:CL_0000921)
SubClassOf(obo:CL_0000929 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000928))

# Class: obo:CL_0000930 (CD4-negative, CD8-negative type I NK T cell secreting interleukin-4)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17303398") obo:IAO_0000115 obo:CL_0000930 "A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NK T cell secreting IL-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NKT cell secreting interleukin-4")
AnnotationAssertion(rdfs:label obo:CL_0000930 "CD4-negative, CD8-negative type I NK T cell secreting interleukin-4")
EquivalentClasses(obo:CL_0000930 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000930 obo:CL_0000921)
SubClassOf(obo:CL_0000930 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000928))

# Class: obo:CL_0000931 (activated type II NK T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17964217") obo:IAO_0000115 obo:CL_0000931 "A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II NK T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II NK T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II NK T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II NKT cell")
AnnotationAssertion(rdfs:label obo:CL_0000931 "activated type II NK T cell")
EquivalentClasses(obo:CL_0000931 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002369)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000931 obo:CL_0000922)

# Class: obo:CL_0000932 (type II NK T cell secreting interferon-gamma)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17964217") obo:IAO_0000115 obo:CL_0000932 "A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NK T cell secreting IFN-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NK T lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NK T-cell secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NK T-lymphocyte secreting interferon-gamma")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NKT cell secreting interferon-gamma")
AnnotationAssertion(rdfs:label obo:CL_0000932 "type II NK T cell secreting interferon-gamma")
EquivalentClasses(obo:CL_0000932 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000932 obo:CL_0000922)
SubClassOf(obo:CL_0000932 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000931))

# Class: obo:CL_0000933 (type II NK T cell secreting interleukin-4)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17964217") obo:IAO_0000115 obo:CL_0000933 "A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NK T cell secreting IL-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NK T lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NK T-cell secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NK T-lymphocyte secreting interleukin-4")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NKT cell secreting interleukin-4")
AnnotationAssertion(rdfs:label obo:CL_0000933 "type II NK T cell secreting interleukin-4")
EquivalentClasses(obo:CL_0000933 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000933 obo:CL_0000922)
SubClassOf(obo:CL_0000933 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000931))

# Class: obo:CL_0000934 (CD4-positive, alpha-beta cytotoxic T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:18440213") obo:IAO_0000115 obo:CL_0000934 "A CD4-positive, alpha-beta T cell that has cytotoxic function.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T cell")
EquivalentClasses(obo:CL_0000934 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000934 obo:CL_0000624)
SubClassOf(obo:CL_0000934 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0000935 (CD4-negative, CD8-negative, alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11685222") obo:IAO_0000115 obo:CL_0000935 "A CD4-negative, CD8-negative, alpha-beta intraepithelial T cell that is found in the columnar epithelium of the gastrointestinal tract.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0000935 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025403)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000935 obo:CL_0000797)

# Class: obo:CL_0000936 (early lymphoid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0000936 "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000936 "lymphoid-primed multipotent progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000936 "ELP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18371378") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000936 "GMLP")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000936 "LMPP")
AnnotationAssertion(rdfs:comment obo:CL_0000936 "Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000936 "early lymphoid progenitor")
EquivalentClasses(obo:CL_0000936 ObjectIntersectionOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000936 obo:CL_0000837)
SubClassOf(obo:CL_0000936 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002035))

# Class: obo:CL_0000937 (pre-natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:17100874") obo:IAO_0000115 obo:CL_0000937 "Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000937 "pre-NK cell")
AnnotationAssertion(rdfs:comment obo:CL_0000937 "These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high.")
AnnotationAssertion(rdfs:label obo:CL_0000937 "pre-natural killer cell")
EquivalentClasses(obo:CL_0000937 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001381) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065)))

# Class: obo:CL_0000938 (CD16-negative, CD56-bright natural killer cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19796267") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000938 "NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000938 "CD16-CD56bright NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000938 "CD16-negative, CD56-bright NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000938 "CD56-bright cytokine secreting NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000938 "CD56-bright cytokine secreting natural killer cell")
AnnotationAssertion(rdfs:comment obo:CL_0000938 "This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types.")
AnnotationAssertion(rdfs:label obo:CL_0000938 "CD16-negative, CD56-bright natural killer cell, human")
EquivalentClasses(obo:CL_0000938 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001319) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001024)))

# Class: obo:CL_0000939 (CD16-positive, CD56-dim natural killer cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19796267") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000939 "A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0000939 "CD16+CD56+ NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "CD16-positive, CD56-dim NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "CD16-positive, CD56-low NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "CD16-positive, CD56-low natural killer cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "CD16-positive, CD56-positive NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "CD16-positive, CD56-positive natural killer cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "cytotoxic CD56-dim NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000939 "cytotoxic CD56-dim natural killer cell")
AnnotationAssertion(rdfs:comment obo:CL_0000939 "This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types.")
AnnotationAssertion(rdfs:label obo:CL_0000939 "CD16-positive, CD56-dim natural killer cell, human")
EquivalentClasses(obo:CL_0000939 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042267) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001024)))

# Class: obo:CL_0000940 (mucosal-associated invariant T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19416870") Annotation(oboInOwl:hasDbXref "PMID:33352411") obo:IAO_0000115 obo:CL_0000940 "An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. This cell develops from double-positive, alpha-beta thymocyte.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal-associated invariant T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal-associated invariant T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal-associated invariant T-lymphocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:40781543") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000940 "MAIT")
AnnotationAssertion(rdfs:label obo:CL_0000940 "mucosal-associated invariant T cell")
EquivalentClasses(obo:CL_0000940 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002227) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032394) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000940 obo:CL_0000791)
SubClassOf(obo:CL_0000940 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))

# Class: obo:CL_0000941 (thymic conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19273629") obo:IAO_0000115 obo:CL_0000941 "A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative.")
AnnotationAssertion(rdfs:comment obo:CL_0000941 "In the mouse this cell expresses CD8-alpha-alpha.")
AnnotationAssertion(rdfs:label obo:CL_0000941 "thymic conventional dendritic cell")
EquivalentClasses(obo:CL_0000941 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000941 obo:CL_0000990)
SubClassOf(obo:CL_0000941 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894))

# Class: obo:CL_0000942 (thymic plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19941119") obo:IAO_0000115 obo:CL_0000942 "A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000942 "thymic plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000942 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000942 obo:CL_0000784)
SubClassOf(obo:CL_0000942 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894))

# Class: obo:CL_0000943 (Be1 Cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11101868") Annotation(oboInOwl:hasDbXref "PMID:20224569") obo:IAO_0000115 obo:CL_0000943 "A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11101868") Annotation(oboInOwl:hasDbXref "PMID:20224569") oboInOwl:hasExactSynonym obo:CL_0000943 "B effector 1 cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000943 "B effector cell type 1")
AnnotationAssertion(rdfs:comment obo:CL_0000943 "Be1 cells are also reportedly capable of secreting IL-6, IL-10, and IL-12. They are also reportedly CD11b-negative and B220-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000943 "Be1 Cell")
EquivalentClasses(obo:CL_0000943 ObjectIntersectionOf(obo:CL_0000968 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032623) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045627)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000943 obo:CL_0000968)

# Class: obo:CL_0000944 (Be2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11101868") Annotation(oboInOwl:hasDbXref "PMID:20224569") obo:IAO_0000115 obo:CL_0000944 "A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11101868") Annotation(oboInOwl:hasDbXref "PMID:20224569") oboInOwl:hasExactSynonym obo:CL_0000944 "B effector 2 cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000944 "B effector cell type 2")
AnnotationAssertion(rdfs:comment obo:CL_0000944 "Be2 cells are also reportedly capable of secreting IL-13 and TNF. They are also reportedly CD11b-negative and B220-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000944 "Be2 cell")
EquivalentClasses(obo:CL_0000944 ObjectIntersectionOf(obo:CL_0000968 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032623) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045630)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000944 obo:CL_0000968)

# Class: obo:CL_0000945 (lymphocyte of B lineage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000945 "A lymphocyte of B lineage with the commitment to express an immunoglobulin complex.")
AnnotationAssertion(rdfs:comment obo:CL_0000945 "Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells).  Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex).")
AnnotationAssertion(rdfs:label obo:CL_0000945 "lymphocyte of B lineage")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000945 obo:CL_0000542)
SubClassOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826))

# Class: obo:CL_0000946 (antibody secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000946 "A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin.")
AnnotationAssertion(rdfs:label obo:CL_0000946 "antibody secreting cell")
EquivalentClasses(obo:CL_0000946 ObjectIntersectionOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0042571)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000946 obo:CL_0000945)

# Class: obo:CL_0000947 (IgE plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000947 "A long lived plasma cell that secretes IgE.")
AnnotationAssertion(rdfs:label obo:CL_0000947 "IgE plasma cell")
EquivalentClasses(obo:CL_0000947 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000947 obo:CL_0000974)

# Class: obo:CL_0000948 (IgE memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") obo:IAO_0000115 obo:CL_0000948 "A class switched memory B cell that expresses IgE on the cell surface.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "IgE memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "IgE memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "IgE memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000948 "IgE memory B cell")
EquivalentClasses(obo:CL_0000948 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071742)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000948 obo:CL_0000972)
SubClassOf(obo:CL_0000948 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738))

# Class: obo:CL_0000949 (IgD plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000949 "A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult.")
AnnotationAssertion(rdfs:label obo:CL_0000949 "IgD plasmablast")
EquivalentClasses(obo:CL_0000949 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071739)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000949 obo:CL_0000980)

# Class: obo:CL_0000950 (IgE plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000950 "A plasmablast that secretes IgE.")
AnnotationAssertion(rdfs:label obo:CL_0000950 "IgE plasmablast")
EquivalentClasses(obo:CL_0000950 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000950 obo:CL_0000980)

# Class: obo:CL_0000951 (IgE short lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000951 "A short lived plasma cell that secretes IgE.")
AnnotationAssertion(rdfs:label obo:CL_0000951 "IgE short lived plasma cell")
EquivalentClasses(obo:CL_0000951 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000951 obo:CL_0000975)

# Class: obo:CL_0000952 (preBCR-positive large pre-B-II cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000952 "An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.")
AnnotationAssertion(rdfs:label obo:CL_0000952 "preBCR-positive large pre-B-II cell")
EquivalentClasses(obo:CL_0000952 ObjectIntersectionOf(obo:CL_0000957 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071708) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001859)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000952 obo:CL_0000957)

# Class: obo:CL_0000953 (preBCR-negative large pre-B-II cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000953 "A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.")
AnnotationAssertion(rdfs:label obo:CL_0000953 "preBCR-negative large pre-B-II cell")
EquivalentClasses(obo:CL_0000953 ObjectIntersectionOf(obo:CL_0000957 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071708) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0035369) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001859)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000953 obo:CL_0000957)

# Class: obo:CL_0000954 (small pre-B-II cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000954 "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000954 "small pre-BII cell")
AnnotationAssertion(rdfs:comment obo:CL_0000954 "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000954 "small pre-B-II cell")
EquivalentClasses(obo:CL_0000954 ObjectIntersectionOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003457) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003460) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019815) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0071708)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000954 obo:CL_0000955)

# Class: obo:CL_0000955 (pre-B-II cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000955 "A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000955 "BTO:0001133")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000955 "CALOHA:TS-0819")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000955 "pre-B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000955 "pre-BII cell")
AnnotationAssertion(rdfs:comment obo:CL_0000955 "pre-B-II cell are also reportedly CD19-positive, CD22-positive, CD38-positive, CD45-positive, and CD48-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000955 "pre-B-II cell")
EquivalentClasses(obo:CL_0000955 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000006611) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0071707)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000955 obo:CL_0000817)
SubClassOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826))
DisjointClasses(obo:CL_0000955 obo:CL_0000956)

# Class: obo:CL_0000956 (pre-B-I cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:20839338") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000956 "A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000956 "pre-BI cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11244048") oboInOwl:hasRelatedSynonym obo:CL_0000956 "pro-B cell (Philadelphia nomenclature)")
AnnotationAssertion(rdfs:comment obo:CL_0000956 "Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000956 "pre-B-I cell")
EquivalentClasses(obo:CL_0000956 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003457) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003460) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000006611) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0071707) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001859)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000956 obo:CL_0000817)
SubClassOf(obo:CL_0000956 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826))

# Class: obo:CL_0000957 (large pre-B-II cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000957 "A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11244048") oboInOwl:hasBroadSynonym obo:CL_0000957 "large pre-B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000957 "large pre-BII cell")
AnnotationAssertion(rdfs:comment obo:CL_0000957 "Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000957 "large pre-B-II cell")
EquivalentClasses(obo:CL_0000957 ObjectIntersectionOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000003457) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000003460) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0046651)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000957 obo:CL_0000955)

# Class: obo:CL_0000958 (T1 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2193793") Annotation(oboInOwl:hasDbXref "PMID:12810111") obo:IAO_0000115 obo:CL_0000958 "A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000958 "T1 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000958 "T1 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000958 "T1 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000958 "transitional stage 1 B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000958 "T1 B cells are also reportedly CD10-negative/positive??, CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000958 "T1 B cell")
EquivalentClasses(obo:CL_0000958 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001338) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000958 obo:CL_0000818)

# Class: obo:CL_0000959 (T2 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2193793") Annotation(oboInOwl:hasDbXref "PMID:12810111") obo:IAO_0000115 obo:CL_0000959 "A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000959 "T2 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000959 "T2 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000959 "T2 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000959 "transitional stage 2 B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000959 "T2 B cells are also reportedly CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000959 "T2 B cell")
EquivalentClasses(obo:CL_0000959 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000959 obo:CL_0000818)
SubClassOf(obo:CL_0000959 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000958))

# Class: obo:CL_0000960 (T3 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:12810111") Annotation(oboInOwl:hasDbXref "PMID:17174121") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000960 "A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM).")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17174121") oboInOwl:hasExactSynonym obo:CL_0000960 "An1 B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "T3 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "T3 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "T3 B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "transitional stage 3 B cell")
AnnotationAssertion(rdfs:label obo:CL_0000960 "T3 B cell")
EquivalentClasses(obo:CL_0000960 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002515) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000960 obo:CL_0000818)
SubClassOf(obo:CL_0000960 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000959))

# Class: obo:CL_0000961 (Bm1 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:17992590") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000961 "A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000961 "Bm1 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000961 "Bm1 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000961 "Bm1 B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000961 "These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000961 "Bm1 B cell")
EquivalentClasses(obo:CL_0000961 ObjectIntersectionOf(obo:CL_0000843 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000961 obo:CL_0000843)
SubClassOf(obo:CL_0000961 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818))

# Class: obo:CL_0000962 (Bm2 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:17992590") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000962 "A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000962 "Bm2 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000962 "Bm2 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000962 "Bm2 B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000962 "These cells are also CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000962 "Bm2 B cell")
EquivalentClasses(obo:CL_0000962 ObjectIntersectionOf(obo:CL_0000843 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000962 obo:CL_0000843)
SubClassOf(obo:CL_0000962 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000961))

# Class: obo:CL_0000963 (Bm3-delta B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9280752") obo:IAO_0000115 obo:CL_0000963 "A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000963 "Bm3-delta B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000963 "Bm3-delta B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000963 "Bm3-delta B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000963 "Bm3-delta B cell")
EquivalentClasses(obo:CL_0000963 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000963 obo:CL_0000844)
SubClassOf(obo:CL_0000963 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000965))

# Class: obo:CL_0000964 (Bm2' B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:17992590") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000964 "A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000964 "Bm2' B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000964 "Bm2' B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000964 "Bm2-prime B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000964 "Bm2-prime B-lymphocyte")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000964 "germinal center founder cell")
AnnotationAssertion(rdfs:comment obo:CL_0000964 "Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000964 "Bm2' B cell")
EquivalentClasses(obo:CL_0000964 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002634)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000964 obo:CL_0000844)
SubClassOf(obo:CL_0000964 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000962))

# Class: obo:CL_0000965 (Bm3 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000965 "A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000965 "Bm3 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000965 "Bm3 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000965 "Bm3 B-lymphocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8006591") oboInOwl:hasRelatedSynonym obo:CL_0000965 "centroblast")
AnnotationAssertion(rdfs:comment obo:CL_0000965 "Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000965 "Bm3 B cell")
EquivalentClasses(obo:CL_0000965 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000003516) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0016446)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000965 obo:CL_0000844)
SubClassOf(obo:CL_0000965 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000964))

# Class: obo:CL_0000966 (Bm4 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000966 "A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000966 "Bm4 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000966 "Bm4 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000966 "Bm4 B-lymphocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17992590") oboInOwl:hasRelatedSynonym obo:CL_0000966 "centrocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000966 "Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000966 "Bm4 B cell")
EquivalentClasses(obo:CL_0000966 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000003516) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0016446)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000966 obo:CL_0000844)
SubClassOf(obo:CL_0000966 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000963))

# Class: obo:CL_0000967 (Bm5 B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11564773") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:19350211") Annotation(oboInOwl:hasDbXref "PMID:31681331") Annotation(oboInOwl:hasDbXref "PMID:8006591") obo:IAO_0000115 obo:CL_0000967 "A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000967 "Bm5 B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000967 "Bm5 B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000967 "Bm5 B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000967 "Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000967 "Bm5 B cell")
EquivalentClasses(obo:CL_0000967 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002314) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0016446)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000967 obo:CL_0000787)
SubClassOf(obo:CL_0000967 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000966))

# Class: obo:CL_0000968 (Be cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11101868") Annotation(oboInOwl:hasDbXref "PMID:20224569") obo:IAO_0000115 obo:CL_0000968 "A mature B cell that produces cytokines that can influence CD4 T cell differentiation.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "B effector cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000968 "Be cell")
EquivalentClasses(obo:CL_0000968 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043370)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000968 obo:CL_0000785)

# Class: obo:CL_0000969 (regulatory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "MESH:D060151") Annotation(oboInOwl:hasDbXref "PMID:11869683") Annotation(oboInOwl:hasDbXref "PMID:18482568") Annotation(oboInOwl:hasDbXref "PMID:20224569") Annotation(oboInOwl:hasDbXref "PMID:20809522") obo:IAO_0000115 obo:CL_0000969 "A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "B(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "B10 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "Breg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "regulatory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "regulatory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "regulatory B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000969 "Regulatory B cells reportedly represent 1-2% of the spleen and 7-8% of the peritoneal B220-positive cells in mice. They are also found in the bone marrow, lymph node, and blood of mice. These cells are also reportedly capable of secreting IL-10 and are reportedly CD5-positive, CD21-positive, CD24-positive, CD93-negative, B220-positive, IgM-positive, and IgD-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000969 "regulatory B cell")
EquivalentClasses(obo:CL_0000969 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002028) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000969 obo:CL_0000785)

# Class: obo:CL_0000970 (unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0000970 "An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0000970 "IgD+ memory B cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HP:0032126") oboInOwl:hasExactSynonym obo:CL_0000970 "non-class-switched memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000970 "unswitched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000970 "unswitched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000970 "unswitched memory B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000970 "This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000970 "unswitched memory B cell")
EquivalentClasses(obo:CL_0000970 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071742) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071745) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000970 obo:CL_0000787)
SubClassOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980))

# Class: obo:CL_0000971 (IgM memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") Annotation(oboInOwl:hasDbXref "PMID:19447676") obo:IAO_0000115 obo:CL_0000971 "An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "IgM memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "IgM memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "IgM memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "memory IgM B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "memory IgM B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "memory IgM B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000971 "memory IgM B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000971 "IgM memory B cells are also reportedly CD1c-positive, CD95-positive, CD80-positive, CD84-positive, CD86-positive, CD150-negative, CD229-positive, CD289-positive, and CD290-positive. Transcription factors: Notch2-positive, PAX5-positive, SpiB-positive, Ets1-positive, and OBF1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000971 "IgM memory B cell")
EquivalentClasses(obo:CL_0000971 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753)))
SubClassOf(obo:CL_0000971 obo:CL_0000787)

# Class: obo:CL_0000972 (class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") Annotation(oboInOwl:hasDbXref "PMID:20933013") Annotation(oboInOwl:hasDbXref "PMID:9295047") obo:IAO_0000115 obo:CL_0000972 "A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000972 "class switched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000972 "class switched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000972 "class switched memory B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000972 "Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000972 "class switched memory B cell")
EquivalentClasses(obo:CL_0000972 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045190)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000972 obo:CL_0000787)
SubClassOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000970))

# Class: obo:CL_0000973 (IgA memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") obo:IAO_0000115 obo:CL_0000973 "A class switched memory B cell that expresses IgA.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "IgA memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "IgA memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "IgA memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "memory IgA B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "memory IgA B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "memory IgA B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "memory IgA B-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000973 "IgA memory B cell are also reportedly RORalpha-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000973 "IgA memory B cell")
EquivalentClasses(obo:CL_0000973 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071745)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000973 obo:CL_0000972)
SubClassOf(obo:CL_0000973 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738))

# Class: obo:CL_0000974 (long lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:9780781765190") Annotation(oboInOwl:hasDbXref "PMID:16014527") obo:IAO_0000115 obo:CL_0000974 "A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow.")
AnnotationAssertion(rdfs:label obo:CL_0000974 "long lived plasma cell")
EquivalentClasses(obo:CL_0000974 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019814) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001208) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001002)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000974 obo:CL_0000786)
SubClassOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000975))

# Class: obo:CL_0000975 (short lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16014527") obo:IAO_0000115 obo:CL_0000975 "A fully differentiated plasma cell that lives for months.")
AnnotationAssertion(rdfs:label obo:CL_0000975 "short lived plasma cell")
EquivalentClasses(obo:CL_0000975 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001604)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000975 obo:CL_0000786)
SubClassOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980))

# Class: obo:CL_0000976 (IgA short lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000976 "A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system.")
AnnotationAssertion(rdfs:label obo:CL_0000976 "IgA short lived plasma cell")
EquivalentClasses(obo:CL_0000976 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000976 obo:CL_0000975)

# Class: obo:CL_0000977 (IgG short lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000977 "A short lived plasma cell that secretes IgG.")
AnnotationAssertion(rdfs:label obo:CL_0000977 "IgG short lived plasma cell")
EquivalentClasses(obo:CL_0000977 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000977 obo:CL_0000975)

# Class: obo:CL_0000978 (IgM short lived plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000978 "A short lived plasma cell that secretes IgM.")
AnnotationAssertion(rdfs:label obo:CL_0000978 "IgM short lived plasma cell")
EquivalentClasses(obo:CL_0000978 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000978 obo:CL_0000975)

# Class: obo:CL_0000979 (IgG memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781765196") obo:IAO_0000115 obo:CL_0000979 "An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "IgG memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "IgG memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "IgG memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000979 "IgG memory B cell")
EquivalentClasses(obo:CL_0000979 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071735)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000979 obo:CL_0000972)

# Class: obo:CL_0000980 (plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2673126") obo:IAO_0000115 obo:CL_0000980 "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000980 "CD20-negative B cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000980 "FMA:84371")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000980 "CD27-positive, CD38-positive, CD20-negative B cell")
AnnotationAssertion(rdfs:comment obo:CL_0000980 "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative.")
AnnotationAssertion(rdfs:label obo:CL_0000980 "plasmablast")
EquivalentClasses(obo:CL_0000980 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0042571) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001963)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000980 obo:CL_0000785)
SubClassOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000785))

# Class: obo:CL_0000981 (double negative memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000981 "A memory B cell with the phenotype IgD-negative and CD27-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "dn memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "dn memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "dn memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "dn memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "double negative memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "double negative memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "double negative memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0000981 "double negative memory B cell")
EquivalentClasses(obo:CL_0000981 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000981 obo:CL_0000787)

# Class: obo:CL_0000982 (IgG plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000982 "A plasmablast that secretes IgG.")
AnnotationAssertion(rdfs:label obo:CL_0000982 "IgG plasmablast")
EquivalentClasses(obo:CL_0000982 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000982 obo:CL_0000980)

# Class: obo:CL_0000983 (IgM plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000983 "A plasmablast that secretes IgM.")
AnnotationAssertion(rdfs:label obo:CL_0000983 "IgM plasmablast")
EquivalentClasses(obo:CL_0000983 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000983 obo:CL_0000980)

# Class: obo:CL_0000984 (IgA plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000984 "A plasmablast that secretes IgA.")
AnnotationAssertion(rdfs:label obo:CL_0000984 "IgA plasmablast")
EquivalentClasses(obo:CL_0000984 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000984 obo:CL_0000980)

# Class: obo:CL_0000985 (IgG plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000985 "A fully differentiated plasma cell that secretes IgG.")
AnnotationAssertion(rdfs:label obo:CL_0000985 "IgG plasma cell")
EquivalentClasses(obo:CL_0000985 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000985 obo:CL_0000974)

# Class: obo:CL_0000986 (IgM plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000986 "A fully differentiated plasma cell that secretes IgM.")
AnnotationAssertion(rdfs:label obo:CL_0000986 "IgM plasma cell")
EquivalentClasses(obo:CL_0000986 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000986 obo:CL_0000974)

# Class: obo:CL_0000987 (IgA plasma cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000987 "A fully differentiated plasma cell that secretes IgA.")
AnnotationAssertion(rdfs:label obo:CL_0000987 "IgA plasma cell")
EquivalentClasses(obo:CL_0000987 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000987 obo:CL_0000974)

# Class: obo:CL_0000988 (hematopoietic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000988 "A cell of a hematopoietic lineage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000988 "BTO:0000574")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000988 "CALOHA:TS-2017")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000988 "FMA:70366")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000988 "FMA:83598")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000988 "haematopoietic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000988 "haemopoietic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000988 "hemopoietic cell")
AnnotationAssertion(rdfs:label obo:CL_0000988 "hematopoietic cell")
SubClassOf(obo:CL_0000988 obo:CL_0000000)

# Class: obo:CL_0000989 (CD11c-low plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") Annotation(oboInOwl:hasDbXref "PMID:19243617") Annotation(oboInOwl:hasDbXref "PMID:34603298") obo:IAO_0000115 obo:CL_0000989 "CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative.")
AnnotationAssertion(rdfs:comment obo:CL_0000989 "Originally described in the dendritic cell ontology (DC_CL:0000001)(PMID:19243617). These cells are CD281-positive (TLR1), CD282-positive (TLR2), CD285-positive (TLR5), CD286-positive (TLR6), and CD288-positive (TLR8).")
AnnotationAssertion(rdfs:label obo:CL_0000989 "CD11c-low plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000989 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001013)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000989 obo:CL_0000784)
SubClassOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0000990 (conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000990 "Conventional dendritic cell is a dendritic cell that is CD11c-high.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000990 "interdigitating cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000990 "veiled cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000990 "FMA:84191")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000990 "DC1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000990 "cDC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000990 "dendritic reticular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000990 "type 1 DC")
AnnotationAssertion(rdfs:comment obo:CL_0000990 "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive.")
AnnotationAssertion(rdfs:label obo:CL_0000990 "conventional dendritic cell")
EquivalentClasses(obo:CL_0000990 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001013)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000990 obo:CL_0000451)

# Class: obo:CL_0000991 (CD11c-negative plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") Annotation(oboInOwl:hasDbXref "PMID:19243617") Annotation(oboInOwl:hasDbXref "PMID:29313948") obo:IAO_0000115 obo:CL_0000991 "CD11c-negative plasmacytoid dendritic cell is a leukocyte is CD11c-negative, CD45RA-positive, CD85g-positive(ILT7), CD123-positive, CD303-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000991 "CD303-positive dendritic cell")
AnnotationAssertion(rdfs:comment obo:CL_0000991 "Originally described in the dendritic cell ontology (DC_CL:0000004)(PMID:19243617). These cells are CD281-positive (TLR1), CD286-positive (TLR6), and CD290-positive (TLR10).")
AnnotationAssertion(rdfs:label obo:CL_0000991 "CD11c-negative plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000991 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001292) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001398) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032606)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000991 obo:CL_0000784)
SubClassOf(obo:CL_0000991 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_0000992 (immature CD11c-low plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000992 "Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low.")
AnnotationAssertion(rdfs:comment obo:CL_0000992 "Originally described in the dendritic cell ontology (DC_CL:0000006)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000992 "immature CD11c-low plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000992 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000992 obo:CL_0000989)
SubClassOf(obo:CL_0000992 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029))

# Class: obo:CL_0000993 (mature CD11c-low plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000993 "Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000993 "Originally described in the dendritic cell ontology (DC_CL:0000007)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000993 "mature CD11c-low plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000993 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000993 obo:CL_0000989)
SubClassOf(obo:CL_0000993 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000992))

# Class: obo:CL_0000994 (immature CD11c-negative plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000994 "Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0000994 "Originally described in the dendritic cell ontology (DC_CL:0000008)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000994 "immature CD11c-negative plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000994 ObjectIntersectionOf(obo:CL_0000991 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001438) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000994 obo:CL_0000991)
SubClassOf(obo:CL_0000994 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000995))

# Class: obo:CL_0000995 (CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor)

AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000995 "CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid")
AnnotationAssertion(rdfs:comment obo:CL_0000995 "Originally described in the dendritic cell ontology (DC_CL:1100000)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000995 "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor")
EquivalentClasses(obo:CL_0000995 ObjectUnionOf(obo:CL_0001021 obo:CL_0001026))
SubClassOf(obo:CL_0000995 obo:CL_0001060)

# Class: obo:CL_0000996 (mature CD11c-negative plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:15771572") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0000996 "Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0000996 "Originally described in the dendritic cell ontology (DC_CL:0000009)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000996 "mature CD11c-negative plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0000996 ObjectIntersectionOf(obo:CL_0000991 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000996 obo:CL_0000991)
SubClassOf(obo:CL_0000996 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000994))

# Class: obo:CL_0000997 (immature CD8-alpha-negative CD11b-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0000997 "Immature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0000997 "Originally described in the dendritic cell ontology (DC_CL:0000010)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000997 "immature CD8-alpha-negative CD11b-positive dendritic cell")
EquivalentClasses(obo:CL_0000997 ObjectIntersectionOf(obo:CL_0000999 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000997 obo:CL_0000999)
SubClassOf(obo:CL_0000997 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0000998 (CD8-alpha-negative CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0000998 "CD8-alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8-alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000998 "DC.8-4-11b-")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000998 "triple negative dendritic cell")
AnnotationAssertion(rdfs:comment obo:CL_0000998 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000011)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000998 "CD8-alpha-negative CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0000998 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002474)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000998 obo:CL_0000990)
SubClassOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0000999 (CD4-positive CD11b-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0000999 "CD8-alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8-alpha-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000999 "DC.4+")
AnnotationAssertion(rdfs:comment obo:CL_0000999 "Defined as having a disposition to secreting anti-inflammatory cytokines. These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000012)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0000999 "CD4-positive CD11b-positive dendritic cell")
EquivalentClasses(obo:CL_0000999 ObjectIntersectionOf(obo:CL_0002465 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001026) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050728)))
SubClassOf(obo:CL_0000999 obo:CL_0002465)
SubClassOf(obo:CL_0000999 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0001000 (CD8-alpha-positive CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001000 "CD8-alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8-alpha-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001000 "DC.8+")
AnnotationAssertion(rdfs:comment obo:CL_0001000 "Cells are defined as having a disposition to secreting inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000013)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001000 "CD8-alpha-positive CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0001000 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042590) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050729)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001000 obo:CL_0000990)
SubClassOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0001001 (immature CD8-alpha-negative CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001001 "Immature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001001 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000014)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001001 "immature CD8-alpha-negative CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0001001 ObjectIntersectionOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001001 obo:CL_0000998)
SubClassOf(obo:CL_0001001 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0001002 (mature CD8-alpha-negative CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001002 "Mature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001002 "These markers are associated with mouse cells. Defined as having a disposition to secretion of anti-inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000015)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001002 "mature CD8-alpha-negative CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0001002 ObjectIntersectionOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001002 obo:CL_0000998)
SubClassOf(obo:CL_0001002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001001))

# Class: obo:CL_0001003 (mature CD8-alpha-negative CD11b-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001003 "Mature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001003 "Originally described in the dendritic cell ontology (DC_CL:0000016)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001003 "mature CD8-alpha-negative CD11b-positive dendritic cell")
EquivalentClasses(obo:CL_0001003 ObjectIntersectionOf(obo:CL_0000999 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001003 obo:CL_0000999)
SubClassOf(obo:CL_0001003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000997))

# Class: obo:CL_0001004 (immature CD8-alpha-positive CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001004 "Immature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001004 "Originally described in the dendritic cell ontology (DC_CL:0000017)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001004 "immature CD8-alpha-positive CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0001004 ObjectIntersectionOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001004 obo:CL_0001000)
SubClassOf(obo:CL_0001004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0001005 (mature CD8-alpha-positive CD11b-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001005 "Mature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001005 "Originally described in the dendritic cell ontology (DC_CL:0000018)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001005 "mature CD8-alpha-positive CD11b-negative dendritic cell")
EquivalentClasses(obo:CL_0001005 ObjectIntersectionOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001005 obo:CL_0001000)
SubClassOf(obo:CL_0001005 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001004))

# Class: obo:CL_0001006 (dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001006 "Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001006 "BTO:0004812")
AnnotationAssertion(rdfs:comment obo:CL_0001006 "Originally described in the dendritic cell ontology (DC_CL:0000019)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD288-positive (TLR8), and CD289-positive (TLR9).")
AnnotationAssertion(rdfs:label obo:CL_0001006 "dermal dendritic cell")
EquivalentClasses(obo:CL_0001006 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001006 obo:CL_0000990)

# Class: obo:CL_0001007 (interstitial dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001007 "Interstitial dendritic cell is a conventional dendritic cell that is CD11b-positive, CD1a-positive, CD206-positive, CD209-positive, and CD36-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001007 "Originally described in the dendritic cell ontology (DC_CL:0000020)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10).")
AnnotationAssertion(rdfs:label obo:CL_0001007 "interstitial dendritic cell")
EquivalentClasses(obo:CL_0001007 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001300) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001905) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002025) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001007 obo:CL_0000990)

# Class: obo:CL_0001008 (Kit and Sca1-positive hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17952047") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0001008 "A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001008 "LSK stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001008 "Sca1-positive hematopoietic stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0001008 "Cell markers are associated with mouse hematopoietic stem cell. Originally described in the dendritic cell ontology (DC_CL:0000043)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001008 "Kit and Sca1-positive hematopoietic stem cell")
EquivalentClasses(obo:CL_0001008 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001308) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001896) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002977) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001008 obo:CL_0000037)
DisjointClasses(obo:CL_0001008 obo:CL_0001024)

# Class: obo:CL_0001009 (immature dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001009 "Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001009 "Originally described in the dendritic cell ontology (DC_CL:0000022)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001009 "immature dermal dendritic cell")
EquivalentClasses(obo:CL_0001009 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001009 obo:CL_0001006)
SubClassOf(obo:CL_0001009 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029))

# Class: obo:CL_0001010 (mature dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001010 "Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001010 "Originally described in the dendritic cell ontology (DC_CL:0000023)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001010 "mature dermal dendritic cell")
EquivalentClasses(obo:CL_0001010 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001010 obo:CL_0001006)
SubClassOf(obo:CL_0001010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001009))

# Class: obo:CL_0001011 (immature interstitial dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001011 "Immature interstitial dendritic cell is a interstitial dendritic cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001011 "Originally described in the dendritic cell ontology (DC_CL:0000024)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001011 "immature interstitial dendritic cell")
EquivalentClasses(obo:CL_0001011 ObjectIntersectionOf(obo:CL_0001007 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001011 obo:CL_0001007)
SubClassOf(obo:CL_0001011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001012))

# Class: obo:CL_0001012 (CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor)

AnnotationAssertion(rdfs:comment obo:CL_0001012 "Originally described in the dendritic cell ontology (DC_CL:1110000)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001012 "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor")
EquivalentClasses(obo:CL_0001012 ObjectUnionOf(obo:CL_0000557 obo:CL_0001027))
SubClassOf(obo:CL_0001012 obo:CL_0001060)

# Class: obo:CL_0001013 (mature interstitial dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001013 "Mature interstitial dendritic cell is a interstitial dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001013 "Originally described in the dendritic cell ontology (DC_CL:0000025)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001013 "mature interstitial dendritic cell")
EquivalentClasses(obo:CL_0001013 ObjectIntersectionOf(obo:CL_0001007 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001013 obo:CL_0001007)
SubClassOf(obo:CL_0001013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001011))

# Class: obo:CL_0001014 (CD1a-positive Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001014 "CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001014 "CD1a-LC")
AnnotationAssertion(rdfs:comment obo:CL_0001014 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000026)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD286-positive (TLR6), CD287-positive (TLR7), and CD290-positive (TLR10). When activated, these cells are capable of producing IL-6, IL-8, and IL-15.")
AnnotationAssertion(rdfs:label obo:CL_0001014 "CD1a-positive Langerhans cell")
EquivalentClasses(obo:CL_0001014 ObjectIntersectionOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001447) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002025)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001014 obo:CL_0000453)

# Class: obo:CL_0001015 (CD8-alpha-low Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001015 "CD8-alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8-alpha-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001015 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000027)(PMID:19243617). They are also CD205-high, CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD285-positive (TLR5), CD286-positive (TLR6), and CD289-positive (TLR9).")
AnnotationAssertion(rdfs:label obo:CL_0001015 "CD8-alpha-low Langerhans cell")
EquivalentClasses(obo:CL_0001015 ObjectIntersectionOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001015 obo:CL_0000453)

# Class: obo:CL_0001016 (immature CD1a-positive Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001016 "Immature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001016 "Originally described in the dendritic cell ontology (DC_CL:0000028)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001016 "immature CD1a-positive Langerhans cell")
EquivalentClasses(obo:CL_0001016 ObjectIntersectionOf(obo:CL_0001014 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001016 obo:CL_0001014)

# Class: obo:CL_0001017 (mature CD1a-positive Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17850486") obo:IAO_0000115 obo:CL_0001017 "Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001017 "Originally described in the dendritic cell ontology (DC_CL:0000029)(PMID:19243617). When activated, these cells produce IL-6, IL-8, and IL-15.")
AnnotationAssertion(rdfs:label obo:CL_0001017 "mature CD1a-positive Langerhans cell")
EquivalentClasses(obo:CL_0001017 ObjectIntersectionOf(obo:CL_0001014 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001017 obo:CL_0001014)
SubClassOf(obo:CL_0001017 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001016))

# Class: obo:CL_0001018 (immature CD8-alpha-low Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001018 "Immature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:comment obo:CL_0001018 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000030)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001018 "immature CD8-alpha-low Langerhans cell")
EquivalentClasses(obo:CL_0001018 ObjectIntersectionOf(obo:CL_0001015 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001018 obo:CL_0001015)
SubClassOf(obo:CL_0001018 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001019))

# Class: obo:CL_0001019 (CD115-positive monocyte OR common dendritic progenitor)

AnnotationAssertion(rdfs:comment obo:CL_0001019 "Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001019 "CD115-positive monocyte OR common dendritic progenitor")
EquivalentClasses(obo:CL_0001019 ObjectUnionOf(obo:CL_0001022 obo:CL_0001029))
SubClassOf(obo:CL_0001019 obo:CL_0002031)

# Class: obo:CL_0001020 (mature CD8-alpha-low Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") obo:IAO_0000115 obo:CL_0001020 "Mature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001020 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000031)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001020 "mature CD8-alpha-low Langerhans cell")
EquivalentClasses(obo:CL_0001020 ObjectIntersectionOf(obo:CL_0001015 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001020 obo:CL_0001015)
SubClassOf(obo:CL_0001020 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001018))

# Class: obo:CL_0001021 (CD34-positive, CD38-positive common lymphoid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2346585") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0001021 "A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001021 "CD10-positive common lymphocyte precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001021 "CD10-positive common lymphocyte progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001021 "CD10-positive common lymphoid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001021 "These markers are associated with human common lymphoid progenitors. Originally described in the dendritic cell ontology (DC_CL:0000032)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001021 "CD34-positive, CD38-positive common lymphoid progenitor")
EquivalentClasses(obo:CL_0001021 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001021 obo:CL_0000051)
SubClassOf(obo:CL_0001021 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002043))
DisjointClasses(obo:CL_0001021 obo:CL_0001025)

# Class: obo:CL_0001022 (CD115-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17952047") obo:IAO_0000115 obo:CL_0001022 "CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive.")
AnnotationAssertion(rdfs:comment obo:CL_0001022 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000033)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001022 "CD115-positive monocyte")
EquivalentClasses(obo:CL_0001022 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001022 obo:CL_0000576)
SubClassOf(obo:CL_0001022 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002001))

# Class: obo:CL_0001023 (Kit-positive, CD34-positive common myeloid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:1261582") Annotation(oboInOwl:hasDbXref "PMID:17952047") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0001023 "A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0001023 "CD117-positive common myeloid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001023 "Markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000034)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001023 "Kit-positive, CD34-positive common myeloid progenitor")
EquivalentClasses(obo:CL_0001023 ObjectIntersectionOf(obo:CL_0001059 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0033001) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001481)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001023 obo:CL_0001059)
SubClassOf(obo:CL_0001023 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002035))
DisjointClasses(obo:CL_0001023 obo:CL_0001026)

# Class: obo:CL_0001024 (CD34-positive, CD38-negative hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:10430905") Annotation(oboInOwl:hasDbXref "PMID:11750107") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:20024907") Annotation(oboInOwl:hasDbXref "PMID:9389721") obo:IAO_0000115 obo:CL_0001024 "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001024 "CALOHA:TS-0448")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16140871") oboInOwl:hasExactSynonym obo:CL_0001024 "CD133-positive hematopoietic stem cell")
AnnotationAssertion(rdfs:comment obo:CL_0001024 "Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001024 "CD34-positive, CD38-negative hematopoietic stem cell")
EquivalentClasses(obo:CL_0001024 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001892) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001786) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001809) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001843)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001024 obo:CL_0000037)

# Class: obo:CL_0001025 (Kit-positive, Sca1-positive common lymphoid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:17952047") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0001025 "A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001025 "CD217-positive common lymphocyte precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001025 "CD217-positive common lymphocyte progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001025 "CD217-positive common lymphoid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001025 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0001025 "Kit-positive, Sca1-positive common lymphoid progenitor")
EquivalentClasses(obo:CL_0001025 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001025 obo:CL_0000051)
SubClassOf(obo:CL_0001025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000936))

# Class: obo:CL_0001026 (CD34-positive, CD38-positive common myeloid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMCID:PMC2626675") Annotation(oboInOwl:hasDbXref "PMID:16551251") obo:IAO_0000115 obo:CL_0001026 "A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative.")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0001026 "CD71-positive common myeloid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001026 "Markers are associated with human cell type. Originally described in the dendritic cell ontology (DC_CL:0000038)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001026 "CD34-positive, CD38-positive common myeloid progenitor")
EquivalentClasses(obo:CL_0001026 ObjectIntersectionOf(obo:CL_0001059 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001836) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001867) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001898) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001865)))
SubClassOf(obo:CL_0001026 obo:CL_0001059)
SubClassOf(obo:CL_0001026 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002043))

# Class: obo:CL_0001027 (CD7-negative lymphoid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") obo:IAO_0000115 obo:CL_0001027 "CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001027 "CD7-negative lymphoid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001027 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000039)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001027 "CD7-negative lymphoid progenitor cell")
EquivalentClasses(obo:CL_0001027 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001836) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001027 obo:CL_0000051)
SubClassOf(obo:CL_0001027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001021))

# Class: obo:CL_0001028 (CD7-positive lymphoid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:19491395") obo:IAO_0000115 obo:CL_0001028 "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001028 "CD7-positive lymphoid precursor")
AnnotationAssertion(rdfs:comment obo:CL_0001028 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001028 "CD7-positive lymphoid progenitor cell")
EquivalentClasses(obo:CL_0001028 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001836)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001028 obo:CL_0000051)
SubClassOf(obo:CL_0001028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001027))

# Class: obo:CL_0001029 (common dendritic progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:17922016") Annotation(oboInOwl:hasDbXref "PMID:19286519") obo:IAO_0000115 obo:CL_0001029 "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21219184") oboInOwl:hasExactSynonym obo:CL_0001029 "CDP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001029 "common dendritic precursor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21219184") oboInOwl:hasExactSynonym obo:CL_0001029 "pro-DCs")
AnnotationAssertion(rdfs:comment obo:CL_0001029 "Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001029 "common dendritic progenitor")
EquivalentClasses(obo:CL_0001029 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001029 obo:CL_0002031)
SubClassOf(obo:CL_0001029 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002009))

# Class: obo:CL_0001030 (CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor)

AnnotationAssertion(rdfs:comment obo:CL_0001030 "Originally described in the dendritic cell ontology (DC_CL:1111100)(PMID:19243617).")
AnnotationAssertion(rdfs:label obo:CL_0001030 "CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor")
EquivalentClasses(obo:CL_0001030 ObjectUnionOf(obo:CL_0001023 obo:CL_0001025))
SubClassOf(obo:CL_0001030 obo:CL_0001060)

# Class: obo:CL_0001031 (cerebellar granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mah") Annotation(oboInOwl:hasDbXref "doi:10.12688/f1000research.15021.1") Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") obo:IAO_0000115 obo:CL_0001031 "An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001031 "BTO:0004278")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") oboInOwl:hasExactSynonym obo:CL_0001031 "granule cell of the cerebellum")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") rdfs:comment obo:CL_0001031 "It has been noted in at least some mammalian species that granule cells are the most numerous cell type in the cerebellum and in the brain, with at least 99% of all cerebellar neurons being granule cells.")
AnnotationAssertion(rdfs:label obo:CL_0001031 "cerebellar granule cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_0001031 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0001031 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
EquivalentClasses(obo:CL_0001031 ObjectIntersectionOf(obo:CL_0000120 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002037)))
SubClassOf(obo:CL_0001031 obo:CL_0000679)
SubClassOf(obo:CL_0001031 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_0002362))

# Class: obo:CL_0001032 (cortical granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mah") obo:IAO_0000115 obo:CL_0001032 "Granule cell that is part of the cerebral cortex.")
AnnotationAssertion(rdfs:label obo:CL_0001032 "cortical granule cell")
EquivalentClasses(obo:CL_0001032 ObjectIntersectionOf(obo:CL_0000120 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_0001033 (hippocampal granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mah") obo:IAO_0000115 obo:CL_0001033 "Granule cell with a soma found in the hippocampus.")
AnnotationAssertion(rdfs:label obo:CL_0001033 "hippocampal granule cell")
EquivalentClasses(obo:CL_0001033 ObjectIntersectionOf(obo:CL_0000120 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002421)))

# Class: obo:CL_0001034 (cell in vitro)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0001034 "A cell that is maintained or propagated in a controlled artificial environment for use in an investigation.")
AnnotationAssertion(terms:contributor obo:CL_0001034 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0001034 "2012-01-12T09:58:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0001034 "'In vitro', translating literally to 'in glass', typically refers to a controlled, often sterile, laboratory setting where cells or other specimens are placed by some agent for the purpose of studying or manipulating them as part of some research investigation. 'In vitro' is intended to contrast with 'native',which refers to cells or other biological entities that are found in a natural setting. It describes unicellular organisms removed from a natural environement and multicellular organism cells removed from an organism, or cells derived in culture from such displaced cells.")
AnnotationAssertion(rdfs:label obo:CL_0001034 "cell in vitro")
SubClassOf(obo:CL_0001034 obo:CL_0000000)

# Class: obo:CL_0001035 (bone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0001035 "A connective tissue cell found in bone.")
AnnotationAssertion(terms:contributor obo:CL_0001035 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0001035 "2011-11-16T04:28:16Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0001035 "bone cell")
EquivalentClasses(obo:CL_0001035 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001474)))

# Class: obo:CL_0001039 (terminally differentiated osteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VSAO:curator") obo:IAO_0000115 obo:CL_0001039 "Osteoblast that is terminally differentiated, located adjacent to acellular or cellular bone tissue within periosteum, and is capable of mineralizing the matrix.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001039 "VSAO:0000116")
AnnotationAssertion(rdfs:label obo:CL_0001039 "terminally differentiated osteoblast")
SubClassOf(obo:CL_0001039 obo:CL_0000062)

# Class: obo:CL_0001040 (non-terminally differentiated osteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VSAO:curator") obo:IAO_0000115 obo:CL_0001040 "Osteoblast that is non-terminally differentiated and located in cellular bone tissue or under the periosteum in acellular bone.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001040 "VSAO:0000117")
AnnotationAssertion(rdfs:comment obo:CL_0001040 "VSAO relationship simplified OBO_REL:integral_part_of VSAO:0000118")
AnnotationAssertion(rdfs:label obo:CL_0001040 "non-terminally differentiated osteoblast")
SubClassOf(obo:CL_0001040 obo:CL_0000062)
SubClassOf(obo:CL_0001040 obo:CL_0011026)
SubClassOf(obo:CL_0001040 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002481))

# Class: obo:CL_0001041 (CD8-positive, CXCR3-positive, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:19609979") obo:IAO_0000115 obo:CL_0001041 "A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8+CXCR3+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8+CXCR3+ T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8+CXCR3+ T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8+CXCR3+ T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8+CXCR3+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3-positive, T(reg)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3-positive, Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001041 "These cells may be the human equivalent of murine CD8-positive, CD122-positive alpha-beta regulatory T cell. They are also found in the CD45RA-negative and CD62L-positive fraction.")
AnnotationAssertion(rdfs:label obo:CL_0001041 "CD8-positive, CXCR3-positive, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0001041 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032689) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042130)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001041 obo:CL_0000795)

# Class: obo:CL_0001042 (T-helper 22 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:19578368") Annotation(oboInOwl:hasDbXref "PMID:19578369") obo:IAO_0000115 obo:CL_0001042 "CD4-positive, alpha-beta T cell that produces IL-22.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "T(H)-22 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "Th22 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "Th22 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "Th22 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "Th22 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "Th22 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "helper T cell type 22")
AnnotationAssertion(rdfs:comment obo:CL_0001042 "TH22 cells are also reportedly CCR4-positive, CCR6-positive, CCR10-positive, CXCR3-negative. TH22 cells are reportedly capable of secreting IL-13.")
AnnotationAssertion(rdfs:label obo:CL_0001042 "T-helper 22 cell")
EquivalentClasses(obo:CL_0001042 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032626)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001042 obo:CL_0000492)
SubClassOf(obo:CL_0001042 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0001043 (activated CD4-positive, alpha-beta T cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001043 "A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001043 "activated CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001043 "activated CD4-positive, alpha-beta T lymphocyte, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001043 "activated CD4-positive, alpha-beta T-cell, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001043 "activated CD4-positive, alpha-beta T-lymphocyte, human")
AnnotationAssertion(rdfs:comment obo:CL_0001043 "This cell type is compatible with the HIPC Lyoplate markers for 'activated CD4+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD4+ T cells.  The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II.")
AnnotationAssertion(rdfs:label obo:CL_0001043 "activated CD4-positive, alpha-beta T cell, human")
EquivalentClasses(obo:CL_0001043 ObjectIntersectionOf(obo:CL_0000896 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001043 obo:CL_0000896)

# Class: obo:CL_0001044 (effector CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001044 "A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001044 "effector CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001044 "effector CD4-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001044 "effector CD4-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001044 "effector CD4-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001044 "This cell type is compatible with the HIPC Lyoplate markers for 'effector CD4+ T cell'.  The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy.")
AnnotationAssertion(rdfs:label obo:CL_0001044 "effector CD4-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0001044 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015)))
SubClassOf(obo:CL_0001044 obo:CL_0000911)

# Class: obo:CL_0001045 (naive CCR4-positive regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001045 "A naive regulatory T cell with the phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0001045 "naive CCR4+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001045 "naive CCR4-positive regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001045 "naive CCR4-positive regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001045 "naive CCR4-positive regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001045 "This cell type is compatible with the HIPC Lyoplate markers for 'naive CCR4+ Treg'.  The definition is valid for human; its applicability for mouse and other species is unknown.")
AnnotationAssertion(rdfs:label obo:CL_0001045 "naive CCR4-positive regulatory T cell")
EquivalentClasses(obo:CL_0001045 ObjectIntersectionOf(obo:CL_0002677 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001200)))
SubClassOf(obo:CL_0001045 obo:CL_0002677)

# Class: obo:CL_0001046 (memory CCR4-positive regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001046 "A memory regulatory T cell with phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0001046 "memory CCR4+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001046 "memory CCR4-positive regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001046 "memory CCR4-positive regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001046 "memory CCR4-positive regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001046 "This cell type is compatible with the HIPC Lyoplate markers for 'memory CCR4+ Treg'.  The definition is valid for human; its applicability for mouse and other species is unknown.")
AnnotationAssertion(rdfs:label obo:CL_0001046 "memory CCR4-positive regulatory T cell")
EquivalentClasses(obo:CL_0001046 ObjectIntersectionOf(obo:CL_0002678 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001200) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001046 obo:CL_0002678)

# Class: obo:CL_0001047 (CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001047 "A CD4-positive, CD25-positive, alpha-beta regulatory T cell with the additional phenotype CCR4-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0001047 "CCR+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001047 "CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001047 "CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001047 "CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001047 "This cell type is compatible with the HIPC Lyoplate markers for 'CCR4+ Treg'.  The definition is valid for human; its applicability for mouse and other species is unknown.")
AnnotationAssertion(rdfs:label obo:CL_0001047 "CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell")
EquivalentClasses(obo:CL_0001047 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001200)))
SubClassOf(obo:CL_0001047 obo:CL_0000792)

# Class: obo:CL_0001048 (activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001048 "A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0001048 "activated CCR4+ Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001048 "activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001048 "activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001048 "activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001048 "This cell type is compatible with the HIPC Lyoplate markers for 'activated CCR4+ Treg'.  The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II.")
AnnotationAssertion(rdfs:label obo:CL_0001048 "activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human")
EquivalentClasses(obo:CL_0001048 ObjectIntersectionOf(obo:CL_0001047 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001048 obo:CL_0001047)

# Class: obo:CL_0001049 (activated CD8-positive, alpha-beta T cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001049 "A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001049 "activated CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001049 "activated CD8-positive, alpha-beta T lymphocyte, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001049 "activated CD8-positive, alpha-beta T-cell, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001049 "activated CD8-positive, alpha-beta T-lymphocyte, human")
AnnotationAssertion(rdfs:comment obo:CL_0001049 "This cell type is compatible with the HIPC Lyoplate markers for 'activated CD8+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD8+ T cells.  The inclusion of HLA-DRA in the definition restricts this definition to human activated CD8+ T cells, as activated mouse T cells do not express MHC class II.")
AnnotationAssertion(rdfs:label obo:CL_0001049 "activated CD8-positive, alpha-beta T cell, human")
EquivalentClasses(obo:CL_0001049 ObjectIntersectionOf(obo:CL_0000906 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001049 obo:CL_0000906)

# Class: obo:CL_0001050 (effector CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001050 "A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001050 "effector CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001050 "effector CD8-positive, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001050 "effector CD8-positive, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001050 "effector CD8-positive, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001050 "This cell type is compatible with the HIPC Lyoplate markers for 'effector CD8+ T cell'.  The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy.")
AnnotationAssertion(rdfs:label obo:CL_0001050 "effector CD8-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_0001050 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402)))
SubClassOf(obo:CL_0001050 obo:CL_0000911)

# Class: obo:CL_0001051 (CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001051 "A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001051 "non-Th1/Th17 CD4+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001051 "CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001051 "CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001051 "CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001051 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell'.  Cells of this phenotype may include T-helper 2 T cells and some naive CD4+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0001051 "CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell")
EquivalentClasses(obo:CL_0001051 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207)))
SubClassOf(obo:CL_0001051 obo:CL_0000624)

# Class: obo:CL_0001052 (CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001052 "A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001052 "non-Tc1/Tc17 CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001052 "CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001052 "CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001052 "CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001052 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell'.  Cells of this phenotype may include Tc2 T cells and some naive CD8+ T cells.")
AnnotationAssertion(rdfs:label obo:CL_0001052 "CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell")
EquivalentClasses(obo:CL_0001052 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207)))
SubClassOf(obo:CL_0001052 obo:CL_0000625)

# Class: obo:CL_0001053 (IgD-negative memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001053 "A memory B cell that lacks expression of surface IgD.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0001053 "IgD- memory B cell")
AnnotationAssertion(rdfs:comment obo:CL_0001053 "This cell type is compatible with the HIPC Lyoplate markers for 'IgD- memory B cell'.  The majority of these cells are class-switched, though some are IgM-positive.")
AnnotationAssertion(rdfs:label obo:CL_0001053 "IgD-negative memory B cell")
EquivalentClasses(obo:CL_0001053 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738)))
SubClassOf(obo:CL_0001053 obo:CL_0000787)

# Class: obo:CL_0001054 (CD14-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001054 "A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasNarrowSynonym obo:CL_0001054 "monocyte")
AnnotationAssertion(rdfs:comment obo:CL_0001054 "This cell type is compatible with the HIPC Lyoplate markers for 'monocyte'. Note that while CD14 is considered a reliable marker for human monocytes, it is only expressed on approximately 85% of mouse monocytes.")
AnnotationAssertion(rdfs:label obo:CL_0001054 "CD14-positive monocyte")
EquivalentClasses(obo:CL_0001054 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889)))
SubClassOf(obo:CL_0001054 obo:CL_0000576)

# Class: obo:CL_0001055 (CD14-positive, CD16-low monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:20628149") obo:IAO_0000115 obo:CL_0001055 "An intermediate monocyte that is CD14-positive and with low amounts of CD16.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001055 "intermediate monocyte, human")
AnnotationAssertion(rdfs:comment obo:CL_0001055 "Definition is valid for human intermediate monocytes.")
AnnotationAssertion(rdfs:label obo:CL_0001055 "CD14-positive, CD16-low monocyte")
EquivalentClasses(obo:CL_0001055 ObjectIntersectionOf(obo:CL_0002393 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001483)))
SubClassOf(obo:CL_0001055 obo:CL_0002393)

# Class: obo:CL_0001056 (dendritic cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001056 "A dendritic cell with the phenotype HLA-DRA-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001056 "dendritic cell")
AnnotationAssertion(rdfs:comment obo:CL_0001056 "This cell type is compatible with the HIPC Lyoplate markers for 'dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human dendritic cells.")
AnnotationAssertion(rdfs:label obo:CL_0001056 "dendritic cell, human")
EquivalentClasses(obo:CL_0001056 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001056 obo:CL_0000451)

# Class: obo:CL_0001057 (myeloid dendritic cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001057 "A myeloid dendritic cell with the phenotype HLA-DRA-positive.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001057 "myeloid dendritic cell")
AnnotationAssertion(rdfs:comment obo:CL_0001057 "This cell type is compatible with the HIPC Lyoplate markers for 'myeloid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human myeloid dendritic cells.")
AnnotationAssertion(rdfs:label obo:CL_0001057 "myeloid dendritic cell, human")
EquivalentClasses(obo:CL_0001057 ObjectIntersectionOf(obo:CL_0000782 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001057 obo:CL_0000782)

# Class: obo:CL_0001058 (plasmacytoid dendritic cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0001058 "A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasBroadSynonym obo:CL_0001058 "plasmacytoid dendritic cell")
AnnotationAssertion(rdfs:comment obo:CL_0001058 "This cell type is compatible with the HIPC Lyoplate markers for 'plasmacytoid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human plasmacytoid dendritic cells.")
AnnotationAssertion(rdfs:label obo:CL_0001058 "plasmacytoid dendritic cell, human")
EquivalentClasses(obo:CL_0001058 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001058 obo:CL_0000784)

# Class: obo:CL_0001059 (common myeloid progenitor, CD34-positive)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasDbXref "PMCID:PMC2212039") Annotation(oboInOwl:hasDbXref "PMID:10724173") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "PMID:16647566") obo:IAO_0000115 obo:CL_0001059 "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001059 "common myeloid precursor, CD34-positive")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0001059 "CFU-GEMM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0001059 "CFU-S")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0001059 "CMP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0001059 "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0001059 "multipotential myeloid stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0001059 "myeloid stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0001059 "pluripotent stem cell (bone marrow)")
AnnotationAssertion(rdfs:comment obo:CL_0001059 "CMP are reportedly CD16-positive, CD32-positive, CD38-positive, CD45RA-negative, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.")
AnnotationAssertion(rdfs:label obo:CL_0001059 "common myeloid progenitor, CD34-positive")
EquivalentClasses(obo:CL_0001059 ObjectIntersectionOf(obo:CL_0000049 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002573) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011)))
SubClassOf(obo:CL_0001059 obo:CL_0000049)

# Class: obo:CL_0001060 (hematopoietic oligopotent progenitor cell, lineage-negative)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0001060 "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.")
AnnotationAssertion(terms:contributor obo:CL_0001060 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0001060 "2010-01-06T03:43:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0001060 "hematopoietic oligopotent progenitor cell, lineage-negative")
EquivalentClasses(obo:CL_0001060 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001401)))
SubClassOf(obo:CL_0001060 obo:CL_0002032)
SubClassOf(obo:CL_0001060 obo:CL_0008001)
SubClassOf(obo:CL_0001060 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000837))

# Class: obo:CL_0001061 (abnormal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:cg") Annotation(oboInOwl:hasDbXref "GOC:wdd") obo:IAO_0000115 obo:CL_0001061 "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models.")
AnnotationAssertion(terms:contributor obo:CL_0001061 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001061 "2017-01-30T18:53:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001061 "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913")
AnnotationAssertion(rdfs:comment obo:CL_0001061 "https://github.com/obophenotype/cell-ontology/issues/448")
AnnotationAssertion(rdfs:label obo:CL_0001061 "abnormal cell")
EquivalentClasses(obo:CL_0001061 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000460)))
SubClassOf(obo:CL_0001061 obo:CL_0000000)

# Class: obo:CL_0001062 (effector memory CD8-positive, alpha-beta T cell, terminally differentiated)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dos") Annotation(oboInOwl:hasDbXref "PMID:15032595") Annotation(oboInOwl:hasDbXref "PMID:16237082") Annotation(oboInOwl:hasDbXref "PMID:26883338") obo:IAO_0000115 obo:CL_0001062 "A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15032595") oboInOwl:hasBroadSynonym obo:CL_0001062 "TEMRA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15032595") oboInOwl:hasExactSynonym obo:CL_0001062 "CD8+ TEMRA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15032595") oboInOwl:hasExactSynonym obo:CL_0001062 "CD8-positive TEMRA")
AnnotationAssertion(rdfs:comment obo:CL_0001062 "This cell type is seen in human but not found in the mouse.")
AnnotationAssertion(rdfs:label obo:CL_0001062 "effector memory CD8-positive, alpha-beta T cell, terminally differentiated")
EquivalentClasses(obo:CL_0001062 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001017) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))
SubClassOf(obo:CL_0001062 obo:CL_0000909)
SubClassOf(obo:CL_0001062 obo:CL_4030002)
SubClassOf(obo:CL_0001062 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000913))

# Class: obo:CL_0001063 (neoplastic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:cg") Annotation(oboInOwl:hasDbXref "GOC:wdd") obo:IAO_0000115 obo:CL_0001063 "An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism.")
AnnotationAssertion(terms:contributor obo:CL_0001063 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001063 "2017-01-30T19:16:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001063 "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12922")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001063 "tumor cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001063 "tumour cell")
AnnotationAssertion(rdfs:comment obo:CL_0001063 "https://github.com/obophenotype/cell-ontology/issues/448")
AnnotationAssertion(rdfs:label obo:CL_0001063 "neoplastic cell")
EquivalentClasses(obo:CL_0001063 ObjectIntersectionOf(obo:CL_0001061 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002011)))
SubClassOf(obo:CL_0001063 obo:CL_0001061)

# Class: obo:CL_0001064 (malignant cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:cg") Annotation(oboInOwl:hasDbXref "GOC:wdd") obo:IAO_0000115 obo:CL_0001064 "A neoplastic cell that is capable of entering a surrounding tissue")
AnnotationAssertion(terms:contributor obo:CL_0001064 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001064 "2017-01-30T19:39:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001064 "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12917")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001064 "cancer cell")
AnnotationAssertion(rdfs:comment obo:CL_0001064 "https://github.com/obophenotype/cell-ontology/issues/448")
AnnotationAssertion(rdfs:label obo:CL_0001064 "malignant cell")
EquivalentClasses(obo:CL_0001064 ObjectIntersectionOf(obo:CL_0001063 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002097)))
SubClassOf(obo:CL_0001064 obo:CL_0001063)

# Class: obo:CL_0001065 (innate lymphoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:23292121") Annotation(oboInOwl:hasDbXref "PMID:23348417") obo:IAO_0000115 obo:CL_0001065 "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.")
AnnotationAssertion(terms:contributor obo:CL_0001065 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001065 "2017-01-30T20:20:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0001065 "innate lymphoid cell")
EquivalentClasses(obo:CL_0001065 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087)))

# Class: obo:CL_0001066 (erythroid progenitor cell, mammalian)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0001066 "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001066 "BTO:0004911")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0001066 "BFU-E")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0001066 "CFU-E")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001066 "blast forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001066 "burst forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001066 "colony forming unit erythroid")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0001066 "erythroid stem cell")
AnnotationAssertion(rdfs:label obo:CL_0001066 "erythroid progenitor cell, mammalian")
EquivalentClasses(obo:CL_0001066 ObjectIntersectionOf(obo:CL_0000038 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030218)))
SubClassOf(obo:CL_0001066 obo:CL_0000038)

# Class: obo:CL_0001067 (group 1 innate lymphoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:23348417") obo:IAO_0000115 obo:CL_0001067 "An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines.")
AnnotationAssertion(terms:contributor obo:CL_0001067 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001067 "2017-01-30T20:42:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0001067 "group 1 innate lymphoid cell")
EquivalentClasses(obo:CL_0001067 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609)))

# Class: obo:CL_0001068 (ILC1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:23292121") Annotation(oboInOwl:hasDbXref "PMID:23348417") obo:IAO_0000115 obo:CL_0001068 "A group 1 innate lymphoid cell that is non-cytotoxic.")
AnnotationAssertion(terms:contributor obo:CL_0001068 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001068 "2017-01-30T20:54:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0001068 "ILC1")
SubClassOf(obo:CL_0001068 obo:CL_0001067)

# Class: obo:CL_0001069 (group 2 innate lymphoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:23292121") Annotation(oboInOwl:hasDbXref "PMID:23562755") obo:IAO_0000115 obo:CL_0001069 "An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation.")
AnnotationAssertion(terms:contributor obo:CL_0001069 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001069 "2017-01-30T21:20:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001069 "ILC2")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001069 "natural helper cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001069 "nuocyte")
AnnotationAssertion(rdfs:label obo:CL_0001069 "group 2 innate lymphoid cell")
EquivalentClasses(obo:CL_0001069 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032634)))

# Class: obo:CL_0001070 (beige adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:ymb") Annotation(oboInOwl:hasDbXref "PMID:22796012") Annotation(oboInOwl:hasDbXref "PMID:25851693") obo:IAO_0000115 obo:CL_0001070 "An adipocyte that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001070 "MESH:D000069797")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "beige brown adipocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "beige fat cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "beige/brite adipocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "brite adipocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "brite cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001070 "brite fat cell")
AnnotationAssertion(rdfs:label obo:CL_0001070 "beige adipocyte")
SubClassOf(obo:CL_0001070 obo:CL_0000136)
SubClassOf(obo:CL_0001070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001347))

# Class: obo:CL_0001071 (group 3 innate lymphoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:23292121") Annotation(oboInOwl:hasDbXref "PMID:23348417") obo:IAO_0000115 obo:CL_0001071 "An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22.")
AnnotationAssertion(terms:contributor obo:CL_0001071 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001071 "2017-01-31T20:21:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001071 "ILC3")
AnnotationAssertion(rdfs:label obo:CL_0001071 "group 3 innate lymphoid cell")
EquivalentClasses(obo:CL_0001071 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003455)))

# Class: obo:CL_0001072 (CD34-negative, CD117-positive innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:30193847") Annotation(oboInOwl:hasDbXref "PMID:31201208") obo:IAO_0000115 obo:CL_0001072 "An innate lymphoid cell in the human with the phenotype CD34-negative, CD117-positive, and a precusor to NK cells, ILC2 cells, and ILC3 cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001072 "CD34-negative, CD117-positive ILC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001072 "CD34-negative, CD117-positive ILCP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001072 "CD34-negative, CD117-positive innate lymphoid cell precusor")
AnnotationAssertion(rdfs:label obo:CL_0001072 "CD34-negative, CD117-positive innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001072 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_P28906) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P10721) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0001072 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001074))

# Class: obo:CL_0001073 (CD34-negative, CD56-positive, CD117-positive innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:30193847") Annotation(oboInOwl:hasDbXref "PMID:31201208") obo:IAO_0000115 obo:CL_0001073 "An innate lymphoid cell in the human with the phenotype CD34-negative, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001073 "CD34-negative, CD56-positive, CD117-positive ILC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001073 "CD34-negative, CD56-positive, CD117-positive ILCP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001073 "CD34-negative, CD56-positive, CD117-positive innate lymphoid cell precursor")
AnnotationAssertion(rdfs:label obo:CL_0001073 "CD34-negative, CD56-positive, CD117-positive innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001073 ObjectIntersectionOf(obo:CL_0001072 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P10721) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P13591) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001074 (CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:30193847") obo:IAO_0000115 obo:CL_0001074 "An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001074 "CD34-positive, CD56-positive, CD117-positive CILP")
AnnotationAssertion(rdfs:label obo:CL_0001074 "CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human")
EquivalentClasses(obo:CL_0001074 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P10721) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P13591) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P28906) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001075 (KLRG1-positive innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:31201208") obo:IAO_0000115 obo:CL_0001075 "An innate lymphoid cell in the human with the phenotype KLRG1-positive that is a precusor for ILC2 cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001075 "KLRG1-positive ILC")
AnnotationAssertion(rdfs:label obo:CL_0001075 "KLRG1-positive innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001075 ObjectIntersectionOf(obo:CL_0001072 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_Q96E93) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001076 (NKp46-positive innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:31201208") Annotation(oboInOwl:hasDbXref "PMID:31337734") obo:IAO_0000115 obo:CL_0001076 "An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001076 "NKp46-positive ILC")
AnnotationAssertion(rdfs:label obo:CL_0001076 "NKp46-positive innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001076 ObjectIntersectionOf(obo:CL_0001074 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_O76036) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001077 (ILC1, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:31500958") obo:IAO_0000115 obo:CL_0001077 "An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001077 "innate lymphoid cell 1, human")
AnnotationAssertion(rdfs:label obo:CL_0001077 "ILC1, human")
EquivalentClasses(obo:CL_0001077 ObjectIntersectionOf(obo:CL_0001068 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_Q9UL17) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P16871) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001078 (group 3 innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:31500958") obo:IAO_0000115 obo:CL_0001078 "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001078 "ILC3, human")
AnnotationAssertion(rdfs:label obo:CL_0001078 "group 3 innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001078 ObjectIntersectionOf(obo:CL_0001071 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P16871) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001079 (NKp44-positive group 3 innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:24778151") Annotation(oboInOwl:hasDbXref "PMID:31500958") obo:IAO_0000115 obo:CL_0001079 "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-positive.")
AnnotationAssertion(rdfs:label obo:CL_0001079 "NKp44-positive group 3 innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001079 ObjectIntersectionOf(obo:CL_0001071 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_O95944) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P16871) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001080 (NKp44-negative group 3 innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:24778151") Annotation(oboInOwl:hasDbXref "PMID:31500958") obo:IAO_0000115 obo:CL_0001080 "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative.")
AnnotationAssertion(rdfs:label obo:CL_0001080 "NKp44-negative group 3 innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001080 ObjectIntersectionOf(obo:CL_0001071 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_O95944) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P16871) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001081 (group 2 innate lymphoid cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:24778151") Annotation(oboInOwl:hasDbXref "PMID:26844414") obo:IAO_0000115 obo:CL_0001081 "A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001081 "ILC2, human")
AnnotationAssertion(rdfs:label obo:CL_0001081 "group 2 innate lymphoid cell, human")
EquivalentClasses(obo:CL_0001081 ObjectIntersectionOf(obo:CL_0001069 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_P23771) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P01589) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P16871) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_Q12918) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_Q9Y5Y4) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0001082 (immature innate lymphoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0001082 "An innate lyphoid cell with an immature phenotype.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001082 "immature ILC")
AnnotationAssertion(rdfs:label obo:CL_0001082 "immature innate lymphoid cell")
EquivalentClasses(obo:CL_0001082 ObjectIntersectionOf(obo:CL_0001065 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501)))

# Class: obo:CL_0001087 (effector memory CD4-positive, alpha-beta T cell, terminally differentiated)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:17465678") Annotation(oboInOwl:hasDbXref "PMID:26883338") Annotation(oboInOwl:hasDbXref "PMID:27997758") Annotation(oboInOwl:hasDbXref "PMID:29133794") obo:IAO_0000115 obo:CL_0001087 "A CD4-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative.")
AnnotationAssertion(terms:contributor obo:CL_0001087 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(terms:date obo:CL_0001087 "2021-01-18T16:32:44Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17465678") oboInOwl:hasBroadSynonym obo:CL_0001087 "TEMRA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17465678") oboInOwl:hasExactSynonym obo:CL_0001087 "CD4+ TEMRA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17465678") oboInOwl:hasExactSynonym obo:CL_0001087 "CD4-positive TEMRA")
AnnotationAssertion(rdfs:comment obo:CL_0001087 "This cell type is seen in human but not found in the mouse.")
AnnotationAssertion(rdfs:label obo:CL_0001087 "effector memory CD4-positive, alpha-beta T cell, terminally differentiated")
EquivalentClasses(obo:CL_0001087 ObjectIntersectionOf(obo:CL_0000897 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001017) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))
SubClassOf(obo:CL_0001087 obo:CL_0000897)
SubClassOf(obo:CL_0001087 obo:CL_4030002)
SubClassOf(obo:CL_0001087 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000905))

# Class: obo:CL_0001200 (lymphocyte of B lineage, CD19-positive)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0001200 "A lymphocyte of B lineage that is CD19-positive.")
AnnotationAssertion(terms:contributor obo:CL_0001200 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(rdfs:comment obo:CL_0001200 "Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells).  Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex).")
AnnotationAssertion(rdfs:label obo:CL_0001200 "lymphocyte of B lineage, CD19-positive")
EquivalentClasses(obo:CL_0001200 ObjectIntersectionOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001002) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_40674)))
SubClassOf(obo:CL_0001200 obo:CL_0000945)

# Class: obo:CL_0001201 (B cell, CD19-positive)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0001201 "A B cell that is CD19-positive.")
AnnotationAssertion(terms:contributor obo:CL_0001201 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001201 "B lymphocyte, CD19-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001201 "B-cell, CD19-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001201 "B-lymphocyte, CD19-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001201 "CD19+ B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001201 "CD19-positive B cell")
AnnotationAssertion(rdfs:label obo:CL_0001201 "B cell, CD19-positive")
EquivalentClasses(obo:CL_0001201 ObjectIntersectionOf(obo:CL_0001200 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001002) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019724)))
SubClassOf(obo:CL_0001201 obo:CL_0000236)

# Class: obo:CL_0001202 (CD86-positive plasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:20398308") obo:IAO_0000115 obo:CL_0001202 "A plasmablast that is CD86-positive.")
AnnotationAssertion(terms:contributor obo:CL_0001202 <https://orcid.org/0000-0001-9990-8331>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0001202 "CD86-positive, CD20-negative plasmablast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001202 "CD86+ plasmablast")
AnnotationAssertion(rdfs:label obo:CL_0001202 "CD86-positive plasmablast")
EquivalentClasses(obo:CL_0001202 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001412)))
SubClassOf(obo:CL_0001202 obo:CL_0000980)

# Class: obo:CL_0001203 (CD8-positive, alpha-beta memory T cell, CD45RO-positive)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:20146720") obo:IAO_0000115 obo:CL_0001203 "A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001203 "CD8-positive, alpha-beta memory T lymphocyte, CD45RO-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001203 "CD8-positive, alpha-beta memory T-cell, CD45RO-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001203 "CD8-positive, alpha-beta memory T-lymphocyte, CD45RO-positive")
AnnotationAssertion(rdfs:label obo:CL_0001203 "CD8-positive, alpha-beta memory T cell, CD45RO-positive")
EquivalentClasses(obo:CL_0001203 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001381)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001203 obo:CL_0000909)
SubClassOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906))

# Class: obo:CL_0001204 (CD4-positive, alpha-beta memory T cell, CD45RO-positive)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0001204 "CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001204 "CD4-positive, alpha-beta memory T lymphocyte, CD45RO-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001204 "CD4-positive, alpha-beta memory T-cell, CD45RO-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001204 "CD4-positive, alpha-beta memory T-lymphocyte, CD45RO-positive")
AnnotationAssertion(rdfs:label obo:CL_0001204 "CD4-positive, alpha-beta memory T cell, CD45RO-positive")
EquivalentClasses(obo:CL_0001204 ObjectIntersectionOf(obo:CL_0000897 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001381)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001204 obo:CL_0000897)
SubClassOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0001658 (visual pigment cell (sensu Nematoda and Protostomia))

AnnotationAssertion(rdfs:label obo:CL_0001658 "visual pigment cell (sensu Nematoda and Protostomia)")
SubClassOf(obo:CL_0001658 obo:CL_0000149)
SubClassOf(obo:CL_0001658 obo:CL_0000341)

# Class: obo:CL_0002000 (Kit-positive erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002000 "An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002000 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002000 "2010-04-26T10:14:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002000 "c- Kit-positive erythroid progenitor cell")
AnnotationAssertion(rdfs:comment obo:CL_0002000 "Markers found on mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002000 "Kit-positive erythroid progenitor cell")
EquivalentClasses(obo:CL_0002000 ObjectIntersectionOf(obo:CL_0001066 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0033001) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001833) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009127) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001345) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002000 obo:CL_0001066)
SubClassOf(obo:CL_0002000 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002006))

# Class: obo:CL_0002001 (CD34-positive, CD38-positive granulocyte monocyte progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12615892") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002001 "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002001 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002001 "2010-01-13T03:19:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002001 "Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population.")
AnnotationAssertion(rdfs:label obo:CL_0002001 "CD34-positive, CD38-positive granulocyte monocyte progenitor")
EquivalentClasses(obo:CL_0002001 ObjectIntersectionOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002001 obo:CL_0000557)
SubClassOf(obo:CL_0002001 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001026))

# Class: obo:CL_0002002 (Kit-positive granulocyte monocyte progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12615892") Annotation(oboInOwl:hasDbXref "PMID:16322423") Annotation(oboInOwl:hasDbXref "PMID:19022770") Annotation(oboInOwl:hasDbXref "PMID:19273628") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002002 "A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002002 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002002 "2010-01-13T03:19:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002002 "Markers are found on mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002002 "Kit-positive granulocyte monocyte progenitor")
EquivalentClasses(obo:CL_0002002 ObjectIntersectionOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001206) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001843) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0033001) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001479)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002002 obo:CL_0000557)
SubClassOf(obo:CL_0002002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001023))

# Class: obo:CL_0002003 (CD34-positive, GlyA-negative erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19621348") obo:IAO_0000115 obo:CL_0002003 "An erythroid progenitor cell that is CD34-positive and is GlyA-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002003 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002003 "2010-04-26T10:14:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002003 "FMA:83517")
AnnotationAssertion(rdfs:comment obo:CL_0002003 "Cell markers associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002003 "CD34-positive, GlyA-negative erythroid progenitor cell")
EquivalentClasses(obo:CL_0002003 ObjectIntersectionOf(obo:CL_0001066 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002003 obo:CL_0001066)
SubClassOf(obo:CL_0002003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002005))

# Class: obo:CL_0002004 (CD34-negative, GlyA-negative proerythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19621348") obo:IAO_0000115 obo:CL_0002004 "A proerythoblast that is CD34-negative and GlyA-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002004 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002004 "2010-04-26T10:31:50Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002004 "Cell surface markers are associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002004 "CD34-negative, GlyA-negative proerythroblast")
EquivalentClasses(obo:CL_0002004 ObjectIntersectionOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002004 obo:CL_0000547)
SubClassOf(obo:CL_0002004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002003))

# Class: obo:CL_0002005 (CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12615892") Annotation(oboInOwl:hasDbXref "PMID:190227700") obo:IAO_0000115 obo:CL_0002005 "A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002005 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002005 "2010-01-13T03:43:10Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002005 "Markers are associated with human cell type.")
AnnotationAssertion(rdfs:label obo:CL_0002005 "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell")
EquivalentClasses(obo:CL_0002005 ObjectIntersectionOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002005 obo:CL_0000050)

# Class: obo:CL_0002006 (Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12615892") Annotation(oboInOwl:hasDbXref "PMID:19022770") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002006 "A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low.")
AnnotationAssertion(terms:contributor obo:CL_0002006 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002006 "2010-01-13T03:43:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002006 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002006 "Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell")
EquivalentClasses(obo:CL_0002006 ObjectIntersectionOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001479) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001843) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0033001)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002006 obo:CL_0000050)

# Class: obo:CL_0002007 (Kit-low, CD34-positive eosinophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582345") obo:IAO_0000115 obo:CL_0002007 "A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell.")
AnnotationAssertion(terms:contributor obo:CL_0002007 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002007 "2010-01-14T03:25:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002007 "Markers are found on mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002007 "Kit-low, CD34-positive eosinophil progenitor cell")
EquivalentClasses(obo:CL_0002007 ObjectIntersectionOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002007 obo:CL_0000611)
SubClassOf(obo:CL_0002007 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002002))

# Class: obo:CL_0002008 (CD34-positive, CD38-positive eosinophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC2626675") obo:IAO_0000115 obo:CL_0002008 "A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell.")
AnnotationAssertion(terms:contributor obo:CL_0002008 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002008 "2010-01-14T03:25:17Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002008 "Markers are associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002008 "CD34-positive, CD38-positive eosinophil progenitor cell")
EquivalentClasses(obo:CL_0002008 ObjectIntersectionOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002008 obo:CL_0000611)
SubClassOf(obo:CL_0002008 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002001))

# Class: obo:CL_0002009 (macrophage dendritic cell progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19273628") obo:IAO_0000115 obo:CL_0002009 "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.")
AnnotationAssertion(terms:contributor obo:CL_0002009 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002009 "2010-01-19T02:51:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002009 "MDP")
AnnotationAssertion(rdfs:label obo:CL_0002009 "macrophage dendritic cell progenitor")
EquivalentClasses(obo:CL_0002009 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002009 obo:CL_0002032)
SubClassOf(obo:CL_0002009 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557))

# Class: obo:CL_0002010 (pre-conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002010 "A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha.")
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002010 "2010-01-19T03:39:30Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002010 "pre-conventional dendritic cell")
EquivalentClasses(obo:CL_0002010 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001968) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002010 obo:CL_0002031)
SubClassOf(obo:CL_0002010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029))

# Class: obo:CL_0002011 (Kit-positive macrophage dendritic cell progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19273628") obo:IAO_0000115 obo:CL_0002011 "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002011 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002011 "2010-01-26T02:43:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002011 "murine MDP")
AnnotationAssertion(rdfs:comment obo:CL_0002011 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002011 "Kit-positive macrophage dendritic cell progenitor")
EquivalentClasses(obo:CL_0002011 ObjectIntersectionOf(obo:CL_0002009 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001206) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002011 obo:CL_0002009)
SubClassOf(obo:CL_0002011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002002))

# Class: obo:CL_0002012 (Kit-low proerythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") obo:IAO_0000115 obo:CL_0002012 "A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002012 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002012 "2010-04-26T10:31:56Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002012 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002012 "Kit-low proerythroblast")
EquivalentClasses(obo:CL_0002012 ObjectIntersectionOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002012 obo:CL_0000547)
SubClassOf(obo:CL_0002012 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002000))

# Class: obo:CL_0002013 (GlyA-positive basophilic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1638021") obo:IAO_0000115 obo:CL_0002013 "A basophilic erythroblast that is GlyA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002013 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002013 "2010-04-26T10:41:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002013 "Markers are associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002013 "GlyA-positive basophilic erythroblast")
EquivalentClasses(obo:CL_0002013 ObjectIntersectionOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002013 obo:CL_0000549)
SubClassOf(obo:CL_0002013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002004))

# Class: obo:CL_0002014 (Kit-negative, Ly-76 high basophilic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") obo:IAO_0000115 obo:CL_0002014 "A basophilic erythroblast that is Lyg 76-high and is Kit-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002014 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002014 "2010-04-26T10:41:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002014 "Cell surface markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002014 "Kit-negative, Ly-76 high basophilic erythroblast")
EquivalentClasses(obo:CL_0002014 ObjectIntersectionOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002014 obo:CL_0000549)
SubClassOf(obo:CL_0002014 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002012))

# Class: obo:CL_0002015 (Kit-negative, Ly-76 high polychromatophilic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") obo:IAO_0000115 obo:CL_0002015 "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002015 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002015 "2010-04-26T10:53:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002015 "late basophilic and polychromatophilic erythroblast")
AnnotationAssertion(rdfs:label obo:CL_0002015 "Kit-negative, Ly-76 high polychromatophilic erythroblast")
EquivalentClasses(obo:CL_0002015 ObjectIntersectionOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002015 obo:CL_0000550)
SubClassOf(obo:CL_0002015 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002014))

# Class: obo:CL_0002016 (CD71-low, GlyA-positive polychromatic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1638021") obo:IAO_0000115 obo:CL_0002016 "A polychromatiic erythroblast that is Gly-A-positive and CD71-low.")
AnnotationAssertion(terms:contributor obo:CL_0002016 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002016 "2010-04-26T10:53:16Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002016 "Cell surface markers are associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002016 "CD71-low, GlyA-positive polychromatic erythroblast")
EquivalentClasses(obo:CL_0002016 ObjectIntersectionOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001945)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002016 obo:CL_0000550)
SubClassOf(obo:CL_0002016 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002013))

# Class: obo:CL_0002017 (Kit-negative, Ly-76 high orthochromatophilic erythroblasts)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") obo:IAO_0000115 obo:CL_0002017 "An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002017 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002017 "2010-04-26T11:04:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002017 "Cell surface markers associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002017 "Kit-negative, Ly-76 high orthochromatophilic erythroblasts")
EquivalentClasses(obo:CL_0002017 ObjectIntersectionOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001945)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002017 obo:CL_0000552)
SubClassOf(obo:CL_0002017 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002015))

# Class: obo:CL_0002018 (CD71-negative, GlyA-positive orthochromatic erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1638021") obo:IAO_0000115 obo:CL_0002018 "An erythroblast that is GlyA-positive and CD71-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002018 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002018 "2010-04-26T11:04:21Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002018 "Markers associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002018 "CD71-negative, GlyA-positive orthochromatic erythroblast")
EquivalentClasses(obo:CL_0002018 ObjectIntersectionOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002018 obo:CL_0000552)
SubClassOf(obo:CL_0002018 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002016))

# Class: obo:CL_0002019 (Ly-76 high reticulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18539294") obo:IAO_0000115 obo:CL_0002019 "A reticulocyte that is Ly76-high and is Kit-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002019 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002019 "2010-04-26T11:37:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002019 "Marker associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002019 "Ly-76 high reticulocyte")
EquivalentClasses(obo:CL_0002019 ObjectIntersectionOf(obo:CL_0002422 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002019 obo:CL_0002422)
SubClassOf(obo:CL_0002019 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002017))

# Class: obo:CL_0002020 (GlyA-positive reticulocytes)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1638021") obo:IAO_0000115 obo:CL_0002020 "A reticulocyte that is GlyA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002020 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002020 "2010-04-26T11:48:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002020 "Markers is associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002020 "GlyA-positive reticulocytes")
EquivalentClasses(obo:CL_0002020 ObjectIntersectionOf(obo:CL_0002422 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002020 obo:CL_0002422)
SubClassOf(obo:CL_0002020 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002018))

# Class: obo:CL_0002021 (GlyA-positive erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20134094") obo:IAO_0000115 obo:CL_0002021 "An enucleate erythrocyte that is GlyA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002021 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002021 "2010-04-26T11:51:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002021 "Marker is associated with human cell types.")
AnnotationAssertion(rdfs:label obo:CL_0002021 "GlyA-positive erythrocyte")
EquivalentClasses(obo:CL_0002021 ObjectIntersectionOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002021 obo:CL_0000595)
SubClassOf(obo:CL_0002021 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002020))

# Class: obo:CL_0002022 (Ly-76 high positive erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19805084") obo:IAO_0000115 obo:CL_0002022 "An enucleate erythrocyte that is Lyg-76-high.")
AnnotationAssertion(terms:contributor obo:CL_0002022 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002022 "2010-04-26T11:51:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002022 "Marker is associated with mouse cell types.")
AnnotationAssertion(rdfs:label obo:CL_0002022 "Ly-76 high positive erythrocyte")
EquivalentClasses(obo:CL_0002022 ObjectIntersectionOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002022 obo:CL_0000595)
SubClassOf(obo:CL_0002022 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002019))

# Class: obo:CL_0002023 (CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15232614") obo:IAO_0000115 obo:CL_0002023 "A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface.")
AnnotationAssertion(terms:contributor obo:CL_0002023 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002023 "2010-04-26T02:39:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002023 "Markers are associated with human cell type.")
AnnotationAssertion(rdfs:label obo:CL_0002023 "CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell")
EquivalentClasses(obo:CL_0002023 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002023 obo:CL_0000553)
SubClassOf(obo:CL_0002023 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002025))

# Class: obo:CL_0002024 (Kit-positive megakaryocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16951553") obo:IAO_0000115 obo:CL_0002024 "A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low.")
AnnotationAssertion(terms:contributor obo:CL_0002024 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002024 "2010-04-26T02:39:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002024 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002024 "Kit-positive megakaryocyte progenitor cell")
EquivalentClasses(obo:CL_0002024 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001833) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001479) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001483)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002024 obo:CL_0000553)
SubClassOf(obo:CL_0002024 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002006))

# Class: obo:CL_0002025 (CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15232614") obo:IAO_0000115 obo:CL_0002025 "A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002025 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002025 "2010-04-26T03:52:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002025 "Markers are commonly associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002025 "CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell")
EquivalentClasses(obo:CL_0002025 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002025 obo:CL_0000553)
SubClassOf(obo:CL_0002025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002005))

# Class: obo:CL_0002026 (CD34-negative, CD41-positive, CD42-positive megakaryocyte cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15232614") obo:IAO_0000115 obo:CL_0002026 "A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002026 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002026 "2010-04-26T03:59:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002026 "Markers are commonly associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002026 "CD34-negative, CD41-positive, CD42-positive megakaryocyte cell")
EquivalentClasses(obo:CL_0002026 ObjectIntersectionOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002026 obo:CL_0000556)
SubClassOf(obo:CL_0002026 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002023))

# Class: obo:CL_0002027 (CD9-positive, CD41-positive megakaryocyte cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002027 "A megakaryocyte cell with is CD9-positive and CD41-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002027 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002027 "2010-04-27T10:39:07Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002027 "Markers are commonly associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002027 "CD9-positive, CD41-positive megakaryocyte cell")
EquivalentClasses(obo:CL_0002027 ObjectIntersectionOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002027 obo:CL_0000556)
SubClassOf(obo:CL_0002027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002024))

# Class: obo:CL_0002028 (basophil mast progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") obo:IAO_0000115 obo:CL_0002028 "A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa")
AnnotationAssertion(terms:contributor obo:CL_0002028 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002028 "2010-04-27T12:46:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002028 "BMCP")
AnnotationAssertion(rdfs:comment obo:CL_0002028 "There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low.")
AnnotationAssertion(rdfs:label obo:CL_0002028 "basophil mast progenitor cell")
EquivalentClasses(obo:CL_0002028 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000007431) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000016401) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060374)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002028 obo:CL_0000839)
SubClassOf(obo:CL_0002028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557))

# Class: obo:CL_0002029 (Fc-epsilon RIalpha-low mast cell progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") obo:IAO_0000115 obo:CL_0002029 "A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low.")
AnnotationAssertion(terms:contributor obo:CL_0002029 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002029 "2010-04-27T01:22:19Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002029 "Fc-epsilon RIalpha-low mast cell progenitor")
EquivalentClasses(obo:CL_0002029 ObjectIntersectionOf(obo:CL_0000831 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009143) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000007431)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002029 obo:CL_0000831)
SubClassOf(obo:CL_0002029 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002044))

# Class: obo:CL_0002030 (Fc-epsilon RIalpha-high basophil progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC1312421") obo:IAO_0000115 obo:CL_0002030 "A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high.")
AnnotationAssertion(terms:contributor obo:CL_0002030 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002030 "2010-04-27T01:22:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002030 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002030 "Fc-epsilon RIalpha-high basophil progenitor cell")
EquivalentClasses(obo:CL_0002030 ObjectIntersectionOf(obo:CL_0000613 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002030 obo:CL_0000613)
SubClassOf(obo:CL_0002030 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002044))

# Class: obo:CL_0002031 (hematopoietic lineage restricted progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002031 "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.")
AnnotationAssertion(terms:contributor obo:CL_0002031 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002031 "2010-01-06T03:43:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002031 "hematopoietic lineage restricted progenitor cell")
EquivalentClasses(obo:CL_0002031 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001400)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002031 obo:CL_0000988)
SubClassOf(obo:CL_0002031 obo:CL_0008001)
SubClassOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002032))
DisjointClasses(obo:CL_0002031 obo:CL_0002032)

# Class: obo:CL_0002032 (hematopoietic oligopotent progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0002032 "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities.")
AnnotationAssertion(terms:contributor obo:CL_0002032 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002032 "2010-01-06T03:43:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002032 "This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell.  For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).")
AnnotationAssertion(rdfs:label obo:CL_0002032 "hematopoietic oligopotent progenitor cell")
EquivalentClasses(obo:CL_0002032 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001401)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002032 obo:CL_0000988)
SubClassOf(obo:CL_0002032 obo:CL_0008001)
SubClassOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000837))

# Class: obo:CL_0002033 (short term hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15572596") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002033 "A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002033 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002033 "2010-01-08T09:19:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002033 "ST stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002033 "ST-HSC")
AnnotationAssertion(rdfs:comment obo:CL_0002033 "Markers are associated with mouse cells. These cells are also reportedly CD11b-low and CD90-low.")
AnnotationAssertion(rdfs:label obo:CL_0002033 "short term hematopoietic stem cell")
EquivalentClasses(obo:CL_0002033 ObjectIntersectionOf(obo:CL_0001008 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002033 obo:CL_0001008)
SubClassOf(obo:CL_0002033 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002034))

# Class: obo:CL_0002034 (long term hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15572596") Annotation(oboInOwl:hasDbXref "PMID:17582345") obo:IAO_0000115 obo:CL_0002034 "A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002034 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002034 "2010-01-08T09:19:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002034 "LT stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002034 "LT-HSC")
AnnotationAssertion(rdfs:comment obo:CL_0002034 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002034 "long term hematopoietic stem cell")
EquivalentClasses(obo:CL_0002034 ObjectIntersectionOf(obo:CL_0001008 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001843)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002034 obo:CL_0001008)

# Class: obo:CL_0002035 (Slamf1-negative multipotent progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002035 "A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002035 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002035 "2010-01-08T11:16:33Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002035 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002035 "Slamf1-negative multipotent progenitor cell")
EquivalentClasses(obo:CL_0002035 ObjectIntersectionOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001833) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002035 obo:CL_0000837)
SubClassOf(obo:CL_0002035 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002036))

# Class: obo:CL_0002036 (Slamf1-positive multipotent progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002036 "A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002036 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002036 "2010-01-08T11:16:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002036 "KSL cell")
AnnotationAssertion(rdfs:comment obo:CL_0002036 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002036 "Slamf1-positive multipotent progenitor cell")
EquivalentClasses(obo:CL_0002036 ObjectIntersectionOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002036 obo:CL_0000837)
SubClassOf(obo:CL_0002036 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002033))
DisjointClasses(obo:CL_0002036 obo:CL_0002043)

# Class: obo:CL_0002037 (CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16048545") obo:IAO_0000115 obo:CL_0002037 "Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002037 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002037 "2009-10-20T02:20:43Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16048545") oboInOwl:hasExactSynonym obo:CL_0002037 "memory alpha beta IEL")
AnnotationAssertion(rdfs:label obo:CL_0002037 "CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell")
EquivalentClasses(obo:CL_0002037 ObjectIntersectionOf(obo:CL_0000793 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001083) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001839)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002037 obo:CL_0000793)

# Class: obo:CL_0002038 (T follicular helper cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19855402") Annotation(oboInOwl:hasDbXref "PMID:20107805") Annotation(oboInOwl:hasDbXref "PMID:22043829") obo:IAO_0000115 obo:CL_0002038 "A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production.")
AnnotationAssertion(terms:contributor obo:CL_0002038 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002038 "2009-10-29T04:01:27Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20207847") oboInOwl:hasExactSynonym obo:CL_0002038 "T(FH)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20107805") Annotation(oboInOwl:hasDbXref "PMID:20383172") oboInOwl:hasExactSynonym obo:CL_0002038 "Tfh")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22043829") oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular B helper T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20107805") Annotation(oboInOwl:hasDbXref "PMID:21914188") oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular T cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular T-cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22552227") oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular T-helper cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22649468") oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular helper T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22508770") oboInOwl:hasRelatedSynonym obo:CL_0002038 "follicular helper T-cell")
AnnotationAssertion(rdfs:label obo:CL_0002038 "T follicular helper cell")
EquivalentClasses(obo:CL_0002038 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003450) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001209) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001860) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001919) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002639) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045830)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002038 obo:CL_0000492)
SubClassOf(obo:CL_0002038 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))

# Class: obo:CL_0002039 (immature NK T cell stage I, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16087715") Annotation(oboInOwl:hasDbXref "PMID:17589542") Annotation(oboInOwl:hasDbXref "PMID:19423665") Annotation(oboInOwl:hasDbXref "PMID:26802287") Annotation(oboInOwl:hasDbXref "PMID:38440725") obo:IAO_0000115 obo:CL_0002039 "A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell.")
AnnotationAssertion(terms:contributor obo:CL_0002039 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002039 "2009-10-29T04:09:16Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17589542") rdfs:comment obo:CL_0002039 "The immature NK T cell stage” (I–IV) represents mouse-specific stages used to define iNKT cell development. The immature NK T cells in humans typically exhibit a CD161low; CD4+ phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0002039 "immature NK T cell stage I, mouse")
EquivalentClasses(obo:CL_0002039 ObjectIntersectionOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002039 obo:CL_0000914)
SubClassOf(obo:CL_0002039 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))

# Class: obo:CL_0002040 (immature NK T cell stage II, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16087715") Annotation(oboInOwl:hasDbXref "PMID:17589542") Annotation(oboInOwl:hasDbXref "PMID:19423665") Annotation(oboInOwl:hasDbXref "PMID:26802287") Annotation(oboInOwl:hasDbXref "PMID:38440725") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002040 "A CD24-low, CD44-negative, NK1.1-negative NK T cell.")
AnnotationAssertion(terms:contributor obo:CL_0002040 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002040 "2009-10-29T04:13:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002040 "NKT.44-NK1.1-.Th")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17589542") rdfs:comment obo:CL_0002040 "NKT.44-NK1.1-.Th was assigned as an exact synonym based on sorting strategy displayed at immgene.org. The immature NK T cell stage” (I–IV) represents mouse-specific stages used to define iNKT cell development. The immature NK T cells in humans typically exhibit a CD161low; CD4+ phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0002040 "immature NK T cell stage II, mouse")
EquivalentClasses(obo:CL_0002040 ObjectIntersectionOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002040 obo:CL_0000914)
SubClassOf(obo:CL_0002040 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002039))

# Class: obo:CL_0002041 (immature NK T cell stage III, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16087715") Annotation(oboInOwl:hasDbXref "PMID:17589542") Annotation(oboInOwl:hasDbXref "PMID:19423665") Annotation(oboInOwl:hasDbXref "PMID:26802287") Annotation(oboInOwl:hasDbXref "PMID:38440725") obo:IAO_0000115 obo:CL_0002041 "A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell.")
AnnotationAssertion(terms:contributor obo:CL_0002041 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002041 "2009-10-29T04:14:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002041 "NKT.44+.NK1.1-.Th")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17589542") rdfs:comment obo:CL_0002041 "The immature NK T cell stage” (I–IV) represents mouse-specific stages used to define iNKT cell development. The immature NK T cells in humans typically exhibit a CD161low; CD4+ phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0002041 "immature NK T cell stage III, mouse")
EquivalentClasses(obo:CL_0002041 ObjectIntersectionOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001008) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002041 obo:CL_0000914)
SubClassOf(obo:CL_0002041 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002040))

# Class: obo:CL_0002042 (immature NK T cell stage IV, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16087715") Annotation(oboInOwl:hasDbXref "PMID:17589542") Annotation(oboInOwl:hasDbXref "PMID:19423665") Annotation(oboInOwl:hasDbXref "PMID:26802287") Annotation(oboInOwl:hasDbXref "PMID:38440725") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002042 "A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell.")
AnnotationAssertion(terms:contributor obo:CL_0002042 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002042 "2009-10-29T04:17:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002042 "NKT.44+.NK1.1-.Th")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17589542") rdfs:comment obo:CL_0002042 "The immature NK T cell stage” (I–IV) represents mouse-specific stages used to define iNKT cell development. The immature NK T cells in humans typically exhibit a CD161low; CD4+ phenotype.")
AnnotationAssertion(rdfs:label obo:CL_0002042 "immature NK T cell stage IV, mouse")
EquivalentClasses(obo:CL_0002042 ObjectIntersectionOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001008) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002042 obo:CL_0000914)
SubClassOf(obo:CL_0002042 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002041))

# Class: obo:CL_0002043 (CD34-positive, CD38-negative multipotent progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18371405") Annotation(oboInOwl:hasDbXref "PMID:19022770") obo:IAO_0000115 obo:CL_0002043 "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002043 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002043 "2010-01-12T11:14:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002043 "Cell markers are associated with human hematopoietic multipotent progenitor cells.")
AnnotationAssertion(rdfs:label obo:CL_0002043 "CD34-positive, CD38-negative multipotent progenitor cell")
EquivalentClasses(obo:CL_0002043 ObjectIntersectionOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001843) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002043 obo:CL_0000837)
SubClassOf(obo:CL_0002043 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001024))

# Class: obo:CL_0002044 (Kit-positive, integrin beta7-high basophil mast progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002044 "A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002044 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002044 "2010-04-27T01:22:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002044 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002044 "Kit-positive, integrin beta7-high basophil mast progenitor cell")
EquivalentClasses(obo:CL_0002044 ObjectIntersectionOf(obo:CL_0002028 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001479) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000009143)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002044 obo:CL_0002028)

# Class: obo:CL_0002045 (fraction A pre-pro B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12633665") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:37442242") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002045 "A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002045 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002045 "2010-04-28T10:50:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002045 "fraction A")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002045 "pre pro B cell")
AnnotationAssertion(rdfs:comment obo:CL_0002045 "Markers associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002045 "fraction A pre-pro B cell")
EquivalentClasses(obo:CL_0002045 ObjectIntersectionOf(obo:CL_0000826 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002039) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002980) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002045 obo:CL_0000826)

# Class: obo:CL_0002046 (early pro-B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0002046 "A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage.")
AnnotationAssertion(terms:contributor obo:CL_0002046 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002046 "2010-04-28T11:19:11Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002046 "Markers are commonly associated with human cells. These cells are also reportedly CD21-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002046 "early pro-B cell")
EquivalentClasses(obo:CL_0002046 ObjectIntersectionOf(obo:CL_0000826 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0071707) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001288) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001898)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002046 obo:CL_0000826)

# Class: obo:CL_0002047 (fraction B precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:37442242") obo:IAO_0000115 obo:CL_0002047 "A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002047 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002047 "2010-04-28T11:56:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002047 "Fr. B")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002047 "Fraction B")
AnnotationAssertion(rdfs:comment obo:CL_0002047 "Markers are commonly associated with mouse cells. These cells are also reportedly RAG1-positive and RAG2-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002047 "fraction B precursor B cell")
EquivalentClasses(obo:CL_0002047 ObjectIntersectionOf(obo:CL_0002400 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002039) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002047 obo:CL_0002400)
SubClassOf(obo:CL_0002047 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002045))

# Class: obo:CL_0002048 (late pro-B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0002048 "A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002048 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002048 "2010-04-28T12:06:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002048 "Late pro-B cells are also reportedly CD10-positive, CD20-negative, CD21-negative, and TdT-positive. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002048 "late pro-B cell")
EquivalentClasses(obo:CL_0002048 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001288) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001002)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002048 obo:CL_0000817)
SubClassOf(obo:CL_0002048 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002046))

# Class: obo:CL_0002049 (fraction C precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:37442242") obo:IAO_0000115 obo:CL_0002049 "A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain.")
AnnotationAssertion(terms:contributor obo:CL_0002049 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002049 "2010-04-28T02:04:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002049 "Fraction C")
AnnotationAssertion(rdfs:label obo:CL_0002049 "fraction C precursor B cell")
EquivalentClasses(obo:CL_0002049 ObjectIntersectionOf(obo:CL_0002400 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001858) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001859) ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071707) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002039) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000003457) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000003460)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002049 obo:CL_0002400)
SubClassOf(obo:CL_0002049 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002047))

# Class: obo:CL_0002050 (fraction C' precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:37442242") obo:IAO_0000115 obo:CL_0002050 "A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002050 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002050 "2010-04-28T02:13:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002050 "Fr. C'")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002050 "Fraction C-prime")
AnnotationAssertion(rdfs:label obo:CL_0002050 "fraction C' precursor B cell")
EquivalentClasses(obo:CL_0002050 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002039) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002050 obo:CL_0000817)
SubClassOf(obo:CL_0002050 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002049))

# Class: obo:CL_0002051 (CD38-high pre-BCR positive cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0002051 "A pre-BCR positive B cell that is CD38-high.")
AnnotationAssertion(terms:contributor obo:CL_0002051 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002051 "2010-04-28T02:27:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002051 "large pre-B cell type I")
AnnotationAssertion(rdfs:comment obo:CL_0002051 "Markers are associated with human cells.")
AnnotationAssertion(rdfs:label obo:CL_0002051 "CD38-high pre-BCR positive cell")
EquivalentClasses(obo:CL_0002051 ObjectIntersectionOf(obo:CL_0000952 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001288) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002051 obo:CL_0000952)
SubClassOf(obo:CL_0002051 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002048))

# Class: obo:CL_0002052 (fraction D precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:37442242") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002052 "A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002052 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002052 "2010-04-28T02:55:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002052 "Fr. D")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002052 "fraction D pre-B cell")
AnnotationAssertion(rdfs:comment obo:CL_0002052 "Fraction D precursor B cells are also reportedly CD24-positive and sIgD-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002052 "fraction D precursor B cell")
EquivalentClasses(obo:CL_0002052 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071708) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001002) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002039) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001879)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002052 obo:CL_0000817)
SubClassOf(obo:CL_0002052 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002050))

# Class: obo:CL_0002053 (CD22-positive, CD38-low small pre-B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0002053 "A small pre-B cell that is CD22-positive and CD38-low.")
AnnotationAssertion(terms:contributor obo:CL_0002053 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002053 "2010-04-28T03:04:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002053 "small pre-B cell")
AnnotationAssertion(rdfs:comment obo:CL_0002053 "Markers are associated with human cell. RAG expression maybe diminishing.")
AnnotationAssertion(rdfs:label obo:CL_0002053 "CD22-positive, CD38-low small pre-B cell")
EquivalentClasses(obo:CL_0002053 ObjectIntersectionOf(obo:CL_0000954 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001288) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002053 obo:CL_0000954)
SubClassOf(obo:CL_0002053 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002051))

# Class: obo:CL_0002054 (fraction E immature B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ak") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:18432934") Annotation(oboInOwl:hasDbXref "PMID:37442242") obo:IAO_0000115 obo:CL_0002054 "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002054 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002054 "2010-04-28T03:13:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002054 "Markers associated with mouse cells. These cells are also reportedly sIgD-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002054 "fraction E immature B cell")
EquivalentClasses(obo:CL_0002054 ObjectIntersectionOf(obo:CL_0000816 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001002) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001879)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002054 obo:CL_0000816)
SubClassOf(obo:CL_0002054 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002052))

# Class: obo:CL_0002055 (CD38-negative immature B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18432934") obo:IAO_0000115 obo:CL_0002055 "An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high.")
AnnotationAssertion(terms:contributor obo:CL_0002055 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002055 "2010-04-28T03:19:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002055 "Markers are associated with human cell type.")
AnnotationAssertion(rdfs:label obo:CL_0002055 "CD38-negative immature B cell")
EquivalentClasses(obo:CL_0002055 ObjectIntersectionOf(obo:CL_0000816 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001288) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001898)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002055 obo:CL_0000816)
SubClassOf(obo:CL_0002055 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002053))

# Class: obo:CL_0002056 (fraction F mature B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17582343") Annotation(oboInOwl:hasDbXref "PMID:37442242") obo:IAO_0000115 obo:CL_0002056 "A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.")
AnnotationAssertion(terms:contributor obo:CL_0002056 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002056 "2010-04-30T03:01:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002056 "fraction F mature B cell")
EquivalentClasses(obo:CL_0002056 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002056 obo:CL_0000785)
SubClassOf(obo:CL_0002056 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002054))

# Class: obo:CL_0002057 (CD14-positive, CD16-negative classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15615263") Annotation(oboInOwl:hasDbXref "PMID:1706877") Annotation(oboInOwl:hasDbXref "PMID:19689341") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0002057 "A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002057 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002057 "2010-06-05T08:25:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0002057 "CD16- monocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002057 "CD16-negative monocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002057 "This cell type is compatible with the HIPC Lyoplate markers for 'CD16- monocyte'. The markers used in the definition are associated with human monocytes.")
AnnotationAssertion(rdfs:label obo:CL_0002057 "CD14-positive, CD16-negative classical monocyte")
EquivalentClasses(obo:CL_0002057 ObjectIntersectionOf(obo:CL_0000860 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001465) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002057 obo:CL_0000860)

# Class: obo:CL_0002058 (Gr1-low non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:8890901") obo:IAO_0000115 obo:CL_0002058 "A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002058 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002058 "2010-06-05T08:25:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002058 "Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product. Also, this cell-type is sometimes described as being Gr1-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002058 "Gr1-low non-classical monocyte")
EquivalentClasses(obo:CL_0002058 ObjectIntersectionOf(obo:CL_0000875 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001206) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001199) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002980)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002058 obo:CL_0000875)
SubClassOf(obo:CL_0002058 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002398))

# Class: obo:CL_0002059 (CD8-alpha-positive thymic conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19273629") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002059 "A conventional thymic dendritic cell that is CD8-alpha-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002059 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002059 "2010-06-07T02:48:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002059 "CD8alpha-alpha-positive thymic conventional dendritic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002059 "DC.8+.Th")
AnnotationAssertion(rdfs:label obo:CL_0002059 "CD8-alpha-positive thymic conventional dendritic cell")
EquivalentClasses(obo:CL_0002059 ObjectIntersectionOf(obo:CL_0000941 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002059 obo:CL_0000941)

# Class: obo:CL_0002060 (melanophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20479296") Annotation(oboInOwl:hasDbXref "PMID:2943821") obo:IAO_0000115 obo:CL_0002060 "A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes.")
AnnotationAssertion(terms:contributor obo:CL_0002060 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002060 "2010-06-22T10:46:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002060 "melanophage")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002060 obo:CL_0000864)
SubClassOf(obo:CL_0002060 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002097))

# Class: obo:CL_0002061 (T-helper 9 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18931678") Annotation(oboInOwl:hasDbXref "PMID:19604299") Annotation(oboInOwl:hasDbXref "PMID:20154671") obo:IAO_0000115 obo:CL_0002061 "A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and IL-4. Th2 cytokine production is surpressed.")
AnnotationAssertion(terms:contributor obo:CL_0002061 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002061 "2010-06-22T11:18:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002061 "T helper cells type 9")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002061 "T(H)-9 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18931678") oboInOwl:hasExactSynonym obo:CL_0002061 "Th9")
AnnotationAssertion(rdfs:label obo:CL_0002061 "T-helper 9 cell")
EquivalentClasses(obo:CL_0002061 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000008982) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002215) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032638)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002061 obo:CL_0000492)

# Class: obo:CL_0002062 (pulmonary alveolar type 1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20054144") Annotation(oboInOwl:hasDbXref "PMID:29463737") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0002062 "A squamous pulmonary alveolar epithelial cell that is flattened and branched. A pulmonary alveolar type 1 cell covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange.")
AnnotationAssertion(terms:contributor obo:CL_0002062 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002062 "2010-06-23T04:37:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002062 "BTO:0000780")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002062 "FMA:62500")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "lung type 1 cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "membranous pneumocytes")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "pulmonary alveolar type I cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "small alveolar cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "squamous alveolar cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "squamous alveolar lining cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "type 1 alveolar epithelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32491474") oboInOwl:hasExactSynonym obo:CL_0002062 "type 1 pneumocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "type I alveolar cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "type I alveolar epithelial cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002062 "type I pneumocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29463737") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002062 "AT1")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002062 "ATI")
AnnotationAssertion(rdfs:label obo:CL_0002062 "pulmonary alveolar type 1 cell")
EquivalentClasses(obo:CL_0002062 ObjectIntersectionOf(obo:CL_0000322 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007585)))
SubClassOf(obo:CL_0002062 obo:CL_0000076)

# Class: obo:CL_0002063 (pulmonary alveolar type 2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "PMID:36138472") Annotation(oboInOwl:hasDbXref "PMID:8540632") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de") obo:IAO_0000115 obo:CL_0002063 "A pulmonary alveolar epithelial cell that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants via specialized organelles called alveolar lamellar bodies. This cell type also contributes to tissue repair and can differentiate after injury into a pulmonary alveolar type 1 cell. This cuboidal cell is thicker than squamous alveolar cells, has a rounded apical surface that projects above the level of the surrounding epithelium, and its free surface is covered by short microvilli.")
AnnotationAssertion(terms:contributor obo:CL_0002063 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002063 "2010-06-24T12:04:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002063 "BTO:0000538")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002063 "FMA:62501")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "cuboidal type II cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "granular pneumocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "great alveolar cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "lung type 2 cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type 2 alveolar epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type 2 alveolocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type 2 pneumocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type II alveolar cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type II alveolar epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002063 "type II alveolocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32491474") oboInOwl:hasExactSynonym obo:CL_0002063 "type II pneumocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36138472") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002063 "AT2")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002063 "ATII")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002063 "TII")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002063 "lung type II cell")
AnnotationAssertion(rdfs:label obo:CL_0002063 "pulmonary alveolar type 2 cell")
EquivalentClasses(obo:CL_0002063 ObjectIntersectionOf(obo:CL_0000322 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043129)))
SubClassOf(obo:CL_0002063 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0097208))
SubClassOf(obo:CL_0002063 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001872))
SubClassOf(obo:CL_0002063 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4040003))

# Class: obo:CL_0002064 (pancreatic acinar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:20395539") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells") obo:IAO_0000115 obo:CL_0002064 "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules.")
AnnotationAssertion(terms:contributor obo:CL_0002064 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002064 "2010-06-24T03:16:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002064 "BTO:0000028")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002064 "CALOHA:TS-0737")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002064 "FMA:63032")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002064 "acinar cell of pancreas")
AnnotationAssertion(rdfs:label obo:CL_0002064 "pancreatic acinar cell")
EquivalentClasses(obo:CL_0002064 ObjectIntersectionOf(obo:CL_0000622 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001263)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002064 obo:CL_0000083)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002064 obo:CL_0000622)
SubClassOf(obo:CL_0002064 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042589))

# Class: obo:CL_0002065 (obo:CL_0002065)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002065 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002065 obo:CL_0000577)
AnnotationAssertion(owl:deprecated obo:CL_0002065 "true"^^xsd:boolean)

# Class: obo:CL_0002066 (Feyrter cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002066 "A neuroendocrine cell found in the epithelium of the lungs and respiratory tract. This cell type is rounded or elliptical in shape, situated mainly in the basal part of the epithelium; regulates bronchial secretion, smooth muscle contraction, lobular growth, ciliary activity and chemoreception. Cell has an electron-lucent cytoplasm, contains numerous dense-cored vesicles with a clear halo between the core and the limiting membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002066 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002066 "2010-06-28T08:24:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002066 "FMA:14118")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002066 "Kultschitzky cell of bronchiole")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002066 "bronchiolar Kulchitsky cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002066 "respiratory enterochromaffin cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002066 "P cell")
AnnotationAssertion(rdfs:label obo:CL_0002066 "Feyrter cell")
SubClassOf(obo:CL_0002066 obo:CL_0000165)

# Class: obo:CL_0002067 (type A enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") obo:IAO_0000115 obo:CL_0002067 "An enteroendocrine cell that produces glucagon.")
AnnotationAssertion(terms:contributor obo:CL_0002067 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002067 "2010-09-10T10:48:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002067 "FMA:62939")
AnnotationAssertion(rdfs:label obo:CL_0002067 "type A enteroendocrine cell")
EquivalentClasses(obo:CL_0002067 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070091)))

# Class: obo:CL_0002068 (Purkinje myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0412046911") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19939742") obo:IAO_0000115 obo:CL_0002068 "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter.")
AnnotationAssertion(terms:contributor obo:CL_0002068 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002068 "2010-06-28T08:36:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002068 "BTO:0001032")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002068 "FMA:14146")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002068 "Purkinje cell fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002068 "Purkinje muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002068 "myocytus conducens cardiacus")
AnnotationAssertion(rdfs:label obo:CL_0002068 "Purkinje myocyte")
SubClassOf(obo:CL_0002068 obo:CL_0002086)

# Class: obo:CL_0002069 (type II vestibular sensory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002069 "Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices.")
AnnotationAssertion(terms:contributor obo:CL_0002069 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002069 "2010-06-29T09:58:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002069 "FMA:67909")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002069 "type 2 vestibular hair cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002069 "type 2 vestibular sensory cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002069 "type II hair cell")
AnnotationAssertion(rdfs:label obo:CL_0002069 "type II vestibular sensory cell")
SubClassOf(obo:CL_0002069 obo:CL_0000609)

# Class: obo:CL_0002070 (type I vestibular sensory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002070 "Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending.")
AnnotationAssertion(terms:contributor obo:CL_0002070 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002070 "2010-06-29T09:58:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002070 "FMA:62352")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002070 "type 1 vestibular hair cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002070 "type 1 vestibular sensory cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002070 "type I hair cell")
AnnotationAssertion(rdfs:label obo:CL_0002070 "type I vestibular sensory cell")
SubClassOf(obo:CL_0002070 obo:CL_0000609)

# Class: obo:CL_0002071 (enterocyte of epithelium of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:22288583") Annotation(oboInOwl:hasDbXref "PMID:35626748") Annotation(oboInOwl:hasDbXref "PMID:38872928") obo:IAO_0000115 obo:CL_0002071 "A columnar absorptive epithelial cell found in the epithelium of large intestine, specialized for water and electrolyte absorption. Unlike small intestinal enterocytes, those in the large intestine have fewer apical microvilli.")
AnnotationAssertion(terms:contributor obo:CL_0002071 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002071 "2010-06-29T11:07:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002071 "columnar cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002071 "BTO:0002484")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002071 "FMA:63638")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002071 "FMA:66771")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002071 "columnar cell of the colon")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002071 "vacuolar absorptive cell")
AnnotationAssertion(rdfs:label obo:CL_0002071 "enterocyte of epithelium of large intestine")
EquivalentClasses(obo:CL_0002071 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002071 obo:CL_0002253)

# Class: obo:CL_0002072 (nodal myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67101") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002072 "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.")
AnnotationAssertion(terms:contributor obo:CL_0002072 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002072 "2010-06-29T11:41:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002072 "pacemaker cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002072 "BTO:0004190")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002072 "FMA:67101")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002072 "P cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_0002072 "cardiac pacemaker cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002072 "myocytus nodalis")
AnnotationAssertion(rdfs:label obo:CL_0002072 "nodal myocyte")
SubClassOf(obo:CL_0002072 obo:CL_0002086)

# Class: obo:CL_0002073 (transitional myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67142") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002073 "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002073 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002073 "2010-06-29T02:39:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002073 "FMA:67142")
AnnotationAssertion(rdfs:label obo:CL_0002073 "transitional myocyte")
SubClassOf(obo:CL_0002073 obo:CL_0002086)

# Class: obo:CL_0002074 (myocardial endocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67111") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002074 "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides).")
AnnotationAssertion(terms:contributor obo:CL_0002074 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002074 "2010-06-29T11:50:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002074 "FMA:67111")
AnnotationAssertion(rdfs:label obo:CL_0002074 "myocardial endocrine cell")
SubClassOf(obo:CL_0002074 obo:CL_0000163)
SubClassOf(obo:CL_0002074 obo:CL_0002086)

# Class: obo:CL_0002075 (brush cell of tracheobronchial tree)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15817800") Annotation(oboInOwl:hasDbXref "PMID:30291131") Annotation(oboInOwl:hasDbXref "PMID:37925434") obo:IAO_0000115 obo:CL_0002075 "A rare type of columnar epithelial cell that is part of the tracheobronchial epithelium. This cell is characterized by a distinctive tuft of apical microvilli, which extends into the cytoplasm, and a pear-shaped morphology, broad at the base and tapering to a narrow apex. It plays vital roles in chemosensation, producing cytokines like IL-25, and enhancing mucociliary clearance through acetylcholine release to support mucus movement and airway defense.")
AnnotationAssertion(terms:contributor obo:CL_0002075 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002075 "2010-06-29T03:22:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002075 "pulmonary brush cell")
AnnotationAssertion(rdfs:label obo:CL_0002075 "brush cell of tracheobronchial tree")
EquivalentClasses(obo:CL_0002075 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008397)))
SubClassOf(obo:CL_0002075 obo:CL_0000075)

# Class: obo:CL_0002076 (endo-epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69075") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002076 "An epithelial cell derived from endoderm.")
AnnotationAssertion(terms:contributor obo:CL_0002076 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002076 "2010-06-29T03:38:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002076 "FMA:69075")
AnnotationAssertion(rdfs:label obo:CL_0002076 "endo-epithelial cell")
EquivalentClasses(obo:CL_0002076 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000223)))

# Class: obo:CL_0002077 (ecto-epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69074") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002077 "An epithelial cell derived from ectoderm.")
AnnotationAssertion(terms:contributor obo:CL_0002077 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002077 "2010-06-29T03:38:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002077 "FMA:69074")
AnnotationAssertion(rdfs:label obo:CL_0002077 "ecto-epithelial cell")
EquivalentClasses(obo:CL_0002077 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000221)))

# Class: obo:CL_0002078 (meso-epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69076") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002078 "Epithelial cell derived from mesoderm or mesenchyme.")
AnnotationAssertion(terms:contributor obo:CL_0002078 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002078 "2010-06-29T03:49:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002078 "FMA:69076")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002078 "epithelial mesenchymal cell")
AnnotationAssertion(rdfs:label obo:CL_0002078 "meso-epithelial cell")
EquivalentClasses(obo:CL_0002078 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222)))

# Class: obo:CL_0002079 (pancreatic ductal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:63099") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:14740223") obo:IAO_0000115 obo:CL_0002079 "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH.")
AnnotationAssertion(terms:contributor obo:CL_0002079 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002079 "2010-06-30T08:49:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002079 "FMA:63099")
AnnotationAssertion(rdfs:label obo:CL_0002079 "pancreatic ductal cell")
EquivalentClasses(obo:CL_0002079 ObjectIntersectionOf(obo:CL_0000083 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001064) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015106)))
SubClassOf(obo:CL_0002079 obo:CL_0000069)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002079 obo:CL_0000083)

# Class: obo:CL_0002080 (pancreatic centro-acinar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12142741") Annotation(oboInOwl:hasDbXref "PMID:20018761") Annotation(oboInOwl:hasDbXref "PMID:8185160") obo:IAO_0000115 obo:CL_0002080 "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types.")
AnnotationAssertion(terms:contributor obo:CL_0002080 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002080 "2010-06-30T08:49:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002080 "FMA:62455")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002080 "centroacinar cell of Langerhans")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002080 "pancreatic centroacinar cell")
AnnotationAssertion(rdfs:label obo:CL_0002080 "pancreatic centro-acinar cell")
EquivalentClasses(obo:CL_0002080 ObjectIntersectionOf(obo:CL_0000083 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001263) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015106)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002080 obo:CL_0000083)

# Class: obo:CL_0002081 (type II cell of carotid body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7938227") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Carotid_body") obo:IAO_0000115 obo:CL_0002081 "This cell resembles a glia cell, express the glial marker S100 and act as a supporting cell to type I cell. This cell is located in a small cluster of type I and type II cells near the fork of the carotid artery.")
AnnotationAssertion(terms:contributor obo:CL_0002081 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002081 "2010-06-30T04:23:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002081 "FMA:84187")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002081 "sheath cell of carotid body")
AnnotationAssertion(rdfs:label obo:CL_0002081 "type II cell of carotid body")
SubClassOf(obo:CL_0002081 obo:CL_0000703)
SubClassOf(obo:CL_0002081 obo:CL_0002256)

# Class: obo:CL_0002082 (type II cell of adrenal medulla)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002082 "A chromaffin cell of the adrenal medulla that produces epinephrine.")
AnnotationAssertion(terms:contributor obo:CL_0002082 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002082 "2010-07-14T09:41:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002082 "FMA:69322")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002082 "adrenal secreting cell of the adrenal medulla")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002082 "adrenergic chromaffin cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002082 "epiniphrine secreting cell of the adrenal medulla")
AnnotationAssertion(rdfs:label obo:CL_0002082 "type II cell of adrenal medulla")
EquivalentClasses(obo:CL_0002082 ObjectIntersectionOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048242)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002082 obo:CL_0000336)

# Class: obo:CL_0002083 (type I cell of adrenal medulla)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002083 "A chromaffin cell of the adrenal medulla that produces norepinephrine.")
AnnotationAssertion(terms:contributor obo:CL_0002083 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002083 "2010-07-14T10:12:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002083 "FMA:69321")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002083 "noradrenergic chromaffin cell")
AnnotationAssertion(rdfs:label obo:CL_0002083 "type I cell of adrenal medulla")
EquivalentClasses(obo:CL_0002083 ObjectIntersectionOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048243)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002083 obo:CL_0000336)

# Class: obo:CL_0002084 (Boettcher cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Boettcher_cell") obo:IAO_0000115 obo:CL_0002084 "A Boettcher cell is a polyhedral cells on the basilar membrane of the cochlea, and is located beneath Claudius cells. A Boettcher cell is considered a supporting cell for the organ of Corti, and is present only in the lower turn of the cochlea. These cells interweave with each other, and project microvilli into the intercellular space. Because of their structural specialization, a Boettcher cell is believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca(2+) regulation and ion transport.")
AnnotationAssertion(terms:contributor obo:CL_0002084 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002084 "2010-07-14T03:22:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002084 "Boettcher's cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002084 "Bottcher cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002084 "Bottcher's cell")
AnnotationAssertion(rdfs:label obo:CL_0002084 "Boettcher cell")
SubClassOf(obo:CL_0002084 obo:CL_0002315)

# Class: obo:CL_0002085 (tanycyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:29351662") Annotation(oboInOwl:hasDbXref "http://neurolex.org/wiki/Category:Tanycyte") obo:IAO_0000115 obo:CL_0002085 "A specialized elongated ventricular ependymal cell with one or more processes that extend into the brain parenchyma or associated blood vessels where they contact blood vessel endothelial cells and/or neurons. These cells are found in the ventricles and circumventricular organs of the brain. They are involved in hormonal regulation, gatekeeping molecules between the bloodstream and cerebrospinal fluid, metabolic sensing, and regulating food intake.")
AnnotationAssertion(terms:contributor obo:CL_0002085 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002085 "2010-07-15T11:21:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002085 "BTO:0001953")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002085 "FMA:54560")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasExactSynonym obo:CL_0002085 "stretch cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") oboInOwl:hasNarrowSynonym obo:CL_0002085 "tanycyte-like cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") rdfs:comment obo:CL_0002085 "This class includes cells that are sometimes referred to as tanycyte-like cells,  located in circumventricular organs (Langlet et al., 2023) as well as tanycytes located in the ventricles.")
AnnotationAssertion(rdfs:label obo:CL_0002085 "tanycyte")
SubClassOf(obo:CL_0002085 obo:CL_0000065)
SubClassOf(obo:CL_0002085 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004670))

# Class: obo:CL_0002086 (specialized cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67968") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002086 "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart.")
AnnotationAssertion(terms:contributor obo:CL_0002086 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002086 "2010-07-21T01:33:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002086 "FMA:67968")
AnnotationAssertion(rdfs:label obo:CL_0002086 "specialized cardiac myocyte")
SubClassOf(obo:CL_0002086 obo:CL_0000746)

# Class: obo:CL_0002087 (nongranular leukocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002087 "A leukocyte that lacks granules.")
AnnotationAssertion(terms:contributor obo:CL_0002087 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002087 "2010-07-22T11:30:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002087 "FMA:62855")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002087 "agranular leukocyte")
AnnotationAssertion(rdfs:label obo:CL_0002087 "nongranular leukocyte")
EquivalentClasses(obo:CL_0002087 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0030141)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002087 obo:CL_0000738)

# Class: obo:CL_0002088 (interstitial cell of Cajal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16460275") Annotation(oboInOwl:hasDbXref "PMID:19520112") obo:IAO_0000115 obo:CL_0002088 "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.")
AnnotationAssertion(terms:contributor obo:CL_0002088 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002088 "2010-07-22T03:26:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002088 "BTO:0003914")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002088 "FMA:86573")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002088 "ICC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_0002088 "intestinal pacemaker cell")
AnnotationAssertion(rdfs:comment obo:CL_0002088 "Some argue this cell type is of mesenchymal origin.")
AnnotationAssertion(rdfs:label obo:CL_0002088 "interstitial cell of Cajal")
EquivalentClasses(obo:CL_0002088 ObjectIntersectionOf(obo:CL_0000710 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043134)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002088 obo:CL_0000710)

# Class: obo:CL_0002089 (group 2 innate lymphoid cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20200518") obo:IAO_0000115 obo:CL_0002089 "A group 2 innate lymphoid cell in the mouse capable of secreting IL-13 in response to a helminth infection. This cell is lineage-negative, ICOS-positive, IL1RL1-positive, IL7Ralpha-positive, and IL17Br-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002089 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002089 "2010-08-12T02:22:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002089 "nuocyte")
AnnotationAssertion(rdfs:label obo:CL_0002089 "group 2 innate lymphoid cell, mouse")
EquivalentClasses(obo:CL_0002089 ObjectIntersectionOf(obo:CL_0001069 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001008) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001326) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001893) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001927) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000007431) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001860) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000008982) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000008994) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032616)))

# Class: obo:CL_0002090 (polar body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Polar_body") obo:IAO_0000115 obo:CL_0002090 "One of two small cells formed by the first and second meiotic division of oocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002090 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002090 "2010-08-23T09:49:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002090 "EHDAA2:0004716")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002090 "FMA:85543")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002090 "MESH:D059705")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002090 "WBbt:0008429")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002090 "XAO:0000262")
AnnotationAssertion(rdfs:label obo:CL_0002090 "polar body")
SubClassOf(obo:CL_0002090 obo:CL_0000021)

# Class: obo:CL_0002091 (primary polar body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002091 "A small cell formed by the first meiotic division of oocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002091 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002091 "2010-08-23T09:49:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002091 "EHDAA2:0000541")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002091 "EMAPA:16032")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002091 "FMA:18650")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002091 "VHOG:0000464")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "EHDAA2:0000541") oboInOwl:hasExactSynonym obo:CL_0002091 "first polar body")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:18650") oboInOwl:hasExactSynonym obo:CL_0002091 "polocytus primarius")
AnnotationAssertion(rdfs:label obo:CL_0002091 "primary polar body")
SubClassOf(obo:CL_0002091 obo:CL_0002090)

# Class: obo:CL_0002092 (bone marrow cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002092 "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.")
AnnotationAssertion(terms:contributor obo:CL_0002092 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002092 "2010-07-22T04:48:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002092 "BTO:0004850")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002092 "FMA:83621")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002092 "MESH:D001854")
AnnotationAssertion(rdfs:comment obo:CL_0002092 "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.")
AnnotationAssertion(rdfs:label obo:CL_0002092 "bone marrow cell")
EquivalentClasses(obo:CL_0002092 ObjectIntersectionOf(obo:CL_0001035 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002092 obo:CL_0001035)

# Class: obo:CL_0002093 (secondary polar body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002093 "A small cell formed by the second meiotic division of oocytes. In mammals, the second polar body may fail to form unless the ovum has been penetrated by a sperm cell.")
AnnotationAssertion(terms:contributor obo:CL_0002093 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002093 "2010-08-23T09:50:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002093 "EHDAA2:0001820")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002093 "EMAPA:16034")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002093 "EMAPA:16045")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002093 "FMA:18651")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:18651") oboInOwl:hasExactSynonym obo:CL_0002093 "polocytus secundarius")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "EHDAA2:0001820") oboInOwl:hasExactSynonym obo:CL_0002093 "second polar body")
AnnotationAssertion(rdfs:label obo:CL_0002093 "secondary polar body")
SubClassOf(obo:CL_0002093 obo:CL_0002090)

# Class: obo:CL_0002094 (interstitial cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002094 "A cell that makes up the loose connective tissue of the ovary.")
AnnotationAssertion(terms:contributor obo:CL_0002094 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002094 "2010-08-23T11:11:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002094 "FMA:18709")
AnnotationAssertion(rdfs:label obo:CL_0002094 "interstitial cell of ovary")
SubClassOf(obo:CL_0002094 obo:CL_0002132)

# Class: obo:CL_0002095 (hilus cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002095 "A cell in the hilum of the ovary that produces androgens.")
AnnotationAssertion(terms:contributor obo:CL_0002095 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002095 "2010-08-23T11:18:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002095 "FMA:18710")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002095 "hilar cell of ovary")
AnnotationAssertion(rdfs:label obo:CL_0002095 "hilus cell of ovary")
SubClassOf(obo:CL_0002095 obo:CL_0000593)
SubClassOf(obo:CL_0002095 obo:CL_0002132)

# Class: obo:CL_0002096 (internodal tract myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781729300") obo:IAO_0000115 obo:CL_0002096 "A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals.")
AnnotationAssertion(terms:contributor obo:CL_0002096 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002096 "2010-08-23T11:24:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002096 "FMA:223275")
AnnotationAssertion(rdfs:label obo:CL_0002096 "internodal tract myocyte")
EquivalentClasses(obo:CL_0002096 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009966)))
SubClassOf(obo:CL_0002096 obo:CL_0002086)

# Class: obo:CL_0002097 (cortical cell of adrenal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002097 "A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol.")
AnnotationAssertion(terms:contributor obo:CL_0002097 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002097 "2010-08-24T01:37:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002097 "FMA:69545")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002097 "adrenal cortex cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002097 "adrenocortical cell")
AnnotationAssertion(rdfs:label obo:CL_0002097 "cortical cell of adrenal gland")
EquivalentClasses(obo:CL_0002097 ObjectIntersectionOf(obo:CL_0002078 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001235)))
SubClassOf(obo:CL_0002097 obo:CL_0000150)
SubClassOf(obo:CL_0002097 obo:CL_0000174)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002097 obo:CL_0002078)

# Class: obo:CL_0002098 (regular cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002098 "A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval.")
AnnotationAssertion(terms:contributor obo:CL_0002098 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002098 "2010-08-23T11:33:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002098 "FMA:67967")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002098 "regular cardiac muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002098 "regular cardiac muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002098 "regular cardiac myocyte")
SubClassOf(obo:CL_0002098 obo:CL_0000746)

# Class: obo:CL_0002099 (type I cell of adrenal cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002099 "A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids.")
AnnotationAssertion(terms:contributor obo:CL_0002099 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002099 "2010-08-24T01:42:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002099 "FMA:69273")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002099 "epithelial cell of zona glomerulosa of adrenal gland")
AnnotationAssertion(rdfs:label obo:CL_0002099 "type I cell of adrenal cortex")
EquivalentClasses(obo:CL_0002099 ObjectIntersectionOf(obo:CL_0002097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002053)))
SubClassOf(obo:CL_0002099 obo:CL_0000456)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002099 obo:CL_0002097)

# Class: obo:CL_0002100 (regular interventricular cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002100 "A regular cardiac myocyte of the interventricular region of the heart.")
AnnotationAssertion(terms:contributor obo:CL_0002100 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002100 "2010-08-23T11:40:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002100 "FMA:228792")
AnnotationAssertion(rdfs:label obo:CL_0002100 "regular interventricular cardiac myocyte")
SubClassOf(obo:CL_0002100 obo:CL_0002098)

# Class: obo:CL_0002101 (CD38-positive naive B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002101 "A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38+ naive B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38+ naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38+ naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38+ naive B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38-positive naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38-positive naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38-positive naive B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002101 "CD38-positive naive B cell")
EquivalentClasses(obo:CL_0002101 ObjectIntersectionOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002101 obo:CL_0000788)

# Class: obo:CL_0002102 (CD38-negative naive B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002102 "A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38- naive B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38- naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38- naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38- naive B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38-negative naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38-negative naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38-negative naive B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002102 "CD38-negative naive B cell")
EquivalentClasses(obo:CL_0002102 ObjectIntersectionOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002102 obo:CL_0000788)

# Class: obo:CL_0002103 (IgG-positive double negative memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002103 "An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ dn memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ dn memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ dn memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ dn memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ double negative memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ double negative memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ double negative memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG+ double negative memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive dn memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive dn memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive dn memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive dn memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive double negative memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive double negative memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive double negative memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002103 "IgG-positive double negative memory B cell")
EquivalentClasses(obo:CL_0002103 ObjectIntersectionOf(obo:CL_0000981 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071735)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002103 obo:CL_0000981)

# Class: obo:CL_0002104 (IgG-negative double negative memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002104 "An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- dn memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- dn memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- dn memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- dn memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- double negative memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- double negative memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- double negative memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG- double negative memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative dn memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative dn memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative dn memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative dn memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative double negative memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative double negative memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative double negative memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002104 "IgG-negative double negative memory B cell")
EquivalentClasses(obo:CL_0002104 ObjectIntersectionOf(obo:CL_0000981 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002104 obo:CL_0000981)

# Class: obo:CL_0002105 (CD38-positive IgG memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002105 "A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38+ IgG memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38+ IgG memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38+ IgG memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38+ IgG memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38-positive IgG memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38-positive IgG memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38-positive IgG memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002105 "CD38-positive IgG memory B cell")
EquivalentClasses(obo:CL_0002105 ObjectIntersectionOf(obo:CL_0000979 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002105 obo:CL_0000979)

# Class: obo:CL_0002106 (IgD-positive CD38-positive IgG memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002106 "An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002106 "IgD-positive CD38-positive IgG memory B cell")
EquivalentClasses(obo:CL_0002106 ObjectIntersectionOf(obo:CL_0002105 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002106 obo:CL_0002105)

# Class: obo:CL_0002107 (IgD-negative CD38-positive IgG memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002107 "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002107 "IgD-negative CD38-positive IgG memory B cell")
EquivalentClasses(obo:CL_0002107 ObjectIntersectionOf(obo:CL_0002105 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002107 obo:CL_0002105)

# Class: obo:CL_0002108 (CD38-negative IgG memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002108 "A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002108 "CD38-negative IgG memory B cell")
EquivalentClasses(obo:CL_0002108 ObjectIntersectionOf(obo:CL_0000979 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002108 obo:CL_0000979)

# Class: obo:CL_0002109 (B220-positive CD38-positive naive B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002109 "A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220+CD38+ naive B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220+CD38+ naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220+CD38+ naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220+CD38+ naive B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220-positive CD38-positive naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220-positive CD38-positive naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "B220-positive CD38-positive naive B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002109 "B220-positive CD38-positive naive B cell")
EquivalentClasses(obo:CL_0002109 ObjectIntersectionOf(obo:CL_0002101 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002109 obo:CL_0002101)

# Class: obo:CL_0002110 (B220-low CD38-positive naive B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002110 "A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.")
AnnotationAssertion(rdfs:label obo:CL_0002110 "B220-low CD38-positive naive B cell")
EquivalentClasses(obo:CL_0002110 ObjectIntersectionOf(obo:CL_0002101 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002110 obo:CL_0002101)

# Class: obo:CL_0002111 (CD38-negative unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002111 "An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38- unswitched memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38- unswitched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38- unswitched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38- unswitched memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38-negative unswitched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38-negative unswitched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38-negative unswitched memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002111 "CD38-negative unswitched memory B cell")
EquivalentClasses(obo:CL_0002111 ObjectIntersectionOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002111 obo:CL_0000970)

# Class: obo:CL_0002112 (B220-positive CD38-negative unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002112 "A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002112 "B220-positive CD38-negative unswitched memory B cell")
EquivalentClasses(obo:CL_0002112 ObjectIntersectionOf(obo:CL_0002111 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002112 obo:CL_0002111)

# Class: obo:CL_0002113 (B220-low CD38-negative unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002113 "A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002113 "B220-low CD38-negative unswitched memory B cell")
EquivalentClasses(obo:CL_0002113 ObjectIntersectionOf(obo:CL_0002111 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002113 obo:CL_0002111)

# Class: obo:CL_0002114 (CD38-positive unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002114 "A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38+ unswitched memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38+ unswitched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38+ unswitched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38+ unswitched memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38-positive unswitched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38-positive unswitched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38-positive unswitched memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002114 "CD38-positive unswitched memory B cell")
EquivalentClasses(obo:CL_0002114 ObjectIntersectionOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002114 obo:CL_0000970)

# Class: obo:CL_0002115 (B220-positive CD38-positive unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002115 "A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002115 "B220-positive CD38-positive unswitched memory B cell")
EquivalentClasses(obo:CL_0002115 ObjectIntersectionOf(obo:CL_0002114 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002115 obo:CL_0002114)

# Class: obo:CL_0002116 (B220-low CD38-positive unswitched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002116 "A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002116 "B220-low CD38-positive unswitched memory B cell")
EquivalentClasses(obo:CL_0002116 ObjectIntersectionOf(obo:CL_0002114 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002116 obo:CL_0002114)

# Class: obo:CL_0002117 (IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002117 "A class switched memory B cell that lacks IgG on the cell surface.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG- class switched memory B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG- class switched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG- class switched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG- class switched memory B-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG-negative class switched memory B lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG-negative class switched memory B-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG-negative class switched memory B-lymphocyte")
AnnotationAssertion(rdfs:label obo:CL_0002117 "IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002117 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002117 obo:CL_0000972)
SubClassOf(obo:CL_0002117 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738))

# Class: obo:CL_0002118 (CD38-negative IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002118 "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002118 "CD38-negative IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002118 ObjectIntersectionOf(obo:CL_0002117 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002118 obo:CL_0002117)

# Class: obo:CL_0002119 (CD38-positive IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002119 "A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002119 "CD38-positive IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002119 ObjectIntersectionOf(obo:CL_0002117 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002119 obo:CL_0002117)

# Class: obo:CL_0002120 (CD24-positive CD38-negative IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002120 "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002120 "CD24-positive CD38-negative IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002120 ObjectIntersectionOf(obo:CL_0002118 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002120 obo:CL_0002118)

# Class: obo:CL_0002121 (CD24-negative CD38-negative IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002121 "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002121 "CD24-negative CD38-negative IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002121 ObjectIntersectionOf(obo:CL_0002118 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002121 obo:CL_0002118)

# Class: obo:CL_0002122 (B220-positive CD38-positive IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002122 "A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002122 "B220-positive CD38-positive IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002122 ObjectIntersectionOf(obo:CL_0002119 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002122 obo:CL_0002119)

# Class: obo:CL_0002123 (B220-low CD38-positive IgG-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002123 "A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002123 "B220-low CD38-positive IgG-negative class switched memory B cell")
EquivalentClasses(obo:CL_0002123 ObjectIntersectionOf(obo:CL_0002119 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002123 obo:CL_0002119)

# Class: obo:CL_0002124 (CD27-positive gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19270712") obo:IAO_0000115 obo:CL_0002124 "A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma.")
AnnotationAssertion(terms:contributor obo:CL_0002124 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002124 "2010-08-18T09:57:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002124 "gammadelta27-positive")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002124 "gd27-positive")
AnnotationAssertion(rdfs:label obo:CL_0002124 "CD27-positive gamma-delta T cell")
EquivalentClasses(obo:CL_0002124 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002124 obo:CL_0000800)
SubClassOf(obo:CL_0002124 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002126))

# Class: obo:CL_0002125 (CD27-negative gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19270712") obo:IAO_0000115 obo:CL_0002125 "A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion.")
AnnotationAssertion(terms:contributor obo:CL_0002125 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002125 "2010-08-18T09:57:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21976777") oboInOwl:hasExactSynonym obo:CL_0002125 "gammadelta-17 cells")
AnnotationAssertion(rdfs:label obo:CL_0002125 "CD27-negative gamma-delta T cell")
EquivalentClasses(obo:CL_0002125 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003455) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032620) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002125 obo:CL_0000800)
SubClassOf(obo:CL_0002125 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002126))

# Class: obo:CL_0002126 (CD25-positive, CD27-positive immature gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19270712") obo:IAO_0000115 obo:CL_0002126 "A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low).")
AnnotationAssertion(terms:contributor obo:CL_0002126 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002126 "2010-08-18T10:35:37Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002126 "CD25-positive, CD27-positive immature gamma-delta T cell")
EquivalentClasses(obo:CL_0002126 ObjectIntersectionOf(obo:CL_0000799 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001919) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001083) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001839)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002126 obo:CL_0000799)

# Class: obo:CL_0002127 (innate effector T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20581831") obo:IAO_0000115 obo:CL_0002127 "A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation.")
AnnotationAssertion(terms:contributor obo:CL_0002127 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002127 "2010-08-20T02:14:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002127 "innate effector T cell")
EquivalentClasses(obo:CL_0002127 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002127 obo:CL_0000911)

# Class: obo:CL_0002128 (Tc17 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19201830") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0002128 "A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "CD8-positive Th17 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0002128 "Tc17 CD8+ T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Tc17 T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Tc17 T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Tc17 T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Tc17 T-lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Th17 CD8-positive T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002128 "Th17 non-TFH CD8-positive T cell")
AnnotationAssertion(rdfs:comment obo:CL_0002128 "This cell type is compatible with the HIPC Lyoplate markers for 'Tc17 CD8+ T cell', but its logical definition includes additional known characteristics of Tc17 T cells.  Found in the CD27-positive, CD28-positive or CD27-negative, CD28-positive fractions with the phenotype CCR4-negative and CCR7-negative (this sentence not part of definition).")
AnnotationAssertion(rdfs:label obo:CL_0002128 "Tc17 cell")
EquivalentClasses(obo:CL_0002128 ObjectIntersectionOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032620) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001201)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002128 obo:CL_0000908)

# Class: obo:CL_0002129 (regular atrial cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002129 "Regular cardiac myocyte of a cardiac atrium.")
AnnotationAssertion(terms:contributor obo:CL_0002129 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002129 "2010-08-23T11:41:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002129 "FMA:83108")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_0002129 "atrial cardiac muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002129 "atrial myocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002129 "regular atrial cardiac muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002129 "regular cardiac muscle cell of atrium")
AnnotationAssertion(rdfs:label obo:CL_0002129 "regular atrial cardiac myocyte")
SubClassOf(obo:CL_0002129 obo:CL_0002098)

# Class: obo:CL_0002130 (regular interatrial cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002130 "A cardiac myocyte of the interatrial region of the heart.")
AnnotationAssertion(terms:contributor obo:CL_0002130 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002130 "2010-08-23T11:41:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002130 "FMA:228790")
AnnotationAssertion(rdfs:label obo:CL_0002130 "regular interatrial cardiac myocyte")
SubClassOf(obo:CL_0002130 obo:CL_0002098)

# Class: obo:CL_0002131 (regular ventricular cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002131 "Regular cardiac myocyte of a cardiac ventricle.")
AnnotationAssertion(terms:contributor obo:CL_0002131 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002131 "2010-08-23T11:41:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasBroadSynonym obo:CL_0002131 "ventricular cardiac muscle cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002131 "FMA:83109")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002131 "regular cardiac muscle cell of ventricle")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002131 "regular ventricular cardiac muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002131 "ventricular myocyte")
AnnotationAssertion(rdfs:label obo:CL_0002131 "regular ventricular cardiac myocyte")
SubClassOf(obo:CL_0002131 obo:CL_0002098)

# Class: obo:CL_0002132 (stromal cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002132 "A stomal cell of the ovary")
AnnotationAssertion(terms:contributor obo:CL_0002132 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002132 "2010-08-23T12:10:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002132 "FMA:72299")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") oboInOwl:hasExactSynonym obo:CL_0002132 "ovarian stromal cell")
AnnotationAssertion(rdfs:label obo:CL_0002132 "stromal cell of ovary")
EquivalentClasses(obo:CL_0002132 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992)))

# Class: obo:CL_0002133 (stromal cell of ovarian cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002133 "A stromal cell of the ovarian cortex.")
AnnotationAssertion(terms:contributor obo:CL_0002133 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002133 "2010-08-23T12:12:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002133 "FMA:256169")
AnnotationAssertion(rdfs:label obo:CL_0002133 "stromal cell of ovarian cortex")
SubClassOf(obo:CL_0002133 obo:CL_0002132)

# Class: obo:CL_0002134 (stromal cell of ovarian medulla)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002134 "A stromal cell of the ovarian medulla.")
AnnotationAssertion(terms:contributor obo:CL_0002134 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002134 "2010-08-23T12:12:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002134 "FMA:256171")
AnnotationAssertion(rdfs:label obo:CL_0002134 "stromal cell of ovarian medulla")
EquivalentClasses(obo:CL_0002134 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013192)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002134 obo:CL_0002132)

# Class: obo:CL_0002135 (nonkeratinized cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") Annotation(oboInOwl:hasDbXref "PMID:1987287") obo:IAO_0000115 obo:CL_0002135 "Epidermal cells that do not contain keratin. Cell type is usually associated with moist epidermal tissues.")
AnnotationAssertion(terms:contributor obo:CL_0002135 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002135 "2010-08-24T08:43:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002135 "FMA:62880")
AnnotationAssertion(rdfs:label obo:CL_0002135 "nonkeratinized cell of epidermis")
SubClassOf(obo:CL_0002135 obo:CL_0000362)
SubClassOf(obo:CL_0002135 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))

# Class: obo:CL_0002136 (type II cell of adrenal cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002136 "A cell in the zona fasciculata that produce glucocorticoids, e.g cortisol.")
AnnotationAssertion(terms:contributor obo:CL_0002136 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002136 "2010-08-24T01:50:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002136 "FMA:69547")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002136 "type II cortical cell of adrenal gland")
AnnotationAssertion(rdfs:label obo:CL_0002136 "type II cell of adrenal cortex")
SubClassOf(obo:CL_0002136 obo:CL_0000460)
SubClassOf(obo:CL_0002136 obo:CL_0002097)

# Class: obo:CL_0002137 (type III cell of adrenal cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002137 "A cell in the zona reticularis that produce sex hormones.")
AnnotationAssertion(terms:contributor obo:CL_0002137 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002137 "2010-08-24T01:50:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002137 "FMA:69564")
AnnotationAssertion(rdfs:label obo:CL_0002137 "type III cell of adrenal cortex")
SubClassOf(obo:CL_0002137 obo:CL_0000593)
SubClassOf(obo:CL_0002137 obo:CL_0002097)

# Class: obo:CL_0002138 (endothelial cell of lymphatic vessel)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17846148") obo:IAO_0000115 obo:CL_0002138 "A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions.")
AnnotationAssertion(terms:contributor obo:CL_0002138 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002138 "2010-08-24T02:05:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002138 "BTO:0004167")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002138 "FMA:68458")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002138 "LEC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002138 "lymphatic endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002138 "endothelial cell of lymphatic vessel")
EquivalentClasses(obo:CL_0002138 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001473)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002138 obo:CL_0002139)
SubClassOf(obo:CL_0002138 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005022))

# Class: obo:CL_0002139 (endothelial cell of vascular tree)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12768659") obo:IAO_0000115 obo:CL_0002139 "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.")
AnnotationAssertion(terms:contributor obo:CL_0002139 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002139 "2010-08-24T02:06:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002139 "BTO:0001854")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002139 "CALOHA:TS-1106")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002139 "FMA:67755")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002139 "vascular endothelial cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0002139 "cubodial endothelial cell of vascular tree")
AnnotationAssertion(rdfs:comment obo:CL_0002139 "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002139 "endothelial cell of vascular tree")
SubClassOf(obo:CL_0002139 obo:CL_0000115)

# Class: obo:CL_0002140 (skin sebocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:37205445") obo:IAO_0000115 obo:CL_0002140 "An acinar cell that is part of a skin sebaceous gland. This cell produces and secretes sebum into hair follicles.")
AnnotationAssertion(terms:contributor obo:CL_0002140 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002140 "2010-08-24T09:27:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002140 "acinar cell of sebaceous gland")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002140 "BTO:0004613")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002140 "FMA:70953")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002140 "acinar cell of skin sebaceous gland")
AnnotationAssertion(rdfs:label obo:CL_0002140 "skin sebocyte")
EquivalentClasses(obo:CL_0002140 ObjectIntersectionOf(obo:CL_0000622 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003487)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002140 obo:CL_0000317)

# Class: obo:CL_0002141 (active chief cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0517223651") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002141 "A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1")
AnnotationAssertion(terms:contributor obo:CL_0002141 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002141 "2010-08-24T09:30:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002141 "FMA:69082")
AnnotationAssertion(rdfs:label obo:CL_0002141 "active chief cell of parathyroid gland")
SubClassOf(obo:CL_0002141 obo:CL_0000446)

# Class: obo:CL_0002142 (dark cell of eccrine sweat gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002142 "A cell pyramidal in shape, with their broad ends facing and forming the greater extent of the lining of the main lumen. Secretes glycoproteins associated with mucus.")
AnnotationAssertion(terms:contributor obo:CL_0002142 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002142 "2010-08-24T02:15:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002142 "FMA:70659")
AnnotationAssertion(rdfs:label obo:CL_0002142 "dark cell of eccrine sweat gland")
SubClassOf(obo:CL_0002142 obo:CL_0000318)
SubClassOf(obo:CL_0002142 obo:CL_0000434)
SubClassOf(obo:CL_0002142 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000423))

# Class: obo:CL_0002143 (dark chief cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002143 "A chief cell that is smaller than light chief cells and has a smaller and darker nucleus and a finely granular cytoplasm with many granules.")
AnnotationAssertion(terms:contributor obo:CL_0002143 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002143 "2010-08-24T02:18:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002143 "FMA:69080")
AnnotationAssertion(rdfs:label obo:CL_0002143 "dark chief cell of parathyroid gland")
SubClassOf(obo:CL_0002143 obo:CL_0000446)

# Class: obo:CL_0002144 (capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002144 "An endothelial cell found in capillaries.")
AnnotationAssertion(terms:contributor obo:CL_0002144 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002144 "2010-08-24T10:15:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002144 "BTO:0004956")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002144 "CALOHA:TS-0112")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002144 "FMA:67756")
AnnotationAssertion(rdfs:label obo:CL_0002144 "capillary endothelial cell")
EquivalentClasses(obo:CL_0002144 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001915)))
SubClassOf(obo:CL_0002144 obo:CL_0002653)

# Class: obo:CL_0002145 (multiciliated columnar cell of tracheobronchial tree)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:28400610") obo:IAO_0000115 obo:CL_0002145 "A multi-ciliated epithelial cell located in the trachea and bronchi, characterized by a columnar shape and motile cilia on its apical surface. These cilia facilitate mucociliary clearance by moving mucus and trapped particles toward the pharynx.")
AnnotationAssertion(terms:contributor obo:CL_0002145 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002145 "2010-08-24T03:38:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002145 "FMA:70542")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002145 "ciliated columnar cell of tracheobronchial tree")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1016/B978-032304048-8.50071-2>) Annotation(oboInOwl:hasDbXref "PMID:25386990") rdfs:comment obo:CL_0002145 "These cells possess numerous cilia on their surface, typically ranging from 200 to 300 per cell. The cilia vary in length, measuring between 6 to 7 μm in the upper airways (trachea) and becoming shorter, around 4 μm, in the smaller airways (terminal bronchioles). These cells form a two-layered 'coat' in the airway: the lower 'sol' layer is watery, allowing the cilia to beat in coordinated waves, while the upper 'gel' layer is thick and sticky, trapping inhaled particles.")
AnnotationAssertion(rdfs:label obo:CL_0002145 "multiciliated columnar cell of tracheobronchial tree")
EquivalentClasses(obo:CL_0002145 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008397) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))
SubClassOf(obo:CL_0002145 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002209))

# Class: obo:CL_0002146 (clear cell of eccrine sweat gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002146 "A sweat producing cell of eccrine sweat glands. Pyramidal in shape, with its base resting on the basal lamina or myoepitheliocytes, and its microvillus-covered apical plasma membrane line up the intercellular canaliculi. Cell is not stained by hematoxylin or eosin.")
AnnotationAssertion(terms:contributor obo:CL_0002146 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002146 "2010-08-24T10:33:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002146 "FMA:70658")
AnnotationAssertion(rdfs:label obo:CL_0002146 "clear cell of eccrine sweat gland")
SubClassOf(obo:CL_0002146 obo:CL_0000318)
SubClassOf(obo:CL_0002146 obo:CL_0000434)
SubClassOf(obo:CL_0002146 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000423))

# Class: obo:CL_0002147 (clear chief cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002147 "A chief cell of parathyroid glands that does not stain with hematoxylin or eosin. This cell is larger, has a larger nucleus and fewer secretory granules than dark chief cells.")
AnnotationAssertion(terms:contributor obo:CL_0002147 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002147 "2010-08-24T10:39:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002147 "FMA:69081")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002147 "clear chief cell of parathyroid cell")
AnnotationAssertion(rdfs:label obo:CL_0002147 "clear chief cell of parathyroid gland")
SubClassOf(obo:CL_0002147 obo:CL_0000446)

# Class: obo:CL_0002148 (dental pulp cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:36267574") obo:IAO_0000115 obo:CL_0002148 "A cell found within the dental pulp.")
AnnotationAssertion(terms:contributor obo:CL_0002148 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002148 "2010-08-24T02:52:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002148 "CALOHA:TS-0195")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002148 "FMA:87170")
AnnotationAssertion(rdfs:label obo:CL_0002148 "dental pulp cell")
EquivalentClasses(obo:CL_0002148 ObjectIntersectionOf(obo:CL_0002159 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001754)))

# Class: obo:CL_0002149 (epithelial cell of uterus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11331626") Annotation(oboInOwl:hasDbXref "PMID:16960017") Annotation(oboInOwl:hasDbXref "PMID:21698266") obo:IAO_0000115 obo:CL_0002149 "An epithelial cell of the uterus. This cell has a mesodermal origin.")
AnnotationAssertion(terms:contributor obo:CL_0002149 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002149 "2010-08-24T10:45:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002149 "FMA:256161")
AnnotationAssertion(rdfs:label obo:CL_0002149 "epithelial cell of uterus")
EquivalentClasses(obo:CL_0002149 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006955)))
SubClassOf(obo:CL_0002149 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))

# Class: obo:CL_0002150 (epithelioid macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D015622") Annotation(oboInOwl:hasDbXref "PMID:12673090") obo:IAO_0000115 obo:CL_0002150 "Epithelioid macrophage is an activated macrophage that resembles an epithelial cell with finely granular, pale eosinophilic cytoplasm and central, ovoid nucleus (oval or elongate). This cell type is able to merge into one another to form aggregates. The presence of such aggregates may characterize some pathologic conditions, mainly granulomatous inflammation.")
AnnotationAssertion(terms:contributor obo:CL_0002150 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002150 "2010-08-24T03:48:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002150 "epithelioid cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002150 "FMA:83514")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D015622") Annotation(oboInOwl:hasDbXref "PMID:12673090") oboInOwl:hasExactSynonym obo:CL_0002150 "epithelioid histocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002150 "epitheloid macrophage")
AnnotationAssertion(rdfs:label obo:CL_0002150 "epithelioid macrophage")
SubClassOf(obo:CL_0002150 obo:CL_0000235)
SubClassOf(obo:CL_0002150 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000861))

# Class: obo:CL_0002151 (late promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0412046911") obo:IAO_0000115 obo:CL_0002151 "A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous.")
AnnotationAssertion(terms:contributor obo:CL_0002151 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002151 "2010-08-24T03:07:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002151 "FMA:83534")
AnnotationAssertion(rdfs:label obo:CL_0002151 "late promyelocyte")
SubClassOf(obo:CL_0002151 obo:CL_0000836)

# Class: obo:CL_0002152 (columnar cell of endocervix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "doi:/10.1016/j.autneu.2015.04.008") obo:IAO_0000115 obo:CL_0002152 "A simple columnar epithelial cell located in the endocervix.")
AnnotationAssertion(terms:contributor obo:CL_0002152 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002152 "2010-08-24T10:47:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002152 "FMA:86486")
AnnotationAssertion(rdfs:label obo:CL_0002152 "columnar cell of endocervix")
EquivalentClasses(obo:CL_0002152 ObjectIntersectionOf(obo:CL_0000146 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012252)))

# Class: obo:CL_0002153 (corneocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002153 "The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002153 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002153 "2010-08-24T10:53:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002153 "BTO:0001943")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002153 "FMA:68650")
AnnotationAssertion(rdfs:label obo:CL_0002153 "corneocyte")
SubClassOf(obo:CL_0002153 obo:CL_0000225)
SubClassOf(obo:CL_0002153 obo:CL_0000311)
SubClassOf(obo:CL_0002153 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002027))
SubClassOf(obo:CL_0002153 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000312))

# Class: obo:CL_0002154 (early promyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0412046911") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002154 "A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages.")
AnnotationAssertion(terms:contributor obo:CL_0002154 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002154 "2010-08-24T03:07:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002154 "FMA:83533")
AnnotationAssertion(rdfs:label obo:CL_0002154 "early promyelocyte")
SubClassOf(obo:CL_0002154 obo:CL_0000836)

# Class: obo:CL_0002155 (echinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002155 "A crenated erythrocyte with 30+ crenations, bumps or spurs that are the result of damage due to age or disease.")
AnnotationAssertion(terms:contributor obo:CL_0002155 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002155 "2010-08-24T03:15:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002155 "FMA:81099")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002155 "burr cell")
AnnotationAssertion(rdfs:label obo:CL_0002155 "echinocyte")
SubClassOf(obo:CL_0002155 obo:CL_0000595)

# Class: obo:CL_0002156 (obo:CL_0002156)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002156 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002156 obo:CL_0000764)
AnnotationAssertion(owl:deprecated obo:CL_0002156 "true"^^xsd:boolean)

# Class: obo:CL_0002157 (endosteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0618947256") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002157 "A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones.")
AnnotationAssertion(terms:contributor obo:CL_0002157 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002157 "2010-08-24T03:33:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002157 "FMA:86495")
AnnotationAssertion(rdfs:label obo:CL_0002157 "endosteal cell")
SubClassOf(obo:CL_0002157 obo:CL_0002078)
SubClassOf(obo:CL_0002157 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009859))

# Class: obo:CL_0002158 (external epithelial cell of tympanic membrane)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:5686391") obo:IAO_0000115 obo:CL_0002158 "Epithelial cell found on the external side of the tympanic membrane")
AnnotationAssertion(terms:contributor obo:CL_0002158 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002158 "2010-08-25T10:25:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002158 "FMA:70558")
AnnotationAssertion(rdfs:label obo:CL_0002158 "external epithelial cell of tympanic membrane")
SubClassOf(obo:CL_0002158 obo:CL_0002159)

# Class: obo:CL_0002159 (general ecto-epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002159 "Epithelial cells derived from general body ectoderm and ectoderm placodes.")
AnnotationAssertion(terms:contributor obo:CL_0002159 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002159 "2010-08-26T08:31:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002159 "FMA:70556")
AnnotationAssertion(rdfs:label obo:CL_0002159 "general ecto-epithelial cell")
SubClassOf(obo:CL_0002159 obo:CL_0002077)

# Class: obo:CL_0002160 (basal external epithelial cell of tympanic membrane)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5686391") obo:IAO_0000115 obo:CL_0002160 "A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions.")
AnnotationAssertion(terms:contributor obo:CL_0002160 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002160 "2010-08-25T10:28:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002160 "basal external epithelial cell of tympanic membrane")
SubClassOf(obo:CL_0002160 obo:CL_0002158)

# Class: obo:CL_0002161 (superficial external epithelial cell of tympanic membrane)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5686391") obo:IAO_0000115 obo:CL_0002161 "A cell type found on the superficial layer of the external side of the tympanic membrane. This cell-type lacks a nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002161 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002161 "2010-08-25T10:28:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002161 "superficial external epithelial cell of tympanic membrane")
SubClassOf(obo:CL_0002161 obo:CL_0002158)

# Class: obo:CL_0002162 (internal epithelial cell of tympanic membrane)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:5686391") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002162 "An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones.")
AnnotationAssertion(terms:contributor obo:CL_0002162 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002162 "2010-08-25T10:49:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002162 "FMA:70626")
AnnotationAssertion(rdfs:label obo:CL_0002162 "internal epithelial cell of tympanic membrane")
SubClassOf(obo:CL_0002162 obo:CL_0002076)
SubClassOf(obo:CL_0002162 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002364))

# Class: obo:CL_0002163 (internal pillar cell of cochlea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.theodora.com/anatomy/the_internal_ear_or_labyrinth.html") obo:IAO_0000115 obo:CL_0002163 "A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells.")
AnnotationAssertion(terms:contributor obo:CL_0002163 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002163 "2010-08-25T11:05:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002163 "FMA:75726")
AnnotationAssertion(rdfs:label obo:CL_0002163 "internal pillar cell of cochlea")
SubClassOf(obo:CL_0002163 obo:CL_1000191)

# Class: obo:CL_0002164 (external pillar cell of cochlea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.theodora.com/anatomy/the_internal_ear_or_labyrinth.html") obo:IAO_0000115 obo:CL_0002164 "A rod-shaped cell found in 3 or 4 rows that lie adjacent to and support the outer hair cells.")
AnnotationAssertion(terms:contributor obo:CL_0002164 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002164 "2010-08-25T11:05:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002164 "FMA:75727")
AnnotationAssertion(rdfs:label obo:CL_0002164 "external pillar cell of cochlea")
SubClassOf(obo:CL_0002164 obo:CL_1000191)

# Class: obo:CL_0002165 (phalangeal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002165 "A supporting cell that is attached to the basement membrane and forms rows that support the hair cells.")
AnnotationAssertion(terms:contributor obo:CL_0002165 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002165 "2010-08-25T01:29:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002165 "FMA:79800")
AnnotationAssertion(rdfs:label obo:CL_0002165 "phalangeal cell")
SubClassOf(obo:CL_0002165 obo:CL_0002490)

# Class: obo:CL_0002166 (epithelial cell of Malassez)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "ISBN:0815129521") obo:IAO_0000115 obo:CL_0002166 "An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth.")
AnnotationAssertion(terms:contributor obo:CL_0002166 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002166 "2010-08-26T08:51:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002166 "FMA:62987")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002166 "epithelial cell rests of Malassez")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002166 "epithelial debris of Malassez")
AnnotationAssertion(rdfs:label obo:CL_0002166 "epithelial cell of Malassez")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002166 obo:CL_0002159)
SubClassOf(obo:CL_0002166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011595))

# Class: obo:CL_0002167 (olfactory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7143026") obo:IAO_0000115 obo:CL_0002167 "A specialized cell involved in sensory perception of smell.")
AnnotationAssertion(terms:contributor obo:CL_0002167 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002167 "2010-08-26T01:47:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002167 "FMA:67870")
AnnotationAssertion(rdfs:label obo:CL_0002167 "olfactory epithelial cell")
EquivalentClasses(obo:CL_0002167 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
SubClassOf(obo:CL_0002167 obo:CL_0000098)
SubClassOf(obo:CL_0002167 obo:CL_0000710)
SubClassOf(obo:CL_0002167 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050911))

# Class: obo:CL_0002168 (border cell of cochlea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0412046911") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002168 "A border cell is a slender columnar cell on the medial portion of the basilar membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002168 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002168 "2010-08-25T01:47:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002168 "FMA:79798")
AnnotationAssertion(rdfs:label obo:CL_0002168 "border cell of cochlea")
SubClassOf(obo:CL_0002168 obo:CL_0002315)

# Class: obo:CL_0002169 (basal cell of olfactory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7143026") obo:IAO_0000115 obo:CL_0002169 "An epithelial cell located on the basal lamina of the olfactory epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002169 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002169 "2010-08-26T01:58:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002169 "horizontal basal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002169 "FMA:62303")
AnnotationAssertion(rdfs:label obo:CL_0002169 "basal cell of olfactory epithelium")
EquivalentClasses(obo:CL_0002169 ObjectIntersectionOf(obo:CL_0002167 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000482)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002169 obo:CL_0002167)

# Class: obo:CL_0002170 (keratinized cell of the oral mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12014572") obo:IAO_0000115 obo:CL_0002170 "A keratinized cell located in the hard palate or gingiva.")
AnnotationAssertion(terms:contributor obo:CL_0002170 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002170 "2010-08-26T02:51:30Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002170 "keratinized cell of the oral mucosa")
EquivalentClasses(obo:CL_0002170 ObjectIntersectionOf(obo:CL_0000237 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003729)))
SubClassOf(obo:CL_0002170 obo:CL_0000237)
SubClassOf(obo:CL_0002170 obo:CL_0002336)
SubClassOf(obo:CL_0002170 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003729))

# Class: obo:CL_0002171 (globose cell of olfactory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17468753") obo:IAO_0000115 obo:CL_0002171 "A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002171 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002171 "2010-08-26T01:59:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002171 "FMA:67874")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002171 "blastema cell of olfactory epithelium")
AnnotationAssertion(rdfs:label obo:CL_0002171 "globose cell of olfactory epithelium")
SubClassOf(obo:CL_0002171 obo:CL_0002169)

# Class: obo:CL_0002172 (interdental cell of cochlea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0004482") Annotation(oboInOwl:hasDbXref "PMID:2111803") obo:IAO_0000115 obo:CL_0002172 "A long, spindle-shaped supporting cells arranged in parallel rows that secretes components of the tectorial membrane and potassium ions into the endolymph.")
AnnotationAssertion(terms:contributor obo:CL_0002172 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002172 "2010-08-25T02:02:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002172 "FMA:79797")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002172 "interdental cell")
AnnotationAssertion(rdfs:label obo:CL_0002172 "interdental cell of cochlea")
SubClassOf(obo:CL_0002172 obo:CL_0002315)
SubClassOf(obo:CL_0002172 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002276))

# Class: obo:CL_0002173 (extraglomerular mesangial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "http:/www.copewithcytokines.de/cope.cgi?key=Lacis%20cells") obo:IAO_0000115 obo:CL_0002173 "A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_0002173 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002173 "2010-08-25T02:20:55Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002173 "FMA:84143")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002173 "KUPO:0001033")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002173 "Goormaghtigh cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002173 "polar cushion cells")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002173 "lacis cell")
AnnotationAssertion(rdfs:label obo:CL_0002173 "extraglomerular mesangial cell")
EquivalentClasses(obo:CL_0002173 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002321)))
SubClassOf(obo:CL_0002173 obo:CL_0000650)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002173 obo:CL_0002320)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002173 obo:CL_1000618)

# Class: obo:CL_0002174 (follicular cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002174 "A cell within the follicle of an ovary.")
AnnotationAssertion(Annotation(oboInOwl:source <https://github.com/obophenotype/cell-ontology/issues/589>) obo:RO_0002161 obo:CL_0002174 obo:NCBITaxon_50557)
AnnotationAssertion(terms:contributor obo:CL_0002174 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002174 "2010-08-25T03:01:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002174 "EMAPA:31247")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002174 "FMA:70589")
AnnotationAssertion(rdfs:label obo:CL_0002174 "follicular cell of ovary")
EquivalentClasses(obo:CL_0002174 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001305)))

# Class: obo:CL_0002175 (primary follicular cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002175 "A cell within the primary follicle of the ovary.")
AnnotationAssertion(terms:contributor obo:CL_0002175 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002175 "2010-08-25T03:03:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002175 "FMA:70590")
AnnotationAssertion(rdfs:label obo:CL_0002175 "primary follicular cell of ovary")
SubClassOf(obo:CL_0002175 obo:CL_0002174)

# Class: obo:CL_0002176 (secondary follicular cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002176 "A cell of a secondary follicile within the ovary.")
AnnotationAssertion(terms:contributor obo:CL_0002176 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002176 "2010-08-25T03:03:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002176 "FMA:70591")
AnnotationAssertion(rdfs:label obo:CL_0002176 "secondary follicular cell of ovary")
SubClassOf(obo:CL_0002176 obo:CL_0002174)

# Class: obo:CL_0002177 (folliculostellate cell of pars distalis of adenohypophysis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002177 "A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature.")
AnnotationAssertion(terms:contributor obo:CL_0002177 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002177 "2010-08-25T03:10:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002177 "FMA:83102")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002177 "folliculostellate cell of pars anterior of adenohypophysis")
AnnotationAssertion(rdfs:label obo:CL_0002177 "folliculostellate cell of pars distalis of adenohypophysis")
EquivalentClasses(obo:CL_0002177 ObjectIntersectionOf(obo:CL_0000642 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006964)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002177 obo:CL_0000642)
SubClassOf(obo:CL_0002177 obo:CL_0000710)

# Class: obo:CL_0002178 (epithelial cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002178 "An epithelial cell found in the lining of the stomach.")
AnnotationAssertion(terms:contributor obo:CL_0002178 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002178 "2010-08-25T03:22:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002178 "FMA:62948")
AnnotationAssertion(rdfs:label obo:CL_0002178 "epithelial cell of stomach")
EquivalentClasses(obo:CL_0002178 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002178 obo:CL_0002251)

# Class: obo:CL_0002179 (foveolar cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "Wikipedia:Foveolar_cell") obo:IAO_0000115 obo:CL_0002179 "A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall.")
AnnotationAssertion(terms:contributor obo:CL_0002179 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002179 "2010-08-25T03:23:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002179 "FMA:62949")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002179 "FMA:86552")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002179 "surface mucosal cell of stomach")
AnnotationAssertion(rdfs:label obo:CL_0002179 "foveolar cell of stomach")
SubClassOf(obo:CL_0002179 obo:CL_0000075)
SubClassOf(obo:CL_0002179 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))
SubClassOf(obo:CL_0002179 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_0002180 (mucous cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002180 "An epithelial cell of the stomach. This cell produces mucous.")
AnnotationAssertion(terms:contributor obo:CL_0002180 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002180 "2010-08-25T03:38:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002180 "FMA:63464")
AnnotationAssertion(rdfs:label obo:CL_0002180 "mucous cell of stomach")
EquivalentClasses(obo:CL_0002180 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254)))

# Class: obo:CL_0002181 (mucous neck cell of gastric gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002181 "A columnar epithelial mucous secreting cell located in the neck of the gastric glands. These cells have numerous apical secretory vesicles containing mucins and a basally displaced nucleus. The mucous they secrete is distinct histochemically from that of the surface mucous cells of stomach.")
AnnotationAssertion(terms:contributor obo:CL_0002181 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(terms:contributor obo:CL_0002181 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_0002181 "2025-02-21T11:14:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002181 "2010-08-25T03:41:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002181 "neck cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002181 "FMA:62954")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002181 "mucous neck cell")
AnnotationAssertion(rdfs:label obo:CL_0002181 "mucous neck cell of gastric gland")
SubClassOf(obo:CL_0002181 obo:CL_0000075)
SubClassOf(obo:CL_0002181 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000325))
SubClassOf(obo:CL_0002181 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0098594))
SubClassOf(obo:CL_0002181 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_0002182 (obsolete surface mucosal cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002182 "OBSOLETE. A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002182 obo:CL_0002179)
AnnotationAssertion(terms:contributor obo:CL_0002182 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002182 "2010-08-25T03:45:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002182 "FMA:62949")
AnnotationAssertion(rdfs:comment obo:CL_0002182 "Duplicate with foveolar cell of stomach")
AnnotationAssertion(rdfs:label obo:CL_0002182 "obsolete surface mucosal cell of stomach")
AnnotationAssertion(owl:deprecated obo:CL_0002182 "true"^^xsd:boolean)

# Class: obo:CL_0002183 (stem cell of gastric gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002183 "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.")
AnnotationAssertion(terms:contributor obo:CL_0002183 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002183 "2010-08-25T03:57:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002183 "FMA:62953")
AnnotationAssertion(rdfs:label obo:CL_0002183 "stem cell of gastric gland")
EquivalentClasses(obo:CL_0002183 ObjectIntersectionOf(obo:CL_0000048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000325)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002183 obo:CL_0000048)
SubClassOf(obo:CL_0002183 obo:CL_0002178)
SubClassOf(obo:CL_0002183 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))

# Class: obo:CL_0002184 (basal proper cell of olfactory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:0517223651") Annotation(oboInOwl:hasDbXref "PMID:11891623") obo:IAO_0000115 obo:CL_0002184 "A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002184 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002184 "2010-08-26T01:59:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002184 "FMA:62304")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002184 "horizontal basal cells")
AnnotationAssertion(rdfs:label obo:CL_0002184 "basal proper cell of olfactory epithelium")
SubClassOf(obo:CL_0002184 obo:CL_0002169)

# Class: obo:CL_0002185 (obo:CL_0002185)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002185 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002185 obo:CL_0000312)
AnnotationAssertion(owl:deprecated obo:CL_0002185 "true"^^xsd:boolean)

# Class: obo:CL_0002186 (obo:CL_0002186)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002186 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002186 obo:CL_0000649)
AnnotationAssertion(owl:deprecated obo:CL_0002186 "true"^^xsd:boolean)

# Class: obo:CL_0002187 (basal cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:16824012") Annotation(oboInOwl:hasDbXref "PMID:32187560") Annotation(oboInOwl:hasDbXref "WIKIPEDIA:Basal_cell") Annotation(oboInOwl:hasDbXref "doi:/10.1073/pnas.1734203100") obo:IAO_0000115 obo:CL_0002187 "A mitotically active, columnar-shaped keratinocyte located in the stratum basale of the epidermis and attached to the basement membrane. This cell exhibits heterogeneity, encompassing stem and progenitor subpopulations with distinct molecular and proliferative characteristics (Haensel et al., 2020), and serves as the primary source of new keratinocytes for epidermal renewal, homeostasis, and regeneration.")
AnnotationAssertion(terms:contributor obo:CL_0002187 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002187 "2010-08-26T03:12:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002187 "FMA:70571")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32187560") oboInOwl:hasExactSynonym obo:CL_0002187 "epidermal basal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7058342") oboInOwl:hasExactSynonym obo:CL_0002187 "epidermal basal keratinocyte")
AnnotationAssertion(rdfs:label obo:CL_0002187 "basal cell of epidermis")
EquivalentClasses(obo:CL_0002187 ObjectIntersectionOf(obo:CL_0000646 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002025)))
SubClassOf(obo:CL_0002187 obo:CL_0000312)
SubClassOf(obo:CL_0002187 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030216))

# Class: obo:CL_0002188 (glomerular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15840009") obo:IAO_0000115 obo:CL_0002188 "An endothelial cell that is part of the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.")
AnnotationAssertion(terms:contributor obo:CL_0002188 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002188 "2010-08-26T10:59:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002188 "BTO:0004632")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002188 "FMA:70970")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18480313") Annotation(oboInOwl:hasDbXref "PMID:19129259") Annotation(oboInOwl:hasDbXref "PMID:33123011") rdfs:comment obo:CL_0002188 "Glomerular endothelial cells have 60-80 nm fenestrations typically lacking diaphragms in adults but present during embryonic development. Some studies found diaphragms in 2-6% of mature rat glomerular capillaries. Their presence may depend on fixation techniques, developmental stage, or dynamic cell changes. Additionally, these cells help maintain the structural integrity of glomerular capillaries through interactions with the basement membrane and podocytes.")
AnnotationAssertion(rdfs:label obo:CL_0002188 "glomerular endothelial cell")
EquivalentClasses(obo:CL_0002188 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000074)))
SubClassOf(obo:CL_0002188 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0036053))
SubClassOf(obo:CL_0002188 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_0002189 (granular cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:1416031855") Annotation(oboInOwl:hasDbXref "PMID:29262154") Annotation(oboInOwl:hasDbXref "PMID:30355494") Annotation(oboInOwl:hasDbXref "PMID:30725734") Annotation(oboInOwl:hasDbXref "PMID:32843640") Annotation(oboInOwl:hasDbXref "WIKIPEDIA:Stratum_granulosum") obo:IAO_0000115 obo:CL_0002189 "A keratinocyte located in the stratum granulosum of the epidermis, characterized by the presence of keratohyalin granules containing filaggrin—which aggregate keratin filament —and by lamellar granules that secrete lipids and enzymes essential for forming the skin’s waterproof barrier. As these cells progress toward the surface, they adopt a flattened morphology and initiate keratinization to become corneocyte and form the protective stratum corneum. In human epidermis, granular keratinocytes are transcriptomically distinguished by high expression of differentiation markers such as DSC1, KRT2, IVL, and TGM3 (Wang et al., 2020), and LOR, FLG, and SPINK5 (Cheng et al., 2018).")
AnnotationAssertion(terms:contributor obo:CL_0002189 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002189 "2010-08-26T03:19:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002189 "FMA:70543")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32843640") oboInOwl:hasExactSynonym obo:CL_0002189 "granular keratinocyte")
AnnotationAssertion(rdfs:label obo:CL_0002189 "granular cell of epidermis")
SubClassOf(obo:CL_0002189 obo:CL_0000312)
SubClassOf(obo:CL_0002189 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002069))
SubClassOf(obo:CL_0002189 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0036457))
SubClassOf(obo:CL_0002189 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0097209))

# Class: obo:CL_0002190 (squamous cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002190 "A flat keratinocyte immediately below the cornified layer.")
AnnotationAssertion(terms:contributor obo:CL_0002190 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002190 "2010-08-26T03:37:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002190 "FMA:86925")
AnnotationAssertion(rdfs:label obo:CL_0002190 "squamous cell of epidermis")
SubClassOf(obo:CL_0002190 obo:CL_0000312)
SubClassOf(obo:CL_0002190 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))

# Class: obo:CL_0002191 (granulocytopoietic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002191 "A cell involved in the formation of a granulocyte.")
AnnotationAssertion(terms:contributor obo:CL_0002191 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002191 "2010-08-30T12:54:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002191 "FMA:83519")
AnnotationAssertion(rdfs:label obo:CL_0002191 "granulocytopoietic cell")
EquivalentClasses(obo:CL_0002191 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030851)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002191 obo:CL_0000839)

# Class: obo:CL_0002192 (metamyelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Metamyelocyte") obo:IAO_0000115 obo:CL_0002192 "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare.")
AnnotationAssertion(terms:contributor obo:CL_0002192 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002192 "2010-08-30T01:08:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002192 "FMA:83541")
AnnotationAssertion(rdfs:label obo:CL_0002192 "metamyelocyte")
SubClassOf(obo:CL_0002192 obo:CL_0002191)
SubClassOf(obo:CL_0002192 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002193))

# Class: obo:CL_0002193 (myelocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Myelocyte") obo:IAO_0000115 obo:CL_0002193 "A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses.")
AnnotationAssertion(terms:contributor obo:CL_0002193 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002193 "2010-08-30T01:08:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002193 "BTO:0000734")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002193 "FMA:83525")
AnnotationAssertion(rdfs:label obo:CL_0002193 "myelocyte")
SubClassOf(obo:CL_0002193 obo:CL_0002191)
SubClassOf(obo:CL_0002193 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000836))

# Class: obo:CL_0002194 (monopoietic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002194 "A cell involved in the formation of a monocyte (monopoiesis).")
AnnotationAssertion(terms:contributor obo:CL_0002194 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002194 "2010-08-30T01:27:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002194 "FMA:83552")
AnnotationAssertion(rdfs:label obo:CL_0002194 "monopoietic cell")
EquivalentClasses(obo:CL_0002194 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002194 obo:CL_0000839)

# Class: obo:CL_0002195 (hepatic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:26798363") obo:IAO_0000115 obo:CL_0002195 "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes).")
AnnotationAssertion(terms:contributor obo:CL_0002195 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002195 "2010-08-30T02:00:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002195 "FMA:86577")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18442648") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002195 "HpSC")
AnnotationAssertion(rdfs:label obo:CL_0002195 "hepatic stem cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0002195 "https://github.com/obophenotype/cell-ontology/issues/800")
EquivalentClasses(obo:CL_0002195 ObjectIntersectionOf(obo:CL_0000048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002195 obo:CL_0000048)

# Class: obo:CL_0002196 (hepatic oval stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17901986") obo:IAO_0000115 obo:CL_0002196 "A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1038/s12276-020-0483-0>) Annotation(oboInOwl:hasDbXref <https://doi.org/10.3389/fcell.2021.644088>) obo:RO_0004050 obo:CL_0002196 "Liver progenitor cells have been variously named in rodent and human studies as oval cells, hepatic progenitor cells, liver stem cells, ductular reactions, or atypical ductular cells. They were first described as oval cells in rats due to their large nuclear-to-cytoplasm ratio and oval-shaped nuclei. On the difference between 'hepatic liver stem cells' (HLSC) and 'oval cells':  \"... unlike a well-known hepatic progenitor cell population, known as oval cells in rodents, HLSCs do not express CK-7, CK-19, c-kit, CD133 and alpha-smooth muscle actin (α-SMA) (Gaudio et al., 2009)\".")
AnnotationAssertion(terms:contributor obo:CL_0002196 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002196 "2010-08-30T02:01:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002196 "BTO:0004270")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002196 "FMA:86576")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002196 "hepatic oval cell")
AnnotationAssertion(Annotation(terms:contributor <http://orcid.org/0000-0003-1940-6740>) Annotation(oboInOwl:hasDbXref <https://doi.org/10.1038/s12276-020-0483-0>) oboInOwl:hasExactSynonym obo:CL_0002196 "hepatic progenitor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1038/s12276-020-0483-0>) oboInOwl:hasExactSynonym obo:CL_0002196 "liver progenitor cell")
AnnotationAssertion(rdfs:label obo:CL_0002196 "hepatic oval stem cell")
SubClassOf(obo:CL_0002196 obo:CL_0011026)
SubClassOf(obo:CL_0002196 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107))

# Class: obo:CL_0002197 (inactive chief cell of parathyoid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002197 "A parathyroid chief cell that is not actively secreting hormone. Contains small Golgi complexes with only a few grouped vesicles and membrane-bound secretory granules; glycogen and many lipofuscin granules abound but sacs of granular endoplasmic reticulum are rare and dispersed. In normal humans, inactive chief cells out number active chief cells in a ratio of 3-5:1.")
AnnotationAssertion(terms:contributor obo:CL_0002197 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002197 "2010-09-02T11:14:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002197 "inactive chief cell of parathyoid gland")
SubClassOf(obo:CL_0002197 obo:CL_0000446)

# Class: obo:CL_0002198 (oncocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "PMID:20013317") obo:IAO_0000115 obo:CL_0002198 "A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands.")
AnnotationAssertion(terms:contributor obo:CL_0002198 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002198 "2010-09-02T11:26:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002198 "FMA:67606")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002198 "MESH:D024862")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002198 "oxyphil")
AnnotationAssertion(rdfs:label obo:CL_0002198 "oncocyte")
SubClassOf(obo:CL_0002198 obo:CL_0002076)

# Class: obo:CL_0002199 (oxyphil cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20013317") obo:IAO_0000115 obo:CL_0002199 "An oncocyte located in the parathyroid gland.")
AnnotationAssertion(terms:contributor obo:CL_0002199 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002199 "2010-09-02T11:33:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002199 "FMA:69084")
AnnotationAssertion(rdfs:label obo:CL_0002199 "oxyphil cell of parathyroid gland")
SubClassOf(obo:CL_0002199 obo:CL_0002198)
SubClassOf(obo:CL_0002199 obo:CL_0002260)

# Class: obo:CL_0002200 (oxyphil cell of thyroid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20013317") obo:IAO_0000115 obo:CL_0002200 "An oncocyte located in the thyroid.")
AnnotationAssertion(terms:contributor obo:CL_0002200 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002200 "2010-09-02T11:33:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002200 "FMA:87169")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002200 "Askanazy cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002200 "Hurthle cells")
AnnotationAssertion(rdfs:label obo:CL_0002200 "oxyphil cell of thyroid")
EquivalentClasses(obo:CL_0002200 ObjectIntersectionOf(obo:CL_0002198 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002046)))

# Class: obo:CL_0002201 (renal beta-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11781354") Annotation(oboInOwl:hasDbXref "PMID:25632105") obo:IAO_0000115 obo:CL_0002201 "A renal intercalated cell that secretes base and reabsorbs acid in the distal segments of the kidney tubule to maintain acid/base balance.")
AnnotationAssertion(terms:contributor obo:CL_0002201 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002201 "2010-09-02T01:43:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") oboInOwl:hasExactSynonym obo:CL_0002201 "type B intercalated cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") oboInOwl:hasExactSynonym obo:CL_0002201 "type B-IC")
AnnotationAssertion(rdfs:label obo:CL_0002201 "renal beta-intercalated cell")
SubClassOf(obo:CL_0002201 obo:CL_0005010)

# Class: obo:CL_0002202 (epithelial cell of tracheobronchial tree)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002202 "An epithelial cell of the tracheobronchial tree.")
AnnotationAssertion(terms:contributor obo:CL_0002202 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002202 "2010-09-02T02:09:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002202 "FMA:66816")
AnnotationAssertion(rdfs:label obo:CL_0002202 "epithelial cell of tracheobronchial tree")
EquivalentClasses(obo:CL_0002202 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008397)))

# Class: obo:CL_0002203 (tuft cell of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:35271673") obo:IAO_0000115 obo:CL_0002203 "A tuft cell that is part of the epithelium of large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002203 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002203 "2010-09-02T02:20:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002203 "FMA:263222")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002203 "brush cell of epithelium proper of large intestine")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") oboInOwl:hasExactSynonym obo:CL_0002203 "brush cell of large intestine")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") oboInOwl:hasExactSynonym obo:CL_0002203 "tuft cell of epithelium of large intestine")
AnnotationAssertion(rdfs:comment obo:CL_0002203 "Brush cells are a distinct cell type from brush border cell-types.")
AnnotationAssertion(rdfs:label obo:CL_0002203 "tuft cell of large intestine")
EquivalentClasses(obo:CL_0002203 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278)))

# Class: obo:CL_0002204 (tuft cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15817800") Annotation(oboInOwl:hasDbXref "PMID:30379593") Annotation(oboInOwl:hasDbXref "PMID:36704202") obo:IAO_0000115 obo:CL_0002204 "An epithelial cell found in various organs, including the gastrointestinal and respiratory tracts, characterized by a tuft of 120-140 blunt microvilli on its apical surface. This cell exhibits diverse functions depending on its location, which includes chemosensation, initiation of immune responses, contribution to mucociliary clearance, and defense against parasites.")
AnnotationAssertion(terms:contributor obo:CL_0002204 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002204 "2010-09-02T02:28:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002204 "FMA:67978")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36704202") oboInOwl:hasExactSynonym obo:CL_0002204 "brush cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36704202") oboInOwl:hasExactSynonym obo:CL_0002204 "caveolated cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36704202") oboInOwl:hasExactSynonym obo:CL_0002204 "fibrillovesicular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32307399") oboInOwl:hasExactSynonym obo:CL_0002204 "multivesicular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36704202") oboInOwl:hasExactSynonym obo:CL_0002204 "peculiar cell")
AnnotationAssertion(rdfs:label obo:CL_0002204 "tuft cell")
EquivalentClasses(obo:CL_0002204 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0151001)))

# Class: obo:CL_0002205 (brush cell of lobular bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002205 "A brush cell found in the epithelium of lobular bronchiole.")
AnnotationAssertion(terms:contributor obo:CL_0002205 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002205 "2010-09-02T02:38:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002205 "FMA:263220")
AnnotationAssertion(rdfs:label obo:CL_0002205 "brush cell of lobular bronchiole")
EquivalentClasses(obo:CL_0002205 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600001)))

# Class: obo:CL_0002206 (brush cell of terminal bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002206 "A brush cell of the epithelium in the terminal bronchiole.")
AnnotationAssertion(terms:contributor obo:CL_0002206 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002206 "2010-09-02T02:38:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002206 "FMA:263228")
AnnotationAssertion(rdfs:label obo:CL_0002206 "brush cell of terminal bronchiole")
EquivalentClasses(obo:CL_0002206 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001958)))

# Class: obo:CL_0002207 (brush cell of trachea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002207 "Brush cell of the epithelium in the trachea.")
AnnotationAssertion(terms:contributor obo:CL_0002207 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002207 "2010-09-02T02:38:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002207 "FMA:263224")
AnnotationAssertion(rdfs:label obo:CL_0002207 "brush cell of trachea")
EquivalentClasses(obo:CL_0002207 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001901)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002207 obo:CL_0000307)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002207 obo:CL_0002075)

# Class: obo:CL_0002208 (brush cell of bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002208 "A brush cell found in the epithelium of bronchus.")
AnnotationAssertion(terms:contributor obo:CL_0002208 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002208 "2010-09-02T02:38:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002208 "FMA:263226")
AnnotationAssertion(rdfs:label obo:CL_0002208 "brush cell of bronchus")
EquivalentClasses(obo:CL_0002208 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031)))

# Class: obo:CL_0002209 (intermediate epitheliocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002209 "An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells.")
AnnotationAssertion(terms:contributor obo:CL_0002209 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002209 "2010-09-02T02:53:59Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002209 "FMA:69060")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002209 "undifferentiated columnar cell of tracheobronchial tree")
AnnotationAssertion(rdfs:label obo:CL_0002209 "intermediate epitheliocyte")
SubClassOf(obo:CL_0002209 obo:CL_0002202)

# Class: obo:CL_0002210 (red muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002210 "A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance.")
AnnotationAssertion(terms:contributor obo:CL_0002210 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002210 "2010-09-02T03:20:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002210 "FMA:84448")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002210 "oxidative muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002210 "red muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002210 "red muscle cell")
SubClassOf(obo:CL_0002210 obo:CL_0008046)

# Class: obo:CL_0002211 (type I muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002211 "A slow muscle cell that has large amounts of myoglobin, stores energy as triglycerides, generates ATP by the oxidative method and is resistant to fatigue.")
AnnotationAssertion(terms:contributor obo:CL_0002211 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002211 "2010-09-02T03:24:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002211 "BTO:0001812")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002211 "CALOHA:TS-0940")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002211 "FMA:84413")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002211 "slow twitch fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002211 "slow twitch muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D018657") oboInOwl:hasExactSynonym obo:CL_0002211 "slow twitch muscle fiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D018657") oboInOwl:hasExactSynonym obo:CL_0002211 "slow-twitch muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002211 "type 1 muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002211 "type 1 muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002211 "type I muscle fiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D018657") oboInOwl:hasRelatedSynonym obo:CL_0002211 "intermediate muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002211 "type I muscle cell")
SubClassOf(obo:CL_0002211 obo:CL_0000189)
SubClassOf(obo:CL_0002211 obo:CL_0002210)

# Class: obo:CL_0002212 (type II muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002212 "A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate.")
AnnotationAssertion(terms:contributor obo:CL_0002212 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002212 "2010-09-02T03:28:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002212 "BTO:0001813")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002212 "FMA:84414")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002212 "type 2 muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002212 "type 2 muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002212 "type II muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002212 "type II muscle cell")
SubClassOf(obo:CL_0002212 obo:CL_0000190)

# Class: obo:CL_0002213 (white muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002213 "A muscle cell with low content of myoglobin and other oxygen storing proteins. This muscle cell has a white appearance.")
AnnotationAssertion(terms:contributor obo:CL_0002213 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002213 "2010-09-02T03:28:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002213 "FMA:84449")
AnnotationAssertion(rdfs:label obo:CL_0002213 "white muscle cell")
SubClassOf(obo:CL_0002213 obo:CL_0000190)

# Class: obo:CL_0002214 (type IIa muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002214 "A type II muscle cell that contains large amounts of myoglobin, has many mitochondria and very many blood capillaries. Type II A cells are red, have a very high capacity for generating ATP by oxidative metabolic processes, split ATP at a very rapid rate, have a fast contraction velocity and are resistant to fatigue.")
AnnotationAssertion(terms:contributor obo:CL_0002214 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002214 "2010-09-02T03:31:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002214 "BTO:0001813")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002214 "FMA:84415")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002214 "fast twitch A")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002214 "fatigue resistant fast twitch muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002214 "type 2a muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002214 "type 2a muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002214 "type IIa muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002214 "type IIa muscle cell")
SubClassOf(obo:CL_0002214 obo:CL_0002210)
SubClassOf(obo:CL_0002214 obo:CL_0002212)

# Class: obo:CL_0002215 (type IIb muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Skeletal_muscle") obo:IAO_0000115 obo:CL_0002215 "A type II muscle cell that contains a low content of myoglobin, relatively few mitochondria, relatively few blood capillaries and large amounts of glycogen. Type II B fibres are white, geared to generate ATP by anaerobic metabolic processes, not able to supply skeletal muscle fibres continuously with sufficient ATP, fatigue easily, split ATP at a fast rate and have a fast contraction velocity.")
AnnotationAssertion(terms:contributor obo:CL_0002215 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002215 "2010-09-02T03:31:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002215 "FMA:84416")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002215 "type 2b muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002215 "type 2b muscle fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002215 "type IIb muscle fiber")
AnnotationAssertion(rdfs:label obo:CL_0002215 "type IIb muscle cell")
SubClassOf(obo:CL_0002215 obo:CL_0002212)
SubClassOf(obo:CL_0002215 obo:CL_0002213)

# Class: obo:CL_0002216 (intermediate muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002216 "An intermediate muscle cell that has characteristics of both fast and slow muscle cells.")
AnnotationAssertion(terms:contributor obo:CL_0002216 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002216 "2010-09-02T03:51:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002216 "FMA:84450")
AnnotationAssertion(rdfs:label obo:CL_0002216 "intermediate muscle cell")
SubClassOf(obo:CL_0002216 obo:CL_0008046)

# Class: obo:CL_0002217 (intermediate trophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.med.yale.edu/obgyn/kliman/placenta/articles/EOR_Placenta/Trophtoplacenta.html") obo:IAO_0000115 obo:CL_0002217 "A trophoblast that leaves the placenta and invades the endometrium and myometrium. This cell type is crucial in increasing blood flow to the fetus.")
AnnotationAssertion(terms:contributor obo:CL_0002217 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002217 "2010-09-02T04:04:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002217 "BTO:0002366")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002217 "FMA:86564")
AnnotationAssertion(rdfs:label obo:CL_0002217 "intermediate trophoblast cell")
SubClassOf(obo:CL_0002217 obo:CL_0000351)

# Class: obo:CL_0002218 (immature dendritic epithelial T cell precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org") obo:IAO_0000115 obo:CL_0002218 "A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18.")
AnnotationAssertion(terms:contributor obo:CL_0002218 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002218 "2010-10-07T01:58:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002218 "immature DEC precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002218 "immature DETC precursor")
AnnotationAssertion(rdfs:comment obo:CL_0002218 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002218 "immature dendritic epithelial T cell precursor")
SubClassOf(obo:CL_0002218 obo:CL_0002404)

# Class: obo:CL_0002219 (anchoring trophoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.med.yale.edu/obgyn/kliman/placenta/articles/EOR_Placenta/Trophtoplacenta.html") obo:IAO_0000115 obo:CL_0002219 "A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua.")
AnnotationAssertion(terms:contributor obo:CL_0002219 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002219 "2010-09-02T04:14:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002219 "anchoring trophoblast")
SubClassOf(obo:CL_0002219 obo:CL_0000351)

# Class: obo:CL_0002220 (interstitial cell of pineal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002220 "A cell located between the pinealocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002220 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002220 "2010-09-02T04:28:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002220 "FMA:86575")
AnnotationAssertion(rdfs:label obo:CL_0002220 "interstitial cell of pineal gland")
SubClassOf(obo:CL_0002220 obo:CL_0000710)

# Class: obo:CL_0002221 (keratinized squamous cell of esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11694559") obo:IAO_0000115 obo:CL_0002221 "A squamous cell that has keratin in the esophagus.")
AnnotationAssertion(terms:contributor obo:CL_0002221 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002221 "2010-09-07T10:11:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002221 "FMA:86549")
AnnotationAssertion(rdfs:label obo:CL_0002221 "keratinized squamous cell of esophagus")
SubClassOf(obo:CL_0002221 obo:CL_0000237)
SubClassOf(obo:CL_0002221 obo:CL_0002252)
SubClassOf(obo:CL_0002221 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976))

# Class: obo:CL_0002222 (vertebrate lens cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002222 "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye.")
AnnotationAssertion(terms:contributor obo:CL_0002222 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002222 "2010-09-07T10:38:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002222 "FMA:70950")
AnnotationAssertion(rdfs:label obo:CL_0002222 "vertebrate lens cell")
SubClassOf(obo:CL_0002222 obo:CL_0000066)
SubClassOf(obo:CL_0002222 obo:CL_0000306)
SubClassOf(obo:CL_0002222 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000965))

# Class: obo:CL_0002223 (anterior lens cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002223 "A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s).")
AnnotationAssertion(terms:contributor obo:CL_0002223 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002223 "2010-09-07T10:45:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002223 "FMA:63181")
AnnotationAssertion(rdfs:label obo:CL_0002223 "anterior lens cell")
SubClassOf(obo:CL_0002223 obo:CL_0002224)

# Class: obo:CL_0002224 (lens epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium") obo:IAO_0000115 obo:CL_0002224 "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.")
AnnotationAssertion(terms:contributor obo:CL_0002224 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002224 "2010-09-07T10:45:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002224 "FMA:67559")
AnnotationAssertion(rdfs:label obo:CL_0002224 "lens epithelial cell")
EquivalentClasses(obo:CL_0002224 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001803)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002224 obo:CL_0000075)
SubClassOf(obo:CL_0002224 obo:CL_0002222)

# Class: obo:CL_0002225 (secondary lens fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002225 "A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded.")
AnnotationAssertion(terms:contributor obo:CL_0002225 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002225 "2010-09-07T10:53:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002225 "secondary lens fibre")
AnnotationAssertion(rdfs:label obo:CL_0002225 "secondary lens fiber")
SubClassOf(obo:CL_0002225 obo:CL_0011004)
SubClassOf(obo:CL_0002225 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002228))

# Class: obo:CL_0002226 (non-nucleated secondary lens fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002226 "A secondary lens fiber cell that lacks a nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002226 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002226 "2010-09-07T11:15:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002226 "FMA:67561")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002226 "non-nucleated secondary lens fibre")
AnnotationAssertion(rdfs:label obo:CL_0002226 "non-nucleated secondary lens fiber")
SubClassOf(obo:CL_0002226 obo:CL_0002225)
SubClassOf(obo:CL_0002226 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002227))

# Class: obo:CL_0002227 (nucleated secondary lens fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002227 "A secondary fiber cell that contains a nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002227 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002227 "2010-09-07T11:15:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002227 "FMA:70949")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002227 "nucleated secondary lens fibre")
AnnotationAssertion(rdfs:label obo:CL_0002227 "nucleated secondary lens fiber")
SubClassOf(obo:CL_0002227 obo:CL_0002225)

# Class: obo:CL_0002228 (primary lens fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:10711704") obo:IAO_0000115 obo:CL_0002228 "An elongating cell that rapidly obliterates the lumen of the lens vesicle. Subsequently, differentiation of this cell type at the lens equator leads to the formation of secondary fiber cells that come to overlie the primary fibers.")
AnnotationAssertion(terms:contributor obo:CL_0002228 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002228 "2010-09-07T11:19:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002228 "FMA:70613")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002228 "primary lens fibre")
AnnotationAssertion(rdfs:label obo:CL_0002228 "primary lens fiber")
SubClassOf(obo:CL_0002228 obo:CL_0011004)
SubClassOf(obo:CL_0002228 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002223))

# Class: obo:CL_0002229 (light chief cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002229 "A chief cell that is bigger than dark chief cells and has a larger and lighter nucleus and a cytoplasm with few granules.")
AnnotationAssertion(terms:contributor obo:CL_0002229 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002229 "2010-09-07T11:46:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002229 "FMA:69079")
AnnotationAssertion(rdfs:label obo:CL_0002229 "light chief cell of parathyroid gland")
SubClassOf(obo:CL_0002229 obo:CL_0000446)

# Class: obo:CL_0002230 (obo:CL_0002230)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002230 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002230 obo:CL_0002325)
AnnotationAssertion(owl:deprecated obo:CL_0002230 "true"^^xsd:boolean)

# Class: obo:CL_0002231 (epithelial cell of prostate)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002231 "An epithelial cell of the prostate.")
AnnotationAssertion(terms:contributor obo:CL_0002231 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002231 "2010-09-07T01:49:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002231 "FMA:256163")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002231 "FMA:66817")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002231 "prostate epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002231 "epithelial cell of prostate")
EquivalentClasses(obo:CL_0002231 ObjectIntersectionOf(obo:CL_0002076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002231 obo:CL_0002076)

# Class: obo:CL_0002232 (epithelial cell of prostatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002232 "An epithelial cell of prostatic duct.")
AnnotationAssertion(terms:contributor obo:CL_0002232 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002232 "2010-09-07T01:55:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002232 "FMA:74224")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:74224") oboInOwl:hasExactSynonym obo:CL_0002232 "ductal epithelial cell of prostate")
AnnotationAssertion(rdfs:label obo:CL_0002232 "epithelial cell of prostatic duct")
EquivalentClasses(obo:CL_0002232 ObjectIntersectionOf(obo:CL_0000072 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002485)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002232 obo:CL_0000072)
SubClassOf(obo:CL_0002232 obo:CL_0002231)

# Class: obo:CL_0002233 (epithelial cell of prostatic acinus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC2673349") obo:IAO_0000115 obo:CL_0002233 "An epithelial cell of the prostatic acinus.")
AnnotationAssertion(terms:contributor obo:CL_0002233 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002233 "2010-09-07T01:55:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002233 "FMA:74223")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:74223") oboInOwl:hasExactSynonym obo:CL_0002233 "acinar epithelial cell of prostate")
AnnotationAssertion(rdfs:label obo:CL_0002233 "epithelial cell of prostatic acinus")
EquivalentClasses(obo:CL_0002233 ObjectIntersectionOf(obo:CL_0002231 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004179)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002233 obo:CL_0002231)

# Class: obo:CL_0002234 (basal cell of prostatic acinus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002234 "A cell of the basal layer of the epithelium in the prostatic acinus.")
AnnotationAssertion(terms:contributor obo:CL_0002234 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002234 "2010-09-07T01:59:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002234 "FMA:74265")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:74265") oboInOwl:hasExactSynonym obo:CL_0002234 "basal epithelial cell of prostatic acinus")
AnnotationAssertion(rdfs:label obo:CL_0002234 "basal cell of prostatic acinus")
EquivalentClasses(obo:CL_0002234 ObjectIntersectionOf(obo:CL_0002341 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004179)))

# Class: obo:CL_0002235 (luminal cell of prostatic acinus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002235 "A cell of the luminal layer of the epithelium in the prostatic acinus.")
AnnotationAssertion(terms:contributor obo:CL_0002235 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002235 "2010-09-07T01:59:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002235 "FMA:74266")
AnnotationAssertion(rdfs:label obo:CL_0002235 "luminal cell of prostatic acinus")
EquivalentClasses(obo:CL_0002235 ObjectIntersectionOf(obo:CL_0002340 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004179)))

# Class: obo:CL_0002236 (basal epithelial cell of prostatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15226377") obo:IAO_0000115 obo:CL_0002236 "A cell that constitutes the basal layer of epithelium in the prostatic duct.")
AnnotationAssertion(terms:contributor obo:CL_0002236 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002236 "2010-09-07T01:59:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002236 "FMA:74226")
AnnotationAssertion(rdfs:label obo:CL_0002236 "basal epithelial cell of prostatic duct")
EquivalentClasses(obo:CL_0002236 ObjectIntersectionOf(obo:CL_0002341 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002485)))

# Class: obo:CL_0002237 (luminal epithelial cell of prostatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002237 "A cell that constitutes the luminal layer of epithelium of prostatic duct.")
AnnotationAssertion(terms:contributor obo:CL_0002237 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002237 "2010-09-07T01:59:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002237 "FMA:74225")
AnnotationAssertion(rdfs:label obo:CL_0002237 "luminal epithelial cell of prostatic duct")
EquivalentClasses(obo:CL_0002237 ObjectIntersectionOf(obo:CL_0002340 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002485)))

# Class: obo:CL_0002238 (male gonocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002238 "A primordial germ cell that is destined to become a male germ cell.")
AnnotationAssertion(terms:contributor obo:CL_0002238 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002238 "2010-09-07T02:11:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002238 "EHDAA2:0001053")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002238 "EMAPA:18686")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002238 "FMA:84771")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002238 "VHOG:0000662")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002238 "male primordial germ cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VHOG:0000662") oboInOwl:hasExactSynonym obo:CL_0002238 "testis primordial germ cell")
AnnotationAssertion(rdfs:label obo:CL_0002238 "male gonocyte")
SubClassOf(obo:CL_0002238 obo:CL_0000670)
SubClassOf(obo:CL_0002238 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000473))

# Class: obo:CL_0002239 (ooblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002239 "A primordial cell from which an oocyte (ovum) ultimately is developed.")
AnnotationAssertion(terms:contributor obo:CL_0002239 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002239 "2010-09-07T02:11:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002239 "EHDAA2:0000505")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002239 "EMAPA:17965")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002239 "FMA:84772")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002239 "ISBN:0721662544")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002239 "VHOG:0000661")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "VHOG:0000661") oboInOwl:hasExactSynonym obo:CL_0002239 "ovary primordial germ cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:84772") oboInOwl:hasExactSynonym obo:CL_0002239 "ovigerm")
AnnotationAssertion(rdfs:label obo:CL_0002239 "ooblast")
SubClassOf(obo:CL_0002239 obo:CL_0000670)
SubClassOf(obo:CL_0002239 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992))

# Class: obo:CL_0002240 (marrow fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002240 "A fibroblast in the bone marrow.")
AnnotationAssertion(terms:contributor obo:CL_0002240 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002240 "2010-09-07T02:25:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002240 "FMA:84377")
AnnotationAssertion(rdfs:label obo:CL_0002240 "marrow fibroblast")
EquivalentClasses(obo:CL_0002240 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))
SubClassOf(obo:CL_0002240 obo:CL_0000057)

# Class: obo:CL_0002241 (pulmonary interstitial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002241 "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis.")
AnnotationAssertion(terms:contributor obo:CL_0002241 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002241 "2010-09-07T02:29:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002241 "FMA:84467")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002241 "pulmonary myofibroblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002241 "pulmonary septal cell")
AnnotationAssertion(rdfs:label obo:CL_0002241 "pulmonary interstitial fibroblast")
EquivalentClasses(obo:CL_0002241 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001004) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005169)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002241 obo:CL_0000057)

# Class: obo:CL_0002242 (nucleate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002242 "A cell containing at least one nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002242 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002242 "2010-09-07T03:32:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002242 "FMA:67513")
AnnotationAssertion(rdfs:label obo:CL_0002242 "nucleate cell")
EquivalentClasses(obo:CL_0002242 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505)))

# Class: obo:CL_0002243 (smooth muscle cell of sphincter of pupil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") Annotation(oboInOwl:hasDbXref "ISBN:0721694128") obo:IAO_0000115 obo:CL_0002243 "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells.")
AnnotationAssertion(terms:contributor obo:CL_0002243 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002243 "2010-09-08T08:53:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002243 "FMA:70611")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002243 "smooth muscle fiber of sphincter of pupil")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002243 "smooth muscle fibre of sphincter of pupil")
AnnotationAssertion(rdfs:label obo:CL_0002243 "smooth muscle cell of sphincter of pupil")
EquivalentClasses(obo:CL_0002243 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001607)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002243 obo:CL_0000358)
SubClassOf(obo:CL_0002243 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0002244 (squamous cell of ectocervix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:32644501") Annotation(oboInOwl:hasDbXref "doi:/10.1016/j.autneu.2015.04.008") Annotation(oboInOwl:hasDbXref "http://www.bu.edu/histology/p/19404loa.htm") obo:IAO_0000115 obo:CL_0002244 "A stratified squamous epithelial cell located in the ectocervix.")
AnnotationAssertion(terms:contributor obo:CL_0002244 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002244 "2010-09-08T09:12:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002244 "FMA:86483")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002244 "ectocervical squamous cell")
AnnotationAssertion(rdfs:label obo:CL_0002244 "squamous cell of ectocervix")
EquivalentClasses(obo:CL_0002244 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012251)))

# Class: obo:CL_0002245 (obsolete null lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") obo:IAO_0000115 obo:CL_0002245 "OBSOLETE: A lymphocyte that lacks T or B cell surface markers.")
AnnotationAssertion(terms:contributor obo:CL_0002245 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002245 "2010-09-07T03:43:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002245 "FMA:83601")
AnnotationAssertion(rdfs:label obo:CL_0002245 "obsolete null lymphocyte")
AnnotationAssertion(owl:deprecated obo:CL_0002245 "true"^^xsd:boolean)

# Class: obo:CL_0002246 (peripheral blood stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002246 "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells).")
AnnotationAssertion(terms:contributor obo:CL_0002246 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002246 "2010-09-07T03:57:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002246 "BTO:0002669")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002246 "FMA:86711")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002246 "MESH:D000072916")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002246 "PBSC")
AnnotationAssertion(rdfs:label obo:CL_0002246 "peripheral blood stem cell")
EquivalentClasses(obo:CL_0002246 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000178)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002246 obo:CL_0000037)

# Class: obo:CL_0002247 (pleural macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002247 "A tissue macrophage that is in the pleural space.")
AnnotationAssertion(terms:contributor obo:CL_0002247 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002247 "2010-09-07T04:16:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002247 "FMA:83024")
AnnotationAssertion(rdfs:label obo:CL_0002247 "pleural macrophage")
SubClassOf(obo:CL_0002247 obo:CL_0000864)

# Class: obo:CL_0002248 (pluripotent stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19343304") obo:IAO_0000115 obo:CL_0002248 "A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta.")
AnnotationAssertion(terms:contributor obo:CL_0002248 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002248 "2010-09-07T04:26:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002248 "FMA:70570")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002248 "MESH:D039904")
AnnotationAssertion(rdfs:label obo:CL_0002248 "pluripotent stem cell")
SubClassOf(obo:CL_0002248 obo:CL_0000723)

# Class: obo:CL_0002249 (primitive cardiac myocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16938308") obo:IAO_0000115 obo:CL_0002249 "A stem cell that can differentiate into a cardiac myocyte.")
AnnotationAssertion(terms:contributor obo:CL_0002249 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002249 "2010-09-07T04:40:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002249 "FMA:75620")
AnnotationAssertion(rdfs:label obo:CL_0002249 "primitive cardiac myocyte")
SubClassOf(obo:CL_0002249 obo:CL_0000035)
SubClassOf(obo:CL_0002249 obo:CL_0002078)

# Class: obo:CL_0002250 (intestinal crypt stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002250 "A stem cell located in epithelium the based of the crypt of Lieberkuhn. Division of these cells serve both to maintain the stem cell population and produce the transit amplifying cells that are all precursors of all cell types that populate the intestinal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002250 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002250 "2010-09-08T09:21:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002250 "FMA:63379")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002250 "stem cell of intestinal crypt of Lieberkuhn")
AnnotationAssertion(rdfs:label obo:CL_0002250 "intestinal crypt stem cell")
EquivalentClasses(obo:CL_0002250 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001983)))
SubClassOf(obo:CL_0002250 obo:CL_0000048)
SubClassOf(obo:CL_0002250 obo:CL_0002563)

# Class: obo:CL_0002251 (epithelial cell of alimentary canal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002251 "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.")
AnnotationAssertion(terms:contributor obo:CL_0002251 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002251 "2010-09-08T09:26:53Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002251 "epithelial cell of alimentary canal")
EquivalentClasses(obo:CL_0002251 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003929)))
SubClassOf(obo:CL_0002251 obo:CL_0002076)

# Class: obo:CL_0002252 (epithelial cell of esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002252 "An epithelial cell of the lining of the esophagus.")
AnnotationAssertion(terms:contributor obo:CL_0002252 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002252 "2010-09-08T09:28:20Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002252 "FMA:63071")
AnnotationAssertion(rdfs:label obo:CL_0002252 "epithelial cell of esophagus")
EquivalentClasses(obo:CL_0002252 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002252 obo:CL_0002251)

# Class: obo:CL_0002253 (epithelial cell of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002253 "An epithelial cell of the lining of the large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002253 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002253 "2010-09-08T09:28:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002253 "BTO:0004297")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002253 "FMA:256157")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002253 "epithelial cell of colon")
AnnotationAssertion(rdfs:label obo:CL_0002253 "epithelial cell of large intestine")
EquivalentClasses(obo:CL_0002253 ObjectIntersectionOf(obo:CL_0002563 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000059)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002253 obo:CL_0002563)
SubClassOf(obo:CL_0002253 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_0002254 (epithelial cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002254 "An epithelial cell of the lining of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002254 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002254 "2010-09-08T09:41:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002254 "FMA:256159")
AnnotationAssertion(rdfs:label obo:CL_0002254 "epithelial cell of small intestine")
EquivalentClasses(obo:CL_0002254 ObjectIntersectionOf(obo:CL_0002563 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002254 obo:CL_0002563)

# Class: obo:CL_0002255 (stromal cell of endometrium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11331626") Annotation(oboInOwl:hasDbXref "PMID:30013421") Annotation(oboInOwl:hasDbXref "PMID:30309298") Annotation(oboInOwl:hasDbXref "PMID:31907034") Annotation(oboInOwl:hasDbXref "Wikipedia:Decidualization") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1038/s41591-020-1040-z") obo:IAO_0000115 obo:CL_0002255 "A stromal cell of the endometrium, characterized by its fibroblast-like morphology, regenerative capacity, and ability to undergo decidualization. It differentiates into a decidual stromal cell during pregnancy, essential for embryo implantation and maintenance. This cell is involved in tissue proliferation, remodeling, and breakdown, responding to hormonal changes, particularly estrogen and progesterone.")
AnnotationAssertion(terms:contributor obo:CL_0002255 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002255 "2010-09-08T09:50:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002255 "stromal cell of uterus")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002255 "CALOHA:TS-1266")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002255 "FMA:86490")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002255 "endometrial stromal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30309298") oboInOwl:hasExactSynonym obo:CL_0002255 "endometrial stromal fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0002255 "stromal cell of endometrium")
EquivalentClasses(obo:CL_0002255 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002337)))
SubClassOf(obo:CL_0002255 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046697))
SubClassOf(obo:CL_0002255 ObjectSomeValuesFrom(obo:RO_0002388 obo:CL_2000002))

# Class: obo:CL_0002256 (supporting cell of carotid body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:8985136") Annotation(oboInOwl:hasDbXref "http://www.copewithcytokines.de/cope.cgi?key=glomus%20cells") obo:IAO_0000115 obo:CL_0002256 "A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings.")
AnnotationAssertion(terms:contributor obo:CL_0002256 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002256 "2010-09-08T10:34:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002256 "FMA:84188")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002256 "carotid body sustentacular cell")
AnnotationAssertion(rdfs:label obo:CL_0002256 "supporting cell of carotid body")
SubClassOf(obo:CL_0002256 obo:CL_0000630)
SubClassOf(obo:CL_0002256 obo:CL_0000710)

# Class: obo:CL_0002257 (epithelial cell of thyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002257 "An epithelial cell of thyroid gland.")
AnnotationAssertion(terms:contributor obo:CL_0002257 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002257 "2010-09-08T01:46:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002257 "FMA:256167")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002257 "MESH:D000072637")
AnnotationAssertion(rdfs:label obo:CL_0002257 "epithelial cell of thyroid gland")
EquivalentClasses(obo:CL_0002257 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002046)))
SubClassOf(obo:CL_0002257 obo:CL_0000150)
SubClassOf(obo:CL_0002257 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000223))

# Class: obo:CL_0002258 (thyroid follicular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:31869123") obo:IAO_0000115 obo:CL_0002258 "An epithelial cell that is part of the thyroid follicle epithelium, with a shape that ranges from squamous when inactive to cuboidal or columnar when active, reflecting its hormonal activity. Its apical surface is lined with microvilli projecting into the colloid-filled lumen, where it synthesizes, stores, and secretes the thyroid hormones thyroxine (T4) and triiodothyronine (T3), releasing them into the bloodstream in response to thyroid-stimulating hormone (TSH).")
AnnotationAssertion(terms:contributor obo:CL_0002258 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(terms:contributor obo:CL_0002258 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002258 "2010-09-08T01:50:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002258 "BTO:0003736")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002258 "CALOHA:TS-1285")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002258 "FMA:68782")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002258 "follicular cell of thyroid gland")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002258 "principal cell of thyroid gland")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002258 "thyroid gland follicular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002258 "thyroid hormone secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0002258 "thyroid follicular cell")
EquivalentClasses(obo:CL_0002258 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012363) ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0070460 ObjectSomeValuesFrom(obo:RO_0002339 obo:UBERON_0001009)))))
SubClassOf(obo:CL_0002258 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))

# Class: obo:CL_0002259 (neuroepithelial stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11687496") obo:IAO_0000115 obo:CL_0002259 "The stem cell from which glial precursor cell arises from.")
AnnotationAssertion(terms:contributor obo:CL_0002259 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002259 "2010-09-08T02:14:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002259 "FMA:87171")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0002259 "totipotent neuroepithelial stem cell")
AnnotationAssertion(rdfs:label obo:CL_0002259 "neuroepithelial stem cell")
SubClassOf(obo:CL_0002259 obo:CL_0000723)

# Class: obo:CL_0002260 (epithelial cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002260 "An epithelial cell of the parathyroid gland.")
AnnotationAssertion(terms:contributor obo:CL_0002260 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002260 "2010-09-08T02:29:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002260 "FMA:70547")
AnnotationAssertion(rdfs:label obo:CL_0002260 "epithelial cell of parathyroid gland")
EquivalentClasses(obo:CL_0002260 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001132)))
SubClassOf(obo:CL_0002260 obo:CL_0002076)

# Class: obo:CL_0002261 (endothelial cell of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002261 "An endothelial cell found in the mucosa associated with the facial skeleton.")
AnnotationAssertion(terms:contributor obo:CL_0002261 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002261 "2010-09-14T10:40:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002261 "FMA:70627")
AnnotationAssertion(rdfs:label obo:CL_0002261 "endothelial cell of viscerocranial mucosa")
SubClassOf(obo:CL_0002261 obo:CL_0002076)

# Class: obo:CL_0002262 (endothelial cell of sinusoid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002262 "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.")
AnnotationAssertion(terms:contributor obo:CL_0002262 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002262 "2010-09-14T10:57:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002262 "FMA:63134")
AnnotationAssertion(rdfs:label obo:CL_0002262 "endothelial cell of sinusoid")
EquivalentClasses(obo:CL_0002262 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003909)))

# Class: obo:CL_0002263 (transitional cell of parathyroid gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") obo:IAO_0000115 obo:CL_0002263 "One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage.")
AnnotationAssertion(terms:contributor obo:CL_0002263 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002263 "2010-09-08T02:33:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002263 "FMA:69324")
AnnotationAssertion(rdfs:label obo:CL_0002263 "transitional cell of parathyroid gland")
SubClassOf(obo:CL_0002263 obo:CL_0002260)

# Class: obo:CL_0002264 (type A cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002264 "A type of enteroendocrine cell found in the stomach that secretes glucagon.")
AnnotationAssertion(terms:contributor obo:CL_0002264 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002264 "2010-09-10T10:54:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002264 "FMA:83411")
AnnotationAssertion(rdfs:label obo:CL_0002264 "type A cell of stomach")
EquivalentClasses(obo:CL_0002264 ObjectIntersectionOf(obo:CL_0002067 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))
SubClassOf(obo:CL_0002264 obo:CL_0002067)

# Class: obo:CL_0002265 (type D cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002265 "A D cell located in the colon.")
AnnotationAssertion(terms:contributor obo:CL_0002265 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002265 "2010-09-10T11:37:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002265 "FMA:268744")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002265 "colon D-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002265 "colonic delta cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002265 "delta cell of colon")
AnnotationAssertion(rdfs:label obo:CL_0002265 "type D cell of colon")
EquivalentClasses(obo:CL_0002265 ObjectIntersectionOf(obo:CL_0000502 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(obo:CL_0002265 obo:CL_0000502)
SubClassOf(obo:CL_0002265 obo:CL_0002658)
SubClassOf(obo:CL_0002265 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397))

# Class: obo:CL_0002266 (type D cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002266 "A type D cell of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002266 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002266 "2010-09-10T01:34:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002266 "FMA:268736")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002266 "delta cell of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002266 "small intestine D-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002266 "small intestine delta cell")
AnnotationAssertion(rdfs:label obo:CL_0002266 "type D cell of small intestine")
EquivalentClasses(obo:CL_0002266 ObjectIntersectionOf(obo:CL_0000502 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(obo:CL_0002266 obo:CL_0002254)
SubClassOf(obo:CL_0002266 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002267 (type D cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002267 "A type D cell found in the stomach.")
AnnotationAssertion(terms:contributor obo:CL_0002267 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002267 "2010-09-10T01:36:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002267 "FMA:83410")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002267 "delta cell of stomach")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002267 "stomach D-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002267 "stomach delta cell")
AnnotationAssertion(rdfs:label obo:CL_0002267 "type D cell of stomach")
EquivalentClasses(obo:CL_0002267 ObjectIntersectionOf(obo:CL_0000502 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))
SubClassOf(obo:CL_0002267 obo:CL_0000502)
SubClassOf(obo:CL_0002267 obo:CL_0002659)
SubClassOf(obo:CL_0002267 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))

# Class: obo:CL_0002268 (P/D1 enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002268 "An enteroendocrine cell that stores and secretes Ghrelin.")
AnnotationAssertion(terms:contributor obo:CL_0002268 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002268 "2010-09-10T01:47:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002268 "FMA:63418")
AnnotationAssertion(rdfs:label obo:CL_0002268 "P/D1 enteroendocrine cell")
SubClassOf(obo:CL_0002268 obo:CL_0000164)
SubClassOf(obo:CL_0002268 obo:CL_0000167)
SubClassOf(obo:CL_0002268 obo:CL_0002269)

# Class: obo:CL_0002269 (vasoactive intestinal peptide secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002269 "An endocrine cell that secretes vasoactive intestinal peptide.")
AnnotationAssertion(terms:contributor obo:CL_0002269 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002269 "2010-09-10T01:52:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002269 "vasoactive intestinal peptide secreting cell")
SubClassOf(obo:CL_0002269 obo:CL_0000167)

# Class: obo:CL_0002270 (type EC2 enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002270 "A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine.")
AnnotationAssertion(terms:contributor obo:CL_0002270 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002270 "2010-09-10T02:13:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002270 "Mo enteroendocrine cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002270 "FMA:62941")
AnnotationAssertion(rdfs:label obo:CL_0002270 "type EC2 enteroendocrine cell")
SubClassOf(obo:CL_0002270 obo:CL_0000458)
SubClassOf(obo:CL_0002270 obo:CL_0000577)
SubClassOf(obo:CL_0002270 obo:CL_0002272)
SubClassOf(obo:CL_0002270 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))

# Class: obo:CL_0002271 (type EC1 enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002271 "A type EC enteredocrine cell in the intestines that stores and secretes substance P and 5-hydroxytryptamine.")
AnnotationAssertion(terms:contributor obo:CL_0002271 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002271 "2010-09-10T02:13:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002271 "FMA:62940")
AnnotationAssertion(rdfs:label obo:CL_0002271 "type EC1 enteroendocrine cell")
SubClassOf(obo:CL_0002271 obo:CL_0000505)
SubClassOf(obo:CL_0002271 obo:CL_0000577)
SubClassOf(obo:CL_0002271 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))

# Class: obo:CL_0002272 (motilin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D009037") obo:IAO_0000115 obo:CL_0002272 "A cell that secretes motilin, a gastric hormone that at low pH inhibits gastric motor activity, whereas at high pH has a stimulating effect.")
AnnotationAssertion(terms:contributor obo:CL_0002272 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002272 "2010-09-10T02:31:13Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002272 "motilin secreting cell")
SubClassOf(obo:CL_0002272 obo:CL_0000167)

# Class: obo:CL_0002273 (type ECL enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002273 "A type EC enteroendocrine cell type that is numerous in the fundus of the stomach; stores 5-hydroxytryptamine and histamine.")
AnnotationAssertion(terms:contributor obo:CL_0002273 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002273 "2010-09-10T02:35:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002273 "FMA:63208")
AnnotationAssertion(rdfs:label obo:CL_0002273 "type ECL enteroendocrine cell")
SubClassOf(obo:CL_0002273 obo:CL_0000458)
SubClassOf(obo:CL_0002273 obo:CL_0000577)
SubClassOf(obo:CL_0002273 obo:CL_0002274)

# Class: obo:CL_0002274 (histamine secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002274 "A cell type that secretes histamine.")
AnnotationAssertion(terms:contributor obo:CL_0002274 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002274 "2010-09-10T03:04:42Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002274 "histamine secreting cell")
EquivalentClasses(obo:CL_0002274 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001821)))
SubClassOf(obo:CL_0002274 obo:CL_0000457)

# Class: obo:CL_0002275 (pancreatic PP cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002275 "A PP cell located in the islets of the pancreas.")
AnnotationAssertion(terms:contributor obo:CL_0002275 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002275 "2010-09-10T03:30:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002275 "BTO:0000805")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002275 "FMA:70588")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002275 "MESH:D050418")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002275 "PP cell of pancreatic islet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002275 "PP-cell of pancreatic islet")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002275 "pancreatic polypeptide-secreting cell")
AnnotationAssertion(rdfs:comment obo:CL_0002275 "The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell.")
AnnotationAssertion(rdfs:label obo:CL_0002275 "pancreatic PP cell")
EquivalentClasses(obo:CL_0002275 ObjectIntersectionOf(obo:CL_0000696 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))

# Class: obo:CL_0002276 (obsolete PP cell of pancreatic acinus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002276 "OBSOLETE: A PP cell located in the pancreatic acinus. Obsoleted due to a lack of published evidence that this cell type is actually found in the pancreatic acinus.")
AnnotationAssertion(terms:contributor obo:CL_0002276 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002276 "2010-09-10T03:30:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002276 "FMA:85400")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002276 "type F cell of pancreatic acinus")
AnnotationAssertion(rdfs:label obo:CL_0002276 "obsolete PP cell of pancreatic acinus")
AnnotationAssertion(owl:deprecated obo:CL_0002276 "true"^^xsd:boolean)

# Class: obo:CL_0002277 (type I enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002277 "An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile.")
AnnotationAssertion(terms:contributor obo:CL_0002277 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002277 "2010-09-10T03:44:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002277 "FMA:62937")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002277 "CCK cell")
AnnotationAssertion(rdfs:label obo:CL_0002277 "type I enteroendocrine cell")
SubClassOf(obo:CL_0002277 obo:CL_0000164)
SubClassOf(obo:CL_0002277 obo:CL_0000167)
SubClassOf(obo:CL_0002277 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002278 (GIP cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002278 "An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide.")
AnnotationAssertion(terms:contributor obo:CL_0002278 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002278 "2010-09-10T03:51:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002278 "FMA:62942")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002278 "type K enteroendocrine cell")
AnnotationAssertion(rdfs:label obo:CL_0002278 "GIP cell")
SubClassOf(obo:CL_0002278 obo:CL_0000164)
SubClassOf(obo:CL_0002278 obo:CL_0000167)
SubClassOf(obo:CL_0002278 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002279 (type L enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002279 "A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY.")
AnnotationAssertion(terms:contributor obo:CL_0002279 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002279 "2010-09-10T03:59:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002279 "FMA:62944")
AnnotationAssertion(rdfs:label obo:CL_0002279 "type L enteroendocrine cell")
SubClassOf(obo:CL_0002279 obo:CL_0000164)
SubClassOf(obo:CL_0002279 obo:CL_0000167)
SubClassOf(obo:CL_0002279 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))

# Class: obo:CL_0002280 (type N enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002280 "An enteroendocrine cell found in the ileum and jejunum that produces neurotensin.")
AnnotationAssertion(terms:contributor obo:CL_0002280 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002280 "2010-09-10T04:08:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002280 "FMA:62943")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002280 "N cell")
AnnotationAssertion(rdfs:label obo:CL_0002280 "type N enteroendocrine cell")
SubClassOf(obo:CL_0002280 obo:CL_0000164)
SubClassOf(obo:CL_0002280 obo:CL_0000167)
SubClassOf(obo:CL_0002280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002281 (type S enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002281 "Scattered in duodenojejunal mucosa, this enteroendocrine cell secretes secretin and serotonin.")
AnnotationAssertion(terms:contributor obo:CL_0002281 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002281 "2010-09-10T04:44:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002281 "FMA:62936")
AnnotationAssertion(rdfs:label obo:CL_0002281 "type S enteroendocrine cell")
SubClassOf(obo:CL_0002281 obo:CL_0000164)
SubClassOf(obo:CL_0002281 obo:CL_0000167)
SubClassOf(obo:CL_0002281 obo:CL_0000458)
SubClassOf(obo:CL_0002281 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002282 (type TG enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1007/978-3-211-99390-3") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:7013499") obo:IAO_0000115 obo:CL_0002282 "An enteroendocrine cell which produces a gastrin- and cholecystokinin-like peptide. The apical microvilli-rich plasma membrane is in open contact with the small intestine mucosa. This cell type is devoid of gastrin-17 but contains other fragments of the gastrin polypeptide.")
AnnotationAssertion(terms:contributor obo:CL_0002282 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002282 "2010-09-13T09:48:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002282 "FMA:63421")
AnnotationAssertion(rdfs:label obo:CL_0002282 "type TG enteroendocrine cell")
SubClassOf(obo:CL_0002282 obo:CL_0000164)
SubClassOf(obo:CL_0002282 obo:CL_0000509)

# Class: obo:CL_0002283 (ecto-epithelial cell of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0002283 "An epithelial cell of the mucosa associated with facial skeleton.")
AnnotationAssertion(terms:contributor obo:CL_0002283 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002283 "2010-09-14T11:04:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002283 "FMA:70581")
AnnotationAssertion(rdfs:label obo:CL_0002283 "ecto-epithelial cell of viscerocranial mucosa")
SubClassOf(obo:CL_0002283 obo:CL_0002159)

# Class: obo:CL_0002284 (type X enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20616512") obo:IAO_0000115 obo:CL_0002284 "An enteroendocrine cell found in the fundus and pylorus; this cell type has dense round secretory granules that contain ghrelin.")
AnnotationAssertion(terms:contributor obo:CL_0002284 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002284 "2010-09-13T10:12:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002284 "FMA:63209")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002284 "A-like")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002284 "X/A-like")
AnnotationAssertion(rdfs:label obo:CL_0002284 "type X enteroendocrine cell")
SubClassOf(obo:CL_0002284 obo:CL_0000164)
SubClassOf(obo:CL_0002284 obo:CL_0005018)

# Class: obo:CL_0002285 (type III taste bud cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15738192") obo:IAO_0000115 obo:CL_0002285 "A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM.")
AnnotationAssertion(terms:contributor obo:CL_0002285 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002285 "2010-09-13T10:57:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002285 "taste bud basal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002285 "FMA:67940")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002285 "type 3 taste cell")
AnnotationAssertion(rdfs:label obo:CL_0002285 "type III taste bud cell")
SubClassOf(obo:CL_0002285 obo:CL_0000048)
SubClassOf(obo:CL_0002285 obo:CL_0000209)

# Class: obo:CL_0002286 (type II taste cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15738192") obo:IAO_0000115 obo:CL_0002286 "A taste receptor cell that has a short microvilli, a projecting apical region, a large rounded nucleus, and expresses taste chemoreceptors thus making them the transducing cell for taste qualities.")
AnnotationAssertion(terms:contributor obo:CL_0002286 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002286 "2010-09-13T10:57:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002286 "FMA:62381")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002286 "type 2 taste cell")
AnnotationAssertion(rdfs:label obo:CL_0002286 "type II taste cell")
SubClassOf(obo:CL_0002286 obo:CL_0000209)

# Class: obo:CL_0002287 (type IV taste receptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15738192") obo:IAO_0000115 obo:CL_0002287 "A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally.")
AnnotationAssertion(terms:contributor obo:CL_0002287 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002287 "2010-09-13T10:57:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002287 "taste bud basal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002287 "FMA:62380")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002287 "type 4 taste cell")
AnnotationAssertion(rdfs:comment obo:CL_0002287 "There is debate about the exact lineage of these cell types from this progenitor. See PMID:15738192.")
AnnotationAssertion(rdfs:label obo:CL_0002287 "type IV taste receptor cell")
SubClassOf(obo:CL_0002287 obo:CL_0000034)
SubClassOf(obo:CL_0002287 obo:CL_0000209)

# Class: obo:CL_0002288 (type V taste receptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002288 "A cell type that forms the boundary with the surrounding epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002288 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002288 "2010-09-13T10:57:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002288 "FMA:67941")
AnnotationAssertion(rdfs:label obo:CL_0002288 "type V taste receptor cell")
SubClassOf(obo:CL_0002288 obo:CL_0000209)

# Class: obo:CL_0002289 (type I taste bud cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:15738192") obo:IAO_0000115 obo:CL_0002289 "A densely staining taste receptor cell that contains many dense vacuoles in their apical regions which project into the apical space and bear microvilli. This cell type serves as a supporting cell by surrounding and isolating the other cell types from each other; secrete a dense amorphous material that surrounds the microvilli in the taste pore. This cell type expresses a glial glutumate transporter, GLAST.")
AnnotationAssertion(terms:contributor obo:CL_0002289 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002289 "2010-09-13T10:57:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002289 "FMA:62356")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002289 "dark tongue cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002289 "type I taste cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002289 "type taste 1 cell")
AnnotationAssertion(rdfs:label obo:CL_0002289 "type I taste bud cell")
SubClassOf(obo:CL_0002289 obo:CL_0000209)
SubClassOf(obo:CL_0002289 obo:CL_0000703)

# Class: obo:CL_0002290 (Y chromosome-bearing sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721669743") obo:IAO_0000115 obo:CL_0002290 "A sperm bearing a Y chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum.")
AnnotationAssertion(terms:contributor obo:CL_0002290 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002290 "2010-09-13T11:35:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002290 "FMA:84058")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002290 "Y bearing sperm")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002290 "Y-bearing sperm")
AnnotationAssertion(rdfs:label obo:CL_0002290 "Y chromosome-bearing sperm cell")
SubClassOf(obo:CL_0002290 obo:CL_0000019)

# Class: obo:CL_0002291 (X chromosome-bearing sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721669743") obo:IAO_0000115 obo:CL_0002291 "A sperm bearing an X chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum.")
AnnotationAssertion(terms:contributor obo:CL_0002291 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002291 "2010-09-13T11:35:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002291 "FMA:84057")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002291 "X bearing sperm")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002291 "X-bearing sperm")
AnnotationAssertion(rdfs:label obo:CL_0002291 "X chromosome-bearing sperm cell")
SubClassOf(obo:CL_0002291 obo:CL_0000019)

# Class: obo:CL_0002292 (type I cell of carotid body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002292 "A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters.")
AnnotationAssertion(terms:contributor obo:CL_0002292 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002292 "2010-09-13T01:40:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002292 "FMA:84186")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002292 "glomus cell")
AnnotationAssertion(rdfs:label obo:CL_0002292 "type I cell of carotid body")
SubClassOf(obo:CL_0002292 obo:CL_0000710)

# Class: obo:CL_0002293 (epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:72208") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002293 "An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies.")
AnnotationAssertion(terms:contributor obo:CL_0002293 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002293 "2010-09-13T02:34:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002293 "CALOHA:TS-1040")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002293 "FMA:72208")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002293 "epithelial cell of thymus gland")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002293 "epithelial reticular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002293 "epithelial reticular cell of thymus")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002293 "thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002293 "epithelial cell of thymus")
EquivalentClasses(obo:CL_0002293 ObjectIntersectionOf(obo:CL_0002076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002293 obo:CL_0002076)

# Class: obo:CL_0002294 (type-1 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002294 "An epithelial cell with a well defined Golgi apparatus that makes up the continuous layer of cells bordering the thymic tissue beneath the capsule.")
AnnotationAssertion(terms:contributor obo:CL_0002294 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002294 "2010-09-13T02:37:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002294 "FMA:72209")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18194204") Annotation(oboInOwl:hasDbXref "PMID:2694455") oboInOwl:hasRelatedSynonym obo:CL_0002294 "subcapsular thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002294 "type-1 epithelial cell of thymus")
SubClassOf(obo:CL_0002294 obo:CL_0002364)

# Class: obo:CL_0002295 (type-6 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19721455") Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002295 "A thymic epithelial cell that has an eccentric, round, or irregularly shaped hetero or euchromatic nucleus. The hallmark of this cell type is the presence of vacuoles, which are clustered in one area of the cytoplasm in the vicinity of the nucleus. The vacuoles are small and acquire a grape-like form, occasionally showing delicate internal microvillous projections.")
AnnotationAssertion(terms:contributor obo:CL_0002295 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002295 "2010-09-13T02:37:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002295 "FMA:72214")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002295 "cystic thymic epithelial cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002295 "large mTEC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002295 "large medullary thymic epithelial cells")
AnnotationAssertion(rdfs:label obo:CL_0002295 "type-6 epithelial cell of thymus")
SubClassOf(obo:CL_0002295 obo:CL_0002365)

# Class: obo:CL_0002296 (type-4 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0412046911") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002296 "An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus.")
AnnotationAssertion(terms:contributor obo:CL_0002296 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002296 "2010-09-13T02:37:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002296 "FMA:72212")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002296 "dark thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002296 "type-4 epithelial cell of thymus")
SubClassOf(obo:CL_0002296 obo:CL_0002364)
SubClassOf(obo:CL_0002296 obo:CL_0002365)

# Class: obo:CL_0002297 (type-3 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002297 "A thymic epithelial cell with moderate nuclear and cytoplasmic electron-density. Scattered in the cortex, this cell type is predominant in the mid and deep cortex.")
AnnotationAssertion(terms:contributor obo:CL_0002297 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002297 "2010-09-13T02:37:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002297 "FMA:72211")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002297 "intermediate thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002297 "type-3 epithelial cell of thymus")
SubClassOf(obo:CL_0002297 obo:CL_0002364)

# Class: obo:CL_0002298 (type-5 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "PMID:19721455") Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002298 "A thymic epithelial cell type with low nuclear and cytoplasmic electrondensity; has a round, euchromatic nucleus and occurs in small groups at the corticomedullary junction or scattered singly in the medulla.")
AnnotationAssertion(terms:contributor obo:CL_0002298 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002298 "2010-09-13T02:37:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002298 "FMA:72213")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002298 "undifferentiated mTEC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002298 "undifferentiated medullary thymic epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002298 "undifferentiated thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002298 "type-5 epithelial cell of thymus")
SubClassOf(obo:CL_0002298 obo:CL_0002365)

# Class: obo:CL_0002299 (type-2 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0412046911") Annotation(oboInOwl:hasDbXref "PMID:9264335") obo:IAO_0000115 obo:CL_0002299 "An epithelial cell scattered in the cortex, predominant in the outer cortex with a large pale nucleus and a prominent nucleolus.")
AnnotationAssertion(terms:contributor obo:CL_0002299 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002299 "2010-09-13T02:37:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002299 "FMA:72210")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002299 "pale thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002299 "type-2 epithelial cell of thymus")
SubClassOf(obo:CL_0002299 obo:CL_0002364)

# Class: obo:CL_0002300 (type-7 epithelial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19721455") obo:IAO_0000115 obo:CL_0002300 "A small medullary thymic epithelial cell with a spindle shape, often arranged in groups and connected to each other by large desmosomes and interdigitations. The cytoplasm is sparse, with scanty organelles and thick bundles of cytokeratin.")
AnnotationAssertion(terms:contributor obo:CL_0002300 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002300 "2010-09-13T03:23:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002300 "spindle shaped mTEC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002300 "spindle shaped medullary thymic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002300 "type-7 epithelial cell of thymus")
SubClassOf(obo:CL_0002300 obo:CL_0002365)

# Class: obo:CL_0002301 (type B synovial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") Annotation(oboInOwl:hasDbXref "PMID:34433485") Annotation(oboInOwl:hasDbXref "PMID:34772990") obo:IAO_0000115 obo:CL_0002301 "A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles.")
AnnotationAssertion(terms:contributor obo:CL_0002301 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:contributor obo:CL_0002301 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002301 "2010-09-13T03:39:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002301 "BTO:0003652")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002301 "FMA:66788")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002301 "fibroblast-like synoviocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23147896") oboInOwl:hasExactSynonym obo:CL_0002301 "synovial fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34433485") Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/Fibroblast-like_synoviocyte") rdfs:comment obo:CL_0002301 "Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis.")
AnnotationAssertion(rdfs:label obo:CL_0002301 "type B synovial cell")
EquivalentClasses(obo:CL_0002301 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002018)))
SubClassOf(obo:CL_0002301 obo:CL_0000214)
SubClassOf(obo:CL_0002301 obo:CL_0000499)
SubClassOf(obo:CL_0002301 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030213))
SubClassOf(obo:CL_0002301 ObjectSomeValuesFrom(obo:RO_0003000 obo:UBERON_0001090))

# Class: obo:CL_0002302 (type A synovial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002302 "A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum.")
AnnotationAssertion(terms:contributor obo:CL_0002302 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002302 "2010-09-13T03:39:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002302 "FMA:66787")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002302 "type A synoviocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10770586") rdfs:comment obo:CL_0002302 "Type A cells are usually round and located in the upper part of the synovial intima.")
AnnotationAssertion(rdfs:label obo:CL_0002302 "type A synovial cell")
SubClassOf(obo:CL_0002302 obo:CL_0000214)
SubClassOf(obo:CL_0002302 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002018))
SubClassOf(Annotation(oboInOwl:hasDbXref "PMID:10770586") obo:CL_0002302 ObjectSomeValuesFrom(obo:RO_0001000 obo:CL_0000842))
SubClassOf(obo:CL_0002302 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909))

# Class: obo:CL_0002303 (pigmented ciliary epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15106942") obo:IAO_0000115 obo:CL_0002303 "A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions.")
AnnotationAssertion(terms:contributor obo:CL_0002303 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002303 "2010-09-13T04:09:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002303 "FMA:70606")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.exer.2003.09.021") oboInOwl:hasExactSynonym obo:CL_0002303 "PE cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.exer.2003.09.021") rdfs:comment obo:CL_0002303 "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour.")
AnnotationAssertion(rdfs:label obo:CL_0002303 "pigmented ciliary epithelial cell")
SubClassOf(obo:CL_0002303 obo:CL_0000529)
SubClassOf(obo:CL_0002303 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001778))

# Class: obo:CL_0002304 (non-pigmented ciliary epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15106942") obo:IAO_0000115 obo:CL_0002304 "A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye.")
AnnotationAssertion(terms:contributor obo:CL_0002304 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002304 "2010-09-13T04:09:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002304 "FMA:70607")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.exer.2003.09.021") oboInOwl:hasExactSynonym obo:CL_0002304 "NPE cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10913011") oboInOwl:hasExactSynonym obo:CL_0002304 "nonpigmented ciliary epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.exer.2003.09.021") rdfs:comment obo:CL_0002304 "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour.")
AnnotationAssertion(rdfs:label obo:CL_0002304 "non-pigmented ciliary epithelial cell")
SubClassOf(obo:CL_0002304 obo:CL_0000710)
SubClassOf(obo:CL_0002304 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001778))

# Class: obo:CL_0002305 (epithelial cell of distal tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002305 "An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002305 "FMA:70981")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002305 "KUPO:0001055")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002305 "kidney distal tubule epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002305 "epithelial cell of distal tubule")
EquivalentClasses(obo:CL_0002305 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004135)))
SubClassOf(obo:CL_0002305 obo:CL_0002078)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002305 obo:CL_1000494)
SubClassOf(obo:CL_0002305 obo:CL_1000615)
SubClassOf(obo:CL_0002305 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004135))

# Class: obo:CL_0002306 (epithelial cell of proximal tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:1-4160-2328-3") obo:IAO_0000115 obo:CL_0002306 "An epithelial cell of the proximal tubule of the kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002306 "FMA:70973")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002306 "KUPO:0001044")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002306 "kidney proximal tubule epithelial cell")
AnnotationAssertion(rdfs:comment obo:CL_0002306 "The vast majority of proximal tubule epithelial cells have a brush border, but there are rare exceptions.")
AnnotationAssertion(rdfs:label obo:CL_0002306 "epithelial cell of proximal tubule")
EquivalentClasses(obo:CL_0002306 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004134)))
SubClassOf(obo:CL_0002306 obo:CL_0002078)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002306 obo:CL_1000494)
SubClassOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004134))

# Class: obo:CL_0002307 (brush border cell of the proximal tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:1-4160-2328-3") Annotation(oboInOwl:hasDbXref "PMID:23799132") obo:IAO_0000115 obo:CL_0002307 "A brush border epithelial cell located in the proximal tubule of the kidney, essential for reabsorbing substances like glucose and amino acids from the glomerular filtrate. These cells also secrete organic ions, playing a crucial role in maintaining kidney homeostasis, including electrolyte and acid-base balance, and excreting metabolic waste.")
AnnotationAssertion(terms:contributor obo:CL_0002307 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002307 "2010-09-14T11:29:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002307 "The vast majority of proximal tubule epithelial cells have a brush border, but there are rare exceptions.")
AnnotationAssertion(rdfs:label obo:CL_0002307 "brush border cell of the proximal tubule")
EquivalentClasses(obo:CL_0002307 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(obo:CL_0002307 obo:CL_0002306)

# Class: obo:CL_0002308 (epithelial cell of skin gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002308 "An epithelial cell of a skin gland.")
AnnotationAssertion(terms:contributor obo:CL_0002308 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002308 "2010-09-14T12:00:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002308 "FMA:70657")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002308 "epithelial cell of gland of skin")
AnnotationAssertion(rdfs:label obo:CL_0002308 "epithelial cell of skin gland")
EquivalentClasses(obo:CL_0002308 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002419)))
SubClassOf(obo:CL_0002308 obo:CL_0002159)

# Class: obo:CL_0002309 (corticotroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0517223651") obo:IAO_0000115 obo:CL_0002309 "A basophil chromphil cell of the anterior pitiutary gland that produce adrenocorticotropic hormone, melanocyte-stimulating hormone and lipotropin. This cell type is irregular in shape and has short dendritic processes which are inserted among other neighboring cells;")
AnnotationAssertion(terms:contributor obo:CL_0002309 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002309 "2010-09-14T02:08:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002309 "BTO:0002509")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002309 "FMA:83098")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002309 "MESH:D052680")
AnnotationAssertion(rdfs:label obo:CL_0002309 "corticotroph")
SubClassOf(obo:CL_0002309 obo:CL_0000467)
SubClassOf(obo:CL_0002309 obo:CL_0000639)

# Class: obo:CL_0002310 (mammosomatotroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002310 "An acidophil cell of the anterior pituitary gland that produces both prolactin and growth hormone.")
AnnotationAssertion(terms:contributor obo:CL_0002310 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002310 "2010-09-14T02:25:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002310 "FMA:83097")
AnnotationAssertion(rdfs:label obo:CL_0002310 "mammosomatotroph")
SubClassOf(obo:CL_0002310 obo:CL_0000295)
SubClassOf(obo:CL_0002310 obo:CL_0000439)
SubClassOf(obo:CL_0002310 obo:CL_0000638)

# Class: obo:CL_0002311 (mammotroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0002311 "An acidophilic cell of the anterior pituitary that produces prolactin.")
AnnotationAssertion(terms:contributor obo:CL_0002311 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002311 "2010-09-14T02:30:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002311 "FMA:83096")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "epsilon-acidophil")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "lactotrope")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "lactotroph")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "lactotropic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "mammotrope")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "mammotrophic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002311 "mammotropic cell")
AnnotationAssertion(rdfs:label obo:CL_0002311 "mammotroph")
SubClassOf(obo:CL_0002311 obo:CL_0000439)
SubClassOf(obo:CL_0002311 obo:CL_0000638)

# Class: obo:CL_0002312 (somatotroph)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SANBI:mhl") obo:IAO_0000115 obo:CL_0002312 "An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.")
AnnotationAssertion(terms:contributor obo:CL_0002312 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002312 "2010-09-14T02:33:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002312 "FMA:83095")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002312 "MESH:D052683")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002312 "somatotrope")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002312 "somatotropic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002312 "somatrophic cell")
AnnotationAssertion(rdfs:label obo:CL_0002312 "somatotroph")
SubClassOf(obo:CL_0002312 obo:CL_0000295)
SubClassOf(obo:CL_0002312 obo:CL_0000638)

# Class: obo:CL_0002313 (endocrine-paracrine cell of prostate gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002313 "An ecto-epithelial cell of the prostate gland that secretes hormones.")
AnnotationAssertion(terms:contributor obo:CL_0002313 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002313 "2010-09-14T03:01:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002313 "CALOHA:TS-1280")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002313 "FMA:74390")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002313 "FMA:86774")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002313 "glandular cell of prostate")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002313 "neuro-epithelial cell of prostate gland")
AnnotationAssertion(rdfs:label obo:CL_0002313 "endocrine-paracrine cell of prostate gland")
EquivalentClasses(obo:CL_0002313 ObjectIntersectionOf(obo:CL_0002159 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046879)))
SubClassOf(obo:CL_0002313 obo:CL_0000150)

# Class: obo:CL_0002314 (external supporting cell of vestibular epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20837532") obo:IAO_0000115 obo:CL_0002314 "An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein.")
AnnotationAssertion(terms:contributor obo:CL_0002314 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002314 "2010-09-14T03:20:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002314 "FMA:75809")
AnnotationAssertion(rdfs:label obo:CL_0002314 "external supporting cell of vestibular epithelium")
SubClassOf(obo:CL_0002314 obo:CL_0002316)

# Class: obo:CL_0002315 (supporting cell of cochlea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002315 "An epithelial supporting cell located in the cochlea.")
AnnotationAssertion(terms:contributor obo:CL_0002315 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002315 "2010-09-14T03:31:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002315 "FMA:79796")
AnnotationAssertion(rdfs:label obo:CL_0002315 "supporting cell of cochlea")
EquivalentClasses(obo:CL_0002315 ObjectIntersectionOf(obo:CL_0005014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001844)))

# Class: obo:CL_0002316 (supporting cell of vestibular epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20837532") obo:IAO_0000115 obo:CL_0002316 "A supporting cell of the vestibular epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002316 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002316 "2010-09-14T03:31:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002316 "FMA:75607")
AnnotationAssertion(rdfs:label obo:CL_0002316 "supporting cell of vestibular epithelium")
EquivalentClasses(obo:CL_0002316 ObjectIntersectionOf(obo:CL_0005014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001862)))

# Class: obo:CL_0002317 (external limiting cell of vestibular epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002317 "An external limiting cell found in the vestibular epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002317 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002317 "2010-09-14T03:33:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002317 "FMA:75808")
AnnotationAssertion(rdfs:label obo:CL_0002317 "external limiting cell of vestibular epithelium")
SubClassOf(obo:CL_0002317 obo:CL_0002316)

# Class: obo:CL_0002318 (peripheral blood mesothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:14592528") obo:IAO_0000115 obo:CL_0002318 "A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium.")
AnnotationAssertion(terms:contributor obo:CL_0002318 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002318 "2010-09-15T10:47:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002318 "FMA:86712")
AnnotationAssertion(rdfs:label obo:CL_0002318 "peripheral blood mesothelial cell")
SubClassOf(obo:CL_0002318 obo:CL_0000081)
SubClassOf(obo:CL_0002318 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000077))

# Class: obo:CL_0002319 (neural cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") obo:IAO_0000115 obo:CL_0002319 "A cell that is part of the nervous system.")
AnnotationAssertion(terms:contributor obo:CL_0002319 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002319 "2010-09-15T01:34:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002319 "CALOHA:TS-2040")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002319 "FMA:70333")
AnnotationAssertion(rdfs:label obo:CL_0002319 "neural cell")
EquivalentClasses(obo:CL_0002319 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001016)))

# Class: obo:CL_0002320 (connective tissue cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0618947256") Annotation(oboInOwl:hasDbXref "PMID:19198652") Annotation(oboInOwl:hasDbXref "PMID:26043871") Annotation(oboInOwl:hasDbXref "PMID:31194383") obo:IAO_0000115 obo:CL_0002320 "A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest.")
AnnotationAssertion(terms:contributor obo:CL_0002320 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002320 "2010-09-15T03:01:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002320 "CALOHA:TS-2096")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002320 "FMA:63875")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002320 "MESH:D003239")
AnnotationAssertion(rdfs:label obo:CL_0002320 "connective tissue cell")
EquivalentClasses(obo:CL_0002320 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002384)))

# Class: obo:CL_0002321 (embryonic cell (metazoa))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:0618947256") obo:IAO_0000115 obo:CL_0002321 "A cell of the embryo.")
AnnotationAssertion(terms:contributor obo:CL_0002321 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002321 "2010-09-15T03:39:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002321 "CALOHA:TS-0263")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002321 "FMA:82840")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002321 "WBbt:0007028")
AnnotationAssertion(rdfs:label obo:CL_0002321 "embryonic cell (metazoa)")
SubClassOf(obo:CL_0002321 obo:CL_0000000)

# Class: obo:CL_0002322 (embryonic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:068340007X") Annotation(oboInOwl:hasDbXref "PMID:18179856") obo:IAO_0000115 obo:CL_0002322 "A stem cell of embryonic origin.")
AnnotationAssertion(terms:contributor obo:CL_0002322 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002322 "2010-09-15T03:44:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002322 "BTO:0001086")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002322 "CALOHA:TS-0263")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002322 "FMA:82841")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002322 "MESH:D053595")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002322 "ESC")
AnnotationAssertion(rdfs:comment obo:CL_0002322 "This is an in vitro cell type and may be removed in future releases. These cells are reportedly SSEA-4-positive, CD73-negative, and CD324-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002322 "embryonic stem cell")
SubClassOf(obo:CL_0002322 obo:CL_0000034)
SubClassOf(obo:CL_0002322 obo:CL_0002321)

# Class: obo:CL_0002323 (amniocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BFO:0000066") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:3211847") obo:IAO_0000115 obo:CL_0002323 "A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface.")
AnnotationAssertion(terms:contributor obo:CL_0002323 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002323 "2010-09-20T10:13:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002323 "BTO:0000066")
AnnotationAssertion(rdfs:label obo:CL_0002323 "amniocyte")
EquivalentClasses(obo:CL_0002323 ObjectIntersectionOf(obo:CL_0000349 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0000173)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002323 obo:CL_0000349)

# Class: obo:CL_0002324 (basal-myoepithelial cell of mammary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11250738") Annotation(oboInOwl:hasDbXref "PMID:19022771") Annotation(oboInOwl:hasDbXref "PMID:38059556") obo:IAO_0000115 obo:CL_0002324 "A myoepithelial cell that is part of a mammary gland and is located in the basal layer. During lactation, a basal-myoepithelial cell of mammary gland contracts under the stimulation of oxytocin. In humans, a basal-myoepithelial cell of mammary gland can be identified by high levels of CD49f and low levels of EpCAM.")
AnnotationAssertion(terms:contributor obo:CL_0002324 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_0002324 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(terms:contributor obo:CL_0002324 <https://orcid.org/0000-0003-4969-670X>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002324 "2010-09-20T11:42:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37694522") oboInOwl:hasBroadSynonym obo:CL_0002324 "basal myoepithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") oboInOwl:hasBroadSynonym obo:CL_0002324 "basal-myoepithelial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002324 "CALOHA:TS-2378")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002324 "FMA:67800")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11250738") oboInOwl:hasExactSynonym obo:CL_0002324 "myoepithelial cell of mammary gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67800") oboInOwl:hasNarrowSynonym obo:CL_0002324 "basal cell of lactiferous duct")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0002324 "myoepithelial cell of lactiferous gland")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002324 "B-Myo cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38059556") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002324 "BM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002324 "basal")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38059556") rdfs:comment obo:CL_0002324 "Due inconsistencies in naming this and other mammary gland epithelial cell types, several mammary gland experts gathered for a breast atlas annotation jamboree organized by Chan-Zuckerberg initiative. They agreed to label this cell type as basal-myoepithelial cell (and abbreviated: B-Myo cell).")
AnnotationAssertion(rdfs:label obo:CL_0002324 "basal-myoepithelial cell of mammary gland")
EquivalentClasses(obo:CL_0002324 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911)))
SubClassOf(obo:CL_0002324 obo:CL_0000185)

# Class: obo:CL_0002325 (lactocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022771") Annotation(oboInOwl:hasDbXref "PMID:28717367") Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasDbXref "PMID:35377806") Annotation(oboInOwl:hasDbXref "doi:10.1177/156482659601700404") obo:IAO_0000115 obo:CL_0002325 "A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland.")
AnnotationAssertion(terms:contributor obo:CL_0002325 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_0002325 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(terms:contributor obo:CL_0002325 <https://orcid.org/0000-0003-4361-817X>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002325 "2010-09-20T01:30:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19022771") oboInOwl:hasBroadSynonym obo:CL_0002325 "mammary alveolar cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002325 "FMA:74506")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002325 "FMA:79866")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002325 "epithelial cell of lactiferous gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") oboInOwl:hasExactSynonym obo:CL_0002325 "lactaction-associated mammary epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") oboInOwl:hasExactSynonym obo:CL_0002325 "lactation-derived mammary cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002325 "luminal cell of alveolus of lactiferous gland")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002325 "mammary alveolar epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002325 "mammary gland alveolar epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002325 "LMC")
AnnotationAssertion(rdfs:label obo:CL_0002325 "lactocyte")
EquivalentClasses(obo:CL_0002325 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003214)))
SubClassOf(obo:CL_0002325 obo:CL_0000314)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002325 obo:CL_0002159)
SubClassOf(obo:CL_0002325 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4033057))

# Class: obo:CL_0002326 (luminal epithelial cell of mammary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022771") obo:IAO_0000115 obo:CL_0002326 "A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast.")
AnnotationAssertion(terms:contributor obo:CL_0002326 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002326 "2010-09-20T01:37:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21930782") oboInOwl:hasBroadSynonym obo:CL_0002326 "mature luminal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002326 "FMA:73280")
AnnotationAssertion(rdfs:label obo:CL_0002326 "luminal epithelial cell of mammary gland")
SubClassOf(obo:CL_0002326 obo:CL_0000069)
SubClassOf(obo:CL_0002326 obo:CL_0002327)
SubClassOf(obo:CL_0002326 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0009116))

# Class: obo:CL_0002327 (mammary gland epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022771") obo:IAO_0000115 obo:CL_0002327 "An epithelial cell of the mammary gland.")
AnnotationAssertion(terms:contributor obo:CL_0002327 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002327 "2010-09-20T01:49:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002327 "BTO:0004300")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002327 "breast epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002327 "mammary epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002327 "mammary gland epithelial cell")
EquivalentClasses(obo:CL_0002327 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911)))

# Class: obo:CL_0002328 (bronchial epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002328 "An epithelial cell of the bronchus.")
AnnotationAssertion(terms:contributor obo:CL_0002328 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002328 "2010-09-20T02:00:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002328 "BTO:0002922")
AnnotationAssertion(rdfs:label obo:CL_0002328 "bronchial epithelial cell")
EquivalentClasses(obo:CL_0002328 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002185)))
SubClassOf(obo:CL_0002328 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031))

# Class: obo:CL_0002329 (basal epithelial cell of tracheobronchial tree)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002329 "An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury.")
AnnotationAssertion(terms:contributor obo:CL_0002329 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002329 "2010-09-20T02:10:36Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002329 "basal epithelial cell of tracheobronchial tree")
SubClassOf(obo:CL_0002329 obo:CL_0002202)

# Class: obo:CL_0002330 (undifferentiated cell of bronchus epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18757316") obo:IAO_0000115 obo:CL_0002330 "An undifferentiated columnar cell of the bronchus epithelium")
AnnotationAssertion(terms:contributor obo:CL_0002330 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002330 "2010-09-20T02:17:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002330 "undifferentiated cell of bronchus epithelium")
SubClassOf(obo:CL_0002330 obo:CL_0002328)

# Class: obo:CL_0002331 (obo:CL_0002331)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002331 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002331 obo:CL_1000349)
AnnotationAssertion(owl:deprecated obo:CL_0002331 "true"^^xsd:boolean)

# Class: obo:CL_0002332 (multiciliated epithelial cell of the bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18757316") obo:IAO_0000115 obo:CL_0002332 "A multi-ciliated epithelial cell located in the bronchus epithelium, characterized by a columnar shape and motile cilia on its apical surface.")
AnnotationAssertion(terms:contributor obo:CL_0002332 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002332 "2010-09-20T02:21:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002332 "ciliated epithelial cell of the bronchus")
AnnotationAssertion(rdfs:label obo:CL_0002332 "multiciliated epithelial cell of the bronchus")
EquivalentClasses(obo:CL_0002332 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_0002333 (neural crest derived adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17507398") obo:IAO_0000115 obo:CL_0002333 "An adipocyte derived from a neural crest cell.")
AnnotationAssertion(terms:contributor obo:CL_0002333 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002333 "2010-09-20T02:25:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002333 "neural crest derived adipocyte")
EquivalentClasses(obo:CL_0002333 ObjectIntersectionOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)))
SubClassOf(obo:CL_0002333 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000005))

# Class: obo:CL_0002334 (preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18793119") obo:IAO_0000115 obo:CL_0002334 "An undifferentiated fibroblast that can be stimulated to form a fat cell.")
AnnotationAssertion(terms:contributor obo:CL_0002334 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002334 "2010-09-20T02:31:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002334 "BTO:0001107")
AnnotationAssertion(rdfs:label obo:CL_0002334 "preadipocyte")
SubClassOf(obo:CL_0002334 obo:CL_0000057)

# Class: obo:CL_0002335 (brown preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18719589") obo:IAO_0000115 obo:CL_0002335 "A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha).")
AnnotationAssertion(terms:contributor obo:CL_0002335 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002335 "2010-09-20T02:38:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002335 "brown preadipocyte")
SubClassOf(obo:CL_0002335 obo:CL_0002334)

# Class: obo:CL_0002336 (buccal mucosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MESH:D009061") obo:IAO_0000115 obo:CL_0002336 "An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek.")
AnnotationAssertion(terms:contributor obo:CL_0002336 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002336 "2010-09-20T02:52:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002336 "buccal mucosa cell")
SubClassOf(obo:CL_0002336 obo:CL_0002261)

# Class: obo:CL_0002337 (keratinocyte stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15339667") Annotation(oboInOwl:hasDbXref "PMID:20568222") Annotation(oboInOwl:hasDbXref "PMID:9520465") obo:IAO_0000115 obo:CL_0002337 "A stem cell found in the basal layer of the epidermis, hair follicle, and sebaceous gland, characterised by its quiescent nature, high proliferative potential, and capacity for long-term self-renewal. This cell maintains epidermal homeostasis by producing transit-amplifying cells that differentiate to replenish the stratified squamous epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002337 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002337 "2010-09-20T03:07:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9520465") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002337 "KSC")
AnnotationAssertion(rdfs:label obo:CL_0002337 "keratinocyte stem cell")
SubClassOf(obo:CL_0002337 obo:CL_0000048)
SubClassOf(obo:CL_0002337 obo:CL_0000312)
SubClassOf(obo:CL_0002337 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036334))

# Class: obo:CL_0002338 (CD56-positive, CD161-positive immature natural killer cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:12457618") obo:IAO_0000115 obo:CL_0002338 "A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002338 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002338 "2010-09-21T10:06:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12457618") oboInOwl:hasRelatedSynonym obo:CL_0002338 "p-NK")
AnnotationAssertion(rdfs:comment obo:CL_0002338 "Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily).")
AnnotationAssertion(rdfs:label obo:CL_0002338 "CD56-positive, CD161-positive immature natural killer cell, human")
EquivalentClasses(obo:CL_0002338 ObjectIntersectionOf(obo:CL_0000823 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001024) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001381) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_0002338 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002344))

# Class: obo:CL_0002339 (prostate stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15226377") obo:IAO_0000115 obo:CL_0002339 "A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002339 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002339 "2010-09-20T03:21:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002339 "CD133-positive prostate epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002339 "prostate stem cell")
EquivalentClasses(obo:CL_0002339 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367)))
SubClassOf(obo:CL_0002339 obo:CL_0000048)
SubClassOf(obo:CL_0002339 obo:CL_0002341)

# Class: obo:CL_0002340 (luminal cell of prostate epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002340 "The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival.")
AnnotationAssertion(terms:contributor obo:CL_0002340 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002340 "2010-09-20T03:34:05Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002340 "luminal cell of prostate epithelium")
SubClassOf(obo:CL_0002340 obo:CL_0002231)

# Class: obo:CL_0002341 (basal cell of prostate epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC2673349") obo:IAO_0000115 obo:CL_0002341 "An undifferentiated cell of the prostate epithelium that lacks secretory activity.")
AnnotationAssertion(terms:contributor obo:CL_0002341 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002341 "2010-09-20T03:34:10Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002341 "basal cell of prostate epithelium")
SubClassOf(obo:CL_0002341 obo:CL_0002231)

# Class: obo:CL_0002342 (circulating endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19652886") obo:IAO_0000115 obo:CL_0002342 "A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage.")
AnnotationAssertion(terms:contributor obo:CL_0002342 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002342 "2010-09-20T03:49:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002342 "circulating endothelial cell")
SubClassOf(obo:CL_0002342 obo:CL_0000115)

# Class: obo:CL_0002343 (decidual natural killer cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14568979") Annotation(oboInOwl:hasDbXref "PMID:19800965") obo:IAO_0000115 obo:CL_0002343 "A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy.")
AnnotationAssertion(terms:contributor obo:CL_0002343 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002343 "2010-09-20T04:00:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002343 "dNK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002343 "decidual NK cell")
AnnotationAssertion(rdfs:label obo:CL_0002343 "decidual natural killer cell, human")
EquivalentClasses(obo:CL_0002343 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009766) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001024)))
SubClassOf(obo:CL_0002343 obo:CL_4052028)
SubClassOf(obo:CL_0002343 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002450))

# Class: obo:CL_0002344 (CD56-negative, CD161-positive immature natural killer cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") Annotation(oboInOwl:hasDbXref "PMID:12457618") obo:IAO_0000115 obo:CL_0002344 "A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002344 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002344 "2010-09-20T04:33:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12457618") oboInOwl:hasRelatedSynonym obo:CL_0002344 "p-NK")
AnnotationAssertion(rdfs:comment obo:CL_0002344 "Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily).")
AnnotationAssertion(rdfs:label obo:CL_0002344 "CD56-negative, CD161-positive immature natural killer cell, human")
EquivalentClasses(obo:CL_0002344 ObjectIntersectionOf(obo:CL_0000823 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001381) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0002345 (CD27-low, CD11b-low immature natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19949422") Annotation(oboInOwl:hasDbXref "http:www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002345 "An immature natural killer cell that is NK1.1-positive, DX5-positive, Ly49-positive, CD27-low and CD11b-low. This cell type is found in high numbers in the liver.")
AnnotationAssertion(terms:contributor obo:CL_0002345 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002345 "2010-09-20T04:41:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002345 "preNK.BM")
AnnotationAssertion(rdfs:comment obo:CL_0002345 "Markers are associated with mouse cells.")
AnnotationAssertion(rdfs:label obo:CL_0002345 "CD27-low, CD11b-low immature natural killer cell, mouse")
EquivalentClasses(obo:CL_0002345 ObjectIntersectionOf(obo:CL_0000823 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001008) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002977) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009616) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001963)))
SubClassOf(obo:CL_0002345 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002346))

# Class: obo:CL_0002346 (Dx5-negative, NK1.1-positive immature natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12766763") obo:IAO_0000115 obo:CL_0002346 "An immature natural killer cell that is NK1.1-positive and DX-5 negative.")
AnnotationAssertion(terms:contributor obo:CL_0002346 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002346 "2010-09-21T10:11:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002346 "Dx5-negative, NK1.1-positive immature natural killer cell, mouse")
EquivalentClasses(obo:CL_0002346 ObjectIntersectionOf(obo:CL_0000823 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001008) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002977) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002347 (CD27-high, CD11b-high natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19949422") obo:IAO_0000115 obo:CL_0002347 "A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion.")
AnnotationAssertion(terms:contributor obo:CL_0002347 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002347 "2010-09-21T10:19:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002347 "CD27-high, CD11b-high natural killer cell, mouse")
EquivalentClasses(obo:CL_0002347 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001963)))
SubClassOf(obo:CL_0002347 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002349))

# Class: obo:CL_0002348 (CD27-low, CD11b-high natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1994922") obo:IAO_0000115 obo:CL_0002348 "A CD27-low, CD11b-high natural killer cell that has a higher threshold of activation due to higher expression of inhibitory receptors.")
AnnotationAssertion(terms:contributor obo:CL_0002348 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002348 "2010-09-21T10:19:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002348 "CD27-low, CD11b-high natural killer cell, mouse")
EquivalentClasses(obo:CL_0002348 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001963)))
SubClassOf(obo:CL_0002348 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002347))

# Class: obo:CL_0002349 (CD27-high, CD11b-low natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:1994922") obo:IAO_0000115 obo:CL_0002349 "A natural killer cell that is CD27-high and CD11b-low.")
AnnotationAssertion(terms:contributor obo:CL_0002349 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002349 "2010-09-21T10:20:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002349 "CD27-high, CD11b-low natural killer cell, mouse")
EquivalentClasses(obo:CL_0002349 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(obo:CL_0002349 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002345))

# Class: obo:CL_0002350 (endocardial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISSN:0452-3458") obo:IAO_0000115 obo:CL_0002350 "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.")
AnnotationAssertion(terms:contributor obo:CL_0002350 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002350 "2010-09-21T04:33:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002350 "FMA:75621")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002350 "endocardial endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:75621") oboInOwl:hasExactSynonym obo:CL_0002350 "endothelial cell of endocardium")
AnnotationAssertion(rdfs:label obo:CL_0002350 "endocardial cell")
EquivalentClasses(obo:CL_0002350 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002165)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002350 obo:CL_0000115)

# Class: obo:CL_0002351 (progenitor cell of endocrine pancreas)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20025937") Annotation(oboInOwl:hasDbXref "PMID:20217494") Annotation(oboInOwl:hasDbXref "PMID:22728667") obo:IAO_0000115 obo:CL_0002351 "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.")
AnnotationAssertion(terms:contributor obo:CL_0002351 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002351 "2010-09-21T04:41:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002351 "pancreatic endocrine progenitor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002351 "pancreatic islet progenitor cell")
AnnotationAssertion(rdfs:label obo:CL_0002351 "progenitor cell of endocrine pancreas")
SubClassOf(obo:CL_0002351 obo:CL_0011026)

# Class: obo:CL_0002352 (gestational hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:978-60327-246-6") obo:IAO_0000115 obo:CL_0002352 "A hematopoietic stem cell that exists during embryogenesis.")
AnnotationAssertion(terms:contributor obo:CL_0002352 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002352 "2010-09-22T09:05:13Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002352 "gestational hematopoietic stem cell")
EquivalentClasses(obo:CL_0002352 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922)))
SubClassOf(obo:CL_0002352 obo:CL_0000037)

# Class: obo:CL_0002353 (fetal liver hematopoietic progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:978-1-60327-346-6") Annotation(oboInOwl:hasDbXref "PMID:16569764") obo:IAO_0000115 obo:CL_0002353 "A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002353 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002353 "2010-09-22T09:08:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002353 "fetal liver hematopoietic progenitor cell")
EquivalentClasses(obo:CL_0002353 ObjectIntersectionOf(obo:CL_0002352 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001308) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001896) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042611) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002353 obo:CL_0002352)
SubClassOf(obo:CL_0002353 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107))

# Class: obo:CL_0002354 (yolk sac hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "doi:10.1097/MOH.0b013e3282f97ae1") obo:IAO_0000115 obo:CL_0002354 "A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002354 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002354 "2010-09-22T09:08:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002354 "hemangioblast precursor")
AnnotationAssertion(rdfs:label obo:CL_0002354 "yolk sac hematopoietic stem cell")
EquivalentClasses(obo:CL_0002354 ObjectIntersectionOf(obo:CL_0002352 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042611) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001006) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002354 obo:CL_0002352)
SubClassOf(obo:CL_0002354 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001040))

# Class: obo:CL_0002355 (primitive red blood cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1097/MOH.0b013e3282f97ae1") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11495698") obo:IAO_0000115 obo:CL_0002355 "A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation.")
AnnotationAssertion(terms:contributor obo:CL_0002355 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002355 "2010-09-22T09:27:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002355 "primitive erythroblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002355 "primitive erythrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002355 "primitive erythroid cell")
AnnotationAssertion(rdfs:label obo:CL_0002355 "primitive red blood cell")
EquivalentClasses(obo:CL_0002355 ObjectIntersectionOf(obo:CL_0002417 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000008467) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000008857) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000586)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002355 obo:CL_0002417)
SubClassOf(obo:CL_0002355 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002361))

# Class: obo:CL_0002356 (primitive reticulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11495698") Annotation(oboInOwl:hasDbXref "doi:10.1097/MOH.0b013e3282f97ae1") obo:IAO_0000115 obo:CL_0002356 "A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains.")
AnnotationAssertion(terms:contributor obo:CL_0002356 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002356 "2010-09-22T09:35:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002356 "megalocyte")
AnnotationAssertion(rdfs:label obo:CL_0002356 "primitive reticulocyte")
EquivalentClasses(obo:CL_0002356 ObjectIntersectionOf(obo:CL_0002417 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000586) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002355)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002356 obo:CL_0002417)

# Class: obo:CL_0002357 (fetal derived definitive erythrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11495698") obo:IAO_0000115 obo:CL_0002357 "A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins.")
AnnotationAssertion(terms:contributor obo:CL_0002357 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002357 "2010-09-22T09:38:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002357 "macrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002357 "fetal derived definitive erythrocyte")
EquivalentClasses(obo:CL_0002357 ObjectIntersectionOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000008857)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002357 obo:CL_0000595)
SubClassOf(obo:CL_0002357 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002353))

# Class: obo:CL_0002358 (pyrenocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002358 "Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte.")
AnnotationAssertion(terms:contributor obo:CL_0002358 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002358 "2010-09-22T10:02:37Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002358 "pyrenocyte")
EquivalentClasses(obo:CL_0002358 ObjectIntersectionOf(obo:CL_0002417 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000587) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002355)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002358 obo:CL_0002417)

# Class: obo:CL_0002359 (placental hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:978-1-60327-346-6") obo:IAO_0000115 obo:CL_0002359 "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells.")
AnnotationAssertion(terms:contributor obo:CL_0002359 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002359 "2010-09-22T10:30:02Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002359 "placental hematopoietic stem cell")
EquivalentClasses(obo:CL_0002359 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))
SubClassOf(obo:CL_0002359 obo:CL_0002352)

# Class: obo:CL_0002360 (AGM hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:978-1-60327-346-6") obo:IAO_0000115 obo:CL_0002360 "A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC.")
AnnotationAssertion(terms:contributor obo:CL_0002360 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002360 "2010-09-22T10:31:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002360 "AGM hematopoietic stem cell")
SubClassOf(obo:CL_0002360 obo:CL_0002352)

# Class: obo:CL_0002361 (primitive erythroid progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0813817986") Annotation(oboInOwl:hasDbXref "PMID:20711979") obo:IAO_0000115 obo:CL_0002361 "A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41.")
AnnotationAssertion(terms:contributor obo:CL_0002361 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002361 "2010-09-22T10:47:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002361 "EryP-CFC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002361 "inner blood island hemangioblast")
AnnotationAssertion(rdfs:label obo:CL_0002361 "primitive erythroid progenitor")
EquivalentClasses(obo:CL_0002361 ObjectIntersectionOf(obo:CL_0002417 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002361 obo:CL_0002417)
SubClassOf(obo:CL_0002361 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002418))

# Class: obo:CL_0002362 (cerebellar granule cell precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:14745007") obo:IAO_0000115 obo:CL_0002362 "A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002362 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002362 "2010-09-22T01:40:44Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") oboInOwl:hasBroadSynonym obo:CL_0002362 "granule cell precursor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") oboInOwl:hasBroadSynonym obo:CL_0002362 "granule cell progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fncir.2020.611841") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002362 "GCP")
AnnotationAssertion(rdfs:label obo:CL_0002362 "cerebellar granule cell precursor")
SubClassOf(obo:CL_0002362 obo:CL_0000031)
SubClassOf(obo:CL_0002362 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009841))

# Class: obo:CL_0002363 (keratocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:9780702029585") obo:IAO_0000115 obo:CL_0002363 "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.")
AnnotationAssertion(terms:contributor obo:CL_0002363 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002363 "2010-09-22T01:57:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002363 "corneal fibroblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002363 "corneal keratocyte")
AnnotationAssertion(rdfs:label obo:CL_0002363 "keratocyte")
EquivalentClasses(obo:CL_0002363 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001777)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002363 obo:CL_0000057)
SubClassOf(obo:CL_0002363 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0002364 (cortical thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18403190") obo:IAO_0000115 obo:CL_0002364 "An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells.")
AnnotationAssertion(terms:contributor obo:CL_0002364 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002364 "2010-09-23T03:17:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002364 "BTO:0004562")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002364 "cTEC")
AnnotationAssertion(rdfs:label obo:CL_0002364 "cortical thymic epithelial cell")
EquivalentClasses(obo:CL_0002364 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002123)))
SubClassOf(obo:CL_0002364 obo:CL_0002293)

# Class: obo:CL_0002365 (medullary thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18180458") obo:IAO_0000115 obo:CL_0002365 "An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output.")
AnnotationAssertion(terms:contributor obo:CL_0002365 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002365 "2010-09-23T03:17:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002365 "BTO:0004563")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002365 "mTEC")
AnnotationAssertion(rdfs:label obo:CL_0002365 "medullary thymic epithelial cell")
EquivalentClasses(obo:CL_0002365 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124)))
SubClassOf(obo:CL_0002365 obo:CL_0002293)

# Class: obo:CL_0002366 (myometrial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:11429640") obo:IAO_0000115 obo:CL_0002366 "A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin.")
AnnotationAssertion(terms:contributor obo:CL_0002366 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002366 "2010-09-23T03:46:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002366 "BTO:0004519")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002366 "myometrium smooth muscle cell")
AnnotationAssertion(rdfs:label obo:CL_0002366 "myometrial cell")
EquivalentClasses(obo:CL_0002366 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001296)))

# Class: obo:CL_0002367 (trabecular meshwork cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:14500801") Annotation(oboInOwl:hasDbXref "PMID:40136401") obo:IAO_0000115 obo:CL_0002367 "An ocular connective tissue cell that is part of the eye's trabecular meshwork and is directly responsible for regulating the outflow of aqueous humor from the anterior chamber of the eye, thereby maintaining proper intraocular pressure.")
AnnotationAssertion(terms:contributor obo:CL_0002367 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002367 "2010-09-23T04:18:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002367 "trabeculocyte")
AnnotationAssertion(rdfs:label obo:CL_0002367 "trabecular meshwork cell")
EquivalentClasses(obo:CL_0002367 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005969)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002367 obo:CL_0002320)

# Class: obo:CL_0002368 (respiratory tract epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002368 "An epithelial cell of the respiratory tract epithelium.  These cells have an endodermal origin.")
AnnotationAssertion(terms:contributor obo:CL_0002368 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002368 "2010-09-23T04:38:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002368 "BTO:0004533")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002368 "airway epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002368 "respiratory epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002368 "respiratory tract epithelial cell")
EquivalentClasses(obo:CL_0002368 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802)))
SubClassOf(obo:CL_0002368 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000223))

# Class: obo:CL_0002369 (fungal spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FAO:0000019") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002369 "A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions.")
AnnotationAssertion(terms:contributor obo:CL_0002369 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002369 "2010-10-01T09:02:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002369 "MESH:D013172")
AnnotationAssertion(rdfs:label obo:CL_0002369 "fungal spore")
SubClassOf(obo:CL_0002369 obo:CL_0000521)

# Class: obo:CL_0002370 (respiratory tract goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002370 "A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion.")
AnnotationAssertion(terms:contributor obo:CL_0002370 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002370 "2010-09-23T04:42:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002370 "respiratory goblet cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0010863") oboInOwl:hasExactSynonym obo:CL_0002370 "respiratory mucosa goblet cells")
AnnotationAssertion(rdfs:label obo:CL_0002370 "respiratory tract goblet cell")
EquivalentClasses(obo:CL_0002370 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802)))
SubClassOf(obo:CL_0002370 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802))

# Class: obo:CL_0002371 (obsolete somatic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002371 "OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0002371 <https://github.com/obophenotype/cell-ontology/issues/1150>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002371 obo:CL_0000000)
AnnotationAssertion(terms:contributor obo:CL_0002371 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002371 "2010-09-24T09:44:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002371 "BTO:0001268")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002371 "FMA:72300")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002371 "WBbt:0008378")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0002371 ubprop:_upper_level)
AnnotationAssertion(rdfs:label obo:CL_0002371 "obsolete somatic cell")
AnnotationAssertion(owl:deprecated obo:CL_0002371 "true"^^xsd:boolean)

# Class: obo:CL_0002372 (myotube)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") Annotation(oboInOwl:hasDbXref "PMID:22274696") obo:IAO_0000115 obo:CL_0002372 "A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development.")
AnnotationAssertion(terms:contributor obo:CL_0002372 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002372 "2010-09-24T01:13:01Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00005812") oboInOwl:hasExactSynonym obo:CL_0002372 "myofiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00005812") oboInOwl:hasExactSynonym obo:CL_0002372 "myofibril")
AnnotationAssertion(rdfs:label obo:CL_0002372 "myotube")
EquivalentClasses(obo:CL_0002372 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478)))
SubClassOf(obo:CL_0002372 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0000768))

# Class: obo:CL_0002373 (growth hormone releasing hormone secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dph") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002373 "A peptide hormone secreting cell that secretes growth hormone releasing hormone.")
AnnotationAssertion(terms:contributor obo:CL_0002373 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002373 "2010-09-24T01:36:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002373 "GHRH secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002373 "somatocrinin secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0002373 "growth hormone releasing hormone secreting cell")
SubClassOf(obo:CL_0002373 obo:CL_0000167)

# Class: obo:CL_0002374 (ear hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dph") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0192801023") obo:IAO_0000115 obo:CL_0002374 "A hair cell of the ear that contains the organs of balance and hearing.")
AnnotationAssertion(terms:contributor obo:CL_0002374 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002374 "2010-09-24T01:49:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002374 "ear receptor cell")
AnnotationAssertion(rdfs:label obo:CL_0002374 "ear hair cell")
EquivalentClasses(obo:CL_0002374 ObjectIntersectionOf(obo:CL_0000855 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001690)))

# Class: obo:CL_0002375 (Schwann cell precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15580626") Annotation(oboInOwl:hasDbXref "PMID:30971890") Annotation(oboInOwl:hasDbXref "PMID:35815410") obo:IAO_0000115 obo:CL_0002375 "A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage.")
AnnotationAssertion(terms:contributor obo:CL_0002375 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002375 "2010-09-24T02:06:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002375 "Schwann cell precursor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35815410") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002375 "SCP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35815410") rdfs:comment obo:CL_0002375 "Schwann cell precursor are capable of differentiating into Schwann cells and other cell types such as melanocytes, neurons, and mesenchymal cells.")
AnnotationAssertion(rdfs:label obo:CL_0002375 "Schwann cell precursor")
SubClassOf(obo:CL_0002375 obo:CL_0011026)
SubClassOf(obo:CL_0002375 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001402))
SubClassOf(obo:CL_0002375 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))
SubClassOf(obo:CL_0002375 ObjectSomeValuesFrom(obo:RO_0002387 obo:CL_0002573))

# Class: obo:CL_0002376 (non-myelinating Schwann cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002376 "A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells.")
AnnotationAssertion(terms:contributor obo:CL_0002376 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002376 "2010-09-24T02:10:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002376 "Schwann cell")
AnnotationAssertion(rdfs:label obo:CL_0002376 "non-myelinating Schwann cell")
SubClassOf(obo:CL_0002376 obo:CL_0002573)
SubClassOf(obo:CL_0002376 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002377))

# Class: obo:CL_0002377 (immature Schwann cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0002377 "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons.")
AnnotationAssertion(terms:contributor obo:CL_0002377 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002377 "2010-09-24T02:10:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002377 "Schwann cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002377 "ZFA:0001725")
AnnotationAssertion(rdfs:label obo:CL_0002377 "immature Schwann cell")
SubClassOf(obo:CL_0002377 obo:CL_0002573)
SubClassOf(obo:CL_0002377 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002375))

# Class: obo:CL_0002378 (immature Vgamma2-positive fetal thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org") obo:IAO_0000115 obo:CL_0002378 "A double negative thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive and is found in the fetal thymus.")
AnnotationAssertion(terms:contributor obo:CL_0002378 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002378 "2010-10-07T02:21:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002378 "fetal Vgamma2+ thymocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002378 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002378 "immature Vgamma2-positive fetal thymocyte")
SubClassOf(obo:CL_0002378 obo:CL_0002404)

# Class: obo:CL_0002379 (meningothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.aippg.net/forum/viewtopic.php?t=62590") obo:IAO_0000115 obo:CL_0002379 "A neurecto-epithelial cell found in the arachnoid villi of dura mater. This cell type facilitates flow of cerebrospinal fluid into the blood.")
AnnotationAssertion(terms:contributor obo:CL_0002379 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002379 "2010-09-28T02:23:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002379 "FMA:86588")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002379 "arachnoid cap cell")
AnnotationAssertion(rdfs:label obo:CL_0002379 "meningothelial cell")
SubClassOf(obo:CL_0002379 obo:CL_0000710)

# Class: obo:CL_0002380 (oospore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0851988857") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002380 "An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere.")
AnnotationAssertion(terms:contributor obo:CL_0002380 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002380 "2010-10-01T09:22:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002380 "FAO:0000039")
AnnotationAssertion(rdfs:label obo:CL_0002380 "oospore")
SubClassOf(obo:CL_0002380 obo:CL_0000605)

# Class: obo:CL_0002381 (uninucleate conidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002381 "A conidium that has only one nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002381 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002381 "2010-10-01T09:26:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002381 "FAO:0000025")
AnnotationAssertion(rdfs:label obo:CL_0002381 "uninucleate conidium")
SubClassOf(obo:CL_0002381 obo:CL_0000599)

# Class: obo:CL_0002382 (multinucleate conidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002382 "A conidium that has more than one nucleus.")
AnnotationAssertion(terms:contributor obo:CL_0002382 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002382 "2010-10-01T09:31:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002382 "FAO:0000033")
AnnotationAssertion(rdfs:label obo:CL_0002382 "multinucleate conidium")
SubClassOf(obo:CL_0002382 obo:CL_0000599)

# Class: obo:CL_0002383 (conidium of conidiophore head)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9529886") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002383 "A uninucleate spore formed on specialized cells or projections, sterigma, of a conidiophore head.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002383 "FAO:0000033")
AnnotationAssertion(rdfs:label obo:CL_0002383 "conidium of conidiophore head")
SubClassOf(obo:CL_0002383 obo:CL_0002381)

# Class: obo:CL_0002384 (uninucleate macroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002384 "A macroconidium that has only one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002384 "FAO:0000029")
AnnotationAssertion(rdfs:label obo:CL_0002384 "uninucleate macroconidium")
SubClassOf(obo:CL_0002384 obo:CL_0000606)
SubClassOf(obo:CL_0002384 obo:CL_0002381)

# Class: obo:CL_0002385 (blastoconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:2524423") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002385 "An oblong or round asexual spore formed from conidial chains.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002385 "BTO:0000127")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002385 "FAO:0000042")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002385 "blastospore")
AnnotationAssertion(rdfs:label obo:CL_0002385 "blastoconidium")
SubClassOf(obo:CL_0002385 obo:CL_0000606)

# Class: obo:CL_0002386 (multinucleate macroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002386 "A macroconidium that has more than one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002386 "FAO:0000035")
AnnotationAssertion(rdfs:label obo:CL_0002386 "multinucleate macroconidium")
SubClassOf(obo:CL_0002386 obo:CL_0000606)
SubClassOf(obo:CL_0002386 obo:CL_0002382)

# Class: obo:CL_0002387 (arthroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:2524423") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002387 "Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002387 "FAO:0000041")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002387 "arthrospore")
AnnotationAssertion(rdfs:label obo:CL_0002387 "arthroconidium")
SubClassOf(obo:CL_0002387 obo:CL_0000606)

# Class: obo:CL_0002388 (multinucleate arthroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002388 "An arthroconidium that has more than one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002388 "FAO:0000037")
AnnotationAssertion(rdfs:label obo:CL_0002388 "multinucleate arthroconidium")
SubClassOf(obo:CL_0002388 obo:CL_0002386)
SubClassOf(obo:CL_0002388 obo:CL_0002387)

# Class: obo:CL_0002389 (uninucleate arthroconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002389 "An arthroconidium that has only one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002389 "FAO:0000031")
AnnotationAssertion(rdfs:label obo:CL_0002389 "uninucleate arthroconidium")
SubClassOf(obo:CL_0002389 obo:CL_0002384)
SubClassOf(obo:CL_0002389 obo:CL_0002387)

# Class: obo:CL_0002390 (uninucleate blastconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002390 "A blastoconidium that has only one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002390 "FAO:0000030")
AnnotationAssertion(rdfs:label obo:CL_0002390 "uninucleate blastconidium")
SubClassOf(obo:CL_0002390 obo:CL_0002384)
SubClassOf(obo:CL_0002390 obo:CL_0002385)

# Class: obo:CL_0002391 (multinucleate blastoconidium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "SGD:clt") obo:IAO_0000115 obo:CL_0002391 "A blastoconidium that has more than one nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002391 "FAO:0000036")
AnnotationAssertion(rdfs:label obo:CL_0002391 "multinucleate blastoconidium")
SubClassOf(obo:CL_0002391 obo:CL_0002385)
SubClassOf(obo:CL_0002391 obo:CL_0002386)

# Class: obo:CL_0002392 (obsolete plant spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PO:0025017") obo:IAO_0000115 obo:CL_0002392 "Obsolete. Use PO:0025017 from Plant Ontology instead. A plant cell that arises through meiosis and develops into a gametophyte.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002392 obo:PO_0025017)
AnnotationAssertion(rdfs:label obo:CL_0002392 "obsolete plant spore")
AnnotationAssertion(owl:deprecated obo:CL_0002392 "true"^^xsd:boolean)

# Class: obo:CL_0002393 (intermediate monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:20870168") obo:IAO_0000115 obo:CL_0002393 "A monocyte that has characteristics of both patrolling and inflammatory monocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002393 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002393 "2010-10-04T10:52:03Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002393 "intermediate monocyte")
EquivalentClasses(obo:CL_0002393 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0030224) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001199) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289)))
SubClassOf(obo:CL_0002393 obo:CL_0000576)
SubClassOf(obo:CL_0002393 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000860))

# Class: obo:CL_0002394 (CD141-positive myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC2882828") Annotation(oboInOwl:hasDbXref "PMCID:PMC2882837") Annotation(oboInOwl:hasDbXref "PMID:17332250") Annotation(oboInOwl:hasDbXref "PMID:20628149") obo:IAO_0000115 obo:CL_0002394 "A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta.")
AnnotationAssertion(terms:contributor obo:CL_0002394 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002394 "2010-10-04T02:38:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002394 "Markers are found in human cells. Normally they represent 3-5% of peripheral blood mDCs (human). These cells express high levels of CD283 (TLR3), are capable of producing IL-12p70 and IFN-beta upon stimulation, and inducing a TH1 response [PMCID:PMC2882828]. They are also Necl2-positive. May be human equivalent of murine CD8-alpha-positive DCs.")
AnnotationAssertion(rdfs:label obo:CL_0002394 "CD141-positive myeloid dendritic cell")
EquivalentClasses(obo:CL_0002394 ObjectIntersectionOf(obo:CL_0000782 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002105) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002827) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032606) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042590)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002394 obo:CL_0000782)

# Class: obo:CL_0002395 (Gr1-high classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:27098205") Annotation(oboInOwl:hasDbXref "PMID:8890901") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002395 "A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002395 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002395 "2010-10-04T11:26:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002395 "Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product.")
AnnotationAssertion(rdfs:label obo:CL_0002395 "Gr1-high classical monocyte")
EquivalentClasses(obo:CL_0002395 ObjectIntersectionOf(obo:CL_0000860 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001206) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002980)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002395 obo:CL_0000860)

# Class: obo:CL_0002396 (CD14-low, CD16-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20870168") obo:IAO_0000115 obo:CL_0002396 "A patrolling monocyte that is CD14-low and CD16-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002396 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002396 "2010-10-04T12:25:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002396 "non-classical monocyte, human")
AnnotationAssertion(rdfs:comment obo:CL_0002396 "Markers are associated with human monocytes.")
AnnotationAssertion(rdfs:label obo:CL_0002396 "CD14-low, CD16-positive monocyte")
EquivalentClasses(obo:CL_0002396 ObjectIntersectionOf(obo:CL_0000875 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001889)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002396 obo:CL_0000875)
SubClassOf(obo:CL_0002396 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002397))

# Class: obo:CL_0002397 (CD14-positive, CD16-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:21937707") Annotation(oboInOwl:hasDbXref "PMID:22343568") obo:IAO_0000115 obo:CL_0002397 "A CD14-positive monocyte that is also CD16-positive and CCR2-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002397 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002397 "2010-10-04T12:49:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343568") oboInOwl:hasExactSynonym obo:CL_0002397 "CD16+ monocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002397 "This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ monocyte'. Markers are associated with human cells. Note that this cell type encompasses both human intermediate monocytes (CD14+, CD16-low), and human non-classical monocytes (CD14-low, CD16+).")
AnnotationAssertion(rdfs:label obo:CL_0002397 "CD14-positive, CD16-positive monocyte")
EquivalentClasses(obo:CL_0002397 ObjectIntersectionOf(obo:CL_0001054 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001199) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483)))
SubClassOf(obo:CL_0002397 obo:CL_0001054)

# Class: obo:CL_0002398 (Gr1-positive, CD43-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20628149") Annotation(oboInOwl:hasDbXref "PMID:27098205") obo:IAO_0000115 obo:CL_0002398 "An intermediate monocyte that is Gr1-positive, CD43-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002398 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002398 "2010-10-04T12:49:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002398 "Gr1-positive, CD43-positive monocyte")
EquivalentClasses(obo:CL_0002398 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002980) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))
SubClassOf(obo:CL_0002398 obo:CL_0002393)
SubClassOf(obo:CL_0002398 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002395))

# Class: obo:CL_0002399 (CD1c-positive myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20204387") Annotation(oboInOwl:hasDbXref "PMID:20628149") obo:IAO_0000115 obo:CL_0002399 "A myeloid dendritic cell that is CD1c-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002399 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002399 "2010-10-04T02:39:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002399 "Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha.")
AnnotationAssertion(rdfs:label obo:CL_0002399 "CD1c-positive myeloid dendritic cell")
EquivalentClasses(obo:CL_0002399 ObjectIntersectionOf(obo:CL_0000782 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002027) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032637)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002399 obo:CL_0000782)

# Class: obo:CL_0002400 (fraction B/C precursor B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:37442242") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002400 "A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002400 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002400 "2010-10-05T10:11:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002400 "fraction B/C precursor B cell")
EquivalentClasses(obo:CL_0002400 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001002) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002400 obo:CL_0000817)

# Class: obo:CL_0002401 (mature dendritic epithelial T cell precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002401 "A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18.")
AnnotationAssertion(terms:contributor obo:CL_0002401 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002401 "2010-10-07T02:05:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002401 "mature DEC precursor")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002401 "mature DETC precursor")
AnnotationAssertion(rdfs:comment obo:CL_0002401 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002401 "mature dendritic epithelial T cell precursor")
SubClassOf(obo:CL_0002401 obo:CL_0002404)
SubClassOf(obo:CL_0002401 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002218))

# Class: obo:CL_0002402 (Peyer's patch B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002402 "A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002402 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002402 "2010-10-05T11:18:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002402 "Peyers patch B cell")
AnnotationAssertion(rdfs:label obo:CL_0002402 "Peyer's patch B cell")
EquivalentClasses(obo:CL_0002402 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001211) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002402 obo:CL_0000785)

# Class: obo:CL_0002403 (mature Vgamma2-positive fetal thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002403 "A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus.")
AnnotationAssertion(terms:contributor obo:CL_0002403 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002403 "2010-10-07T02:24:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002403 "fetal Vgamma2-positive")
AnnotationAssertion(rdfs:comment obo:CL_0002403 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002403 "mature Vgamma2-positive fetal thymocyte")
SubClassOf(obo:CL_0002403 obo:CL_0002404)
SubClassOf(obo:CL_0002403 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002378))

# Class: obo:CL_0002404 (fetal thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002404 "A thymocyte found in the fetal thymus.")
AnnotationAssertion(terms:contributor obo:CL_0002404 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002404 "2010-10-07T02:28:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002404 "fetal thymocyte")
SubClassOf(obo:CL_0002404 obo:CL_0000893)

# Class: obo:CL_0002405 (gamma-delta thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20725107") obo:IAO_0000115 obo:CL_0002405 "A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative).")
AnnotationAssertion(terms:contributor obo:CL_0002405 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002405 "2010-10-07T02:33:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002405 "gammadelta thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002405 "gd thymocyte")
AnnotationAssertion(rdfs:label obo:CL_0002405 "gamma-delta thymocyte")
EquivalentClasses(obo:CL_0002405 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042106)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002405 obo:CL_0000893)

# Class: obo:CL_0002406 (immature Vgamma2-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org") obo:IAO_0000115 obo:CL_0002406 "A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002406 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002406 "2010-10-07T02:53:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002406 "Vgamma2-positive thymocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002406 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002406 "immature Vgamma2-positive thymocyte")
SubClassOf(obo:CL_0002406 obo:CL_0002405)

# Class: obo:CL_0002407 (mature Vgamma2-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002407 "A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002407 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002407 "2010-10-07T02:53:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002407 "Vgamma2-positive")
AnnotationAssertion(rdfs:comment obo:CL_0002407 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002407 "mature Vgamma2-positive thymocyte")
SubClassOf(obo:CL_0002407 obo:CL_0002405)
SubClassOf(obo:CL_0002407 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002406))

# Class: obo:CL_0002408 (immature Vgamma2-negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org") obo:IAO_0000115 obo:CL_0002408 "A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain that does not contain a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002408 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002408 "2010-10-07T02:59:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002408 "Vgamma2-negative thymocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002408 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002408 "immature Vgamma2-negative thymocyte")
SubClassOf(obo:CL_0002408 obo:CL_0002405)

# Class: obo:CL_0002409 (mature Vgamma2-negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002409 "A thymocyte that has a T cell receptor consisting of a gamma chain that does not contain the Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002409 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002409 "2010-10-07T02:59:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002409 "Vgamma2-negative")
AnnotationAssertion(rdfs:comment obo:CL_0002409 "NOTE: currently variable immune gene segments are not represented in the OBO Foundry. Cross-product definitions were not made as a result. Also, there are three different nomenclatures for the variable gamma segments.")
AnnotationAssertion(rdfs:label obo:CL_0002409 "mature Vgamma2-negative thymocyte")
SubClassOf(obo:CL_0002409 obo:CL_0002405)
SubClassOf(obo:CL_0002409 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002408))

# Class: obo:CL_0002410 (pancreatic stellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mah") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17200706") obo:IAO_0000115 obo:CL_0002410 "A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast.")
AnnotationAssertion(terms:contributor obo:CL_0002410 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002410 "2010-11-10T09:40:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002410 "MESH:D058954")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002410 "PaSC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002410 "pancreas stellate cell")
AnnotationAssertion(rdfs:label obo:CL_0002410 "pancreatic stellate cell")
SubClassOf(obo:CL_0002410 obo:CL_0000057)
SubClassOf(obo:CL_0002410 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264))

# Class: obo:CL_0002411 (Vgamma1.1-positive, Vdelta6.3-negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:32979762") Annotation(oboInOwl:hasDbXref "PMID:35757696") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002411 "A gamma-delta receptor that expresses Vgamma1.1 but does not express Vdelta6.3 chains in the T-cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002411 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002411 "2010-10-07T03:07:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002411 "Vg1.1-positive, Vd6.3-negative T cell")
AnnotationAssertion(rdfs:label obo:CL_0002411 "Vgamma1.1-positive, Vdelta6.3-negative thymocyte")
SubClassOf(obo:CL_0002411 obo:CL_0002405)
SubClassOf(obo:CL_0002411 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0002412 (Vgamma1.1-positive, Vdelta6.3-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:32979762") Annotation(oboInOwl:hasDbXref "PMID:35757696") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002412 "A gamma-delta receptor that expresses Vgamma1.1-Vdelta6.3 chains in the T-cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002412 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002412 "2010-10-07T03:03:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002412 "Vg1.1+Vd6.3+ T cell")
AnnotationAssertion(rdfs:label obo:CL_0002412 "Vgamma1.1-positive, Vdelta6.3-positive thymocyte")
SubClassOf(obo:CL_0002412 obo:CL_0002405)
SubClassOf(obo:CL_0002412 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0002413 (mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org") obo:IAO_0000115 obo:CL_0002413 "A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002413 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002413 "2010-10-07T03:10:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002413 "mature Vg1.1-positive, Vd6.3-negative T cell")
AnnotationAssertion(rdfs:label obo:CL_0002413 "mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte")
SubClassOf(obo:CL_0002413 obo:CL_0002411)

# Class: obo:CL_0002414 (immature Vgamma1.1-positive, Vdelta6.3-negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002414 "A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002414 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002414 "2010-10-07T03:10:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002414 "immature Vg1.1-positive, Vd6.3-negative T cell")
AnnotationAssertion(rdfs:label obo:CL_0002414 "immature Vgamma1.1-positive, Vdelta6.3-negative thymocyte")
SubClassOf(obo:CL_0002414 obo:CL_0002411)

# Class: obo:CL_0002415 (immature Vgamma1.1-positive, Vdelta6.3-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002415 "A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002415 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002415 "2010-10-07T03:10:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002415 "immature Vg1.1+Vd6.3+ T cell")
AnnotationAssertion(rdfs:label obo:CL_0002415 "immature Vgamma1.1-positive, Vdelta6.3-positive thymocyte")
SubClassOf(obo:CL_0002415 obo:CL_0002412)

# Class: obo:CL_0002416 (mature Vgamma1.1-positive, Vdelta6.3-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002416 "A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002416 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002416 "2010-10-07T03:10:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002416 "mature Vg1.1+Vd6.3+ T cell")
AnnotationAssertion(rdfs:label obo:CL_0002416 "mature Vgamma1.1-positive, Vdelta6.3-positive thymocyte")
SubClassOf(obo:CL_0002416 obo:CL_0002412)

# Class: obo:CL_0002417 (primitive erythroid lineage cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002417 "An immature or mature cell of the first erythroid lineage to arise during embryonic development.")
AnnotationAssertion(terms:contributor obo:CL_0002417 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002417 "2010-10-12T11:22:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002417 "primitive erythroid lineage cell")
SubClassOf(obo:CL_0002417 obo:CL_0000764)

# Class: obo:CL_0002418 (hemangioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0813817986") Annotation(oboInOwl:hasDbXref "PMID:11495698") obo:IAO_0000115 obo:CL_0002418 "A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_0002418 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002418 "2010-10-12T12:21:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002418 "MESH:D055018")
AnnotationAssertion(rdfs:label obo:CL_0002418 "hemangioblast")
SubClassOf(obo:CL_0002418 obo:CL_0000222)
SubClassOf(obo:CL_0002418 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002354))

# Class: obo:CL_0002419 (mature T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002419 "A T cell that expresses a T cell receptor complex and has completed T cell selection.")
AnnotationAssertion(terms:contributor obo:CL_0002419 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002419 "2010-10-12T01:56:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002419 "CD3e-positive T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002419 "mature T-cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002419 "CD3epsilon T cell")
AnnotationAssertion(rdfs:label obo:CL_0002419 "mature T cell")
EquivalentClasses(obo:CL_0002419 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042101) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002419 obo:CL_0000084)
SubClassOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001701))

# Class: obo:CL_0002420 (immature T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002420 "A T cell that has not completed T cell selection.")
AnnotationAssertion(terms:contributor obo:CL_0002420 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002420 "2010-10-12T01:56:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002420 "BTO:0001372")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002420 "CALOHA:TS-1042")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002420 "immature T-cell")
AnnotationAssertion(rdfs:label obo:CL_0002420 "immature T cell")
EquivalentClasses(obo:CL_0002420 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002420 obo:CL_0000084)
SubClassOf(obo:CL_0002420 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501))

# Class: obo:CL_0002421 (nucleated reticulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18182572") Annotation(oboInOwl:hasDbXref "PMID:9011180") Annotation(oboInOwl:hasDbXref "PMID:9046052") obo:IAO_0000115 obo:CL_0002421 "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.")
AnnotationAssertion(terms:contributor obo:CL_0002421 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002421 "2010-10-15T09:24:05Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002421 "nucleated reticulocyte")
EquivalentClasses(obo:CL_0002421 ObjectIntersectionOf(obo:CL_0000558 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002421 obo:CL_0000558)

# Class: obo:CL_0002422 (enucleated reticulocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0-12203-052-4") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0002422 "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes.")
AnnotationAssertion(terms:contributor obo:CL_0002422 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002422 "2010-10-15T09:24:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002422 "CALOHA:TS-0864")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002422 "FMA:66785")
AnnotationAssertion(rdfs:label obo:CL_0002422 "enucleated reticulocyte")
EquivalentClasses(obo:CL_0002422 ObjectIntersectionOf(obo:CL_0000558 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005840) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002422 obo:CL_0000558)

# Class: obo:CL_0002423 (DN2a thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20595614") obo:IAO_0000115 obo:CL_0002423 "A DN2 thymocyte that is Kit-hi.")
AnnotationAssertion(terms:contributor obo:CL_0002423 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002423 "2010-10-21T10:12:05Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002423 "Observed in mice. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0002423 "DN2a thymocyte")
EquivalentClasses(obo:CL_0002423 ObjectIntersectionOf(obo:CL_0000806 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002423 obo:CL_0000806)

# Class: obo:CL_0002424 (DN2b thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20595614") obo:IAO_0000115 obo:CL_0002424 "A DN2 thymocyte that is Kit-low.")
AnnotationAssertion(terms:contributor obo:CL_0002424 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002424 "2010-10-21T10:12:08Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002424 "Observed in mice. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.")
AnnotationAssertion(rdfs:label obo:CL_0002424 "DN2b thymocyte")
EquivalentClasses(obo:CL_0002424 ObjectIntersectionOf(obo:CL_0000806 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002424 obo:CL_0000806)
SubClassOf(obo:CL_0002424 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002423))

# Class: obo:CL_0002425 (early T lineage precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16551251") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002425 "A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002425 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002425 "2010-10-21T01:16:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002425 "ETP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002425 "preT.ETP.Th")
AnnotationAssertion(rdfs:comment obo:CL_0002425 "ETPs are reportedly CD1a-negative, CD4-negative, CD7-positive, CD8a-negative, CD8b-negative, CD33-low, CD34-high, CD38-low, CD45RA-positive, and CD45RO-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002425 "early T lineage precursor")
EquivalentClasses(obo:CL_0002425 ObjectIntersectionOf(obo:CL_0000827 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002425 obo:CL_0000827)

# Class: obo:CL_0002426 (CD11b-positive, CD27-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002426 "A mature natural killer cell that is CD11b-positive and CD27-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002426 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002426 "2010-10-25T03:07:59Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002426 "A natural killer cell that is NK1.1-positive, CD11b-positive, and CD27-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002426 "CD11b-positive, CD27-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002426 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002427 (resting double-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002427 "A double-positive, alpha-beta thymocyte that is small and not proliferating.")
AnnotationAssertion(terms:contributor obo:CL_0002427 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002427 "2010-10-21T01:59:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002427 "T.DP.sm.Th")
AnnotationAssertion(rdfs:label obo:CL_0002427 "resting double-positive thymocyte")
EquivalentClasses(obo:CL_0002427 ObjectIntersectionOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000587)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002427 obo:CL_0000809)

# Class: obo:CL_0002428 (double-positive blast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002428 "A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating.")
AnnotationAssertion(terms:contributor obo:CL_0002428 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002428 "2010-10-21T01:59:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002428 "T.DPb.Th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002428 "activated double-positive thymocyte")
AnnotationAssertion(rdfs:label obo:CL_0002428 "double-positive blast")
EquivalentClasses(obo:CL_0002428 ObjectIntersectionOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000586) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0008283)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002428 obo:CL_0000809)
SubClassOf(obo:CL_0002428 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002427))

# Class: obo:CL_0002429 (CD69-positive double-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002429 "A double-positive thymocyte that is CD69-positive and has begun positive selection.")
AnnotationAssertion(terms:contributor obo:CL_0002429 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002429 "2010-10-21T02:11:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002429 "T.DP69+.Th")
AnnotationAssertion(rdfs:label obo:CL_0002429 "CD69-positive double-positive thymocyte")
EquivalentClasses(obo:CL_0002429 ObjectIntersectionOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0043368) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002429 obo:CL_0000809)
SubClassOf(obo:CL_0002429 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002428))

# Class: obo:CL_0002430 (CD4-intermediate, CD8-positive double-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002430 "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002430 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002430 "2010-10-21T02:29:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002430 "T.4int8+.Th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002430 "T_4int8+_Th")
AnnotationAssertion(rdfs:label obo:CL_0002430 "CD4-intermediate, CD8-positive double-positive thymocyte")
EquivalentClasses(obo:CL_0002430 ObjectIntersectionOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0043368) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002430 obo:CL_0000809)
SubClassOf(obo:CL_0002430 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002429))

# Class: obo:CL_0002431 (CD4-positive, CD8-intermediate double-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002431 "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002431 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002431 "2010-10-21T02:29:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002431 "T.4+8int.Th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002431 "T_4+8int_Th")
AnnotationAssertion(rdfs:label obo:CL_0002431 "CD4-positive, CD8-intermediate double-positive thymocyte")
EquivalentClasses(obo:CL_0002431 ObjectIntersectionOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0043368) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000025402)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002431 obo:CL_0000809)
SubClassOf(obo:CL_0002431 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002429))

# Class: obo:CL_0002432 (CD24-positive, CD4 single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002432 "A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002432 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002432 "2010-10-21T02:43:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002432 "CD24-positive, CD4 single-positive semimature thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002432 "T.4SP24int.Th")
AnnotationAssertion(rdfs:comment obo:CL_0002432 "Described in the immgene database as being CD24-intermediate.")
AnnotationAssertion(rdfs:label obo:CL_0002432 "CD24-positive, CD4 single-positive thymocyte")
EquivalentClasses(obo:CL_0002432 ObjectIntersectionOf(obo:CL_0000810 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002432 obo:CL_0000810)
SubClassOf(obo:CL_0002432 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002433))

# Class: obo:CL_0002433 (CD69-positive, CD4-positive single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002433 "A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002433 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002433 "2010-10-21T02:46:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002433 "T.4SP69+.Th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002433 "intermediate CD4-single-positive")
AnnotationAssertion(rdfs:label obo:CL_0002433 "CD69-positive, CD4-positive single-positive thymocyte")
EquivalentClasses(obo:CL_0002433 ObjectIntersectionOf(obo:CL_0000810 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002433 obo:CL_0000810)
SubClassOf(obo:CL_0002433 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002431))

# Class: obo:CL_0002434 (CD24-positive, CD8 single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002434 "A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002434 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002434 "2010-10-21T02:59:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002434 "CD24-positive, CD8 single-positive semimature thymocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002434 "T.8SP24int.Th")
AnnotationAssertion(rdfs:comment obo:CL_0002434 "Described in the immgene database as being CD24-intermediate.")
AnnotationAssertion(rdfs:label obo:CL_0002434 "CD24-positive, CD8 single-positive thymocyte")
EquivalentClasses(obo:CL_0002434 ObjectIntersectionOf(obo:CL_0000811 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002434 obo:CL_0000811)
SubClassOf(obo:CL_0002434 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002435))

# Class: obo:CL_0002435 (CD69-positive, CD8-positive single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0002435 "A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002435 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002435 "2010-10-21T02:59:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002435 "T.8SP69+.Th")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002435 "intermediate CD8-single-positive")
AnnotationAssertion(rdfs:label obo:CL_0002435 "CD69-positive, CD8-positive single-positive thymocyte")
EquivalentClasses(obo:CL_0002435 ObjectIntersectionOf(obo:CL_0000811 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002435 obo:CL_0000811)
SubClassOf(obo:CL_0002435 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002430))

# Class: obo:CL_0002436 (mature CD4 single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002436 "A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002436 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002436 "2010-10-21T03:31:19Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002436 "T.4SP24-.Th")
AnnotationAssertion(rdfs:label obo:CL_0002436 "mature CD4 single-positive thymocyte")
EquivalentClasses(obo:CL_0002436 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002436 obo:CL_0000624)
SubClassOf(obo:CL_0002436 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002432))

# Class: obo:CL_0002437 (mature CD8 single-positive thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002437 "A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor.")
AnnotationAssertion(terms:contributor obo:CL_0002437 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002437 "2010-10-21T03:51:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002437 "T.8SP24-.Th")
AnnotationAssertion(rdfs:label obo:CL_0002437 "mature CD8 single-positive thymocyte")
EquivalentClasses(obo:CL_0002437 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042105) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001932)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002437 obo:CL_0000625)
SubClassOf(obo:CL_0002437 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002434))

# Class: obo:CL_0002438 (NK1.1-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002438 "A mature NK cell that is NK1.1-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002438 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002438 "2010-10-25T03:18:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002438 "NK.sp")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002438 "NK1.1-positive NK cell")
AnnotationAssertion(rdfs:comment obo:CL_0002438 "Note: Nk1.1 expression is restricted to C57BL strains of laboratory mice.")
AnnotationAssertion(rdfs:label obo:CL_0002438 "NK1.1-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002438 ObjectIntersectionOf(obo:CL_0000824 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002977) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002439 (NKGA2-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002439 "A NK1.1-positive T cell that is NKGA2-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002439 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002439 "2010-10-25T03:31:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002439 "NK.G2A+.SP")
AnnotationAssertion(rdfs:label obo:CL_0002439 "NKGA2-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002439 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002023) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002440 (Ly49D-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002440 "A NK1.1-positive T cell that is Ly49D-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002440 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002440 "2010-10-25T03:36:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002440 "NK.49D+.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002440 "Ly49D-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002440 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009619) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002441 (CD94-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002441 "A NK1.1-positive T cell that is CD94-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002441 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002441 "2010-10-25T03:36:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002441 "NK.94+.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002441 "CD94-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002441 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001402) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002442 (CD94-negative, Ly49CI-negative natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002442 "A NK1.1-positive T cell that is CD94-negative and Ly49Cl-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002442 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002442 "2010-10-25T03:56:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002442 "CD94- Ly49I-negative NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002442 "NK.49Cl-94-.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002442 "CD94-negative, Ly49CI-negative natural killer cell, mouse")
EquivalentClasses(obo:CL_0002442 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001402) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009618) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002443 (Ly49CI-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002443 "A NK1.1-positive T cell that is Ly49Cl-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002443 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002443 "2010-10-25T03:36:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002443 "Ly49I-positive NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002443 "NK.49Cl+.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002443 "Ly49CI-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002443 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009618) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002444 (Ly49H-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002444 "A NK1.1-positive T cell that is Ly49H-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002444 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002444 "2010-10-25T03:36:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002444 "LyH49H-positive")
AnnotationAssertion(rdfs:label obo:CL_0002444 "Ly49H-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002444 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009623) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002445 (Ly49D-negative natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002445 "A NK1.1-positive T cell that is Ly49D-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002445 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002445 "2010-10-25T03:39:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002445 "NK.49D-.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002445 "Ly49D-negative natural killer cell, mouse")
EquivalentClasses(obo:CL_0002445 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009619) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002446 (Ly49CI-negative natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002446 "A NK1.1-positive T cell that is Ly49Cl-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002446 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002446 "2010-10-25T03:52:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002446 "Ly49I-negative NK cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002446 "NK.49Cl-.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002446 "Ly49CI-negative natural killer cell, mouse")
EquivalentClasses(obo:CL_0002446 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009618) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002447 (CD94-negative natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002447 "A NK1.1-positive T cell that is CD94-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002447 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002447 "2010-10-25T03:54:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002447 "NK.94-.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002447 "CD94-negative natural killer cell, mouse")
EquivalentClasses(obo:CL_0002447 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001402) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002448 (Ly49H-negative natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002448 "A NK1.1-positive T cell that is Ly49H-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002448 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002448 "2010-10-25T03:42:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002448 "LyH49H-negative")
AnnotationAssertion(rdfs:label obo:CL_0002448 "Ly49H-negative natural killer cell, mouse")
EquivalentClasses(obo:CL_0002448 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009623) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002449 (CD94-positive Ly49CI-positive natural killer cell, mouse)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002449 "A NK1.1-positive T cell that is CD94-positive and Ly49Cl-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002449 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002449 "2010-10-25T03:56:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002449 "NK.49Cl+94+.Sp")
AnnotationAssertion(rdfs:label obo:CL_0002449 "CD94-positive Ly49CI-positive natural killer cell, mouse")
EquivalentClasses(obo:CL_0002449 ObjectIntersectionOf(obo:CL_0002438 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009618) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090)))

# Class: obo:CL_0002450 (tether cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cvs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:9398434") obo:IAO_0000115 obo:CL_0002450 "A specialized hair cell that has an elongated kinocilium upon which an otolith accretes. The tether cell then anchors the otolith in place.")
AnnotationAssertion(terms:contributor obo:CL_0002450 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002450 "2010-11-10T01:41:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002450 "tether cell")
SubClassOf(obo:CL_0002450 obo:CL_0002374)

# Class: obo:CL_0002451 (mammary stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:hjd") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15987436") Annotation(oboInOwl:hasDbXref "PMID:16397499") Annotation(oboInOwl:hasDbXref "PMID:17851544") obo:IAO_0000115 obo:CL_0002451 "A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi.")
AnnotationAssertion(terms:contributor obo:CL_0002451 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002451 "2010-11-10T01:46:51Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002451 "mammary stem cell")
SubClassOf(obo:CL_0002451 obo:CL_0000048)

# Class: obo:CL_0002452 (obo:CL_0002452)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002452 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002452 obo:CL_0000134)
AnnotationAssertion(owl:deprecated obo:CL_0002452 "true"^^xsd:boolean)

# Class: obo:CL_0002453 (oligodendrocyte precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16367798") Annotation(oboInOwl:hasDbXref "PMID:20142420") Annotation(oboInOwl:hasDbXref "PMID:31583586") Annotation(oboInOwl:hasDbXref "PMID:31726662") Annotation(oboInOwl:hasDbXref "PMID:37653126") obo:IAO_0000115 obo:CL_0002453 "A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2.")
AnnotationAssertion(terms:contributor obo:CL_0002453 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:9780702028991") Annotation(oboInOwl:hasDbXref "PMID:10704434") Annotation(oboInOwl:hasDbXref "PMID:2182078") terms:description obo:CL_0002453 "This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991).")
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002453 "2010-11-10T02:51:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002453 "MESH:D000073637")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14501223") oboInOwl:hasRelatedSynonym obo:CL_0002453 "NG2 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2182078") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002453 "O2-A")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14501223") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002453 "OPC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23516142") oboInOwl:hasRelatedSynonym obo:CL_0002453 "Polydendrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002453 "oligodendrocyte precursor cell")
SubClassOf(obo:CL_0002453 obo:CL_0000123)
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:BFO_0000050 obo:CL_0000125))
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000047))
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000339))
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_4023059))
SubClassOf(obo:CL_0002453 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030154))

# Class: obo:CL_0002454 (CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002454 "CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002454 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002454 "2010-11-22T01:10:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002454 "DC.8-4-11b+")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002454 "spleen double-negative dendritic cell")
AnnotationAssertion(rdfs:label obo:CL_0002454 "CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell")
EquivalentClasses(obo:CL_0002454 ObjectIntersectionOf(obo:CL_0002465 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002454 obo:CL_0002465)

# Class: obo:CL_0002455 (CD8-alpha-negative plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002455 "A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-negative and CD4-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002455 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002455 "2010-11-22T01:27:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002455 "DC.pDC.8-")
AnnotationAssertion(rdfs:label obo:CL_0002455 "CD8-alpha-negative plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0002455 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002455 obo:CL_0000989)

# Class: obo:CL_0002456 (CD8-alpha-positive plasmacytoid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002456 "A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-positive and CD4-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002456 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002456 "2010-11-22T01:23:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002456 "DC.pDC.8+")
AnnotationAssertion(rdfs:label obo:CL_0002456 "CD8-alpha-positive plasmacytoid dendritic cell")
EquivalentClasses(obo:CL_0002456 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002456 obo:CL_0000989)

# Class: obo:CL_0002457 (epidermal Langerhans cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002457 "A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002457 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002457 "2010-11-22T03:57:57Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002457 "epidermal Langerhans cell")
EquivalentClasses(obo:CL_0002457 ObjectIntersectionOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002457 obo:CL_0000453)

# Class: obo:CL_0002458 (langerin-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002458 "A dermal dendritic cell that is langerin-positive and CD103-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002458 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002458 "2010-11-22T04:06:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002458 "langerin-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002458 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001010)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002458 obo:CL_0001006)

# Class: obo:CL_0002459 (langerin-negative dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002459 "A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002459 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002459 "2010-11-22T04:09:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002459 "langerin-negative dermal dendritic cell")
EquivalentClasses(obo:CL_0002459 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002459 obo:CL_0001006)

# Class: obo:CL_0002460 (CD8-alpha-negative thymic conventional dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19273629") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002460 "A conventional thymic dendritic cell that is CD8-alpha-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002460 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002460 "2010-11-23T10:58:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002460 "DC.8-.Th")
AnnotationAssertion(rdfs:label obo:CL_0002460 "CD8-alpha-negative thymic conventional dendritic cell")
EquivalentClasses(obo:CL_0002460 ObjectIntersectionOf(obo:CL_0000941 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002460 obo:CL_0000941)

# Class: obo:CL_0002461 (CD103-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002461 "A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002461 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002461 "2010-11-23T01:32:43Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002461 "CD103-positive dendritic cell")
EquivalentClasses(obo:CL_0002461 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001010)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002461 obo:CL_0000990)
SubClassOf(obo:CL_0002461 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0002462 (adipose dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002462 "A F4/80-negative dendritic cell located in adipose tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002462 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002462 "2010-11-23T01:38:21Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002462 "adipose dendritic cell")
EquivalentClasses(obo:CL_0002462 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001013) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002462 obo:CL_0000990)
SubClassOf(obo:CL_0002462 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010))

# Class: obo:CL_0002463 (SIRPa-positive adipose dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002463 "An adipose dendritic cell that is SIRPa-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002463 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002463 "2010-11-23T01:40:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002463 "DC.SIRPa+.Ad")
AnnotationAssertion(rdfs:label obo:CL_0002463 "SIRPa-positive adipose dendritic cell")
EquivalentClasses(obo:CL_0002463 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001968)))
SubClassOf(obo:CL_0002463 obo:CL_0002462)

# Class: obo:CL_0002464 (SIRPa-negative adipose dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002464 "An adipose dendritic cell that is SIRPa-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002464 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002464 "2010-11-23T01:40:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002464 "DC.SIRPa-.Ad")
AnnotationAssertion(rdfs:label obo:CL_0002464 "SIRPa-negative adipose dendritic cell")
EquivalentClasses(obo:CL_0002464 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001968)))
SubClassOf(obo:CL_0002464 obo:CL_0002462)

# Class: obo:CL_0002465 (CD11b-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002465 "A conventional dendritic cell that expresses CD11b (ITGAM).")
AnnotationAssertion(terms:contributor obo:CL_0002465 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002465 "2010-11-23T01:50:05Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002465 "CD11b-positive dendritic cell")
EquivalentClasses(obo:CL_0002465 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002465 obo:CL_0000990)

# Class: obo:CL_0002466 (small intestine serosal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002466 "A CD11b-positive dendritic cell located in the serosal portion of the small intestine epithelium. This cell type is CD45-positive, MHC-II-positive, CD11c-low, CD103-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002466 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002466 "2010-11-23T02:00:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002466 "DC.11cloSer.SI")
AnnotationAssertion(rdfs:label obo:CL_0002466 "small intestine serosal dendritic cell")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0002466 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0002466 ObjectIntersectionOf(obo:CL_0002465 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001206) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001013)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002466 obo:CL_0002465)

# Class: obo:CL_0002467 (Gr1-high myeloid suppressor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002467 "A myeloid suppressor cell that is Gr1-high and CD11c-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002467 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002467 "2010-11-23T02:15:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002467 "MDS.Gr1hi")
AnnotationAssertion(rdfs:label obo:CL_0002467 "Gr1-high myeloid suppressor cell")
EquivalentClasses(obo:CL_0002467 ObjectIntersectionOf(obo:CL_0000889 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002980)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002467 obo:CL_0000889)

# Class: obo:CL_0002468 (Gr1-low myeloid suppressor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002468 "A myeloid suppressor cell that is Gr1-low and CD11c-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002468 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002468 "2010-11-23T02:19:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002468 "MDS.Gr1lo")
AnnotationAssertion(rdfs:label obo:CL_0002468 "Gr1-low myeloid suppressor cell")
EquivalentClasses(obo:CL_0002468 ObjectIntersectionOf(obo:CL_0000889 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002980)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002468 obo:CL_0000889)

# Class: obo:CL_0002469 (MHC-II-negative classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002469 "Gr1-high monocyte that lacks MHC-II receptor complex.")
AnnotationAssertion(terms:contributor obo:CL_0002469 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002469 "2010-11-23T03:27:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002469 "Mo.6C+II-")
AnnotationAssertion(rdfs:label obo:CL_0002469 "MHC-II-negative classical monocyte")
EquivalentClasses(obo:CL_0002469 ObjectIntersectionOf(obo:CL_0002395 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002469 obo:CL_0002395)

# Class: obo:CL_0002470 (MHC-II-positive classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002470 "Gr1-high monocyte that has a MHC-II receptor complex.")
AnnotationAssertion(terms:contributor obo:CL_0002470 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002470 "2010-11-23T03:30:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002470 "Mo.6c+II")
AnnotationAssertion(rdfs:label obo:CL_0002470 "MHC-II-positive classical monocyte")
EquivalentClasses(obo:CL_0002470 ObjectIntersectionOf(obo:CL_0002395 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002470 obo:CL_0002395)

# Class: obo:CL_0002471 (MHC-II-negative non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002471 "Gr1-low non-classical monocyte that lacks expression of a MHC-II complex.")
AnnotationAssertion(terms:contributor obo:CL_0002471 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002471 "2010-11-23T03:38:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002471 "Mo.6C-II-")
AnnotationAssertion(rdfs:label obo:CL_0002471 "MHC-II-negative non-classical monocyte")
EquivalentClasses(obo:CL_0002471 ObjectIntersectionOf(obo:CL_0002058 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002471 obo:CL_0002058)

# Class: obo:CL_0002472 (MHC-II-low non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002472 "Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex.")
AnnotationAssertion(terms:contributor obo:CL_0002472 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002472 "2010-11-23T03:47:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002472 "Mo.6C-IIint")
AnnotationAssertion(rdfs:label obo:CL_0002472 "MHC-II-low non-classical monocyte")
EquivalentClasses(obo:CL_0002472 ObjectIntersectionOf(obo:CL_0002058 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002472 obo:CL_0002058)

# Class: obo:CL_0002473 (MHC-II-high non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002473 "Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex.")
AnnotationAssertion(terms:contributor obo:CL_0002473 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002473 "2010-11-23T03:47:55Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002473 "Mo.6C-II+")
AnnotationAssertion(rdfs:label obo:CL_0002473 "MHC-II-high non-classical monocyte")
EquivalentClasses(obo:CL_0002473 ObjectIntersectionOf(obo:CL_0002058 ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002473 obo:CL_0002058)

# Class: obo:CL_0002474 (lymphoid MHC-II-negative classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002474 "A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high.")
AnnotationAssertion(terms:contributor obo:CL_0002474 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002474 "2010-11-23T04:00:52Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002474 "lymphoid MHC-II-negative classical monocyte")
EquivalentClasses(obo:CL_0002474 ObjectIntersectionOf(obo:CL_0002469 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002474 obo:CL_0002469)

# Class: obo:CL_0002475 (lymphoid MHC-II-negative non-classical monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002475 "A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high.")
AnnotationAssertion(terms:contributor obo:CL_0002475 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002475 "2010-11-23T04:09:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002475 "lymphoid MHC-II-negative non-classical monocyte")
EquivalentClasses(obo:CL_0002475 ObjectIntersectionOf(obo:CL_0002471 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012)))
SubClassOf(obo:CL_0002475 obo:CL_0002471)

# Class: obo:CL_0002476 (bone marrow macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002476 "A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002476 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002476 "2010-11-23T04:19:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002476 "BTO:0004732")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002476 "MF.BM")
AnnotationAssertion(rdfs:label obo:CL_0002476 "bone marrow macrophage")
EquivalentClasses(obo:CL_0002476 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002980) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002476 obo:CL_0000864)
SubClassOf(obo:CL_0002476 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371))

# Class: obo:CL_0002477 (adipose macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002477 "A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002477 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002477 "2010-11-23T04:31:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002477 "adipose macrophage")
EquivalentClasses(obo:CL_0002477 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001968)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002477 obo:CL_0000864)

# Class: obo:CL_0002478 (F4/80-negative adipose macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002478 "An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions.")
AnnotationAssertion(terms:contributor obo:CL_0002478 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002478 "2010-11-23T04:40:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002478 "MF.Autofl.Ad")
AnnotationAssertion(rdfs:label obo:CL_0002478 "F4/80-negative adipose macrophage")
EquivalentClasses(obo:CL_0002478 ObjectIntersectionOf(obo:CL_0002477 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002478 obo:CL_0002477)

# Class: obo:CL_0002479 (F4/80-positive adipose macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002479 "An adipose macrophage that does not express MHC-II but is F4/80-positive.")
AnnotationAssertion(terms:contributor obo:CL_0002479 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002479 "2010-11-23T04:35:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002479 "MF.F480+.Ad")
AnnotationAssertion(rdfs:label obo:CL_0002479 "F4/80-positive adipose macrophage")
EquivalentClasses(obo:CL_0002479 ObjectIntersectionOf(obo:CL_0002477 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002479 obo:CL_0002477)

# Class: obo:CL_0002480 (nasal mucosa goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002480 "A goblet cell located in the nasal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002480 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002480 "2010-12-03T03:03:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002480 "MP:0002262")
AnnotationAssertion(rdfs:label obo:CL_0002480 "nasal mucosa goblet cell")
EquivalentClasses(obo:CL_0002480 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001826)))
SubClassOf(obo:CL_0002480 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005384))

# Class: obo:CL_0002481 (peritubular myoid cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0006420") obo:IAO_0000115 obo:CL_0002481 "The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule.")
AnnotationAssertion(terms:contributor obo:CL_0002481 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002481 "2010-12-03T03:11:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002481 "peritubular myoid cell")
EquivalentClasses(obo:CL_0002481 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001343)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002481 obo:CL_0000185)

# Class: obo:CL_0002482 (dermal melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0009386") obo:IAO_0000115 obo:CL_0002482 "A melanocyte that produces pigment in the dermis.")
AnnotationAssertion(terms:contributor obo:CL_0002482 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002482 "2010-12-03T03:17:05Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002482 "dermal melanocyte")
EquivalentClasses(obo:CL_0002482 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067)))

# Class: obo:CL_0002483 (hair follicle melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0004381") obo:IAO_0000115 obo:CL_0002483 "A melanocyte that produces pigment within the hair follicle.")
AnnotationAssertion(terms:contributor obo:CL_0002483 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002483 "2010-12-03T03:17:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002483 "hair follicle melanocyte")
EquivalentClasses(obo:CL_0002483 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002483 obo:CL_0000148)

# Class: obo:CL_0002484 (epithelial melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0009388") obo:IAO_0000115 obo:CL_0002484 "A melanocyte that produces pigment in the epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002484 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002484 "2010-12-03T03:17:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002484 "The text defintion reference to the MP term appears to reference an epidermal melanocyte term. This term represents any melanocyte in any epithelium.")
AnnotationAssertion(rdfs:label obo:CL_0002484 "epithelial melanocyte")
EquivalentClasses(obo:CL_0002484 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000483)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002484 obo:CL_0000148)

# Class: obo:CL_0002485 (retinal melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0010190") obo:IAO_0000115 obo:CL_0002485 "A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002485 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002485 "2010-12-03T03:25:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002485 "retinal melanocyte")
EquivalentClasses(obo:CL_0002485 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966)))

# Class: obo:CL_0002486 (strial intermediate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0000048") obo:IAO_0000115 obo:CL_0002486 "A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) .")
AnnotationAssertion(terms:contributor obo:CL_0002486 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002486 "2010-12-03T03:29:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002486 "strial intermediate cell")
EquivalentClasses(obo:CL_0002486 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002282)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002486 obo:CL_0000148)
SubClassOf(obo:CL_0002486 obo:CL_0002491)

# Class: obo:CL_0002487 (cutaneous/subcutaneous mechanoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0000973") obo:IAO_0000115 obo:CL_0002487 "A neuronal receptor that respond to mechanical pressure or distortion in the skin.")
AnnotationAssertion(terms:contributor obo:CL_0002487 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002487 "2010-12-06T02:53:30Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002487 "cutaneous/subcutaneous mechanoreceptor cell")
SubClassOf(obo:CL_0002487 obo:CL_0000199)

# Class: obo:CL_0002488 (trophoblast giant cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0001714") Annotation(oboInOwl:hasDbXref "MP:19876834") obo:IAO_0000115 obo:CL_0002488 "A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta.")
AnnotationAssertion(terms:contributor obo:CL_0002488 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002488 "2010-12-06T02:55:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002488 "giant trophoblast cell")
AnnotationAssertion(rdfs:label obo:CL_0002488 "trophoblast giant cell")
EquivalentClasses(obo:CL_0002488 ObjectIntersectionOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000586) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001974)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002488 obo:CL_0000351)

# Class: obo:CL_0002489 (double negative thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0002407") obo:IAO_0000115 obo:CL_0002489 "A thymocyte that lacks expression of CD4 and CD8.")
AnnotationAssertion(terms:contributor obo:CL_0002489 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002489 "2010-12-06T03:03:38Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0002407") oboInOwl:hasExactSynonym obo:CL_0002489 "CD4-CD8- T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002489 "double negative T cell")
AnnotationAssertion(rdfs:comment obo:CL_0002489 "These are precursors to mature T cells; normally, they do not circulate, but are found in the thymus and they have not undergone rearrangement of the alpha and beta T cell receptor genes.")
AnnotationAssertion(rdfs:label obo:CL_0002489 "double negative thymocyte")
EquivalentClasses(obo:CL_0002489 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402)))

# Class: obo:CL_0002490 (organ of Corti supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0004300") obo:IAO_0000115 obo:CL_0002490 "A supporting cell of the organ of Corti.")
AnnotationAssertion(terms:contributor obo:CL_0002490 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002490 "2010-12-06T03:09:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002490 "organ of Corti supporting cell")
EquivalentClasses(obo:CL_0002490 ObjectIntersectionOf(obo:CL_0005014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002227)))
SubClassOf(obo:CL_0002490 obo:CL_0002315)

# Class: obo:CL_0002491 (auditory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002491 "A specialized cell involved in auditory sensory perception.")
AnnotationAssertion(terms:contributor obo:CL_0002491 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002491 "2010-12-06T03:18:43Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002491 "auditory epithelial cell")
EquivalentClasses(obo:CL_0002491 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050910)))
SubClassOf(obo:CL_0002491 obo:CL_0000098)

# Class: obo:CL_0002492 (strial marginal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0004366") obo:IAO_0000115 obo:CL_0002492 "A polarized columnar cell that covesr the lateral surface of the cochlear duct, secretes potassium ions and forms a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria.")
AnnotationAssertion(terms:contributor obo:CL_0002492 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002492 "2010-12-06T03:20:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002492 "strial marginal cell")
SubClassOf(obo:CL_0002492 obo:CL_0002491)

# Class: obo:CL_0002493 (strial basal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0004365") obo:IAO_0000115 obo:CL_0002493 "A polarized cell that is juxtaposed to fibrocytes in the underlying spiral ligament. This cell type secretes potassium ions derived from fibrocytes through gap junctions.")
AnnotationAssertion(terms:contributor obo:CL_0002493 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002493 "2010-12-06T03:26:53Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002493 "Basal cells form a multi-layered epithelial barrier that separates the extracellular spaces of the stria vascularis and the spiral ligament[PMID:18353863]")
AnnotationAssertion(rdfs:label obo:CL_0002493 "strial basal cell")
SubClassOf(obo:CL_0002493 obo:CL_0002491)
SubClassOf(obo:CL_0002493 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002282))

# Class: obo:CL_0002494 (cardiocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002494 "A cell located in the heart, including both muscle and non muscle cells.")
AnnotationAssertion(terms:contributor obo:CL_0002494 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002494 "2010-12-07T09:37:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002494 "BTO:0001539")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002494 "CALOHA:TS-0115")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002494 "FMA:83808")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002494 "FMA:84791")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002494 "heart cell")
AnnotationAssertion(rdfs:comment obo:CL_0002494 "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.")
AnnotationAssertion(rdfs:label obo:CL_0002494 "cardiocyte")
EquivalentClasses(obo:CL_0002494 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007100)))

# Class: obo:CL_0002495 (fetal cardiomyocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0008788") obo:IAO_0000115 obo:CL_0002495 "A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte.")
AnnotationAssertion(terms:contributor obo:CL_0002495 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002495 "2010-12-07T09:50:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002495 "embryonic cardiomyocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002495 "neonatal cardiomyocyte")
AnnotationAssertion(rdfs:label obo:CL_0002495 "fetal cardiomyocyte")
SubClassOf(obo:CL_0002495 obo:CL_0000746)

# Class: obo:CL_0002496 (intraepithelial lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0008894") obo:IAO_0000115 obo:CL_0002496 "A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response.")
AnnotationAssertion(terms:contributor obo:CL_0002496 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002496 "2010-12-07T09:54:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002496 "MESH:D000075942")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002496 "IEL")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002496 "intraepithelial T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002496 "intraepithelial T-cell")
AnnotationAssertion(rdfs:label obo:CL_0002496 "intraepithelial lymphocyte")
EquivalentClasses(obo:CL_0002496 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002496 obo:CL_0002419)

# Class: obo:CL_0002497 (primary trophoblast giant cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC85124") obo:IAO_0000115 obo:CL_0002497 "A trophoblast giant cell derived from the mural trophectoderm.")
AnnotationAssertion(terms:contributor obo:CL_0002497 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002497 "2010-12-07T10:07:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002497 "EMAPA:16066")
AnnotationAssertion(rdfs:label obo:CL_0002497 "primary trophoblast giant cell")
SubClassOf(obo:CL_0002497 obo:CL_0002488)

# Class: obo:CL_0002498 (secondary trophoblast giant cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMCID:PMC85124") obo:IAO_0000115 obo:CL_0002498 "A trophoblast giant cell that is derived from ectoplacental cone and, later in gestation, the spongiotrophoblast.")
AnnotationAssertion(terms:contributor obo:CL_0002498 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002498 "2010-12-07T10:07:52Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002498 "secondary trophoblast giant cell")
SubClassOf(obo:CL_0002498 obo:CL_0002488)

# Class: obo:CL_0002499 (spongiotrophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0008959") obo:IAO_0000115 obo:CL_0002499 "A trophoblast cell that arises in the junctional zone (basal plate) of the placenta.")
AnnotationAssertion(terms:contributor obo:CL_0002499 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002499 "2010-12-07T12:56:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002499 "spongiotrophoblast")
AnnotationAssertion(rdfs:label obo:CL_0002499 "spongiotrophoblast cell")
SubClassOf(obo:CL_0002499 obo:CL_0000351)
SubClassOf(obo:CL_0002499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004021))

# Class: obo:CL_0002500 (P enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:63418") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002500 "A P/D1 enteroendocrine cell that is Grimelius positive and stores bombesin-like polypeptide.")
AnnotationAssertion(terms:contributor obo:CL_0002500 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002500 "2010-12-07T03:42:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002500 "P enteroendocrine cell")
SubClassOf(obo:CL_0002500 obo:CL_0002268)

# Class: obo:CL_0002501 (type D1 enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:63207") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002501 "A P/D1 enteroendocrine cell that is argyrophilic and stores vasoactive intestinal polypeptide.")
AnnotationAssertion(terms:contributor obo:CL_0002501 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002501 "2010-12-07T03:42:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002501 "FMA:63207")
AnnotationAssertion(rdfs:label obo:CL_0002501 "type D1 enteroendocrine cell")
SubClassOf(obo:CL_0002501 obo:CL_0002268)

# Class: obo:CL_0002502 (type M enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_0002502 "An enteroendocrine cell of the small intestine that secretes motilin.")
AnnotationAssertion(terms:contributor obo:CL_0002502 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002502 "2010-12-07T03:55:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002502 "Mo enteroendocrine cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002502 "FMA:63420")
AnnotationAssertion(rdfs:label obo:CL_0002502 "type M enteroendocrine cell")
SubClassOf(obo:CL_0002502 obo:CL_0000164)
SubClassOf(obo:CL_0002502 obo:CL_0002272)
SubClassOf(obo:CL_0002502 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0002503 (adventitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002503 "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc")
AnnotationAssertion(terms:contributor obo:CL_0002503 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002503 "2010-12-07T04:03:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002503 "BTO:0002441")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002503 "FMA:84639")
AnnotationAssertion(rdfs:label obo:CL_0002503 "adventitial cell")
EquivalentClasses(obo:CL_0002503 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005742)))
SubClassOf(obo:CL_0002503 obo:CL_0000630)
SubClassOf(obo:CL_0002503 obo:CL_0002320)

# Class: obo:CL_0002504 (enteric smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002504 "A smooth muscle cell of the intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002504 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002504 "2011-01-17T03:39:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002504 "intestinal smooth muscle cell")
AnnotationAssertion(rdfs:label obo:CL_0002504 "enteric smooth muscle cell")
EquivalentClasses(obo:CL_0002504 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000160)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002504 obo:CL_0000192)

# Class: obo:CL_0002505 (liver CD103-negative dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002505 "A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II-positive and CD103-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002505 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002505 "2011-01-21T01:27:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002505 "DC.103-11b+.Lv")
AnnotationAssertion(rdfs:label obo:CL_0002505 "liver CD103-negative dendritic cell")
EquivalentClasses(obo:CL_0002505 ObjectIntersectionOf(obo:CL_0002454 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002505 obo:CL_0002454)

# Class: obo:CL_0002506 (liver CD103-positive dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002506 "A CD11b-positive dendritic cell that is CD11b-low, CD45-positive, MHC-II-high and CD103-positive that is located in the liver.")
AnnotationAssertion(terms:contributor obo:CL_0002506 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002506 "2011-01-21T01:27:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002506 "DC.103+11b-.Lv")
AnnotationAssertion(rdfs:label obo:CL_0002506 "liver CD103-positive dendritic cell")
EquivalentClasses(obo:CL_0002506 ObjectIntersectionOf(obo:CL_0002454 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002506 obo:CL_0002454)

# Class: obo:CL_0002507 (langerin-positive lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002507 "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002507 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002507 "2011-01-21T01:57:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002507 "langerin-positive lymph node dendritic cell")
EquivalentClasses(obo:CL_0002507 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001293)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002507 obo:CL_0000990)

# Class: obo:CL_0002508 (langerin-negative, CD103-negative lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002508 "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative.")
AnnotationAssertion(terms:contributor obo:CL_0002508 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002508 "2011-01-21T02:13:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002508 "langerin-negative, CD103-negative lymph node dendritic cell")
EquivalentClasses(obo:CL_0002508 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001010) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001293) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002508 obo:CL_0000990)

# Class: obo:CL_0002509 (CD103-positive, langerin-positive lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002509 "A langerin-positive lymph node dendritic cell that is CD103-positive and CD11b-low.")
AnnotationAssertion(terms:contributor obo:CL_0002509 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002509 "2011-01-21T02:07:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002509 "CD103-positive, langerin-positive lymph node dendritic cell")
EquivalentClasses(obo:CL_0002509 ObjectIntersectionOf(obo:CL_0002507 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002509 obo:CL_0002507)

# Class: obo:CL_0002510 (CD103-negative, langerin-positive lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002510 "A langerin-positive lymph node dendritic cell that is CD103-negative and CD11b-high.")
AnnotationAssertion(terms:contributor obo:CL_0002510 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002510 "2011-01-21T02:11:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002510 "CD103-negative, langerin-positive lymph node dendritic cell")
EquivalentClasses(obo:CL_0002510 ObjectIntersectionOf(obo:CL_0002507 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001010) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002510 obo:CL_0002507)

# Class: obo:CL_0002511 (CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002511 "A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-low.")
AnnotationAssertion(terms:contributor obo:CL_0002511 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002511 "2011-01-21T02:22:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002511 "CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell")
EquivalentClasses(obo:CL_0002511 ObjectIntersectionOf(obo:CL_0002508 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002511 obo:CL_0002508)

# Class: obo:CL_0002512 (CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002512 "A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-high.")
AnnotationAssertion(terms:contributor obo:CL_0002512 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002512 "2011-01-21T02:16:21Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002512 "CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell")
EquivalentClasses(obo:CL_0002512 ObjectIntersectionOf(obo:CL_0002508 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002512 obo:CL_0002508)

# Class: obo:CL_0002513 (Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002513 "A CD8-alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment.")
AnnotationAssertion(terms:contributor obo:CL_0002513 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002513 "2011-01-24T10:22:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002513 "tgd.vg5+.IEL")
AnnotationAssertion(rdfs:label obo:CL_0002513 "Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell")
SubClassOf(obo:CL_0002513 obo:CL_0000802)

# Class: obo:CL_0002514 (Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://www.immgen.org/index_content.html") obo:IAO_0000115 obo:CL_0002514 "A CD8-alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment.")
AnnotationAssertion(terms:contributor obo:CL_0002514 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002514 "2011-01-24T10:25:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002514 "tgd.vg5-.IEL")
AnnotationAssertion(rdfs:label obo:CL_0002514 "Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell")
SubClassOf(obo:CL_0002514 obo:CL_0000802)

# Class: obo:CL_0002515 (interrenal norepinephrine type cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:MH") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12668625") obo:IAO_0000115 obo:CL_0002515 "An interrenal chromaffin cell found in teleosts that contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002515 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002515 "2011-02-08T10:11:55Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002515 "interrenal noradrenaline type cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002515 "type n interrenal cell")
AnnotationAssertion(rdfs:label obo:CL_0002515 "interrenal norepinephrine type cell")
SubClassOf(obo:CL_0002515 obo:CL_0000459)
SubClassOf(obo:CL_0002515 obo:CL_0002516)

# Class: obo:CL_0002516 (interrenal chromaffin cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:MH") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12668625") obo:IAO_0000115 obo:CL_0002516 "A chromaffin cell interspersed among the interrenal epithelial layer of the anterior kidney of teloest fish.")
AnnotationAssertion(terms:contributor obo:CL_0002516 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002516 "2011-02-08T10:21:35Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002516 "interrenal chromaffin cell")
SubClassOf(obo:CL_0002516 obo:CL_0000166)

# Class: obo:CL_0002517 (interrenal epinephrin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:MH") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12668625") obo:IAO_0000115 obo:CL_0002517 "An interrenal chromaffin cell found in teleosts that contain small, homogeneous electron-lucent granules that are separated from the vesicular membrane by a visible halo.")
AnnotationAssertion(terms:contributor obo:CL_0002517 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002517 "2011-02-08T10:27:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002517 "type a interrenal cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0002517 "interrenal adrenaline secreting cell")
AnnotationAssertion(rdfs:label obo:CL_0002517 "interrenal epinephrin secreting cell")
SubClassOf(obo:CL_0002517 obo:CL_0000454)
SubClassOf(obo:CL_0002517 obo:CL_0002516)

# Class: obo:CL_0002518 (kidney epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "KUPO:SJ") obo:IAO_0000115 obo:CL_0002518 "An epithelial cell of the kidney.")
AnnotationAssertion(terms:contributor obo:CL_0002518 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002518 "2011-02-08T10:46:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002518 "KUPO:0001019")
AnnotationAssertion(rdfs:label obo:CL_0002518 "kidney epithelial cell")
EquivalentClasses(obo:CL_0002518 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002113)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002518 obo:CL_1000497)

# Class: obo:CL_0002519 (interrenal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mh") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12668625") obo:IAO_0000115 obo:CL_0002519 "An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type.")
AnnotationAssertion(terms:contributor obo:CL_0002519 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002519 "2011-02-08T11:03:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002519 "interrenal epithelial cell")
SubClassOf(obo:CL_0002519 obo:CL_0002518)

# Class: obo:CL_0002520 (nephrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") obo:IAO_0000115 obo:CL_0002520 "An insect excretory cell that regulates hemolymph composition by filtration and filtrate endocytosis.")
AnnotationAssertion(terms:contributor obo:CL_0002520 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002520 "2011-02-08T01:34:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002520 "BTO:0004597")
AnnotationAssertion(rdfs:label obo:CL_0002520 "nephrocyte")
SubClassOf(obo:CL_0002520 obo:CL_0002522)
SubClassOf(obo:CL_0002520 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))

# Class: obo:CL_0002521 (subcutaneous adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002521 "An adipocyte that is part of subcutaneous adipose tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002521 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002521 "2011-02-21T02:51:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002521 "subcutaneous fat cell")
AnnotationAssertion(rdfs:label obo:CL_0002521 "subcutaneous adipocyte")
EquivalentClasses(obo:CL_0002521 ObjectIntersectionOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002190)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002521 obo:CL_0000136)

# Class: obo:CL_0002522 (renal filtration cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002522 "A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both.")
AnnotationAssertion(terms:contributor obo:CL_0002522 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002522 "2011-02-08T01:37:59Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002522 "renal filtration cell")
SubClassOf(obo:CL_0002522 obo:CL_0000424)
SubClassOf(obo:CL_0002522 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001008))

# Class: obo:CL_0002523 (mesonephric podocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002523 "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.")
AnnotationAssertion(terms:contributor obo:CL_0002523 <https://orcid.org/0000-0002-2244-7917>)
AnnotationAssertion(terms:contributor obo:CL_0002523 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002523 "2011-02-08T01:58:30Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0001674") oboInOwl:hasExactSynonym obo:CL_0002523 "mesonephric glomerular visceral epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002523 "mesonephric podocyte")
EquivalentClasses(obo:CL_0002523 ObjectIntersectionOf(obo:CL_0000653 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000080)))
SubClassOf(obo:CL_0002523 obo:CL_0000653)

# Class: obo:CL_0002524 (disseminated nephrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") obo:IAO_0000115 obo:CL_0002524 "A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues.")
AnnotationAssertion(terms:contributor obo:CL_0002524 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002524 "2011-02-08T02:07:33Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002524 "disseminated nephrocyte")
SubClassOf(obo:CL_0002524 obo:CL_0002520)

# Class: obo:CL_0002525 (metanephric podocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002525 "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the metanephros.")
AnnotationAssertion(terms:contributor obo:CL_0002525 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002525 "2011-02-08T02:02:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/s004180050142") oboInOwl:hasExactSynonym obo:CL_0002525 "metanephric glomerular visceral epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002525 "metanephric podocyte")
EquivalentClasses(obo:CL_0002525 ObjectIntersectionOf(obo:CL_0000653 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000081)))
SubClassOf(obo:CL_0002525 obo:CL_0000653)

# Class: obo:CL_0002526 (CD14-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:19236899") Annotation(oboInOwl:hasDbXref "PMID:20309010") obo:IAO_0000115 obo:CL_0002526 "A dermal dendritic cell that is CD1a-negative and CD14-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002526 "CD14+ dermal DC")
AnnotationAssertion(rdfs:comment obo:CL_0002526 "They are also CD11c-positive, CD40-positive, CD85j-positive (ILT-2), CD163-positive, CD205-positive (DEC205), CD207-negative (langerin), CD209-positive (DC-SIGN), CD274-positive (PD-L1), CD324-negative (E-cadherin), Factor XIIIa-positive, LOX-I-positive, CLEC6-positive, Dectin-1-positive, and DCIR-positive. Upon stimulation, these cells are capable of producing IL1-beta, IL6, IL8, IL10, IL12p40, IL19, IL20, IL24, TGF-beta, TNF-alpha, GM-CSF, and MCP1. They reside in the dermis.")
AnnotationAssertion(rdfs:label obo:CL_0002526 "CD14-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002526 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002025) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045191)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002526 obo:CL_0001006)

# Class: obo:CL_0002527 (immature CD14-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002527 "An immature CD14-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:label obo:CL_0002527 "immature CD14-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002527 ObjectIntersectionOf(obo:CL_0002526 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002527 obo:CL_0002526)

# Class: obo:CL_0002528 (mature CD14-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002528 "A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive.")
AnnotationAssertion(rdfs:label obo:CL_0002528 "mature CD14-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002528 ObjectIntersectionOf(obo:CL_0002526 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002528 obo:CL_0002526)
SubClassOf(obo:CL_0002528 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002527))

# Class: obo:CL_0002529 (CD1a-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:20309010") obo:IAO_0000115 obo:CL_0002529 "A dermal dendritic cell that is CD1a-positive and CD14-negative.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002529 "CD1a+ dermal DC")
AnnotationAssertion(rdfs:comment obo:CL_0002529 "Reside in the dermis. They are also CD11c-positive, CD40-positive, CD207-negative (langerin), CD209-negative (DC-SIGN), and CD324-negative (E-cadherin). When activated, they are capable of producing CXCL8 (IL-8) and IL-15. Possibly a precursor of Langerhans cells or equivalent of langerin-positive dermal DCs in the mouse.")
AnnotationAssertion(rdfs:label obo:CL_0002529 "CD1a-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002529 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002025)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002529 obo:CL_0001006)

# Class: obo:CL_0002530 (immature CD1a-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002530 "An immature CD1a-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:label obo:CL_0002530 "immature CD1a-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002530 ObjectIntersectionOf(obo:CL_0002529 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002530 obo:CL_0002529)

# Class: obo:CL_0002531 (mature CD1a-positive dermal dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002531 "A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high.")
AnnotationAssertion(rdfs:label obo:CL_0002531 "mature CD1a-positive dermal dendritic cell")
EquivalentClasses(obo:CL_0002531 ObjectIntersectionOf(obo:CL_0002529 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002531 obo:CL_0002529)
SubClassOf(obo:CL_0002531 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002530))

# Class: obo:CL_0002532 (CD16-positive myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:17332250") obo:IAO_0000115 obo:CL_0002532 "A myeloid dendritic cell found in the blood that is CD16-positive.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002532 "CD16+ mDC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002532 "CD16-mDC")
AnnotationAssertion(rdfs:comment obo:CL_0002532 "Normally represent 65-75% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), CD289-positive (TLR9), and CD290-positive (TLR10) by RT-PCR [PMID:17332250]. Upon TLR stimulation, these cells are potent producers of TNF-alpha, while producing little CXCL8 (IL8).")
AnnotationAssertion(rdfs:label obo:CL_0002532 "CD16-positive myeloid dendritic cell")
EquivalentClasses(obo:CL_0002532 ObjectIntersectionOf(obo:CL_0000782 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002532 obo:CL_0000782)

# Class: obo:CL_0002533 (immature CD16-positive myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002533 "An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low.")
AnnotationAssertion(rdfs:label obo:CL_0002533 "immature CD16-positive myeloid dendritic cell")
EquivalentClasses(obo:CL_0002533 ObjectIntersectionOf(obo:CL_0002532 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002533 obo:CL_0002532)

# Class: obo:CL_0002534 (mature CD16-positive myeloid dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002534 "A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high.")
AnnotationAssertion(rdfs:label obo:CL_0002534 "mature CD16-positive myeloid dendritic cell")
EquivalentClasses(obo:CL_0002534 ObjectIntersectionOf(obo:CL_0002532 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002534 obo:CL_0002532)
SubClassOf(obo:CL_0002534 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002533))

# Class: obo:CL_0002535 (epithelial cell of cervix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002535 "An epithelial cell of the cervix.")
AnnotationAssertion(terms:contributor obo:CL_0002535 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002535 "2011-02-24T08:20:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "cervical canal epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "cervical canal of uterus epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "cervix epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "cervix of uterus epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "epithelial cell of cervical canal")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "epithelial cell of cervical canal of uterus")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "epithelial cell of cervix of uterus")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "epithelial cell of neck of uterus")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "epithelial cell of uterine cervix")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "neck of uterus epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") oboInOwl:hasExactSynonym obo:CL_0002535 "uterine cervix epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002535 "epithelial cell of cervix")
EquivalentClasses(obo:CL_0002535 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000002)))
SubClassOf(obo:CL_0002535 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004801))

# Class: obo:CL_0002536 (epithelial cell of amnion)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002536 "An epithelial cell that is part of the amnion.")
AnnotationAssertion(terms:contributor obo:CL_0002536 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002536 "2011-02-28T12:38:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002536 "amniotic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002536 "epithelial cell of amnion")
EquivalentClasses(obo:CL_0002536 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000305)))

# Class: obo:CL_0002537 (amnion mesenchymal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20446274") Annotation(oboInOwl:hasDbXref "PMID:21339039") obo:IAO_0000115 obo:CL_0002537 "A mesenchymal stem cell of the amnion membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002537 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002537 "2011-02-28T12:44:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002537 "amniotic membrane stem cell")
AnnotationAssertion(rdfs:label obo:CL_0002537 "amnion mesenchymal stem cell")
EquivalentClasses(obo:CL_0002537 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000305)))

# Class: obo:CL_0002538 (intrahepatic cholangiocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:23720296") obo:IAO_0000115 obo:CL_0002538 "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes.")
AnnotationAssertion(terms:contributor obo:CL_0002538 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002538 "2011-02-28T01:20:20Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23720296") oboInOwl:hasExactSynonym obo:CL_0002538 "small bile duct cholangiocyte")
AnnotationAssertion(rdfs:label obo:CL_0002538 "intrahepatic cholangiocyte")
EquivalentClasses(obo:CL_0002538 ObjectIntersectionOf(obo:CL_1000488 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004823)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002538 obo:CL_1000488)

# Class: obo:CL_0002539 (aortic smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002539 "A smooth muscle cell of the aorta.")
AnnotationAssertion(terms:contributor obo:CL_0002539 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002539 "2011-02-28T01:42:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002539 "BTO:0004577")
AnnotationAssertion(rdfs:label obo:CL_0002539 "aortic smooth muscle cell")
EquivalentClasses(obo:CL_0002539 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004178)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002539 obo:CL_0000359)

# Class: obo:CL_0002540 (mesenchymal stem cell of the bone marrow)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002540 "A mesenchymal stem cell that is part of the bone marrow.")
AnnotationAssertion(terms:contributor obo:CL_0002540 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002540 "2011-02-28T01:47:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002540 "mesenchymal stem cell of the bone marrow")
EquivalentClasses(obo:CL_0002540 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))

# Class: obo:CL_0002541 (chorionic membrane mesenchymal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002541 "A mesenchymal stem cell of the chorionic membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002541 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002541 "2011-02-28T03:04:35Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002541 "chorionic membrane mesenchymal stem cell")
EquivalentClasses(obo:CL_0002541 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003124)))

# Class: obo:CL_0002542 (obo:CL_0002542)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002542 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002542 obo:CL_1000413)
AnnotationAssertion(owl:deprecated obo:CL_0002542 "true"^^xsd:boolean)

# Class: obo:CL_0002543 (vein endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002543 "An endothelial cell that is part of the vein.")
AnnotationAssertion(terms:contributor obo:CL_0002543 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002543 "2011-02-28T03:48:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002543 "FMA:62104")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002543 "KUPO:0001099")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002543 "endothelial cell of vein")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002543 "venous endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_0002543 "vein endothelial cell")
EquivalentClasses(obo:CL_0002543 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001638)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002543 obo:CL_0000071)

# Class: obo:CL_0002544 (aortic endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002544 "An arterial endothelial cell that is part of the aorta endothelium.")
AnnotationAssertion(terms:contributor obo:CL_0002544 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002544 "2011-02-28T03:54:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002544 "BTO:0003245")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002544 "CALOHA:TS-0047")
AnnotationAssertion(rdfs:label obo:CL_0002544 "aortic endothelial cell")
SubClassOf(obo:CL_0002544 obo:CL_1000413)

# Class: obo:CL_0002545 (thoracic aorta endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002545 "An endothelial cell that is part of the thoracic endothelium.")
AnnotationAssertion(terms:contributor obo:CL_0002545 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002545 "2011-02-28T03:59:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002545 "thoracic aorta endothelial cell")
EquivalentClasses(obo:CL_0002545 ObjectIntersectionOf(obo:CL_0002544 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001515)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002545 obo:CL_0002544)

# Class: obo:CL_0002546 (embryonic blood vessel endothelial progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002546 "An endothelial progenitor cell that participates in angiogenesis during development.")
AnnotationAssertion(terms:contributor obo:CL_0002546 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002546 "2011-02-28T04:20:39Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002546 "See CL:0002619.")
AnnotationAssertion(rdfs:label obo:CL_0002546 "embryonic blood vessel endothelial progenitor cell")
SubClassOf(obo:CL_0002546 obo:CL_0000222)

# Class: obo:CL_0002547 (fibroblast of the aortic adventitia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002547 "A fibroblast of the aortic adventitia.")
AnnotationAssertion(terms:contributor obo:CL_0002547 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002547 "2011-02-28T04:43:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002547 "fibroblast of the aortic adventitia")
EquivalentClasses(obo:CL_0002547 ObjectIntersectionOf(obo:CL_1000306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004664)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002547 obo:CL_1000306)

# Class: obo:CL_0002548 (fibroblast of cardiac tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002548 "A fibroblast that is part of the heart.")
AnnotationAssertion(terms:contributor obo:CL_0002548 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002548 "2011-02-28T04:57:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002548 "cardiac fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0002548 "fibroblast of cardiac tissue")
EquivalentClasses(obo:CL_0002548 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000948)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002548 obo:CL_0000057)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002548 obo:CL_0002494)

# Class: obo:CL_0002549 (fibroblast of choroid plexus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002549 "A fibroblast that is part of the choroid plexus.")
AnnotationAssertion(terms:contributor obo:CL_0002549 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002549 "2011-02-28T05:01:39Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002549 "fibroblast of choroid plexus")
EquivalentClasses(obo:CL_0002549 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001886)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002549 obo:CL_0000057)

# Class: obo:CL_0002550 (fibroblast of the conjunctiva)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002550 "A fibroblast that is part of the conjuctiva of the eye.")
AnnotationAssertion(terms:contributor obo:CL_0002550 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002550 "2011-02-28T05:03:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002550 "fibroblast of the conjunctiva")
EquivalentClasses(obo:CL_0002550 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001811)))
SubClassOf(obo:CL_0002550 obo:CL_0000057)

# Class: obo:CL_0002551 (fibroblast of dermis)

AnnotationAssertion(terms:contributor obo:CL_0002551 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002551 "2011-02-28T05:05:33Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002551 "fibroblast of dermis")
EquivalentClasses(obo:CL_0002551 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002551 obo:CL_0002620)

# Class: obo:CL_0002552 (fibroblast of gingiva)

AnnotationAssertion(terms:contributor obo:CL_0002552 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002552 "2011-02-28T05:09:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002552 "fibroblast of gingiva")
EquivalentClasses(obo:CL_0002552 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001828)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002552 obo:CL_0000057)

# Class: obo:CL_0002553 (fibroblast of lung)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002553 "A fibroblast that is part of lung.")
AnnotationAssertion(terms:contributor obo:CL_0002553 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002553 "2011-02-28T05:11:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002553 "BTO:0000764")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002553 "CALOHA:TS-0575")
AnnotationAssertion(rdfs:label obo:CL_0002553 "fibroblast of lung")
EquivalentClasses(obo:CL_0002553 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002553 obo:CL_0000057)

# Class: obo:CL_0002554 (fibroblast of lymphatic vessel)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002554 "A fibroblast of the lymphatic system.")
AnnotationAssertion(terms:contributor obo:CL_0002554 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002554 "2011-02-28T05:16:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002554 "fibroblast of lymphatic vessel")
EquivalentClasses(obo:CL_0002554 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001473)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002554 obo:CL_0000057)

# Class: obo:CL_0002555 (fibroblast of mammary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002555 "A fibroblast that is part of the mammary gland.")
AnnotationAssertion(terms:contributor obo:CL_0002555 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002555 "2011-02-28T05:18:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002555 "fibroblast of mammary gland")
EquivalentClasses(obo:CL_0002555 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002555 obo:CL_0000057)

# Class: obo:CL_0002556 (fibroblast of periodontium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002556 "A fibroblast of the periodontium.")
AnnotationAssertion(terms:contributor obo:CL_0002556 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002556 "2011-02-28T05:19:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002556 "fibroblast of periodontium")
EquivalentClasses(obo:CL_0002556 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001758)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002556 obo:CL_0000057)

# Class: obo:CL_0002557 (fibroblast of pulmonary artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002557 "A fibroblast of pulmonary artery.")
AnnotationAssertion(terms:contributor obo:CL_0002557 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002557 "2011-02-28T05:22:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002557 "fibroblast of pulmonary artery")
EquivalentClasses(obo:CL_0002557 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002557 obo:CL_0000057)

# Class: obo:CL_0002558 (fibroblast of villous mesenchyme)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002558 "A fibroblast that is part of villous mesenchyme.")
AnnotationAssertion(terms:contributor obo:CL_0002558 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002558 "2011-02-28T05:24:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002558 "fibroblast of villous mesenchyme")
SubClassOf(obo:CL_0002558 obo:CL_0000057)
SubClassOf(obo:CL_0002558 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987))

# Class: obo:CL_0002559 (hair follicle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002559 "An animal cell that is part of a hair follicle.")
AnnotationAssertion(terms:contributor obo:CL_0002559 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002559 "2011-03-01T04:11:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002559 "hair follicle cell")
EquivalentClasses(obo:CL_0002559 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073)))

# Class: obo:CL_0002560 (inner root sheath cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002560 "An epithelial cell that resides in the inner root sheath of the hair follicle.")
AnnotationAssertion(terms:contributor obo:CL_0002560 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002560 "2011-03-01T04:27:51Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002560 "inner root sheath cell")
EquivalentClasses(obo:CL_0002560 ObjectIntersectionOf(obo:CL_0002559 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005941)))
SubClassOf(obo:CL_0002560 obo:CL_0000066)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002560 obo:CL_0002559)

# Class: obo:CL_0002561 (outer root sheath cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002561 "An epithelial cell that is part of the outer root sheath.")
AnnotationAssertion(terms:contributor obo:CL_0002561 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002561 "2011-03-01T04:29:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002561 "outer root sheath cell")
EquivalentClasses(obo:CL_0002561 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005942)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002561 obo:CL_0002559)

# Class: obo:CL_0002562 (hair germinal matrix cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002562 "An epidermal cell that is part of the germinal matrix.")
AnnotationAssertion(terms:contributor obo:CL_0002562 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002562 "2011-03-01T04:31:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002562 "trichocyte")
AnnotationAssertion(rdfs:label obo:CL_0002562 "hair germinal matrix cell")
EquivalentClasses(obo:CL_0002562 ObjectIntersectionOf(obo:CL_0000362 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006004)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002562 obo:CL_0000362)

# Class: obo:CL_0002563 (intestinal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002563 "An epithelial cell of the lining of the intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002563 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002563 "2011-03-01T05:18:31Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002563 "intestinal epithelial cell")
EquivalentClasses(obo:CL_0002563 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)))

# Class: obo:CL_0002564 (nucleus pulposus cell of intervertebral disc)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002564 "A connective tissue cell of the nucleus pulposus cell of intervertebral disc.")
AnnotationAssertion(terms:contributor obo:CL_0002564 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002564 "2011-03-02T02:12:23Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002564 "nucleus pulposus cell of intervertebral disc")
EquivalentClasses(obo:CL_0002564 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002242)))
SubClassOf(obo:CL_0002564 obo:CL_0002320)

# Class: obo:CL_0002565 (iris pigment epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002565 "A pigment cell located in the epithelium of the iris.")
AnnotationAssertion(terms:contributor obo:CL_0002565 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002565 "2011-03-01T05:28:52Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002565 "iris pigment epithelial cell")
EquivalentClasses(obo:CL_0002565 ObjectIntersectionOf(obo:CL_0000342 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002506)))
SubClassOf(obo:CL_0002565 obo:CL_0000066)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002565 obo:CL_0000342)

# Class: obo:CL_0002566 (dark melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002566 "A melanocyte that appears darker due to content or amount of melanin granules.")
AnnotationAssertion(terms:contributor obo:CL_0002566 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002566 "2011-03-01T05:57:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10985850") oboInOwl:hasExactSynonym obo:CL_0002566 "melanotic melanocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10985850") oboInOwl:hasExactSynonym obo:CL_0002566 "melanotic melanophore")
AnnotationAssertion(rdfs:label obo:CL_0002566 "dark melanocyte")
SubClassOf(obo:CL_0002566 obo:CL_0000148)

# Class: obo:CL_0002567 (light melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002567 "A melanocyte that appears lighter in color.")
AnnotationAssertion(terms:contributor obo:CL_0002567 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002567 "2011-03-01T05:58:23Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10985850") oboInOwl:hasExactSynonym obo:CL_0002567 "amelanotic melanocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10985850") oboInOwl:hasExactSynonym obo:CL_0002567 "amelanotic melanophore")
AnnotationAssertion(rdfs:label obo:CL_0002567 "light melanocyte")
SubClassOf(obo:CL_0002567 obo:CL_0000148)

# Class: obo:CL_0002568 (mesenchymal stem cell of Wharton's jelly)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002568 "A mesenchymal stem cell that is part of Wharton's jelly.")
AnnotationAssertion(terms:contributor obo:CL_0002568 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002568 "2011-03-01T09:51:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002568 "mesenchymal stem cell of Wharton's jelly")
SubClassOf(obo:CL_0002568 obo:CL_0002569)

# Class: obo:CL_0002569 (mesenchymal stem cell of umbilical cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002569 "A mesenchymal stem cell of the umbilical cord.")
AnnotationAssertion(terms:contributor obo:CL_0002569 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002569 "2011-03-01T09:55:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002569 "mesenchymal stem cell of umbilical cord")
EquivalentClasses(obo:CL_0002569 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003422)))

# Class: obo:CL_0002570 (mesenchymal stem cell of adipose tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002570 "A mesenchymal stem cell of adipose tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002570 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002570 "2011-03-01T09:57:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002570 "mesenchymal stem cell of adipose")
AnnotationAssertion(rdfs:label obo:CL_0002570 "mesenchymal stem cell of adipose tissue")
EquivalentClasses(obo:CL_0002570 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001013)))

# Class: obo:CL_0002571 (hepatic mesenchymal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002571 "A mesenchymal stem cell of liver.")
AnnotationAssertion(terms:contributor obo:CL_0002571 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002571 "2011-03-01T09:58:51Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002571 "hepatic mesenchymal stem cell")
EquivalentClasses(obo:CL_0002571 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002571 obo:CL_0000134)

# Class: obo:CL_0002572 (vertebral mesenchymal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002572 "A mesenchymal stem cell of the vertebrae.")
AnnotationAssertion(terms:contributor obo:CL_0002572 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002572 "2011-03-01T10:40:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002572 "vertebral mesenchymal stem cell")
EquivalentClasses(obo:CL_0002572 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002412)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002572 obo:CL_0000134)

# Class: obo:CL_0002573 (Schwann cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16807057") obo:IAO_0000115 obo:CL_0002573 "A glial cell that myelinates or ensheathes axons in the peripheral nervous system.")
AnnotationAssertion(terms:contributor obo:CL_0002573 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002573 "2011-03-02T01:19:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002573 "BTO:0001220")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002573 "CALOHA:TS-0898")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002573 "MESH:D012583")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32119275") Annotation(oboInOwl:hasDbXref "PMID:38638689") oboInOwl:hasExactSynonym obo:CL_0002573 "neurolemmocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16807057") rdfs:comment obo:CL_0002573 "A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle.")
AnnotationAssertion(rdfs:label obo:CL_0002573 "Schwann cell")
SubClassOf(obo:CL_0002573 obo:CL_0000125)
SubClassOf(obo:CL_0002573 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000010))

# Class: obo:CL_0002574 (stromal cell of pancreas)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002574 "A stromal cell of the pancreas.")
AnnotationAssertion(terms:contributor obo:CL_0002574 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002574 "2011-03-02T02:40:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002574 "stromal cell of pancreas")
EquivalentClasses(obo:CL_0002574 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002574 obo:CL_0000499)

# Class: obo:CL_0002575 (central nervous system pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002575 "A pericyte of the central nervous system.")
AnnotationAssertion(terms:contributor obo:CL_0002575 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002575 "2011-03-02T02:54:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002575 "central nervous system pericyte")
EquivalentClasses(obo:CL_0002575 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002575 obo:CL_0000669)

# Class: obo:CL_0002576 (perineurial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:tfm") Annotation(oboInOwl:hasDbXref "NCIT:C41442") Annotation(oboInOwl:hasDbXref "PMID:25818566") Annotation(oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Perineurium") obo:IAO_0000115 obo:CL_0002576 "A glial cell that is part of the perineurium. This cell type has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions. Perineurial cells historically have been referred to as fibroblasts because of shape; however, unlike fibroblasts, a perineurial cell: does not have a compact nucleus and large endoplasmic reticulum; does have a double basement membrane opposed to a single basal lamina; is carefully joined to other perineurial cells by tight junctions into a single sheet as opposed to arranged in a large mass; and finally, can surround a small axon bundle at a nerve terminal whereas a fibroblast cannot.")
AnnotationAssertion(terms:contributor obo:CL_0002576 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:contributor obo:CL_0002576 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002576 "2011-03-02T03:03:58Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25818566") oboInOwl:hasExactSynonym obo:CL_0002576 "perineurial glial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36244793") rdfs:comment obo:CL_0002576 "There are studies that largely accept the idea that the perineurial cell is a modified fibroblast with myofibroblastic features.")
AnnotationAssertion(rdfs:label obo:CL_0002576 "perineurial cell")
SubClassOf(obo:CL_0002576 obo:CL_0000125)
SubClassOf(obo:CL_0002576 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000121))

# Class: obo:CL_0002577 (placental epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002577 "An epithelial cell of the placenta.")
AnnotationAssertion(terms:contributor obo:CL_0002577 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002577 "2011-03-02T03:21:30Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002577 "placental epithelial cell")
EquivalentClasses(obo:CL_0002577 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002577 obo:CL_0000349)

# Class: obo:CL_0002578 (mesenteric preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002578 "A preadipocyte found in mesenteric tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002578 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002578 "2011-03-03T04:19:40Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002578 "mesenteric preadipocyte")
EquivalentClasses(obo:CL_0002578 ObjectIntersectionOf(obo:CL_0002334 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002095)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002578 obo:CL_0002334)

# Class: obo:CL_0002579 (omentum preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21484051") obo:IAO_0000115 obo:CL_0002579 "A preadipocyte that is part of an omentum.")
AnnotationAssertion(terms:contributor obo:CL_0002579 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002579 "2011-03-03T04:19:42Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002579 "omentum preadipocyte")
EquivalentClasses(obo:CL_0002579 ObjectIntersectionOf(obo:CL_0002334 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003688)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002579 obo:CL_0002334)

# Class: obo:CL_0002580 (preadipocyte of the breast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002580 "A preadipocyte that is part of the breast.")
AnnotationAssertion(terms:contributor obo:CL_0002580 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002580 "2011-03-03T04:19:46Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002580 "preadipocyte of the breast")
EquivalentClasses(obo:CL_0002580 ObjectIntersectionOf(obo:CL_0002334 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000310)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002580 obo:CL_0002334)

# Class: obo:CL_0002581 (perirenal preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20106964") Annotation(oboInOwl:hasDbXref "PMID:31079959") obo:IAO_0000115 obo:CL_0002581 "A preadipocyte that is part of a perirenal fat tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002581 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002581 "2011-03-03T04:20:04Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002581 "perirenal preadipocyte")
EquivalentClasses(obo:CL_0002581 ObjectIntersectionOf(obo:CL_0002334 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005406)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002581 obo:CL_0002334)

# Class: obo:CL_0002582 (visceral preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002582 "A preadipocyte that is part of visceral tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002582 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002582 "2011-03-03T04:32:56Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002582 "visceral preadipocyte")
SubClassOf(obo:CL_0002582 obo:CL_0002334)

# Class: obo:CL_0002583 (subcutaneous preadipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002583 "A preadipocyte that is part of subcutaneous tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002583 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002583 "2011-03-03T04:33:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002583 "subcutaneous preadipocyte")
EquivalentClasses(obo:CL_0002583 ObjectIntersectionOf(obo:CL_0002334 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002072)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002583 obo:CL_0002334)

# Class: obo:CL_0002584 (renal cortical epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002584 "An epithelial cell of the kidney cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002584 "KUPO:0001016")
AnnotationAssertion(rdfs:label obo:CL_0002584 "renal cortical epithelial cell")
EquivalentClasses(obo:CL_0002584 ObjectIntersectionOf(obo:CL_0002518 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001225)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002584 obo:CL_0002518)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002584 obo:CL_0002681)

# Class: obo:CL_0002585 (retinal blood vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002585 "A blood vessel endothelial cell that is part of the retina.")
AnnotationAssertion(terms:contributor obo:CL_0002585 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002585 "2011-03-06T03:28:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002585 "retinal blood vessel endothelial cell")
EquivalentClasses(obo:CL_0002585 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002585 obo:CL_0000071)

# Class: obo:CL_0002586 (retinal pigment epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002586 "An epithelial cell of the retinal pigmented epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002586 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002586 "2011-03-06T03:37:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002586 "BTO:0004910")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002586 "FMA:75802")
AnnotationAssertion(rdfs:label obo:CL_0002586 "retinal pigment epithelial cell")
EquivalentClasses(obo:CL_0002586 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001782)))
SubClassOf(obo:CL_0002586 obo:CL_0000149)
SubClassOf(obo:CL_0002586 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042470))

# Class: obo:CL_0002587 (obo:CL_0002587)

AnnotationAssertion(obo:IAO_0000231 obo:CL_0002587 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002587 obo:CL_0002140)
AnnotationAssertion(owl:deprecated obo:CL_0002587 "true"^^xsd:boolean)

# Class: obo:CL_0002588 (smooth muscle cell of the umbilical vein)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002588 "A smooth muscle cell of the umbilical vein.")
AnnotationAssertion(terms:contributor obo:CL_0002588 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002588 "2011-03-06T05:00:51Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002588 "smooth muscle cell of the umbilical vein")
EquivalentClasses(obo:CL_0002588 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002066)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002588 obo:CL_0000359)

# Class: obo:CL_0002589 (smooth muscle cell of the brachiocephalic vasculature)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002589 "A smooth muscle cell of the bachiocephalic vasculature.")
AnnotationAssertion(terms:contributor obo:CL_0002589 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002589 "2011-03-06T05:00:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002589 "smooth muscle cell of the brachiocephalic vasculature")
EquivalentClasses(obo:CL_0002589 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001529)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002589 obo:CL_0000359)

# Class: obo:CL_0002590 (smooth muscle cell of the brain vasculature)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002590 "A vascular associated smooth muscle cell of the brain vasculature.")
AnnotationAssertion(terms:contributor obo:CL_0002590 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002590 "2011-03-06T05:01:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002590 "smooth muscle cell of the brain vasculature")
EquivalentClasses(obo:CL_0002590 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000955)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002590 obo:CL_0000359)

# Class: obo:CL_0002591 (smooth muscle cell of the pulmonary artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002591 "A smooth muscle of the pulmonary artery.")
AnnotationAssertion(terms:contributor obo:CL_0002591 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002591 "2011-03-06T05:01:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002591 "BTO:0003336")
AnnotationAssertion(rdfs:label obo:CL_0002591 "smooth muscle cell of the pulmonary artery")
EquivalentClasses(obo:CL_0002591 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002012)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002591 obo:CL_0000359)

# Class: obo:CL_0002592 (smooth muscle cell of the coronary artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002592 "A smooth muscle cell of the coronary artery.")
AnnotationAssertion(terms:contributor obo:CL_0002592 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002592 "2011-03-06T05:01:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002592 "smooth muscle cell of the coronary artery")
EquivalentClasses(obo:CL_0002592 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001621)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002592 obo:CL_0000359)

# Class: obo:CL_0002593 (smooth muscle cell of the internal thoracic artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002593 "A smooth muscle of the internal thoracic artery.")
AnnotationAssertion(terms:contributor obo:CL_0002593 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002593 "2011-03-06T05:01:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002593 "smooth muscle cell of the internal thoracic artery")
EquivalentClasses(obo:CL_0002593 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002456)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002593 obo:CL_0000359)

# Class: obo:CL_0002594 (smooth muscle cell of the umbilical artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002594 "A smooth muscle cell of the umbilical artery.")
AnnotationAssertion(terms:contributor obo:CL_0002594 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002594 "2011-03-06T05:01:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002594 "smooth muscle cell of the umbilical artery")
EquivalentClasses(obo:CL_0002594 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001310)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002594 obo:CL_0000359)

# Class: obo:CL_0002595 (smooth muscle cell of the subclavian artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002595 "A smooth muscle cell of the subclavian artery.")
AnnotationAssertion(terms:contributor obo:CL_0002595 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002595 "2011-03-06T05:01:52Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002595 "smooth muscle cell of the subclavian artery")
EquivalentClasses(obo:CL_0002595 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001533)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002595 obo:CL_0000359)

# Class: obo:CL_0002596 (smooth muscle cell of the carotid artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002596 "Smooth muscle cell of the carotid artery.")
AnnotationAssertion(terms:contributor obo:CL_0002596 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002596 "2011-03-06T05:01:56Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002596 "smooth muscle cell of the carotid artery")
EquivalentClasses(obo:CL_0002596 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005396)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002596 obo:CL_0000359)

# Class: obo:CL_0002597 (smooth muscle cell of bladder)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GC:tfm") obo:IAO_0000115 obo:CL_0002597 "A smooth muscle cell of the bladder.")
AnnotationAssertion(terms:contributor obo:CL_0002597 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002597 "2011-03-06T05:43:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002597 "KUPO:0001122")
AnnotationAssertion(rdfs:label obo:CL_0002597 "smooth muscle cell of bladder")
EquivalentClasses(obo:CL_0002597 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001255)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002597 obo:CL_0000192)

# Class: obo:CL_0002598 (bronchial smooth muscle cell)

AnnotationAssertion(terms:contributor obo:CL_0002598 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002598 "2011-03-06T05:46:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002598 "BTO:0004402")
AnnotationAssertion(rdfs:label obo:CL_0002598 "bronchial smooth muscle cell")
EquivalentClasses(obo:CL_0002598 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002185)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002598 obo:CL_0000192)

# Class: obo:CL_0002599 (smooth muscle cell of the esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002599 "A smooth muscle cell of the esophagus.")
AnnotationAssertion(terms:contributor obo:CL_0002599 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002599 "2011-03-06T05:48:17Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002599 "smooth muscle cell of the esophagus")
EquivalentClasses(obo:CL_0002599 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001043)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002599 obo:CL_0000192)

# Class: obo:CL_0002600 (smooth muscle cell of trachea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002600 "A smooth muscle cell of the trachea.")
AnnotationAssertion(terms:contributor obo:CL_0002600 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002600 "2011-03-06T05:50:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002600 "smooth muscle cell of trachea")
EquivalentClasses(obo:CL_0002600 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003126)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002600 obo:CL_0000192)

# Class: obo:CL_0002601 (uterine smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002601 "A smooth muscle cell of the uterus.")
AnnotationAssertion(terms:contributor obo:CL_0002601 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002601 "2011-03-06T05:53:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002601 "uterine smooth muscle cell")
EquivalentClasses(obo:CL_0002601 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000995)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002601 obo:CL_0000192)

# Class: obo:CL_0002602 (annulus pulposus cell)

AnnotationAssertion(terms:contributor obo:CL_0002602 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002602 "2011-03-06T06:50:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002602 "anulus pulposus cell")
AnnotationAssertion(rdfs:label obo:CL_0002602 "annulus pulposus cell")
EquivalentClasses(obo:CL_0002602 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004715)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002602 obo:CL_0002320)

# Class: obo:CL_0002603 (astrocyte of the cerebellum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002603 "An astrocyte of the cerebellum.")
AnnotationAssertion(terms:contributor obo:CL_0002603 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002603 "2011-03-06T06:57:27Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002603 "astrocyte of the cerebellum")
EquivalentClasses(obo:CL_0002603 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002037)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002603 obo:CL_0000127)

# Class: obo:CL_0002604 (hippocampal astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7258-9596") obo:IAO_0000115 obo:CL_0002604 "An astrocyte that is part of the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_0002604 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002604 "2011-03-06T06:57:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002604 "astrocyte of the hippocampal formation")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002604 "astrocyte of the hippocampus")
AnnotationAssertion(rdfs:label obo:CL_0002604 "hippocampal astrocyte")
EquivalentClasses(obo:CL_0002604 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002421)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002604 obo:CL_0000127)

# Class: obo:CL_0002605 (astrocyte of the cerebral cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002605 "A transcriptomically distinct astrocyte that is found in the cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_0002605 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002605 "2011-03-06T06:57:36Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002605 "astrocyte of the cerebral cortex")
EquivalentClasses(obo:CL_0002605 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000956)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002605 obo:CL_0000127)

# Class: obo:CL_0002606 (astrocyte of the spinal cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002606 "An astrocyte of the spinal cord.")
AnnotationAssertion(terms:contributor obo:CL_0002606 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002606 "2011-03-06T07:11:26Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002606 "astrocyte of the spinal cord")
EquivalentClasses(obo:CL_0002606 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002240)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002606 obo:CL_0000127)

# Class: obo:CL_0002607 (migratory enteric neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002607 "A neural crest cell that gives rise to cells of the enteric nervous system.")
AnnotationAssertion(terms:contributor obo:CL_0002607 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002607 "2011-03-06T07:24:35Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002607 "migratory enteric neural crest cell")
SubClassOf(obo:CL_0002607 obo:CL_0000333)

# Class: obo:CL_0002608 (hippocampal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002608 "A neuron with a soma found in the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_0002608 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002608 "2011-03-06T07:31:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002608 "hippocampal neuron")
EquivalentClasses(obo:CL_0002608 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002421)))

# Class: obo:CL_0002609 (obsolete neuron of cerebral cortex)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002609 "OBSOLETE. A CNS neuron of the cerebral cortex.")
AnnotationAssertion(obo:IAO_0000231 obo:CL_0002609 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0002609 obo:CL_0010012)
AnnotationAssertion(terms:contributor obo:CL_0002609 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002609 "2011-03-06T07:37:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002609 "BTO:0004102")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002609 "FMA:84104")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002609 "cortical neuron")
AnnotationAssertion(rdfs:label obo:CL_0002609 "obsolete neuron of cerebral cortex")
AnnotationAssertion(owl:deprecated obo:CL_0002609 "true"^^xsd:boolean)

# Class: obo:CL_0002610 (raphe nuclei neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002610 "A neuron of the raphe nuclei.")
AnnotationAssertion(terms:contributor obo:CL_0002610 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002610 "2011-03-06T07:42:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002610 "raphe nuclei neuron")
EquivalentClasses(obo:CL_0002610 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0004684)))

# Class: obo:CL_0002611 (neuron of the dorsal spinal cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002611 "A CNS neuron of the dorsal spinal cord.")
AnnotationAssertion(terms:contributor obo:CL_0002611 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002611 "2011-03-06T07:43:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002611 "neuron of the dorsal spinal cord")
EquivalentClasses(obo:CL_0002611 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002256)))

# Class: obo:CL_0002612 (neuron of the ventral spinal cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002612 "A neuron of the ventral spinal cord.")
AnnotationAssertion(terms:contributor obo:CL_0002612 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002612 "2011-03-06T07:46:03Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002612 "neuron of the ventral spinal cord")
EquivalentClasses(obo:CL_0002612 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002257)))

# Class: obo:CL_0002613 (striatum neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002613 "A neuron of the striatum.")
AnnotationAssertion(terms:contributor obo:CL_0002613 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002613 "2011-03-06T07:47:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002613 "striatum neuron")
EquivalentClasses(obo:CL_0002613 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435)))

# Class: obo:CL_0002614 (neuron of the substantia nigra)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002614 "A neuron of the substantia nigra.")
AnnotationAssertion(terms:contributor obo:CL_0002614 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002614 "2011-03-06T07:48:42Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002614 "neuron of the substantia nigra")
EquivalentClasses(obo:CL_0002614 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002038)))

# Class: obo:CL_0002615 (adipocyte of omentum tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002615 "An adipocyte that is part of omentum tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002615 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002615 "2011-03-14T10:17:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002615 "omental adipocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002615 "omental fat cell")
AnnotationAssertion(rdfs:label obo:CL_0002615 "adipocyte of omentum tissue")
EquivalentClasses(obo:CL_0002615 ObjectIntersectionOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003688)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002615 obo:CL_0000136)

# Class: obo:CL_0002616 (perirenal adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002616 "An adipocyte of perirenal fat tissue.")
AnnotationAssertion(terms:contributor obo:CL_0002616 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002616 "2011-03-14T10:17:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002616 "perirenal adipocyte cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002616 "perirenal fat cell")
AnnotationAssertion(rdfs:label obo:CL_0002616 "perirenal adipocyte")
EquivalentClasses(obo:CL_0002616 ObjectIntersectionOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005406)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002616 obo:CL_0000136)

# Class: obo:CL_0002617 (adipocyte of breast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002617 "An adipocyte that is part of the breast.")
AnnotationAssertion(terms:contributor obo:CL_0002617 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002617 "2011-03-14T10:17:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002617 "CALOHA:TS-2377")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002617 "breast adipocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002617 "fat cell of breast")
AnnotationAssertion(rdfs:comment obo:CL_0002617 "Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA]")
AnnotationAssertion(rdfs:label obo:CL_0002617 "adipocyte of breast")
EquivalentClasses(obo:CL_0002617 ObjectIntersectionOf(obo:CL_0000136 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000310)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002617 obo:CL_0000136)

# Class: obo:CL_0002618 (endothelial cell of umbilical vein)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002618 "An endothelial cell of the umbilical vein.")
AnnotationAssertion(terms:contributor obo:CL_0002618 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002618 "2011-03-14T11:36:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002618 "BTO:0004296")
AnnotationAssertion(rdfs:label obo:CL_0002618 "endothelial cell of umbilical vein")
EquivalentClasses(obo:CL_0002618 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002066)))
SubClassOf(obo:CL_0002618 obo:CL_0002543)

# Class: obo:CL_0002619 (adult endothelial progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20807818") Annotation(oboInOwl:hasDbXref "PMID:9020076") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Endothelial_progenitor_cell&oldid=1069930016") obo:IAO_0000115 obo:CL_0002619 "An adult angioblastic cell released from the bone marrow, or from the kidney in some teleost species, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_0002619 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002619 "2011-03-14T12:11:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002619 "EPC")
AnnotationAssertion(rdfs:comment obo:CL_0002619 "The existence of adult endothelial progenitor cells has been controversial in the past.")
AnnotationAssertion(rdfs:label obo:CL_0002619 "adult endothelial progenitor cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0002619 "https://github.com/obophenotype/cell-ontology/issues/1410")
AnnotationAssertion(rdfs:seeAlso obo:CL_0002619 "https://github.com/obophenotype/cell-ontology/issues/348")
SubClassOf(obo:CL_0002619 obo:CL_0000566)

# Class: obo:CL_0002620 (skin fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002620 "A fibroblast of skin.")
AnnotationAssertion(terms:contributor obo:CL_0002620 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002620 "2011-03-14T12:31:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002620 "BTO:0001255")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002620 "CALOHA:TS-0935")
AnnotationAssertion(rdfs:label obo:CL_0002620 "skin fibroblast")
EquivalentClasses(obo:CL_0002620 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002097)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002620 obo:CL_0000057)

# Class: obo:CL_0002621 (gingival epithelial cell)

AnnotationAssertion(terms:contributor obo:CL_0002621 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002621 "2011-03-14T12:46:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002621 "gingival epithelial cell")
EquivalentClasses(obo:CL_0002621 ObjectIntersectionOf(obo:CL_0000240 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001949)))

# Class: obo:CL_0002622 (prostate stromal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002622 "A stromal cell of the prostate.")
AnnotationAssertion(terms:contributor obo:CL_0002622 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002622 "2011-03-14T02:11:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002622 "BTO:0003972")
AnnotationAssertion(rdfs:label obo:CL_0002622 "prostate stromal cell")
EquivalentClasses(obo:CL_0002622 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002622 obo:CL_0000499)

# Class: obo:CL_0002623 (acinar cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:24646566") Annotation(oboInOwl:hasDbXref "PMID:25843887") Annotation(oboInOwl:hasDbXref "PMID:28623666") Annotation(oboInOwl:hasDbXref "PMID:34989394") Annotation(oboInOwl:hasDbXref "PMID:35343828") obo:IAO_0000115 obo:CL_0002623 "An acinar cell that is part of the salivary gland epithelium, responsible for synthesizing and secreting the primary saliva essential for oral digestion, antimicrobial defense, and mucosal immunity. It features apical-basal polarity with apical secretory granules, and tight junctions that maintain polarity and regulate calcium-dependent saliva exocytosis triggered by parasympathetic and sympathetic signals (Ambudkar, 2015). This cell functions in coordination with contractile myoepithelial cells, which aid saliva flow through the ducts into the oral cavity (Khan et al., 2022). In mice and humans, acinar cell development relies on the transcription factor SOX2 (Emmerson et al., 2017), with self-renewal achieved primarily through acinar cell self-duplication and supported by progenitor populations during injury and regeneration (Aure et al., 2016).")
AnnotationAssertion(terms:contributor obo:CL_0002623 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002623 "2011-03-14T02:22:22Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24646566") oboInOwl:hasExactSynonym obo:CL_0002623 "salivary acinar cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24646566") oboInOwl:hasExactSynonym obo:CL_0002623 "salivary gland acinar cell")
AnnotationAssertion(rdfs:label obo:CL_0002623 "acinar cell of salivary gland")
EquivalentClasses(obo:CL_0002623 ObjectIntersectionOf(obo:CL_0000622 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004809)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002623 obo:CL_0000622)
SubClassOf(obo:CL_0002623 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030141))
SubClassOf(obo:CL_0002623 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017156))
SubClassOf(obo:CL_0002623 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087))
SubClassOf(obo:CL_0002623 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046541))

# Class: obo:CL_0002624 (paneth cell of the appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002624 "A paneth cell of the appendix.")
AnnotationAssertion(terms:contributor obo:CL_0002624 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002624 "2011-03-15T09:38:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002624 "paneth cell of the appendix")
EquivalentClasses(obo:CL_0002624 ObjectIntersectionOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002624 obo:CL_0000510)

# Class: obo:CL_0002625 (seminiferous tubule epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002625 "A cell of the seminiferous tubule epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002625 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002625 "2011-03-15T11:59:23Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002625 "seminiferous tubule epithelial cell")
EquivalentClasses(obo:CL_0002625 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001343)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002625 obo:CL_0000077)
SubClassOf(obo:CL_0002625 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004813))

# Class: obo:CL_0002626 (immature astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") obo:IAO_0000115 obo:CL_0002626 "An immature astrocyte.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002626 "immature astrocytic glia")
AnnotationAssertion(rdfs:label obo:CL_0002626 "immature astrocyte")
SubClassOf(obo:CL_0002626 obo:CL_0000127)

# Class: obo:CL_0002627 (mature astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:12898703") Annotation(oboInOwl:hasDbXref "PMID:8734446") obo:IAO_0000115 obo:CL_0002627 "A mature astrocyte that is capable of producing cytokines.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002627 "activated astrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002627 "mature astrocytic glia")
AnnotationAssertion(rdfs:comment obo:CL_0002627 "Mature astrocytes are reportedly able to produce aspartate, ATP, BDNF, BMP-2a, BMP-3, CCL2, CCL3, CCL4, CCL5, CCL19, CCL20,CD40L, CNTF, CTGF, CXCL1, CXCL2, CXCL8, edn-1, aFGF, bFGF, G-CSF, glutamate, GM-CSF, IFN-alpha, IFN-beta, IFN-gamma, IGF-1, IL-1alpha, IL-1beta, IL-2, Il-4, IL-6, IL-10, IL-12, LIF, MIP-2, NGF, nitric oxide, NT3, taurine, TGF-beta, TNF-alpha, TNF-beta.")
AnnotationAssertion(rdfs:label obo:CL_0002627 "mature astrocyte")
SubClassOf(obo:CL_0002627 obo:CL_0000127)

# Class: obo:CL_0002628 (immature microglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:18396103") Annotation(oboInOwl:hasDbXref "PMID:19461673") obo:IAO_0000115 obo:CL_0002628 "An immature microglial cell with a ramified morphology.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002628 "immature microglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18396103") oboInOwl:hasExactSynonym obo:CL_0002628 "quiescent microglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18396103") oboInOwl:hasExactSynonym obo:CL_0002628 "resting microglia")
AnnotationAssertion(rdfs:comment obo:CL_0002628 "Immature microglia are reportedly CD34-positive, CD163-negative, MHCI-negative, MHCII-negative.")
AnnotationAssertion(rdfs:label obo:CL_0002628 "immature microglial cell")
SubClassOf(obo:CL_0002628 obo:CL_0000129)

# Class: obo:CL_0002629 (mature microglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "PMID:11517395") Annotation(oboInOwl:hasDbXref "PMID:14612429") Annotation(oboInOwl:hasDbXref "PMID:15246020") Annotation(oboInOwl:hasDbXref "PMID:16177057") Annotation(oboInOwl:hasDbXref "PMID:18396103") Annotation(oboInOwl:hasDbXref "PMID:20021364") obo:IAO_0000115 obo:CL_0002629 "A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18396103") oboInOwl:hasExactSynonym obo:CL_0002629 "activated microglia")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002629 "mature microglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18396103") oboInOwl:hasExactSynonym obo:CL_0002629 "reactive microglia")
AnnotationAssertion(rdfs:comment obo:CL_0002629 "Mature microglia are reportedly CCR2-positive, CD4-positive, CD9-positive, CD11a-positive, CD11b-positive, CD11c-positive, CD13-positive, CD16-positive, CDw17-positive, CD18-positive, CD21-positive, CD26-negative, CD32-positive, CD35-positive, CD36-positive, CD40-positive, CD44-positive, CD45-positive, CD53-positive, CD54-positive, CD56-negative, CD58-positive, CD63-positive, CD64-positive, CD66-positive, CD80-positive, CD86-positive, CD87-positive, CD92-positive, CD106-positive, CD107a-positive, CD147-positive, CD155-positive, CD162-positive, CD163-positive, CD171-negative, CD200R-positive, CXCR3-positive, CX3CR1-positive, fibronectin-positive, GD3-positive, GLUT1-positive, GLUT3-negative, GLUT5-positive, MHCI-positive, MHCII-positive, P2X4-positive, RFD7-negative, RGS5-negative, alpha-SMA-negative, vimentin-positive, and vwf-negative. Mature microglia are capable of producing BDNF, CCL3, CCL5, CCL7, CCL8, CCL9, CCL19, CCL20,CD40L, CSF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, glutamate, IL-1beta, IL-1ra, IL-3, IL-6, IL-10, IL-12, LT, MMP-2, MMP-9, NGF, nitric oxide, ROS, TGF-beta, TNF-alpha.")
AnnotationAssertion(rdfs:label obo:CL_0002629 "mature microglial cell")
EquivalentClasses(obo:CL_0002629 ObjectIntersectionOf(obo:CL_0000129 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002536) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002537) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002629 obo:CL_0000129)

# Class: obo:CL_0002630 (actinomycete-type spore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0034304") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002630 "A spore formed from bacteria in the order Actinomycetales.")
AnnotationAssertion(terms:contributor obo:CL_0002630 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002630 "2011-06-16T01:01:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002630 "actinomycete-type spore")
SubClassOf(obo:CL_0002630 obo:CL_0000520)

# Class: obo:CL_0002631 (epithelial cell of upper respiratory tract)

AnnotationAssertion(terms:contributor obo:CL_0002631 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002631 "2011-06-21T12:28:55Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002631 "epithelial cell of upper respiratory tract")
EquivalentClasses(obo:CL_0002631 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004814)))

# Class: obo:CL_0002632 (epithelial cell of lower respiratory tract)

AnnotationAssertion(terms:contributor obo:CL_0002632 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002632 "2011-06-21T12:29:31Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002632 "epithelial cell of lower respiratory tract")
EquivalentClasses(obo:CL_0002632 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004815)))

# Class: obo:CL_0002633 (respiratory basal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20699479") obo:IAO_0000115 obo:CL_0002633 "A basal cell in the respiratory tract.")
AnnotationAssertion(terms:contributor obo:CL_0002633 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002633 "2011-06-21T03:11:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002633 "airway basal cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002633 "airway basal stem cell")
AnnotationAssertion(rdfs:label obo:CL_0002633 "respiratory basal cell")
EquivalentClasses(obo:CL_0002633 ObjectIntersectionOf(obo:CL_0000646 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802)))

# Class: obo:CL_0002634 (epithelial cell of anal column)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002634 "An epithelial cell of the anal column.")
AnnotationAssertion(terms:contributor obo:CL_0002634 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002634 "2011-07-08T12:11:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002634 "epithelial cell of anal column")
EquivalentClasses(obo:CL_0002634 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009882)))
SubClassOf(obo:CL_0002634 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_0002635 (nonkeratinized epithelial cell of anal column)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002635 "A nonkeratinized epithelial cell of the anal canal.")
AnnotationAssertion(terms:contributor obo:CL_0002635 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002635 "2011-07-08T02:05:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002635 "FMA:263146")
AnnotationAssertion(rdfs:label obo:CL_0002635 "nonkeratinized epithelial cell of anal column")
SubClassOf(obo:CL_0002635 obo:CL_0002634)

# Class: obo:CL_0002636 (nonkeratinized epithelial cell of inferior part of anal canal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002636 "A nonkeratinized cell epithleial cell of the inferior part of the anal canal.")
AnnotationAssertion(terms:contributor obo:CL_0002636 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002636 "2011-07-08T02:06:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002636 "FMA:263144")
AnnotationAssertion(rdfs:label obo:CL_0002636 "nonkeratinized epithelial cell of inferior part of anal canal")
SubClassOf(obo:CL_0002636 obo:CL_0002635)
SubClassOf(obo:CL_0002636 obo:CL_1000438)

# Class: obo:CL_0002637 (keratinized epithelial cell of the anal canal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002637 "An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal.")
AnnotationAssertion(terms:contributor obo:CL_0002637 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002637 "2011-07-08T02:08:40Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002637 "keratinized epithelial cell of the anal canal")
EquivalentClasses(obo:CL_0002637 ObjectIntersectionOf(obo:CL_0000237 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000159)))
SubClassOf(obo:CL_0002637 obo:CL_0000237)
SubClassOf(obo:CL_0002637 obo:CL_0002634)

# Class: obo:CL_0002638 (bronchioalveolar stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "MP:0011691") Annotation(oboInOwl:hasDbXref "PMID:15960971") obo:IAO_0000115 obo:CL_0002638 "A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and club cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc.")
AnnotationAssertion(terms:contributor obo:CL_0002638 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_0002638 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002638 "2011-06-21T03:26:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002638 "BASC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002638 "basal epithelial cell of bronchioalveolar duct junction")
AnnotationAssertion(rdfs:label obo:CL_0002638 "bronchioalveolar stem cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002638 obo:CL_0002633)
SubClassOf(obo:CL_0002638 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002051))
SubClassOf(obo:CL_0002638 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004903))

# Class: obo:CL_0002639 (amniotic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20942606") obo:IAO_0000115 obo:CL_0002639 "An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone")
AnnotationAssertion(terms:contributor obo:CL_0002639 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002639 "2011-06-21T03:55:39Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002639 "Not clear to me if amniotic stem cell is a different cell type from amnion mesenchymal stem cells. They are treated as distinct in the literature as isolations methods are different, so I will keep them as separate terms for now.")
AnnotationAssertion(rdfs:label obo:CL_0002639 "amniotic stem cell")
SubClassOf(obo:CL_0002639 obo:CL_0000134)
SubClassOf(obo:CL_0002639 obo:CL_0002323)

# Class: obo:CL_0002640 (amniotic epithelial stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20446274") obo:IAO_0000115 obo:CL_0002640 "An epithelial fate stem cell derived form the amnion membrane.")
AnnotationAssertion(terms:contributor obo:CL_0002640 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002640 "2011-06-21T04:06:17Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002640 "amniotic epithelial stem cell")
SubClassOf(obo:CL_0002640 obo:CL_0000036)

# Class: obo:CL_0002641 (epithelial cell of esophageal gland proper)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002641 "An epithelial cell of the esophageal gland proper.")
AnnotationAssertion(terms:contributor obo:CL_0002641 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002641 "2011-07-08T02:16:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002641 "FMA:256141")
AnnotationAssertion(rdfs:label obo:CL_0002641 "epithelial cell of esophageal gland proper")
SubClassOf(obo:CL_0002641 obo:CL_0002657)
SubClassOf(obo:CL_0002641 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976))

# Class: obo:CL_0002642 (epithelial cell of esophageal cardiac gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "http://web.mac.com/wjkrause/iWeb/Histology/Blog/E3FA5916-1AA9-4885-B579-5051838D98CB.html") obo:IAO_0000115 obo:CL_0002642 "An epithelial cell of the esophageal cardiac gland that occurs both in the proximal and distal esophagus, within the lamina propia.")
AnnotationAssertion(terms:contributor obo:CL_0002642 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002642 "2011-07-08T02:16:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002642 "FMA:256143")
AnnotationAssertion(rdfs:label obo:CL_0002642 "epithelial cell of esophageal cardiac gland")
SubClassOf(obo:CL_0002642 obo:CL_0002657)
SubClassOf(obo:CL_0002642 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976))

# Class: obo:CL_0002643 (nonkeratinized cell of stratum corneum of esophageal epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002643 "An epithelial cell of stratum corneum of esophageal epithelium that lacks keratin.")
AnnotationAssertion(terms:contributor obo:CL_0002643 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002643 "2011-07-08T02:22:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002643 "FMA:263148")
AnnotationAssertion(rdfs:label obo:CL_0002643 "nonkeratinized cell of stratum corneum of esophageal epithelium")
SubClassOf(obo:CL_0002643 obo:CL_0002654)
SubClassOf(obo:CL_0002643 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976))

# Class: obo:CL_0002644 (endo-epithelial cell of tympanic part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002644 "An endothelial cell of viscerocranial mucosa that is part of the tympanic region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002644 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002644 "2011-07-08T02:25:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002644 "FMA:70628")
AnnotationAssertion(rdfs:label obo:CL_0002644 "endo-epithelial cell of tympanic part of viscerocranial mucosa")
SubClassOf(obo:CL_0002644 obo:CL_0002261)

# Class: obo:CL_0002645 (endo-epithelial cell of pharyngotympanic part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002645 "An endocranial viscerocranial mucosa cell that is part of viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002645 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002645 "2011-07-08T02:25:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002645 "FMA:70629")
AnnotationAssertion(rdfs:label obo:CL_0002645 "endo-epithelial cell of pharyngotympanic part of viscerocranial mucosa")
SubClassOf(obo:CL_0002645 obo:CL_0002261)

# Class: obo:CL_0002646 (obsolete epithelial cell of buccal part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002646 "An ecto-epithelial cell of the buccal region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002646 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002646 "2011-07-08T02:34:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002646 "FMA:70577")
AnnotationAssertion(rdfs:label obo:CL_0002646 "obsolete epithelial cell of buccal part of viscerocranial mucosa")
AnnotationAssertion(owl:deprecated obo:CL_0002646 "true"^^xsd:boolean)

# Class: obo:CL_0002647 (obsolete epithelial cell of anterior palatal part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002647 "An ecto-epithelial cell of the palatal region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002647 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002647 "2011-07-08T02:34:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002647 "FMA:70580")
AnnotationAssertion(rdfs:label obo:CL_0002647 "obsolete epithelial cell of anterior palatal part of viscerocranial mucosa")
AnnotationAssertion(owl:deprecated obo:CL_0002647 "true"^^xsd:boolean)

# Class: obo:CL_0002648 (obsolete epithelial cell of nasal part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002648 "An ecto-epithelial cell of the nasal region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002648 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002648 "2011-07-08T02:36:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002648 "FMA:70554")
AnnotationAssertion(rdfs:label obo:CL_0002648 "obsolete epithelial cell of nasal part of viscerocranial mucosa")
AnnotationAssertion(owl:deprecated obo:CL_0002648 "true"^^xsd:boolean)

# Class: obo:CL_0002649 (obsolete epithelial cell of gingival part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002649 "An ecto-epithelial cell of the gingival region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002649 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002649 "2011-07-08T02:36:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002649 "FMA:70579")
AnnotationAssertion(rdfs:label obo:CL_0002649 "obsolete epithelial cell of gingival part of viscerocranial mucosa")
AnnotationAssertion(owl:deprecated obo:CL_0002649 "true"^^xsd:boolean)

# Class: obo:CL_0002650 (obsolete epithelial cell of paranasal sinus part of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002650 "An ecto-epithelial cell of the paranasal region of the viscerocranial mucosa.")
AnnotationAssertion(terms:contributor obo:CL_0002650 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002650 "2011-07-08T02:38:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002650 "FMA:70578")
AnnotationAssertion(rdfs:label obo:CL_0002650 "obsolete epithelial cell of paranasal sinus part of viscerocranial mucosa")
AnnotationAssertion(owl:deprecated obo:CL_0002650 "true"^^xsd:boolean)

# Class: obo:CL_0002651 (endothelial cell of venous sinus of spleen)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002651 "An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits.")
AnnotationAssertion(terms:contributor obo:CL_0002651 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002651 "2011-07-08T03:06:49Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002651 "FMA:72140")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:62817") oboInOwl:hasExactSynonym obo:CL_0002651 "stave cell")
AnnotationAssertion(rdfs:label obo:CL_0002651 "endothelial cell of venous sinus of spleen")
SubClassOf(obo:CL_0002651 obo:CL_0002262)

# Class: obo:CL_0002652 (endothelial cell of high endothelial venule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20726857") obo:IAO_0000115 obo:CL_0002652 "A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.")
AnnotationAssertion(terms:contributor obo:CL_0002652 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002652 "2011-07-08T03:14:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002652 "endothelial cell of postcapillary venule of lymph node")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002652 "FMA:67759")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002652 "HEV cell")
AnnotationAssertion(rdfs:comment obo:CL_0002652 "Markers expressed on HEV include: MAdCAM-1,PNAd (sulfated and glycosylated molecules, i.e. GlyCAM-1, CD34, endomucin, nepmucin), ICAM-1, ICAM-2,Fuc-TVII, beta 3GlcNAcT-3, GlcNAc6ST2,CCL21, CCL19, CXCL13, CXCL12, Autotaxin, DARC, angiomodulin, LRHG.")
AnnotationAssertion(rdfs:label obo:CL_0002652 "endothelial cell of high endothelial venule")
EquivalentClasses(obo:CL_0002652 ObjectIntersectionOf(obo:CL_0002139 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410037)))

# Class: obo:CL_0002653 (squamous endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0002653 "A squamous shaped endothelial cell.")
AnnotationAssertion(terms:contributor obo:CL_0002653 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002653 "2011-07-08T03:31:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002653 "squamous endothelial cell")
SubClassOf(obo:CL_0002653 obo:CL_0000115)

# Class: obo:CL_0002654 (epithelial cell of stratum corneum of esophageal epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002654 "An epithelial cell of stratum corneum of esophageal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002654 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002654 "2011-07-08T03:46:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002654 "FMA:70733")
AnnotationAssertion(rdfs:label obo:CL_0002654 "epithelial cell of stratum corneum of esophageal epithelium")
SubClassOf(obo:CL_0002654 obo:CL_0002252)

# Class: obo:CL_0002655 (epithelial cell of stratum spinosum of esophageal epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002655 "An epithelial cell of stratum spinosum of esophageal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0002655 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002655 "2011-07-08T03:48:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002655 "FMA:70732")
AnnotationAssertion(rdfs:label obo:CL_0002655 "epithelial cell of stratum spinosum of esophageal epithelium")
SubClassOf(obo:CL_0002655 obo:CL_0002252)

# Class: obo:CL_0002656 (glandular endometrial unciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:25023676") obo:IAO_0000115 obo:CL_0002656 "A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs.")
AnnotationAssertion(terms:contributor obo:CL_0002656 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002656 "2011-07-08T03:54:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002656 "glandular cell of endometrium")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002656 "FMA:86489")
AnnotationAssertion(rdfs:label obo:CL_0002656 "glandular endometrial unciliated epithelial cell")
EquivalentClasses(obo:CL_0002656 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002451) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940)))

# Class: obo:CL_0002657 (glandular cell of esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002657 "A glandular epithelial cell of the esophagus.")
AnnotationAssertion(terms:contributor obo:CL_0002657 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002657 "2011-07-08T03:55:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002657 "FMA:86548")
AnnotationAssertion(rdfs:label obo:CL_0002657 "glandular cell of esophagus")
EquivalentClasses(obo:CL_0002657 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002657 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002657 obo:CL_0002252)

# Class: obo:CL_0002658 (glandular cell of the large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002658 "A glandular epithelial cell of the large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002658 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002658 "2011-07-08T04:03:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002658 "FMA:87194")
AnnotationAssertion(rdfs:label obo:CL_0002658 "glandular cell of the large intestine")
EquivalentClasses(obo:CL_0002658 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000059)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002658 obo:CL_0000150)
SubClassOf(obo:CL_0002658 obo:CL_0002253)

# Class: obo:CL_0002659 (glandular epithelial cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002659 "A glandular epithelial cell that is part of the stomach.")
AnnotationAssertion(terms:contributor obo:CL_0002659 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002659 "2011-07-11T01:20:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002659 "CALOHA:TS-1284")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002659 "FMA:86554")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002659 "glandular cell of stomach")
AnnotationAssertion(rdfs:label obo:CL_0002659 "glandular epithelial cell of stomach")
EquivalentClasses(obo:CL_0002659 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))

# Class: obo:CL_0002660 (luminal cell of acinus of lactiferous gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002660 "A luminal epithelial cell of mammary gland located in acinus of structure.")
AnnotationAssertion(terms:contributor obo:CL_0002660 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002660 "2011-07-11T01:44:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002660 "FMA:74505")
AnnotationAssertion(rdfs:comment obo:CL_0002660 "Consider if synonymous with mammary alveolar cell CL:0002325. Some use this term to refer to the non-lactating cell type that gives rise to the lactating cell type.")
AnnotationAssertion(rdfs:label obo:CL_0002660 "luminal cell of acinus of lactiferous gland")
SubClassOf(obo:CL_0002660 obo:CL_0002326)

# Class: obo:CL_0002661 (luminal cell of lactiferous terminal ductal lobular unit)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002661 "A luminal cell of terminal ducts, i.e.e the terminal branch of a lactiferous duct which alveolar cells drain into.")
AnnotationAssertion(terms:contributor obo:CL_0002661 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002661 "2011-07-11T01:44:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002661 "FMA:87168")
AnnotationAssertion(rdfs:label obo:CL_0002661 "luminal cell of lactiferous terminal ductal lobular unit")
SubClassOf(obo:CL_0002661 obo:CL_0002662)

# Class: obo:CL_0002662 (luminal cell of lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19022771") obo:IAO_0000115 obo:CL_0002662 "A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive.")
AnnotationAssertion(terms:contributor obo:CL_0002662 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002662 "2011-07-11T01:44:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002662 "FMA:74504")
AnnotationAssertion(rdfs:label obo:CL_0002662 "luminal cell of lactiferous duct")
SubClassOf(obo:CL_0002662 obo:CL_0002326)

# Class: obo:CL_0002663 (myocardial endocrine cell of atrium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002663 "A myocardial endocrine cell that is part of the atrium.")
AnnotationAssertion(terms:contributor obo:CL_0002663 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002663 "2011-07-11T02:45:39Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002663 "FMA:83389")
AnnotationAssertion(rdfs:label obo:CL_0002663 "myocardial endocrine cell of atrium")
EquivalentClasses(obo:CL_0002663 ObjectIntersectionOf(obo:CL_0002074 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002081)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002663 obo:CL_0002074)

# Class: obo:CL_0002664 (cardioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19745164") obo:IAO_0000115 obo:CL_0002664 "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart.")
AnnotationAssertion(terms:contributor obo:CL_0002664 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002664 "2011-07-11T03:15:38Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17519333") Annotation(oboInOwl:hasDbXref "PMID:19745164") oboInOwl:hasExactSynonym obo:CL_0002664 "cardiovascular progenitor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19745164") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0002664 "CPC")
AnnotationAssertion(rdfs:comment obo:CL_0002664 "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.")
AnnotationAssertion(rdfs:label obo:CL_0002664 "cardioblast")
SubClassOf(obo:CL_0002664 obo:CL_0000048)

# Class: obo:CL_0002665 (otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") Annotation(oboInOwl:hasDbXref "PMID:37720106") obo:IAO_0000115 obo:CL_0002665 "A mesenchymal cell within the inner ear, specifically localised to supportive connective tissues such as the spiral ligament and spiral limbus. This cell has specialised structural and molecular adaptations, and it contributes to the homeostasis of the cochlear environment by participating in ionic regulation crucial for auditory function.")
AnnotationAssertion(terms:contributor obo:CL_0002665 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002665 "2011-07-11T03:35:01Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34436572") oboInOwl:hasNarrowSynonym obo:CL_0002665 "cochlear fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002665 "otic fibrocyte")
SubClassOf(obo:CL_0002665 obo:CL_0008019)
SubClassOf(obo:CL_0002665 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001846))

# Class: obo:CL_0002666 (type 2 otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") obo:IAO_0000115 obo:CL_0002666 "An otic fibrocyte that underlies the spiral prominence and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph.")
AnnotationAssertion(terms:contributor obo:CL_0002666 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002666 "2011-07-11T03:40:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002666 "type II otic fibrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004488") oboInOwl:hasExactSynonym obo:CL_0002666 "type II spiral ligament fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002666 "type 2 otic fibrocyte")
SubClassOf(obo:CL_0002666 obo:CL_0002665)

# Class: obo:CL_0002667 (type 5 otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") obo:IAO_0000115 obo:CL_0002667 "An otic fibrocyte that resides above the stria vasularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph.")
AnnotationAssertion(terms:contributor obo:CL_0002667 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002667 "2011-07-11T03:40:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002667 "type V otic fibrocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002667 "type V spiral ligament fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002667 "type 5 otic fibrocyte")
SubClassOf(obo:CL_0002667 obo:CL_0002665)

# Class: obo:CL_0002668 (type 4 otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") obo:IAO_0000115 obo:CL_0002668 "An otic fibrocyte that is lateral to the basilar membrane and anchoris it to the lateral wall.")
AnnotationAssertion(terms:contributor obo:CL_0002668 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002668 "2011-07-11T03:40:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002668 "type IV otic fibrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004490") oboInOwl:hasExactSynonym obo:CL_0002668 "type IV spiral ligament fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002668 "type 4 otic fibrocyte")
SubClassOf(obo:CL_0002668 obo:CL_0002665)

# Class: obo:CL_0002669 (type 3 otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") obo:IAO_0000115 obo:CL_0002669 "An otic fibrocyte that lines the otic capsule.")
AnnotationAssertion(terms:contributor obo:CL_0002669 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002669 "2011-07-11T03:40:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002669 "type III otic fibrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004489") oboInOwl:hasExactSynonym obo:CL_0002669 "type III spiral ligament fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002669 "type 3 otic fibrocyte")
SubClassOf(obo:CL_0002669 obo:CL_0002665)

# Class: obo:CL_0002670 (type 1 otic fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18353863") obo:IAO_0000115 obo:CL_0002670 "An otic fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph.")
AnnotationAssertion(terms:contributor obo:CL_0002670 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002670 "2011-07-11T03:39:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002670 "type I otic fibrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004487") oboInOwl:hasExactSynonym obo:CL_0002670 "type I spiral ligament fibrocyte")
AnnotationAssertion(rdfs:label obo:CL_0002670 "type 1 otic fibrocyte")
SubClassOf(obo:CL_0002670 obo:CL_0002665)

# Class: obo:CL_0002671 (endothelial stalk cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:21521739") obo:IAO_0000115 obo:CL_0002671 "An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout.")
AnnotationAssertion(terms:contributor obo:CL_0002671 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002671 "2011-08-16T01:49:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002671 "endothelial stalk cell")
SubClassOf(obo:CL_0002671 obo:CL_0000071)

# Class: obo:CL_0002672 (retinal progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20959166") Annotation(oboInOwl:hasDbXref "PMID:21148186") obo:IAO_0000115 obo:CL_0002672 "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells.")
AnnotationAssertion(terms:contributor obo:CL_0002672 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002672 "2011-08-16T02:38:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002672 "retinal progenitor cell")
SubClassOf(obo:CL_0002672 obo:CL_0000048)
SubClassOf(obo:CL_0002672 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0002673 (tongue muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:18816858") obo:IAO_0000115 obo:CL_0002673 "A skeletal muscle cell that is part of the tongue.")
AnnotationAssertion(terms:contributor obo:CL_0002673 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002673 "2011-08-16T03:10:02Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002673 "tongue muscle cell")
EquivalentClasses(obo:CL_0002673 ObjectIntersectionOf(obo:CL_0008002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000378)))

# Class: obo:CL_0002674 (H minus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002674 "A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus.")
AnnotationAssertion(terms:contributor obo:CL_0002674 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002674 "2011-08-16T03:20:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002674 "H- cell")
AnnotationAssertion(rdfs:label obo:CL_0002674 "H minus")
SubClassOf(obo:CL_0002674 obo:CL_0000521)
SubClassOf(obo:CL_0002674 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_4896))

# Class: obo:CL_0002675 (H plus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002675 "A S. pombe cell type determined by mat1-Pc and mat1-Pi on the mat1 locus.")
AnnotationAssertion(terms:contributor obo:CL_0002675 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002675 "2011-08-16T03:20:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002675 "H plus")
SubClassOf(obo:CL_0002675 obo:CL_0000521)
SubClassOf(obo:CL_0002675 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_4896))

# Class: obo:CL_0002676 (neural crest derived neuroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:17407019") obo:IAO_0000115 obo:CL_0002676 "A neuroblast derived from a neural crest cell.")
AnnotationAssertion(terms:contributor obo:CL_0002676 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002676 "2011-08-22T09:24:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002676 "neural crest derived neuroblast")
SubClassOf(obo:CL_0002676 obo:CL_0000031)
SubClassOf(obo:CL_0002676 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0002677 (naive regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002677 "A regulatory T cell that has not encountered antigen.")
AnnotationAssertion(terms:contributor obo:CL_0002677 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002677 "2011-08-25T03:17:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002677 "naive regulatory T lymphocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002677 "naive regulatory T-cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002677 "naive regulatory T-lymphocyte")
AnnotationAssertion(rdfs:comment obo:CL_0002677 "This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell.")
AnnotationAssertion(rdfs:label obo:CL_0002677 "naive regulatory T cell")
SubClassOf(obo:CL_0002677 obo:CL_0000792)
SubClassOf(obo:CL_0002677 obo:CL_0000898)

# Class: obo:CL_0002678 (memory regulatory T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:21739668") obo:IAO_0000115 obo:CL_0002678 "A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen.")
AnnotationAssertion(terms:contributor obo:CL_0002678 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002678 "2011-08-25T03:17:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0002678 "Cell has been described as being CD45RA-positive in human, but this doesn't fit with our current definition memory T cell.")
AnnotationAssertion(rdfs:label obo:CL_0002678 "memory regulatory T cell")
EquivalentClasses(obo:CL_0002678 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379)))
SubClassOf(obo:CL_0002678 obo:CL_0000792)
SubClassOf(obo:CL_0002678 obo:CL_0000813)

# Class: obo:CL_0002679 (natural helper lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20023630") obo:IAO_0000115 obo:CL_0002679 "A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13")
AnnotationAssertion(terms:contributor obo:CL_0002679 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002679 "2011-08-29T10:08:02Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002679 "natural helper lymphocyte")
EquivalentClasses(obo:CL_0002679 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042105) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002679 obo:CL_0000542)

# Class: obo:CL_0002680 (PP cell of intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:2420136") Annotation(oboInOwl:hasDbXref "PMID:728970") obo:IAO_0000115 obo:CL_0002680 "A PP cell found in intestine.")
AnnotationAssertion(terms:contributor obo:CL_0002680 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002680 "2011-09-27T11:59:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002680 "PP cell of intestine")
EquivalentClasses(obo:CL_0002680 ObjectIntersectionOf(obo:CL_0000696 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002680 obo:CL_0000696)

# Class: obo:CL_0002681 (kidney cortical cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0002681 "A cell that is part of a cortex of kidney.")
AnnotationAssertion(terms:contributor obo:CL_0002681 <https://orcid.org/0000-0002-0956-8634>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002681 "2011-10-25T03:49:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0002681 "kidney cortical cell")
EquivalentClasses(obo:CL_0002681 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001225)))

# Class: obo:CL_0003001 (bistratified retinal ganglion cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0003001 "A retinal ganglion cell that has dendrites stratified in two layers of the inner-plexiform layer.")
AnnotationAssertion(terms:contributor obo:CL_0003001 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003001 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0003001 "retinal ganglion D cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003001 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003001 "CL:0003001")
AnnotationAssertion(rdfs:label obo:CL_0003001 "bistratified retinal ganglion cell")
EquivalentClasses(obo:CL_0003001 ObjectIntersectionOf(obo:CL_0000740 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062)))

# Class: obo:CL_0003002 (G1 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003002 "A retinal ganglion cell that has a small dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S3.")
AnnotationAssertion(terms:contributor obo:CL_0003002 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003002 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003002 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003002 "CL:0003002")
AnnotationAssertion(rdfs:label obo:CL_0003002 "G1 retinal ganglion cell")
SubClassOf(obo:CL_0003002 obo:CL_0000740)
SubClassOf(obo:CL_0003002 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003002 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003003 (G2 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003003 "A mono-stratified retinal ganglion cell that has a small dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S3.")
AnnotationAssertion(terms:contributor obo:CL_0003003 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003003 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003003 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003003 "CL:0003003")
AnnotationAssertion(rdfs:label obo:CL_0003003 "G2 retinal ganglion cell")
SubClassOf(obo:CL_0003003 obo:CL_0000740)
SubClassOf(obo:CL_0003003 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003003 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003003 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003004 (G3 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003004 "A bistratified retinal ganglion cell that has a small dendritic field with sparse density that terminates at the intersection of the S4-S5 sublaminar level, and a second dendrite field that is medium in size and degree of arborization that terminates in sublaminar layer S2.")
AnnotationAssertion(terms:contributor obo:CL_0003004 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003004 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003004 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003004 "CL:0003004")
AnnotationAssertion(rdfs:comment obo:CL_0003004 "is_a bistratified retinal ganglion cell S4-S5 dendrite field having (small dendritic field, sparse density) and second dendrite field having (medium, meduim)")
AnnotationAssertion(rdfs:label obo:CL_0003004 "G3 retinal ganglion cell")
SubClassOf(obo:CL_0003004 obo:CL_0000740)
SubClassOf(obo:CL_0003004 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003004 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003004 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003004 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))
SubClassOf(obo:CL_0003004 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009851))

# Class: obo:CL_0003005 (G4 retinal ganglion cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0003005 "A mono-stratified retinal ganglion cell that has a small dendritic field and dense dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0003005 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003005 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003005 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003005 "CL:0003005")
AnnotationAssertion(rdfs:comment obo:CL_0003005 "Masland nomenclature PMID:11978858")
AnnotationAssertion(rdfs:label obo:CL_0003005 "G4 retinal ganglion cell")
SubClassOf(obo:CL_0003005 obo:CL_0000740)
SubClassOf(obo:CL_0003005 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003005 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))

# Class: obo:CL_0003006 (G4-ON retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003006 "A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S3 and S4 and is depolarized by illumination of its receptive field center.")
AnnotationAssertion(terms:contributor obo:CL_0003006 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003006 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003006 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003006 "CL:0003006")
AnnotationAssertion(rdfs:label obo:CL_0003006 "G4-ON retinal ganglion cell")
SubClassOf(obo:CL_0003006 obo:CL_0003005)
SubClassOf(obo:CL_0003006 obo:CL_4023032)
SubClassOf(obo:CL_0003006 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0003006 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003007 (G4-OFF retinal ganglion cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0003007 "A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S2 and S3 and is depolarized by decreased illumination of their receptive field center")
AnnotationAssertion(terms:contributor obo:CL_0003007 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003007 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003007 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003007 "CL:0003007")
AnnotationAssertion(rdfs:comment obo:CL_0003007 "Masland nomenclature PMID:11978858")
AnnotationAssertion(rdfs:label obo:CL_0003007 "G4-OFF retinal ganglion cell")
SubClassOf(obo:CL_0003007 obo:CL_0003005)
SubClassOf(obo:CL_0003007 obo:CL_4023033)
SubClassOf(obo:CL_0003007 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003007 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003008 (G5 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003008 "A mono-stratified retinal ganglion cell that has a medium dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S2.")
AnnotationAssertion(terms:contributor obo:CL_0003008 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003008 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003008 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003008 "CL:0003008")
AnnotationAssertion(rdfs:label obo:CL_0003008 "G5 retinal ganglion cell")
SubClassOf(obo:CL_0003008 obo:CL_0000740)
SubClassOf(obo:CL_0003008 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003008 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003008 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003009 (G6 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003009 "A mono-stratified retinal ganglion cell that has a medium dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S4 and S5.")
AnnotationAssertion(terms:contributor obo:CL_0003009 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003009 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003009 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003009 "CL:0003009")
AnnotationAssertion(rdfs:label obo:CL_0003009 "G6 retinal ganglion cell")
SubClassOf(obo:CL_0003009 obo:CL_0000740)
SubClassOf(obo:CL_0003009 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003009 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003009 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))
SubClassOf(obo:CL_0003009 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008926))

# Class: obo:CL_0003010 (G7 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003010 "A bistratified retinal ganglion cell that has a dendrite field that terminates in sublaminar layer S2 and a second dendrite field that terminates in sublaminar layer S4.")
AnnotationAssertion(terms:contributor obo:CL_0003010 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003010 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0003010 "ON-OFF DS")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003010 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003010 "CL:0003010")
AnnotationAssertion(rdfs:label obo:CL_0003010 "G7 retinal ganglion cell")
SubClassOf(obo:CL_0003010 obo:CL_0000740)
SubClassOf(obo:CL_0003010 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003010 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003010 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003010 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003011 (G8 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003011 "A mono-stratified retinal ganglion cell that has a large dendritic field and a sparse dendritic arbor with post synaptic terminals in sublaminar layer S4.")
AnnotationAssertion(terms:contributor obo:CL_0003011 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003011 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003011 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003011 "CL:0003011")
AnnotationAssertion(rdfs:label obo:CL_0003011 "G8 retinal ganglion cell")
SubClassOf(obo:CL_0003011 obo:CL_0000740)
SubClassOf(obo:CL_0003011 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003011 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003011 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003012 (G9 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003012 "A mono-stratified retinal ganglion cell that has a large dendritic field and a medium dendritic arbor with post synaptic terminals in sublaminar layer S1 and S2.")
AnnotationAssertion(terms:contributor obo:CL_0003012 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003012 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003012 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003012 "CL:0003012")
AnnotationAssertion(rdfs:label obo:CL_0003012 "G9 retinal ganglion cell")
SubClassOf(obo:CL_0003012 obo:CL_0000740)
SubClassOf(obo:CL_0003012 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003012 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003012 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0003012 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003013 (G10 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003013 "A mono-stratified retinal ganglion cell that has a large dendritic field, a medium dendritic arbor, and a long secondary dendrite shaft with post synaptic terminals in sublaminar layer S4.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003013 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003013 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003013 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003013 "CL:0003013")
AnnotationAssertion(rdfs:comment obo:CL_0003013 "Capable of ON directional sensitivity.")
AnnotationAssertion(rdfs:label obo:CL_0003013 "G10 retinal ganglion cell")
SubClassOf(obo:CL_0003013 obo:CL_0000740)
SubClassOf(obo:CL_0003013 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003013 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))
SubClassOf(obo:CL_0003013 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003014 (G11 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003014 "A mono-stratified retinal ganglion cell that has a large dendritic field, a medium dendritic arbor, and a medium length secondary dendrite shaft.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003014 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003014 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003014 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003014 "CL:0003014")
AnnotationAssertion(rdfs:comment obo:CL_0003014 "Is capable of brisk transient currents.")
AnnotationAssertion(rdfs:label obo:CL_0003014 "G11 retinal ganglion cell")
SubClassOf(obo:CL_0003014 obo:CL_0000740)
SubClassOf(obo:CL_0003014 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003014 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9986))

# Class: obo:CL_0003015 (G11-ON retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003015 "A G11 retinal ganglion cell that has post synaptic terminals in sublaminar layer S4 and is depolarized by illumination of its receptive field center.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003015 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003015 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003015 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003015 "CL:0003015")
AnnotationAssertion(rdfs:label obo:CL_0003015 "G11-ON retinal ganglion cell")
SubClassOf(obo:CL_0003015 obo:CL_0003014)
SubClassOf(obo:CL_0003015 obo:CL_4023032)
SubClassOf(obo:CL_0003015 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003016 (G11-OFF retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11978858") obo:IAO_0000115 obo:CL_0003016 "A G11 retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003016 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003016 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003016 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003016 "CL:0003016")
AnnotationAssertion(rdfs:label obo:CL_0003016 "G11-OFF retinal ganglion cell")
SubClassOf(obo:CL_0003016 obo:CL_0003014)
SubClassOf(obo:CL_0003016 obo:CL_4023033)
SubClassOf(obo:CL_0003016 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003017 (retinal ganglion cell B3 outer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003017 "A retinal ganglion B cell that has post synaptic terminals in S2.")
AnnotationAssertion(terms:contributor obo:CL_0003017 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003017 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003017 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003017 "CL:0003017")
AnnotationAssertion(rdfs:label obo:CL_0003017 "retinal ganglion cell B3 outer")
SubClassOf(obo:CL_0003017 obo:CL_0004183)
SubClassOf(obo:CL_0003017 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003018 (retinal ganglion cell B3 inner)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003018 "A retinal ganglion B3 cell with dentrites terminating in S4.")
AnnotationAssertion(terms:contributor obo:CL_0003018 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003018 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0003018 "BAMS:1010")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003018 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003018 "CL:0003018")
AnnotationAssertion(rdfs:label obo:CL_0003018 "retinal ganglion cell B3 inner")
SubClassOf(obo:CL_0003018 obo:CL_0004183)
SubClassOf(obo:CL_0003018 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003020 (retinal ganglion cell C outer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003020 "A retinal ganglion cell C that has post-synaptic terminals in S2.")
AnnotationAssertion(terms:contributor obo:CL_0003020 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003020 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003020 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003020 "CL:0003020")
AnnotationAssertion(rdfs:label obo:CL_0003020 "retinal ganglion cell C outer")
SubClassOf(obo:CL_0003020 obo:CL_0004116)
SubClassOf(obo:CL_0003020 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003021 (retinal ganglion cell C4)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003021 "A retinal ganglion cell C outer that has a medium dendritic field and a dense dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0003021 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003021 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003021 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003021 "CL:0003021")
AnnotationAssertion(rdfs:label obo:CL_0003021 "retinal ganglion cell C4")
SubClassOf(obo:CL_0003021 obo:CL_0003020)

# Class: obo:CL_0003022 (retinal ganglion cell C5)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003022 "A retinal ganglion cell C outer that has medium dendritic density and field size.")
AnnotationAssertion(terms:contributor obo:CL_0003022 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003022 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003022 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003022 "CL:0003022")
AnnotationAssertion(rdfs:label obo:CL_0003022 "retinal ganglion cell C5")
SubClassOf(obo:CL_0003022 obo:CL_0003020)

# Class: obo:CL_0003023 (retinal ganglion cell C6)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003023 "A retinal ganglion cell C outer that has dense dendritic diversity.")
AnnotationAssertion(terms:contributor obo:CL_0003023 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003023 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003023 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003023 "CL:0003023")
AnnotationAssertion(rdfs:label obo:CL_0003023 "retinal ganglion cell C6")
SubClassOf(obo:CL_0003023 obo:CL_0003020)

# Class: obo:CL_0003024 (retinal ganglion cell C inner)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003024 "A retinal ganglion cell C with medium cell bodies and large dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0003024 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003024 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003024 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003024 "CL:0003024")
AnnotationAssertion(rdfs:label obo:CL_0003024 "retinal ganglion cell C inner")
SubClassOf(obo:CL_0003024 obo:CL_0004116)
SubClassOf(obo:CL_0003024 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003025 (retinal ganglion cell C3)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003025 "A retinal ganglion cell C inner that has sparse dendritic density, and large dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0003025 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003025 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003025 "cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0003025 "epsilon")
AnnotationAssertion(oboInOwl:id obo:CL_0003025 "CL:0003025")
AnnotationAssertion(rdfs:label obo:CL_0003025 "retinal ganglion cell C3")
SubClassOf(obo:CL_0003025 obo:CL_0003024)

# Class: obo:CL_0003026 (retinal ganglion cell D1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003026 "A bistratified retinal ganglion cell that has a small dendrite fields with a sparse dendrite arbor terminating in S2 and S3.")
AnnotationAssertion(terms:contributor obo:CL_0003026 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003026 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003026 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003026 "CL:0003026")
AnnotationAssertion(rdfs:label obo:CL_0003026 "retinal ganglion cell D1")
SubClassOf(obo:CL_0003026 obo:CL_0000740)
SubClassOf(obo:CL_0003026 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003026 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003026 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003026 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003027 (retinal ganglion cell D2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0003027 "A bistratified retinal ganglion cell D cell that has medium dendritic arbor and a large dendritic field that terminates in S2 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0003027 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003027 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003027 "cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0003027 "ON-OFF direction selective")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0003027 "iota cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003027 "CL:0003027")
AnnotationAssertion(rdfs:label obo:CL_0003027 "retinal ganglion cell D2")
SubClassOf(obo:CL_0003027 obo:CL_0000740)
SubClassOf(obo:CL_0003027 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003027 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003027 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003027 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003028 (M1 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003028 "A monostratified retinal ganglion cell that has a small dendrite field with a dense dendrite arbor with post synaptic terminals in sublaminer layer S4.")
AnnotationAssertion(terms:contributor obo:CL_0003028 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003028 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003028 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003028 "CL:0003028")
AnnotationAssertion(rdfs:label obo:CL_0003028 "M1 retinal ganglion cell")
SubClassOf(obo:CL_0003028 obo:CL_0000740)
SubClassOf(obo:CL_0003028 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003028 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003028 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003029 (M2 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003029 "A monostratified retinal ganglion cell that has a small soma, a small dendrite field with a dense dendrite arbor, and post synaptic terminals in sublaminer layer S2 and S3.")
AnnotationAssertion(terms:contributor obo:CL_0003029 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003029 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003029 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003029 "CL:0003029")
AnnotationAssertion(rdfs:label obo:CL_0003029 "M2 retinal ganglion cell")
SubClassOf(obo:CL_0003029 obo:CL_0000740)
SubClassOf(obo:CL_0003029 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003029 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003029 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003029 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003030 (M3 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003030 "A monostratified retinal ganglion cell that has a medium soma and a small dendrite field.")
AnnotationAssertion(terms:contributor obo:CL_0003030 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003030 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003030 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003030 "CL:0003030")
AnnotationAssertion(rdfs:label obo:CL_0003030 "M3 retinal ganglion cell")
SubClassOf(obo:CL_0003030 obo:CL_0000740)
SubClassOf(obo:CL_0003030 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003030 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0003031 (M3-ON retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003031 "A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S4 and is depolarized by illumination of its receptive field center.")
AnnotationAssertion(terms:contributor obo:CL_0003031 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003031 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003031 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003031 "CL:0003031")
AnnotationAssertion(rdfs:label obo:CL_0003031 "M3-ON retinal ganglion cell")
SubClassOf(obo:CL_0003031 obo:CL_0003030)
SubClassOf(obo:CL_0003031 obo:CL_4023032)
SubClassOf(obo:CL_0003031 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003032 (M3-OFF retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003032 "A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center")
AnnotationAssertion(terms:contributor obo:CL_0003032 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003032 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003032 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003032 "CL:0003032")
AnnotationAssertion(rdfs:label obo:CL_0003032 "M3-OFF retinal ganglion cell")
SubClassOf(obo:CL_0003032 obo:CL_0003030)
SubClassOf(obo:CL_0003032 obo:CL_4023033)
SubClassOf(obo:CL_0003032 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003033 (M4 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003033 "A monostratified retinal ganglion cell that has a large soma, a medium dendritic field with post synaptic terminals in sublaminar layer S3.")
AnnotationAssertion(terms:contributor obo:CL_0003033 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003033 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003033 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003033 "CL:0003033")
AnnotationAssertion(rdfs:label obo:CL_0003033 "M4 retinal ganglion cell")
SubClassOf(obo:CL_0003033 obo:CL_0000740)
SubClassOf(obo:CL_0003033 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003033 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003033 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003034 (M5 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003034 "A monostratified retinal ganglion cell that has a small soma, an assymetric dendritic field with post synaptic terminals in sublaminar layer S3.")
AnnotationAssertion(terms:contributor obo:CL_0003034 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003034 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003034 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003034 "CL:0003034")
AnnotationAssertion(rdfs:label obo:CL_0003034 "M5 retinal ganglion cell")
SubClassOf(obo:CL_0003034 obo:CL_0000740)
SubClassOf(obo:CL_0003034 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003034 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003034 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003035 (M6 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003035 "A monostratified retinal ganglion cell that contains opsin.")
AnnotationAssertion(terms:contributor obo:CL_0003035 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003035 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003035 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003035 "CL:0003035")
AnnotationAssertion(rdfs:label obo:CL_0003035 "M6 retinal ganglion cell")
SubClassOf(obo:CL_0003035 obo:CL_0000740)
SubClassOf(obo:CL_0003035 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003035 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003035 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001243))

# Class: obo:CL_0003036 (M7 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003036 "A monostratified retinal ganglion cell with large soma and large dendritic field, with medium dendritic arbor, and has dendrites in layers 2 and 5.")
AnnotationAssertion(terms:contributor obo:CL_0003036 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003036 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003036 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003036 "CL:0003036")
AnnotationAssertion(rdfs:label obo:CL_0003036 "M7 retinal ganglion cell")
SubClassOf(obo:CL_0003036 obo:CL_0000740)
SubClassOf(obo:CL_0003036 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003036 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0003037 (M7-ON retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003037 "An M7 retinal ganglion cells with synaptic terminals in S4 and is depolarized by illumination of its receptive field center.")
AnnotationAssertion(terms:contributor obo:CL_0003037 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003037 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003037 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003037 "CL:0003037")
AnnotationAssertion(rdfs:label obo:CL_0003037 "M7-ON retinal ganglion cell")
SubClassOf(obo:CL_0003037 obo:CL_0003036)
SubClassOf(obo:CL_0003037 obo:CL_4023032)
SubClassOf(obo:CL_0003037 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003038 (M7-OFF retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003038 "An M7 retinal ganglion cells with synaptic terminals in S2 and is depolarized by decreased illumination of their receptive field center")
AnnotationAssertion(terms:contributor obo:CL_0003038 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003038 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003038 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003038 "CL:0003038")
AnnotationAssertion(rdfs:label obo:CL_0003038 "M7-OFF retinal ganglion cell")
SubClassOf(obo:CL_0003038 obo:CL_0003036)
SubClassOf(obo:CL_0003038 obo:CL_4023033)
SubClassOf(obo:CL_0003038 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003039 (M8 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003039 "A monostratified retinal ganglion cell with large soma and medium dendritic field, with dense dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0003039 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003039 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003039 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003039 "CL:0003039")
AnnotationAssertion(rdfs:label obo:CL_0003039 "M8 retinal ganglion cell")
SubClassOf(obo:CL_0003039 obo:CL_0000740)
SubClassOf(obo:CL_0003039 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003039 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0003040 (M9 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003040 "A monostratified retinal ganglion cell with large soma and large dendritic field, with medium dendritic arbor, and has dendrites in layers 1 and 5.")
AnnotationAssertion(terms:contributor obo:CL_0003040 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003040 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003040 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003040 "CL:0003040")
AnnotationAssertion(rdfs:label obo:CL_0003040 "M9 retinal ganglion cell")
SubClassOf(obo:CL_0003040 obo:CL_0000740)
SubClassOf(obo:CL_0003040 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003040 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0003041 (M9-ON retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003041 "An M9 retinal ganglion cells with synaptic terminals in S2 and is depolarized by illumination of its receptive field center.")
AnnotationAssertion(terms:contributor obo:CL_0003041 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003041 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003041 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003041 "CL:0003041")
AnnotationAssertion(rdfs:label obo:CL_0003041 "M9-ON retinal ganglion cell")
SubClassOf(obo:CL_0003041 obo:CL_0003040)
SubClassOf(obo:CL_0003041 obo:CL_4023032)
SubClassOf(obo:CL_0003041 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0003042 (M9-OFF retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003042 "An M9 retinal ganglion cell with synaptic terminals in S4 that is depolarized by decreased illumination of their receptive field center")
AnnotationAssertion(terms:contributor obo:CL_0003042 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003042 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003042 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003042 "CL:0003042")
AnnotationAssertion(rdfs:label obo:CL_0003042 "M9-OFF retinal ganglion cell")
SubClassOf(obo:CL_0003042 obo:CL_0003040)
SubClassOf(obo:CL_0003042 obo:CL_4023033)
SubClassOf(obo:CL_0003042 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003043 (M10 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003043 "A monostratified retinal ganglion cell with large soma and large dendritic field, with dense dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0003043 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003043 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003043 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003043 "CL:0003043")
AnnotationAssertion(rdfs:label obo:CL_0003043 "M10 retinal ganglion cell")
SubClassOf(obo:CL_0003043 obo:CL_0000740)
SubClassOf(obo:CL_0003043 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0003043 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0003044 (M11 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003044 "A bistratified ganglion cell with small, dense dendritic fields that terminate in S1 and S3.")
AnnotationAssertion(terms:contributor obo:CL_0003044 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003044 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003044 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003044 "CL:0003044")
AnnotationAssertion(rdfs:label obo:CL_0003044 "M11 retinal ganglion cell")
SubClassOf(obo:CL_0003044 obo:CL_0000740)
SubClassOf(obo:CL_0003044 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003044 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003044 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0003044 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0003045 (M12 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003045 "A bistratified ganglion cell with larger, asymetric dendritic fields that terminate in S2 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0003045 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003045 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003045 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003045 "CL:0003045")
AnnotationAssertion(rdfs:label obo:CL_0003045 "M12 retinal ganglion cell")
SubClassOf(obo:CL_0003045 obo:CL_0000740)
SubClassOf(obo:CL_0003045 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003045 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003045 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003045 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003046 (M13 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003046 "A bistratifed retinal ganglion cell that has small, symmetric dendritic fields that terminate in S2 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0003046 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003046 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003046 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003046 "CL:0003046")
AnnotationAssertion(rdfs:label obo:CL_0003046 "M13 retinal ganglion cell")
SubClassOf(obo:CL_0003046 obo:CL_0000740)
SubClassOf(obo:CL_0003046 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003046 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003046 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0003046 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0003047 (M14 retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16626866") obo:IAO_0000115 obo:CL_0003047 "A bistratifed retinal ganglion cell that has small, symmetric dendritic fields that terminate in S1 and S4-S5.")
AnnotationAssertion(terms:contributor obo:CL_0003047 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0003047 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003047 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003047 "CL:0003047")
AnnotationAssertion(rdfs:label obo:CL_0003047 "M14 retinal ganglion cell")
SubClassOf(obo:CL_0003047 obo:CL_0000740)
SubClassOf(obo:CL_0003047 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0003047 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_0003047 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0003047 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008929))

# Class: obo:CL_0003048 (L cone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cone_cell&oldid=1111888680") obo:IAO_0000115 obo:CL_0003048 "A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm.")
AnnotationAssertion(terms:contributor obo:CL_0003048 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32555229") oboInOwl:hasExactSynonym obo:CL_0003048 "L cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29603924") oboInOwl:hasExactSynonym obo:CL_0003048 "L-cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31117170") oboInOwl:hasExactSynonym obo:CL_0003048 "long wavelength sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.7554/eLife.39166") oboInOwl:hasExactSynonym obo:CL_0003048 "long- (L) wavelength-sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1038/323623a0") oboInOwl:hasExactSynonym obo:CL_0003048 "long-wavelength cone")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003048 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003048 "CL:0003048")
AnnotationAssertion(rdfs:label obo:CL_0003048 "L cone cell")
SubClassOf(obo:CL_0003048 obo:CL_0000573)
SubClassOf(obo:CL_0003048 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001244))

# Class: obo:CL_0003049 (M cone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cone_cell&oldid=1111888680") obo:IAO_0000115 obo:CL_0003049 "A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm.")
AnnotationAssertion(terms:contributor obo:CL_0003049 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32555229") oboInOwl:hasExactSynonym obo:CL_0003049 "M cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29603924") oboInOwl:hasExactSynonym obo:CL_0003049 "M-cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31117170") oboInOwl:hasExactSynonym obo:CL_0003049 "middle wavelength sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.7554/eLife.39166") oboInOwl:hasExactSynonym obo:CL_0003049 "middle- (M) wavelength-sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153") oboInOwl:hasExactSynonym obo:CL_0003049 "middle-wavelength-sensitive (M) cone")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003049 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003049 "CL:0003049")
AnnotationAssertion(rdfs:label obo:CL_0003049 "M cone cell")
SubClassOf(obo:CL_0003049 obo:CL_0000573)
SubClassOf(obo:CL_0003049 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001224))

# Class: obo:CL_0003050 (S cone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cone_cell&oldid=1111888680") obo:IAO_0000115 obo:CL_0003050 "A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm.")
AnnotationAssertion(terms:contributor obo:CL_0003050 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32555229") oboInOwl:hasExactSynonym obo:CL_0003050 "S cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31117170") oboInOwl:hasExactSynonym obo:CL_0003050 "S-(short-wavelength sensitive) cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32555229") oboInOwl:hasExactSynonym obo:CL_0003050 "S-cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.7554/eLife.39166") oboInOwl:hasExactSynonym obo:CL_0003050 "S-cone photoreceptor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31117170") oboInOwl:hasExactSynonym obo:CL_0003050 "short wavelength sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.7554/eLife.39166") oboInOwl:hasExactSynonym obo:CL_0003050 "short- (S) wavelength-sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31117170") oboInOwl:hasExactSynonym obo:CL_0003050 "short-wavelength sensitive cone")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153") oboInOwl:hasExactSynonym obo:CL_0003050 "short-wavelength-sensitive (S) cone")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003050 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003050 "CL:0003050")
AnnotationAssertion(rdfs:label obo:CL_0003050 "S cone cell")
SubClassOf(obo:CL_0003050 obo:CL_0000573)

# Class: obo:CL_0003051 (UV cone cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0003051 "A cone cell that detects ultraviolet (UV) wavelength light.")
AnnotationAssertion(terms:contributor obo:CL_0003051 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0003051 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0003051 "CL:0003051")
AnnotationAssertion(rdfs:label obo:CL_0003051 "UV cone cell")
SubClassOf(obo:CL_0003051 obo:CL_0000573)

# Class: obo:CL_0004001 (local interneuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004001 "An interneuron whose axon stays entirely within the gray matter region where the cell body resides.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004001 "BAMS:1002")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004001 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004001 "CL:0004001")
AnnotationAssertion(rdfs:comment obo:CL_0004001 "Local interneurons form the category of interneurons whose axon stays entirely within the gray matter region where the cell body resides (Swanson, 2003, p. 245; Bota and Swanson, 2007, Fig. 3).")
AnnotationAssertion(rdfs:label obo:CL_0004001 "local interneuron")
SubClassOf(obo:CL_0004001 obo:CL_0000099)
SubClassOf(obo:CL_0004001 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002020))

# Class: obo:CL_0004115 (retinal ganglion cell B)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004115 "A monostratified retinal ganglion cell with small to medium soma and small to medium dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004115 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004115 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004115 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004115 "CL:0004115")
AnnotationAssertion(rdfs:label obo:CL_0004115 "retinal ganglion cell B")
SubClassOf(obo:CL_0004115 obo:CL_0000740)
SubClassOf(obo:CL_0004115 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0004115 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0004116 (retinal ganglion cell C)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004116 "A retinal ganglion with cell medium cell bodies and medium to large dendritic fields.")
AnnotationAssertion(terms:contributor obo:CL_0004116 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004116 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004116 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004116 "CL:0004116")
AnnotationAssertion(rdfs:comment obo:CL_0004116 "Group RGC cells are defined as having small to medium cell bodies and medium to large dendritic fields. Their morphology was more heterogeneous than that of Groups RGA and RGB. We classified cells with a large soma and a large dendritic field as RGA, cells with a small to medium to sized soma and a small to medium to sized dendritic field as RGB, and cells with a small to medium to sized soma but a medium to large dendritic field RGC.")
AnnotationAssertion(rdfs:label obo:CL_0004116 "retinal ganglion cell C")
SubClassOf(obo:CL_0004116 obo:CL_0000740)
SubClassOf(obo:CL_0004116 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0004117 (retinal ganglion cell A)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004117 "A monostratified retinal ganglion cell with large soma and large dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004117 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004117 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004117 "BAMS:1009")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004117 "alpha cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004117 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004117 "CL:0004117")
AnnotationAssertion(rdfs:comment obo:CL_0004117 "This group includes all of the large bodied/large field RGCs in the rat. Group RGA cells have large somata (15 to 39 micrometers in diameter) and large, radially branching dendritic fields (235 to 748 micrometers in diameter), and many exhibit tracer coupling.")
AnnotationAssertion(rdfs:label obo:CL_0004117 "retinal ganglion cell A")
SubClassOf(obo:CL_0004117 obo:CL_0000740)
SubClassOf(obo:CL_0004117 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063))
SubClassOf(obo:CL_0004117 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0004119 (retinal ganglion cell B1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004119 "A retinal ganglion cell B that has medium body size, medium dendritic field and dense dendritic arbor, and has post synaptic terminals in S2.")
AnnotationAssertion(terms:contributor obo:CL_0004119 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004119 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004119 "BAMS:1047")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004119 "retinal ganglion cell B4")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004119 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004119 "CL:0004119")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") rdfs:comment obo:CL_0004119 "Could not distingush between B1 and B4 from paper.")
AnnotationAssertion(rdfs:label obo:CL_0004119 "retinal ganglion cell B1")
SubClassOf(obo:CL_0004119 obo:CL_0004115)
SubClassOf(obo:CL_0004119 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0004120 (retinal ganglion cell A1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004120 "A retinal ganglion A cell found in the retina with large somata, often polygonal in shape. The dendritic fields consist of three to seven stout dendrites that are sparce near soma. Dendrites terminate in S4.")
AnnotationAssertion(terms:contributor obo:CL_0004120 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004120 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0004120 "type I")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004120 "BAMS:1045")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004120 "inner alpha retinal ganglion cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004120 "cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004120 "I-2")
AnnotationAssertion(oboInOwl:id obo:CL_0004120 "CL:0004120")
AnnotationAssertion(rdfs:label obo:CL_0004120 "retinal ganglion cell A1")
SubClassOf(obo:CL_0004120 obo:CL_0004117)
SubClassOf(obo:CL_0004120 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004121 (retinal ganglion cell B2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004121 "A retinal ganglion cell B that has a very small but very dense dendritic field, and has post synaptic terminals in S2.")
AnnotationAssertion(terms:contributor obo:CL_0004121 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004121 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004121 "BAMS:1048")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004121 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004121 "CL:0004121")
AnnotationAssertion(rdfs:label obo:CL_0004121 "retinal ganglion cell B2")
SubClassOf(obo:CL_0004121 obo:CL_0004115)
SubClassOf(obo:CL_0004121 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0004124 (retinal ganglion cell C1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004124 "A retinal ganglion cell C inner that has medium dendritic diversity.")
AnnotationAssertion(terms:contributor obo:CL_0004124 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004124 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004124 "BAMS:1050")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004124 "cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004124 "MTN projecting")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004124 "ON-direction-selective")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004124 "delta")
AnnotationAssertion(oboInOwl:id obo:CL_0004124 "CL:0004124")
AnnotationAssertion(rdfs:label obo:CL_0004124 "retinal ganglion cell C1")
SubClassOf(obo:CL_0004124 obo:CL_0003024)

# Class: obo:CL_0004125 (retinal ganglion cell C2 inner)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004125 "A retinal ganglion cell C inner that has dense dendritic diversity.")
AnnotationAssertion(terms:contributor obo:CL_0004125 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004125 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004125 "BAMS:1067")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004125 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004125 "CL:0004125")
AnnotationAssertion(rdfs:label obo:CL_0004125 "retinal ganglion cell C2 inner")
SubClassOf(obo:CL_0004125 obo:CL_0003024)

# Class: obo:CL_0004126 (retinal ganglion cell C2 outer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004126 "A retinal ganglion cell C outer that has symmetrical and dense dendritic dendritic tree with a large dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004126 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004126 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004126 "BAMS:1066")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004126 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004126 "CL:0004126")
AnnotationAssertion(rdfs:label obo:CL_0004126 "retinal ganglion cell C2 outer")
SubClassOf(obo:CL_0004126 obo:CL_0003020)

# Class: obo:CL_0004137 (retinal ganglion cell A2 inner)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004137 "A retinal ganglion A2 cell with dendrites terminating in S4.")
AnnotationAssertion(terms:contributor obo:CL_0004137 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004137 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004137 "BAMS:1061")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004137 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004137 "CL:0004137")
AnnotationAssertion(rdfs:label obo:CL_0004137 "retinal ganglion cell A2 inner")
SubClassOf(obo:CL_0004137 obo:CL_0004138)
SubClassOf(obo:CL_0004137 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004138 (retinal ganglion cell A2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004138 "A retinal ganglion A cell with dense arbor near soma.")
AnnotationAssertion(terms:contributor obo:CL_0004138 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004138 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004138 "outer alpha retinal ganglion cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004138 "cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004138 "I-1")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0004138 "type I")
AnnotationAssertion(oboInOwl:id obo:CL_0004138 "CL:0004138")
AnnotationAssertion(rdfs:label obo:CL_0004138 "retinal ganglion cell A2")
SubClassOf(obo:CL_0004138 obo:CL_0004117)

# Class: obo:CL_0004139 (retinal ganglion cell A2 outer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12209831") obo:IAO_0000115 obo:CL_0004139 "A retinal ganglion A2 cell with dendrites terminating in S2.")
AnnotationAssertion(terms:contributor obo:CL_0004139 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004139 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004139 "BAMS:1065")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004139 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004139 "CL:0004139")
AnnotationAssertion(rdfs:label obo:CL_0004139 "retinal ganglion cell A2 outer")
SubClassOf(obo:CL_0004139 obo:CL_0004138)
SubClassOf(obo:CL_0004139 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0004161 (510 nm-cone)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004161 "A cone whose sensitivity measurements have an average spectral peak of 510 nm. These cones are described in rat.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0004161 obo:NCBITaxon_9989)
AnnotationAssertion(terms:contributor obo:CL_0004161 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(Annotation(rdfs:label "MB") oboInOwl:hasDbXref obo:CL_0004161 "BAMS:1028")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004161 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004161 "CL:0004161")
AnnotationAssertion(rdfs:label obo:CL_0004161 "510 nm-cone")
SubClassOf(obo:CL_0004161 obo:CL_0003049)

# Class: obo:CL_0004162 (360 nm-cone)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004162 "A cone whose sensitivity measurements have an average spectral peak of 358.2 nm. These cones are described in rat.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0004162 obo:NCBITaxon_9989)
AnnotationAssertion(terms:contributor obo:CL_0004162 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(Annotation(rdfs:label "MB") oboInOwl:hasDbXref obo:CL_0004162 "BAMS:1029")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004162 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004162 "CL:0004162")
AnnotationAssertion(rdfs:comment obo:CL_0004162 "The photopigment curves that provide best fits to...sensitivity measurements have an average spectral peak of 358.2 nm.")
AnnotationAssertion(rdfs:label obo:CL_0004162 "360 nm-cone")
SubClassOf(obo:CL_0004162 obo:CL_0003051)

# Class: obo:CL_0004183 (retinal ganglion cell B3)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004183 "A monostratified retinal ganglion cell with medium soma, sparse dendritic tree, and medium dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004183 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004183 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0004183 "BAMS:1049")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004183 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004183 "CL:0004183")
AnnotationAssertion(rdfs:comment obo:CL_0004183 "Sixty to eighty neurons with small somata (12 to 24 micrometers in diameter), small dendritic fields (99 to 289 micrometers in diameter), and small axonal diameters (04. to 07. micrometers in diameter) make up Group RGB. We classified cells with a large soma and a large dendritic field as RGA, cells with a small to medium to sized soma and a small to medium to sized dendritic field as RGB, and cells with a small to medium to sized soma but a medium to large dendritic field RGC.")
AnnotationAssertion(rdfs:label obo:CL_0004183 "retinal ganglion cell B3")
SubClassOf(obo:CL_0004183 obo:CL_0004115)

# Class: obo:CL_0004213 (type 3a cone bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19129389") obo:IAO_0000115 obo:CL_0004213 "A type of type 3 cone bipolar cell with distinctive curly dendrites.")
AnnotationAssertion(terms:contributor obo:CL_0004213 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004213 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004213 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004213 "CL:0004213")
AnnotationAssertion(rdfs:label obo:CL_0004213 "type 3a cone bipolar cell")
SubClassOf(obo:CL_0004213 obo:CL_0000755)
SubClassOf(obo:CL_0004213 ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0030425 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000405))))

# Class: obo:CL_0004214 (type 3b cone bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19129389") obo:IAO_0000115 obo:CL_0004214 "A type of type 3 cone bipolar cell with distinctive crescent-shaped dendrites.")
AnnotationAssertion(terms:contributor obo:CL_0004214 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004214 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004214 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004214 "CL:0004214")
AnnotationAssertion(rdfs:label obo:CL_0004214 "type 3b cone bipolar cell")
SubClassOf(obo:CL_0004214 obo:CL_0000755)
SubClassOf(obo:CL_0004214 ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0030425 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001870))))

# Class: obo:CL_0004215 (type 5a cone bipolar cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004215 "A type 5 cone bipolar cell with narrowly stratified post synaptic terminals.")
AnnotationAssertion(terms:contributor obo:CL_0004215 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004215 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004215 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004215 "CL:0004215")
AnnotationAssertion(rdfs:label obo:CL_0004215 "type 5a cone bipolar cell")
SubClassOf(obo:CL_0004215 obo:CL_0000757)

# Class: obo:CL_0004216 (type 5b cone bipolar cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0004216 "A type 5 cone bipolar cell with diffuse axonal branches.")
AnnotationAssertion(terms:contributor obo:CL_0004216 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004216 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004216 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004216 "CL:0004216")
AnnotationAssertion(rdfs:label obo:CL_0004216 "type 5b cone bipolar cell")
SubClassOf(obo:CL_0004216 obo:CL_0000757)

# Class: obo:CL_0004217 (H1 horizontal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8571130") obo:IAO_0000115 obo:CL_0004217 "A horizontal cell with a large cell body, thick dendrites, and a large dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0004217 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004217 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004217 "A Horizontal Cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004217 "cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0004217 "H1")
AnnotationAssertion(oboInOwl:id obo:CL_0004217 "CL:0004217")
AnnotationAssertion(rdfs:label obo:CL_0004217 "H1 horizontal cell")
SubClassOf(obo:CL_0004217 obo:CL_0000745)
SubClassOf(obo:CL_0004217 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0030424))

# Class: obo:CL_0004218 (H2 horizontal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8571130") obo:IAO_0000115 obo:CL_0004218 "A horizontal cell with a small cell body, thin dendrites, and small dendritic arbor.")
AnnotationAssertion(terms:contributor obo:CL_0004218 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004218 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0004218 "B Horizontal Cell")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004218 "cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41598-020-66092-9") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0004218 "H2")
AnnotationAssertion(oboInOwl:id obo:CL_0004218 "CL:0004218")
AnnotationAssertion(rdfs:label obo:CL_0004218 "H2 horizontal cell")
SubClassOf(obo:CL_0004218 obo:CL_0000745)
SubClassOf(obo:CL_0004218 ObjectSomeValuesFrom(obo:RO_0002120 obo:GO_0044316))

# Class: obo:CL_0004219 (A2 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24246263") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004219 "A bistratifed retinal amacrine cell with a small dendritic field, dendrite stratification in S1-S2, and a second dendrite stratification in S5. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004219 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004219 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004219 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004219 "CL:0004219")
AnnotationAssertion(rdfs:label obo:CL_0004219 "A2 amacrine cell")
SubClassOf(obo:CL_0004219 obo:CL_0004251)
SubClassOf(obo:CL_0004219 obo:CL_4030028)
SubClassOf(obo:CL_0004219 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004219 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008926))
SubClassOf(obo:CL_0004219 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008927))

# Class: obo:CL_0004220 (flag amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004220 "An amacrine cell with a small, asymteric dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004220 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004220 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004220 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004220 "CL:0004220")
AnnotationAssertion(rdfs:label obo:CL_0004220 "flag amacrine cell")
SubClassOf(obo:CL_0004220 obo:CL_0004251)

# Class: obo:CL_0004221 (flag A amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24246263") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004221 "A flag amacrine cell with post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004221 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004221 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004221 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004221 "CL:0004221")
AnnotationAssertion(rdfs:label obo:CL_0004221 "flag A amacrine cell")
SubClassOf(obo:CL_0004221 obo:CL_0004220)
SubClassOf(obo:CL_0004221 obo:CL_4030028)
SubClassOf(obo:CL_0004221 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004221 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004222 (flag B amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24246263") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004222 "A flag amacrine cell with post-synaptic terminals in S3, S4, and S5. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004222 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004222 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004222 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004222 "CL:0004222")
AnnotationAssertion(rdfs:label obo:CL_0004222 "flag B amacrine cell")
SubClassOf(obo:CL_0004222 obo:CL_0004220)
SubClassOf(obo:CL_0004222 obo:CL_4030028)
SubClassOf(obo:CL_0004222 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004222 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))
SubClassOf(obo:CL_0004222 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008926))

# Class: obo:CL_0004223 (AB diffuse-1 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004223 "A amacrine cell with a small dendritic field and post-synaptic terminals in S1, S2, S3, and S4. AB diffuse-1 amacrine cells have a tent-shaped dendritic arbor and undulate dendrites.")
AnnotationAssertion(terms:contributor obo:CL_0004223 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004223 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004223 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004223 "CL:0004223")
AnnotationAssertion(rdfs:label obo:CL_0004223 "AB diffuse-1 amacrine cell")
SubClassOf(obo:CL_0004223 obo:CL_0004251)
SubClassOf(obo:CL_0004223 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004223 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004223 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004223 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004224 (AB diffuse-2 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004224 "A broadly stratifying amacrine cell that has a small dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004224 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004224 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004224 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004224 "CL:0004224")
AnnotationAssertion(rdfs:label obo:CL_0004224 "AB diffuse-2 amacrine cell")
SubClassOf(obo:CL_0004224 obo:CL_0004251)
SubClassOf(obo:CL_0004224 obo:CL_4030028)
SubClassOf(obo:CL_0004224 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004224 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004225 (spider amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004225 "A broadly stratifying amacrine cell with a small dendritic field, straight dendrites and post-synaptic terminals in S1, S2, and S3.")
AnnotationAssertion(terms:contributor obo:CL_0004225 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004225 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004225 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004225 "CL:0004225")
AnnotationAssertion(rdfs:label obo:CL_0004225 "spider amacrine cell")
SubClassOf(obo:CL_0004225 obo:CL_0004251)
SubClassOf(obo:CL_0004225 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004225 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004225 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004226 (monostratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004226 "An amacrine cell with a small dendritic field with post-synaptic terminals in S3 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004226 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004226 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004226 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004226 "CL:0004226")
AnnotationAssertion(rdfs:label obo:CL_0004226 "monostratified amacrine cell")
EquivalentClasses(obo:CL_0004226 ObjectIntersectionOf(obo:CL_0004251 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063)))
SubClassOf(obo:CL_0004226 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004226 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004227 (flat bistratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25630271") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004227 "A bistratified amacrine cell with a small dendritic field. Flat bistratified amacrine cells have post-synaptic terminals both on the border of S1 and S2, and on the border of S3 and S4. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004227 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004227 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004227 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004227 "CL:0004227")
AnnotationAssertion(rdfs:label obo:CL_0004227 "flat bistratified amacrine cell")
SubClassOf(obo:CL_0004227 obo:CL_0004251)
SubClassOf(obo:CL_0004227 obo:CL_4030028)
SubClassOf(obo:CL_0004227 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004227 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009738))
SubClassOf(obo:CL_0004227 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009739))

# Class: obo:CL_0004228 (broad diffuse amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004228 "An amacrine cell with a small dendritic field that has post-synaptic terminals in S1, S2, S3, and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004228 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004228 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004228 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004228 "CL:0004228")
AnnotationAssertion(rdfs:label obo:CL_0004228 "broad diffuse amacrine cell")
SubClassOf(obo:CL_0004228 obo:CL_0004251)
SubClassOf(obo:CL_0004228 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004228 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004228 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004228 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004229 (A2-like amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004229 "A bistratified amacrine cell with a small dendritic field that has dendrite stratification in S2, and in S3 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004229 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004229 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004229 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004229 "CL:0004229")
AnnotationAssertion(rdfs:label obo:CL_0004229 "A2-like amacrine cell")
SubClassOf(obo:CL_0004229 obo:CL_0004251)
SubClassOf(obo:CL_0004229 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004229 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004229 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009731))

# Class: obo:CL_0004230 (diffuse bistratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004230 "A bistratified amacrine cell with a small dendritic field that has post-synaptic terminals in S1 and the border of S1-S2, and termination of a second arbor within the border of S2-S3 and S3.")
AnnotationAssertion(terms:contributor obo:CL_0004230 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004230 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004230 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004230 "CL:0004230")
AnnotationAssertion(rdfs:label obo:CL_0004230 "diffuse bistratified amacrine cell")
SubClassOf(obo:CL_0004230 obo:CL_0004251)
SubClassOf(obo:CL_0004230 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004230 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004230 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004230 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009738))
SubClassOf(obo:CL_0004230 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009852))

# Class: obo:CL_0004231 (recurving diffuse amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004231 "A broadly stratifying amacrine cell with a small dendritic field and a complex dendritic arbor. Recurving diffuse amacrine cells have post-synaptic terminals in S2, S3, and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004231 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004231 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004231 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004231 "CL:0004231")
AnnotationAssertion(rdfs:label obo:CL_0004231 "recurving diffuse amacrine cell")
SubClassOf(obo:CL_0004231 obo:CL_0004251)
SubClassOf(obo:CL_0004231 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004231 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004231 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004232 (starburst amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004232 "An amacrine cell with a flat dendritic arbor and a medium dendritic field. Starburst amacrine cells have post-synaptic terminals in S2. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and acetylcholine.")
AnnotationAssertion(terms:contributor obo:CL_0004232 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004232 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004232 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004232 "CL:0004232")
AnnotationAssertion(rdfs:label obo:CL_0004232 "starburst amacrine cell")
SubClassOf(obo:CL_0004232 obo:CL_0000561)
SubClassOf(obo:CL_0004232 obo:CL_4030027)
SubClassOf(obo:CL_0004232 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055))
SubClassOf(obo:CL_0004232 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))

# Class: obo:CL_0004233 (DAPI-3 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9194315") obo:IAO_0000115 obo:CL_0004233 "An amacrine cell with a medium dendritic field and post-synaptic terminals that stratify at S2, with a second stratification that occurs in S3 and S4. This cell type releases the neurotransmitter glycine.")
AnnotationAssertion(terms:contributor obo:CL_0004233 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004233 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004233 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004233 "CL:0004233")
AnnotationAssertion(rdfs:label obo:CL_0004233 "DAPI-3 amacrine cell")
SubClassOf(obo:CL_0004233 obo:CL_0004252)
SubClassOf(obo:CL_0004233 obo:CL_4030028)
SubClassOf(obo:CL_0004233 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004233 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004233 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009731))

# Class: obo:CL_0004234 (diffuse multistratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004234 "An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, and in S3-S4.")
AnnotationAssertion(terms:contributor obo:CL_0004234 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004234 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004234 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004234 "CL:0004234")
AnnotationAssertion(rdfs:label obo:CL_0004234 "diffuse multistratified amacrine cell")
SubClassOf(obo:CL_0004234 obo:CL_0004252)
SubClassOf(obo:CL_0004234 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004234 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009731))

# Class: obo:CL_0004235 (AB broad diffuse-1 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004235 "An amacrine cell with a medium dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA).")
AnnotationAssertion(terms:contributor obo:CL_0004235 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004235 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004235 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004235 "CL:0004235")
AnnotationAssertion(rdfs:label obo:CL_0004235 "AB broad diffuse-1 amacrine cell")
SubClassOf(obo:CL_0004235 obo:CL_0004252)
SubClassOf(obo:CL_0004235 obo:CL_4030027)
SubClassOf(obo:CL_0004235 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004235 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004236 (AB broad diffuse-2 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004236 "An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA).")
AnnotationAssertion(terms:contributor obo:CL_0004236 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004236 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004236 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004236 "CL:0004236")
AnnotationAssertion(rdfs:label obo:CL_0004236 "AB broad diffuse-2 amacrine cell")
SubClassOf(obo:CL_0004236 obo:CL_0004252)
SubClassOf(obo:CL_0004236 obo:CL_4030027)
SubClassOf(obo:CL_0004236 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004236 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004236 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004237 (fountain amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10614594") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004237 "A retinal amacrine cell with a medium dendritic field and post-synaptic terminals in S1, S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA).")
AnnotationAssertion(terms:contributor obo:CL_0004237 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004237 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004237 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004237 "CL:0004237")
AnnotationAssertion(rdfs:label obo:CL_0004237 "fountain amacrine cell")
SubClassOf(obo:CL_0004237 obo:CL_0004252)
SubClassOf(obo:CL_0004237 obo:CL_4030027)
SubClassOf(obo:CL_0004237 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004237 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004237 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))
SubClassOf(obo:CL_0004237 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004238 (asymmetric bistratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004238 "A bistratified amacrine cell with a medium dendritic field, a flat and sparse dendritic arbor, and post-synaptic terminals at the intersections of S1 and S2, and S3 and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004238 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004238 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004238 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004238 "CL:0004238")
AnnotationAssertion(rdfs:label obo:CL_0004238 "asymmetric bistratified amacrine cell")
SubClassOf(obo:CL_0004238 obo:CL_0004252)
SubClassOf(obo:CL_0004238 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004238 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009738))
SubClassOf(obo:CL_0004238 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0009739))

# Class: obo:CL_0004239 (wavy bistratified amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004239 "A bistratified amacrine cell with a medium dendritic field and post-synaptic terminals in S1-S2, and S4.")
AnnotationAssertion(terms:contributor obo:CL_0004239 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004239 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004239 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004239 "CL:0004239")
AnnotationAssertion(rdfs:label obo:CL_0004239 "wavy bistratified amacrine cell")
SubClassOf(obo:CL_0004239 obo:CL_0004252)
SubClassOf(obo:CL_0004239 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062))
SubClassOf(obo:CL_0004239 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))
SubClassOf(obo:CL_0004239 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008923))
SubClassOf(obo:CL_0004239 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004240 (WF1 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004240 "An amacrine cell with a wide dendritic field, dendrites in S1, and post-synaptic terminals in S1.")
AnnotationAssertion(terms:contributor obo:CL_0004240 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004240 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004240 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004240 "CL:0004240")
AnnotationAssertion(rdfs:label obo:CL_0004240 "WF1 amacrine cell")
SubClassOf(obo:CL_0004240 obo:CL_0004253)
SubClassOf(obo:CL_0004240 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))

# Class: obo:CL_0004241 (WF2 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004241 "An amacrine cell with a wide dendritic field, dendrites in S2, and post-synaptic terminals in S1.")
AnnotationAssertion(terms:contributor obo:CL_0004241 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004241 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004241 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004241 "CL:0004241")
AnnotationAssertion(rdfs:label obo:CL_0004241 "WF2 amacrine cell")
SubClassOf(obo:CL_0004241 obo:CL_0004253)
SubClassOf(obo:CL_0004241 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008922))

# Class: obo:CL_0004242 (WF3-1 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004242 "An amacrine cell with a wide dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites of this cell type are straight and minimally branched.")
AnnotationAssertion(terms:contributor obo:CL_0004242 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004242 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004242 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004242 "CL:0004242")
AnnotationAssertion(rdfs:label obo:CL_0004242 "WF3-1 amacrine cell")
SubClassOf(obo:CL_0004242 obo:CL_0004253)
SubClassOf(obo:CL_0004242 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004243 (WF3-2 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004243 "An amacrine cell with a wild dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites have spikes, cross over each other, and cover a larger volume than dendrties of W3-1 retinal amacrine cells.")
AnnotationAssertion(terms:contributor obo:CL_0004243 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004243 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004243 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004243 "CL:0004243")
AnnotationAssertion(rdfs:label obo:CL_0004243 "WF3-2 amacrine cell")
SubClassOf(obo:CL_0004243 obo:CL_0004253)
SubClassOf(obo:CL_0004243 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008924))

# Class: obo:CL_0004244 (WF4 amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004244 "An amacrine cell with a wide dendritic field, dendrites in S4, and post-synaptic terminals in S4.")
AnnotationAssertion(terms:contributor obo:CL_0004244 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004244 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004244 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004244 "CL:0004244")
AnnotationAssertion(rdfs:label obo:CL_0004244 "WF4 amacrine cell")
SubClassOf(obo:CL_0004244 obo:CL_0004253)
SubClassOf(obo:CL_0004244 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008925))

# Class: obo:CL_0004245 (indoleamine-accumulating amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12486181") Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004245 "An amacrine cell with a wide dendritic field and post-synaptic terminals in S5. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and serotonin.")
AnnotationAssertion(terms:contributor obo:CL_0004245 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004245 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004245 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004245 "CL:0004245")
AnnotationAssertion(rdfs:label obo:CL_0004245 "indoleamine-accumulating amacrine cell")
SubClassOf(obo:CL_0004245 obo:CL_0004253)
SubClassOf(obo:CL_0004245 obo:CL_4030027)
SubClassOf(obo:CL_0004245 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060096))
SubClassOf(obo:CL_0004245 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0008926))

# Class: obo:CL_0004246 (monostratified cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004246 "A central nervous system neuron that stratifies at one and only one location.")
AnnotationAssertion(terms:contributor obo:CL_0004246 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004246 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004246 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004246 "CL:0004246")
AnnotationAssertion(rdfs:label obo:CL_0004246 "monostratified cell")
EquivalentClasses(obo:CL_0004246 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070063) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017)))

# Class: obo:CL_0004247 (bistratified cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-5260-9315") obo:IAO_0000115 obo:CL_0004247 "A neuron that stratifies dendrites at two and only two locations.")
AnnotationAssertion(terms:contributor obo:CL_0004247 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004247 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004247 "CL:0004247")
AnnotationAssertion(rdfs:label obo:CL_0004247 "bistratified cell")
EquivalentClasses(obo:CL_0004247 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062)))
SubClassOf(obo:CL_0004247 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_0004250 (bistratified retinal amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004250 "An amicrine that stratifies dendrites at two and only two locations.")
AnnotationAssertion(terms:contributor obo:CL_0004250 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004250 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004250 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004250 "CL:0004250")
AnnotationAssertion(rdfs:label obo:CL_0004250 "bistratified retinal amacrine cell")
EquivalentClasses(obo:CL_0004250 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070062)))

# Class: obo:CL_0004251 (narrow field retinal amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004251 "An amicrine that has a narrow dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004251 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004251 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004251 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004251 "CL:0004251")
AnnotationAssertion(rdfs:label obo:CL_0004251 "narrow field retinal amacrine cell")
SubClassOf(obo:CL_0004251 obo:CL_0000561)

# Class: obo:CL_0004252 (medium field retinal amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004252 "An amicrine that has a medium dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004252 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004252 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004252 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004252 "CL:0004252")
AnnotationAssertion(rdfs:label obo:CL_0004252 "medium field retinal amacrine cell")
SubClassOf(obo:CL_0004252 obo:CL_0000561)

# Class: obo:CL_0004253 (wide field retinal amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9620701") obo:IAO_0000115 obo:CL_0004253 "An amicrine that has a wide dendritic field.")
AnnotationAssertion(terms:contributor obo:CL_0004253 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_0004253 "https://orcid.org/0000-0002-5260-9315")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_0004253 "cell")
AnnotationAssertion(oboInOwl:id obo:CL_0004253 "CL:0004253")
AnnotationAssertion(rdfs:label obo:CL_0004253 "wide field retinal amacrine cell")
SubClassOf(obo:CL_0004253 obo:CL_0000561)

# Class: obo:CL_0005000 (spinal cord interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005000 "A CNS interneuron located in the spinal cord.")
AnnotationAssertion(rdfs:comment obo:CL_0005000 "Is_a interneuron, part_of UBERON:0002240.")
AnnotationAssertion(rdfs:label obo:CL_0005000 "spinal cord interneuron")
EquivalentClasses(obo:CL_0005000 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002240)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0005000 obo:CL_0000099)

# Class: obo:CL_0005001 (iridoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005001 "A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore.")
AnnotationAssertion(rdfs:comment obo:CL_0005001 "Derived from UBERON:0002342 neural crest.")
AnnotationAssertion(rdfs:label obo:CL_0005001 "iridoblast")
SubClassOf(obo:CL_0005001 obo:CL_0011026)
SubClassOf(obo:CL_0005001 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0005002 (xanthoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005002 "A non-terminally differentiated cell that differentiates into a xanthophore.")
AnnotationAssertion(rdfs:label obo:CL_0005002 "xanthoblast")
SubClassOf(obo:CL_0005002 obo:CL_0011026)
SubClassOf(obo:CL_0005002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0005003 (leucoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005003 "A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore.")
AnnotationAssertion(rdfs:label obo:CL_0005003 "leucoblast")
SubClassOf(obo:CL_0005003 obo:CL_0011026)
SubClassOf(obo:CL_0005003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0005004 (pigment erythroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005004 "A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore.")
AnnotationAssertion(rdfs:label obo:CL_0005004 "pigment erythroblast")
SubClassOf(obo:CL_0005004 obo:CL_0011026)
SubClassOf(obo:CL_0005004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0005005 (cyanoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005005 "A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore.")
AnnotationAssertion(rdfs:label obo:CL_0005005 "cyanoblast")
SubClassOf(obo:CL_0005005 obo:CL_0011026)
SubClassOf(obo:CL_0005005 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0005006 (ionocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17555741") Annotation(oboInOwl:hasDbXref "PMID:19268451") obo:IAO_0000115 obo:CL_0005006 "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment.")
AnnotationAssertion(rdfs:label obo:CL_0005006 "ionocyte")
SubClassOf(obo:CL_0005006 obo:CL_0000066)

# Class: obo:CL_0005007 (Kolmer-Agduhr neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18680739") obo:IAO_0000115 obo:CL_0005007 "Kolmer-Agduhr neurons are ciliated GABAergic neurons that contact the central canal of the spinal cord and have ipsilateral ascending axons.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005007 "KA cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15539490") oboInOwl:hasExactSynonym obo:CL_0005007 "KA interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9634146") oboInOwl:hasExactSynonym obo:CL_0005007 "KA neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005007 "Kolmer-Agduhr cell")
AnnotationAssertion(rdfs:label obo:CL_0005007 "Kolmer-Agduhr neuron")
SubClassOf(obo:CL_0005007 obo:CL_0000617)
SubClassOf(obo:CL_0005007 obo:CL_0005000)

# Class: obo:CL_0005008 (macular hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:cvs") obo:IAO_0000115 obo:CL_0005008 "An auditory hair cell located in the macula that is sensitive to auditory stimuli.")
AnnotationAssertion(rdfs:label obo:CL_0005008 "macular hair cell")
EquivalentClasses(obo:CL_0005008 ObjectIntersectionOf(obo:CL_0000202 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000054)))
SubClassOf(obo:CL_0005008 obo:CL_0000202)

# Class: obo:CL_0005009 (renal principal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005009 "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system.")
AnnotationAssertion(rdfs:label obo:CL_0005009 "renal principal cell")
SubClassOf(obo:CL_0005009 obo:CL_0000075)
SubClassOf(obo:CL_0005009 obo:CL_0002518)

# Class: obo:CL_0005010 (renal intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005010 "A cuboidal epithelial cell of the kidney that regulates acid/base balance.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0005010 "FMA:86560")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005010 "intercalated cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") rdfs:comment obo:CL_0005010 "Intercalated cells are also called “mitochondria-rich cells”, reflecting the high levels of round mitochondria at their apical pole, or in their cytoplasm, a distribution that is quite different from that of other kidney tubule cells, which accumulated mitochondria around the basolateral membrane. These cells also have numerous irregular apical microvilli compared with the surrounding segment-specific cells. Intercalated cells lack a central cilium, at least in the cortex, which also differentiates them from the adjacent principal cells.")
AnnotationAssertion(rdfs:label obo:CL_0005010 "renal intercalated cell")
SubClassOf(obo:CL_0005010 obo:CL_0000075)
SubClassOf(obo:CL_0005010 obo:CL_0002078)
SubClassOf(obo:CL_0005010 obo:CL_0002518)
SubClassOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001285))

# Class: obo:CL_0005011 (renal alpha-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005011 "A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") oboInOwl:hasExactSynonym obo:CL_0005011 "type A intercalated cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") oboInOwl:hasExactSynonym obo:CL_0005011 "type A-IC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") rdfs:comment obo:CL_0005011 "Type A intercalated cells are the more abundant type of intercalated cell in the outer stripe of the outer medulla in most mammalian species.")
AnnotationAssertion(rdfs:label obo:CL_0005011 "renal alpha-intercalated cell")
SubClassOf(obo:CL_0005011 obo:CL_0005010)
SubClassOf(obo:CL_0005011 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046717))

# Class: obo:CL_0005012 (multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") Annotation(oboInOwl:hasDbXref "PMID:28400610") Annotation(oboInOwl:hasDbXref "PMID:30422572") Annotation(oboInOwl:hasDbXref "PMID:38032388") obo:IAO_0000115 obo:CL_0005012 "A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface.")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0005012 "multi-ciliated cell"@en)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0005012 "multiciliated cell"@en)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005012 "multi-ciliated epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005012 "multiciliated epithelial cell"@en)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0005012 "MCC"@en)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22118931") Annotation(oboInOwl:hasDbXref "PMID:23959957") Annotation(oboInOwl:hasDbXref "PMID:25729351") Annotation(oboInOwl:hasDbXref "PMID:26378583") rdfs:comment obo:CL_0005012 "While the term 'multi-ciliated epithelial cell' refers to cells with multiple motile cilia, there are exceptions where epithelial cells may have multiple non-motile cilia. Examples include olfactory sensory neurons, which have non-motile cilia for sensory detection, and choroid plexus epithelial cells, which possess multiple non-motile cilia with transient motility during development. Multiciliated cells are essential for human health, and their dysfunction can lead to various diseases known as ciliopathies, such as primary ciliary dyskinesia. This condition affects the respiratory system, brain ventricles, and reproductive system, leading to chronic respiratory infections, hydrocephalus, and infertility")
AnnotationAssertion(rdfs:label obo:CL_0005012 "multiciliated epithelial cell")
EquivalentClasses(obo:CL_0005012 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_0005013 (single ciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005013 "A ciliated epithelial cell with a single cilium.")
AnnotationAssertion(rdfs:label obo:CL_0005013 "single ciliated epithelial cell")
SubClassOf(obo:CL_0005013 obo:CL_0000066)
SubClassOf(obo:CL_0005013 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929))

# Class: obo:CL_0005014 (auditory epithelial supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0005014 "A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005014 "auditory epithelial support cell")
AnnotationAssertion(rdfs:label obo:CL_0005014 "auditory epithelial supporting cell")
SubClassOf(obo:CL_0005014 obo:CL_0000630)
SubClassOf(obo:CL_0005014 obo:CL_0000710)
SubClassOf(obo:CL_0005014 obo:CL_0002491)

# Class: obo:CL_0005015 (inner phalangeal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005015 "An auditory epithelial support cell that surrounds the nerve fibers and synapses of the auditory inner hair cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0005015 "FMA:79801")
AnnotationAssertion(rdfs:label obo:CL_0005015 "inner phalangeal cell")
SubClassOf(obo:CL_0005015 obo:CL_0002165)

# Class: obo:CL_0005016 (obsolete apical cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:TB") obo:IAO_0000115 obo:CL_0005016 "Obsolete. Use PO:0030007 from Plant Ontology instead. The apical cell is the upper cell formed after the first division of a plant zygote.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0005016 obo:PO_0030007)
AnnotationAssertion(rdfs:label obo:CL_0005016 "obsolete apical cell")
AnnotationAssertion(owl:deprecated obo:CL_0005016 "true"^^xsd:boolean)

# Class: obo:CL_0005017 (obsolete plant basal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "TAIR:TB") obo:IAO_0000115 obo:CL_0005017 "Obsolete. Use PO:0002002 from Plant Ontology instead. The lower cell formed after the first division of a plant zygote.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0005017 obo:PO_0002002)
AnnotationAssertion(rdfs:label obo:CL_0005017 "obsolete plant basal cell")
AnnotationAssertion(owl:deprecated obo:CL_0005017 "true"^^xsd:boolean)

# Class: obo:CL_0005018 (ghrelin secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:curator") obo:IAO_0000115 obo:CL_0005018 "A cell that secretes ghrelin, the peptide hormone that stimulates hunger.")
AnnotationAssertion(rdfs:label obo:CL_0005018 "ghrelin secreting cell")
EquivalentClasses(obo:CL_0005018 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036321)))

# Class: obo:CL_0005019 (pancreatic epsilon cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14970313") obo:IAO_0000115 obo:CL_0005019 "Ghrelin secreting cells found in the endocrine pancreas.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005019 "pancreatic E cell")
AnnotationAssertion(rdfs:comment obo:CL_0005019 "In mammals the endocrine pancreas is called the Islets of Langerhans.")
AnnotationAssertion(rdfs:label obo:CL_0005019 "pancreatic epsilon cell")
EquivalentClasses(obo:CL_0005019 ObjectIntersectionOf(obo:CL_0008024 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036321)))
SubClassOf(obo:CL_0005019 obo:CL_0005018)

# Class: obo:CL_0005020 (lymphangioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005020 "Lymphatic progenitor cells.")
AnnotationAssertion(terms:contributor obo:CL_0005020 <https://orcid.org/0000-0002-2244-7917>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0005020 "2012-01-12T04:44:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0005020 "Usually express Prox1, or prox1b.")
AnnotationAssertion(rdfs:label obo:CL_0005020 "lymphangioblast")
EquivalentClasses(obo:CL_0005020 ObjectIntersectionOf(obo:CL_0000048 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0004536)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0005020 obo:CL_0000048)

# Class: obo:CL_0005021 (mesenchymal lymphangioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15624319") Annotation(oboInOwl:hasDbXref "PMID:18430230") obo:IAO_0000115 obo:CL_0005021 "Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics.")
AnnotationAssertion(terms:contributor obo:CL_0005021 <https://orcid.org/0000-0002-2244-7917>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0005021 "2012-01-12T05:01:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0005021 "mesenchymal lymphangioblast")
SubClassOf(obo:CL_0005021 obo:CL_0000134)
SubClassOf(obo:CL_0005021 obo:CL_0005020)

# Class: obo:CL_0005022 (vascular lymphangioblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005022 "Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_0005022 <https://orcid.org/0000-0002-2244-7917>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0005022 "2012-01-12T05:21:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0005022 "parachordal lymphangioblast")
AnnotationAssertion(rdfs:label obo:CL_0005022 "vascular lymphangioblast")
EquivalentClasses(obo:CL_0005022 ObjectIntersectionOf(obo:CL_0005020 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001638)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0005022 obo:CL_0005020)

# Class: obo:CL_0005023 (branchiomotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFIN:CVS") obo:IAO_0000115 obo:CL_0005023 "Cranial motor neuron which innervates muscles derived from the branchial (pharyngeal) arches.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0005023 "PMID:14699587")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005023 "branchi motor neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005023 "special visceral motor neuron")
AnnotationAssertion(rdfs:label obo:CL_0005023 "branchiomotor neuron"@en)
EquivalentClasses(obo:CL_0005023 ObjectIntersectionOf(obo:CL_0015000 ObjectSomeValuesFrom(obo:RO_0002130 obo:UBERON_0004164)))

# Class: obo:CL_0005024 (somatomotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFIN:CVS") obo:IAO_0000115 obo:CL_0005024 "A motor neuron that innervates a skeletal muscle.  These motor neurons are all excitatory and cholinergic.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005024 "somatic motor neuron")
AnnotationAssertion(rdfs:label obo:CL_0005024 "somatomotor neuron"@en)
EquivalentClasses(obo:CL_0005024 ObjectIntersectionOf(obo:CL_0000100 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008002)))
SubClassOf(obo:CL_0005024 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055))

# Class: obo:CL_0005025 (visceromotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFIN:CVS") obo:IAO_0000115 obo:CL_0005025 "A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005025 "general visceral motor neuron")
AnnotationAssertion(rdfs:comment obo:CL_0005025 "Note that these neurons do not synapse directly onto muscles")
AnnotationAssertion(rdfs:label obo:CL_0005025 "visceromotor neuron"@en)
SubClassOf(obo:CL_0005025 obo:CL_0000100)
SubClassOf(obo:CL_0005025 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0011102))

# Class: obo:CL_0005026 (hepatoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CVS") Annotation(oboInOwl:hasDbXref "PMID:18356246") Annotation(oboInOwl:hasDbXref "PMID:20483998") Annotation(oboInOwl:hasDbXref "PMID:26798363") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-1940-6740") obo:IAO_0000115 obo:CL_0005026 "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation.")
AnnotationAssertion(rdfs:label obo:CL_0005026 "hepatoblast"@en)
AnnotationAssertion(rdfs:seeAlso obo:CL_0005026 "https://github.com/obophenotype/cell-ontology/issues/800")
SubClassOf(obo:CL_0005026 obo:CL_0000048)

# Class: obo:CL_0007000 (preameloblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "PMCID:PMC2737325") obo:IAO_0000115 obo:CL_0007000 "Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins.")
AnnotationAssertion(terms:contributor obo:CL_0007000 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007000 "2012-06-15T01:27:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0007000 "unsure of neural crest contribution. In VSAO we have develops_from CL:0000008")
AnnotationAssertion(rdfs:label obo:CL_0007000 "preameloblast")
SubClassOf(obo:CL_0007000 obo:CL_0011026)
SubClassOf(obo:CL_0007000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0007000 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002077))
SubClassOf(obo:CL_0007000 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001763))

# Class: obo:CL_0007001 (skeletogenic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007001 "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized).")
AnnotationAssertion(terms:contributor obo:CL_0007001 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007001 "2012-06-15T02:51:27Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") oboInOwl:hasExactSynonym obo:CL_0007001 "scleroblast")
AnnotationAssertion(rdfs:comment obo:CL_0007001 "Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)")
AnnotationAssertion(rdfs:label obo:CL_0007001 "skeletogenic cell")
SubClassOf(obo:CL_0007001 obo:CL_0000000)

# Class: obo:CL_0007002 (precementoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007002 "Skeletogenic cell that has the potential to develop into a cementoblast.")
AnnotationAssertion(terms:contributor obo:CL_0007002 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007002 "2012-06-15T04:37:13Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007002 "precementoblast")
SubClassOf(obo:CL_0007002 obo:CL_0011026)
SubClassOf(obo:CL_0007002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))

# Class: obo:CL_0007003 (preodontoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007003 "Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell.")
AnnotationAssertion(terms:contributor obo:CL_0007003 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007003 "2012-06-15T05:15:11Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007003 "preodontoblast")
SubClassOf(obo:CL_0007003 obo:CL_0011026)
SubClassOf(obo:CL_0007003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005176))
SubClassOf(obo:CL_0007003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008))

# Class: obo:CL_0007004 (premigratory neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "UBERONREF:0000002") obo:IAO_0000115 obo:CL_0007004 "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells.")
AnnotationAssertion(terms:contributor obo:CL_0007004 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007004 "2012-06-27T08:27:35Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007004 "premigratory neural crest cell")
SubClassOf(obo:CL_0007004 obo:CL_0011012)
SubClassOf(obo:CL_0007004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002342))
SubClassOf(obo:CL_0007004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000133))

# Class: obo:CL_0007005 (notochordal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007005 "Cell that is part of the notochord.")
AnnotationAssertion(terms:contributor obo:CL_0007005 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007005 "2012-06-27T08:47:31Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0007005 "NOTE: TO DO, notochord development still needs work.")
AnnotationAssertion(rdfs:label obo:CL_0007005 "notochordal cell")
SubClassOf(obo:CL_0007005 obo:CL_0000000)
SubClassOf(obo:CL_0007005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002328))
SubClassOf(obo:CL_0007005 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0007006))

# Class: obo:CL_0007006 (chordamesodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007006 "Mesodermal cell that is axially located and gives rise to the cells of the notochord.")
AnnotationAssertion(terms:contributor obo:CL_0007006 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007006 "2012-06-27T08:52:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007006 "axial mesodermal cell")
AnnotationAssertion(rdfs:label obo:CL_0007006 "chordamesodermal cell")
SubClassOf(obo:CL_0007006 obo:CL_0000222)
SubClassOf(obo:CL_0007006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004880))

# Class: obo:CL_0007007 (notochordal sheath cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:MAH") obo:IAO_0000115 obo:CL_0007007 "Notochordal cell that is part of the outer epithelium of the notochord and surrounds the vacuolated notochord cells.")
AnnotationAssertion(terms:contributor obo:CL_0007007 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007007 "2012-06-27T09:26:37Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007007 "notochordal sheath cell")
SubClassOf(obo:CL_0007007 obo:CL_0007005)

# Class: obo:CL_0007008 (notochordal vacuole cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:MAH") obo:IAO_0000115 obo:CL_0007008 "Notochordal cell that is inner portion of the notochord and becomes vacuolated as development proceeds.")
AnnotationAssertion(terms:contributor obo:CL_0007008 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007008 "2012-06-27T09:29:30Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") oboInOwl:hasExactSynonym obo:CL_0007008 "chordablast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14574572") oboInOwl:hasExactSynonym obo:CL_0007008 "chordoblast")
AnnotationAssertion(rdfs:label obo:CL_0007008 "notochordal vacuole cell")
SubClassOf(obo:CL_0007008 obo:CL_0007005)

# Class: obo:CL_0007009 (prechondroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007009 "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells.")
AnnotationAssertion(terms:contributor obo:CL_0007009 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007009 "2012-06-27T10:44:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007009 "prechondroblast")
SubClassOf(obo:CL_0007009 obo:CL_0011026)

# Class: obo:CL_0007010 (preosteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007010 "Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells.")
AnnotationAssertion(terms:contributor obo:CL_0007010 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007010 "2012-06-27T10:57:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007010 "osteoprogenitor cell")
AnnotationAssertion(rdfs:label obo:CL_0007010 "preosteoblast")
SubClassOf(obo:CL_0007010 obo:CL_0011026)
SubClassOf(obo:CL_0007010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008883))
SubClassOf(obo:CL_0007010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000222))
SubClassOf(obo:CL_0007010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))

# Class: obo:CL_0007011 (enteric neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:MAH") obo:IAO_0000115 obo:CL_0007011 "Neuron that is part of the enteric nervous system.")
AnnotationAssertion(terms:contributor obo:CL_0007011 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007011 "2012-06-28T08:20:31Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0007011 "enteric neuron")
EquivalentClasses(obo:CL_0007011 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002005)))
SubClassOf(obo:CL_0007011 obo:CL_0000540)
SubClassOf(obo:CL_0007011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002005))
SubClassOf(obo:CL_0007011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002607))

# Class: obo:CL_0007012 (non-terminally differentiated odontoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") Annotation(oboInOwl:hasDbXref "PSPUB:0000170") obo:IAO_0000115 obo:CL_0007012 "Odontoblast that non-terminally differentiated, located in the odontogenic papilla and dentine tissue, and transforms from a odontoblast cell.")
AnnotationAssertion(rdfs:label obo:CL_0007012 "non-terminally differentiated odontoblast")
SubClassOf(obo:CL_0007012 obo:CL_0000060)
SubClassOf(obo:CL_0007012 obo:CL_0011026)

# Class: obo:CL_0007013 (terminally differentiated odontoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000034") obo:IAO_0000115 obo:CL_0007013 "Odontoblast that is terminally differentiated and derived from an odontogenic papilla and associated with dentine.")
AnnotationAssertion(rdfs:label obo:CL_0007013 "terminally differentiated odontoblast")
SubClassOf(obo:CL_0007013 obo:CL_0000060)

# Class: obo:CL_0007014 (obsolete cell line cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0007014 "OBSOLETE: A cultured cell that has been passaged at least one time in culture.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0007014 obo:CLO_0000001)
AnnotationAssertion(terms:contributor obo:CL_0007014 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007014 "2012-11-28T11:54:59Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007014 "passaged cultured cell")
AnnotationAssertion(rdfs:comment obo:CL_0007014 "Obsoleted in July 2013 and replaced by the CLO 'cell line cell' class, as a result of CLO-OBI-CL alignment efforts.

Covers cells actively being cultured or stored in a quiescent state for future use.")
AnnotationAssertion(rdfs:label obo:CL_0007014 "obsolete cell line cell")
AnnotationAssertion(owl:deprecated obo:CL_0007014 "true"^^xsd:boolean)

# Class: obo:CL_0007015 (obsolete mortal cell line cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ReO:mhb") obo:IAO_0000115 obo:CL_0007015 "OBSOLETE: A cell line cell that is expected to be capable of replicating a limited number of times in culture before undergoing senescence. Mortal cell line cells cannot be propagated indefinitely (as immortal cell line cells can).")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0007015 obo:CLO_0000018)
AnnotationAssertion(terms:contributor obo:CL_0007015 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007015 "2012-11-28T11:56:20Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007015 "finite cell line cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0007015 "primary cell line cell")
AnnotationAssertion(rdfs:comment obo:CL_0007015 "Obsoleted in July 2013 and replaced by the CLO 'mortal cell line cell' class, as a result of CLO-OBI-CL alignment efforts.

Covers cells actively being cultured or stored in a quiescent state for future use.")
AnnotationAssertion(rdfs:label obo:CL_0007015 "obsolete mortal cell line cell")
AnnotationAssertion(owl:deprecated obo:CL_0007015 "true"^^xsd:boolean)

# Class: obo:CL_0007016 (adaxial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8951054") obo:IAO_0000115 obo:CL_0007016 "Muscle precursor cell that is adjacent to the notochord and part of the presomitic mesoderm.")
AnnotationAssertion(terms:contributor obo:CL_0007016 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0007016 "2012-12-30T12:43:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0007016 "In teleosts, adaxial cells give rise to slow muscle myoblasts.")
AnnotationAssertion(rdfs:label obo:CL_0007016 "adaxial cell")
SubClassOf(obo:CL_0007016 obo:CL_0000680)
SubClassOf(obo:CL_0007016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003059))

# Class: obo:CL_0007017 (Stiftchenzellen)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1087183") obo:IAO_0000115 obo:CL_0007017 "An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis.")
AnnotationAssertion(terms:contributor obo:CL_0007017 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(rdfs:comment obo:CL_0007017 "Taxon specificity not yet fully known, but are known in anuran larvae but not in adults.")
AnnotationAssertion(rdfs:label obo:CL_0007017 "Stiftchenzellen")
SubClassOf(obo:CL_0007017 obo:CL_0000206)
SubClassOf(obo:CL_0007017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))
SubClassOf(obo:CL_0007017 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))

# Class: obo:CL_0007018 (epidermal ciliary cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMCID:PMC3046089") obo:IAO_0000115 obo:CL_0007018 "Ciliated cell of the embryonic epidermis and functions in embryonic movements.")
AnnotationAssertion(terms:contributor obo:CL_0007018 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(rdfs:comment obo:CL_0007018 "Taxon specificity not clear -present in embryonic anurans.")
AnnotationAssertion(rdfs:label obo:CL_0007018 "epidermal ciliary cell"@en)
SubClassOf(obo:CL_0007018 obo:CL_0002321)
SubClassOf(obo:CL_0007018 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))
SubClassOf(obo:CL_0007018 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929))

# Class: obo:CL_0007019 (epidermal mucus secreting cell)

AnnotationAssertion(terms:contributor obo:CL_0007019 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(rdfs:comment obo:CL_0007019 "taxon specificity not clear. Appears in early larval stages of anurans and persists after metamorphosis.")
AnnotationAssertion(rdfs:label obo:CL_0007019 "epidermal mucus secreting cell"@en)
SubClassOf(obo:CL_0007019 obo:CL_0000319)

# Class: obo:CL_0007020 (bottle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3197630") obo:IAO_0000115 obo:CL_0007020 "Characteristic early embryonic cell with a bottle or flask shape that is first to migrate inwards at the blastopore during gastrulation in amphibians.")
AnnotationAssertion(terms:contributor obo:CL_0007020 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(rdfs:label obo:CL_0007020 "bottle cell"@en)
SubClassOf(obo:CL_0007020 obo:CL_0000007)

# Class: obo:CL_0007021 (alarm substance cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN-10:0412429403") obo:IAO_0000115 obo:CL_0007021 "Secretory cell that produces a chemical mixture that triggers antipredator behavior. The substance is released only upon disruption of the epidermis. [Behavior of teleost fishes, second edition, edited by Pitcher, 1992]")
AnnotationAssertion(terms:contributor obo:CL_0007021 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007021 "alarm substance secreting cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://github.com/obophenotype/cell-ontology/issues/583") oboInOwl:hasExactSynonym obo:CL_0007021 "club cell (zebrafish)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN-10:0412429403") Annotation(oboInOwl:hasDbXref "https://github.com/obophenotype/cell-ontology/issues/583") oboInOwl:hasRelatedSynonym obo:CL_0007021 "club cell")
AnnotationAssertion(rdfs:label obo:CL_0007021 "alarm substance cell"@en)
SubClassOf(obo:CL_0007021 obo:CL_0000000)
SubClassOf(obo:CL_0007021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))
SubClassOf(obo:CL_0007021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940))

# Class: obo:CL_0007022 (micropylar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18582455") Annotation(oboInOwl:hasDbXref "ZFA:0005239") obo:IAO_0000115 obo:CL_0007022 "A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg.")
AnnotationAssertion(terms:contributor obo:CL_0007022 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0007022 "plug cell")
AnnotationAssertion(rdfs:label obo:CL_0007022 "micropylar cell"@en)
SubClassOf(obo:CL_0007022 obo:CL_0000000)
SubClassOf(obo:CL_0007022 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001305))

# Class: obo:CL_0007023 (flask cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1007/BF00717048") obo:IAO_0000115 obo:CL_0007023 "Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis.")
AnnotationAssertion(terms:contributor obo:CL_0007023 <https://orcid.org/0000-0001-9114-8737>)
AnnotationAssertion(rdfs:label obo:CL_0007023 "flask cell"@en)
SubClassOf(obo:CL_0007023 obo:CL_0000000)
SubClassOf(obo:CL_0007023 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))

# Class: obo:CL_0008000 (non-striated muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:DOS") obo:IAO_0000115 obo:CL_0008000 "Any muscle cell in which the fibers are not organised into sarcomeres.")
AnnotationAssertion(rdfs:label obo:CL_0008000 "non-striated muscle cell")
SubClassOf(obo:CL_0008000 obo:CL_0000187)

# Class: obo:CL_0008001 (hematopoietic precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008001 "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.")
AnnotationAssertion(rdfs:label obo:CL_0008001 "hematopoietic precursor cell")
SubClassOf(obo:CL_0008001 obo:CL_0000988)

# Class: obo:CL_0008002 (skeletal muscle fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0323052908") obo:IAO_0000115 obo:CL_0008002 "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008002 "MESH:D018485")
AnnotationAssertion(rdfs:label obo:CL_0008002 "skeletal muscle fiber"@en)
EquivalentClasses(obo:CL_0008002 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478)))
SubClassOf(obo:CL_0008002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000515))

# Class: obo:CL_0008003 (somatic muscle myotube)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22274696") Annotation(oboInOwl:hasDbXref "PMID:8720463") obo:IAO_0000115 obo:CL_0008003 "A myotube that is part of some somatic muscle.  Examples include arthropod somatic muscle cells.")
AnnotationAssertion(rdfs:label obo:CL_0008003 "somatic muscle myotube")
EquivalentClasses(obo:CL_0008003 ObjectIntersectionOf(obo:CL_0008004 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478)))

# Class: obo:CL_0008004 (somatic muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008004 "A muscle cell that is part of some somatic muscle.")
AnnotationAssertion(rdfs:label obo:CL_0008004 "somatic muscle cell"@en)
SubClassOf(obo:CL_0008004 obo:CL_0000187)

# Class: obo:CL_0008005 (obliquely striated somatic muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8720463") Annotation(oboInOwl:hasDbXref "doi:10.3908/wormatlas.1.7") obo:IAO_0000115 obo:CL_0008005 "A somatic muscle cell that is obliquely striated and mononucleated. Examples include the somatic muscles of nematodes.")
AnnotationAssertion(rdfs:label obo:CL_0008005 "obliquely striated somatic muscle cell")
EquivalentClasses(obo:CL_0008005 ObjectIntersectionOf(obo:CL_0008004 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002479)))
SubClassOf(obo:CL_0008005 obo:CL_0008004)

# Class: obo:CL_0008006 (muscle founder cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22274696") obo:IAO_0000115 obo:CL_0008006 "A myoblast that detemines the properties (size, shape and attachment to the epidermis) of a `somatic muscle myotube` (CL:0008003) .  It develops into a somatic muscle myotube via fusion with `fusion component myoblasts` (CL:0000621).")
AnnotationAssertion(rdfs:label obo:CL_0008006 "muscle founder cell"@en)
SubClassOf(obo:CL_0008006 obo:CL_0000056)
SubClassOf(obo:CL_0008006 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008003))

# Class: obo:CL_0008007 (visceral muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008007 "A muscle cell that is part of some visceral muscle.")
AnnotationAssertion(rdfs:label obo:CL_0008007 "visceral muscle cell"@en)
EquivalentClasses(obo:CL_0008007 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600004)))

# Class: obo:CL_0008008 (striated visceral muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008008 "A visceral muscle cell that is striated.  Examples include the visceral muscle cells of arhtropods.")
AnnotationAssertion(rdfs:label obo:CL_0008008 "striated visceral muscle cell"@en)
EquivalentClasses(obo:CL_0008008 ObjectIntersectionOf(obo:CL_0008007 ObjectIntersectionOf(ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001410))))

# Class: obo:CL_0008009 (transversely striated visceral muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008009 "A visceral muscle that is transversely striated.  Examples include the visceral muscle cells of arthropods.")
AnnotationAssertion(rdfs:label obo:CL_0008009 "transversely striated visceral muscle cell"@en)
EquivalentClasses(obo:CL_0008009 ObjectIntersectionOf(obo:CL_0008007 ObjectIntersectionOf(ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030017) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002478))))

# Class: obo:CL_0008010 (cranial somatomotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14699587") obo:IAO_0000115 obo:CL_0008010 "A cranial motor neuron whose soma is located in the midbrain andor hindbrain and which innervates the skeletal muscles of the eye or tongue.")
AnnotationAssertion(rdfs:label obo:CL_0008010 "cranial somatomotor neuron")
EquivalentClasses(obo:CL_0008010 ObjectIntersectionOf(obo:CL_0015000 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008002)))

# Class: obo:CL_0008011 (skeletal muscle satellite stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0008011 "A skeletal muscle satellite cell that divides by stem cell division.  A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast.")
AnnotationAssertion(rdfs:label obo:CL_0008011 "skeletal muscle satellite stem cell")
EquivalentClasses(obo:CL_0008011 ObjectIntersectionOf(obo:CL_0000594 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001400) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145)))
DisjointClasses(obo:CL_0008011 obo:CL_0008020)

# Class: obo:CL_0008012 (quiescent skeletal muscle satellite cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21849021") Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0008012 "A skeletal muscle satellite cell that is mitotically quiescent.  These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage.")
AnnotationAssertion(rdfs:label obo:CL_0008012 "quiescent skeletal muscle satellite cell")
SubClassOf(obo:CL_0008012 obo:CL_0000594)

# Class: obo:CL_0008013 (cranial visceromotor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14699587") obo:IAO_0000115 obo:CL_0008013 "A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head.")
AnnotationAssertion(rdfs:label obo:CL_0008013 "cranial visceromotor neuron"@en)
EquivalentClasses(obo:CL_0008013 ObjectIntersectionOf(obo:CL_0005025 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002028)))
SubClassOf(obo:CL_0008013 obo:CL_0015000)

# Class: obo:CL_0008014 (obsolete excitatory motor neuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008014 "A motor neuron that is capable of directly inducing muscle contraction.")
AnnotationAssertion(rdfs:comment obo:CL_0008014 "In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0008014 "obsolete excitatory motor neuron"@en)
AnnotationAssertion(owl:deprecated obo:CL_0008014 "true"^^xsd:boolean)

# Class: obo:CL_0008015 (inhibitory motor neuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008015 "A motor neuron that is capable of directly inhibiting muscle contraction.")
AnnotationAssertion(obo:RO_0002161 obo:CL_0008015 obo:NCBITaxon_7742)
AnnotationAssertion(rdfs:comment obo:CL_0008015 "In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates.")
AnnotationAssertion(rdfs:label obo:CL_0008015 "inhibitory motor neuron"@en)
SubClassOf(obo:CL_0008015 obo:CL_0000100)

# Class: obo:CL_0008016 (activated skeletal muscle satellite cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21849021") Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0008016 "A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage.")
AnnotationAssertion(rdfs:label obo:CL_0008016 "activated skeletal muscle satellite cell")
SubClassOf(obo:CL_0008016 obo:CL_0000594)
SubClassOf(Annotation(rdfs:comment "More accurately - transformation_of ?") obo:CL_0008016 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0008012))

# Class: obo:CL_0008017 (adult skeletal muscle myoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0008017 "A skeletal muscle myoblast that is part of a skeletal mucle.  These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23303905") oboInOwl:hasBroadSynonym obo:CL_0008017 "myogenic precursor cell")
AnnotationAssertion(rdfs:comment obo:CL_0008017 "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.")
AnnotationAssertion(rdfs:label obo:CL_0008017 "adult skeletal muscle myoblast")
EquivalentClasses(obo:CL_0008017 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134) ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008002)))

# Class: obo:CL_0008018 (somatic muscle myoblast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008018 "A myoblast that is commited to developing into a somatic muscle.")
AnnotationAssertion(rdfs:label obo:CL_0008018 "somatic muscle myoblast")
EquivalentClasses(obo:CL_0008018 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008003)))

# Class: obo:CL_0008019 (mesenchymal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008019 "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008019 "mesenchyme cell")
AnnotationAssertion(rdfs:label obo:CL_0008019 "mesenchymal cell")
SubClassOf(obo:CL_0008019 obo:CL_0000000)
SubClassOf(obo:CL_0008019 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003104))
SubClassOf(obo:CL_0008019 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0016477))

# Class: obo:CL_0008020 (skeletal muscle satellite myogenic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") Annotation(oboInOwl:hasDbXref "PMID:23303905") obo:IAO_0000115 obo:CL_0008020 "A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts.")
AnnotationAssertion(rdfs:label obo:CL_0008020 "skeletal muscle satellite myogenic cell")
SubClassOf(obo:CL_0008020 obo:CL_0000594)
SubClassOf(obo:CL_0008020 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0008017))

# Class: obo:CL_0008021 (anterior lateral line ganglion neuron)

AnnotationAssertion(rdfs:label obo:CL_0008021 "anterior lateral line ganglion neuron")
EquivalentClasses(obo:CL_0008021 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_2001391)))

# Class: obo:CL_0008022 (endocardial cushion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18816864") obo:IAO_0000115 obo:CL_0008022 "A mesenchymal cell of the endocardial cushion.   These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves.")
AnnotationAssertion(rdfs:label obo:CL_0008022 "endocardial cushion cell")
EquivalentClasses(obo:CL_0008022 ObjectIntersectionOf(obo:CL_0000569 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002062)))

# Class: obo:CL_0008023 (obsolete cardiac fibroblast)

AnnotationAssertion(obo:IAO_0100001 obo:CL_0008023 obo:CL_0002548)
AnnotationAssertion(rdfs:comment obo:CL_0008023 "Duplicate term.")
AnnotationAssertion(rdfs:label obo:CL_0008023 "obsolete cardiac fibroblast")
AnnotationAssertion(owl:deprecated obo:CL_0008023 "true"^^xsd:boolean)

# Class: obo:CL_0008024 (pancreatic endocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008024 "An endocrine cell that is part of the pancreas.")
AnnotationAssertion(rdfs:label obo:CL_0008024 "pancreatic endocrine cell")
EquivalentClasses(obo:CL_0008024 ObjectIntersectionOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))
SubClassOf(obo:CL_0008024 obo:CL_0000163)

# Class: obo:CL_0008025 (noradrenergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008025 "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter.")
AnnotationAssertion(rdfs:label obo:CL_0008025 "noradrenergic neuron")
EquivalentClasses(obo:CL_0008025 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061533)))

# Class: obo:CL_0008026 (open tracheal system tracheocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0008026 "An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects.")
AnnotationAssertion(rdfs:label obo:CL_0008026 "open tracheal system tracheocyte")
EquivalentClasses(obo:CL_0008026 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003127)))

# Class: obo:CL_0008027 (rod bipolar cell (sensu Mus))

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008027 "A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells.  These neurons have axons that arborize and synapse to targets in inner plexiform layers 4 and 5 and depolarize in response to light.")
AnnotationAssertion(terms:contributor obo:CL_0008027 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008027 "2017-06-29T11:05:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008027 "rod bipolar cell (sensu Mus)")
SubClassOf(obo:CL_0008027 obo:CL_0000751)

# Class: obo:CL_0008028 (visual system neuron)

AnnotationAssertion(terms:contributor obo:CL_0008028 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008028 "2017-07-09T19:12:36Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008028 "visual system neuron")
EquivalentClasses(obo:CL_0008028 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0007601)))

# Class: obo:CL_0008029 (obsolete inhibitory neuron)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0008029 <https://github.com/obophenotype/cell-ontology/issues/1540>)
AnnotationAssertion(terms:contributor obo:CL_0008029 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008029 "2017-07-12T11:10:52Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0008029 "Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution.")
AnnotationAssertion(rdfs:label obo:CL_0008029 "obsolete inhibitory neuron")
AnnotationAssertion(owl:deprecated obo:CL_0008029 "true"^^xsd:boolean)

# Class: obo:CL_0008030 (obsolete excitatory neuron)

AnnotationAssertion(obo:IAO_0000233 obo:CL_0008030 <https://github.com/obophenotype/cell-ontology/issues/1540>)
AnnotationAssertion(terms:contributor obo:CL_0008030 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008030 "2017-07-12T11:11:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0008030 "Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution.")
AnnotationAssertion(rdfs:label obo:CL_0008030 "obsolete excitatory neuron")
AnnotationAssertion(owl:deprecated obo:CL_0008030 "true"^^xsd:boolean)

# Class: obo:CL_0008031 (cortical interneuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0008031 "An interneuron that has its soma located in the cerebral cortex.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008031 "cerebral cortex interneuron")
AnnotationAssertion(rdfs:label obo:CL_0008031 "cortical interneuron"@en)
EquivalentClasses(obo:CL_0008031 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_0008032 (rosehip neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41593-018-0205-2") obo:IAO_0000115 obo:CL_0008032 "A GABAergic interneuron in human cortical layer 1 that has large rosehip-shaped axonal boutons and compact arborization.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41593-018-0205-2") rdfs:comment obo:CL_0008032 "A rosehip cell has been shown to have an immunohistochemical profile GAD1+CCK+, CNR1–SST–CALB2–PVALB– that matches a single transcriptomically defined cell type whose specific molecular marker signature is not seen in mouse cortex.")
AnnotationAssertion(rdfs:label obo:CL_0008032 "rosehip neuron"@en)
SubClassOf(obo:CL_0008032 obo:CL_0000099)
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005390))
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000005110))
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007785))
SubClassOf(obo:CL_0008032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000011467))

# Class: obo:CL_0008033 (decidual pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") obo:IAO_0000115 obo:CL_0008033 "A pericyte of the decidual vasculature.")
AnnotationAssertion(terms:contributor obo:CL_0008033 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008033 "2020-02-29T11:45:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008033 "decidual perivascular cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0008033 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0008033 "decidual pericyte"@en)
EquivalentClasses(obo:CL_0008033 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002450)))
SubClassOf(obo:CL_0008033 obo:CL_0000669)

# Class: obo:CL_0008034 (mural cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wiki:Mural_cell&oldid=930603194") obo:IAO_0000115 obo:CL_0008034 "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.")
AnnotationAssertion(terms:contributor obo:CL_0008034 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008034 "2020-02-29T17:33:55Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0008034 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0008034 "mural cell"@en)
SubClassOf(obo:CL_0008034 obo:CL_4033054)

# Class: obo:CL_0008035 (microcirculation associated smooth muscle cell)

AnnotationAssertion(terms:contributor obo:CL_0008035 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008035 "2020-02-29T17:37:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008035 "microcirculation associated smooth muscle cell"@en)
EquivalentClasses(obo:CL_0008035 ObjectIntersectionOf(obo:CL_0000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010523)))
SubClassOf(obo:CL_0008035 obo:CL_0008034)

# Class: obo:CL_0008036 (extravillous trophoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31049600") obo:IAO_0000115 obo:CL_0008036 "A trophoblast cell that is not part of a placental villous.")
AnnotationAssertion(terms:contributor obo:CL_0008036 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008036 "2020-03-02T08:45:06Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31049600") oboInOwl:hasExactSynonym obo:CL_0008036 "EVT")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008036 "extravillous cytotrophloblast")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0008036 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0008036 "extravillous trophoblast"@en)
SubClassOf(obo:CL_0008036 obo:CL_0000351)

# Class: obo:CL_0008037 (gamma motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1093/acprof:oso/9780195159561.001.1") Annotation(oboInOwl:hasDbXref "WikipediaVersion:Gamma_motor_neuron&oldid=906640465") obo:IAO_0000115 obo:CL_0008037 "A lower motor neuron that innervates only intrafusal muscle fibers. Unlike the alpha motor neurons, gamma motor neurons do not directly adjust the lengthening or shortening of muscles but function in adjusting the sensitivity of muscle spindles and in keeping muscle spindles taut, thereby allowing the continued firing of alpha neurons.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008037 "FMA:83660")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008037 "MESH:D009047")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008037 "SAO:143800623")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Gamma_motor_neuron&oldid=1037462173") oboInOwl:hasExactSynonym obo:CL_0008037 "fusimotor neuron")
AnnotationAssertion(rdfs:label obo:CL_0008037 "gamma motor neuron"@en)
SubClassOf(obo:CL_0008037 obo:CL_0008039)
SubClassOf(obo:CL_0008037 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008047))

# Class: obo:CL_0008038 (alpha motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-12-801238-3.05364-2") Annotation(oboInOwl:hasDbXref "Wikipedia:Alpha_motor_neuron&oldid=957148643") obo:IAO_0000115 obo:CL_0008038 "A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS.")
AnnotationAssertion(terms:contributor obo:CL_0008038 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008038 "2020-09-23T20:16:26Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008038 "alpha motoneuron")
AnnotationAssertion(rdfs:label obo:CL_0008038 "alpha motor neuron"@en)
SubClassOf(obo:CL_0008038 obo:CL_0008039)
SubClassOf(obo:CL_0008038 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008046))

# Class: obo:CL_0008039 (lower motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Lower_motor_neuron&oldid=952547294") obo:IAO_0000115 obo:CL_0008039 "The motor neurons of vertebrates that directly innervate skeletal muscles. They receive input from upper motor neurons.")
AnnotationAssertion(terms:contributor obo:CL_0008039 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008039 "2020-09-23T20:22:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008039 "FMA:84632")
AnnotationAssertion(rdfs:label obo:CL_0008039 "lower motor neuron"@en)
SubClassOf(obo:CL_0008039 obo:CL_0000100)
SubClassOf(obo:CL_0008039 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008002))
SubClassOf(obo:CL_0008039 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742))

# Class: obo:CL_0008040 (squamous endothelial cell of venule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0008040 "An endothelial cell of the venule that is squamous shaped. This is in contrast to the cubodial shape of high endothelial venule cells.")
AnnotationAssertion(terms:contributor obo:CL_0008040 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008040 "2024-07-03T19:52:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008040 "squamous endothelial cell of venule"@en)
SubClassOf(obo:CL_0008040 obo:CL_0002139)
SubClassOf(obo:CL_0008040 obo:CL_0002653)
SubClassOf(obo:CL_0008040 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001979))

# Class: obo:CL_0008041 (mesothelial cell of intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-7073-9172") obo:IAO_0000115 obo:CL_0008041 "A mesothelial cell that is part of the intestinal serosa.")
AnnotationAssertion(terms:contributor obo:CL_0008041 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008041 "2025-02-04T18:42:26Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008041 "mesothelial cell of intestine")
EquivalentClasses(obo:CL_0008041 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001243)))

# Class: obo:CL_0008042 (tanycyte of subfornical organ)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") obo:IAO_0000115 obo:CL_0008042 "A tanycyte of the subfornical organ (SFO).  These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SFO, where they form a dense network surrounding these capillaries.")
AnnotationAssertion(terms:contributor obo:CL_0008042 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008042 "2025-03-11T11:43:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") oboInOwl:hasExactSynonym obo:CL_0008042 "tanycyte-like cell of subfornical organ")
AnnotationAssertion(rdfs:label obo:CL_0008042 "tanycyte of subfornical organ")
EquivalentClasses(obo:CL_0008042 ObjectIntersectionOf(obo:CL_0002085 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002219)))

# Class: obo:CL_0008044 (tanycyte of area postrema)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") obo:IAO_0000115 obo:CL_0008044 "A tanycyte of the area postrema (AP).  These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the AP, where they form a dense network surrounding these capillaries.")
AnnotationAssertion(terms:contributor obo:CL_0008044 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008044 "2025-03-11T12:09:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") oboInOwl:hasExactSynonym obo:CL_0008044 "tanycyte-like cell of area postrema")
AnnotationAssertion(rdfs:label obo:CL_0008044 "tanycyte of area postrema")
EquivalentClasses(obo:CL_0008044 ObjectIntersectionOf(obo:CL_0002085 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002162)))

# Class: obo:CL_0008045 (tanycyte of subcommissural organ)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") obo:IAO_0000115 obo:CL_0008045 "A tanycyte of the subcommisural organ (SCO).  These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SCO, where they form a dense network surrounding these capillaries.")
AnnotationAssertion(terms:contributor obo:CL_0008045 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008045 "2025-03-11T12:09:34Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") oboInOwl:hasExactSynonym obo:CL_0008045 "tanycyte-like cell of subcommissural organ")
AnnotationAssertion(rdfs:label obo:CL_0008045 "tanycyte of subcommissural organ")
EquivalentClasses(obo:CL_0008045 ObjectIntersectionOf(obo:CL_0002085 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002139)))

# Class: obo:CL_0008046 (extrafusal muscle fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-443-10321-6.00004-7") Annotation(oboInOwl:hasDbXref "Wikipedia:Extrafusal_muscle_fiber&oldid=978415293") obo:IAO_0000115 obo:CL_0008046 "A skeletal muscle fiber that is innervated by alpha motor neuron and generates tension by contracting, thereby allowing for skeletal movement. These fibers make up the large mass of skeletal muscle tissue and are attached to bones by tendons.")
AnnotationAssertion(terms:contributor obo:CL_0008046 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008046 "2020-09-26T21:06:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008046 "TH:H3.03.00.0.00007")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008046 "myofibra extrafusalis")
AnnotationAssertion(rdfs:label obo:CL_0008046 "extrafusal muscle fiber"@en)
SubClassOf(obo:CL_0008046 obo:CL_0008002)
SubClassOf(obo:CL_0008046 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0008038))
DisjointClasses(obo:CL_0008046 obo:CL_0008047)

# Class: obo:CL_0008047 (intrafusal muscle fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-443-10321-6.00004-7") Annotation(oboInOwl:hasDbXref "Wikipedia:Intrafusal_muscle_fiber&oldid=937508784") obo:IAO_0000115 obo:CL_0008047 "A skeletal muscle fiber that is part of a muscle spindle. These are specialized muscle fibers that serve as proprioceptors, detecting the amount and rate of change in length of a muscle. They are innervated by both sensory neurons and motor neurons (gamma and beta motorneurons, collectively referred to as fusimotor neurons).")
AnnotationAssertion(terms:contributor obo:CL_0008047 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008047 "2020-09-26T21:07:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0008047 "TH:H3.03.00.0.00012")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008047 "myofibra intrafusalis")
AnnotationAssertion(rdfs:label obo:CL_0008047 "intrafusal muscle fiber"@en)
EquivalentClasses(obo:CL_0008047 ObjectIntersectionOf(obo:CL_0008002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003718)))

# Class: obo:CL_0008048 (upper motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Upper_motor_neuron&oldid=943248837") obo:IAO_0000115 obo:CL_0008048 "A glutamatergic motor neuron with a soma in the brainstem or cerebral cortex.  They do not synapse directly to muscles but rather to lower motor neurons, which do.  They are the main controllers of voluntary movement.")
AnnotationAssertion(terms:contributor obo:CL_0008048 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008048 "2020-09-28T09:41:48Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008048 "upper motor neuron"@en)
SubClassOf(obo:CL_0008048 obo:CL_0000100)
SubClassOf(obo:CL_0008048 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008039))
SubClassOf(obo:CL_0008048 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_33208))
SubClassOf(obo:CL_0008048 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535))

# Class: obo:CL_0008049 (Betz cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") Annotation(oboInOwl:hasDbXref "Wikipedia:Betz_cell&oldid=977472330") obo:IAO_0000115 obo:CL_0008049 "A giant pyramidal neuron with a soma in layer Vb of the primary motor cortex that sends its axons down the spinal cord via the corticospinal tract, either synapsing directly with alpha motor neurons, or targeting interneurons in the spinal cord. In humans, Betz cells are the largest known in the central nervous system.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0008049 obo:NCBITaxon_9443)
AnnotationAssertion(terms:contributor obo:CL_0008049 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0008049 "2020-09-28T09:52:58Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0008049 "pyramidal cell of Betz")
AnnotationAssertion(rdfs:label obo:CL_0008049 "Betz cell"@en)
AnnotationAssertion(foaf:depiction obo:CL_0008049 "https://en.wikipedia.org/w/index.php?title=Betz_cell&oldid=977472330#/media/File:GolgiStainedPyramidalCell.jpg")
SubClassOf(obo:CL_0008049 obo:CL_4023041)
SubClassOf(obo:CL_0008049 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070017))
SubClassOf(obo:CL_0008049 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0022315))
SubClassOf(obo:CL_0008049 ObjectSomeValuesFrom(obo:RO_0002101 obo:UBERON_0002707))

# Class: obo:CL_0008053 (circumventricular organ capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26578857") Annotation(oboInOwl:hasDbXref "PMID:35726097") obo:IAO_0000115 obo:CL_0008053 "A capillary endothelial cell that is part of the circumventricular organs (CVOs), characterized by fenestrations that facilitate selective permeability to molecules, distinguishing it from the non-fenestrated endothelial cells of the blood-brain barrier. This cell is integral to the unique vascular structure of CVOs, which lack a traditional blood-brain barrier. It enables bidirectional exchange of polar molecules between blood and neural tissue, supporting neuroendocrine signaling, fluid balance, and immune responses. It is marked by the expression of PLVAP, a component of the fenestral diaphragm, in both rodents and humans.")
AnnotationAssertion(terms:contributor obo:CL_0008053 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008053 "2025-03-14T12:44:38Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008053 "circumventricular organ capillary endothelial cell")
EquivalentClasses(obo:CL_0008053 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005408)))
SubClassOf(obo:CL_0008053 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_0008055 (respiratory tract secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41591-023-02327-2.") obo:IAO_0000115 obo:CL_0008055 "A secretory epithelial cell of the respiratory tract epithelium.  These cells have an endodermal origin.")
AnnotationAssertion(terms:contributor obo:CL_0008055 "https://orcid.org/0000-0002-7073-9172")
AnnotationAssertion(terms:date obo:CL_0008055 "2025-02-19T16:01:02Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008055 "respiratory tract secretory epithelial cell")
EquivalentClasses(obo:CL_0008055 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802)))

# Class: obo:CL_0008059 (GABA-Gly neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18677503") Annotation(oboInOwl:hasDbXref "PMID:37124720") obo:IAO_0000115 obo:CL_0008059 "A neuron that releases both gamma-aminobutyric acid and glycine as vesicular neurotransmitters.  Examples include types of amacrine cell and types of cerebellar inhibitory neurons.")
AnnotationAssertion(terms:contributor obo:CL_0008059 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008059 "2025-06-19T09:57:55Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008059 "GABA-Gly neuron")
EquivalentClasses(obo:CL_0008059 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537)))

# Class: obo:CL_0008060 (GABA-Glut neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29924991") Annotation(oboInOwl:hasDbXref "PMID:37124720") Annotation(oboInOwl:hasDbXref "PMID:38092916") obo:IAO_0000115 obo:CL_0008060 "A neuron that releases both gamma-aminobutyric acid and glutamate as vesicular neurotransmitters.")
AnnotationAssertion(terms:contributor obo:CL_0008060 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008060 "2025-06-19T10:06:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008060 "GABA-Glut neuron")
EquivalentClasses(obo:CL_0008060 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535)))

# Class: obo:CL_0008061 (GABA-Chol neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29651049") obo:IAO_0000115 obo:CL_0008061 "A neuron that releases both gamma-aminobutyric acid and acetylcholine as vesicular neurotransmitters.  Examples include some types of striatal interneuron.")
AnnotationAssertion(terms:contributor obo:CL_0008061 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_0008061 "2025-06-19T10:13:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0008061 "GABA-Chol neuron")
EquivalentClasses(obo:CL_0008061 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_0009000 (sensory neuron of spinal nerve)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") Annotation(oboInOwl:hasDbXref "GOC:pr") obo:IAO_0000115 obo:CL_0009000 "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009000 "spinal sensory neuron")
AnnotationAssertion(rdfs:label obo:CL_0009000 "sensory neuron of spinal nerve")
EquivalentClasses(obo:CL_0009000 ObjectIntersectionOf(obo:CL_0000101 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001780)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0009000 obo:CL_0000101)

# Class: obo:CL_0009001 (compound eye retinal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0009001 "Any cell in the compound eye, a light sensing organ composed of ommatidia.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009001 "GOC:pr")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009001 "PMID:12021768")
AnnotationAssertion(rdfs:label obo:CL_0009001 "compound eye retinal cell")
EquivalentClasses(obo:CL_0009001 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 ObjectIntersectionOf(obo:UBERON_0005388 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000018)))))

# Class: obo:CL_0009002 (inflammatory cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0009002 "Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009002 "GOC:pr")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009002 "http://en.wikipedia.org/wiki/Inflammatory_response")
AnnotationAssertion(rdfs:label obo:CL_0009002 "inflammatory cell")
SubClassOf(obo:CL_0009002 obo:CL_0000000)
SubClassOf(obo:CL_0009002 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0006954))

# Class: obo:CL_0009003 (larval midgut cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0009003 "Any cell in the midgut (middle subdivision of a digestive tract) of an insect larva.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009003 "GOC:pr")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009003 "http://en.wikipedia.org/wiki/Insect#Midgut")
AnnotationAssertion(rdfs:label obo:CL_0009003 "larval midgut cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009003 "https://github.com/obophenotype/cell-ontology/issues/710")
SubClassOf(obo:CL_0009003 obo:CL_0000000)
SubClassOf(obo:CL_0009003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001555))
SubClassOf(obo:CL_0009003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002548))
SubClassOf(obo:CL_0009003 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_50557))

# Class: obo:CL_0009004 (retinal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") obo:IAO_0000115 obo:CL_0009004 "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009004 "PMID:10702418")
AnnotationAssertion(rdfs:label obo:CL_0009004 "retinal cell")
EquivalentClasses(obo:CL_0009004 ObjectIntersectionOf(obo:CL_0002319 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005388)))
SubClassOf(obo:CL_0009004 obo:CL_0002319)

# Class: obo:CL_0009005 (salivary gland cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0009005 "Any cell in a salivary gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009005 "GOC:pr")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009005 "http://en.wikipedia.org/wiki/Salivary_gland")
AnnotationAssertion(rdfs:label obo:CL_0009005 "salivary gland cell")
SubClassOf(obo:CL_0009005 obo:CL_0000000)
SubClassOf(obo:CL_0009005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001044))

# Class: obo:CL_0009006 (enteroendocrine cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009006 "An enteroendocrine cell that is located in the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009006 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009006 "small intestine enteroendocrine cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009006 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009006 "enteroendocrine cell of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0009006 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0009006 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(obo:CL_0009006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0009007 (gastrointestinal tract (lamina propria) macrophage of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009007 "A macrophage which is resident in the lamina propria of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009007 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009007 "macrophage of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009007 "small intestine lamina propria resident macrophage")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009007 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009007 "gastrointestinal tract (lamina propria) macrophage of small intestine")
EquivalentClasses(obo:CL_0009007 ObjectIntersectionOf(obo:CL_0000885 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001238)))

# Class: obo:CL_0009008 (gastrointestinal tract (lamina propria) macrophage of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009008 "A macrophage which is resident in the lamina propria of the large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009008 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009008 "macrophage of large intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009008 "large intestine lamina propria resident macrophage")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009008 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009008 "gastrointestinal tract (lamina propria) macrophage of large intestine")
EquivalentClasses(obo:CL_0009008 ObjectIntersectionOf(obo:CL_0000885 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011189)))

# Class: obo:CL_0009009 (paneth cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31753849") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009009 "A paneth cell that is located in the epithelium of the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009009 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009009 "paneth cell of epithelium of large intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009009 "paneth cell of epithelium of colon")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009009 "paneth-like cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009009 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009009 "paneth cell of colon")
EquivalentClasses(obo:CL_0009009 ObjectIntersectionOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))
SubClassOf(obo:CL_0009009 obo:CL_0002253)

# Class: obo:CL_0009010 (transit amplifying cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24813615") Annotation(oboInOwl:hasDbXref "PMID:28835754") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009010 "Transit-amplifying cells (TACs) are an undifferentiated population in transition between stem cells and differentiated cells.")
AnnotationAssertion(terms:contributor obo:CL_0009010 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009010 "transient amplifying cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30827895") oboInOwl:hasExactSynonym obo:CL_0009010 "transit amplifying progenitor cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009010 "transit-amplifying cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0009010 "TAC")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0009010 "TACs")
AnnotationAssertion(rdfs:label obo:CL_0009010 "transit amplifying cell")
SubClassOf(obo:CL_0009010 obo:CL_0000000)
SubClassOf(obo:CL_0009010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000034))

# Class: obo:CL_0009011 (transit amplifying cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20801415") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009011 "A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells.")
AnnotationAssertion(terms:contributor obo:CL_0009011 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009011 "transit amplifying cell of large intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009011 "colon transit amplifying cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009011 "transient amplifying cell of colon")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009011 "transient amplifying cell of crypt of Lieberkuhn of colon")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009011 "transit amplifying cell of crypt of Lieberkuhn of colon")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009011 "transit-amplifying cell of colon")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009011 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009011 "transit amplifying cell of colon")
EquivalentClasses(obo:CL_0009011 ObjectIntersectionOf(obo:CL_4047017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013485)))
SubClassOf(obo:CL_0009011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002250))

# Class: obo:CL_0009012 (transit amplifying cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20801415") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009012 "A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells.")
AnnotationAssertion(terms:contributor obo:CL_0009012 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009012 "small intestine transit amplifying cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009012 "transient amplifying cell of crypt of Lieberkuhn of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009012 "transient amplifying cell of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009012 "transit amplifying cell of crypt of Lieberkuhn of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009012 "transit-amplifying cell of small intestine")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009012 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009012 "transit amplifying cell of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine , including the crypts of Lieberkhun (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0009012 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0009012 ObjectIntersectionOf(obo:CL_4047017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001241)))
SubClassOf(obo:CL_0009012 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002250))

# Class: obo:CL_0009013 (fetal hepatobiliary progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31350390") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-3163-0115") obo:IAO_0000115 obo:CL_0009013 "A progenitor cell with hepatic and biliary lineage potential, identified in mouse and human, and anatomically restricted to the ductal plate of fetal liver.")
AnnotationAssertion(terms:contributor obo:CL_0009013 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009013 "HHyP cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009013 "fetal hepatobiliary hybrid progenitor cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009013 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0009013 "fetal hepatobiliary progenitor cell")
SubClassOf(obo:CL_0009013 obo:CL_0011026)
SubClassOf(obo:CL_0009013 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410003))
SubClassOf(obo:CL_0009013 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_40674))

# Class: obo:CL_0009014 (Peyer's patch lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23525039") Annotation(oboInOwl:hasDbXref "PMID:9252325") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009014 "A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells.")
AnnotationAssertion(terms:contributor obo:CL_0009014 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009014 "Peyer's patch resident lymphocyte")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0009014 "small intestine Peyer's patch lymphocyte")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009014 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009014 "Peyer's patch lymphocyte")
EquivalentClasses(obo:CL_0009014 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001211)))

# Class: obo:CL_0009015 (Peyer's patch follicular dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24437401") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009015 "A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside.")
AnnotationAssertion(terms:contributor obo:CL_0009015 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009015 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009015 "Peyer's patch follicular dendritic cell")
EquivalentClasses(obo:CL_0009015 ObjectIntersectionOf(obo:CL_0000442 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001211)))

# Class: obo:CL_0009016 (intestinal crypt stem cell of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009016 "An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.")
AnnotationAssertion(terms:contributor obo:CL_0009016 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009016 "crypt stem cell of large intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009016 "stem cell of large intestine crypt of Lieberkuhn")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009016 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009016 "intestinal crypt stem cell of large intestine")
EquivalentClasses(obo:CL_0009016 ObjectIntersectionOf(obo:CL_0002250 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001984)))

# Class: obo:CL_0009017 (intestinal crypt stem cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009017 "An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.")
AnnotationAssertion(terms:contributor obo:CL_0009017 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009017 "crypt stem cell of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009017 "stem cell of small intestine crypt of Lieberkuhn")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009017 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009017 "intestinal crypt stem cell of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0009017 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0009017 ObjectIntersectionOf(obo:CL_0002250 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001241)))

# Class: obo:CL_0009018 (lymphocyte of large intestine lamina propria)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009018 "A lymphocyte that resides in the lamina propria of the large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009018 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009018 "lamina propria lymphocyte of large intestine")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009018 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009018 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009018 "lymphocyte of large intestine lamina propria")
EquivalentClasses(obo:CL_0009018 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011189)))

# Class: obo:CL_0009019 (nephrogenic zone cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29449449") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-3163-0115") obo:IAO_0000115 obo:CL_0009019 "A kidney cortical cell that is part of the nephrogenic zone.")
AnnotationAssertion(terms:contributor obo:CL_0009019 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009019 "cortical nephrogenic niche cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009019 "cortical nephrogenic zone cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009019 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0009019 "nephrogenic zone cell")
EquivalentClasses(obo:CL_0009019 ObjectIntersectionOf(obo:CL_0002681 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009871)))

# Class: obo:CL_0009020 (tuft cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009020 "An intestinal tuft cell that is a part of a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009020 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009020 "appendix tuft cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009020 "tuft cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009020 "tuft cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009020 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009020 "tuft cell of appendix")
EquivalentClasses(obo:CL_0009020 ObjectIntersectionOf(obo:CL_0019032 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009021 (stromal cell of lamina propria of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009021 "A stromal cell found in the lamina propria of the large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009021 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009021 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009021 "stromal cell of lamina propria of large intestine")
EquivalentClasses(obo:CL_0009021 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011189)))

# Class: obo:CL_0009022 (stromal cell of lamina propria of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009022 "A stromal cell found in the lamina propria of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009022 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009022 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009022 "stromal cell of lamina propria of small intestine")
EquivalentClasses(obo:CL_0009022 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001238)))

# Class: obo:CL_0009023 (small intestine Peyer's patch T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009023 "A T cell which resides in the Peyer's patch of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009023 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009023 "T cell of Peyer's patch of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009023 "T cell of small intestine Peyer's patch")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009023 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009023 "small intestine Peyer's patch T cell")
EquivalentClasses(obo:CL_0009023 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003454)))

# Class: obo:CL_0009024 (mesothelial cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009024 "A mesothelial cell that is part of the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009024 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009024 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009024 "mesothelial cell of small intestine")
EquivalentClasses(obo:CL_0009024 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001206)))

# Class: obo:CL_0009025 (mesothelial cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009025 "A mesothelial cell that is part of the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009025 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009025 "mesothelial cell of large intestine")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009025 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009025 "mesothelial cell of colon")
EquivalentClasses(obo:CL_0009025 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003335)))

# Class: obo:CL_0009026 (enterocyte of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009026 "An enterocyte that is a part of a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009026 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009026 "appendix enterocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009026 "enterocyte of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009026 "enterocyte of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009026 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009026 "enterocyte of appendix")
EquivalentClasses(obo:CL_0009026 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))
SubClassOf(obo:CL_0009026 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697))

# Class: obo:CL_0009027 (transit amplifying cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009027 "A transit amplifying cell that is part of a crypt of Lieberkuhn of large intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009027 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009027 "appendix transit amplifying cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009027 "transit amplifying cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009027 "transit amplifying cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009027 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009027 "transit amplifying cell of appendix")
EquivalentClasses(obo:CL_0009027 ObjectIntersectionOf(obo:CL_4047017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013486)))
SubClassOf(obo:CL_0009027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0009028))

# Class: obo:CL_0009028 (intestinal crypt stem cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009028 "An intestinal crypt stem cell that is located in the vermiform appendix. These stem cells reside at the bottom of crypts in the appendix and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.")
AnnotationAssertion(terms:contributor obo:CL_0009028 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009028 "appendix intestinal crypt stem cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009028 "intestinal crypt stem cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009028 "intestinal crypt stem cell of vermiform appendix")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009028 "stem cell of intestinal crypt of Lieberkuhn of appendix")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009028 "stem cell of intestinal crypt of Lieberkuhn of appendix vermiformis")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009028 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009028 "intestinal crypt stem cell of appendix")
EquivalentClasses(obo:CL_0009028 ObjectIntersectionOf(obo:CL_0002250 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013486)))

# Class: obo:CL_0009029 (mesothelial cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009029 "A mesothelial cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009029 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009029 "appendix mesothelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009029 "mesothelial cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009029 "mesothelial cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009029 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009029 "mesothelial cell of appendix")
EquivalentClasses(obo:CL_0009029 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012498)))

# Class: obo:CL_0009030 (enteroendocrine cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009030 "An intestinal enteroendocrine cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009030 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009030 "appendix enteroendocrine cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009030 "enteroendocrine cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009030 "enteroendocrine cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009030 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009030 "enteroendocrine cell of appendix")
EquivalentClasses(obo:CL_0009030 ObjectIntersectionOf(obo:CL_1001516 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))
SubClassOf(obo:CL_0009030 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697))

# Class: obo:CL_0009031 (T cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009031 "A T cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009031 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009031 "T cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009031 "T cell of vermiform appendix")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009031 "appendix T cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009031 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009031 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009031 "T cell of appendix")
EquivalentClasses(obo:CL_0009031 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009032 (B cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009032 "A B cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009032 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009032 "B cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009032 "B cell of vermiform appendix")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009032 "appendix B cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009032 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009032 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009032 "B cell of appendix")
EquivalentClasses(obo:CL_0009032 ObjectIntersectionOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009033 (plasma cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009033 "A plasma cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009033 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009033 "appendix plasma cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009033 "plasma cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009033 "plasma cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009033 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009033 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009033 "plasma cell of appendix")
EquivalentClasses(obo:CL_0009033 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009034 (dendritic cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009034 "A dendritic cell that is located in a vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009034 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009034 "appendix dendritic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009034 "dendritic cell of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009034 "dendritic cell of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009034 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009034 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009034 "dendritic cell of appendix")
EquivalentClasses(obo:CL_0009034 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009035 (stromal cell of lamina propria of vermiform appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009035 "A stromal cell found in the lamina propria of the vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009035 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009035 "stromal cell of appendix lamina propria")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009035 "stromal cell of lamina propria of appendix vermiformis")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009035 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009035 "stromal cell of lamina propria of vermiform appendix")
EquivalentClasses(obo:CL_0009035 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011189)))

# Class: obo:CL_0009036 (appendix macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009036 "A macrophage located in the vermiform appendix.")
AnnotationAssertion(terms:contributor obo:CL_0009036 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009036 "macrophage of appendix")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009036 "macrophage of appendix vermiformis")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009036 "macrophage of vermiform appendix")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009036 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009036 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009036 "appendix macrophage")
EquivalentClasses(obo:CL_0009036 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))

# Class: obo:CL_0009037 (lymph node mantle zone B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8011279") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865/") Annotation(oboInOwl:hasDbXref "https://www.arppress.org/v/vspfiles/assets/images/Chapter1T25LymphNodes.pdf") obo:IAO_0000115 obo:CL_0009037 "A B lymphocyte that resides in the mantle zone of the lymph node germinal center. These are generally IgM and IgD positive activated B cells that form a 'corona' around the germinal center and are part of the establishment of a secondary lymphatic follicule.")
AnnotationAssertion(terms:contributor obo:CL_0009037 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009037 "mantle zone B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009037 "mantle zone B cell of lymph node")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009037 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009037 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009037 "lymph node mantle zone B cell")
EquivalentClasses(obo:CL_0009037 ObjectIntersectionOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010420)))

# Class: obo:CL_0009038 (colon macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009038 "A macrophage that is located in the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009038 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009038 "macrophage of colon")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009038 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009038 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009038 "colon macrophage")
EquivalentClasses(obo:CL_0009038 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))

# Class: obo:CL_0009039 (colon goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009039 "A goblet cell that is located in the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009039 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009039 "goblet cell of colon")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009039 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009039 "colon goblet cell")
EquivalentClasses(obo:CL_0009039 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))

# Class: obo:CL_0009040 (stromal cell of lamina propria of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009040 "A stromal cell found in the lamina propria of the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009040 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009040 "stromal cell of colon lamina propria")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009040 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009040 "stromal cell of lamina propria of colon")
EquivalentClasses(obo:CL_0009040 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007177)))

# Class: obo:CL_0009041 (tuft cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33079783") Annotation(oboInOwl:hasDbXref "PMID:35271673") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009041 "A tuft cell that is part of the colonic epithelium, primarily adapted for microbial sensing in the dense colonic microbiota. Unlike its small intestinal counterpart, it does not participate in parasite-driven tuft cell–ILC2 circuits. Instead, it detects bacterial metabolites via taste-signaling pathways (Strine and Craig, 2022). The colonic tuft cell plays a key role in epithelial repair, modulates inflammatory responses through IL-25 secretion, and contributes to intestinal homeostasis by balancing microbiome interactions (Sebastian et al., 2021).")
AnnotationAssertion(terms:contributor obo:CL_0009041 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009041 "colon tuft cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009041 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009041 "tuft cell of colon")
EquivalentClasses(obo:CL_0009041 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))

# Class: obo:CL_0009042 (enteroendocrine cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009042 "An enteroendocrine cell that is located in the colon.")
AnnotationAssertion(terms:contributor obo:CL_0009042 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009042 "colon enteroendocrine cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009042 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009042 "enteroendocrine cell of colon")
EquivalentClasses(obo:CL_0009042 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(obo:CL_0009042 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397))

# Class: obo:CL_0009043 (intestinal crypt stem cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10841502") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009043 "An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon.")
AnnotationAssertion(terms:contributor obo:CL_0009043 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009043 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009043 "intestinal crypt stem cell of colon")
EquivalentClasses(obo:CL_0009043 ObjectIntersectionOf(obo:CL_0002250 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013485)))

# Class: obo:CL_0009044 (lymphocyte of small intestine lamina propria)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26551552") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009044 "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response.")
AnnotationAssertion(terms:contributor obo:CL_0009044 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009044 "gastrointestinal tract small intestine (lamina propria) leukocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009044 "small intestine lamina propria leukocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009044 "small intestine lamina propria leukocyte (LPL)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009044 "gastrointestinal tract (lamina propria) lymphocyte of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009044 "lamina propria lymphocyte of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009044 "small intestine lamina propria lymphocyte")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009044 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009044 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009044 "lymphocyte of small intestine lamina propria")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0009044 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0009044 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001238)))

# Class: obo:CL_0009045 (B cell of medullary sinus of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009045 "A B cell found in the lymph node medullary sinus.")
AnnotationAssertion(terms:contributor obo:CL_0009045 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009045 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009045 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009045 "B cell of medullary sinus of lymph node")
EquivalentClasses(obo:CL_0009045 ObjectIntersectionOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009744)))

# Class: obo:CL_0009046 (T cell of medullary sinus of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009046 "A T cell found in the lymph node medullary sinus.")
AnnotationAssertion(terms:contributor obo:CL_0009046 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009046 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009046 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009046 "T cell of medullary sinus of lymph node")
EquivalentClasses(obo:CL_0009046 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009744)))

# Class: obo:CL_0009047 (macrophage of medullary sinus of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009047 "A macrophage found in the medullary sinus of the lymph node.")
AnnotationAssertion(terms:contributor obo:CL_0009047 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009047 "medullary sinus macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009047 "lymph node medullary sinus macrophage")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009047 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009047 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009047 "macrophage of medullary sinus of lymph node")
EquivalentClasses(obo:CL_0009047 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009744)))

# Class: obo:CL_0009048 (anorectum macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009048 "A macrophage that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009048 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009048 "macrophage of anorectum")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009048 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009048 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009048 "anorectum macrophage")
EquivalentClasses(obo:CL_0009048 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009049 (smooth muscle cell of high endothelial venule of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27881983") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009049 "A layer of smooth muscle cells that forms the outer layer of the high endothelial venule of lymph node and pumps to allow flow of lymph fluid carrying lymphocytes.")
AnnotationAssertion(terms:contributor obo:CL_0009049 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009049 "high endothelial venule smooth muscle cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009049 "high endothelial venule of lymph node smooth muscle cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009049 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009049 "smooth muscle cell of high endothelial venule of lymph node")
EquivalentClasses(obo:CL_0009049 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410038)))

# Class: obo:CL_0009050 (B cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009050 "A B cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009050 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009050 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009050 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009050 "B cell of anorectum")
EquivalentClasses(obo:CL_0009050 ObjectIntersectionOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009051 (T cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009051 "A T cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009051 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009051 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009051 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009051 "T cell of anorectum")
EquivalentClasses(obo:CL_0009051 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009052 (smooth muscle cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009052 "A smooth muscle cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009052 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009052 "anorectum smooth muscle cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009052 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009052 "smooth muscle cell of anorectum")
EquivalentClasses(obo:CL_0009052 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009053 (stromal cell of anorectum lamina propria)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009053 "A stromal cell found in the lamina propria of the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009053 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009053 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009053 "stromal cell of anorectum lamina propria")
EquivalentClasses(obo:CL_0009053 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011189) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009054 (microfold cell of epithelium proper of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009054 "A microfold cell (M cell) that is part of the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009054 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009054 "M cell of anorectum")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009054 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009054 "microfold cell of epithelium proper of anorectum")
EquivalentClasses(obo:CL_0009054 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))
SubClassOf(obo:CL_0009054 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_0009055 (paneth cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009055 "A paneth cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009055 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009055 "anorectum paneth cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009055 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009055 "paneth cell of anorectum")
EquivalentClasses(obo:CL_0009055 ObjectIntersectionOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))
SubClassOf(obo:CL_0009055 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_0009056 (transit amplifying cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009056 "A transit amplifying cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009056 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009056 "anorectum transit amplifying cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009056 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009056 "transit amplifying cell of anorectum")
EquivalentClasses(obo:CL_0009056 ObjectIntersectionOf(obo:CL_4047017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009057 (anorectum goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009057 "A goblet cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009057 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009057 "goblet cell of anorectum")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009057 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009057 "anorectum goblet cell")
EquivalentClasses(obo:CL_0009057 ObjectIntersectionOf(obo:CL_1000320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009058 (enterocyte of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009058 "An enterocyte that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009058 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009058 "anorectum enterocyte")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009058 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009058 "enterocyte of anorectum")
EquivalentClasses(obo:CL_0009058 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009059 (plasma cell of medullary sinus of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009059 "A plasma cell that is located in the medullary sinus of the lymph node.")
AnnotationAssertion(terms:contributor obo:CL_0009059 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009059 "medullary plasma cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009059 "medullary sinus plasma cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009059 "plasma cell of medullary sinus")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009059 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009059 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009059 "plasma cell of medullary sinus of lymph node")
EquivalentClasses(obo:CL_0009059 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009744)))

# Class: obo:CL_0009060 (marginal zone B cell of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Marginal_zone_B-cell&oldid=1032071222") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009060 "A mature B cell located in the marginal zone of the lymph node.")
AnnotationAssertion(terms:contributor obo:CL_0009060 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009060 "marginal zone B cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009060 "lymph node marginal zone B cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009060 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009060 "marginal zone B cell of lymph node")
EquivalentClasses(obo:CL_0009060 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410065)))

# Class: obo:CL_0009061 (intestinal crypt stem cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009061 "An intestinal crypt stem cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009061 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009061 "anorectum intestinal crypt stem cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009061 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009061 "intestinal crypt stem cell of anorectum")
EquivalentClasses(obo:CL_0009061 ObjectIntersectionOf(obo:CL_0009016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009062 (germinal center T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21739669") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009062 "A specialized type of CD4 positive T cell, the follicular helper T cell (TFH cell), that upregulates CXCR5 expression to enable its follicular localization. These specialised T cells reside in the germinal center of the lymph node.")
AnnotationAssertion(terms:contributor obo:CL_0009062 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009062 "T follicular helper cell of germinal center of lymph node")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009062 "T follicular helper cell of lymph node germinal center")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009062 "lymph node germinal center T follicular helper cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009062 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009062 "germinal center T cell")
EquivalentClasses(obo:CL_0009062 ObjectIntersectionOf(obo:CL_0002038 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009039)))

# Class: obo:CL_0009063 (enteroendocrine cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009063 "An enteroendocrine cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009063 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009063 "anorectum enteroendocrine cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009063 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009063 "enteroendocrine cell of anorectum")
EquivalentClasses(obo:CL_0009063 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))
SubClassOf(obo:CL_0009063 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_0009064 (lymph node paracortex T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009064 "A T cell located in the lymph node paracortex, where macrophages and dendritic cells present antigenic peptides to these naïve T cells, stimulating them to become activated helper T cells or cytotoxic T lymphocytes.")
AnnotationAssertion(terms:contributor obo:CL_0009064 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009064 "paracortex T cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009064 "paracortical T cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009064 "T cell of lymph node paracortex")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009064 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009064 "lymph node paracortex T cell")
EquivalentClasses(obo:CL_0009064 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410066)))

# Class: obo:CL_0009065 (tuft cell of anorectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009065 "An intestinal tuft cell that is located in the anorectum.")
AnnotationAssertion(terms:contributor obo:CL_0009065 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009065 "anorectum tuft cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009065 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009065 "tuft cell of anorectum")
EquivalentClasses(obo:CL_0009065 ObjectIntersectionOf(obo:CL_0019032 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410050)))

# Class: obo:CL_0009066 (stratified squamous epithelial cell of anal canal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") obo:IAO_0000115 obo:CL_0009066 "A stratified squamous epithelial cell that is part of the anal canal.")
AnnotationAssertion(terms:contributor obo:CL_0009066 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009066 "anal canal stratified squamous epithelial cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009066 pato:location_grouping)
AnnotationAssertion(rdfs:comment obo:CL_0009066 "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.")
AnnotationAssertion(rdfs:label obo:CL_0009066 "stratified squamous epithelial cell of anal canal")
EquivalentClasses(obo:CL_0009066 ObjectIntersectionOf(obo:CL_0000240 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015716)))

# Class: obo:CL_0009067 (vacuolated fetal-type enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17901585") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0002-7073-9172") obo:IAO_0000115 obo:CL_0009067 "An enterocyte found in the small intestine of newborn mammals and characterized by the presence of an apical canalicular system (ACS) leading to production of large vacuoles, important for colostral macromolecule uptake. After birth, the vacuolated fetal-type enterocytes are replaced with enterocytes lacking an ACS.")
AnnotationAssertion(terms:contributor obo:CL_0009067 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009067 "vacuolated enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasRelatedSynonym obo:CL_0009067 "early enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasRelatedSynonym obo:CL_0009067 "immature enterocyte")
AnnotationAssertion(rdfs:label obo:CL_0009067 "vacuolated fetal-type enterocyte")
SubClassOf(obo:CL_0009067 obo:CL_0000584)
SubClassOf(obo:CL_0009067 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108))
SubClassOf(obo:CL_0009067 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_40674))

# Class: obo:CL_0009068 (CD8aa(I) thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") obo:IAO_0000115 obo:CL_0009068 "An unconventional T lymphocyte population within the thymic medulla that is potentially a thymic resident population.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009068 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009068 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009068 "CD8aa(I) thymocyte")
SubClassOf(obo:CL_0009068 obo:CL_0000893)
SubClassOf(obo:CL_0009068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124))

# Class: obo:CL_0009069 (CD8aa(II) thymocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") obo:IAO_0000115 obo:CL_0009069 "An unconventional T lymphocyte population within the thymic medulla that expresses both alpha/beta and gamma/delta T cell signatures.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009069 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009069 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009069 "CD8aa(II) thymocyte")
SubClassOf(obo:CL_0009069 obo:CL_0000893)
SubClassOf(obo:CL_0009069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124))

# Class: obo:CL_0009070 (corticomedullary thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") obo:IAO_0000115 obo:CL_0009070 "A thymic epithelial cell located at the corticomedullary junction.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009070 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009070 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009070 "corticomedullary thymic epithelial cell")
SubClassOf(obo:CL_0009070 obo:CL_0002293)
SubClassOf(obo:CL_0009070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003988))

# Class: obo:CL_0009071 (medullary thymic epithelial cell type 1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24084687") Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") obo:IAO_0000115 obo:CL_0009071 "A thymic medullary epithelial cell considered to be a pre-AIRE mTEC population.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009071 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009071 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009071 "medullary thymic epithelial cell type 1")
SubClassOf(obo:CL_0009071 obo:CL_0002365)
SubClassOf(obo:CL_0009071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009072 (medullary thymic epithelial cell type 2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17067941") Annotation(oboInOwl:hasDbXref "PMID:24084687") Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") obo:IAO_0000115 obo:CL_0009072 "A thymic medullary epithelial cell that expresses AIRE or other canonical markers of mature mTECs like Fezf2.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009072 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009072 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009072 "medullary thymic epithelial cell type 2")
SubClassOf(obo:CL_0009072 obo:CL_0002365)
SubClassOf(obo:CL_0009072 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009073 (medullary thymic epithelial cell type 3)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16121185") Annotation(oboInOwl:hasDbXref "PMID:17067941") Annotation(oboInOwl:hasDbXref "PMID:20861360") Annotation(oboInOwl:hasDbXref "PMID:24084687") Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") Annotation(oboInOwl:hasDbXref "PMID:33868260") obo:IAO_0000115 obo:CL_0009073 "A thymic medullary epithelial cell considered to be a post-AIRE cell. This group of AIRE-mTECs is heterogeneous and also includes mTECs within Hassall's Corpuscles.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009073 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009073 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33868260") oboInOwl:hasExactSynonym obo:CL_0009073 "corneocyte-like mTECs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33868260") oboInOwl:hasExactSynonym obo:CL_0009073 "corneocyte-like medullary thymic epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33868260") oboInOwl:hasExactSynonym obo:CL_0009073 "post-Aire cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33868260") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0009073 "mTEC III")
AnnotationAssertion(rdfs:label obo:CL_0009073 "medullary thymic epithelial cell type 3")
SubClassOf(obo:CL_0009073 obo:CL_0002365)
SubClassOf(obo:CL_0009073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009074 (medullary thymic epithelial cell type 4)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30022164") Annotation(oboInOwl:hasDbXref "PMID:32079746") obo:IAO_0000115 obo:CL_0009074 "A thymic medullary epithelial cell that expresses typical tuft cell markers instead of classical mTEC or cTEC markers. This population has a bulbous-like structure.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009074 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009074 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009074 "thymic tuft cell")
AnnotationAssertion(rdfs:label obo:CL_0009074 "medullary thymic epithelial cell type 4")
SubClassOf(obo:CL_0009074 obo:CL_0002365)
SubClassOf(obo:CL_0009074 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009075 (myo-medullary thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") obo:IAO_0000115 obo:CL_0009075 "A thymic medullary epithelial cell that expresses muscle-specific biomarkers.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009075 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009075 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009075 "myo-medullary thymic epithelial cell")
SubClassOf(obo:CL_0009075 obo:CL_0002365)
SubClassOf(obo:CL_0009075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009076 (neuro-medullary thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") Annotation(oboInOwl:hasDbXref "PMID:33597545") obo:IAO_0000115 obo:CL_0009076 "A thymic medullary epithelial cell that expresses neuroendocrine biomarkers.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009076 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009076 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009076 "neuro-medullary thymic epithelial cell")
SubClassOf(obo:CL_0009076 obo:CL_0002365)
SubClassOf(obo:CL_0009076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846))

# Class: obo:CL_0009077 (subcapsular thymic epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6209968") obo:IAO_0000115 obo:CL_0009077 "A thymic epithelial cell located within the subcapsular region of the thymus.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009077 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009077 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009077 "subcapsular thymic epithelial cell")
SubClassOf(obo:CL_0009077 obo:CL_0002364)
SubClassOf(obo:CL_0009077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006936))

# Class: obo:CL_0009078 (thymic fibroblast type 1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") obo:IAO_0000115 obo:CL_0009078 "A fibroblast located in the thymic capsule.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009078 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009078 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009078 "thymic capsular fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0009078 "thymic fibroblast type 1")
SubClassOf(obo:CL_0009078 obo:CL_0000057)
SubClassOf(obo:CL_0009078 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002122))

# Class: obo:CL_0009079 (thymic fibroblast type 2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32079746") obo:IAO_0000115 obo:CL_0009079 "A fibroblast located between thymic lobules.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009079 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009079 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009079 "thymic interlobular fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0009079 "thymic fibroblast type 2")
SubClassOf(obo:CL_0009079 obo:CL_0000057)
SubClassOf(obo:CL_0009079 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004791))

# Class: obo:CL_0009080 (tuft cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009080 "A tuft cell located in the small intestine.")
AnnotationAssertion(terms:contributor obo:CL_0009080 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009080 "brush cell of epithelium of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009080 "brush cell of epithelium proper of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009080 "brush cell of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009080 "tuft cell of epithelium of small intestine")
AnnotationAssertion(rdfs:label obo:CL_0009080 "tuft cell of small intestine")
AnnotationAssertion(Annotation(terms:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_0009080 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_0009080 ObjectIntersectionOf(obo:CL_0019032 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(obo:CL_0009080 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_0009081 (specified double negative thymocyte (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32304633") obo:IAO_0000115 obo:CL_0009081 "The human equivalent of a DN2 thymocyte; typically contains two phases, in the latter of which these thymocytes begin the process of beta selection.")
AnnotationAssertion(terms:contributor obo:CL_0009081 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009081 "2021-11-25T09:26:32Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0009081 "There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in human versus mouse thymus. This term is restricted for use with human data.")
AnnotationAssertion(rdfs:label obo:CL_0009081 "specified double negative thymocyte (Homo sapiens)")
SubClassOf(obo:CL_0009081 obo:CL_0002489)
SubClassOf(obo:CL_0009081 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_0009082 (committed double negative thymocyte (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32304633") obo:IAO_0000115 obo:CL_0009082 "The human equivalent of a DN3 thymocyte; these thymocytes finish the process of beta selection.")
AnnotationAssertion(terms:contributor obo:CL_0009082 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009082 "2021-11-25T09:30:45Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0009082 "There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in human versus mouse thymus. This term is restricted for use with human data.")
AnnotationAssertion(rdfs:label obo:CL_0009082 "committed double negative thymocyte (Homo sapiens)")
SubClassOf(obo:CL_0009082 obo:CL_0002489)
SubClassOf(obo:CL_0009082 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_0009083 (rearranging double negative thymocyte (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32304633") obo:IAO_0000115 obo:CL_0009083 "The human equivalent of a DN4 thymocyte.")
AnnotationAssertion(terms:contributor obo:CL_0009083 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009083 "2021-11-25T09:32:13Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0009083 "There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in human versus mouse thymus. This term is restricted for use with human data.")
AnnotationAssertion(rdfs:label obo:CL_0009083 "rearranging double negative thymocyte (Homo sapiens)")
SubClassOf(obo:CL_0009083 obo:CL_0002489)
SubClassOf(obo:CL_0009083 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_0009084 (glandular epithelial cell of endometrium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009084 "An epithelial cell that is part of an endometrium glandular epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0009084 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009084 "2021-11-30T16:13:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009084 "EFO:0010710")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009084 "endometrial glandular epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009084 "epithelial cell of endometrial gland")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009084 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009084 "glandular epithelial cell of endometrium")
EquivalentClasses(obo:CL_0009084 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012276)))

# Class: obo:CL_0009085 (colony forming unit – Hill cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Endothelial_progenitor_cell&oldid=1069930016#Colony_forming_unit_–_Hill") obo:IAO_0000115 obo:CL_0009085 "An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. They may form discrete colonies.")
AnnotationAssertion(terms:contributor obo:CL_0009085 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009085 "2022-02-18T09:55:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009085 "CFU-Hill")
AnnotationAssertion(rdfs:label obo:CL_0009085 "colony forming unit – Hill cell")
SubClassOf(obo:CL_0009085 obo:CL_0002619)

# Class: obo:CL_0009086 (endothelial cell of respiratory system lymphatic vessel)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009086 "An endothelial cell that is part of a respiratory system lymphatic vessel.")
AnnotationAssertion(terms:contributor obo:CL_0009086 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009086 "2021-12-03T14:00:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009086 "EFO:0010667")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009086 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009086 "endothelial cell of respiratory system lymphatic vessel")
EquivalentClasses(obo:CL_0009086 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003456)))
SubClassOf(obo:CL_0009086 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003529))

# Class: obo:CL_0009087 (fused extravillous trophoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009087 "An extravillous trophoblast that is polynuclear.")
AnnotationAssertion(terms:contributor obo:CL_0009087 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009087 "2021-12-03T14:37:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009087 "EFO:0010712")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009087 "fused EVT")
AnnotationAssertion(rdfs:label obo:CL_0009087 "fused extravillous trophoblast")
SubClassOf(obo:CL_0009087 obo:CL_0008036)

# Class: obo:CL_0009088 (circulating angiogenic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Endothelial_progenitor_cell&oldid=1069930016#Circulating_angiogenic_cell") obo:IAO_0000115 obo:CL_0009088 "An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. These cells do not form colonies.")
AnnotationAssertion(terms:contributor obo:CL_0009088 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009088 "2022-02-18T10:12:57Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0009088 "circulating angiogenic cell")
SubClassOf(obo:CL_0009088 obo:CL_0002619)

# Class: obo:CL_0009089 (lung pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009089 "A pericyte cell that is part of a lung.")
AnnotationAssertion(terms:contributor obo:CL_0009089 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009089 "2021-12-03T17:13:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009089 "EFO:0010669")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009089 "lung pericyte cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009089 "pulmonary pericyte")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009089 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009089 "lung pericyte")
EquivalentClasses(obo:CL_0009089 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))

# Class: obo:CL_0009090 (endothelial colony forming cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33419165") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Endothelial_colony_forming_cell&oldid=1068242094") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0002-0819-0473") obo:IAO_0000115 obo:CL_0009090 "An adult endothelial progenitor cell that is resident of adult vasculature and capable of differentiating to regenerate endothelial cell populations. Endothelial colony forming cells are characterised in vivo by clonal proliferative status, de novo vessel formation, homing to ischemic sites and paracrine support of angiogenesis. These cells are phenotypically similar to endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_0009090 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009090 "2022-02-18T10:15:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009090 "ECFC")
AnnotationAssertion(rdfs:label obo:CL_0009090 "endothelial colony forming cell")
SubClassOf(obo:CL_0009090 obo:CL_0002619)
SubClassOf(obo:CL_0009090 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004537))

# Class: obo:CL_0009091 (Leydig stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21181888") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0002-0819-0473") obo:IAO_0000115 obo:CL_0009091 "A stem cell found in the interstitial compartment of the neonatal testis; it is capable of self-renewal as well as differentiation into steroidogenic cells (adult Leydig cells). Intermediate stages of development include progenitor Leydig cells and immature Leydig cells.")
AnnotationAssertion(terms:contributor obo:CL_0009091 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009091 "2022-02-18T14:09:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009091 "stem Leydig cell")
AnnotationAssertion(rdfs:label obo:CL_0009091 "Leydig stem cell")
SubClassOf(obo:CL_0009091 obo:CL_0000034)
SubClassOf(obo:CL_0009091 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005212))

# Class: obo:CL_0009092 (endothelial cell of placenta)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009092 "An endothelial cell that is part of a placenta.")
AnnotationAssertion(terms:contributor obo:CL_0009092 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009092 "2021-12-13T13:53:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009092 "EFO:0010708")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009092 "placental endothelial cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009092 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009092 "endothelial cell of placenta")
EquivalentClasses(obo:CL_0009092 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_0009093 (smooth muscle cell of placenta)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009093 "A smooth muscle cell that is part of a placenta.")
AnnotationAssertion(terms:contributor obo:CL_0009093 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009093 "2021-12-13T13:56:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009093 "EFO:0010709")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009093 "placental smooth muscle cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009093 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009093 "smooth muscle cell of placenta")
EquivalentClasses(obo:CL_0009093 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_0009094 (endothelial cell of hepatic portal vein)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30348985") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009094 "An endothelial cell that is part of a hepatic portal vein.")
AnnotationAssertion(terms:contributor obo:CL_0009094 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009094 "2021-12-13T14:01:05Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009094 "portal endothelial cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009094 "EFO:0010704")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009094 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009094 "endothelial cell of hepatic portal vein")
EquivalentClasses(obo:CL_0009094 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001639)))

# Class: obo:CL_0009095 (endothelial cell of uterus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-3440-1876") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4183-8865") obo:IAO_0000115 obo:CL_0009095 "An endothelial cell that is part of a uterus.")
AnnotationAssertion(terms:contributor obo:CL_0009095 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009095 "2021-12-13T14:39:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0009095 "EFO:0010711")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009095 "uterine endothelial cell")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0009095 pato:location_grouping)
AnnotationAssertion(rdfs:label obo:CL_0009095 "endothelial cell of uterus")
EquivalentClasses(obo:CL_0009095 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000995)))

# Class: obo:CL_0009096 (esophagus non-keratinized squamous epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11694559") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-2034-601X") obo:IAO_0000115 obo:CL_0009096 "Any cell that is part of the esophageal non-keratinized stratified squamous epithelium. In humans, the esophagus, which requires flexibility to accommodate swallowing of a bolus, is covered with a non-keratinized epithelium.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009096 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009096 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009096 "2022-02-21T15:00:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "esophageal non-keratinized squamous epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "esophageal nonkeratinized squamous epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "esophagus non-keratinizing squamous epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "esophagus nonkeratinizing squamous epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "non-keratinized squamous epithelial cell of esophagus")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "non-keratinizing squamous epithelial cell of esophagus")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "nonkeratinized squamous epithelial cell of esophagus")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009096 "nonkeratinizing squamous epithelial cell of esophagus")
AnnotationAssertion(rdfs:label obo:CL_0009096 "esophagus non-keratinized squamous epithelial cell")
EquivalentClasses(obo:CL_0009096 ObjectIntersectionOf(obo:CL_0000238 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006920)))

# Class: obo:CL_0009097 (embryonic skeletal muscle fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32094117") Annotation(oboInOwl:hasDbXref "PMID:7196501") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-2034-601X") obo:IAO_0000115 obo:CL_0009097 "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development.")
AnnotationAssertion(terms:contributor obo:CL_0009097 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009097 "2022-02-21T15:39:10Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0009097 "embryonic skeletal muscle fiber")
EquivalentClasses(obo:CL_0009097 ObjectIntersectionOf(obo:CL_0008002 ObjectSomeValuesFrom(obo:RO_0002491 obo:UBERON_0000068)))

# Class: obo:CL_0009098 (fetal and neonatal skeletal muscle fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26180627") Annotation(oboInOwl:hasDbXref "PMID:7196501") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0003-2034-601X") obo:IAO_0000115 obo:CL_0009098 "A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins.")
AnnotationAssertion(terms:contributor obo:CL_0009098 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009098 "2022-02-21T15:43:16Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0009098 "fetal and neonatal skeletal muscle fiber")
EquivalentClasses(obo:CL_0009098 ObjectIntersectionOf(obo:CL_0008002 ObjectSomeValuesFrom(obo:RO_0002488 obo:UBERON_0000092) ObjectSomeValuesFrom(obo:RO_0002492 obo:UBERON_0007221)))

# Class: obo:CL_0009099 (fibro/adipogenic progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20081841") Annotation(oboInOwl:hasDbXref "PMID:22045730") Annotation(oboInOwl:hasDbXref "PMID:24605102") obo:IAO_0000115 obo:CL_0009099 "A progenitor cell that is a tissue-resident mesenchymal cell, important for skeletal muscle regeneration, and able to differentiate into both adipocytes or fibroblasts.")
AnnotationAssertion(terms:contributor obo:CL_0009099 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009099 "2022-02-21T16:50:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009099 "fibro/adipogenic progenitor")
AnnotationAssertion(rdfs:label obo:CL_0009099 "fibro/adipogenic progenitor cell")
SubClassOf(obo:CL_0009099 obo:CL_0008019)
SubClassOf(obo:CL_0009099 obo:CL_0011026)

# Class: obo:CL_0009100 (hepatic portal fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20209607") Annotation(oboInOwl:hasDbXref "PMID:24814904") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009100 "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.")
AnnotationAssertion(terms:contributor obo:CL_0009100 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009100 "2022-03-17T12:00:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009100 "portal fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0009100 "hepatic portal fibroblast")
EquivalentClasses(obo:CL_0009100 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001279)))

# Class: obo:CL_0009101 (fibroblastic reticular cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0009101 "A reticular cell involved in directing B cells and T cells to specific regions within a tissue.")
AnnotationAssertion(terms:contributor obo:CL_0009101 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009101 "2022-03-21T15:20:33Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35440118") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0009101 "FRC")
AnnotationAssertion(rdfs:label obo:CL_0009101 "fibroblastic reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009101 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0009101 obo:CL_0000186)
SubClassOf(obo:CL_0009101 obo:CL_0000432)

# Class: obo:CL_0009102 (lymph node fibroblastic reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21435450") Annotation(oboInOwl:hasDbXref "PMID:22566825") Annotation(oboInOwl:hasDbXref "PMID:25998961") Annotation(oboInOwl:hasDbXref "PMID:28262465") Annotation(oboInOwl:hasDbXref "PMID:29752062") Annotation(oboInOwl:hasDbXref "PMID:34256989") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009102 "A specialized, fibroblastic reticular cell of mesenchymal origin found in lymph nodes. In human, it expresses several markers common to myofibroblasts (desmin, vimentin, CD73, CD90, α-smooth muscle actin (αSMA)), and can be differentiated from endothelial cells by its lack of CD31 expression. These cells are critical for the overall organization and function of the lymph node. Lymph node fibroblastic reticular cells (FRCs) can be further classified based on their location, function, and unique marker expression.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009102 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009102 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009102 "2022-03-21T15:24:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009102 "fibroblastic reticular cell")
AnnotationAssertion(rdfs:label obo:CL_0009102 "lymph node fibroblastic reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009102 "https://github.com/obophenotype/cell-ontology/issues/1472")
EquivalentClasses(obo:CL_0009102 ObjectIntersectionOf(obo:CL_0009101 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000029)))

# Class: obo:CL_0009103 (lymph node marginal reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21435450") Annotation(oboInOwl:hasDbXref "PMID:22566825") Annotation(oboInOwl:hasDbXref "PMID:25998961") Annotation(oboInOwl:hasDbXref "PMID:28262465") Annotation(oboInOwl:hasDbXref "PMID:29752062") Annotation(oboInOwl:hasDbXref "PMID:34256989") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009103 "A fibroblastic reticular cell found in the lymph node subcapsular sinus.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009103 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009103 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009103 "2022-03-21T15:59:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009103 "marginal reticular cell")
AnnotationAssertion(rdfs:label obo:CL_0009103 "lymph node marginal reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009103 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0009103 obo:CL_0009102)
SubClassOf(obo:CL_0009103 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0005463))

# Class: obo:CL_0009104 (B cell zone reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21435450") Annotation(oboInOwl:hasDbXref "PMID:22566825") Annotation(oboInOwl:hasDbXref "PMID:25998961") Annotation(oboInOwl:hasDbXref "PMID:28262465") Annotation(oboInOwl:hasDbXref "PMID:29752062") Annotation(oboInOwl:hasDbXref "PMID:34256989") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009104 "A fibroblastic reticular cell found in the lymph node germinal center dark zone (B cell zone).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009104 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009104 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009104 "2022-03-21T16:55:46Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009104 "lymph node germinal center dark zone fibroblastic reticular cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0009104 "T-B boundary reticular cell")
AnnotationAssertion(rdfs:comment obo:CL_0009104 "B cell zone reticular cells share similarities with Ch25h-expresssing Ccl19lo T reticular cells found at the B cell follicle T zone interface of mouse lymph nodes.")
AnnotationAssertion(rdfs:label obo:CL_0009104 "B cell zone reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009104 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0009104 obo:CL_0009102)
SubClassOf(obo:CL_0009104 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410053))

# Class: obo:CL_0009105 (T cell zone reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21435450") Annotation(oboInOwl:hasDbXref "PMID:22566825") Annotation(oboInOwl:hasDbXref "PMID:25998961") Annotation(oboInOwl:hasDbXref "PMID:28262465") Annotation(oboInOwl:hasDbXref "PMID:29752062") Annotation(oboInOwl:hasDbXref "PMID:34256989") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009105 "A fibroblastic reticular cell found in the lymph node T cell domain.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009105 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009105 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009105 "2022-03-21T17:19:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009105 "lymph node T cell domain fibroblastic reticular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34256989") oboInOwl:hasRelatedSynonym obo:CL_0009105 "interfollicular reticular cell")
AnnotationAssertion(rdfs:label obo:CL_0009105 "T cell zone reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009105 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0009105 obo:CL_0009102)
SubClassOf(obo:CL_0009105 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010417))

# Class: obo:CL_0009106 (medullary reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21435450") Annotation(oboInOwl:hasDbXref "PMID:22566825") Annotation(oboInOwl:hasDbXref "PMID:25998961") Annotation(oboInOwl:hasDbXref "PMID:28262465") Annotation(oboInOwl:hasDbXref "PMID:29752062") Annotation(oboInOwl:hasDbXref "PMID:33981032") Annotation(oboInOwl:hasDbXref "PMID:34256989") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009106 "A specialized fibroblast found in the medulla of lymph node.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009106 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009106 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009106 "2022-03-22T09:03:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009106 "lymph node medullary reticular cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009106 "medullary reticular cell of lymph node")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0009106 "MedRC")
AnnotationAssertion(rdfs:comment obo:CL_0009106 "Origin and phenotype of medullary reticular cells are less well understood in humans than in mice.")
AnnotationAssertion(rdfs:label obo:CL_0009106 "medullary reticular cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009106 "https://github.com/obophenotype/cell-ontology/issues/1472")
SubClassOf(obo:CL_0009106 obo:CL_0009102)
SubClassOf(obo:CL_0009106 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002007))

# Class: obo:CL_0009107 (lymphatic endothelial cell of subcapsular sinus ceiling)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31402260") Annotation(oboInOwl:hasDbXref "PMID:32426372") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009107 "A lymphatic endothelial cell located in the subcapsular sinus ceiling of a lymph node. In human, it's characterized by a unique marker expression (NT5e+ and Caveolin-1+).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009107 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009107 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009107 "2022-03-22T10:30:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009107 "lymphatic endothelial cell of subcapsular sinus ceiling of lymph node")
AnnotationAssertion(rdfs:label obo:CL_0009107 "lymphatic endothelial cell of subcapsular sinus ceiling")
SubClassOf(obo:CL_0009107 obo:CL_0002138)
SubClassOf(obo:CL_0009107 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410071))

# Class: obo:CL_0009108 (lymphatic endothelial cell of subcapsular sinus floor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31402260") Annotation(oboInOwl:hasDbXref "PMID:32426372") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009108 "A lymphatic endothelial cell located in the subcapsular sinus floor of a lymph node. In human, it's characterized by a unique marker expression (TNFRSF9+).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009108 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009108 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009108 "2022-03-22T10:39:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009108 "lymphatic endothelial cell of subcapsular sinus floor of lymph node")
AnnotationAssertion(rdfs:label obo:CL_0009108 "lymphatic endothelial cell of subcapsular sinus floor")
SubClassOf(obo:CL_0009108 obo:CL_0002138)
SubClassOf(obo:CL_0009108 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410072))

# Class: obo:CL_0009109 (lymphatic endothelial cell of trabecula)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31402260") Annotation(oboInOwl:hasDbXref "PMID:32426372") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009109 "A lymphatic endothelial cell located in a lymph node trabecula.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009109 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009109 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009109 "2022-03-23T15:08:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009109 "lymphatic endothelial cell of lymph node trabecula")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009109 "lymphatic endothelial cell of trabeculae")
AnnotationAssertion(rdfs:label obo:CL_0009109 "lymphatic endothelial cell of trabecula")
SubClassOf(obo:CL_0009109 obo:CL_0002138)
SubClassOf(obo:CL_0009109 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002195))

# Class: obo:CL_0009110 (lymphatic endothelial cell of medulla ceiling)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31402260") Annotation(oboInOwl:hasDbXref "PMID:32426372") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009110 "A lymphatic endothelial cell located in the ceiling part of a lymph node medulla.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009110 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009110 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009110 "2022-03-23T15:13:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009110 "lymphatic endothelial cell of lymph node medulla ceiling")
AnnotationAssertion(rdfs:label obo:CL_0009110 "lymphatic endothelial cell of medulla ceiling")
SubClassOf(obo:CL_0009110 obo:CL_0002138)
SubClassOf(obo:CL_0009110 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002007))

# Class: obo:CL_0009111 (centrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17067937") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009111 "A germinal center B cell found in a lymph node germinal center light zone.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009111 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009111 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009111 "2022-03-24T09:03:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009111 "lymph node centrocyte")
AnnotationAssertion(rdfs:label obo:CL_0009111 "centrocyte")
SubClassOf(obo:CL_0009111 obo:CL_0000844)
SubClassOf(obo:CL_0009111 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410052))

# Class: obo:CL_0009112 (centroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17067937") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009112 "A germinal center B cell found in a lymph node germinal center dark zone.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009112 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009112 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009112 "2022-03-24T09:12:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009112 "lymph node centroblast")
AnnotationAssertion(rdfs:label obo:CL_0009112 "centroblast")
SubClassOf(obo:CL_0009112 obo:CL_0000844)
SubClassOf(obo:CL_0009112 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410053))

# Class: obo:CL_0009113 (T follicular regulatory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15578096") Annotation(oboInOwl:hasDbXref "PMID:26501424") Annotation(oboInOwl:hasDbXref "PMID:29769249") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009113 "A regulatory T cell present in the B cell follicles and germinal centers of lymphoid tissues. In humans, it is CXCR5+.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009113 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009113 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009113 "2022-03-24T09:36:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009113 "follicular regulatory T cell")
AnnotationAssertion(rdfs:label obo:CL_0009113 "T follicular regulatory cell")
SubClassOf(obo:CL_0009113 obo:CL_0000815)
SubClassOf(obo:CL_0009113 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001744))

# Class: obo:CL_0009114 (monocytoid B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33324003") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009114 "A B cell found in the perisinusoidal area of a lymph node. In humans, monocytoid B cells are a morphologically distinct B cell population
(oval nuclei, abundant cytoplasm, monocyte-like appearance), share many similarities with marginal zone B cells including marker expression, and are increased in disease settings.")
AnnotationAssertion(obo:RO_0002175 obo:CL_0009114 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_0009114 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(terms:date obo:CL_0009114 "2022-03-24T10:18:12Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0009114 "monocytoid B cell")
SubClassOf(obo:CL_0009114 obo:CL_0000236)
SubClassOf(obo:CL_0009114 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410066))

# Class: obo:CL_0009115 (lymph node lymphatic vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7655-4833") obo:IAO_0000115 obo:CL_0009115 "An endothelial cell located in a lymph node lymphatic vessel.")
AnnotationAssertion(terms:contributor obo:CL_0009115 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(rdfs:label obo:CL_0009115 "lymph node lymphatic vessel endothelial cell")
AnnotationAssertion(rdfs:seeAlso obo:CL_0009115 "https://github.com/obophenotype/cell-ontology/issues/1472")
EquivalentClasses(obo:CL_0009115 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000029) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001473)))

# Class: obo:CL_0009116 (progenitor cell of mammary luminal epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19063729") Annotation(oboInOwl:hasDbXref "PMID:20346151") Annotation(oboInOwl:hasDbXref "PMID:21930782") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4412-7970") obo:IAO_0000115 obo:CL_0009116 "A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells.")
AnnotationAssertion(terms:contributor obo:CL_0009116 <https://orcid.org/0000-0002-2825-0621>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0009116 "luminal progenitor cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0009116 "progenitor cell of luminal mammary epithelium")
AnnotationAssertion(rdfs:label obo:CL_0009116 "progenitor cell of mammary luminal epithelium")
SubClassOf(obo:CL_0009116 obo:CL_0011026)
SubClassOf(obo:CL_0009116 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911))

# Class: obo:CL_0010000 (keratinized cell of hair follicle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://github.com/obophenotype/cell-ontology/issues/417>) Annotation(oboInOwl:hasDbXref "PMID:2478566") Annotation(oboInOwl:hasDbXref "PMID:28445731") Annotation(oboInOwl:hasDbXref "PMID:30420661") obo:IAO_0000115 obo:CL_0010000 "A differentiating matrix keratinocyte that has initiated terminal differentiation and keratin synthesis. This cell undergoes a characteristic change while migrating upward from the hair follicle bulb, representing a committed progenitor cell destined to form the hair medulla, cortex and hair root sheath.")
AnnotationAssertion(terms:date obo:CL_0010000 "2025-01-24T12:00:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0010000 "keratinized cell of hair follicle")
SubClassOf(obo:CL_0010000 obo:CL_2000092)
SubClassOf(obo:CL_0010000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005932))

# Class: obo:CL_0010001 (stromal cell of bone marrow)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0010001 "A stromal cell that is part_of a bone marrow.")
AnnotationAssertion(terms:contributor obo:CL_0010001 <https://orcid.org/0000-0002-6601-2165>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010001 "bone marrow stromal cell")
AnnotationAssertion(rdfs:label obo:CL_0010001 "stromal cell of bone marrow")
EquivalentClasses(obo:CL_0010001 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))

# Class: obo:CL_0010002 (epithelial cell of umbilical artery)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0010002 "An epithelial cell that is part_of a umbilical artery.")
AnnotationAssertion(terms:contributor obo:CL_0010002 <https://orcid.org/0000-0002-6601-2165>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010002 "umbilical artery epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0010002 "epithelial cell of umbilical artery")
EquivalentClasses(obo:CL_0010002 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001310)))

# Class: obo:CL_0010003 (obsolete epithelial cell of alveolus of lung)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0010003 "OBSOLETE. An epithelial cell that is part_of a alveolus of lung.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0010003 <https://github.com/obophenotype/cell-ontology/issues/2429>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0010003 obo:CL_0000322)
AnnotationAssertion(terms:contributor obo:CL_0010003 <https://orcid.org/0000-0002-6601-2165>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0010003 "MESH:D056809")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010003 "alveolus of lung epithelial cell")
AnnotationAssertion(rdfs:comment obo:CL_0010003 "This cell type is exactly the same as 'pulmonary alveolar epithelial cell'.")
AnnotationAssertion(rdfs:label obo:CL_0010003 "obsolete epithelial cell of alveolus of lung")
AnnotationAssertion(owl:deprecated obo:CL_0010003 "true"^^xsd:boolean)

# Class: obo:CL_0010004 (mononuclear cell of bone marrow)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0010004 "A mononuclear cell that is part_of a bone marrow.")
AnnotationAssertion(terms:contributor obo:CL_0010004 <https://orcid.org/0000-0002-6601-2165>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010004 "bone marrow mononuclear cell")
AnnotationAssertion(rdfs:label obo:CL_0010004 "mononuclear cell of bone marrow")
EquivalentClasses(obo:CL_0010004 ObjectIntersectionOf(obo:CL_0000842 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))

# Class: obo:CL_0010005 (atrioventricular bundle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mtg_heart") obo:IAO_0000115 obo:CL_0010005 "A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010005 "AV bundle cell")
AnnotationAssertion(rdfs:label obo:CL_0010005 "atrioventricular bundle cell")
EquivalentClasses(obo:CL_0010005 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002353)))

# Class: obo:CL_0010006 (cardiac blood vessel endothelial cell)

AnnotationAssertion(rdfs:label obo:CL_0010006 "cardiac blood vessel endothelial cell")
EquivalentClasses(obo:CL_0010006 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000948)))

# Class: obo:CL_0010007 (His-Purkinje system cell)

AnnotationAssertion(rdfs:label obo:CL_0010007 "His-Purkinje system cell")
EquivalentClasses(obo:CL_0010007 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004146)))

# Class: obo:CL_0010008 (cardiac endothelial cell)

AnnotationAssertion(rdfs:label obo:CL_0010008 "cardiac endothelial cell")
EquivalentClasses(obo:CL_0010008 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000948)))

# Class: obo:CL_0010009 (camera-type eye photoreceptor cell)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010009 "camera type eye photoreceptor cell")
AnnotationAssertion(rdfs:label obo:CL_0010009 "camera-type eye photoreceptor cell")
EquivalentClasses(obo:CL_0010009 ObjectIntersectionOf(obo:CL_0000210 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000019)))
SubClassOf(Annotation(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/2245") obo:CL_0010009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966))

# Class: obo:CL_0010010 (cerebellar stellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31110133") Annotation(oboInOwl:hasDbXref "PMID:5042759") obo:IAO_0000115 obo:CL_0010010 "A GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell receives excitatory inputs primarily from parallel fibers and plays a crucial role in feed-forward inhibition by suppressing the activity of Purkinje cells and modulating the output of the cerebellar cortex. The stellate cell is part of the local circuitry that contributes to the fine-tuning of motor coordination and a regulator of cerebellar blood flow via neurovascular coupling.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31110133") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0010010 "cerebellar SC")
AnnotationAssertion(rdfs:label obo:CL_0010010 "cerebellar stellate cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_0010010 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0010010 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
EquivalentClasses(obo:CL_0010010 ObjectIntersectionOf(obo:CL_0000122 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002974)))
SubClassOf(obo:CL_0010010 obo:CL_0000099)
SubClassOf(obo:CL_0010010 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0010011 (cerebral cortex GABAergic interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0010011 "A GABAergic interneuron whose soma is located in the cerebral cortex.")
AnnotationAssertion(rdfs:label obo:CL_0010011 "cerebral cortex GABAergic interneuron")
EquivalentClasses(obo:CL_0010011 ObjectIntersectionOf(obo:CL_0011005 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_0010012 (cerebral cortex neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0010012 "A CNS neuron of the cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_0010012 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0010012 "BTO:0004102")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0010012 "FMA:84104")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010012 "cortical neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010012 "neuron of cerebral cortex")
AnnotationAssertion(rdfs:label obo:CL_0010012 "cerebral cortex neuron")
AnnotationAssertion(rdfs:seeAlso obo:CL_0010012 "https://github.com/obophenotype/cell-ontology/issues/1359")
EquivalentClasses(obo:CL_0010012 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_0010013 (type I pinealocyte)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010013 "light pinealocyte")
AnnotationAssertion(rdfs:label obo:CL_0010013 "type I pinealocyte")
SubClassOf(obo:CL_0010013 obo:CL_0000652)

# Class: obo:CL_0010014 (type II pinealocyte)

AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0010014 "dark pinealocyte")
AnnotationAssertion(rdfs:label obo:CL_0010014 "type II pinealocyte")
SubClassOf(obo:CL_0010014 obo:CL_0000652)

# Class: obo:CL_0010015 (coronet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:mr") Annotation(oboInOwl:hasDbXref "PMID:17595538") obo:IAO_0000115 obo:CL_0010015 "A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess.")
AnnotationAssertion(rdfs:comment obo:CL_0010015 "Editor note: remember to link to Saccus vasculosus in next uberon release")
AnnotationAssertion(rdfs:label obo:CL_0010015 "coronet cell")
SubClassOf(obo:CL_0010015 obo:CL_0000066)

# Class: obo:CL_0010016 (collar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25840473") obo:IAO_0000115 obo:CL_0010016 "A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms.")
AnnotationAssertion(rdfs:label obo:CL_0010016 "collar cell")
SubClassOf(obo:CL_0010016 obo:CL_0000000)
SubClassOf(obo:CL_0010016 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005929))

# Class: obo:CL_0010017 (zygote)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0010017 "A zygote in a plant or an animal.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0010017 "MESH:D015053")
AnnotationAssertion(rdfs:label obo:CL_0010017 "zygote"@en)
AnnotationAssertion(rdfs:seeAlso obo:CL_0010017 <https://github.com/obophenotype/cell-ontology/issues/786>)
SubClassOf(obo:CL_0010017 obo:CL_0000000)

# Class: obo:CL_0010020 (cardiac glial cell)

AnnotationAssertion(rdfs:label obo:CL_0010020 "cardiac glial cell")
EquivalentClasses(obo:CL_0010020 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000948)))

# Class: obo:CL_0010021 (cardiac myoblast)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0010021 "MESH:D032386")
AnnotationAssertion(rdfs:label obo:CL_0010021 "cardiac myoblast")
EquivalentClasses(obo:CL_0010021 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000746)))

# Class: obo:CL_0010022 (cardiac neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12486170") Annotation(oboInOwl:hasDbXref "PMID:29265764") obo:IAO_0000115 obo:CL_0010022 "A neuron that has its soma in the heart.")
AnnotationAssertion(rdfs:comment obo:CL_0010022 "This term is used in 3 GO terms that were created as part of the heart development focus project.")
AnnotationAssertion(rdfs:label obo:CL_0010022 "cardiac neuron")
AnnotationAssertion(rdfs:seeAlso obo:CL_0010022 "https://github.com/obophenotype/cell-ontology/pull/1488")
EquivalentClasses(obo:CL_0010022 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000948)))

# Class: obo:CL_0011000 (dorsal horn interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") obo:IAO_0000115 obo:CL_0011000 "A CNS interneuron located in the dorsal horn of the spinal cord.")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0011000 "dorsal spinal cord interneuron")
AnnotationAssertion(rdfs:label obo:CL_0011000 "dorsal horn interneuron")
EquivalentClasses(obo:CL_0011000 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002256)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0011000 obo:CL_0005000)

# Class: obo:CL_0011001 (spinal cord motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") obo:IAO_0000115 obo:CL_0011001 "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.")
AnnotationAssertion(rdfs:label obo:CL_0011001 "spinal cord motor neuron")
EquivalentClasses(obo:CL_0011001 ObjectIntersectionOf(obo:CL_0000100 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002240)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0011001 obo:CL_0000100)

# Class: obo:CL_0011002 (lateral motor column neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") obo:IAO_0000115 obo:CL_0011002 "A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.")
AnnotationAssertion(rdfs:comment obo:CL_0011002 "Need to MIREOT in 'spinal cord lateral column' from Uberon")
AnnotationAssertion(rdfs:label obo:CL_0011002 "lateral motor column neuron")
SubClassOf(obo:CL_0011002 obo:CL_0011001)

# Class: obo:CL_0011003 (magnocellular neurosecretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") Annotation(oboInOwl:hasDbXref "MP:0009467") Annotation(oboInOwl:hasDbXref "PMID:10711808") obo:IAO_0000115 obo:CL_0011003 "A neurosecretory neuron residing mainly in the hypothalamic supraoptic and paraventricular nuclei and in a number of smaller accessory cell groups between these two nuclei, that is capable of secreting the hormones oxytocin or vasopressin, and sometimes both, into the systemic circulation.")
AnnotationAssertion(terms:contributor obo:CL_0011003 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0011003 "ILX:0107463")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011003 "magnocellular neuron")
AnnotationAssertion(rdfs:label obo:CL_0011003 "magnocellular neurosecretory cell")
SubClassOf(obo:CL_0011003 obo:CL_0000165)
SubClassOf(obo:CL_0011003 obo:CL_0000540)
SubClassOf(obo:CL_0011003 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001898))
SubClassOf(obo:CL_0011003 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046879))

# Class: obo:CL_0011004 (lens fiber cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0070307") Annotation(oboInOwl:hasDbXref "GOC:nv") obo:IAO_0000115 obo:CL_0011004 "A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011004 "lens fibre cell")
AnnotationAssertion(rdfs:label obo:CL_0011004 "lens fiber cell")
SubClassOf(obo:CL_0011004 obo:CL_0002222)

# Class: obo:CL_0011005 (GABAergic interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "GOC:nv") Annotation(oboInOwl:hasDbXref "PMID:29724907") obo:IAO_0000115 obo:CL_0011005 "An interneuron that uses GABA as a vesicular neurotransmitter.  These interneurons are inhibitory")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011005 "GABAergic inhibitory interneuron")
AnnotationAssertion(rdfs:comment obo:CL_0011005 "The formal and textual definitions of this term will need to be altered if evidence for non-inhibitory GABA-ergic neurons emerges.")
AnnotationAssertion(rdfs:label obo:CL_0011005 "GABAergic interneuron")
EquivalentClasses(obo:CL_0011005 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))
SubClassOf(obo:CL_0011005 obo:CL_0000498)

# Class: obo:CL_0011006 (Lugaro cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:nv") Annotation(oboInOwl:hasDbXref "PMID:18677503") Annotation(oboInOwl:hasDbXref "PMID:2273099") obo:IAO_0000115 obo:CL_0011006 "A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34194302") oboInOwl:hasRelatedSynonym obo:CL_0011006 "globular cell")
AnnotationAssertion(rdfs:label obo:CL_0011006 "Lugaro cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_0011006 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_0011006 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
SubClassOf(obo:CL_0011006 obo:CL_0000099)
SubClassOf(obo:CL_0011006 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002956))
SubClassOf(obo:CL_0011006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_0011006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537))

# Class: obo:CL_0011007 (paraxial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:11687492") obo:IAO_0000115 obo:CL_0011007 "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011007 "paraxial mesoderm cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011007 "somitic mesoderm cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0011007 "presomitic mesoderm cell")
AnnotationAssertion(rdfs:label obo:CL_0011007 "paraxial cell")
EquivalentClasses(obo:CL_0011007 ObjectIntersectionOf(obo:CL_0000222 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003059)))
SubClassOf(obo:CL_0011007 obo:CL_0000222)

# Class: obo:CL_0011008 (embryonic hemocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:17967061") obo:IAO_0000115 obo:CL_0011008 "A hemocyte derived from the embryonic head mesoderm, which enters the hemolymph as a circulating cell.")
AnnotationAssertion(rdfs:label obo:CL_0011008 "embryonic hemocyte")
SubClassOf(obo:CL_0011008 obo:CL_0000387)

# Class: obo:CL_0011009 (embryonic plasmatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:17967061") obo:IAO_0000115 obo:CL_0011009 "A plasmatocyte derived from the embryonic head mesoderm.")
AnnotationAssertion(rdfs:label obo:CL_0011009 "embryonic plasmatocyte")
SubClassOf(obo:CL_0011009 obo:CL_0000394)
SubClassOf(obo:CL_0011009 obo:CL_0011008)

# Class: obo:CL_0011010 (lateral mesodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:9169844") obo:IAO_0000115 obo:CL_0011010 "A cell derived from the mesoderm that is found at the periphery of the embryo.")
AnnotationAssertion(rdfs:label obo:CL_0011010 "lateral mesodermal cell")
SubClassOf(obo:CL_0011010 obo:CL_0000222)

# Class: obo:CL_0011011 (intermediate mesodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "ISBN:978-0-87969-707-5") obo:IAO_0000115 obo:CL_0011011 "A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate.")
AnnotationAssertion(rdfs:label obo:CL_0011011 "intermediate mesodermal cell")
SubClassOf(obo:CL_0011011 obo:CL_0000222)

# Class: obo:CL_0011012 (neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-9900-7880") obo:IAO_0000115 obo:CL_0011012 "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.")
AnnotationAssertion(rdfs:label obo:CL_0011012 "neural crest cell")
SubClassOf(obo:CL_0011012 obo:CL_0000048)
SubClassOf(obo:CL_0011012 obo:CL_0002321)

# Class: obo:CL_0011013 (motile sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30612620") obo:IAO_0000115 obo:CL_0011013 "A sperm cell that is cabaple of motion (motility).")
AnnotationAssertion(terms:contributor obo:CL_0011013 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011013 "motile sperm cell")
EquivalentClasses(obo:CL_0011013 ObjectIntersectionOf(obo:CL_0000019 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0097722)))

# Class: obo:CL_0011014 (non-motile sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30612620") obo:IAO_0000115 obo:CL_0011014 "A sperm cell that is not cabaple of motion (motility).")
AnnotationAssertion(terms:contributor obo:CL_0011014 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011014 "non-motile sperm cell")
SubClassOf(obo:CL_0011014 obo:CL_0000019)

# Class: obo:CL_0011015 (amoeboid sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17708982") obo:IAO_0000115 obo:CL_0011015 "A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system.")
AnnotationAssertion(terms:contributor obo:CL_0011015 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011015 "amoeboid sperm cell")
SubClassOf(obo:CL_0011015 obo:CL_0011013)

# Class: obo:CL_0011016 (flagellated sperm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30612620") Annotation(oboInOwl:hasDbXref "https://www.lexico.com/en/definition/flagellum") obo:IAO_0000115 obo:CL_0011016 "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion.")
AnnotationAssertion(terms:contributor obo:CL_0011016 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011016 "flagellated sperm cell")
EquivalentClasses(obo:CL_0011016 ObjectIntersectionOf(obo:CL_0011013 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030317)))
SubClassOf(obo:CL_0011016 obo:CL_0011013)

# Class: obo:CL_0011017 (vagal neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22016183") obo:IAO_0000115 obo:CL_0011017 "Cell that is part of the vagal neural crest population. The vagal neural crest arises from the axial level of somites 1-7 and has been described as a hybrid between the head and the trunk populations.")
AnnotationAssertion(terms:contributor obo:CL_0011017 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011017 "vagal neural crest cell")
SubClassOf(obo:CL_0011017 obo:CL_0011012)

# Class: obo:CL_0011018 (lymphoid tissue–inducer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "PMID:19029905") Annotation(oboInOwl:hasDbXref "PMID:21601793") Annotation(oboInOwl:hasDbXref "PMID:27935637") Annotation(oboInOwl:hasDbXref "PMID:29454785") Annotation(oboInOwl:hasDbXref "PMID:9354470") obo:IAO_0000115 obo:CL_0011018 "A group 3 innate lymphoid cell that express ROR gamma t and IL-7R alpha in the absence of lineage markers (e.g. CD3, CD19, B220, CD11c, Gr-1), with the functional ability to interact with mesenchymal cells through lymphotoxin and tumor necrosis factor. Lymphoid tissue-inducer cells are key to the development of lymph nodes and Peyer’s patches.")
AnnotationAssertion(terms:contributor obo:CL_0011018 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011018 "LTi")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011018 "lymphoid tissue inducer cell")
AnnotationAssertion(rdfs:label obo:CL_0011018 "lymphoid tissue–inducer cell")
SubClassOf(obo:CL_0011018 obo:CL_0001071)
SubClassOf(obo:CL_0011018 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869))

# Class: obo:CL_0011019 (mesothelial cell of epicardium)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0011019 "A mesothelial cell that is part of the epicardium.")
AnnotationAssertion(terms:contributor obo:CL_0011019 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011019 "mesothelial cell of epicardium")
EquivalentClasses(obo:CL_0011019 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002348)))
SubClassOf(obo:CL_0011019 obo:CL_0000077)

# Class: obo:CL_0011020 (neural progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23064725") Annotation(oboInOwl:hasDbXref "PMID:30574073") Annotation(oboInOwl:hasDbXref "PMID:37508487") obo:IAO_0000115 obo:CL_0011020 "An undifferentiated cell derived from a neural stem cell, with a limited capacity to self-renew (Dibajnia and Morshead, 2013) and the ability to generate multiple types of lineage-restricted progenitors, contributing to the formation of neurons, astrocytes, and oligodendrocytes.")
AnnotationAssertion(terms:contributor obo:CL_0011020 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011020 "neural progenitor cell")
SubClassOf(obo:CL_0011020 obo:CL_0011026)
SubClassOf(obo:CL_0011020 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000047))

# Class: obo:CL_0011021 (fibroblast of upper back skin)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0011021 "A fibroblast that is part of upper back skin.")
AnnotationAssertion(terms:contributor obo:CL_0011021 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011021 "fibroblast of upper back skin")
EquivalentClasses(obo:CL_0011021 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009015)))
SubClassOf(obo:CL_0011021 obo:CL_0011022)

# Class: obo:CL_0011022 (fibroblast of skin of back)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0011022 "A fibroblast that is part of skin of back.")
AnnotationAssertion(terms:contributor obo:CL_0011022 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011022 "fibroblast of skin of back")
EquivalentClasses(obo:CL_0011022 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001068)))
SubClassOf(obo:CL_0011022 obo:CL_0000057)

# Class: obo:CL_0011023 (CD25+ mast cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0011023 "A mast cell that is CD25+.")
AnnotationAssertion(terms:contributor obo:CL_0011023 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011023 "CD25+ neoplastic mast cell")
AnnotationAssertion(rdfs:comment obo:CL_0011023 "Mast cells do not normally express CD25, but neoplastic mast cells may be CD25-positive.")
AnnotationAssertion(rdfs:label obo:CL_0011023 "CD25+ mast cell")
EquivalentClasses(obo:CL_0011023 ObjectIntersectionOf(obo:CL_0001063 ObjectSomeValuesFrom(obo:RO_0001000 obo:CL_0000097) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
SubClassOf(obo:CL_0011023 obo:CL_0001063)

# Class: obo:CL_0011024 (double negative T regulatory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16285891") obo:IAO_0000115 obo:CL_0011024 "A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation.")
AnnotationAssertion(terms:contributor obo:CL_0011024 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011024 "CD4-negative, CD8-negative, alpha-beta regulatory T cells")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011024 "DN Treg")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011024 "double-negative alpha-beta regulatory T cell")
AnnotationAssertion(rdfs:label obo:CL_0011024 "double negative T regulatory cell")
EquivalentClasses(obo:CL_0011024 ObjectIntersectionOf(obo:CL_0002489 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
SubClassOf(obo:CL_0011024 obo:CL_0002489)

# Class: obo:CL_0011025 (exhausted T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26544946") obo:IAO_0000115 obo:CL_0011025 "An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential.")
AnnotationAssertion(terms:contributor obo:CL_0011025 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011025 "Tex cell")
AnnotationAssertion(rdfs:label obo:CL_0011025 "exhausted T cell")
SubClassOf(obo:CL_0011025 obo:CL_0000911)

# Class: obo:CL_0011026 (progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:978-1-62808-994-3") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/B978-0-12-409503-8.00002-0") obo:IAO_0000115 obo:CL_0011026 "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.")
AnnotationAssertion(terms:contributor obo:CL_0011026 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(rdfs:label obo:CL_0011026 "progenitor cell")
EquivalentClasses(obo:CL_0011026 ObjectIntersectionOf(obo:CL_0011115 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000034)))
SubClassOf(obo:CL_0011026 obo:CL_0011115)

# Class: obo:CL_0011027 (skeletal muscle fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28369879") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6164-0667") obo:IAO_0000115 obo:CL_0011027 "Any fibroblast that is part of skeletal muscle tissue.")
AnnotationAssertion(terms:contributor obo:CL_0011027 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011027 "skeleton muscle fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0011027 "skeletal muscle fibroblast")
EquivalentClasses(obo:CL_0011027 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134)))
SubClassOf(obo:CL_0011027 obo:CL_0000057)

# Class: obo:CL_0011028 (olfactory ensheathing cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22456085") obo:IAO_0000115 obo:CL_0011028 "A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons.")
AnnotationAssertion(terms:contributor obo:CL_0011028 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0011028 "BTO:0002771")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011028 "OEC")
AnnotationAssertion(rdfs:label obo:CL_0011028 "olfactory ensheathing cell")
SubClassOf(obo:CL_0011028 obo:CL_0000125)

# Class: obo:CL_0011029 (cnidocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/Cnidocyte") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2825-0621") obo:IAO_0000115 obo:CL_0011029 "An explosive cell containing one giant secretory organelle called a cnidocyst (also known as a cnida (plural cnidae) or nematocyst) that contains a toxin responsible for the stings delivered by a cnidarian to other organisms. Cnidae are used to capture prey and as a defense against predators. The presence of cnidocytes defines the phylum Cnidaria (corals, sea anemones, hydrae, jellyfish, etc.).")
AnnotationAssertion(terms:contributor obo:CL_0011029 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011029 "cnidoblast")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011029 "nematocyte")
AnnotationAssertion(rdfs:label obo:CL_0011029 "cnidocyte")
SubClassOf(obo:CL_0011029 obo:CL_0000151)
SubClassOf(obo:CL_0011029 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042151))
SubClassOf(obo:CL_0011029 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6073))

# Class: obo:CL_0011030 (dermal microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0004574") Annotation(oboInOwl:hasDbXref "CL:patterns/cellPartOfAnatomicalEntity") obo:IAO_0000115 obo:CL_0011030 "Any microvascular endothelial cell that is part of the dermis.")
AnnotationAssertion(terms:contributor obo:CL_0011030 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011030 "DMEC cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011030 "dermal microvascular endothelium cell")
AnnotationAssertion(rdfs:label obo:CL_0011030 "dermal microvascular endothelial cell")
EquivalentClasses(obo:CL_0011030 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067)))

# Class: obo:CL_0011031 (monocyte-derived dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0002900") Annotation(oboInOwl:hasDbXref "PMID:30719026") Annotation(oboInOwl:hasDbXref "PMID:32733468") obo:IAO_0000115 obo:CL_0011031 "A dendritic cell that develops from a monocyte.")
AnnotationAssertion(terms:contributor obo:CL_0011031 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011031 "MDDC cell")
AnnotationAssertion(rdfs:label obo:CL_0011031 "monocyte-derived dendritic cell")
SubClassOf(obo:CL_0011031 obo:CL_0000782)
SubClassOf(obo:CL_0011031 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))

# Class: obo:CL_0011032 (lysosome-rich enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31474562") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-1009-339X") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2244-7917") obo:IAO_0000115 obo:CL_0011032 "An enterocyte that possesses a large supranuclear vacuolar system that preferentially internalizes dietary protein via receptor-mediated and fluid-phase endocytosis for intracellular digestion and trans-cellular transport. In zebrafish these cells are located in the posterior region of the mid intestine throughout life. In mammals they are found in the ileum pre-weaning and later are replaced by mature enterocytes.")
AnnotationAssertion(terms:contributor obo:CL_0011032 <https://orcid.org/0000-0001-5208-3432>)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0011032 "vacuolated enterocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011032 "LRE")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasRelatedSynonym obo:CL_0011032 "early enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33290721") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-9610-7627") oboInOwl:hasRelatedSynonym obo:CL_0011032 "immature enterocyte")
AnnotationAssertion(rdfs:label obo:CL_0011032 "lysosome-rich enterocyte")
SubClassOf(obo:CL_0011032 obo:CL_0000584)

# Class: obo:CL_0011100 (galanergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:23159249") Annotation(oboInOwl:hasDbXref "ZFIN:CVS") Annotation(oboInOwl:hasDbXref "ZFIN:YB") obo:IAO_0000115 obo:CL_0011100 "Neuron that secretes the neurotransmitter galanin.")
AnnotationAssertion(rdfs:label obo:CL_0011100 "galanergic neuron")
SubClassOf(obo:CL_0011100 obo:CL_0000540)

# Class: obo:CL_0011101 (chorionic trophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") obo:IAO_0000115 obo:CL_0011101 "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.")
AnnotationAssertion(rdfs:label obo:CL_0011101 "chorionic trophoblast cell")
EquivalentClasses(obo:CL_0011101 ObjectIntersectionOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003124)))
SubClassOf(obo:CL_0011101 obo:CL_0000351)

# Class: obo:CL_0011102 (parasympathetic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "isbn:0080923437") obo:IAO_0000115 obo:CL_0011102 "Parasympathetic neurons are part of the parasympathetic nervous sysem and the cell bodies lie in the brain and sacral region of the spinal cord. The neurons are mainly cholinergic.")
AnnotationAssertion(rdfs:label obo:CL_0011102 "parasympathetic neuron")
SubClassOf(obo:CL_0011102 obo:CL_0000107)

# Class: obo:CL_0011103 (sympathetic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "isbn:0080923437") obo:IAO_0000115 obo:CL_0011103 "Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides.")
AnnotationAssertion(rdfs:label obo:CL_0011103 "sympathetic neuron")
SubClassOf(obo:CL_0011103 obo:CL_0000107)

# Class: obo:CL_0011104 (interplexiform cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:12771169") obo:IAO_0000115 obo:CL_0011104 "A type of interneuron in the retinal inner nuclear layer which
carries information from the inner plexiform layer and the outer
plexiform layer.")
AnnotationAssertion(rdfs:comment obo:CL_0011104 "Need to MIREOT retinal inner nuclear layer (part of)")
AnnotationAssertion(rdfs:label obo:CL_0011104 "interplexiform cell")
SubClassOf(obo:CL_0011104 obo:CL_0000099)
SubClassOf(obo:CL_0011104 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001791))

# Class: obo:CL_0011105 (dopamanergic interplexiform cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:12771169") obo:IAO_0000115 obo:CL_0011105 "A type of interneuron in the retinal inner nuclear layer which
carries information from the inner plexiform layer and the outer
plexiform layer, using dopamine.")
AnnotationAssertion(rdfs:comment obo:CL_0011105 "This type of cell is found in Danio rerio.")
AnnotationAssertion(rdfs:label obo:CL_0011105 "dopamanergic interplexiform cell")
EquivalentClasses(obo:CL_0011105 ObjectIntersectionOf(obo:CL_0011104 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527)))

# Class: obo:CL_0011106 (GABAnergic interplexiform cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:12771169") obo:IAO_0000115 obo:CL_0011106 "A type of interneuron in the retinal inner nuclear layer which
carries information from the inner plexiform layer and the outer
plexiform layer using GABA.")
AnnotationAssertion(rdfs:comment obo:CL_0011106 "This type of cell is found in many mammals.")
AnnotationAssertion(rdfs:label obo:CL_0011106 "GABAnergic interplexiform cell")
EquivalentClasses(obo:CL_0011106 ObjectIntersectionOf(obo:CL_0011104 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_0011107 (obsolete Muller cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:21911394") obo:IAO_0000115 obo:CL_0011107 "OBSOLETE: Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0011107 obo:CL_0000636)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011107 "Muller glia")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011107 "Müller cell")
AnnotationAssertion(rdfs:comment obo:CL_0011107 "Term was duplicated, use CL:0000636 instead")
AnnotationAssertion(rdfs:label obo:CL_0011107 "obsolete Muller cell")
AnnotationAssertion(owl:deprecated obo:CL_0011107 "true"^^xsd:boolean)

# Class: obo:CL_0011108 (colon epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") obo:IAO_0000115 obo:CL_0011108 "Epithelial cell that is part of the colon epithelium.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011108 "colonic epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0011108 "colon epithelial cell")
EquivalentClasses(obo:CL_0011108 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))

# Class: obo:CL_0011109 (hypocretin-secreting neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:23848055") obo:IAO_0000115 obo:CL_0011109 "A neuron that releases hypocretin as a neurotransmitter.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011109 "orexin")
AnnotationAssertion(rdfs:label obo:CL_0011109 "hypocretin-secreting neuron")
EquivalentClasses(obo:CL_0011109 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061585)))
SubClassOf(obo:CL_0011109 obo:CL_0000540)

# Class: obo:CL_0011110 (histaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:22677810") obo:IAO_0000115 obo:CL_0011110 "Neuron that secretes histamine.")
AnnotationAssertion(rdfs:label obo:CL_0011110 "histaminergic neuron")
EquivalentClasses(obo:CL_0011110 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061538)))
SubClassOf(obo:CL_0011110 obo:CL_0000540)

# Class: obo:CL_0011111 (hypothalamic gonadotropin-releasing hormone neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:20807514") Annotation(oboInOwl:hasDbXref "PMID:21828096") Annotation(oboInOwl:hasDbXref "PMID:26053743") Annotation(oboInOwl:hasDbXref "PMID:34128468") Annotation(oboInOwl:hasDbXref "PMID:35067985") obo:IAO_0000115 obo:CL_0011111 "a specialized neuroendocrine cell that synthesizes and secretes GnRH decapeptide, a key regulator of reproductive function. It originates from the olfactory placode during embryonic development and migrates into the forebrain where it localises predominantly in the hypothalamus and in humans, in extrahypothalamic regions like the basal ganglia (Skrapits et al., 2021). This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. It expresses receptor subunits required for AMPA, NMDA, and kainate receptor signaling and may use glutamate as a neurotransmitter in recurrent collateral innervation.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011111 "GnRH neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011111 "GnRH-secreting neuron")
AnnotationAssertion(rdfs:label obo:CL_0011111 "hypothalamic gonadotropin-releasing hormone neuron")
SubClassOf(obo:CL_0011111 obo:CL_0000165)
SubClassOf(obo:CL_0011111 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001890))
SubClassOf(obo:CL_0011111 ObjectSomeValuesFrom(obo:RO_0002596 obo:GO_0032274))

# Class: obo:CL_0011112 (obsolete magnocellular neurosecretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:10711808") obo:IAO_0000115 obo:CL_0011112 "OBSOLETE: Neurons part of the hypothalamic supraoptic and paraventricular nuclei that secrete the hormones, oxytocin and vasopressin into the systemic circulation from the posterior pituitary gland.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0011112 obo:CL_0011003)
AnnotationAssertion(rdfs:comment obo:CL_0011112 "Duplicated term, please see CL:0011003 instead")
AnnotationAssertion(rdfs:label obo:CL_0011112 "obsolete magnocellular neurosecretory cell")
AnnotationAssertion(owl:deprecated obo:CL_0011112 "true"^^xsd:boolean)

# Class: obo:CL_0011113 (spiral ganglion neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") obo:IAO_0000115 obo:CL_0011113 "Neuron found in the spiral ganglion.")
AnnotationAssertion(rdfs:label obo:CL_0011113 "spiral ganglion neuron")
EquivalentClasses(obo:CL_0011113 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000395)))
SubClassOf(obo:CL_0011113 obo:CL_0000540)

# Class: obo:CL_0011114 (segmented neutrophil of bone marrow)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11138622") Annotation(oboInOwl:hasDbXref "PMID:15514007") obo:IAO_0000115 obo:CL_0011114 "A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface.")
AnnotationAssertion(rdfs:label obo:CL_0011114 "segmented neutrophil of bone marrow")
SubClassOf(obo:CL_0011114 obo:CL_0000096)
SubClassOf(obo:CL_0011114 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371))
SubClassOf(obo:CL_0011114 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012))
SubClassOf(obo:CL_0011114 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483))

# Class: obo:CL_0011115 (precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") obo:IAO_0000115 obo:CL_0011115 "A cell that, by division or terminal differentiation, can give rise to other cell types.")
AnnotationAssertion(rdfs:comment obo:CL_0011115 "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.")
AnnotationAssertion(rdfs:label obo:CL_0011115 "precursor cell")
EquivalentClasses(obo:CL_0011115 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030154)))

# Class: obo:CL_0012000 (astrocyte of the forebrain)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0012000 "An astrocyte of the forebrain.")
AnnotationAssertion(terms:contributor obo:CL_0012000 <https://orcid.org/0000-0002-3837-8864>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0012000 "forebrain astrocyte")
AnnotationAssertion(rdfs:label obo:CL_0012000 "astrocyte of the forebrain")
EquivalentClasses(obo:CL_0012000 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001890)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0012000 obo:CL_0000127)

# Class: obo:CL_0012001 (neuron of the forebrain)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0012001 "A CNS neuron of the forebrain.")
AnnotationAssertion(terms:contributor obo:CL_0012001 <https://orcid.org/0000-0002-3837-8864>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0012001 "forebrain neuron")
AnnotationAssertion(rdfs:label obo:CL_0012001 "neuron of the forebrain")
EquivalentClasses(obo:CL_0012001 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001890)))

# Class: obo:CL_0013000 (forebrain radial glial cell)

AnnotationAssertion(rdfs:label obo:CL_0013000 "forebrain radial glial cell"@en)
EquivalentClasses(obo:CL_0013000 ObjectIntersectionOf(obo:CL_0000681 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001890)))
SubClassOf(obo:CL_0013000 obo:CL_0000681)

# Class: obo:CL_0015000 (cranial motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFIN:CVS") obo:IAO_0000115 obo:CL_0015000 "Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0015000 "PMID:14699587")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0015000 "cranial motoneuron")
AnnotationAssertion(rdfs:label obo:CL_0015000 "cranial motor neuron")
SubClassOf(obo:CL_0015000 obo:CL_0000100)

# Class: obo:CL_0017000 (pulmonary ionocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30069044") Annotation(oboInOwl:hasDbXref "PMID:30069046") obo:IAO_0000115 obo:CL_0017000 "An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice.")
AnnotationAssertion(terms:contributor obo:CL_0017000 <https://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(rdfs:label obo:CL_0017000 "pulmonary ionocyte")
EquivalentClasses(obo:CL_0017000 ObjectIntersectionOf(obo:CL_0005006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000115)))
SubClassOf(obo:CL_0017000 obo:CL_0005006)

# Class: obo:CL_0017001 (splanchnic mesodermal cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0017001 "A mesodermal cell that is part of the splanchnic layer of lateral plate mesoderm.")
AnnotationAssertion(terms:contributor obo:CL_0017001 <https://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(rdfs:label obo:CL_0017001 "splanchnic mesodermal cell")
SubClassOf(obo:CL_0017001 obo:CL_0011010)
SubClassOf(obo:CL_0017001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004872))

# Class: obo:CL_0017002 (prostate neuroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33842835") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0001-7772-9578") obo:IAO_0000115 obo:CL_0017002 "A neuroendocrine cell that is part of the prostate epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0017002 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0017002 "neuroendocrine cell of prostate epithelium")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0017002 "neuroendocrine cell of the prostate")
AnnotationAssertion(rdfs:label obo:CL_0017002 "prostate neuroendocrine cell")
EquivalentClasses(obo:CL_0017002 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000428)))

# Class: obo:CL_0017003 (epithelial cell of prostatic urethra)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30566875") obo:IAO_0000115 obo:CL_0017003 "An epithelial cell that is part of the prostatic urethra.")
AnnotationAssertion(terms:contributor obo:CL_0017003 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(rdfs:label obo:CL_0017003 "epithelial cell of prostatic urethra")
EquivalentClasses(obo:CL_0017003 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001335)))

# Class: obo:CL_0017004 (telocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D000067170") Annotation(oboInOwl:hasDbXref "PMID:20367664") Annotation(oboInOwl:hasDbXref "PMID:28714595") Annotation(oboInOwl:hasDbXref "PMID:31311805") Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/Telocyte") obo:IAO_0000115 obo:CL_0017004 "A supportive cell with a small, oval-shaped body and one to five telopodes. Telopodes are cytoplasmic protrusions from tens to hundreds of micrometers long and mostly below 0.2 microns of caliber.")
AnnotationAssertion(terms:contributor obo:CL_0017004 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20367664") oboInOwl:hasNarrowSynonym obo:CL_0017004 "interstitial Cajal cell-like cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20367664") oboInOwl:hasNarrowSynonym obo:CL_0017004 "interstitial Cajal-like cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20367664") oboInOwl:hasRelatedSynonym obo:CL_0017004 "ICLC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31311805") oboInOwl:hasRelatedSynonym obo:CL_0017004 "interstitial neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1016/B978-0-12-818561-2.00001-1>) rdfs:comment obo:CL_0017004 "Telocytes manage to develop complex networks in almost all organs of the human body. Although staining positively for vimentin antibody, some uncertainty still persists over the mesenchymal origin of these cells.")
AnnotationAssertion(rdfs:label obo:CL_0017004 "telocyte")
SubClassOf(obo:CL_0017004 obo:CL_0002320)
SubClassOf(obo:CL_0017004 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0120327))

# Class: obo:CL_0017005 (lymphoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NCIT:C13013") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0001-9990-8331") obo:IAO_0000115 obo:CL_0017005 "A lymphocyte that has gotten larger after being stimulated by an antigen.")
AnnotationAssertion(terms:contributor obo:CL_0017005 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:date obo:CL_0017005 "2022-08-17T14:20:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0017005 "BTO:0000772")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0017005 "EFO:0000572")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0017005 "FMA:83030")
AnnotationAssertion(rdfs:label obo:CL_0017005 "lymphoblast")
SubClassOf(obo:CL_0017005 obo:CL_0000542)
SubClassOf(obo:CL_0017005 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0046649))

# Class: obo:CL_0017006 (B-lymphoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "EFO:0005293") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2825-0621") obo:IAO_0000115 obo:CL_0017006 "A lymphocyte of B lineage that has gotten larger after being stimulated by an antigen.")
AnnotationAssertion(terms:contributor obo:CL_0017006 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:date obo:CL_0017006 "2022-08-17T14:30:32Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0017006 "EFO:0005293")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0017006 "FMA:83031")
AnnotationAssertion(rdfs:label obo:CL_0017006 "B-lymphoblast")
SubClassOf(obo:CL_0017006 obo:CL_0000945)
SubClassOf(obo:CL_0017006 obo:CL_0017005)

# Class: obo:CL_0017009 (Axl+ dendritic cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28428369") Annotation(oboInOwl:hasDbXref "PMID:29221729") Annotation(oboInOwl:hasDbXref "PMID:31156637") obo:IAO_0000115 obo:CL_0017009 "A human dendritic cell that expresses the AXL and SIGLEC6 genes.")
AnnotationAssertion(terms:contributor obo:CL_0017009 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:date obo:CL_0017009 "2022-08-25T14:18:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0017009 "AS DC, human")
AnnotationAssertion(rdfs:label obo:CL_0017009 "Axl+ dendritic cell, human")
SubClassOf(obo:CL_0017009 obo:CL_0001056)
SubClassOf(obo:CL_0017009 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_0017009 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_O43699))
SubClassOf(obo:CL_0017009 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P30530))

# Class: obo:CL_0017010 (hillock cell of urethral epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0001-7772-9578>) Annotation(oboInOwl:hasDbXref "PMID:30566875") obo:IAO_0000115 obo:CL_0017010 "A hillock cell that is part of the urethra.")
AnnotationAssertion(terms:contributor obo:CL_0017010 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:date obo:CL_0017010 "2022-10-13T13:51:35Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0017010 "hillock cell of urethra")
AnnotationAssertion(rdfs:label obo:CL_0017010 "hillock cell of urethral epithelium")
EquivalentClasses(obo:CL_0017010 ObjectIntersectionOf(obo:CL_4030024 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000057)))

# Class: obo:CL_0017011 (hillock cell of prostatic urethral epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0001-7772-9578>) Annotation(oboInOwl:hasDbXref "PMID:30566875") obo:IAO_0000115 obo:CL_0017011 "A hillock cell that is part of the prostatic urethra.")
AnnotationAssertion(terms:contributor obo:CL_0017011 <http://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:date obo:CL_0017011 "2022-10-13T13:58:15Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0017011 "hillock cell of prostatic urethra")
AnnotationAssertion(rdfs:label obo:CL_0017011 "hillock cell of prostatic urethral epithelium")
EquivalentClasses(obo:CL_0017011 ObjectIntersectionOf(obo:CL_4030024 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001335)))

# Class: obo:CL_0017500 (neutrophillic cytoplasm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0017500 "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain.")
AnnotationAssertion(terms:contributor obo:CL_0017500 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017500 "2010-05-25T01:36:34Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017500 "neutrophillic cytoplasm")
EquivalentClasses(obo:CL_0017500 ObjectIntersectionOf(obo:GO_0005737 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070046)))

# Class: obo:CL_0017501 (obsolete lobed nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017501 "Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0017501 <https://github.com/obophenotype/cell-ontology/issues/734>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0017501 obo:GO_0098537)
AnnotationAssertion(terms:contributor obo:CL_0017501 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017501 "2009-12-22T03:54:43Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0017501 "Obsoleted because duplicate with GO term.")
AnnotationAssertion(rdfs:label obo:CL_0017501 "obsolete lobed nucleus")
AnnotationAssertion(owl:deprecated obo:CL_0017501 "true"^^xsd:boolean)

# Class: obo:CL_0017502 (acidophilic cytoplasm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0017502 "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain.")
AnnotationAssertion(terms:contributor obo:CL_0017502 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017502 "2009-12-22T04:23:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0017502 "eosinophilic")
AnnotationAssertion(rdfs:label obo:CL_0017502 "acidophilic cytoplasm")
EquivalentClasses(obo:CL_0017502 ObjectIntersectionOf(obo:GO_0005737 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002418)))

# Class: obo:CL_0017503 (basophilic cytoplasm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017503 "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions.")
AnnotationAssertion(terms:contributor obo:CL_0017503 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017503 "2009-12-22T04:24:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017503 "basophilic cytoplasm")
EquivalentClasses(obo:CL_0017503 ObjectIntersectionOf(obo:GO_0005737 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002094)))
SubClassOf(obo:CL_0017503 obo:GO_0005737)

# Class: obo:CL_0017504 (polychromatophilic cytoplasm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017504 "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions.")
AnnotationAssertion(terms:contributor obo:CL_0017504 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017504 "2009-12-28T04:25:23Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017504 "polychromatophilic cytoplasm")
EquivalentClasses(obo:CL_0017504 ObjectIntersectionOf(obo:GO_0005737 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070047)))

# Class: obo:CL_0017505 (obsolete increased nucleus size)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017505 "OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0017505 <https://github.com/obophenotype/cell-ontology/issues/2251>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_0017505 obo:PATO_0040072)
AnnotationAssertion(terms:contributor obo:CL_0017505 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017505 "2009-12-23T10:53:24Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:comment obo:CL_0017505 "This class was a phenotype, not a cell type.")
AnnotationAssertion(rdfs:label obo:CL_0017505 "obsolete increased nucleus size")
AnnotationAssertion(owl:deprecated obo:CL_0017505 "true"^^xsd:boolean)

# Class: obo:CL_0017506 (banded nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017506 "A concave nuclear shape where the nucleus is indented to more than half the distance to the farthest nuclear margin, but in no area is the chromatin condensed to a single filament.")
AnnotationAssertion(terms:contributor obo:CL_0017506 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017506 "2009-12-23T02:18:43Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017506 "banded nucleus")
SubClassOf(obo:CL_0017506 obo:GO_0005634)

# Class: obo:CL_0017507 (reniform nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017507 "A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin.")
AnnotationAssertion(terms:contributor obo:CL_0017507 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017507 "2009-12-23T02:31:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017507 "reniform nucleus")
EquivalentClasses(obo:CL_0017507 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001871)))
SubClassOf(obo:CL_0017507 obo:GO_0005634)

# Class: obo:CL_0017508 (cartwheel heterochromatin)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0017508 "Heterochromatin that is arranged in a carthwheel pattern.")
AnnotationAssertion(terms:contributor obo:CL_0017508 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0017508 "2009-12-28T04:28:35Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0017508 "cartwheel heterochromatin")
SubClassOf(obo:CL_0017508 obo:GO_0000792)

# Class: obo:CL_0017509 (alobate nucleus)

AnnotationAssertion(rdfs:label obo:CL_0017509 "alobate nucleus"@en)
EquivalentClasses(obo:CL_0017509 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002506)))
SubClassOf(obo:CL_0017509 obo:GO_0005634)

# Class: obo:CL_0019001 (tracheobronchial serous cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0019001 "Any serous secreting cell that is part of the tracheobronchial epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0019001 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019001 "2020-05-07T16:03:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019001 "serous cell of tracheobronchial tree")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0019001 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0019001 "tracheobronchial serous cell"@en)
EquivalentClasses(obo:CL_0019001 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007196)))

# Class: obo:CL_0019002 (tracheobronchial chondrocyte)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0019002 "Any chondrocyte that is part of the tracheobronchial tree.")
AnnotationAssertion(terms:contributor obo:CL_0019002 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019002 "2020-05-07T17:29:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019002 "chondrocyte of tracheobronchial tree")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0019002 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0019002 "tracheobronchial chondrocyte"@en)
EquivalentClasses(obo:CL_0019002 ObjectIntersectionOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007196)))

# Class: obo:CL_0019003 (tracheobronchial goblet cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_0019003 "Any goblet cell that is part of the tracheobronchial epithelium.")
AnnotationAssertion(terms:contributor obo:CL_0019003 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019003 "2020-05-07T18:14:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019003 "goblet cell of tracheobronchial tree")
AnnotationAssertion(oboInOwl:inSubset obo:CL_0019003 cl:added_for_HCA)
AnnotationAssertion(rdfs:label obo:CL_0019003 "tracheobronchial goblet cell"@en)
EquivalentClasses(obo:CL_0019003 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008397)))

# Class: obo:CL_0019015 (lung parenchyma resident eosinophil)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27548519") obo:IAO_0000115 obo:CL_0019015 "An eosinophil with a ring-shaped nucleus that is resident in the lung parenchyma. In mouse, lung parenchyma resident eosinophils are IL-5-independent Siglec-F(intermediate) CD62L+ CD101(low). In human, they are Siglec-8+ CD62L+ IL-3R(low).")
AnnotationAssertion(terms:contributor obo:CL_0019015 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019015 "2020-05-26T09:42:19Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27548519") oboInOwl:hasExactSynonym obo:CL_0019015 "lung-resident eosinophil")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27548519") oboInOwl:hasExactSynonym obo:CL_0019015 "rEos")
AnnotationAssertion(rdfs:label obo:CL_0019015 "lung parenchyma resident eosinophil"@en)
EquivalentClasses(obo:CL_0019015 ObjectIntersectionOf(obo:CL_0000774 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008946)))

# Class: obo:CL_0019017 (lymphatic vessel smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15109561") obo:IAO_0000115 obo:CL_0019017 "A smooth muscle cell that is part of any lymphatic vessel.")
AnnotationAssertion(terms:contributor obo:CL_0019017 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019017 "2020-07-21T12:29:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019017 "smooth muscle cell of lymphatic vessel")
AnnotationAssertion(rdfs:label obo:CL_0019017 "lymphatic vessel smooth muscle cell"@en)
EquivalentClasses(obo:CL_0019017 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001473)))

# Class: obo:CL_0019018 (blood vessel smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9108778") obo:IAO_0000115 obo:CL_0019018 "A smooth muscle cell that is part of any blood vessel.")
AnnotationAssertion(terms:contributor obo:CL_0019018 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019018 "2020-07-21T12:42:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019018 "smooth muscle cell of blood vessel")
AnnotationAssertion(rdfs:label obo:CL_0019018 "blood vessel smooth muscle cell"@en)
EquivalentClasses(obo:CL_0019018 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981)))

# Class: obo:CL_0019019 (tracheobronchial smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10853867") obo:IAO_0000115 obo:CL_0019019 "A smooth muscle cell that is part of the tracheobronchial tree.")
AnnotationAssertion(terms:contributor obo:CL_0019019 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019019 "2020-07-21T12:50:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0019019 "smooth muscle cell of tracheobronchial tree")
AnnotationAssertion(rdfs:label obo:CL_0019019 "tracheobronchial smooth muscle cell"@en)
EquivalentClasses(obo:CL_0019019 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007196)))

# Class: obo:CL_0019020 (extrahepatic cholangiocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23720296") obo:IAO_0000115 obo:CL_0019020 "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes.")
AnnotationAssertion(terms:contributor obo:CL_0019020 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019020 "2020-09-03T12:24:24Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23720296") oboInOwl:hasExactSynonym obo:CL_0019020 "large bile duct cholangiocyte")
AnnotationAssertion(rdfs:label obo:CL_0019020 "extrahepatic cholangiocyte"@en)
EquivalentClasses(obo:CL_0019020 ObjectIntersectionOf(obo:CL_1000488 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004822)))

# Class: obo:CL_0019021 (endothelial cell of periportal hepatic sinusoid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27423426") obo:IAO_0000115 obo:CL_0019021 "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid.")
AnnotationAssertion(terms:contributor obo:CL_0019021 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019021 "2020-09-09T13:56:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0019021 "EFO:0010705")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28287163") oboInOwl:hasExactSynonym obo:CL_0019021 "periportal LSEC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30348985") oboInOwl:hasExactSynonym obo:CL_0019021 "periportal hepatic sinusoidal endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_0019021 "endothelial cell of periportal hepatic sinusoid"@en)
EquivalentClasses(obo:CL_0019021 ObjectIntersectionOf(obo:CL_1000398 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001279)))

# Class: obo:CL_0019022 (endothelial cell of pericentral hepatic sinusoid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27423426") obo:IAO_0000115 obo:CL_0019022 "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid.")
AnnotationAssertion(terms:contributor obo:CL_0019022 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019022 "2020-09-10T12:38:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0019022 "EFO:0010706")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30348985") oboInOwl:hasExactSynonym obo:CL_0019022 "central venous hepatic sinusoidal endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28287163") oboInOwl:hasExactSynonym obo:CL_0019022 "pericentral LSEC")
AnnotationAssertion(rdfs:label obo:CL_0019022 "endothelial cell of pericentral hepatic sinusoid"@en)
EquivalentClasses(obo:CL_0019022 ObjectIntersectionOf(obo:CL_1000398 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0006841)))

# Class: obo:CL_0019026 (periportal region hepatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") obo:IAO_0000115 obo:CL_0019026 "Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism.")
AnnotationAssertion(terms:contributor obo:CL_0019026 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019026 "2020-10-12T10:29:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") oboInOwl:hasExactSynonym obo:CL_0019026 "periportal hepatocyte")
AnnotationAssertion(rdfs:label obo:CL_0019026 "periportal region hepatocyte"@en)
EquivalentClasses(obo:CL_0019026 ObjectIntersectionOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8400006)))

# Class: obo:CL_0019028 (midzonal region hepatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") obo:IAO_0000115 obo:CL_0019028 "Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule.")
AnnotationAssertion(terms:contributor obo:CL_0019028 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019028 "2020-10-12T10:57:40Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") oboInOwl:hasExactSynonym obo:CL_0019028 "midzonal hepatocyte")
AnnotationAssertion(rdfs:label obo:CL_0019028 "midzonal region hepatocyte"@en)
EquivalentClasses(obo:CL_0019028 ObjectIntersectionOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8400008)))

# Class: obo:CL_0019029 (centrilobular region hepatocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") obo:IAO_0000115 obo:CL_0019029 "Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs.")
AnnotationAssertion(terms:contributor obo:CL_0019029 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019029 "2020-10-12T11:03:51Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29763190") oboInOwl:hasExactSynonym obo:CL_0019029 "centrilobular hepatocyte")
AnnotationAssertion(rdfs:label obo:CL_0019029 "centrilobular region hepatocyte"@en)
EquivalentClasses(obo:CL_0019029 ObjectIntersectionOf(obo:CL_0000182 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8400007)))

# Class: obo:CL_0019031 (intestine goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1996606") Annotation(oboInOwl:hasDbXref "PMID:24942678") Annotation(oboInOwl:hasDbXref "PMID:33484640") obo:IAO_0000115 obo:CL_0019031 "Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3.")
AnnotationAssertion(terms:contributor obo:CL_0019031 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019031 "2020-10-14T14:59:07Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1996606") oboInOwl:hasExactSynonym obo:CL_0019031 "intestinal goblet cell")
AnnotationAssertion(rdfs:label obo:CL_0019031 "intestine goblet cell"@en)
EquivalentClasses(obo:CL_0019031 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)))
SubClassOf(obo:CL_0019031 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4047017))

# Class: obo:CL_0019032 (intestinal tuft cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") Annotation(oboInOwl:hasDbXref "PMID:29714721") Annotation(oboInOwl:hasDbXref "PMID:35237268") Annotation(oboInOwl:hasDbXref "PMID:39358509") obo:IAO_0000115 obo:CL_0019032 "A tuft cell that is part of the intestinal epithelium, characterized by a distinctive apical tuft and lateral cytospinules connecting to neighbouring cells. This cell senses luminal stimuli via taste receptors and succinate signalling, initiating type 2 immune responses through the secretion of interleukin-25 while modulating epithelial regeneration through prostaglandin synthesis. It expresses key molecular markers such as doublecortin-like kinase 1 (DCLK1) in mice (Hendel et al., 2022), and KIT proto-oncogene in humans (Huang et al., 2024). Developed from intestinal crypt stem cells, this cell requires transcription factor POU2F3 for its development.")
AnnotationAssertion(terms:contributor obo:CL_0019032 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019032 "2020-10-15T12:47:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") oboInOwl:hasExactSynonym obo:CL_0019032 "intestinal brush cell")
AnnotationAssertion(rdfs:label obo:CL_0019032 "intestinal tuft cell"@en)
EquivalentClasses(obo:CL_0019032 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)))
SubClassOf(obo:CL_0019032 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002250))

# Class: obo:CL_0020000 (gut mesenchymal lymphoid tissue organizer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31324739") Annotation(oboInOwl:hasDbXref "PMID:33707780") Annotation(oboInOwl:hasDbXref "PMID:34046914") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_0020000 "A mesenchymal stromal cell found in the gut during development, and interacts with lymphoid tissue inducer (LTi) cells to drive secondary lymphoid organ formation (Prados et al., 2021). It expresses LTβR, PDGFRα, and VCAM, and upon activation secretes chemokines(e.g. CXCL13) and cytokines to organise lymphoid tissue architecture and recruit immune cells in both mice and humans (Denton el al., 2019; Elmentaite et al., 2021). As a multipotent progenitor, an mLTo cell differentiates into adult stromal subsets, including fibroblastic reticular cells (FRCs) (Prados et al., 2021), and its descendants persist in the adult gut-associated lymphoid tissues to maintain immune homeostasis(Denton el al., 2019; Lütge et al., 2021).")
AnnotationAssertion(terms:contributor obo:CL_0020000 "https://orcid.org/0009-0000-8480-9277")
AnnotationAssertion(terms:date obo:CL_0020000 "2025-01-27T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31201308") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020000 "gut mLTo cell")
AnnotationAssertion(rdfs:label obo:CL_0020000 "gut mesenchymal lymphoid tissue organizer cell")
SubClassOf(obo:CL_0020000 obo:CL_0000134)
SubClassOf(obo:CL_0020000 obo:CL_0000499)

# Class: obo:CL_0020001 (V1delta gamma-delta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25991474") Annotation(oboInOwl:hasDbXref "PMID:29680462") Annotation(oboInOwl:hasDbXref "PMID:35637401") Annotation(oboInOwl:hasDbXref "PMID:37989744") obo:IAO_0000115 obo:CL_0020001 "A mature gamma-delta T Cell with T cell receptors consisting of the Vδ1 segment paired with various V gamma chains. This cell is enriched in the gut, skin (Davey et al., 2018) and the female reproductive tract (Wu et al., 2022). It exhibits potent cytotoxic capabilities through perforin/granzyme and death receptor pathways.")
AnnotationAssertion(terms:contributor obo:CL_0020001 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_0020001 "2025-09-29T10:40:48Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020001 "Vδ1+ Gamma-Delta T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24895997") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020001 "Vδ1+ γδ T Cell")
AnnotationAssertion(rdfs:label obo:CL_0020001 "V1delta gamma-delta T cell")
SubClassOf(obo:CL_0020001 obo:CL_0000800)

# Class: obo:CL_0020002 (mucosal-associated invariant T cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26382249") Annotation(oboInOwl:hasDbXref "PMID:33352411") Annotation(oboInOwl:hasDbXref "PMID:35641678") Annotation(oboInOwl:hasDbXref "PMID:40781543") obo:IAO_0000115 obo:CL_0020002 "A mucosal-associated invariant T (MAIT) cell found in various tissues including human blood, liver, gut, and lung, characterised by a semi-invariant T cell receptor (TCR) comprising TRAV1-2 (Vα7.2) predominantly paired with TRAJ33, and high expression of CD161. Upon activation, MAIT cells produce inflammatory cytokines, including IFN-γ, TNF-α, and IL-17.")
AnnotationAssertion(terms:contributor obo:CL_0020002 <https://orcid.org/0000-0001-5742-4697>)
AnnotationAssertion(terms:contributor obo:CL_0020002 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_0020002 "2025-10-07T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0020002 "mucosal-associated invariant T lymphocyte, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0020002 "mucosal-associated invariant T-cell, human")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0020002 "mucosal-associated invariant T-lymphocyte, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:40781543") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020002 "MAIT, human")
AnnotationAssertion(rdfs:label obo:CL_0020002 "mucosal-associated invariant T cell, human")
EquivalentClasses(obo:CL_0020002 ObjectIntersectionOf(obo:CL_0000940 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_Q12918) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_A0A0B4J238) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_0020003 (internal globus pallidus core projecting neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11596046") Annotation(oboInOwl:hasDbXref "PMID:28384468") Annotation(oboInOwl:hasDbXref "PMID:28949036") Annotation(oboInOwl:hasDbXref "PMID:35927027") Annotation(oboInOwl:hasDbXref "PMID:7127069") obo:IAO_0000115 obo:CL_0020003 "A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001).")
AnnotationAssertion(terms:contributor obo:CL_0020003 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(terms:date obo:CL_0020003 "2025-01-31T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7127069") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020003 "GPi core")
AnnotationAssertion(rdfs:label obo:CL_0020003 "internal globus pallidus core projecting neuron")
AnnotationAssertion(Annotation(dc:license "https://creativecommons.org/licenses/by-nc-nd/4.0/") Annotation(oboInOwl:hasDbXref "PMID:35927027") foaf:depiction obo:CL_0020003 <http://purl.obolibrary.org/obo/cl/images/GPi_core_shell_myamoto.jpg>)
SubClassOf(obo:CL_0020003 obo:CL_0000617)
SubClassOf(obo:CL_0020003 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002477))
SubClassOf(obo:CL_0020003 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_0020003 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013502))

# Class: obo:CL_0020004 (internal globus pallidus shell projection neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11596046") Annotation(oboInOwl:hasDbXref "PMID:28384468") Annotation(oboInOwl:hasDbXref "PMID:30755721") Annotation(oboInOwl:hasDbXref "PMID:33787995") Annotation(oboInOwl:hasDbXref "PMID:7127069") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.03.16.484460") obo:IAO_0000115 obo:CL_0020004 "A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi.")
AnnotationAssertion(terms:contributor obo:CL_0020004 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020004 "2025-09-30T14:21:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28384468") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020004 "GPi shell")
AnnotationAssertion(rdfs:label obo:CL_0020004 "internal globus pallidus shell projection neuron")
SubClassOf(obo:CL_0020004 obo:CL_0000617)
SubClassOf(obo:CL_0020004 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002477))
SubClassOf(obo:CL_0020004 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015665))

# Class: obo:CL_0020005 (spiral ligament fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10675641") Annotation(oboInOwl:hasDbXref "PMID:33193034") obo:IAO_0000115 obo:CL_0020005 "An otic fibrocyte that is part of the spiral ligament. This cell is crucial in maintaining the endocochlear potential, regulating blood flow, participating in immune responses by secreting chemokines including MCP-1 and MIP-2, and producing extracellular matrix proteins such as collagen and cochlin.")
AnnotationAssertion(terms:contributor obo:CL_0020005 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020005 "2025-10-27T15:56:54Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33193034") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020005 "SLF")
AnnotationAssertion(rdfs:label obo:CL_0020005 "spiral ligament fibrocyte")
SubClassOf(obo:CL_0020005 obo:CL_0002665)
SubClassOf(obo:CL_0020005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006725))

# Class: obo:CL_0020006 (OB-Dopa-GABA)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35322231") obo:IAO_0000115 obo:CL_0020006 "A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum.")
AnnotationAssertion(terms:contributor obo:CL_0020006 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(rdfs:label obo:CL_0020006 "OB-Dopa-GABA")
SubClassOf(obo:CL_0020006 obo:CL_0000617)
SubClassOf(obo:CL_0020006 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_0020006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))
SubClassOf(obo:CL_0020006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0020007 (dorso-striatal cholinergic-GABAergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_0020007 "STRd Cholinergic GABA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10934256") Annotation(oboInOwl:hasDbXref "PMID:19855026") Annotation(oboInOwl:hasDbXref "PMID:29651049") Annotation(oboInOwl:hasDbXref "PMID:37464873") obo:IAO_0000115 obo:CL_0020007 "A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018).")
AnnotationAssertion(terms:contributor obo:CL_0020007 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(terms:date obo:CL_0020007 "2025-10-23T08:36:33Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0020007 "dorso-striatal cholinergic-GABAergic neuron")
SubClassOf(obo:CL_0020007 obo:CL_0000099)
SubClassOf(obo:CL_0020007 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_0020007 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055))
SubClassOf(obo:CL_0020007 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0020008 (striatal cholinergic-GABAergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_0020008 "STR Cholinergic GABA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10377365") Annotation(oboInOwl:hasDbXref "PMID:10934256") Annotation(oboInOwl:hasDbXref "PMID:21925242") Annotation(oboInOwl:hasDbXref "PMID:2329464") Annotation(oboInOwl:hasDbXref "PMID:25374536") Annotation(oboInOwl:hasDbXref "PMID:25876458") Annotation(oboInOwl:hasDbXref "PMID:29651049") Annotation(oboInOwl:hasDbXref "PMID:37905876") obo:IAO_0000115 obo:CL_0020008 "A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014).")
AnnotationAssertion(terms:contributor obo:CL_0020008 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10377365") Annotation(oboInOwl:hasDbXref "PMID:25876458") Annotation(oboInOwl:hasDbXref "PMID:29651049") Annotation(oboInOwl:hasDbXref "PMID:37905876") terms:description obo:CL_0020008 "Although they constitute only 1–3% of all striatal neurons, these interneurons form a major modulatory hub, integrating cortical, thalamic, and dopaminergic inputs and shaping striatal output dynamics (Gonzales & Smith, 2015; Wegman et al., 2024). Electrophysiologically, the neuron exhibits tonic autonomous firing at 3–10 Hz, broad action potentials, and a prominent hyperpolarization-activated inward current (Ih) (Bennett & Wilson, 1999; Goldberg & Reynolds, 2011). Functionally, it modulates corticostriatal and thalamostriatal synaptic transmission, dopamine release, and spiny projection neuron excitability through co-transmission of acetylcholine and GABA (Lozovaya et al., 2018; Wegman et al., 2024). This dual inhibitory and modulatory signaling underlies context-dependent control of synaptic plasticity, action selection, and reinforcement learning (Gonzales & Smith, 2015; Lozovaya et al., 2018).")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29651049") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020008 "CGIN")
AnnotationAssertion(rdfs:label obo:CL_0020008 "striatal cholinergic-GABAergic neuron")
SubClassOf(obo:CL_0020008 obo:CL_0000099)
SubClassOf(obo:CL_0020008 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_0020008 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055))
SubClassOf(obo:CL_0020008 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0020009 (prototypic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_0020009 "GPe SOX6-CTXND1 GABA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22726837") Annotation(oboInOwl:hasDbXref "PMID:25843402") Annotation(oboInOwl:hasDbXref "PMID:25926446") Annotation(oboInOwl:hasDbXref "PMID:27194328") Annotation(oboInOwl:hasDbXref "PMID:37336974") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.03.16.484460") obo:IAO_0000115 obo:CL_0020009 "A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015).")
AnnotationAssertion(terms:contributor obo:CL_0020009 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22726837") Annotation(oboInOwl:hasDbXref "PMID:25843402") Annotation(oboInOwl:hasDbXref "PMID:25926446") Annotation(oboInOwl:hasDbXref "PMID:37336974") terms:description obo:CL_0020009 "The prototypic neuron projects to downstream basal ganglia nuclei, including the subthalamic nucleus (STN), internal globus pallidus, and substantia nigra pars reticulata (SNr), with some neurons also emitting ascending collaterals that modestly innervate the striatum (Mallet et al., 2012, Abdi et al., 2015). It exhibits longer local axon collaterals with more boutons compared to arkypallidal neurons, supporting extensive local interconnectivity within the GPe (Mallet et al., 2012). The prototypic neuron plays a fundamental role in the indirect pathway of the basal ganglia, coordinating activity across basal ganglia nuclei through its widespread projections (Mallet et al., 2012, Courtney et al., 2023). Decreases in firing during movement are consistent with disinhibiting the STN and output nuclei, thereby facilitating the expression of desired motor patterns (Dodson et al., 2015, Courtney et al., 2023).")
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020009 "2025-10-17T09:12:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0020009 "prototypic neuron")
SubClassOf(obo:CL_0020009 obo:CL_0000617)
SubClassOf(obo:CL_0020009 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002476))
SubClassOf(obo:CL_0020009 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024))
SubClassOf(obo:CL_0020009 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000011241))

# Class: obo:CL_0020010 (arkypallidal neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_0020010 "GPe MEIS2-SOX6 GABA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22726837") Annotation(oboInOwl:hasDbXref "PMID:25843402") Annotation(oboInOwl:hasDbXref "PMID:25926446") Annotation(oboInOwl:hasDbXref "PMID:27194328") Annotation(oboInOwl:hasDbXref "PMID:37336974") obo:IAO_0000115 obo:CL_0020010 "A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012).")
AnnotationAssertion(terms:contributor obo:CL_0020010 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020010 "2025-10-16T10:21:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0020010 "arkypallidal neuron")
SubClassOf(obo:CL_0020010 obo:CL_0000617)
SubClassOf(obo:CL_0020010 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002476))
SubClassOf(obo:CL_0020010 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004025))
SubClassOf(obo:CL_0020010 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_0020011 (hair follicle associated fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20022473") Annotation(oboInOwl:hasDbXref "PMID:34297930") obo:IAO_0000115 obo:CL_0020011 "A specialized dermal fibroblast within the hair follicle mesenchymal compartment that participates in epithelial-mesenchymal signaling to regulate hair morphogenesis, cycling, and homeostasis through production of inductive signals and extracellular matrix maintenance.")
AnnotationAssertion(terms:contributor obo:CL_0020011 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_0020011 "2025-11-04T15:29:55Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_0020011 "hair follicle associated fibroblast")
EquivalentClasses(obo:CL_0020011 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0020011 obo:CL_0002620)

# Class: obo:CL_0020012 (hair follicle isthmus-associated fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:40993240") obo:IAO_0000115 obo:CL_0020012 "A fibroblast that is part of the hair follicle isthmus (mid-hair shaft). In humans, this cell expresses CRABP1/COCH/RSPO4 and tendon-associated genes (MKX, TNMD).")
AnnotationAssertion(terms:contributor obo:CL_0020012 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(rdfs:label obo:CL_0020012 "hair follicle isthmus-associated fibroblast")
EquivalentClasses(obo:CL_0020012 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006005)))

# Class: obo:CL_0020013 (dermal sheath fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31857493") Annotation(oboInOwl:hasDbXref "PMID:35069694") obo:IAO_0000115 obo:CL_0020013 "A fibroblast forming the connective tissue sheath that encloses the hair follicle epithelium from the level of the bulge downward to the hair bulb. This cell expresses characteristic markers, including DPEP1 in humans and COL11A1 and ACTA2 (alpha-smooth muscle actin) in mice and humans. Dermal sheath fibroblast possesses contractile properties mediated by calcium-calmodulin-myosin light chain kinase signalling, generating centripetal force during hair follicle catagen that relocates the dermal papilla to the stem cell niche.")
AnnotationAssertion(terms:contributor obo:CL_0020013 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34297930") oboInOwl:hasRelatedSynonym obo:CL_0020013 "DS fibroblast")
AnnotationAssertion(rdfs:label obo:CL_0020013 "dermal sheath fibroblast")
SubClassOf(obo:CL_0020013 obo:CL_0000057)
SubClassOf(obo:CL_0020013 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073))
SubClassOf(obo:CL_0020013 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006936))
SubClassOf(obo:CL_0020013 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003675))
SubClassOf(obo:CL_0020013 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000005694))
SubClassOf(obo:CL_0020013 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P16444))

# Class: obo:CL_0020014 (intrinsically photosensitive retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11834834") Annotation(oboInOwl:hasDbXref "PMID:20959623") Annotation(oboInOwl:hasDbXref "Wikipedia:Intrinsically_photosensitive_retinal_ganglion_cell") obo:IAO_0000115 obo:CL_0020014 "A retinal ganglion cell that is intrinsically photosensitive, functioning as a non-image-forming photoreceptor, distinguished from rod and cone photoreceptors by the expression of the photopigment melanopsin in mice and humans (Hattar et al., 2002; Tri Hoang Do & Yau, 2015). Located primarily in the ganglion cell layer with some displaced somata in the inner nuclear layer, this neuron depolarises directly in response to environmental irradiance (Tri Hoang Do & Yau, 2015). It projects via the retinohypothalamic tract to central targets, including the suprachiasmatic nucleus (SCN) for circadian photoentrainment and the olivary pretectal nucleus (OPN) for the pupillary light reflex.")
AnnotationAssertion(dc:creator obo:CL_0020014 "GitHub Copilot")
AnnotationAssertion(terms:contributor obo:CL_0020014 <https://orcid.org/0000-0003-2473-2313>)
AnnotationAssertion(terms:contributor obo:CL_0020014 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "http://www.wikidata.org/entity/Q934475") oboInOwl:hasBroadSynonym obo:CL_0020014 "photosensitive ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20959623") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020014 "ipRGC")
AnnotationAssertion(rdfs:label obo:CL_0020014 "intrinsically photosensitive retinal ganglion cell")
SubClassOf(obo:CL_0020014 obo:CL_0000210)
SubClassOf(obo:CL_0020014 obo:CL_0000740)
SubClassOf(obo:CL_0020014 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000966))
SubClassOf(obo:CL_0020014 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001243))

# Class: obo:CL_0020015 (transitional principal-intercalated cell of kidney collecting duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33893305") Annotation(oboInOwl:hasDbXref "PMID:37468583") obo:IAO_0000115 obo:CL_0020015 "A transitional cell located in the renal collecting duct that co-expresses markers of both principal cell (PC) and intercalated cell (IC). This hybrid cell is enriched in Chronic Kidney Disease (CKD).")
AnnotationAssertion(dc:creator obo:CL_0020015 "GitHub Copilot")
AnnotationAssertion(terms:contributor obo:CL_0020015 <https://orcid.org/0000-0002-2999-0103>)
AnnotationAssertion(terms:contributor obo:CL_0020015 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37468583") oboInOwl:hasBroadSynonym obo:CL_0020015 "hybrid principal-intercalated cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37468583") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020015 "tPC-IC cell")
AnnotationAssertion(rdfs:label obo:CL_0020015 "transitional principal-intercalated cell of kidney collecting duct")
SubClassOf(obo:CL_0020015 obo:CL_1000454)
SubClassOf(obo:CL_0020015 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232))

# Class: obo:CL_0020016 (osteochondral skeletal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34280086") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.12.07.570646") obo:IAO_0000115 obo:CL_0020016 "A tissue-specific stem cell with long-term self-renewal capacity that is restricted to generating bone, cartilage, and stromal cell lineages. This cell is primarily located in the growth plate (resting zone), periosteum, and subchondral bone regions, and is marked by high clonogenicity and robust multipotent differentiation potential in both osteogenic and chondrogenic lineages. Distinctively, ocSSC lacks adipogenic capacity, distinguishing it from other mesenchymal stem cell populations.")
AnnotationAssertion(terms:contributor obo:CL_0020016 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:creator obo:CL_0020016 "GitHub Copilot")
AnnotationAssertion(terms:date obo:CL_0020016 "2025-11-27T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34280086") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020016 "ocSSC")
AnnotationAssertion(rdfs:label obo:CL_0020016 "osteochondral skeletal stem cell")
SubClassOf(obo:CL_0020016 obo:CL_0000034)
SubClassOf(obo:CL_0020016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001434))
SubClassOf(obo:CL_0020016 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001649))
SubClassOf(obo:CL_0020016 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145))
SubClassOf(obo:CL_0020016 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0051216))

# Class: obo:CL_0020017 (M0 macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1186/s12885-022-09872-y") Annotation(oboInOwl:hasDbXref "PMID:30861466") obo:IAO_0000115 obo:CL_0020017 "A macrophage that has not yet undergone polarization into a specific macrophage subtype. These cells are non-activated and have the potential to differentiate into inflammatory (M1) or alternatively activated (M2) macrophage subtypes in response to appropriate stimuli.")
AnnotationAssertion(dc:creator obo:CL_0020017 "GitHub Copilot")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0020017 "naive macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0020017 "non-activated macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1186/s12885-022-09872-y") oboInOwl:hasExactSynonym obo:CL_0020017 "resting-state macrophages")
AnnotationAssertion(rdfs:label obo:CL_0020017 "M0 macrophage")
SubClassOf(obo:CL_0020017 obo:CL_0000235)

# Class: obo:CL_0020018 (proliferative fibrochondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasDbXref "PMID:39759119") obo:IAO_0000115 obo:CL_0020018 "A fibrochondrocyte located in fibrocartilage that exhibits active proliferation capacity and is in S phase of the cell cycle. It functions as a progenitor cell positioned at the root of developmental trajectories alongside fibrochondrocyte progenitors (FCP), with the capacity to diverge toward one of two developmental fates: (1) fibrochondrocytes and prehypertrophic chondrocytes, or (2) regulatory chondrocytes and prehypertrophic chondrocytes. It is characterised by co-expression of COL1A1, the growth factors FGF7 and CTGF, and the cell-cycle genes STMN1, KIAA0101, and MCM3 in humans. During early progenitor differentiation, FGF7 and COL1A1 expression increases and then declines as the cell commits to terminal fates.")
AnnotationAssertion(terms:contributor obo:CL_0020018 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:creator obo:CL_0020018 "GitHub Copilot")
AnnotationAssertion(terms:date obo:CL_0020018 "2025-11-27T12:48:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020018 "ProFC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") rdfs:comment obo:CL_0020018 "Lineage relationships are inferred from single-cell RNA-seq trajectories and validated through experimental approaches, including FACS isolation, functional differentiation assays, and in vivo developmental gene expression analysis.")
AnnotationAssertion(rdfs:label obo:CL_0020018 "proliferative fibrochondrocyte")
SubClassOf(obo:CL_0020018 obo:CL_4072104)
SubClassOf(obo:CL_0020018 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0022402))
SubClassOf(obo:CL_0020018 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003264))
SubClassOf(obo:CL_0020018 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007498))

# Class: obo:CL_0020019 (regulatory chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30026257") Annotation(oboInOwl:hasDbXref "PMID:34045450") Annotation(oboInOwl:hasDbXref "PMID:37660146") obo:IAO_0000115 obo:CL_0020019 "A chondrocyte located mainly in the superficial zone of articular cartilage. In healthy human cartilage, regulatory chondrocytes are characterized by expression of EIF5A, PGK1, ANXA1, and TUBA1A. During osteoarthritis, a distinct subpopulation expands, marked by high expression of CHI3L1, CHI3L2, CRTAC1, and AEBP1, with enrichment for signaling pathway regulation (including Toll-like receptor, mTOR, and TGF-beta signaling) and antigen-processing gene expression, with a small proportion expressing MHC class II genes, suggesting potential immune cell-like regulatory functions during osteoarthritis progression.")
AnnotationAssertion(dc:creator obo:CL_0020019 "GitHub Copilot")
AnnotationAssertion(terms:contributor obo:CL_0020019 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37660146") oboInOwl:hasRelatedSynonym obo:CL_0020019 "RegC")
AnnotationAssertion(rdfs:label obo:CL_0020019 "regulatory chondrocyte")
SubClassOf(obo:CL_0020019 obo:CL_0000138)

# Class: obo:CL_0020020 (homeostatic chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30026257") Annotation(oboInOwl:hasDbXref "PMID:34045450") Annotation(oboInOwl:hasDbXref "PMID:34400611") Annotation(oboInOwl:hasDbXref "PMID:37660146") obo:IAO_0000115 obo:CL_0020020 "A chondrocyte identified in both healthy and osteoarthritic human articular cartilage, and in intervertebral disc tissue. In healthy articular cartilage, a homeostatic chondrocyte is characterised by the expression of TXNIP, IFITM3, GDF15, and TIMP1 (Wang et al., 2021), among other extracellular matrix and regulatory molecules. This cell maintains cartilage integrity by producing key ECM components and supporting baseline tissue homeostasis. In OA cartilage, this cell is enriched for genes related to cellular homeostasis modulation, including regulation of the cell cycle, development, and RNA metabolism (Ji et al., 2018).")
AnnotationAssertion(dc:creator obo:CL_0020020 "GitHub Copilot")
AnnotationAssertion(terms:contributor obo:CL_0020020 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37660146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020020 "HomC")
AnnotationAssertion(rdfs:label obo:CL_0020020 "homeostatic chondrocyte")
SubClassOf(obo:CL_0020020 obo:CL_0000138)
SubClassOf(obo:CL_0020020 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))
SubClassOf(obo:CL_0020020 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_1990079))

# Class: obo:CL_0020021 (fibrochondrocyte progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasDbXref "PMID:36338137") obo:IAO_0000115 obo:CL_0020021 "A mesenchymal progenitor cell located in fibrocartilaginous tissues, along the fibrochondrocytic differentiation pathway that co-expresses both fibrochondrocyte markers (COL1A1, COL3A1) and mesenchymal stem cell markers (MCAM/CD146, MYLK) in humans. This cell serves as a progenitor for mature fibrochondrocytes and other meniscal cell types, with differentiation regulated by TGF-β signaling, focal adhesion, and extracellular matrix-receptor interaction pathways.")
AnnotationAssertion(terms:contributor obo:CL_0020021 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:creator obo:CL_0020021 "GitHub Copilot")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020021 "FCP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") rdfs:comment obo:CL_0020021 "A fibrochondrocyte progenitor cell demonstrates colony-forming capacity and multi-lineage differentiation potential toward osteogenic and adipogenic lineages.")
AnnotationAssertion(rdfs:label obo:CL_0020021 "fibrochondrocyte progenitor cell")
SubClassOf(obo:CL_0020021 obo:CL_0008019)
SubClassOf(obo:CL_0020021 obo:CL_0011026)
SubClassOf(obo:CL_0020021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001995))

# Class: obo:CL_0020022 (prehypertrophic chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29985449") Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasDbXref "PMID:34137454") obo:IAO_0000115 obo:CL_0020022 "A post-proliferative chondrocyte in the prehypertrophic zone of the cartilage tissue, located between the proliferative and hypertrophic zones. This cell is characterised by increased cell volume and expression of Indian Hedgehog (Ihh), PTH1R, and Runx2/3 in both humans and mice (Hallett et al., 2021). It coordinates the PTHrP-Ihh feedback loop that regulates chondrocyte differentiation and functions as a signalling hub for communication between proliferative chondrocytes, hypertrophic chondrocytes, and periosteal osteoblasts (Hallett et al., 2021).")
AnnotationAssertion(terms:contributor obo:CL_0020022 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020022 "preHTC")
AnnotationAssertion(rdfs:label obo:CL_0020022 "prehypertrophic chondrocyte")
SubClassOf(obo:CL_0020022 obo:CL_0000138)
SubClassOf(obo:CL_0020022 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_0000743))

# Class: obo:CL_0020023 (effector chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21652695") Annotation(oboInOwl:hasDbXref "PMID:30026257") Annotation(oboInOwl:hasDbXref "PMID:34400611") Annotation(oboInOwl:hasDbXref "PMID:38868774") Annotation(oboInOwl:hasDbXref "PMID:40753276") obo:IAO_0000115 obo:CL_0020023 "A metabolically highly active chondrocyte that is identified in the cartilaginous tissues, including articular cartilage and intervertebral disc cartilage. In the human articular cartilage, this cell is marked by genes such as CYTL1, FRZB, CLEC3A, and S100B (Ji et al., 2018; Raut et al.,2025). This cell demonstrates strong metabolic activity and is implicated in extracellular matrix regulation and adaptive responses (Ji et al., 2018; Gan et al., 2021; Raut et al.,2025).")
AnnotationAssertion(terms:contributor obo:CL_0020023 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:creator obo:CL_0020023 "GitHub Copilot")
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020023 "2025-12-01T11:46:23Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38868774") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020023 "EC")
AnnotationAssertion(rdfs:label obo:CL_0020023 "effector chondrocyte")
SubClassOf(obo:CL_0020023 obo:CL_0000138)

# Class: obo:CL_0020024 (alpha retinal ganglion cell OFF-sustained (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasDbXref "PMID:35830791") Annotation(oboInOwl:hasDbXref "PMID:37066415") obo:IAO_0000115 obo:CL_0020024 "A mouse retinal ganglion cell type defined by a large soma and a wide, monostratified dendritic arbor that stratifies just distal to the outer ChAT band of the inner plexiform layer (Krieger et al., 2017). It corresponds to the G5 physiological type (Baden et al., 2016; Goetz et al., 2022) and the C42 transcriptomic cluster (Tran et al., 2019), and is considered the evolutionary ortholog of the primate OFF midget RGC (Hahn et al., 2023). The cell projects a thick, fast-conducting axon to the dorsal lateral geniculate nucleus and superior colliculus. It shows a sustained increase in firing to light decrements with a slow decay time constant of roughly 250 ms and a large receptive field center with weak surround antagonism (Krieger et al., 2017). Its molecular profile includes expression of Spp1 and Neurofilament (Smi32) together with Brn3a (Pou4f1) and Brn3b (Pou4f2), absence of Brn3c (Pou4f3) and Calbindin (Calb1), and strong enrichment of Fes (Krieger et al., 2017; Tran et al., 2019).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0020024 obo:NCBITaxon_10090)
AnnotationAssertion(terms:contributor obo:CL_0020024 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(terms:creator obo:CL_0020024 "GitHub Copilot")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31784286") oboInOwl:hasExactSynonym obo:CL_0020024 "C42")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") oboInOwl:hasExactSynonym obo:CL_0020024 "G5")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020024 "alpha retinal ganglion cell OFF-s")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") rdfs:comment obo:CL_0020024 "The G-type nomenclature used here refers specifically to the functional classification of mouse retinal ganglion cells introduced by Baden and colleagues, and is distinct from earlier G-based schemes used for rabbit or other species. Readers should be aware that the same letter–number labels (e.g., \"G1\", \"G2\") have been applied in different historical contexts to different animals and criteria (functional vs. morphological), so cross-species or cross-era comparisons of \"G\" names should not be assumed equivalent without explicit mapping in the primary literature.")
AnnotationAssertion(rdfs:label obo:CL_0020024 "alpha retinal ganglion cell OFF-sustained (Mmus)")
SubClassOf(obo:CL_0020024 obo:CL_0004117)
SubClassOf(obo:CL_0020024 obo:CL_4023033)
SubClassOf(obo:CL_0020024 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0020025 (alpha retinal ganglion cell ON-sustained (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasDbXref "PMID:31784286") Annotation(oboInOwl:hasDbXref "PMID:35830791") Annotation(oboInOwl:hasDbXref "PMID:38092908") obo:IAO_0000115 obo:CL_0020025 "A retinal ganglion cell type that has a large soma and a wide, monostratified dendritic arbor that stratifies in the inner sublamina of the inner plexiform layer, with dendrites located just proximal to the inner ChAT band (Krieger et al., 2017). It shows a sustained increase in firing rate to ON stimuli (Krieger et al., 2017). It corresponds to the G24 functional type (Baden et al., 2016; Goetz et al., 2022), the C43 transcriptomic cluster (Tran et al., 2019), and is considered the mouse ortholog of the primate ON midget retinal ganglion cell (Hahn et al., 2023). It is molecularly defined by expression of Spp1, Smi32, Brn3b, Calbindin, and Tbr2 (Krieger et al., 2017; Tran et al., 2019).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0020025 obo:NCBITaxon_10090)
AnnotationAssertion(terms:contributor obo:CL_0020025 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:creator obo:CL_0020025 "GitHub Copilot")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31784286") oboInOwl:hasExactSynonym obo:CL_0020025 "C43")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:35830791") oboInOwl:hasExactSynonym obo:CL_0020025 "G24")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020025 "alpha retinal ganglion cell ON-s")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") rdfs:comment obo:CL_0020025 "The G-type nomenclature used here refers specifically to the functional classification of mouse retinal ganglion cells introduced by Baden and colleagues, and is distinct from earlier G-based schemes used for rabbit or other species. Readers should be aware that the same letter–number labels (e.g., \"G1\", \"G2\") have been applied in different historical contexts to different animals and criteria (functional vs. morphological), so cross-species or cross-era comparisons of \"G\" names should not be assumed equivalent without explicit mapping in the primary literature.")
AnnotationAssertion(rdfs:label obo:CL_0020025 "alpha retinal ganglion cell ON-sustained (Mmus)")
SubClassOf(obo:CL_0020025 obo:CL_0004117)
SubClassOf(obo:CL_0020025 obo:CL_4023032)
SubClassOf(obo:CL_0020025 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0020026 (alpha retinal ganglion cell OFF-transient (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasDbXref "PMID:35830791") Annotation(oboInOwl:hasDbXref "PMID:37066415") obo:IAO_0000115 obo:CL_0020026 "An alpha retinal ganglion cell subtype found in the mouse retina that responds selectively and transiently to decreases in light intensity. It is characterized by a large soma, a broad dendritic arbor that stratifies within sublamina a of the inner plexiform layer, and rapid OFF-transient firing kinetics that decay even during sustained stimulation (Krieger et al., 2017). Functionally, it corresponds to G8 in the Baden functional classification (Baden et al., 2016; Goetz et al., 2022) and C45 in the Tran transcriptomic atlas (Tran et al., 2019), and it is considered the evolutionary ortholog of the primate OFF Parasol RGC (Hahn et al., 2023). This cell type acts as a detector of rapidly approaching dark objects and contributes to innate defensive responses by encoding looming stimuli (Münch et al., 2009). It exhibits a distinctive molecular signature by its expression of Brn3c (Krieger et al., 2017).")
AnnotationAssertion(obo:IAO_0000233 obo:CL_0020026 "https://github.com/obophenotype/cell-ontology/issues/3493")
AnnotationAssertion(terms:contributor obo:CL_0020026 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(terms:creator obo:CL_0020026 "GitHub Copilot")
AnnotationAssertion(oboInOwl:creation_date obo:CL_0020026 "2025-12-05T11:29:19Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0020026 "alpha retinal ganglion cell OFF-t")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") rdfs:comment obo:CL_0020026 "The G-type nomenclature used here refers specifically to the functional classification of mouse retinal ganglion cells introduced by Baden and colleagues, and is distinct from earlier G-based schemes used for rabbit or other species. Readers should be aware that the same letter–number labels (e.g., \"G1\", \"G2\") have been applied in different historical contexts to different animals and criteria (functional vs. morphological), so cross-species or cross-era comparisons of \"G\" names should not be assumed equivalent without explicit mapping in the primary literature.")
AnnotationAssertion(rdfs:label obo:CL_0020026 "alpha retinal ganglion cell OFF-transient (Mmus)")
SubClassOf(obo:CL_0020026 obo:CL_0004117)
SubClassOf(obo:CL_0020026 obo:CL_4023033)
SubClassOf(obo:CL_0020026 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0020027 (alpha retinal ganglion cell ON-transient (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:28753612") Annotation(oboInOwl:hasDbXref "PMID:31784286") Annotation(oboInOwl:hasDbXref "PMID:35830791") Annotation(oboInOwl:hasDbXref "PMID:37066415") obo:IAO_0000115 obo:CL_0020027 "An alpha retinal ganglion cell subtype in the mouse retina that responds selectively and transiently to increases in light intensity. It possesses the large soma and expansive dendritic field characteristic of alpha RGCs (Krieger et al., 2017). This cell exhibits a brief, fast-decaying burst of firing at the onset of light increments and contributes to motion detection for luminance increases, forming the ON-branch of the transient magnocellular-like pathway (Krieger et al., 2017; Hahn et al., 2023). Functionally, it corresponds to cluster G19 and aligns transcriptomically with cluster C41 (Krieger et al., 2017; Tran et al., 2019). It is orthologous to the primate ON Parasol RGC (Hahn et al., 2023). Molecularly, it expresses Spp1, Smi32, and Brn3b, but lacks Brn3a, Brn3c, and Calbindin (Krieger et al., 2017).")
AnnotationAssertion(obo:RO_0002175 obo:CL_0020027 obo:NCBITaxon_10090)
AnnotationAssertion(terms:contributor obo:CL_0020027 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(terms:creator obo:CL_0020027 "GitHub Copilot")
AnnotationAssertion(terms:date obo:CL_0020027 "2025-12-05T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31784286") oboInOwl:hasExactSynonym obo:CL_0020027 "C41")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") Annotation(oboInOwl:hasDbXref "PMID:28753612") oboInOwl:hasExactSynonym obo:CL_0020027 "G19")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28753612") oboInOwl:hasRelatedSynonym obo:CL_0020027 "alpha retinal ganglion cell ON-t")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26735013") rdfs:comment obo:CL_0020027 "The G-type nomenclature used here refers specifically to the functional classification of mouse retinal ganglion cells introduced by Baden and colleagues, and is distinct from earlier G-based schemes used for rabbit or other species. Readers should be aware that the same letter–number labels (e.g., \"G1\", \"G2\") have been applied in different historical contexts to different animals and criteria (functional vs. morphological), so cross-species or cross-era comparisons of \"G\" names should not be assumed equivalent without explicit mapping in the primary literature.")
AnnotationAssertion(rdfs:label obo:CL_0020027 "alpha retinal ganglion cell ON-transient (Mmus)")
SubClassOf(obo:CL_0020027 obo:CL_0004117)
SubClassOf(obo:CL_0020027 obo:CL_4023032)
SubClassOf(obo:CL_0020027 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_0700009 (obsolete kidney collecting duct beta-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24051376") Annotation(oboInOwl:hasDbXref "PMID:31300091") Annotation(oboInOwl:hasDbXref "PMID:32016094") obo:IAO_0000115 obo:CL_0700009 "OBSOLETE. A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_0700009 obo:CL_4030005)
AnnotationAssertion(terms:date obo:CL_0700009 "2022-08-26T10:31:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32016094") oboInOwl:hasExactSynonym obo:CL_0700009 "B-IC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31300091") oboInOwl:hasExactSynonym obo:CL_0700009 "kidney collecting duct intercalated cell type B")
AnnotationAssertion(rdfs:comment obo:CL_0700009 "Created with IRI in incorrect ID range")
AnnotationAssertion(rdfs:label obo:CL_0700009 "obsolete kidney collecting duct beta-intercalated cell")
AnnotationAssertion(owl:deprecated obo:CL_0700009 "true"^^xsd:boolean)

# Class: obo:CL_1000001 (retrotrapezoid nucleus neuron)

AnnotationAssertion(rdfs:label obo:CL_1000001 "retrotrapezoid nucleus neuron")
EquivalentClasses(obo:CL_1000001 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0009918)))

# Class: obo:CL_1000022 (mesonephric nephron tubule epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_1000022 "mesonephric nephron tubule epithelial cell")
EquivalentClasses(obo:CL_1000022 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005329)))

# Class: obo:CL_1000036 (obo:CL_1000036)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000036 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000036 obo:CL_0002196)
AnnotationAssertion(owl:deprecated obo:CL_1000036 "true"^^xsd:boolean)

# Class: obo:CL_1000042 (forebrain neuroblast)

AnnotationAssertion(rdfs:label obo:CL_1000042 "forebrain neuroblast")
EquivalentClasses(obo:CL_1000042 ObjectIntersectionOf(obo:CL_0000031 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001890)))

# Class: obo:CL_1000050 (lateral line nerve glial cell)

AnnotationAssertion(rdfs:label obo:CL_1000050 "lateral line nerve glial cell")
EquivalentClasses(obo:CL_1000050 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008906)))

# Class: obo:CL_1000073 (spinal cord radial glial cell)

AnnotationAssertion(rdfs:label obo:CL_1000073 "spinal cord radial glial cell")
EquivalentClasses(obo:CL_1000073 ObjectIntersectionOf(obo:CL_0000681 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002240)))

# Class: obo:CL_1000082 (stretch receptor cell)

AnnotationAssertion(rdfs:label obo:CL_1000082 "stretch receptor cell")
SubClassOf(obo:CL_1000082 obo:CL_0000006)

# Class: obo:CL_1000083 (stratified keratinized epithelial stem cell)

AnnotationAssertion(rdfs:label obo:CL_1000083 "stratified keratinized epithelial stem cell")
SubClassOf(obo:CL_1000083 obo:CL_0000357)

# Class: obo:CL_1000085 (stratified non keratinized epithelial stem cell)

AnnotationAssertion(rdfs:label obo:CL_1000085 "stratified non keratinized epithelial stem cell")
SubClassOf(obo:CL_1000085 obo:CL_0000357)

# Class: obo:CL_1000090 (pronephric nephron tubule epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_1000090 "pronephric nephron tubule epithelial cell")
EquivalentClasses(obo:CL_1000090 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005310)))

# Class: obo:CL_1000123 (metanephric nephron tubule epithelial cell)

AnnotationAssertion(rdfs:label obo:CL_1000123 "metanephric nephron tubule epithelial cell")
EquivalentClasses(obo:CL_1000123 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005146)))

# Class: obo:CL_1000143 (lung goblet cell)

AnnotationAssertion(rdfs:label obo:CL_1000143 "lung goblet cell")
EquivalentClasses(obo:CL_1000143 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000115)))

# Class: obo:CL_1000147 (cardiac valve cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") obo:IAO_0000115 obo:CL_1000147 "A cell that is part of a cardiac valve.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30796046") oboInOwl:hasExactSynonym obo:CL_1000147 "heart valve cell")
AnnotationAssertion(rdfs:label obo:CL_1000147 "cardiac valve cell")
EquivalentClasses(obo:CL_1000147 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000946)))

# Class: obo:CL_1000155 (Malpighian tubule stellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0061330") obo:IAO_0000115 obo:CL_1000155 "A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FBbt:00005797") oboInOwl:hasExactSynonym obo:CL_1000155 "Malpighian tubule Type II cell")
AnnotationAssertion(rdfs:label obo:CL_1000155 "Malpighian tubule stellate cell")
SubClassOf(obo:CL_1000155 obo:CL_0000151)
SubClassOf(obo:CL_1000155 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001054))

# Class: obo:CL_1000182 (malpighian tubule tip cell)

AnnotationAssertion(rdfs:label obo:CL_1000182 "malpighian tubule tip cell")
EquivalentClasses(obo:CL_1000182 ObjectIntersectionOf(obo:CL_0000423 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001054)))

# Class: obo:CL_1000191 (pillar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:12417662") obo:IAO_0000115 obo:CL_1000191 "A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000191 "FMA:75722")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000191 "pillar cell of cochlea")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000191 "pillar cell of corti")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000191 "rod cell of Corti")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1000191 "cochlear pillar cell")
AnnotationAssertion(rdfs:label obo:CL_1000191 "pillar cell")
SubClassOf(obo:CL_1000191 obo:CL_0002490)

# Class: obo:CL_1000217 (growth plate cartilage chondrocyte)

AnnotationAssertion(rdfs:label obo:CL_1000217 "growth plate cartilage chondrocyte")
EquivalentClasses(obo:CL_1000217 ObjectIntersectionOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004129)))

# Class: obo:CL_1000222 (stomach neuroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15153415") obo:IAO_0000115 obo:CL_1000222 "A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15153415") oboInOwl:hasBroadSynonym obo:CL_1000222 "DES cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15153415") oboInOwl:hasBroadSynonym obo:CL_1000222 "diffuse endocrine system cell")
AnnotationAssertion(rdfs:label obo:CL_1000222 "stomach neuroendocrine cell")
EquivalentClasses(obo:CL_1000222 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))
SubClassOf(obo:CL_1000222 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046717))

# Class: obo:CL_1000223 (pulmonary neuroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") Annotation(oboInOwl:hasDbXref "doi:10.3109/01902148209069653") Annotation(oboInOwl:hasDbXref "doi:10.7554/eLife.78216") obo:IAO_0000115 obo:CL_1000223 "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15018448") oboInOwl:hasExactSynonym obo:CL_1000223 "lung neuroendocrine cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_1000223 "PNEC")
AnnotationAssertion(rdfs:label obo:CL_1000223 "pulmonary neuroendocrine cell")
EquivalentClasses(obo:CL_1000223 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
SubClassOf(obo:CL_1000223 obo:CL_0000206)
SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031045))
SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820))
SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070483))

# Class: obo:CL_1000236 (posterior lateral line nerve glial cell)

AnnotationAssertion(rdfs:label obo:CL_1000236 "posterior lateral line nerve glial cell")
EquivalentClasses(obo:CL_1000236 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_2000175)))

# Class: obo:CL_1000239 (anterior lateral line nerve glial cell)

AnnotationAssertion(rdfs:label obo:CL_1000239 "anterior lateral line nerve glial cell")
EquivalentClasses(obo:CL_1000239 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_2000425)))

# Class: obo:CL_1000245 (posterior lateral line ganglion neuron)

AnnotationAssertion(rdfs:label obo:CL_1000245 "posterior lateral line ganglion neuron")
EquivalentClasses(obo:CL_1000245 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_2001314)))

# Class: obo:CL_1000271 (lung multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27864314") obo:IAO_0000115 obo:CL_1000271 "An epithelial cell that is part of the lung epithelium. This cell is characterised by the presence of cilia on its apical surface.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000271 "lung ciliated cell")
AnnotationAssertion(rdfs:label obo:CL_1000271 "lung multiciliated epithelial cell")
EquivalentClasses(obo:CL_1000271 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000115) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_1000272 (lung secretory cell)

AnnotationAssertion(rdfs:label obo:CL_1000272 "lung secretory cell")
EquivalentClasses(obo:CL_1000272 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))

# Class: obo:CL_1000274 (trophectodermal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22918806") obo:IAO_0000115 obo:CL_1000274 "An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000274 "trophectoderm cell")
AnnotationAssertion(rdfs:label obo:CL_1000274 "trophectodermal cell")
EquivalentClasses(obo:CL_1000274 ObjectIntersectionOf(obo:CL_0000349 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004345)))
SubClassOf(obo:CL_1000274 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000351))

# Class: obo:CL_1000275 (smooth muscle cell of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000275 "A smooth muscle cell that is part of the small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000275 "FMA:15050")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15050") oboInOwl:hasExactSynonym obo:CL_1000275 "non-striated muscle fiber of small intestine")
AnnotationAssertion(rdfs:label obo:CL_1000275 "smooth muscle cell of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_1000275 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_1000275 ObjectIntersectionOf(obo:CL_0002504 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000275 obo:CL_0002504)

# Class: obo:CL_1000276 (smooth muscle fiber of duodenum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000276 "A smooth muscle cell that is part of the duodenum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000276 "FMA:15058")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15058") oboInOwl:hasExactSynonym obo:CL_1000276 "non-striated muscle fiber of duodenum")
AnnotationAssertion(rdfs:label obo:CL_1000276 "smooth muscle fiber of duodenum")
EquivalentClasses(obo:CL_1000276 ObjectIntersectionOf(obo:CL_1000275 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000276 obo:CL_1000275)
SubClassOf(obo:CL_1000276 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000277 (smooth muscle fiber of jejunum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000277 "A smooth muscle cell that is part of the jejunum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000277 "FMA:15062")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15062") oboInOwl:hasExactSynonym obo:CL_1000277 "non-striated muscle fiber of jejunum")
AnnotationAssertion(rdfs:label obo:CL_1000277 "smooth muscle fiber of jejunum")
EquivalentClasses(obo:CL_1000277 ObjectIntersectionOf(obo:CL_1000275 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002115)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000277 obo:CL_1000275)

# Class: obo:CL_1000278 (smooth muscle fiber of ileum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000278 "A smooth muscle cell that is part of the ileum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000278 "FMA:15066")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15066") oboInOwl:hasExactSynonym obo:CL_1000278 "non-striated muscle fiber of ileum")
AnnotationAssertion(rdfs:label obo:CL_1000278 "smooth muscle fiber of ileum")
EquivalentClasses(obo:CL_1000278 ObjectIntersectionOf(obo:CL_1000275 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002116)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000278 obo:CL_1000275)
SubClassOf(obo:CL_1000278 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000279 (smooth muscle cell of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000279 "A smooth muscle cell that is part of the large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000279 "FMA:15653")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15653") oboInOwl:hasExactSynonym obo:CL_1000279 "non-striated muscle fiber of large intestine")
AnnotationAssertion(rdfs:label obo:CL_1000279 "smooth muscle cell of large intestine")
EquivalentClasses(obo:CL_1000279 ObjectIntersectionOf(obo:CL_0002504 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000059)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000279 obo:CL_0002504)

# Class: obo:CL_1000280 (smooth muscle cell of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000280 "A smooth muscle cell that is part of the colon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000280 "FMA:15663")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15663") oboInOwl:hasExactSynonym obo:CL_1000280 "non-striated muscle fiber of colon")
AnnotationAssertion(rdfs:label obo:CL_1000280 "smooth muscle cell of colon")
EquivalentClasses(obo:CL_1000280 ObjectIntersectionOf(obo:CL_0002504 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000280 obo:CL_0002504)
SubClassOf(obo:CL_1000280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_1000281 (smooth muscle cell of cecum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000281 "A smooth muscle cell that is part of the cecum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000281 "FMA:15681")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:15681") oboInOwl:hasExactSynonym obo:CL_1000281 "non-striated muscle fiber of cecum")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000281 "smooth muscle fiber of cecum")
AnnotationAssertion(rdfs:label obo:CL_1000281 "smooth muscle cell of cecum")
EquivalentClasses(obo:CL_1000281 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001153)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000281 obo:CL_0000192)
SubClassOf(obo:CL_1000281 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_1000282 (smooth muscle fiber of ascending colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000282 "A smooth muscle cell that is part of the ascending colon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000282 "FMA:17518")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:17518") oboInOwl:hasExactSynonym obo:CL_1000282 "non-striated muscle fiber of ascending colon")
AnnotationAssertion(rdfs:label obo:CL_1000282 "smooth muscle fiber of ascending colon")
EquivalentClasses(obo:CL_1000282 ObjectIntersectionOf(obo:CL_1000280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001156)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000282 obo:CL_1000280)

# Class: obo:CL_1000283 (smooth muscle fiber of transverse colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000283 "A smooth muscle cell that is part of the transverse colon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000283 "FMA:17519")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:17519") oboInOwl:hasExactSynonym obo:CL_1000283 "non-striated muscle fiber of transverse colon")
AnnotationAssertion(rdfs:label obo:CL_1000283 "smooth muscle fiber of transverse colon")
EquivalentClasses(obo:CL_1000283 ObjectIntersectionOf(obo:CL_1000280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001157)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000283 obo:CL_1000280)

# Class: obo:CL_1000284 (smooth muscle fiber of descending colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000284 "A smooth muscle cell that is part of the descending colon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000284 "FMA:17520")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:17520") oboInOwl:hasExactSynonym obo:CL_1000284 "non-striated muscle fiber of descending colon")
AnnotationAssertion(rdfs:label obo:CL_1000284 "smooth muscle fiber of descending colon")
EquivalentClasses(obo:CL_1000284 ObjectIntersectionOf(obo:CL_1000280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001158)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000284 obo:CL_1000280)

# Class: obo:CL_1000285 (smooth muscle cell of sigmoid colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000285 "A smooth muscle cell that is part of the sigmoid colon.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000285 "FMA:17521")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:17521") oboInOwl:hasExactSynonym obo:CL_1000285 "non-striated muscle fiber of sigmoid colon")
AnnotationAssertion(rdfs:label obo:CL_1000285 "smooth muscle cell of sigmoid colon")
EquivalentClasses(obo:CL_1000285 ObjectIntersectionOf(obo:CL_1000280 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001159)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000285 obo:CL_1000280)

# Class: obo:CL_1000286 (smooth muscle cell of rectum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000286 "A smooth muscle cell that is part of the rectum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000286 "FMA:17522")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:17522") oboInOwl:hasExactSynonym obo:CL_1000286 "non-striated muscle fiber of rectum")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000286 "smooth muscle fiber of rectum")
AnnotationAssertion(rdfs:label obo:CL_1000286 "smooth muscle cell of rectum")
EquivalentClasses(obo:CL_1000286 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001052)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000286 obo:CL_0002504)
SubClassOf(obo:CL_1000286 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_1000287 (myocyte of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000287 "A muscle cell that is part of the anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000287 "FMA:223276")
AnnotationAssertion(rdfs:label obo:CL_1000287 "myocyte of anterior internodal tract")
SubClassOf(obo:CL_1000287 obo:CL_0002096)

# Class: obo:CL_1000288 (myocyte of atrial branch of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000288 "A muscle cell that is part of the atrial branch of anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000288 "FMA:223277")
AnnotationAssertion(rdfs:label obo:CL_1000288 "myocyte of atrial branch of anterior internodal tract")
SubClassOf(obo:CL_1000288 obo:CL_0002096)

# Class: obo:CL_1000289 (myocyte of atrial septal branch of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000289 "A muscle cell that is part of the atrial septal branch of anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000289 "FMA:223278")
AnnotationAssertion(rdfs:label obo:CL_1000289 "myocyte of atrial septal branch of anterior internodal tract")
SubClassOf(obo:CL_1000289 obo:CL_0002096)

# Class: obo:CL_1000290 (myocyte of middle internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000290 "A muscle cell that is part of the middle internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000290 "FMA:223279")
AnnotationAssertion(rdfs:label obo:CL_1000290 "myocyte of middle internodal tract")
SubClassOf(obo:CL_1000290 obo:CL_0002096)

# Class: obo:CL_1000291 (myocyte of posterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000291 "A muscle cell that is part of the posterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000291 "FMA:223280")
AnnotationAssertion(rdfs:label obo:CL_1000291 "myocyte of posterior internodal tract")
SubClassOf(obo:CL_1000291 obo:CL_0002096)

# Class: obo:CL_1000292 (obo:CL_1000292)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000292 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000292 obo:CL_0002253)
AnnotationAssertion(owl:deprecated obo:CL_1000292 "true"^^xsd:boolean)

# Class: obo:CL_1000293 (obo:CL_1000293)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000293 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000293 obo:CL_0002254)
AnnotationAssertion(owl:deprecated obo:CL_1000293 "true"^^xsd:boolean)

# Class: obo:CL_1000294 (obo:CL_1000294)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000294 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000294 obo:CL_0002149)
AnnotationAssertion(owl:deprecated obo:CL_1000294 "true"^^xsd:boolean)

# Class: obo:CL_1000295 (obo:CL_1000295)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000295 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000295 obo:CL_0002231)
AnnotationAssertion(owl:deprecated obo:CL_1000295 "true"^^xsd:boolean)

# Class: obo:CL_1000296 (epithelial cell of urethra)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000296 "An epithelial cell that is part of the urethra.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000296 "FMA:256165")
AnnotationAssertion(rdfs:label obo:CL_1000296 "epithelial cell of urethra")
EquivalentClasses(obo:CL_1000296 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000057)))

# Class: obo:CL_1000297 (obo:CL_1000297)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000297 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000297 obo:CL_0002257)
AnnotationAssertion(owl:deprecated obo:CL_1000297 "true"^^xsd:boolean)

# Class: obo:CL_1000298 (mesothelial cell of dura mater)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000298 "A mesothelial cell that is part of the dura mater.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000298 "FMA:256516")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:256516") oboInOwl:hasExactSynonym obo:CL_1000298 "squamous mesothelial cell of dura mater")
AnnotationAssertion(rdfs:label obo:CL_1000298 "mesothelial cell of dura mater")
EquivalentClasses(obo:CL_1000298 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002363)))

# Class: obo:CL_1000299 (fibroblast of connective tissue of prostate)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000299 "A fibroblast that is part of the connective tissue of prostate.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000299 "FMA:261271")
AnnotationAssertion(rdfs:label obo:CL_1000299 "fibroblast of connective tissue of prostate")
SubClassOf(obo:CL_1000299 obo:CL_0000057)
SubClassOf(obo:CL_1000299 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367))

# Class: obo:CL_1000300 (fibroblast of outer membrane of prostatic capsule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000300 "A fibroblast that is part of the outer membrane of prostatic capsule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000300 "FMA:261273")
AnnotationAssertion(rdfs:label obo:CL_1000300 "fibroblast of outer membrane of prostatic capsule")
SubClassOf(obo:CL_1000300 obo:CL_0000057)
SubClassOf(obo:CL_1000300 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367))

# Class: obo:CL_1000301 (fibroblast of subepithelial connective tissue of prostatic gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000301 "A fibroblast that is part of the subepithelial connective tissue of prostatic gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000301 "FMA:261275")
AnnotationAssertion(rdfs:label obo:CL_1000301 "fibroblast of subepithelial connective tissue of prostatic gland")
SubClassOf(obo:CL_1000301 obo:CL_0000057)
SubClassOf(obo:CL_1000301 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367))

# Class: obo:CL_1000302 (fibroblast of papillary layer of dermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000302 "A fibroblast that is part of the papillary layer of dermis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000302 "FMA:261277")
AnnotationAssertion(rdfs:label obo:CL_1000302 "fibroblast of papillary layer of dermis")
EquivalentClasses(obo:CL_1000302 ObjectIntersectionOf(obo:CL_0002551 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001992)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000302 obo:CL_0002551)

# Class: obo:CL_1000303 (fibroblast of areolar connective tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000303 "A fibroblast that is part of the areolar connective tissue.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000303 "FMA:261279")
AnnotationAssertion(rdfs:label obo:CL_1000303 "fibroblast of areolar connective tissue")
EquivalentClasses(obo:CL_1000303 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006815)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000303 obo:CL_0000057)
SubClassOf(obo:CL_1000303 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006815))

# Class: obo:CL_1000304 (fibroblast of connective tissue of nonglandular part of prostate)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000304 "A fibroblast that is part of the connective tissue of nonglandular part of prostate.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000304 "FMA:261281")
AnnotationAssertion(rdfs:label obo:CL_1000304 "fibroblast of connective tissue of nonglandular part of prostate")
SubClassOf(obo:CL_1000304 obo:CL_0000057)
SubClassOf(obo:CL_1000304 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367))

# Class: obo:CL_1000305 (fibroblast of connective tissue of glandular part of prostate)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000305 "A fibroblast that is part of the connective tissue of glandular part of prostate.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000305 "FMA:261283")
AnnotationAssertion(rdfs:label obo:CL_1000305 "fibroblast of connective tissue of glandular part of prostate")
SubClassOf(obo:CL_1000305 obo:CL_0000057)
SubClassOf(obo:CL_1000305 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367))

# Class: obo:CL_1000306 (fibroblast of tunica adventitia of artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000306 "A fibroblast that is part of the tunica adventitia of artery.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000306 "FMA:261285")
AnnotationAssertion(rdfs:label obo:CL_1000306 "fibroblast of tunica adventitia of artery")
EquivalentClasses(obo:CL_1000306 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007240)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000306 obo:CL_0000057)

# Class: obo:CL_1000307 (fibroblast of dense regular elastic tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000307 "A fibroblast that is part of the dense regular elastic tissue.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000307 "FMA:261287")
AnnotationAssertion(rdfs:label obo:CL_1000307 "fibroblast of dense regular elastic tissue")
EquivalentClasses(obo:CL_1000307 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007846)))
SubClassOf(obo:CL_1000307 obo:CL_0000057)
SubClassOf(obo:CL_1000307 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002521))

# Class: obo:CL_1000308 (fibrocyte of adventitia of ureter)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:28028137") obo:IAO_0000115 obo:CL_1000308 "A stromal cell that is part of the outer adventitial layer of the ureter. This cell type is marked by expression of periostin (POSTN) in mice, and it is derived from Foxd1+ mesenchymal progenitors around embryonic day 12.5. The adventitial fibrocyte initiates differentiation earlier than smooth muscle cells and becomes terminally differentiated by E16.5-18.5 in mice, exhibiting low proliferative capacity in adulthood.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000308 "FMA:261289")
AnnotationAssertion(rdfs:label obo:CL_1000308 "fibrocyte of adventitia of ureter")
SubClassOf(obo:CL_1000308 obo:CL_0000499)
SubClassOf(obo:CL_1000308 obo:CL_0002503)
SubClassOf(obo:CL_1000308 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001252))
SubClassOf(obo:CL_1000308 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013031))

# Class: obo:CL_1000309 (epicardial adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000309 "An adipocyte that is part of the epicardial fat.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000309 "FMA:261293")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261293") oboInOwl:hasExactSynonym obo:CL_1000309 "adipocyte of epicardial fat")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261293") oboInOwl:hasExactSynonym obo:CL_1000309 "epicardial fat cell")
AnnotationAssertion(rdfs:label obo:CL_1000309 "epicardial adipocyte")
SubClassOf(obo:CL_1000309 obo:CL_0000136)
SubClassOf(obo:CL_1000309 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002348))

# Class: obo:CL_1000310 (adipocyte of epicardial fat of right ventricle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000310 "An adipocyte that is part of the epicardial fat of right ventricle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000310 "FMA:261297")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261297") oboInOwl:hasExactSynonym obo:CL_1000310 "epicardial adipocyte of right ventricle")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261297") oboInOwl:hasExactSynonym obo:CL_1000310 "epicardial fat cell of right ventricle")
AnnotationAssertion(rdfs:label obo:CL_1000310 "adipocyte of epicardial fat of right ventricle")
EquivalentClasses(obo:CL_1000310 ObjectIntersectionOf(obo:CL_1000309 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002080)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000310 obo:CL_0000136)
SubClassOf(obo:CL_1000310 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002080))

# Class: obo:CL_1000311 (adipocyte of epicardial fat of left ventricle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000311 "An adipocyte that is part of the epicardial fat of left ventricle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000311 "FMA:261300")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261300") oboInOwl:hasExactSynonym obo:CL_1000311 "epicardial adipocyte of left ventricle")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:261300") oboInOwl:hasExactSynonym obo:CL_1000311 "epicardial fat cell of left ventricle")
AnnotationAssertion(rdfs:label obo:CL_1000311 "adipocyte of epicardial fat of left ventricle")
EquivalentClasses(obo:CL_1000311 ObjectIntersectionOf(obo:CL_1000309 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002084)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000311 obo:CL_0000136)
SubClassOf(obo:CL_1000311 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002084))

# Class: obo:CL_1000312 (bronchial goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000312 "A goblet cell that is part of the epithelium of bronchus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000312 "FMA:263032")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:263032") oboInOwl:hasExactSynonym obo:CL_1000312 "goblet cell of epithelium of bronchus")
AnnotationAssertion(rdfs:label obo:CL_1000312 "bronchial goblet cell")
EquivalentClasses(obo:CL_1000312 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002185)))
SubClassOf(obo:CL_1000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031))

# Class: obo:CL_1000313 (gastric goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000313 "A goblet cell that is part of the epithelium of stomach.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000313 "FMA:263035")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:263035") oboInOwl:hasExactSynonym obo:CL_1000313 "goblet cell of epithelium of stomach")
AnnotationAssertion(rdfs:label obo:CL_1000313 "gastric goblet cell")
EquivalentClasses(obo:CL_1000313 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000945)))
SubClassOf(obo:CL_1000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))

# Class: obo:CL_1000314 (gastric cardiac gland goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000314 "A goblet cell that is part of the epithelium of gastric cardiac gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000314 "FMA:263038")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000314 "goblet cell of epithelium of gastric cardiac gland")
AnnotationAssertion(rdfs:label obo:CL_1000314 "gastric cardiac gland goblet cell")
EquivalentClasses(obo:CL_1000314 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008859)))
SubClassOf(obo:CL_1000314 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))
SubClassOf(obo:CL_1000314 ObjectSomeValuesFrom(obo:BFO_0000050 ObjectIntersectionOf(obo:UBERON_0000483 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008859))))

# Class: obo:CL_1000315 (principal gastric gland goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000315 "A goblet cell that is part of the epithelium of principal gastric gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000315 "FMA:263040")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000315 "goblet cell of epithelium of principal gastric gland")
AnnotationAssertion(rdfs:label obo:CL_1000315 "principal gastric gland goblet cell")
EquivalentClasses(obo:CL_1000315 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009971)))
SubClassOf(obo:CL_1000315 obo:CL_1000313)
SubClassOf(obo:CL_1000315 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))

# Class: obo:CL_1000316 (obsolete goblet cell of epithelium of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000316 "OBSOLETE: A goblet cell that is part of the epithelium of small intestine.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000316 obo:CL_1000495)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000316 "FMA:263042")
AnnotationAssertion(rdfs:label obo:CL_1000316 "obsolete goblet cell of epithelium of small intestine")
AnnotationAssertion(owl:deprecated obo:CL_1000316 "true"^^xsd:boolean)

# Class: obo:CL_1000317 (intestinal villus goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000317 "A goblet cell that is part of the epithelium of intestinal villus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000317 "FMA:263046")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000317 "goblet cell of epithelium of intestinal villus")
AnnotationAssertion(rdfs:label obo:CL_1000317 "intestinal villus goblet cell")
EquivalentClasses(obo:CL_1000317 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013636)))
SubClassOf(obo:CL_1000317 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000318 (obsolete small intestine crypt goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000318 "A goblet cell that is part of the epithelium of crypt of lieberkuhn of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000318 "FMA:263050")
AnnotationAssertion(rdfs:label obo:CL_1000318 "obsolete small intestine crypt goblet cell")
AnnotationAssertion(owl:deprecated obo:CL_1000318 "true"^^xsd:boolean)

# Class: obo:CL_1000319 (obsolete goblet cell of epithelium proper of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000319 "OBSOLETE: A goblet cell that is part of the epithelium proper of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000319 "FMA:263052")
AnnotationAssertion(rdfs:label obo:CL_1000319 "obsolete goblet cell of epithelium proper of small intestine")
AnnotationAssertion(owl:deprecated obo:CL_1000319 "true"^^xsd:boolean)

# Class: obo:CL_1000320 (large intestine goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000320 "A goblet cell that is part of the epithelium of large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000320 "FMA:263054")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000320 "goblet cell of epithelium of large intestine")
AnnotationAssertion(rdfs:label obo:CL_1000320 "large intestine goblet cell")
EquivalentClasses(obo:CL_1000320 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278)))

# Class: obo:CL_1000321 (large intestine crypt goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000321 "A goblet cell that is part of the epithelium of crypt of Lieberkuhn of large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000321 "FMA:263056")
AnnotationAssertion(rdfs:label obo:CL_1000321 "large intestine crypt goblet cell")
EquivalentClasses(obo:CL_1000321 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0022281)))

# Class: obo:CL_1000322 (pancreatic goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000322 "A goblet cell that is part of the epithelium of pancreatic duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000322 "FMA:263058")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:263058") oboInOwl:hasExactSynonym obo:CL_1000322 "goblet cell of epithelium of pancreatic duct")
AnnotationAssertion(rdfs:label obo:CL_1000322 "pancreatic goblet cell")
EquivalentClasses(obo:CL_1000322 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)))
SubClassOf(obo:CL_1000322 obo:CL_0000069)
SubClassOf(obo:CL_1000322 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009970))

# Class: obo:CL_1000323 (pyloric gastric gland goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000323 "A goblet cell that is part of the epithelium of pyloric gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000323 "FMA:263061")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000323 "goblet cell of epithelium of pyloric gland")
AnnotationAssertion(rdfs:label obo:CL_1000323 "pyloric gastric gland goblet cell")
EquivalentClasses(obo:CL_1000323 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008861)))
SubClassOf(obo:CL_1000323 ObjectSomeValuesFrom(obo:BFO_0000050 ObjectIntersectionOf(obo:UBERON_0001276 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008861))))

# Class: obo:CL_1000324 (duodenal goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000324 "A goblet cell that is part of the epithelium proper of duodenum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000324 "FMA:263063")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000324 "goblet cell of epithelium proper of duodenum")
AnnotationAssertion(rdfs:label obo:CL_1000324 "duodenal goblet cell")
EquivalentClasses(obo:CL_1000324 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346)))
SubClassOf(obo:CL_1000324 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902)))

# Class: obo:CL_1000325 (jejunal goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000325 "A goblet cell that is part of the epithelium proper of jejunum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000325 "FMA:263065")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000325 "goblet cell of epithelium proper of jejunum")
AnnotationAssertion(rdfs:label obo:CL_1000325 "jejunal goblet cell")
EquivalentClasses(obo:CL_1000325 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000400)))

# Class: obo:CL_1000326 (ileal goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000326 "A goblet cell that is part of the epithelium proper of ileum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000326 "FMA:263067")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000326 "goblet cell of epithelium proper of ileum")
AnnotationAssertion(rdfs:label obo:CL_1000326 "ileal goblet cell")
EquivalentClasses(obo:CL_1000326 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008345)))
SubClassOf(obo:CL_1000326 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000327 (appendix goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000327 "A goblet cell that is part of the epithelium proper of appendix.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000327 "FMA:263069")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000327 "goblet cell of epithelium proper of appendix")
AnnotationAssertion(rdfs:label obo:CL_1000327 "appendix goblet cell")
EquivalentClasses(obo:CL_1000327 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697)))

# Class: obo:CL_1000328 (obsolete goblet cell of epithelium proper of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000328 "OBSOLETE: A goblet cell that is part of the epithelium proper of large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000328 "FMA:263071")
AnnotationAssertion(rdfs:label obo:CL_1000328 "obsolete goblet cell of epithelium proper of large intestine")
AnnotationAssertion(owl:deprecated obo:CL_1000328 "true"^^xsd:boolean)

# Class: obo:CL_1000329 (tracheal goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000329 "A goblet cell that is part of the epithelium of trachea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000329 "FMA:263075")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:263075") oboInOwl:hasExactSynonym obo:CL_1000329 "goblet cell of epithelium of trachea")
AnnotationAssertion(rdfs:label obo:CL_1000329 "tracheal goblet cell")
EquivalentClasses(obo:CL_1000329 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003126)))
SubClassOf(obo:CL_1000329 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001901))

# Class: obo:CL_1000330 (serous cell of epithelium of trachea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000330 "A serous secreting cell that is part of the epithelium of trachea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000330 "FMA:263078")
AnnotationAssertion(rdfs:label obo:CL_1000330 "serous cell of epithelium of trachea")
EquivalentClasses(obo:CL_1000330 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001901)))

# Class: obo:CL_1000331 (serous cell of epithelium of bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000331 "A serous secreting cell that is part of the epithelium of bronchus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000331 "FMA:263080")
AnnotationAssertion(rdfs:label obo:CL_1000331 "serous cell of epithelium of bronchus")
EquivalentClasses(obo:CL_1000331 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031)))

# Class: obo:CL_1000332 (serous cell of epithelium of terminal bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000332 "A serous secreting cell that is part of the epithelium of terminal bronchiole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000332 "FMA:263082")
AnnotationAssertion(rdfs:label obo:CL_1000332 "serous cell of epithelium of terminal bronchiole")
EquivalentClasses(obo:CL_1000332 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001958)))

# Class: obo:CL_1000333 (serous cell of epithelium of lobular bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000333 "A serous secreting cell that is part of the epithelium of bronchiole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000333 "FMA:263084")
AnnotationAssertion(rdfs:label obo:CL_1000333 "serous cell of epithelium of lobular bronchiole")
EquivalentClasses(obo:CL_1000333 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600001)))

# Class: obo:CL_1000334 (enterocyte of epithelium of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000334 "An enterocyte that is part of the epithelium of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000334 "FMA:263086")
AnnotationAssertion(rdfs:label obo:CL_1000334 "enterocyte of epithelium of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine, including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_1000334 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_1000334 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000334 obo:CL_0000584)

# Class: obo:CL_1000335 (enterocyte of epithelium of intestinal villus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000335 "An enterocyte that is part of the epithelium of intestinal villus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000335 "FMA:263088")
AnnotationAssertion(rdfs:label obo:CL_1000335 "enterocyte of epithelium of intestinal villus")
EquivalentClasses(obo:CL_1000335 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013636)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000335 obo:CL_0000584)
SubClassOf(obo:CL_1000335 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001213))
SubClassOf(obo:CL_1000335 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000336 (obo:CL_1000336)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000336 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000336 obo:CL_1000346)
AnnotationAssertion(owl:deprecated obo:CL_1000336 "true"^^xsd:boolean)

# Class: obo:CL_1000337 (enterocyte of epithelium of duodenal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000337 "An enterocyte that is part of the epithelium of duodenal gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000337 "FMA:263092")
AnnotationAssertion(rdfs:label obo:CL_1000337 "enterocyte of epithelium of duodenal gland")
EquivalentClasses(obo:CL_1000337 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001212)))
SubClassOf(obo:CL_1000337 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000338 (enterocyte of epithelium of crypt of Lieberkuhn of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000338 "An enterocyte that is part of the epithelium of crypt of Lieberkuhn of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000338 "FMA:263094")
AnnotationAssertion(rdfs:label obo:CL_1000338 "enterocyte of epithelium of crypt of Lieberkuhn of small intestine")
SubClassOf(obo:CL_1000338 obo:CL_1000334)
SubClassOf(obo:CL_1000338 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001983))

# Class: obo:CL_1000339 (enterocyte of epithelium proper of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000339 "An enterocyte that is part of the epithelium proper of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000339 "FMA:263096")
AnnotationAssertion(rdfs:label obo:CL_1000339 "enterocyte of epithelium proper of small intestine")
SubClassOf(obo:CL_1000339 obo:CL_1000334)

# Class: obo:CL_1000340 (enterocyte of epithelium proper of duodenum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000340 "An enterocyte that is part of the epithelium proper of duodenum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000340 "FMA:263098")
AnnotationAssertion(rdfs:label obo:CL_1000340 "enterocyte of epithelium proper of duodenum")
SubClassOf(obo:CL_1000340 obo:CL_1000339)
SubClassOf(obo:CL_1000340 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))
SubClassOf(obo:CL_1000340 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114))

# Class: obo:CL_1000341 (enterocyte of epithelium proper of jejunum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000341 "An enterocyte that is part of the epithelium proper of jejunum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000341 "FMA:263100")
AnnotationAssertion(rdfs:label obo:CL_1000341 "enterocyte of epithelium proper of jejunum")
SubClassOf(obo:CL_1000341 obo:CL_1000339)

# Class: obo:CL_1000342 (enterocyte of epithelium proper of ileum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000342 "An enterocyte that is part of the epithelium proper of ileum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000342 "FMA:263102")
AnnotationAssertion(rdfs:label obo:CL_1000342 "enterocyte of epithelium proper of ileum")
SubClassOf(obo:CL_1000342 obo:CL_1000339)

# Class: obo:CL_1000343 (paneth cell of epithelium of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000343 "A paneth cell that is part of the epithelium of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000343 "FMA:263104")
AnnotationAssertion(rdfs:label obo:CL_1000343 "paneth cell of epithelium of small intestine")
AnnotationAssertion(Annotation(dc:license "http://creativecommons.org/licenses/by/4.0/") Annotation(oboInOwl:hasDbXref "doi:10.1186/s13619-020-00061-5") Annotation(rdfs:comment "Figure depicts a cross section of intestinal villi in the small intestine , including the crypts of Lieberkuhn (seen here as ‘crypt’), as well as the layer specific locations of cells that exist within the gastrointestinal tract. Layers depicted here include epithelium (rows of cells bordering villus), submucosa (white space below the epithelium containing networks of neurons and ganglia depicted in pink), muscularis mucosae (blue layer), muscularis propria (referred to here as muscle layer).

ISC: Intestinal Stem Cell 
TA: Transit Amplifying Cells") foaf:depiction obo:CL_1000343 <http://purl.obolibrary.org/obo/cl/images/Small-intestine-cells.png>)
EquivalentClasses(obo:CL_1000343 ObjectIntersectionOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000343 obo:CL_0000510)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000343 obo:CL_0002254)

# Class: obo:CL_1000344 (paneth cell of epithelium proper of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000344 "A Paneth cell that is part of the epithelium proper of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000344 "FMA:263106")
AnnotationAssertion(rdfs:label obo:CL_1000344 "paneth cell of epithelium proper of small intestine")
SubClassOf(obo:CL_1000344 obo:CL_1000343)

# Class: obo:CL_1000345 (paneth cell of epithelium of crypt of Lieberkuhn of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000345 "A paneth cell that is part of the epithelium of crypt of Lieberkuhn of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000345 "FMA:263108")
AnnotationAssertion(rdfs:label obo:CL_1000345 "paneth cell of epithelium of crypt of Lieberkuhn of small intestine")
SubClassOf(obo:CL_1000345 obo:CL_1000343)
SubClassOf(obo:CL_1000345 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001983))

# Class: obo:CL_1000346 (enterocyte of epithelium proper of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000346 "An enterocyte that is part of the epithelium proper of large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000346 "FMA:263090")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000346 "FMA:263112")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_1000346 "vacuolar absorptive cell of epithelium proper of large intestine")
AnnotationAssertion(rdfs:label obo:CL_1000346 "enterocyte of epithelium proper of large intestine")
SubClassOf(obo:CL_1000346 obo:CL_0002071)

# Class: obo:CL_1000347 (colonocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16870803") Annotation(oboInOwl:hasDbXref "PMID:23821742") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_1000347 "An enterocyte (absorptive epithelial cell) of the colonic epithelium, characterized by a columnar shape. This cell is responsible for the absorption, transport, and metabolization of short-chain fatty acids (SCFAs) produced by gut bacteria, as well as the transport and absorption of water and electrolytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000347 "FMA:263114")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000347 "enterocyte of colon")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_1000347 "vacuolar absorptive cell of epithelium of colon")
AnnotationAssertion(rdfs:label obo:CL_1000347 "colonocyte")
EquivalentClasses(obo:CL_1000347 ObjectIntersectionOf(obo:CL_0002071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))
SubClassOf(obo:CL_1000347 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019626))
SubClassOf(obo:CL_1000347 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035377))

# Class: obo:CL_1000348 (basal cell of epithelium of trachea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000348 "A basal cell that is part of the epithelium of trachea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000348 "FMA:263118")
AnnotationAssertion(rdfs:label obo:CL_1000348 "basal cell of epithelium of trachea")
EquivalentClasses(obo:CL_1000348 ObjectIntersectionOf(obo:CL_0002633 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001901)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000348 obo:CL_0002633)

# Class: obo:CL_1000349 (basal cell of epithelium of bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000349 "A basal cell found in the bronchus epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000349 "FMA:263120")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000349 "basal cell of bronchus")
AnnotationAssertion(rdfs:label obo:CL_1000349 "basal cell of epithelium of bronchus")
EquivalentClasses(obo:CL_1000349 ObjectIntersectionOf(obo:CL_0002633 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002031)))
SubClassOf(obo:CL_1000349 obo:CL_0002329)

# Class: obo:CL_1000350 (basal cell of epithelium of terminal bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000350 "A basal cell that is part of the epithelium of terminal bronchiole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000350 "FMA:263122")
AnnotationAssertion(rdfs:label obo:CL_1000350 "basal cell of epithelium of terminal bronchiole")
EquivalentClasses(obo:CL_1000350 ObjectIntersectionOf(obo:CL_0002633 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001958)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000350 obo:CL_0002633)

# Class: obo:CL_1000351 (basal cell of epithelium of respiratory bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000351 "A basal cell that is part of the epithelium of respiratory bronchiole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000351 "FMA:263124")
AnnotationAssertion(rdfs:label obo:CL_1000351 "basal cell of epithelium of respiratory bronchiole")
EquivalentClasses(obo:CL_1000351 ObjectIntersectionOf(obo:CL_0002633 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001955)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000351 obo:CL_0002633)

# Class: obo:CL_1000352 (basal cell of epithelium of lobular bronchiole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000352 "A basal cell that is part of the epithelium of bronchiole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000352 "FMA:263126")
AnnotationAssertion(rdfs:label obo:CL_1000352 "basal cell of epithelium of lobular bronchiole")
EquivalentClasses(obo:CL_1000352 ObjectIntersectionOf(obo:CL_0002633 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600001)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000352 obo:CL_0002633)

# Class: obo:CL_1000353 (microfold cell of epithelium of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000353 "A M cell that is part of the epithelium of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000353 "FMA:263128")
AnnotationAssertion(rdfs:label obo:CL_1000353 "microfold cell of epithelium of small intestine")
EquivalentClasses(obo:CL_1000353 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000353 obo:CL_0000682)
SubClassOf(obo:CL_1000353 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000354 (microfold cell of epithelium of intestinal villus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000354 "A M cell that is part of the epithelium of intestinal villus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000354 "FMA:263130")
AnnotationAssertion(rdfs:label obo:CL_1000354 "microfold cell of epithelium of intestinal villus")
EquivalentClasses(obo:CL_1000354 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001213)))
SubClassOf(obo:CL_1000354 obo:CL_0000682)
SubClassOf(obo:CL_1000354 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))
SubClassOf(obo:CL_1000354 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013636))

# Class: obo:CL_1000355 (microfold cell of epithelium proper of small intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000355 "A M cell that is part of the epithelium proper of small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000355 "FMA:263132")
AnnotationAssertion(rdfs:label obo:CL_1000355 "microfold cell of epithelium proper of small intestine")
SubClassOf(obo:CL_1000355 obo:CL_1000353)

# Class: obo:CL_1000356 (microfold cell of epithelium proper of duodenum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000356 "A M cell that is part of the epithelium proper of duodenum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000356 "FMA:263134")
AnnotationAssertion(rdfs:label obo:CL_1000356 "microfold cell of epithelium proper of duodenum")
EquivalentClasses(obo:CL_1000356 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114)))
SubClassOf(obo:CL_1000356 obo:CL_0000682)
SubClassOf(obo:CL_1000356 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))
SubClassOf(obo:CL_1000356 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346))

# Class: obo:CL_1000357 (microfold cell of epithelium proper of jejunum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000357 "A M cell that is part of the epithelium proper of jejunum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000357 "FMA:263136")
AnnotationAssertion(rdfs:label obo:CL_1000357 "microfold cell of epithelium proper of jejunum")
EquivalentClasses(obo:CL_1000357 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002115)))
SubClassOf(obo:CL_1000357 obo:CL_0000682)

# Class: obo:CL_1000358 (microfold cell of epithelium proper of ileum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000358 "A M cell that is part of the epithelium proper of ileum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000358 "FMA:263138")
AnnotationAssertion(rdfs:label obo:CL_1000358 "microfold cell of epithelium proper of ileum")
EquivalentClasses(obo:CL_1000358 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002116)))
SubClassOf(obo:CL_1000358 obo:CL_0000682)
SubClassOf(obo:CL_1000358 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1000359 (microfold cell of epithelium proper of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000359 "A M cell that is part of the epithelium proper of appendix.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000359 "FMA:263140")
AnnotationAssertion(rdfs:label obo:CL_1000359 "microfold cell of epithelium proper of appendix")
EquivalentClasses(obo:CL_1000359 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))
SubClassOf(obo:CL_1000359 obo:CL_0000682)
SubClassOf(obo:CL_1000359 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697))

# Class: obo:CL_1000360 (microfold cell of epithelium proper of large intestine)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000360 "A M cell that is part of the epithelium proper of large intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000360 "FMA:263142")
AnnotationAssertion(rdfs:label obo:CL_1000360 "microfold cell of epithelium proper of large intestine")
EquivalentClasses(obo:CL_1000360 ObjectIntersectionOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000059)))
SubClassOf(obo:CL_1000360 obo:CL_0000682)
SubClassOf(obo:CL_1000360 obo:CL_0002253)

# Class: obo:CL_1000361 (transitional myocyte of interatrial septum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000361 "A transitional myocyte that is part of the interatrial septum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000361 "FMA:263152")
AnnotationAssertion(rdfs:label obo:CL_1000361 "transitional myocyte of interatrial septum")
EquivalentClasses(obo:CL_1000361 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002085)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000361 obo:CL_0002073)

# Class: obo:CL_1000362 (transitional myocyte of interventricular septum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000362 "A transitional myocyte that is part of the interventricular septum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000362 "FMA:263154")
AnnotationAssertion(rdfs:label obo:CL_1000362 "transitional myocyte of interventricular septum")
EquivalentClasses(obo:CL_1000362 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002094)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000362 obo:CL_0002073)

# Class: obo:CL_1000363 (transitional myocyte of atrial branch of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000363 "A transitional myocyte that is part of the atrial branch of anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000363 "FMA:263156")
AnnotationAssertion(rdfs:label obo:CL_1000363 "transitional myocyte of atrial branch of anterior internodal tract")
SubClassOf(obo:CL_1000363 obo:CL_1000480)

# Class: obo:CL_1000364 (transitional myocyte of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000364 "A transitional myocyte that is part of the anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000364 "FMA:263158")
AnnotationAssertion(rdfs:label obo:CL_1000364 "transitional myocyte of anterior internodal tract")
SubClassOf(obo:CL_1000364 obo:CL_1000480)

# Class: obo:CL_1000365 (transitional myocyte of atrial septal branch of anterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000365 "A transitional myocyte that is part of the atrial septal branch of anterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000365 "FMA:263160")
AnnotationAssertion(rdfs:label obo:CL_1000365 "transitional myocyte of atrial septal branch of anterior internodal tract")
SubClassOf(obo:CL_1000365 obo:CL_1000480)

# Class: obo:CL_1000366 (transitional myocyte of middle internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000366 "A transitional myocyte that is part of the middle internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000366 "FMA:263162")
AnnotationAssertion(rdfs:label obo:CL_1000366 "transitional myocyte of middle internodal tract")
SubClassOf(obo:CL_1000366 obo:CL_1000480)

# Class: obo:CL_1000367 (transitional myocyte of posterior internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000367 "A transitional myocyte that is part of the posterior internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000367 "FMA:263164")
AnnotationAssertion(rdfs:label obo:CL_1000367 "transitional myocyte of posterior internodal tract")
SubClassOf(obo:CL_1000367 obo:CL_1000480)

# Class: obo:CL_1000368 (transitional myocyte of anterior division of left branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000368 "A transitional myocyte that is part of the anterior division of left branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000368 "FMA:263166")
AnnotationAssertion(rdfs:label obo:CL_1000368 "transitional myocyte of anterior division of left branch of atrioventricular bundle")
SubClassOf(obo:CL_1000368 obo:CL_1000481)
SubClassOf(obo:CL_1000368 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986))

# Class: obo:CL_1000369 (transitional myocyte of septal division of left branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000369 "A transitional myocyte that is part of the septal division of left branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000369 "FMA:263168")
AnnotationAssertion(rdfs:label obo:CL_1000369 "transitional myocyte of septal division of left branch of atrioventricular bundle")
SubClassOf(obo:CL_1000369 obo:CL_1000481)
SubClassOf(obo:CL_1000369 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986))

# Class: obo:CL_1000370 (transitional myocyte of left branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000370 "A transitional myocyte that is part of the left branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000370 "FMA:263170")
AnnotationAssertion(rdfs:label obo:CL_1000370 "transitional myocyte of left branch of atrioventricular bundle")
EquivalentClasses(obo:CL_1000370 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986)))
SubClassOf(obo:CL_1000370 obo:CL_1000481)
SubClassOf(obo:CL_1000370 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986))

# Class: obo:CL_1000371 (transitional myocyte of right branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000371 "A transitional myocyte that is part of the right branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000371 "FMA:263172")
AnnotationAssertion(rdfs:label obo:CL_1000371 "transitional myocyte of right branch of atrioventricular bundle")
EquivalentClasses(obo:CL_1000371 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005987)))
SubClassOf(obo:CL_1000371 obo:CL_1000481)
SubClassOf(obo:CL_1000371 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005987))

# Class: obo:CL_1000372 (transitional myocyte of atrial part of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000372 "A transitional myocyte that is part of the atrial part of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000372 "FMA:263174")
AnnotationAssertion(rdfs:label obo:CL_1000372 "transitional myocyte of atrial part of atrioventricular bundle")
SubClassOf(obo:CL_1000372 obo:CL_1000481)

# Class: obo:CL_1000373 (transitional myocyte of ventricular part of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000373 "A transitional myocyte that is part of the ventricular part of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000373 "FMA:263176")
AnnotationAssertion(rdfs:label obo:CL_1000373 "transitional myocyte of ventricular part of atrioventricular bundle")
SubClassOf(obo:CL_1000373 obo:CL_1000481)

# Class: obo:CL_1000374 (transitional myocyte of posterior division of left branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000374 "A transitional myocyte that is part of the posterior division of left branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000374 "FMA:263178")
AnnotationAssertion(rdfs:label obo:CL_1000374 "transitional myocyte of posterior division of left branch of atrioventricular bundle")
SubClassOf(obo:CL_1000374 obo:CL_1000481)
SubClassOf(obo:CL_1000374 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986))

# Class: obo:CL_1000375 (myocardial endocrine cell of septal division of left branch of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000375 "A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000375 "FMA:263180")
AnnotationAssertion(rdfs:label obo:CL_1000375 "myocardial endocrine cell of septal division of left branch of atrioventricular bundle")
SubClassOf(obo:CL_1000375 obo:CL_0002074)
SubClassOf(obo:CL_1000375 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005986))

# Class: obo:CL_1000376 (Purkinje myocyte of interventricular septum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000376 "A Purkinje myocyte that is part of the interventricular septum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000376 "FMA:263182")
AnnotationAssertion(rdfs:label obo:CL_1000376 "Purkinje myocyte of interventricular septum")
EquivalentClasses(obo:CL_1000376 ObjectIntersectionOf(obo:CL_0002068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002094)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000376 obo:CL_0002068)

# Class: obo:CL_1000377 (dense-core granulated cell of epithelium of trachea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000377 "A Feyrter cell that is part of the epithelium of trachea.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000377 "FMA:263184")
AnnotationAssertion(rdfs:label obo:CL_1000377 "dense-core granulated cell of epithelium of trachea")
EquivalentClasses(obo:CL_1000377 ObjectIntersectionOf(obo:CL_0002066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001901)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000377 obo:CL_0000307)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000377 obo:CL_0002066)

# Class: obo:CL_1000378 (type 1 vestibular sensory cell of stato-acoustic epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000378 "A type I vestibular sensory cell that is part of the stato-acoustic epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000378 "FMA:263186")
AnnotationAssertion(rdfs:label obo:CL_1000378 "type 1 vestibular sensory cell of stato-acoustic epithelium")
EquivalentClasses(obo:CL_1000378 ObjectIntersectionOf(obo:CL_0002070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009969)))

# Class: obo:CL_1000379 (type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000379 "A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000379 "FMA:263188")
AnnotationAssertion(rdfs:label obo:CL_1000379 "type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth")
EquivalentClasses(obo:CL_1000379 ObjectIntersectionOf(obo:CL_0002070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002214)))
SubClassOf(obo:CL_1000379 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003241))

# Class: obo:CL_1000380 (type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000380 "A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000380 "FMA:263190")
AnnotationAssertion(rdfs:label obo:CL_1000380 "type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth")
EquivalentClasses(obo:CL_1000380 ObjectIntersectionOf(obo:CL_0002070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002212)))
SubClassOf(obo:CL_1000380 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003242))

# Class: obo:CL_1000381 (type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000381 "A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000381 "FMA:263192")
AnnotationAssertion(rdfs:label obo:CL_1000381 "type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth")
EquivalentClasses(obo:CL_1000381 ObjectIntersectionOf(obo:CL_0002070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006935)))

# Class: obo:CL_1000382 (type 2 vestibular sensory cell of stato-acoustic epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000382 "A type II vestibular sensory cell that is part of the stato-acoustic epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000382 "FMA:263194")
AnnotationAssertion(rdfs:label obo:CL_1000382 "type 2 vestibular sensory cell of stato-acoustic epithelium")
EquivalentClasses(obo:CL_1000382 ObjectIntersectionOf(obo:CL_0002069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009969)))

# Class: obo:CL_1000383 (type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000383 "A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000383 "FMA:263196")
AnnotationAssertion(rdfs:label obo:CL_1000383 "type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth")
EquivalentClasses(obo:CL_1000383 ObjectIntersectionOf(obo:CL_0002069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002214)))
SubClassOf(obo:CL_1000383 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003241))

# Class: obo:CL_1000384 (type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000384 "A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000384 "FMA:263198")
AnnotationAssertion(rdfs:label obo:CL_1000384 "type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth")
EquivalentClasses(obo:CL_1000384 ObjectIntersectionOf(obo:CL_0002069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002212)))
SubClassOf(obo:CL_1000384 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003242))

# Class: obo:CL_1000385 (type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000385 "A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000385 "FMA:263200")
AnnotationAssertion(rdfs:label obo:CL_1000385 "type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth")
EquivalentClasses(obo:CL_1000385 ObjectIntersectionOf(obo:CL_0002069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006935)))

# Class: obo:CL_1000386 (obo:CL_1000386)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000386 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000386 obo:CL_0002205)
AnnotationAssertion(owl:deprecated obo:CL_1000386 "true"^^xsd:boolean)

# Class: obo:CL_1000387 (obo:CL_1000387)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000387 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000387 obo:CL_0002203)
AnnotationAssertion(owl:deprecated obo:CL_1000387 "true"^^xsd:boolean)

# Class: obo:CL_1000388 (obo:CL_1000388)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000388 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000388 obo:CL_0002207)
AnnotationAssertion(owl:deprecated obo:CL_1000388 "true"^^xsd:boolean)

# Class: obo:CL_1000389 (obo:CL_1000389)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000389 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000389 obo:CL_0002208)
AnnotationAssertion(owl:deprecated obo:CL_1000389 "true"^^xsd:boolean)

# Class: obo:CL_1000390 (obo:CL_1000390)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000390 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000390 obo:CL_0002206)
AnnotationAssertion(owl:deprecated obo:CL_1000390 "true"^^xsd:boolean)

# Class: obo:CL_1000391 (melanocyte of eyelid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000391 "A melanocyte that is part of the eyelid.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000391 "FMA:59175")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:59175") oboInOwl:hasExactSynonym obo:CL_1000391 "eyelid melanocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:59175") oboInOwl:hasExactSynonym obo:CL_1000391 "sebaceous gland of wolff")
AnnotationAssertion(rdfs:label obo:CL_1000391 "melanocyte of eyelid")
EquivalentClasses(obo:CL_1000391 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001711)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000391 obo:CL_0000148)

# Class: obo:CL_1000393 (obo:CL_1000393)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000393 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000393 obo:CL_0002543)
AnnotationAssertion(owl:deprecated obo:CL_1000393 "true"^^xsd:boolean)

# Class: obo:CL_1000394 (myoepithelial cell of intralobular lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000394 "A myoepithelial cell that is part of the intralobular part of terminal lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000394 "FMA:62158")
AnnotationAssertion(rdfs:label obo:CL_1000394 "myoepithelial cell of intralobular lactiferous duct")
SubClassOf(obo:CL_1000394 obo:CL_0000185)

# Class: obo:CL_1000395 (obo:CL_1000395)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000395 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000395 obo:CL_0002169)
AnnotationAssertion(owl:deprecated obo:CL_1000395 "true"^^xsd:boolean)

# Class: obo:CL_1000396 (obo:CL_1000396)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000396 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000396 obo:CL_0000362)
AnnotationAssertion(owl:deprecated obo:CL_1000396 "true"^^xsd:boolean)

# Class: obo:CL_1000397 (endothelial cell of venous sinus of red pulp of spleen)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000397 "An endothelial cell that is part of the venous sinus of red pulp of spleen.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000397 "FMA:62817")
AnnotationAssertion(rdfs:comment obo:CL_1000397 "todo - add logical definition to UBERON:0009967")
AnnotationAssertion(rdfs:label obo:CL_1000397 "endothelial cell of venous sinus of red pulp of spleen")
EquivalentClasses(obo:CL_1000397 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009967)))
SubClassOf(obo:CL_1000397 obo:CL_0002651)

# Class: obo:CL_1000398 (endothelial cell of hepatic sinusoid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:3926620") obo:IAO_0000115 obo:CL_1000398 "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000398 "BTO:000125")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000398 "FMA:62911")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30348985") oboInOwl:hasExactSynonym obo:CL_1000398 "LSEC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:62911") oboInOwl:hasExactSynonym obo:CL_1000398 "endotheliocyte of hepatic sinusoid")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30348985") oboInOwl:hasExactSynonym obo:CL_1000398 "liver sinusoidal endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1000398 "endothelial cell of hepatic sinusoid")
EquivalentClasses(obo:CL_1000398 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001281)))
SubClassOf(obo:CL_1000398 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_1000399 (obo:CL_1000399)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000399 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000399 obo:CL_0002178)
AnnotationAssertion(owl:deprecated obo:CL_1000399 "true"^^xsd:boolean)

# Class: obo:CL_1000400 (obo:CL_1000400)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000400 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000400 obo:CL_0002183)
AnnotationAssertion(owl:deprecated obo:CL_1000400 "true"^^xsd:boolean)

# Class: obo:CL_1000401 (obo:CL_1000401)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000401 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000401 obo:CL_0002181)
AnnotationAssertion(owl:deprecated obo:CL_1000401 "true"^^xsd:boolean)

# Class: obo:CL_1000402 (obo:CL_1000402)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000402 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000402 obo:CL_0002252)
AnnotationAssertion(owl:deprecated obo:CL_1000402 "true"^^xsd:boolean)

# Class: obo:CL_1000403 (obo:CL_1000403)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000403 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000403 obo:CL_0002262)
AnnotationAssertion(owl:deprecated obo:CL_1000403 "true"^^xsd:boolean)

# Class: obo:CL_1000404 (obo:CL_1000404)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000404 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000404 obo:CL_0002180)
AnnotationAssertion(owl:deprecated obo:CL_1000404 "true"^^xsd:boolean)

# Class: obo:CL_1000405 (epithelial cell of appendix)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000405 "An epithelial cell that is part of the appendix.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000405 "FMA:63602")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:63602") oboInOwl:hasExactSynonym obo:CL_1000405 "columnar epitheliocyte of appendix")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:63602") oboInOwl:hasExactSynonym obo:CL_1000405 "epithelial cell of vermiform appendix")
AnnotationAssertion(rdfs:label obo:CL_1000405 "epithelial cell of appendix")
EquivalentClasses(obo:CL_1000405 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697)))

# Class: obo:CL_1000406 (obo:CL_1000406)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000406 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000406 obo:CL_0002320)
AnnotationAssertion(owl:deprecated obo:CL_1000406 "true"^^xsd:boolean)

# Class: obo:CL_1000407 (obo:CL_1000407)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000407 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000407 obo:CL_0002202)
AnnotationAssertion(owl:deprecated obo:CL_1000407 "true"^^xsd:boolean)

# Class: obo:CL_1000408 (obo:CL_1000408)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000408 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000408 obo:CL_0002231)
AnnotationAssertion(owl:deprecated obo:CL_1000408 "true"^^xsd:boolean)

# Class: obo:CL_1000409 (myocyte of sinoatrial node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67102") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000409 "A muscle cell that is part of the sinoatrial node.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000409 "FMA:67102")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67102") oboInOwl:hasExactSynonym obo:CL_1000409 "SA nodal myocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_1000409 "SA node cardiac muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_1000409 "sinoatrial node cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000409 "sinoatrial node myocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67102") oboInOwl:hasExactSynonym obo:CL_1000409 "sinuatrial node myocyte")
AnnotationAssertion(rdfs:label obo:CL_1000409 "myocyte of sinoatrial node")
EquivalentClasses(obo:CL_1000409 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002351)))
SubClassOf(obo:CL_1000409 obo:CL_0002072)

# Class: obo:CL_1000410 (myocyte of atrioventricular node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67106") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000410 "A muscle cell that is part of the atrioventricular node.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000410 "FMA:67106")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67106") oboInOwl:hasExactSynonym obo:CL_1000410 "AV nodal myocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_1000410 "AV node cardiac muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_1000410 "AV node cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSynonym obo:CL_1000410 "atrioventricular node cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67106") oboInOwl:hasExactSynonym obo:CL_1000410 "atrioventricular node myocyte")
AnnotationAssertion(rdfs:label obo:CL_1000410 "myocyte of atrioventricular node")
EquivalentClasses(obo:CL_1000410 ObjectIntersectionOf(obo:CL_0000187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002352)))
SubClassOf(obo:CL_1000410 obo:CL_0002072)

# Class: obo:CL_1000411 (endothelial cell of Peyer's patch)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000411 "An endothelial cell that is part of the small intestine Peyer's patch.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000411 "FMA:67757")
AnnotationAssertion(rdfs:label obo:CL_1000411 "endothelial cell of Peyer's patch")
EquivalentClasses(obo:CL_1000411 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003454)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000411 obo:CL_0000115)

# Class: obo:CL_1000412 (endothelial cell of arteriole)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000412 "An endothelial cell that is part of the arteriole.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000412 "FMA:67760")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000412 "KUPO:0001097")
AnnotationAssertion(rdfs:label obo:CL_1000412 "endothelial cell of arteriole")
EquivalentClasses(obo:CL_1000412 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001980)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000412 obo:CL_0000071)

# Class: obo:CL_1000413 (endothelial cell of artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000413 "A blood vessel endothelial cell that is part of an arterial endothelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000413 "BTO:0004758")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000413 "FMA:67761")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000413 "KUPO:0001095")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000413 "arterial endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1000413 "endothelial cell of artery")
EquivalentClasses(obo:CL_1000413 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001637)))
SubClassOf(obo:CL_1000413 obo:CL_0000071)
SubClassOf(obo:CL_1000413 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001917))

# Class: obo:CL_1000414 (endothelial cell of venule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000414 "An endothelial cell that is part of the venule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000414 "FMA:67762")
AnnotationAssertion(rdfs:label obo:CL_1000414 "endothelial cell of venule")
EquivalentClasses(obo:CL_1000414 ObjectIntersectionOf(obo:CL_0002139 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001979)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000414 obo:CL_0002139)

# Class: obo:CL_1000415 (epithelial cell of gallbladder)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000415 "An epithelial cell that is part of the gallbladder.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000415 "FMA:67780")
AnnotationAssertion(rdfs:label obo:CL_1000415 "epithelial cell of gallbladder")
EquivalentClasses(obo:CL_1000415 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002110)))

# Class: obo:CL_1000416 (obsolete myoepithelial cell of lactiferous gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000416 "OBSOLETE. A myoepithelial cell that is part of the mammary gland.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000416 obo:CL_0002324)
AnnotationAssertion(rdfs:comment obo:CL_1000416 "Term merged into CL:0002324 (myoepithelial cell of mammary gland)")
AnnotationAssertion(rdfs:label obo:CL_1000416 "obsolete myoepithelial cell of lactiferous gland")
AnnotationAssertion(owl:deprecated obo:CL_1000416 "true"^^xsd:boolean)

# Class: obo:CL_1000417 (myoepithelial cell of sweat gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000417 "A myoepithelial cell that is part of the sweat gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000417 "FMA:67801")
AnnotationAssertion(rdfs:label obo:CL_1000417 "myoepithelial cell of sweat gland")
EquivalentClasses(obo:CL_1000417 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001820)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000417 obo:CL_0000185)

# Class: obo:CL_1000418 (myoepithelial cell of lactiferous alveolus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000418 "A myoepithelial cell that is part of the mammary gland alveolus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000418 "FMA:67802")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67802") oboInOwl:hasExactSynonym obo:CL_1000418 "basal cell of alveolus of lactiferous gland")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:67802") oboInOwl:hasExactSynonym obo:CL_1000418 "myoepithelial cell of mammary alveolus")
AnnotationAssertion(rdfs:label obo:CL_1000418 "myoepithelial cell of lactiferous alveolus")
EquivalentClasses(obo:CL_1000418 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003214)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000418 obo:CL_0000185)

# Class: obo:CL_1000419 (myoepithelial cell of lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000419 "A myoepithelial cell that is part of the lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000419 "FMA:67803")
AnnotationAssertion(rdfs:label obo:CL_1000419 "myoepithelial cell of lactiferous duct")
EquivalentClasses(obo:CL_1000419 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001765)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000419 obo:CL_0000185)

# Class: obo:CL_1000420 (myoepithelial cell of terminal lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000420 "A myoepithelial cell that is part of the terminal lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000420 "FMA:67804")
AnnotationAssertion(rdfs:label obo:CL_1000420 "myoepithelial cell of terminal lactiferous duct")
SubClassOf(obo:CL_1000420 obo:CL_0000185)

# Class: obo:CL_1000421 (obo:CL_1000421)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000421 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000421 obo:CL_0002138)
AnnotationAssertion(owl:deprecated obo:CL_1000421 "true"^^xsd:boolean)

# Class: obo:CL_1000422 (obo:CL_1000422)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000422 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000422 obo:CL_0000336)
AnnotationAssertion(owl:deprecated obo:CL_1000422 "true"^^xsd:boolean)

# Class: obo:CL_1000423 (obo:CL_1000423)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000423 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000423 obo:CL_0002099)
AnnotationAssertion(owl:deprecated obo:CL_1000423 "true"^^xsd:boolean)

# Class: obo:CL_1000424 (chromaffin cell of paraaortic body)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000424 "A chromaffin cell that is part of the paraaortic body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000424 "FMA:69328")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69328") oboInOwl:hasExactSynonym obo:CL_1000424 "chromaffin cell of para-aortic body")
AnnotationAssertion(rdfs:label obo:CL_1000424 "chromaffin cell of paraaortic body")
EquivalentClasses(obo:CL_1000424 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001237)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000424 obo:CL_0000166)

# Class: obo:CL_1000425 (chromaffin cell of paraganglion)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000425 "A chromaffin cell that is part of the paraganglion.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000425 "FMA:69335")
AnnotationAssertion(rdfs:label obo:CL_1000425 "chromaffin cell of paraganglion")
EquivalentClasses(obo:CL_1000425 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012279)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000425 obo:CL_0000166)

# Class: obo:CL_1000426 (chromaffin cell of adrenal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000426 "A chromaffin cell that is part of the adrenal gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000426 "FMA:69794")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0061104") oboInOwl:hasExactSynonym obo:CL_1000426 "adrenal chromaffin cell")
AnnotationAssertion(rdfs:label obo:CL_1000426 "chromaffin cell of adrenal gland")
EquivalentClasses(obo:CL_1000426 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002369)))
SubClassOf(obo:CL_1000426 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000426 obo:CL_0000166)

# Class: obo:CL_1000427 (adrenal cortex chromaffin cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000427 "A chromaffin cell that is part of the adrenal cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000427 "FMA:69795")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000427 "chromaffin cell of adrenal cortex")
AnnotationAssertion(rdfs:comment obo:CL_1000427 "Not clear this cell type exists. Can't call it a cortical adrenal cell because of different germ layer origin.")
AnnotationAssertion(rdfs:label obo:CL_1000427 "adrenal cortex chromaffin cell")
EquivalentClasses(obo:CL_1000427 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001235)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000427 obo:CL_0000166)

# Class: obo:CL_1000428 (stem cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000428 "A somatic stem cell that is part of the epidermis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000428 "FMA:70541")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70541") oboInOwl:hasExactSynonym obo:CL_1000428 "epidermal stem cell")
AnnotationAssertion(rdfs:label obo:CL_1000428 "stem cell of epidermis")
EquivalentClasses(obo:CL_1000428 ObjectIntersectionOf(obo:CL_0000723 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000428 obo:CL_0000723)

# Class: obo:CL_1000429 (obo:CL_1000429)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000429 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000429 obo:CL_0002260)
AnnotationAssertion(owl:deprecated obo:CL_1000429 "true"^^xsd:boolean)

# Class: obo:CL_1000430 (obo:CL_1000430)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000430 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000430 obo:CL_0000706)
AnnotationAssertion(owl:deprecated obo:CL_1000430 "true"^^xsd:boolean)

# Class: obo:CL_1000431 (obo:CL_1000431)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000431 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000431 obo:CL_0000575)
AnnotationAssertion(owl:deprecated obo:CL_1000431 "true"^^xsd:boolean)

# Class: obo:CL_1000432 (conjunctival epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000432 "An epithelial cell that is part of the conjunctiva.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000432 "FMA:70552")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70552") oboInOwl:hasExactSynonym obo:CL_1000432 "epithelial cell of conjunctiva")
AnnotationAssertion(rdfs:label obo:CL_1000432 "conjunctival epithelial cell")
EquivalentClasses(obo:CL_1000432 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001811)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000432 obo:CL_0000066)

# Class: obo:CL_1000433 (epithelial cell of lacrimal canaliculus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000433 "An epithelial cell that is part of the lacrimal canaliculus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000433 "FMA:70553")
AnnotationAssertion(rdfs:label obo:CL_1000433 "epithelial cell of lacrimal canaliculus")
EquivalentClasses(obo:CL_1000433 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001770)))

# Class: obo:CL_1000434 (epithelial cell of external acoustic meatus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000434 "An epithelial cell that is part of the external acoustic meatus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000434 "FMA:70555")
AnnotationAssertion(rdfs:label obo:CL_1000434 "epithelial cell of external acoustic meatus")
EquivalentClasses(obo:CL_1000434 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001352)))

# Class: obo:CL_1000435 (epithelial cell of lacrimal drainage system)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:22594785") obo:IAO_0000115 obo:CL_1000435 "An epithelial cell that is part of the lacrimal drainage system.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000435 "FMA:70559")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1000435 "epithelial cell of lacrimal duct")
AnnotationAssertion(rdfs:label obo:CL_1000435 "epithelial cell of lacrimal drainage system")
EquivalentClasses(obo:CL_1000435 ObjectIntersectionOf(obo:CL_0000068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001850)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000435 obo:CL_0000072)

# Class: obo:CL_1000436 (epithelial cell of lacrimal sac)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000436 "An epithelial cell that is part of the lacrimal sac.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000436 "FMA:70560")
AnnotationAssertion(rdfs:label obo:CL_1000436 "epithelial cell of lacrimal sac")
EquivalentClasses(obo:CL_1000436 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001351)))

# Class: obo:CL_1000437 (epithelial cell of nasolacrimal duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000437 "An epithelial cell that is part of the nasolacrimal duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000437 "FMA:70561")
AnnotationAssertion(rdfs:label obo:CL_1000437 "epithelial cell of nasolacrimal duct")
EquivalentClasses(obo:CL_1000437 ObjectIntersectionOf(obo:CL_0000072 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002392)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000437 obo:CL_0000072)

# Class: obo:CL_1000438 (epithelial cell of wall of inferior part of anal canal)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000438 "An epithelial cell that is part of the wall of inferior part of anal canal.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000438 "FMA:70562")
AnnotationAssertion(rdfs:label obo:CL_1000438 "epithelial cell of wall of inferior part of anal canal")
SubClassOf(obo:CL_1000438 obo:CL_0002634)
SubClassOf(obo:CL_1000438 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_1000439 (obo:CL_1000439)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000439 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000439 obo:CL_0002187)
AnnotationAssertion(owl:deprecated obo:CL_1000439 "true"^^xsd:boolean)

# Class: obo:CL_1000440 (obo:CL_1000440)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000440 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000440 obo:CL_0002283)
AnnotationAssertion(owl:deprecated obo:CL_1000440 "true"^^xsd:boolean)

# Class: obo:CL_1000441 (epithelial cell of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000441 "An epithelial cell that is part of the viscerocranial mucosa.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000441 "FMA:70583")
AnnotationAssertion(rdfs:label obo:CL_1000441 "epithelial cell of viscerocranial mucosa")
SubClassOf(obo:CL_1000441 obo:CL_0000066)

# Class: obo:CL_1000442 (urothelial cell of trigone of urinary bladder)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000442 "An urothelial cell that is part of the trigone of urinary bladder.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000442 "FMA:70598")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70598") oboInOwl:hasExactSynonym obo:CL_1000442 "epithelial cell of vesical trigone")
AnnotationAssertion(rdfs:label obo:CL_1000442 "urothelial cell of trigone of urinary bladder")
EquivalentClasses(obo:CL_1000442 ObjectIntersectionOf(obo:CL_0000731 ObjectSomeValuesFrom(obo:BFO_0000050 ObjectIntersectionOf(obo:UBERON_0000365 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001257)))))

# Class: obo:CL_1000443 (ciliary muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000443 "A smooth muscle cell that is part of the ciliary body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000443 "FMA:70610")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70610") oboInOwl:hasExactSynonym obo:CL_1000443 "smooth muscle cell of ciliary body")
AnnotationAssertion(rdfs:label obo:CL_1000443 "ciliary muscle cell")
EquivalentClasses(obo:CL_1000443 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001775)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000443 obo:CL_0000192)

# Class: obo:CL_1000444 (mesothelial cell of anterior chamber of eye)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000444 "A mesothelial cell that is part of the anterior chamber of eyeball.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000444 "FMA:70615")
AnnotationAssertion(rdfs:label obo:CL_1000444 "mesothelial cell of anterior chamber of eye")
EquivalentClasses(obo:CL_1000444 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001766)))

# Class: obo:CL_1000445 (myoepithelial cell of dilator pupillae)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000445 "A myoepithelial cell that is part of the dilatator pupillae.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000445 "FMA:70619")
AnnotationAssertion(rdfs:label obo:CL_1000445 "myoepithelial cell of dilator pupillae")
EquivalentClasses(obo:CL_1000445 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001608)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000445 obo:CL_0000185)

# Class: obo:CL_1000446 (obo:CL_1000446)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000446 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000446 obo:CL_0002261)
AnnotationAssertion(owl:deprecated obo:CL_1000446 "true"^^xsd:boolean)

# Class: obo:CL_1000447 (epithelial cell of stratum germinativum of esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000447 "A basal cell that is part of the epithelium of esophagus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000447 "FMA:70731")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70731") oboInOwl:hasExactSynonym obo:CL_1000447 "basal cell of esophageal epithelium")
AnnotationAssertion(rdfs:label obo:CL_1000447 "epithelial cell of stratum germinativum of esophagus")
EquivalentClasses(obo:CL_1000447 ObjectIntersectionOf(obo:CL_0000646 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000447 obo:CL_0000646)

# Class: obo:CL_1000448 (epithelial cell of sweat gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000448 "An epithelial cell that is part of the sweat gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000448 "FMA:70952")
AnnotationAssertion(rdfs:label obo:CL_1000448 "epithelial cell of sweat gland")
EquivalentClasses(obo:CL_1000448 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001820)))

# Class: obo:CL_1000449 (epithelial cell of nephron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000449 "An epithelial cell that is part of the nephron.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000449 "FMA:70965")
AnnotationAssertion(rdfs:label obo:CL_1000449 "epithelial cell of nephron")
EquivalentClasses(obo:CL_1000449 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001285)))

# Class: obo:CL_1000450 (epithelial cell of glomerular capsule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000450 "An epithelial cell that is part of the glomerular capsule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000450 "FMA:70966")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000450 "KUPO:0001034")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000450 "Bowmans capsule epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70966") oboInOwl:hasExactSynonym obo:CL_1000450 "epithelial cell of Bowman's capsule")
AnnotationAssertion(rdfs:label obo:CL_1000450 "epithelial cell of glomerular capsule")
EquivalentClasses(obo:CL_1000450 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001230)))
SubClassOf(obo:CL_1000450 obo:CL_1000510)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000450 obo:CL_1000612)

# Class: obo:CL_1000451 (obsolete epithelial cell of visceral layer of glomerular capsule)

AnnotationAssertion(obo:IAO_0100001 obo:CL_1000451 obo:CL_0000653)
AnnotationAssertion(rdfs:label obo:CL_1000451 "obsolete epithelial cell of visceral layer of glomerular capsule")
AnnotationAssertion(owl:deprecated obo:CL_1000451 "true"^^xsd:boolean)

# Class: obo:CL_1000452 (parietal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000452 "An epithelial cell that is part of the glomerular parietal epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000452 "FMA:70968")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000452 "KUPO:0001035")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70968") oboInOwl:hasExactSynonym obo:CL_1000452 "epithelial cell of parietal layer of glomerular capsule")
AnnotationAssertion(rdfs:label obo:CL_1000452 "parietal epithelial cell")
EquivalentClasses(obo:CL_1000452 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005750)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000452 obo:CL_0000066)

# Class: obo:CL_1000453 (epithelial cell of intermediate tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000453 "An epithelial cell that is part of the intermediate tubule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000453 "FMA:70980")
AnnotationAssertion(rdfs:label obo:CL_1000453 "epithelial cell of intermediate tubule")
EquivalentClasses(obo:CL_1000453 ObjectIntersectionOf(obo:CL_1000494 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004136)))

# Class: obo:CL_1000454 (kidney collecting duct epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000454 "An epithelial cell that is part of the collecting duct of renal tubule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000454 "FMA:70982")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000454 "KUPO:0001059")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70982") oboInOwl:hasExactSynonym obo:CL_1000454 "epithelial cell of renal collecting tubule")
AnnotationAssertion(rdfs:label obo:CL_1000454 "kidney collecting duct epithelial cell")
EquivalentClasses(obo:CL_1000454 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000454 obo:CL_0000072)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000454 obo:CL_0002518)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000454 obo:CL_1001225)

# Class: obo:CL_1000456 (mesothelial cell of parietal peritoneum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000456 "A mesothelial cell that is part of the parietal peritoneum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000456 "FMA:72142")
AnnotationAssertion(rdfs:label obo:CL_1000456 "mesothelial cell of parietal peritoneum")
EquivalentClasses(obo:CL_1000456 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001366)))

# Class: obo:CL_1000457 (mesothelial cell of visceral peritoneum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000457 "A mesothelial cell that is part of the visceral peritoneum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000457 "FMA:72143")
AnnotationAssertion(rdfs:label obo:CL_1000457 "mesothelial cell of visceral peritoneum")
EquivalentClasses(obo:CL_1000457 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001178)))

# Class: obo:CL_1000458 (melanocyte of skin)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000458 "A melanocyte that is part of the skin of body.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000458 "CALOHA:TS-2374")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000458 "FMA:72144")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:72144") oboInOwl:hasExactSynonym obo:CL_1000458 "skin melanocyte")
AnnotationAssertion(rdfs:label obo:CL_1000458 "melanocyte of skin")
EquivalentClasses(obo:CL_1000458 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002097)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000458 obo:CL_0000148)

# Class: obo:CL_1000459 (obo:CL_1000459)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000459 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000459 obo:CL_0002293)
AnnotationAssertion(owl:deprecated obo:CL_1000459 "true"^^xsd:boolean)

# Class: obo:CL_1000461 (obo:CL_1000461)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000461 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000461 obo:CL_0002233)
AnnotationAssertion(owl:deprecated obo:CL_1000461 "true"^^xsd:boolean)

# Class: obo:CL_1000462 (obo:CL_1000462)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000462 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000462 obo:CL_0002232)
AnnotationAssertion(owl:deprecated obo:CL_1000462 "true"^^xsd:boolean)

# Class: obo:CL_1000463 (obo:CL_1000463)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000463 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000463 obo:CL_0002236)
AnnotationAssertion(owl:deprecated obo:CL_1000463 "true"^^xsd:boolean)

# Class: obo:CL_1000464 (obo:CL_1000464)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000464 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000464 obo:CL_0002234)
AnnotationAssertion(owl:deprecated obo:CL_1000464 "true"^^xsd:boolean)

# Class: obo:CL_1000465 (chromaffin cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000465 "A chromaffin cell that is part of the ovary.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000465 "FMA:74319")
AnnotationAssertion(rdfs:label obo:CL_1000465 "chromaffin cell of ovary")
EquivalentClasses(obo:CL_1000465 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000465 obo:CL_0000166)

# Class: obo:CL_1000466 (chromaffin cell of right ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000466 "A chromaffin cell that is part of the right ovary.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000466 "FMA:74320")
AnnotationAssertion(rdfs:label obo:CL_1000466 "chromaffin cell of right ovary")
EquivalentClasses(obo:CL_1000466 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002118)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000466 obo:CL_0000166)

# Class: obo:CL_1000467 (chromaffin cell of left ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000467 "A chromaffin cell that is part of the left ovary.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000467 "FMA:74321")
AnnotationAssertion(rdfs:label obo:CL_1000467 "chromaffin cell of left ovary")
EquivalentClasses(obo:CL_1000467 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002119)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000467 obo:CL_0000166)

# Class: obo:CL_1000468 (myoepithelial cell of acinus of lactiferous gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000468 "A myoepithelial cell that is part of the acinus of lactiferous gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000468 "FMA:74469")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:74469") oboInOwl:hasExactSynonym obo:CL_1000468 "basal cell of acinus of lactiferous gland")
AnnotationAssertion(rdfs:label obo:CL_1000468 "myoepithelial cell of acinus of lactiferous gland")
SubClassOf(obo:CL_1000468 obo:CL_0000185)
SubClassOf(obo:CL_1000468 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001912))

# Class: obo:CL_1000469 (myoepithelial cell of main lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000469 "A myoepithelial cell that is part of the main lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000469 "FMA:74499")
AnnotationAssertion(rdfs:label obo:CL_1000469 "myoepithelial cell of main lactiferous duct")
SubClassOf(obo:CL_1000469 obo:CL_0000185)

# Class: obo:CL_1000470 (myoepithelial cell of primary lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000470 "A myoepithelial cell that is part of the primary lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000470 "FMA:74500")
AnnotationAssertion(rdfs:label obo:CL_1000470 "myoepithelial cell of primary lactiferous duct")
SubClassOf(obo:CL_1000470 obo:CL_0000185)

# Class: obo:CL_1000471 (myoepithelial cell of secondary lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000471 "A myoepithelial cell that is part of the secondary lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000471 "FMA:74501")
AnnotationAssertion(rdfs:label obo:CL_1000471 "myoepithelial cell of secondary lactiferous duct")
SubClassOf(obo:CL_1000471 obo:CL_0000185)

# Class: obo:CL_1000472 (myoepithelial cell of tertiary lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000472 "A myoepithelial cell that is part of the tertiary lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000472 "FMA:74502")
AnnotationAssertion(rdfs:label obo:CL_1000472 "myoepithelial cell of tertiary lactiferous duct")
SubClassOf(obo:CL_1000472 obo:CL_0000185)

# Class: obo:CL_1000473 (myoepithelial cell of quarternary lactiferous duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000473 "A myoepithelial cell that is part of the quarternary lactiferous duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000473 "FMA:74503")
AnnotationAssertion(rdfs:label obo:CL_1000473 "myoepithelial cell of quarternary lactiferous duct")
SubClassOf(obo:CL_1000473 obo:CL_0000185)

# Class: obo:CL_1000474 (obo:CL_1000474)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000474 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000474 obo:CL_0000307)
AnnotationAssertion(owl:deprecated obo:CL_1000474 "true"^^xsd:boolean)

# Class: obo:CL_1000475 (obo:CL_1000475)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000475 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000475 obo:CL_0002350)
AnnotationAssertion(owl:deprecated obo:CL_1000475 "true"^^xsd:boolean)

# Class: obo:CL_1000476 (obo:CL_1000476)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000476 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000476 obo:CL_0002325)
AnnotationAssertion(owl:deprecated obo:CL_1000476 "true"^^xsd:boolean)

# Class: obo:CL_1000477 (cardiac pacemaker cell of sinoatrial node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000477 "A nodal myocyte that is part of the sinoatrial node.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000477 "FMA:83383")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000477 "cardiac pacemaker cell of sinuatrial node")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000477 "pacemaker cell of sinoatrial node")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000477 "pacemaker cell of sinuatrial node")
AnnotationAssertion(rdfs:label obo:CL_1000477 "cardiac pacemaker cell of sinoatrial node")
SubClassOf(obo:CL_1000477 obo:CL_1000409)
SubClassOf(obo:CL_1000477 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002351))

# Class: obo:CL_1000478 (transitional myocyte of sinoatrial node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000478 "A transitional myocyte that is part of the sinoatrial node.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000478 "FMA:83384")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000478 "transitinal myocyte of sinuatrial node")
AnnotationAssertion(rdfs:label obo:CL_1000478 "transitional myocyte of sinoatrial node")
EquivalentClasses(obo:CL_1000478 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002351)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000478 obo:CL_0002073)

# Class: obo:CL_1000479 (Purkinje myocyte of atrioventricular node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000479 "A Purkinje myocyte that is part of the atrioventricular node.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000479 "FMA:83386")
AnnotationAssertion(rdfs:label obo:CL_1000479 "Purkinje myocyte of atrioventricular node")
EquivalentClasses(obo:CL_1000479 ObjectIntersectionOf(obo:CL_0002068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002352)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000479 obo:CL_0002068)

# Class: obo:CL_1000480 (transitional myocyte of internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000480 "A transitional myocyte that is part of the internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000480 "FMA:83387")
AnnotationAssertion(rdfs:label obo:CL_1000480 "transitional myocyte of internodal tract")
EquivalentClasses(obo:CL_1000480 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009966)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000480 obo:CL_0002073)

# Class: obo:CL_1000481 (transitional myocyte of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000481 "A transitional myocyte that is part of the atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000481 "FMA:83388")
AnnotationAssertion(rdfs:label obo:CL_1000481 "transitional myocyte of atrioventricular bundle")
EquivalentClasses(obo:CL_1000481 ObjectIntersectionOf(obo:CL_0002073 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002353)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000481 obo:CL_0002073)

# Class: obo:CL_1000482 (myocardial endocrine cell of interventricular septum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000482 "A myocardial endocrine cell that is part of the interventricular septum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000482 "FMA:83390")
AnnotationAssertion(rdfs:label obo:CL_1000482 "myocardial endocrine cell of interventricular septum")
EquivalentClasses(obo:CL_1000482 ObjectIntersectionOf(obo:CL_0002074 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002094)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000482 obo:CL_0002074)

# Class: obo:CL_1000483 (Purkinje myocyte of internodal tract)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000483 "A Purkinje myocyte that is part of the internodal tract.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000483 "FMA:83392")
AnnotationAssertion(rdfs:label obo:CL_1000483 "Purkinje myocyte of internodal tract")
EquivalentClasses(obo:CL_1000483 ObjectIntersectionOf(obo:CL_0002068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009966)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000483 obo:CL_0002068)

# Class: obo:CL_1000484 (Purkinje myocyte of atrioventricular bundle)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000484 "A Purkinje myocyte that is part of the atrioventricular bundle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000484 "FMA:83393")
AnnotationAssertion(rdfs:label obo:CL_1000484 "Purkinje myocyte of atrioventricular bundle")
EquivalentClasses(obo:CL_1000484 ObjectIntersectionOf(obo:CL_0002068 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002353)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000484 obo:CL_0002068)

# Class: obo:CL_1000486 (basal cell of urothelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") obo:IAO_0000115 obo:CL_1000486 "A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000486 "FMA:84150")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-14366-4_8") Annotation(oboInOwl:hasDbXref "doi:10.1111/cpr.13170") oboInOwl:hasExactSynonym obo:CL_1000486 "urothelial basal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") rdfs:comment obo:CL_1000486 "It has been noted in at least some mammalian species that the urothelial basal cell type is distinguished by expression of high levels of cytokeratin-5 (CK5), p63 and the signalling molecule Sonic hedgehog (Shh). Similar to intermediate cells, the urothelial basal cell type expresses CK17 but is negative for uroplakins (UPK) and CK20. Urothelial basal cells have also been noted to be smaller in diameter than urothelial intermediate cells.")
AnnotationAssertion(rdfs:label obo:CL_1000486 "basal cell of urothelium")
EquivalentClasses(obo:CL_1000486 ObjectIntersectionOf(obo:CL_0000646 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000365)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000486 obo:CL_0000646)
SubClassOf(obo:CL_1000486 obo:CL_0000731)

# Class: obo:CL_1000487 (smooth muscle cell of prostate)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000487 "A smooth muscle cell that is part of the prostate gland.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000487 "FMA:84583")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:84583") oboInOwl:hasExactSynonym obo:CL_1000487 "smooth muscle fiber of prostate")
AnnotationAssertion(rdfs:label obo:CL_1000487 "smooth muscle cell of prostate")
EquivalentClasses(obo:CL_1000487 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000487 obo:CL_0000192)

# Class: obo:CL_1000488 (cholangiocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:16550043") Annotation(oboInOwl:hasDbXref "PMID:18356246") obo:IAO_0000115 obo:CL_1000488 "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000488 "FMA:86481")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000488 "epithelial cell of bile duct")
AnnotationAssertion(rdfs:label obo:CL_1000488 "cholangiocyte")
EquivalentClasses(obo:CL_1000488 ObjectIntersectionOf(obo:CL_0000069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002394) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015106)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000488 obo:CL_0000069)
SubClassOf(obo:CL_1000488 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0005026))
SubClassOf(obo:CL_1000488 ObjectSomeValuesFrom(obo:RO_0002215 ObjectIntersectionOf(obo:GO_0015106 ObjectSomeValuesFrom(obo:BFO_0000050 obo:GO_0032782))))

# Class: obo:CL_1000489 (reticular cell of splenic cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000489 "A reticular cell that is part of the splenic cord.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000489 "FMA:86497")
AnnotationAssertion(rdfs:label obo:CL_1000489 "reticular cell of splenic cord")
EquivalentClasses(obo:CL_1000489 ObjectIntersectionOf(obo:CL_0000432 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001266)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000489 obo:CL_0000432)

# Class: obo:CL_1000490 (mesothelial cell of peritoneum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000490 "A mesothelial cell that is part of the peritoneum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000490 "FMA:86736")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:86736") oboInOwl:hasExactSynonym obo:CL_1000490 "peritoneal mesothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1000490 "mesothelial cell of peritoneum")
EquivalentClasses(obo:CL_1000490 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002358)))

# Class: obo:CL_1000491 (mesothelial cell of pleura)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000491 "A mesothelial cell that is part of the pleura.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000491 "FMA:86737")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:86737") oboInOwl:hasExactSynonym obo:CL_1000491 "pleural mesothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1000491 "mesothelial cell of pleura")
EquivalentClasses(obo:CL_1000491 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000977)))

# Class: obo:CL_1000492 (mesothelial cell of parietal pleura)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000492 "A mesothelial cell that is part of the parietal pleura.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000492 "FMA:86738")
AnnotationAssertion(rdfs:label obo:CL_1000492 "mesothelial cell of parietal pleura")
EquivalentClasses(obo:CL_1000492 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002400)))

# Class: obo:CL_1000493 (mesothelial cell of visceral pleura)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000493 "A mesothelial cell that is part of the visceral pleura.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000493 "FMA:86739")
AnnotationAssertion(rdfs:label obo:CL_1000493 "mesothelial cell of visceral pleura")
EquivalentClasses(obo:CL_1000493 ObjectIntersectionOf(obo:CL_0000077 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002401)))

# Class: obo:CL_1000494 (nephron tubule epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000494 "An epithelial cell that is part of a nephron tubule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000494 "FMA:86785")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000494 "KUPO:0001022")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000494 "kidney tubule epithelial cell")
AnnotationAssertion(rdfs:comment obo:CL_1000494 "This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON.")
AnnotationAssertion(rdfs:label obo:CL_1000494 "nephron tubule epithelial cell")
EquivalentClasses(obo:CL_1000494 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004810)))

# Class: obo:CL_1000495 (small intestine goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1000495 "A goblet cell that is part of the small intestine.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000495 "FMA:86929")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000495 "goblet cell of epithelium of small intestine")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1000495 "goblet cell of small intestine")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:86929") oboInOwl:hasExactSynonym obo:CL_1000495 "small intestinal goblet cell")
AnnotationAssertion(rdfs:label obo:CL_1000495 "small intestine goblet cell")
EquivalentClasses(obo:CL_1000495 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902)))

# Class: obo:CL_1000497 (kidney cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000497 "A cell that is part of a kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000497 "KUPO:0001010")
AnnotationAssertion(rdfs:label obo:CL_1000497 "kidney cell")
EquivalentClasses(obo:CL_1000497 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002113)))

# Class: obo:CL_1000500 (kidney interstitial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000500 "A cell that is part of kidney interstitium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000500 "KUPO:0001013")
AnnotationAssertion(rdfs:label obo:CL_1000500 "kidney interstitial cell")
EquivalentClasses(obo:CL_1000500 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005215)))

# Class: obo:CL_1000504 (kidney medulla cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22343825") obo:IAO_0000115 obo:CL_1000504 "A cell that is part of a renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000504 "KUPO:0001017")
AnnotationAssertion(rdfs:label obo:CL_1000504 "kidney medulla cell")
EquivalentClasses(obo:CL_1000504 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000362)))

# Class: obo:CL_1000505 (kidney pelvis cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000505 "A cell that is part of a renal pelvis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000505 "KUPO:0001018")
AnnotationAssertion(rdfs:label obo:CL_1000505 "kidney pelvis cell")
EquivalentClasses(obo:CL_1000505 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001224)))

# Class: obo:CL_1000507 (kidney tubule cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000507 "A cell that is part of a nephron tubule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000507 "KUPO:0001020")
AnnotationAssertion(rdfs:label obo:CL_1000507 "kidney tubule cell")
EquivalentClasses(obo:CL_1000507 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001231)))

# Class: obo:CL_1000510 (kidney glomerular epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000510 "KUPO:0001023")
AnnotationAssertion(rdfs:label obo:CL_1000510 "kidney glomerular epithelial cell")
EquivalentClasses(obo:CL_1000510 ObjectIntersectionOf(obo:CL_0002518 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004188)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000510 obo:CL_0002518)
SubClassOf(obo:CL_1000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004188))

# Class: obo:CL_1000546 (kidney medulla collecting duct epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000546 "An epithelial cell that is part of a renal medulla collecting duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000546 "KUPO:0001060")
AnnotationAssertion(rdfs:label obo:CL_1000546 "kidney medulla collecting duct epithelial cell")
EquivalentClasses(obo:CL_1000546 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005185)))

# Class: obo:CL_1000547 (kidney inner medulla collecting duct epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000547 "An epithelial cell that is part of some inner medullary collecting duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000547 "KUPO:0001061")
AnnotationAssertion(rdfs:label obo:CL_1000547 "kidney inner medulla collecting duct epithelial cell")
EquivalentClasses(obo:CL_1000547 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004205)))
SubClassOf(obo:CL_1000547 obo:CL_1000546)

# Class: obo:CL_1000548 (kidney outer medulla collecting duct epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000548 "An epithelial cell that is part of an outer medullary collecting duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000548 "KUPO:0001062")
AnnotationAssertion(rdfs:label obo:CL_1000548 "kidney outer medulla collecting duct epithelial cell")
EquivalentClasses(obo:CL_1000548 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004204)))
SubClassOf(obo:CL_1000548 obo:CL_1000546)

# Class: obo:CL_1000549 (kidney cortex collecting duct epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000549 "An epithelial cell that is part of a cortical collecting duct.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000549 "KUPO:0001063")
AnnotationAssertion(rdfs:label obo:CL_1000549 "kidney cortex collecting duct epithelial cell")
EquivalentClasses(obo:CL_1000549 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203)))

# Class: obo:CL_1000550 (kidney papillary duct principal epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000550 "KUPO:0001064")
AnnotationAssertion(rdfs:label obo:CL_1000550 "kidney papillary duct principal epithelial cell")
EquivalentClasses(obo:CL_1000550 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000550 obo:CL_1000497)
SubClassOf(obo:CL_1000550 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167))

# Class: obo:CL_1000596 (inner renal cortex cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000596 "KUPO:0001111")
AnnotationAssertion(rdfs:label obo:CL_1000596 "inner renal cortex cell")
EquivalentClasses(obo:CL_1000596 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005271)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000596 obo:CL_1000497)
SubClassOf(obo:CL_1000596 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005271))

# Class: obo:CL_1000597 (papillary tips cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000597 "A cell that is part of a tip of a renal papilla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000597 "KUPO:0001112")
AnnotationAssertion(rdfs:label obo:CL_1000597 "papillary tips cell")
EquivalentClasses(obo:CL_1000597 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009095)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000597 obo:CL_1000497)
SubClassOf(obo:CL_1000597 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009095))

# Class: obo:CL_1000600 (lower urinary tract cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000600 "KUPO:0001115")
AnnotationAssertion(rdfs:label obo:CL_1000600 "lower urinary tract cell")
EquivalentClasses(obo:CL_1000600 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001556)))
SubClassOf(obo:CL_1000600 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001556))

# Class: obo:CL_1000601 (ureteral cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000601 "KUPO:0001116")
AnnotationAssertion(rdfs:label obo:CL_1000601 "ureteral cell")
EquivalentClasses(obo:CL_1000601 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000056)))
SubClassOf(obo:CL_1000601 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000056))

# Class: obo:CL_1000606 (kidney nerve cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000606 "KUPO:0001015")
AnnotationAssertion(rdfs:label obo:CL_1000606 "kidney nerve cell")
EquivalentClasses(obo:CL_1000606 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002113)))
SubClassOf(obo:CL_1000606 obo:CL_1000500)
SubClassOf(obo:CL_1000606 obo:CL_2000032)

# Class: obo:CL_1000612 (kidney corpuscule cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000612 "KUPO:0001021")
AnnotationAssertion(rdfs:label obo:CL_1000612 "kidney corpuscule cell")
EquivalentClasses(obo:CL_1000612 ObjectIntersectionOf(obo:CL_0002584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001229)))

# Class: obo:CL_1000615 (kidney cortex tubule cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000615 "KUPO:0001024")
AnnotationAssertion(rdfs:label obo:CL_1000615 "kidney cortex tubule cell")
EquivalentClasses(obo:CL_1000615 ObjectIntersectionOf(obo:CL_1000507 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006853)))
SubClassOf(obo:CL_1000615 obo:CL_0002584)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000615 obo:CL_1000507)
SubClassOf(obo:CL_1000615 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006853))

# Class: obo:CL_1000616 (kidney outer medulla cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000616 "KUPO:0001025")
AnnotationAssertion(rdfs:label obo:CL_1000616 "kidney outer medulla cell")
EquivalentClasses(obo:CL_1000616 ObjectIntersectionOf(obo:CL_1000504 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001293)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000616 obo:CL_1000504)
SubClassOf(obo:CL_1000616 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001293))

# Class: obo:CL_1000617 (kidney inner medulla cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000617 "KUPO:0001026")
AnnotationAssertion(rdfs:label obo:CL_1000617 "kidney inner medulla cell")
EquivalentClasses(obo:CL_1000617 ObjectIntersectionOf(obo:CL_1000504 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001294)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000617 obo:CL_1000504)
SubClassOf(obo:CL_1000617 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001294))

# Class: obo:CL_1000618 (juxtaglomerular complex cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000618 "KUPO:0001028")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0072052") oboInOwl:hasExactSynonym obo:CL_1000618 "juxtaglomerulus cell")
AnnotationAssertion(rdfs:label obo:CL_1000618 "juxtaglomerular complex cell")
EquivalentClasses(obo:CL_1000618 ObjectIntersectionOf(obo:CL_0002681 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002303)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000618 obo:CL_0002681)
SubClassOf(obo:CL_1000618 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002303))

# Class: obo:CL_1000681 (kidney cortex interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18575881") obo:IAO_0000115 obo:CL_1000681 "A cell that is part of an interstitial compartment of a renal cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000681 "KUPO:0001091")
AnnotationAssertion(rdfs:label obo:CL_1000681 "kidney cortex interstitial cell")
EquivalentClasses(obo:CL_1000681 ObjectIntersectionOf(obo:CL_1000500 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005270)))
SubClassOf(obo:CL_1000681 obo:CL_0002584)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000681 obo:CL_1000500)
SubClassOf(obo:CL_1000681 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005270))

# Class: obo:CL_1000682 (kidney medulla interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21359760") obo:IAO_0000115 obo:CL_1000682 "A cell that is part of an interstitum of a renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000682 "KUPO:0001092")
AnnotationAssertion(rdfs:label obo:CL_1000682 "kidney medulla interstitial cell")
EquivalentClasses(obo:CL_1000682 ObjectIntersectionOf(obo:CL_1000500 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005211)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000682 obo:CL_1000500)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000682 obo:CL_1000504)
SubClassOf(obo:CL_1000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005211))

# Class: obo:CL_1000691 (kidney interstitial myofibroblast)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000691 "KUPO:0001101")
AnnotationAssertion(rdfs:label obo:CL_1000691 "kidney interstitial myofibroblast")
SubClassOf(obo:CL_1000691 obo:CL_0000186)
SubClassOf(obo:CL_1000691 obo:CL_1000500)

# Class: obo:CL_1000692 (kidney interstitial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10559635") obo:IAO_0000115 obo:CL_1000692 "A fibroblast that is part of an interstitial compartment of a kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000692 "KUPO:0001102")
AnnotationAssertion(rdfs:label obo:CL_1000692 "kidney interstitial fibroblast")
EquivalentClasses(obo:CL_1000692 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005215)))

# Class: obo:CL_1000693 (kidney interstitial fibrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23486523") Annotation(oboInOwl:hasDbXref "PMID:27262400") Annotation(oboInOwl:hasDbXref "PMID:35703942") obo:IAO_0000115 obo:CL_1000693 "A stromal cell that infiltrates and resides in the kidney interstitium following injury, characterized by the co-expression of CD45 with mesenchymal markers including α-SMA, and collagen I in humans (Kim et al., 2023). This cell originates from circulating monocyte-derived fibrocytes. It produces extracellular matrix components, contributing to renal fibrosis by potentially differentiating into myofibroblasts upon infiltration into injured kidneys (Sun et al., 2016). Migration into the kidney is dependent on chemokine receptor signaling, particularly CCR2 in mice (Reich et al., 2013).")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35703942") oboInOwl:hasBroadSynonym obo:CL_1000693 "renal fibrocyte")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000693 "KUPO:0001103")
AnnotationAssertion(rdfs:label obo:CL_1000693 "kidney interstitial fibrocyte")
SubClassOf(obo:CL_1000693 obo:CL_0000499)
SubClassOf(obo:CL_1000693 obo:CL_1000500)
SubClassOf(obo:CL_1000693 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000135))

# Class: obo:CL_1000695 (kidney interstitial alternatively activated macrophage)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000695 "KUPO:0001106")
AnnotationAssertion(rdfs:label obo:CL_1000695 "kidney interstitial alternatively activated macrophage")
SubClassOf(obo:CL_1000695 obo:CL_0000890)
SubClassOf(obo:CL_1000695 obo:CL_1000500)

# Class: obo:CL_1000696 (kidney interstitial inflammatory macrophage)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000696 "KUPO:0001107")
AnnotationAssertion(rdfs:label obo:CL_1000696 "kidney interstitial inflammatory macrophage")
SubClassOf(obo:CL_1000696 obo:CL_0000863)
SubClassOf(obo:CL_1000696 obo:CL_1000500)

# Class: obo:CL_1000697 (kidney interstitial suppressor macrophage)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000697 "KUPO:0001108")
AnnotationAssertion(rdfs:label obo:CL_1000697 "kidney interstitial suppressor macrophage")
SubClassOf(obo:CL_1000697 obo:CL_0000862)
SubClassOf(obo:CL_1000697 obo:CL_1000500)

# Class: obo:CL_1000698 (kidney resident macrophage)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000698 "A tissue-resident macrophage that is part of some kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000698 "KUPO:0001109")
AnnotationAssertion(rdfs:label obo:CL_1000698 "kidney resident macrophage")
SubClassOf(obo:CL_1000698 obo:CL_0000864)
SubClassOf(obo:CL_1000698 obo:CL_1000500)

# Class: obo:CL_1000699 (kidney resident dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25266210") obo:IAO_0000115 obo:CL_1000699 "A resident-dendritic cell that is part of a kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000699 "KUPO:0001110")
AnnotationAssertion(rdfs:label obo:CL_1000699 "kidney resident dendritic cell")
SubClassOf(obo:CL_1000699 obo:CL_0001007)
SubClassOf(obo:CL_1000699 obo:CL_1000500)

# Class: obo:CL_1000702 (kidney pelvis smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000702 "KUPO:0001113")
AnnotationAssertion(rdfs:label obo:CL_1000702 "kidney pelvis smooth muscle cell")
EquivalentClasses(obo:CL_1000702 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004227)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000702 obo:CL_0000192)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000702 obo:CL_1000505)
SubClassOf(obo:CL_1000702 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004227))

# Class: obo:CL_1000703 (kidney pelvis urothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000703 "KUPO:0001114")
AnnotationAssertion(rdfs:label obo:CL_1000703 "kidney pelvis urothelial cell")
EquivalentClasses(obo:CL_1000703 ObjectIntersectionOf(obo:CL_0002518 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004788)))
SubClassOf(obo:CL_1000703 obo:CL_0000731)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000703 obo:CL_0002518)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000703 obo:CL_1000505)
SubClassOf(obo:CL_1000703 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004788))

# Class: obo:CL_1000706 (ureter urothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36180582") obo:IAO_0000115 obo:CL_1000706 "A urothelial cell that is part of the urothelium of ureter.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000706 "KUPO:0001117")
AnnotationAssertion(rdfs:label obo:CL_1000706 "ureter urothelial cell")
EquivalentClasses(obo:CL_1000706 ObjectIntersectionOf(obo:CL_0000731 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001254)))

# Class: obo:CL_1000708 (ureter adventitial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000708 "KUPO:0001119")
AnnotationAssertion(rdfs:label obo:CL_1000708 "ureter adventitial cell")
EquivalentClasses(obo:CL_1000708 ObjectIntersectionOf(obo:CL_1000601 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001252)))
SubClassOf(obo:CL_1000708 obo:CL_0000115)
SubClassOf(obo:CL_1000708 obo:CL_0002503)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000708 obo:CL_1000601)
SubClassOf(obo:CL_1000708 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001252))

# Class: obo:CL_1000714 (kidney cortex collecting duct principal cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000714 "KUPO:0001130")
AnnotationAssertion(rdfs:label obo:CL_1000714 "kidney cortex collecting duct principal cell")
EquivalentClasses(obo:CL_1000714 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000714 obo:CL_0005009)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000714 obo:CL_1000549)
SubClassOf(obo:CL_1000714 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203))

# Class: obo:CL_1000715 (kidney cortex collecting duct intercalated cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000715 "KUPO:0001131")
AnnotationAssertion(rdfs:label obo:CL_1000715 "kidney cortex collecting duct intercalated cell")
EquivalentClasses(obo:CL_1000715 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000715 obo:CL_0005010)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000715 obo:CL_1000549)
SubClassOf(obo:CL_1000715 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203))

# Class: obo:CL_1000716 (kidney outer medulla collecting duct principal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") obo:IAO_0000115 obo:CL_1000716 "Principal cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may express the epithelial sodium channel (ENaC).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000716 "KUPO:0001132")
AnnotationAssertion(rdfs:label obo:CL_1000716 "kidney outer medulla collecting duct principal cell")
EquivalentClasses(obo:CL_1000716 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004204)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000716 obo:CL_0005009)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000716 obo:CL_1000548)
SubClassOf(obo:CL_1000716 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004204))

# Class: obo:CL_1000717 (kidney outer medulla collecting duct intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") obo:IAO_0000115 obo:CL_1000717 "Intercalated cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may contribute in the maintenance of acid/base homeostasis.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000717 "KUPO:0001133")
AnnotationAssertion(rdfs:label obo:CL_1000717 "kidney outer medulla collecting duct intercalated cell")
EquivalentClasses(obo:CL_1000717 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004204)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000717 obo:CL_0005010)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000717 obo:CL_1000548)
SubClassOf(obo:CL_1000717 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004204))

# Class: obo:CL_1000718 (kidney inner medulla collecting duct principal cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000718 "KUPO:0001134")
AnnotationAssertion(rdfs:label obo:CL_1000718 "kidney inner medulla collecting duct principal cell")
EquivalentClasses(obo:CL_1000718 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004205)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000718 obo:CL_0005009)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000718 obo:CL_1000547)
SubClassOf(obo:CL_1000718 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004205))

# Class: obo:CL_1000719 (kidney inner medulla collecting duct intercalated cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000719 "KUPO:0001135")
AnnotationAssertion(rdfs:label obo:CL_1000719 "kidney inner medulla collecting duct intercalated cell")
EquivalentClasses(obo:CL_1000719 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004205)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000719 obo:CL_0005010)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000719 obo:CL_1000547)
SubClassOf(obo:CL_1000719 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004205))

# Class: obo:CL_1000720 (kidney papillary duct intercalated cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000720 "KUPO:0001136")
AnnotationAssertion(rdfs:label obo:CL_1000720 "kidney papillary duct intercalated cell")
EquivalentClasses(obo:CL_1000720 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000720 obo:CL_0005010)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000720 obo:CL_1000550)
SubClassOf(obo:CL_1000720 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167))

# Class: obo:CL_1000721 (kidney papillary duct principal cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000721 "KUPO:0001137")
AnnotationAssertion(rdfs:label obo:CL_1000721 "kidney papillary duct principal cell")
EquivalentClasses(obo:CL_1000721 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000721 obo:CL_0005009)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000721 obo:CL_1000550)
SubClassOf(obo:CL_1000721 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005167))

# Class: obo:CL_1000742 (glomerular mesangial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1152/physrev.1998.78.3.723>) Annotation(oboInOwl:hasDbXref "Wikipedia:Intraglomerular_mesangial_cell") obo:IAO_0000115 obo:CL_1000742 "A mesangial cell located among the glomerular capillaries in a renal corpuscle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000742 "KUPO:0001032")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:cjm") oboInOwl:hasExactSynonym obo:CL_1000742 "intraglomerular mesangial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9127003") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1152/physrev.1998.78.3.723") rdfs:comment obo:CL_1000742 "Like smooth muscle, a glomerular mesangial cell is contractile and possesses the filaments actin and myosin. The contractile mechanism is also similar to that of smooth muscle, with Ca2+/calmodulin-activated myosin light-chain kinase instigating myosin-actin cross-bridge cycling. Mesangial cell phagocytosis of apoptotic neutrophils involves a novel CD36-independent, alpha(v)beta3/TSP-mediated mechanism that is uncoupled from chemokine secretion, emphasizing the injury-limiting potential of mesangial cell phagocytosis of apoptotic cells.")
AnnotationAssertion(rdfs:label obo:CL_1000742 "glomerular mesangial cell")
SubClassOf(obo:CL_1000742 obo:CL_0000650)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000742 obo:CL_1000612)
SubClassOf(obo:CL_1000742 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002320))
SubClassOf(obo:CL_1000742 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909))
SubClassOf(obo:CL_1000742 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070252))

# Class: obo:CL_1000746 (glomerular cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000746 "KUPO:0001036")
AnnotationAssertion(rdfs:label obo:CL_1000746 "glomerular cell")
EquivalentClasses(obo:CL_1000746 ObjectIntersectionOf(obo:CL_1000612 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000074)))

# Class: obo:CL_1000768 (kidney connecting tubule epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000768 "KUPO:0001058")
AnnotationAssertion(rdfs:label obo:CL_1000768 "kidney connecting tubule epithelial cell")
EquivalentClasses(obo:CL_1000768 ObjectIntersectionOf(obo:CL_1000494 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000768 obo:CL_1000494)
SubClassOf(obo:CL_1000768 obo:CL_1000615)
SubClassOf(obo:CL_1000768 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097))

# Class: obo:CL_1000803 (kidney inner medulla interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21359760") obo:IAO_0000115 obo:CL_1000803 "A cell that is part of an interstitial compartment of an inner renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000803 "KUPO:0001093")
AnnotationAssertion(rdfs:label obo:CL_1000803 "kidney inner medulla interstitial cell")
EquivalentClasses(obo:CL_1000803 ObjectIntersectionOf(obo:CL_1000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005214)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000803 obo:CL_1000617)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000803 obo:CL_1000682)
SubClassOf(obo:CL_1000803 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005214))

# Class: obo:CL_1000804 (kidney outer medulla interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8694267") obo:IAO_0000115 obo:CL_1000804 "A kidney cell that is part of an interstitial compartment of an outer renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000804 "KUPO:0001094")
AnnotationAssertion(rdfs:label obo:CL_1000804 "kidney outer medulla interstitial cell")
EquivalentClasses(obo:CL_1000804 ObjectIntersectionOf(obo:CL_1000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005213)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000804 obo:CL_1000616)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000804 obo:CL_1000682)
SubClassOf(obo:CL_1000804 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005213))

# Class: obo:CL_1000838 (kidney proximal convoluted tubule epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000838 "KUPO:0001045")
AnnotationAssertion(rdfs:label obo:CL_1000838 "kidney proximal convoluted tubule epithelial cell")
EquivalentClasses(obo:CL_1000838 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001287) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000838 obo:CL_0002306)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000838 obo:CL_1000615)

# Class: obo:CL_1000839 (kidney proximal straight tubule epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000839 "KUPO:0001046")
AnnotationAssertion(rdfs:label obo:CL_1000839 "kidney proximal straight tubule epithelial cell")
EquivalentClasses(obo:CL_1000839 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001290)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_0002306)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_1000615)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_1000616)

# Class: obo:CL_1000849 (kidney distal convoluted tubule epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000849 "KUPO:0001056")
AnnotationAssertion(rdfs:label obo:CL_1000849 "kidney distal convoluted tubule epithelial cell")
EquivalentClasses(obo:CL_1000849 ObjectIntersectionOf(obo:CL_0002305 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001292)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000849 obo:CL_0002305)
SubClassOf(obo:CL_1000849 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001292))

# Class: obo:CL_1000850 (macula densa epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33491562") Annotation(oboInOwl:hasDbXref "PMID:36142420") Annotation(oboInOwl:hasDbXref "Wikipedia:Macula_densa") obo:IAO_0000115 obo:CL_1000850 "An epithelial cell that is part of the macula densa, characterized by a tightly packed arrangement, apically positioned nuclei, and prominent primary cilia, creating a distinctive 'dense spot' appearance under microscopy. It is involved in regulating renal blood flow, glomerular filtration rate, and renin release.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000850 "KUPO:0001057")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33491562") oboInOwl:hasExactSynonym obo:CL_1000850 "macula densa cell")
AnnotationAssertion(rdfs:label obo:CL_1000850 "macula densa epithelial cell")
EquivalentClasses(obo:CL_1000850 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002335)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000850 obo:CL_0002584)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000850 obo:CL_1000618)
SubClassOf(obo:CL_1000850 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0097730))
SubClassOf(obo:CL_1000850 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0003093))
SubClassOf(obo:CL_1000850 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_1900133))

# Class: obo:CL_1000854 (kidney blood vessel cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34843404") obo:IAO_0000115 obo:CL_1000854 "A blood vessel cell that is part of a kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000854 "KUPO:0001014")
AnnotationAssertion(rdfs:label obo:CL_1000854 "kidney blood vessel cell")
EquivalentClasses(obo:CL_1000854 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003517)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000854 obo:CL_1000504)
SubClassOf(obo:CL_1000854 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003517))
SubClassOf(obo:CL_1000854 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0008015))

# Class: obo:CL_1000891 (kidney arterial blood vessel cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000891 "KUPO:0001029")
AnnotationAssertion(rdfs:label obo:CL_1000891 "kidney arterial blood vessel cell")
EquivalentClasses(obo:CL_1000891 ObjectIntersectionOf(obo:CL_1000854 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003644)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000891 obo:CL_1000854)
SubClassOf(obo:CL_1000891 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003644))

# Class: obo:CL_1000892 (kidney capillary endothelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1000892 "An endothelial cell that is part of the capillary of the kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000892 "KUPO:0001030")
AnnotationAssertion(rdfs:label obo:CL_1000892 "kidney capillary endothelial cell")
EquivalentClasses(obo:CL_1000892 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003527)))
SubClassOf(obo:CL_1000892 obo:CL_0002144)

# Class: obo:CL_1000893 (kidney venous blood vessel cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000893 "KUPO:0001031")
AnnotationAssertion(rdfs:label obo:CL_1000893 "kidney venous blood vessel cell")
EquivalentClasses(obo:CL_1000893 ObjectIntersectionOf(obo:CL_1000854 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001140)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000893 obo:CL_1000854)
SubClassOf(obo:CL_1000893 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001140))

# Class: obo:CL_1000897 (obo:CL_1000897)

AnnotationAssertion(obo:IAO_0000231 obo:CL_1000897 obo:IAO_0000227)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1000897 obo:CL_1000452)
AnnotationAssertion(owl:deprecated obo:CL_1000897 "true"^^xsd:boolean)

# Class: obo:CL_1000909 (kidney loop of Henle epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000909 "KUPO:0001047")
AnnotationAssertion(rdfs:label obo:CL_1000909 "kidney loop of Henle epithelial cell")
EquivalentClasses(obo:CL_1000909 ObjectIntersectionOf(obo:CL_1000494 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001288)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000909 obo:CL_1000494)
SubClassOf(obo:CL_1000909 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001288))

# Class: obo:CL_1000979 (ureter smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000979 "KUPO:0001118")
AnnotationAssertion(rdfs:label obo:CL_1000979 "ureter smooth muscle cell")
EquivalentClasses(obo:CL_1000979 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006855)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000979 obo:CL_0000192)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000979 obo:CL_1000601)
SubClassOf(obo:CL_1000979 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006855))

# Class: obo:CL_1001005 (glomerular capillary endothelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001005 "An endothelial cell that is part of the glomerular capillary of the kidney.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001005 "KUPO:0001037")
AnnotationAssertion(rdfs:label obo:CL_1001005 "glomerular capillary endothelial cell")
EquivalentClasses(obo:CL_1001005 ObjectIntersectionOf(obo:CL_1000892 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004294)))

# Class: obo:CL_1001006 (kidney afferent arteriole cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16990493") Annotation(oboInOwl:hasDbXref "PMID:22733355") Annotation(oboInOwl:hasDbXref "PMID:24066938") Annotation(oboInOwl:hasDbXref "PMID:25834230") obo:IAO_0000115 obo:CL_1001006 "An endothelial cell which is part of the afferent arteriole in the kidney. This cell is  responsible for maintaining renal blood flow and glomerular filtration rate.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001006 "KUPO:0001038")
AnnotationAssertion(rdfs:label obo:CL_1001006 "kidney afferent arteriole cell")
EquivalentClasses(obo:CL_1001006 ObjectIntersectionOf(obo:CL_1000891 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004639)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001006 obo:CL_1000891)
SubClassOf(obo:CL_1001006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004639))

# Class: obo:CL_1001009 (kidney efferent arteriole cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001009 "KUPO:0001041")
AnnotationAssertion(rdfs:label obo:CL_1001009 "kidney efferent arteriole cell")
EquivalentClasses(obo:CL_1001009 ObjectIntersectionOf(obo:CL_1000891 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004640)))

# Class: obo:CL_1001016 (kidney loop of Henle ascending limb epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001016 "KUPO:0001048")
AnnotationAssertion(rdfs:label obo:CL_1001016 "kidney loop of Henle ascending limb epithelial cell")
EquivalentClasses(obo:CL_1001016 ObjectIntersectionOf(obo:CL_1000909 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005164)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001016 obo:CL_1000909)
SubClassOf(obo:CL_1001016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005164))

# Class: obo:CL_1001021 (kidney loop of Henle descending limb epithelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001021 "KUPO:0001053")
AnnotationAssertion(rdfs:label obo:CL_1001021 "kidney loop of Henle descending limb epithelial cell")
EquivalentClasses(obo:CL_1001021 ObjectIntersectionOf(obo:CL_1000909 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001289)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001021 obo:CL_1000909)
SubClassOf(obo:CL_1001021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001289))

# Class: obo:CL_1001033 (peritubular capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19129259") obo:IAO_0000115 obo:CL_1001033 "An endothelial cell that is part of the peritubular capillary of the kidney. This cell is highly fenestrated and plays a vital role in the kidney's filtration process, enabling the exchange of materials between the blood and the renal tubules.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001033 "KUPO:0001065")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19129259") rdfs:comment obo:CL_1001033 "Peritubular capillary endothelial cells feature fenestrations measuring 60-70 nm in diameter, each traversed by a thin diaphragm.")
AnnotationAssertion(rdfs:label obo:CL_1001033 "peritubular capillary endothelial cell")
EquivalentClasses(obo:CL_1001033 ObjectIntersectionOf(obo:CL_1000892 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012441)))
SubClassOf(obo:CL_1001033 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_1001036 (vasa recta cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12529271") Annotation(oboInOwl:hasDbXref "PMID:24381184") obo:IAO_0000115 obo:CL_1001036 "A cell that is part of a vasa recta.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001036 "KUPO:0001068")
AnnotationAssertion(rdfs:label obo:CL_1001036 "vasa recta cell")
EquivalentClasses(obo:CL_1001036 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004726)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001036 obo:CL_1000504)

# Class: obo:CL_1001045 (kidney cortex artery cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001045 "KUPO:0001077")
AnnotationAssertion(rdfs:label obo:CL_1001045 "kidney cortex artery cell")
EquivalentClasses(obo:CL_1001045 ObjectIntersectionOf(obo:CL_1000891 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005268)))
SubClassOf(obo:CL_1001045 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005268))

# Class: obo:CL_1001052 (kidney cortex vein cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001052 "KUPO:0001084")
AnnotationAssertion(rdfs:label obo:CL_1001052 "kidney cortex vein cell")
EquivalentClasses(obo:CL_1001052 ObjectIntersectionOf(obo:CL_1000893 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005269)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001052 obo:CL_1000893)
SubClassOf(obo:CL_1001052 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005269))

# Class: obo:CL_1001064 (kidney artery smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001064 "KUPO:0001096")
AnnotationAssertion(rdfs:comment obo:CL_1001064 "Note that the source of this term is KUPO:0001096 (artery smooth muscle cell), which we believe actually denotes the kidney specific structure.")
AnnotationAssertion(rdfs:label obo:CL_1001064 "kidney artery smooth muscle cell")
SubClassOf(obo:CL_1001064 obo:CL_0000192)
SubClassOf(obo:CL_1001064 obo:CL_1000891)

# Class: obo:CL_1001066 (kidney arteriole smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001066 "KUPO:0001098")
AnnotationAssertion(rdfs:comment obo:CL_1001066 "Note that the source of this term is KUPO:0001098 (arteriole smooth muscle cell), which we believe actually denotes the kidney specific structure.")
AnnotationAssertion(rdfs:label obo:CL_1001066 "kidney arteriole smooth muscle cell")
SubClassOf(obo:CL_1001066 obo:CL_0000192)
SubClassOf(obo:CL_1001066 obo:CL_1000891)

# Class: obo:CL_1001068 (kidney venous system smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001068 "KUPO:0001100")
AnnotationAssertion(rdfs:comment obo:CL_1001068 "Note that the source of this term is KUPO:0001068 (venous system smooth muscle cell), which we believe actually denotes the kidney specific structure.")
AnnotationAssertion(rdfs:label obo:CL_1001068 "kidney venous system smooth muscle cell")
SubClassOf(obo:CL_1001068 obo:CL_0000192)
SubClassOf(obo:CL_1001068 obo:CL_1000893)

# Class: obo:CL_1001096 (kidney afferent arteriole endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16990493") Annotation(oboInOwl:hasDbXref "PMID:22733355") Annotation(oboInOwl:hasDbXref "PMID:24066938") Annotation(oboInOwl:hasDbXref "PMID:25834230") obo:IAO_0000115 obo:CL_1001096 "An endothelial cell that lines the interior surface of the afferent arteriole and maintains vascular tone. This cell responds to changing ion concentrations and blood pressure by releasing vasoactive substances, in order to regulate blood flow into the glomeruli, which is essential for glomerular filtration.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001096 "KUPO:0001039")
AnnotationAssertion(rdfs:label obo:CL_1001096 "kidney afferent arteriole endothelial cell")
EquivalentClasses(obo:CL_1001096 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004639)))
SubClassOf(obo:CL_1001096 obo:CL_1001006)

# Class: obo:CL_1001097 (kidney afferent arteriole smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16990493") Annotation(oboInOwl:hasDbXref "PMID:22733355") Annotation(oboInOwl:hasDbXref "PMID:24066938") Annotation(oboInOwl:hasDbXref "PMID:25834230") obo:IAO_0000115 obo:CL_1001097 "A smooth muscle cell found in the wall of the afferent arteriole. This cell contracts and relaxes in response to changes in blood pressure, a process known as a myogenic response, to alter artery diameter and regulate blood flow into the glomeruli.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001097 "KUPO:0001040")
AnnotationAssertion(rdfs:label obo:CL_1001097 "kidney afferent arteriole smooth muscle cell")
EquivalentClasses(obo:CL_1001097 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004639)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001097 obo:CL_0000359)
SubClassOf(obo:CL_1001097 obo:CL_1001006)
SubClassOf(obo:CL_1001097 obo:CL_1001066)

# Class: obo:CL_1001099 (kidney efferent arteriole endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001099 "KUPO:0001042")
AnnotationAssertion(rdfs:label obo:CL_1001099 "kidney efferent arteriole endothelial cell")
EquivalentClasses(obo:CL_1001099 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004640)))

# Class: obo:CL_1001100 (kidney efferent arteriole smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001100 "KUPO:0001043")
AnnotationAssertion(rdfs:label obo:CL_1001100 "kidney efferent arteriole smooth muscle cell")
EquivalentClasses(obo:CL_1001100 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004640)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001100 obo:CL_0000359)
SubClassOf(obo:CL_1001100 obo:CL_1001009)
SubClassOf(obo:CL_1001100 obo:CL_1001066)

# Class: obo:CL_1001106 (kidney loop of Henle thick ascending limb epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25318757") obo:IAO_0000115 obo:CL_1001106 "An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001106 "KUPO:0001049")
AnnotationAssertion(rdfs:label obo:CL_1001106 "kidney loop of Henle thick ascending limb epithelial cell")
EquivalentClasses(obo:CL_1001106 ObjectIntersectionOf(obo:CL_1001016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001291)))
SubClassOf(obo:CL_1001106 obo:CL_1000504)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001106 obo:CL_1000615)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001106 obo:CL_1001016)
SubClassOf(obo:CL_1001106 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001291))

# Class: obo:CL_1001107 (kidney loop of Henle thin ascending limb epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001107 "An epithelial cell that is part of some loop of Henle thin ascending limb.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001107 "KUPO:0001050")
AnnotationAssertion(rdfs:label obo:CL_1001107 "kidney loop of Henle thin ascending limb epithelial cell")
EquivalentClasses(obo:CL_1001107 ObjectIntersectionOf(obo:CL_1001016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004193)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001107 obo:CL_1001016)
SubClassOf(obo:CL_1001107 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004193))

# Class: obo:CL_1001108 (kidney loop of Henle medullary thick ascending limb epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001108 "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001108 "KUPO:0001051")
AnnotationAssertion(rdfs:label obo:CL_1001108 "kidney loop of Henle medullary thick ascending limb epithelial cell")
EquivalentClasses(obo:CL_1001108 ObjectIntersectionOf(obo:CL_1001016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006376)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001108 obo:CL_1000616)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001108 obo:CL_1001016)
SubClassOf(obo:CL_1001108 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006376))

# Class: obo:CL_1001109 (kidney loop of Henle cortical thick ascending limb epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001109 "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001109 "KUPO:0001052")
AnnotationAssertion(rdfs:label obo:CL_1001109 "kidney loop of Henle cortical thick ascending limb epithelial cell")
EquivalentClasses(obo:CL_1001109 ObjectIntersectionOf(obo:CL_1001016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006854)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001109 obo:CL_1000615)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001109 obo:CL_1001016)
SubClassOf(obo:CL_1001109 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006854))

# Class: obo:CL_1001111 (kidney loop of Henle thin descending limb epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001111 "An epithelial cell that is part of some loop of Henle thin descending limb.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001111 "KUPO:0001054")
AnnotationAssertion(rdfs:label obo:CL_1001111 "kidney loop of Henle thin descending limb epithelial cell")
EquivalentClasses(obo:CL_1001111 ObjectIntersectionOf(obo:CL_1001021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005096)))
SubClassOf(obo:CL_1001111 obo:CL_1000616)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001111 obo:CL_1001021)
SubClassOf(obo:CL_1001111 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005096))

# Class: obo:CL_1001123 (kidney outer medulla peritubular capillary cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001123 "An endothelial cell that is part of the peritubular capillary of the outer renal medulla.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001123 "KUPO:0001066")
AnnotationAssertion(rdfs:label obo:CL_1001123 "kidney outer medulla peritubular capillary cell")
EquivalentClasses(obo:CL_1001123 ObjectIntersectionOf(obo:CL_1001033 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006341)))

# Class: obo:CL_1001124 (kidney cortex peritubular capillary cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001124 "An endothelial cell that is part of the peritubular capillary of the renal cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001124 "KUPO:0001067")
AnnotationAssertion(rdfs:label obo:CL_1001124 "kidney cortex peritubular capillary cell")
EquivalentClasses(obo:CL_1001124 ObjectIntersectionOf(obo:CL_1001033 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006851)))

# Class: obo:CL_1001126 (inner renal medulla vasa recta cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001126 "KUPO:0001069")
AnnotationAssertion(rdfs:label obo:CL_1001126 "inner renal medulla vasa recta cell")
EquivalentClasses(obo:CL_1001126 ObjectIntersectionOf(obo:CL_1001036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004776)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001126 obo:CL_1000617)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001126 obo:CL_1001036)
SubClassOf(obo:CL_1001126 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004776))

# Class: obo:CL_1001127 (outer renal medulla vasa recta cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001127 "KUPO:0001070")
AnnotationAssertion(rdfs:label obo:CL_1001127 "outer renal medulla vasa recta cell")
EquivalentClasses(obo:CL_1001127 ObjectIntersectionOf(obo:CL_1001036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004775)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001127 obo:CL_1000616)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001127 obo:CL_1001036)
SubClassOf(obo:CL_1001127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004775))

# Class: obo:CL_1001131 (vasa recta ascending limb cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001131 "A cell that is part of some vasa recta ascending limb.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001131 "KUPO:0001074")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20392798") Annotation(oboInOwl:hasDbXref "PMID:20392799") Annotation(oboInOwl:hasDbXref "PMID:26062876") rdfs:comment obo:CL_1001131 "It is known in some mammalian species that this cell may express PV-1, a component of the fenestral diaphragm.")
AnnotationAssertion(rdfs:label obo:CL_1001131 "vasa recta ascending limb cell")
EquivalentClasses(obo:CL_1001131 ObjectIntersectionOf(obo:CL_1001036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009091)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001131 obo:CL_1001036)
SubClassOf(obo:CL_1001131 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009091))

# Class: obo:CL_1001135 (arcuate artery cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001135 "KUPO:0001078")
AnnotationAssertion(rdfs:label obo:CL_1001135 "arcuate artery cell")
EquivalentClasses(obo:CL_1001135 ObjectIntersectionOf(obo:CL_1001045 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001552)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001135 obo:CL_1001045)
SubClassOf(obo:CL_1001135 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001552))

# Class: obo:CL_1001138 (interlobular artery cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001138 "KUPO:0001081")
AnnotationAssertion(rdfs:label obo:CL_1001138 "interlobular artery cell")
EquivalentClasses(obo:CL_1001138 ObjectIntersectionOf(obo:CL_1001045 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004723)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001138 obo:CL_1001045)
SubClassOf(obo:CL_1001138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004723))

# Class: obo:CL_1001142 (arcuate vein cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001142 "KUPO:0001085")
AnnotationAssertion(rdfs:label obo:CL_1001142 "arcuate vein cell")
EquivalentClasses(obo:CL_1001142 ObjectIntersectionOf(obo:CL_1001052 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004719)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001142 obo:CL_1001052)
SubClassOf(obo:CL_1001142 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004719))

# Class: obo:CL_1001145 (interlobular vein cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001145 "KUPO:0001088")
AnnotationAssertion(rdfs:label obo:CL_1001145 "interlobular vein cell")
EquivalentClasses(obo:CL_1001145 ObjectIntersectionOf(obo:CL_1001052 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005168)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001145 obo:CL_1001052)
SubClassOf(obo:CL_1001145 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005168))

# Class: obo:CL_1001209 (inner medulla vasa recta ascending limb cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001209 "KUPO:0001075")
AnnotationAssertion(rdfs:label obo:CL_1001209 "inner medulla vasa recta ascending limb cell")
EquivalentClasses(obo:CL_1001209 ObjectIntersectionOf(obo:CL_1001131 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009092)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001209 obo:CL_1001126)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001209 obo:CL_1001131)
SubClassOf(obo:CL_1001209 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009092))

# Class: obo:CL_1001210 (outer medulla vasa recta ascending limb cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001210 "KUPO:0001076")
AnnotationAssertion(rdfs:label obo:CL_1001210 "outer medulla vasa recta ascending limb cell")
EquivalentClasses(obo:CL_1001210 ObjectIntersectionOf(obo:CL_1001131 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009093)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001210 obo:CL_1001127)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001210 obo:CL_1001131)
SubClassOf(obo:CL_1001210 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009093))

# Class: obo:CL_1001213 (arcuate artery endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001213 "KUPO:0001079")
AnnotationAssertion(rdfs:label obo:CL_1001213 "arcuate artery endothelial cell")
EquivalentClasses(obo:CL_1001213 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001552)))
SubClassOf(obo:CL_1001213 obo:CL_1001135)

# Class: obo:CL_1001214 (arcuate artery smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001214 "KUPO:0001080")
AnnotationAssertion(rdfs:label obo:CL_1001214 "arcuate artery smooth muscle cell")
EquivalentClasses(obo:CL_1001214 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001552)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001214 obo:CL_0000359)
SubClassOf(obo:CL_1001214 obo:CL_1001064)
SubClassOf(obo:CL_1001214 obo:CL_1001135)

# Class: obo:CL_1001216 (interlobulary artery endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001216 "KUPO:0001082")
AnnotationAssertion(rdfs:label obo:CL_1001216 "interlobulary artery endothelial cell")
EquivalentClasses(obo:CL_1001216 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004723)))
SubClassOf(obo:CL_1001216 obo:CL_1001138)

# Class: obo:CL_1001217 (interlobulary artery smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001217 "KUPO:0001083")
AnnotationAssertion(rdfs:label obo:CL_1001217 "interlobulary artery smooth muscle cell")
EquivalentClasses(obo:CL_1001217 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004723)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001217 obo:CL_0000359)
SubClassOf(obo:CL_1001217 obo:CL_1001064)
SubClassOf(obo:CL_1001217 obo:CL_1001138)

# Class: obo:CL_1001220 (arcuate vein endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001220 "KUPO:0001086")
AnnotationAssertion(rdfs:label obo:CL_1001220 "arcuate vein endothelial cell")
EquivalentClasses(obo:CL_1001220 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004719)))
SubClassOf(obo:CL_1001220 obo:CL_1001142)

# Class: obo:CL_1001221 (arcuate vein smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001221 "KUPO:0001087")
AnnotationAssertion(rdfs:label obo:CL_1001221 "arcuate vein smooth muscle cell")
EquivalentClasses(obo:CL_1001221 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004719)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001221 obo:CL_0000359)
SubClassOf(obo:CL_1001221 obo:CL_1001068)
SubClassOf(obo:CL_1001221 obo:CL_1001142)

# Class: obo:CL_1001223 (interlobulary vein endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001223 "KUPO:0001089")
AnnotationAssertion(rdfs:label obo:CL_1001223 "interlobulary vein endothelial cell")
EquivalentClasses(obo:CL_1001223 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005168)))
SubClassOf(obo:CL_1001223 obo:CL_1001145)

# Class: obo:CL_1001224 (interlobulary vein smooth muscle cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001224 "KUPO:0001090")
AnnotationAssertion(rdfs:label obo:CL_1001224 "interlobulary vein smooth muscle cell")
EquivalentClasses(obo:CL_1001224 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005168)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001224 obo:CL_0000359)
SubClassOf(obo:CL_1001224 obo:CL_1001068)
SubClassOf(obo:CL_1001224 obo:CL_1001145)

# Class: obo:CL_1001225 (kidney collecting duct cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001225 "A cell that is part of a collecting duct of renal tubule.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001225 "KUPO:0001012")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001225 "Wikipedia:Kidney_collecting_duct_cell")
AnnotationAssertion(rdfs:label obo:CL_1001225 "kidney collecting duct cell")
EquivalentClasses(obo:CL_1001225 ObjectIntersectionOf(obo:CL_1000497 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232)))

# Class: obo:CL_1001285 (vasa recta descending limb cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001285 "A cell that is part of some vasa recta descending limb.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001285 "KUPO:0001071")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20392798") Annotation(oboInOwl:hasDbXref "PMID:20392799") Annotation(oboInOwl:hasDbXref "PMID:26062876") rdfs:comment obo:CL_1001285 "It is known in some mammalian species that this cell may express the urea transporter B.")
AnnotationAssertion(rdfs:label obo:CL_1001285 "vasa recta descending limb cell")
EquivalentClasses(obo:CL_1001285 ObjectIntersectionOf(obo:CL_1001036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009202)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001285 obo:CL_1001036)
SubClassOf(obo:CL_1001285 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009202))

# Class: obo:CL_1001286 (inner medulla vasa recta descending limb cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001286 "KUPO:0001072")
AnnotationAssertion(rdfs:label obo:CL_1001286 "inner medulla vasa recta descending limb cell")
EquivalentClasses(obo:CL_1001286 ObjectIntersectionOf(obo:CL_1001285 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009089)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001286 obo:CL_1001126)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001286 obo:CL_1001285)
SubClassOf(obo:CL_1001286 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009089))

# Class: obo:CL_1001287 (outer medulla vasa recta descending limb cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001287 "KUPO:0001073")
AnnotationAssertion(rdfs:label obo:CL_1001287 "outer medulla vasa recta descending limb cell")
EquivalentClasses(obo:CL_1001287 ObjectIntersectionOf(obo:CL_1001285 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009090)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001287 obo:CL_1001127)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001287 obo:CL_1001285)
SubClassOf(obo:CL_1001287 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009090))

# Class: obo:CL_1001318 (renal interstitial pericyte)

AnnotationAssertion(obo:IAO_0000115 obo:CL_1001318 "A pericyte cell located in the kidney interstitium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001318 "KUPO:0001104")
AnnotationAssertion(rdfs:label obo:CL_1001318 "renal interstitial pericyte")
EquivalentClasses(obo:CL_1001318 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005215)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001318 obo:CL_0000669)

# Class: obo:CL_1001319 (bladder cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001319 "KUPO:0001120")
AnnotationAssertion(rdfs:label obo:CL_1001319 "bladder cell")
EquivalentClasses(obo:CL_1001319 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001255)))
SubClassOf(obo:CL_1001319 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001255))

# Class: obo:CL_1001320 (urethra cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001320 "KUPO:0001123")
AnnotationAssertion(rdfs:label obo:CL_1001320 "urethra cell")
EquivalentClasses(obo:CL_1001320 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000057)))
SubClassOf(obo:CL_1001320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000057))

# Class: obo:CL_1001428 (bladder urothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") obo:IAO_0000115 obo:CL_1001428 "A urothelial cell that is part of the urothelium of the urinary bladder.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001428 "KUPO:0001121")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001428 "NCIT:C32210")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_1001428 "bladder transitional cell")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_1001428 "transitional epithelial cell of urinary bladder")
AnnotationAssertion(rdfs:label obo:CL_1001428 "bladder urothelial cell")
EquivalentClasses(obo:CL_1001428 ObjectIntersectionOf(obo:CL_0000731 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004645)))

# Class: obo:CL_1001430 (urethra urothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23589830") Annotation(oboInOwl:hasDbXref "PMID:36180582") obo:IAO_0000115 obo:CL_1001430 "A urothelial cell that is part of the urethra urothelium. This cell plays a crucial role in maintaining the urethral barrier function, protecting against toxic substances in urine, sensing environmental changes, and defending against pathogen entry.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001430 "KUPO:0001124")
AnnotationAssertion(rdfs:label obo:CL_1001430 "urethra urothelial cell")
EquivalentClasses(obo:CL_1001430 ObjectIntersectionOf(obo:CL_0000731 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004787)))

# Class: obo:CL_1001431 (kidney collecting duct principal cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001431 "KUPO:0001128")
AnnotationAssertion(rdfs:label obo:CL_1001431 "kidney collecting duct principal cell")
EquivalentClasses(obo:CL_1001431 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001431 obo:CL_0005009)
SubClassOf(obo:CL_1001431 obo:CL_1000454)
SubClassOf(obo:CL_1001431 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232))

# Class: obo:CL_1001432 (kidney collecting duct intercalated cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001432 "KUPO:0001129")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001432 "http://en.wikipedia.org/wiki/Collecting_duct_system#Intercalated_cells")
AnnotationAssertion(rdfs:label obo:CL_1001432 "kidney collecting duct intercalated cell")
EquivalentClasses(obo:CL_1001432 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1001432 obo:CL_0005010)
SubClassOf(obo:CL_1001432 obo:CL_1000454)
SubClassOf(obo:CL_1001432 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232))

# Class: obo:CL_1001433 (epithelial cell of exocrine pancreas)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_1001433 "An epithelial cell of the exocrine pancreas.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001433 "FMA:70986")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1001433 "exocrine pancreas cell")
AnnotationAssertion(rdfs:label obo:CL_1001433 "epithelial cell of exocrine pancreas")
EquivalentClasses(obo:CL_1001433 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000017)))

# Class: obo:CL_1001434 (olfactory bulb interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18603310") obo:IAO_0000115 obo:CL_1001434 "A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons")
AnnotationAssertion(rdfs:label obo:CL_1001434 "olfactory bulb interneuron")
EquivalentClasses(obo:CL_1001434 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002264)))
SubClassOf(obo:CL_1001434 obo:CL_0000101)
SubClassOf(obo:CL_1001434 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002264))

# Class: obo:CL_1001435 (periglomerular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0009943") obo:IAO_0000115 obo:CL_1001435 "The small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001435 "BTO:0003796")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001435 "NIFEXT:122")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFEXT:122") oboInOwl:hasExactSynonym obo:CL_1001435 "glomerular layer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFEXT:122") oboInOwl:hasExactSynonym obo:CL_1001435 "olfactory bulb (accessory) glomerular layer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFEXT:122") oboInOwl:hasExactSynonym obo:CL_1001435 "olfactory bulb glomerular layer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0009943") oboInOwl:hasExactSynonym obo:CL_1001435 "olfactory bulb glomerularal cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1001435 "olfactory bulb periglomerular cell")
AnnotationAssertion(rdfs:label obo:CL_1001435 "periglomerular cell")
SubClassOf(obo:CL_1001435 obo:CL_1001434)
SubClassOf(obo:CL_1001435 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005377))

# Class: obo:CL_1001436 (hair-tylotrich neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0000977") obo:IAO_0000115 obo:CL_1001436 "The subcutaneous mechanoreceptors that innervate tylotrich hair follicles.")
AnnotationAssertion(rdfs:label obo:CL_1001436 "hair-tylotrich neuron")
SubClassOf(obo:CL_1001436 obo:CL_0002487)

# Class: obo:CL_1001437 (hair-down neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0000979") obo:IAO_0000115 obo:CL_1001437 "The subcutaneous mechanoreceptors that innervate vellus hairs.")
AnnotationAssertion(rdfs:label obo:CL_1001437 "hair-down neuron")
SubClassOf(obo:CL_1001437 obo:CL_0002487)

# Class: obo:CL_1001451 (sensory neuron of dorsal root ganglion)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004297") obo:IAO_0000115 obo:CL_1001451 "A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0004297") oboInOwl:hasExactSynonym obo:CL_1001451 "proprioceptive neuron")
AnnotationAssertion(rdfs:label obo:CL_1001451 "sensory neuron of dorsal root ganglion")
EquivalentClasses(obo:CL_1001451 ObjectIntersectionOf(obo:CL_0000101 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000044)))
SubClassOf(obo:CL_1001451 obo:CL_4023168)
SubClassOf(obo:CL_1001451 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000044))

# Class: obo:CL_1001474 (medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0008462") Annotation(oboInOwl:hasDbXref "doi:10.1073/pnas.242428599") obo:IAO_0000115 obo:CL_1001474 "An inhibitory, GABAergic projection neuron in the striatum that integrates glutamatergic signals arising from the cerebral cortex and thalamus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001474 "BTO:0004778")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1073/pnas.242428599") oboInOwl:hasExactSynonym obo:CL_1001474 "gamma-aminobutyric acid (GABA)ergic spiny projection neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1073/pnas.242428599") oboInOwl:hasExactSynonym obo:CL_1001474 "gamma-aminobutyric acid ergic spiny projection neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0021773") oboInOwl:hasExactSynonym obo:CL_1001474 "striatal medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0004778") oboInOwl:hasRelatedSynonym obo:CL_1001474 "medium-sized densely spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41420-022-01088-0") Annotation(oboInOwl:hasDbXref "doi:10.1523/JNEUROSCI.20-16-06063.2000") rdfs:comment obo:CL_1001474 "Direct genetic lineage tracing in mice, including Dlx-based and Sp9-Cre fate mapping, demonstrates that medium spiny neurons (MSNs) originate from progenitors in the lateral ganglionic eminence (LGE), with labeled cells migrating from LGE to the striatum and expressing MSN markers such as FOXP1 and CTIP2.")
AnnotationAssertion(rdfs:label obo:CL_1001474 "medium spiny neuron")
SubClassOf(obo:CL_1001474 obo:CL_0000540)
SubClassOf(obo:CL_1001474 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000369))
SubClassOf(obo:CL_1001474 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004025))
SubClassOf(obo:CL_1001474 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_1001502 (mitral cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0009954") obo:IAO_0000115 obo:CL_1001502 "The large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex.")
AnnotationAssertion(rdfs:label obo:CL_1001502 "mitral cell")
SubClassOf(obo:CL_1001502 obo:CL_1001434)
SubClassOf(obo:CL_1001502 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0004186))

# Class: obo:CL_1001503 (olfactory bulb tufted cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0009955") obo:IAO_0000115 obo:CL_1001503 "The principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala.")
AnnotationAssertion(rdfs:label obo:CL_1001503 "olfactory bulb tufted cell")
SubClassOf(obo:CL_1001503 obo:CL_0000540)
SubClassOf(obo:CL_1001503 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005376))

# Class: obo:CL_1001505 (parvocellular neurosecretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0010125") obo:IAO_0000115 obo:CL_1001505 "The secretory neurons of the paraventricular nucleus that synthesize and secrete vasopressin, corticotropin-releasing factor (CRF) and thyrotropin-releasing hormone (TRH) into blood vessels in the hypothalamo-pituitary portal system.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1001505 "parvocellular neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1001505 "parvocellular neurosecretory neuron")
AnnotationAssertion(rdfs:label obo:CL_1001505 "parvocellular neurosecretory cell")
SubClassOf(obo:CL_1001505 obo:CL_0000540)
SubClassOf(obo:CL_1001505 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001930))
SubClassOf(obo:CL_1001505 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030103))

# Class: obo:CL_1001509 (glycinergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0010385") obo:IAO_0000115 obo:CL_1001509 "The neurons that utilize glycine as a neurotransmitter.")
AnnotationAssertion(rdfs:label obo:CL_1001509 "glycinergic neuron")
EquivalentClasses(obo:CL_1001509 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537)))
SubClassOf(obo:CL_1001509 obo:CL_0000540)

# Class: obo:CL_1001516 (intestinal enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0010802") obo:IAO_0000115 obo:CL_1001516 "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract.")
AnnotationAssertion(rdfs:label obo:CL_1001516 "intestinal enteroendocrine cell")
EquivalentClasses(obo:CL_1001516 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)))
SubClassOf(obo:CL_1001516 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))
SubClassOf(obo:CL_1001516 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4052006))

# Class: obo:CL_1001517 (stomach enteroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0010803") obo:IAO_0000115 obo:CL_1001517 "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach.")
AnnotationAssertion(rdfs:label obo:CL_1001517 "stomach enteroendocrine cell")
EquivalentClasses(obo:CL_1001517 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000945)))
SubClassOf(obo:CL_1001517 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))

# Class: obo:CL_1001561 (vomeronasal sensory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0011679") obo:IAO_0000115 obo:CL_1001561 "Chemosensitive cells that innervate the vomernasal organ epithelium and are responsible for receiving and transmitting pheromone signals.")
AnnotationAssertion(rdfs:label obo:CL_1001561 "vomeronasal sensory neuron")
EquivalentClasses(obo:CL_1001561 ObjectIntersectionOf(obo:CL_0000101 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002255) ObjectSomeValuesFrom(obo:RO_0013007 obo:UBERON_0003367)))

# Class: obo:CL_1001566 (obsolete bronchioalveolar stem cells)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MP:0011691") obo:IAO_0000115 obo:CL_1001566 "OBSOLETE. A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and club cells in response to lung injury.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_1001566 <https://github.com/obophenotype/cell-ontology/issues/1443>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_1001566 obo:CL_0002638)
AnnotationAssertion(rdfs:comment obo:CL_1001566 "Duplicated term - merged into CL:0002638")
AnnotationAssertion(rdfs:label obo:CL_1001566 "obsolete bronchioalveolar stem cells")
AnnotationAssertion(owl:deprecated obo:CL_1001566 "true"^^xsd:boolean)

# Class: obo:CL_1001567 (lung endothelial cell)

AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001567 "endothelial cell of lung")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001567 "pulmonary vessel endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1001567 "lung endothelial cell")
EquivalentClasses(obo:CL_1001567 ObjectIntersectionOf(obo:CL_0002139 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
SubClassOf(obo:CL_1001567 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000102))

# Class: obo:CL_1001568 (pulmonary artery endothelial cell)

AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001568 "BTO:0001141")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0001141") oboInOwl:hasRelatedSynonym obo:CL_1001568 "PAEC cell")
AnnotationAssertion(rdfs:label obo:CL_1001568 "pulmonary artery endothelial cell")
EquivalentClasses(obo:CL_1001568 ObjectIntersectionOf(obo:CL_0002139 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002012)))
SubClassOf(obo:CL_1001568 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005317))

# Class: obo:CL_1001569 (hippocampal interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") obo:IAO_0000115 obo:CL_1001569 "An interneuron with a soma found in the hippocampus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001569 "FMA:84777")
AnnotationAssertion(rdfs:label obo:CL_1001569 "hippocampal interneuron")
EquivalentClasses(obo:CL_1001569 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002421)))

# Class: obo:CL_1001571 (hippocampal pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") Annotation(oboInOwl:hasDbXref "PMID:19342486") obo:IAO_0000115 obo:CL_1001571 "A pyramidal neuron with a soma found in the hippocampus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001571 "NIFSTD:sao131261273")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001571 "SAO:sao131261273")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFSTD:sao131261273") oboInOwl:hasNarrowSynonym obo:CL_1001571 "hippocampus (CA) pyramidal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NIFSTD:sao131261273") oboInOwl:hasNarrowSynonym obo:CL_1001571 "hippocampus (CA) pyramidal neuron")
AnnotationAssertion(rdfs:label obo:CL_1001571 "hippocampal pyramidal neuron")
EquivalentClasses(obo:CL_1001571 ObjectIntersectionOf(obo:CL_0000598 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002421)))
SubClassOf(obo:CL_1001571 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002313))

# Class: obo:CL_1001572 (colon endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_1001572 "A vascular endothelial cell found in colon blood vessels.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001572 "CALOHA:TS-2397")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2397") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_1001572 "colon endothelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2397") oboInOwl:hasRelatedSynonym obo:CL_1001572 "colonic endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_1001572 "colon endothelial cell")
EquivalentClasses(obo:CL_1001572 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(obo:CL_1001572 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013695))

# Class: obo:CL_1001573 (nasopharyngeal epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001573 "Cell of the nasopharyngeal epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001573 "CALOHA:TS-2398")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2398") oboInOwl:hasRelatedSynonym obo:CL_1001573 "nasopharynx respiratory epithelial cells")
AnnotationAssertion(rdfs:label obo:CL_1001573 "nasopharyngeal epithelial cell")
EquivalentClasses(obo:CL_1001573 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001728)))
SubClassOf(obo:CL_1001573 obo:CL_0000066)
SubClassOf(obo:CL_1001573 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001951))

# Class: obo:CL_1001575 (uterine cervix squamous cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001575 "Squamous cell of uterine cervix epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001575 "CALOHA:TS-1251")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1251") oboInOwl:hasRelatedSynonym obo:CL_1001575 "cervix squamous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1251") oboInOwl:hasRelatedSynonym obo:CL_1001575 "cervix squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1251") oboInOwl:hasRelatedSynonym obo:CL_1001575 "cervix, uterine squamous epithelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1251") oboInOwl:hasRelatedSynonym obo:CL_1001575 "uterine cervix squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1251") oboInOwl:hasRelatedSynonym obo:CL_1001575 "uterine cervix squamous epithelial cells")
AnnotationAssertion(rdfs:label obo:CL_1001575 "uterine cervix squamous cell")
EquivalentClasses(obo:CL_1001575 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000002)))
SubClassOf(obo:CL_1001575 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004801))

# Class: obo:CL_1001576 (oral mucosa squamous cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001576 "Squamous cell of oral epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001576 "CALOHA:TS-1252")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1252") oboInOwl:hasRelatedSynonym obo:CL_1001576 "oral cavity mucosa squamous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1252") oboInOwl:hasRelatedSynonym obo:CL_1001576 "oral cavity mucosa squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1252") oboInOwl:hasRelatedSynonym obo:CL_1001576 "oral mucosa squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1252") oboInOwl:hasRelatedSynonym obo:CL_1001576 "oral mucosa squamous epithelial cells")
AnnotationAssertion(rdfs:label obo:CL_1001576 "oral mucosa squamous cell")
EquivalentClasses(obo:CL_1001576 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002424)))

# Class: obo:CL_1001577 (tonsil squamous cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001577 "Squamous cell of tonsil epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001577 "CALOHA:TS-1253")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1253") oboInOwl:hasRelatedSynonym obo:CL_1001577 "tonsil squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1253") oboInOwl:hasRelatedSynonym obo:CL_1001577 "tonsil squamous epithelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1253") oboInOwl:hasRelatedSynonym obo:CL_1001577 "tonsillar squamous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1253") oboInOwl:hasRelatedSynonym obo:CL_1001577 "tonsillar squamous epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_1001577 "tonsil squamous cell")
EquivalentClasses(obo:CL_1001577 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002372)))
SubClassOf(obo:CL_1001577 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013696))

# Class: obo:CL_1001578 (vagina squamous cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001578 "Squamous cell of vaginal epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001578 "CALOHA:TS-1254")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1254") oboInOwl:hasRelatedSynonym obo:CL_1001578 "vagina squamous epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1254") oboInOwl:hasRelatedSynonym obo:CL_1001578 "vagina squamous epithelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1254") oboInOwl:hasRelatedSynonym obo:CL_1001578 "vaginal squamous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1254") oboInOwl:hasRelatedSynonym obo:CL_1001578 "vaginal squamous epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_1001578 "vagina squamous cell")
EquivalentClasses(obo:CL_1001578 ObjectIntersectionOf(obo:CL_0000076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000996)))
SubClassOf(obo:CL_1001578 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001344))

# Class: obo:CL_1001579 (cerebral cortex glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001579 "Glial cell of cerebral cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001579 "CALOHA:TS-1256")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1256") oboInOwl:hasRelatedSynonym obo:CL_1001579 "brain cortex glial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1256") oboInOwl:hasRelatedSynonym obo:CL_1001579 "cerebral cortex glial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1256") oboInOwl:hasRelatedSynonym obo:CL_1001579 "cerebrum cortex glial cell")
AnnotationAssertion(rdfs:label obo:CL_1001579 "cerebral cortex glial cell")
EquivalentClasses(obo:CL_1001579 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000956)))

# Class: obo:CL_1001580 (hippocampal glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001580 "A glial cell that is part of the hippocampus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001580 "CALOHA:TS-1257")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1257") oboInOwl:hasExactSynonym obo:CL_1001580 "hippocampus glial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1257") oboInOwl:hasExactSynonym obo:CL_1001580 "hippocampus neuroglial cell")
AnnotationAssertion(rdfs:label obo:CL_1001580 "hippocampal glial cell")
EquivalentClasses(obo:CL_1001580 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002421)))

# Class: obo:CL_1001581 (lateral ventricle glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001581 "Glial cell of lateral ventricle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001581 "CALOHA:TS-1258")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1258") oboInOwl:hasRelatedSynonym obo:CL_1001581 "lateral ventricle glial cells")
AnnotationAssertion(rdfs:label obo:CL_1001581 "lateral ventricle glial cell")
EquivalentClasses(obo:CL_1001581 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002285)))

# Class: obo:CL_1001582 (lateral ventricle neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001582 "Neuron of lateral ventricle.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001582 "CALOHA:TS-1261")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1261") oboInOwl:hasRelatedSynonym obo:CL_1001582 "lateral ventricle neural cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1261") oboInOwl:hasRelatedSynonym obo:CL_1001582 "lateral ventricle neuronal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1261") oboInOwl:hasRelatedSynonym obo:CL_1001582 "lateral ventricle neuronal cells")
AnnotationAssertion(rdfs:label obo:CL_1001582 "lateral ventricle neuron")
EquivalentClasses(obo:CL_1001582 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002285)))

# Class: obo:CL_1001583 (obsolete breast adipocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:Breast") obo:IAO_0000115 obo:CL_1001583 "OBSOLETE: Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_1001583 obo:CL_0002617)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2377") oboInOwl:hasRelatedSynonym obo:CL_1001583 "breast adipocytes")
AnnotationAssertion(rdfs:label obo:CL_1001583 "obsolete breast adipocyte")
AnnotationAssertion(owl:deprecated obo:CL_1001583 "true"^^xsd:boolean)

# Class: obo:CL_1001585 (appendix glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001585 "Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001585 "CALOHA:TS-1271")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1271") oboInOwl:hasRelatedSynonym obo:CL_1001585 "appendix glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1271") oboInOwl:hasRelatedSynonym obo:CL_1001585 "caecal appendix glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1271") oboInOwl:hasRelatedSynonym obo:CL_1001585 "cecal appendix glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1271") oboInOwl:hasRelatedSynonym obo:CL_1001585 "vermiform appendix glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001585 "appendix glandular cell")
EquivalentClasses(obo:CL_1001585 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001154)))
SubClassOf(obo:CL_1001585 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009697))

# Class: obo:CL_1001586 (mammary gland glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001586 "Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001586 "CALOHA:TS-1272")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1272") oboInOwl:hasRelatedSynonym obo:CL_1001586 "breast glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1272") oboInOwl:hasRelatedSynonym obo:CL_1001586 "breast glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1272") oboInOwl:hasRelatedSynonym obo:CL_1001586 "mammary glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001586 "mammary gland glandular cell")
EquivalentClasses(obo:CL_1001586 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911)))
SubClassOf(obo:CL_1001586 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003244))

# Class: obo:CL_1001587 (uterine cervix secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001587 "Glandular cell of uterine cervix epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001587 "CALOHA:TS-1273")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix, uterine glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix, uterine glandular cells")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001587 "uterine cervix glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001587 "uterine cervix secretory cell")
EquivalentClasses(obo:CL_1001587 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000002)))
SubClassOf(obo:CL_1001587 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004801))

# Class: obo:CL_1001588 (colon glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001588 "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001588 "CALOHA:TS-1274")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1274") oboInOwl:hasRelatedSynonym obo:CL_1001588 "colon glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001588 "colon glandular cell")
EquivalentClasses(obo:CL_1001588 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(obo:CL_1001588 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397))

# Class: obo:CL_1001589 (duodenum secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001589 "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001589 "CALOHA:TS-1275")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1275") oboInOwl:hasNarrowSynonym obo:CL_1001589 "duodenum glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001589 "duodenum secretory cell")
EquivalentClasses(obo:CL_1001589 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114)))
SubClassOf(obo:CL_1001589 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))
SubClassOf(obo:CL_1001589 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346))

# Class: obo:CL_1001590 (epididymis secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001590 "Glandular cell of epididymal epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001590 "CALOHA:TS-1276")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1276") oboInOwl:hasRelatedSynonym obo:CL_1001590 "epididymal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1276") oboInOwl:hasRelatedSynonym obo:CL_1001590 "epididymis glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001590 "epididymis secretory cell")
EquivalentClasses(obo:CL_1001590 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001301)))
SubClassOf(obo:CL_1001590 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004544))

# Class: obo:CL_1001591 (oviduct secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001591 "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001591 "CALOHA:TS-1277")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cells")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001591 "oviduct glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "uterine tube glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001591 "oviduct secretory cell")
EquivalentClasses(obo:CL_1001591 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000993)))
SubClassOf(obo:CL_1001591 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004804))

# Class: obo:CL_1001592 (gallbladder glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001592 "Glandular cell of gallbladder epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001592 "CALOHA:TS-1278")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:7202") oboInOwl:hasExactSynonym obo:CL_1001592 "gall bladder glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1278") oboInOwl:hasRelatedSynonym obo:CL_1001592 "gall bladder glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1278") oboInOwl:hasRelatedSynonym obo:CL_1001592 "gallbladder glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001592 "gallbladder glandular cell")
EquivalentClasses(obo:CL_1001592 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002110)))
SubClassOf(obo:CL_1001592 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002029))

# Class: obo:CL_1001593 (parathyroid glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001593 "Glandular (secretory) cell of parathyroid epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001593 "CALOHA:TS-1279")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1279") oboInOwl:hasRelatedSynonym obo:CL_1001593 "parathyroid gland glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1279") oboInOwl:hasRelatedSynonym obo:CL_1001593 "parathyroid gland glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001593 "parathyroid glandular cell")
EquivalentClasses(obo:CL_1001593 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001132)))

# Class: obo:CL_1001595 (rectum glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001595 "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001595 "CALOHA:TS-1281")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1281") oboInOwl:hasRelatedSynonym obo:CL_1001595 "rectal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1281") oboInOwl:hasRelatedSynonym obo:CL_1001595 "rectum glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001595 "rectum glandular cell")
EquivalentClasses(obo:CL_1001595 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001052)))
SubClassOf(obo:CL_1001595 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003354))

# Class: obo:CL_1001596 (salivary gland glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001596 "Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001596 "CALOHA:TS-1282")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1282") oboInOwl:hasRelatedSynonym obo:CL_1001596 "salivary gland glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001596 "salivary gland glandular cell")
EquivalentClasses(obo:CL_1001596 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001044)))
SubClassOf(obo:CL_1001596 obo:CL_0009005)
SubClassOf(obo:CL_1001596 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004809))

# Class: obo:CL_1001597 (seminal vesicle glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001597 "Glandular cell of seminal vesicle epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001597 "CALOHA:TS-1283")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1283") oboInOwl:hasRelatedSynonym obo:CL_1001597 "seminal vesicle glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001597 "seminal vesicle glandular cell")
EquivalentClasses(obo:CL_1001597 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000998)))
SubClassOf(obo:CL_1001597 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004805))

# Class: obo:CL_1001598 (small intestine secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NCI_Thesaurus:Small_Intestinal_Glandular_Cell") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001598 "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) .")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001598 "CALOHA:TS-1286")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001598 "FMA:86928")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasNarrowSynonym obo:CL_1001598 "small intestinal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasRelatedSynonym obo:CL_1001598 "small bowel glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasRelatedSynonym obo:CL_1001598 "small intestine glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001598 "small intestine secretory cell")
EquivalentClasses(obo:CL_1001598 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(obo:CL_1001598 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1001599 (pancreas exocrine glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001599 "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001599 "BTO:0000028")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001599 "CALOHA:TS-1242")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1242") oboInOwl:hasRelatedSynonym obo:CL_1001599 "exocrine pancreas glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1242") oboInOwl:hasRelatedSynonym obo:CL_1001599 "pancreas exocrine glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001599 "pancreas exocrine glandular cell")
EquivalentClasses(obo:CL_1001599 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000017)))
SubClassOf(obo:CL_1001599 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013697))

# Class: obo:CL_1001601 (adrenal gland glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001601 "Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001601 "CALOHA:TS-2177")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2177") oboInOwl:hasRelatedSynonym obo:CL_1001601 "adrenal gland glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2177") oboInOwl:hasRelatedSynonym obo:CL_1001601 "adrenal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2177") oboInOwl:hasRelatedSynonym obo:CL_1001601 "suprarenal gland glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001601 "adrenal gland glandular cell")
EquivalentClasses(obo:CL_1001601 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001235)))

# Class: obo:CL_1001602 (cerebral cortex endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001602 "A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001602 "CALOHA:TS-2372")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2372") oboInOwl:hasRelatedSynonym obo:CL_1001602 "cerebral cortex endothelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2372") oboInOwl:hasRelatedSynonym obo:CL_1001602 "endothelial cells of cerebral cortex")
AnnotationAssertion(rdfs:label obo:CL_1001602 "cerebral cortex endothelial cell")
EquivalentClasses(obo:CL_1001602 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000956)))
SubClassOf(obo:CL_1001602 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013694))

# Class: obo:CL_1001603 (lung macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001603 "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001603 "CALOHA:TS-0576")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-0576") oboInOwl:hasRelatedSynonym obo:CL_1001603 "lung macrophages")
AnnotationAssertion(rdfs:label obo:CL_1001603 "lung macrophage")
EquivalentClasses(obo:CL_1001603 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))

# Class: obo:CL_1001606 (foreskin keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001606 "Keratinocyte from foreskin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001606 "CALOHA:TS-0385")
AnnotationAssertion(rdfs:label obo:CL_1001606 "foreskin keratinocyte")
EquivalentClasses(obo:CL_1001606 ObjectIntersectionOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001332)))

# Class: obo:CL_1001607 (articular chondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001607 "Chondrocyte forming the hyaline cartilage found in joints.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001607 "CALOHA:TS-0056")
AnnotationAssertion(rdfs:label obo:CL_1001607 "articular chondrocyte")
EquivalentClasses(obo:CL_1001607 ObjectIntersectionOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010996)))

# Class: obo:CL_1001608 (foreskin fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001608 "Fibroblast from foreskin.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001608 "CALOHA:TS-0384")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_1001608 "BJ fibroblast")
AnnotationAssertion(rdfs:label obo:CL_1001608 "foreskin fibroblast")
EquivalentClasses(obo:CL_1001608 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001332)))

# Class: obo:CL_1001609 (muscle fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001609 "Fibroblast from muscle organ.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001609 "CALOHA:TS-0643")
AnnotationAssertion(rdfs:label obo:CL_1001609 "muscle fibroblast")
EquivalentClasses(obo:CL_1001609 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001630)))

# Class: obo:CL_1001610 (bone marrow hematopoietic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001610 "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001610 "CALOHA:TS-2109")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2109") oboInOwl:hasRelatedSynonym obo:CL_1001610 "bone marrow hematopoietic cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2109") oboInOwl:hasRelatedSynonym obo:CL_1001610 "bone marrow poietic cells")
AnnotationAssertion(rdfs:label obo:CL_1001610 "bone marrow hematopoietic cell")
EquivalentClasses(obo:CL_1001610 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371)))
SubClassOf(obo:CL_1001610 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012429))

# Class: obo:CL_1001611 (cerebellar neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001611 "Neuron of the cerebellum.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001611 "CALOHA:TS-2359")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001611 "FMA:84665")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2359") oboInOwl:hasRelatedSynonym obo:CL_1001611 "cerebellum neuron")
AnnotationAssertion(rdfs:label obo:CL_1001611 "cerebellar neuron")
EquivalentClasses(obo:CL_1001611 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002037)))

# Class: obo:CL_1100001 (secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0002-7073-9172>) obo:IAO_0000115 obo:CL_1100001 "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules.")
AnnotationAssertion(terms:contributor obo:CL_1100001 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_1100001 "2024-07-21T09:24:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_1100001 "secretory epithelial cell"@en)
EquivalentClasses(obo:CL_1100001 ObjectIntersectionOf(obo:CL_0000066 obo:CL_0000151))

# Class: obo:CL_2000000 (epidermal melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000000 "Any melanocyte that is part of a epidermis.")
AnnotationAssertion(terms:contributor obo:CL_2000000 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000000 "2014-02-03T23:03:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000000 "CL:2000000")
AnnotationAssertion(rdfs:comment obo:CL_2000000 "These cells are found primarily, but not exclusively, in primates including humans")
AnnotationAssertion(rdfs:label obo:CL_2000000 "epidermal melanocyte")
EquivalentClasses(obo:CL_2000000 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003)))

# Class: obo:CL_2000001 (peripheral blood mononuclear cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000001 "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.")
AnnotationAssertion(terms:contributor obo:CL_2000001 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000001 "2014-02-11T17:29:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000001 "CL:2000001")
AnnotationAssertion(rdfs:label obo:CL_2000001 "peripheral blood mononuclear cell")
EquivalentClasses(obo:CL_2000001 ObjectIntersectionOf(obo:CL_0000842 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000178)))

# Class: obo:CL_2000002 (decidual cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0002770") Annotation(oboInOwl:hasDbXref "NCIT:C32429") Annotation(oboInOwl:hasDbXref "PMID:30013421") Annotation(oboInOwl:hasDbXref "PMID:30429548") Annotation(oboInOwl:hasDbXref "Wiki:Decidual_cells&oldid=937509751") Annotation(oboInOwl:hasDbXref "Wiki:Decidualization&oldid=908981933") obo:IAO_0000115 obo:CL_2000002 "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization.")
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000002 "2014-02-20T23:06:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000002 "BTO:0002770")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000002 "BTO:0005756")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000002 "NCIT:C32429")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0002770") Annotation(oboInOwl:hasDbXref "NCIT:C32429") oboInOwl:hasExactSynonym obo:CL_2000002 "decidua cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "BTO:0005756") Annotation(oboInOwl:hasDbXref "PMID:11719592") oboInOwl:hasExactSynonym obo:CL_2000002 "decidual stromal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31907034") oboInOwl:hasExactSynonym obo:CL_2000002 "decidualized endometrial stromal cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000002 "CL:2000002")
AnnotationAssertion(rdfs:label obo:CL_2000002 "decidual cell")
SubClassOf(obo:CL_2000002 obo:CL_0000499)
SubClassOf(obo:CL_2000002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002450))
SubClassOf(obo:CL_2000002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002255))

# Class: obo:CL_2000004 (pituitary gland cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000004 "Any cell that is part of a pituitary gland.")
AnnotationAssertion(terms:contributor obo:CL_2000004 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000004 "2014-03-26T22:14:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000004 "CL:2000004")
AnnotationAssertion(rdfs:label obo:CL_2000004 "pituitary gland cell")
EquivalentClasses(obo:CL_2000004 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000007)))

# Class: obo:CL_2000005 (brain macroglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000005 "Any macroglial cell that is part of a brain.")
AnnotationAssertion(terms:contributor obo:CL_2000005 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000005 "2014-03-28T21:35:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000005 "CL:2000005")
AnnotationAssertion(rdfs:label obo:CL_2000005 "brain macroglial cell")
EquivalentClasses(obo:CL_2000005 ObjectIntersectionOf(obo:CL_0000126 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000955)))

# Class: obo:CL_2000006 (tonsil germinal center B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000006 "Any germinal center B cell that is part of a tonsil.")
AnnotationAssertion(terms:contributor obo:CL_2000006 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000006 "2014-03-28T21:35:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000006 "CL:2000006")
AnnotationAssertion(rdfs:label obo:CL_2000006 "tonsil germinal center B cell")
EquivalentClasses(obo:CL_2000006 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002372)))

# Class: obo:CL_2000007 (articular chondrocyte of knee joint)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000007 "Chondrocyte forming the hyaline cartilage found in the knee joint.")
AnnotationAssertion(terms:contributor obo:CL_2000007 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000007 "2014-06-04T14:40:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000007 "CL:2000007")
AnnotationAssertion(rdfs:label obo:CL_2000007 "articular chondrocyte of knee joint")
EquivalentClasses(obo:CL_2000007 ObjectIntersectionOf(obo:CL_1001607 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001485)))

# Class: obo:CL_2000008 (microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000008 "Any blood vessel endothelial cell that is part of a microvascular endothelium.")
AnnotationAssertion(terms:contributor obo:CL_2000008 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000008 "2014-06-04T15:07:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000008 "CL:2000008")
AnnotationAssertion(rdfs:label obo:CL_2000008 "microvascular endothelial cell")
EquivalentClasses(obo:CL_2000008 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008339)))

# Class: obo:CL_2000009 (obsolete microvascular endothelium blood vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000009 "Any blood vessel endothelial cell that is part of a microvascular endothelium.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_2000009 obo:CL_2000008)
AnnotationAssertion(terms:contributor obo:CL_2000009 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000009 "2014-06-04T15:09:18Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000009 "CL:2000009")
AnnotationAssertion(rdfs:label obo:CL_2000009 "obsolete microvascular endothelium blood vessel endothelial cell")
AnnotationAssertion(owl:deprecated obo:CL_2000009 "true"^^xsd:boolean)

# Class: obo:CL_2000010 (dermis blood vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000010 "Any blood vessel endothelial cell that is part of a dermis.")
AnnotationAssertion(terms:contributor obo:CL_2000010 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000010 "2014-06-04T15:12:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000010 "CL:2000010")
AnnotationAssertion(rdfs:label obo:CL_2000010 "dermis blood vessel endothelial cell")
EquivalentClasses(obo:CL_2000010 ObjectIntersectionOf(obo:CL_0000071 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067)))

# Class: obo:CL_2000011 (dermis lymphatic vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000011 "Any endothelial cell of lymphatic vessel that is part of a dermis.")
AnnotationAssertion(terms:contributor obo:CL_2000011 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000011 "2014-06-04T15:15:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000011 "CL:2000011")
AnnotationAssertion(rdfs:label obo:CL_2000011 "dermis lymphatic vessel endothelial cell")
EquivalentClasses(obo:CL_2000011 ObjectIntersectionOf(obo:CL_0002138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067)))

# Class: obo:CL_2000012 (fibroblast of pedal digit skin)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000012 "Any skin fibroblast that is part of a pedal digit skin.")
AnnotationAssertion(terms:contributor obo:CL_2000012 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000012 "2014-06-04T15:16:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000012 "CL:2000012")
AnnotationAssertion(rdfs:label obo:CL_2000012 "fibroblast of pedal digit skin")
EquivalentClasses(obo:CL_2000012 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003530)))

# Class: obo:CL_2000013 (fibroblast of skin of abdomen)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000013 "Any skin fibroblast that is part of a skin of abdomen.")
AnnotationAssertion(terms:contributor obo:CL_2000013 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000013 "2014-06-04T15:18:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000013 "CL:2000013")
AnnotationAssertion(rdfs:label obo:CL_2000013 "fibroblast of skin of abdomen")
EquivalentClasses(obo:CL_2000013 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001416)))

# Class: obo:CL_2000014 (fibroblast of upper leg skin)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000014 "Any skin fibroblast that is part of a upper leg skin.")
AnnotationAssertion(terms:contributor obo:CL_2000014 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000014 "2014-06-04T15:19:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000014 "CL:2000014")
AnnotationAssertion(rdfs:label obo:CL_2000014 "fibroblast of upper leg skin")
EquivalentClasses(obo:CL_2000014 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004262)))

# Class: obo:CL_2000015 (fibroblast of arm)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000015 "Any skin fibroblast that is part of a arm.")
AnnotationAssertion(terms:contributor obo:CL_2000015 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000015 "2014-06-04T15:29:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000015 "CL:2000015")
AnnotationAssertion(rdfs:label obo:CL_2000015 "fibroblast of arm")
EquivalentClasses(obo:CL_2000015 ObjectIntersectionOf(obo:CL_0002620 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001460)))

# Class: obo:CL_2000016 (lung microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000016 "Any lung endothelial cell that is part of a microvascular endothelium.")
AnnotationAssertion(terms:contributor obo:CL_2000016 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000016 "2014-06-04T16:00:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000016 "CL:2000016")
AnnotationAssertion(rdfs:label obo:CL_2000016 "lung microvascular endothelial cell")
EquivalentClasses(obo:CL_2000016 ObjectIntersectionOf(obo:CL_1001567 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008339)))
SubClassOf(obo:CL_2000016 obo:CL_2000008)

# Class: obo:CL_2000017 (fibroblast of peridontal ligament)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000017 "Any fibroblast that is part of a periodontal ligament.")
AnnotationAssertion(terms:contributor obo:CL_2000017 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000017 "2014-06-04T16:50:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000017 "CL:2000017")
AnnotationAssertion(rdfs:label obo:CL_2000017 "fibroblast of peridontal ligament")
EquivalentClasses(obo:CL_2000017 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008266)))

# Class: obo:CL_2000018 (endothelial cell of coronary artery)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000018 "Any endothelial cell of artery that is part of a coronary artery.")
AnnotationAssertion(terms:contributor obo:CL_2000018 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000018 "2014-06-04T17:08:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000018 "CL:2000018")
AnnotationAssertion(rdfs:label obo:CL_2000018 "endothelial cell of coronary artery")
EquivalentClasses(obo:CL_2000018 ObjectIntersectionOf(obo:CL_1000413 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001621)))

# Class: obo:CL_2000019 (compound eye photoreceptor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000019 "Any photoreceptor cell that is part of a compound eye.")
AnnotationAssertion(terms:contributor obo:CL_2000019 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000019 "2014-06-24T23:16:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000019 "CL:2000019")
AnnotationAssertion(rdfs:label obo:CL_2000019 "compound eye photoreceptor cell")
EquivalentClasses(obo:CL_2000019 ObjectIntersectionOf(obo:CL_0000210 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000018)))

# Class: obo:CL_2000020 (inner cell mass cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000020 "Any native cell that is part of a inner cell mass.")
AnnotationAssertion(terms:contributor obo:CL_2000020 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000020 "2014-06-24T23:16:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000020 "CL:2000020")
AnnotationAssertion(rdfs:label obo:CL_2000020 "inner cell mass cell")
EquivalentClasses(obo:CL_2000020 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000087)))

# Class: obo:CL_2000021 (sebaceous gland cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000021 "Any native cell that is part of a sebaceous gland.")
AnnotationAssertion(terms:contributor obo:CL_2000021 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000021 "2014-06-24T23:17:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000021 "CL:2000021")
AnnotationAssertion(rdfs:label obo:CL_2000021 "sebaceous gland cell")
EquivalentClasses(obo:CL_2000021 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001821)))

# Class: obo:CL_2000022 (cardiac septum cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000022 "Any native cell that is part of a cardiac septum.")
AnnotationAssertion(terms:contributor obo:CL_2000022 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000022 "2014-06-24T23:17:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000022 "CL:2000022")
AnnotationAssertion(rdfs:label obo:CL_2000022 "cardiac septum cell")
EquivalentClasses(obo:CL_2000022 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002099)))

# Class: obo:CL_2000023 (spinal cord ventral column interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000023 "Any interneuron that is part of a spinal cord ventral column.")
AnnotationAssertion(terms:contributor obo:CL_2000023 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000023 "2014-06-25T00:23:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000023 "CL:2000023")
AnnotationAssertion(rdfs:label obo:CL_2000023 "spinal cord ventral column interneuron")
EquivalentClasses(obo:CL_2000023 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005375)))

# Class: obo:CL_2000024 (spinal cord medial motor column neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000024 "Any neuron that is part of a spinal cord medial motor column.")
AnnotationAssertion(terms:contributor obo:CL_2000024 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000024 "2014-06-25T00:23:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000024 "CL:2000024")
AnnotationAssertion(rdfs:label obo:CL_2000024 "spinal cord medial motor column neuron")
EquivalentClasses(obo:CL_2000024 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0004059)))

# Class: obo:CL_2000025 (spinal cord oligodendrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000025 "Any oligodendrocyte that is part of a spinal cord.")
AnnotationAssertion(terms:contributor obo:CL_2000025 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000025 "2014-06-25T00:23:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000025 "CL:2000025")
AnnotationAssertion(rdfs:label obo:CL_2000025 "spinal cord oligodendrocyte")
EquivalentClasses(obo:CL_2000025 ObjectIntersectionOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002240)))

# Class: obo:CL_2000026 (obsolete cerebellum Golgi cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000026 "Any Golgi cell that is part of a cerebellum.")
AnnotationAssertion(terms:contributor obo:CL_2000026 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000026 "2014-06-25T00:23:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000026 "CL:2000026")
AnnotationAssertion(rdfs:label obo:CL_2000026 "obsolete cerebellum Golgi cell")
AnnotationAssertion(owl:deprecated obo:CL_2000026 "true"^^xsd:boolean)

# Class: obo:CL_2000027 (cerebellar basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32990595") Annotation(oboInOwl:hasDbXref "PMID:8915580") obo:IAO_0000115 obo:CL_2000027 "A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions.")
AnnotationAssertion(terms:contributor obo:CL_2000027 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000027 "2014-06-25T00:24:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000027 "cerebellum basket cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000027 "CL:2000027")
AnnotationAssertion(rdfs:label obo:CL_2000027 "cerebellar basket cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_2000027 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_2000027 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.png>)
EquivalentClasses(obo:CL_2000027 ObjectIntersectionOf(obo:CL_0000118 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002037)))
SubClassOf(obo:CL_2000027 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002974))

# Class: obo:CL_2000028 (cerebellum glutamatergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000028 "Any glutamatergic neuron that is part of a cerebellum.")
AnnotationAssertion(terms:contributor obo:CL_2000028 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000028 "2014-06-25T00:24:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000028 "CL:2000028")
AnnotationAssertion(rdfs:label obo:CL_2000028 "cerebellum glutamatergic neuron")
EquivalentClasses(obo:CL_2000028 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002037)))

# Class: obo:CL_2000029 (central nervous system neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000029 "Any neuron that is part of a central nervous system.")
AnnotationAssertion(terms:contributor obo:CL_2000029 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000029 "2014-06-25T01:17:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000029 "CL:2000029")
AnnotationAssertion(rdfs:label obo:CL_2000029 "central nervous system neuron")
EquivalentClasses(obo:CL_2000029 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017)))

# Class: obo:CL_2000030 (hypothalamus cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000030 "Any native cell that is part of a hypothalamus.")
AnnotationAssertion(terms:contributor obo:CL_2000030 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000030 "2014-06-25T01:17:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000030 "CL:2000030")
AnnotationAssertion(rdfs:label obo:CL_2000030 "hypothalamus cell")
EquivalentClasses(obo:CL_2000030 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001898)))

# Class: obo:CL_2000031 (lateral line ganglion neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000031 "Any neuron that is part of a lateral line ganglion.")
AnnotationAssertion(terms:contributor obo:CL_2000031 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000031 "2014-06-25T01:17:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000031 "CL:2000031")
AnnotationAssertion(rdfs:label obo:CL_2000031 "lateral line ganglion neuron")
EquivalentClasses(obo:CL_2000031 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_2000120)))
SubClassOf(obo:CL_2000031 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_32443))

# Class: obo:CL_2000032 (peripheral nervous system neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_2000032 "A neuron that is part of a peripheral nervous system.")
AnnotationAssertion(terms:contributor obo:CL_2000032 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000032 "2014-06-25T02:28:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000032 "FMA:84664")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000032 "PNS neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000032 "peripheral neuron")
AnnotationAssertion(oboInOwl:id obo:CL_2000032 "CL:2000032")
AnnotationAssertion(rdfs:label obo:CL_2000032 "peripheral nervous system neuron")
EquivalentClasses(obo:CL_2000032 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000010)))

# Class: obo:CL_2000033 (limb basal cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000033 "Any basal cell of epidermis that is part of a limb.")
AnnotationAssertion(terms:contributor obo:CL_2000033 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000033 "2014-06-25T02:28:25Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000033 "CL:2000033")
AnnotationAssertion(rdfs:label obo:CL_2000033 "limb basal cell of epidermis")
EquivalentClasses(obo:CL_2000033 ObjectIntersectionOf(obo:CL_0002187 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002101)))

# Class: obo:CL_2000034 (anterior lateral line neuromast hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000034 "Any neuromast hair cell that is part of a anterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000034 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000034 "2014-06-25T03:44:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000034 "CL:2000034")
AnnotationAssertion(rdfs:label obo:CL_2000034 "anterior lateral line neuromast hair cell")
EquivalentClasses(obo:CL_2000034 ObjectIntersectionOf(obo:CL_0000856 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_2001470)))

# Class: obo:CL_2000035 (anterior lateral line neuromast mantle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000035 "Any neuromast mantle cell that is part of an anterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000035 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000035 "2014-06-25T03:44:44Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000035 "CL:2000035")
AnnotationAssertion(rdfs:label obo:CL_2000035 "anterior lateral line neuromast mantle cell")
EquivalentClasses(obo:CL_2000035 ObjectIntersectionOf(obo:CL_0000851 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_2001470)))

# Class: obo:CL_2000036 (anterior lateral line neuromast supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000036 "Any neuromast support cell that is part of a anterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000036 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000036 "2014-06-25T03:44:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000036 "anterior lateral line neuromast support cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000036 "CL:2000036")
AnnotationAssertion(rdfs:label obo:CL_2000036 "anterior lateral line neuromast supporting cell")
EquivalentClasses(obo:CL_2000036 ObjectIntersectionOf(obo:CL_0000852 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_2001470)))

# Class: obo:CL_2000037 (posterior lateral line neuromast hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000037 "Any neuromast hair cell that is part of a posterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000037 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000037 "2014-06-25T03:44:57Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000037 "CL:2000037")
AnnotationAssertion(rdfs:label obo:CL_2000037 "posterior lateral line neuromast hair cell")
EquivalentClasses(obo:CL_2000037 ObjectIntersectionOf(obo:CL_0000856 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006334)))

# Class: obo:CL_2000038 (posterior lateral line neuromast mantle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000038 "Any neuromast mantle cell that is part of a posterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000038 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000038 "2014-06-25T03:45:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000038 "CL:2000038")
AnnotationAssertion(rdfs:label obo:CL_2000038 "posterior lateral line neuromast mantle cell")
EquivalentClasses(obo:CL_2000038 ObjectIntersectionOf(obo:CL_0000851 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006334)))

# Class: obo:CL_2000039 (posterior lateral line neuromast supporting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000039 "Any neuromast support cell that is part of a posterior lateral line.")
AnnotationAssertion(terms:contributor obo:CL_2000039 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000039 "2014-06-25T03:45:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000039 "posterior lateral line neuromast support cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000039 "CL:2000039")
AnnotationAssertion(rdfs:label obo:CL_2000039 "posterior lateral line neuromast supporting cell")
EquivalentClasses(obo:CL_2000039 ObjectIntersectionOf(obo:CL_0000852 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006334)))

# Class: obo:CL_2000040 (bladder microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000040 "Any microvascular endothelial cell that is part of a urinary bladder.")
AnnotationAssertion(terms:contributor obo:CL_2000040 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000040 "2014-07-09T00:04:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000040 "CL:2000040")
AnnotationAssertion(rdfs:label obo:CL_2000040 "bladder microvascular endothelial cell")
EquivalentClasses(obo:CL_2000040 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001255)))

# Class: obo:CL_2000041 (dermis microvascular lymphatic vessel endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000041 "Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium.")
AnnotationAssertion(terms:contributor obo:CL_2000041 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000041 "2014-07-09T00:09:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000041 "CL:2000041")
AnnotationAssertion(rdfs:label obo:CL_2000041 "dermis microvascular lymphatic vessel endothelial cell")
EquivalentClasses(obo:CL_2000041 ObjectIntersectionOf(obo:CL_2000011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008339)))

# Class: obo:CL_2000042 (embryonic fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000042 "Any fibroblast that is part of a embryo.")
AnnotationAssertion(terms:contributor obo:CL_2000042 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000042 "2014-07-09T00:12:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000042 "CL:2000042")
AnnotationAssertion(rdfs:label obo:CL_2000042 "embryonic fibroblast")
EquivalentClasses(obo:CL_2000042 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922)))

# Class: obo:CL_2000043 (brain pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000043 "Any pericyte cell that is part of a brain.")
AnnotationAssertion(terms:contributor obo:CL_2000043 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000043 "2014-07-09T00:18:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000043 "CL:2000043")
AnnotationAssertion(rdfs:label obo:CL_2000043 "brain pericyte")
EquivalentClasses(obo:CL_2000043 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000955)))

# Class: obo:CL_2000044 (brain microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000044 "Any microvascular endothelial cell that is part of a brain.")
AnnotationAssertion(terms:contributor obo:CL_2000044 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000044 "2014-07-09T00:24:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000044 "CL:2000044")
AnnotationAssertion(rdfs:label obo:CL_2000044 "brain microvascular endothelial cell")
EquivalentClasses(obo:CL_2000044 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000955)))

# Class: obo:CL_2000045 (foreskin melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000045 "Any melanocyte of skin that is part of a skin of prepuce of penis.")
AnnotationAssertion(terms:contributor obo:CL_2000045 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(terms:contributor obo:CL_2000045 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000045 "2014-07-09T00:45:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000045 "melanocyte of foreskin")
AnnotationAssertion(oboInOwl:id obo:CL_2000045 "CL:2000045")
AnnotationAssertion(rdfs:label obo:CL_2000045 "foreskin melanocyte")
EquivalentClasses(obo:CL_2000045 ObjectIntersectionOf(obo:CL_1000458 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001471)))

# Class: obo:CL_2000046 (ventricular cardiac muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000046 "Any cardiac muscle cell that is part of a cardiac ventricle.")
AnnotationAssertion(terms:contributor obo:CL_2000046 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000046 "2014-08-12T20:50:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000046 "CL:2000046")
AnnotationAssertion(rdfs:label obo:CL_2000046 "ventricular cardiac muscle cell")
EquivalentClasses(obo:CL_2000046 ObjectIntersectionOf(obo:CL_0000746 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002082)))

# Class: obo:CL_2000047 (brainstem motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000047 "Any motor neuron that is part of a brainstem.")
AnnotationAssertion(terms:contributor obo:CL_2000047 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000047 "2014-10-02T23:52:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000047 "CL:2000047")
AnnotationAssertion(rdfs:label obo:CL_2000047 "brainstem motor neuron")
EquivalentClasses(obo:CL_2000047 ObjectIntersectionOf(obo:CL_0000100 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002298)))

# Class: obo:CL_2000048 (anterior horn motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-12-817962-8.00025-1") obo:IAO_0000115 obo:CL_2000048 "A lower motor neuron whose soma is located in the anterior horn. Anterior horn motor neurons project from the anterior portion of the grey matter in the spinal cord to some skeletal muscles.")
AnnotationAssertion(terms:contributor obo:CL_2000048 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000048 "2014-10-03T00:26:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000048 "NCIT:C12645")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000048 "anterior horn cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000048 "ventral horn of spinal cord spinal cord motor neuron")
AnnotationAssertion(oboInOwl:id obo:CL_2000048 "CL:2000048")
AnnotationAssertion(rdfs:comment obo:CL_2000048 "Yang & Connolly (DOI:10.1016/B978-0-323-37101-8.00140-5) classify these as alpha motor neurons.  Consider reflecting this if more references support this.")
AnnotationAssertion(rdfs:label obo:CL_2000048 "anterior horn motor neuron")
SubClassOf(obo:CL_2000048 obo:CL_0008039)
SubClassOf(obo:CL_2000048 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002257))

# Class: obo:CL_2000049 (primary motor cortex pyramidal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000049 "Any pyramidal cell that is part of a primary motor cortex.")
AnnotationAssertion(terms:contributor obo:CL_2000049 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000049 "2014-10-06T17:39:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000049 "CL:2000049")
AnnotationAssertion(rdfs:comment obo:CL_2000049 "http://www.ncbi.nlm.nih.gov/pubmed/12524689")
AnnotationAssertion(rdfs:label obo:CL_2000049 "primary motor cortex pyramidal cell")
EquivalentClasses(obo:CL_2000049 ObjectIntersectionOf(obo:CL_0000598 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))

# Class: obo:CL_2000050 (obsolete retina retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000050 "Any retinal ganglion cell that is part of a retina.")
AnnotationAssertion(terms:contributor obo:CL_2000050 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000050 "2014-10-06T17:43:59Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000050 "CL:2000050")
AnnotationAssertion(rdfs:comment obo:CL_2000050 "http://www.ncbi.nlm.nih.gov/pubmed/2889210")
AnnotationAssertion(rdfs:label obo:CL_2000050 "obsolete retina retinal ganglion cell")
AnnotationAssertion(owl:deprecated obo:CL_2000050 "true"^^xsd:boolean)

# Class: obo:CL_2000051 (splenic fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000051 "Any fibroblast that is part of a spleen.")
AnnotationAssertion(terms:contributor obo:CL_2000051 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000051 "2014-10-06T18:58:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000051 "CL:2000051")
AnnotationAssertion(rdfs:label obo:CL_2000051 "splenic fibroblast")
EquivalentClasses(obo:CL_2000051 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002106)))

# Class: obo:CL_2000052 (umbilical artery endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000052 "Any endothelial cell of artery that is part of a umbilical cord.")
AnnotationAssertion(terms:contributor obo:CL_2000052 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000052 "2014-10-06T19:01:48Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000052 "CL:2000052")
AnnotationAssertion(rdfs:comment obo:CL_2000052 "http://www.sciencellonline.com/site/productInformation.php?keyword=8010")
AnnotationAssertion(rdfs:label obo:CL_2000052 "umbilical artery endothelial cell")
EquivalentClasses(obo:CL_2000052 ObjectIntersectionOf(obo:CL_1000413 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002331)))

# Class: obo:CL_2000053 (splenic endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000053 "Any endothelial cell that is part of a spleen.")
AnnotationAssertion(terms:contributor obo:CL_2000053 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000053 "2014-10-06T19:06:04Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000053 "CL:2000053")
AnnotationAssertion(rdfs:comment obo:CL_2000053 "http://www.sciencellonline.com/site/productInformation.php?keyword=5500")
AnnotationAssertion(rdfs:label obo:CL_2000053 "splenic endothelial cell")
EquivalentClasses(obo:CL_2000053 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002106)))

# Class: obo:CL_2000054 (hepatic pit cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dos") Annotation(oboInOwl:hasDbXref "PMID:9408963") obo:IAO_0000115 obo:CL_2000054 "A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid.")
AnnotationAssertion(rdfs:comment obo:CL_2000054 "Pit cells are named for the presence of large cytoplasmic granules that resemble pits (pips) of fruit.")
AnnotationAssertion(rdfs:label obo:CL_2000054 "hepatic pit cell")
SubClassOf(obo:CL_2000054 obo:CL_0000623)
SubClassOf(obo:CL_2000054 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281))

# Class: obo:CL_2000055 (liver dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000055 "Any dendritic cell that is part of a liver.")
AnnotationAssertion(terms:contributor obo:CL_2000055 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000055 "2014-10-06T19:16:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000055 "hepatic dendritic cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000055 "CL:2000055")
AnnotationAssertion(rdfs:comment obo:CL_2000055 "http://www.jleukbio.org/content/66/2/322.abstract")
AnnotationAssertion(rdfs:label obo:CL_2000055 "liver dendritic cell")
EquivalentClasses(obo:CL_2000055 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107)))

# Class: obo:CL_2000056 (Meynert cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000056 "Any pyramidal cell that is part of a regional part of cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_2000056 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000056 "2014-10-06T19:20:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000056 "CL:2000056")
AnnotationAssertion(rdfs:label obo:CL_2000056 "Meynert cell")
SubClassOf(obo:CL_2000056 obo:CL_0000598)
SubClassOf(obo:CL_2000056 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))

# Class: obo:CL_2000057 (femoral osteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "PMID:34565180") Annotation(oboInOwl:hasDbXref "PMID:34569806") obo:IAO_0000115 obo:CL_2000057 "Any osteoblast that is part of a femur.")
AnnotationAssertion(terms:contributor obo:CL_2000057 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000057 "2014-10-06T19:29:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000057 "CL:2000057")
AnnotationAssertion(rdfs:label obo:CL_2000057 "femoral osteoblast")
EquivalentClasses(obo:CL_2000057 ObjectIntersectionOf(obo:CL_0000062 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000981)))

# Class: obo:CL_2000058 (calvarial osteoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000058 "Any osteoblast that is part of a skull.")
AnnotationAssertion(terms:contributor obo:CL_2000058 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000058 "2014-10-06T19:48:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000058 "CL:2000058")
AnnotationAssertion(rdfs:comment obo:CL_2000058 "http://www.sciencellonline.com/site/productInformation.php?keyword=4600")
AnnotationAssertion(rdfs:label obo:CL_2000058 "calvarial osteoblast")
EquivalentClasses(obo:CL_2000058 ObjectIntersectionOf(obo:CL_0000062 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003129)))

# Class: obo:CL_2000059 (prostate gland microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000059 "Any microvascular endothelial cell that is part of a prostate gland.")
AnnotationAssertion(terms:contributor obo:CL_2000059 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000059 "2014-10-07T17:46:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000059 "CL:2000059")
AnnotationAssertion(rdfs:comment obo:CL_2000059 "http://www.sciencellonline.com/site/productInformation.php?keyword=4400")
AnnotationAssertion(rdfs:label obo:CL_2000059 "prostate gland microvascular endothelial cell")
EquivalentClasses(obo:CL_2000059 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002367)))

# Class: obo:CL_2000060 (placental villous trophoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31049600") obo:IAO_0000115 obo:CL_2000060 "A trophoblast of placental villi.  These cells fuse to form synctial  trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua.")
AnnotationAssertion(terms:contributor obo:CL_2000060 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000060 "2014-10-07T17:48:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000060 "BTO:0006119")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_2000060 "BTO:0006208")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31049600") oboInOwl:hasExactSynonym obo:CL_2000060 "vCTB")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000060 "villous cytotrophoblast")
AnnotationAssertion(oboInOwl:id obo:CL_2000060 "CL:2000060")
AnnotationAssertion(rdfs:comment obo:CL_2000060 "Same as synctial trophoblast?")
AnnotationAssertion(rdfs:label obo:CL_2000060 "placental villous trophoblast")
AnnotationAssertion(rdfs:seeAlso obo:CL_2000060 "http://www.sciencellonline.com/site/productInformation.php?keyword=7120")
EquivalentClasses(obo:CL_2000060 ObjectIntersectionOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010005)))

# Class: obo:CL_2000061 (placental amniotic mesenchymal stromal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000061 "Any mesenchymal stem cell that is part of a placenta.")
AnnotationAssertion(terms:contributor obo:CL_2000061 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000061 "2014-10-07T17:51:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000061 "CL:2000061")
AnnotationAssertion(rdfs:comment obo:CL_2000061 "http://www.sciencellonline.com/site/productInformation.php?keyword=7140")
AnnotationAssertion(rdfs:label obo:CL_2000061 "placental amniotic mesenchymal stromal cell")
EquivalentClasses(obo:CL_2000061 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_2000062 (placental villus capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000062 "Any capillary endothelial cell that is part of a placenta.")
AnnotationAssertion(terms:contributor obo:CL_2000062 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000062 "2014-10-07T17:55:56Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000062 "CL:2000062")
AnnotationAssertion(rdfs:comment obo:CL_2000062 "http://www.ncbi.nlm.nih.gov/books/NBK53245/")
AnnotationAssertion(rdfs:label obo:CL_2000062 "placental villus capillary endothelial cell")
EquivalentClasses(obo:CL_2000062 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_2000063 (ovarian fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000063 "Any fibroblast that is part of a female gonad.")
AnnotationAssertion(terms:contributor obo:CL_2000063 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000063 "2014-10-07T17:57:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000063 "CL:2000063")
AnnotationAssertion(rdfs:comment obo:CL_2000063 "http://www.sciencellonline.com/site/productInformation.php?keyword=7330")
AnnotationAssertion(rdfs:label obo:CL_2000063 "ovarian fibroblast")
EquivalentClasses(obo:CL_2000063 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992)))

# Class: obo:CL_2000064 (ovarian surface epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "PMID:12052228") Annotation(oboInOwl:hasDbXref "PMID:15749958") Annotation(oboInOwl:hasDbXref "PMID:23467088") Annotation(oboInOwl:hasDbXref "PMID:31672973") Annotation(oboInOwl:hasDbXref "PMID:36205477") obo:IAO_0000115 obo:CL_2000064 "A meso-epithelial cell of the ovarian surface epithelium, varying in shape from flat to cuboidal to pseudostratified columnar. This cell plays a crucial role in ovulation by producing proteolytic enzymes in response to gonadotropins, facilitating follicle rupture through tissue breakdown and TNF-alpha signaling. Additionally, this cell contributes to post-ovulatory wound repair (Morris et al., 2022) and exhibits stem cell-like properties (Flesken-Nikitin et al., 2013; Wang et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_2000064 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000064 "2014-10-07T17:59:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000064 "CL:2000064")
AnnotationAssertion(rdfs:label obo:CL_2000064 "ovarian surface epithelial cell")
EquivalentClasses(obo:CL_2000064 ObjectIntersectionOf(obo:CL_0002078 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001304)))

# Class: obo:CL_2000065 (ovarian microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000065 "Any microvascular endothelial cell that is part of a female urethra.")
AnnotationAssertion(terms:contributor obo:CL_2000065 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000065 "2014-10-07T18:18:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000065 "CL:2000065")
AnnotationAssertion(rdfs:comment obo:CL_2000065 "http://www.sciencellonline.com/site/productInformation.php?keyword=7300")
AnnotationAssertion(rdfs:label obo:CL_2000065 "ovarian microvascular endothelial cell")
EquivalentClasses(obo:CL_2000065 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001334)))

# Class: obo:CL_2000066 (cardiac ventricle fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000066 "Any fibroblast that is part of a cardiac ventricle.")
AnnotationAssertion(terms:contributor obo:CL_2000066 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000066 "2014-10-07T18:35:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000066 "CL:2000066")
AnnotationAssertion(rdfs:comment obo:CL_2000066 "http://www.sciencellonline.com/site/productInformation.php?keyword=6310")
AnnotationAssertion(rdfs:label obo:CL_2000066 "cardiac ventricle fibroblast")
EquivalentClasses(obo:CL_2000066 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002082)))

# Class: obo:CL_2000067 (cardiac atrium fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000067 "Any fibroblast that is part of a cardiac atrium.")
AnnotationAssertion(terms:contributor obo:CL_2000067 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000067 "2014-10-07T18:36:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000067 "CL:2000067")
AnnotationAssertion(rdfs:comment obo:CL_2000067 "http://www.sciencellonline.com/site/productInformation.php?keyword=6320")
AnnotationAssertion(rdfs:label obo:CL_2000067 "cardiac atrium fibroblast")
EquivalentClasses(obo:CL_2000067 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002081)))

# Class: obo:CL_2000068 (pericardium fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000068 "Any fibroblast that is part of a pericardium.")
AnnotationAssertion(terms:contributor obo:CL_2000068 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000068 "2014-10-07T18:38:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000068 "CL:2000068")
AnnotationAssertion(rdfs:comment obo:CL_2000068 "http://www.sciencellonline.com/site/productInformation.php?keyword=6430")
AnnotationAssertion(rdfs:label obo:CL_2000068 "pericardium fibroblast")
EquivalentClasses(obo:CL_2000068 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002407)))

# Class: obo:CL_2000069 (gallbladder fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000069 "Any fibroblast that is part of a gallbladder.")
AnnotationAssertion(terms:contributor obo:CL_2000069 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000069 "2014-10-07T18:41:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000069 "CL:2000069")
AnnotationAssertion(rdfs:comment obo:CL_2000069 "http://www.sciencellonline.com/site/productInformation.php?keyword=5430")
AnnotationAssertion(rdfs:label obo:CL_2000069 "gallbladder fibroblast")
EquivalentClasses(obo:CL_2000069 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002110)))

# Class: obo:CL_2000070 (optic choroid fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000070 "Any fibroblast that is part of a optic choroid.")
AnnotationAssertion(terms:contributor obo:CL_2000070 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000070 "2014-10-07T18:50:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000070 "CL:2000070")
AnnotationAssertion(rdfs:comment obo:CL_2000070 "http://www.sciencellonline.com/site/productInformation.php?keyword=6620")
AnnotationAssertion(rdfs:label obo:CL_2000070 "optic choroid fibroblast")
EquivalentClasses(obo:CL_2000070 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001776)))

# Class: obo:CL_2000071 (mammary microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000071 "Any microvascular endothelial cell that is part of a breast.")
AnnotationAssertion(terms:contributor obo:CL_2000071 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000071 "2014-10-07T19:55:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000071 "CL:2000071")
AnnotationAssertion(rdfs:comment obo:CL_2000071 "http://www.sciencellonline.com/site/productInformation.php?keyword=7600")
AnnotationAssertion(rdfs:label obo:CL_2000071 "mammary microvascular endothelial cell")
EquivalentClasses(obo:CL_2000071 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000310)))

# Class: obo:CL_2000072 (adipose microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000072 "Any microvascular endothelial cell that is part of a adipose tissue.")
AnnotationAssertion(terms:contributor obo:CL_2000072 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000072 "2014-10-07T22:13:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000072 "CL:2000072")
AnnotationAssertion(rdfs:comment obo:CL_2000072 "http://www.sciencellonline.com/site/productInformation.php?keyword=7200")
AnnotationAssertion(rdfs:label obo:CL_2000072 "adipose microvascular endothelial cell")
EquivalentClasses(obo:CL_2000072 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001013)))

# Class: obo:CL_2000073 (migratory cardiac neural crest cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000073 "Any migratory neural crest cell that is part of a cardiac neural crest.")
AnnotationAssertion(terms:contributor obo:CL_2000073 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000073 "2014-11-05T01:18:43Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33060096") oboInOwl:hasExactSynonym obo:CL_2000073 "cardiac neural crest cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000073 "CL:2000073")
AnnotationAssertion(rdfs:label obo:CL_2000073 "migratory cardiac neural crest cell")
EquivalentClasses(obo:CL_2000073 ObjectIntersectionOf(obo:CL_0000333 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000095)))

# Class: obo:CL_2000074 (splenocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000074 "Any leukocyte that is part of a spleen.")
AnnotationAssertion(terms:contributor obo:CL_2000074 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000074 "2014-11-05T01:26:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000074 "CL:2000074")
AnnotationAssertion(rdfs:comment obo:CL_2000074 "Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology.")
AnnotationAssertion(rdfs:label obo:CL_2000074 "splenocyte")
EquivalentClasses(obo:CL_2000074 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002106)))

# Class: obo:CL_2000075 (anterior visceral endoderm cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000075 "Any endodermal cell that is part of a anterior visceral endoderm.")
AnnotationAssertion(terms:contributor obo:CL_2000075 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000075 "2014-11-05T01:34:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000075 "CL:2000075")
AnnotationAssertion(rdfs:label obo:CL_2000075 "anterior visceral endoderm cell")
EquivalentClasses(obo:CL_2000075 ObjectIntersectionOf(obo:CL_0000223 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004044)))

# Class: obo:CL_2000076 (hindlimb stylopod vein endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000076 "Any vein endothelial cell that is part of a hindlimb stylopod.")
AnnotationAssertion(terms:contributor obo:CL_2000076 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000076 "2014-12-02T18:40:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000076 "CL:2000076")
AnnotationAssertion(rdfs:label obo:CL_2000076 "hindlimb stylopod vein endothelial cell")
EquivalentClasses(obo:CL_2000076 ObjectIntersectionOf(obo:CL_0002543 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000376)))

# Class: obo:CL_2000077 (skeletal muscle tissue of pectoralis major striated muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000077 "Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major.")
AnnotationAssertion(terms:contributor obo:CL_2000077 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000077 "2014-12-02T18:48:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000077 "CL:2000077")
AnnotationAssertion(rdfs:label obo:CL_2000077 "skeletal muscle tissue of pectoralis major striated muscle cell")
EquivalentClasses(obo:CL_2000077 ObjectIntersectionOf(obo:CL_0000737 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004510)))

# Class: obo:CL_2000078 (placental pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000078 "Any pericyte cell that is part of a placenta.")
AnnotationAssertion(terms:contributor obo:CL_2000078 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000078 "2014-12-02T18:51:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000078 "CL:2000078")
AnnotationAssertion(rdfs:label obo:CL_2000078 "placental pericyte")
EquivalentClasses(obo:CL_2000078 ObjectIntersectionOf(obo:CL_0000669 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_2000079 (mesenchymal stem cell of femoral bone marrow)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000079 "Any mesenchymal stem cell of the bone marrow that is part of a femur.")
AnnotationAssertion(terms:contributor obo:CL_2000079 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000079 "2014-12-02T19:07:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000079 "CL:2000079")
AnnotationAssertion(rdfs:label obo:CL_2000079 "mesenchymal stem cell of femoral bone marrow")
EquivalentClasses(obo:CL_2000079 ObjectIntersectionOf(obo:CL_0002540 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000981)))

# Class: obo:CL_2000080 (mesenchymal stem cell of abdominal adipose tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000080 "Any mesenchymal stem cell of adipose tissue that is part of an abdomen.")
AnnotationAssertion(terms:contributor obo:CL_2000080 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000080 "2014-12-02T19:10:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000080 "mesenchymal stem cell of abdominal adipose")
AnnotationAssertion(oboInOwl:id obo:CL_2000080 "CL:2000080")
AnnotationAssertion(rdfs:label obo:CL_2000080 "mesenchymal stem cell of abdominal adipose tissue")
EquivalentClasses(obo:CL_2000080 ObjectIntersectionOf(obo:CL_0002570 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000916)))

# Class: obo:CL_2000081 (melanocyte of skin of face)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000081 "Any melanocyte of skin that is part of a skin of face.")
AnnotationAssertion(terms:contributor obo:CL_2000081 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000081 "2014-12-02T19:10:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000081 "CL:2000081")
AnnotationAssertion(rdfs:label obo:CL_2000081 "melanocyte of skin of face")
EquivalentClasses(obo:CL_2000081 ObjectIntersectionOf(obo:CL_1000458 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_1000021)))

# Class: obo:CL_2000082 (obsolete melanocyte of foreskin)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000082 "OBSOLETE. Any melanocyte of skin that is part of a skin of prepuce of penis.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_2000082 <https://github.com/obophenotype/cell-ontology/issues/1562>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_2000082 obo:CL_2000045)
AnnotationAssertion(terms:contributor obo:CL_2000082 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000082 "2014-12-02T19:10:45Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000082 "CL:2000082")
AnnotationAssertion(rdfs:comment obo:CL_2000082 "Term was merged into foreskin melanocyte CL_2000045")
AnnotationAssertion(rdfs:label obo:CL_2000082 "obsolete melanocyte of foreskin")
AnnotationAssertion(owl:deprecated obo:CL_2000082 "true"^^xsd:boolean)

# Class: obo:CL_2000083 (hair follicle dermal papilla cell of scalp)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000083 "Any hair follicle dermal papilla cell that is part of a scalp.")
AnnotationAssertion(terms:contributor obo:CL_2000083 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000083 "2014-12-02T19:10:50Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000083 "CL:2000083")
AnnotationAssertion(rdfs:label obo:CL_2000083 "hair follicle dermal papilla cell of scalp")
EquivalentClasses(obo:CL_2000083 ObjectIntersectionOf(obo:CL_0000346 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000403)))

# Class: obo:CL_2000084 (conjunctiva goblet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "PMID:27091323") Annotation(oboInOwl:hasDbXref "PMID:28475124") Annotation(oboInOwl:hasDbXref "PMID:31734511") obo:IAO_0000115 obo:CL_2000084 "A goblet cell that is part of the conjunctival epithelium, characterized by apical accumulation of mucin granules (containing MUC5AC in humans; Muc5ac/Muc5b in mice). These gel-forming mucins support tear film stability, ocular lubrication, and pathogen defence. The conjunctival goblet cell forms tight junctions with neighbouring epithelial cells via species-specific claudins (claudin-10 in humans, claudin-2 in mice) and regulates immune homeostasis by facilitating soluble antigen transport to dendritic cells through goblet cell-associated antigen passages (GAPs) (Barbosa et al., 2017). The transcription factor SPDEF is essential for its differentiation.")
AnnotationAssertion(terms:contributor obo:CL_2000084 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000084 "2014-12-02T19:28:38Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31734511") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_2000084 "CGC")
AnnotationAssertion(rdfs:label obo:CL_2000084 "conjunctiva goblet cell")
EquivalentClasses(obo:CL_2000084 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006763)))

# Class: obo:CL_2000085 (mononuclear cell of umbilical cord)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000085 "Any mononuclear cell that is part of a umbilical cord.")
AnnotationAssertion(terms:contributor obo:CL_2000085 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000085 "2014-12-02T20:14:16Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000085 "CL:2000085")
AnnotationAssertion(rdfs:label obo:CL_2000085 "mononuclear cell of umbilical cord")
EquivalentClasses(obo:CL_2000085 ObjectIntersectionOf(obo:CL_0000842 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002331)))

# Class: obo:CL_2000086 (neocortex basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000086 "Any basket cell that is part of a neocortex.")
AnnotationAssertion(terms:contributor obo:CL_2000086 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000086 "2014-12-24T00:37:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000086 "CL:2000086")
AnnotationAssertion(rdfs:label obo:CL_2000086 "neocortex basket cell")
EquivalentClasses(obo:CL_2000086 ObjectIntersectionOf(obo:CL_0000118 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001950)))

# Class: obo:CL_2000087 (dentate gyrus of hippocampal formation basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000087 "Any basket cell that is part of a dentate gyrus of hippocampal formation.")
AnnotationAssertion(terms:contributor obo:CL_2000087 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000087 "2014-12-24T00:37:24Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000087 "CL:2000087")
AnnotationAssertion(rdfs:label obo:CL_2000087 "dentate gyrus of hippocampal formation basket cell")
EquivalentClasses(obo:CL_2000087 ObjectIntersectionOf(obo:CL_0000118 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001885)))

# Class: obo:CL_2000088 (Ammon's horn basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000088 "Any basket cell that is part of a Ammon's horn.")
AnnotationAssertion(terms:contributor obo:CL_2000088 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000088 "2014-12-24T00:37:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000088 "CL:2000088")
AnnotationAssertion(rdfs:label obo:CL_2000088 "Ammon's horn basket cell")
EquivalentClasses(obo:CL_2000088 ObjectIntersectionOf(obo:CL_0000118 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001954)))

# Class: obo:CL_2000089 (dentate gyrus granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "PMID:17765709") obo:IAO_0000115 obo:CL_2000089 "A granule cell that has soma location in the dentate gyrus cell layer of the hippocampal formation and has an elliptical cell body and characteristic cone-shaped tree of spiny apical dendrites. The branches extend throughout the molecular layer and the distal tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. The dentate gyrus granule cell is the principal cell type of the dentate gyrus.")
AnnotationAssertion(terms:contributor obo:CL_2000089 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000089 "2015-02-23T05:48:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_2000089 "dentate gyrus of hippocampal formation granule cell")
AnnotationAssertion(oboInOwl:id obo:CL_2000089 "CL:2000089")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17765709") rdfs:comment obo:CL_2000089 "As far as can be determined, all dentate granule cells appear to project to CA3 and the axon trajectory is partially correlated with the position of the parent cell body.")
AnnotationAssertion(rdfs:label obo:CL_2000089 "dentate gyrus granule cell")
EquivalentClasses(obo:CL_2000089 ObjectIntersectionOf(obo:CL_0001033 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005381)))

# Class: obo:CL_2000090 (dentate gyrus of hippocampal formation stellate cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000090 "Any stellate cell that is part of a dentate gyrus of hippocampal formation.")
AnnotationAssertion(terms:contributor obo:CL_2000090 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000090 "2015-02-23T05:48:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000090 "CL:2000090")
AnnotationAssertion(rdfs:label obo:CL_2000090 "dentate gyrus of hippocampal formation stellate cell")
EquivalentClasses(obo:CL_2000090 ObjectIntersectionOf(obo:CL_0000122 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001885)))

# Class: obo:CL_2000091 (endometrial microvascular endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000091 "Any microvascular endothelial cell that is part of a endometrial blood vessel.")
AnnotationAssertion(terms:contributor obo:CL_2000091 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000091 "2015-03-31T21:02:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000091 "CL:2000091")
AnnotationAssertion(rdfs:label obo:CL_2000091 "endometrial microvascular endothelial cell")
EquivalentClasses(obo:CL_2000091 ObjectIntersectionOf(obo:CL_2000008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015172)))

# Class: obo:CL_2000092 (hair follicular keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000092 "Any keratinocyte that is part of a hair follicle.")
AnnotationAssertion(terms:contributor obo:CL_2000092 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000092 "2015-03-31T21:07:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000092 "CL:2000092")
AnnotationAssertion(rdfs:label obo:CL_2000092 "hair follicular keratinocyte")
EquivalentClasses(obo:CL_2000092 ObjectIntersectionOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073)))

# Class: obo:CL_2000093 (bronchus fibroblast of lung)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000093 "Any fibroblast of lung that is part of a bronchus.")
AnnotationAssertion(terms:contributor obo:CL_2000093 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000093 "2015-03-31T21:16:22Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000093 "CL:2000093")
AnnotationAssertion(rdfs:label obo:CL_2000093 "bronchus fibroblast of lung")
EquivalentClasses(obo:CL_2000093 ObjectIntersectionOf(obo:CL_0002553 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002185)))

# Class: obo:CL_2000094 (nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000094 "Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium.")
AnnotationAssertion(terms:contributor obo:CL_2000094 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000094 "2015-03-31T22:25:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000094 "CL:2000094")
AnnotationAssertion(rdfs:label obo:CL_2000094 "nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa")
EquivalentClasses(obo:CL_2000094 ObjectIntersectionOf(obo:CL_1000441 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005385)))

# Class: obo:CL_2000095 (cord blood hematopoietic stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000095 "Any hematopoietic stem cell that is part of a umbilical cord blood.")
AnnotationAssertion(terms:contributor obo:CL_2000095 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000095 "2015-05-26T18:58:34Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000095 "CL:2000095")
AnnotationAssertion(rdfs:label obo:CL_2000095 "cord blood hematopoietic stem cell")
EquivalentClasses(obo:CL_2000095 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012168)))

# Class: obo:CL_2000096 (fibroblast of the reticular layer of dermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") Annotation(oboInOwl:hasDbXref "PMID:29266210") Annotation(oboInOwl:hasDbXref "PMID:35212000") Annotation(oboInOwl:hasDbXref "PMID:36232952") Annotation(oboInOwl:hasDbXref "PMID:37646029") obo:IAO_0000115 obo:CL_2000096 "A fibroblast of dermis that resides in the deep reticular layer, characterised by robust extracellular matrix production with high type I collagen deposition forming densely packed, organised fibrillar networks (Ghetti et al., 2018). This cell exhibits pro-fibrotic properties during wound healing, entering wounds early where it proliferates and deposits collagen to restore dermal architecture (Knoedler et al., 2023; McAndrews et al., 2022). It is distinguished from papillary dermal fibroblasts by expression of COL11A1, POSTN, and SPP1 in humans (Wu et al., 2022).")
AnnotationAssertion(terms:contributor obo:CL_2000096 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(terms:contributor obo:CL_2000096 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000096 "2015-08-11T16:28:16Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29266210") oboInOwl:hasRelatedSynonym obo:CL_2000096 "reticular fibroblast")
AnnotationAssertion(oboInOwl:id obo:CL_2000096 "CL:2000096")
AnnotationAssertion(rdfs:label obo:CL_2000096 "fibroblast of the reticular layer of dermis")
EquivalentClasses(obo:CL_2000096 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001993)))
SubClassOf(obo:CL_2000096 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))
SubClassOf(obo:CL_2000096 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q15063))
SubClassOf(obo:CL_2000096 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0005584))

# Class: obo:CL_2000097 (midbrain dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000097 "Any dopaminergic neuron that is part of a midbrain.")
AnnotationAssertion(terms:contributor obo:CL_2000097 <http://www.wikidata.org/entity/Q35563349>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_2000097 "2015-12-03T16:42:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_2000097 "CL:2000097")
AnnotationAssertion(rdfs:label obo:CL_2000097 "midbrain dopaminergic neuron")
EquivalentClasses(obo:CL_2000097 ObjectIntersectionOf(obo:CL_0000700 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001891)))

# Class: obo:CL_3000000 (ciliated epithelial cell of esophagus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "PMID:29802404") obo:IAO_0000115 obo:CL_3000000 "A ciliated epithelial cell of the esophagus.")
AnnotationAssertion(terms:contributor obo:CL_3000000 <http://www.wikidata.org/entity/Q97529981>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_3000000 "2019-02-09T16:40:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_3000000 "CL:3000000")
AnnotationAssertion(rdfs:label obo:CL_3000000 "ciliated epithelial cell of esophagus")
SubClassOf(obo:CL_3000000 obo:CL_0002252)
SubClassOf(obo:CL_3000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001976))

# Class: obo:CL_3000001 (Hofbauer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "PMID:30429548") Annotation(oboInOwl:hasDbXref "PMID:30498493") Annotation(oboInOwl:hasDbXref "PMID:34745147") Annotation(oboInOwl:hasDbXref "PMID:35438172") obo:IAO_0000115 obo:CL_3000001 "A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin, is found in the villous stroma, chorion, and amnion, and is present throughout pregnancy.")
AnnotationAssertion(terms:contributor obo:CL_3000001 <http://www.wikidata.org/entity/Q97529981>)
AnnotationAssertion(terms:contributor obo:CL_3000001 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_3000001 "2019-02-18T19:41:20Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") oboInOwl:hasExactSynonym obo:CL_3000001 "fetal Hofbauer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_3000001 "HBC")
AnnotationAssertion(oboInOwl:id obo:CL_3000001 "CL:3000001")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30498493") rdfs:comment obo:CL_3000001 "Hofbauer cells are a heterogenic group of macrophages that resemble M2-like cells. Initially described in chorionic villi in humans, a Hofbauer cell is now often used to describe any fetal-derived placental macrophage that resides within the placental villous core, amnion, and chorion laeve.")
AnnotationAssertion(rdfs:label obo:CL_3000001 "Hofbauer cell")
SubClassOf(obo:CL_3000001 obo:CL_4033087)

# Class: obo:CL_3000002 (sympathetic noradrenergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:IAO_0000115 obo:CL_3000002 "Sympathetic noradrenergic neuron.")
AnnotationAssertion(terms:contributor obo:CL_3000002 <http://www.wikidata.org/entity/Q97529981>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_3000002 "2019-02-25T19:30:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_3000002 "CL:3000002")
AnnotationAssertion(rdfs:label obo:CL_3000002 "sympathetic noradrenergic neuron")
EquivalentClasses(obo:CL_3000002 ObjectIntersectionOf(obo:CL_0011103 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061533)))

# Class: obo:CL_3000003 (sympathetic cholinergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:IAO_0000115 obo:CL_3000003 "A type of autonomic neuron that releases acetylcholine.")
AnnotationAssertion(terms:contributor obo:CL_3000003 <http://www.wikidata.org/entity/Q97529981>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_3000003 "2019-02-25T19:32:20Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_3000003 "CL:3000003")
AnnotationAssertion(rdfs:label obo:CL_3000003 "sympathetic cholinergic neuron")
EquivalentClasses(obo:CL_3000003 ObjectIntersectionOf(obo:CL_0011103 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055)))

# Class: obo:CL_3000004 (peripheral sensory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:CellBLAST") Annotation(oboInOwl:hasDbXref "PMID:30096314") Annotation(oboInOwl:hasDbXref "PMID:31554486") Annotation(oboInOwl:hasDbXref "PMID:35858549") Annotation(oboInOwl:hasDbXref "Wikipedia:Sensory_neuron") Annotation(oboInOwl:hasDbXref "https://www.britannica.com/science/sensory-neuron") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK539846/") obo:IAO_0000115 obo:CL_3000004 "A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing.")
AnnotationAssertion(terms:contributor obo:CL_3000004 <http://www.wikidata.org/entity/Q97529981>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_3000004 "2019-02-25T19:34:33Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:id obo:CL_3000004 "CL:3000004")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Sensory_neuron") rdfs:comment obo:CL_3000004 "Typically, a sensory neuron has a pseudounipolar morphology.")
AnnotationAssertion(rdfs:label obo:CL_3000004 "peripheral sensory neuron")
EquivalentClasses(obo:CL_3000004 ObjectIntersectionOf(obo:CL_2000032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))

# Class: obo:CL_4006000 (fibroblast of breast)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4006000 "A fibroblast that is part of the breast.")
AnnotationAssertion(terms:contributor obo:CL_4006000 <https://orcid.org/0000-0001-9897-3238>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4006000 "breast fibroblast")
AnnotationAssertion(rdfs:label obo:CL_4006000 "fibroblast of breast")
EquivalentClasses(obo:CL_4006000 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000310)))
SubClassOf(obo:CL_4006000 obo:CL_0000057)

# Class: obo:CL_4006001 (fibroblast of skin of scalp)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4006001 "A fibroblast that is part of the skin of scalp.")
AnnotationAssertion(terms:contributor obo:CL_4006001 <https://orcid.org/0000-0001-9897-3238>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4006001 "skin of scalp fibroblast")
AnnotationAssertion(rdfs:label obo:CL_4006001 "fibroblast of skin of scalp")
EquivalentClasses(obo:CL_4006001 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8300000)))
SubClassOf(obo:CL_4006001 obo:CL_0000057)

# Class: obo:CL_4023000 (beta motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25346659") obo:IAO_0000115 obo:CL_4023000 "A motor neuron that innervates both intrafusal and extrafusal muscle fibers. Low abundancy. They control both muscle contraction and responsiveness of the sensory feedback from muscle spindles.")
AnnotationAssertion(terms:contributor obo:CL_4023000 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023000 "beta motor neuron")
SubClassOf(obo:CL_4023000 obo:CL_0008039)
SubClassOf(obo:CL_4023000 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008046))
SubClassOf(obo:CL_4023000 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008047))

# Class: obo:CL_4023001 (static beta motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25346659") obo:IAO_0000115 obo:CL_4023001 "A beta motor neuron that innervates nuclear chain fibers.")
AnnotationAssertion(terms:contributor obo:CL_4023001 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023001 "static beta motor neuron")
SubClassOf(obo:CL_4023001 obo:CL_4023000)

# Class: obo:CL_4023002 (dynamic beta motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25346659") obo:IAO_0000115 obo:CL_4023002 "A beta motor neuron that innervates the nuclear bag fibers of muscle spindles.")
AnnotationAssertion(terms:contributor obo:CL_4023002 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023002 "dynamic beta motor neuron")
SubClassOf(obo:CL_4023002 obo:CL_4023000)

# Class: obo:CL_4023003 (nuclear chain fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-323-39632-5.00024-4") Annotation(oboInOwl:hasDbXref "PMID:139469") obo:IAO_0000115 obo:CL_4023003 "A type of intrafusal muscle fiber that has nuclei arranged in a linear row. Unlike nuclear bag fibers, the equatorial region of these fibers (in the centre of the spindle) is not expanded. These fibers are responsible for the detection of changes in muscle length. They are innervated by static gamma motor neurons and are principally associated with type II sensory fibers.")
AnnotationAssertion(terms:contributor obo:CL_4023003 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023003 "nuclear chain fiber")
SubClassOf(obo:CL_4023003 obo:CL_0008047)

# Class: obo:CL_4023004 (nuclear bag fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-323-39632-5.00024-4") Annotation(oboInOwl:hasDbXref "PMID:139469") obo:IAO_0000115 obo:CL_4023004 "A type of intrafusal muscle fiber that lies in the center of a muscle spindle. Nuclei are clustered centrally and give the equatorial region a swollen appearance. They are associated with associated with dynamic gamma motor neurons, and the stretching of the equatorial region of the nuclear bag fibers results in an increase in the firing rate of type Ia sensory fibers.")
AnnotationAssertion(terms:contributor obo:CL_4023004 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023004 "nuclear bag fiber")
SubClassOf(obo:CL_4023004 obo:CL_0008047)

# Class: obo:CL_4023005 (dynamic nuclear bag fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-323-39632-5.00024-4") obo:IAO_0000115 obo:CL_4023005 "A nuclear bag fiber that is sensitive mainly to the rate of change in muscle length.")
AnnotationAssertion(terms:contributor obo:CL_4023005 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023005 "bag1 fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023005 "nuclear bag1 intrafusal fiber")
AnnotationAssertion(rdfs:label obo:CL_4023005 "dynamic nuclear bag fiber")
SubClassOf(obo:CL_4023005 obo:CL_4023004)

# Class: obo:CL_4023006 (static nuclear bag fiber)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/B978-0-323-39632-5.00024-4") obo:IAO_0000115 obo:CL_4023006 "A nuclear bag fiber that is sensitive only changes in muscle length but not the rate of that change.")
AnnotationAssertion(terms:contributor obo:CL_4023006 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023006 "bag2 fiber")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023006 "nuclear bag2 intrafusal fiber")
AnnotationAssertion(rdfs:label obo:CL_4023006 "static nuclear bag fiber")
SubClassOf(obo:CL_4023006 obo:CL_4023004)

# Class: obo:CL_4023007 (L2/3 bipolar VIP GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023007 "L2/3 bipolar VIP interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26420784") obo:IAO_0000115 obo:CL_4023007 "A VIP GABAergic cortical interneuron with bipolar morphology, with a soma found in L2/3. L2/3 bipolar VIP cells have extending axons across all layers (with preferences for layers II/III and Va) and a dendritic tree that is vertically more restricted than deeper layer VIP cells and extend fewer dendrites into the layers outside their home layer (location of soma). L2/3 bipolar VIP cells have great variability in firing patterns, though most are continuous adapting. L2/3 bipolar VIP cells are more depolarized in their resting state, had less fast rectification, and had smaller after hyperpolarization than deeper VIP cells.")
AnnotationAssertion(terms:contributor obo:CL_4023007 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023007 "L2/3 bipolar Vip (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023007 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023007 "L2/3 bipolar VIP GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023007 obo:CL_0000099)
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070006))
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440000))
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023007 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P32648))

# Class: obo:CL_4023008 (intratelencephalic-projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023008 "IT neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") obo:IAO_0000115 obo:CL_4023008 "A glutamatergic neuron located in the cerebral cortex that projects to structures of telencephalic origins.")
AnnotationAssertion(terms:contributor obo:CL_4023008 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023008 "ILX:0770100")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-021-24565-z") oboInOwl:hasExactSynonym obo:CL_4023008 "IT neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023008 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023008 "intratelencephalic-projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023008 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070034) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_4023009 (extratelencephalic-projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023009 "ET glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") obo:IAO_0000115 obo:CL_4023009 "A glutamatergic neuron located in the cerebral cortex that projects to structures not derived from telencephalon.")
AnnotationAssertion(terms:contributor obo:CL_4023009 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023009 "ILX:0770101")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023009 "ET projecting neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023009 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023009 "extratelencephalic-projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023009 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070028) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_4023010 (alpha7 GABAergic cortical interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023010 "A7 interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30413647") Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023010 "A GABAergic cortical interneuron that is strongly labelled for α7 nAChRs. These cells have soma found in L1 and have multipolar dendrites with vertically descending axonal collaterals that project deep into the column, usually branching and terminating in L5A.")
AnnotationAssertion(terms:contributor obo:CL_4023010 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023010 "A7 cell (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023010 cl:BDS_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") Annotation(oboInOwl:hasDbXref "PMID:30413647") Annotation(oboInOwl:hasDbXref "PMID:33184512") rdfs:comment obo:CL_4023010 "Unlike typical Lamp5 electrophysiology, A7 cells have Vip- and Sst-like firing properties, with active depolarizing hump at near-threshold membrane potentials, and  larger hyperpolarization sag, stronger burst, and rebound firing. A7 cells have a transcriptomics signature that looks like Lamp5 GABAergic interneuron.")
AnnotationAssertion(rdfs:label obo:CL_4023010 "alpha7 GABAergic cortical interneuron (Mmus)")
SubClassOf(obo:CL_4023010 obo:CL_0000099)
SubClassOf(obo:CL_4023010 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023010 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023010 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023010 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000005460))

# Class: obo:CL_4023011 (lamp5 GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023011 "Lamp5 interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4023011 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5.")
AnnotationAssertion(terms:contributor obo:CL_4023011 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023011 "ILX:0770149")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023011 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023011 "lamp5 GABAergic interneuron")
EquivalentClasses(obo:CL_4023011 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000032148)))
SubClassOf(obo:CL_4023011 obo:CL_4023064)
SubClassOf(obo:CL_4023011 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026))

# Class: obo:CL_4023012 (near-projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023012 "NP glut neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") obo:IAO_0000115 obo:CL_4023012 "A glutamatergic neuron located in the cerebral cortex that projects axons locally rather than distantly.")
AnnotationAssertion(terms:contributor obo:CL_4023012 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023012 "ILX:0770103")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023012 "NP neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023012 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023012 "near-projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023012 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070030) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_4023013 (corticothalamic-projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023013 "CT glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") obo:IAO_0000115 obo:CL_4023013 "A glutamatergic neuron located in the cerebral cortex that projects to the thalamus.")
AnnotationAssertion(terms:contributor obo:CL_4023013 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023013 "CT projecting neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023013 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023013 "corticothalamic-projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023013 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070029) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_4023014 (L5 VIP GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023014 "L5 VIP interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26420784") Annotation(oboInOwl:hasDbXref "PMID:26612957") obo:IAO_0000115 obo:CL_4023014 "A VIP GABAergic cortical interneuron with a soma found in L5. L5 VIP cells have mostly local morphology with some deep-projecting axons. They show only moderate resistance, comparable to that of sst subclass and unlike typical VIP subclass cells that tend to show high input resistance. L5 VIP cells show particularly low resting membrane potential.")
AnnotationAssertion(terms:contributor obo:CL_4023014 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023014 "L5 VIP (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023014 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023014 "L5 VIP GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023014 obo:CL_0000099)
SubClassOf(obo:CL_4023014 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005394))
SubClassOf(obo:CL_4023014 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023014 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023014 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P32648))

# Class: obo:CL_4023015 (sncg GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023015 "sncg interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33186530") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4023015 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein.")
AnnotationAssertion(terms:contributor obo:CL_4023015 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023015 "ILX:0770150")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023015 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023015 "sncg GABAergic interneuron")
EquivalentClasses(obo:CL_4023015 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015325)))
SubClassOf(obo:CL_4023015 obo:CL_4023064)
SubClassOf(obo:CL_4023015 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015325))

# Class: obo:CL_4023016 (VIP GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023016 "VIP interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33186530") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4023016 "A transcriptomically distinct GABAergic neuron derived from the CGE and that expresses the vasoactive intestinal polypeptide. Its soma is located in the forebrain.")
AnnotationAssertion(terms:contributor obo:CL_4023016 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33108272") oboInOwl:hasBroadSynonym obo:CL_4023016 "VIP interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33108272") oboInOwl:hasBroadSynonym obo:CL_4023016 "VIP neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35221922") oboInOwl:hasBroadSynonym obo:CL_4023016 "VIP-Expressing GABAergic Neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ILX:0770151") oboInOwl:hasBroadSynonym obo:CL_4023016 "Vip GABAergic neuron")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023016 "ILX:0770151")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36384143") oboInOwl:hasRelatedSynonym obo:CL_4023016 "VIP neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") oboInOwl:hasRelatedSynonym obo:CL_4023016 "VIP type")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33794534") oboInOwl:hasRelatedSynonym obo:CL_4023016 "VIP-IN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ILX:0770151") oboInOwl:hasRelatedSynonym obo:CL_4023016 "Vip")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023016 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023016 "VIP GABAergic interneuron")
EquivalentClasses(obo:CL_4023016 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000017299)))
SubClassOf(obo:CL_4023016 obo:CL_4023064)
SubClassOf(obo:CL_4023016 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001890))
SubClassOf(obo:CL_4023016 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026))
SubClassOf(obo:CL_4023016 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000017299))

# Class: obo:CL_4023017 (sst GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023017 "sst interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:33742131") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4023017 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst) and derived from the MGE.")
AnnotationAssertion(terms:contributor obo:CL_4023017 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023017 "ILX:0770152")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30001424") oboInOwl:hasRelatedSynonym obo:CL_4023017 "SOM+ inhibitory interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33742131") oboInOwl:hasRelatedSynonym obo:CL_4023017 "SST+ IN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30001424") oboInOwl:hasRelatedSynonym obo:CL_4023017 "somatostatin-expressing inhibitory interneuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023017 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023017 "sst GABAergic interneuron")
EquivalentClasses(obo:CL_4023017 ObjectIntersectionOf(obo:CL_4023069 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015665)))
SubClassOf(obo:CL_4023017 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000203))
SubClassOf(obo:CL_4023017 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024))

# Class: obo:CL_4023018 (pvalb GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023018 "pvalb interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4023018 "A transcriptomically distinct GABAergic interneuron with a soma located in the pallium. These neurons express Parvalbumin.")
AnnotationAssertion(terms:contributor obo:CL_4023018 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023018 "ILX:0770154")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023018 cl:BDS_subset)
AnnotationAssertion(rdfs:comment obo:CL_4023018 "Historically this term was used to refer to all Pvalb expressing GABAergic interneurons, but transcriptomic classification separates out some Pvalb expressing GABAergic interneurons as sibling classes (e.g. Pvalb chandelier).  We follow the transcriptomic classifications.")
AnnotationAssertion(rdfs:label obo:CL_4023018 "pvalb GABAergic interneuron")
SubClassOf(obo:CL_4023018 obo:CL_0000099)
SubClassOf(obo:CL_4023018 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000203))
SubClassOf(obo:CL_4023018 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024))
SubClassOf(obo:CL_4023018 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023018 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013502))

# Class: obo:CL_4023019 (L5/6 cck, VIP GABAergic interneuron (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023019 "A VIP GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization.")
AnnotationAssertion(terms:contributor obo:CL_4023019 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023019 "L5/6 CCK Vip (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023019 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023019 "L5/6 cck, VIP GABAergic interneuron (Mmus)")
EquivalentClasses(obo:CL_4023019 ObjectIntersectionOf(obo:CL_4023071 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P32648)))

# Class: obo:CL_4023020 (dynamic gamma motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:13933877") Annotation(oboInOwl:hasDbXref "PMID:139469") Annotation(oboInOwl:hasDbXref "WikipediaVersion:Gamma_motor_neuron&oldid=906640465") obo:IAO_0000115 obo:CL_4023020 "A gamma motor neuron that innervates dynamic nuclear bag fibers (bag1 fibers) and enhances the sensitivities of Ia sensory neurons. They alter muscle spindle sensitivity and increases its discharge in response to velocity of muscle length (rather than just magnitude).")
AnnotationAssertion(terms:contributor obo:CL_4023020 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023020 "dynamic gamma motor neuron")
SubClassOf(obo:CL_4023020 obo:CL_0008037)
SubClassOf(obo:CL_4023020 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_4023005))

# Class: obo:CL_4023021 (static gamma motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:13933877") Annotation(oboInOwl:hasDbXref "PMID:139469") Annotation(oboInOwl:hasDbXref "WikipediaVersion:Gamma_motor_neuron&oldid=906640465") obo:IAO_0000115 obo:CL_4023021 "A gamma motor neuron that innervates static nuclear bag fibers (bag2 fibers) and increases their firing, in response to an increase in the magnitude of change in length, and controls the static sensitivity of the stretch reflex.")
AnnotationAssertion(terms:contributor obo:CL_4023021 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023021 "static gamma motor neuron")
SubClassOf(obo:CL_4023021 obo:CL_0008037)
SubClassOf(obo:CL_4023021 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_4023006))

# Class: obo:CL_4023022 (canopy lamp5 GABAergic cortical interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023022 "canopy lamp5 interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30413647") obo:IAO_0000115 obo:CL_4023022 "A Lamp5 GABAergic cortical interneuron that has extended axons in the surface of L1. Canopy Lamp5 cells resemble neurogliaform cells in having elongated horizontal axonal arbors largely confined to L1; but the dendritic arbors are wider and have fewer branches, while the axon is less tortuous and extends further from the soma")
AnnotationAssertion(terms:contributor obo:CL_4023022 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023022 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023022 "canopy lamp5 GABAergic cortical interneuron (Mmus)")
SubClassOf(obo:CL_4023022 obo:CL_0000099)
SubClassOf(obo:CL_4023022 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023022 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023022 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023022 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q9D387))

# Class: obo:CL_4023023 (L5,6 neurogliaform lamp5 GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023023 "L5,6 NGC Lamp5 interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26727548") obo:IAO_0000115 obo:CL_4023023 "A lamp 5 GABAergic cortical interneuron with neurogliaform morphology with a soma found in L5,6. L5,6 NGC lamp5 have deep afterhyperpolarization (AHP) but narrow action potentials (APs). Unlike other deep neurogliaform cells (which are caudal ganglionic eminence (CGE) derived), L5,6 NGC lamp5 cells are medial ganglionic eminence (MGE)-derived")
AnnotationAssertion(terms:contributor obo:CL_4023023 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023023 "L5,6 NGC Lamp5 (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023023 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023023 "L5,6 neurogliaform lamp5 GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023023 obo:CL_0000099)
SubClassOf(obo:CL_4023023 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070001))
SubClassOf(obo:CL_4023023 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023023 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023023 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023023 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q9D387))

# Class: obo:CL_4023024 (neurogliaform lamp5 GABAergic cortical interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023024 "NGC Lamp5 interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") obo:IAO_0000115 obo:CL_4023024 "A lamp5 GABAergic cortical interneuron with layer-adapting morphology. NGC lamp5 cells have a small round soma, short dendrites, and a wide dense axonal arbor that tends to establish a dense axonal mesh with high connection probability both to themselves and L2 pyramidal cells. NGC lamp5 cells have unique synaptic properties that distinguish them from other GABAergic interneurons, including the release of GABA to the extracellular space via volume transmission, and the ability to produce GABA-B responses in connected postsynaptic targets.")
AnnotationAssertion(terms:contributor obo:CL_4023024 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023024 "NGC Lamp5 (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023024 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023024 "neurogliaform lamp5 GABAergic cortical interneuron (Mmus)")
SubClassOf(obo:CL_4023024 obo:CL_0000099)
SubClassOf(obo:CL_4023024 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070001))
SubClassOf(obo:CL_4023024 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023024 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023024 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023024 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q9D387))

# Class: obo:CL_4023025 (long-range projecting sst GABAergic cortical interneuron (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26727548") obo:IAO_0000115 obo:CL_4023025 "A sst GABAergic cortical interneuron that is both an interneuron and a projecting neuron. They are found in all layers from upper L2/3 down to the bottom of L6. They have long-range projections, some with axons fading into white matter. These cells have low rebound potential, low hyperpolarization sag, and high variability in membrane time constant.")
AnnotationAssertion(terms:contributor obo:CL_4023025 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023025 "LP SST (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023025 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023025 "long-range projecting sst GABAergic cortical interneuron (Mmus)")
SubClassOf(obo:CL_4023025 obo:CL_4023121)
SubClassOf(obo:CL_4023025 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023025 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023025 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023025 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023026 (direct pathway medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2147780") Annotation(oboInOwl:hasDbXref "PMID:215920") Annotation(oboInOwl:hasDbXref "PMID:23354054") Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasDbXref "PMID:36741471") Annotation(oboInOwl:hasDbXref "PMID:9004351") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Medium_spiny_neuron&oldid=1109726850") obo:IAO_0000115 obo:CL_4023026 "A GABAergic medium spiny neuron located in the striatum that gives rise to the direct basal ganglia pathway. It projects directly to the GPi and SNr, where it inhibits tonically active GABAergic output neurons to disinhibit thalamic and brainstem motor targets (Gerfen. 2023). In mice and humans, this cell selectively expresses the D1 dopamine receptor (DRD1), which couples to stimulatory G-proteins (Gs/Gαolf) to increase cAMP and activate PKA-dependent signaling cascades (Gerfen et al., 1990; Kebabian & Calne, 1979). Functionally, activation of this cell promotes selected motor actions by disinhibiting thalamic and midbrain motor centers (Mink, 1996; Cui et al., 2013).")
AnnotationAssertion(terms:contributor obo:CL_4023026 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7258-9596") oboInOwl:hasExactSynonym obo:CL_4023026 "dopamine 1 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023026 "D1-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30096299") Annotation(oboInOwl:hasDbXref "PMID:36741471") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023026 "dSPN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26018615") Annotation(oboInOwl:hasDbXref "PMID:29737578") rdfs:comment obo:CL_4023026 "Despite the direct and indirect circuits are often described not only as functionally opposing but also as anatomically segregated there are several anatomical and functional studies that have challenged this notion of pure segregation based on extensive collateral projections between pathways, dual-projection neurons, simultaneous co-activation during behavior.")
AnnotationAssertion(rdfs:label obo:CL_4023026 "direct pathway medium spiny neuron")
SubClassOf(obo:CL_4023026 obo:CL_1001474)
SubClassOf(obo:CL_4023026 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001175))

# Class: obo:CL_4023027 (L5 sst T-Martinotti interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023027 "L5 T Martinotti sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28254942") Annotation(oboInOwl:hasDbXref "PMID:29326172") obo:IAO_0000115 obo:CL_4023027 "A sst GABAergic cortical interneuron with a soma found in L5 and possesses 'T-shaped' Martinotti morphologies with local axonal plexus in L5a and translaminar axons restricted to the uppermost part of L1. They show low-threshold spiking patterns with strong rebound firing, and inhibit the L1 apical tuft of nearby pyramidal cells.")
AnnotationAssertion(terms:contributor obo:CL_4023027 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023027 "L5 T Martinotti SST (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023027 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023027 "L5 sst T-Martinotti interneuron (Mmus)")
SubClassOf(obo:CL_4023027 obo:CL_0000099)
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070008))
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005394))
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023027 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023028 (L5 non-Martinotti sst GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023028 "L5 non-Martinotti sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28254942") Annotation(oboInOwl:hasDbXref "PMID:29326172") obo:IAO_0000115 obo:CL_4023028 "A sst GABAergic cortical interneuron with a soma found in lower L5 with mostly local axonal arborization but with some sparse ascending axons. L5 non-Martinotti sst cells show somatic localization and local axon plexus in L5b and L5b/6 and substantial innervation of L3 and L4, and receive thalamic input from the ventral posteromedial nucleus and specifically target L4 neurons, avoiding L5 pyramidal cells. L5 non-Martinotti sst cells tend to show a higher input resistance and seem to be less stuttering.")
AnnotationAssertion(terms:contributor obo:CL_4023028 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023028 "L5 non-Martinotti SST (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023028 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023028 "L5 non-Martinotti sst GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023028 obo:CL_0000099)
SubClassOf(obo:CL_4023028 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005394))
SubClassOf(obo:CL_4023028 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023028 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023028 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023029 (indirect pathway medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27453468") Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasDbXref "PMID:36741471") Annotation(oboInOwl:hasDbXref "PMID:9004351") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Medium_spiny_neuron&oldid=1109726850") obo:IAO_0000115 obo:CL_4023029 "A GABAergic medium spiny neuron located in the striatum that gives rise to the indirect basal ganglia pathway. It projects to the GPe, where its axon typically ramifies in two regions but does not extend beyond this nucleus (Gerfen et al., 2022). It selectively expresses the D2 dopamine receptor (DRD2), which couples to inhibitory G-proteins (Gi/o) to decrease cAMP and suppress PKA-mediated signaling (Gerfen et al., 2022). Morphologically, this cell displays fewer and shorter dendrites than the MSN-D1 and receives fewer glutamatergic inputs, yet it exhibits significantly higher intrinsic excitability (Gertler et al., 2022). Functionally, activation of this cell suppresses competing or alternative motor actions by inhibiting GPe neurons, leading through STN and other GPe circuits to increased GPi/SNr output and stronger inhibition of thalamic and brainstem targets (Mink, 1996; Tecuapetla et al., 2016).")
AnnotationAssertion(terms:contributor obo:CL_4023029 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4023029 "D2-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7258-9596") oboInOwl:hasExactSynonym obo:CL_4023029 "dopamine 2 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30096299") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4023029 "iSPN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26018615") Annotation(oboInOwl:hasDbXref "PMID:29737578") rdfs:comment obo:CL_4023029 "Despite the direct and indirect circuits are often described not only as functionally opposing but also as anatomically segregated there are several anatomical and functional studies that have challenged this notion of pure segregation based on extensive collateral projections between pathways, dual-projection neurons, simultaneous co-activation during behavior.")
AnnotationAssertion(rdfs:label obo:CL_4023029 "indirect pathway medium spiny neuron")
SubClassOf(obo:CL_4023029 obo:CL_1001474)
SubClassOf(obo:CL_4023029 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001177))

# Class: obo:CL_4023030 (L2/3/5 fan Martinotti sst GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023030 "L2/3/5 fan Martinotti sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27225074") Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:28254942") Annotation(oboInOwl:hasDbXref "PMID:29326172") obo:IAO_0000115 obo:CL_4023030 "A sst GABAergic cortical interneuron that has \"fanning-out' Martinotti morphology that is found in layer 2/3/5 of the cerebral cortex. They have local axon arbor and long ascending axons that spreads horizontally and arborizes significantly in L1.")
AnnotationAssertion(terms:contributor obo:CL_4023030 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023030 "L2/3/5 fan Martinotti SST (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023030 cl:BDS_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") rdfs:comment obo:CL_4023030 "L2/3/5 fan Martionotti SST cells have an adapting firing pattern and non-zero afterdepolarization (ADP).")
AnnotationAssertion(rdfs:label obo:CL_4023030 "L2/3/5 fan Martinotti sst GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023030 obo:CL_0000099)
SubClassOf(obo:CL_4023030 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070009))
SubClassOf(obo:CL_4023030 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023030 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023030 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023030 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023031 (L4 sst Martinotti interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023031 "L4 sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023031 "A sst GABAergic cortical interneuron with a soma found in lower L2/3 and upper 5, L4 Sst cells have Martinotti morphology with ascending axons but denser local axons and sparser ‘fanning-out’ projections to L1. L4 sst cells have smaller membrane time constant to calb2 (L2/3/5 fan Martinotti Cell) and non-zero afterdepolarization (ADP).")
AnnotationAssertion(terms:contributor obo:CL_4023031 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023031 "L4 SST (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023031 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023031 "L4 sst Martinotti interneuron (Mmus)")
SubClassOf(obo:CL_4023031 obo:CL_0000099)
SubClassOf(obo:CL_4023031 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070007))
SubClassOf(obo:CL_4023031 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005393))
SubClassOf(obo:CL_4023031 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023031 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023032 (ON retinal ganglion cell)

AnnotationAssertion(terms:contributor obo:CL_4023032 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19602302") rdfs:comment obo:CL_4023032 "A retinal ganglion cell that is depolarized by illumination of its receptive field center.")
AnnotationAssertion(rdfs:label obo:CL_4023032 "ON retinal ganglion cell")
SubClassOf(obo:CL_4023032 obo:CL_0000740)

# Class: obo:CL_4023033 (OFF retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19602302") obo:IAO_0000115 obo:CL_4023033 "A retinal ganglion cell that is depolarized by decreased illumination of their receptive field center.")
AnnotationAssertion(terms:contributor obo:CL_4023033 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023033 "OFF retinal ganglion cell")
SubClassOf(obo:CL_4023033 obo:CL_0000740)

# Class: obo:CL_4023034 (obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023034 "OBSOLETE A sst GABAergic cortical interneuron transcriptomically between the sst and the pvalb families with a soma found in L2/3. Some L2/3 PV-like sst cells have Martinotti morphology while some have basket cell morphology. L2/3 PV-like sst cells have lower AP width and higher firing rate than typical Sst subclass cells. L2/3 PV-like sst cells have high maximum firing rate variability, with many classified as belonging to the pvalb subclass on the basis of electrophysiology.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_4023034 <https://github.com/obophenotype/brain_data_standards_ontologies/issues/231>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023034 obo:PCL_1000002)
AnnotationAssertion(terms:contributor obo:CL_4023034 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023034 "L2/3 PV-like SST Mus)")
AnnotationAssertion(rdfs:comment obo:CL_4023034 "Moved to PCL. Use PCL:1000002 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023034 "obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)")
AnnotationAssertion(owl:deprecated obo:CL_4023034 "true"^^xsd:boolean)

# Class: obo:CL_4023035 (lateral ganglionic eminence derived neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "wikipediaversioned:Ganglionic_eminence&oldid=1186824360") obo:IAO_0000115 obo:CL_4023035 "A neuron that is derived from a precursor cell in the lateral ganglion eminence.")
AnnotationAssertion(terms:contributor obo:CL_4023035 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_4023035 "https://orcid.org/0000-0002-7073-9172")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10377350") oboInOwl:hasExactSynonym obo:CL_4023035 "LGE-derived neuron")
AnnotationAssertion(rdfs:label obo:CL_4023035 "lateral ganglionic eminence derived neuron"@en)
EquivalentClasses(obo:CL_4023035 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004025)))
SubClassOf(obo:CL_4023035 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4023036 (pvalb chandelier GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023036 "Pvalb Chandelier")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15378039") Annotation(oboInOwl:hasDbXref "PMID:27199673") Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:37824655") obo:IAO_0000115 obo:CL_4023036 "A transcriptomically distinct pvalb GABAergic interneuron located in the pallium. It is recognizable by the straight terminal axonal 'cartridges' of vertically oriented strings of synaptic boutons. Chandelier PV cells' boutons target exclusively the axon initial segment (AIS) of pyramidal cells, with a single cell innervating hundreds of pyramidal cells in a clustered manner.  These cells are fast-spiking.")
AnnotationAssertion(terms:contributor obo:CL_4023036 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27199673") Annotation(oboInOwl:hasDbXref "PMID:33862423") Annotation(oboInOwl:hasDbXref "PMID:39012795") oboInOwl:hasBroadSynonym obo:CL_4023036 "axo-axonic cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023036 "ILX:0107356")
AnnotationAssertion(Annotation(obo:IAO_0000116 "Interlex cross reference refers specifically to Markram 2015 rat chandelier cell.") oboInOwl:hasDbXref obo:CL_4023036 "ILX:0777213")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023036 "chandelier PV")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023036 "chandelier cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15378039") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023036 "ChC")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023036 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023036 "pvalb chandelier GABAergic interneuron")
SubClassOf(obo:CL_4023036 obo:CL_0000099)
SubClassOf(obo:CL_4023036 obo:CL_4023069)
SubClassOf(obo:CL_4023036 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070011))
SubClassOf(obo:CL_4023036 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000203))
SubClassOf(obo:CL_4023036 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023036 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013502))

# Class: obo:CL_4023038 (L6b glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023038 "L6b glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.34312") Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4023038 "A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate.")
AnnotationAssertion(terms:contributor obo:CL_4023038 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023038 "ILX:0770163")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023038 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023038 "L6b glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023038 ObjectIntersectionOf(obo:CL_0000679 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440003)))

# Class: obo:CL_4023039 (amygdala excitatory neuron)

AnnotationAssertion(terms:contributor obo:CL_4023039 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") rdfs:comment obo:CL_4023039 "An excitatory neuron that is located in the amygdala.")
AnnotationAssertion(rdfs:label obo:CL_4023039 "amygdala excitatory neuron")
EquivalentClasses(obo:CL_4023039 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001876) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535)))

# Class: obo:CL_4023040 (L2/3-6 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023040 "L2/3-6 IT glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4023040 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layers L2/3-6.")
AnnotationAssertion(terms:contributor obo:CL_4023040 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023040 "L2/3-6 IT projecting neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023040 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023040 "L2/3-6 intratelencephalic projecting glutamatergic neuron")
SubClassOf(obo:CL_4023040 obo:CL_4023008)

# Class: obo:CL_4023041 (L5 extratelencephalic projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023041 "L5 ET glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4023041 "A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics.")
AnnotationAssertion(terms:contributor obo:CL_4023041 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.neuron.2005.08.030") oboInOwl:hasBroadSynonym obo:CL_4023041 "subcerebral projection (SCPN) neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31626774") Annotation(rdfs:comment "pyramidal tract-like is used because, unlike pyramidal tract neurons in the motor cortex, neurons in the structures like the auditory cortex do not project to the spinal cord.") oboInOwl:hasExactSynonym obo:CL_4023041 "Pyramidal tract-like (PT-l)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2011.00001") oboInOwl:hasExactSynonym obo:CL_4023041 "burst-firing layer 5 neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2015.00233") oboInOwl:hasExactSynonym obo:CL_4023041 "thick-tufted layer 5 (TTL5) pyramidal neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/nrn3469") oboInOwl:hasNarrowSynonym obo:CL_4023041 "pyramidal tract (PT) neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.neuron.2011.07.029") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023041 "L5b neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023041 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023041 "L5 extratelencephalic projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023041 ObjectIntersectionOf(obo:CL_4023009 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005394)))
SubClassOf(obo:CL_4023041 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070015))

# Class: obo:CL_4023042 (L6 corticothalamic-projecting glutamatergic cortical neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023042 "L6 CT glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4023042 "A transcriptomically distinct corticothalamic-projecting neuron with a soma found in cortical layer 6.")
AnnotationAssertion(terms:contributor obo:CL_4023042 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28625486") Annotation(oboInOwl:hasDbXref "PMID:34616075") oboInOwl:hasExactSynonym obo:CL_4023042 "L6 CT")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023042 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023042 "L6 corticothalamic-projecting glutamatergic cortical neuron")
EquivalentClasses(obo:CL_4023042 ObjectIntersectionOf(obo:CL_4023013 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005395)))
SubClassOf(obo:CL_4023042 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0010225))

# Class: obo:CL_4023043 (L5/6 near-projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023043 "L5/6 NP glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31209381") Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4023043 "A transcriptomically distinct near-projecting glutamatergic neuron with a soma found in layer 5/6 of the primary motor cortex. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', cluster L5/6 NP.")
AnnotationAssertion(terms:contributor obo:CL_4023043 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023043 "ILX:0770161")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023043 "L5/6 NP M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023043 "L5/6 NP MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023043 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023043 "L5/6 near-projecting glutamatergic neuron of the primary motor cortex")
EquivalentClasses(obo:CL_4023043 ObjectIntersectionOf(obo:CL_4030067 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))

# Class: obo:CL_4023044 (non-medulla, extratelencephalic-projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023044 "non-MY ET glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") Annotation(oboInOwl:hasDbXref "PMID:24137110") Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023044 "An extratelencephalic-projecting glutamatergic neuron located in layer 5b of the primary motor cortex that does not project to the medulla. Non-MY ET cells are large, big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting they are corticospinal cells. Non-MY ET cells have bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to L5 IT neurons.")
AnnotationAssertion(terms:contributor obo:CL_4023044 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023044 "non-MY ET M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023044 "non-MY ET MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023044 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023044 "non-medulla, extratelencephalic-projecting glutamatergic neuron of the primary motor cortex")
SubClassOf(obo:CL_4023044 obo:CL_4023041)
SubClassOf(obo:CL_4023044 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))

# Class: obo:CL_4023045 (medulla-projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023045 "MY ET glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") Annotation(oboInOwl:hasDbXref "PMID:24137110") Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023045 "An extratelencephalic-projecting glutamatergic neuron located in layer 5b of the primary motor cortex that projects to the medulla. MY ET cells are large, big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting they are corticospinal cells. MY ET cells have bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to L5 IT neurons.")
AnnotationAssertion(terms:contributor obo:CL_4023045 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023045 "MY ET M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023045 "MY ET MOp")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023045 "medulla-projecting extratelencephalic-projecting glutamatergic neuron of the primary motor cortex")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023045 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023045 "medulla-projecting glutamatergic neuron of the primary motor cortex")
SubClassOf(obo:CL_4023045 obo:CL_4023041)
SubClassOf(obo:CL_4023045 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070031))
SubClassOf(obo:CL_4023045 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023045 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0001896))

# Class: obo:CL_4023046 (L6b glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023046 "L6b subplate glut")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023046 "An excitatory glutamatergic neuron transcriptomically related to the CT subclass, with a soma preferentially located in the bottom of L6 of the primary motor cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023046 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023046 "L6b subplate glutamatergic neuron of the primary motor cortex")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023046 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023046 "L6b glutamatergic neuron of the primary motor cortex")
SubClassOf(obo:CL_4023046 obo:CL_4023038)
SubClassOf(obo:CL_4023046 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))

# Class: obo:CL_4023047 (L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023047 "L2/3 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") obo:IAO_0000115 obo:CL_4023047 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3 of the primary motor cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023047 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") oboInOwl:hasExactSynonym obo:CL_4023047 "L2/3 IT M1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") oboInOwl:hasExactSynonym obo:CL_4023047 "L2/3 IT MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023047 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023047 "L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex")
EquivalentClasses(obo:CL_4023047 ObjectIntersectionOf(obo:CL_4030059 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))

# Class: obo:CL_4023048 (L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023048 "L4/5 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023048 "An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites.")
AnnotationAssertion(terms:contributor obo:CL_4023048 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023048 "ILX:0770174")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023048 "L4/5 IT M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023048 "L4/5 IT MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023048 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023048 "L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex")
EquivalentClasses(obo:CL_4023048 ObjectIntersectionOf(obo:CL_4030062 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))

# Class: obo:CL_4023049 (L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023049 "L5 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023049 "An intratelencephalic-projecting glutamatergic neuron with a soma found in L5 of the primary motor cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023049 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023049 "ILX:0770157")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023049 "L5 IT M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023049 "L5 IT MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023049 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023049 "L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex")
EquivalentClasses(obo:CL_4023049 ObjectIntersectionOf(obo:CL_4030064 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))

# Class: obo:CL_4023050 (L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023050 "L6 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") Annotation(oboInOwl:hasDbXref "PMID:34616063") Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023050 "An intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted.")
AnnotationAssertion(terms:contributor obo:CL_4023050 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023050 "ILX:0770158")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023050 "L6 IT M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023050 "L6 IT MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023050 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023050 "L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex")
EquivalentClasses(obo:CL_4023050 ObjectIntersectionOf(obo:CL_4030065 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384)))
SubClassOf(obo:CL_4023050 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070019))

# Class: obo:CL_4023051 (vascular leptomeningeal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasDbXref "PMID:29443965") Annotation(oboInOwl:hasDbXref "PMID:30096314") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/5346f9c6-755e-4336-94cc-38706ec00c2f.cxg/") obo:IAO_0000115 obo:CL_4023051 "A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC.")
AnnotationAssertion(terms:contributor obo:CL_4023051 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023051 "ILX:0770143")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023051 "VLMC")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023051 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023051 "vascular leptomeningeal cell")
SubClassOf(obo:CL_4023051 obo:CL_4023054)
SubClassOf(obo:CL_4023051 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000391))
SubClassOf(obo:CL_4023051 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0011012))

# Class: obo:CL_4023052 (Betz upper motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") Annotation(oboInOwl:hasDbXref "PMID:18558853") Annotation(oboInOwl:hasDbXref "PMID:28751609") obo:IAO_0000115 obo:CL_4023052 "A Betz cell that synapses with lower motor neurons directly.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4023052 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4023052 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023052 "Betz upper motor neuron")
SubClassOf(obo:CL_4023052 obo:CL_0008049)
SubClassOf(obo:CL_4023052 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0008039))

# Class: obo:CL_4023053 (spinal interneuron synapsing Betz cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") Annotation(oboInOwl:hasDbXref "PMID:18558853") obo:IAO_0000115 obo:CL_4023053 "A Betz cell that syanpses with spinal interneurons.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4023053 obo:NCBITaxon_9685)
AnnotationAssertion(obo:RO_0002175 obo:CL_4023053 obo:NCBITaxon_9989)
AnnotationAssertion(terms:contributor obo:CL_4023053 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023053 "spinal interneuron synapsing Betz cell")
SubClassOf(obo:CL_4023053 obo:CL_0008049)
SubClassOf(obo:CL_4023053 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0005000))

# Class: obo:CL_4023054 (mesothelial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26106328") obo:IAO_0000115 obo:CL_4023054 "A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell.")
AnnotationAssertion(terms:contributor obo:CL_4023054 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023054 "mesothelial fibroblast")
SubClassOf(obo:CL_4023054 obo:CL_0000057)
SubClassOf(obo:CL_4023054 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000077))

# Class: obo:CL_4023055 (corticothalamic VAL/VM projecting glutamatergic neuron of the primary motor cortex)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023055 "CT VAL/VM glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20556241") Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023055 "A corticothalamic-projecting glutamatergic neuron that is located in L6 and lower L5 of the primary motor cortex, with a pyramidal morphology and mostly untufted apical dendrites terminating in midcortical layers. CT VAL/VM (ventroanterior-ventrolateral complex/ventromedial nucleus) cells have a near tonic firing pattern and are distinguished from L6 IT neurons by a lower inter-spike interval adaptation index.")
AnnotationAssertion(terms:contributor obo:CL_4023055 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023055 "CT VAL/VM M1")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023055 "CT VAL/VM MOp")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023055 cl:BDS_subset)
AnnotationAssertion(rdfs:comment obo:CL_4023055 "The assertion of this cell type under L6 CT is due to the ambiguity of lower L5 and L6.")
AnnotationAssertion(rdfs:label obo:CL_4023055 "corticothalamic VAL/VM projecting glutamatergic neuron of the primary motor cortex")
SubClassOf(obo:CL_4023055 obo:CL_4023042)
SubClassOf(obo:CL_4023055 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070019))
SubClassOf(obo:CL_4023055 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))

# Class: obo:CL_4023056 (vascular leptomeningeal cell (Mmus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:IAO_0000115 obo:CL_4023056 "A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain.")
AnnotationAssertion(terms:contributor obo:CL_4023056 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023056 "VLMC (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023056 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023056 "vascular leptomeningeal cell (Mmus)")
SubClassOf(obo:CL_4023056 obo:CL_4023051)
SubClassOf(obo:CL_4023056 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:CL_4023056 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P11087))
SubClassOf(Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:CL_4023056 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P26618))
SubClassOf(Annotation(oboInOwl:hasDbXref "PMID:30096314") obo:CL_4023056 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P51885))

# Class: obo:CL_4023057 (cerebellar inhibitory GABAergic interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023057 "A GABAergic interneuron whose soma is located in the cerebellar cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023057 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023057 "cerebellar inhibitory GABAergic interneuron")
EquivalentClasses(obo:CL_4023057 ObjectIntersectionOf(obo:CL_0011005 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002129)))

# Class: obo:CL_4023058 (mesothelial fibroblast of the leptomeninx)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4023058 "A mesothelial fibroblast found in the leptomeninx.")
AnnotationAssertion(terms:contributor obo:CL_4023058 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023058 "mesothelial fibroblast of the leptomeninx")
EquivalentClasses(obo:CL_4023058 ObjectIntersectionOf(obo:CL_4023054 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000391)))

# Class: obo:CL_4023059 (committed oligodendrocyte precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32066987") obo:IAO_0000115 obo:CL_4023059 "An oligodendrocyte precursor cell that is committed to differentiate.")
AnnotationAssertion(terms:contributor obo:CL_4023059 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4023059 "COP")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023059 "differentiation-committed oligodendrocyte precursor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") rdfs:comment obo:CL_4023059 "COPs are distinct from OPCs in that the lack expression of Pdgfra and Cspg4 and come out as distinct clusters in transcriptomic profiling. This is the reason that this term is not modelled as a subclassOf OPC but instead linked using develops_from.")
AnnotationAssertion(rdfs:label obo:CL_4023059 "committed oligodendrocyte precursor")
SubClassOf(obo:CL_4023059 obo:CL_0000123)
SubClassOf(obo:CL_4023059 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002453))

# Class: obo:CL_4023060 (hippocampal CA1-3 neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023060 "A neuron that has its soma located in CA1-3 of the hippocampus.")
AnnotationAssertion(obo:IAO_0000116 obo:CL_4023060 "It is unclear as to if the modelling of Ammon's horn includes CA4 (which could be considered part of the dentate gyrus) in Uberon, hence no equivalent class axiom was made.")
AnnotationAssertion(terms:contributor obo:CL_4023060 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023060 "hippocampal CA1-3 neuron")
SubClassOf(obo:CL_4023060 obo:CL_0000540)
SubClassOf(obo:CL_4023060 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001954))

# Class: obo:CL_4023061 (hippocampal CA4 neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023061 "A neuron that has its soma located in CA4 of the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_4023061 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023061 "hippocampal CA4 neuron")
SubClassOf(obo:CL_4023061 obo:CL_0000540)
SubClassOf(obo:CL_4023061 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4023062 (dentate gyrus neuron)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4023062 "A neuron with its soma located in the dentate gyrus of the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_4023062 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023062 "dentate gyrus neuron")
EquivalentClasses(obo:CL_4023062 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001885)))

# Class: obo:CL_4023063 (medial ganglionic eminence derived interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023063 "MGE interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023063 "An interneuron that is derived from the medial ganglionic eminence.")
AnnotationAssertion(terms:contributor obo:CL_4023063 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023063 "MGE interneuron")
AnnotationAssertion(rdfs:label obo:CL_4023063 "medial ganglionic eminence derived interneuron")
EquivalentClasses(obo:CL_4023063 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024)))

# Class: obo:CL_4023064 (caudal ganglionic eminence derived interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023064 "CGE interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20130169") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "PMID:37824663") obo:IAO_0000115 obo:CL_4023064 "An interneuron that is derived from the caudal ganglionic eminence.")
AnnotationAssertion(terms:contributor obo:CL_4023064 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20130169") oboInOwl:hasExactSynonym obo:CL_4023064 "caudal ganglionic eminence derived GABAergic interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20130169") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023064 "CGE interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824663") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023064 "CGE interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27034423") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023064 "CGE-derived GABAergic IN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27034423") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023064 "CGE-derived cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20130169") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023064 "CGE-derived interneuron")
AnnotationAssertion(rdfs:label obo:CL_4023064 "caudal ganglionic eminence derived interneuron")
EquivalentClasses(obo:CL_4023064 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026)))
SubClassOf(obo:CL_4023064 obo:CL_4042039)
SubClassOf(obo:CL_4023064 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023064 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_4023065 (meis2 expressing cortical GABAergic cell)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023065 "meis2 GABA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33372656") obo:IAO_0000115 obo:CL_4023065 "A GABAergic cell located in the cerebral cortex that expresses meis2.")
AnnotationAssertion(terms:contributor obo:CL_4023065 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023065 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023065 "meis2 expressing cortical GABAergic cell")
SubClassOf(obo:CL_4023065 obo:CL_0000617)
SubClassOf(obo:CL_4023065 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023065 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000010317))

# Class: obo:CL_4023066 (horizontal pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023066 "A pyramidal neuron which has an apical tree which is oriented parallel to the pia. This is unlike typical pyramidal neurons which have its apical dendrite aligned vertically.")
AnnotationAssertion(terms:contributor obo:CL_4023066 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023066 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023066 "horizontal pyramidal neuron")
EquivalentClasses(obo:CL_4023066 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070016)))

# Class: obo:CL_4023067 (obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023067 "OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has Martinotti morphology.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_4023067 <https://github.com/obophenotype/brain_data_standards_ontologies/issues/231>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023067 obo:PCL_1000004)
AnnotationAssertion(terms:contributor obo:CL_4023067 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023067 "Martinotti L2/3 PV-like SST (Mus)")
AnnotationAssertion(rdfs:comment obo:CL_4023067 "Moved to PCL. Use PCL:1000004 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023067 "obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)")
AnnotationAssertion(owl:deprecated obo:CL_4023067 "true"^^xsd:boolean)

# Class: obo:CL_4023068 (thalamic excitatory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30083593") Annotation(oboInOwl:hasDbXref "PMID:31196673") Annotation(oboInOwl:hasDbXref "PMID:35278647") Annotation(oboInOwl:hasDbXref "PMID:37163009") Annotation(oboInOwl:hasDbXref "PMID:37824663") Annotation(oboInOwl:hasDbXref "PMID:38739251") obo:IAO_0000115 obo:CL_4023068 "An excitatory neuron that has its soma located in the thalamic complex. This neuron type can be involved in a series of circuits related to sensory integration, motor integration, pain processing, social behaviour and reward response.")
AnnotationAssertion(terms:contributor obo:CL_4023068 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11532718") Annotation(oboInOwl:hasDbXref "PMID:30083593") Annotation(oboInOwl:hasDbXref "PMID:38739251") rdfs:comment obo:CL_4023068 "Abnormalities in glutametergic neurons of the thalamic complex are associated with pathologies such as schizophrenia, colorectal visceral pain and Parkinson's disease.")
AnnotationAssertion(rdfs:label obo:CL_4023068 "thalamic excitatory neuron")
EquivalentClasses(obo:CL_4023068 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0010225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535)))

# Class: obo:CL_4023069 (medial ganglionic eminence derived GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023069 "MGE gaba interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12637172") obo:IAO_0000115 obo:CL_4023069 "A GABAergic interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023069 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023069 "medial ganglionic eminence derived GABAergic interneuron")
EquivalentClasses(obo:CL_4023069 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))
SubClassOf(obo:CL_4023069 obo:CL_4023063)

# Class: obo:CL_4023070 (obsolete caudal ganglionic eminence derived GABAergic cortical interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023070 "CGE gaba cortical interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20130169") obo:IAO_0000115 obo:CL_4023070 "OBSOLETE. A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_4023070 <https://github.com/obophenotype/cell-ontology/pull/2374>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023070 obo:CL_4023064)
AnnotationAssertion(terms:contributor obo:CL_4023070 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023070 "CGE cortical interneuron")
AnnotationAssertion(rdfs:comment obo:CL_4023070 "caudal ganglionic eminence derived GABAergic interneuron
and caudal ganglionic eminence derived interneuron are the same cell type. 
The two must be merged and one needs to be defined as obsolete. 
We decided to deprecate the entity with the more specific term and redundant qualities 
in the label. See comments in issue 2357.")
AnnotationAssertion(rdfs:label obo:CL_4023070 "obsolete caudal ganglionic eminence derived GABAergic cortical interneuron")
AnnotationAssertion(owl:deprecated obo:CL_4023070 "true"^^xsd:boolean)

# Class: obo:CL_4023071 (L5/6 cck GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023071 "L5/6 cck interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023071 "A GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization.")
AnnotationAssertion(terms:contributor obo:CL_4023071 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023071 "L5/6 CCK (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023071 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023071 "L5/6 cck GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023071 obo:CL_0000099)
SubClassOf(obo:CL_4023071 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440002))
SubClassOf(obo:CL_4023071 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023071 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023071 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P09240))

# Class: obo:CL_4023072 (brain vascular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023072 "A cell that is part of the brain vasculature.")
AnnotationAssertion(terms:contributor obo:CL_4023072 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023072 "brain vascular cell")
EquivalentClasses(obo:CL_4023072 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008998)))

# Class: obo:CL_4023073 (obsolete choroid plexus cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023073 "OBSOLETE. A cell that is part of the choroid plexus.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_4023073 <https://github.com/obophenotype/cell-ontology/issues/2043>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023073 obo:CL_0000706)
AnnotationAssertion(terms:contributor obo:CL_4023073 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023073 "obsolete choroid plexus cell")
AnnotationAssertion(owl:deprecated obo:CL_4023073 "true"^^xsd:boolean)

# Class: obo:CL_4023074 (mammillary body neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023074 "A neuron that has its soma located in the mammillary body.")
AnnotationAssertion(terms:contributor obo:CL_4023074 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023074 "mammillary body neuron")
EquivalentClasses(obo:CL_4023074 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002206)))

# Class: obo:CL_4023075 (L6 th sst GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023075 "L6 th sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22357664") obo:IAO_0000115 obo:CL_4023075 "A sst GABAergic cortical interneuron found in L6 that expresses tyrosine hydroxylase. L6 Th+ SST cells have mostly local axonal arborization within L6.")
AnnotationAssertion(terms:contributor obo:CL_4023075 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023075 "L6 Th+ SST (Mus musculus)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023075 "L6 tyrosine hydroxylase positive sst expressing GABAergic cortical interneuron (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023075 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023075 "L6 th sst GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023075 obo:CL_0000099)
SubClassOf(obo:CL_4023075 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005395))
SubClassOf(obo:CL_4023075 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023075 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023075 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P24529))
SubClassOf(obo:CL_4023075 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023076 (Martinotti neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Martinotti_cell&oldid=9947732") obo:IAO_0000115 obo:CL_4023076 "An interneuron that has Martinotti morphology. These interneurons are scattered throughout various layers of the cerebral cortex, sending their axons up to the cortical layer I where they form axonal arborization.")
AnnotationAssertion(terms:contributor obo:CL_4023076 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023076 "ILX:0107375")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023076 "NIFEXT:55")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023076 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023076 "Martinotti neuron")
EquivalentClasses(obo:CL_4023076 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070007) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023077 (bitufted neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18568015") obo:IAO_0000115 obo:CL_4023077 "A type of interneuron that has two clusters of dendritic branches that originate directly from the soma and extend in opposite directions and axons that form a plexus which spreads widely. Compared to bipolar neurons, bitufted neurons have branching that occur close to the soma.")
AnnotationAssertion(terms:contributor obo:CL_4023077 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(obo:IAO_0000116 "Interlex cross reference refers specifically to Markram 2015 rat bitufted cell.") oboInOwl:hasDbXref obo:CL_4023077 "ILX:0777212")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023077 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023077 "bitufted neuron")
EquivalentClasses(obo:CL_4023077 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070012)))

# Class: obo:CL_4023078 (obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023078 "OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has basket morphology.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_4023078 <https://github.com/obophenotype/brain_data_standards_ontologies/issues/231>)
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023078 obo:PCL_1000003)
AnnotationAssertion(terms:contributor obo:CL_4023078 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023078 "basket L2/3 PV-like SST (Mus)")
AnnotationAssertion(rdfs:comment obo:CL_4023078 "Moved to PCL. Use PCL:1000003 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023078 "obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)")
AnnotationAssertion(owl:deprecated obo:CL_4023078 "true"^^xsd:boolean)

# Class: obo:CL_4023079 (midbrain-derived inhibitory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4023079 "A GABAergic inhibitory neuron that is derived from the midbrain.")
AnnotationAssertion(terms:contributor obo:CL_4023079 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023079 "midbrain-derived inhibitory neuron")
EquivalentClasses(obo:CL_4023079 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0001891)))
SubClassOf(obo:CL_4023079 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4023080 (stellate L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023080 "stellate L6 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023080 "a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has stellate pyramidal morphology.")
AnnotationAssertion(terms:contributor obo:CL_4023080 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023080 "stellate L6 IT MOp (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023080 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023080 "stellate L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus)")
SubClassOf(obo:CL_4023080 obo:CL_4023050)
SubClassOf(obo:CL_4023080 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070020))

# Class: obo:CL_4023081 (inverted L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023081 "inverted L6 IT glut MOp")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023081 "a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has inverted pyramidal morphology.")
AnnotationAssertion(terms:contributor obo:CL_4023081 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023081 "inverted L6 IT MOp (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023081 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023081 "inverted L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus)")
SubClassOf(obo:CL_4023081 obo:CL_4023050)
SubClassOf(obo:CL_4023081 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070021))

# Class: obo:CL_4023083 (obsolete chandelier cell)

AnnotationAssertion(obo:IAO_0100001 obo:CL_4023083 obo:CL_4023036)
AnnotationAssertion(rdfs:comment obo:CL_4023083 "Duplicate term")
AnnotationAssertion(rdfs:label obo:CL_4023083 "obsolete chandelier cell")
AnnotationAssertion(owl:deprecated obo:CL_4023083 "true"^^xsd:boolean)

# Class: obo:CL_4023086 (T Martinotti neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/b978-0-12-369497-3.10004-4") obo:IAO_0000115 obo:CL_4023086 "A Martinotti neuron that has axons that form a horizontal ramification, making it T-shaped.")
AnnotationAssertion(terms:contributor obo:CL_4023086 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023086 "T-shaped Martinotti neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023086 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023086 "T Martinotti neuron")
EquivalentClasses(obo:CL_4023086 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070008) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023087 (fan Martinotti neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/b978-0-12-369497-3.10004-4") obo:IAO_0000115 obo:CL_4023087 "A Martinotti neuron that has axons that form a fan-like plexus.")
AnnotationAssertion(terms:contributor obo:CL_4023087 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023087 "fanning-out Martinotti neuron")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023087 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023087 "fan Martinotti neuron")
EquivalentClasses(obo:CL_4023087 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070009) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023088 (large basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11884355") obo:IAO_0000115 obo:CL_4023088 "A basket cell that is large, and typically ascends to give rise to many long horizontally and vertically projecting axon collaterals that traverse neighboring columns and can extend through all cortical layers.")
AnnotationAssertion(terms:contributor obo:CL_4023088 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023088 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023088 "large basket cell")
EquivalentClasses(obo:CL_4023088 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070004) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001950) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023089 (nest basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11884355") obo:IAO_0000115 obo:CL_4023089 "A basket cell which has simpler dendritic arbors (compared to small or large basket cells), and an axonal plexus of intermediate density, composed of a few long, smooth axonal branches.")
AnnotationAssertion(terms:contributor obo:CL_4023089 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023089 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023089 "nest basket cell")
EquivalentClasses(obo:CL_4023089 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070005) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001950) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023090 (small basket cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11884355") obo:IAO_0000115 obo:CL_4023090 "A basket cell with axonal arbors composed of frequent, short, curvy axonal branches that tend to be near their somata and within the same layer.")
AnnotationAssertion(terms:contributor obo:CL_4023090 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023090 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023090 "small basket cell")
EquivalentClasses(obo:CL_4023090 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070003) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001950) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4023092 (inverted pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023092 "A pyramidal neuron which has an apical tree which is oriented towards the white matter.")
AnnotationAssertion(terms:contributor obo:CL_4023092 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023092 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023092 "inverted pyramidal neuron")
EquivalentClasses(obo:CL_4023092 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070021)))

# Class: obo:CL_4023093 (stellate pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023093 "A pyramidal neuron which lacks a tuft formation but extends small radial distances forming a star-like shape.")
AnnotationAssertion(terms:contributor obo:CL_4023093 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023093 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023093 "stellate pyramidal neuron")
EquivalentClasses(obo:CL_4023093 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070020)))

# Class: obo:CL_4023094 (tufted pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023094 "A pyramidal neuron which has a distinctive tuft formation, distal from the soma.")
AnnotationAssertion(terms:contributor obo:CL_4023094 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023094 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023094 "tufted pyramidal neuron")
EquivalentClasses(obo:CL_4023094 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070018)))

# Class: obo:CL_4023095 (untufted pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023095 "A pyramidal neuron which lacks a clear tuft formation but extends to large radial distances.")
AnnotationAssertion(terms:contributor obo:CL_4023095 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023095 cl:BDS_subset)
AnnotationAssertion(rdfs:label obo:CL_4023095 "untufted pyramidal neuron")
EquivalentClasses(obo:CL_4023095 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070019)))

# Class: obo:CL_4023097 (arachnoid barrier cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23298861") obo:IAO_0000115 obo:CL_4023097 "A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura.")
AnnotationAssertion(terms:contributor obo:CL_4023097 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23298861") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023097 "AB cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30096314") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023097 "ABC")
AnnotationAssertion(rdfs:label obo:CL_4023097 "arachnoid barrier cell")
SubClassOf(obo:CL_4023097 obo:CL_4023054)
SubClassOf(obo:CL_4023097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000437))

# Class: obo:CL_4023098 (obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023098 "OBSOLETE An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 2/3 of the human primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023098 obo:CL_4023047)
AnnotationAssertion(terms:contributor obo:CL_4023098 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023098 "L2/3 IT MOp (human)")
AnnotationAssertion(rdfs:comment obo:CL_4023098 "Made terms species agnostic, use CL:4023047 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023098 "obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens)")
AnnotationAssertion(owl:deprecated obo:CL_4023098 "true"^^xsd:boolean)

# Class: obo:CL_4023099 (obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023099 "OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the human primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023099 obo:CL_4023049)
AnnotationAssertion(terms:contributor obo:CL_4023099 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023099 "ILX:0770157")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023099 "L5 IT MOp (human)")
AnnotationAssertion(rdfs:comment obo:CL_4023099 "Made terms species agnostic, use CL:4023049 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023099 "obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens)")
AnnotationAssertion(owl:deprecated obo:CL_4023099 "true"^^xsd:boolean)

# Class: obo:CL_4023100 (obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023100 "OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the human primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023100 obo:CL_4023050)
AnnotationAssertion(terms:contributor obo:CL_4023100 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023100 "ILX:0770158")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023100 "L6 IT MOp (human)")
AnnotationAssertion(rdfs:comment obo:CL_4023100 "Made terms species agnostic, use CL:4023050 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023100 "obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens)")
AnnotationAssertion(owl:deprecated obo:CL_4023100 "true"^^xsd:boolean)

# Class: obo:CL_4023101 (obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023101 "OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the human primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023101 obo:CL_4023043)
AnnotationAssertion(terms:contributor obo:CL_4023101 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023101 "ILX:0770161")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023101 "L5/6 NP MOp (human)")
AnnotationAssertion(rdfs:comment obo:CL_4023101 "Made terms species agnostic, use CL:4023043 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023101 "obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Homo sapiens)")
AnnotationAssertion(owl:deprecated obo:CL_4023101 "true"^^xsd:boolean)

# Class: obo:CL_4023102 (obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023102 "OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the marmoset primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023102 obo:CL_4023043)
AnnotationAssertion(terms:contributor obo:CL_4023102 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023102 "ILX:0770161")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023102 "L5/6 NP MOp (marmoset)")
AnnotationAssertion(rdfs:comment obo:CL_4023102 "Made terms species agnostic, use CL:4023043 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023102 "obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus)")
AnnotationAssertion(owl:deprecated obo:CL_4023102 "true"^^xsd:boolean)

# Class: obo:CL_4023103 (obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023103 "OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 2/3 of the marmoset primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023103 obo:CL_4023047)
AnnotationAssertion(terms:contributor obo:CL_4023103 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023103 "L2/3 IT MOp (marmoset)")
AnnotationAssertion(rdfs:comment obo:CL_4023103 "Made terms species agnostic, use CL:4023047 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023103 "obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus)")
AnnotationAssertion(owl:deprecated obo:CL_4023103 "true"^^xsd:boolean)

# Class: obo:CL_4023104 (obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023104 "OBSOLETE An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the marmoset primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023104 obo:CL_4023049)
AnnotationAssertion(terms:contributor obo:CL_4023104 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023104 "ILX:0770157")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023104 "L5 IT MOp (marmoset)")
AnnotationAssertion(rdfs:comment obo:CL_4023104 "Made terms species agnostic, use CL:4023049 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023104 "obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus)")
AnnotationAssertion(owl:deprecated obo:CL_4023104 "true"^^xsd:boolean)

# Class: obo:CL_4023105 (obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023105 "OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the marmoset primary motor cortex.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023105 obo:CL_4023050)
AnnotationAssertion(terms:contributor obo:CL_4023105 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023105 "ILX:0770158")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023105 "L6 IT MOp (marmoset)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023105 cl:BDS_subset)
AnnotationAssertion(rdfs:comment obo:CL_4023105 "Made terms species agnostic, use CL:4023050 instead.")
AnnotationAssertion(rdfs:label obo:CL_4023105 "obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus)")
AnnotationAssertion(owl:deprecated obo:CL_4023105 "true"^^xsd:boolean)

# Class: obo:CL_4023106 (obsolete meis2 expressing cortical GABAergic cell (Callithrix jacchus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.03.31.016972") obo:IAO_0000115 obo:CL_4023106 "OBSOLETE. A mouse GABAergic cell located in the marmoset cerebral cortex that expresses meis2.")
AnnotationAssertion(obo:IAO_0100001 obo:CL_4023106 obo:CL_4023065)
AnnotationAssertion(terms:contributor obo:CL_4023106 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023106 "Meis2 (Marmoset)")
AnnotationAssertion(rdfs:comment obo:CL_4023106 "false"^^xsd:boolean)
AnnotationAssertion(rdfs:label obo:CL_4023106 "obsolete meis2 expressing cortical GABAergic cell (Callithrix jacchus)")
AnnotationAssertion(owl:deprecated obo:CL_4023106 "true"^^xsd:boolean)

# Class: obo:CL_4023107 (reticulospinal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29720934") obo:IAO_0000115 obo:CL_4023107 "A neuron with soma location in the reticular formation with axons that extend into the spinal cord such. Reticulospinal neuron activity can lead to a variety of motor behaviors.")
AnnotationAssertion(terms:contributor obo:CL_4023107 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29720934") oboInOwl:hasExactSynonym obo:CL_4023107 "RSN")
AnnotationAssertion(rdfs:label obo:CL_4023107 "reticulospinal neuron")
EquivalentClasses(obo:CL_4023107 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002275) ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0002240)))

# Class: obo:CL_4023108 (oxytocin-secreting magnocellular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Magnocellular_neurosecretory_cell&oldid=1021059931") obo:IAO_0000115 obo:CL_4023108 "A magnocellular neurosecretory cell that is capable of producing and secreting oxytocin.")
AnnotationAssertion(terms:contributor obo:CL_4023108 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023108 "oxytocin-secreting magnocellular cell")
EquivalentClasses(obo:CL_4023108 ObjectIntersectionOf(obo:CL_0011003 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036162)))

# Class: obo:CL_4023109 (vasopressin-secreting magnocellular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Magnocellular_neurosecretory_cell&oldid=1021059931") obo:IAO_0000115 obo:CL_4023109 "A magnocellular neurosecretory cell that is capable of producing and secreting vasopressin.")
AnnotationAssertion(terms:contributor obo:CL_4023109 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023109 "vasopressin-secreting magnocellular cell")
EquivalentClasses(obo:CL_4023109 ObjectIntersectionOf(obo:CL_0011003 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030103)))

# Class: obo:CL_4023110 (amygdala pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1375860") obo:IAO_0000115 obo:CL_4023110 "A pyramidal neuron with soma located in the amygdala.")
AnnotationAssertion(terms:contributor obo:CL_4023110 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023110 "amygdala pyramidal neuron")
EquivalentClasses(obo:CL_4023110 ObjectIntersectionOf(obo:CL_0000598 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001876)))

# Class: obo:CL_4023111 (cerebral cortex pyramidal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30715238") obo:IAO_0000115 obo:CL_4023111 "A pyramidal neuron with soma located in the cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023111 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023111 "cerebral cortex pyramidal neuron")
EquivalentClasses(obo:CL_4023111 ObjectIntersectionOf(obo:CL_0000598 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956)))

# Class: obo:CL_4023112 (vestibular afferent neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2585041") obo:IAO_0000115 obo:CL_4023112 "An afferent neuron of the vestibular system that innervate the base of the hair cell and increase or decrease their neural firing rate as the receptor cell is excited or inhibited.")
AnnotationAssertion(terms:contributor obo:CL_4023112 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023112 "vestibular afferent neuron")
SubClassOf(obo:CL_4023112 obo:CL_0000101)
SubClassOf(obo:CL_4023112 ObjectSomeValuesFrom(obo:RO_0002120 obo:CL_0000609))

# Class: obo:CL_4023113 (bouton vestibular afferent neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10706428") obo:IAO_0000115 obo:CL_4023113 "A vestibular afferent neuron that makes bouton synapses to type II hair cells.")
AnnotationAssertion(terms:contributor obo:CL_4023113 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023113 "bouton vestibular afferent neuron")
SubClassOf(obo:CL_4023113 obo:CL_4023112)
SubClassOf(obo:CL_4023113 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043195))
SubClassOf(obo:CL_4023113 ObjectSomeValuesFrom(obo:RO_0002130 obo:CL_0002069))

# Class: obo:CL_4023114 (calyx vestibular afferent neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25355208") obo:IAO_0000115 obo:CL_4023114 "A vestibular afferent neuron which posseses a unique postsynaptic terminal, the calyx, which completely covers the basolateral walls of type I hair cells and receives input from multiple ribbon synapses.")
AnnotationAssertion(terms:contributor obo:CL_4023114 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023114 "calyx vestibular afferent neuron")
SubClassOf(obo:CL_4023114 obo:CL_4023112)
SubClassOf(obo:CL_4023114 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0099096))
SubClassOf(obo:CL_4023114 ObjectSomeValuesFrom(obo:RO_0002130 obo:CL_0002070))

# Class: obo:CL_4023115 (type 1 spiral ganglion neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Spiral_ganglion&oldid=994446209") obo:IAO_0000115 obo:CL_4023115 "A spiral ganglion neuron that innervates inner hair cells. Type 1 spiral ganglion neurons are myelinated and bipolar.")
AnnotationAssertion(terms:contributor obo:CL_4023115 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023115 "type I spiral ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Spiral_ganglion&oldid=994446209") rdfs:comment obo:CL_4023115 "Type 1 spiral ganglion neurons comprise the vast majority of spiral ganglion cells.")
AnnotationAssertion(rdfs:label obo:CL_4023115 "type 1 spiral ganglion neuron")
EquivalentClasses(obo:CL_4023115 ObjectIntersectionOf(obo:CL_0011113 ObjectSomeValuesFrom(obo:RO_0002134 obo:CL_0000589)))
SubClassOf(obo:CL_4023115 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070006))

# Class: obo:CL_4023116 (type 2 spiral ganglion neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Spiral_ganglion&oldid=994446209") obo:IAO_0000115 obo:CL_4023116 "A spiral ganglion neuron that innervates outer hair cells. Type 1 spiral ganglion neurons are unmyelinated and unipolar.")
AnnotationAssertion(terms:contributor obo:CL_4023116 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023116 "type II spiral ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Spiral_ganglion&oldid=994446209") rdfs:comment obo:CL_4023116 "Outer hair cells form reciprocal synapses onto type 2 spiral ganglion cells, suggesting that the type 2 cells have both afferent and efferent roles.")
AnnotationAssertion(rdfs:label obo:CL_4023116 "type 2 spiral ganglion neuron")
EquivalentClasses(obo:CL_4023116 ObjectIntersectionOf(obo:CL_0011113 ObjectSomeValuesFrom(obo:RO_0002134 obo:CL_0000601)))
SubClassOf(obo:CL_4023116 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070025))

# Class: obo:CL_4023118 (L5/6 non-Martinotti sst GABAergic interneuron (Mmus))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023118 "L5/6 non-Martinotti sst interneuron (Mus)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") obo:IAO_0000115 obo:CL_4023118 "A sst GABAergic interneuron does not have Martinotti morphology with a soma found in L5/6 of the cerebral cortex.")
AnnotationAssertion(terms:contributor obo:CL_4023118 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023118 "L5/6 non-Martinotti SST (Mus musculus)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023118 "L5/6 non-Martinotti morphology sst expressing GABAergic cortical interneuron (Mus musculus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023118 cl:BDS_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") rdfs:comment obo:CL_4023118 "L5/6 non-Martinotti SST cells have strongly facilitating excitatory inputs and moderately depressing outputs. They have faster action potential than Martinotti morphology SST cells and slightly slower than PV basket cells.")
AnnotationAssertion(rdfs:label obo:CL_4023118 "L5/6 non-Martinotti sst GABAergic interneuron (Mmus)")
SubClassOf(obo:CL_4023118 obo:CL_0000099)
SubClassOf(obo:CL_4023118 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440002))
SubClassOf(obo:CL_4023118 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))
SubClassOf(obo:CL_4023118 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023118 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P60041))

# Class: obo:CL_4023119 (displaced amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21557506") Annotation(oboInOwl:hasDbXref "PMID:67960") obo:IAO_0000115 obo:CL_4023119 "A subpopulation of amacrine cell that migrate further than other amacrine cells, and come to lie basal to the inner plexiform layer (IPL) in the ganglion cell layer. Displaced amacrine cells still have their neurites extending apically into the IPL, and therefore exhibit an inverted polarity with respect to the other amacrine cells.")
AnnotationAssertion(terms:contributor obo:CL_4023119 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023119 "dACs")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023119 "inverted amacrine cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18719084") rdfs:comment obo:CL_4023119 "Displaced amacrine cells are a subset of Sox2 expressing amacrine cells.")
AnnotationAssertion(rdfs:label obo:CL_4023119 "displaced amacrine cell")
SubClassOf(obo:CL_4023119 obo:CL_0000561)
SubClassOf(obo:CL_4023119 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015426))

# Class: obo:CL_4023120 (cochlea auditory hair cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Hair_cell") obo:IAO_0000115 obo:CL_4023120 "An auditory hair cell found in the cochlea.")
AnnotationAssertion(terms:contributor obo:CL_4023120 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023120 "FMA:62364")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023120 "cochlear hair cell")
AnnotationAssertion(rdfs:label obo:CL_4023120 "cochlea auditory hair cell")
EquivalentClasses(obo:CL_4023120 ObjectIntersectionOf(obo:CL_0000202 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002227)))

# Class: obo:CL_4023121 (sst chodl GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4023121 "sst chodl interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15845086") Annotation(oboInOwl:hasDbXref "PMID:31209381") Annotation(oboInOwl:hasDbXref "PMID:33372656") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4023121 "A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection.")
AnnotationAssertion(terms:contributor obo:CL_4023121 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33372656") oboInOwl:hasBroadSynonym obo:CL_4023121 "long-range GABAergic interneuron")
AnnotationAssertion(rdfs:label obo:CL_4023121 "sst chodl GABAergic interneuron")
SubClassOf(obo:CL_4023121 obo:CL_0000099)
SubClassOf(obo:CL_4023121 obo:CL_4023069)
SubClassOf(obo:CL_4023121 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023121 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024))
SubClassOf(obo:CL_4023121 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023121 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000005444))
SubClassOf(obo:CL_4023121 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015665))

# Class: obo:CL_4023122 (oxytocin receptor sst GABAergic cortical interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25303526") obo:IAO_0000115 obo:CL_4023122 "An interneuron located in the cerebral cortex that expresses the oxytocin receptor. These interneurons also express somatostatin.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25303526") obo:RO_0002175 obo:CL_4023122 obo:NCBITaxon_10090)
AnnotationAssertion(terms:contributor obo:CL_4023122 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25303526") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023122 "OxtrINs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25303526") rdfs:comment obo:CL_4023122 "These cells were first identified in mouse.")
AnnotationAssertion(rdfs:label obo:CL_4023122 "oxytocin receptor sst GABAergic cortical interneuron")
SubClassOf(obo:CL_4023122 obo:CL_0000099)
SubClassOf(obo:CL_4023122 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4023122 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023122 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001635))
SubClassOf(obo:CL_4023122 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015665))

# Class: obo:CL_4023123 (hypothalamus kisspeptin neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30042117") obo:IAO_0000115 obo:CL_4023123 "A kisspeptin neuron that is located in the hypothalamus. These neurons project to and activate gonadotrophin-releasing hormone neurons (acting via the kisspeptin receptor) in the hypothalamus and stimulate the secretion of gonadotrophin-releasing hormone.")
AnnotationAssertion(terms:contributor obo:CL_4023123 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023123 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(rdfs:label obo:CL_4023123 "hypothalamus kisspeptin neuron")
EquivalentClasses(obo:CL_4023123 ObjectIntersectionOf(obo:CL_4023130 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001898)))

# Class: obo:CL_4023124 (dentate gyrus kisspeptin neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Kisspeptin&oldid=1042853037") obo:IAO_0000115 obo:CL_4023124 "A kisspeptin neuron that is located in the dentate gyrus of the hippocampus.")
AnnotationAssertion(terms:contributor obo:CL_4023124 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023124 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(rdfs:label obo:CL_4023124 "dentate gyrus kisspeptin neuron")
EquivalentClasses(obo:CL_4023124 ObjectIntersectionOf(obo:CL_4023130 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001885)))

# Class: obo:CL_4023125 (KNDy neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:KNDy_neuron&oldid=964682278") obo:IAO_0000115 obo:CL_4023125 "A hypothalamus kisspeptin neuron that coexpresses kisspeptin, neurokinin B and dynorphin.")
AnnotationAssertion(terms:contributor obo:CL_4023125 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023125 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023125 "kisspeptin, neurokinin B and dynorphin expressing neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:KNDy_neuron&oldid=964682278") rdfs:comment obo:CL_4023125 "KNDy neurons are involved in the negative feedback of gonadotropin-releasing hormone release in the hypothalamic–pituitary–gonadal axis. Sex steroids released from the gonads act on KNDy neurons as inhibitors of kisspeptin release. This inhibition provides negative feedback control on the hypothalamic–pituitary–gonadal axis. Other roles of KNDy neurons include influences on prolactin production; puberty; stress' effects on reproduction; and the control of thermoregulation.")
AnnotationAssertion(rdfs:label obo:CL_4023125 "KNDy neuron")
EquivalentClasses(obo:CL_4023125 ObjectIntersectionOf(obo:CL_4023123 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000012526) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000016004)))

# Class: obo:CL_4023127 (arcuate nucleus of hypothalamus KNDy neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30042117") obo:IAO_0000115 obo:CL_4023127 "a KNDy neuron that is located in the arcuate nucleus of the hypothalamus.")
AnnotationAssertion(terms:contributor obo:CL_4023127 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023127 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(rdfs:label obo:CL_4023127 "arcuate nucleus of hypothalamus KNDy neuron")
EquivalentClasses(obo:CL_4023127 ObjectIntersectionOf(obo:CL_4023125 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001932)))

# Class: obo:CL_4023128 (rostral periventricular region of the third ventricle KNDy neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30042117") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:KNDy_neuron&oldid=964682278") obo:IAO_0000115 obo:CL_4023128 "a KNDy neuron that is located in the rostral periventricular region of the third ventricle.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Anteroventral_periventricular_nucleus&oldid=966137187") obo:IAO_0000116 obo:CL_4023128 "In rats and mice, the anteroventral periventricular nucleus plus the periventricular nucleus make up the rostral periventricular region of the third ventricle (RP3V).")
AnnotationAssertion(terms:contributor obo:CL_4023128 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023128 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023128 "RP3V KNDy neuron")
AnnotationAssertion(rdfs:label obo:CL_4023128 "rostral periventricular region of the third ventricle KNDy neuron")
EquivalentClasses(obo:CL_4023128 ObjectIntersectionOf(obo:CL_4023125 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440005)))

# Class: obo:CL_4023129 (retinoblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17565741") obo:IAO_0000115 obo:CL_4023129 "A retinal cell that is immature or undifferentiated.")
AnnotationAssertion(terms:contributor obo:CL_4023129 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023129 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17565741") oboInOwl:hasExactSynonym obo:CL_4023129 "retinal stem cell")
AnnotationAssertion(rdfs:label obo:CL_4023129 "retinoblast")
SubClassOf(obo:CL_4023129 obo:CL_0009004)
SubClassOf(obo:CL_4023129 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966))

# Class: obo:CL_4023130 (kisspeptin neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30042117") obo:IAO_0000115 obo:CL_4023130 "A neuron that expresses kisspeptin. These neurons are predominantly located in the hypothalamus, but also found in other parts of the brain including the hippocampal dentate gyrus.")
AnnotationAssertion(terms:contributor obo:CL_4023130 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(terms:contributor obo:CL_4023130 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30042117") rdfs:comment obo:CL_4023130 "Gonadal sex steroids stimulate kisspeptin neurons in the RP3V, but inhibit kisspeptin neurons in the ARC.")
AnnotationAssertion(rdfs:label obo:CL_4023130 "kisspeptin neuron")
EquivalentClasses(obo:CL_4023130 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000009344)))
SubClassOf(obo:CL_4023130 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4023154 (myelinating glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1007/3-540-29623-9_3240") obo:IAO_0000115 obo:CL_4023154 "A glial cell that myelinates axonal processes.")
AnnotationAssertion(terms:contributor obo:CL_4023154 <https://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023154 "myelinating glial cell")
EquivalentClasses(obo:CL_4023154 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043209)))

# Class: obo:CL_4023158 (octopus cell of the mammalian cochlear nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:title=Cochlear_nucleus&oldid=1090176664") obo:IAO_0000115 obo:CL_4023158 "A neuron in the posterior ventral cochlear nucleus that is distinguished by their long, thick and tentacle-shaped dendrites that typically emanate from one side of the cell body.")
AnnotationAssertion(obo:IAO_0000116 obo:CL_4023158 "This term is restricted to the mammalian cochlear nucleus to disambiguate for cells of octopus.")
AnnotationAssertion(terms:contributor obo:CL_4023158 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11976365") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:title=Cochlear_nucleus&oldid=1090176664") rdfs:comment obo:CL_4023158 "Octopus cells respond only at the onset of a broad-band simple tonal stimulus and form a pathway to the superior paraolivary nucleus and to the ventral nucleus of the lateral lemniscus.")
AnnotationAssertion(rdfs:label obo:CL_4023158 "octopus cell of the mammalian cochlear nucleus")
SubClassOf(obo:CL_4023158 obo:CL_0000540)
SubClassOf(obo:CL_4023158 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002831))
SubClassOf(obo:CL_4023158 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_8440043))

# Class: obo:CL_4023159 (double bouquet cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15378039") obo:IAO_0000115 obo:CL_4023159 "An interneuron that has double bouquet morphology.")
AnnotationAssertion(terms:contributor obo:CL_4023159 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023159 "double bouquet cell")
EquivalentClasses(obo:CL_4023159 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070061)))

# Class: obo:CL_4023160 (cartwheel cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ILX:0102311") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Cartwheel_cell&oldid=1040398094") obo:IAO_0000115 obo:CL_4023160 "A neuron of the dorsal cochlear nucleus with spiny dendrites that receive input from the axons of granule cells and with axons that release GABA and glycine onto cartwheel, pyramidal and giant cell targets.")
AnnotationAssertion(terms:contributor obo:CL_4023160 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023160 "ILX:0102311")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ILX:0102311") rdfs:comment obo:CL_4023160 "Cartwheel cells share many of the features, molecular and electrophysiological, of cerebellar Purkinje neurons.")
AnnotationAssertion(rdfs:label obo:CL_4023160 "cartwheel cell")
SubClassOf(obo:CL_4023160 obo:CL_0000540)
SubClassOf(obo:CL_4023160 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002829))
SubClassOf(obo:CL_4023160 ObjectSomeValuesFrom(obo:RO_0002103 obo:CL_0000120))
SubClassOf(obo:CL_4023160 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4023160 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537))

# Class: obo:CL_4023161 (unipolar brush cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9193142") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Unipolar_brush_cell&oldid=1045937026") obo:IAO_0000115 obo:CL_4023161 "An excitatory glutamatergic interneuron found in the granular layer of the cerebellar cortex and also in the granule cell domain of the cochlear nucleus. Unipolar brush cells have a round or oval cell body with usually a single short dendrite that ends in a brush-like tuft of short dendrites unique to them known as dendrioles.")
AnnotationAssertion(terms:contributor obo:CL_4023161 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023161 "neuronal brush cell")
AnnotationAssertion(rdfs:label obo:CL_4023161 "unipolar brush cell")
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cnp.2022.11.002") foaf:depiction obo:CL_4023161 <http://purl.obolibrary.org/obo/cl/images/CB_circuits_PMID3650468_f2.png>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_4023161 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
SubClassOf(obo:CL_4023161 obo:CL_0000099)
SubClassOf(obo:CL_4023161 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0044293))
SubClassOf(obo:CL_4023161 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070025))
SubClassOf(obo:CL_4023161 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002028))
SubClassOf(obo:CL_4023161 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535))

# Class: obo:CL_4023162 (bushy cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Bushy_cell&oldid=879061753") obo:IAO_0000115 obo:CL_4023162 "A neuron found in the anterior part of the ventral cochlear nucleus that has the appearance of bushes, having short dendrites. Bushy cells give outputs to different parts of the superior olivary complex.")
AnnotationAssertion(terms:contributor obo:CL_4023162 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023162 "bushy cell")
SubClassOf(obo:CL_4023162 obo:CL_0000540)
SubClassOf(obo:CL_4023162 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002830))
SubClassOf(obo:CL_4023162 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0002128))

# Class: obo:CL_4023163 (spherical bushy cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31881018") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Bushy_cell&oldid=879061753") obo:IAO_0000115 obo:CL_4023163 "A bushy cell that receives only few large excitatory endbulb synapses from auditory nerves. Spherical bush cells give excitatory input to the lateral and medial parts of the superior olive.")
AnnotationAssertion(terms:contributor obo:CL_4023163 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31881018") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4023163 "SBC")
AnnotationAssertion(rdfs:label obo:CL_4023163 "spherical bushy cell")
SubClassOf(obo:CL_4023163 obo:CL_4023162)

# Class: obo:CL_4023164 (globular bushy cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31881018") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Bushy_cell&oldid=879061753") obo:IAO_0000115 obo:CL_4023164 "A bushy cell that receives a large number of medium-sized synapses, called modified endbulbs. Globular bushy cells extend to the superior olive on both sides of the brainstem where they give input to the bipolar neurons.")
AnnotationAssertion(terms:contributor obo:CL_4023164 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31881018") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4023164 "GBC")
AnnotationAssertion(rdfs:label obo:CL_4023164 "globular bushy cell")
SubClassOf(obo:CL_4023164 obo:CL_4023162)

# Class: obo:CL_4023168 (somatosensory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22865660") obo:IAO_0000115 obo:CL_4023168 "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli.")
AnnotationAssertion(terms:contributor obo:CL_4023168 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023168 "somatosensory neuron")
EquivalentClasses(obo:CL_4023168 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003942) ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000010)))

# Class: obo:CL_4023169 (trigeminal neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22190641") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Trigeminal_nerve&oldid=1099897926") obo:IAO_0000115 obo:CL_4023169 "A neuron that is responsible for sensation in the face or motor functions such as biting and chewing. Trigeminal neurons extend a single axon shaft along the lateral white matter of the hindbrain and spinal cord. The highly branched axons innervate the integument of the head.")
AnnotationAssertion(terms:contributor obo:CL_4023169 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023169 "trigeminal neuron")
SubClassOf(obo:CL_4023169 obo:CL_0000540)
SubClassOf(obo:CL_4023169 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4023170 (trigeminal sensory neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK539823/") obo:IAO_0000115 obo:CL_4023170 "A trigeminal neuron that is responsible for sensation in the face.")
AnnotationAssertion(terms:contributor obo:CL_4023170 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023170 "trigeminal sensory neuron")
EquivalentClasses(obo:CL_4023170 ObjectIntersectionOf(obo:CL_4023169 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050906)))
SubClassOf(obo:CL_4023170 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003942))

# Class: obo:CL_4023171 (trigeminal motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK539823/") obo:IAO_0000115 obo:CL_4023171 "A trigeminal neuron that is responsible for motor functions such as biting and chewing.")
AnnotationAssertion(terms:contributor obo:CL_4023171 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(rdfs:label obo:CL_4023171 "trigeminal motor neuron")
EquivalentClasses(obo:CL_4023171 ObjectIntersectionOf(obo:CL_0000100 obo:CL_4023169))

# Class: obo:CL_4023181 (hypendymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-7258-9596>) Annotation(oboInOwl:hasDbXref "PMID:26778959") Annotation(oboInOwl:hasDbXref "PMID:9579598") obo:IAO_0000115 obo:CL_4023181 "A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin.")
AnnotationAssertion(terms:contributor obo:CL_4023181 <http://orcid.org/0000-0002-2105-0715>)
AnnotationAssertion(rdfs:label obo:CL_4023181 "hypendymal cell")
SubClassOf(obo:CL_4023181 obo:CL_0000710)
SubClassOf(obo:CL_4023181 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002139))
SubClassOf(obo:CL_4023181 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015658))

# Class: obo:CL_4023187 (koniocellular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Lateral_geniculate_nucleus&oldid=1098375993") obo:IAO_0000115 obo:CL_4023187 "A neuron with a small cell body that is located in a koniocellular layer of the lateral geniculate nucleus (LGN).")
AnnotationAssertion(terms:contributor obo:CL_4023187 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023187 "NIFEXT:44")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10845061") oboInOwl:hasExactSynonym obo:CL_4023187 "K cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10845061") rdfs:comment obo:CL_4023187 "In adult monkeys, koniocellular cells can be distinguished from parvocellular and magnocellular of the LGN by their expression of calbindin, the alpha subunit of type II calmodulin-dependent protein kinase, and the gamma subunit of protein kinase C.")
AnnotationAssertion(rdfs:label obo:CL_4023187 "koniocellular cell")
EquivalentClasses(obo:CL_4023187 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0013615)))

# Class: obo:CL_4023188 (midget ganglion cell of retina)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32533915") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Midget_cell&oldid=982299713") obo:IAO_0000115 obo:CL_4023188 "A retinal ganglion cell that originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies.")
AnnotationAssertion(terms:contributor obo:CL_4023188 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_4023188 "https://orcid.org/0000-0001-7655-4833")
AnnotationAssertion(rdfs:comment obo:CL_4023188 "There are midget bipolar cells of retina and midget ganglion cells of retina and they are not the same:
Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances from the fovea (retinal eccentricity of 4.5mm as compared to 12 mm). Midget ganglion cells (MGC) have larger dendritic fields (here seen at 8 mm) as they increase in eccentricity.")
AnnotationAssertion(rdfs:label obo:CL_4023188 "midget ganglion cell of retina")
SubClassOf(obo:CL_4023188 obo:CL_0000740)
SubClassOf(obo:CL_4023188 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0013607))

# Class: obo:CL_4023189 (parasol ganglion cell of retina)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32533915") Annotation(oboInOwl:hasDbXref "WikipediaVersioned:Parasol_cell&oldid=1032171532") obo:IAO_0000115 obo:CL_4023189 "A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields.")
AnnotationAssertion(terms:contributor obo:CL_4023189 "https://orcid.org/0000-0001-7258-9596")
AnnotationAssertion(terms:contributor obo:CL_4023189 "https://orcid.org/0000-0001-7655-4833")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_4023189 "M cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_4023189 "M ganglion cell")
AnnotationAssertion(rdfs:comment obo:CL_4023189 "These cells should not be confused with M1-M14 retinal ganglion cells described in PMID:16626866 which refer to a different classification of retinal ganglion cells.")
AnnotationAssertion(rdfs:label obo:CL_4023189 "parasol ganglion cell of retina")
SubClassOf(obo:CL_4023189 obo:CL_0000740)
SubClassOf(obo:CL_4023189 ObjectSomeValuesFrom(obo:RO_0013001 obo:UBERON_0013606))

# Class: obo:CL_4028001 (pulmonary capillary endothelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4028001 "Any capillary endothelial cell that is part of a lung.")
AnnotationAssertion(terms:contributor obo:CL_4028001 <https://orcid.org/0000-0002-3293-5463>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4028001 "2021-11-23T02:31:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4028001 "lung capillary endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4028001 "pulmonary capillary endothelial cell")
EquivalentClasses(obo:CL_4028001 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
SubClassOf(obo:CL_4028001 obo:CL_2000016)
SubClassOf(obo:CL_4028001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0016405))

# Class: obo:CL_4028002 (alveolar capillary type 1 endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31233341") Annotation(oboInOwl:hasDbXref "PMID:32059772") Annotation(oboInOwl:hasDbXref "PMID:32059779") Annotation(oboInOwl:hasDbXref "PMID:32091393") Annotation(oboInOwl:hasDbXref "PMID:33057196") Annotation(oboInOwl:hasDbXref "PMID:33705684") obo:IAO_0000115 obo:CL_4028002 "An alveolar capillary endothelial cell that is located distally to alveolar capillary type 2 endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_4028002 <https://orcid.org/0000-0002-3293-5463>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4028002 "2021-11-23T03:23:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028002 "capillary 1 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33057196") oboInOwl:hasBroadSynonym obo:CL_4028002 "general capillary cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028002 "CAP1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33057196") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028002 "gCAP")
AnnotationAssertion(rdfs:label obo:CL_4028002 "alveolar capillary type 1 endothelial cell")
SubClassOf(obo:CL_4028002 obo:CL_4028001)
SubClassOf(obo:CL_4028002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002299))

# Class: obo:CL_4028003 (alveolar capillary type 2 endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31233341") Annotation(oboInOwl:hasDbXref "PMID:32059772") Annotation(oboInOwl:hasDbXref "PMID:32059779") Annotation(oboInOwl:hasDbXref "PMID:32091393") Annotation(oboInOwl:hasDbXref "PMID:33057196") obo:IAO_0000115 obo:CL_4028003 "An alveolar capillary endothelial cell that is located proximally to alveolar capillary type 1 endothelial cells and in close apposition to alveolar type 1 epithelial cells (also known as type I pneumocytes).")
AnnotationAssertion(terms:contributor obo:CL_4028003 <https://orcid.org/0000-0002-3293-5463>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4028003 "2021-11-23T03:23:53Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028003 "CD34hi endothelial cells")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028003 "Car4+ capillary endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33057196") oboInOwl:hasBroadSynonym obo:CL_4028003 "aerocyte")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028003 "alveolar capillary cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028003 "capillary 2 cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028003 "aCAP")
AnnotationAssertion(rdfs:label obo:CL_4028003 "alveolar capillary type 2 endothelial cell")
SubClassOf(obo:CL_4028003 obo:CL_4028001)
SubClassOf(obo:CL_4028003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002299))

# Class: obo:CL_4028004 (alveolar type 1 fibroblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22268140") Annotation(oboInOwl:hasDbXref "PMID:26706109") Annotation(oboInOwl:hasDbXref "PMID:28886382") Annotation(oboInOwl:hasDbXref "PMID:29489752") Annotation(oboInOwl:hasDbXref "PMID:30675802") Annotation(oboInOwl:hasDbXref "PMID:33624948") Annotation(oboInOwl:hasDbXref "PMID:33707239") Annotation(oboInOwl:hasDbXref "PMID:9074756") obo:IAO_0000115 obo:CL_4028004 "A pulmonary interstitial fibroblast that is part of the alveolus and contains lipid droplets.")
AnnotationAssertion(terms:contributor obo:CL_4028004 <https://orcid.org/0000-0001-9610-7627>)
AnnotationAssertion(terms:contributor obo:CL_4028004 <https://orcid.org/0000-0002-1425-877X>)
AnnotationAssertion(terms:contributor obo:CL_4028004 <https://orcid.org/0000-0002-3293-5463>)
AnnotationAssertion(terms:contributor obo:CL_4028004 <https://orcid.org/0000-0002-8445-4565>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4028004 "2021-12-09T15:34:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "alveolar fibroblast")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "alveolar fibroblast 1")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "lipid interstitial cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "lipofibroblast")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "matrix fibroblast 1")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028004 "pulmonary lipofibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028004 "AF1")
AnnotationAssertion(rdfs:label obo:CL_4028004 "alveolar type 1 fibroblast cell")
SubClassOf(obo:CL_4028004 obo:CL_0002241)
SubClassOf(obo:CL_4028004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002299))

# Class: obo:CL_4028006 (alveolar adventitial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26706109") Annotation(oboInOwl:hasDbXref "PMID:28886382") Annotation(oboInOwl:hasDbXref "PMID:29752282") Annotation(oboInOwl:hasDbXref "PMID:30675802") Annotation(oboInOwl:hasDbXref "PMID:33208946") Annotation(oboInOwl:hasDbXref "PMID:33624948") obo:IAO_0000115 obo:CL_4028006 "A pulmonary interstitial fibroblast that is part of the alveolus and localizes to vascular adventitia.")
AnnotationAssertion(terms:contributor obo:CL_4028006 <https://orcid.org/0000-0002-3293-5463>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4028006 "2021-12-09T15:53:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028006 "adventitial fibroblast")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028006 "alveolar fibroblast")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028006 "matrix fibroblast 2")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028006 "mesenchymal alveolar niche cell")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4028006 "type-2 associated stromal cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4028006 "alveolar type 2 fibroblast cell")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028006 "AF2")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33208946") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028006 "AdvF")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4028006 "MANC")
AnnotationAssertion(rdfs:label obo:CL_4028006 "alveolar adventitial fibroblast")
SubClassOf(obo:CL_4028006 obo:CL_0002241)
SubClassOf(obo:CL_4028006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002299))

# Class: obo:CL_4029001 (gamete-nursing cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/bs.ctdb.2020.10.008") obo:IAO_0000115 obo:CL_4029001 "A cell that supports the development of a gamete by providing it cytoplasmic material (including entire organelles) by direct cross-membrane channels (del Pino, 2021).")
AnnotationAssertion(terms:contributor obo:CL_4029001 <http://orcid.org/0000-0002-6095-8718>)
AnnotationAssertion(terms:date obo:CL_4029001 "2022-06-08T15:29:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4029001 "BTO:0000953")
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_4029001 "cell")
AnnotationAssertion(rdfs:label obo:CL_4029001 "gamete-nursing cell")
SubClassOf(obo:CL_4029001 obo:CL_0000000)

# Class: obo:CL_4029002 (germline-derived nurse cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/bs.ctdb.2020.10.008") obo:IAO_0000115 obo:CL_4029002 "A gamete-nursing cell that derives from a germline cell (del Pino, 2021).")
AnnotationAssertion(terms:contributor obo:CL_4029002 <http://orcid.org/0000-0002-6095-8718>)
AnnotationAssertion(terms:date obo:CL_4029002 "2022-06-08T15:32:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_4029002 "cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1126/science.aad2156") rdfs:comment obo:CL_4029002 "Nurse cells were first described in insects, but recent works suggest they also exist in some mammals (Lei and Spradling, 2016).")
AnnotationAssertion(rdfs:label obo:CL_4029002 "germline-derived nurse cell")
SubClassOf(obo:CL_4029002 obo:CL_0000039)
SubClassOf(obo:CL_4029002 obo:CL_4029001)

# Class: obo:CL_4029003 (somatic nurse-like cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/bs.ctdb.2020.10.008") obo:IAO_0000115 obo:CL_4029003 "A gamete-nursing cell that derives from the somatic tissues of the gonad (del Pino, 2021).")
AnnotationAssertion(terms:contributor obo:CL_4029003 <http://orcid.org/0000-0002-6095-8718>)
AnnotationAssertion(terms:date obo:CL_4029003 "2022-06-08T15:38:03Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasOBONamespace obo:CL_4029003 "cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1111/andr.12165") rdfs:comment obo:CL_4029003 "We follow what seems to be a common usage in the literature, which is to reserve the term “nurse cell” proper to cells from the germ line, hence the label “nurse-like”. This term encompasses pyriform cells described in reptiles, bird, and amphibians (del Pino, 2021); it does not encompass mammalian Sertoli cells, which do not appear to transfer cytoplasmic material to spermatogonia (França et al., 2016).")
AnnotationAssertion(rdfs:label obo:CL_4029003 "somatic nurse-like cell")
SubClassOf(obo:CL_4029003 obo:CL_4029001)

# Class: obo:CL_4030000 (choroidal melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31819095") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0002-0819-0473") obo:IAO_0000115 obo:CL_4030000 "A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses.")
AnnotationAssertion(oboInOwl:creation_date obo:CL_4030000 "2022-01-20T12:59:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030000 "uveal melanocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31819095") Annotation(oboInOwl:hasDbXref "PMID:34082079") rdfs:comment obo:CL_4030000 "Cellular functions and extracellular interactions of choroidal melanocytes are distinct to skin melanocytes. They might have both neuroectodermal as well as mesectodermal origins.")
AnnotationAssertion(rdfs:label obo:CL_4030000 "choroidal melanocyte")
EquivalentClasses(obo:CL_4030000 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001768)))

# Class: obo:CL_4030001 (stromal cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-020-20082-7") obo:IAO_0000115 obo:CL_4030001 "A stromal cell that is part of the thymus.")
AnnotationAssertion(terms:date obo:CL_4030001 "2022-07-08T11:39:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030001 "thymic stromal cell")
AnnotationAssertion(rdfs:label obo:CL_4030001 "stromal cell of thymus")
EquivalentClasses(obo:CL_4030001 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370)))

# Class: obo:CL_4030002 (effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2825-0621") obo:IAO_0000115 obo:CL_4030002 "An alpha-beta memory T cell with the phenotype CD45RA-positive.")
AnnotationAssertion(oboInOwl:creation_date obo:CL_4030002 "2022-02-01T13:04:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16237082") oboInOwl:hasBroadSynonym obo:CL_4030002 "TEMRA")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16237082") oboInOwl:hasBroadSynonym obo:CL_4030002 "effector memory RA T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25104859") oboInOwl:hasExactSynonym obo:CL_4030002 "TEMRA cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25104859") oboInOwl:hasExactSynonym obo:CL_4030002 "terminally differentiated effector memory CD45RA+ T cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/T_cell#Memory_T_cells") oboInOwl:hasExactSynonym obo:CL_4030002 "terminally differentiated effector memory cells re-expressing CD45RA")
AnnotationAssertion(rdfs:label obo:CL_4030002 "effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated")
SubClassOf(obo:CL_4030002 obo:CL_0000791)

# Class: obo:CL_4030003 (interstitial cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-020-20082-7") obo:IAO_0000115 obo:CL_4030003 "A cell that makes up the loose connective tissue of the thymus.")
AnnotationAssertion(terms:date obo:CL_4030003 "2022-07-08T11:48:36Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030003 "thymic interstitial cell")
AnnotationAssertion(rdfs:label obo:CL_4030003 "interstitial cell of thymus")
SubClassOf(obo:CL_4030003 obo:CL_4030001)

# Class: obo:CL_4030004 (thymic nurse cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/Thymic_nurse_cell") obo:IAO_0000115 obo:CL_4030004 "A large epithelial cell found in the thymus. This cell type may internalize thymocytes through extensions of plasma membrane. The cell surface and cytoplasmic vacuoles of a thymic nurse cell express MHC Class I and MHC Class II antigens. The interaction of these antigens with a developing thymocyte determines whether the thymocyte undergoes positive or negative selection.")
AnnotationAssertion(terms:contributor obo:CL_4030004 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4030004 "2022-02-18T12:43:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030004 "thymic nurse cell")
SubClassOf(obo:CL_4030004 obo:CL_0002293)

# Class: obo:CL_4030005 (kidney collecting duct beta-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24051376") Annotation(oboInOwl:hasDbXref "PMID:31300091") Annotation(oboInOwl:hasDbXref "PMID:32016094") obo:IAO_0000115 obo:CL_4030005 "A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type.")
AnnotationAssertion(terms:date obo:CL_4030005 "2022-09-14T16:19:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32016094") oboInOwl:hasExactSynonym obo:CL_4030005 "B-IC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31300091") oboInOwl:hasExactSynonym obo:CL_4030005 "kidney collecting duct intercalated cell type B")
AnnotationAssertion(rdfs:label obo:CL_4030005 "kidney collecting duct beta-intercalated cell")
EquivalentClasses(obo:CL_4030005 ObjectIntersectionOf(obo:CL_0002201 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004203)))

# Class: obo:CL_4030006 (fallopian tube secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1186/1477-7827-7-129") Annotation(oboInOwl:hasDbXref "https://doi.org/10.3390/cells8080933") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/learn/dictionary/normal/fallopian+tube") obo:IAO_0000115 obo:CL_4030006 "An epithelial cell that is part of the fallopian tube that secretes mucus and oviduct-specific products in response to hormonal stimulation from estrogen and luteinizing hormone. This fallopian tube secretory cell is similar in height to the ciliated cell, but typically exhibits a more narrow, columnar shape. Its nucleus is ovoid and oriented perpendicular to the cell's long axis, with denser chromatin and a smaller nucleolus compared to the ciliated cell.")
AnnotationAssertion(terms:contributor obo:CL_4030006 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4030006 "2022-03-03T10:39:31Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030006 "oviduct secretory epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030006 "uterine tube secretory epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.ccr.2013.10.013") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/learn/dictionary/normal/fallopian+tube") rdfs:comment obo:CL_4030006 "The other cell types of the fallopian tube epithelium include the ciliated cell and the intercalary cell, or peg cell. The fallopian tube secretory epithelial cell type has been implicated as a source of high-grade serous ovarian carcinoma.")
AnnotationAssertion(rdfs:label obo:CL_4030006 "fallopian tube secretory epithelial cell")
SubClassOf(obo:CL_4030006 obo:CL_1001591)
SubClassOf(obo:CL_4030006 obo:CL_4052019)
SubClassOf(obo:CL_4030006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889))

# Class: obo:CL_4030007 (fallopian tube multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16565155") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/humanproteome/tissue/fallopian+tube") obo:IAO_0000115 obo:CL_4030007 "A multi-ciliated epithelial cell that is part of the fallopian tube, mainly found on the apex of the mucosal folds. This cell exhibits a columnar shape with an oval nucleus and is characterized by the presence of cilia on its surface. The coordinated beating of these cilia, together with peristaltic contractions, contributes to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube.")
AnnotationAssertion(terms:contributor obo:CL_4030007 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4030007 "2022-03-08T12:40:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030007 "oviduct ciliated cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030007 "fallopian tube ciliated cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030007 "fallopian tube multiciliated cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030007 "uterine tube ciliated epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4030007 "fallopian tube multiciliated epithelial cell")
SubClassOf(obo:CL_4030007 obo:CL_0005012)
SubClassOf(obo:CL_4030007 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889))
SubClassOf(obo:CL_4030007 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007589))

# Class: obo:CL_4030008 (pronephric podocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10322630") obo:IAO_0000115 obo:CL_4030008 "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the pronephros.")
AnnotationAssertion(terms:contributor obo:CL_4030008 <https://orcid.org/0000-0002-2244-7917>)
AnnotationAssertion(terms:date obo:CL_4030008 "2022-03-11T14:38:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0001673") oboInOwl:hasExactSynonym obo:CL_4030008 "pronephric glomerular visceral epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4030008 "pronephric podocyte")
EquivalentClasses(obo:CL_4030008 ObjectIntersectionOf(obo:CL_0000653 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002120)))
SubClassOf(obo:CL_4030008 obo:CL_0000653)

# Class: obo:CL_4030009 (epithelial cell of proximal tubule segment 1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:23897681") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030009 "A brush border cell that is part of segment 1 (S1) of the proximal tubule epithelium, located in the renal cortex.")
AnnotationAssertion(terms:date obo:CL_4030009 "2022-05-10T13:14:00Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030009 "epithelial cell of segment 1 of proximal tubule")
AnnotationAssertion(rdfs:label obo:CL_4030009 "epithelial cell of proximal tubule segment 1")
EquivalentClasses(obo:CL_4030009 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004196) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(obo:CL_4030009 obo:CL_0002307)

# Class: obo:CL_4030010 (epithelial cell of proximal tubule segment 2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:23897681") Annotation(oboInOwl:hasDbXref "PMID:31249312") Annotation(oboInOwl:hasDbXref "PMID:31253652") obo:IAO_0000115 obo:CL_4030010 "A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium, located in the renal cortex. In addition to its reabsorptive functions, it is also specialized in the secretion of organic anions and cations, including para-aminohippurate.")
AnnotationAssertion(terms:date obo:CL_4030010 "2022-05-10T13:26:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030010 "epithelial cell of segment 2 of proximal tubule")
AnnotationAssertion(rdfs:label obo:CL_4030010 "epithelial cell of proximal tubule segment 2")
EquivalentClasses(obo:CL_4030010 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004197) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(obo:CL_4030010 obo:CL_0002307)

# Class: obo:CL_4030011 (epithelial cell of proximal tubule segment 3)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030011 "A brush border cell that is part of segment 3 (S3) of the proximal tubule epithelium, which extends from the medullary rays of the renal cortex into the outer medulla.")
AnnotationAssertion(terms:date obo:CL_4030011 "2022-05-10T13:31:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030011 "epithelial cell of segment 3 of proximal tubule")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") rdfs:comment obo:CL_4030011 "The epithelial cell of proximal tubule segment 3 operates under relatively hypoxic conditions and is particularly susceptible to ischemic injury.")
AnnotationAssertion(rdfs:label obo:CL_4030011 "epithelial cell of proximal tubule segment 3")
EquivalentClasses(obo:CL_4030011 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001290) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
SubClassOf(obo:CL_4030011 obo:CL_0002307)

# Class: obo:CL_4030012 (kidney loop of Henle short descending thin limb epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33769951") obo:IAO_0000115 obo:CL_4030012 "Epithelial cell of the descending thin limb of the short loop (cortical) nephron limited to the outer medulla (mainly inner strip). It is known in some mammalian species that the short descending limb of the loop of Henle selectively expresses the serine protease Corin, the homeobox TF Uncx, and the urea channel Slc14a2.")
AnnotationAssertion(terms:contributor obo:CL_4030012 <https://orcid.org/0000-0003-2804-127X>)
AnnotationAssertion(terms:date obo:CL_4030012 "2022-05-13T11:00:29Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030012 "epithelial cell of the descending thin limb of the short loop of Henle")
AnnotationAssertion(rdfs:label obo:CL_4030012 "kidney loop of Henle short descending thin limb epithelial cell")
EquivalentClasses(obo:CL_4030012 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005099)))
SubClassOf(obo:CL_4030012 obo:CL_0000076)
SubClassOf(obo:CL_4030012 obo:CL_1001111)

# Class: obo:CL_4030013 (kidney loop of Henle long descending thin limb outer medulla epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0003-2804-127X>) Annotation(oboInOwl:hasDbXref "PMID:33769951") obo:IAO_0000115 obo:CL_4030013 "Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the outer medulla (inner stripe). It is known in some mammalian species that the long descending limb of the loop of Henle in the outer medulla selectively expresses the secreted activin-antagonist protein follistatin (Fst), the GPI-linked adhesion protein Cdh13, and the protein kinase Stk32a.")
AnnotationAssertion(terms:date obo:CL_4030013 "2022-05-13T11:11:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030013 "epithelial cell of the outer medulla of the long descending limb of the loop of Henle")
AnnotationAssertion(rdfs:label obo:CL_4030013 "kidney loop of Henle long descending thin limb outer medulla epithelial cell")
SubClassOf(obo:CL_4030013 obo:CL_1001111)
SubClassOf(obo:CL_4030013 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005100))

# Class: obo:CL_4030014 (kidney loop of Henle long descending thin limb inner medulla epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0003-2804-127X>) Annotation(oboInOwl:hasDbXref "PMID:33769951") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/gene/8170") obo:IAO_0000115 obo:CL_4030014 "Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the inner medulla. It is known in some mammalian species that the long descending limb of the loop of Henle in the inner medulla selectively expresses the nuclear receptor Nr2e3, the Ig kappa chain Igkc, and the secreted protein dermokine (Dmkn). SLC14A2, which expresses a urea transporter, is also expressed in the inner medulla.")
AnnotationAssertion(terms:date obo:CL_4030014 "2022-05-13T11:16:54Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030014 "epithelial cell of the inner medulla of the long descending limb of the loop of Henle")
AnnotationAssertion(rdfs:label obo:CL_4030014 "kidney loop of Henle long descending thin limb inner medulla epithelial cell")
SubClassOf(obo:CL_4030014 obo:CL_1001111)
SubClassOf(obo:CL_4030014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005100))

# Class: obo:CL_4030015 (kidney collecting duct alpha-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030015 "A renal alpha-intercalated cell that is part of the collecting duct of the renal tubule.")
AnnotationAssertion(terms:contributor obo:CL_4030015 <https://orcid.org/0000-0003-2804-127X>)
AnnotationAssertion(terms:date obo:CL_4030015 "2022-05-31T11:15:10Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030015 "kidney collecting duct intercalated cell type A")
AnnotationAssertion(rdfs:label obo:CL_4030015 "kidney collecting duct alpha-intercalated cell")
EquivalentClasses(obo:CL_4030015 ObjectIntersectionOf(obo:CL_0005011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001232)))

# Class: obo:CL_4030016 (epithelial cell of early distal convoluted tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0003-2804-127X>) Annotation(oboInOwl:hasDbXref "PMID:24855283") obo:IAO_0000115 obo:CL_4030016 "An epithelial cell located in the early distal convoluted tubule.")
AnnotationAssertion(terms:date obo:CL_4030016 "2022-06-21T12:47:48Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") oboInOwl:hasBroadSynonym obo:CL_4030016 "DCT1 cell")
AnnotationAssertion(rdfs:label obo:CL_4030016 "epithelial cell of early distal convoluted tubule")
EquivalentClasses(obo:CL_4030016 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005101)))

# Class: obo:CL_4030017 (epithelial cell of late distal convoluted tubule)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0003-2804-127X>) Annotation(oboInOwl:hasDbXref "PMID:24855283") obo:IAO_0000115 obo:CL_4030017 "An epithelial cell located in the late distal convoluted tubule.")
AnnotationAssertion(terms:date obo:CL_4030017 "2022-06-21T13:51:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") oboInOwl:hasBroadSynonym obo:CL_4030017 "DCT2 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") rdfs:comment obo:CL_4030017 "Although mineralocorticoid receptors are expressed throughout the entire [distal convoluted tubule], the DCT2 is sensitive to the actions of aldosterone, because it expresses an enzyme called 11-β hydroxysteroid dehydrogenase 2 (11-βHSD2)")
AnnotationAssertion(rdfs:label obo:CL_4030017 "epithelial cell of late distal convoluted tubule")
EquivalentClasses(obo:CL_4030017 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005102)))

# Class: obo:CL_4030018 (kidney connecting tubule principal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <http://orcid.org/0000-0003-2804-127X>) Annotation(oboInOwl:hasDbXref "PMID:27582101") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030018 "A renal principal cell located in the connecting tubule.")
AnnotationAssertion(terms:date obo:CL_4030018 "2022-06-27T15:25:10Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030018 "kidney connecting tubule principal cell")
EquivalentClasses(obo:CL_4030018 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097)))
SubClassOf(obo:CL_4030018 obo:CL_1000768)

# Class: obo:CL_4030019 (kidney connecting tubule intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030019 "A renal intercalated cell that is part of the renal connecting tubule.")
AnnotationAssertion(terms:date obo:CL_4030019 "2022-06-29T11:25:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030019 "kidney connecting tubule intercalated cell")
EquivalentClasses(obo:CL_4030019 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097)))
SubClassOf(obo:CL_4030019 obo:CL_1000768)

# Class: obo:CL_4030020 (kidney connecting tubule alpha-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2254448") Annotation(oboInOwl:hasDbXref "PMID:24937428") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030020 "A renal alpha-intercalated cell that is part of the renal connecting tubule.")
AnnotationAssertion(terms:date obo:CL_4030020 "2022-06-29T12:48:43Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24937428") oboInOwl:hasExactSynonym obo:CL_4030020 "connecting tubule A-IC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030020 "kidney connecting tubule intercalated cell type A")
AnnotationAssertion(rdfs:label obo:CL_4030020 "kidney connecting tubule alpha-intercalated cell")
EquivalentClasses(obo:CL_4030020 ObjectIntersectionOf(obo:CL_0005011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097)))

# Class: obo:CL_4030021 (kidney connecting tubule beta-intercalated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2254448") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030021 "A renal beta-intercalated cell that is part of the renal connecting tubule.")
AnnotationAssertion(terms:date obo:CL_4030021 "2022-06-29T14:31:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32065116") oboInOwl:hasExactSynonym obo:CL_4030021 "connecting tubule B-IC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030021 "kidney connecting tubule intercalated cell type B")
AnnotationAssertion(rdfs:label obo:CL_4030021 "kidney connecting tubule beta-intercalated cell")
EquivalentClasses(obo:CL_4030021 ObjectIntersectionOf(obo:CL_0002201 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097)))

# Class: obo:CL_4030022 (renal medullary fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://doi.org/10.1101/2021.07.28.454201>) Annotation(oboInOwl:hasDbXref "PMID:10559635") obo:IAO_0000115 obo:CL_4030022 "A fibroblast that is located in the renal medulla interstitium.")
AnnotationAssertion(terms:date obo:CL_4030022 "2022-07-05T12:13:40Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030022 "kidney medullary fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10559635") rdfs:comment obo:CL_4030022 "It has been noted that inner medullary fibroblasts are involved in the regulation of water and electrolyte homeostasis.")
AnnotationAssertion(rdfs:label obo:CL_4030022 "renal medullary fibroblast")
EquivalentClasses(obo:CL_4030022 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005211)))

# Class: obo:CL_4030023 (respiratory tract hillock cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-7772-9578>) Annotation(oboInOwl:hasDbXref "PMID:30069044") Annotation(oboInOwl:hasDbXref "PMID:32726565") Annotation(oboInOwl:hasDbXref "PMID:33442032") obo:IAO_0000115 obo:CL_4030023 "A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation.")
AnnotationAssertion(terms:date obo:CL_4030023 "2022-06-06T08:31:09Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030023 "hillock cell of respiratory tract")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030023 "respiratory hillock cell")
AnnotationAssertion(rdfs:label obo:CL_4030023 "respiratory tract hillock cell")
EquivalentClasses(obo:CL_4030023 ObjectIntersectionOf(obo:CL_4030024 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802)))

# Class: obo:CL_4030024 (hillock cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30069044") obo:IAO_0000115 obo:CL_4030024 "An epithelial, transitional cell type between basal and secretory; located in stratified, non-ciliated structures (called hillocks) with high cell turnover in epithelium. In some mammalian species, this cell type has been noted to express KRT13 and is postulated to play a role in squamous barrier function and immunomodulation.")
AnnotationAssertion(terms:date obo:CL_4030024 "2022-06-24T14:52:24Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030024 "hillock cell")
SubClassOf(obo:CL_4030024 obo:CL_0000066)

# Class: obo:CL_4030025 (renal cortical fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10559635") obo:IAO_0000115 obo:CL_4030025 "A fibroblast that is located in the renal cortical interstitium.")
AnnotationAssertion(terms:date obo:CL_4030025 "2022-07-05T15:50:17Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030025 "kidney cortical fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16230044") rdfs:comment obo:CL_4030025 "Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin.")
AnnotationAssertion(rdfs:label obo:CL_4030025 "renal cortical fibroblast")
EquivalentClasses(obo:CL_4030025 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005270)))

# Class: obo:CL_4030026 (BEST4+ enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0002-7431-4139>) Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:35176508") obo:IAO_0000115 obo:CL_4030026 "An enterocyte of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels.")
AnnotationAssertion(terms:date obo:CL_4030026 "2022-09-07T12:34:20Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030026 "BEST4+ enterocyte")
EquivalentClasses(obo:CL_4030026 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q8NFU0)))
SubClassOf(obo:CL_4030026 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4030027 (GABAergic amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.cell.2020.08.013") obo:IAO_0000115 obo:CL_4030027 "An amacrine cell that uses GABA as a neurotransmitter.")
AnnotationAssertion(terms:date obo:CL_4030027 "2022-10-17T12:35:11Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030027 "amacrine cell, GABAergic")
AnnotationAssertion(rdfs:label obo:CL_4030027 "GABAergic amacrine cell")
EquivalentClasses(obo:CL_4030027 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4030028 (glycinergic amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.cell.2020.08.013") obo:IAO_0000115 obo:CL_4030028 "An amacrine cell that uses glycine as a neurotransmitter.")
AnnotationAssertion(terms:date obo:CL_4030028 "2022-10-17T12:40:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030028 "amacrine cell, glycinergic")
AnnotationAssertion(rdfs:label obo:CL_4030028 "glycinergic amacrine cell")
EquivalentClasses(obo:CL_4030028 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537)))

# Class: obo:CL_4030029 (blood lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-9990-8331>) obo:IAO_0000115 obo:CL_4030029 "A lymphocyte located in blood.")
AnnotationAssertion(terms:date obo:CL_4030029 "2022-11-04T14:40:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030029 "blood lymphocyte")
EquivalentClasses(obo:CL_4030029 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000178)))

# Class: obo:CL_4030030 (peripheral blood lymphocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-9990-8331>) Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0003-2534-198X>) Annotation(oboInOwl:hasDbXref "PMID:31092833") Annotation(oboInOwl:hasDbXref "https://sciencing.com/what-peripheral-blood-4672930.html") obo:IAO_0000115 obo:CL_4030030 "A blood lymphocyte located in the flowing, circulating blood of the body.")
AnnotationAssertion(terms:date obo:CL_4030030 "2022-11-14T10:08:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030030 "peripheral blood lymphocyte")
AnnotationAssertion(rdfs:seeAlso obo:CL_4030030 "https://github.com/obophenotype/cell-ontology/pull/1725")
SubClassOf(obo:CL_4030030 obo:CL_4030029)
SubClassOf(obo:CL_4030030 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0013755))
SubClassOf(obo:CL_4030030 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0013756))

# Class: obo:CL_4030031 (interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24987007") obo:IAO_0000115 obo:CL_4030031 "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes.")
AnnotationAssertion(terms:date obo:CL_4030031 "2022-11-30T14:35:08Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4030031 "interstitial cell")
EquivalentClasses(obo:CL_4030031 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005169)))

# Class: obo:CL_4030032 (valve interstitial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-7655-4833>) Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1098/rsif.2017.0580") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1161/ATVBAHA.120.314789") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1161/JAHA.117.006339") Annotation(oboInOwl:hasDbXref "https://doi.org/10.2353/ajpath.2007.070251") obo:IAO_0000115 obo:CL_4030032 "An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.")
AnnotationAssertion(terms:date obo:CL_4030032 "2022-12-06T14:18:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "PMID:30796046") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030032 "VIC")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030032 "cardiac valve interstitial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") oboInOwl:hasExactSynonym obo:CL_4030032 "valvular interstitial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") rdfs:comment obo:CL_4030032 "Activated valve interstitial cells undergo continual turn over into deactivated fibroblasts and other cell fates (such as apoptosis).")
AnnotationAssertion(rdfs:label obo:CL_4030032 "valve interstitial cell")
EquivalentClasses(obo:CL_4030032 ObjectIntersectionOf(obo:CL_4030031 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000946)))
SubClassOf(obo:CL_4030032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))

# Class: obo:CL_4030033 (valve endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") obo:IAO_0000115 obo:CL_4030033 "An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.")
AnnotationAssertion(terms:date obo:CL_4030033 "2022-12-09T11:58:49Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "PMID:30796046") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030033 "VEC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") oboInOwl:hasExactSynonym obo:CL_4030033 "valvular endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") rdfs:comment obo:CL_4030033 "At least in some mammalian species, a valve endothelial cell expresses CD31. Valve endothelial cells can undergo an endothelial to mesenchymal transition to acquire a fibroblast or myofibroblast phenotype that leads to changes in the microenvironmental signals and facilitates tissue regeneration.")
AnnotationAssertion(rdfs:label obo:CL_4030033 "valve endothelial cell")
EquivalentClasses(obo:CL_4030033 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000946)))

# Class: obo:CL_4030034 (respiratory tract multiciliated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18757316") Annotation(oboInOwl:hasDbXref "PMID:21364219") Annotation(oboInOwl:hasDbXref "PMID:34044844") Annotation(oboInOwl:hasDbXref "PMID:37834236") obo:IAO_0000115 obo:CL_4030034 "A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis.")
AnnotationAssertion(terms:date obo:CL_4030034 "2023-01-25T11:06:01Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030034 "ciliated cell of the respiratory tract")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030034 "respiratory ciliated cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030034 "respiratory multiciliated cell")
AnnotationAssertion(rdfs:label obo:CL_4030034 "respiratory tract multiciliated cell")
EquivalentClasses(obo:CL_4030034 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))
SubClassOf(obo:CL_4030034 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4033044))

# Class: obo:CL_4030035 (dental pulp stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0002-2825-0621>) Annotation(oboInOwl:hasDbXref "DOI:10.1177/154405910208100806") obo:IAO_0000115 obo:CL_4030035 "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation.")
AnnotationAssertion(terms:date obo:CL_4030035 "2023-01-10T14:02:02Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030035 "DPSC")
AnnotationAssertion(rdfs:label obo:CL_4030035 "dental pulp stem cell")
EquivalentClasses(obo:CL_4030035 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001754)))
SubClassOf(obo:CL_4030035 obo:CL_0002148)

# Class: obo:CL_4030036 (early spermatid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/humanproteome/single+cell+type/Germ+cells#earlyspermatids") obo:IAO_0000115 obo:CL_4030036 "A spermatid in an early stage of maturation that has a round morphology and is transcriptionally active.")
AnnotationAssertion(terms:date obo:CL_4030036 "2023-02-01T13:56:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/B978-0-323-01970-5.50014-2") oboInOwl:hasExactSynonym obo:CL_4030036 "round spermatid")
AnnotationAssertion(rdfs:label obo:CL_4030036 "early spermatid")
SubClassOf(obo:CL_4030036 obo:CL_0000018)
SubClassOf(obo:CL_4030036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000079))
SubClassOf(obo:CL_4030036 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007286))

# Class: obo:CL_4030037 (late spermatid)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/humanproteome/single+cell+type/Germ+cells#latespermatids") obo:IAO_0000115 obo:CL_4030037 "A spermatid in a late stage of maturation that has an elongated morphology and is transcriptionally inert when the acrosome is fully developed.")
AnnotationAssertion(terms:date obo:CL_4030037 "2023-02-01T14:02:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/B978-0-323-01970-5.50014-2") oboInOwl:hasExactSynonym obo:CL_4030037 "elongated spermatid")
AnnotationAssertion(rdfs:label obo:CL_4030037 "late spermatid")
SubClassOf(obo:CL_4030037 obo:CL_0000018)
SubClassOf(obo:CL_4030037 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000079))
SubClassOf(obo:CL_4030037 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4030036))
SubClassOf(obo:CL_4030037 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007286))

# Class: obo:CL_4030038 (CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21281815") Annotation(oboInOwl:hasDbXref "PMID:23124355") obo:IAO_0000115 obo:CL_4030038 "A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border.")
AnnotationAssertion(terms:date obo:CL_4030038 "2023-03-07T14:17:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1002/stem.1130") oboInOwl:hasBroadSynonym obo:CL_4030038 "CD133+CD24+CD106- tubular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23124355") oboInOwl:hasBroadSynonym obo:CL_4030038 "CD24+CD133+ tubular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23124355") oboInOwl:hasBroadSynonym obo:CL_4030038 "CD24-positive tubular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23124355") rdfs:comment obo:CL_4030038 "After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration.")
AnnotationAssertion(rdfs:label obo:CL_4030038 "CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell")
SubClassOf(obo:CL_4030038 obo:CL_0002306)
SubClassOf(obo:CL_4030038 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008404))
SubClassOf(obo:CL_4030038 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001786))
SubClassOf(obo:CL_4030038 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001932))
SubClassOf(obo:CL_4030038 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000017298))

# Class: obo:CL_4030039 (von Economo neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1007/BF02970950") Annotation(oboInOwl:hasDbXref "DOI:10.1101/2022.10.12.511898") Annotation(oboInOwl:hasDbXref "PMID:32127543") obo:IAO_0000115 obo:CL_4030039 "An extratelencephalic-projecting glutamatergic cortical neuron that is morphologically-defined with a large, spindle-shaped cell body, thick bipolar dendrites with limited branching and a moderate density of spines, and often an axon initial segment that emanates from the side of the cell body. This cell type is associated with markers POU3F, BMP3 and ITGA4.")
AnnotationAssertion(terms:date obo:CL_4030039 "2023-05-25T07:29:21Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32127543") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030039 "VEN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32127543") rdfs:comment obo:CL_4030039 "In humans, a von Economo neuron is restricted to layer 5 of the anterior cingulate, frontoinsular, and medial frontopolar regions of cerebral cortex, while in some other species it is also found in the frontal and occipital poles and may not be restricted to layer 5.")
AnnotationAssertion(rdfs:label obo:CL_4030039 "von Economo neuron")
SubClassOf(obo:CL_4030039 obo:CL_4023009)
SubClassOf(obo:CL_4030039 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0070006))

# Class: obo:CL_4030040 (endometrial multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31290979") Annotation(oboInOwl:hasDbXref "PMID:37999981") Annotation(oboInOwl:hasDbXref "doi:10.1016/j.coemr.2024.100503") Annotation(oboInOwl:hasDbXref "doi:10.1038/s41591-020-1040-z") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells") obo:IAO_0000115 obo:CL_4030040 "A multi-ciliated cell of the endometrial epithelium. This cell is characterized by the presence of 9+2 motile cilia on its apical surface, which facilitates the movement of mucus across the endometrial surface.")
AnnotationAssertion(terms:date obo:CL_4030040 "2023-02-09T11:25:14Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030040 "ciliated cell of the uterus")
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030040 "uterine ciliated cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030040 "ciliated cell of the endometrium")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030040 "endometrial ciliated epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030040 "endometrium ciliated epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ttps://www.nature.com/articles/s41591-020-1040-z") rdfs:comment obo:CL_4030040 "In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted.")
AnnotationAssertion(rdfs:label obo:CL_4030040 "endometrial multiciliated epithelial cell")
EquivalentClasses(obo:CL_4030040 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004811) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0097729) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_4030041 (luminal endometrial multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41591-020-1040-z") obo:IAO_0000115 obo:CL_4030041 "A ciliated cell of the endometrial luminal epithelium. This cell is characterized by the presence of motile cilia on its apical surface.")
AnnotationAssertion(terms:date obo:CL_4030041 "2023-02-09T11:34:42Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030041 "luminal endometrial ciliated epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4030041 "luminal endometrial multiciliated epithelial cell")
SubClassOf(obo:CL_4030041 obo:CL_4030040)
SubClassOf(obo:CL_4030041 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011949))

# Class: obo:CL_4030042 (glandular endometrial multiciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41591-020-1040-z") obo:IAO_0000115 obo:CL_4030042 "A ciliated cell of the endometrial glandular epithelium. This cell is characterized by the presence of motile cilia on its apical surface.")
AnnotationAssertion(terms:date obo:CL_4030042 "2023-02-09T11:37:30Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030042 "glandular endometrial ciliated epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4030042 "glandular endometrial multiciliated epithelial cell")
SubClassOf(obo:CL_4030042 obo:CL_4030040)
SubClassOf(obo:CL_4030042 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012276))

# Class: obo:CL_4030043 (matrix D1 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030043 "A DRD1-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum.")
AnnotationAssertion(terms:date obo:CL_4030043 "2023-06-02T14:05:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030043 "D1-matrix")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030043 "D1M")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030043 "matrix D1-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030043 "In Rhesus macaques, both matrix D1 and D2 medium spiny neuron cell types have been noted to have enriched gene expression of the following: EPHA4, GDA, STXBP6, and SEMA3E. Broadly understood, matrix MSNs receive neocortical inputs from the associative and sensorimotor cortex and give rise to the direct and indirect pathways.")
AnnotationAssertion(rdfs:label obo:CL_4030043 "matrix D1 medium spiny neuron")
SubClassOf(obo:CL_4030043 obo:CL_4023026)
SubClassOf(obo:CL_4030043 ObjectSomeValuesFrom(obo:RO_0002100 ObjectIntersectionOf(obo:UBERON_0027368 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005382))))

# Class: obo:CL_4030047 (matrix D2 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030047 "A DRD2-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum.")
AnnotationAssertion(terms:date obo:CL_4030047 "2023-06-02T14:40:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030047 "D2-matrix")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030047 "D2M")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030047 "matrix D2-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030047 "In Rhesus macaques, both matrix D1 and D2 medium spiny neuron cell types have been noted to have enriched gene expression of the following: EPHA4, GDA, STXBP6, and SEMA3E. Broadly understood, matrix MSNs receive neocortical inputs from the associative and sensorimotor cortex and give rise to the direct and indirect pathways.")
AnnotationAssertion(rdfs:label obo:CL_4030047 "matrix D2 medium spiny neuron")
SubClassOf(obo:CL_4030047 obo:CL_4023029)
SubClassOf(obo:CL_4030047 ObjectSomeValuesFrom(obo:RO_0002100 ObjectIntersectionOf(obo:UBERON_0027368 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005382))))

# Class: obo:CL_4030048 (striosomal D1 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030048 "A DRD1-expressing medium spiny neuron that is part of a striosome of dorsal striatum.")
AnnotationAssertion(terms:date obo:CL_4030048 "2023-06-02T14:50:43Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") oboInOwl:hasExactSynonym obo:CL_4030048 "striosome D1 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030048 "D1-striosome")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030048 "D1S")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030048 "striosome D1-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030048 "In Rhesus macaques, both striosomal D1 and D2 medium spiny neuron (MSN) cell types have been noted to have enriched gene expression of the following: KCNT1, KHDRBS3, FAM163A, BACH2, and KCNIP1. Striosomal MSN activations have been noted to influence cognitive and emotional decision making and value-based learning. In contrast to matrix MSNs, striosomal MSNs receive input from limbic territories, including the anterior cingulate cortex, orbitofrontal cortex, and anterior insular cortex, and project directly to midbrain dopamine neurons.")
AnnotationAssertion(rdfs:label obo:CL_4030048 "striosomal D1 medium spiny neuron")
SubClassOf(obo:CL_4030048 obo:CL_4023026)
SubClassOf(obo:CL_4030048 ObjectSomeValuesFrom(obo:RO_0002100 ObjectIntersectionOf(obo:UBERON_0027371 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005382))))

# Class: obo:CL_4030049 (striosomal D2 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030049 "A DRD2-expressing medium spiny neuron that is part of a striosome of dorsal striatum.")
AnnotationAssertion(terms:date obo:CL_4030049 "2023-06-02T15:03:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") oboInOwl:hasExactSynonym obo:CL_4030049 "striosome D2 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030049 "D2-striosome")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030049 "D2S")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030049 "striosome D2-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030049 "In Rhesus macaques, both striosomal D1 and D2 medium spiny neuron (MSN) cell types have been noted to have enriched gene expression of the following: KCNT1, KHDRBS3, FAM163A, BACH2, and KCNIP1. Striosomal MSN activations have been noted to influence cognitive and emotional decision making and value-based learning. In contrast to matrix MSNs, striosomal MSNs receive input from limbic territories, including the anterior cingulate cortex, orbitofrontal cortex, and anterior insular cortex, and project directly to midbrain dopamine neurons.")
AnnotationAssertion(rdfs:label obo:CL_4030049 "striosomal D2 medium spiny neuron")
SubClassOf(obo:CL_4030049 obo:CL_4023029)
SubClassOf(obo:CL_4030049 ObjectSomeValuesFrom(obo:RO_0002100 ObjectIntersectionOf(obo:UBERON_0027371 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005382))))

# Class: obo:CL_4030050 (D1/D2-hybrid medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030050 "A medium spiny neuron that expresses both DRD1 and DRD2 and is part of an extra-striosomal part of dorsal striatum.")
AnnotationAssertion(terms:date obo:CL_4030050 "2023-06-02T15:19:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030050 "D1/2")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030050 "D1/D2 hybrid")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030050 "D1/D2-hybrid MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030050 "hybrid D1/2 cell type")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030050 "It has been noted in non-human primate species that the D1/D2-hybrid medium spiny neuron (D1/2) cell type shows the same amount of DRD1 expression as nearby D1 medium spiny neurons but far less DRD2 expression compared to nearby D2 medium spiny neurons. In Rhesus macaques, RXFP1 has been noted as a highly specific marker gene for the D1/2 cell type. The D1/2 cell type has also been described as having characteristics similar to a novel medium spiny neuron described in rodents (D1H or eccentric spiny projection neuron). Although an extrastriosomal cell type, the D1/2 cell type had been noted to express many of the genes associated with striosome, suggesting a possible homology to ‘‘exo-patch’’ cells.")
AnnotationAssertion(rdfs:label obo:CL_4030050 "D1/D2-hybrid medium spiny neuron")
SubClassOf(obo:CL_4030050 obo:CL_1001474)
SubClassOf(obo:CL_4030050 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005382))
SubClassOf(obo:CL_4030050 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001175))
SubClassOf(obo:CL_4030050 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001177))

# Class: obo:CL_4030051 (nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030051 "A DRD1-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle.")
AnnotationAssertion(terms:date obo:CL_4030051 "2023-06-14T13:03:50Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") oboInOwl:hasExactSynonym obo:CL_4030051 "NAc shell and OT D1 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030051 "D1Sh")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030051 "NAc shell and OT D1-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030051 "In Rhesus macaques, both nucleus accumbens shell and olfactory tubercle D1 and D2 medium spiny neuron cell types have been noted to have enriched gene expression of the following: GREB1L, ARHGAP6, and GRIA4.")
AnnotationAssertion(rdfs:label obo:CL_4030051 "nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron")
SubClassOf(obo:CL_4030051 obo:CL_1001474)
SubClassOf(obo:CL_4030051 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005403))
SubClassOf(obo:CL_4030051 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001175))

# Class: obo:CL_4030052 (nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030052 "A DRD2-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle.")
AnnotationAssertion(terms:date obo:CL_4030052 "2023-06-14T13:27:51Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") oboInOwl:hasExactSynonym obo:CL_4030052 "NAc shell and OT D2 medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030052 "D2Sh")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030052 "NAc shell and OT D2-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030052 "nucleus accumbens shell and olfactory tubercle D2-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030052 "In Rhesus macaques, both nucleus accumbens shell and olfactory tubercle D1 and D2 medium spiny neuron cell types have been noted to have enriched gene expression of the following: GREB1L, ARHGAP6, and GRIA4.")
AnnotationAssertion(rdfs:label obo:CL_4030052 "nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron")
SubClassOf(obo:CL_4030052 obo:CL_1001474)
SubClassOf(obo:CL_4030052 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005403))
SubClassOf(obo:CL_4030052 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001177))

# Class: obo:CL_4030053 (Islands of Calleja granule cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34795450") Annotation(oboInOwl:hasDbXref "PMID:37898623") Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") obo:IAO_0000115 obo:CL_4030053 "A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors.")
AnnotationAssertion(terms:contributor obo:CL_4030053 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4030053 "2023-06-14T13:37:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030053 "D1-ICj")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cub.2021.10.015") rdfs:comment obo:CL_4030053 "In Rhesus macaques, the Island of Calleja granule cell type has been noted to have enriched gene expression of CPNE4.")
AnnotationAssertion(rdfs:label obo:CL_4030053 "Islands of Calleja granule cell")
SubClassOf(obo:CL_4030053 obo:CL_0000120)
SubClassOf(obo:CL_4030053 obo:CL_0000617)
SubClassOf(obo:CL_4030053 ObjectSomeValuesFrom(obo:RO_0002100 ObjectIntersectionOf(obo:UBERON_0001881 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005403))))
SubClassOf(obo:CL_4030053 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001175))

# Class: obo:CL_4030054 (D1-NUDAP medium spiny neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030054 "STRv D1 NUDAP MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") obo:IAO_0000115 obo:CL_4030054 "A DRD1-expressing medium spiny neuron that is part of dense, RXFP1-positive cell islands throughout the nucleus accumbens, putamen, and near the adjacent septal nuclei.")
AnnotationAssertion(terms:date obo:CL_4030054 "2023-06-14T14:46:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") oboInOwl:hasExactSynonym obo:CL_4030054 "RXFP1-positive interface island D1-medium spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030054 "D1-NUDAP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") rdfs:comment obo:CL_4030054 "Regarding the abbreviation D1-NUDAP, NUDAP stands for \"neurochemically unique domains in the accumbens and putamen\". In Rhesus macaques, the RXFP1-positive interface island D1-medium spiny neuron (D1-NUDAP) has been noted to have upregulation of OPRM1 compared to DRD1-expressing medium spiny neurons located outside of the D1-exclusive island and in Islands of Calleja. Kappa-opioid receptor gene (OPRK1) has been noted to be absent from D1-NUDAP cells. Many striosome-specific markers have been noted to be upregulated in D1-NUDAP cells, including KCNIP1, KCNT1, KHDRBS3, and BACH2. PDYN, an acknowledged D1-striosome marker gene, has also been noted to be expressed in D1-NUDAPs. D1-NUDAPs also express some genes found to be selectively expressed in the matrix, including STXBP6, GDA, and SEMA3E. Gene enrichment analysis has revealed that D1-NUDAP neurons express genes that have been implicated in drug addiction and many other functions.")
AnnotationAssertion(rdfs:label obo:CL_4030054 "D1-NUDAP medium spiny neuron")
SubClassOf(obo:CL_4030054 obo:CL_1001474)
SubClassOf(obo:CL_4030054 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005403))
SubClassOf(obo:CL_4030054 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001175))
SubClassOf(obo:CL_4030054 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001666))

# Class: obo:CL_4030055 (intermediate cell of urothelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") obo:IAO_0000115 obo:CL_4030055 "A urothelial cell that is part of the regenerative layer(s) of cells directly superficial to basal cells in urothelium. The layer of intermediate cells in the urothelium ranges from one to several layers thick depending on the species with intermediate cells attached to adjacent cell layers and one another via desmosomes.")
AnnotationAssertion(terms:contributor obo:CL_4030055 "https://orcid.org/0000-0003-3065-9183")
AnnotationAssertion(terms:date obo:CL_4030055 "2023-06-16T07:53:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4030055 "FMA:84155")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-14366-4_8") oboInOwl:hasExactSynonym obo:CL_4030055 "urothelial intermediate cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") rdfs:comment obo:CL_4030055 "It has been noted in at least some mammalian species that the urothelial intermediate cell type is similar to basal cells by expressing CK17 and (unlike umbrella cells) p63 but is positive for uroplakins (UPK) and negative for CK5. Urothelial intermediate cells have also been noted to be larger in diameter than urothelial basal cells.")
AnnotationAssertion(rdfs:label obo:CL_4030055 "intermediate cell of urothelium")
SubClassOf(obo:CL_4030055 obo:CL_0000731)

# Class: obo:CL_4030056 (umbrella cell of urothelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") obo:IAO_0000115 obo:CL_4030056 "A urothelial cell that is terminally differentiated and part of the urothelial apical surface that forms the high-resistance barrier of urothelium. Umbrella cells have been described as the largest of urothelial cell types, highly polarized, and, in some species, multinucleated. In the relaxed state, these cells form a dome-shaped structure at the apical pole and can also cover multiple underlying intermediate cells, leading to the name umbrella cells. In contrast, these cells flatten when the bladder is filled.")
AnnotationAssertion(terms:contributor obo:CL_4030056 "https://orcid.org/0000-0003-3065-9183")
AnnotationAssertion(terms:date obo:CL_4030056 "2023-06-16T07:59:43Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4030056 "FMA:84149")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") oboInOwl:hasExactSynonym obo:CL_4030056 "facet cell of urothelium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") oboInOwl:hasExactSynonym obo:CL_4030056 "superficial cell of urothelium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41385-022-00565-0") rdfs:comment obo:CL_4030056 "Umbrella cells are attached to sub-superficial cell layers via desmosomes, while tight junctions localized between superficial cells aid in forming a high-resistance barrier function. Another distinguishing feature of an umbrella cell type is the presence of subapical discoidal/fusiform-shaped vesicles contributing to the plasticity in urothelial cell surface area through a regulated process of endocytosis/exocytosis. It has been noted in at least some mammalian species that the urothelial umbrella cell type expresses UPK1A, UPK1B, UPK2 and UPK3A. Unlike intermediate and basal cells of the urothelium, CK17 is reported to be completely absent and p63 not expressed in umbrella cells.")
AnnotationAssertion(rdfs:label obo:CL_4030056 "umbrella cell of urothelium")
SubClassOf(obo:CL_4030056 obo:CL_0000731)

# Class: obo:CL_4030057 (eccentric medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cell.2018.07.028") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.10.12.511898") obo:IAO_0000115 obo:CL_4030057 "A medium spiny neuron that exhibits transcriptional divergence from direct and indirect spiny projection neurons, for example, enrichment in Casz1, Otof, Cacng5 and Pcdh8 noted in mice. Whilst in general medium spiny neurons have been found to be differentially distributed across the basal ganglia, the eccentric medium spiny neuron cell type has been found to be more evenly distributed throughout cerebral nuclei.")
AnnotationAssertion(terms:date obo:CL_4030057 "2023-06-23T14:59:36Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cell.2018.07.028") oboInOwl:hasExactSynonym obo:CL_4030057 "eccentric spiny projection neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cell.2018.07.028") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030057 "eSPN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.10.12.511898") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030057 "eccentric MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cell.2018.07.028") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030057 "eccentric SPN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.cell.2018.07.028") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.10.12.511898") rdfs:comment obo:CL_4030057 "The term “eccentric” is used in the name eccentric medium spiny neuron (MSN) due to the exhibited transcriptional divergence from canonical spiny projection neurons. It has been noted in at least one study that an eccentric MSN differs in expression from direct and indirect MSNs by 110 genes (more than the 68 that distinguished direct and indirect spiny projection neurons from each other) and expresses many genes that have little expression in the rest of the striatum. It also has been noted in at least one human study that most eccentric MSNs expressed only DRD1, but many in the basal ganglia co-expressed DRD1 and DRD2, suggesting regional specialization of a more broadly distributed cell type.")
AnnotationAssertion(rdfs:label obo:CL_4030057 "eccentric medium spiny neuron")
SubClassOf(obo:CL_4030057 obo:CL_1001474)

# Class: obo:CL_4030058 (TCR-positive macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0001-9990-8331>) Annotation(oboInOwl:hasDbXref "PMID:26074923") obo:IAO_0000115 obo:CL_4030058 "A macrophage that expresses the T cell receptor complex at the cell surface.")
AnnotationAssertion(terms:contributor obo:CL_4030058 <https://orcid.org/0000-0003-3308-6245>)
AnnotationAssertion(terms:date obo:CL_4030058 "2023-09-26T12:27:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26074923") oboInOwl:hasExactSynonym obo:CL_4030058 "T cell receptor positive macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26074923") oboInOwl:hasExactSynonym obo:CL_4030058 "TCR+ macrophage")
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:37500727") oboInOwl:hasRelatedSynonym obo:CL_4030058 "TCR.macs")
AnnotationAssertion(rdfs:label obo:CL_4030058 "TCR-positive macrophage")
EquivalentClasses(obo:CL_4030058 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042101)))

# Class: obo:CL_4030059 (L2/3 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030059 "L2/3 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25622573") Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4030059 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential.")
AnnotationAssertion(terms:contributor obo:CL_4030059 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030059 "2023-10-10T14:10:21Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4030059 "ILX:0770156")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030059 "L2/3 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") rdfs:comment obo:CL_4030059 "Hystorically, the L2/3 intratelencephalic projectic glutametergic neuron was known to have its soma in cortical layer 2/3. MERFISH data showed that this intratelencephalic-projecting glutametergic neuron can have its soma in layer 2/3, 4B, 4C. The position of the soma in layer 4b and 4C is less frequent for this neuronal type in comparison to cortical layer 2/3.")
AnnotationAssertion(rdfs:label obo:CL_4030059 "L2/3 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030059 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440000)))

# Class: obo:CL_4030060 (L2 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030060 "L2 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") obo:IAO_0000115 obo:CL_4030060 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2.")
AnnotationAssertion(terms:contributor obo:CL_4030060 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030060 "2023-10-10T14:10:36Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030060 "L2 IT")
AnnotationAssertion(rdfs:label obo:CL_4030060 "L2 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030060 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005391)))

# Class: obo:CL_4030061 (L3 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030061 "L3 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") obo:IAO_0000115 obo:CL_4030061 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3.")
AnnotationAssertion(terms:contributor obo:CL_4030061 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030061 "2023-10-10T14:10:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030061 "L3 IT")
AnnotationAssertion(rdfs:label obo:CL_4030061 "L3 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030061 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005392)))

# Class: obo:CL_4030062 (L4/5 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030062 "L4/5 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") obo:IAO_0000115 obo:CL_4030062 "An intratelencephalic-projecting glutamatergic with a soma located in cortical layer 4/5.")
AnnotationAssertion(terms:contributor obo:CL_4030062 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030062 "2023-10-10T14:11:04Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030062 "L4/5 IT")
AnnotationAssertion(rdfs:label obo:CL_4030062 "L4/5 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030062 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440001)))

# Class: obo:CL_4030063 (L4 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030063 "L4 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4030063 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B.")
AnnotationAssertion(terms:contributor obo:CL_4030063 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030063 "2023-10-10T14:11:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030063 "L4 IT")
AnnotationAssertion(rdfs:comment obo:CL_4030063 "Historically, the L4 intratelencephalic projectic glutametergic neuron was known to have its soma in cortical layer 4. MERFISH data showed that this intratelencephalic-projecting glutametergic neuron can also have its soma in layer 3.")
AnnotationAssertion(rdfs:label obo:CL_4030063 "L4 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030063 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005393)))

# Class: obo:CL_4030064 (L5 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030064 "L5 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37609206") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4030064 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5.")
AnnotationAssertion(terms:contributor obo:CL_4030064 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030064 "2023-10-10T14:11:59Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4030064 "ILX:0770157")
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:37292694") oboInOwl:hasRelatedSynonym obo:CL_4030064 "L5 IT")
AnnotationAssertion(rdfs:label obo:CL_4030064 "L5 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030064 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005394)))

# Class: obo:CL_4030065 (L6 intratelencephalic projecting glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030065 "L6 IT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37609206") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4030065 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted.")
AnnotationAssertion(terms:contributor obo:CL_4030065 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030065 "2023-10-10T14:12:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4030065 "ILX:0770158")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030065 "L6 IT")
AnnotationAssertion(rdfs:label obo:CL_4030065 "L6 intratelencephalic projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030065 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005395)))

# Class: obo:CL_4030066 (ureteric bud cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17133361") Annotation(oboInOwl:hasDbXref "PMID:24183650") Annotation(oboInOwl:hasDbXref "PMID:9374839") obo:IAO_0000115 obo:CL_4030066 "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion.")
AnnotationAssertion(terms:contributor obo:CL_4030066 "https://orcid.org/0000-0002-1425-877X")
AnnotationAssertion(terms:date obo:CL_4030066 "2023-10-13T11:22:42Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24183650") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030066 "UB cell")
AnnotationAssertion(rdfs:label obo:CL_4030066 "ureteric bud cell")
EquivalentClasses(obo:CL_4030066 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000084)))
SubClassOf(Annotation(oboInOwl:hasDbXref "PMID:9374839") obo:CL_4030066 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_2001013))

# Class: obo:CL_4030067 (L5/6 near-projecting glutamatergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") obo:IAO_0000115 obo:CL_4030067 "A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6.")
AnnotationAssertion(terms:contributor obo:CL_4030067 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030067 "2023-11-17T11:35:06Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030067 "L5/6 NP")
AnnotationAssertion(rdfs:label obo:CL_4030067 "L5/6 near-projecting glutamatergic neuron")
EquivalentClasses(obo:CL_4030067 ObjectIntersectionOf(obo:CL_4023012 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8440002)))

# Class: obo:CL_4030068 (L6 intratelencephalic projecting Car3 glutamatergic neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4030068 "L6 IT Car3")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "doi:10.1007/s00424-024-02923-2") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.30.518285") obo:IAO_0000115 obo:CL_4030068 "A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6.")
AnnotationAssertion(terms:contributor obo:CL_4030068 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:date obo:CL_4030068 "2023-11-23T09:16:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.06.515349") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030068 "L6 IT Car3 glutamatergic neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.06.515349") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030068 "L6 IT Car3")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030068 "L6 IT Car3 neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.30.518285") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030068 "L6-IT-Car3")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4030068 "L6-IT-Car3 cell")
AnnotationAssertion(rdfs:label obo:CL_4030068 "L6 intratelencephalic projecting Car3 glutamatergic neuron")
EquivalentClasses(obo:CL_4030068 ObjectIntersectionOf(obo:CL_4023040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005395) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000004919)))

# Class: obo:CL_4032000 (club-like cell of the urethral epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30566875") Annotation(oboInOwl:hasDbXref "PMID:32497356") obo:IAO_0000115 obo:CL_4032000 "An epithelial cell of the urethra that has an expression profile similar to lung club cells. Club-like cells of the urethra epithelium are similar to lung club cells in their expression of SCGB1A1 and in their enrichment of immunomodulatory programs.")
AnnotationAssertion(obo:IAO_0000116 obo:CL_4032000 "The term \"club-like\" is used to disambiguate from club cells which CL defines as a type of bronchial epithelial cell. This seems to reflect common usage of club cell when used without location (club cell seems to mean bronchial club cell, unless it is proceded or preceded by something that says it is not bronchial). In the literature, the name \"club-like\" isn't used.")
AnnotationAssertion(terms:contributor obo:CL_4032000 <http://orcid.org/0000-0001-6757-4744>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4032000 "club cell of the urethra epithelium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-7258-9596") oboInOwl:hasExactSynonym obo:CL_4032000 "club-like cell of the prostatic urethra epithelium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30566875") oboInOwl:hasExactSynonym obo:CL_4032000 "prostate club cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30566875") rdfs:comment obo:CL_4032000 "Club cells typically refer to bronchiolar exocrine cells found in the lungs. This cell type is given the name club cell due to their similarity to club cells in the lungs.")
AnnotationAssertion(rdfs:label obo:CL_4032000 "club-like cell of the urethral epithelium")
SubClassOf(obo:CL_4032000 obo:CL_1000296)
SubClassOf(obo:CL_4032000 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000014505))

# Class: obo:CL_4032001 (reelin GABAergic cortical interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23803971") obo:IAO_0000115 obo:CL_4032001 "A GABAergic interneuron located in the cerebral cortex that expresses reelin (rln).")
AnnotationAssertion(terms:contributor obo:CL_4032001 <http://orcid.org/0000-0001-6757-4744>)
AnnotationAssertion(terms:contributor obo:CL_4032001 "http://orcid.org/0000-0001-5501-853X")
AnnotationAssertion(terms:contributor obo:CL_4032001 "http://orcid.org/0000-0001-7476-6306")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29904965") oboInOwl:hasExactSynonym obo:CL_4032001 "rln GABAergic cortical interneuron")
AnnotationAssertion(rdfs:label obo:CL_4032001 "reelin GABAergic cortical interneuron")
EquivalentClasses(obo:CL_4032001 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013879)))

# Class: obo:CL_4033000 (endothelial cell of venule of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28217126") obo:IAO_0000115 obo:CL_4033000 "A(n) endothelial cell that is part of a(n) venule of lymph node.")
AnnotationAssertion(terms:contributor obo:CL_4033000 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033000 "endothelial cell of venule of lymph node")
EquivalentClasses(obo:CL_4033000 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410041)))

# Class: obo:CL_4033001 (endothelial cell of arteriole of lymph node)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28217126") obo:IAO_0000115 obo:CL_4033001 "A(n) endothelial cell that is part of a(n) arteriole of lymph node.")
AnnotationAssertion(terms:contributor obo:CL_4033001 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033001 "endothelial cell of arteriole of lymph node")
EquivalentClasses(obo:CL_4033001 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410042)))

# Class: obo:CL_4033002 (neuroendocrine cell of epithelium of crypt of Lieberkuhn)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31390635") obo:IAO_0000115 obo:CL_4033002 "A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn.")
AnnotationAssertion(terms:contributor obo:CL_4033002 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033002 "neuroendocrine cell of epithelium of crypt of Lieberkuhn")
EquivalentClasses(obo:CL_4033002 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011184)))

# Class: obo:CL_4033003 (myoepithelial cell of bronchus submucosal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19996346") Annotation(oboInOwl:hasDbXref "PMID:5487122") obo:IAO_0000115 obo:CL_4033003 "A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland.")
AnnotationAssertion(terms:contributor obo:CL_4033003 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033003 "myoepithelial cell of bronchus submucosal gland")
EquivalentClasses(obo:CL_4033003 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410043)))

# Class: obo:CL_4033004 (smooth muscle cell of taenia coli)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10715339") Annotation(oboInOwl:hasDbXref "PMID:22320805") obo:IAO_0000115 obo:CL_4033004 "A(n) smooth muscle cell that is part of a(n) taenia coli.")
AnnotationAssertion(terms:contributor obo:CL_4033004 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033004 "smooth muscle cell of taenia coli")
EquivalentClasses(obo:CL_4033004 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012419)))
SubClassOf(obo:CL_4033004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_4033005 (serous secreting cell of bronchus submucosal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5487122") Annotation(oboInOwl:hasDbXref "PMID:9651178") obo:IAO_0000115 obo:CL_4033005 "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland.")
AnnotationAssertion(terms:contributor obo:CL_4033005 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033005 "serous secreting cell of bronchus submucosal gland")
EquivalentClasses(obo:CL_4033005 ObjectIntersectionOf(obo:CL_0000313 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410043)))

# Class: obo:CL_4033006 (endothelial cell of efferent lymphatic vessel)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32094869") obo:IAO_0000115 obo:CL_4033006 "A(n) endothelial cell that is part of a(n) efferent lymphatic vessel.")
AnnotationAssertion(terms:contributor obo:CL_4033006 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033006 "endothelial cell of efferent lymphatic vessel")
EquivalentClasses(obo:CL_4033006 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010397)))

# Class: obo:CL_4033007 (brush cell of epithelium of lobar bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15817800") obo:IAO_0000115 obo:CL_4033007 "A(n) brush cell that is part of a(n) epithelium of lobar bronchus.")
AnnotationAssertion(terms:contributor obo:CL_4033007 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033007 "brush cell of epithelium of lobar bronchus")
EquivalentClasses(obo:CL_4033007 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002339)))

# Class: obo:CL_4033008 (vein endothelial cell of respiratory system)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34030460") obo:IAO_0000115 obo:CL_4033008 "A(n) vein endothelial cell that is part of a(n) respiratory system.")
AnnotationAssertion(terms:contributor obo:CL_4033008 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033008 "vein endothelial cell of respiratory system")
EquivalentClasses(obo:CL_4033008 ObjectIntersectionOf(obo:CL_0002543 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001004)))

# Class: obo:CL_4033009 (goblet cell of epithelium of lobar bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18757316") obo:IAO_0000115 obo:CL_4033009 "A(n) goblet cell that is part of a(n) epithelium of lobar bronchus.")
AnnotationAssertion(terms:contributor obo:CL_4033009 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033009 "goblet cell of epithelium of lobar bronchus")
EquivalentClasses(obo:CL_4033009 ObjectIntersectionOf(obo:CL_0000160 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002339)))

# Class: obo:CL_4033010 (neuroendocrine cell of epithelium of lobar bronchus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26711336") Annotation(oboInOwl:hasDbXref "PMID:33355253") obo:IAO_0000115 obo:CL_4033010 "A(n) neuroendocrine cell that is part of a(n) epithelium of lobar bronchus.")
AnnotationAssertion(terms:contributor obo:CL_4033010 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033010 "neuroendocrine cell of epithelium of lobar bronchus")
EquivalentClasses(obo:CL_4033010 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002339)))

# Class: obo:CL_4033011 (smooth muscle cell of large intestine smooth muscle circular layer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24997029") obo:IAO_0000115 obo:CL_4033011 "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer.")
AnnotationAssertion(terms:contributor obo:CL_4033011 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033011 "smooth muscle cell of large intestine smooth muscle circular layer")
EquivalentClasses(obo:CL_4033011 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012398)))
SubClassOf(obo:CL_4033011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_4033012 (smooth muscle cell of large intestine smooth muscle longitudinal layer)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24997029") obo:IAO_0000115 obo:CL_4033012 "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer.")
AnnotationAssertion(terms:contributor obo:CL_4033012 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(rdfs:label obo:CL_4033012 "smooth muscle cell of large intestine smooth muscle longitudinal layer")
EquivalentClasses(obo:CL_4033012 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012399)))
SubClassOf(obo:CL_4033012 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))

# Class: obo:CL_4033013 (suprabasal keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22375063") Annotation(oboInOwl:hasDbXref "PMID:35883599") Annotation(oboInOwl:hasDbXref "PMID:9520465") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/humanproteome/single+cell+type/squamous+epithelial+cells#suprabasalkeratinocytes") obo:IAO_0000115 obo:CL_4033013 "A keratinocyte that resides in the epidermal suprabasal layer and expresses differentiation markers, including keratin 1 and keratin 10, in both humans and mice. In human interfollicular epidermis, this cell retains proliferative capacity and possesses retrodifferentiation potential, acquiring basal-like properties during wound healing or basement membrane contact.")
AnnotationAssertion(terms:contributor obo:CL_4033013 <http://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4033013 "2023-02-02T11:17:04Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033013 "suprabasal keratinocyte")
EquivalentClasses(obo:CL_4033013 ObjectIntersectionOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010402)))
SubClassOf(obo:CL_4033013 obo:CL_7770004)

# Class: obo:CL_4033014 (peg cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2210508") Annotation(oboInOwl:hasDbXref "PMID:22911892") Annotation(oboInOwl:hasDbXref "PMID:30023181") obo:IAO_0000115 obo:CL_4033014 "A small, narrow, peg-shaped epithelial cell with little cytoplasm that is part of oviduct epithelium. This cell is rarer than the ciliated and secretory epithelial cells of the fallopian tube epithelium and is often found intercalated between them. Peg cells are generally distributed basally along the epithelium and have been found in high concentrations at the fimbriated, distal end of the fallopian tube in humans. It may have a regenerative/stem-cell function. In humans, markers include EPCAM, CD44, and ITGA6.")
AnnotationAssertion(terms:contributor obo:CL_4033014 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033014 "2023-02-02T15:07:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22911892") oboInOwl:hasExactSynonym obo:CL_4033014 "FTE stem-like cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22911892") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4033014 "FTESC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22911892") oboInOwl:hasExactSynonym obo:CL_4033014 "fallopian tube epithelial stem-like cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22911892") oboInOwl:hasExactSynonym obo:CL_4033014 "intercalary cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22911892") rdfs:comment obo:CL_4033014 "In vitro evidence supports a stem-cell/regenerative function for these cells")
AnnotationAssertion(rdfs:label obo:CL_4033014 "peg cell")
SubClassOf(obo:CL_4033014 obo:CL_4052019)
SubClassOf(obo:CL_4033014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004804))

# Class: obo:CL_4033015 (retinal astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25236977") Annotation(oboInOwl:hasDbXref "PMID:33796062") obo:IAO_0000115 obo:CL_4033015 "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons.")
AnnotationAssertion(terms:contributor obo:CL_4033015 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033015 "2023-03-02T14:38:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33796062") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4033015 "retinal astroglia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32555229") Annotation(oboInOwl:hasDbXref "PMID:33796062") rdfs:comment obo:CL_4033015 "In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive.")
AnnotationAssertion(rdfs:label obo:CL_4033015 "retinal astrocyte")
EquivalentClasses(obo:CL_4033015 ObjectIntersectionOf(obo:CL_0000127 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000966)))

# Class: obo:CL_4033016 (secondary crest myofibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31331942") Annotation(oboInOwl:hasDbXref "PMID:33624948") obo:IAO_0000115 obo:CL_4033016 "A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood.")
AnnotationAssertion(terms:contributor obo:CL_4033016 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033016 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033016 "2023-03-16T09:17:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31331942") oboInOwl:hasExactSynonym obo:CL_4033016 "secondary-crest myofibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33624948") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033016 "SCMF")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25448080") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4033016 "SCMFs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31331942") oboInOwl:hasRelatedSynonym obo:CL_4033016 "alveolar myofibroblast")
AnnotationAssertion(rdfs:label obo:CL_4033016 "secondary crest myofibroblast")
SubClassOf(obo:CL_4033016 obo:CL_0000186)
SubClassOf(obo:CL_4033016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000114))
SubClassOf(obo:CL_4033016 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0048286))

# Class: obo:CL_4033017 (bronchiolar smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:9781260462982") Annotation(oboInOwl:hasDbXref "PMID:15347627") obo:IAO_0000115 obo:CL_4033017 "A smooth muscle cell that is part of a bronchiole.")
AnnotationAssertion(terms:contributor obo:CL_4033017 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033017 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033017 "2023-03-16T09:38:17Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033017 "bronchiolar smooth muscle cell")
EquivalentClasses(obo:CL_4033017 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002186)))
SubClassOf(obo:CL_4033017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004515))

# Class: obo:CL_4033018 (lung megakaryocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33351116") obo:IAO_0000115 obo:CL_4033018 "A megakaryocyte that is resident in the lung connective tissue.")
AnnotationAssertion(terms:contributor obo:CL_4033018 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033018 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033018 "2023-03-16T11:31:23Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36524131") oboInOwl:hasExactSynonym obo:CL_4033018 "lung resident megakaryocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36524131") oboInOwl:hasExactSynonym obo:CL_4033018 "lung-resident megakaryocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36524131") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033018 "MKL")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33351116") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4033018 "lung MKs")
AnnotationAssertion(rdfs:label obo:CL_4033018 "lung megakaryocyte")
EquivalentClasses(obo:CL_4033018 ObjectIntersectionOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000114)))
SubClassOf(obo:CL_4033018 obo:CL_0000556)

# Class: obo:CL_4033019 (ON-blue cone bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033019 "An ON bipolar cell type with dendrites selectively contacting S-cones.")
AnnotationAssertion(terms:contributor obo:CL_4033019 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033019 "2023-04-04T09:48:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033019 "BB cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") rdfs:comment obo:CL_4033019 "The axons of a blue cone bipolar cell terminate close to the ganglion cell layer, where they transfer the S-cone ON signal to small bistratified ganglion cells. Other targets of a blue cone bipolar cell include amacrine cells and possibly large bistratified ganglion cells.")
AnnotationAssertion(rdfs:label obo:CL_4033019 "ON-blue cone bipolar cell")
SubClassOf(obo:CL_4033019 obo:CL_0000749)

# Class: obo:CL_4033020 (mucus secreting cell of trachea gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18931053") Annotation(oboInOwl:hasDbXref "PMID:29656943") obo:IAO_0000115 obo:CL_4033020 "A mucus secreting cell that is part of a submucosal gland of the trachea.")
AnnotationAssertion(terms:contributor obo:CL_4033020 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033020 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033020 "2023-03-16T13:03:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18931053") oboInOwl:hasExactSynonym obo:CL_4033020 "tracheal submucosal gland mucous cell")
AnnotationAssertion(rdfs:label obo:CL_4033020 "mucus secreting cell of trachea gland")
EquivalentClasses(obo:CL_4033020 ObjectIntersectionOf(obo:CL_0000319 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005203)))

# Class: obo:CL_4033021 (myoepithelial cell of trachea gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29656943") obo:IAO_0000115 obo:CL_4033021 "A myoepithelial cell that is part of a submucosal gland of the trachea.")
AnnotationAssertion(terms:contributor obo:CL_4033021 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033021 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033021 "2023-03-16T13:36:43Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033021 "myoepithelial cell of trachea gland")
EquivalentClasses(obo:CL_4033021 ObjectIntersectionOf(obo:CL_0000185 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005203)))

# Class: obo:CL_4033022 (mucus secreting cell of bronchus submucosal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19965983") obo:IAO_0000115 obo:CL_4033022 "A mucus secreting cell of a submucosal gland of the bronchus.")
AnnotationAssertion(terms:contributor obo:CL_4033022 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033022 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033022 "2023-03-16T15:12:52Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5487122") oboInOwl:hasExactSynonym obo:CL_4033022 "bronchial gland mucous cell")
AnnotationAssertion(rdfs:label obo:CL_4033022 "mucus secreting cell of bronchus submucosal gland")
EquivalentClasses(obo:CL_4033022 ObjectIntersectionOf(obo:CL_0000319 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410043)))

# Class: obo:CL_4033023 (airway submucosal gland collecting duct epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25648514") Annotation(oboInOwl:hasDbXref "PMID:29656943") obo:IAO_0000115 obo:CL_4033023 "An epithelial cell that is part of a collecting duct of an airway submucosal gland.")
AnnotationAssertion(terms:contributor obo:CL_4033023 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033023 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033023 "2023-03-16T15:20:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033023 "airway submucosal gland collecting duct epithelial cell")
SubClassOf(obo:CL_4033023 obo:CL_0000066)
SubClassOf(obo:CL_4033023 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410077))

# Class: obo:CL_4033024 (airway submucosal gland duct basal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29656943") Annotation(oboInOwl:hasDbXref "PMID:35046051") obo:IAO_0000115 obo:CL_4033024 "A basal cell that is part of a duct of an airway submucosal gland.")
AnnotationAssertion(terms:contributor obo:CL_4033024 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033024 "https://orcid.org/0000-0002-9185-3994")
AnnotationAssertion(terms:date obo:CL_4033024 "2023-03-16T15:51:39Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033024 "airway submucosal gland duct basal cell")
SubClassOf(obo:CL_4033024 obo:CL_0000646)
SubClassOf(obo:CL_4033024 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410077))

# Class: obo:CL_4033025 (perichondrial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "wikipedia:Perichondrium") obo:IAO_0000115 obo:CL_4033025 "A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production.")
AnnotationAssertion(terms:contributor obo:CL_4033025 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033025 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033025 "2023-03-16T16:12:50Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033025 "perichondrial fibroblast")
EquivalentClasses(obo:CL_4033025 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008305)))

# Class: obo:CL_4033026 (lung perichondrial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36543915") obo:IAO_0000115 obo:CL_4033026 "A perichondrial fibroblast that is part of the lung.")
AnnotationAssertion(terms:contributor obo:CL_4033026 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033026 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033026 "2023-03-16T16:15:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36543915") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033026 "PC-fibro")
AnnotationAssertion(rdfs:label obo:CL_4033026 "lung perichondrial fibroblast")
EquivalentClasses(obo:CL_4033026 ObjectIntersectionOf(obo:CL_4033025 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))

# Class: obo:CL_4033027 (diffuse bipolar 1 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22006647") obo:IAO_0000115 obo:CL_4033027 "An OFF diffuse bipolar cell that makes synaptic contact with both L/M and S-cone photoreceptors and only minimal contact with rod photoreceptors.")
AnnotationAssertion(terms:contributor obo:CL_4033027 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033027 "2023-04-04T10:48:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22006647") oboInOwl:hasExactSynonym obo:CL_4033027 "Diffuse Bipolar Cell Type DB1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22006647") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033027 "DB1 bipolar")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22006647") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033027 "DB1 bipolar cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033027 "DB1 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22006647") Annotation(oboInOwl:hasDbXref "PMID:32032773") rdfs:comment obo:CL_4033027 "In primates, a diffuse bipolar 1 cell on average makes 81 ribbon (output) synapses, 13 contacts are with OFF parasol cells and 47 contacts are with OFF midget cells. This cell might make flat contacts at both triad-associated and non-triad-associated positions on the cone pedicle.")
AnnotationAssertion(rdfs:label obo:CL_4033027 "diffuse bipolar 1 cell")
SubClassOf(obo:CL_4033027 obo:CL_0000750)

# Class: obo:CL_4033028 (diffuse bipolar 2 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25309346") Annotation(oboInOwl:hasDbXref "PMID:26500507") Annotation(oboInOwl:hasDbXref "PMID:27833534") obo:IAO_0000115 obo:CL_4033028 "An OFF diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. This cell contains a large number of synaptic ribbons and a small axon arbor area.")
AnnotationAssertion(terms:contributor obo:CL_4033028 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033028 "2023-04-04T10:49:07Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033028 "DB2 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") rdfs:comment obo:CL_4033028 "In primates, a diffuse bipolar 2 cell makes an average of 133 ribbon synapses, 47 contacts are with OFF parasol cells and 4 contacts are with OFF midget cells.")
AnnotationAssertion(rdfs:label obo:CL_4033028 "diffuse bipolar 2 cell")
SubClassOf(obo:CL_4033028 obo:CL_0000750)

# Class: obo:CL_4033029 (diffuse bipolar 3a cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") Annotation(oboInOwl:hasDbXref "PMID:33009001") obo:IAO_0000115 obo:CL_4033029 "An OFF calbindin-positive bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3a contacts with cones are triad-associated.")
AnnotationAssertion(terms:contributor obo:CL_4033029 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033029 "2023-04-04T10:53:33Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fnana.2015.00122") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033029 "DB3 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033029 "DB3a cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fnana.2015.00122") Annotation(oboInOwl:hasDbXref "PMID:32032773") rdfs:comment obo:CL_4033029 "Originally, DB3a cells were termed diffuse bipolar 3 (DB3) cells. When an additional bipolar type which stratifies slightly more vitread and is calbindin negative was detected, this cell was renamed diffuse bipolar 3a cell. The axons of neighboring DB3a cells make homologous gap junctions. The DB3a cells provide the majority of their output to OFF parasol cells.")
AnnotationAssertion(rdfs:label obo:CL_4033029 "diffuse bipolar 3a cell")
SubClassOf(obo:CL_4033029 obo:CL_0000750)

# Class: obo:CL_4033030 (diffuse bipolar 3b cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033030 "An OFF calbindin-negative bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3b contacts with cones are non-triad-associated.")
AnnotationAssertion(terms:contributor obo:CL_4033030 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033030 "2023-04-04T10:53:42Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033030 "DB3b cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24107939") Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:33009001") rdfs:comment obo:CL_4033030 "In humans, a DB3b cell is CD15 positive. A DB3b cell might make sparse contacts to rod photoreceptors.")
AnnotationAssertion(rdfs:label obo:CL_4033030 "diffuse bipolar 3b cell")
SubClassOf(obo:CL_4033030 obo:CL_0000750)

# Class: obo:CL_4033031 (diffuse bipolar 4 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27833534") Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033031 "An ON diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells.")
AnnotationAssertion(terms:contributor obo:CL_4033031 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033031 "2023-04-04T09:51:10Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033031 "DB4 cell")
AnnotationAssertion(rdfs:label obo:CL_4033031 "diffuse bipolar 4 cell")
SubClassOf(obo:CL_4033031 obo:CL_0000749)

# Class: obo:CL_4033032 (diffuse bipolar 6 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033032 "An ON diffuse bipolar cell that has a large dendritic field and large axon terminals, which show little or no overlap. This cell predominantly connects to narrow thorny ganglion cells.")
AnnotationAssertion(terms:contributor obo:CL_4033032 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033032 "2023-04-04T09:51:22Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033032 "DB6 cell")
AnnotationAssertion(rdfs:label obo:CL_4033032 "diffuse bipolar 6 cell")
SubClassOf(obo:CL_4033032 obo:CL_0000749)

# Class: obo:CL_4033033 (flat midget bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033033 "An OFF bipolar cell with a small dendritic tree that provides most of the triad-associated basal (flat) contacts at cone pedicles.")
AnnotationAssertion(terms:contributor obo:CL_4033033 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033033 "2023-04-04T10:54:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033033 "FMB cell")
AnnotationAssertion(rdfs:label obo:CL_4033033 "flat midget bipolar cell")
SubClassOf(obo:CL_4033033 obo:CL_0000750)

# Class: obo:CL_4033034 (invaginating midget bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033034 "An ON bipolar cell with a small dendritic tree that forms most of the central (invaginating) elements opposite the synaptic ribbon at the cone triad.")
AnnotationAssertion(terms:contributor obo:CL_4033034 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033034 "2023-04-04T09:51:44Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033034 "IMB cell")
AnnotationAssertion(rdfs:label obo:CL_4033034 "invaginating midget bipolar cell")
SubClassOf(obo:CL_4033034 obo:CL_0000749)

# Class: obo:CL_4033035 (giant bipolar cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033035 "An ON bipolar cell that has large dendritic and axonal fields.")
AnnotationAssertion(terms:contributor obo:CL_4033035 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033035 "2023-04-04T09:54:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033035 "GB cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") rdfs:comment obo:CL_4033035 "A giant bipolar cell is usually monostratified, although, very rarely, it can be bistratified.")
AnnotationAssertion(rdfs:label obo:CL_4033035 "giant bipolar cell")
SubClassOf(obo:CL_4033035 obo:CL_0000749)

# Class: obo:CL_4033036 (OFFx cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30712875") Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "PMID:32555229") obo:IAO_0000115 obo:CL_4033036 "An OFF bipolar cell that is fovea-specific and expresses FEZF1, NXPH1 and NXPH2.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4033036 obo:NCBITaxon_9443)
AnnotationAssertion(terms:contributor obo:CL_4033036 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033036 "2023-04-04T10:54:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033036 "OFFx cell")
SubClassOf(obo:CL_4033036 obo:CL_0000750)
SubClassOf(obo:CL_4033036 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001786))

# Class: obo:CL_4033037 (mucus secreting cell of tracheobronchial tree submucosal gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30864819") obo:IAO_0000115 obo:CL_4033037 "A mucus secreting cell of a submucosal gland of the tracheobronchial tree.")
AnnotationAssertion(terms:contributor obo:CL_4033037 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033037 "2023-04-20T10:55:50Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033037 "mucus secreting cell of tracheobronchial tree submucosal gland")
EquivalentClasses(obo:CL_4033037 ObjectIntersectionOf(obo:CL_0000319 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0007196) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410077)))
SubClassOf(obo:CL_4033037 obo:CL_0002202)

# Class: obo:CL_4033038 (lung resident memory CD4-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24064670") Annotation(oboInOwl:hasDbXref "PMID:31265968") obo:IAO_0000115 obo:CL_4033038 "An alpha-beta CD4 T cell that resides in the lung.")
AnnotationAssertion(terms:contributor obo:CL_4033038 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033038 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033038 "2023-04-27T10:15:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24064670") oboInOwl:hasExactSynonym obo:CL_4033038 "lung resident memory CD4 T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31265968") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033038 "lung CD4-positive TRM")
AnnotationAssertion(rdfs:label obo:CL_4033038 "lung resident memory CD4-positive, alpha-beta T cell")
SubClassOf(obo:CL_4033038 obo:CL_0000897)
SubClassOf(obo:CL_4033038 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048))

# Class: obo:CL_4033039 (lung resident memory CD8-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28418771") Annotation(oboInOwl:hasDbXref "PMID:31265968") obo:IAO_0000115 obo:CL_4033039 "An alpha-beta CD8 T cell that resides in the lung.")
AnnotationAssertion(terms:contributor obo:CL_4033039 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033039 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033039 "2023-04-27T10:16:07Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31265968") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033039 "lung CD8-positive TRM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31558615") rdfs:comment obo:CL_4033039 "In the lung, CXCR6 regulates the localization of lung resident memory CD8-positive, alpha-beta T cells.")
AnnotationAssertion(rdfs:label obo:CL_4033039 "lung resident memory CD8-positive, alpha-beta T cell")
SubClassOf(obo:CL_4033039 obo:CL_0000909)
SubClassOf(obo:CL_4033039 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048))

# Class: obo:CL_4033040 (lung resident memory CD8-positive, CD103-positive, alpha-beta T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27776108") obo:IAO_0000115 obo:CL_4033040 "A lung resident memory CD8-positive, alpha-beta T cell that is CD103-positive.")
AnnotationAssertion(terms:contributor obo:CL_4033040 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033040 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033040 "2023-05-24T12:23:35Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27776108") oboInOwl:hasExactSynonym obo:CL_4033040 "lung TRM CD8-positive, CD103-positive cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27776108") oboInOwl:hasExactSynonym obo:CL_4033040 "lung TRM CD8-positive, integrin alpha E-positive cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27776108") oboInOwl:hasExactSynonym obo:CL_4033040 "lung resident memory CD8-positive CD103-positive, alpha-beta T cell")
AnnotationAssertion(rdfs:label obo:CL_4033040 "lung resident memory CD8-positive, CD103-positive, alpha-beta T cell")
EquivalentClasses(obo:CL_4033040 ObjectIntersectionOf(obo:CL_4033039 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001010)))

# Class: obo:CL_4033041 (CCL3-positive alveolar macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") obo:IAO_0000115 obo:CL_4033041 "An alveolar macrophage that expresses CCL3.")
AnnotationAssertion(terms:contributor obo:CL_4033041 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033041 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033041 "2023-06-15T12:53:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") oboInOwl:hasExactSynonym obo:CL_4033041 "alveolar macrophage CCL3-positive")
AnnotationAssertion(rdfs:label obo:CL_4033041 "CCL3-positive alveolar macrophage")
SubClassOf(obo:CL_4033041 obo:CL_0000583)
SubClassOf(obo:CL_4033041 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000002123))

# Class: obo:CL_4033042 (metallothionein-positive alveolar macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") obo:IAO_0000115 obo:CL_4033042 "An alveolar macrophage that expresses metallothionein.")
AnnotationAssertion(terms:contributor obo:CL_4033042 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033042 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033042 "2023-06-15T12:55:34Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") oboInOwl:hasExactSynonym obo:CL_4033042 "alveolar macrophage MT-positive")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") oboInOwl:hasExactSynonym obo:CL_4033042 "alveolar macrophage metallothionein-positive")
AnnotationAssertion(rdfs:label obo:CL_4033042 "metallothionein-positive alveolar macrophage")
SubClassOf(obo:CL_4033042 obo:CL_0000583)

# Class: obo:CL_4033043 (lung interstitial macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33382972") Annotation(oboInOwl:hasDbXref "PMID:35017701") Annotation(oboInOwl:hasDbXref "PMID:36211428") obo:IAO_0000115 obo:CL_4033043 "A macrophage that is part of the lung connective tissue (pulmonary interstitium). This cell performs tissue remodeling and contributes to barrier immunity through antigen presentation.")
AnnotationAssertion(terms:contributor obo:CL_4033043 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033043 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033043 "2023-06-15T12:58:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36211428") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033043 "lung IM")
AnnotationAssertion(rdfs:label obo:CL_4033043 "lung interstitial macrophage")
SubClassOf(obo:CL_4033043 obo:CL_0000235)
SubClassOf(obo:CL_4033043 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000114))

# Class: obo:CL_4033044 (deuterosomal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31558434") Annotation(oboInOwl:hasDbXref "PMID:331922198") Annotation(oboInOwl:hasDbXref "PMID:36883528") Annotation(oboInOwl:hasDbXref "PMID:37291214") obo:IAO_0000115 obo:CL_4033044 "An epithelial cell part of respiratory tract epithelium that is a precursor of a multi-ciliated cell. This cell actively amplifies centrioles, a required step for multiciliogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4033044 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033044 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033044 "2023-06-20T10:27:17Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31558434") Annotation(oboInOwl:hasDbXref "PMID:331922198") Annotation(oboInOwl:hasDbXref "PMID:36883528") rdfs:comment obo:CL_4033044 "In humans, deuterosomal cells have been noted to have enriched expression of the following: PLK4, FOXJ1, DEUP1, FOXN4, YPEL1, HES6 and CDC20B. Deuterosomal cells were termed after deuterosomes, the platforms of active centriole amplification.")
AnnotationAssertion(rdfs:label obo:CL_4033044 "deuterosomal cell")
SubClassOf(obo:CL_4033044 obo:CL_0000066)
SubClassOf(obo:CL_4033044 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802))
SubClassOf(obo:CL_4033044 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0098535))

# Class: obo:CL_4033045 (lung migratory dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34516781") obo:IAO_0000115 obo:CL_4033045 "A dendritic cell that captures antigens in a lung and migrates to a lymph node or to the spleen to activate T cells.")
AnnotationAssertion(terms:contributor obo:CL_4033045 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033045 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033045 "2023-06-21T10:04:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34516781") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033045 "lung mDC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34516781") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4033045 "lung mDCs")
AnnotationAssertion(rdfs:label obo:CL_4033045 "lung migratory dendritic cell")
SubClassOf(obo:CL_4033045 obo:CL_0000451)

# Class: obo:CL_4033046 (ON midget ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033046 "A midget ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from invaginating midget bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033046 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033046 "2023-08-08T09:40:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033046 "ON-midget RGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033046 "ON-midget cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasExactSynonym obo:CL_4033046 "inner stratifying midget cell")
AnnotationAssertion(rdfs:label obo:CL_4033046 "ON midget ganglion cell")
EquivalentClasses(obo:CL_4033046 ObjectIntersectionOf(obo:CL_4023032 obo:CL_4023188))

# Class: obo:CL_4033047 (OFF midget ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033047 "A midget ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from flat midget bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033047 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033047 "2023-08-08T11:05:37Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033047 "OFF-midget RGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033047 "OFF-midget cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasExactSynonym obo:CL_4033047 "outer stratifying midget cell")
AnnotationAssertion(rdfs:label obo:CL_4033047 "OFF midget ganglion cell")
EquivalentClasses(obo:CL_4033047 ObjectIntersectionOf(obo:CL_4023033 obo:CL_4023188))

# Class: obo:CL_4033048 (respiratory tract suprabasal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25564622") Annotation(oboInOwl:hasDbXref "PMID:34044844") Annotation(oboInOwl:hasDbXref "PMID:35387001") Annotation(oboInOwl:hasDbXref "PMID:37834236") obo:IAO_0000115 obo:CL_4033048 "A respiratory epithelial cell derived from a basal cell, with a topographic nuclear position between the basal and luminal cells of the airway epithelium. This non-basal, intermediate progenitor cell has limited proliferative capacity and can differentiate into multiciliated, secretory, or rare airway cells (ionocytes, tuft cells, neuroendocrine cells). It shares some ultrastructural features with basal cells but lacks the defined characteristics of fully differentiated cellular phenotypes.")
AnnotationAssertion(terms:contributor obo:CL_4033048 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033048 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033048 "2023-06-20T10:44:30Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25564622") oboInOwl:hasExactSynonym obo:CL_4033048 "respiratory parabasal cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4033048 "respiratory suprabasal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25658372") oboInOwl:hasExactSynonym obo:CL_4033048 "respiratory suprabasal progenitor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25658372") Annotation(oboInOwl:hasDbXref "PMID:32726565") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.04.20.537495") rdfs:comment obo:CL_4033048 "In humans, respiratory tract suprabasal cells have been noted to have enriched expression of the following: CK8, KRT13, IVL, and SERPINB3. Single-cell sequencing indicates that suprabasal cells derived from the nasal epithelium are distinct from those in the tracheobronchial epithelium.")
AnnotationAssertion(rdfs:label obo:CL_4033048 "respiratory tract suprabasal cell")
SubClassOf(obo:CL_4033048 obo:CL_0011026)
SubClassOf(obo:CL_4033048 obo:CL_7770004)
SubClassOf(obo:CL_4033048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004802))
SubClassOf(obo:CL_4033048 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002633))

# Class: obo:CL_4033049 (taste receptor cell of tongue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1111/j.1096-3642.1981.tb01137.x") Annotation(oboInOwl:hasDbXref "PMID:10052456") Annotation(oboInOwl:hasDbXref "PMID:28655883") Annotation(oboInOwl:hasDbXref "http://www.nejohnston.org/Birds/documents/AvianTongues_Johnston.pdf") obo:IAO_0000115 obo:CL_4033049 "A taste receptor cell that is part of a taste bud of a tongue.")
AnnotationAssertion(terms:contributor obo:CL_4033049 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033049 "2023-05-03T07:59:58Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/s0022-5320(69)80043-2") oboInOwl:hasRelatedSynonym obo:CL_4033049 "gustatory cell of tongue")
AnnotationAssertion(rdfs:label obo:CL_4033049 "taste receptor cell of tongue")
EquivalentClasses(obo:CL_4033049 ObjectIntersectionOf(obo:CL_0000209 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014451)))

# Class: obo:CL_4033050 (catecholaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0521442516") Annotation(oboInOwl:hasDbXref "PMID:12094209") obo:IAO_0000115 obo:CL_4033050 "A neuron that releases catecholamine as a neurotransmitter.")
AnnotationAssertion(terms:contributor obo:CL_4033050 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033050 "2023-05-18T12:07:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10191060") Annotation(oboInOwl:hasDbXref "PMID:12128258") Annotation(oboInOwl:hasDbXref "PMID:34880760") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2244-7917") rdfs:comment obo:CL_4033050 "Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis.")
AnnotationAssertion(rdfs:label obo:CL_4033050 "catecholaminergic neuron")
EquivalentClasses(obo:CL_4033050 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0160043)))

# Class: obo:CL_4033051 (OFF parasol ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033051 "A parasol ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB3a bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033051 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033051 "2023-08-08T12:34:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033051 "OFF-parasol RGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033051 "OFF-parasol retinal ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasExactSynonym obo:CL_4033051 "outer parasol cell")
AnnotationAssertion(rdfs:label obo:CL_4033051 "OFF parasol ganglion cell")
EquivalentClasses(obo:CL_4033051 ObjectIntersectionOf(obo:CL_4023033 obo:CL_4023189))

# Class: obo:CL_4033052 (ON parasol ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033052 "A parasol ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB4 bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033052 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033052 "2023-08-08T12:39:35Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033052 "ON-parasol RGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") oboInOwl:hasExactSynonym obo:CL_4033052 "ON-parasol retinal ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasExactSynonym obo:CL_4033052 "inner parasol cell")
AnnotationAssertion(rdfs:label obo:CL_4033052 "ON parasol ganglion cell")
EquivalentClasses(obo:CL_4033052 ObjectIntersectionOf(obo:CL_4023032 obo:CL_4023189))

# Class: obo:CL_4033053 (small bistratified retinal ganglion cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033053 "A bistratfied retinal ganglion cell with a small dendritic field that has dendrites in the ON and OFF sublamina of the retinal inner plexiform layer and carries blue-ON/yellow-OFF signals. This cell receives bipolar and amacrine input to both the OFF and ON dendritic tree.")
AnnotationAssertion(terms:contributor obo:CL_4033053 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033053 "2023-08-08T12:43:56Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasExactSynonym obo:CL_4033053 "small bistratified cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1002/cne.22183") oboInOwl:hasExactSynonym obo:CL_4033053 "small bistratified cell, blue-ON/yellow-OFF ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") oboInOwl:hasRelatedSynonym obo:CL_4033053 "Polyak's shrub cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033053 "SBS ganglion cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34093409") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033053 "sbRGC")
AnnotationAssertion(rdfs:label obo:CL_4033053 "small bistratified retinal ganglion cell")
SubClassOf(obo:CL_4033053 obo:CL_0003001)
SubClassOf(obo:CL_4033053 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001792))

# Class: obo:CL_4033054 (perivascular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24928499") Annotation(oboInOwl:hasDbXref "PMID:27889329") obo:IAO_0000115 obo:CL_4033054 "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics.")
AnnotationAssertion(terms:contributor obo:CL_4033054 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033054 "2023-08-22T13:40:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033054 "perivascular cell")
EquivalentClasses(obo:CL_4033054 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0002049)))

# Class: obo:CL_4033055 (airway submucosal gland duct multiciliated cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17707699") Annotation(oboInOwl:hasDbXref "PMID:30864819") obo:IAO_0000115 obo:CL_4033055 "A multi-ciliated epithelial cell located in ciliated duct of an airway submucosal gland, characterized by a columnar shape and motile cilia on its apical surface.")
AnnotationAssertion(terms:contributor obo:CL_4033055 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033055 <https://orcid.org/0000-0002-9185-3994>)
AnnotationAssertion(terms:date obo:CL_4033055 "2023-09-08T10:32:27Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4033055 "airway submucosal gland duct ciliated cell")
AnnotationAssertion(rdfs:label obo:CL_4033055 "airway submucosal gland duct multiciliated cell")
EquivalentClasses(obo:CL_4033055 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8410077) ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600014) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_4033056 (onychocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24079581") Annotation(oboInOwl:hasDbXref "PMID:28098391") Annotation(oboInOwl:hasDbXref "PMID:30969555") Annotation(oboInOwl:hasDbXref "PMID:34099859") Annotation(oboInOwl:hasDbXref "PMID:39451193") obo:IAO_0000115 obo:CL_4033056 "A terminally differentiated, specialized keratinocyte originating primarily from the nail matrix. During onychokeratinization, these cells undergo progressive flattening and produce high levels of hard, disulfide cross-linked keratins (Eckhart et al., 2024) that form the rigid, compact nail plate. Unlike epidermal keratinocytes, onychocytes are firmly integrated into the nail plate and do not desquamate.")
AnnotationAssertion(terms:contributor obo:CL_4033056 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033056 "2023-10-03T12:49:46Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033056 "onychocyte")
SubClassOf(obo:CL_4033056 obo:CL_0000312)
SubClassOf(obo:CL_4033056 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008198))

# Class: obo:CL_4033057 (luminal adaptive secretory precursor cell of mammary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19648928") Annotation(oboInOwl:hasDbXref "PMID:35617956") Annotation(oboInOwl:hasDbXref "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6677-8489") obo:IAO_0000115 obo:CL_4033057 "A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8.")
AnnotationAssertion(terms:contributor obo:CL_4033057 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033057 <https://orcid.org/0000-0003-4969-670X>)
AnnotationAssertion(terms:date obo:CL_4033057 "2023-10-13T13:02:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35617956") oboInOwl:hasBroadSynonym obo:CL_4033057 "alveolar cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26390871") oboInOwl:hasBroadSynonym obo:CL_4033057 "alveolar progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.04.21.537845") oboInOwl:hasBroadSynonym obo:CL_4033057 "luminal progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20346151") oboInOwl:hasBroadSynonym obo:CL_4033057 "luminal progenitor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") oboInOwl:hasBroadSynonym obo:CL_4033057 "luminal secretory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") oboInOwl:hasExactSynonym obo:CL_4033057 "ER-negative luminal alveolar progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033057 "AP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35617956") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033057 "AV")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6677-8489") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033057 "LASP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.04.21.537845") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033057 "LP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033057 "LumSec")
AnnotationAssertion(rdfs:label obo:CL_4033057 "luminal adaptive secretory precursor cell of mammary gland")
SubClassOf(obo:CL_4033057 obo:CL_0002326)
SubClassOf(obo:CL_4033057 obo:CL_0011115)

# Class: obo:CL_4033058 (luminal hormone-sensing cell of mammary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19648928") Annotation(oboInOwl:hasDbXref "PMID:26390871") Annotation(oboInOwl:hasDbXref "PMID:34156490") Annotation(oboInOwl:hasDbXref "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6677-8489") obo:IAO_0000115 obo:CL_4033058 "A luminal epithelial cell of the mammary gland that transduces endocrine cues to orchestrate proliferation, architectural remodeling, and differentiation of other cells in the mammary gland via paracrine signaling. This cell expresses high levels of estrogen receptors. In humans, a luminal hormone-sensing cell can be identified by high levels of EpCAM and low levels of CD49f, and in mice it can be identified by low levels of CD29 and high levels of Foxa1, CD133, and Sca1 (Ly6a).")
AnnotationAssertion(terms:contributor obo:CL_4033058 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033058 <https://orcid.org/0000-0003-4969-670X>)
AnnotationAssertion(terms:date obo:CL_4033058 "2023-10-16T08:30:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.04.21.537845") oboInOwl:hasBroadSynonym obo:CL_4033058 "hormone sensing cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26390871") oboInOwl:hasBroadSynonym obo:CL_4033058 "hormone-sensing mammary epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") oboInOwl:hasBroadSynonym obo:CL_4033058 "luminal hormone-responsive cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20346151") oboInOwl:hasBroadSynonym obo:CL_4033058 "luminal mature cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") oboInOwl:hasExactSynonym obo:CL_4033058 "ER-positive luminal hormone-sensor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.04.21.537845") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033058 "HS")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26390871") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033058 "HS-MEC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6677-8489") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033058 "LHS")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37380767") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033058 "LumHR")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26390871") Annotation(oboInOwl:hasDbXref "PMID:34156490") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0003-4969-670X") rdfs:comment obo:CL_4033058 "Following lineage specification, a luminal hormone-sensing cell expresses receptors for one or more hormones, such as estrogens, progesterone, androgens, and prolactin. In response to progesterone, luminal hormone-sensing cells express TNFSF11, WNT4, and RSPO1, among other factors, which cause branching, proliferation, and partial differentiation in LASP and B-Myo cells during luteal phases of the estrous/menstrual cycle and during gestation. During ductal elongation, ER activity drives expression of AREG in LHS cells, which is necessary for proliferation of the epithelium to fill the mammary fat pad.")
AnnotationAssertion(rdfs:label obo:CL_4033058 "luminal hormone-sensing cell of mammary gland")
SubClassOf(obo:CL_4033058 obo:CL_0002326)
SubClassOf(obo:CL_4033058 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000007204))

# Class: obo:CL_4033059 (lactocyte type 1)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasDbXref "PMID:35377806") obo:IAO_0000115 obo:CL_4033059 "A lactocyte that highly expresses genes associated with transcription, immune cell function, and cellular stress. A lactocyte type 1 also expresses genes involved in milk component biosynthesis (e.g., LALBA and CSNs), albeit at lower levels than a lactocyte type 2.")
AnnotationAssertion(terms:contributor obo:CL_4033059 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033059 <https://orcid.org/0000-0003-4361-817X>)
AnnotationAssertion(terms:date obo:CL_4033059 "2023-10-16T13:15:36Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34097179") oboInOwl:hasBroadSynonym obo:CL_4033059 "luminal cluster 1 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033059 "LC1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") oboInOwl:hasRelatedSynonym obo:CL_4033059 "LMC major luminal cluster 1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033059 "progenitor MEC")
AnnotationAssertion(rdfs:label obo:CL_4033059 "lactocyte type 1")
SubClassOf(obo:CL_4033059 obo:CL_0002325)

# Class: obo:CL_4033060 (lactocyte type 2)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasDbXref "PMID:35377806") obo:IAO_0000115 obo:CL_4033060 "A lactocyte that highly expresses genes associated with lipid production and milk component biosynthesis.")
AnnotationAssertion(terms:contributor obo:CL_4033060 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033060 <https://orcid.org/0000-0003-4361-817X>)
AnnotationAssertion(terms:date obo:CL_4033060 "2023-10-16T13:15:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35377806") oboInOwl:hasBroadSynonym obo:CL_4033060 "luminal cluster 2 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033060 "LC2")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35091553") oboInOwl:hasRelatedSynonym obo:CL_4033060 "LMC major luminal cluster 2")
AnnotationAssertion(rdfs:label obo:CL_4033060 "lactocyte type 2")
SubClassOf(obo:CL_4033060 obo:CL_0002325)

# Class: obo:CL_4033061 (endothelial cell of central vein of liver)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28287163") obo:IAO_0000115 obo:CL_4033061 "An endothelial cell that is part of a central vein of liver.")
AnnotationAssertion(terms:contributor obo:CL_4033061 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28287163") oboInOwl:hasBroadSynonym obo:CL_4033061 "endothelial cell of central vein")
AnnotationAssertion(rdfs:label obo:CL_4033061 "endothelial cell of central vein of liver")
EquivalentClasses(obo:CL_4033061 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006841)))

# Class: obo:CL_4033062 (interstitial extravillous trophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-84725-8") obo:IAO_0000115 obo:CL_4033062 "A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration.")
AnnotationAssertion(terms:contributor obo:CL_4033062 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033062 "2024-01-08T15:43:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-84725-8") oboInOwl:hasExactSynonym obo:CL_4033062 "invasive interstitial extravillous trophoblast cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033062 "iEVT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") oboInOwl:hasRelatedSynonym obo:CL_4033062 "interstitial extravillous trophoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11337369") oboInOwl:hasRelatedSynonym obo:CL_4033062 "interstitial trophoblast")
AnnotationAssertion(rdfs:label obo:CL_4033062 "interstitial extravillous trophoblast cell")
SubClassOf(obo:CL_4033062 obo:CL_0000351)
SubClassOf(obo:CL_4033062 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0008036))

# Class: obo:CL_4033063 (endovascular extravillous trophoblast cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-030-84725-8") obo:IAO_0000115 obo:CL_4033063 "A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56.")
AnnotationAssertion(terms:contributor obo:CL_4033063 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033063 "2024-01-08T15:43:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033063 "eEVT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") oboInOwl:hasRelatedSynonym obo:CL_4033063 "endovascular extravillous trophoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11337369") oboInOwl:hasRelatedSynonym obo:CL_4033063 "endovascular trophoblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37630754") rdfs:comment obo:CL_4033063 "Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress.")
AnnotationAssertion(rdfs:label obo:CL_4033063 "endovascular extravillous trophoblast cell")
SubClassOf(obo:CL_4033063 obo:CL_0000351)
SubClassOf(obo:CL_4033063 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0008036))

# Class: obo:CL_4033064 (uterine resident macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36113384") obo:IAO_0000115 obo:CL_4033064 "A tissue-resident macrophage that is part of the uterus.")
AnnotationAssertion(terms:contributor obo:CL_4033064 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033064 "2024-01-08T16:05:09Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36113384") oboInOwl:hasBroadSynonym obo:CL_4033064 "uterine macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36113384") rdfs:comment obo:CL_4033064 "Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands.")
AnnotationAssertion(rdfs:label obo:CL_4033064 "uterine resident macrophage")
EquivalentClasses(obo:CL_4033064 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000995)))

# Class: obo:CL_4033065 (preplasmablast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21918187") Annotation(oboInOwl:hasDbXref "PMID:30755708") Annotation(oboInOwl:hasDbXref "PMID:33150420") obo:IAO_0000115 obo:CL_4033065 "A mature B cell that serves as an intermediate stage in the differentiation of naive B cells into a plasmablast. A preplasmablast expresses CD30 and IL-6R and lacks expression of CD20, CD23, CD38 and CD138.")
AnnotationAssertion(terms:contributor obo:CL_4033065 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033065 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033065 "2024-04-25T09:14:58Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23613519") oboInOwl:hasExactSynonym obo:CL_4033065 "pre-plasmablast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33661294") oboInOwl:hasExactSynonym obo:CL_4033065 "preplasmablastic cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21918187") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033065 "prePB")
AnnotationAssertion(rdfs:label obo:CL_4033065 "preplasmablast")
SubClassOf(obo:CL_4033065 obo:CL_0000785)
SubClassOf(obo:CL_4033065 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000788))
SubClassOf(obo:CL_4033065 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000980))

# Class: obo:CL_4033066 (pre-granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17639032") Annotation(oboInOwl:hasDbXref "PMID:32759216") Annotation(oboInOwl:hasDbXref "PMID:33970370") Annotation(oboInOwl:hasDbXref "PMID:38178246") obo:IAO_0000115 obo:CL_4033066 "A supporting cell that is part of the ovary and differentiates into a granulosa cell. A pre-granulosa cell develops from an early supporting gonadal cell by repressing testis determination, which can then proliferate to form primordial follicles.")
AnnotationAssertion(terms:contributor obo:CL_4033066 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033066 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033066 "2024-06-07T12:04:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32759216") oboInOwl:hasExactSynonym obo:CL_4033066 "ovarian pregranulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17639032") Annotation(oboInOwl:hasDbXref "PMID:32759216") oboInOwl:hasExactSynonym obo:CL_4033066 "pregranulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32759216") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033066 "PG cell")
AnnotationAssertion(rdfs:label obo:CL_4033066 "pre-granulosa cell")
SubClassOf(obo:CL_4033066 obo:CL_0000630)
SubClassOf(obo:CL_4033066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992))
SubClassOf(obo:CL_4033066 ObjectSomeValuesFrom(obo:RO_0002210 obo:CL_4033083))

# Class: obo:CL_4033067 (mural granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27815559") Annotation(oboInOwl:hasDbXref "PMID:33970370") Annotation(oboInOwl:hasDbXref "PMID:34198768") obo:IAO_0000115 obo:CL_4033067 "A follicular cell of ovary that differentiates from a cuboidal granulosa cell during the secondary follicle stage. Mural granulosa cells line the inner surface of the follicle wall, surrounding the fluid-filled antral cavity. These cells produce oestrogen during the follicular phase in response to follicle-stimulating hormone (FSH), and progesterone after ovulation in response to luteinizing hormone (LH).")
AnnotationAssertion(terms:contributor obo:CL_4033067 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033067 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033067 "2024-06-07T12:15:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4033067 "EFO:0005289")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1530/REP-16-0500") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033067 "MGC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34198768") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033067 "mural GC")
AnnotationAssertion(rdfs:label obo:CL_4033067 "mural granulosa cell")
SubClassOf(obo:CL_4033067 obo:CL_0000501)
SubClassOf(obo:CL_4033067 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000992))
SubClassOf(obo:CL_4033067 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4033084))

# Class: obo:CL_4033083 (squamous granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28892263") obo:IAO_0000115 obo:CL_4033083 "A granulosa cell that has a squamous morphology and form a single layer around the oocyte in primordial follicles. This cell develops directly into a cuboidal granulosa cell during the primordial-to-primary follicle transition.")
AnnotationAssertion(terms:contributor obo:CL_4033083 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033083 "2024-09-24T13:13:24Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22402964") oboInOwl:hasExactSynonym obo:CL_4033083 "flattened granulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33914868") oboInOwl:hasRelatedSynonym obo:CL_4033083 "pre-granulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33914868") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033083 "squamous GC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-6677-8489") rdfs:comment obo:CL_4033083 "Often in literature squamous granulosa cell and pre-granulosa cell are used as synonyms. However, this term only makes reference to the quiescent granulosa cells that surround the primordial ovarian follicle, while a pre-granulosa cell proliferates to form the primordial follicle (and thus cells become the squamous granulosa cells).")
AnnotationAssertion(rdfs:label obo:CL_4033083 "squamous granulosa cell")
SubClassOf(obo:CL_4033083 obo:CL_0000501)
SubClassOf(obo:CL_4033083 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003981))
SubClassOf(obo:CL_4033083 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4033066))
SubClassOf(obo:CL_4033083 ObjectSomeValuesFrom(obo:RO_0002210 obo:CL_4033084))

# Class: obo:CL_4033084 (cuboidal granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28892263") obo:IAO_0000115 obo:CL_4033084 "A granulosa cell that has a cuboidal morphology and develops from squamous granulosa cell during the transition between primordial follicle to primary follicle. Cuboidal granulosa cells proliferate to form a second layer within secondary follicles.")
AnnotationAssertion(terms:contributor obo:CL_4033084 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033084 "2024-09-24T13:14:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19001500") oboInOwl:hasExactSynonym obo:CL_4033084 "columnar granulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31849844") oboInOwl:hasExactSynonym obo:CL_4033084 "cuboidal epithelial granulosa cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19001500") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033084 "columnar GC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33914868") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033084 "cuboidal GC")
AnnotationAssertion(rdfs:label obo:CL_4033084 "cuboidal granulosa cell")
SubClassOf(obo:CL_4033084 obo:CL_0000501)
SubClassOf(obo:CL_4033084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001305))
SubClassOf(obo:CL_4033084 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4033083))

# Class: obo:CL_4033085 (diffuse bipolar 5 cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27833534") Annotation(oboInOwl:hasDbXref "PMID:32032773") obo:IAO_0000115 obo:CL_4033085 "An ON diffuse bipolar cell that stratifies in the stratum 3 of the inner plexiform layer to make synapses with ON parasol ganglion cells. A diffuse bipolar 5 cell has high expression of MYO16 compared with other bipolar cells.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4033085 obo:NCBITaxon_9443)
AnnotationAssertion(terms:contributor obo:CL_4033085 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033085 "2024-10-16T12:46:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32032773") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033085 "DB5 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27833534") rdfs:comment obo:CL_4033085 "A diffuse bipolar 5 cell typically contacts 7–8 cone photoreceptors. The number and thickness of its dendritic processes are intermediate between those of a diffuse bipolar 6 cell (less dense and thinner) and a diffuse bipolar 4 cell (denser and thicker).")
AnnotationAssertion(rdfs:label obo:CL_4033085 "diffuse bipolar 5 cell")
SubClassOf(obo:CL_4033085 obo:CL_0000749)

# Class: obo:CL_4033086 (lipid-associated macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31257031") Annotation(oboInOwl:hasDbXref "PMID:34876704") Annotation(oboInOwl:hasDbXref "PMID:35712121") obo:IAO_0000115 obo:CL_4033086 "A tissue-resident macrophage that is associated with lipids. This cell responsible of anti-inflammatory functions, lipid accumulation and enhancing phagocytosis (Wculek et al., 2022, Liu et al., 2022). In mice and humans, a lipid-associated macrophage is characterized by the marker Trem2 (Jaitlin et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4033086 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033086 <https://orcid.org/0000-0001-8134-3037>)
AnnotationAssertion(terms:date obo:CL_4033086 "2024-10-17T10:20:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31257031") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033086 "LAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35021063") Annotation(oboInOwl:hasDbXref "PMID:37153549") rdfs:comment obo:CL_4033086 "Distinct from “adipose macrophage” in Trem2 expression, and is not limited to adipose tissue. Guilliams et al. describe these cells as being distinct from Kupffer cells.")
AnnotationAssertion(rdfs:label obo:CL_4033086 "lipid-associated macrophage")
SubClassOf(obo:CL_4033086 obo:CL_0000235)
SubClassOf(obo:CL_4033086 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000016626))

# Class: obo:CL_4033087 (placental resident macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") obo:IAO_0000115 obo:CL_4033087 "A tissue-resident macrophage that is part of the placenta. This cell helps preventing immunological rejection of the fetus by modulating the immune environment. A placental resident macrophage has high plasticity to adapt to the changing needs of each phase of pregnancy.")
AnnotationAssertion(terms:contributor obo:CL_4033087 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033087 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033087 "2024-10-31T10:24:21Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") oboInOwl:hasBroadSynonym obo:CL_4033087 "placental macrophage")
AnnotationAssertion(rdfs:label obo:CL_4033087 "placental resident macrophage")
EquivalentClasses(obo:CL_4033087 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001987)))

# Class: obo:CL_4033088 (decidual resident macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") obo:IAO_0000115 obo:CL_4033088 "A resident macrophage that is part of the decidua. Some decidual macrophages are derived from maternal blood monocytes that are recruited to the uterus shortly after conception. The main functions of a decidual macrophage are implantation, placental development, immune regulation and vascular remodeling.")
AnnotationAssertion(terms:contributor obo:CL_4033088 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033088 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033088 "2024-10-31T10:33:04Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") oboInOwl:hasBroadSynonym obo:CL_4033088 "decidual macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39007150") oboInOwl:hasBroadSynonym obo:CL_4033088 "maternal decidual macrophage")
AnnotationAssertion(rdfs:label obo:CL_4033088 "decidual resident macrophage")
SubClassOf(obo:CL_4033088 obo:CL_4033087)
SubClassOf(obo:CL_4033088 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002450))

# Class: obo:CL_4033089 (atretic follicular cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38069168") obo:IAO_0000115 obo:CL_4033089 "A follicular cell of ovary that has begun to degenerate and undergo atresia, a specialized apoptosis. This cell is found in an atretic follicle, which is an ovarian follicle that started to mature but failed to reach full development and instead regresses.")
AnnotationAssertion(terms:contributor obo:CL_4033089 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033089 "2024-11-05T11:23:25Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033089 "atretic follicular cell of ovary")
EquivalentClasses(obo:CL_4033089 ObjectIntersectionOf(obo:CL_0002174 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0001552)))

# Class: obo:CL_4033090 (atretic granulosa cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15353131") Annotation(oboInOwl:hasDbXref "PMID:38069168") obo:IAO_0000115 obo:CL_4033090 "A granulosa cell that is undergoing atresia. This cell type displays distinct morphological alterations compared with a healthy granulosa cell, including pyknosis (nuclear condensation) and cellular shrinkage.")
AnnotationAssertion(terms:contributor obo:CL_4033090 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033090 "2024-11-05T11:25:28Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15353131") oboInOwl:hasRelatedSynonym obo:CL_4033090 "apoptotic granulosa cell")
AnnotationAssertion(rdfs:label obo:CL_4033090 "atretic granulosa cell")
SubClassOf(obo:CL_4033090 obo:CL_4033089)
SubClassOf(obo:CL_4033090 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000501))

# Class: obo:CL_4033091 (glycinergic-GABAergic amacrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37124720") obo:IAO_0000115 obo:CL_4033091 "An amacrine cell that uses both GABA and glycine as neurotransmitters.")
AnnotationAssertion(terms:contributor obo:CL_4033091 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033091 "2024-12-02T13:44:17Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37124720") oboInOwl:hasExactSynonym obo:CL_4033091 "glycinergic/GABAergic amacrine neuron")
AnnotationAssertion(rdfs:label obo:CL_4033091 "glycinergic-GABAergic amacrine cell")
EquivalentClasses(obo:CL_4033091 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061537)))

# Class: obo:CL_4033092 (CD57-positive enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37468586") obo:IAO_0000115 obo:CL_4033092 "An enterocyte that is part of a duodenal epithelium and expresses beta-1,3-glucuronyltransferase 1 (B3GAT1), also known as CD57 or HNK-1.")
AnnotationAssertion(terms:contributor obo:CL_4033092 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033092 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:contributor obo:CL_4033092 <https://orcid.org/0000-0001-9961-7673>)
AnnotationAssertion(terms:date obo:CL_4033092 "2024-12-06T14:32:49Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37468586") oboInOwl:hasExactSynonym obo:CL_4033092 "CD57+ enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37468586") rdfs:comment obo:CL_4033092 "While CD57 is traditionally associated with immune cells (e.g., NK cells), its expression on enterocytes marks unique epithelial subsets with specific functions or maturation states. These cells are specially enriched in areas of the duodenum within submucosal glands.")
AnnotationAssertion(rdfs:label obo:CL_4033092 "CD57-positive enterocyte")
EquivalentClasses(obo:CL_4033092 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001440)))

# Class: obo:CL_4033093 (limbal epithelial stem cell of cornea)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20614614") Annotation(oboInOwl:hasDbXref "PMID:29105366") Annotation(oboInOwl:hasDbXref "PMID:36983561") Annotation(oboInOwl:hasDbXref "PMID:37768272") obo:IAO_0000115 obo:CL_4033093 "A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023).")
AnnotationAssertion(terms:contributor obo:CL_4033093 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033093 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033093 "2024-12-11T13:59:19Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20614614") oboInOwl:hasExactSynonym obo:CL_4033093 "limbal epithelial stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17562792") oboInOwl:hasExactSynonym obo:CL_4033093 "limbal stem cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20614614") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033093 "LESC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36983561") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033093 "LSC")
AnnotationAssertion(rdfs:label obo:CL_4033093 "limbal epithelial stem cell of cornea")
EquivalentClasses(obo:CL_4033093 ObjectIntersectionOf(obo:CL_0000034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006761)))
SubClassOf(obo:CL_4033093 obo:CL_0000036)
SubClassOf(obo:CL_4033093 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000482))
SubClassOf(obo:CL_4033093 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000575))

# Class: obo:CL_4033094 (age-associated B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30873171") Annotation(oboInOwl:hasDbXref "PMID:31986068") Annotation(oboInOwl:hasDbXref "PMID:35298565") Annotation(oboInOwl:hasDbXref "PMID:35798993") obo:IAO_0000115 obo:CL_4033094 "A transcriptionally distinct memory B cell whose presence increases with age, during infections, and in autoimmune diseases. In humans and mice, this cell type can be identified by the expression of T-bet, CD11c, CD11b, and the lack of CD21. An age-associated B cell responds to TLR stimuli, may produce autoantibodies, and participates in antiviral responses and pathogen clearance.")
AnnotationAssertion(terms:contributor obo:CL_4033094 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033094 <https://orcid.org/0000-0001-7655-4833>)
AnnotationAssertion(terms:date obo:CL_4033094 "2025-01-08T14:44:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35798993") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033094 "ABC")
AnnotationAssertion(rdfs:label obo:CL_4033094 "age-associated B cell")
SubClassOf(obo:CL_4033094 obo:CL_0000787)

# Class: obo:CL_4033095 (diffuse bipolar 4a cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033095 "An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033095 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033095 "2025-01-14T13:48:42Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033095 "DB4a")
AnnotationAssertion(rdfs:label obo:CL_4033095 "diffuse bipolar 4a cell")
SubClassOf(obo:CL_4033095 obo:CL_0000749)
SubClassOf(obo:CL_4033095 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4033096 (diffuse bipolar 4b cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033096 "An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033096 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033096 "2025-01-14T13:49:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033096 "DB4b")
AnnotationAssertion(rdfs:label obo:CL_4033096 "diffuse bipolar 4b cell")
SubClassOf(obo:CL_4033096 obo:CL_0000749)
SubClassOf(obo:CL_4033096 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4033097 (Schlemm's canal endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25051267") Annotation(oboInOwl:hasDbXref "PMID:25223880") obo:IAO_0000115 obo:CL_4033097 "A specialised endothelial cell that is part of the canal of Schlemm. This cell type shares characteristics and expresses markers of both blood and lymphatic endothelial cells (Kizhatil et al., 2014) and regulates aqueous humor outflow resistance by modulating pore formation and responding to mechanical strain (Stamer et al., 2015).")
AnnotationAssertion(terms:contributor obo:CL_4033097 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033097 "2025-06-16T13:55:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25051267") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033097 "SC endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25051267") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033097 "SEC")
AnnotationAssertion(rdfs:label obo:CL_4033097 "Schlemm's canal endothelial cell")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:26402712") Annotation(rdfs:comment "Schematic of the conventional outflow pathway, showing the Schlemm's canal (SC, green) and the trabecular meshwork (TM, orange). The left inset shows an expanded view of the Schlemm’s canal’s microanatomy detailing the cell morphology of the inner and outer wall endocrine cells.") foaf:depiction obo:CL_4033097 "http://purl.obolibrary.org/obo/cl/images/Schlemms_canal_endo_cell_PMID26402712.png"^^xsd:anyURI)
EquivalentClasses(obo:CL_4033097 ObjectIntersectionOf(obo:CL_0000115 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004029)))

# Class: obo:CL_4033098 (inner wall Schlemm's canal endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15454474") Annotation(oboInOwl:hasDbXref "PMID:26402712") obo:IAO_0000115 obo:CL_4033098 "A Schlemm's canal endothelial cell that lines the inner wall of the Schlemm's canal. This cell exhibits a cobblestone appearance due to the significant biomechanical load it experiences, as well as the segmental flow of aqueous humor. The degree of biomechanical stress can lead to the formation of dome-like outpouchings known as giant vacuoles. In addition, the cell contains transcellular pores that mediate aqueous humor transport (Dautriche et al., 2015). This endothelial cell also displays prominent peripheral F-actin bands which help maintain structural integrity under pressure (Ethier et al., 2004).")
AnnotationAssertion(terms:contributor obo:CL_4033098 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033098 "2025-06-17T13:33:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26402712") oboInOwl:hasNarrowSynonym obo:CL_4033098 "human Schlemm's canal inner wall cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26402712") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033098 "HSCIW cell")
AnnotationAssertion(rdfs:label obo:CL_4033098 "inner wall Schlemm's canal endothelial cell")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:26402712") Annotation(rdfs:comment "Schematic of the conventional outflow pathway, showing the Schlemm's canal (SC, green) and the trabecular meshwork (TM, orange). The left inset shows an expanded view of the Schlemm’s canal’s microanatomy detailing the cell morphology of the inner and outer wall endocrine cells. The inner wall endocrine cells, shown in blue, line the canal surface facing the trabecular meshwork. Some of the inner wall cells contain giant vacuoles.") foaf:depiction obo:CL_4033098 "http://purl.obolibrary.org/obo/cl/images/Schlemms_canal_endo_cell_PMID26402712.png"^^xsd:anyURI)
SubClassOf(obo:CL_4033098 obo:CL_4033097)
SubClassOf(obo:CL_4033098 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0046930))

# Class: obo:CL_4033099 (outer wall Schlemm's canal endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1426078") Annotation(oboInOwl:hasDbXref "PMID:15454474") Annotation(oboInOwl:hasDbXref "PMID:26402712") obo:IAO_0000115 obo:CL_4033099 "A Schlemm's canal endothelial cell that lines the outer wall of the Schlemm's canal. This cell displays a smooth and flat morphology (Dautriche et al., 2015) and it is distinguished by the presence of Weibel-Palade bodies, specialized organelles that produce, store, and release P-Selectin (Hamanaka et al., 1992). This endothelial cell also exhibits stellate (star-shaped) actin arrangements distributed throughout much of the cell (Ethier et al., 2004).")
AnnotationAssertion(terms:contributor obo:CL_4033099 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033099 "2025-06-17T13:33:41Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4033099 "outer wall Schlemm's canal endothelial cell")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:26402712") Annotation(rdfs:comment "Schematic of the conventional outflow pathway, showing the Schlemm's canal (SC, green) and the trabecular meshwork (TM, orange). The left inset shows an expanded view of the Schlemm’s canal’s microanatomy detailing the cell morphology of the inner and outer wall endocrine cells. The outer wall endocrine cells, shown in green, line the side of Schlemm’s canal facing the collector channels and venous system.") foaf:depiction obo:CL_4033099 "http://purl.obolibrary.org/obo/cl/images/Schlemms_canal_endo_cell_PMID26402712.png"^^xsd:anyURI)
SubClassOf(obo:CL_4033099 obo:CL_4033097)
SubClassOf(obo:CL_4033099 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0033093))
SubClassOf(obo:CL_4033099 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001432))

# Class: obo:CL_4040000 (glial restricted tripotential precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10719353") obo:IAO_0000115 obo:CL_4040000 "A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes.")
AnnotationAssertion(terms:contributor obo:CL_4040000 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040000 "2023-04-03T14:54:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10719353") oboInOwl:hasBroadSynonym obo:CL_4040000 "glial restricted precursor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11921204") oboInOwl:hasExactSynonym obo:CL_4040000 "tripotential glial-restricted precursor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11756508") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4040000 "GRP cell")
AnnotationAssertion(rdfs:label obo:CL_4040000 "glial restricted tripotential precursor cell")
SubClassOf(obo:CL_4040000 obo:CL_0000123)
SubClassOf(obo:CL_4040000 obo:CL_0011115)

# Class: obo:CL_4040001 (chorionic girdle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27280409") Annotation(oboInOwl:hasDbXref "PMID:35328607") obo:IAO_0000115 obo:CL_4040001 "A horse-specific, highly invasive trophoblast cell that invades the endometrium where it forms endometrial cups.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4040001 obo:NCBITaxon_9789)
AnnotationAssertion(terms:contributor obo:CL_4040001 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040001 "2023-04-03T15:08:05Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35328607") oboInOwl:hasExactSynonym obo:CL_4040001 "equine chorionic girdle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27280409") rdfs:comment obo:CL_4040001 "Humans, mice and rats have a highly invasive (hemochorial) placentation. Horses have a non-invasive epitheliochorial placenta, except for the transient endometrial cup.")
AnnotationAssertion(rdfs:label obo:CL_4040001 "chorionic girdle cell")
SubClassOf(obo:CL_4040001 obo:CL_0000351)
SubClassOf(obo:CL_4040001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003124))

# Class: obo:CL_4040002 (enteroglial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16336493") Annotation(oboInOwl:hasDbXref "PMID:17483847") Annotation(oboInOwl:hasDbXref "PMID:25975510") obo:IAO_0000115 obo:CL_4040002 "Glial cell that provides support to the enteric nervous system. It is involved in enteric neurotransmission, in maintaining the integrity of the mucosal barrier of the gut and serves as a link between the nervous and immune systems of the gut. In enteric nerve strands, glial processes ensheath multiaxonal bundles which distinguishes enteric glia from all other peripheral glia. Ultrastructurally, the most conspicuous trait of an enteroglial cell is the presence of 10 nm filaments, which criss-cross the cell body, form axial bundles in the processes and appear to firmly anchor the cells to the ganglionic surfaces. Similar to astrocytes, their main constituent is glial fibrillary acidic protein (GFAP).")
AnnotationAssertion(terms:contributor obo:CL_4040002 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040002 "2023-04-03T15:15:40Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11169131") Annotation(oboInOwl:hasDbXref "PMID:25170211") oboInOwl:hasExactSynonym obo:CL_4040002 "enteric glial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11169131") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4040002 "enteric glia")
AnnotationAssertion(rdfs:label obo:CL_4040002 "enteroglial cell")
EquivalentClasses(obo:CL_4040002 ObjectIntersectionOf(obo:CL_0000125 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002005)))
SubClassOf(obo:CL_4040002 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007939))

# Class: obo:CL_4040003 (fetal pre-type II pulmonary alveolar epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:1316350") obo:IAO_0000115 obo:CL_4040003 "Precursor of type II pneumocyte. These cells do not have lamellar bodies, which are a marker of type II pneumocyte maturity.")
AnnotationAssertion(terms:contributor obo:CL_4040003 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040003 "2023-06-02T09:19:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9624168") oboInOwl:hasExactSynonym obo:CL_4040003 "fetal alveolar pre-type II epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-0819-0473") oboInOwl:hasExactSynonym obo:CL_4040003 "fetal pre-type 2 pneumocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12114192") oboInOwl:hasExactSynonym obo:CL_4040003 "fetal pre-type II alveolar epithelial cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4040003 "fetal pre-type II pneumocyte")
AnnotationAssertion(rdfs:comment obo:CL_4040003 "According to PMID:1316350 this cell type does not yet produce surfactant. According to PMID:9109447 and PMID:12114192 this cell type produces low levels of surfactant that can be increased by administration of very low-density lipoproteins. This cell type is of medical relevance, as a central feature of the fetal respiratory distress syndrome seems to be the presence in the lung of abundant pre-type II alveolar epithelial cells (PMID:1316350).")
AnnotationAssertion(rdfs:label obo:CL_4040003 "fetal pre-type II pulmonary alveolar epithelial cell")
SubClassOf(obo:CL_4040003 obo:CL_0000322)

# Class: obo:CL_4040004 (mesenchymal stem cell of orbital adipose tissue)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0002-0819-0473>) obo:IAO_0000115 obo:CL_4040004 "Any mesenchymal stem cell of adipose tissue that is part of an orbital region.")
AnnotationAssertion(terms:contributor obo:CL_4040004 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040004 "2023-09-18T10:43:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31377878") oboInOwl:hasExactSynonym obo:CL_4040004 "OAMSC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30210548") oboInOwl:hasExactSynonym obo:CL_4040004 "Orbital ASCs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31377878") oboInOwl:hasExactSynonym obo:CL_4040004 "orbital adipose-derived mesenchymal stem cell")
AnnotationAssertion(rdfs:label obo:CL_4040004 "mesenchymal stem cell of orbital adipose tissue")
EquivalentClasses(obo:CL_4040004 ObjectIntersectionOf(obo:CL_0002570 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004088)))

# Class: obo:CL_4040005 (mesenchymal stem cell of apical papilla)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30834270") Annotation(oboInOwl:hasDbXref "PMID:34026757") obo:IAO_0000115 obo:CL_4040005 "A mesenchymal stem cell that is part of the apical papilla tooth root.")
AnnotationAssertion(terms:contributor obo:CL_4040005 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040005 "2023-11-02T09:44:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30834270") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasBroadSynonym obo:CL_4040005 "stem cells from the apical papilla")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37887345") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4040005 "SCAP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30834270") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasRelatedSynonym obo:CL_4040005 "SCAPs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34026757") rdfs:comment obo:CL_4040005 "The mesenchymal stem cells of the apical papilla have high capacity for osteogenic, adipogenic, and chondrogenic differentiation.")
AnnotationAssertion(rdfs:label obo:CL_4040005 "mesenchymal stem cell of apical papilla")
SubClassOf(obo:CL_4040005 obo:CL_0000134)
SubClassOf(obo:CL_4040005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003677))

# Class: obo:CL_4040006 (dermal chromatophore)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28553007") obo:IAO_0000115 obo:CL_4040006 "A chromatophore that is part of the dermis.")
AnnotationAssertion(terms:contributor obo:CL_4040006 <https://orcid.org/0000-0002-0819-0473>)
AnnotationAssertion(terms:date obo:CL_4040006 "2024-03-07T09:37:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4040006 "dermal chromatophore")
SubClassOf(obo:CL_4040006 obo:CL_0000147)
SubClassOf(obo:CL_4040006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067))

# Class: obo:CL_4042001 (TAC3-positive striatal interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32999462") Annotation(oboInOwl:hasDbXref "PMID:34727523") obo:IAO_0000115 obo:CL_4042001 "A GABAergic interneuron that has its soma located in the striatum and that has an enriched expression of the genes TAC3 and LHX6.")
AnnotationAssertion(terms:contributor obo:CL_4042001 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042001 "2024-03-05T14:29:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") oboInOwl:hasExactSynonym obo:CL_4042001 "TAC3 interneuron")
AnnotationAssertion(rdfs:label obo:CL_4042001 "TAC3-positive striatal interneuron"@en)
SubClassOf(obo:CL_4042001 obo:CL_0011005)
SubClassOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016004))

# Class: obo:CL_4042002 (TAC3-positive medium spiny neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") obo:IAO_0000115 obo:CL_4042002 "A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron that co-expresses TAC3 and the DRD1 receptor.")
AnnotationAssertion(terms:contributor obo:CL_4042002 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042002 "2024-03-05T13:36:54Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042002 "D1Sh TAC3 archetype")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042002 "TAC3-positive D1Sh-MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042002 "TAC3-positive MSN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727523") rdfs:comment obo:CL_4042002 "A TAC3-positive medium spiny neuron has its soma in a cluster in the medial shell region of the nucleus accumbens. In Rhesus Macaque, this medium spiny neuron has an enriched expression of the genes MPPED1, HPCAL1, MEIS3.")
AnnotationAssertion(rdfs:label obo:CL_4042002 "TAC3-positive medium spiny neuron"@en)
SubClassOf(obo:CL_4042002 obo:CL_4030051)
SubClassOf(obo:CL_4042002 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016004))

# Class: obo:CL_4042003 (border associated macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:37626977") obo:IAO_0000115 obo:CL_4042003 "A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier.")
AnnotationAssertion(terms:contributor obo:CL_4042003 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042003 "2024-03-26T16:39:56Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36945367") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042003 "BAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042003 "CAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") oboInOwl:hasRelatedSynonym obo:CL_4042003 "CNS-associated macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29426702") Annotation(oboInOwl:hasDbXref "PMID:37232741") rdfs:comment obo:CL_4042003 "In humans, a border associate macrophage expresses CD45 and CD11B. This cell is also known to have the following molecular signature: CD206, CD38, LYVE1, CD163, CD169.")
AnnotationAssertion(rdfs:label obo:CL_4042003 "border associated macrophage"@en)
SubClassOf(obo:CL_4042003 obo:CL_0000878)

# Class: obo:CL_4042004 (choroid epiplexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_4042004 "A choroid plexus macrophage that is part of the apical surface of some choroid plexus epithelium. This macrophage has a star-like shaped body.")
AnnotationAssertion(terms:contributor obo:CL_4042004 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042004 "2024-03-26T19:14:58Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31433571") oboInOwl:hasExactSynonym obo:CL_4042004 "Kolmer’s cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042004 "cpepiMΦ")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042004 "epiplexus cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042004 "choroid epiplexus macrophage"@en)
SubClassOf(obo:CL_4042004 obo:CL_0000880)
SubClassOf(obo:CL_4042004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003911))

# Class: obo:CL_4042005 (stromal choroid plexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") obo:IAO_0000115 obo:CL_4042005 "A choroid plexus macrophage that is part of a choroid plexus stroma.")
AnnotationAssertion(terms:contributor obo:CL_4042005 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042005 "2024-03-26T19:21:51Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37626977") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042005 "cpstMΦ")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042005 "stromal cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042005 "stromal choroid plexus macrophage"@en)
SubClassOf(obo:CL_4042005 obo:CL_0000880)
SubClassOf(obo:CL_4042005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005206))

# Class: obo:CL_4042006 (dural macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") obo:IAO_0000115 obo:CL_4042006 "A border associated macrophage which is part of a dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4042006 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042006 "2024-03-26T19:27:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042006 "dmMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042006 "dural macrophage"@en)
SubClassOf(obo:CL_4042006 obo:CL_4042003)
SubClassOf(obo:CL_4042006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002092))

# Class: obo:CL_4042007 (protoplasmic astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19279265") Annotation(oboInOwl:hasDbXref "PMID:25904839") Annotation(oboInOwl:hasDbXref "PMID:34616062") Annotation(oboInOwl:hasDbXref "PMID:37139179") Annotation(oboInOwl:hasDbXref "PMID:37824655") obo:IAO_0000115 obo:CL_4042007 "An astrocyte with highly branched protrusions, found in neocortex layers 2-6. It is involved with the formation and elimination of synapses, glutamate clearance, modulation of synaptic functions and regulation of blood flow in response to synaptic activity.")
AnnotationAssertion(terms:contributor obo:CL_4042007 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042007 "2024-04-08T16:01:24Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19279265") Annotation(oboInOwl:hasDbXref "PMID:20012068") rdfs:comment obo:CL_4042007 "This astrocyte extends its branches to several hundred of dendrites to multiple neurons to envelope 100,000 or more synapses. In humans, a protoplasmic astrocyte has an average diameter of 142 µm, and its diameter ranges between 100 and 400 µm. In rodents the average diameter of a protoplasmic astrocites is 56 µm.")
AnnotationAssertion(rdfs:label obo:CL_4042007 "protoplasmic astrocyte"@en)
SubClassOf(obo:CL_4042007 obo:CL_0002605)
SubClassOf(obo:CL_4042007 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001950))

# Class: obo:CL_4042008 (fibrous astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19279265") Annotation(oboInOwl:hasDbXref "PMID:22144298") Annotation(oboInOwl:hasDbXref "PMID:28280934") Annotation(oboInOwl:hasDbXref "PMID:31435019") Annotation(oboInOwl:hasDbXref "PMID:34616062") Annotation(oboInOwl:hasDbXref "PMID:37824655") obo:IAO_0000115 obo:CL_4042008 "A cell type located in the first layer of the neocortex with radial protrusions extending transversely into the deeper cortex layers, herby facilitating communication across neurons, astrocytes, capillaries, meninges and cerebrospinal fluid through contact with neurons, pia mater and capillaries.")
AnnotationAssertion(terms:contributor obo:CL_4042008 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042008 "2024-04-08T16:29:28Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28280934") rdfs:comment obo:CL_4042008 "In humans, a fibrous astrocyte diameter is circa 182 µm. In rodents, a fibrous astrocyte diameter is circa 85 µm.")
AnnotationAssertion(rdfs:label obo:CL_4042008 "fibrous astrocyte"@en)
SubClassOf(obo:CL_4042008 obo:CL_0000127)
SubClassOf(obo:CL_4042008 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002316))

# Class: obo:CL_4042009 (interlaminar astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19279265") Annotation(oboInOwl:hasDbXref "PMID:30552685") Annotation(oboInOwl:hasDbXref "PMID:31435019") Annotation(oboInOwl:hasDbXref "PMID:32930323") Annotation(oboInOwl:hasDbXref "PMID:34616062") Annotation(oboInOwl:hasDbXref "PMID:37824655") obo:IAO_0000115 obo:CL_4042009 "An astrocyte type that presents radial protrusions across the layers of a cortex. The soma of this astrocyte is part of the first layer of a neocortex. This astrocyte extents its protrusions transversally to the deeper layers of a cortex and it creates contact with neurons, the pia matter and capillaries. This astrocyte is involved in facilitating the communication across neurons, astrocytes, capillaries, meninges and the cerebrospinal fluid.")
AnnotationAssertion(terms:contributor obo:CL_4042009 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042009 "2024-04-08T16:33:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30552685") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042009 "ILA")
AnnotationAssertion(rdfs:label obo:CL_4042009 "interlaminar astrocyte"@en)
SubClassOf(obo:CL_4042009 obo:CL_0002605)
SubClassOf(obo:CL_4042009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001950))

# Class: obo:CL_4042010 (pial interlaminar astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32930323") Annotation(oboInOwl:hasDbXref "PMID:37139179") obo:IAO_0000115 obo:CL_4042010 "An interlaminar astrocyte whose soma is part of the first layer of a neocortex and is in contact with a pia surface.")
AnnotationAssertion(terms:contributor obo:CL_4042010 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042010 "2024-04-08T16:37:57Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4042010 "pial interlaminar astrocyte"@en)
SubClassOf(obo:CL_4042010 obo:CL_4042009)

# Class: obo:CL_4042011 (subpial interlaminar astrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32930323") Annotation(oboInOwl:hasDbXref "PMID:37139179") obo:IAO_0000115 obo:CL_4042011 "An interlaminar astrocyte type whose soma is part of the upper first layer of the neocortex and its processes extend to a pia surface.")
AnnotationAssertion(terms:contributor obo:CL_4042011 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042011 "2024-04-08T16:39:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4042011 "subpial interlaminar astrocyte"@en)
SubClassOf(obo:CL_4042011 obo:CL_4042009)
SubClassOf(obo:CL_4042011 ObjectSomeValuesFrom(obo:RO_0002170 obo:UBERON_0002361))

# Class: obo:CL_4042012 (L2 marginal neuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4042012 "L2MN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29311847") Annotation(oboInOwl:hasDbXref "PMID:32108571") obo:IAO_0000115 obo:CL_4042012 "An L2 intratelencephalic projecting glutamatergic neuron with a soma on the L1-L2 border. This neuron type has small apical dendrites projecting to L1.")
AnnotationAssertion(terms:contributor obo:CL_4042012 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042012 "2024-04-23T09:31:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32108571") oboInOwl:hasExactSynonym obo:CL_4042012 "layer 2 marginal neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29311847") Annotation(oboInOwl:hasDbXref "PMID:32108571") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042012 "L2MN")
AnnotationAssertion(rdfs:label obo:CL_4042012 "L2 marginal neuron"@en)
SubClassOf(obo:CL_4042012 obo:CL_4030060)

# Class: obo:CL_4042013 (Lamp5 Lhx6 neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:36007006") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "PMID:37824669") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4042013 "A transcriptomically distinct GABAergic interneuron marked by Lamp5 and Lhx6 expression, derived from the Medial Ganglionic Eminence (MGE), and located in the pallium.")
AnnotationAssertion(terms:contributor obo:CL_4042013 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042013 "2024-04-23T09:37:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36007006") oboInOwl:hasExactSynonym obo:CL_4042013 "Ivy cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") oboInOwl:hasExactSynonym obo:CL_4042013 "Lamp5-Lhx6 type")
AnnotationAssertion(rdfs:label obo:CL_4042013 "Lamp5 Lhx6 neuron"@en)
SubClassOf(obo:CL_4042013 obo:CL_4023069)
SubClassOf(obo:CL_4042013 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000203))
SubClassOf(obo:CL_4042013 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004024))
SubClassOf(obo:CL_4042013 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4042013 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000032148))
SubClassOf(obo:CL_4042013 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000032533))

# Class: obo:CL_4042014 (spiny VIP neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35418660") obo:IAO_0000115 obo:CL_4042014 "A VIP GABAergic cortical interneuron with a soma located in L1-3 of some neocortex in Mmus. This neuron has a multipolar morphology with spiny dendrites concentrating on L1 of the cortex, and has a burst firing electrophysiological signature with highly dynamic dendritic spines.")
AnnotationAssertion(terms:contributor obo:CL_4042014 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042014 "2024-07-11T12:09:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35418660") oboInOwl:hasExactSynonym obo:CL_4042014 "superficial VIP-positive spiny neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35418660") oboInOwl:hasRelatedSynonym obo:CL_4042014 "multipolar VIP neuron")
AnnotationAssertion(rdfs:label obo:CL_4042014 "spiny VIP neuron"@en)
SubClassOf(obo:CL_4042014 obo:CL_4023016)
SubClassOf(obo:CL_4042014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001950))

# Class: obo:CL_4042015 (VIP-ChAT interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:31754098") Annotation(oboInOwl:hasDbXref "PMID:32027647") Annotation(oboInOwl:hasDbXref "PMID:33301603") obo:IAO_0000115 obo:CL_4042015 "A VIP GABAergic cortical interneuron expressing vasoactive intestinal polypeptide and choline acetyltransferase in the Mmus neocortex. This interneuron releases both γ-aminobutyric acid and acetylcholine.")
AnnotationAssertion(terms:contributor obo:CL_4042015 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042015 "2024-07-11T12:22:48Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33301603") oboInOwl:hasExactSynonym obo:CL_4042015 "VIP+/ChAT+ interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32027647") oboInOwl:hasExactSynonym obo:CL_4042015 "VIP/ChAT interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32027647") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042015 "VChI")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33301603") oboInOwl:hasRelatedSynonym obo:CL_4042015 "VIP+/ChAT+ cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:32027647") Annotation(oboInOwl:hasDbXref "PMID:33301603") rdfs:comment obo:CL_4042015 "Work in the mouse barrel cortex and somatosensory cortex shows that a VIP-ChAT interneuron is predominantely located in L2/3 and more rarely in the deeper layers of the cortex (Dudai et al., 2021; Dudai et al., 2020). This neuronal type could be transcriptomically distinct as transcriptomic studies have identified VIP neurons expressing ChAT in a whole brain mouse transcriptomic study (Tasic et al., 2018).")
AnnotationAssertion(rdfs:label obo:CL_4042015 "VIP-ChAT interneuron"@en)
SubClassOf(obo:CL_4042015 obo:CL_4023016)
SubClassOf(obo:CL_4042015 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014055))

# Class: obo:CL_4042016 (nasal serous secreting cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37291214") obo:IAO_0000115 obo:CL_4042016 "A serous secreting cell that is part of a submucosal gland in the nasal cavity respiratory epithelium.")
AnnotationAssertion(terms:contributor obo:CL_4042016 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042016 "2024-07-12T10:58:06Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4042016 "https://cellxgene.cziscience.com/e/9f222629-9e39-47d0-b83f-e08d610c7479.cxg/")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11005715") oboInOwl:hasRelatedSynonym obo:CL_4042016 "nasal mucous secretory cell")
AnnotationAssertion(rdfs:label obo:CL_4042016 "nasal serous secreting cell"@en)
SubClassOf(obo:CL_4042016 obo:CL_0000313)
SubClassOf(obo:CL_4042016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005385))
SubClassOf(obo:CL_4042016 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011148))

# Class: obo:CL_4042017 (alpha1-tanycyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16344112") Annotation(oboInOwl:hasDbXref "PMID:26578855") Annotation(oboInOwl:hasDbXref "wikipedia:Tanycyte") obo:IAO_0000115 obo:CL_4042017 "The dorsal-most tanycyte type of the third venticle.  These cells projects into the ventromedial or dorsomedial nucleus of the hypothalamus. This type of tanycyte extends its protrusions close to parenchymal neurons without contacting blood vessels. It expresses the glial marker S-100β.")
AnnotationAssertion(terms:contributor obo:CL_4042017 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042017 "2024-08-19T13:06:16Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasRelatedSynonym obo:CL_4042017 "DMH tanycyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasRelatedSynonym obo:CL_4042017 "VMH tanycyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26578855") rdfs:comment obo:CL_4042017 "In rodents, a1 tanycytes are known to express DARPP-32, GPR50, NA Vimentin, Connexin 43, GLT-1, GLUT1(+) (Goodman and Hajihosseini 2015; Prevot et al., 2018).")
AnnotationAssertion(rdfs:label obo:CL_4042017 "alpha1-tanycyte"@en)
AnnotationAssertion(Annotation(terms:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fendo.2019.00401>) foaf:depiction obo:CL_4042017 <http://purl.obolibrary.org/obo/cl/images/fendo-10-00401-g001.jpg>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fnins.2022.1129414>) Annotation(rdfs:comment "α1 tanycytes are the most dorsally located subtype, followed by α2 tanycytes, then β1 tanycytes, and finally β2 tanycytes which occupy the ventricular floor. 3V, third ventricle; Arc, arcuate nucleus; DMH, dorsomedial hypothalamic nucleus; VMH, ventromedial hypothalamic nucleus.") foaf:depiction obo:CL_4042017 <http://purl.obolibrary.org/obo/cl/images/fnins-16-1129414-g001.jpg>)
SubClassOf(obo:CL_4042017 obo:CL_0002085)
SubClassOf(obo:CL_4042017 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004642))
SubClassOf(obo:CL_4042017 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000014419))

# Class: obo:CL_4042018 (alpha2-tanycyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16344112") Annotation(oboInOwl:hasDbXref "PMID:26578855") Annotation(oboInOwl:hasDbXref "PMID:29351662") Annotation(oboInOwl:hasDbXref "wikipedia:Tanycyte") obo:IAO_0000115 obo:CL_4042018 "Tanycyte of the third ventricle, located immediately ventral to alpha-1 tanycytes. These cells project to the ventromedial and arcuate nuclei of the hypothalamus and express the glial marker S-100β.")
AnnotationAssertion(terms:contributor obo:CL_4042018 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042018 "2024-08-19T13:13:20Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasRelatedSynonym obo:CL_4042018 "dmARH tanycyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26578855") rdfs:comment obo:CL_4042018 "In rodents, this type of tanycyte is more developmentally advanced than alpha1 tanycytes, shows a high neurogenic competence and expresses the following markers DARPP-32, Vimentin, GPR50, Connexin-43, GLT-1, GLUT1(+) (Goodman and Hajihosseini 2015; Prevot et al., 2018)")
AnnotationAssertion(rdfs:label obo:CL_4042018 "alpha2-tanycyte"@en)
AnnotationAssertion(Annotation(terms:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fendo.2019.00401>) foaf:depiction obo:CL_4042018 <http://purl.obolibrary.org/obo/cl/images/fendo-10-00401-g001.jpg>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fnins.2022.1129414>) Annotation(rdfs:comment "α1 tanycytes are the most dorsally located subtype, followed by α2 tanycytes, then β1 tanycytes, and finally β2 tanycytes which occupy the ventricular floor. 3V, third ventricle; Arc, arcuate nucleus; DMH, dorsomedial hypothalamic nucleus; VMH, ventromedial hypothalamic nucleus.") foaf:depiction obo:CL_4042018 <http://purl.obolibrary.org/obo/cl/images/fnins-16-1129414-g001.jpg>)
SubClassOf(obo:CL_4042018 obo:CL_0002085)
SubClassOf(obo:CL_4042018 ObjectSomeValuesFrom(obo:RO_0002131 obo:UBERON_0001932))
SubClassOf(obo:CL_4042018 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000014419))

# Class: obo:CL_4042019 (beta1-tanycyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16344112") Annotation(oboInOwl:hasDbXref "PMID:26578855") Annotation(oboInOwl:hasDbXref "PMID:29351662") Annotation(oboInOwl:hasDbXref "Wikipedia:Tanycyte") obo:IAO_0000115 obo:CL_4042019 "A type of tanycyte located in ventral part of the lateral wall of the third ventricle and in the lateral infundibular recess of the brain. This tanycyte has an elongated morphology with multiple microvilli extending into the median eminence. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH).")
AnnotationAssertion(terms:contributor obo:CL_4042019 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042019 "2024-08-19T13:17:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasRelatedSynonym obo:CL_4042019 "vmARH tanycyte")
AnnotationAssertion(rdfs:label obo:CL_4042019 "beta1-tanycyte"@en)
AnnotationAssertion(Annotation(terms:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fendo.2019.00401>) foaf:depiction obo:CL_4042019 <http://purl.obolibrary.org/obo/cl/images/fendo-10-00401-g001.jpg>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fnins.2022.1129414>) Annotation(rdfs:comment "α1 tanycytes are the most dorsally located subtype, followed by α2 tanycytes, then β1 tanycytes, and finally β2 tanycytes which occupy the ventricular floor. 3V, third ventricle; Arc, arcuate nucleus; DMH, dorsomedial hypothalamic nucleus; VMH, ventromedial hypothalamic nucleus.") foaf:depiction obo:CL_4042019 <http://purl.obolibrary.org/obo/cl/images/fnins-16-1129414-g001.jpg>)
SubClassOf(obo:CL_4042019 obo:CL_0002085)
SubClassOf(obo:CL_4042019 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006250))
SubClassOf(obo:CL_4042019 ObjectSomeValuesFrom(obo:RO_0002131 obo:UBERON_0002197))
SubClassOf(obo:CL_4042019 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032274))
SubClassOf(obo:CL_4042019 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007479))
SubClassOf(obo:CL_4042019 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007489))

# Class: obo:CL_4042020 (beta2-tanycyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16344112") Annotation(oboInOwl:hasDbXref "PMID:26578855") Annotation(oboInOwl:hasDbXref "PMID:29351662") Annotation(oboInOwl:hasDbXref "wikipedia:Tanycyte") obo:IAO_0000115 obo:CL_4042020 "A type of tanycyte located in the floor of third ventricle and the infindibular recess. This tanycyte has an elongated morphology with multiple microvilli extending medially and ventrally to the median eminence, contacting the pial surface and blood vessels. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH).")
AnnotationAssertion(terms:contributor obo:CL_4042020 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042020 "2024-08-19T13:21:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29351662") oboInOwl:hasRelatedSynonym obo:CL_4042020 "ME tanycyte")
AnnotationAssertion(rdfs:label obo:CL_4042020 "beta2-tanycyte"@en)
AnnotationAssertion(Annotation(terms:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fendo.2019.00401>) foaf:depiction obo:CL_4042020 <http://purl.obolibrary.org/obo/cl/images/fendo-10-00401-g001.jpg>)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref <doi:10.3389/fnins.2022.1129414>) Annotation(rdfs:comment "α1 tanycytes are the most dorsally located subtype, followed by α2 tanycytes, then β1 tanycytes, and finally β2 tanycytes which occupy the ventricular floor. 3V, third ventricle; Arc, arcuate nucleus; DMH, dorsomedial hypothalamic nucleus; VMH, ventromedial hypothalamic nucleus.") foaf:depiction obo:CL_4042020 <http://purl.obolibrary.org/obo/cl/images/fnins-16-1129414-g001.jpg>)
SubClassOf(obo:CL_4042020 obo:CL_0002085)
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006250))
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:RO_0002131 obo:UBERON_0002197))
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007479))
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007489))

# Class: obo:CL_4042021 (neuronal-restricted precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10467245") obo:IAO_0000115 obo:CL_4042021 "A progenitor cell of the central nervous system that differentiates exclusively onto neurons. This progenitor cell is found in a hippocampus subventricular zone, developing cortex and spinal cord of the central nervous system.")
AnnotationAssertion(terms:contributor obo:CL_4042021 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042021 "2024-09-02T11:42:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:12429182") oboInOwl:hasRelatedSynonym obo:CL_4042021 "NRP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12429182") Annotation(oboInOwl:hasDbXref "PMID:9354325") rdfs:comment obo:CL_4042021 "In vitro cultures of embryonic mouse neural tubes show that neuronal-restricted precursors (NRPs) are derived from multipotent neuroepithelial cells to give rise to neurons. This progression suggests a linear relationship between multipotent progenitors and neuronal-restricted differentiation. (Mayer-Proschel et al., 1997). In the spinal cord of rats, neural-restricted precursor cells give rise cholinergic, GABAergic, glutametergic neurons (Cao and Howard et al., 2002).")
AnnotationAssertion(rdfs:label obo:CL_4042021 "neuronal-restricted precursor"@en)
SubClassOf(obo:CL_4042021 obo:CL_0000123)
SubClassOf(obo:CL_4042021 obo:CL_0011026)
SubClassOf(obo:CL_4042021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))

# Class: obo:CL_4042022 (astrocyte-restricted precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15531362") Annotation(oboInOwl:hasDbXref "PMID:33052610") obo:IAO_0000115 obo:CL_4042022 "A progenitor cell of the central nervous system that differentiates exclusively onto astrocytes. This progenitor cell expresses CD44 and S100 calcium-binding protein B.")
AnnotationAssertion(terms:contributor obo:CL_4042022 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042022 "2024-09-02T11:44:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:33052610") oboInOwl:hasRelatedSynonym obo:CL_4042022 "ARP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33052610") oboInOwl:hasRelatedSynonym obo:CL_4042022 "astrocyte precursor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33052610") rdfs:comment obo:CL_4042022 "In vitro, this progenitor cell can differentiate from glial-restricted precursor cells.")
AnnotationAssertion(rdfs:label obo:CL_4042022 "astrocyte-restricted precursor"@en)
SubClassOf(obo:CL_4042022 obo:CL_0000123)
SubClassOf(obo:CL_4042022 obo:CL_0011026)
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000127))
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001307))

# Class: obo:CL_4042023 (striatal pthlh-expressing interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30134177") Annotation(oboInOwl:hasDbXref "PMID:37292997") obo:IAO_0000115 obo:CL_4042023 "A GABAergic interneuron expressing PTHLH and PVALB that has its soma in a striatum. This GABAergic interneuron type presents a spatial expression gradient of PVALB in the mouse striatum.")
AnnotationAssertion(terms:contributor obo:CL_4042023 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042023 "2024-09-17T10:20:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292997") oboInOwl:hasRelatedSynonym obo:CL_4042023 "PTHLH/PVALB cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292997") oboInOwl:hasRelatedSynonym obo:CL_4042023 "PTHLH +/PVALB+ interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292997") rdfs:comment obo:CL_4042023 "According to spatial transcriptomic data in the human striatum, pthlh-expressing interneurons are one of the most abundant population of interneurons in the striatum (Leonardo D. Garma, et al., 2024).")
AnnotationAssertion(rdfs:label obo:CL_4042023 "striatal pthlh-expressing interneuron"@en)
SubClassOf(obo:CL_4042023 obo:CL_0011005)
SubClassOf(obo:CL_4042023 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_4042023 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013433))
SubClassOf(obo:CL_4042023 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013502))

# Class: obo:CL_4042024 (striatal PTHLH MOXD1 expressing interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30134177") obo:IAO_0000115 obo:CL_4042024 "A pthlh-expressing interneuron that expresses MOXD1 and has its soma in a striatum.")
AnnotationAssertion(terms:contributor obo:CL_4042024 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042024 "2024-09-17T10:26:57Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4042024 "striatal PTHLH MOXD1 expressing interneuron"@en)
SubClassOf(obo:CL_4042024 obo:CL_4042023)
SubClassOf(obo:CL_4042024 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000010529))

# Class: obo:CL_4042025 (substantia nigra dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32826893") Annotation(oboInOwl:hasDbXref "PMID:35308118") obo:IAO_0000115 obo:CL_4042025 "A midbrain dopaminergic neuron that has its soma located in a substantia nigra. This dopaminergic neuron type is highly metabolically active and it is involved in the regulation of movement, cognition, motivation and reward. Neurodegeneration of this dopaminergic neuronal type causes loss in fine motor control in Parkinson's Disease.")
AnnotationAssertion(terms:contributor obo:CL_4042025 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042025 "2024-09-16T13:09:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35308118") oboInOwl:hasNarrowSynonym obo:CL_4042025 "SNpc dopaminergic neuron")
AnnotationAssertion(rdfs:label obo:CL_4042025 "substantia nigra dopaminergic neuron"@en)
SubClassOf(obo:CL_4042025 obo:CL_0002614)
SubClassOf(obo:CL_4042025 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4042026 (GABAergic interneuron of the anterior substantia nigra pars reticulata)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36148148") obo:IAO_0000115 obo:CL_4042026 "A GABAergic interneuron that has its soma in the anterior section of the substantia nigra pars reticulata. This GABAergic interneuron is characterized by the expression of Six3 and Foxp1 and it develops from Nkx6-2 expressing neuronal progenitors in the ventrolateral midbrain-diencephalon region.")
AnnotationAssertion(terms:contributor obo:CL_4042026 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042026 "2024-09-23T13:56:01Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36148148") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042026 "aSNpr")
AnnotationAssertion(rdfs:label obo:CL_4042026 "GABAergic interneuron of the anterior substantia nigra pars reticulata"@en)
SubClassOf(obo:CL_4042026 obo:CL_0002614)
SubClassOf(obo:CL_4042026 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007643))
SubClassOf(obo:CL_4042026 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013047))
SubClassOf(obo:CL_4042026 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000014898))

# Class: obo:CL_4042027 (GABAergic interneuron of the posterior substantia nigra pars reticulata)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36148148") obo:IAO_0000115 obo:CL_4042027 "A GABAergic interneuron that has its soma in the posterior section of the substantia nigra pars reticulata. This GABAergic interneuron is characterised by the expression of the transcription factors Pax5, Ctip2 and Pou6f2 and it develops from the ventrolateral r1 neuroepithelium expresing NKX61.")
AnnotationAssertion(terms:contributor obo:CL_4042027 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042027 "2024-09-23T14:49:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36148148") oboInOwl:hasRelatedSynonym obo:CL_4042027 "pSNpr")
AnnotationAssertion(rdfs:label obo:CL_4042027 "GABAergic interneuron of the posterior substantia nigra pars reticulata"@en)
SubClassOf(obo:CL_4042027 obo:CL_0002614)
SubClassOf(obo:CL_4042027 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001903))

# Class: obo:CL_4042028 (immature neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31096632") Annotation(oboInOwl:hasDbXref "PMID:32116519") Annotation(oboInOwl:hasDbXref "PMID:37833544") obo:IAO_0000115 obo:CL_4042028 "A neuron in the central nervous system that is not committed to a differentiated fate, has not been newly derived from neurogenesis, and does not integrate into any circuit.")
AnnotationAssertion(terms:contributor obo:CL_4042028 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042028 "2024-10-10T09:14:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32116519") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042028 "IN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32116519") rdfs:comment obo:CL_4042028 "It is hypothesised that immature neurons can be utilised as a neurogenic reserve and that they can be involved in circuit plasticity.")
AnnotationAssertion(rdfs:label obo:CL_4042028 "immature neuron"@en)
SubClassOf(obo:CL_4042028 obo:CL_2000029)

# Class: obo:CL_4042029 (cortical immature neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37833544") obo:IAO_0000115 obo:CL_4042029 "An immature neuron of a cerebral cortex. This neuron develops prenatally and remains in an immature state throughout the lifespan of the organism.")
AnnotationAssertion(terms:contributor obo:CL_4042029 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042029 "2024-10-10T09:14:54Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37833544") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042029 "cIN")
AnnotationAssertion(rdfs:label obo:CL_4042029 "cortical immature neuron"@en)
SubClassOf(obo:CL_4042029 obo:CL_4042028)
SubClassOf(obo:CL_4042029 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000956))

# Class: obo:CL_4042030 (candelabrum cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35578131") obo:IAO_0000115 obo:CL_4042030 "A GABAergic interneuron located in the Purkinje layer of the cerebellar cortex. This GABAergic interneuron type has a distinct morphology, it presents a small cell soma near the Purkinje cell layer (PCL), dendrites that extend to the surface of the molecular layer, and beaded axons that make local synapses contacts within the molecular layer. A candelabrum cell is excited by mossy fibers and granule cells but inhibited by Purkinje cells, and it inhibits molecular layer interneurons, which leads to the disinhibition of Purkinje cells.")
AnnotationAssertion(terms:contributor obo:CL_4042030 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042030 "2024-10-15T11:06:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35578131") oboInOwl:hasExactSynonym obo:CL_4042030 "candelabrum interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35578131") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042030 "CC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35578131") rdfs:comment obo:CL_4042030 "Candelabrum cells are the most abundant interneurons in the Purkinje cell layer and are present in all cerebellar lobules.")
AnnotationAssertion(rdfs:label obo:CL_4042030 "candelabrum cell"@en)
AnnotationAssertion(Annotation(dc:license <https://creativecommons.org/licenses/by-nc-nd/4.0/>) Annotation(oboInOwl:hasDbXref "doi:10.3389/fnins.2020.00293") foaf:depiction obo:CL_4042030 <http://purl.obolibrary.org/obo/cl/images/Candelabrum_cell.jpg>)
SubClassOf(obo:CL_4042030 obo:CL_0000099)
SubClassOf(obo:CL_4042030 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002979))
SubClassOf(obo:CL_4042030 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_4042031 (immune oligodendroglia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30747918") Annotation(oboInOwl:hasDbXref "PMID:35301426") Annotation(oboInOwl:hasDbXref "PMID:35615276") Annotation(oboInOwl:hasDbXref "PMID:35662200") obo:IAO_0000115 obo:CL_4042031 "An oligodendrocyte of the central nervous system that exhibits immune properties such as self-presentation and non-self antigen presentation to T cells, phagocytosis of debris, and cytokine and chemokine production. Immune oligodendroglia is immunoreactive during inflammation, neurodegenerative disorders, chronic stress and major depressive disorder.")
AnnotationAssertion(terms:contributor obo:CL_4042031 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042031 "2024-10-11T12:51:17Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35615276") oboInOwl:hasExactSynonym obo:CL_4042031 "immune oligodendrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35301426") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042031 "Im-OL")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35615276") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042031 "ImOL")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30747918") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042031 "ImOLG")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30747918") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042031 "imOLG")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35301426") Annotation(oboInOwl:hasDbXref "PMID:35615276") Annotation(oboInOwl:hasDbXref "PMID:37057892") rdfs:comment obo:CL_4042031 "During inflammation, immuno oligodendroglia express MHC II to interact with immune cells in mouse models (Harrington et al., 2023; Madeira et al., 2022). In a mouse model of major depressive disorder and chronic stress, immuno oligodendroglia were associated with prefrontal cortex hypomyelination (Kokkosis et al., 2022).")
AnnotationAssertion(rdfs:label obo:CL_4042031 "immune oligodendroglia"@en)
SubClassOf(obo:CL_4042031 obo:CL_0000128)
SubClassOf(obo:CL_4042031 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002453))
SubClassOf(obo:CL_4042031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504))

# Class: obo:CL_4042032 (PAX6 GABAergic interneuron)

AnnotationAssertion(obo:IAO_0000028 obo:CL_4042032 "Pax6 interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4042032 "A transcriptomically distinct GABAergic neuron, located in the cerebral cortex and derived from the CGE, that expresses the transcript PAX6.")
AnnotationAssertion(terms:contributor obo:CL_4042032 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042032 "2024-10-11T13:25:51Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4042032 "PAX6 GABAergic interneuron"@en)
SubClassOf(obo:CL_4042032 obo:CL_0000099)
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000956))
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026))
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000012318))

# Class: obo:CL_4042033 (pro-opiomelanocortin neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25870542") Annotation(oboInOwl:hasDbXref "PMID:28192062") obo:IAO_0000115 obo:CL_4042033 "A neuron of the central nervous system that expresses POMC and synthesizes the POMC precursor polypeptide. This neuron type is located in the arcuate nucleus of the hypothalamus and in the nucleus tractus solitarius of the brainstem. The pro-opiomelanocortin neuron is part of the central melanocortin system and it is involved in regulating energy homeostasis, metabolism, and appetite. This neuronal type responds to hormonal signals such as levels of leptin and insulin, and its activation results in the release of α-melanocyte-stimulating hormone (α-MSH), which acts on melanocortin receptors to suppress food intake and increase energy expenditure.")
AnnotationAssertion(terms:contributor obo:CL_4042033 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042033 "2024-10-15T10:17:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34002087") oboInOwl:hasRelatedSynonym obo:CL_4042033 "POMC neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34002087") oboInOwl:hasRelatedSynonym obo:CL_4042033 "POMC-expressing neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28192062") Annotation(oboInOwl:hasDbXref "PMID:33633406") rdfs:comment obo:CL_4042033 "Pro-opiomelanocortin neurons have a diverse projection pattern. The neurons in the rostral arcuate nucleus project to autonomic areas, caudal arcuate POMC neurons project mainly to hypothalamic areas (Toda et al., 2017). Dysregulation of pro-opiomelanocortin neurons is associated with obesity and metabolic disorders (Quarta et al., 2020).")
AnnotationAssertion(rdfs:label obo:CL_4042033 "pro-opiomelanocortin neuron"@en)
SubClassOf(obo:CL_4042033 obo:CL_0000165)
SubClassOf(obo:CL_4042033 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013015))

# Class: obo:CL_4042034 (CGRP-expressing neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") obo:IAO_0000115 obo:CL_4042034 "An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn.")
AnnotationAssertion(terms:contributor obo:CL_4042034 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042034 "2024-10-30T15:35:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasExactSynonym obo:CL_4042034 "Calcitonin gene-related peptide neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042034 "CGRP-expressing interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042034 "CGRP-positive neuron")
AnnotationAssertion(rdfs:label obo:CL_4042034 "CGRP-expressing neuron"@en)
SubClassOf(obo:CL_4042034 obo:CL_0000526)
SubClassOf(obo:CL_4042034 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4042035 (molecular layer interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30742002") Annotation(oboInOwl:hasDbXref "PMID:33075461") Annotation(oboInOwl:hasDbXref "PMID:34616064") Annotation(oboInOwl:hasDbXref "PMID:38692278") obo:IAO_0000115 obo:CL_4042035 "A type of cerebellar inhibitory GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell type inhibits Purkinje cells and other molecular layer interneurons. This interneuron plays a crucial role in regulating cerebellar output through feedforward inhibition and is characterized by its fast-spiking properties.")
AnnotationAssertion(terms:contributor obo:CL_4042035 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042035 "2024-10-31T15:55:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33075461") Annotation(oboInOwl:hasRelatedSynonym obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042035 "MLI")
AnnotationAssertion(rdfs:label obo:CL_4042035 "molecular layer interneuron"@en)
EquivalentClasses(obo:CL_4042035 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002974) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534)))

# Class: obo:CL_4042036 (melanin-concentrating hormone neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30284033") Annotation(oboInOwl:hasDbXref "PMID:38020069") Annotation(oboInOwl:hasDbXref "PMID:39035036") obo:IAO_0000115 obo:CL_4042036 "A neuron of the central nervous system with its soma primarily located in the lateral hypothalamic area and surrounding regions, including the zona incerta. This neuron type expresses melanin-concentrating hormone and is involved in regulating various physiological processes, including sleep, feeding behavior, and energy homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4042036 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042036 "2024-10-31T16:03:26Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30284033") oboInOwl:hasRelatedSynonym obo:CL_4042036 "MCH neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38020069") rdfs:comment obo:CL_4042036 "Nearly all melanin-concentrating hormone neurons express the glutamate transporter VGlut2, however a small subset of them expresses the machinery for GABA release and neurotransmission.")
AnnotationAssertion(rdfs:label obo:CL_4042036 "melanin-concentrating hormone neuron"@en)
SubClassOf(obo:CL_4042036 obo:CL_2000029)

# Class: obo:CL_4042037 (sst GABAergic neuron of the striatum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30131490") Annotation(oboInOwl:hasDbXref "PMID:30467465") Annotation(oboInOwl:hasDbXref "PMID:33742131") obo:IAO_0000115 obo:CL_4042037 "A interneuron of the striatum expressing gamma-aminobutyric acid and somatostatin. This interneuron has a fusiform soma with a diameter between 9 - 25 µm, it has a long axon up to the length of 1mm. This neuron type displays a low threshold Ca2+ spike (LTS), a high input resistance, and the expression of long-lasting plateau potentials following depolarization from rest.")
AnnotationAssertion(terms:contributor obo:CL_4042037 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042037 "2024-11-27T18:33:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30131490") oboInOwl:hasBroadSynonym obo:CL_4042037 "SOM cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33742131") oboInOwl:hasRelatedSynonym obo:CL_4042037 "striatal SST+ IN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30467465") Annotation(oboInOwl:hasDbXref "PMID:33742131") rdfs:comment obo:CL_4042037 "Some striatal SST GABAergic neurons can co-release glutamate and generate excitation-inhibition responses in postsynaptic neurons. This interneuron type has the least dense dendritic branches in the striatum. In the dorsomedial striatum these neurons regulate the activity of striatal projection neurons.")
AnnotationAssertion(rdfs:label obo:CL_4042037 "sst GABAergic neuron of the striatum"@en)
SubClassOf(obo:CL_4042037 obo:CL_0000540)
SubClassOf(obo:CL_4042037 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002435))
SubClassOf(obo:CL_4042037 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4042037 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000015665))

# Class: obo:CL_4042038 (rostral primary motorneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35431796") Annotation(oboInOwl:hasDbXref "PMID:3746410") obo:IAO_0000115 obo:CL_4042038 "A type of primary motor neuron situated in the rostral region of the spinal cord. RoP neurons extend their axons to innervate the ventral trunk musculature.")
AnnotationAssertion(terms:contributor obo:CL_4042038 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042038 "2024-11-13T13:42:01Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3746410") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042038 "RoP")
AnnotationAssertion(rdfs:label obo:CL_4042038 "rostral primary motorneuron"@en)
SubClassOf(obo:CL_4042038 obo:CL_0000533)

# Class: obo:CL_4042039 (caudal ganglionic eminence derived neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12593982") Annotation(oboInOwl:hasDbXref "PMID:12637172") Annotation(oboInOwl:hasDbXref "PMID:20130169") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK98190/") obo:IAO_0000115 obo:CL_4042039 "A neuron of the central nervous system that develops from a caudal ganglionic eminence.")
AnnotationAssertion(terms:contributor obo:CL_4042039 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042039 "2024-11-14T11:27:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:12593982") Annotation(oboInOwl:hasDbXref "PMID:12637172") Annotation(oboInOwl:hasDbXref "PMID:20130169") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK98190/") rdfs:comment obo:CL_4042039 "Neurons derived from the caudal ganglionic eminence consist mostly of neurons populating the cortical layers of the brain and some subcortical areas such as the globus pallidus, the striatus and the hippocampus. Amongst neurons derived from the caudal ganglionic eminence there are cortical GABAergic neurons such as Pax6, Lamp5, VIP, sncg, GABAergic; in the hippocampus, mossy fibers, pyramidal neurons, granule neurons and interneurons; in the striatum and globus pallidus, medium spiny projection neurons.")
AnnotationAssertion(rdfs:label obo:CL_4042039 "caudal ganglionic eminence derived neuron"@en)
SubClassOf(obo:CL_4042039 obo:CL_2000029)
SubClassOf(obo:CL_4042039 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026))

# Class: obo:CL_4042040 (glutamatergic neuron of the basal ganglia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.jocn.2021.05.056") Annotation(oboInOwl:hasDbXref "PMID:11307040") Annotation(oboInOwl:hasDbXref "PMID:16276355") obo:IAO_0000115 obo:CL_4042040 "A glutametergic neuron with its soma located in a basal ganglia. This neuron type is involved in motor control, decision making and learning.")
AnnotationAssertion(terms:contributor obo:CL_4042040 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042040 "2024-11-18T13:37:58Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22498715") Annotation(oboInOwl:hasDbXref "PMID:30498197") Annotation(oboInOwl:hasDbXref "PMID:33785138") rdfs:comment obo:CL_4042040 "The glutametergic neurons in the basal ganglia are part of a series of different circuits such as the corticolstriatal circuit, which is involved in regulating voluntary movements. The subthalamic nucleus circuit, which is involved in modulating the output of the basal ganglia, particularly in controlling movement initiation and inhibition. The thalamocortical loop, which is involved in refining motor movements and integrating sensory information with motor commanding.")
AnnotationAssertion(rdfs:label obo:CL_4042040 "glutamatergic neuron of the basal ganglia"@en)
SubClassOf(obo:CL_4042040 obo:CL_0000540)
SubClassOf(obo:CL_4042040 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002420))
SubClassOf(obo:CL_4042040 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535))

# Class: obo:CL_4042041 (middle primary motoneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35431796") Annotation(oboInOwl:hasDbXref "PMID:3746410") obo:IAO_0000115 obo:CL_4042041 "A type of primary motor neuron located in the middle region of the spinal cord. This primary motor neuron type is characterized by their distinct axonal pathways that innervate the middle trunk muscles.")
AnnotationAssertion(terms:contributor obo:CL_4042041 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042041 "2024-11-13T13:39:28Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4042041 "ZFA:0005179")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3746410") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042041 "MiP")
AnnotationAssertion(rdfs:label obo:CL_4042041 "middle primary motoneuron"@en)
SubClassOf(obo:CL_4042041 obo:CL_0000533)

# Class: obo:CL_4047006 (fetal artery endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047006 "An endothelial cell that lines an artery in the fetal circulatory system.")
AnnotationAssertion(terms:contributor obo:CL_4047006 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047006 "2024-08-16T13:52:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") oboInOwl:hasExactSynonym obo:CL_4047006 "endothelial cell of fetal artery")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") oboInOwl:hasExactSynonym obo:CL_4047006 "fetal arterial EC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") oboInOwl:hasExactSynonym obo:CL_4047006 "fetal artery EC")
AnnotationAssertion(rdfs:label obo:CL_4047006 "fetal artery endothelial cell")
SubClassOf(obo:CL_4047006 obo:CL_1000413)

# Class: obo:CL_4047007 (immature pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21839917") Annotation(oboInOwl:hasDbXref "PMID:28564607") Annotation(oboInOwl:hasDbXref "PMID:32466671") Annotation(oboInOwl:hasDbXref "PMID:34497389") Annotation(oboInOwl:hasDbXref "PMID:36685855") obo:IAO_0000115 obo:CL_4047007 "A pericyte that is in an early stage of development, found in newly forming or remodeling blood vessels. An immature pericyte is characterized by it's mesenchymal stem cell-like properties and high proliferative capacity, which allows it to differentiate into various types of pericytes and contribute to the structural and functional maturation of the vasculature. Immature pericytes are stellate in new vessels and elongated with less protrusions in remodeling vessels.")
AnnotationAssertion(terms:contributor obo:CL_4047007 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047007 "2024-08-19T11:32:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28564607") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047007 "imPCs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28564607") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047007 "immature PCs")
AnnotationAssertion(rdfs:label obo:CL_4047007 "immature pericyte")
SubClassOf(obo:CL_4047007 obo:CL_0000669)

# Class: obo:CL_4047011 (fetal vein endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2021.04.07.438755") obo:IAO_0000115 obo:CL_4047011 "An endothelial cell that lines the veins in the fetal circulatory system.")
AnnotationAssertion(terms:contributor obo:CL_4047011 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047011 "2024-09-05T15:45:32Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2021.04.07.438755") oboInOwl:hasExactSynonym obo:CL_4047011 "fetal venous endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2021.04.07.438755") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047011 "fetal vein EC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2021.04.07.438755") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047011 "fetal venous EC")
AnnotationAssertion(rdfs:label obo:CL_4047011 "fetal vein endothelial cell"@en)
SubClassOf(obo:CL_4047011 obo:CL_0002543)

# Class: obo:CL_4047012 (angiogenic pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24853910") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047012 "A specialized pericyte that actively participates in the formation of new blood vessels during angiogenesis by undergoing phenotypic changes, increasing proliferation, and interacting closely with endothelial cells.")
AnnotationAssertion(terms:contributor obo:CL_4047012 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047012 "2024-09-06T08:41:39Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047012 "angiogenic pericyte"@en)
SubClassOf(obo:CL_4047012 obo:CL_0000669)

# Class: obo:CL_4047017 (transit amplifying cell of gut)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") Annotation(oboInOwl:hasDbXref "PMID:33195268") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047017 "A transit amplifying cell of the gut epithelium, located in the wall of the intestinal crypt, just above intestinal stem cells from which they derive. These are rapidly dividing cells, capable of multiple rounds of division before differentiating into the various cell types of the gut epithelium (enterocyte, goblet, eneterodendocrine, paneth cells).")
AnnotationAssertion(terms:contributor obo:CL_4047017 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047017 "2024-09-24T10:48:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24813615") oboInOwl:hasBroadSynonym obo:CL_4047017 "transit-amplifying cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") oboInOwl:hasRelatedSynonym obo:CL_4047017 "TA cell")
AnnotationAssertion(rdfs:label obo:CL_4047017 "transit amplifying cell of gut"@en)
EquivalentClasses(obo:CL_4047017 ObjectIntersectionOf(obo:CL_0009010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013740)))
SubClassOf(obo:CL_4047017 obo:CL_0000066)
SubClassOf(obo:CL_4047017 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_0002250))

# Class: obo:CL_4047018 (early colonocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28049136") Annotation(oboInOwl:hasDbXref "PMID:36060223") obo:IAO_0000115 obo:CL_4047018 "An enterocyte that is part of the colon, in the early stages of differentiation, located in the intestinal crypt-villus axis.")
AnnotationAssertion(terms:contributor obo:CL_4047018 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047018 "2024-09-24T11:50:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2021.01.13.426602") oboInOwl:hasExactSynonym obo:CL_4047018 "early enterocyte of colon")
AnnotationAssertion(rdfs:label obo:CL_4047018 "early colonocyte"@en)
EquivalentClasses(obo:CL_4047018 ObjectIntersectionOf(obo:CL_4047019 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397)))

# Class: obo:CL_4047019 (early enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20683682") Annotation(oboInOwl:hasDbXref "PMID:35235783") obo:IAO_0000115 obo:CL_4047019 "An enterocyte in the early stages of development, located above the transit-amplifying cell zone in the intestinal crypt-villus axis.")
AnnotationAssertion(terms:contributor obo:CL_4047019 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047019 "2024-09-24T12:11:09Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047019 "early enterocyte"@en)
EquivalentClasses(obo:CL_4047019 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013740)))

# Class: obo:CL_4047023 (intestinal lamina propria fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21252048") Annotation(oboInOwl:hasDbXref "PMID:36032088") obo:IAO_0000115 obo:CL_4047023 "A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin.")
AnnotationAssertion(terms:contributor obo:CL_4047023 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047023 "2024-09-24T15:45:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30270042") oboInOwl:hasRelatedSynonym obo:CL_4047023 "S1 fibroblast")
AnnotationAssertion(rdfs:label obo:CL_4047023 "intestinal lamina propria fibroblast"@en)
EquivalentClasses(obo:CL_4047023 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004780) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278)))

# Class: obo:CL_4047025 (type G cell of stomach)

AnnotationAssertion(terms:contributor obo:CL_4047025 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047025 "2024-10-24T10:43:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047025 "type G cell of stomach"@en)
EquivalentClasses(obo:CL_4047025 ObjectIntersectionOf(obo:CL_0000508 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))

# Class: obo:CL_4047029 (post-arteriole capillary cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17893694") Annotation(oboInOwl:hasDbXref "PMID:35406678") obo:IAO_0000115 obo:CL_4047029 "An endothelial cell forming the walls of capillaries immediately downstream from arterioles, facilitating the exchange of substances between blood and interstitial fluid. This cell is characterized by a small diameter and may be continuous, fenestrated, or sinusoidal, depending on their location and function. This cell plays a crucial role in tissue oxygenation, nutrient delivery, and maintaining homeostasis within the microvascular network.")
AnnotationAssertion(terms:contributor obo:CL_4047029 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047029 "2024-11-07T12:50:06Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047029 "post-arteriole capillary cell"@en)
SubClassOf(obo:CL_4047029 obo:CL_0002144)

# Class: obo:CL_4047030 (pre-venule capillary cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41467-022-33324-7") Annotation(oboInOwl:hasDbXref "PMID:23620236") obo:IAO_0000115 obo:CL_4047030 "A specialized endothelial cell located in the transition zone between capillaries and small venules in the microvascular system. It exhibits characteristics of both capillary and venous cells, expressing markers from both types. This cell plays a role in regulating blood flow and substance exchange between blood and tissues.")
AnnotationAssertion(terms:contributor obo:CL_4047030 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047030 "2024-11-07T13:22:16Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41467-022-33324-7") oboInOwl:hasExactSynonym obo:CL_4047030 "Cap-Venous endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4047030 "pre-venule capillary cell"@en)
SubClassOf(obo:CL_4047030 obo:CL_0002144)

# Class: obo:CL_4047032 (secretory pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2019.00282") obo:IAO_0000115 obo:CL_4047032 "A specialized pericyte located within the basement membrane of a blood capillary. This cell is characterized by its ability to produce and release a variety of bioactive molecules, collectively known as the pericyte secretome, including cytokines and regulators of angiogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4047032 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047032 "2024-11-07T15:36:16Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047032 "secretory pericyte"@en)
SubClassOf(obo:CL_4047032 obo:CL_0000669)
SubClassOf(obo:CL_4047032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816))
SubClassOf(obo:CL_4047032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940))
SubClassOf(obo:CL_4047032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045765))

# Class: obo:CL_4047034 (smooth muscle cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21443757") Annotation(oboInOwl:hasDbXref "PMID:33630273") obo:IAO_0000115 obo:CL_4047034 "A smooth muscle cell that is part of the muscularis externa of the stomach wall. It is characterized by its fusiform shape, involuntary control, and ability to generate slow, sustained contractions. This cell is organized in distinct layers and is essential for gastric motility and digestion.")
AnnotationAssertion(terms:contributor obo:CL_4047034 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047034 "2024-12-05T11:10:18Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047034 "smooth muscle cell of stomach"@en)
EquivalentClasses(obo:CL_4047034 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008856)))

# Class: obo:CL_4047035 (stomach smooth muscle outer longitudinal layer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21443757") Annotation(oboInOwl:hasDbXref "PMID:33630273") obo:IAO_0000115 obo:CL_4047035 "A specialized smooth muscle cell located in the outermost layer of the muscularis externa of the stomach wall. This cell is arranged longitudinally along the stomach's axis and is responsible for the contractions that facilitate food movement toward the pylorus.")
AnnotationAssertion(terms:contributor obo:CL_4047035 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047035 "2024-12-05T16:13:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047035 "stomach smooth muscle outer longitudinal layer cell"@en)
SubClassOf(obo:CL_4047035 obo:CL_4047034)

# Class: obo:CL_4047036 (stomach smooth muscle circular layer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11146428") Annotation(oboInOwl:hasDbXref "PMID:32424507") obo:IAO_0000115 obo:CL_4047036 "A smooth muscle cell located in the middle layer of the muscularis externa of the stomach wall. This cell is arranged concentrically with the stomach's longitudinal axis, forming a continuous sheet of contractile tissue. It is fusiform in shape, containing actin and myosin filaments that enable contraction without striations. This cell contributes to the mechanical digestion and movement of food within the stomach through coordinated contractions, and plays a role in forming the pyloric sphincter in the pyloric region.")
AnnotationAssertion(terms:contributor obo:CL_4047036 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047036 "2024-12-09T10:40:58Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047036 "stomach smooth muscle circular layer cell"@en)
EquivalentClasses(obo:CL_4047036 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008857)))

# Class: obo:CL_4047037 (stomach smooth muscle inner oblique layer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29493959") obo:IAO_0000115 obo:CL_4047037 "A smooth muscle cell found in the innermost layer of the muscularis externa of the stomach wall. This cell forms a unique layer of smooth muscle fibers oriented obliquely to the stomach's longitudinal axis. It is responsible for aiding in the mixing and churning of gastric contents, contributing to mechanical digestion within the stomach.")
AnnotationAssertion(terms:contributor obo:CL_4047037 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047037 "2024-12-09T10:53:19Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4047037 "stomach smooth muscle oblique layer cell")
AnnotationAssertion(rdfs:label obo:CL_4047037 "stomach smooth muscle inner oblique layer cell"@en)
EquivalentClasses(obo:CL_4047037 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008862)))

# Class: obo:CL_4047038 (dogiel type I neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41575-020-0271-2") Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41575-021-00561-y") Annotation(oboInOwl:hasDbXref "PMID:32152479") Annotation(oboInOwl:hasDbXref "PMID:34170401") obo:IAO_0000115 obo:CL_4047038 "A multipolar neuron in the myenteric plexus of the gastrointestinal tract, characterized by a small to medium-sized cell body and multiple short dendrites.  This neuron exhibits fast excitatory postsynaptic potentials and can be classified into stubby, spiny and hairy subtypes based on dendritic morphology. (Brehmer, 2021)")
AnnotationAssertion(terms:contributor obo:CL_4047038 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047038 "2024-12-16T13:42:04Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047038 "dogiel type I neuron")
SubClassOf(obo:CL_4047038 obo:CL_0000104)
SubClassOf(obo:CL_4047038 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002439))

# Class: obo:CL_4047040 (smooth muscle circular layer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18221249") Annotation(oboInOwl:hasDbXref "PMID:27445346") obo:IAO_0000115 obo:CL_4047040 "A smooth muscle cell that is found in the inner muscular layer of hollow organs. It is characterized by its spiral/helical arrangement around organ lumens. This cell is crucial for peristaltic movements in organs.")
AnnotationAssertion(terms:contributor obo:CL_4047040 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047040 "2025-01-06T15:40:21Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047040 "smooth muscle circular layer cell")
SubClassOf(obo:CL_4047040 obo:CL_0000192)
SubClassOf(obo:CL_4047040 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012368))

# Class: obo:CL_4047042 (type 1 myenteric plexus glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19906678") Annotation(oboInOwl:hasDbXref "PMID:21865647") Annotation(oboInOwl:hasDbXref "PMID:26964064") Annotation(oboInOwl:hasDbXref "PMID:28066889") Annotation(oboInOwl:hasDbXref "PMID:33731961") obo:IAO_0000115 obo:CL_4047042 "An enteric glial cell located within the myenteric ganglia of the gastrointestinal tract. This cell has a small somata and has very short, irregularly branched processes that surround neuron cell bodies, giving it a protoplasmic-like appearance. It plays crucial roles in modulating myenteric neuron activity, regulating oxidative stress, and influencing neuroinflammation and neurogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4047042 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047042 "2025-02-10T16:49:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047042 "type 1 MP")
AnnotationAssertion(rdfs:label obo:CL_4047042 "type 1 myenteric plexus glia")
SubClassOf(obo:CL_4047042 obo:CL_4040002)
SubClassOf(obo:CL_4047042 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002439))

# Class: obo:CL_4047043 (type 1 submucosal plexus glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2023.1170309") Annotation(oboInOwl:hasDbXref "PMID:28487635") Annotation(oboInOwl:hasDbXref "PMID:33731961") obo:IAO_0000115 obo:CL_4047043 "An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell is located in the submucosa, a layer of connective tissue beneath the intestinal mucosa. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption.")
AnnotationAssertion(terms:contributor obo:CL_4047043 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047043 "2025-02-10T17:02:28Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047043 "type I SMP")
AnnotationAssertion(rdfs:label obo:CL_4047043 "type 1 submucosal plexus glia")
SubClassOf(obo:CL_4047043 obo:CL_4040002)
SubClassOf(obo:CL_4047043 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009566))

# Class: obo:CL_4047044 (type 2 interganglionic glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1002/glia.22876") Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasDbXref "PMID:35111752") obo:IAO_0000115 obo:CL_4047044 "An enteric glial cell that has an elongated, fibrous morphology with long processes that run parallel to nerve fibers connecting enteric myenteric ganglia. This cell is located in the interganglionic fiber tracts of the enteric nervous system.")
AnnotationAssertion(terms:contributor obo:CL_4047044 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047044 "2025-02-11T12:28:37Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35111752") oboInOwl:hasExactSynonym obo:CL_4047044 "type II enteric glia")
AnnotationAssertion(rdfs:label obo:CL_4047044 "type 2 interganglionic glia")
SubClassOf(obo:CL_4047044 obo:CL_4040002)
SubClassOf(obo:CL_4047044 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000429))

# Class: obo:CL_4047045 (type 3 mucosal glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25161129") Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasDbXref "PMID:37153631") Annotation(oboInOwl:hasDbXref "PMID:38957473") obo:IAO_0000115 obo:CL_4047045 "An enteric glial cell located in the lamina propria of the intestinal mucosa. This cell plays important roles in maintaining gut barrier function, regulating intestinal homeostasis, and mediating interactions between the enteric nervous system and the immune system.")
AnnotationAssertion(terms:contributor obo:CL_4047045 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047045 "2025-02-11T12:39:11Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047045 "type 3 mucosal glia")
SubClassOf(obo:CL_4047045 obo:CL_4040002)
SubClassOf(obo:CL_4047045 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000030))

# Class: obo:CL_4047047 (type I enteric glial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.celrep.2023.112194") Annotation(oboInOwl:hasDbXref "PMID:29927320") Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasDbXref "PMID:35111752") obo:IAO_0000115 obo:CL_4047047 "An enteric glial cell located within the ganglia of the enteric nervous system. This cell is characterized by it’s small somata and short, irregularly branched processes that surround neuronal cell bodies in the myenteric and submucosal ganglia. This cell plays important roles in modulating neuronal activity and neurogenesis in the gastrointestinal tract.")
AnnotationAssertion(terms:contributor obo:CL_4047047 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047047 "2025-02-11T13:35:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33731961") oboInOwl:hasExactSynonym obo:CL_4047047 "intraganglionic glia")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4047047 "type 1 enteric glia")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35111752") oboInOwl:hasExactSynonym obo:CL_4047047 "type I enteric glia")
AnnotationAssertion(rdfs:label obo:CL_4047047 "type I enteric glial cell")
SubClassOf(obo:CL_4047047 obo:CL_4040002)
SubClassOf(obo:CL_4047047 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001809))

# Class: obo:CL_4047048 (type 4 muscularis propria glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasDbXref "PMID:34401661") obo:IAO_0000115 obo:CL_4047048 "An enteric glial cell characterized by a small central soma that extends long, thin, bipolar projections. This cell is primarily located along small nerve fibers within the muscle layers of the gastrointestinal tract and is known for its unbranching processes that closely follow these nerve fibers in the muscularis.")
AnnotationAssertion(terms:contributor obo:CL_4047048 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047048 "2025-02-18T11:14:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34401661") oboInOwl:hasRelatedSynonym obo:CL_4047048 "intramuscular glia")
AnnotationAssertion(rdfs:label obo:CL_4047048 "type 4 muscularis propria glia")
SubClassOf(obo:CL_4047048 obo:CL_4040002)
SubClassOf(obo:CL_4047048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006660))

# Class: obo:CL_4047051 (small intestine BEST4+ enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047051 "An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels.  These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium.")
AnnotationAssertion(terms:contributor obo:CL_4047051 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047051 "2024-07-25T13:05:50Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047051 "small intestine BEST4+ enterocyte")
EquivalentClasses(obo:CL_4047051 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902) ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q8NFU0)))
SubClassOf(obo:CL_4047051 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_4047052 (BEST4+ colonocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047052 "An enterocyte of the human colon expressing bestrophin-4 (BEST4) calcium-activated ion channels.  These cells have a distinct transcriptomic profile compared to other enterocytes and are scattered through the colon epithelium.")
AnnotationAssertion(terms:contributor obo:CL_4047052 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047052 "2024-07-25T13:21:19Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047052 "BEST4+ colonocyte")
EquivalentClasses(obo:CL_4047052 ObjectIntersectionOf(obo:CL_1000347 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q8NFU0)))

# Class: obo:CL_4047053 (TREM2-positive macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33033253") Annotation(oboInOwl:hasDbXref "PMID:33628208") Annotation(oboInOwl:hasDbXref "PMID:35746551") Annotation(oboInOwl:hasDbXref "PMID:36750615") Annotation(oboInOwl:hasDbXref "PMID:39369473") obo:IAO_0000115 obo:CL_4047053 "A macrophage characterized by high expression of Triggering Receptor Expressed on Myeloid cells 2 (TREM2), found in various tissues including the liver, adipose tissue, bone, gut (Colonna, 2023), and tumor microenvironments, where it is associated with immunosuppressive and anti-inflammatory activity (Colmenares, 2024; Khantakova, 2022). This cell exhibits a distinct gene expression profile in the tumor microenvironment, including overexpression of complement system genes (C1QA, C1QB, C1QC, C3), and SPP1 in both mice and humans (Xiong, 2020; Khantakova, 2022). It is involved in phagocytosis, tissue repair, and modulation of immune responses (Coeho, 2021).")
AnnotationAssertion(terms:contributor obo:CL_4047053 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047053 "2025-03-17T17:20:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39369473") oboInOwl:hasNarrowSynonym obo:CL_4047053 "TREM-2 + resident macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35746551") oboInOwl:hasNarrowSynonym obo:CL_4047053 "TREM2+ macrophage")
AnnotationAssertion(rdfs:label obo:CL_4047053 "TREM2-positive macrophage")
EquivalentClasses(obo:CL_4047053 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000016626)))

# Class: obo:CL_4047054 (migratory dendritic cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28845904") Annotation(oboInOwl:hasDbXref "PMID:33681216") Annotation(oboInOwl:hasDbXref "PMID:34302064") obo:IAO_0000115 obo:CL_4047054 "A dendritic cell capable of capturing antigens in peripheral tissues and migrating through blood or lymphatic vessels to secondary lymphoid organs, where it presents processed antigens to T cells. It expresses MHC class II molecules and lacks lineage markers associated with other leukocyte populations, distinguishing it as a member of the dendritic cell lineage. This cell plays a pivotal role in initiating and regulating adaptive immune responses by linking peripheral antigen capture with T cell activation in lymphoid tissues.")
AnnotationAssertion(terms:contributor obo:CL_4047054 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047054 "2025-03-17T17:37:37Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047054 "migratory dendritic cell")
SubClassOf(obo:CL_4047054 obo:CL_0000451)
SubClassOf(obo:CL_4047054 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002407))
SubClassOf(obo:CL_4047054 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002468))

# Class: obo:CL_4047056 (large mucus secreting cholangiocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15579435") Annotation(oboInOwl:hasDbXref "PMID:26273695") Annotation(oboInOwl:hasDbXref "PMID:28261592") Annotation(oboInOwl:hasDbXref "doi:10.1002/hep.25595") Annotation(oboInOwl:hasDbXref "doi:10.1152/ajpgi.00227.2012") obo:IAO_0000115 obo:CL_4047056 "A columnar, mucin-producing cholangiocyte that lines large bile ducts, including the hilar bile duct, right and left hepatic bile ducts, and large intrahepatic bile ducts. This cell expresses phosphorylated STAT3 and TFF-3 in humans and mice.")
AnnotationAssertion(terms:contributor obo:CL_4047056 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047056 "2025-03-20T14:21:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1152/ajpgi.00227.2012") oboInOwl:hasNarrowSynonym obo:CL_4047056 "mucin-secreting cholangiocyte")
AnnotationAssertion(rdfs:label obo:CL_4047056 "large mucus secreting cholangiocyte")
SubClassOf(obo:CL_4047056 obo:CL_1000488)
SubClassOf(obo:CL_4047056 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_4047060 (BAG3-positive monocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20018251") Annotation(oboInOwl:hasDbXref "doi:10.21203/rs.3.rs-3229780/v1") obo:IAO_0000115 obo:CL_4047060 "A circulating mononuclear phagocyte characterized by the expression of BCL-2-associated athanogene 3 (BAG3) protein, a co-chaperone involved in protein quality control and anti-apoptotic processes. (Fontanella, 2009). It undergoes cellular stress during the differentiation into M2 macrophages and is linked to poor survival rates in multiple cancer types. (Park, 2023)")
AnnotationAssertion(terms:contributor obo:CL_4047060 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047060 "2025-05-06T14:41:24Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.21203/rs.3.rs-3229780/v1") oboInOwl:hasExactSynonym obo:CL_4047060 "BAG3+ monocyte")
AnnotationAssertion(rdfs:label obo:CL_4047060 "BAG3-positive monocyte")
EquivalentClasses(obo:CL_4047060 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000004621)))

# Class: obo:CL_4047101 (liver-resident natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26330348") Annotation(oboInOwl:hasDbXref "PMID:26639736") Annotation(oboInOwl:hasDbXref "PMID:27798170") Annotation(oboInOwl:hasDbXref "PMID:31114585") Annotation(oboInOwl:hasDbXref "PMID:32351704") Annotation(oboInOwl:hasDbXref "PMID:34230995") Annotation(oboInOwl:hasDbXref "PMID:35865550") obo:IAO_0000115 obo:CL_4047101 "A natural killer cell resident to the liver, located in the hepatic sinusoids. In humans this cell type is distinguished from circulating natural killer cells by CD49a or CD69 gene expression. Liver-resident natural killer cells have also been shown to express CCR5, EOMES, KLRB1, GZMK, and CXCR6 in humans.")
AnnotationAssertion(terms:contributor obo:CL_4047101 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:contributor obo:CL_4047101 "https://orcid.org/0000-0001-8134-3037")
AnnotationAssertion(terms:date obo:CL_4047101 "2024-07-29T13:43:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31114585") oboInOwl:hasExactSynonym obo:CL_4047101 "he-NK")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fimmu.2019.00946") oboInOwl:hasExactSynonym obo:CL_4047101 "hepatic NK")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.3389/fimmu.2019.00946") oboInOwl:hasExactSynonym obo:CL_4047101 "hepatic natural killer cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33828559") oboInOwl:hasExactSynonym obo:CL_4047101 "intrahepatic NK")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26639736") oboInOwl:hasExactSynonym obo:CL_4047101 "liver NK cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26330348") oboInOwl:hasExactSynonym obo:CL_4047101 "liver resident natural killer cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4047101 "liver-specific natural killer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35726345") oboInOwl:hasExactSynonym obo:CL_4047101 "lr-NK")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34230995") rdfs:comment obo:CL_4047101 "Liver-resident natural killer cells play a crucial role in modulating the immune response during inflammation by balancing cytotoxic activity and cytokine production, thereby contributing to the maintenance of liver homeostasis and protection against excessive tissue damage.")
AnnotationAssertion(rdfs:label obo:CL_4047101 "liver-resident natural killer cell")
EquivalentClasses(obo:CL_4047101 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281)))

# Class: obo:CL_4052001 (multiciliated ependymal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25045600") Annotation(oboInOwl:hasDbXref "PMID:28067220") Annotation(oboInOwl:hasDbXref "PMID:37008045") obo:IAO_0000115 obo:CL_4052001 "An ependymal cell that lines the lateral, third, and fourth ventricles of the brain. The cell is characterized by multiple motile cilia on its apical surface, which beats in a coordinated manner to facilitate the movement of cerebrospinal fluid (CSF), contributing to brain homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4052001 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052001 "2024-08-20T10:06:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25045600") oboInOwl:hasBroadSynonym obo:CL_4052001 "multiciliated ependymal cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28067220") Annotation(oboInOwl:hasDbXref "PMID:37008045") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052001 "E1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25045600") Annotation(oboInOwl:hasDbXref "PMID:27311928") rdfs:comment obo:CL_4052001 "multiciliated ependymal cell, with an average of 16 motile cilia per cell, exhibits two types of planar cell polarity (PCP): rotational polarity, with unidirectional cilia orientation, and translational polarity, with asymmetric cilia positioning in the apical area. This location-specific PCP varies across the ventricular wall, aligning with the direction of CSF flow. These cells are interconnected by adherens and gap junctions, which support intercellular communication and maintain the structural integrity of the ependymal layer. Unlike some other cell types, these cells lack tight junctions.")
AnnotationAssertion(rdfs:label obo:CL_4052001 "multiciliated ependymal cell")
EquivalentClasses(obo:CL_4052001 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004670) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031514) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0010007)))

# Class: obo:CL_4052002 (syncytial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20851884") Annotation(oboInOwl:hasDbXref "Wikipedia:Syncytium") obo:IAO_0000115 obo:CL_4052002 "A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm.")
AnnotationAssertion(terms:contributor obo:CL_4052002 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052002 "2024-08-15T10:38:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "WBbt:0008074") oboInOwl:hasExactSynonym obo:CL_4052002 "syncytium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9067520") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052002 "SC")
AnnotationAssertion(rdfs:label obo:CL_4052002 "syncytial cell")
EquivalentClasses(obo:CL_4052002 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0000768)))

# Class: obo:CL_4052003 (intestinal villus capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18480313") Annotation(oboInOwl:hasDbXref "PMID:35810168") Annotation(oboInOwl:hasDbXref "PMID:38051275") obo:IAO_0000115 obo:CL_4052003 "A capillary endothelial cell that is part of the intestinal villus. This cell is highly fenestrated, with fenestrations most numerous at the villus tips, and plays a vital role in nutrient absorption and maintaining the selective permeability of the intestinal barrier.")
AnnotationAssertion(terms:contributor obo:CL_4052003 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052003 "2024-09-17T10:03:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35810168") oboInOwl:hasBroadSynonym obo:CL_4052003 "villus blood capillary endothelial cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38051275") oboInOwl:hasRelatedSynonym obo:CL_4052003 "villus tip endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052003 "intestinal villus capillary endothelial cell")
EquivalentClasses(obo:CL_4052003 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001213)))
SubClassOf(obo:CL_4052003 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052004 (intestinal fibroblastic reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33707780") Annotation(oboInOwl:hasDbXref "PMID:35440118") obo:IAO_0000115 obo:CL_4052004 "A specialized fibroblastic reticular cell that is part of gut-associated lymphoid tissue (GALT), responsible for forming a structural network that facilitates immune cell interactions. This cell is found in Peyer's patches, cryptopatches, and isolated lymphoid follicles. It plays crucial roles in maintaining intestinal immunity by controlling innate lymphoid cell homeostasis and function, organizing lymphoid structures, and contributing to intestinal microbiome balance.")
AnnotationAssertion(terms:contributor obo:CL_4052004 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052004 "2024-09-19T11:22:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33707780") Annotation(oboInOwl:hasDbXref "PMID:35440118") terms:description obo:CL_4052004 "Intestinal fibroblastic reticular cells develop from both perivascular and subepithelial progenitors during Peyer's patch formation. Intestinal fibroblastic reticular cells express key markers such as CCL19, CCL21, CXCL13, TNFSF13B (also known as BAFF), and produce IL-7, which are important for their immune regulatory functions and the organization of lymphoid structures.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35440118") oboInOwl:hasNarrowSynonym obo:CL_4052004 "Ccl19-expressing fibroblastic reticular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35440118") oboInOwl:hasNarrowSynonym obo:CL_4052004 "solitary intestinal lymphoid tissue fibroblastic reticular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35440118") oboInOwl:hasRelatedSynonym obo:CL_4052004 "gut-associated secondary lymphoid organs fibroblastic reticular cell")
AnnotationAssertion(rdfs:label obo:CL_4052004 "intestinal fibroblastic reticular cell")
SubClassOf(obo:CL_4052004 obo:CL_0009101)
SubClassOf(obo:CL_4052004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962))

# Class: obo:CL_4052005 (intestinal subserosal fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23143399") Annotation(oboInOwl:hasDbXref "PMID:26694715") Annotation(oboInOwl:hasDbXref "PMID:38877292") obo:IAO_0000115 obo:CL_4052005 "A fibroblast that is part of the subserosa of intestine. This cell interacts with immune cells and play roles in inflammation and fibrosis. In certain conditions, such as Crohn's disease, subserosal fibroblast may differentiate into myofibroblasts.")
AnnotationAssertion(terms:contributor obo:CL_4052005 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052005 "2024-09-19T12:58:29Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052005 "intestinal subserosal fibroblast")
SubClassOf(obo:CL_4052005 obo:CL_0000057)
SubClassOf(obo:CL_4052005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001243))
SubClassOf(obo:CL_4052005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012375))

# Class: obo:CL_4052006 (intestinal enteroendocrine progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31756561") Annotation(oboInOwl:hasDbXref "PMID:32531023") Annotation(oboInOwl:hasDbXref "PMID:35913117") Annotation(oboInOwl:hasDbXref "PMID:38260422") Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-021-27901-5") obo:IAO_0000115 obo:CL_4052006 "An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs.")
AnnotationAssertion(terms:contributor obo:CL_4052006 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052006 "2024-09-20T12:13:26Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31756561") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052006 "EEC Progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25670791") rdfs:comment obo:CL_4052006 "The EEC progenitor is also present in other organisms; for example, flies have EEC progenitors but lack intestinal crypts and do not express the same markers. Instead, they are Dl+ and Pros+.")
AnnotationAssertion(rdfs:label obo:CL_4052006 "intestinal enteroendocrine progenitor")
SubClassOf(obo:CL_4052006 obo:CL_0002563)
SubClassOf(obo:CL_4052006 obo:CL_0011026)
SubClassOf(obo:CL_4052006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011184))
SubClassOf(obo:CL_4052006 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002250))

# Class: obo:CL_4052007 (subepithelial intestinal fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30270042") Annotation(oboInOwl:hasDbXref "PMID:33430285") Annotation(oboInOwl:hasDbXref "PMID:33916891") Annotation(oboInOwl:hasDbXref "PMID:37080817") obo:IAO_0000115 obo:CL_4052007 "A fibroblast located adjacent to the intestinal epithelium in both the small intestine and colon, specifically around the crypts. This cell is characterized by the expression of  PDGFRα and various collagen isoforms, including COL4A5 and COL4A6. It secretes signalling molecules like TGF-β, Wnt ligands, and BMPs, which are crucial for epithelial homeostasis, intestinal stem cell support, and basement membrane formation.")
AnnotationAssertion(terms:contributor obo:CL_4052007 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052007 "2024-09-23T09:59:27Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30270042") Annotation(oboInOwl:hasDbXref "PMID:33916891") oboInOwl:hasRelatedSynonym obo:CL_4052007 "S2 fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33916891") oboInOwl:hasRelatedSynonym obo:CL_4052007 "S2 mesenchymal cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30270042") Annotation(oboInOwl:hasDbXref "PMID:33916891") Annotation(oboInOwl:hasDbXref "PMID:37495570") rdfs:comment obo:CL_4052007 "The S2 fibroblast population has been identified as a subset of intestinal fibroblasts located near the epithelial lining. This population is divided into two subtypes: S2a and S2b. S2a is involved in epithelial differentiation, while S2b, located at the top of the crypt, regulates intestinal stem cell proliferation, niche formation, and wound healing.")
AnnotationAssertion(rdfs:label obo:CL_4052007 "subepithelial intestinal fibroblast")
SubClassOf(obo:CL_4052007 obo:CL_0000057)
SubClassOf(obo:CL_4052007 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001277))

# Class: obo:CL_4052008 (crypt-bottom fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33916891") Annotation(oboInOwl:hasDbXref "doi:/10.1371/journal.pbio.3001032") obo:IAO_0000115 obo:CL_4052008 "A subepithelial intestinal fibroblast that is located adjacent to the base of the crypt of Lieberkühn, near the intestinal stem cells. Characterized by low PDGFRα expression, this cell is crucial for maintaining the intestinal stem cell niche. Crypt-bottom fibroblast secretes key signaling molecules including canonical Wnt ligands (Wnt2, Wnt2b), Wnt potentiators (Rspo3), and BMP inhibitors (Grem1), which collectively regulate intestinal stem cell function and epithelial homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4052008 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052008 "2024-09-23T10:23:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1371/journal.pbio.3001032") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052008 "CBFs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33916891") oboInOwl:hasRelatedSynonym obo:CL_4052008 "bottom pericryptic-associated fibroblasts")
AnnotationAssertion(rdfs:label obo:CL_4052008 "crypt-bottom fibroblast")
SubClassOf(obo:CL_4052008 obo:CL_4052007)
SubClassOf(obo:CL_4052008 ObjectSomeValuesFrom(obo:RO_0002220 obo:CL_0002250))
SubClassOf(obo:CL_4052008 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0013739))

# Class: obo:CL_4052009 (crypt-top fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33916891") Annotation(oboInOwl:hasDbXref "doi:/10.1371/journal.pbio.3001032") obo:IAO_0000115 obo:CL_4052009 "A subepithelial intestinal fibroblast that is located adjacent to the top of the crypt of Lieberkuhn. Characterized by high experession of PDGFRα, this cell secretes a range of signaling factors, including WNTs and BMPs, that drive epithelial differentiation, creating a gradient that regulates the balance between stem cell maintenance and differentiation.")
AnnotationAssertion(terms:contributor obo:CL_4052009 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052009 "2024-09-23T11:14:04Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1371/journal.pbio.3001032") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052009 "CTFs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37495570") oboInOwl:hasRelatedSynonym obo:CL_4052009 "S2b fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33916891") oboInOwl:hasRelatedSynonym obo:CL_4052009 "top pericryptic fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37495570") rdfs:comment obo:CL_4052009 "S2b fibroblasts are located at the top of the crypt and express NRG1 and NPY.")
AnnotationAssertion(rdfs:label obo:CL_4052009 "crypt-top fibroblast")
SubClassOf(obo:CL_4052009 obo:CL_4052007)
SubClassOf(obo:CL_4052009 ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0013740))

# Class: obo:CL_4052010 (pre-theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20628033") Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasDbXref "PMID:36205477") obo:IAO_0000115 obo:CL_4052010 "A stromal cell that serves as a precursor to the theca cell layers in the ovary growing follicles. This cell is present in the early stages of follicular growth, particularly in smaller follicles. Unlike mature theca cell, a pre-theca cell is initially non-steroidogenic and lacks luteinizing hormone receptors.")
AnnotationAssertion(terms:contributor obo:CL_4052010 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052010 "2024-09-25T11:15:57Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasExactSynonym obo:CL_4052010 "early theca cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") oboInOwl:hasExactSynonym obo:CL_4052010 "progenitor theca cell")
AnnotationAssertion(rdfs:label obo:CL_4052010 "pre-theca cell")
SubClassOf(obo:CL_4052010 obo:CL_0000499)
SubClassOf(obo:CL_4052010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0012186))
SubClassOf(obo:CL_4052010 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000503))

# Class: obo:CL_4052011 (follicle associated enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29339448") Annotation(oboInOwl:hasDbXref "PMID:34634036") Annotation(oboInOwl:hasDbXref "PMID:7107724") obo:IAO_0000115 obo:CL_4052011 "An enterocyte found in the follicle-associated epithelium (FAE) that covers Peyer's patches and other mucosa-associated lymphoid tissues. This cell has reduced absorptive capacity and expresses higher levels of chemokines CCL20 and CXCL16, compared to regular villus enterocytes. It contributes to antigen sampling and immune interactions, supporting the specialized function of the FAE in mucosal immunity.")
AnnotationAssertion(terms:contributor obo:CL_4052011 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052011 "2024-09-25T15:28:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7107724") oboInOwl:hasExactSynonym obo:CL_4052011 "follicle-associated epithelium enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7107724") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052011 "FAE enterocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:7107724") oboInOwl:hasRelatedSynonym obo:CL_4052011 "follicular enterocyte")
AnnotationAssertion(rdfs:label obo:CL_4052011 "follicle associated enterocyte")
SubClassOf(obo:CL_4052011 obo:CL_0000584)
SubClassOf(obo:CL_4052011 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004693))

# Class: obo:CL_4052012 (interna theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15833266") Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasDbXref "PMID:32530882") Annotation(oboInOwl:hasDbXref "Wikipedia:Theca_interna") obo:IAO_0000115 obo:CL_4052012 "A specialized theca cell that forms the inner, highly vascularized layer of the theca surrounding ovarian follicles. Originating from progenitor theca cells, the theca interna cell is steroidogenic, playing a crucial role in the production of androgens, which serves as a precursor for estrogen synthesis in granulosa cells. This cell expresses luteinizing hormone receptors, enabling it to respond to hormonal signals that regulate steroidogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4052012 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052012 "2024-09-30T11:10:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36599970") oboInOwl:hasRelatedSynonym obo:CL_4052012 "androgenic theca cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052012 "inTC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052012 "interna TC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36599970") oboInOwl:hasRelatedSynonym obo:CL_4052012 "steroidogenic theca interna cell")
AnnotationAssertion(rdfs:label obo:CL_4052012 "interna theca cell")
EquivalentClasses(obo:CL_4052012 ObjectIntersectionOf(obo:CL_0000503 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000157)))
SubClassOf(obo:CL_4052012 obo:CL_0000593)
SubClassOf(obo:CL_4052012 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4052010))
DisjointClasses(obo:CL_4052012 obo:CL_4052013)

# Class: obo:CL_4052013 (externa theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasDbXref "PMID:32530882") Annotation(oboInOwl:hasDbXref "PMID:36758341") Annotation(oboInOwl:hasDbXref "Wikipedia:Theca_externa") obo:IAO_0000115 obo:CL_4052013 "A specialized theca cell that forms the outer layer of the theca surrounding the ovarian follicle, appearing at the antral follicle. Originating from progenitor theca cells, theca externa cell is characterized by its fibroblast-like appearance and primarily function to provide structural support to the developing follicle. This cell produces collagen fibers and extracellular matrix components such as Col1a1 and Col1a2.")
AnnotationAssertion(terms:contributor obo:CL_4052013 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052013 "2024-09-30T11:10:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052013 "exTC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31320652") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052013 "externa TC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36599970") oboInOwl:hasRelatedSynonym obo:CL_4052013 "structural theca cell")
AnnotationAssertion(rdfs:label obo:CL_4052013 "externa theca cell")
EquivalentClasses(obo:CL_4052013 ObjectIntersectionOf(obo:CL_0000503 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000156)))
SubClassOf(obo:CL_4052013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4052010))

# Class: obo:CL_4052014 (pancreatic islet capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:27124642") Annotation(oboInOwl:hasDbXref "PMID:28396983") Annotation(oboInOwl:hasDbXref "PMID:33200981") obo:IAO_0000115 obo:CL_4052014 "A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture.")
AnnotationAssertion(terms:contributor obo:CL_4052014 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052014 "2024-09-30T14:36:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:28396983") oboInOwl:hasBroadSynonym obo:CL_4052014 "islet endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") oboInOwl:hasBroadSynonym obo:CL_4052014 "pancreatic islet endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052014 "pancreatic islet capillary endothelial cell")
EquivalentClasses(obo:CL_4052014 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006)))
SubClassOf(obo:CL_4052014 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052015 (endocrine gland capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18480313") obo:IAO_0000115 obo:CL_4052015 "Any capillary endothelial cell that is part of an endocrine gland.")
AnnotationAssertion(terms:contributor obo:CL_4052015 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052015 "2024-09-30T15:27:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052015 "endocrine gland capillary endothelial cell")
EquivalentClasses(obo:CL_4052015 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002368)))

# Class: obo:CL_4052016 (pituitary gland capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10810312") Annotation(oboInOwl:hasDbXref "PMID:32910242") obo:IAO_0000115 obo:CL_4052016 "A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling.")
AnnotationAssertion(terms:contributor obo:CL_4052016 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052016 "2024-09-30T15:31:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:4899902") rdfs:comment obo:CL_4052016 "In the anterior pituitary gland of rats, capillary endothelial cells are distinguished by numerous fenestrations, which are covered by a single-layered diaphragm. The diaphragm features a dense ring-like structure.")
AnnotationAssertion(rdfs:label obo:CL_4052016 "pituitary gland capillary endothelial cell")
EquivalentClasses(obo:CL_4052016 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000007)))
SubClassOf(obo:CL_4052016 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052017 (choroid plexus capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18480313") Annotation(oboInOwl:hasDbXref "PMID:32375819") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/books/NBK27998/") obo:IAO_0000115 obo:CL_4052017 "A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF).")
AnnotationAssertion(terms:contributor obo:CL_4052017 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052017 "2024-10-01T11:38:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052017 "choroid plexus capillary endothelial cell")
EquivalentClasses(obo:CL_4052017 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001886)))
SubClassOf(obo:CL_4052017 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052018 (fallopian tube epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Fallopian_tube") obo:IAO_0000115 obo:CL_4052018 "Any epithelial cell that is part of the fallopian tube.")
AnnotationAssertion(terms:contributor obo:CL_4052018 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052018 "2024-10-01T12:09:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Fallopian_tube") oboInOwl:hasBroadSynonym obo:CL_4052018 "oviduct epithelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Fallopian_tube") oboInOwl:hasExactSynonym obo:CL_4052018 "uterine tube epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052018 "fallopian tube epithelial cell")
EquivalentClasses(obo:CL_4052018 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889)))

# Class: obo:CL_4052019 (fallopian tube non-ciliated epithelial cell)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4052019 "Any epithelial cell that is part of the fallopian tube and lacks cilia.")
AnnotationAssertion(terms:contributor obo:CL_4052019 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052019 "2024-10-01T12:12:12Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052019 "fallopian tube non-ciliated cell")
AnnotationAssertion(rdfs:label obo:CL_4052019 "fallopian tube non-ciliated epithelial cell")
SubClassOf(obo:CL_4052019 obo:CL_0000066)
SubClassOf(obo:CL_4052019 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889))
SubClassOf(obo:CL_4052019 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005929))

# Class: obo:CL_4052020 (lung resident granzyme K-associated CD8 T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.06.17.496207") obo:IAO_0000115 obo:CL_4052020 "A granzyme K-associated CD8 T cell that resides in the lung, characterized by the expression of granzyme K (GZMK), and tissue residency markers CD103 and CD49a. This cell exhibits cytotoxic potential through its expression of multiple granzymes (GZMA, GZMB, GZMH, GZMM) in addition to GZMK.")
AnnotationAssertion(terms:contributor obo:CL_4052020 <https://orcid.org/0000-0002-2336-2552>)
AnnotationAssertion(terms:contributor obo:CL_4052020 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052020 "2024-10-14T15:42:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.06.17.496207") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052020 "lung resident CD8-GZMK")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28322863") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.06.17.496207") rdfs:comment obo:CL_4052020 "Lung resident granzyme K-associated CD8 T cell represents an intermediate stage of T cell differentiation, with GZMK expression peaking during this phase.")
AnnotationAssertion(rdfs:label obo:CL_4052020 "lung resident granzyme K-associated CD8 T cell")
EquivalentClasses(obo:CL_4052020 ObjectIntersectionOf(obo:CL_4033040 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003472)))

# Class: obo:CL_4052021 (granzyme K-associated CD8 T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35704599") Annotation(oboInOwl:hasDbXref "PMID:37449888") obo:IAO_0000115 obo:CL_4052021 "A CD8 T cell characterized by high expression of Granzyme K (GZMK). This cell is enriched in both inflamed tissues, such as synovial tissue in rheumatoid arthritis and respiratory tissues during COVID-19, as well as non-inflamed tissues like the gut and kidneys. Unlike highly cytotoxic GZMB+ CD8+ T cell, GZMK+ CD8+ T cell exhibits lower direct cytotoxic potential, and is involved in producing pro-inflammatory cytokines such as IFN-γ and TNF-α.")
AnnotationAssertion(terms:contributor obo:CL_4052021 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052021 "2024-10-18T09:51:48Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35704599") oboInOwl:hasExactSynonym obo:CL_4052021 "granzyme K+ CD8 T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35704599") oboInOwl:hasExactSynonym obo:CL_4052021 "tissue-enriched expressing GzmK CD8 cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36347862") oboInOwl:hasNarrowSynonym obo:CL_4052021 "GZMK high CD8+ T effector memory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.06.17.496207") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052021 "CD8-GZMK cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35704599") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052021 "TteK CD8 cell")
AnnotationAssertion(rdfs:label obo:CL_4052021 "granzyme K-associated CD8 T cell")
EquivalentClasses(obo:CL_4052021 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003472)))

# Class: obo:CL_4052022 (fallopian tube smooth muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31183831") Annotation(oboInOwl:hasDbXref "PMID:31613440") obo:IAO_0000115 obo:CL_4052022 "A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus.")
AnnotationAssertion(terms:contributor obo:CL_4052022 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052022 "2024-10-21T12:16:54Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31613440") oboInOwl:hasBroadSynonym obo:CL_4052022 "oviduct smooth muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31613440") oboInOwl:hasExactSynonym obo:CL_4052022 "uterine tube smooth muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18621753") rdfs:comment obo:CL_4052022 "The fallopian tube smooth muscle cell in the human contracts dynamically in response to hormones and signaling molecules. Prostaglandins, particularly PGF2α and PGE2, have been shown to increase muscular contractions, while progesterone, levonorgestrel, mifepristone, oxytocin, and human chorionic gonadotropin (hCG) decrease them. These contractile responses are crucial for regulating gamete and embryo transport through the fallopian tube.")
AnnotationAssertion(rdfs:label obo:CL_4052022 "fallopian tube smooth muscle cell")
EquivalentClasses(obo:CL_4052022 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889)))

# Class: obo:CL_4052023 (luminal endometrial unciliated epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32929266") Annotation(oboInOwl:hasDbXref "PMID:36581776") Annotation(oboInOwl:hasDbXref "PMID:38559249") Annotation(oboInOwl:hasDbXref "PMID:39198675") obo:IAO_0000115 obo:CL_4052023 "An epithelial cell that is part of the endometrial luminal epithelium, forming a continuous layer lining the uterine cavity. This cell undergoes cyclical changes during the menstrual cycle, proliferating under estrogen in the proliferative phase, and differentiating under progesterone in the secretory phase to prepare for potential implantation. During the window of implantation, this cell changes from a tall columnar shape to a shorter columnar or cuboidal form, loses polarity, and becomes receptive to blastocyst implantation.")
AnnotationAssertion(terms:contributor obo:CL_4052023 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052023 "2024-10-22T12:02:23Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") rdfs:comment obo:CL_4052023 "The luminal endometrial unciliated epithelial cell expresses WNT7A, and LGR5 during the proliferative phase, transitioning to express VTCN1 and SULT1E1 in the early secretory phase, and LEFTY1, IL6, and PTGS1 in the mid- to late-secretory phases.")
AnnotationAssertion(rdfs:label obo:CL_4052023 "luminal endometrial unciliated epithelial cell")
EquivalentClasses(obo:CL_4052023 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011949) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940)))

# Class: obo:CL_4052024 (myotendinous junction nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33311457") Annotation(oboInOwl:hasDbXref "PMID:33311464") Annotation(oboInOwl:hasDbXref "PMID:38398025") obo:IAO_0000115 obo:CL_4052024 "A specialized muscle nucleus that is part of an extrafusal muscle fiber and overlaps the muscle-tendon junction, where muscle fibers connect to tendons. Characterized by a distinct transcriptional profile with the expression of genes like COL22A1, this myonucleus supports the structural integrity and function of the junction, playing a key role in transmitting the force generated by muscle contraction to the tendon.")
AnnotationAssertion(terms:contributor obo:CL_4052024 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:contributor obo:CL_4052024 <https://orcid.org/0009-0001-6947-615X>)
AnnotationAssertion(terms:date obo:CL_4052024 "2024-10-30T13:47:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33311464") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasExactSynonym obo:CL_4052024 "myotendinous junction myonuclei")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33311457") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasExactSynonym obo:CL_4052024 "myotendinous junction nuclei")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052024 "MTJ nucleus")
AnnotationAssertion(rdfs:label obo:CL_4052024 "myotendinous junction nucleus")
EquivalentClasses(obo:CL_4052024 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:BFO_0000050 obo:CL_0008046) ObjectSomeValuesFrom(obo:RO_0002131 obo:GO_0005927)))

# Class: obo:CL_4052025 (neuromuscular junction nucleus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33037211") Annotation(oboInOwl:hasDbXref "PMID:33311457") Annotation(oboInOwl:hasDbXref "PMID:33311464") obo:IAO_0000115 obo:CL_4052025 "A specialized muscle nucleus that is part of an extrafusal muscle fiber, clustered at the postsynaptic side of the neuromuscular junction. This nucleus exhibits a distinct transcriptional profile, including acetylcholine receptor (AChR) subunit genes. It regulates the production of proteins essential for maintaining the structure and function of the neuromuscular junction, supporting efficient nerve-muscle signaling for muscle contraction.")
AnnotationAssertion(terms:contributor obo:CL_4052025 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:contributor obo:CL_4052025 <https://orcid.org/0009-0001-6947-615X>)
AnnotationAssertion(terms:date obo:CL_4052025 "2024-10-31T11:09:04Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33311464") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasExactSynonym obo:CL_4052025 "neuromuscular junction myonuclei")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33311457") Annotation(oboInOwl:hasSynonymType obo:OMO_0003004) oboInOwl:hasExactSynonym obo:CL_4052025 "neuromuscular junction nuclei")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052025 "NMJ nuclues")
AnnotationAssertion(rdfs:label obo:CL_4052025 "neuromuscular junction nucleus")
EquivalentClasses(obo:CL_4052025 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:BFO_0000050 obo:CL_0008046) ObjectSomeValuesFrom(obo:RO_0002131 obo:GO_0098522)))

# Class: obo:CL_4052026 (type IIx muscle cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") Annotation(oboInOwl:hasDbXref "PMID:35908794") Annotation(oboInOwl:hasDbXref "PMID:36361732") Annotation(oboInOwl:hasDbXref "doi:10.1101/2024.05.15.594276") obo:IAO_0000115 obo:CL_4052026 "A fast type II muscle cell that is part of the skeletal muscle tissue. This cell is characterized by its intermediate metabolic profile, utilizing both glycolytic and oxidative pathways for energy production. In humans, it is distinguished by the expression of myosin heavy chain 1 (MYH1).")
AnnotationAssertion(terms:contributor obo:CL_4052026 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052026 "2024-11-04T10:26:29Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") oboInOwl:hasExactSynonym obo:CL_4052026 "type 2x fiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") oboInOwl:hasExactSynonym obo:CL_4052026 "type 2x muscle cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") oboInOwl:hasExactSynonym obo:CL_4052026 "type 2x muscle fiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2024.05.15.594276") oboInOwl:hasExactSynonym obo:CL_4052026 "type IIx muscle fiber")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27199166") Annotation(oboInOwl:hasDbXref "PMID:34727990") rdfs:comment obo:CL_4052026 "In humans, type IIx fiber contains high levels of MYLK2, enhancing contraction speed and force via myosin phosphorylation, especially under low calcium. This mechanism supports post-activation potentiation, increasing force output in fast-twitch muscles. Additionally, this fiber has abundant ACTN3 (α-actinin-3), linked to muscle power, and exhibits the highest shortening velocity among human muscle fiber types. Notably, type IIx fiber is selectively lost in aging-related sarcopenia, increases in proportion in type 2 diabetes and obesity, and is the first to degenerate in Duchenne Muscular Dystrophy, impacting muscle function across various conditions.")
AnnotationAssertion(rdfs:label obo:CL_4052026 "type IIx muscle cell")
SubClassOf(obo:CL_4052026 obo:CL_0002212)
SubClassOf(obo:CL_4052026 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134))

# Class: obo:CL_4052027 (atretic theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20628033") Annotation(oboInOwl:hasDbXref "PMID:38069168") obo:IAO_0000115 obo:CL_4052027 "A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4052027 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052027 "2024-11-06T10:10:51Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38069168") rdfs:comment obo:CL_4052027 "During atresia, theca interna and externa cells undergo distinct morphological and functional changes. Theca interna cells round up, expand in cytoplasmic area, and thicken the internal layer as organization degrades, while showing reduced STAR expression, which lowers androgen production. Theca externa cells display decreased ACTA2 expression, weakening structural integrity.")
AnnotationAssertion(rdfs:label obo:CL_4052027 "atretic theca cell")
SubClassOf(obo:CL_4052027 obo:CL_4033089)
SubClassOf(obo:CL_4052027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000503))

# Class: obo:CL_4052028 (uterine natural killer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35720413") Annotation(oboInOwl:hasDbXref "PMID:39198675") Annotation(oboInOwl:hasDbXref "Wikipedia:Uterine_natural_killer_cells") obo:IAO_0000115 obo:CL_4052028 "A natural killer cell that is part of the uterus, specifically within the endometrium during the non-pregnant state and in the decidua during pregnancy. This cell exhibits dynamic changes in frequency throughout the menstrual cycle, with lower levels during menstruation and a significant increase during the mid-secretory phase and early pregnancy.")
AnnotationAssertion(terms:contributor obo:CL_4052028 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052028 "2024-11-15T10:12:40Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35720413") oboInOwl:hasNarrowSynonym obo:CL_4052028 "endometrial natural killer cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052028 "uNK cell")
AnnotationAssertion(rdfs:label obo:CL_4052028 "uterine natural killer cell")
EquivalentClasses(obo:CL_4052028 ObjectIntersectionOf(obo:CL_0000623 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000995)))

# Class: obo:CL_4052029 (subpleural fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36543915") Annotation(oboInOwl:hasDbXref "PMID:36769178") Annotation(oboInOwl:hasDbXref "PMID:37291214") obo:IAO_0000115 obo:CL_4052029 "A fibroblast that is located beneath the visceral pleura of the lung. This cell contributes to the development of idiopathic pulmonary fibrosis (IPF) by forming fibrotic lesions that originate subpleurally and extend into lung tissue through activation, proliferation, migration, and differentiation into a myofibroblast.")
AnnotationAssertion(terms:contributor obo:CL_4052029 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052029 "2024-11-29T13:54:15Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052029 "subpleural fibroblast")
SubClassOf(obo:CL_4052029 obo:CL_0000057)
SubClassOf(obo:CL_4052029 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048))

# Class: obo:CL_4052030 (adventitial fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28705796") Annotation(oboInOwl:hasDbXref "PMID:36718802") obo:IAO_0000115 obo:CL_4052030 "A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression")
AnnotationAssertion(terms:contributor obo:CL_4052030 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052030 "2024-12-05T11:01:15Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36718802") rdfs:comment obo:CL_4052030 "Single-cell transcriptomics of murine aorta identifies two adventitial fibroblast-specific markers, PDGFRA and DPEP1, which were validated at the protein level by immunohistochemistry and flow cytometry across human and murine arteries, highlighting fibroblast heterogeneity in health and cardiovascular disease (CVD) in humans and mice.")
AnnotationAssertion(rdfs:label obo:CL_4052030 "adventitial fibroblast")
EquivalentClasses(obo:CL_4052030 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005734)))
SubClassOf(obo:CL_4052030 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816))
SubClassOf(obo:CL_4052030 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))

# Class: obo:CL_4052031 (respiratory airway secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35355013") Annotation(oboInOwl:hasDbXref "PMID:36796082") obo:IAO_0000115 obo:CL_4052031 "A secretory epithelial cell of the respiratory and terminal bronchioles.")
AnnotationAssertion(terms:contributor obo:CL_4052031 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052031 "2024-11-29T16:14:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36796082") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052031 "RAS cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35355018") oboInOwl:hasRelatedSynonym obo:CL_4052031 "terminal and respiratory bronchioles secretory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35355013") Annotation(oboInOwl:hasDbXref "PMID:36796082") rdfs:comment obo:CL_4052031 "The respiratory airway secretory cell is cuboidal and has a unique transcriptomic profile compared to other epithelial cells in the same region. In humans, it functions as a multipotent progenitor, capable of regenerating alveolar type 2 (AT2) cells.")
AnnotationAssertion(rdfs:label obo:CL_4052031 "respiratory airway secretory cell")
SubClassOf(obo:CL_4052031 obo:CL_1100001)
SubClassOf(obo:CL_4052031 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002051))

# Class: obo:CL_4052032 (granzyme H-associated CD8 T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") obo:IAO_0000115 obo:CL_4052032 "A CD8 T cell characterized by high expression of Granzyme H (GZMH). This cell exhibits a restricted TCR repertoire and elevated expression of cytotoxic, exhaustion, and type I interferon-stimulated gene signatures compared to controls.")
AnnotationAssertion(terms:contributor obo:CL_4052032 <https://orcid.org/0000-0002-3958-7465>)
AnnotationAssertion(terms:contributor obo:CL_4052032 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052032 "2025-01-10T10:14:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") oboInOwl:hasExactSynonym obo:CL_4052032 "granzyme H+ CD8 T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052032 "GZMH+ CD8+ T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment obo:CL_4052032 "This cell type is significantly expanded in systemic lupus erythematosus (SLE) patients. Unlike other CD8 T cell populations, GZMH+ CD8 T cells can comprise up to 50% of all lymphocytes in some SLE patients.")
AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell")
EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490)))

# Class: obo:CL_4052033 (biliary tuft cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35245089") Annotation(oboInOwl:hasDbXref "PMID:37863104") obo:IAO_0000115 obo:CL_4052033 "A tuft cell that is part of the extrahepatic biliary tree, including the gallbladder and extrahepatic bile ducts. It shares a core genetic program with intestinal tuft cells but has unique tissue-specific genes. Biliary tuft cell functions as a bile acid-sensitive regulator, suppressing inflammation and modulating microbiome-dependent neutrophil infiltration in biliary tissues. Unlike its intestinal counterparts, this cell decreases in number postnatally as bile acid production matures, with its abundance negatively regulated by bile acids.")
AnnotationAssertion(terms:contributor obo:CL_4052033 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052033 "2025-01-20T14:39:06Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35245089") oboInOwl:hasExactSynonym obo:CL_4052033 "gallbladder/extrahepatic bile duct tuft cell")
AnnotationAssertion(rdfs:label obo:CL_4052033 "biliary tuft cell")
SubClassOf(obo:CL_4052033 obo:CL_0002204)
SubClassOf(obo:CL_4052033 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050728))

# Class: obo:CL_4052034 (tuft cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30022164") Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "PMID:35668088") Annotation(oboInOwl:hasDbXref "PMID:36351364") Annotation(oboInOwl:hasDbXref "PMID:36961668") obo:IAO_0000115 obo:CL_4052034 "A tuft cell that is part of the medullary epithelium of the thymus, characterized by lateral microvilli and specific markers, including L1CAM in both mice (Zhang et al., 2022) and humans (Sun et al., 2023), as well as MHC II in mice (Miller et al., 2018). This cell is pivotal in immune functions such as antigen presentation, central tolerance, and type 2 immunity. A tuft cell in the thymus exhibits characteristics of both a medullary thymic epithelial cell (mTEC) and a peripheral tuft cell. Its development is governed by transcription factors such as POU2F3.")
AnnotationAssertion(terms:contributor obo:CL_4052034 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052034 "2025-01-16T11:29:54Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") oboInOwl:hasExactSynonym obo:CL_4052034 "thymic tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") rdfs:comment obo:CL_4052034 "A thymic tuft cell is a subset of terminally differentiated medullary thymic epithelial cell comprising 5-10% of total mTECs. Lineage-tracing studies indicate that this cell arises from mature MHCII mTECs, with development occurring through both Aire-dependent and Aire-independent pathways. However, its exact origins remain unclear.")
AnnotationAssertion(rdfs:label obo:CL_4052034 "tuft cell of thymus")
EquivalentClasses(obo:CL_4052034 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003846)))
SubClassOf(obo:CL_4052034 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124))
SubClassOf(obo:CL_4052034 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002491))

# Class: obo:CL_4052035 (tuft cell of pancreatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "PMID:32717220") obo:IAO_0000115 obo:CL_4052035 "A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence.")
AnnotationAssertion(terms:contributor obo:CL_4052035 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052035 "2025-01-16T11:50:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9749964") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic brush cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32717220") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic tuft cell")
AnnotationAssertion(rdfs:label obo:CL_4052035 "tuft cell of pancreatic duct")
EquivalentClasses(obo:CL_4052035 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009970)))

# Class: obo:CL_4052036 (tuft cell of nasal cavity)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30379593") Annotation(oboInOwl:hasDbXref "PMID:38306414") obo:IAO_0000115 obo:CL_4052036 "A tuft cell that is part of the nasal cavity epithelium, located in both the respiratory and olfactory epithelia of the nose. This cell plays key roles in chemosensation, lipid mediator production, immune responses, and epithelial homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4052036 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052036 "2025-01-21T09:04:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34692913") oboInOwl:hasExactSynonym obo:CL_4052036 "nasal brush cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasExactSynonym obo:CL_4052036 "nasal tuft cell")
AnnotationAssertion(rdfs:label obo:CL_4052036 "tuft cell of nasal cavity")
EquivalentClasses(obo:CL_4052036 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005384)))

# Class: obo:CL_4052037 (tuft cell of olfactory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.09.26.509561") obo:IAO_0000115 obo:CL_4052037 "A tuft cell that is part of the olfactory epithelium, characterized by a globular body and the expression of neurogranin (Nrgn) in mice. This cell plays a crucial role in allergen recognition and regulating olfactory stem cell proliferation via TRPM5-dependent ATP sensing and cysteinyl leukotriene production. Unlike nasal respiratory tuft cells, it has low to absent expression of taste receptors, including the G protein Gα gustducin, and rarely contacts olfactory sensory neurons directly.")
AnnotationAssertion(terms:contributor obo:CL_4052037 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052037 "2025-02-06T15:03:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasExactSynonym obo:CL_4052037 "olfactory tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052037 "TPRM5+ tuft-MVC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052037 "TRPM5+ microvillous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.09.26.509561") oboInOwl:hasRelatedSynonym obo:CL_4052037 "TRPM5+ microvillous tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052037 "tuft-microvillous cell")
AnnotationAssertion(rdfs:label obo:CL_4052037 "tuft cell of olfactory epithelium")
EquivalentClasses(obo:CL_4052037 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
SubClassOf(obo:CL_4052037 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0072091))

# Class: obo:CL_4052038 (tuft cell of nasal cavity respiratory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30379593") Annotation(oboInOwl:hasDbXref "PMID:34932383") Annotation(oboInOwl:hasDbXref "PMID:38306414") obo:IAO_0000115 obo:CL_4052038 "A tuft cell that is part of the nasal cavity respiratory epithelium. Acting as a chemosensor, it detects bitter taste ligands and bacterial signals via taste receptors, maintaining epithelial-microbial homeostasis by stimulating antimicrobial peptide secretion from adjacent epithelial cells. This cell is a major source of IL-25, promoting type 2 immune responses and potentially contributing to chronic rhinosinusitis (O'Leary et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4052038 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052038 "2025-02-06T15:28:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "Gɑ-gustducin high respiratory tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "nasal respiratory solitary chemosensory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "tuft-solitary chemosensory cell")
AnnotationAssertion(rdfs:label obo:CL_4052038 "tuft cell of nasal cavity respiratory epithelium")
EquivalentClasses(obo:CL_4052038 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005385)))

# Class: obo:CL_4052039 (tuft cell of submandibular gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35993302") Annotation(oboInOwl:hasDbXref "PMID:38098741") Annotation(oboInOwl:hasDbXref "PMID:8874101") obo:IAO_0000115 obo:CL_4052039 "A tuft cell that is part of the epithelium of the submandibular gland, localized to the striated ducts in mice, pigs, and humans, and to the main excretory ducts in rats. This cell is characterized by chemosensory functions, potential roles in immune regulation, and possible involvement in salivary secretion via acetylcholine release.")
AnnotationAssertion(terms:contributor obo:CL_4052039 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052039 "2025-02-12T10:38:11Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052039 "tuft cell of submandibular gland")
EquivalentClasses(obo:CL_4052039 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003359)))

# Class: obo:CL_4052040 (tuft cell of stomach)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") Annotation(oboInOwl:hasDbXref "PMID:38117182") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.02.16.480779") obo:IAO_0000115 obo:CL_4052040 "A tuft cell that is part of the epithelium of the stomach. This cell is characterized by gastric chemosensation and immune regulation through IL-25 secretion, which activates ILC2s to produce IL-13, driving epithelial remodelling and tuft cell expansion. Unlike intestinal tuft cells, which are primarily involved in helminth defense and type 2 immunity, the tuft cell of the stomach is primarily involved in inflammation, metaplasia, and hyperplasia.")
AnnotationAssertion(terms:contributor obo:CL_4052040 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052040 "2025-02-12T11:24:56Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38117182") oboInOwl:hasExactSynonym obo:CL_4052040 "gastric tuft cell")
AnnotationAssertion(rdfs:label obo:CL_4052040 "tuft cell of stomach")
EquivalentClasses(obo:CL_4052040 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276)))

# Class: obo:CL_4052041 (tuft cell of auditory tube)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30379593") Annotation(oboInOwl:hasDbXref "PMID:32733896") obo:IAO_0000115 obo:CL_4052041 "A tuft cell that is part of the epithelium of the pharyngotympanic (auditory) tube. This chemosensory cell is often positioned near cholinoreceptive sensory nerve fibers, suggesting a role in neuroimmune communication. It detects chemical signals and releases neuropeptides, such as acetylcholine (ACh) and CGRP, which contribute to inflammatory responses that help protect deeper tissues from harmful substances.")
AnnotationAssertion(terms:contributor obo:CL_4052041 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052041 "2025-02-12T12:00:10Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052041 "tuft cell of auditory tube")
EquivalentClasses(obo:CL_4052041 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010062)))
SubClassOf(obo:CL_4052041 obo:CL_0002491)

# Class: obo:CL_4052042 (tuft cell of urethra)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30379593") Annotation(oboInOwl:hasDbXref "PMID:36993541") Annotation(oboInOwl:hasDbXref "PMID:38548667") obo:IAO_0000115 obo:CL_4052042 "A tuft cell that is part of the epithelium of the urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it stimulates sensory nerve fibres and triggers detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying.")
AnnotationAssertion(terms:contributor obo:CL_4052042 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052042 "2025-02-12T14:39:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38548667") oboInOwl:hasExactSynonym obo:CL_4052042 "urethral brush cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38548667") oboInOwl:hasExactSynonym obo:CL_4052042 "urethral cholinergic chemosensory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38548667") oboInOwl:hasExactSynonym obo:CL_4052042 "urethral tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27680547") rdfs:comment obo:CL_4052042 "Urethral tuft cells are heterogeneous, with both cholinergic and non-cholinergic populations present.")
AnnotationAssertion(rdfs:label obo:CL_4052042 "tuft cell of urethra")
EquivalentClasses(obo:CL_4052042 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002325)))
SubClassOf(obo:CL_4052042 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_1904320))

# Class: obo:CL_4052045 (steroidogenic stromal cell of ovary)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2024.12.15.628550") obo:IAO_0000115 obo:CL_4052045 "A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones.")
AnnotationAssertion(terms:contributor obo:CL_4052045 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052045 "2025-03-05T13:37:44Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasBroadSynonym obo:CL_4052045 "steroidogenic interstitial stromal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasBroadSynonym obo:CL_4052045 "steroidogenic stromal cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasRelatedSynonym obo:CL_4052045 "Enpp2− interstitial cell")
AnnotationAssertion(rdfs:label obo:CL_4052045 "steroidogenic stromal cell of ovary")
EquivalentClasses(obo:CL_4052045 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006960) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0120178)))

# Class: obo:CL_4052046 (early luteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2024.12.15.628550") obo:IAO_0000115 obo:CL_4052046 "A luteal cell that is part of the young, developing corpus luteum. This cell promotes progesterone synthesis, marked by high Parm1 expression in mice (Lan et al., 2024). An early luteal cell is associated with steroidogenesis and cell growth, contributing to early corpus luteum function and maturation.")
AnnotationAssertion(terms:contributor obo:CL_4052046 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052046 "2025-03-05T16:40:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasExactSynonym obo:CL_4052046 "active corpus luteum cell")
AnnotationAssertion(rdfs:label obo:CL_4052046 "early luteal cell")
SubClassOf(obo:CL_4052046 obo:CL_0000175)
SubClassOf(obo:CL_4052046 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006701))

# Class: obo:CL_4052047 (late luteal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31803139") Annotation(oboInOwl:hasDbXref "PMID:36205477") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2024.12.15.628550") obo:IAO_0000115 obo:CL_4052047 "A luteal cell that is part of the older, regressing corpus luteum. This cell exhibits increased expression of genes involved in progesterone metabolism - Akr1c18 in mice (Lan et al., 2024), cell cycle arrest, and apoptosis. A late luteal cell contributes to corpus luteum regression and eventual clearance from the ovary through luteolysis.")
AnnotationAssertion(terms:contributor obo:CL_4052047 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052047 "2025-03-05T16:47:20Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36205477") oboInOwl:hasExactSynonym obo:CL_4052047 "regressing corpus luteum cell")
AnnotationAssertion(rdfs:label obo:CL_4052047 "late luteal cell")
SubClassOf(obo:CL_4052047 obo:CL_0000175)
SubClassOf(obo:CL_4052047 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006709))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
AnnotationAssertion(terms:contributor obo:CL_4052048 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:contributor obo:CL_4052048 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052048 "2024-09-11T09:55:55Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37724716") oboInOwl:hasBroadSynonym obo:CL_4052048 "intercalated duct cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37724716") oboInOwl:hasExactSynonym obo:CL_4052048 "salivary intercalated duct cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35799078") oboInOwl:hasRelatedSynonym obo:CL_4052048 "Id cell")
AnnotationAssertion(rdfs:label obo:CL_4052048 "intercalated cell of salivary gland")
SubClassOf(obo:CL_4052048 obo:CL_1001596)
SubClassOf(obo:CL_4052048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014727))
SubClassOf(obo:CL_4052048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015766))

# Class: obo:CL_4052049 (striated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:34147989") Annotation(oboInOwl:hasDbXref "PMID:36726292") obo:IAO_0000115 obo:CL_4052049 "An columnar/cuboidal epithelial cell that is part of the striated duct of salivary gland, characterized by basal striations formed by infoldings of the plasma membrane. This cell play a crucial role in modifying the electrolyte composition and concentration of saliva through active ion transport, particularly the absorption of sodium and secretion of potassium.")
AnnotationAssertion(terms:contributor obo:CL_4052049 <https://orcid.org/0000-0003-4389-9821>)
AnnotationAssertion(terms:contributor obo:CL_4052049 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052049 "2024-09-11T10:00:25Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11590591") oboInOwl:hasBroadSynonym obo:CL_4052049 "SD cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11590591") oboInOwl:hasBroadSynonym obo:CL_4052049 "striated duct cells")
AnnotationAssertion(rdfs:label obo:CL_4052049 "striated cell of salivary gland")
EquivalentClasses(obo:CL_4052049 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014729)))
SubClassOf(obo:CL_4052049 obo:CL_1001596)
SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015766))
SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036376))
SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_1990573))

# Class: obo:CL_4052050 (luminal epithelial cell of endometrium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36273006") obo:IAO_0000115 obo:CL_4052050 "An epithelial cell that is part of an endometrium luminal epithelium.")
AnnotationAssertion(terms:contributor obo:CL_4052050 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052050 "2025-03-13T13:46:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31317179") oboInOwl:hasExactSynonym obo:CL_4052050 "endometrial luminal epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052050 "luminal epithelial cell of endometrium")
EquivalentClasses(obo:CL_4052050 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011949)))

# Class: obo:CL_4052051 (uterine natural killer cell 1, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") Annotation(oboInOwl:hasDbXref "PMID:34512661") Annotation(oboInOwl:hasDbXref "PMID:34857954") Annotation(oboInOwl:hasDbXref "PMID:35784314") Annotation(oboInOwl:hasDbXref "PMID:39198675") obo:IAO_0000115 obo:CL_4052051 "​​A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018). It expresses the uterine resident marker CD49a and is distinguished from uNK2 and uNK3 by CD39 expression and the absence of CD103 (Whettlock et al., 2022) and CD160 (Marečková et al., 2024). It also expresses higher levels of killer-cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor B1 (LILRB1), which facilitate interaction with human leukocyte antigens (HLAs) on extravillous trophoblast cells, promoting immune tolerance and implantation. Enriched in the endometrium post-ovulation (Marečková et al., 2024) and prominent in early pregnancy (Whettlock et al., 2022), uNK1 regulates trophoblast invasion and spiral artery remodeling (Zhang & Wei, 2021).")
AnnotationAssertion(terms:contributor obo:CL_4052051 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052051 "2025-03-14T10:48:38Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") oboInOwl:hasNarrowSynonym obo:CL_4052051 "decidual natural killer cell 1")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052051 "uNK1")
AnnotationAssertion(rdfs:label obo:CL_4052051 "uterine natural killer cell 1, human")
EquivalentClasses(obo:CL_4052051 ObjectIntersectionOf(obo:CL_4052028 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_O95971) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_P38570) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P49961) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P56199) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_4052052 (uterine natural killer cell 2, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") Annotation(oboInOwl:hasDbXref "PMID:34857954") Annotation(oboInOwl:hasDbXref "PMID:35784314") Annotation(oboInOwl:hasDbXref "PMID:39198675") obo:IAO_0000115 obo:CL_4052052 "A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), peaking in the first trimester. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK3 by the absence of CD39, CD103 (Whettlock et al., 2022), and CD160 (Marečková et al., 2024), with ITGB2 serving as a defining marker (Vento-Tormo et al., 2018). Functionally, it produces more cytokines upon stimulation than uNK1, suggesting a role in immune defense, and secretes XCL1 chemokines, facilitating interactions with maternal dendritic cells and fetal extravillous trophoblasts (Vento-Tormo et al., 2018).")
AnnotationAssertion(terms:contributor obo:CL_4052052 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052052 "2025-03-14T14:31:03Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") oboInOwl:hasNarrowSynonym obo:CL_4052052 "decidual natural killer cell 2")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052052 "uNK2")
AnnotationAssertion(rdfs:label obo:CL_4052052 "uterine natural killer cell 2, human")
EquivalentClasses(obo:CL_4052052 ObjectIntersectionOf(obo:CL_4052028 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_O95971) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_P38570) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_P49961) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P56199) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_4052053 (uterine natural killer cell 3, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") Annotation(oboInOwl:hasDbXref "PMID:31959757") Annotation(oboInOwl:hasDbXref "PMID:34857954") Annotation(oboInOwl:hasDbXref "PMID:35784314") Annotation(oboInOwl:hasDbXref "PMID:39198675") obo:IAO_0000115 obo:CL_4052053 "A uterine natural killer subset found in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), becoming the dominant uNK subset late in pregnancy. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK2 by CD160 (Marečková et al., 2024) and CD103 expression, the absence of CD39, and low KIR levels (Whettlock et al., 2022). Resembling intraepithelial ILC1 cells, uNK3 primarily supports uterine immune defense (Huhn et al., 2020) and indirectly influences trophoblast behavior through chemokine secretion, such as CCL5 (Vento-Tormo et al., 2018).")
AnnotationAssertion(terms:contributor obo:CL_4052053 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052053 "2025-03-14T16:15:39Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30429548") oboInOwl:hasNarrowSynonym obo:CL_4052053 "decidual natural killer cell 3")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052053 "uNK3")
AnnotationAssertion(rdfs:label obo:CL_4052053 "uterine natural killer cell 3, human")
EquivalentClasses(obo:CL_4052053 ObjectIntersectionOf(obo:CL_4052028 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_P49961) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_O95971) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P38570) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P56199) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_4052055 (mature NK T cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30714682") Annotation(oboInOwl:hasDbXref "PMID:30875134") obo:IAO_0000115 obo:CL_4052055 "A mature NK T cell that can be identified by the expression of CD56 in humans.")
AnnotationAssertion(terms:contributor obo:CL_4052055 <https://orcid.org/0000-0001-5742-4697>)
AnnotationAssertion(terms:contributor obo:CL_4052055 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052055 "2025-03-26T11:56:38Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature NK T lymphocyte, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature NK T-cell, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature NK T-lymphocyte, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature NKT cell, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature natural killer T cell, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature natural killer T lymphocyte, human")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0009-0000-8480-9277") oboInOwl:hasExactSynonym obo:CL_4052055 "mature natural killer T-lymphocyte, human")
AnnotationAssertion(rdfs:label obo:CL_4052055 "mature NK T cell, human")
EquivalentClasses(obo:CL_4052055 ObjectIntersectionOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_P13591) ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))

# Class: obo:CL_4052058 (Merkel cell of epidermis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19834574") Annotation(oboInOwl:hasDbXref "PMID:2274847") Annotation(oboInOwl:hasDbXref "PMID:30415995") Annotation(oboInOwl:hasDbXref "Wikipedia:Merkel_cell") obo:IAO_0000115 obo:CL_4052058 "A Merkel cell found mainly in the basal layer of the epidermis and the outer root sheath of hair follicles, particularly concentrated in areas with high tactile acuity, such as touch domes, hair follicles, and fingertips.")
AnnotationAssertion(terms:contributor obo:CL_4052058 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052058 "2025-06-11T10:01:40Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6207057") oboInOwl:hasExactSynonym obo:CL_4052058 "epdiermal Merkel cell")
AnnotationAssertion(rdfs:label obo:CL_4052058 "Merkel cell of epidermis")
EquivalentClasses(obo:CL_4052058 ObjectIntersectionOf(obo:CL_0000242 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003)))

# Class: obo:CL_4052060 (spinous cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34283481") Annotation(oboInOwl:hasDbXref "wikipedia:Spinous_cell") obo:IAO_0000115 obo:CL_4052060 "A differentiating keratinocyte found in the epidermis and oral epithelium, located in the stratum spinosum, characterized by a spiny appearance due to abundant intercellular desmosomal junctions.")
AnnotationAssertion(terms:contributor obo:CL_4052060 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052060 "2025-07-02T12:21:06Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "wikipedia:Spinous_cell") oboInOwl:hasExactSynonym obo:CL_4052060 "prickle cell")
AnnotationAssertion(rdfs:label obo:CL_4052060 "spinous cell")
SubClassOf(obo:CL_4052060 obo:CL_0000312)
SubClassOf(obo:CL_4052060 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030057))
SubClassOf(obo:CL_4052060 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001365))

# Class: obo:CL_4052061 (epidermal keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D015603") Annotation(oboInOwl:hasDbXref "PMID:15749908") Annotation(oboInOwl:hasDbXref "PMID:19727116") Annotation(oboInOwl:hasDbXref "PMID:38473275") Annotation(oboInOwl:hasDbXref "PMID:39115524") Annotation(oboInOwl:hasDbXref "wikipedia:Keratinocyte") obo:IAO_0000115 obo:CL_4052061 "A keratinocyte of the skin epidermis that synthesizes keratin and undergoes successive stages of differentiation as it migrates from the basal layer to the cornified (stratum corneum) layer. These differentiation stages include the basal, spinous (prickle), and granular cell layers. This cell is central to epidermal homeostasis, mediating wound healing, immune modulation, including the secretion of cytokines and chemokines that recruit neutrophils (Simmons and Gallo, 2024), and intercellular communication with adjacent melanocytes (Marrapodi and Bellei, 2024).")
AnnotationAssertion(terms:contributor obo:CL_4052061 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052061 "2025-07-02T12:32:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052061 "keratincyte of epidermis")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39185948") oboInOwl:hasExactSynonym obo:CL_4052061 "skin keratinocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15749908") Annotation(oboInOwl:hasDbXref "PMID:19727116") rdfs:comment obo:CL_4052061 "Keratinocytes are reportedly CDw210a(IL-10RA)-negative , CDw210b(IL-10RB)-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive.")
AnnotationAssertion(rdfs:label obo:CL_4052061 "epidermal keratinocyte")
EquivalentClasses(obo:CL_4052061 ObjectIntersectionOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003)))
SubClassOf(obo:CL_4052061 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0090023))

# Class: obo:CL_4052062 (onychofibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34099859") Annotation(oboInOwl:hasDbXref "PMID:35853486") Annotation(oboInOwl:hasDbXref "PMID:39044464") obo:IAO_0000115 obo:CL_4052062 "A specialized fibroblast located in the onychodermis that play a key role in nail growth and regeneration by interacting with LGR6-positive nail matrix keratinocytes. These interactions mediate essential signaling pathways, particularly WNT signaling, which is critical for epithelial–mesenchymal communication and coordinated nail development. In humans, this cell expresses key markers, including RSPO4, MSX1, WIF1, and BMP5, all involved in nail differentiation.")
AnnotationAssertion(terms:contributor obo:CL_4052062 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052062 "2025-07-22T14:35:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052062 "onychofibroblast")
SubClassOf(obo:CL_4052062 obo:CL_0000057)
SubClassOf(obo:CL_4052062 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001705))

# Class: obo:CL_4052063 (nail bed keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10651700") Annotation(oboInOwl:hasDbXref "PMID:30969555") Annotation(oboInOwl:hasDbXref "PMID:33799809") Annotation(oboInOwl:hasDbXref "PMID:34099859") Annotation(oboInOwl:hasDbXref "PMID:39044464") obo:IAO_0000115 obo:CL_4052063 "A keratinocyte that resides in the nail bed, responsible for tightly attaching the nail plate to the underlying dermis. Unlike typical epidermal keratinocytes, it exhibits limited proliferation, undergoes modified differentiation that skips the granular layer and conventional cornification, and primarily ensures adhesion and maintenance of the nail plate. In humans, this cell expresses characteristic markers, including the protease inhibitor SPINK6 and the differentiation-associated protein KRT16.")
AnnotationAssertion(terms:contributor obo:CL_4052063 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052063 "2024-07-22T15:30:00Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052063 "nail bed keratinocyte")
SubClassOf(obo:CL_4052063 obo:CL_0000312)
SubClassOf(obo:CL_4052063 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005273))

# Class: obo:CL_4052064 (nail matrix keratinocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28098391") Annotation(oboInOwl:hasDbXref "PMID:30969555") Annotation(oboInOwl:hasDbXref "PMID:34099859") Annotation(oboInOwl:hasDbXref "PMID:39044464") Annotation(oboInOwl:hasDbXref "PMID:7679137") obo:IAO_0000115 obo:CL_4052064 "A keratinocyte that is part of the nail matrix epithelium, distinguished by its high proliferative capacity and its role in nail plate formation via onychokeratinization, a differentiation process that uniquely bypasses the formation of a granular layer, resulting in the production of hard, compact keratin. Unlike skin epidermal keratinocytes, this cell expresses a distinctive mix of hard (hair-type) and select epidermal keratins (Kitahara and Ogawa, 1993). In humans, LGR6 and WNT6 are enriched in the basal compartment, with LGR6 marking nail stem cells in both mice and humans, and exhibiting strong expression in the human proximal nail matrix (Kim et al., 2021).")
AnnotationAssertion(terms:contributor obo:CL_4052064 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052064 "2025-07-22T15:30:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39044464") oboInOwl:hasExactSynonym obo:CL_4052064 "nail matrix epithelial keratinocyte")
AnnotationAssertion(rdfs:label obo:CL_4052064 "nail matrix keratinocyte")
EquivalentClasses(obo:CL_4052064 ObjectIntersectionOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002283)))

# Class: obo:CL_4052065 (serous acinar cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29383862") Annotation(oboInOwl:hasDbXref "PMID:32829674") Annotation(oboInOwl:hasDbXref "PMID:35343828") obo:IAO_0000115 obo:CL_4052065 "An acinar cell of the salivary gland, characterized by a pyramidal or triangular shape with a spherical nucleus and abundant eosinophilic zymogen granules. This cell secretes watery, enzyme‐rich fluid containing α-amylase, proline-rich proteins, and secretory immunoglobulins for starch digestion and antimicrobial defence. In humans and mice, serous acinar cell predominates in the parotid gland and to a lesser extent in the submandibular gland, where it exists alongside mucous acinar cells (Maruyama et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4052065 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052065 "2025-08-05T15:24:46Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052065 "serous acinar cell of salivary gland")
EquivalentClasses(obo:CL_4052065 ObjectIntersectionOf(obo:CL_0000313 obo:CL_0002623 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013232)))
SubClassOf(obo:CL_4052065 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042588))
SubClassOf(obo:CL_4052065 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005983))

# Class: obo:CL_4052066 (mucous acinar cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29383862") Annotation(oboInOwl:hasDbXref "PMID:32829674") Annotation(oboInOwl:hasDbXref "PMID:35343828") obo:IAO_0000115 obo:CL_4052066 "An acinar cell of the salivary gland, responsible for producing a viscous, mucin‐rich solution, thereby facilitating lubrication and protection of the oral mucosa. This cell is characterized by an elongated shape, clear cytoplasm filled with mucin granules, and a basally compressed nucleus (Barrows et al., 2020). In humans and mice, the mucous acinar cell predominates in the sublingual gland and minor salivary glands, while also being present in mixed glands such as the submandibular gland, where it coexists with serous acinar cells (Maruyama et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4052066 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052066 "2025-08-05T15:33:46Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052066 "mucous acinar cell of salivary gland")
EquivalentClasses(obo:CL_4052066 ObjectIntersectionOf(obo:CL_0002623 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014717)))
SubClassOf(obo:CL_4052066 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0098594))
SubClassOf(obo:CL_4052066 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_4052067 (seromucous acinar cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29383862") Annotation(oboInOwl:hasDbXref "PMID:35343828") Annotation(oboInOwl:hasDbXref "PMID:36726292") obo:IAO_0000115 obo:CL_4052067 "An acinar cell of the salivary gland, with a hybrid seromucous phenotype, co-expressing serous and mucous markers and producing a mixed secretion of enzymes-containing serous fluid and mucins essential for lubrication, digestion, and antimicrobial defense. Predominant in the submandibular glands of humans and mice, its differentiation and secretory gene expression are regulated by FGFR2b–MAPK signaling, driven by paracrine FGF7 from adjacent myoepithelial cells, which provides a key niche signal for seromucous identity.")
AnnotationAssertion(terms:contributor obo:CL_4052067 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052067 "2025-08-06T11:26:37Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052067 "seromucous acinar cell of salivary gland")
SubClassOf(obo:CL_4052067 obo:CL_0000159)
SubClassOf(obo:CL_4052067 obo:CL_0002623)

# Class: obo:CL_4052069 (excretory duct cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28192873") Annotation(oboInOwl:hasDbXref "PMID:31194408") Annotation(oboInOwl:hasDbXref "doi:/10.1007/978-3-030-35784-9_2") Annotation(oboInOwl:hasDbXref "doi:10.5772/intechopen.75538") obo:IAO_0000115 obo:CL_4052069 "A duct epithelial cell that is part of the excretory duct of the salivary gland, which transports saliva from the intralobular ductal system to the oral cavity. While primarily serving as a conduit, this cell may play a role in the saliva modification, contributing to its hypotonicity. In humans, this cell has a pseudostratified columnar shape.")
AnnotationAssertion(terms:contributor obo:CL_4052069 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052069 "2025-08-08T11:20:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1007/978-3-030-35784-9_2") oboInOwl:hasExactSynonym obo:CL_4052069 "salivary excretory duct cell")
AnnotationAssertion(rdfs:label obo:CL_4052069 "excretory duct cell of salivary gland")
SubClassOf(obo:CL_4052069 obo:CL_1001596)
SubClassOf(obo:CL_4052069 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0035049))

# Class: obo:CL_4052070 (dual-feature fallopian tube progenitor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:40475517") obo:IAO_0000115 obo:CL_4052070 "A bipotent progenitor cell within the human fallopian tube epithelium, characterized by the concurrent expression of epithelial (e.g., EpCAM/CD326) and endothelial (e.g., PECAM1/CD31) markers at both the cell surface and transcript levels. This cell has the capacity to differentiate into ciliated and secretory epithelial cells, as well as potentially endothelial/stromal lineages. Positioned at the apex of lineage bifurcation, the cell exhibits stem-like and endothelial features, representing an intermediate developmental state between undifferentiated progenitors and lineage-committed epithelial cells.")
AnnotationAssertion(terms:contributor obo:CL_4052070 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052070 "2025-08-12T16:05:47Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:40475517") oboInOwl:hasExactSynonym obo:CL_4052070 "unclassified fallopian tube progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35320732") oboInOwl:hasNarrowSynonym obo:CL_4052070 "non-ciliated secretory epithelial cell 2-1 (NCSE2-1 cells)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35320732") oboInOwl:hasNarrowSynonym obo:CL_4052070 "non-ciliated secretory epithelial cell 2-2 (NCSE2-2 cells)")
AnnotationAssertion(rdfs:label obo:CL_4052070 "dual-feature fallopian tube progenitor cell")
SubClassOf(obo:CL_4052070 obo:CL_0011026)
SubClassOf(obo:CL_4052070 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600124))
SubClassOf(obo:CL_4052070 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4052071 (quiescent fibroblast)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21049082") Annotation(oboInOwl:hasDbXref "PMID:35701396") Annotation(oboInOwl:hasDbXref "PMID:40538750") Annotation(oboInOwl:hasDbXref "Wikipedia:Fibroblast") Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41427-020-0226-7") obo:IAO_0000115 obo:CL_4052071 "A fibroblast in a quiescent state, characterized by a smaller, spindle-shaped morphology with a relatively small cytoplasm, modest rough endoplasmic reticulum and condensed chromatin. Despite low proliferation and contractility, it maintains high metabolic activity for extracellular-matrix homeostasis through continuous matrix protein turnover and mechanosensitive signaling. This cell can rapidly differentiate into contractile myofibroblasts under injury or inflammatory cues to drive tissue repair.")
AnnotationAssertion(terms:contributor obo:CL_4052071 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052071 "2025-08-13T15:42:37Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22529592") oboInOwl:hasExactSynonym obo:CL_4052071 "inactive fibroblast")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID: 35701396") rdfs:comment obo:CL_4052071 "Historically, quiescent fibroblasts in uninjured tissues were often called “fibrocytes”, but this distinction faded over time, and the term “fibroblast” came to be used universally, regardless of activation state. Fibrocyte has been repurposed to describe a distinct population of bone marrow–derived, circulating cells that home to sites of injury and contribute to tissue repair and fibrosis.")
AnnotationAssertion(rdfs:label obo:CL_4052071 "quiescent fibroblast")
SubClassOf(obo:CL_4052071 obo:CL_0000057)

# Class: obo:CL_4052108 (IgD-negative class switched memory B cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20839340") Annotation(oboInOwl:hasDbXref "PMID:32741082") Annotation(oboInOwl:hasDbXref "PMID:36617261") Annotation(oboInOwl:hasDbXref "PMID:37254600") obo:IAO_0000115 obo:CL_4052108 "A class switched memory B cell that lacks IgD on the cell surface.")
AnnotationAssertion(terms:contributor obo:CL_4052108 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052108 "2025-12-08T10:33:49Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4052108 "IgD-negative class switched memory B cell")
EquivalentClasses(obo:CL_4052108 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738)))

# Class: obo:CL_4070010 (gastric mill neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070010 "A motor neuron that moves the medial tooth forward")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070010 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070010 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070010 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070010 "GM")
AnnotationAssertion(rdfs:label obo:CL_4070010 "gastric mill neuron")
SubClassOf(obo:CL_4070010 obo:CL_0000100)
SubClassOf(obo:CL_4070010 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070010 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070011 (lateral gastric neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070011 "A motor neuron that closes the lateral teeth.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070011 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070011 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070011 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070011 "LG")
AnnotationAssertion(rdfs:label obo:CL_4070011 "lateral gastric neuron")
SubClassOf(obo:CL_4070011 obo:CL_0000100)
SubClassOf(obo:CL_4070011 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070011 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070012 (inferior cardiac neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070012 "A motor neuron that controls ventral stomach grooves leading to pyloric filter.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070012 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070012 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070012 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070012 "IC")
AnnotationAssertion(rdfs:label obo:CL_4070012 "inferior cardiac neuron")
SubClassOf(obo:CL_4070012 obo:CL_0000100)
SubClassOf(obo:CL_4070012 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070012 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070013 (ventricular dilator motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070013 "A motor neuron that controls  ventral stomach grooves leading to pyloric filter.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070013 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070013 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070013 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070013 "VD")
AnnotationAssertion(rdfs:label obo:CL_4070013 "ventricular dilator motor neuron")
SubClassOf(obo:CL_4070013 obo:CL_0000100)
SubClassOf(obo:CL_4070013 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070013 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070014 (pyloric motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6296329") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070014 "A motor neuron that controls pyloric filter movements; innervates the pyloric muscle.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070014 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070014 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070014 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070014 "PY")
AnnotationAssertion(rdfs:label obo:CL_4070014 "pyloric motor neuron")
SubClassOf(obo:CL_4070014 obo:CL_0000100)
SubClassOf(obo:CL_4070014 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070014 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070015 (pyloric dilator neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6296329") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070015 "A motor neuron that controls the cardiopyloric valve.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070015 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070015 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070015 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070015 "PD")
AnnotationAssertion(rdfs:label obo:CL_4070015 "pyloric dilator neuron")
SubClassOf(obo:CL_4070015 obo:CL_0000100)
SubClassOf(obo:CL_4070015 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070015 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070016 (anterior burster neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6296329") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070016 "Pyloric pacemaker neuron that provides feedback to commissural ganglia (CoG) neurons.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070016 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070016 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070016 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070016 "AB")
AnnotationAssertion(rdfs:label obo:CL_4070016 "anterior burster neuron")
SubClassOf(obo:CL_4070016 obo:CL_0000099)
SubClassOf(obo:CL_4070016 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070016 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4070017 (lateral pyloric motor neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:6296329") Annotation(oboInOwl:hasDbXref "doi:10.1007/978-3-642-71516-7_2") obo:IAO_0000115 obo:CL_4070017 "A motor neuron that controls pyloric filter movements; innervates the lateral pyloric muscle.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4070017 obo:NCBITaxon_6712)
AnnotationAssertion(obo:RO_0002175 obo:CL_4070017 obo:NCBITaxon_6752)
AnnotationAssertion(terms:contributor obo:CL_4070017 <https://orcid.org/0000-0002-1909-7004>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4070017 "LP")
AnnotationAssertion(rdfs:label obo:CL_4070017 "lateral pyloric motor neuron")
SubClassOf(obo:CL_4070017 obo:CL_0000100)
SubClassOf(obo:CL_4070017 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_8910001))
SubClassOf(obo:CL_4070017 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_6657))

# Class: obo:CL_4072001 (newly formed oligodendrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasDbXref "PMID:39233334") obo:IAO_0000115 obo:CL_4072001 "A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state.")
AnnotationAssertion(terms:contributor obo:CL_4072001 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072001 "NFOL")
AnnotationAssertion(rdfs:label obo:CL_4072001 "newly formed oligodendrocyte"@en)
SubClassOf(obo:CL_4072001 obo:CL_0000123)
SubClassOf(obo:CL_4072001 obo:CL_0000128)
SubClassOf(obo:CL_4072001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_4072001 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4023059))

# Class: obo:CL_4072002 (myelin-forming oligodendrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasDbXref "PMID:30837646") Annotation(oboInOwl:hasDbXref "PMID:39233334") Annotation(oboInOwl:hasDbXref "PMID:9473608") obo:IAO_0000115 obo:CL_4072002 "A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production.")
AnnotationAssertion(terms:contributor obo:CL_4072002 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39233334") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072002 "MFOL")
AnnotationAssertion(rdfs:label obo:CL_4072002 "myelin-forming oligodendrocyte"@en)
SubClassOf(obo:CL_4072002 obo:CL_0000128)
SubClassOf(obo:CL_4072002 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_4072002 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4072001))
SubClassOf(obo:CL_4072002 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032289))

# Class: obo:CL_4072003 (mature myelinating oligodendrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasDbXref "PMID:33203872") obo:IAO_0000115 obo:CL_4072003 "A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance.")
AnnotationAssertion(terms:contributor obo:CL_4072003 <https://orcid.org/0000-0002-5507-2103>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27284195") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072003 "MOL")
AnnotationAssertion(rdfs:label obo:CL_4072003 "mature myelinating oligodendrocyte")
SubClassOf(obo:CL_4072003 obo:CL_0000128)
SubClassOf(obo:CL_4072003 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043209))
SubClassOf(obo:CL_4072003 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4072002))
SubClassOf(obo:CL_4072003 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032289))

# Class: obo:CL_4072005 (A8 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32869307") Annotation(oboInOwl:hasDbXref "PMID:33756109") Annotation(oboInOwl:hasDbXref "PMID:34532720") Annotation(oboInOwl:hasDbXref "PMID:8514911") obo:IAO_0000115 obo:CL_4072005 "A type of midbrain dopaminergic neuron localized in the retrorubral field which projects to limbic and cortical regions involved in emotion, motivation, and reward.")
AnnotationAssertion(terms:date obo:CL_4072005 "2025-05-02T08:37:36Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33756109") oboInOwl:hasExactSynonym obo:CL_4072005 "A8 dopamine neuron")
AnnotationAssertion(rdfs:label obo:CL_4072005 "A8 dopaminergic neuron")
SubClassOf(obo:CL_4072005 obo:CL_2000097)
SubClassOf(obo:CL_4072005 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0011172))
SubClassOf(obo:CL_4072005 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072006 (A9 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23603197") Annotation(oboInOwl:hasDbXref "PMID:24843012") Annotation(oboInOwl:hasDbXref "PMID:26430123") Annotation(oboInOwl:hasDbXref "PMID:32869307") Annotation(oboInOwl:hasDbXref "PMID:38092916") Annotation(oboInOwl:hasDbXref "PMID:39961377") obo:IAO_0000115 obo:CL_4072006 "A type of dopaminergic neuron in the substantia nigra involved in motor control and particularly vulnerable in Parkinson’s disease. In mice, it is notable for its heterogeneous co-release of dopamine with either glutamate or GABA. It releases GABA through alternative synthesis pathways or reuptake mechanisms independent of GAD expression.")
AnnotationAssertion(terms:date obo:CL_4072006 "2025-05-02T09:59:34Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20049900") oboInOwl:hasExactSynonym obo:CL_4072006 "A9 nigral dopamine neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31704946") oboInOwl:hasExactSynonym obo:CL_4072006 "substantia nigra dopaminergic neuron")
AnnotationAssertion(rdfs:label obo:CL_4072006 "A9 dopaminergic neuron")
SubClassOf(obo:CL_4072006 obo:CL_4042025)
SubClassOf(obo:CL_4072006 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002038))
SubClassOf(obo:CL_4072006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))
SubClassOf(obo:CL_4072006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4072006 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061535))

# Class: obo:CL_4072007 (A10 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23603197") Annotation(oboInOwl:hasDbXref "PMID:3107759") Annotation(oboInOwl:hasDbXref "PMID:32869307") obo:IAO_0000115 obo:CL_4072007 "A type of dopaminergic neuron found in the ventral tegmental area that is involved in reward processes, motivation and addiction.")
AnnotationAssertion(terms:date obo:CL_4072007 "2025-05-02T10:13:27Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:3107759") oboInOwl:hasExactSynonym obo:CL_4072007 "A10 VTA Dopaminergic Neuron")
AnnotationAssertion(rdfs:label obo:CL_4072007 "A10 dopaminergic neuron")
SubClassOf(obo:CL_4072007 obo:CL_2000097)
SubClassOf(obo:CL_4072007 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002691))
SubClassOf(obo:CL_4072007 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072008 (A11 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25343491") Annotation(oboInOwl:hasDbXref "PMID:37522391") Annotation(oboInOwl:hasDbXref "PMID:8978475") obo:IAO_0000115 obo:CL_4072008 "A type of hypothalamic dopaminergic neuron found in the posterior hypothalamus, projecting to the spinal cord where it modulates pain, motor activity (Koblinger et al., 2014), and somatosensory processing (Zhang et a., 2023).")
AnnotationAssertion(terms:date obo:CL_4072008 "2025-05-02T10:33:56Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072008 "A11 dopaminergic neuron")
SubClassOf(obo:CL_4072008 obo:CL_0000700)
SubClassOf(obo:CL_4072008 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002770))
SubClassOf(obo:CL_4072008 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072009 (A12 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39919032") obo:IAO_0000115 obo:CL_4072009 "A type of dopaminergic neuron found in the arcuate hypothalamic nucleus, involved in neuroendocrine regulation, metabolic homeostasis and prolactin secretion.")
AnnotationAssertion(terms:date obo:CL_4072009 "2025-05-02T10:43:50Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39919032") oboInOwl:hasExactSynonym obo:CL_4072009 "hypothalamic arcuate nucleus dopaminergic neuron")
AnnotationAssertion(rdfs:label obo:CL_4072009 "A12 dopaminergic neuron")
SubClassOf(obo:CL_4072009 obo:CL_0000700)
SubClassOf(obo:CL_4072009 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001932))
SubClassOf(obo:CL_4072009 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072010 (A13 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33318433") Annotation(oboInOwl:hasDbXref "PMID:37816347") obo:IAO_0000115 obo:CL_4072010 "A type of dopaminergic neuron located in the rostro-medial part of the zona incerta. It is involved in nociception and prehensile movement.")
AnnotationAssertion(terms:date obo:CL_4072010 "2025-05-02T14:46:33Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072010 "A13 dopaminergic neuron")
SubClassOf(obo:CL_4072010 obo:CL_0000700)
SubClassOf(obo:CL_4072010 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0036007))
SubClassOf(obo:CL_4072010 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072011 (A14 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10465451") Annotation(oboInOwl:hasDbXref "PMID:19210380") Annotation(oboInOwl:hasDbXref "PMID:33257725") Annotation(oboInOwl:hasDbXref "PMID:36209152") obo:IAO_0000115 obo:CL_4072011 "A type of dopaminergic neuron located in the periventricular nucleus of the hypothalamus and projecting to the lateral septum and the median eminence. It is contributing to neuroendocrine functions, locomotion and stress regulation.")
AnnotationAssertion(terms:date obo:CL_4072011 "2025-05-06T12:46:22Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072011 "A14 dopaminergic neuron")
SubClassOf(obo:CL_4072011 obo:CL_0000700)
SubClassOf(obo:CL_4072011 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002322))
SubClassOf(obo:CL_4072011 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072012 (A15 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26132331") Annotation(oboInOwl:hasDbXref "PMID:36209152") obo:IAO_0000115 obo:CL_4072012 "A type of dopaminergic neuron located in the preoptic periventricular nucleus of the hypothalamus and implicated in neuroendocrine modulation.")
AnnotationAssertion(terms:date obo:CL_4072012 "2025-05-06T13:00:54Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072012 "A15 dopaminergic neuron")
SubClassOf(obo:CL_4072012 obo:CL_0000700)
SubClassOf(obo:CL_4072012 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002622))
SubClassOf(obo:CL_4072012 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))

# Class: obo:CL_4072013 (A16 dopaminergic neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28261065") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2023.08.29.554772") obo:IAO_0000115 obo:CL_4072013 "A type of dopaminergic interneuron located in the glomerular layer of the main olfactory bulb, characterized by the co-release of dopamine and GABA, and involved in modulating sensory input within olfactory circuits.")
AnnotationAssertion(terms:date obo:CL_4072013 "2025-05-06T13:12:14Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072013 "A16 dopaminergic neuron")
SubClassOf(obo:CL_4072013 obo:CL_0000099)
SubClassOf(obo:CL_4072013 obo:CL_0000700)
SubClassOf(obo:CL_4072013 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0005377))
SubClassOf(obo:CL_4072013 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061527))
SubClassOf(obo:CL_4072013 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_4072014 (tanycyte of vascular organ of lamina terminalis)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") Annotation(oboInOwl:hasDbXref "PMID:26017494") obo:IAO_0000115 obo:CL_4072014 "A specialized, non-ciliated ependymal glial cell located in the ventricular wall of the organum vasculosum of the lamina terminalis (OVLT) and characterized by elongated basal processes extending into the parenchyma to contact fenestrated capillaries. In mice, it is characterised by the expression of tight junction proteins (claudin 1, occludin, ZO-1) forming a continuous honeycomb junctional pattern. This cell contributes to a functional blood–cerebrospinal fluid (CSF) barrier at the ventricular interface of the OVLT.")
AnnotationAssertion(terms:date obo:CL_4072014 "2025-06-04T10:27:59Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23649873") oboInOwl:hasBroadSynonym obo:CL_4072014 "Tanycyte-like cells in CVOs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32071335") oboInOwl:hasExactSynonym obo:CL_4072014 "tanycyte-like cell of OVLT")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32071335") oboInOwl:hasExactSynonym obo:CL_4072014 "tanycyte-like ependymal cell of OVLT")
AnnotationAssertion(rdfs:label obo:CL_4072014 "tanycyte of vascular organ of lamina terminalis")
SubClassOf(obo:CL_4072014 obo:CL_0002085)
SubClassOf(obo:CL_4072014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002689))

# Class: obo:CL_4072015 (monocyte-derived Kupffer cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26813785") Annotation(oboInOwl:hasDbXref "PMID:31561945") Annotation(oboInOwl:hasDbXref "PMID:37740916") obo:IAO_0000115 obo:CL_4072015 "A Kupffer cell located within the hepatic sinusoids, derived from circulating bone marrow monocytes that acquire the phenotypic markers and functional properties of resident Kupffer cells through niche-dependent imprinting, typically following depletion of the embryonically derived Kupffer cell population. During liver injury, MoKCs become the dominant Kupffer cell subset, exhibiting enhanced proliferation, resistance to apoptosis, and key roles in tissue repair and fibrosis attenuation.")
AnnotationAssertion(terms:date obo:CL_4072015 "2025-07-11T00:00:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37740916") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072015 "MoKC")
AnnotationAssertion(rdfs:label obo:CL_4072015 "monocyte-derived Kupffer cell")
SubClassOf(obo:CL_4072015 obo:CL_0000091)
SubClassOf(obo:CL_4072015 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281))
SubClassOf(obo:CL_4072015 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000860))

# Class: obo:CL_4072016 (NPY interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19295167") Annotation(oboInOwl:hasDbXref "PMID:32376782") obo:IAO_0000115 obo:CL_4072016 "An interneuron that expresses neuropeptide Y (NPY) and is mainly located in cortical layers II–III and VI, as well as in various brain regions such as the medial geniculate and inferior colliculus. The NPY cell population is physiologically diverse, displaying a range of firing behaviors, including adapting, fast-spiking, and accelerating patterns.")
AnnotationAssertion(terms:date obo:CL_4072016 "2025-07-07T09:04:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32376782") oboInOwl:hasExactSynonym obo:CL_4072016 "NPY-expressing neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:19295167") oboInOwl:hasRelatedSynonym obo:CL_4072016 "NPY-expressing neocortical interneuron")
AnnotationAssertion(rdfs:label obo:CL_4072016 "NPY interneuron")
SubClassOf(obo:CL_4072016 obo:CL_0000099)
SubClassOf(obo:CL_4072016 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4072016 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000011387))

# Class: obo:CL_4072017 (agouti-related protein expressing neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34469623") Annotation(oboInOwl:hasDbXref "PMID:37957320") Annotation(oboInOwl:hasDbXref "PMID:39719709") obo:IAO_0000115 obo:CL_4072017 "A GABAergic neuron located in the arcuate nucleus of the hypothalamus that expresses agouti-related protein (AgRP). This neuron can coexpress AgRP, GABA, and neuropeptide Y (NPY) in mice, and plays a key role in integrating metabolic signals. It is activated by hunger-related hormones such as ghrelin and inhibited by satiety signals like leptin.")
AnnotationAssertion(terms:date obo:CL_4072017 "2025-07-07T09:55:43Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39719709") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072017 "AgRP neuron")
AnnotationAssertion(rdfs:label obo:CL_4072017 "agouti-related protein expressing neuron")
SubClassOf(obo:CL_4072017 obo:CL_0000617)
SubClassOf(obo:CL_4072017 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001932))
SubClassOf(obo:CL_4072017 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003846))
SubClassOf(obo:CL_4072017 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000011387))

# Class: obo:CL_4072018 (pacemaker neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31982322") Annotation(oboInOwl:hasDbXref "PMID:39303139") obo:IAO_0000115 obo:CL_4072018 "A neuron that generates rhythmic bursts of action potentials independently of synaptic input. This intrinsic property enables it to maintain oscillatory activity even when isolated from other neurons. It populates the brainstem, hypothalamus, basal ganglia, spinal cord, and cerebellum. It plays a crucial role in regulating circadian rhythms in the suprachiasmatic nucleus, generating respiratory rhythms in the preBötzinger complex, and synchronizing neural networks.")
AnnotationAssertion(terms:date obo:CL_4072018 "2025-07-07T12:37:16Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4072018 "pacemaker neuron")
SubClassOf(obo:CL_4072018 obo:CL_0000540)
SubClassOf(obo:CL_4072018 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019226))

# Class: obo:CL_4072019 (SCN pacemaker neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20148688") Annotation(oboInOwl:hasDbXref "PMID:32066983") obo:IAO_0000115 obo:CL_4072019 "A type of neuron located in the suprachiasmatic nucleus (SCN) that possesses intrinsic circadian rhythmicity, characterized by strong and rhythmic expression of core clock genes and the ability to independently generate and sustain circadian oscillations. In mice, the specific subtypes Avp+/Nms+, Vip+/Nms+, and Cck+/C1ql3+ neurons have the most robust circadian gene expression and contribute to synchronizing and maintaining rhythmicity within the SCN network (Wen et al., 2020).")
AnnotationAssertion(terms:date obo:CL_4072019 "2025-07-14T10:10:28Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20148688") oboInOwl:hasExactSynonym obo:CL_4072019 "pacemaker neuron of the suprachiasmatic nucleus")
AnnotationAssertion(rdfs:label obo:CL_4072019 "SCN pacemaker neuron")
SubClassOf(obo:CL_4072019 obo:CL_0000540)
SubClassOf(obo:CL_4072019 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002034))

# Class: obo:CL_4072021 (corticotropin-releasing neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21871477") Annotation(oboInOwl:hasDbXref "PMID:2785663") Annotation(oboInOwl:hasDbXref "PMID:28790896") Annotation(oboInOwl:hasDbXref "PMID:33158870") Annotation(oboInOwl:hasDbXref "PMID:9662138") obo:IAO_0000115 obo:CL_4072021 "A specialised type of interneuron defined by the secretion of corticotropin-releasing hormone (CRH), a key peptide in activating the hypothalamic–pituitary–adrenal (HPA) axis during stress. It is primarily located in the paraventricular nucleus (PVN) of the hypothalamus, with additional presence in the hippocampus, piriform area, central amygdalar nucleus, Barrington’s nucleus, and inferior olivary complex (Peng et al., 2017).")
AnnotationAssertion(terms:date obo:CL_4072021 "2025-07-14T12:17:35Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33158870") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072021 "CRF neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21871477") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072021 "CRH neuron")
AnnotationAssertion(rdfs:label obo:CL_4072021 "corticotropin-releasing neuron")
SubClassOf(obo:CL_4072021 obo:CL_0000099)
SubClassOf(obo:CL_4072021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0051458))

# Class: obo:CL_4072022 (Lamp5 Lhx6 GABAergic interneuron (Homo sapiens))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:36007006") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "PMID:37824669") Annotation(oboInOwl:hasDbXref "PMID:38712198") obo:IAO_0000115 obo:CL_4072022 "A Lamp5 Lhx6 GABAergic interneuron of Homo sapiens. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', Lamp5 Lhx6")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072022 obo:NCBITaxon_9606)
AnnotationAssertion(terms:date obo:CL_4072022 "2025-07-31T14:01:52Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072022 "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32999462") rdfs:comment obo:CL_4072022 "Despite being clustered as CGE in this dataset, other studies suggest that the cell is of MGE origin because it expresses transcription factors such as LHX6 and NKX2-1, which are hallmark indicators of MGE-derived interneurons. Fate mapping experiments in mice have demonstrated that Lamp5+/Lhx6+ interneurons in both the hippocampus and neocortex arise from the MGE, and single-cell transcriptomic comparisons further show that primate neocortical Lamp5+/Lhx6+ cells closely resemble mouse hippocampal MGE-derived interneurons rather than classic CGE-derived types.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://zenodo.org/records/11165918") rdfs:comment obo:CL_4072022 "The marker set CHST9, LAMP5 can identify the Human cell type Lamp5 Lhx6 neuron in the neocortex with a confidence of 0.821678322 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072022 "Lamp5 Lhx6 GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072022 obo:CL_4042013)
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000203))
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000032148))
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000032533))
SubClassOf(obo:CL_4072022 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000075))

# Class: obo:CL_4072027 (sst GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072027 "sst interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:33742131") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4072027 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst). The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Sst.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072027 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072027 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072027 "2025-08-12T10:45:41Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072027 "ILX:0770152")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30001424") oboInOwl:hasRelatedSynonym obo:CL_4072027 "SOM+ inhibitory interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33742131") oboInOwl:hasRelatedSynonym obo:CL_4072027 "SST+ IN (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30001424") oboInOwl:hasRelatedSynonym obo:CL_4072027 "somatostatin-expressing inhibitory interneuron (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072027 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072027 cl:cellxgene_subset)
AnnotationAssertion(rdfs:label obo:CL_4072027 "sst GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072027 obo:CL_4023017)
SubClassOf(obo:CL_4072027 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072027 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000082))

# Class: obo:CL_4072029 (pvalb GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072029 "pvalb interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4072029 "A transcriptomically distinct GABAergic interneuron with a soma located in a cerebral cortex and it expresses Parvalbumin. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Pvalb.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072029 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072029 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072029 "2025-08-12T14:31:10Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072029 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072029 cl:cellxgene_subset)
AnnotationAssertion(rdfs:label obo:CL_4072029 "pvalb GABAergic interneuron (Homo sapiens)")
EquivalentClasses(obo:CL_4072029 ObjectIntersectionOf(obo:CL_4023018 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)))
SubClassOf(obo:CL_4072029 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000080))

# Class: obo:CL_4072031 (sst chodl GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072031 "sst chodl interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15845086") Annotation(oboInOwl:hasDbXref "PMID:31209381") Annotation(oboInOwl:hasDbXref "PMID:33372656") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4072031 "A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sst Chodl.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072031 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072031 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072031 "2025-09-04T10:20:07Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33372656") oboInOwl:hasBroadSynonym obo:CL_4072031 "long-range GABAergic interneuron (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072031 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072031 "The marker set NPY can identify the Human cell type sst chodl GABAergic interneuron in the neocortex with a confidence of 0.894026187 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072031 "sst chodl GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072031 obo:CL_4023121)
SubClassOf(obo:CL_4072031 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072031 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000083))

# Class: obo:CL_4072032 (VIP GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072032 "VIP interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33186530") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4072032 "A transcriptomically distinct GABAergic neuron that expresses the vasoactive intestinal polypeptide and that has its soma located in the forebrain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Vip.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072032 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072032 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072032 "2025-09-04T10:52:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26420784") Annotation(oboInOwl:hasDbXref "PMID:31210267") Annotation(oboInOwl:hasDbXref "PMID:33794534") Annotation(oboInOwl:hasDbXref "PMID:35221922") terms:description obo:CL_4072032 "This neuronal type is distinguished by its heterogeneous morphology and electrophysiological characteristics  (Pronneke et al., 2015,2020; Apicella and Marchionni, 2022). Variations in morphology and firing patterns are observed in human VIP interneurons. In a study by Lee et al., 2023, four distinct subtypes of VIP neurons were identified, each exhibiting unique morphologies, soma locations, and electrophysiological properties. These subtypes are defined according to their transcriptomic markers: LBH-VIP and CCD184-VIP, both of which display a bipolar morphology with axons and dendrites extending across cortical layers; and SY16-VIP and ADAMTSL1-VIP, characterized by a dendritic arbor that spreads horizontally within the same layer as the soma (Lee et al., 2023). Disruption or malfunction of VIP interneuron is implicated in neurodevelopmental disorders such as Rett Syndrome and Dravet Syndrome (Goff and Goldberg 2021).")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072032 "ILX:0770151")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36384143") oboInOwl:hasRelatedSynonym obo:CL_4072032 "VIP neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") oboInOwl:hasRelatedSynonym obo:CL_4072032 "VIP type (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33794534") oboInOwl:hasRelatedSynonym obo:CL_4072032 "VIP-IN (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ILX:0770151") oboInOwl:hasRelatedSynonym obo:CL_4072032 "Vip (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072032 cl:BDS_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072032 "The marker set VIP can identify the Human cell type VIP GABAergic interneuron in the neocortex with a confidence of 0.855531344 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072032 "VIP GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072032 obo:CL_4023016)
SubClassOf(obo:CL_4072032 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_P01282))
SubClassOf(obo:CL_4072032 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000085))

# Class: obo:CL_4072034 (lamp5 GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072034 "Lamp5 interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4072034 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Lamp5.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072034 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072034 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072034 "2025-09-04T14:48:07Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072034 "ILX:0770149")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072034 cl:BDS_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072034 "The marker set LINC00298, KIT can identify the Human cell type lamp5 GABAergic interneuron in the neocortex with a confidence of 0.814687838 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072034 "lamp5 GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072034 obo:CL_4023011)
SubClassOf(obo:CL_4072034 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072034 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000074))

# Class: obo:CL_4072035 (sncg GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072035 "sncg interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33186530") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4072035 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sncg.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072035 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072035 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072035 "2025-09-05T10:49:37Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072035 "ILX:0770150")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072035 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072035 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072035 "The marker set RXRG, THSD7B can identify the Human cell type sncg GABAergic interneuron in the neocortex with a confidence of 0.628943702 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072035 "sncg GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072035 obo:CL_4023015)
SubClassOf(obo:CL_4072035 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072035 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_O76070))
SubClassOf(obo:CL_4072035 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000081))

# Class: obo:CL_4072036 (PAX6 GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072036 "Pax6 interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/e4ddac12-f48f-4455-8e8d-c2a48a683437.cxg/") obo:IAO_0000115 obo:CL_4072036 "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses the transcript PAX6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters PAX")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072036 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072036 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072036 "2025-09-10T08:47:34Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072036 "The marker set RELN, HCRTR2 can identify the Human cell type PAX6 GABAergic interneuron in the neocortex with a confidence of 0.724125093 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072036 "PAX6 GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072036 obo:CL_4042032)
SubClassOf(obo:CL_4072036 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072036 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000079))

# Class: obo:CL_4072037 (L2/3 intratelencephalic projecting glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072037 "L2/3 IT (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25622573") Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4072037 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L2/3 IT.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072037 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072037 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072037 "2025-09-10T09:15:51Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072037 "ILX:0770156")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072037 "L2/3 IT (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072037 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072037 "The marker set ONECUT2, COL5A2 can identify the Human cell type L2/3 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.670149932 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072037 "L2/3 intratelencephalic projecting glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072037 obo:CL_4030059)
SubClassOf(obo:CL_4072037 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072037 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000065))

# Class: obo:CL_4072038 (L5 intratelencephalic projecting glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072038 "L5 IT (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37609206") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4072038 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L5 IT.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072038 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072038 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072038 "2025-09-10T09:47:23Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072038 "ILX:0770157")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072038 "L5 IT (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072038 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072038 "The marker set ARSJ, RORB, KCNK2 can identify the Human cell type L5 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.764261336 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072038 "L5 intratelencephalic projecting glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072038 obo:CL_4030064)
SubClassOf(obo:CL_4072038 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072038 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000068))

# Class: obo:CL_4072039 (L4 intratelencephalic projecting glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072039 "L4 IT (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4072039 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L4 IT.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072039 obo:NCBITaxon_9606)
AnnotationAssertion(terms:date obo:CL_4072039 "2025-09-10T10:05:26Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072039 "L4 IT (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072039 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072039 "The marker set RORB, ST8SIA4 can identify the Human cell type L4 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.720108696 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072039 "L4 intratelencephalic projecting glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072039 obo:CL_4030063)
SubClassOf(obo:CL_4072039 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072039 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000066))

# Class: obo:CL_4072040 (L6 intratelencephalic projecting Car3 glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072040 "L6 IT Car3 (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "doi:10.1007/s00424-024-02923-2") Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.30.518285") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4072040 "A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_cluster', L6 IT Car3.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072040 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072040 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072040 "2025-09-10T10:23:11Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.06.515349") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4072040 "L6 IT Car3 glutamatergic neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.06.515349") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072040 "L6 IT Car3 (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072040 "L6 IT Car3 neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2022.11.30.518285") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072040 "L6-IT-Car3 (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072040 "L6-IT-Car3 cell (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072040 "The marker set SMYD1, THEMIS can identify the Human cell type L6 intratelencephalic projecting Car3 glutamatergic neuron in the neocortex with a confidence of 0.877752028 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072040 "L6 intratelencephalic projecting Car3 glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072040 obo:CL_4030068)
SubClassOf(obo:CL_4072040 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072040 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000072))

# Class: obo:CL_4072041 (L6 intratelencephalic projecting glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072041 "L6 IT (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37609206") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/c3aa4f95-7a18-4a7d-8dd8-ca324d714363.cxg/") obo:IAO_0000115 obo:CL_4072041 "A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted.  The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L6 IT.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072041 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072041 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072041 "2025-09-11T14:38:02Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072041 "ILX:0770158")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072041 "L6 IT (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072041 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072041 "The marker set LINC00507, THEMIS can identify the Human cell type L6 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.641695703 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072041 "L6 intratelencephalic projecting glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072041 obo:CL_4030065)
SubClassOf(obo:CL_4072041 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072041 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000071))

# Class: obo:CL_4072042 (L5/6 near-projecting glutamatergic neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072042 "L5/6 NP (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasDbXref "PMID:37292694") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4072042 "A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6 in humans.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072042 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072042 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072042 "2025-09-16T08:55:09Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34004146") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072042 "L5/6 NP (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072042 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072042 "The marker set NPSR1-AS1, TLL1 can identify the Human cell type L5/6 near-projecting glutamatergic neuron in the neocortex with a confidence of 0.899288218 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072042 "L5/6 near-projecting glutamatergic neuron (Homo sapiens)")
SubClassOf(obo:CL_4072042 obo:CL_4030067)
SubClassOf(obo:CL_4072042 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072042 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000069))

# Class: obo:CL_4072043 (L5 extratelencephalic projecting glutamatergic cortical neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072043 "L5 ET glut (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4072043 "A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons ', Author Categories: 'CrossArea_subclass', clusters L5 ET.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072043 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072043 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072043 "2025-09-16T09:26:37Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.neuron.2005.08.030") oboInOwl:hasBroadSynonym obo:CL_4072043 "subcerebral projection (SCPN) neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31626774") Annotation(rdfs:comment "pyramidal tract-like is used because, unlike pyramidal tract neurons in the motor cortex, neurons in the structures like the auditory cortex do not project to the spinal cord.") oboInOwl:hasExactSynonym obo:CL_4072043 "Pyramidal tract-like (PT-l) (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2011.00001") oboInOwl:hasExactSynonym obo:CL_4072043 "burst-firing layer 5 neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2015.00233") oboInOwl:hasExactSynonym obo:CL_4072043 "thick-tufted layer 5 (TTL5) pyramidal neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/nrn3469") oboInOwl:hasNarrowSynonym obo:CL_4072043 "pyramidal tract (PT) neuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1016/j.neuron.2011.07.029") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072043 "L5b neuron (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072043 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072043 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072043 "The marker set CHST8, POU3F1 can identify the Human cell type L5 extratelencephalic projecting glutamatergic cortical neuron in the neocortex with a confidence of 0.815891473 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072043 "L5 extratelencephalic projecting glutamatergic cortical neuron (Homo sapiens)")
SubClassOf(obo:CL_4072043 obo:CL_4023041)
SubClassOf(obo:CL_4072043 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072043 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000067))

# Class: obo:CL_4072044 (L6 corticothalamic-projecting glutamatergic cortical neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072044 "L6 CT glut (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34616075") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4072044 "A transcriptomically distinct corticothalamic-projecting neuron with a soma found in cortical layer 6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L6 CT.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072044 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072044 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072044 "2025-09-16T09:42:20Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28625486") Annotation(oboInOwl:hasDbXref "PMID:34616075") oboInOwl:hasExactSynonym obo:CL_4072044 "L6 CT (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072044 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072044 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072044 "The marker set SEMA5B, ADAMTSL1, SULF1 can identify the Human cell type L6 corticothalamic-projecting glutamatergic cortical neuron in the neocortex with a confidence of 0.631898455 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072044 "L6 corticothalamic-projecting glutamatergic cortical neuron (Homo sapiens)")
SubClassOf(obo:CL_4072044 obo:CL_4023042)
SubClassOf(obo:CL_4072044 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072044 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000070))

# Class: obo:CL_4072045 (L6b glutamatergic cortical neuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072045 "L6b glut (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.34312") Annotation(oboInOwl:hasDbXref "PMID:30382198") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/d01c9dff-abd1-4825-bf30-2eb2ba74597e.cxg/") obo:IAO_0000115 obo:CL_4072045 "A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neuron', Author Categories: 'CrossArea_subclass', cluster L6b.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072045 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072045 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072045 "2025-09-16T10:30:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072045 "ILX:0770163")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072045 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072045 cl:cellxgene_subset)
AnnotationAssertion(rdfs:label obo:CL_4072045 "L6b glutamatergic cortical neuron (Homo sapiens)")
SubClassOf(obo:CL_4072045 obo:CL_4023038)
SubClassOf(obo:CL_4072045 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4072046 (pvalb chandelier GABAergic interneuron (Homo sapiens))

AnnotationAssertion(obo:IAO_0000028 obo:CL_4072046 "chandelier PV interneuron (Homo sapiens)")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27477017") Annotation(oboInOwl:hasDbXref "PMID:37824655") Annotation(oboInOwl:hasDbXref "https://cellxgene.cziscience.com/e/9c63201d-bfd9-41a8-bbbc-18d947556f3d.cxg/") obo:IAO_0000115 obo:CL_4072046 "A transcriptomically definined GABAergic interneuron of the human pallium.  These cells correspond to the classically defined pvalb chandelier neuron type. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Chandelier.")
AnnotationAssertion(obo:RO_0002175 obo:CL_4072046 obo:NCBITaxon_9606)
AnnotationAssertion(terms:contributor obo:CL_4072046 "https://orcid.org/0000-0002-5507-2103")
AnnotationAssertion(terms:date obo:CL_4072046 "2025-09-29T10:07:47Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4072046 "ILX:0107356")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4072046 "Chandelier PV (Homo sapiens)")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4072046 "chandelier pvalb GABAergic interneuron (Homo sapiens)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072046 cl:BDS_subset)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4072046 cl:cellxgene_subset)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.5281/zenodo.11165918") rdfs:comment obo:CL_4072046 "The marker set GPR149, CA8 can identify the Human cell type chandelier pvalb GABAergic cortical interneuron in the neocortex with a confidence of 0.799748111 (NS-Forest FBeta value).")
AnnotationAssertion(rdfs:label obo:CL_4072046 "pvalb chandelier GABAergic interneuron (Homo sapiens)")
SubClassOf(obo:CL_4072046 obo:CL_4023036)
SubClassOf(obo:CL_4072046 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_4072046 ObjectSomeValuesFrom(obo:RO_0015004 obo:CLM_1000063))

# Class: obo:CL_4072102 (Purkinje layer interneuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35803588") obo:IAO_0000115 obo:CL_4072102 "A type of GABAergic interneuron residing in the Purkinje cell layer of the cerebellar cortex.")
AnnotationAssertion(terms:date obo:CL_4072102 "2025-04-29T13:06:36Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35803588") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072102 "PLI")
AnnotationAssertion(rdfs:label obo:CL_4072102 "Purkinje layer interneuron")
EquivalentClasses(obo:CL_4072102 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002979)))
SubClassOf(obo:CL_4072102 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))

# Class: obo:CL_4072103 (hair follicle dermal stem cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25465495") Annotation(oboInOwl:hasDbXref "PMID:29691589") Annotation(oboInOwl:hasDbXref "PMID:35036581") Annotation(oboInOwl:hasDbXref "PMID:35069694") obo:IAO_0000115 obo:CL_4072103 "A bipotent mesenchymal stem cell that resides in the dermal sheath, specifically within the dermal sheath cup at the base of the hair follicle, characterized by its capacity for self-renewal and differentiation into both dermal sheath and dermal papilla cells throughout hair cycling. In humans, this cell is marked by enriched expression of gremlin-2 (GREM2) and dipeptidase-1 (DPEP1), and acts as a progenitor reservoir sustaining and regenerating the follicle's mesenchymal compartments.")
AnnotationAssertion(terms:contributor obo:CL_4072103 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_4072103 "2025-11-05T11:49:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38016881") oboInOwl:hasNarrowSynonym obo:CL_4072103 "dermal sheath cup cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25465495") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072103 "hfDSC")
AnnotationAssertion(rdfs:label obo:CL_4072103 "hair follicle dermal stem cell")
EquivalentClasses(obo:CL_4072103 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002073)))
SubClassOf(obo:CL_4072103 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042634))

# Class: obo:CL_4072104 (fibrochondrocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28939894") Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasDbXref "PMID:34608249") obo:IAO_0000115 obo:CL_4072104 "A chondrocyte with hybrid fibroblastic-chondrogenic characteristics found in fibrocartilage, particularly in the avascular inner zone and transitional middle zone of the meniscus. In humans, fibrochondrocytes are marked by predominant expression of type I collagen (COL1A1) and fibril-associated collagens (COL3A1, COL6A1), while retaining type II collagen (COL2A1) expression and exhibiting lower SOX9 than hyaline chondrocytes. This molecular profile underlies the synthesis of abundant type I collagen essential for fibrocartilage matrix and reflects an intermediate phenotype between fibroblast and chondrocyte.")
AnnotationAssertion(terms:contributor obo:CL_4072104 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34608249") oboInOwl:hasExactSynonym obo:CL_4072104 "fibrocartilage chondrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28939894") oboInOwl:hasNarrowSynonym obo:CL_4072104 "meniscus fibrochondrocyte")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31871141") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4072104 "FC")
AnnotationAssertion(rdfs:label obo:CL_4072104 "fibrochondrocyte")
EquivalentClasses(obo:CL_4072104 ObjectIntersectionOf(obo:CL_0000138 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001995)))
SubClassOf(obo:CL_4072104 obo:CL_0002320)
SubClassOf(obo:CL_4072104 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0020021))
SubClassOf(obo:CL_4072104 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003264))
SubClassOf(obo:CL_4072104 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003328))
SubClassOf(obo:CL_4072104 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003353))

# Class: obo:CL_7770002 (juxtacanalicular tissue cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25356439") Annotation(oboInOwl:hasDbXref "PMID:32341164") Annotation(oboInOwl:hasDbXref "PMID:39829808") obo:IAO_0000115 obo:CL_7770002 "A trabecular meshwork cell of the juxtacanalicular tissue (JCT), characterized by a spindle-shaped, fibroblast-like morphology within a loose extracellular matrix immediately adjacent to Schlemm's canal. It expresses CHI3L1 (human and mouse) and ANGPTL7 (human), as well as smooth muscle actin for contractility. Unlike other trabecular meshwork cells, it does not form monolayers but exists in a loose network, regulating aqueous humor outflow resistance through continuous ECM remodelling, mechanotransduction, and formation of intracellular pores historically called giant vacuoles.")
AnnotationAssertion(obo:IAO_0000233 obo:CL_7770002 "https://github.com/obophenotype/cell-ontology/issues/3275")
AnnotationAssertion(terms:contributor obo:CL_7770002 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_7770002 "2025-01-29T08:52:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32341164") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_7770002 "JCT cell")
AnnotationAssertion(rdfs:label obo:CL_7770002 "juxtacanalicular tissue cell")
SubClassOf(obo:CL_7770002 obo:CL_0000327)
SubClassOf(obo:CL_7770002 obo:CL_0002367)
SubClassOf(obo:CL_7770002 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))

# Class: obo:CL_7770003 (beam A cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27443500") Annotation(oboInOwl:hasDbXref "PMID:32341164") Annotation(oboInOwl:hasDbXref "PMID:39829808") obo:IAO_0000115 obo:CL_7770003 "A beam cell within the eye's trabecular meshwork, molecularly distinguished by FABP4 expression in humans and spatially intermingled with Beam B cells throughout the uveal and corneoscleral meshwork regions. In mice, a transcriptionally analogous Beam A–like cluster (mC14) exists, sharing core TM markers (Myoc, Mgp, Pdpn, Chil1) and functional attributes.")
AnnotationAssertion(terms:contributor obo:CL_7770003 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_7770003 "2025-08-29T08:53:47Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_7770003 "beam A cell")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:35836364") Annotation(rdfs:comment "Trabecular meshwork (TM) structure. The TM consists of uveal (blue), corneoscleral (red), and juxtacanalicular (green) regions. TM beam cells (blue/red) line the uveal and corneoscleral regions, while JCT cells (green) occupy the juxtacanalicular region.") foaf:depiction obo:CL_7770003 "http://purl.obolibrary.org/obo/cl/images/Trabecular_meshowk_cells_PMID35836364.jpg")
SubClassOf(obo:CL_7770003 obo:CL_7770005)

# Class: obo:CL_7770004 (suprabasal cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17020902") Annotation(oboInOwl:hasDbXref "PMID:30837987") Annotation(oboInOwl:hasDbXref "PMID:32187560") Annotation(oboInOwl:hasDbXref "PMID:32726565") Annotation(oboInOwl:hasDbXref "PMID:37672481") obo:IAO_0000115 obo:CL_7770004 "An epithelial cell that resides in the layer(s) immediately above the basal layer in stratified or pseudostratified epithelia. This cell mainly originates from basal cells and is found across various tissues, including skin, esophagus, oral mucosa, airway, and cornea.")
AnnotationAssertion(terms:contributor obo:CL_7770004 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_7770004 "2025-09-05T07:59:28Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_7770004 "suprabasal cell")
SubClassOf(obo:CL_7770004 obo:CL_0000066)

# Class: obo:CL_7770005 (beam cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25356439") Annotation(oboInOwl:hasDbXref "PMID:27443500") obo:IAO_0000115 obo:CL_7770005 "A trabecular meshwork cell that is part of the eye's trabecular meshwork, residing in the uveal and corneoscleral meshwork regions and serving as the primary biological filter in the aqueous humor drainage cascade. This cell exhibits endothelial-like properties, including production of antithrombogenic substances such as tissue plasminogen activator, while also demonstrating phagocytic activity to remove cellular debris from aqueous humour before the fluid moves deeper into the less porous juxtacanalicular tissue.")
AnnotationAssertion(terms:contributor obo:CL_7770005 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_7770005 "2025-09-12T11:19:45Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_7770005 "beam cell")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:35836364") Annotation(rdfs:comment "Trabecular meshwork (TM) structure. The TM consists of uveal (blue), corneoscleral (red), and juxtacanalicular (green) regions. TM beam cells (blue/red) line the uveal and corneoscleral regions, while JCT cells (green) occupy the juxtacanalicular region.") foaf:depiction obo:CL_7770005 "http://purl.obolibrary.org/obo/cl/images/Trabecular_meshowk_cells_PMID35836364.jpg")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_7770005 obo:CL_0002367)
SubClassOf(obo:CL_7770005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005969))
SubClassOf(obo:CL_7770005 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909))

# Class: obo:CL_7770006 (beam B cell, human)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25356439") Annotation(oboInOwl:hasDbXref "PMID:32341164") Annotation(oboInOwl:hasDbXref "PMID:39829808") obo:IAO_0000115 obo:CL_7770006 "A trabecular meshwork cell within the eye's trabecular meshwork. This cell is molecularly distinguished by TMEFF2 expression in humans. A beam B cell is spatially intermingled with beam A cells throughout the uveal and corneoscleral meshwork regions, but demonstrates a tendency to localise closer to the juxtacanalicular tissue.")
AnnotationAssertion(terms:contributor obo:CL_7770006 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_7770006 "2025-09-15T08:48:01Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_7770006 "beam B cell, human")
AnnotationAssertion(Annotation(dc:license <http://creativecommons.org/licenses/by/4.0/>) Annotation(oboInOwl:hasDbXref "PMID:35836364") Annotation(rdfs:comment "Trabecular meshwork (TM) structure. The TM consists of uveal (blue), corneoscleral (red), and juxtacanalicular (green) regions. TM beam cells (blue/red) line the uveal and corneoscleral regions, while JCT cells (green) occupy the juxtacanalicular region.") foaf:depiction obo:CL_7770006 "http://purl.obolibrary.org/obo/cl/images/Trabecular_meshowk_cells_PMID35836364.jpg")
SubClassOf(obo:CL_7770006 obo:CL_0002367)
SubClassOf(obo:CL_7770006 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))
SubClassOf(obo:CL_7770006 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q9UIK5))

# Class: obo:CP_0000000 (obsolete CP:0000000)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000000 obo:CL_0017500)
AnnotationAssertion(rdfs:comment obo:CP_0000000 "ID was moved to the CL namespace. Use CL:0017500.")
AnnotationAssertion(rdfs:label obo:CP_0000000 "obsolete CP:0000000")
AnnotationAssertion(owl:deprecated obo:CP_0000000 "true"^^xsd:boolean)

# Class: obo:CP_0000025 (obsolete CP:0000025)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000025 obo:CL_0017501)
AnnotationAssertion(rdfs:comment obo:CP_0000025 "ID was moved to the CL namespace. Use CL:0017501.")
AnnotationAssertion(rdfs:label obo:CP_0000025 "obsolete CP:0000025")
AnnotationAssertion(owl:deprecated obo:CP_0000025 "true"^^xsd:boolean)

# Class: obo:CP_0000027 (obsolete CP:0000027)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000027 obo:CL_0017502)
AnnotationAssertion(rdfs:comment obo:CP_0000027 "ID was moved to the CL namespace. Use CL:0017502.")
AnnotationAssertion(rdfs:label obo:CP_0000027 "obsolete CP:0000027")
AnnotationAssertion(owl:deprecated obo:CP_0000027 "true"^^xsd:boolean)

# Class: obo:CP_0000028 (obsolete CP:0000028)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000028 obo:CL_0017503)
AnnotationAssertion(rdfs:comment obo:CP_0000028 "ID was moved to the CL namespace. Use CL:0017503.")
AnnotationAssertion(rdfs:label obo:CP_0000028 "obsolete CP:0000028")
AnnotationAssertion(owl:deprecated obo:CP_0000028 "true"^^xsd:boolean)

# Class: obo:CP_0000035 (obsolete CP:0000035)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000035 obo:CL_0017504)
AnnotationAssertion(rdfs:comment obo:CP_0000035 "ID was moved to the CL namespace. Use CL:0017504.")
AnnotationAssertion(rdfs:label obo:CP_0000035 "obsolete CP:0000035")
AnnotationAssertion(owl:deprecated obo:CP_0000035 "true"^^xsd:boolean)

# Class: obo:CP_0000037 (obsolete CP:0000037)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000037 obo:CL_0017505)
AnnotationAssertion(rdfs:comment obo:CP_0000037 "ID was moved to the CL namespace. Use CL:0017505.")
AnnotationAssertion(rdfs:label obo:CP_0000037 "obsolete CP:0000037")
AnnotationAssertion(owl:deprecated obo:CP_0000037 "true"^^xsd:boolean)

# Class: obo:CP_0000039 (obsolete CP:0000039)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000039 obo:CL_0017506)
AnnotationAssertion(rdfs:comment obo:CP_0000039 "ID was moved to the CL namespace. Use CL:0017506.")
AnnotationAssertion(rdfs:label obo:CP_0000039 "obsolete CP:0000039")
AnnotationAssertion(owl:deprecated obo:CP_0000039 "true"^^xsd:boolean)

# Class: obo:CP_0000040 (obsolete CP:0000040)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000040 obo:CL_0017507)
AnnotationAssertion(rdfs:comment obo:CP_0000040 "ID was moved to the CL namespace. Use CL:0017507.")
AnnotationAssertion(rdfs:label obo:CP_0000040 "obsolete CP:0000040")
AnnotationAssertion(owl:deprecated obo:CP_0000040 "true"^^xsd:boolean)

# Class: obo:CP_0000043 (obsolete CP:0000043)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000043 obo:CL_0017508)
AnnotationAssertion(rdfs:comment obo:CP_0000043 "ID was moved to the CL namespace. Use CL:0017508.")
AnnotationAssertion(rdfs:label obo:CP_0000043 "obsolete CP:0000043")
AnnotationAssertion(owl:deprecated obo:CP_0000043 "true"^^xsd:boolean)

# Class: obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 (obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33)

AnnotationAssertion(obo:IAO_0100001 obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 obo:CL_0017509)
AnnotationAssertion(rdfs:comment obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 "ID was moved to the CL namespace. Use CL:0017509.")
AnnotationAssertion(rdfs:label obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 "obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33")
AnnotationAssertion(owl:deprecated obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 "true"^^xsd:boolean)

# Class: obo:GO_0051932 (synaptic transmission, GABAergic)

EquivalentClasses(obo:GO_0051932 ObjectIntersectionOf(obo:GO_0007268 ObjectSomeValuesFrom(obo:RO_0000057 obo:CHEBI_59888) ObjectSomeValuesFrom(obo:RO_0000057 obo:CL_0000617)))


SubClassOf(ObjectIntersectionOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000160)) obo:CL_0000164)
SubClassOf(ObjectIntersectionOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000945)) obo:CL_0000164)
SubClassOf(ObjectIntersectionOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001264)) obo:CL_0000164)
SubClassOf(Annotation(oboInOwl:hasDbXref <https://github.com/obophenotype/cell-ontology/issues/757>) ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742)) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000031))
)