Planarian Phenotype Ontology is an ontology of phenotypes observed in the planarian Schmidtea mediterranea.
Planarian Phenotype Ontology (PLANP)
https://creativecommons.org/licenses/by/3.0/
editor preferred term
IAO:0000112
uberon
example_of_usage
true
example_of_usage
example of usage
example of usage
has curation status
definition
The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
2012-04-05:
Barry Smith
The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible.
Can you fix to something like:
A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.
Alan Ruttenberg
Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria.
On the specifics of the proposed definition:
We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition.
Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable.
We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
PERSON:Daniel Schober
GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition
definition
editor note
An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
PERSON:Daniel Schober
GROUP:OBI:<http://purl.obfoundry.org/obo/obi>
IAO:0000116
uberon
editor_note
true
editor_note
editor note
editor note
term editor
alternative term
definition source
curator note
An administrative note of use for a curator but of no use for a user
PERSON:Alan Ruttenberg
IAO:0000232
uberon
curator_notes
true
curator_notes
curator note
curator notes
imported from
For external terms/classes, the ontology from which the term was imported
PERSON:Alan Ruttenberg
PERSON:Melanie Courtot
GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
imported from
expand expression to
expand expression to
expand assertion to
OBO foundry unique label
elucidation
term replaced by
An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.
temporal interpretation
https://github.com/oborel/obo-relations/wiki/ROAndTime
tooth SubClassOf 'never in taxon' value 'Aves'
x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.
Chris Mungall
?X DisjointWith RO_0002162 some ?Y
never in taxon
S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T.
https://orcid.org/0000-0002-6601-2165
This relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take ongoing coordinated effort to resolve. Example: metencephalon in teleost
dubious for taxon
defined by inverse
logical macro assertion on an annotation property
relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y
The general property hierarchy is:
"directly P" SubPropertyOf "P"
Transitive(P)
Where we have an annotation assertion
"directly P" "is direct form of" "P"
If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'
Chris Mungall
is direct form of
If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL
is a defining property chain axiom
If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.
is a defining property chain axiom where second argument is reflexive
'anterior end of organism' is-opposite-of 'posterior end of organism'
'increase in temperature' is-opposite-of 'decrease in temperature'
x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).
RO:0002604
quality
is_opposite_of
true
true
is_opposite_of
is opposite of
is_opposite_of
cjm
2018-03-14T00:03:16Z
is positive form of
cjm
2018-03-14T00:03:24Z
is negative form of
part-of is homeomorphic for independent continuants.
R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C.
cjm
2018-10-21T19:46:34Z
R homeomorphic-for C expands to: C SubClassOf R only C. Additionally, for any class D that is disjoint with C, we can also expand to C DisjointWith R some D, D DisjointWith R some C.
is homeomorphic for
An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class.
UBPROP:0000001
uberon
external_definition
true
external_definition
This annotation property may be replaced with an annotation property from an external ontology such as IAO
external_definition
An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class.
Notes on the homology status of this class.
UBPROP:0000003
uberon
homology_notes
true
homology_notes
This annotation property may be replaced with an annotation property from an external ontology such as IAO
homology_notes
Notes on the homology status of this class.
Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'.
UBPROP:0000007
uberon
has_relational_adjective
true
has_relational_adjective
has_relational_adjective
Notes on the how instances of this class vary across species.
UBPROP:0000008
uberon
taxon_notes
true
taxon_notes
taxon_notes
Notes on the how instances of this class vary across species.
Notes on how similar or equivalent classes are represented in other ontologies.
This annotation property may be replaced with an annotation property from an external ontology such as IAO
UBPROP:0000012
uberon
external_ontology_notes
true
external_ontology_notes
external_ontology_notes
Notes on how similar or equivalent classes are represented in other ontologies.
IAO:0100001
synonym typically used in the context of human anatomy
IAO:0100001
synonym typically used in the context of vertebrate anatomy
Term not to be used for direct annotation
Term not to be used for direct manual annotation
AGR slim
Aspergillus GO slim
Candida GO slim
ChEMBL protein targets summary
Drosophila GO slim
FlyBase Drosophila GO ribbon slim
Generic GO slim
Metagenomics GO slim
Mouse GO slim
PIR GO slim
Plant GO slim
Fission yeast GO slim
synapse GO slim
Yeast GO slim
Systematic synonym
Abnormal/normal slim
Absent/present slim
Attribute slim
cell_quality
Disposition slim
Pathology slim
Relational slim: types of quality that require an additional entity in order to exist
Scalar slim
Value slim
eco subset
uberon
dc-contributor
true
dc-contributor
contributor
uberon
dc-creator
true
dc-creator
creator
uberon
dc-source
true
dc-source
derived from resource
subset_property
IAO:0100001
synonym_type_property
consider
has_alternative_id
has_broad_synonym
IAO:0100001
database_cross_reference
IAO:0100001
has_exact_synonym
IAO:0100001
has_narrow_synonym
IAO:0100001
has_obo_format_version
IAO:0100001
has_obo_namespace
IAO:0100001
has_related_synonym
IAO:0100001
has_scope
IAO:0100001
has_synonym_type
in_subset
IAO:0100001
shorthand
uberon
depicted_by
true
depicted_by
depicted by
Sofia Robb
2017-09-11T16:38:22Z
depiction
uberon
foaf-page
true
foaf-page
page
is part of
my brain is part of my body (continuant parthood, two material entities)
my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
this day is part of this year (occurrent parthood)
a core relation that holds between a part and its whole
Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)
A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
part_of
BFO:0000050
external
quality
spatial
uberon
part_of
part_of
part of
part of
part_of
http://www.obofoundry.org/ro/#OBO_REL:part_of
has part
my body has part my brain (continuant parthood, two material entities)
my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
this year has part this day (occurrent parthood)
Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2.
a core relation that holds between a whole and its part
Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)
A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
has_part
BFO:0000051
external
quality
spatial
uberon
has_part
has_part
We use the has_part relation to relate complex qualities to more primitive ones. A complex quality is a collection of qualities. The complex quality cannot exist without the sub-qualities. For example, the quality 'swollen' necessarily comes with the qualities of 'protruding' and 'increased size'.
has part
has part
has_part
Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2.
PATOC:CJM
preceded by
X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)
x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
is preceded by
preceded_by
http://www.obofoundry.org/ro/#OBO_REL:preceded_by
BFO:0000062
is preceded by
takes place after
uberon
preceded_by
preceded_by
preceded by
preceded_by
is preceded by
SIO:000249
takes place after
Allen:precedes
precedes
x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
BFO:0000063
uberon
precedes
precedes
precedes
precedes
occurs in
b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
occurs_in
unfolds in
unfolds_in
BFO:0000066
external
occurs_in
occurs_in
Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant
occurs in
occurs in
site of
[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
BFO:0000067
uberon
contains_process
contains_process
Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant
contains process
contains process
x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
x anterior_to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail: bearer
cjm
2009-07-31T02:15:46Z
BSPO:0000096
rostral_to
spatial
uberon
anterior_to
anterior_to
anterior to
anterior_to
x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
BSPO:cjm
x anterior_to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail: bearer
x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly).
BSPO:0000098
spatial
uberon
dorsal_to
dorsal_to
dorsal to
dorsal_to
x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
BSPO:cjm
x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly).
x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
x posterior_to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail.
BSPO:0000099
caudal to
caudal_to
spatial
uberon
posterior_to
posterior_to
posterior to
posterior_to
x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
BSPO:cjm
x posterior_to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail.
caudal to
x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly).
BSPO:0000102
spatial
uberon
ventral_to
ventral_to
ventral to
ventral_to
x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
BSPO:cjm
x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly).
Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole.
BSPO:0000104
spatial
approximately_perpendicular_to
approximately_perpendicular_to
approximately perpendicular to
Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole.
BSPO:cjm
On the same side as. For example, the left arm is ipsilateral to the left leg.
BSPO:0000105
spatial
ipsilateral_to
ipsilateral_to
ipsilateral to
On the same side as. For example, the left arm is ipsilateral to the left leg.
BSPO:cjm
Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
BSPO:0000107
spatial
uberon
deep_to
deep_to
deep to
deep_to
Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
BSPO:cjm
Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
BSPO:0000108
spatial
uberon
superficial_to
superficial_to
superficial to
superficial_to
Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
BSPO:cjm
Direcly opposite to. i.e. on the opposite side through the axis.
BSPO:0000113
spatial
opposite_to
opposite_to
opposite to
Direcly opposite to. i.e. on the opposite side through the axis.
BSPO:cjm
X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure
BSPO:0000126
spatial
uberon
in_lateral_side_of
in_lateral_side_of
in lateral side of
in_lateral_side_of
https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern
X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
UBERON:cjm
X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure
This relation holds when both the deep_to and ajdacent_to relationship similarly hold.
x immediately deep to y iff x deep_to y and x is contiguous with y.
BSPO:0001107
spatial
uberon
immediately_deep_to
immediately_deep_to
immediately deep to
immediately_deep_to
This relation holds when both the deep_to and ajdacent_to relationship similarly hold.
x immediately deep to y iff x deep_to y and x is contiguous with y.
BSPO:curators
BSPO:0015001
spatial
finishes_axis
finishes_axis
A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. If s finishes axis x, and x has end point p, then x overlaps p
finishes axis
crossing at right angles
BSPO:0015005
spatial
orthogonal_to
orthogonal_to
orthogonal to
crossing at right angles
BSPO:cjm
Intersects at two points.
BSPO:0015006
spatial
passes_through
passes_through
passes through
Intersects at two points.
BSPO:cjm
BSPO:0015007
spatial
starts_axis
starts_axis
A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. . If s starts axis x, and x has start point p, then x overlaps p
starts axis
BSPO:0015008
spatial
surface_of
surface_of
placeholder. used for relation between anatomical surface and an anatomical side.
surface of
x immediately superficial to y iff x superficial to y and x is contiguous with y.
BSPO:0015014
spatial
uberon
immediately_superficial_to
immediately_superficial_to
immediately superficial to
immediately_superficial_to
x immediately superficial to y iff x superficial to y and x is contiguous with y.
BSPO:curators
This document is about information artifacts and their representations
is_about is a (currently) primitive relation that relates an information artifact to an entity.
7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of "mentions" relation. Weaken the is_about relationship to be primitive.
We will try to build it back up by elaborating the various subproperties that are more precisely defined.
Some currently missing phenomena that should be considered "about" are predications - "The only person who knows the answer is sitting beside me" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic.
person:Alan Ruttenberg
Smith, Ceusters, Ruttenberg, 2000 years of philosophy
is about
Restricted to domain
specific_to
specific_to
inheres in
this fragility inheres in this vase
this red color inheres in this apple
a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence
A dependent inheres in its bearer at all times for which the dependent exists.
inheres_in
inheres in
bearer of
this apple is bearer of this red color
this vase is bearer of this fragility
a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence
A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
bearer_of
is bearer of
RO:0000053
uberon
bearer_of
bearer_of
bearer of
bearer of
participates in
this blood clot participates in this blood coagulation
this input material (or this output material) participates in this process
this investigator participates in this investigation
a relation between a continuant and a process, in which the continuant is somehow involved in the process
participates_in
participates in
has participant
this blood coagulation has participant this blood clot
this investigation has participant this investigator
this process has participant this input material (or this output material)
a relation between a process and a continuant, in which the continuant is somehow involved in the process
Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
has_participant
http://www.obofoundry.org/ro/#OBO_REL:has_participant
has participant
this red color is a quality of this apple
a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
A quality inheres in its bearer at all times for which the quality exists.
is quality of
quality_of
quality of
this apple has quality this red color
a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
has_quality
has quality
this cell derives from this parent cell (cell division)
this nucleus derives from this parent nucleus (nuclear division)
a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'.
derives_from
This relation is taken from the RO2005 version of RO. It may be obsoleted and replaced by relations with different definitions. See also the 'develops from' family of relations.
derives from
this parent cell derives into this cell (cell division)
this parent nucleus derives into this nucleus (nuclear division)
a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'.
derives_into
derives into
is location of
my head is the location of my brain
this cage is the location of this rat
a relation between two independent continuants, the location and the target, in which the target is entirely within the location
Most location relations will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
location_of
location of
contained in
Containment is location not involving parthood, and arises only where some immaterial continuant is involved.
Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):
Intended meaning:
domain: material entity
range: spatial region or site (immaterial continuant)
contained_in
contained in
contains
RO:0001019
uberon
contains
contains
contains
contains
located in
my brain is located in my head
this rat is located in this cage
a relation between two independent continuants, the target and the location, in which the target is entirely within the location
Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
Most location relations will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
located_in
http://www.obofoundry.org/ro/#OBO_REL:located_in
located in
This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.
This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.
A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
dos
2017-05-24T09:30:46Z
has regulatory component activity
A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
dos
2017-05-24T09:31:01Z
By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.
has negative regulatory component activity
A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
dos
2017-05-24T09:31:17Z
By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.
has positive regulatory component activity
dos
2017-05-24T09:44:33Z
A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.
has component activity
w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
dos
2017-05-24T09:49:21Z
has component process
A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.
dos
2017-07-19T17:30:36Z
has ligand
dos
2017-09-17T13:52:24Z
Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
directly regulated by
Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
GOC:dos
Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
dos
2017-09-17T13:52:38Z
directly negatively regulated by
Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
GOC:dos
Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
dos
2017-09-17T13:52:47Z
directly positively regulated by
Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
GOC:dos
A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
dos
2017-09-22T14:14:36Z
This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.
has effector activity
A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
GOC:dos
David Osumi-Sutherland
<=
Primitive instance level timing relation between events
before or simultaneous with
David Osumi-Sutherland
t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2)
simultaneous with
David Osumi-Sutherland
Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.
during which ends
David Osumi-Sutherland
di
Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.
encompasses
David Osumi-Sutherland
X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)
ends after
X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)
David Osumi-Sutherland
starts_at_end_of
A non-transitive temporal relation in which one process immediately precedes another process, such that there is no interval of time between the two processes[SIO:000251].
RO:0002087
directly preceded by
is directly preceded by
is immediately preceded by
starts_at_end_of
uberon
immediately_preceded_by
immediately_preceded_by
X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)
immediately preceded by
immediately_preceded_by
A non-transitive temporal relation in which one process immediately precedes another process, such that there is no interval of time between the two processes[SIO:000251].
SIO:000251
is immediately preceded by
SIO:000251
David Osumi-Sutherland
Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.
during which starts
David Osumi-Sutherland
ends_at_start_of
meets
X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
immediately precedes
David Osumi-Sutherland
io
RO:0002091
external
starts_during
starts_during
X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))
starts during
starts_during
David Osumi-Sutherland
d
during
RO:0002092
external
happens_during
happens_during
X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))
happens during
happens during
David Osumi-Sutherland
o
overlaps
RO:0002093
external
ends_during
ends_during
X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y).
ends during
ends_during
Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]
Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.
Alexander Diehl
Chris Mungall
Lindsay Cowell
<http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y)
has plasma membrane part
A overlaps B if they share some part in common.
x overlaps y if and only if there exists some z such that x has part z and z part of y
x overlaps y iff they have some part in common.
BFO_0000051 some (BFO_0000050 some ?Y)
http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
RO:0002131
spatial
uberon
overlaps
overlaps
"(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF []
overlaps
overlaps
true
x overlaps y iff they have some part in common.
BSPO:cjm
d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.
ancestral_stucture_of
evolutionarily_descended_from
derived by descent from
inverse of derived by descent from
has derived by descendant
two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.
Consider obsoleting and merging with child relation, 'in homology relationship with'
VBO calls this homologous_to
shares ancestor with
serially homologous to
lactation SubClassOf 'only in taxon' some 'Mammalia'
x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.
'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria
Chris Mungall
only in taxon
x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
Chris Mungall
Jennifer Deegan
Connects a biological entity to its taxon of origin.
in taxon
A is spatially_disjoint_from B if and only if they have no parts in common
There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom.
Chris Mungall
Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy
BFO_0000051 exactly 0 (BFO_0000050 some ?Y)
spatially disjoint from
https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern
a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
connected to
https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern
https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern
a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
attached to part of (anatomical structure to anatomical structure)
attached to part of
true
w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
RO:0002180
uberon
has_component
has_component
has component
has component
A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).
Chris Mungall
has phenotype
inverse of has phenotype
Chris Mungall
phenotype of
x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
Chris Mungall
David Osumi-Sutherland
Melissa Haendel
Terry Meehan
RO:0002202
uberon
develops_from
develops_from
This is the transitive form of the develops from relation
develops from
develops_from
inverse of develops from
Chris Mungall
David Osumi-Sutherland
Terry Meehan
RO:0002203
uberon
develops_into
develops_into
develops into
develops_into
Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.
Chris Mungall
David Osumi-Sutherland
has developmental precursor
FBbt
TODO - add child relations from DOS
directly develops from
inverse of directly develops from
developmental precursor of
directly develops into
process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.
We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit
Chris Mungall
David Hill
Tanya Berardini
GO
Regulation precludes parthood; the regulatory process may not be within the regulated process.
regulates (processual)
false
RO:0002211
external
regulates
regulates
regulates
regulates
Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
Chris Mungall
negatively regulates (process to process)
RO:0002212
external
negatively_regulates
negatively_regulates
negatively regulates
negatively regulates
Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
Chris Mungall
positively regulates (process to process)
RO:0002213
external
positively_regulates
positively_regulates
positively regulates
positively regulates
mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
osteoclast SubClassOf 'capable of' some 'bone resorption'
A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
Chris Mungall
has function realized in
For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
RO_0000053 some (RO_0000054 only ?Y)
RO:0002215
uberon
capable_of
capable_of
capable of
capable of
c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
Chris Mungall
has function in
RO_0000053 some (RO_0000054 only (BFO_0000050 some ?Y))
RO:0002216
uberon
capable_of_part_of
capable_of_part_of
capable of part of
capable of part of
true
OBSOLETE x actively participates in y if and only if x participates in y and x realizes some active role
x actively participates in y if and only if x participates in y and x realizes some active role
Chris Mungall
agent in
Obsoleted as the inverse property was obsoleted.
actively participates in
obsolete actively participates in
true
'heart development' has active participant some Shh protein
x has participant y if and only if x realizes some active role that inheres in y
This may be obsoleted and replaced by the original 'has agent' relation
Chris Mungall
has agent
obsolete has active participant
true
x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
Chris Mungall
surrounded by
A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
The epidermis layer of a vertebrate is adjacent to the dermis.
The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.
The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.
x adjacent to y if and only if x and y share a boundary.
x adjacent_to y iff: x and y share a boundary
This relation acts as a join point with BSPO
Chris Mungall
RO:0002220
spatial
uberon
adjacent_to
adjacent_to
adjacent to
adjacent to
adjacent_to
A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
inverse of surrounded by
Chris Mungall
surrounds
Chris Mungall
Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1
A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.
temporally related to
inverse of starts with
Chris Mungall
Allen
starts
Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor
x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
Chris Mungall
started by
starts with
x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
Chris Mungall
develops from part of
x develops_in y if x is located in y whilst x is developing
Chris Mungall
EHDAA2
Jonathan Bard, EHDAA2
develops in
inverse of ends with
Chris Mungall
ends
x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
Chris Mungall
finished by
ends with
x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y
Chris Mungall
starts with process that occurs in
has start location
x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
Chris Mungall
ends with process that occurs in
has end location
p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
Chris Mungall
consumes
has input
Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
x has developmental contribution from y iff x has some part z such that z develops from y
Chris Mungall
RO:0002254
uberon
has_developmental_contribution_from
has_developmental_contribution_from
has developmental contribution from
has developmental contribution from
inverse of has developmental contribution from
Chris Mungall
RO:0002255
uberon
developmentally_contributes_to
developmentally_contributes_to
developmentally contributes to
developmentally_contributes_to
t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T
Chris Mungall
David Osumi-Sutherland
Melissa Haendel
induced by
Developmental Biology, Gilbert, 8th edition, figure 6.5(F)
GO:0001759
We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]
developmentally induced by
Inverse of developmentally induced by
Chris Mungall
developmentally induces
Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
false
Chris Mungall
In general you should not use this relation to make assertions - use one of the more specific relations below this one
RO:0002258
uberon
developmentally_preceded_by
developmentally_preceded_by
This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from
developmentally preceded by
developmentally preceded by
A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
acts upstream of
A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
affects
acts upstream of or within
x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else
This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage
Chris Mungall
replaces
developmentally replaces
Inverse of developmentally preceded by
Chris Mungall
developmentally succeeded by
'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue
Chris Mungall
part of developmental precursor of
cjm
holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y
causally upstream of, positive effect
cjm
holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y
causally upstream of, negative effect
q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.
Because part_of is transitive, inheres in is a sub-relation of inheres in part of
Chris Mungall
inheres in part of
true
A relationship that holds via some environmental process
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.
evolutionarily related to
A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions
ecologically related to
An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial.
Chris Mungall
adapted for
confers advantage in
A mereological relationship or a topological relationship
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
mereotopologically related to
A relationship that holds between entities participating in some developmental process (GO:0032502)
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development
developmentally related to
ATP citrate lyase (ACL) in Arabidopsis: it is a heterooctamer, composed of two types of subunits, ACLA and ACLB in a A(4)B(4) stoichiometry. Neither of the subunits expressed alone give ACL activity, but co-expression results in ACL activity. Both subunits contribute_to the ATP citrate lyase activity.
Subunits of nuclear RNA polymerases: none of the individual subunits have RNA polymerase activity, yet all of these subunits contribute_to DNA-dependent RNA polymerase activity.
eIF2: has three subunits (alpha, beta, gamma); one binds GTP; one binds RNA; the whole complex binds the ribosome (all three subunits are required for ribosome binding). So one subunit is annotated to GTP binding and one to RNA binding without qualifiers, and all three stand in the contributes_to relationship to "ribosome binding". And all three are part_of an eIF2 complex
We would like to say
if and only if
exists c', p'
c part_of c' and c' capable_of p
and
c capable_of p' and p' part_of p
then
c contributes_to p
However, this is not possible in OWL. We instead make this relation a sub-relation of the two chains, which gives us the inference in the one direction.
Chris Mungall
http://www.geneontology.org/GO.annotation.conventions.shtml#contributes_to
In the context of the Gene Ontology, contributes_to may be used only with classes from the molecular function ontology.
contributes to
a particular instances of akt-2 enables some instance of protein kinase activity
Chris Mungall
catalyzes
executes
has
is catalyzing
is executing
This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.
This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time.
enables
A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
Chris Mungall
This is a grouping relation that collects relations used for the purpose of connecting structure and function
RO:0002328
uberon
functionally_related_to
functionally_related_to
functionally related to
functionally related to
this relation holds between c and p when c is part of some c', and c' is capable of p.
Chris Mungall
false
RO:0002329
uberon
part_of_structure_that_is_capable_of
part_of_structure_that_is_capable_of
part of structure that is capable of
part of structure that is capable of
true
c involved_in p if and only if c enables some process p', and p' is part of p
Chris Mungall
actively involved in
enables part of
involved in
inverse of enables
Chris Mungall
enabled by
inverse of regulates
Chris Mungall
regulated by (processual)
regulated by
inverse of negatively regulates
Chris Mungall
negatively regulated by
inverse of positively regulates
Chris Mungall
positively regulated by
inverse of has input
Chris Mungall
RO:0002352
uberon
input_of
input_of
input of
input of
a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
Chris Mungall
attached to (anatomical structure to anatomical structure)
attached to
m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.
Chris Mungall
Wikipedia:Insertion_(anatomy)
has muscle origin
We need to import uberon muscle to create a stricter domain constraint
m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.
Chris Mungall
Wikipedia:Insertion_(anatomy)
has muscle insertion
We need to import uberon muscle into RO to use as a stricter domain constraint
false
x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat
Chris Mungall
Chris Mungall
has fused element
A has_fused_element B does not imply that A has_part some B: rather than A has_part some B', where B' that has some evolutionary relationship to B.
derived from ancestral fusion of
A lump of clay and a statue
x spatially_coextensive_with y if and inly if x and y have the same location
Chris Mungall
This relation is added for formal completeness. It is unlikely to be used in many practical scenarios
spatially coextensive with
x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
Chris Mungall
has developmental potential involving
x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
Chris Mungall
RO:0002385
uberon
has_potential_to_developmentally_contribute_to
has_potential_to_developmentally_contribute_to
has potential to developmentally contribute to
has potential to developmentally contribute to
x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y
Chris Mungall
has potential to developmentally induce
x has the potential to develop into y iff x develops into y or if x is capable of developing into y
x has the potential to develop into y iff x develops into y or if x is capable of developing into y
Chris Mungall
RO:0002387
uberon
has_potential_to_develop_into
has_potential_to_develop_into
has potential to develop into
has potential to develop into
x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
Chris Mungall
RO:0002388
uberon
has_potential_to_directly_develop_into
has_potential_to_directly_develop_into
has potential to directly develop into
has potential to directly develop into
inverse of upstream of
Chris Mungall
causally downstream of
Chris Mungall
immediately causally downstream of
This relation groups causal relations between material entities and causal relations between processes
This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.
To define causal relations in an activity-flow type network, we make use of 3 primitives:
* Temporal: how do the intervals of the two occurrents relate?
* Is the causal relation regulatory?
* Is the influence positive or negative
The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.
For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.
For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.
Each of these 3 primitives can be composed to yield a cross-product of different relation types.
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causally related to
p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain
Chris Mungall
causally upstream of
p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.
Chris Mungall
immediately causally upstream of
p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.
We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
Chris Mungall
influences (processual)
affects
causally upstream of or within
inverse of causally upstream of or within
Chris Mungall
causally downstream of or within
c involved in regulation of p if c is involved in some p' and p' regulates some p
Chris Mungall
involved in regulation of
c involved in regulation of p if c is involved in some p' and p' positively regulates some p
Chris Mungall
involved in positive regulation of
c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
Chris Mungall
involved in negative regulation of
c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
OWL does not allow defining object properties via a Union
Chris Mungall
involved in or reguates
involved in or involved in regulation of
A protein that enables activity in a cytosol.
c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
Chris Mungall
executes activity in
enables activity in
is active in
true
c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
GOC:cjm
GOC:dos
A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
Considering relabeling as 'pairwise interacts with'
This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
Chris Mungall
Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.
in pairwise interaction with
interacts with
http://purl.obolibrary.org/obo/MI_0914
https://github.com/oborel/obo-relations/wiki/InteractionRelations
An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
Chris Mungall
binds
molecularly binds with
molecularly interacts with
http://purl.obolibrary.org/obo/MI_0915
Axiomatization to GO to be added later
Chris Mungall
An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.
phosphorylates
Holds between molecular entities A and B where A can physically interact with B and in doing so regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
Chris Mungall
Vasundra Touré
molecularly controls
activity directly regulates activity of
directly regulates activity of
Holds between molecular entities A and B where A can physically interact with B and in doing so negatively regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
Chris Mungall
Vasundra Touré
directly inhibits
inhibits
molecularly decreases activity of
activity directly negatively regulates activity of
directly negatively regulates activity of
Holds between molecular entities A and B where A can physically interact with B and in doing so positively regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
Chris Mungall
Vasundra Touré
activates
directly activates
molecularly increases activity of
activity directly positively regulates activity of
directly positively regulates activity of
Chris Mungall
This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.
helper property (not for use in curation)
Chris Mungall
is symbiosis
'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
Chris Mungall
composed primarily of
p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
Chris Mungall
has part that occurs in
true
Chris Mungall
is kinase activity
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.
relation between physical entity and a process or stage
x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).
Chris Mungall
existence starts during
x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
Chris Mungall
The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
existence overlaps
x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
Chris Mungall
The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
existence ends during
x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).
Chris Mungall
RO:0002496
uberon
existence_starts_during_or_after
existence_starts_during_or_after
The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
existence starts during or after
x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
Chris Mungall
RO:0002497
uberon
existence_ends_during_or_before
existence_ends_during_or_before
The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
existence ends during or before
A relationship between a material entity and a process where the material entity has some causal role that influences the process
causal agent in process
p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causal relation between processes
Chris Mungall
depends on
q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2
This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.
Chris Mungall
towards
The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causal relation between entities
causal relation between material entities
Chris Mungall
causally influenced by (entity-centric)
causally influenced by (material entity to material entity)
causally influenced by
Chris Mungall
interaction relation helper property
https://github.com/oborel/obo-relations/wiki/InteractionRelations
Chris Mungall
molecular interaction relation helper property
Holds between materal entities a and b if the activity of a is causally upstream of the activity of b, or causally upstream of a an activity that modifies b
The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
Chris Mungall
Vasundra Touré
causally influences (entity-centric)
causally influences (material entity to material entity)
causally influences
A relation that holds between elements of a musculoskeletal system or its analogs.
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.
biomechanically related to
A relation that holds between an attribute or a qualifier and another attribute.
Chris Mungall
This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the "modifiers" are.
has modifier
Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
Chris Mungall
directly regulates (processual)
directly regulates
holds between x and y if and only if the time point at which x starts is equivalent to the time point at which y ends. Formally: iff α(x) = ω(y).
existence starts at end of
gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
Chris Mungall
has part structure that is capable of
holds between x and y if and only if the time point at which x ends is equivalent to the time point at which y starts. Formally: iff ω(x) = α(y).
existence ends at start of
A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
Chris Mungall
causal relation between material entity and a process
pyrethroid -> growth
Holds between c and p if and only if c is capable of some activity a, and a regulates p.
capable of regulating
Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
capable of negatively regulating
renin -> arteriolar smooth muscle contraction
Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
capable of positively regulating
Inverse of 'causal agent in process'
process has causal agent
A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
obsolete related via dependence to
true
Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.
directly positively regulates (process to process)
directly positively regulates
Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.
directly negatively regulates (process to process)
directly negatively regulates
a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
Melissa Haendel
RO:0003000
uberon
produces
produces
Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.
produces
produces
a produced_by b iff some process that occurs_in b has_output a.
Melissa Haendel
RO:0003001
uberon
produced_by
produced_by
produced by
produced_by
A relationship between a disease and some feature of that disease, where the feature is either a phenotype or an isolated disease.
cjm
2017-12-26T19:50:53Z
disease has feature
Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
cjm
2018-01-25T23:20:13Z
enables subfunction
cjm
2018-01-26T23:49:30Z
acts upstream of or within, positive effect
cjm
2018-01-26T23:49:51Z
acts upstream of or within, negative effect
c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
cjm
2018-01-26T23:53:14Z
acts upstream of, positive effect
c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
cjm
2018-01-26T23:53:22Z
acts upstream of, negative effect
cjm
2018-03-13T23:55:05Z
causally upstream of or within, negative effect
cjm
2018-03-13T23:55:19Z
causally upstream of or within, positive effect
The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
Vasundra Touré
regulates activity of
This relation groups relations between diseases and any other kind of entity.
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a disease.
cjm
2018-09-26T00:00:32Z
disease relationship
x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross.
spatial
parallel_to
parallel to
x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross.
BSPO:curators
quality
correlates_with
correlates_with
q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
quality
decreased_in_magnitude_relative_to
This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.
decreased_in_magnitude_relative_to
q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
PATOC:CJM
q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
quality
different_in_magnitude_relative_to
different_in_magnitude_relative_to
q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
PATOC:CJM
s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
quality
has_cross_section
Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.
has_cross_section
s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
PATOC:CJM
q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
quality
increased_in_magnitude_relative_to
This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.
increased_in_magnitude_relative_to
q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
PATOC:CJM
q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.
quality
reciprocal_of
There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality.
reciprocal_of
q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.
PATOC:CJM
An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
continuant
An entity that has temporal parts and that happens, unfolds or develops through time.
occurrent
A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
independent continuant
spatial region
An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
process
disposition
A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
realizable entity
quality
A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
specifically dependent continuant
A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
generically dependent continuant
An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
material entity
immaterial entity
A 2D surface of an anatomical continuant.
FMA:24137
surface
spatial
BSPO:0000005
to be merged into CARO
anatomical surface
A 2D surface of an anatomical continuant.
BSPO:cjm
A straight line through space, intersecting an anatomical entity.
http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG
spatial
BSPO:0000010
Axis directions are defined in terms of axes.
anatomical axis
A straight line through space, intersecting an anatomical entity.
BSPO:cjm
An axis that extends through an organism from head end to opposite end of body or tail.
A-P axis
AP axis
anteroposterior axis
cephalocaudal axis
craniocaudal axis
rostral/caudal
rostrocaudal axis
spatial
longitudinal axis
BSPO:0000013
In sponges, AP is used to indicate the direction of movement [in larval stage] (as it is in other metazoans that move, e.g., the basal bilaterians). [PM]
anterior-posterior axis
An axis that extends through an organism from head end to opposite end of body or tail.
BSPO:cjm
cephalocaudal axis
http://en.wikipedia.org/wiki/Anatomical_terms_of_location
craniocaudal axis
rostral/caudal
rostrocaudal axis
An axis that extends through an organism or organism part from the part of the organism or organism part attached to a substrate (basal) to the furthest from the attachment (apical). Note that the apical-basal axis is often used for organismal parts where there is attachment via a basal lamina or other structure.
apical/basal
spatial
longitudinal axis
BSPO:0000014
apical-basal axis relative to substrate
An axis that extends through an organism or organism part from the part of the organism or organism part attached to a substrate (basal) to the furthest from the attachment (apical). Note that the apical-basal axis is often used for organismal parts where there is attachment via a basal lamina or other structure.
BSPO:mah
An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal).
proximal/distal
proximodistal
spatial
BSPO:0000015
In some communities, proximal and distal are used when specifying the position of parts of elements that are contained within the body, such as gill arches or vertebral spines. In these cases, use of the classes medial-lateral axis or medial-external axis are more appropriate.
proximal-distal axis
An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal).
BSPO:curators
http://en.wikipedia.org/wiki/Anatomical_terms_of_location
An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body.
D-V axis
DV axis
dorsoventral axis
anterior-posterior axis
spatial
BSPO:0000016
dorsal-ventral axis
An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body.
BSPO:curators
anterior-posterior axis
An axis that bisects an organism from left to right sides of body, through a sagittal plane.
L-R axis
LR axis
R-L axis
RL axis
dextro-sinister axis
left to right axis
right to left axis
right-left axis
spatial
BSPO:0000017
left-right axis
An axis that bisects an organism from left to right sides of body, through a sagittal plane.
BSPO:cjm
Anatomical plane that divides body into anterior and posterior parts.
FMA:12247
axial plane
axial section
transverse section
spatial
cross-section
BSPO:0000018
transverse plane
Anatomical plane that divides body into anterior and posterior parts.
BSPO:mah
Anatomical plane that divides bilateral body into dorsal and ventral parts.
FMA:52810
frontal plane
horizontal anatomical plane
horizontal section
spatial
coronal section
frontal section
BSPO:0000019
horizontal plane
Anatomical plane that divides bilateral body into dorsal and ventral parts.
BSPO:mah
horizontal anatomical plane
FMA:52810
Anatomical region that overlaps the anterior and dorsal regions of a body or body part.
Melissa Haendel
2009-06-15T01:01:38Z
anterodorsal region
spatial
BSPO:0000026
antero-dorsal region
Anatomical region that overlaps the anterior and dorsal regions of a body or body part.
BSPO:wd
Anatomical region that overlaps the anterior and ventral regions of a body or body part.
Melissa Haendel
2009-06-15T01:04:59Z
anteroventral region
spatial
BSPO:0000027
antero-ventral region
Anatomical region that overlaps the anterior and ventral regions of a body or body part.
BSPO:wd
Anatomical region that overlaps the posterior and lateral regions of the body or body part.
Melissa Haendel
2009-06-15T01:06:01Z
posterolateral region
spatial
BSPO:0000028
postero-lateral region
Anatomical region that overlaps the posterior and lateral regions of the body or body part.
BSPO:wd
Anatomical region that overlaps the anterior and lateral regions of a body or body part.
Melissa Haendel
2009-06-15T01:07:18Z
anterolateral region
spatial
BSPO:0000029
antero-lateral region
Anatomical region that overlaps the anterior and lateral regions of a body or body part.
BSPO:wd
Anatomical region that overlaps the posterior and dorsal regions of the body or body part.
Melissa Haendel
2009-06-15T01:08:13Z
posterodorsal region
spatial
BSPO:0000030
postero-dorsal region
Anatomical region that overlaps the posterior and dorsal regions of the body or body part.
BSPO:wd
Anatomical region that overlaps the posterior and ventral regions of a body or body part.
Melissa Haendel
2009-06-15T01:08:38Z
posteroventral region
spatial
BSPO:0000035
postero-ventral region
Anatomical region that overlaps the posterior and ventral regions of a body or body part.
BSPO:wd
An anatomical region bounded by a plane perpendicular to an axis through the middle.
FBql:00005841
spatial
BSPO:0000054
anatomical side
An anatomical region bounded by a plane perpendicular to an axis through the middle.
BSPO:cjm
An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane.
FBcv:0000053
FBql:00005848
anterior
rostral
spatial
BSPO:0000055
anterior side
An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane.
BSPO:RW
An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane.
FBcv:0000065
FBql:00005849
posterior
caudal
spatial
BSPO:0000056
posterior side
An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane.
BSPO:RW
BSPO:wd
caudal
Anatomical side that is located on the apical end of an organism or structure.
FBcv:0000054
FBql:00005854
apical
spatial
BSPO:0000057
apical side
Anatomical side that is located on the apical end of an organism or structure.
BSPO:wd
Anatomical side that is located on the basal end of an organism or structure.
FBcv:0000055
FBql:00005855
basal
spatial
BSPO:0000058
The part of the organism attached to a substrate. Axis of symmetry.
basal side
Anatomical side that is located on the basal end of an organism or structure.
BSPO:wd
An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane.
FBcv:0000059
FBql:00005842
dorsal
spatial
BSPO:0000063
dorsal side
An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane.
BSPO:wd
FBcv:0000063
FBql:00005844
lateral
spatial
BSPO:0000066
lateral side
An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane.
FBcv:0000070
FBql:00005843
ventral
spatial
BSPO:0000068
ventral side
An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane.
BSPO:RW
BSPO:wd
A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm.
FBql:00005841
spatial
BSPO:0000070
to be merged into CARO
anatomical region
A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm.
BSPO:cjm
Anatomical region anteriorly located on the body or body part.
FBql:00005848
spatial
BSPO:0000071
anterior region
Anatomical region anteriorly located on the body or body part.
BSPO:wd
Anatomical region posteriorly located on the body or body part.
FBql:00005849
spatial
BSPO:0000072
posterior region
Anatomical region posteriorly located on the body or body part.
BSPO:wd
Anatomical region located on the apical end on the body or body part.
FBql:00005854
spatial
BSPO:0000073
apical region
Anatomical region located on the apical end on the body or body part.
BSPO:wd
Anatomical region located basally on the body or body part.
FBql:00005855
spatial
BSPO:0000074
basal region
Anatomical region located basally on the body or body part.
BSPO:wd
Anatomical region dorsally located on the body or body part.
FBql:00005842
spatial
BSPO:0000079
dorsal region
Anatomical region dorsally located on the body or body part.
BSPO:wd
Anatomical region that overlaps the dorsal and lateral regions of a body or body part.
FBql:00005845
dorsolateral region
spatial
BSPO:0000080
dorso-lateral region
Anatomical region that overlaps the dorsal and lateral regions of a body or body part.
BSPO:wd
Anatomical region laterally located on the body or body part.
FBql:00005844
spatial
BSPO:0000082
lateral region
Anatomical region laterally located on the body or body part.
BSPO:wd
Anatomical region ventrally located on the body or body part.
FBql:00005843
spatial
BSPO:0000084
ventral region
Anatomical region ventrally located on the body or body part.
BSPO:wd
Anatomical region that overlaps the ventral and lateral regions of a body or body part.
FBql:00005846
ventrolateral region
spatial
BSPO:0000085
This is an example of a composition of two axis positions.
ventro-lateral region
Anatomical region that overlaps the ventral and lateral regions of a body or body part.
BSPO:wd
FBql:00005873
FMA:9647
spatial
BSPO:0000086
to be merged into CARO
anatomical compartment
FBcv:0000036
FBql:00005875
spatial
BSPO:0000090
posterior compartment
FBql:00005881
spatial
BSPO:0000092
to be merged into CARO
anatomical compartment boundary
FBcv:0000034
FBql:00005879
spatial
BSPO:0000094
dorsal/ventral compartment boundary
An anatomical axis that extends from the center of the body outwards or externally.
wasila.dahdul
2013-07-02T11:21:42Z
spatial
proximal-distal axis
BSPO:0000196
The medial-external axis could apply to a sphere-shaped body.
medial-external axis
An anatomical axis that extends from the center of the body outwards or externally.
BSPO:curators
An axis that extends from the oral opening to the furthest point in an organism that is directly opposite.
wasila.dahdul
2013-07-02T11:29:33Z
spatial
BSPO:0000198
oral-aboral axis
An axis that extends from the oral opening to the furthest point in an organism that is directly opposite.
BSPO:PM
Anatomical surface that is located on the anterior side of the body or body part.
FBql:00005848
spatial
BSPO:0000371
anterior surface
Anatomical surface that is located on the anterior side of the body or body part.
BSPO:wd
Anatomical surface that is located on the posterior side of the body or body part.
FBql:00005849
spatial
BSPO:0000372
posterior surface
Anatomical surface that is located on the posterior side of the body or body part.
BSPO:wd
Anatomical surface that is located on the apical side of the body or body part.
FBql:00005854
spatial
BSPO:0000373
apical surface
Anatomical surface that is located on the apical side of the body or body part.
BSPO:wd
Anatomical surface that is located on the basal side of the body or body part.
FBql:00005855
spatial
BSPO:0000374
basal surface
Anatomical surface that is located on the basal side of the body or body part.
BSPO:wd
Anatomical surface that located on the dorsal side of the body or body part.
FBql:00005842
spatial
BSPO:0000379
dorsal surface
Anatomical surface that located on the dorsal side of the body or body part.
BSPO:wd
Anatomical surface that located on the lateral side of the body or body part.
FBql:00005844
spatial
BSPO:0000382
lateral surface
Anatomical surface that located on the lateral side of the body or body part.
BSPO:wd
Anatomical surface that is located on the ventral side of the body or body part.
FBql:00005843
spatial
BSPO:0000384
ventral surface
Anatomical surface that is located on the ventral side of the body or body part.
BSPO:wd
A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions.
FMA:242982
anatomical cross-section
anatomical section
plane
section
spatial
cross-section
BSPO:0000400
These anatomical sections are applicable to most bilaterally symmetrical animals, but bipedal animals such as humans have more complex usage of these terms. For example, in post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical.
anatomical plane
A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions.
BSPO:cjm
Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size.
FMA:11361
left/right plane
median plane
sagittal section
spatial
BSPO:0000417
sagittal plane
Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size.
BSPO:DOS
BSPO:cjm
BSPO:mah
An axis that extends from the center of organism to one or other side.
http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG
M-L axis
ML axis
medio-lateral axis
mediolateral axis
spatial
proximal-distal axis
BSPO:0001001
Properly, the ML axis is a half axis; practically, its usage is less clumsy and less linguistically biased than "left-right". The terms may still be used relatively to describe locations along the LR axis. The gills are medial to the operculum, but lateral to the heart.
medial-lateral axis
An axis that extends from the center of organism to one or other side.
BSPO:cjm
Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
spatial
CARO:0000000
anatomical entity
anatomical entity
Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
CARO:MAH
Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
spatial
CARO:0000003
anatomical structure
connected anatomical structure
Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
CC:DOS
An anatomical entity that has mass.
spatial
CARO:0000006
material anatomical entity
material anatomical entity
An anatomical entity that has mass.
CC:DOS
An anatomical entity that has no mass.
spatial
CARO:0000007
immaterial anatomical entity
An anatomical entity that has no mass.
CC:DOS
A one dimensional, immaterial anatomical entity.
spatial
CARO:0000008
anatomical line
A one dimensional, immaterial anatomical entity.
CC:DOS
A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures.
spatial
CARO:0000010
anatomical boundary
A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures.
CC:DOS
cell part (CARO)
cell part
organism or virus or viroid
multicellular anatomical structure
biological entity
cell
neuron
environmental system
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
biological_process
GO:0000002
mitochondrial genome maintenance
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
GOC:ai
GOC:vw
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
GO:0019952
GO:0050876
Wikipedia:Reproduction
reproductive physiological process
biological_process
GO:0000003
reproduction
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
GOC:go_curators
GOC:isa_complete
GOC:jl
ISBN:0198506732
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
spindle elongation during mitosis
biological_process
GO:0000022
mitotic spindle elongation
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
GOC:mtg_cell_cycle
GOC:vw
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
autophagic vacuole assembly
autophagosome biosynthesis
autophagosome formation
PAS formation
biological_process
autophagic vacuole formation
GO:0000045
autophagosome assembly
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
GOC:autophagy
PMID:9412464
autophagic vacuole assembly
GOC:autophagy
autophagic vacuole formation
GOC:mah
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
GO:0016359
mitotic chromosome segregation
mitotic sister-chromatid adhesion release
biological_process
GO:0000070
mitotic sister chromatid segregation
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
GOC:ai
GOC:jl
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
MIPS_funcat:10.03.01.01.01
G1 phase of mitotic cell cycle
biological_process
GO:0000080
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic G1 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
GOC:mtg_cell_cycle
The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
MIPS_funcat:10.03.01.01.05
S phase of mitotic cell cycle
S-phase of mitotic cell cycle
biological_process
GO:0000084
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic S phase
The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
GOC:mtg_cell_cycle
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
MIPS_funcat:10.03.01.01.07
G2 phase of mitotic cell cycle
biological_process
GO:0000085
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic G2 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
GOC:mtg_cell_cycle
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
M phase of mitotic cell cycle
M-phase of mitotic cell cycle
biological_process
GO:0000087
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic M phase
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
GOC:mtg_cell_cycle
The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
biological_process
GO:0000088
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic prophase
The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GOC:mtg_cell_cycle
The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.
biological_process
GO:0000089
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic metaphase
The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.
GOC:mtg_cell_cycle
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.
biological_process
GO:0000090
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic anaphase
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.
GOC:mtg_cell_cycle
The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
biological_process
GO:0000093
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic telophase
The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GOC:mtg_cell_cycle
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
GO:0010553
GO:0045816
down regulation of transcription from RNA polymerase II promoter
down-regulation of transcription from RNA polymerase II promoter
downregulation of transcription from RNA polymerase II promoter
inhibition of transcription from RNA polymerase II promoter
negative regulation of transcription from Pol II promoter
negative regulation of transcription from RNA polymerase II promoter
biological_process
down regulation of global transcription from RNA polymerase II promoter
down-regulation of global transcription from RNA polymerase II promoter
downregulation of global transcription from RNA polymerase II promoter
inhibition of global transcription from RNA polymerase II promoter
negative regulation of gene-specific transcription from RNA polymerase II promoter
negative regulation of global transcription from Pol II promoter
negative regulation of transcription from RNA polymerase II promoter, global
GO:0000122
negative regulation of transcription by RNA polymerase II
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
GOC:go_curators
GOC:txnOH
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
GO:0043147
meiotic spindle organisation
spindle organization during meiosis
biological_process
meiotic spindle organization and biogenesis
meiotic spindle stabilization
GO:0000212
meiotic spindle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
GOC:go_curators
GOC:mah
spindle organization during meiosis
GOC:mah
meiotic spindle organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
microtubule cytoskeleton organisation
microtubule dynamics
biological_process
microtubule cytoskeleton organization and biogenesis
GO:0000226
microtubule cytoskeleton organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GOC:mah
microtubule cytoskeleton organisation
GOC:mah
microtubule dynamics
GOC:dph
GOC:tb
microtubule cytoskeleton organization and biogenesis
GOC:mah
The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.
Wikipedia:Leptotene
Wikipedia:Meiosis#Leptotene
biological_process
GO:0000237
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
leptotene
The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.
GOC:mtg_cell_cycle
The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.
Wikipedia:Meiosis#Zygotene
Wikipedia:Zygotene
biological_process
GO:0000238
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
zygotene
The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.
GOC:mtg_cell_cycle
The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
Wikipedia:Meiosis#Pachytene
Wikipedia:Pachytene
biological_process
GO:0000239
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
pachytene
The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
GOC:mtg_cell_cycle
The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
Wikipedia:Diplotene
Wikipedia:Meiosis#Diplotene
biological_process
GO:0000240
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
diplotene
The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
GOC:mtg_cell_cycle
The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.
Wikipedia:Diakinesis
Wikipedia:Meiosis#Diakinesis
biological_process
GO:0000241
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
diakinesis
The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.
GOC:mtg_cell_cycle
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0007067
MIPS_funcat:10.03.01
MIPS_funcat:10.03.01.01
Wikipedia:Mitosis
biological_process
mitosis
GO:0000278
mitotic cell cycle
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GOC:mah
ISBN:0815316194
Reactome:69278
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.
Wikipedia:M_phase
M-phase
biological_process
GO:0000279
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
M phase
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.
GOC:mtg_cell_cycle
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
MIPS_funcat:10.03.04
MIPS_funcat:10.03.04.07
biological_process
karyokinesis
GO:0000280
nuclear division
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
GOC:mah
A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
cellular_component
GO:0000323
lytic vacuole
A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
GOC:krc
The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.
biological_process
GO:0000819
sister chromatid segregation
The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.
GOC:ai
GOC:elh
The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
biological_process
GO:0000959
mitochondrial RNA metabolic process
The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GOC:krc
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
response to acid
biological_process
response to acid anion
response to oxoanion
GO:0001101
This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.
response to acid chemical
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GOC:go_curators
GOC:rn
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
retinoid metabolism
biological_process
GO:0001523
retinoid metabolic process
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
ISBN:0198506732
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
Wikipedia:Angiogenesis
blood vessel formation from pre-existing blood vessels
biological_process
GO:0001525
angiogenesis
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
ISBN:0878932453
blood vessel formation from pre-existing blood vessels
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
ciliary/flagellar motility
biological_process
ciliary or bacterial-type flagellar motility
GO:0001539
Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.
cilium or flagellum-dependent cell motility
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
GOC:cilia
GOC:hjd
GOC:krc
Any process that modulates the frequency, rate, extent or direction of cell growth.
biological_process
GO:0001558
regulation of cell growth
Any process that modulates the frequency, rate, extent or direction of cell growth.
GOC:go_curators
Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
interpretation of external signals that regulate cell growth
regulation of cell growth by detection of exogenous stimulus
regulation of cell growth by sensing of exogenous stimulus
regulation of growth by exogenous signal
regulation of growth by exogenous stimuli
regulation of growth by exogenous stimulus
regulation of growth by external signal
regulation of growth by external stimuli
regulation of growth by external stimulus
biological_process
GO:0001560
regulation of cell growth by extracellular stimulus
Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
GOC:dph
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
biological_process
GO:0001568
blood vessel development
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
GOC:hjd
UBERON:0001981
A process that results in a parallel arrangement of microtubules.
microtubule bundling
biological_process
GO:0001578
microtubule bundle formation
A process that results in a parallel arrangement of microtubules.
GOC:dph
A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
Wikipedia:Conditioned_taste_aversion
Wikipedia:Taste_aversion
biological_process
GO:0001661
conditioned taste aversion
A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
GOC:dph
PMID:9920659
The formation of the acrosome from the spermatid Golgi.
acrosome formation
biological_process
GO:0001675
acrosome assembly
The formation of the acrosome from the spermatid Golgi.
GOC:dph
GOC:hjd
GOC:tb
acrosome formation
GOC:dph
GOC:tb
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
biological_process
GO:0001775
cell activation
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GOC:mgi_curators
A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.
Wikipedia:Autolysis
biological_process
GO:0001896
autolysis
A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.
GOC:add
GOC:jh2
GOC:mtg_apoptosis
PMID:10974124
PMID:19286987
PMID:26811896
Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
biological_process
necrosis
GO:0001906
cell killing
Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GOC:add
Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
GO:0001907
killing by symbiont of host cells
Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:add
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
regulation of protein amino acid phosphorylation
biological_process
GO:0001932
regulation of protein phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
GOC:hjd
regulation of protein amino acid phosphorylation
GOC:bf
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
down regulation of protein amino acid phosphorylation
down-regulation of protein amino acid phosphorylation
downregulation of protein amino acid phosphorylation
negative regulation of protein amino acid phosphorylation
inhibition of protein amino acid phosphorylation
biological_process
GO:0001933
negative regulation of protein phosphorylation
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
GOC:hjd
negative regulation of protein amino acid phosphorylation
GOC:bf
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of protein amino acid phosphorylation
up regulation of protein amino acid phosphorylation
up-regulation of protein amino acid phosphorylation
upregulation of protein amino acid phosphorylation
activation of protein amino acid phosphorylation
stimulation of protein amino acid phosphorylation
biological_process
GO:0001934
positive regulation of protein phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
GOC:hjd
positive regulation of protein amino acid phosphorylation
GOC:bf
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
biological_process
vascular system development
GO:0001944
vasculature development
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
GOC:dph
UBERON:0002409
The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.
biological_process
healing during inflammatory response
inflammatory response wound healing
GO:0002246
wound healing involved in inflammatory response
The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.
GOC:jal
ISBN:0721601871
healing during inflammatory response
GOC:dph
inflammatory response wound healing
GOC:dph
An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
Wikipedia:Adaptive_immune_system
acquired immune response
immune memory response
biological_process
GO:0002250
adaptive immune response
An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GOC:add
GO_REF:0000022
ISBN:0781735149
acquired immune response
ISBN:068340007X
immune memory response
GOC:add
Any process of the immune system that can potentially contribute to an immune response.
biological_process
GO:0002252
immune effector process
Any process of the immune system that can potentially contribute to an immune response.
GOC:add
GO_REF:0000022
ISBN:0781735149
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
biological_process
GO:0002262
myeloid cell homeostasis
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
CL:0000763
GOC:add
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
biological_process
cell activation during immune response
GO:0002263
cell activation involved in immune response
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GOC:add
GO_REF:0000022
ISBN:0781735149
cell activation during immune response
GOC:tb
A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.
biological_process
immune cell activation during inflammatory response
leukocyte activation during inflammatory response
GO:0002269
leukocyte activation involved in inflammatory response
A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.
GOC:add
ISBN:0781735149
leukocyte activation during inflammatory response
GOC:tb
A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
myeloid leucocyte activation
biological_process
GO:0002274
myeloid leukocyte activation
A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
GOC:add
ISBN:0781735149
A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
biological_process
myeloid cell activation during immune response
GO:0002275
myeloid cell activation involved in immune response
A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GOC:add
ISBN:0781735149
myeloid cell activation during immune response
GOC:tb
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
macrophage polarization involved in immune response
biological_process
macrophage activation during immune response
GO:0002281
macrophage activation involved in immune response
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GOC:add
ISBN:0781735149
macrophage activation during immune response
GOC:tb
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
biological_process
lymphocyte activation during immune response
GO:0002285
lymphocyte activation involved in immune response
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GOC:add
ISBN:0781735149
lymphocyte activation during immune response
GOC:tb
The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
biological_process
NK cell activation during immune response
natural killer cell activation during immune response
GO:0002323
natural killer cell activation involved in immune response
The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GOC:add
PMID:15032583
natural killer cell activation during immune response
GOC:tb
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
biological_process
immune cell activation during immune response
leucocyte activation during immune response
leukocyte activation during immune response
GO:0002366
leukocyte activation involved in immune response
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GOC:add
ISBN:0781735149
leukocyte activation during immune response
GOC:tb
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
Wikipedia:Immune_system
biological_process
GO:0002376
Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GOC:add
GO_REF:0000022
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
biological_process
GO:0002437
inflammatory response to antigenic stimulus
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
GOC:add
ISBN:0781735149
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
biological_process
GO:0002438
acute inflammatory response to antigenic stimulus
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
GOC:add
GO_REF:0000022
ISBN:0781735149
Any process involved in the carrying out of an immune response by a leukocyte.
GO:0019723
GO:0042087
immune cell effector process
immune cell mediated immunity
leucocyte immune effector process
leucocyte mediated immunity
leukocyte immune effector process
biological_process
cell-mediated immune response
cellular immune response
GO:0002443
leukocyte mediated immunity
Any process involved in the carrying out of an immune response by a leukocyte.
GOC:add
GO_REF:0000022
ISBN:0781735149
Any process involved in the carrying out of an immune response by a myeloid leukocyte.
myeloid leucocyte immune effector process
myeloid leucocyte mediated immunity
myeloid leukocyte immune effector process
biological_process
GO:0002444
myeloid leukocyte mediated immunity
Any process involved in the carrying out of an immune response by a myeloid leukocyte.
GOC:add
GO_REF:0000022
ISBN:0781735149
An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
Wikipedia:Type_II_hypersensitivity
biological_process
GO:0002445
type II hypersensitivity
An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
GOC:add
ISBN:0781735149
Any process involved in the carrying out of an immune response by a lymphocyte.
cell-mediated immunity
cellular immune response
biological_process
GO:0002449
lymphocyte mediated immunity
Any process involved in the carrying out of an immune response by a lymphocyte.
GOC:add
GO_REF:0000022
ISBN:0781735149
An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
biological_process
GO:0002460
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
GOC:add
GOC:mtg_sensu
ISBN:0781735149
ISBN:1405196831
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
biological_process
GO:0002520
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GOC:add
GOC:dph
An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
Wikipedia:Hypersensitivity
biological_process
hypersensitivity response
GO:0002524
hypersensitivity
An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
GOC:jal
ISBN:0781735149
hypersensitivity response
ISBN:0781735149
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
biological_process
GO:0002526
acute inflammatory response
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
GOC:add
GO_REF:0000022
ISBN:0781735149
Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
biological_process
GO:0002673
regulation of acute inflammatory response
Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
down regulation of acute inflammatory response
down-regulation of acute inflammatory response
downregulation of acute inflammatory response
inhibition of acute inflammatory response
biological_process
GO:0002674
negative regulation of acute inflammatory response
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
up regulation of acute inflammatory response
up-regulation of acute inflammatory response
upregulation of acute inflammatory response
activation of acute inflammatory response
stimulation of acute inflammatory response
biological_process
GO:0002675
positive regulation of acute inflammatory response
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
GOC:add
Any process that modulates the frequency, rate, or extent of an immune system process.
biological_process
GO:0002682
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
down regulation of immune system process
down-regulation of immune system process
downregulation of immune system process
inhibition of immune system process
biological_process
GO:0002683
negative regulation of immune system process
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an immune system process.
up regulation of immune system process
up-regulation of immune system process
upregulation of immune system process
activation of immune system process
stimulation of immune system process
biological_process
GO:0002684
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
GOC:add
Any process that modulates the frequency, rate, or extent of leukocyte activation.
regulation of immune cell activation
regulation of leucocyte activation
biological_process
GO:0002694
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
down regulation of leukocyte activation
down-regulation of leukocyte activation
downregulation of leukocyte activation
negative regulation of immune cell activation
negative regulation of leucocyte activation
inhibition of leukocyte activation
biological_process
GO:0002695
negative regulation of leukocyte activation
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
GOC:add
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
positive regulation of immune cell activation
positive regulation of leucocyte activation
up regulation of leukocyte activation
up-regulation of leukocyte activation
upregulation of leukocyte activation
activation of leukocyte activation
stimulation of leukocyte activation
biological_process
GO:0002696
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
GOC:add
Any process that modulates the frequency, rate, or extent of an immune effector process.
biological_process
GO:0002697
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
down regulation of immune effector process
down-regulation of immune effector process
downregulation of immune effector process
inhibition of immune effector process
biological_process
GO:0002698
negative regulation of immune effector process
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an immune effector process.
up regulation of immune effector process
up-regulation of immune effector process
upregulation of immune effector process
activation of immune effector process
stimulation of immune effector process
biological_process
GO:0002699
positive regulation of immune effector process
Any process that activates or increases the frequency, rate, or extent of an immune effector process.
GOC:add
Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
regulation of immune cell mediated immunity
regulation of leucocyte mediated immunity
biological_process
GO:0002703
regulation of leukocyte mediated immunity
Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
down regulation of leukocyte mediated immunity
down-regulation of leukocyte mediated immunity
downregulation of leukocyte mediated immunity
negative regulation of immune cell mediated immunity
negative regulation of leucocyte mediated immunity
inhibition of leukocyte mediated immunity
biological_process
GO:0002704
negative regulation of leukocyte mediated immunity
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
positive regulation of immune cell mediated immunity
positive regulation of leucocyte mediated immunity
up regulation of leukocyte mediated immunity
up-regulation of leukocyte mediated immunity
upregulation of leukocyte mediated immunity
activation of leukocyte mediated immunity
stimulation of leukocyte mediated immunity
biological_process
GO:0002705
positive regulation of leukocyte mediated immunity
Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
GOC:add
Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
biological_process
GO:0002706
regulation of lymphocyte mediated immunity
Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
down regulation of lymphocyte mediated immunity
down-regulation of lymphocyte mediated immunity
downregulation of lymphocyte mediated immunity
inhibition of lymphocyte mediated immunity
biological_process
GO:0002707
negative regulation of lymphocyte mediated immunity
Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
up regulation of lymphocyte mediated immunity
up-regulation of lymphocyte mediated immunity
upregulation of lymphocyte mediated immunity
activation of lymphocyte mediated immunity
stimulation of lymphocyte mediated immunity
biological_process
GO:0002708
positive regulation of lymphocyte mediated immunity
Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
GOC:add
Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
regulation of B lymphocyte mediated immunity
regulation of B-cell mediated immunity
regulation of B-lymphocyte mediated immunity
biological_process
GO:0002712
regulation of B cell mediated immunity
Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
down regulation of B cell mediated immunity
down-regulation of B cell mediated immunity
downregulation of B cell mediated immunity
negative regulation of B lymphocyte mediated immunity
negative regulation of B-cell mediated immunity
negative regulation of B-lymphocyte mediated immunity
inhibition of B cell mediated immunity
biological_process
GO:0002713
negative regulation of B cell mediated immunity
Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
positive regulation of B lymphocyte mediated immunity
positive regulation of B-cell mediated immunity
positive regulation of B-lymphocyte mediated immunity
up regulation of B cell mediated immunity
up-regulation of B cell mediated immunity
upregulation of B cell mediated immunity
activation of B cell mediated immunity
stimulation of B cell mediated immunity
biological_process
GO:0002714
positive regulation of B cell mediated immunity
Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
GOC:add
The controlled release of a peptide from a cell or a tissue.
biological_process
GO:0002790
peptide secretion
The controlled release of a peptide from a cell or a tissue.
GOC:add
Any process that modulates the frequency, rate, or extent of peptide secretion.
biological_process
GO:0002791
regulation of peptide secretion
Any process that modulates the frequency, rate, or extent of peptide secretion.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
down regulation of peptide secretion
down-regulation of peptide secretion
downregulation of peptide secretion
inhibition of peptide secretion
biological_process
GO:0002792
negative regulation of peptide secretion
Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
GOC:add
Any process that activates or increases the frequency, rate, or extent of peptide secretion.
up regulation of peptide secretion
up-regulation of peptide secretion
upregulation of peptide secretion
activation of peptide secretion
stimulation of peptide secretion
biological_process
GO:0002793
positive regulation of peptide secretion
Any process that activates or increases the frequency, rate, or extent of peptide secretion.
GOC:add
true
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
biological_process
GO:0002819
regulation of adaptive immune response
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
down regulation of adaptive immune response
down-regulation of adaptive immune response
downregulation of adaptive immune response
inhibition of adaptive immune response
biological_process
GO:0002820
negative regulation of adaptive immune response
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.
up regulation of adaptive immune response
up-regulation of adaptive immune response
upregulation of adaptive immune response
activation of adaptive immune response
stimulation of adaptive immune response
biological_process
GO:0002821
positive regulation of adaptive immune response
Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.
GOC:add
Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
biological_process
GO:0002822
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GOC:add
GOC:mtg_sensu
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
biological_process
GO:0002823
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GOC:add
GOC:mtg_sensu
Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
biological_process
GO:0002824
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GOC:add
GOC:mtg_sensu
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
biological_process
GO:0002831
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to biotic stimulus
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
down regulation of response to biotic stimulus
down-regulation of response to biotic stimulus
downregulation of response to biotic stimulus
inhibition of response to biotic stimulus
biological_process
GO:0002832
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to biotic stimulus
Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
up regulation of response to biotic stimulus
up-regulation of response to biotic stimulus
upregulation of response to biotic stimulus
activation of response to biotic stimulus
stimulation of response to biotic stimulus
biological_process
GO:0002833
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to biotic stimulus
Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
biological_process
GO:0002861
regulation of inflammatory response to antigenic stimulus
Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
down regulation of inflammatory response to antigenic stimulus
down-regulation of inflammatory response to antigenic stimulus
downregulation of inflammatory response to antigenic stimulus
inhibition of inflammatory response to antigenic stimulus
biological_process
GO:0002862
negative regulation of inflammatory response to antigenic stimulus
Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
up regulation of inflammatory response to antigenic stimulus
up-regulation of inflammatory response to antigenic stimulus
upregulation of inflammatory response to antigenic stimulus
activation of inflammatory response to antigenic stimulus
stimulation of inflammatory response to antigenic stimulus
biological_process
GO:0002863
positive regulation of inflammatory response to antigenic stimulus
Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GOC:add
Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
biological_process
GO:0002864
regulation of acute inflammatory response to antigenic stimulus
Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
down regulation of acute inflammatory response to antigenic stimulus
down-regulation of acute inflammatory response to antigenic stimulus
downregulation of acute inflammatory response to antigenic stimulus
inhibition of acute inflammatory response to antigenic stimulus
biological_process
GO:0002865
negative regulation of acute inflammatory response to antigenic stimulus
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
up regulation of acute inflammatory response to antigenic stimulus
up-regulation of acute inflammatory response to antigenic stimulus
upregulation of acute inflammatory response to antigenic stimulus
activation of acute inflammatory response to antigenic stimulus
stimulation of acute inflammatory response to antigenic stimulus
biological_process
GO:0002866
positive regulation of acute inflammatory response to antigenic stimulus
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GOC:add
Any process that modulates the frequency, rate, or extent of hypersensitivity.
biological_process
GO:0002883
regulation of hypersensitivity
Any process that modulates the frequency, rate, or extent of hypersensitivity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
down regulation of hypersensitivity
down-regulation of hypersensitivity
downregulation of hypersensitivity
inhibition of hypersensitivity
biological_process
GO:0002884
negative regulation of hypersensitivity
Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
up regulation of hypersensitivity
up-regulation of hypersensitivity
upregulation of hypersensitivity
activation of hypersensitivity
stimulation of hypersensitivity
biological_process
GO:0002885
positive regulation of hypersensitivity
Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
GOC:add
Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
biological_process
GO:0002886
regulation of myeloid leukocyte mediated immunity
Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
down regulation of myeloid leukocyte mediated immunity
down-regulation of myeloid leukocyte mediated immunity
downregulation of myeloid leukocyte mediated immunity
inhibition of myeloid leukocyte mediated immunity
biological_process
GO:0002887
negative regulation of myeloid leukocyte mediated immunity
Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
up regulation of myeloid leukocyte mediated immunity
up-regulation of myeloid leukocyte mediated immunity
upregulation of myeloid leukocyte mediated immunity
activation of myeloid leukocyte mediated immunity
stimulation of myeloid leukocyte mediated immunity
biological_process
GO:0002888
positive regulation of myeloid leukocyte mediated immunity
Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GOC:add
Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
biological_process
GO:0002889
regulation of immunoglobulin mediated immune response
Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
down regulation of immunoglobulin mediated immune response
down-regulation of immunoglobulin mediated immune response
downregulation of immunoglobulin mediated immune response
inhibition of immunoglobulin mediated immune response
biological_process
GO:0002890
negative regulation of immunoglobulin mediated immune response
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
up regulation of immunoglobulin mediated immune response
up-regulation of immunoglobulin mediated immune response
upregulation of immunoglobulin mediated immune response
activation of immunoglobulin mediated immune response
stimulation of immunoglobulin mediated immune response
biological_process
GO:0002891
positive regulation of immunoglobulin mediated immune response
Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
GOC:add
Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
biological_process
GO:0002892
regulation of type II hypersensitivity
Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.
down regulation of type II hypersensitivity
down-regulation of type II hypersensitivity
downregulation of type II hypersensitivity
inhibition of type II hypersensitivity
biological_process
GO:0002893
negative regulation of type II hypersensitivity
Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.
GOC:add
Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
up regulation of type II hypersensitivity
up-regulation of type II hypersensitivity
upregulation of type II hypersensitivity
activation of type II hypersensitivity
stimulation of type II hypersensitivity
biological_process
GO:0002894
positive regulation of type II hypersensitivity
Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
GOC:add
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
puberty
biological_process
reproductive developmental process
GO:0003006
developmental process involved in reproduction
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
GOC:dph
GOC:isa_complete
puberty
GOC:dph
reproductive developmental process
GOC:dph
GOC:tb
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
organ system process
biological_process
GO:0003008
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
GOC:mtg_cardio
A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
excretory system process
biological_process
kidney system process
GO:0003014
renal system process
A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
GOC:cjm
GOC:mtg_cardio
GOC:mtg_kidney_jan10
The directed, self-propelled movement of a cilium.
dph
2009-11-24T09:56:26Z
GO:0036142
microtubule-based flagellum movement
flagellar movement
flagellum movement
biological_process
ciliary motility
cilium beating
flagellar motility
GO:0003341
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium movement
The directed, self-propelled movement of a cilium.
GOC:dph
GOC:jl
flagellar movement
GOC:bf
cilium beating
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
dph
2009-12-03T10:12:00Z
GO:1900172
regulation of microtubule-based flagellum movement
biological_process
regulation of flagellar movement
regulation of flagellum movement
GO:0003352
Note that we deem cilium and microtubule-based flagellum to be equivalent.
regulation of cilium movement
Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GOC:dph
regulation of flagellar movement
GOC:TermGenie
Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
dph
2009-12-03T10:16:10Z
GO:1900174
positive regulation of microtubule-based flagellum movement
biological_process
positive regulation of flagellar movement
positive regulation of flagellum movement
GO:0003353
Note that we deem cilium and microtubule-based flagellum to be equivalent.
positive regulation of cilium movement
Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GOC:dph
positive regulation of flagellar movement
GOC:TermGenie
Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
dph
2009-12-03T10:17:47Z
GO:1900173
negative regulation of microtubule-based flagellum movement
biological_process
negative regulation of flagellum movement
GO:0003354
Note that we deem cilium and microtubule-based flagellum to be equivalent.
negative regulation of cilium movement
Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GOC:dph
A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
molecular process
GO:0005554
molecular function
molecular_function
GO:0003674
Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
molecular_function
A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
GOC:pdt
Interacting selectively and non-covalently with any nucleic acid.
GO:0000496
base pairing
molecular_function
GO:0003676
nucleic acid binding
Interacting selectively and non-covalently with any nucleic acid.
GOC:jl
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0043566
plasmid binding
molecular_function
microtubule/chromatin interaction
structure specific DNA binding
structure-specific DNA binding
GO:0003677
DNA binding
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
GOC:vw
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
molecular_function
GO:0003707
Some steroid hormone receptors reside in the plasma membrane and signal through second messengers or other intracellular signal transduction pathways. For steroid hormone receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: nuclear receptor activity ; GO:0004879' or nuclear receptor transcription coactivator activity ; GO:0030374'.
steroid hormone receptor activity
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
GOC:signaling
PMID:14708019
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Wikipedia:Enzyme
enzyme activity
molecular_function
GO:0003824
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GOC:vw
ISBN:0198506732
enzyme activity
GOC:dph
GOC:tb
true
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
GO:0004926
GO:0099600
transmembrane receptor activity
Reactome:R-HSA-193672
transmembrane signalling receptor activity
molecular_function
GO:0004888
This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
transmembrane signaling receptor activity
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
GOC:go_curators
Wikipedia:Transmembrane_receptor
transmembrane receptor activity
GOC:bf
GOC:signaling
Reactome:R-HSA-193672
Sphingomyelinase is activated by the NGF:p75NTR complex
transmembrane signalling receptor activity
GOC:mah
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001622
GO:0001623
GO:0001624
GO:0001625
GO:0016526
Reactome:R-HSA-114552
Reactome:R-HSA-114558
Reactome:R-HSA-167408
Wikipedia:GPCR
G protein coupled receptor activity
G protein linked receptor activity
G-protein coupled receptor activity
G-protein linked receptor activity
GPCR activity
ligand-dependent GPCR activity
receptor activity, G-protein coupled
EBV-induced receptor
Epstein-Barr Virus-induced receptor activity
G-protein coupled receptor activity, unknown ligand
Mas proto-oncogene receptor activity
RDC1 receptor activity
SREB receptor
orphan G protein coupled receptor activity
orphan G-protein coupled receptor activity
orphan GPCR activity
super conserved receptor expressed in brain receptor activity
molecular_function
GO:0004930
G protein-coupled receptor activity
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GOC:bf
Wikipedia:GPCR
http://www.iuphar-db.org
Reactome:R-HSA-114552
G12/13 activation by PAR
Reactome:R-HSA-114558
Gq activation by PAR
Reactome:R-HSA-167408
The high affinity receptor complex binds to G-protein
receptor activity, G-protein coupled
GOC:bf
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
receptor binding
Wikipedia:Ligand_(biochemistry)
receptor ligand
molecular_function
receptor-associated protein activity
GO:0005102
Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.
signaling receptor binding
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GOC:bf
GOC:ceb
ISBN:0198506732
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0005478
EC:7
Reactome:R-HSA-168313
Reactome:R-HSA-178215
molecular_function
carrier
GO:0005215
Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GOC:ai
GOC:dgf
Reactome:R-HSA-168313
Virion-associated M2 protein mediated ion infusion
Reactome:R-HSA-178215
SMAD7:SMURF1 complex is exported to the cytosol
Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
GO:0005312
GO:0015365
Reactome:R-HSA-1614546
Reactome:R-HSA-372843
dicarboxylate carrier
sodium:dicarboxylate/tricarboxylate symporter activity
molecular_function
dicarboxylate (succinate/fumarate/malate) antiporter activity
dicarboxylic acid permease activity
GO:0005310
dicarboxylic acid transmembrane transporter activity
Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
GOC:ai
Reactome:R-HSA-1614546
Sulfate is exported to the cytosol in exchange for dicarboxylate
Reactome:R-HSA-372843
malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage,
molecular_function
GO:0005342
organic acid transmembrane transporter activity
Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage,
ISBN:0198506732
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
Wikipedia:Binding_(molecular)
ligand
molecular_function
GO:0005488
Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GOC:ceb
GOC:mah
ISBN:0198506732
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0001948
GO:0045308
MIPS_funcat:16.01
MIPS_funcat:18.01.07
Reactome:R-HSA-170835
Reactome:R-HSA-170846
protein amino acid binding
glycoprotein binding
molecular_function
GO:0005515
protein binding
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GOC:go_curators
Reactome:R-HSA-170835
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
Reactome:R-HSA-170846
TGFBR2 recruits TGFBR1
A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
GO:0008372
NIF_Subcellular:sao1337158144
cell or subcellular entity
cellular component
cellular_component
subcellular entity
GO:0005575
Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this.
cellular_component
A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
GOC:pdt
NIF_Subcellular:sao1337158144
subcellular entity
NIF_Subcellular:nlx_subcell_100315
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
MIPS_funcat:70.27
Wikipedia:Extracellular
extracellular
cellular_component
GO:0005576
Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
GOC:go_curators
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
NIF_Subcellular:sao1425028079
cellular_component
intercellular space
GO:0005615
Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
ISBN:0198547684
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
Wikipedia:Cell_wall
cellular_component
GO:0005618
cell wall
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
GOC:giardia
ISBN:0198547684
PMID:15134259
Wikipedia:Microbial_cyst
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
Wikipedia:Intracellular
internal to cell
protoplasm
cellular_component
nucleocytoplasm
protoplast
GO:0005622
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
ISBN:0198506732
nucleocytoplasm
GOC:mah
protoplast
GOC:mah
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cell and encapsulating structures
NIF_Subcellular:sao1813327414
Wikipedia:Cell_(biology)
cellular_component
GO:0005623
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:go_curators
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
MIPS_funcat:70.10
NIF_Subcellular:sao1702920020
Wikipedia:Cell_nucleus
cell nucleus
horsetail nucleus
cellular_component
GO:0005634
nucleus
nucleus
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GOC:go_curators
horsetail nucleus
GOC:al
GOC:mah
GOC:vw
PMID:15030757
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
NIF_Subcellular:sao1820400233
Wikipedia:Nucleolus
cellular_component
GO:0005730
nucleolus
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
ISBN:0198506732
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Wikipedia:Cytoplasm
cellular_component
GO:0005737
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ISBN:0198547684
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
NIF_Subcellular:sao1860313010
Wikipedia:Mitochondrion
mitochondria
cellular_component
GO:0005739
Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GOC:giardia
ISBN:0198506732
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
cellular_component
GO:0005740
mitochondrial envelope
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
GOC:ai
GOC:pz
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
GO:0031971
NIF_Subcellular:sao118944228
mitochondrial envelope lumen
cellular_component
mitochondrial membrane lumen
GO:0005758
mitochondrial intermembrane space
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
GOC:mah
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
GO:0031980
NIF_Subcellular:sao1804523077
Wikipedia:Mitochondrial_matrix
mitochondrial lumen
mitochondrial stroma
cellular_component
GO:0005759
mitochondrial matrix
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
GOC:as
ISBN:0198506732
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
NIF_Subcellular:sao585356902
Wikipedia:Lysosome
cellular_component
GO:0005764
lysosome
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
GOC:mah
ISBN:0198506732
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
Wikipedia:Vacuole
cellular_component
vacuolar carboxypeptidase Y
GO:0005773
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
GOC:mtg_sensu
ISBN:0198506732
The volume enclosed within the vacuolar membrane.
cellular_component
GO:0005775
vacuolar lumen
The volume enclosed within the vacuolar membrane.
ISBN:0198506732
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
NIF_Subcellular:sao1036339110
Wikipedia:Endoplasmic_reticulum
ER
cellular_component
GO:0005783
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
ISBN:0198506732
The volume enclosed by the membranes of the endoplasmic reticulum.
GO:0016022
ER cisterna
ER lumen
cisternal lumen
endoplasmic reticulum cisterna
cellular_component
GO:0005788
endoplasmic reticulum lumen
The volume enclosed by the membranes of the endoplasmic reticulum.
ISBN:0198547684
The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
NIF_Subcellular:sao710427438
Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum
SER
smooth ER
cellular_component
GO:0005790
smooth endoplasmic reticulum
The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
ISBN:0198506732
The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
NIF_Subcellular:sao1881364067
Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum
RER
rough ER
cellular_component
GO:0005791
rough endoplasmic reticulum
The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
ISBN:0198506732
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Golgi
NIF_Subcellular:sao451912436
Wikipedia:Golgi_apparatus
Golgi complex
Golgi ribbon
cellular_component
GO:0005794
Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.
Golgi apparatus
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
ISBN:0198506732
Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
NIF_Subcellular:sao819927218
cellular_component
Golgi vesicle
vesicular component
GO:0005798
Note that this definition includes vesicles that are transiently associated with the Golgi.
Golgi-associated vesicle
Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
GOC:mah
vesicular component
NIF_Subcellular:sao138219748
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
cis face
NIF_Subcellular:sao632188024
cis Golgi network
cellular_component
Golgi cis face
Golgi cis-face
forming face
GO:0005801
The CGN is not considered part of the Golgi apparatus but is a separate organelle.
cis-Golgi network
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
ISBN:0198506732
ISBN:0815316194
cis face
NIF_Subcellular:sao632188024
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
adiposome
lipid body
lipid particle
cellular_component
GO:0005811
Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers.
lipid droplet
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
GOC:mah
GOC:tb
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
Wikipedia:Spindle_apparatus
cellular_component
GO:0005819
spindle
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
ISBN:0198547684
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
NIF_Subcellular:sao101633890
Wikipedia:Cytosol
cellular_component
GO:0005829
cytosol
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GOC:hjd
GOC:jl
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
NIF_Subcellular:sao1038025871
Wikipedia:Polysome
polyribosome
cellular_component
GO:0005844
polysome
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
ISBN:0198506732
NIF_Subcellular:sao1038025871
polyribosome
NIF_Subcellular:sao1038025871
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Wikipedia:Cytoskeleton
cellular_component
GO:0005856
cytoskeleton
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GOC:mah
ISBN:0198547684
PMID:16959967
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0005904
juxtamembrane
NIF_Subcellular:sao1663586795
Wikipedia:Cell_membrane
cell membrane
cellular membrane
cytoplasmic membrane
plasmalemma
bacterial inner membrane
inner endospore membrane
plasma membrane lipid bilayer
cellular_component
GO:0005886
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
ISBN:0716731363
cellular membrane
NIF_Subcellular:sao6433132645
plasma membrane lipid bilayer
GOC:mah
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
GO:0072372
FMA:67181
NIF_Subcellular:sao787716553
Wikipedia:Cilium
eukaryotic flagellum
microtubule-based flagellum
primary cilium
cellular_component
flagellum
GO:0005929
Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.
cilium
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
GOC:cilia
GOC:curators
GOC:kmv
GOC:vw
ISBN:0198547684
PMID:16824949
PMID:17009929
PMID:20144998
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
Wikipedia:Cell_cortex
cellular_component
cell periphery
peripheral cytoplasm
GO:0005938
cell cortex
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
GOC:mah
ISBN:0815316194
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
janelomax
2012-10-23T15:40:34Z
GO:0044261
GO:0044723
Wikipedia:Carbohydrate_metabolism
carbohydrate metabolism
multicellular organismal carbohydrate metabolic process
biological_process
single-organism carbohydrate metabolic process
GO:0005975
carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GOC:mah
ISBN:0198506732
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
organic acid metabolism
biological_process
GO:0006082
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
ISBN:0198506732
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
regulation of carbohydrate metabolism
biological_process
GO:0006109
regulation of carbohydrate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
GOC:go_curators
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0055134
cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
biological_process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0006139
nucleobase-containing compound metabolic process
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:ai
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
regulation of nucleotide metabolism
biological_process
GO:0006140
regulation of nucleotide metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GOC:go_curators
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
purine nucleotide metabolism
purine metabolic process
purine metabolism
biological_process
GO:0006163
purine nucleotide metabolic process
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
MetaCyc:DENOVOPURINE2-PWY
purine nucleotide anabolism
purine nucleotide biosynthesis
purine nucleotide formation
purine nucleotide synthesis
biological_process
GO:0006164
purine nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0055132
DNA metabolism
cellular DNA metabolism
biological_process
GO:0006259
DNA metabolic process
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
ISBN:0198506732
The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
biological_process
GO:0006304
DNA modification
The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
GOC:jl
GOC:ma
The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.
biological_process
GO:0006305
DNA alkylation
The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.
ISBN:0716735970
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
Wikipedia:DNA_methylation
biological_process
GO:0006306
DNA methylation
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
GOC:ems
ISBN:0198506732
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
DNA condensation
DNA organisation
DNA organization
biological_process
GO:0006323
DNA packaging
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
GOC:mah
ISBN:0815316194
The cellular synthesis of RNA on a template of DNA.
GO:0006350
GO:0061018
GO:0061022
cellular transcription
transcription
Wikipedia:Transcription_(genetics)
DNA-dependent transcription
cellular transcription, DNA-dependent
transcription, DNA-dependent
biological_process
transcription regulator activity
GO:0006351
transcription, DNA-templated
The cellular synthesis of RNA on a template of DNA.
GOC:jl
GOC:txnOH
transcription, DNA-dependent
GOC:txnOH
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0032583
GO:0045449
GO:0061019
transcriptional control
regulation of cellular transcription, DNA-dependent
regulation of transcription, DNA-dependent
biological_process
regulation of gene-specific transcription
GO:0006355
regulation of transcription, DNA-templated
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
regulation of transcription, DNA-dependent
GOC:txnOH
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
GO:0006358
GO:0010551
regulation of transcription from Pol II promoter
regulation of transcription from RNA polymerase II promoter
biological_process
global transcription regulation from Pol II promoter
regulation of gene-specific transcription from RNA polymerase II promoter
regulation of global transcription from Pol II promoter
regulation of transcription from RNA polymerase II promoter, global
GO:0006357
regulation of transcription by RNA polymerase II
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
GOC:go_curators
GOC:txnOH
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
https://github.com/geneontology/go-ontology/issues/14854
GO:0032568
GO:0032569
transcription from Pol II promoter
transcription from RNA polymerase II promoter
biological_process
RNA polymerase II transcription factor activity
gene-specific transcription from RNA polymerase II promoter
general transcription from RNA polymerase II promoter
specific transcription from RNA polymerase II promoter
GO:0006366
transcription by RNA polymerase II
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
GOC:jl
GOC:txnOH
ISBN:0321000382
specific transcription from RNA polymerase II promoter
GOC:mah
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
https://github.com/geneontology/go-ontology/issues/14854
transcription from mitochondrial promoter
biological_process
GO:0006390
mitochondrial transcription
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
GOC:jl
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein modification process
biological_process
process resulting in protein modification
protein tagging activity
GO:0006464
cellular protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GOC:go_curators
protein modification process
GOC:bf
GOC:jl
The process of introducing a phosphate group on to a protein.
protein amino acid phosphorylation
biological_process
GO:0006468
protein phosphorylation
The process of introducing a phosphate group on to a protein.
GOC:hb
protein amino acid phosphorylation
GOC:bf
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GO:0065006
protein amino acid glycosylation
biological_process
protein-carbohydrate complex assembly
GO:0006486
protein glycosylation
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GOC:curators
GOC:pr
protein amino acid glycosylation
GOC:bf
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
RESID:AA0151
RESID:AA0156
RESID:AA0327
protein amino acid N-linked glycosylation
biological_process
N-glycan biosynthesis
N-glycan metabolism
GO:0006487
protein N-linked glycosylation
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
GOC:pr
RESID:AA0151
RESID:AA0156
RESID:AA0327
protein amino acid N-linked glycosylation
GOC:bf
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
Wikipedia:Proteolysis
peptidolysis
ATP-dependent proteolysis
biological_process
GO:0006508
This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing.
proteolysis
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GOC:bf
GOC:mah
ATP-dependent proteolysis
GOC:mah
The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
amino acid derivative metabolic process
cellular amino acid derivative metabolic process
cellular amino acid derivative metabolism
cellular modified amino acid metabolism
modified amino acid metabolic process
modified amino acid metabolism
biological_process
GO:0006575
cellular modified amino acid metabolic process
The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
GOC:ai
cellular modified amino acid metabolism
GOC:mah
modified amino acid metabolic process
GOC:mah
modified amino acid metabolism
GOC:mah
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
Wikipedia:Lipid_metabolism
lipid metabolism
biological_process
GO:0006629
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GOC:ma
The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0016096
isoprenoid metabolism
polyisoprenoid metabolic process
polyisoprenoid metabolism
polyterpene metabolic process
polyterpene metabolism
biological_process
GO:0006720
isoprenoid metabolic process
The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
ISBN:0198547684
The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
terpenoid metabolism
biological_process
GO:0006721
terpenoid metabolic process
The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
ISBN:0198506732
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
aromatic compound metabolism
aromatic hydrocarbon metabolic process
aromatic hydrocarbon metabolism
biological_process
GO:0006725
cellular aromatic compound metabolic process
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GOC:ai
ISBN:0198506732
The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
GO:0006752
coenzyme and prosthetic group metabolic process
coenzyme and prosthetic group metabolism
coenzyme metabolism
group transfer coenzyme metabolic process
group transfer coenzyme metabolism
biological_process
GO:0006732
coenzyme metabolic process
The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
ISBN:0198506732
The chemical reactions and pathways involving any phosphorylated nucleoside.
nucleoside phosphate metabolism
biological_process
GO:0006753
nucleoside phosphate metabolic process
The chemical reactions and pathways involving any phosphorylated nucleoside.
GOC:mah
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0006758
GO:0006759
ATP anabolism
ATP biosynthesis
ATP formation
ATP synthesis
ATP regeneration
biological_process
GO:0006754
ATP biosynthetic process
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
folate and derivative metabolic process
folate and derivative metabolism
folate-containing compound metabolic process
folate-containing compound metabolism
folic acid and derivative metabolic process
folic acid and derivative metabolism
folic acid-containing compound metabolism
vitamin B9 and derivative metabolic process
vitamin B9 and derivative metabolism
vitamin M and derivative metabolic process
vitamin M and derivative metabolism
biological_process
GO:0006760
folic acid-containing compound metabolic process
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
GOC:ai
GOC:mah
The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
vitamin metabolism
biological_process
GO:0006766
vitamin metabolic process
The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
GOC:ai
The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.
water-soluble vitamin metabolism
biological_process
GO:0006767
water-soluble vitamin metabolic process
The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.
GOC:jl
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
Wikipedia:Biotin
biotin metabolism
vitamin B7 metabolic process
vitamin B7 metabolism
vitamin H metabolic process
vitamin H metabolism
biological_process
GO:0006768
biotin metabolic process
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
ISBN:0198506732
The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
Wikipedia:Thiamine
thiamin metabolic process
thiamin metabolism
thiamine metabolism
vitamin B1 metabolic process
vitamin B1 metabolism
biological_process
GO:0006772
thiamine metabolic process
The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
fat-soluble vitamin metabolism
biological_process
GO:0006775
fat-soluble vitamin metabolic process
The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
vitamin A metabolism
biological_process
GO:0006776
vitamin A metabolic process
The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
GOC:jl
http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
Wikipedia:Sulfur_metabolism
sulfur metabolism
sulphur metabolic process
sulphur metabolism
biological_process
GO:0006790
sulfur compound metabolic process
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GOC:ai
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphorus metabolism
biological_process
GO:0006793
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GOC:ai
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
MIPS_funcat:01.04
phosphate metabolism
biological_process
phosphate metabolic process
GO:0006796
phosphate-containing compound metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GOC:ai
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
nitrogen compound metabolism
biological_process
GO:0006807
nitrogen compound metabolic process
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
GOC:jl
ISBN:0198506732
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
janelomax
2012-12-13T16:25:32Z
GO:0015457
GO:0015460
GO:0044765
small molecule transport
solute:solute exchange
biological_process
single-organism transport
GO:0006810
Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
GOC:dos
GOC:dph
GOC:jl
GOC:mah
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0006811
ion transport
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006822
biological_process
GO:0006820
anion transport
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006841
biological_process
sodium:dicarboxylate transport
GO:0006835
dicarboxylic acid transport
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:krc
The process in which a drug is transported across a membrane.
drug membrane transport
biological_process
multidrug transport
GO:0006855
Note that this term is not intended for use in annotating lateral movement within membranes.
drug transmembrane transport
The process in which a drug is transported across a membrane.
GOC:ai
GOC:bf
The transport of substances that occurs outside cells.
biological_process
GO:0006858
extracellular transport
The transport of substances that occurs outside cells.
GOC:go_curators
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
biological_process
GO:0006873
cellular ion homeostasis
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
regulation of calcium ion concentration
biological_process
GO:0006874
cellular calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
GOC:ceb
GOC:mah
Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
cellular heavy metal ion homeostasis
biological_process
GO:0006875
cellular metal ion homeostasis
Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
GOC:ai
GOC:mah
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0032779
biological_process
copper-induced intracellular protein transport
GO:0006886
intracellular protein transport
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GOC:mah
copper-induced intracellular protein transport
GOC:al
The evagination of a membrane, resulting in formation of a vesicle.
jl
2013-12-19T15:26:17Z
GO:0006902
GO:1902591
membrane evagination
vesicle biosynthesis
vesicle formation
biological_process
nonselective vesicle assembly
single organism membrane budding
single-organism membrane budding
vesicle budding
GO:0006900
vesicle budding from membrane
The evagination of a membrane, resulting in formation of a vesicle.
GOC:jid
GOC:tb
single organism membrane budding
GOC:TermGenie
The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
biological_process
GO:0006903
vesicle targeting
The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
GOC:mah
PMID:17335816
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GO:0016238
Wikipedia:Autophagy_(cellular)
biological_process
GO:0006914
autophagy
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GOC:autophagy
ISBN:0198547684
PMID:11099404
PMID:9412464
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0006917
GO:0008632
cell suicide
cellular suicide
Wikipedia:Apoptosis
apoptotic cell death
apoptotic programmed cell death
programmed cell death by apoptosis
activation of apoptosis
apoptosis
apoptosis signaling
apoptotic program
type I programmed cell death
biological_process
apoptosis activator activity
caspase-dependent programmed cell death
commitment to apoptosis
induction of apoptosis
induction of apoptosis by p53
signaling (initiator) caspase activity
GO:0006915
apoptotic process
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GOC:cjm
GOC:dhl
GOC:ecd
GOC:go_curators
GOC:mtg_apoptosis
GOC:tb
ISBN:0198506732
PMID:18846107
PMID:21494263
apoptotic cell death
GOC:sl
apoptotic program
GOC:add
The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.
cellular component disassembly involved in apoptotic process
disassembly of cell structures
cellular component disassembly involved in apoptosis
biological_process
GO:0006921
cellular component disassembly involved in execution phase of apoptosis
The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.
GOC:dph
GOC:mah
GOC:mtg_apoptosis
GOC:tb
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
cellular component motion
cellular component movement
biological_process
cell movement
GO:0006928
Note that in GO cellular components include whole cells (cell is_a cellular component).
movement of cell or subcellular component
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
GOC:dgh
GOC:dph
GOC:jl
GOC:mlg
cellular component motion
GOC:dph
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
response to abiotic stress
response to biotic stress
GO:0006950
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stress
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:mah
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0002217
GO:0042829
defence response
physiological defense response
biological_process
antimicrobial peptide activity
defense/immunity protein activity
GO:0006952
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GOC:go_curators
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
inflammation
Wikipedia:Inflammation
biological_process
GO:0006954
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
GO_REF:0000022
ISBN:0198506732
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
biological_process
GO:0006955
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GOC:add
GO_REF:0000022
A defense response that is mediated by cells.
https://github.com/geneontology/go-ontology/issues/18111
GO:0002818
GO:0016066
GO:0016067
cellular defence response
intracellular defence response
intracellular defense response
biological_process
GO:0006968
cellular defense response
A defense response that is mediated by cells.
GOC:ebc
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
osmotic response
osmotic stress response
biological_process
GO:0006970
response to osmotic stress
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
HOG response
hypertonic response
response to hypertonicity
biological_process
GO:0006972
hyperosmotic response
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
GOC:jl
PMID:12142009
response to hypertonicity
GOC:mah
GOC:yaf
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GO:0034984
response to DNA damage stimulus
DNA damage response
cellular DNA damage response
response to genotoxic stress
biological_process
GO:0006974
cellular response to DNA damage stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GOC:go_curators
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
jl
2013-12-19T15:25:51Z
GO:1902589
organelle organisation
single organism organelle organization
biological_process
organelle organization and biogenesis
single-organism organelle organization
GO:0006996
organelle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:mah
single organism organelle organization
GOC:TermGenie
organelle organization and biogenesis
GOC:dph
GOC:jl
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GO:0048287
nuclear organisation
nuclear organization
biological_process
nuclear morphology
nuclear organization and biogenesis
nucleus organization and biogenesis
GO:0006997
nucleus organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GOC:dph
GOC:ems
GOC:jl
GOC:mah
nuclear organization and biogenesis
GOC:mah
nucleus organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
mitochondria organization
mitochondrion organisation
biological_process
mitochondrion organization and biogenesis
GO:0007005
mitochondrion organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
GOC:dph
GOC:jl
GOC:mah
GOC:sgd_curators
PMID:9786946
mitochondria organization
GOC:mah
mitochondrion organisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
mitochondrial membrane organisation
biological_process
mitochondrial membrane organization and biogenesis
GO:0007006
mitochondrial membrane organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
mitochondrial membrane organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
cytoskeleton organisation
biological_process
cytoskeletal organization and biogenesis
cytoskeletal regulator activity
cytoskeleton organization and biogenesis
GO:0007010
cytoskeleton organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:dph
GOC:jl
GOC:mah
cytoskeletal organization and biogenesis
GOC:mah
cytoskeleton organization and biogenesis
GOC:mah
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
biological_process
GO:0007017
microtubule-based process
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GOC:mah
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
biological_process
GO:0007018
microtubule-based movement
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GOC:cjm
ISBN:0815316194
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0044086
vacuole organisation
vacuolar assembly
biological_process
vacuole biogenesis
vacuole organization and biogenesis
GO:0007033
vacuole organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GOC:mah
vacuolar assembly
GOC:mah
vacuole biogenesis
GOC:mah
vacuole organization and biogenesis
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.
biological_process
GO:0007036
vacuolar calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.
GOC:ai
GOC:mah
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
MIPS_funcat:10
MIPS_funcat:10.03
Wikipedia:Cell_cycle
cell-division cycle
biological_process
GO:0007049
cell cycle
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GOC:go_curators
GOC:mtg_cell_cycle
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
GO:0043146
spindle organisation
biological_process
spindle organization and biogenesis
spindle stabilization
GO:0007051
spindle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
GOC:go_curators
GOC:mah
spindle organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
https://github.com/geneontology/go-ontology/issues/15341
GO:0000071
GO:0030472
GO:0043148
mitotic spindle organisation
spindle organization and biogenesis during mitosis
mitotic spindle organisation in nucleus
mitotic spindle organization and biogenesis in cell nucleus
mitotic spindle organization and biogenesis in nucleus
mitotic spindle organization in nucleus
spindle organization and biogenesis in nucleus during mitosis
biological_process
mitotic spindle organization and biogenesis
mitotic spindle stabilization
GO:0007052
In fission yeast most mitotic spindle organization occurs in the nucleus.
mitotic spindle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
GOC:go_curators
GOC:mah
mitotic spindle organization and biogenesis
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
biological_process
GO:0007053
spindle assembly involved in male meiosis
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
GOC:mah
The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
biological_process
male meiosis II spindle assembly
GO:0007055
spindle assembly involved in male meiosis II
The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
biological_process
female meiotic spindle assembly
GO:0007056
spindle assembly involved in female meiosis
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
biological_process
female meiosis II spindle assembly
GO:0007058
spindle assembly involved in female meiosis II
The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
GOC:mah
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
Wikipedia:Chromosome_segregation
chromosome division
biological_process
chromosome transmission
GO:0007059
chromosome segregation
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
GOC:jl
GOC:mah
GOC:mtg_cell_cycle
GOC:vw
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
biological_process
GO:0007076
mitotic chromosome condensation
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
GOC:mah
ISBN:0815316194
Any process that modulates the frequency, rate or extent of mitosis.
regulation of mitosis
biological_process
GO:0007088
regulation of mitotic nuclear division
Any process that modulates the frequency, rate or extent of mitosis.
GOC:go_curators
The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
biological_process
GO:0007128
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic prophase I
The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GOC:mtg_cell_cycle
The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.
biological_process
GO:0007132
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic metaphase I
The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.
GOC:mtg_cell_cycle
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.
biological_process
GO:0007133
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic anaphase I
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.
GOC:mtg_cell_cycle
The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
biological_process
GO:0007134
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic telophase I
The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GOC:mtg_cell_cycle
The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
Wikipedia:Meiosis#Meiosis_II
meiosis II nuclear division
biological_process
GO:0007135
meiosis II
The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
GOC:dph
GOC:mah
ISBN:0198547684
The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
biological_process
GO:0007136
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic prophase II
The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GOC:mtg_cell_cycle
The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.
biological_process
GO:0007137
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic metaphase II
The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.
GOC:mtg_cell_cycle
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.
biological_process
GO:0007138
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic anaphase II
The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.
GOC:mtg_cell_cycle
The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
biological_process
GO:0007139
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic telophase II
The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GOC:mtg_cell_cycle
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
male nuclear division
biological_process
male meiosis
GO:0007140
male meiotic nuclear division
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
GOC:dph
GOC:mah
GOC:vw
A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.
male meiosis II nuclear division
biological_process
GO:0007142
male meiosis II
A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.
GOC:dph
GOC:mah
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
female meiosis
female meiotic division
biological_process
GO:0007143
Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.
female meiotic nuclear division
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
GOC:dph
GOC:ems
GOC:mah
GOC:vw
The cell cycle process in which the second meiotic division occurs in the female germline.
female meiosis II nuclear division
biological_process
GO:0007147
female meiosis II
The cell cycle process in which the second meiotic division occurs in the female germline.
GOC:mah
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
Wikipedia:Cell_signaling
biological_process
GO:0007154
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:mah
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
davidos
2014-04-15T15:59:10Z
GO:0098602
Wikipedia:Cell_adhesion
biological_process
cell adhesion molecule activity
single organism cell adhesion
GO:0007155
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GOC:hb
GOC:pf
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
down regulation of cell adhesion
down-regulation of cell adhesion
downregulation of cell adhesion
inhibition of cell adhesion
biological_process
cell adhesion receptor inhibitor activity
GO:0007162
negative regulation of cell adhesion
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
GOC:go_curators
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0023033
MIPS_funcat:30
Wikipedia:Signal_transduction
signaling cascade
signalling cascade
biological_process
signaling pathway
signalling pathway
GO:0007165
Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
signal transduction
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GOC:go_curators
GOC:mtg_signaling_feb11
signalling pathway
GOC:mah
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
GO:0038042
G protein coupled receptor protein signaling pathway
G protein coupled receptor protein signalling pathway
G-protein coupled receptor protein signal transduction
G-protein coupled receptor protein signaling pathway
G-protein coupled receptor signalling pathway
G-protein-coupled receptor protein signalling pathway
GPCR signaling pathway
GPCR signalling pathway
G-protein coupled receptor signaling pathway via GPCR dimer
dimeric G-protein coupled receptor signaling pathway
dimeric G-protein coupled receptor signalling pathway
biological_process
GO:0007186
G protein-coupled receptor signaling pathway
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
GOC:bf
GOC:mah
PMID:16902576
PMID:24568158
Wikipedia:G_protein-coupled_receptor
G-protein coupled receptor protein signaling pathway
GOC:bf
G-protein coupled receptor signaling pathway via GPCR dimer
GOC:bf
dimeric G-protein coupled receptor signalling pathway
GOC:mah
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
cell-cell signalling
biological_process
GO:0007267
cell-cell signaling
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
GOC:dos
GOC:mah
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
MIPS_funcat:41
biological_process
GO:0007275
Note that this term was 'developmental process'.
multicellular organism development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:dph
GOC:ems
GOC:isa_complete
GOC:tb
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
GO:0009552
biological_process
gametogenesis
GO:0007276
gamete generation
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
GOC:ems
GOC:mtg_sensu
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
germ-cell development
primordial germ cell development
biological_process
GO:0007281
germ cell development
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
GOC:go_curators
The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
Wikipedia:Spermatogenesis
generation of spermatozoa
biological_process
GO:0007283
spermatogenesis
The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
GOC:jid
ISBN:9780878933846
PMID:28073824
PMID:30990821
generation of spermatozoa
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
Wikipedia:Spermiogenesis
spermatid cell development
spermiogenesis
biological_process
GO:0007286
spermatid development
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
GOC:dph
GOC:go_curators
The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.
biological_process
GO:0007288
sperm axoneme assembly
The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.
GOC:bf
GOC:cilia
ISBN:0198547684
The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.
spermatid nuclear differentiation
biological_process
GO:0007289
See also the Cell Ontology term 'spermatid ; CL:0000018'.
spermatid nucleus differentiation
The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.
GOC:bf
GOC:dph
GOC:jl
GOC:mah
Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
biological_process
GO:0007292
female gamete generation
Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
GOC:dph
ISBN:0198506732
The union of male and female gametes to form a zygote.
MIPS_funcat:41.05.01
biological_process
zygote biosynthesis
zygote formation
GO:0007338
single fertilization
The union of male and female gametes to form a zygote.
GOC:ems
GOC:mtg_sensu
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
mitotic cell cycle modulation
mitotic cell cycle regulation
modulation of mitotic cell cycle progression
regulation of mitotic cell cycle progression
regulation of progression through mitotic cell cycle
biological_process
mitotic cell cycle regulator
GO:0007346
regulation of mitotic cell cycle
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
biological_process
pan-neural process
GO:0007399
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
GOC:dgh
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
Wikipedia:Neural_development
CNS development
biological_process
GO:0007417
central nervous system development
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GOC:bf
GOC:jid
ISBN:0582227089
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
biological_process
GO:0007420
brain development
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
GOC:dph
GOC:jid
GOC:tb
UBERON:0000955
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
GO:0016280
Wikipedia:Aging
ageing
biological_process
GO:0007568
aging
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
GOC:PO_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
response to nutrients
nutritional response pathway
biological_process
GO:0007584
response to nutrient
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
GOC:go_curators
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
Wikipedia:Excretion
biological_process
GO:0007588
excretion
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
ISBN:0192801023
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
Wikipedia:Coagulation
blood clotting
biological_process
GO:0007596
blood coagulation
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
ISBN:0198506732
http://www.graylab.ac.uk/omd/
The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
Wikipedia:Hemostasis
biological_process
GO:0007599
hemostasis
The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
ISBN:0198506732
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
Wikipedia:Perception
biological_process
GO:0007600
sensory perception
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GOC:ai
GOC:dph
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
Wikipedia:Visual_perception
sense of sight
sensory visual perception
vision
biological_process
GO:0007601
visual perception
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
GOC:ai
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
Wikipedia:Visual_phototransduction
phototransduction, visible light, light adaptation
phototrophin mediated phototransduction
biological_process
opsin
GO:0007602
phototransduction
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
GOC:go_curators
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
visual cascade
visual transduction
biological_process
GO:0007603
phototransduction, visible light
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
GOC:go_curators
ISBN:0198506732
visual cascade
PMID:1962207
PMID:9822721
visual transduction
PMID:10611962
The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.
phototransduction, UV light
phototransduction, UV radiation
phototransduction, ultraviolet light
phototransduction, ultraviolet radiation
biological_process
UV-sensitive opsin
GO:0007604
phototransduction, UV
The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.
GOC:go_curators
ISBN:0198506732
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
Wikipedia:Hearing_(sense)
hearing
perception of sound
biological_process
GO:0007605
sensory perception of sound
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
GOC:ai
The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
chemosensory perception
biological_process
GO:0007606
sensory perception of chemical stimulus
The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GOC:ai
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
Wikipedia:Olfaction
olfaction
scent perception
sense of smell
smell perception
biological_process
GO:0007608
sensory perception of smell
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
GOC:ai
The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.
janelomax
2012-09-20T14:06:08Z
GO:0023032
GO:0044708
GO:0044709
Wikipedia:Behavior
behavioral response to stimulus
behaviour
behavioural response to stimulus
biological_process
single-organism behavior
GO:0007610
1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.
2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).
behavior
The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.
GOC:ems
GOC:jl
ISBN:0395448956
PMID:20160973
The acquisition and processing of information and/or the storage and retrieval of this information over time.
biological_process
GO:0007611
learning or memory
The acquisition and processing of information and/or the storage and retrieval of this information over time.
GOC:jid
PMID:8938125
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
Wikipedia:Learning
biological_process
GO:0007612
learning
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
ISBN:0582227089
ISBN:0721662544
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
Wikipedia:Memory
biological_process
GO:0007613
memory
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
GOC:curators
ISBN:0582227089
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
Wikipedia:Short-term_memory
biological_process
GO:0007614
short-term memory
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
ISBN:0582227089
http://hebb.mit.edu/courses/9.03/lecture4.html
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
Wikipedia:Long-term_memory
biological_process
GO:0007616
long-term memory
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
ISBN:0582227089
http://hebb.mit.edu/courses/9.03/lecture4.html
The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
Wikipedia:Mating_behaviour
mating behaviour
biological_process
GO:0007617
mating behavior
The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
GOC:ai
GOC:dph
The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.
biological_process
GO:0007618
mating
The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.
GOC:jl
ISBN:0387520546
The act of sexual union between male and female, involving the transfer of sperm.
biological_process
GO:0007620
copulation
The act of sexual union between male and female, involving the transfer of sperm.
ISBN:0721662544
The specific behavior of an organism that recur with measured regularity.
rhythmic behavioral response to stimulus
rhythmic behaviour
rhythmic behavioural response to stimulus
biological_process
GO:0007622
rhythmic behavior
The specific behavior of an organism that recur with measured regularity.
GOC:jl
GOC:pr
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
GO:0050895
Wikipedia:Circadian_rhythm
circadian process
biological_process
circadian response
response to circadian rhythm
GO:0007623
circadian rhythm
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
GOC:bf
GOC:go_curators
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
behavior via locomotion
locomotion in response to stimulus
locomotory behavioral response to stimulus
locomotory behaviour
locomotory behavioural response to stimulus
biological_process
GO:0007626
locomotory behavior
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
GOC:dph
Behavior associated with the intake of food.
https://github.com/geneontology/go-ontology/issues/18547
janelomax
2011-10-27T03:53:33Z
GO:0044366
GO:0044367
GO:0044368
GO:0044369
GO:0044370
GO:0044371
GO:0044372
Wikipedia:List_of_feeding_behaviours
behavioral response to food
behavioural response to food
feeding behaviour
eating
feeding from phloem of other organism
feeding from plant phloem
feeding from tissue of other organism
feeding from vascular tissue of another organism
feeding from xylem of other organism
feeding on blood of other organism
feeding on or from other organism
feeding on plant sap
hematophagy
injection of substance into other organism during feeding on blood of other organism
taking of blood meal
biological_process
GO:0007631
See also the biological process term 'behavior ; GO:0007610'.
feeding behavior
Behavior associated with the intake of food.
GOC:mah
The behavior of an organism in response to a visual stimulus.
behavioral response to visual stimulus
behavioural response to visual stimulus
visual behaviour
biological_process
GO:0007632
visual behavior
The behavior of an organism in response to a visual stimulus.
GOC:jid
GOC:pr
Behavior that is dependent upon the sensation of chemicals.
behavioral response to chemical stimulus
behavioural response to chemical stimulus
chemosensory behaviour
biological_process
GO:0007635
chemosensory behavior
Behavior that is dependent upon the sensation of chemicals.
GOC:go_curators
Any process in which a protein is transported to, or maintained in, a specific location.
GO:0008105
protein localisation
biological_process
asymmetric protein localisation
asymmetric protein localization
establishment and maintenance of asymmetric protein localization
establishment and maintenance of protein localization
GO:0008104
protein localization
Any process in which a protein is transported to, or maintained in, a specific location.
GOC:ai
protein localisation
GOC:mah
asymmetric protein localisation
GOC:mah
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
TF binding
molecular_function
GO:0008134
transcription factor binding
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
ISBN:0198506732
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
janelomax
2012-09-19T15:05:24Z
GO:0000004
GO:0007582
GO:0044699
Wikipedia:Biological_process
biological process
physiological process
biological_process
single organism process
single-organism process
GO:0008150
Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this.
biological_process
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GOC:pdt
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
janelomax
2012-10-17T15:46:40Z
GO:0044236
GO:0044710
MIPS_funcat:01
Wikipedia:Metabolism
metabolism
metabolic process resulting in cell growth
metabolism resulting in cell growth
multicellular organism metabolic process
biological_process
single-organism metabolic process
GO:0008152
Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GOC:go_curators
ISBN:0198547684
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
biological_process
accidental cell death
necrosis
GO:0008219
This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.
cell death
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GOC:mah
GOC:mtg_apoptosis
PMID:25236395
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
EC:3.4
Reactome:R-HSA-205112
Reactome:R-HSA-3000243
Reactome:R-HSA-3139027
Reactome:R-HSA-376149
Reactome:R-HSA-448678
Reactome:R-HSA-5655483
Reactome:R-HSA-5684864
Reactome:R-HSA-5685902
Reactome:R-HSA-5693319
hydrolase, acting on peptide bonds
peptide hydrolase activity
protease activity
proteinase activity
molecular_function
GO:0008233
peptidase activity
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GOC:jl
ISBN:0815332181
Reactome:R-HSA-205112
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6
Reactome:R-HSA-3000243
Unknown protease degrades GIF:Cbl to release Cbl
Reactome:R-HSA-3139027
Maturation of HIV Virion
Reactome:R-HSA-376149
Proteolytic processing of SLIT
Reactome:R-HSA-448678
CTSG cleaves CASP1(1-404)
Reactome:R-HSA-5655483
USP1 autocleavage
Reactome:R-HSA-5684864
NAPSA, CTSH, PGA3-5 cleave pro-SFTPB
Reactome:R-HSA-5685902
NAPSA, CTSH, PGA3-5 cleave pro-SFTPC
Reactome:R-HSA-5693319
CTRC hydrolyses PRSS1
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0004220
Reactome:R-HSA-2022381
Reactome:R-HSA-2467775
Reactome:R-HSA-2467809
Reactome:R-HSA-5660752
cysteine protease activity
thiol protease activity
molecular_function
GO:0008234
cysteine-type peptidase activity
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GOC:mah
http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE
Reactome:R-HSA-2022381
Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)
Reactome:R-HSA-2467775
Autocleavage of ESPL1 (Separase)
Reactome:R-HSA-2467809
ESPL1 (Separase) cleaves centromeric cohesin
Reactome:R-HSA-5660752
USP9X deubiquitinates Ub-SNCA
Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
regulation of G protein coupled receptor protein signaling pathway
regulation of G protein coupled receptor protein signalling pathway
regulation of G-protein coupled receptor protein signaling pathway
regulation of G-protein coupled receptor protein signalling pathway
regulation of G-protein-coupled receptor protein signalling pathway
regulation of GPCR protein signaling pathway
regulation of GPCR protein signalling pathway
biological_process
GO:0008277
regulation of G protein-coupled receptor signaling pathway
Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
GOC:go_curators
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
biological_process
cell proliferation
GO:0008283
This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.
cell population proliferation
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
GOC:mah
GOC:mb
Any process that activates or increases the rate or extent of cell proliferation.
up regulation of cell proliferation
up-regulation of cell proliferation
upregulation of cell proliferation
activation of cell proliferation
stimulation of cell proliferation
biological_process
positive regulation of cell proliferation
GO:0008284
positive regulation of cell population proliferation
Any process that activates or increases the rate or extent of cell proliferation.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
down regulation of cell proliferation
down-regulation of cell proliferation
downregulation of cell proliferation
inhibition of cell proliferation
biological_process
negative regulation of cell proliferation
GO:0008285
negative regulation of cell population proliferation
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
GOC:go_curators
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
DNA bending activity
DNA bending involving DNA binding
molecular_function
GO:0008301
DNA binding, bending
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GOC:krc
GOC:vw
PMID:10710711
PMID:19037758
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
Wikipedia:Learning#Associative_learning
Pavlovian conditioning
classical conditioning
conditional learning
conditional response
biological_process
GO:0008306
associative learning
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
ISBN:0582227089
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
biological_process
GO:0008355
olfactory learning
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
ISBN:0582227089
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
Wikipedia:Asymmetric_cell_division
asymmetrical cell division
biological_process
asymmetric cytokinesis
asymmetrical cytokinesis
GO:0008356
asymmetric cell division
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
PMID:11672519
Enables the transfer of a negatively charged ion from one side of a membrane to the other.
Reactome:R-HSA-166214
anion transporter activity
molecular_function
GO:0008509
anion transmembrane transporter activity
Enables the transfer of a negatively charged ion from one side of a membrane to the other.
GOC:dgf
GOC:mtg_transport
ISBN:0815340729
Reactome:R-HSA-166214
FA anion flip-flops to the opposite surface
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
Reactome:R-HSA-2142859
molecular_function
GO:0008514
organic anion transmembrane transporter activity
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GOC:ai
Reactome:R-HSA-2142859
Growing HA is extruded from the cell by ABCC5
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Reactome:R-HSA-200646
Reactome:R-HSA-200652
Reactome:R-HSA-200680
Reactome:R-HSA-200720
Reactome:R-HSA-200729
folate transmembrane transporter activity
folate transporter activity
vitamin B9 transporter activity
vitamin M transporter activity
molecular_function
folic acid transporter activity
GO:0008517
folic acid transmembrane transporter activity
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GOC:ai
Reactome:R-HSA-200646
Cytosolic folate export across the plasma membrane
Reactome:R-HSA-200652
Extracellular 5-methyltetrahydrofolate import across the plasma membrane
Reactome:R-HSA-200680
Cytosolic tetrahydrofolate import across the inner mitochondrial membrane
Reactome:R-HSA-200720
Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane
Reactome:R-HSA-200729
Extracellular folate import across the plasma membrane
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
biological_process
spatial learning
GO:0008542
visual learning
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
GOC:jid
ISBN:0582227089
Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
https://github.com/geneontology/go-ontology/issues/14208
GO:0008642
small protein activating enzyme activity
molecular_function
GO:0008641
ubiquitin-like modifier activating enzyme activity
Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
GOC:jl
GOC:mah
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
janelomax
2012-10-17T15:52:35Z
GO:0044243
GO:0044712
Wikipedia:Catabolism
breakdown
catabolism
degradation
multicellular organismal catabolic process
biological_process
single-organism catabolic process
GO:0009056
catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
ISBN:0198547684
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
janelomax
2012-10-17T15:52:18Z
GO:0044274
GO:0044711
formation
Wikipedia:Anabolism
anabolism
biosynthesis
synthesis
multicellular organismal biosynthetic process
biological_process
single-organism biosynthetic process
GO:0009058
biosynthetic process
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GOC:curators
ISBN:0198547684
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043284
biopolymer biosynthetic process
macromolecule anabolism
macromolecule biosynthesis
macromolecule formation
macromolecule synthesis
biological_process
GO:0009059
macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:mah
biopolymer biosynthetic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
glycoprotein metabolism
biological_process
GO:0009100
glycoprotein metabolic process
The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
glycoprotein anabolism
glycoprotein biosynthesis
glycoprotein formation
glycoprotein synthesis
biological_process
GO:0009101
glycoprotein biosynthetic process
The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
nucleoside metabolism
biological_process
GO:0009116
nucleoside metabolic process
The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
GOC:ma
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
nucleotide metabolism
biological_process
GO:0009117
nucleotide metabolic process
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
GOC:ma
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
regulation of nucleoside metabolism
biological_process
GO:0009118
regulation of nucleoside metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GOC:go_curators
The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
ribonucleoside metabolism
biological_process
GO:0009119
ribonucleoside metabolic process
The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GOC:jl
The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
nucleoside monophosphate metabolism
biological_process
GO:0009123
nucleoside monophosphate metabolic process
The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
nucleoside monophosphate anabolism
nucleoside monophosphate biosynthesis
nucleoside monophosphate formation
nucleoside monophosphate synthesis
biological_process
GO:0009124
nucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
purine nucleoside monophosphate metabolism
biological_process
GO:0009126
purine nucleoside monophosphate metabolic process
The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
purine nucleoside monophosphate anabolism
purine nucleoside monophosphate biosynthesis
purine nucleoside monophosphate formation
purine nucleoside monophosphate synthesis
biological_process
GO:0009127
purine nucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
nucleoside triphosphate metabolism
biological_process
GO:0009141
nucleoside triphosphate metabolic process
The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
nucleoside triphosphate anabolism
nucleoside triphosphate biosynthesis
nucleoside triphosphate formation
nucleoside triphosphate synthesis
biological_process
GO:0009142
nucleoside triphosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
purine nucleoside triphosphate metabolism
biological_process
GO:0009144
purine nucleoside triphosphate metabolic process
The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
purine nucleoside triphosphate anabolism
purine nucleoside triphosphate biosynthesis
purine nucleoside triphosphate formation
purine nucleoside triphosphate synthesis
biological_process
GO:0009145
purine nucleoside triphosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
purine ribonucleotide metabolism
biological_process
GO:0009150
purine ribonucleotide metabolic process
The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
purine ribonucleotide anabolism
purine ribonucleotide biosynthesis
purine ribonucleotide formation
purine ribonucleotide synthesis
biological_process
GO:0009152
purine ribonucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
ribonucleoside monophosphate anabolism
ribonucleoside monophosphate biosynthesis
ribonucleoside monophosphate formation
ribonucleoside monophosphate synthesis
biological_process
GO:0009156
ribonucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
ribonucleoside monophosphate metabolism
biological_process
GO:0009161
ribonucleoside monophosphate metabolic process
The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
nucleoside anabolism
nucleoside biosynthesis
nucleoside formation
nucleoside synthesis
biological_process
GO:0009163
nucleoside biosynthetic process
The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GOC:jl
ISBN:0140512713
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
nucleotide anabolism
nucleotide biosynthesis
nucleotide formation
nucleotide synthesis
biological_process
GO:0009165
nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
GOC:go_curators
The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
purine ribonucleoside monophosphate metabolism
biological_process
GO:0009167
purine ribonucleoside monophosphate metabolic process
The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
purine ribonucleoside monophosphate anabolism
purine ribonucleoside monophosphate biosynthesis
purine ribonucleoside monophosphate formation
purine ribonucleoside monophosphate synthesis
biological_process
GO:0009168
purine ribonucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
ribonucleoside triphosphate metabolism
biological_process
GO:0009199
ribonucleoside triphosphate metabolic process
The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
ribonucleoside triphosphate anabolism
ribonucleoside triphosphate biosynthesis
ribonucleoside triphosphate formation
ribonucleoside triphosphate synthesis
biological_process
GO:0009201
ribonucleoside triphosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
purine ribonucleoside triphosphate metabolism
biological_process
GO:0009205
purine ribonucleoside triphosphate metabolic process
The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
purine ribonucleoside triphosphate anabolism
purine ribonucleoside triphosphate biosynthesis
purine ribonucleoside triphosphate formation
purine ribonucleoside triphosphate synthesis
biological_process
GO:0009206
purine ribonucleoside triphosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
cobalamin metabolism
vitamin B12 metabolic process
vitamin B12 metabolism
vitamin B12 reduction
biological_process
GO:0009235
cobalamin metabolic process
The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GOC:go_curators
The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009121
ribonucleotide metabolism
biological_process
GO:0009259
ribonucleotide metabolic process
The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
ribonucleotide anabolism
ribonucleotide biosynthesis
ribonucleotide formation
ribonucleotide synthesis
biological_process
GO:0009260
ribonucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GOC:go_curators
ISBN:0198506732
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
response to thermal stimulus
biological_process
GO:0009266
response to temperature stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
GOC:hb
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
biological_process
GO:0009267
cellular response to starvation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
biological_process
GO:0009268
response to pH
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GOC:jl
Wikipedia:PH
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
chitin- and beta-glucan-containing cell wall
cellular_component
beta-glucan-containing cell wall
chitin-containing cell wall
GO:0009277
fungal-type cell wall
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
GOC:mcc
GOC:mtg_sensu
ISBN:3540601864
PMID:11283274
PMID:16927300
PMID:3319422
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
outer membrane of cell
cellular_component
GO:0009279
To annotate the plasma (cytoplasmic) membrane, see instead GO:0005886.
cell outer membrane
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
GOC:md
GOC:mtg_sensu
ISBN:0135712254
The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
Wikipedia:Nucleoid
cellular_component
GO:0009295
nucleoid
The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
GOC:bm
GOC:ma
ISBN:3540076689
The controlled release of proteins from a cell.
GO:0045166
GO:0045731
glycoprotein secretion
protein secretion during cell fate commitment
protein secretion resulting in cell fate commitment
biological_process
GO:0009306
protein secretion
The controlled release of proteins from a cell.
GOC:ai
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
response to electromagnetic radiation stimulus
response to radiation stimulus
biological_process
GO:0009314
Note that 'radiation' refers to electromagnetic radiation of any wavelength.
response to radiation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
GOC:jl
Wikipedia:Electromagnetic_radiation
The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.
GO:0010699
GO:0060247
Wikipedia:Quorum_sensing
quorum sensing system
biological_process
cell-cell signaling involved in quorum sensing
detection of cell density by secreted molecule
GO:0009372
quorum sensing
The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.
GOC:krc
GOC:mlg
PMID:10607620
PMID:15716452
PMID:16497924
PMID:16630813
PMID:8288518
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0006951
response to heat shock
biological_process
GO:0009408
response to heat
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GOC:lr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
biological_process
freezing tolerance
GO:0009409
response to cold
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
GOC:lr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
GO:0017104
biological_process
GO:0009410
response to xenobiotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
response to UV light stimulus
response to UV radiation stimulus
response to ultraviolet light stimulus
response to ultraviolet radiation stimulus
biological_process
GO:0009411
response to UV
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
response to dehydration
response to drought
response to thirst
biological_process
drought tolerance
GO:0009414
response to water deprivation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
GOC:lr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
response to water stimulus
biological_process
GO:0009415
response to water
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
GOC:jl
response to water stimulus
GOC:dos
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
biological_process
GO:0009416
response to light stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
GOC:go_curators
ISBN:0582227089
The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.
energytaxis
taxis in response to energy source
biological_process
GO:0009453
energy taxis
The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.
GOC:jl
PMID:11029423
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
Wikipedia:Chloroplast
cellular_component
GO:0009507
chloroplast
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
ISBN:0471245208
The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
cellular_component
GO:0009526
plastid envelope
The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GOC:jy
The proteinaceous ground substance of plastids.
cellular_component
GO:0009532
plastid stroma
The proteinaceous ground substance of plastids.
ISBN:0943088399
Unstacked thylakoids that connect the grana stacks through the stroma.
cellular_component
GO:0009533
chloroplast stromal thylakoid
Unstacked thylakoids that connect the grana stacks through the stroma.
ISBN:0943088399
Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.
cellular_component
GO:0009534
chloroplast thylakoid
Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.
GOC:mtg_sensu
ISBN:0943088399
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
Wikipedia:Plastid
cellular_component
GO:0009536
plastid
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GOC:jl
ISBN:0198547684
The precursor of other plastids.
cellular_component
GO:0009537
proplastid
The precursor of other plastids.
ISBN:0943088399
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
Wikipedia:Fertilisation
syngamy
biological_process
GO:0009566
fertilization
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GOC:tb
ISBN:0198506732
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
cellular_component
GO:0009570
chloroplast stroma
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
ISBN:0198547684
The space enclosed by the double membrane of a proplastid.
cellular_component
GO:0009571
proplastid stroma
The space enclosed by the double membrane of a proplastid.
GOC:jl
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
Wikipedia:Thylakoid
cellular_component
photosynthetic membrane
GO:0009579
A thylakoid is not considered an organelle, but some thylakoids are part of organelles.
thylakoid
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
GOC:ds
GOC:mtg_sensu
ISBN:0198506732
The series of events in which an external stimulus is received by a cell and converted into a molecular signal.
biological_process
perception of external stimulus
GO:0009581
detection of external stimulus
The series of events in which an external stimulus is received by a cell and converted into a molecular signal.
GOC:hb
The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.
biological_process
perception of abiotic stimulus
GO:0009582
detection of abiotic stimulus
The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.
GOC:hb
The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
detection of light
biological_process
perception of light
GO:0009583
detection of light stimulus
The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
GOC:go_curators
The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
biological_process
perception of visible light
GO:0009584
detection of visible light
The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
GOC:go_curators
ISBN:0198506732
The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
detection of UV light stimulus
detection of UV radiation stimulus
detection of ultraviolet light stimulus
detection of ultraviolet radiation stimulus
biological_process
perception of UV
GO:0009589
detection of UV
The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GOC:dos
GOC:go_curators
GOC:hb
ISBN:0198506732
The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.
GO:0009596
biological_process
perception of biotic stimulus
GO:0009595
detection of biotic stimulus
The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to environmental stimulus
biological_process
GO:0009605
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to external stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
response to biotic stress
biological_process
GO:0009607
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to biotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GO:0002245
physiological response to wounding
biological_process
GO:0009611
response to wounding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
response to viruses
biological_process
GO:0009615
response to virus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
https://github.com/geneontology/go-ontology/issues/16572
response to abiotic stress
biological_process
GO:0009628
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to abiotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
detoxification response
biological_process
toxin resistance
toxin susceptibility/resistance
GO:0009636
response to toxic substance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GOC:lr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
response to blue light stimulus
biological_process
GO:0009637
response to blue light
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
GOC:ai
GOC:mtg_far_red
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
biological_process
GO:0009639
response to red or far red light
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:ai
GOC:mtg_far_red
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
biological_process
GO:0009642
response to light intensity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
biological_process
GO:0009644
response to high light intensity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
biological_process
GO:0009645
response to low light intensity stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
GOC:go_curators
GOC:mtg_far_red
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
biological_process
response to darkness
GO:0009646
response to absence of light
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
response to ionic osmotic stress
salinity response
biological_process
GO:0009651
response to salt stress
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GOC:jl
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
embryogenesis and morphogenesis
Wikipedia:Morphogenesis
anatomical structure organization
morphogenesis
biological_process
GO:0009653
anatomical structure morphogenesis
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
GOC:go_curators
ISBN:0521436125
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
biological_process
GO:0009719
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to endogenous stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GOC:sm
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
response to hormone stimulus
biological_process
growth regulator
GO:0009725
response to hormone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
GOC:jl
response to hormone stimulus
GOC:dos
A series of molecular signals mediated by the detection of a hormone.
hormone mediated signalling
biological_process
GO:0009755
hormone-mediated signaling pathway
A series of molecular signals mediated by the detection of a hormone.
GOC:sm
The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
blue light signalling pathway
biological_process
GO:0009785
blue light signaling pathway
The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
GOC:lr
GOC:sm
Any process that modulates the frequency, rate or extent of asymmetric cell division.
biological_process
GO:0009786
regulation of asymmetric cell division
Any process that modulates the frequency, rate or extent of asymmetric cell division.
GOC:lr
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GO:0009795
embryogenesis and morphogenesis
Wikipedia:Embryogenesis
embryogenesis
embryonal development
biological_process
GO:0009790
embryo development
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GOC:go_curators
GOC:isa_complete
GOC:mtg_sensu
The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.
Wikipedia:Pollination
biological_process
GO:0009856
pollination
The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.
GOC:tb
PMID:10973091
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
histogenesis and organogenesis
biological_process
GO:0009887
animal organ morphogenesis
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GOC:dgh
GOC:go_curators
ISBN:0471245208
ISBN:0721662544
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
histogenesis and organogenesis
Wikipedia:Histogenesis
histogenesis
biological_process
GO:0009888
tissue development
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
ISBN:0471245208
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
regulation of anabolism
regulation of biosynthesis
regulation of formation
regulation of synthesis
biological_process
GO:0009889
regulation of biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
down regulation of biosynthetic process
down-regulation of biosynthetic process
downregulation of biosynthetic process
negative regulation of anabolism
negative regulation of biosynthesis
negative regulation of formation
negative regulation of synthesis
inhibition of biosynthetic process
biological_process
GO:0009890
negative regulation of biosynthetic process
Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
positive regulation of anabolism
positive regulation of biosynthesis
positive regulation of formation
positive regulation of synthesis
up regulation of biosynthetic process
up-regulation of biosynthetic process
upregulation of biosynthetic process
activation of biosynthetic process
stimulation of biosynthetic process
biological_process
GO:0009891
positive regulation of biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044252
down regulation of metabolic process
down-regulation of metabolic process
downregulation of metabolic process
negative regulation of metabolism
negative regulation of organismal metabolism
inhibition of metabolic process
inhibition of organismal metabolic process
negative regulation of multicellular organismal metabolic process
biological_process
GO:0009892
negative regulation of metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044253
positive regulation of metabolism
up regulation of metabolic process
up-regulation of metabolic process
upregulation of metabolic process
activation of metabolic process
positive regulation of multicellular organismal metabolic process
positive regulation of organismal metabolism
stimulation of metabolic process
stimulation of organismal metabolic process
up-regulation of organismal metabolic process
biological_process
GO:0009893
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
regulation of breakdown
regulation of catabolism
regulation of degradation
biological_process
GO:0009894
regulation of catabolic process
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
down regulation of catabolic process
down-regulation of catabolic process
downregulation of catabolic process
negative regulation of breakdown
negative regulation of catabolism
negative regulation of degradation
inhibition of catabolic process
biological_process
GO:0009895
negative regulation of catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
positive regulation of breakdown
positive regulation of catabolism
positive regulation of degradation
up regulation of catabolic process
up-regulation of catabolic process
upregulation of catabolic process
activation of catabolic process
stimulation of catabolic process
biological_process
GO:0009896
positive regulation of catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
cellular_component
GO:0009941
chloroplast envelope
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GOC:tb
Any process that modulates the frequency, rate or extent of signal transduction.
GO:0035466
biological_process
regulation of signaling pathway
regulation of signalling pathway
GO:0009966
regulation of signal transduction
Any process that modulates the frequency, rate or extent of signal transduction.
GOC:sm
regulation of signalling pathway
GOC:mah
Any process that activates or increases the frequency, rate or extent of signal transduction.
GO:0035468
up regulation of signal transduction
up-regulation of signal transduction
upregulation of signal transduction
activation of signal transduction
stimulation of signal transduction
biological_process
positive regulation of signaling pathway
positive regulation of signalling pathway
GO:0009967
positive regulation of signal transduction
Any process that activates or increases the frequency, rate or extent of signal transduction.
GOC:sm
positive regulation of signalling pathway
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GO:0035467
down regulation of signal transduction
down-regulation of signal transduction
downregulation of signal transduction
inhibition of signal transduction
biological_process
negative regulation of signaling pathway
negative regulation of signalling pathway
GO:0009968
negative regulation of signal transduction
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GOC:sm
negative regulation of signalling pathway
GOC:mah
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
janelomax
2012-12-11T16:56:55Z
GO:0008151
GO:0044763
GO:0050875
cell physiology
cellular physiological process
cell growth and/or maintenance
biological_process
single-organism cellular process
GO:0009987
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:go_curators
GOC:isa_complete
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
biological_process
GO:0009991
response to extracellular stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
GOC:go_curators
The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
oocyte cell differentiation
biological_process
GO:0009994
oocyte differentiation
The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
GOC:go_curators
GOC:mtg_sensu
The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
phytochrome signaling pathway
red or far red light signaling pathway
red or far-red light signal transduction
red or far-red light signalling pathway
red/far red light signaling pathway
biological_process
GO:0010017
red or far-red light signaling pathway
The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:lr
GOC:mtg_far_red
GOC:sm
red or far red light signaling pathway
GOC:bf
GOC:tb
red or far-red light signal transduction
GOC:signaling
The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
far red light signalling pathway
far red signaling pathway
far-red light signal transduction
biological_process
GO:0010018
far-red light signaling pathway
The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:lr
GOC:mtg_far_red
GOC:sm
far red signaling pathway
GOC:tb
far-red light signal transduction
GOC:signaling
Compaction of chromatin structure prior to meiosis in eukaryotic cells.
chromosome condensation involved in meiotic cell cycle
biological_process
GO:0010032
meiotic chromosome condensation
Compaction of chromatin structure prior to meiosis in eukaryotic cells.
PMID:10072401
chromosome condensation involved in meiotic cell cycle
GOC:dph
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GO:1990367
process resulting in tolerance to organic substance
biological_process
GO:0010033
response to organic substance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GOC:sm
PMID:23356676
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
biological_process
GO:0010035
response to inorganic substance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
GOC:sm
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
response to metal
response to heavy metal
biological_process
heavy metal sensitivity/resistance
GO:0010038
response to metal ion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
GOC:sm
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
response to red light stimulus
biological_process
GO:0010114
response to red light
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mtg_far_red
GOC:sm
The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
red light phototransduction
red light signal transduction
red light signalling pathway
biological_process
GO:0010161
red light signaling pathway
The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mtg_far_red
GOC:sm
red light phototransduction
GOC:signaling
red light signal transduction
GOC:signaling
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
response to X-ray radiation stimulus
biological_process
GO:0010165
response to X-ray
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
GOC:sm
Wikipedia:X-ray
Any process that modulates the frequency, rate or extent of cellular defense response.
regulation of cellular defence response
biological_process
GO:0010185
regulation of cellular defense response
Any process that modulates the frequency, rate or extent of cellular defense response.
GOC:sm
Any process that activates or increases the frequency, rate or extent of cellular defense response.
positive regulation of cellular defence response
up regulation of cellular defense response
up-regulation of cellular defense response
upregulation of cellular defense response
activation of cellular defense response
stimulation of cellular defense response
biological_process
GO:0010186
positive regulation of cellular defense response
Any process that activates or increases the frequency, rate or extent of cellular defense response.
GOC:sm
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
response to ionising radiation
response to ionizing radiation stimulus
biological_process
GO:0010212
response to ionizing radiation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
PMID:12509526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
response to far red light stimulus
biological_process
GO:0010218
response to far red light
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mtg_far_red
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
response to UV-B light stimulus
response to UV-B radiation stimulus
response to UVB light stimulus
response to UVB radiation stimulus
response to medium wave ultraviolet light stimulus
response to medium wave ultraviolet radiation stimulus
biological_process
GO:0010224
response to UV-B
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
response to UV-C light stimulus
response to UV-C radiation stimulus
response to UVC light stimulus
response to UVC radiation stimulus
response to germicidal ultraviolet light stimulus
response to germicidal ultraviolet radiation stimulus
response to shortwave ultraviolet light stimulus
response to shortwave ultraviolet radiation stimulus
biological_process
GO:0010225
response to UV-C
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
biological_process
GO:0010226
response to lithium ion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
response to organic nitrogen
biological_process
GO:0010243
response to organonitrogen compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
PMID:9869419
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
endomembrane organization
endomembrane system organisation
biological_process
GO:0010256
endomembrane system organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
GOC:mah
GOC:sm
endomembrane system organisation
GOC:mah
The infolding of a membrane.
jl
2013-12-02T13:58:34Z
GO:1902534
biological_process
single-organism membrane invagination
GO:0010324
membrane invagination
The infolding of a membrane.
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
biological_process
response to gamma ray
response to gamma-ray photon
GO:0010332
response to gamma radiation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
GOC:tair_curators
Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
biological_process
GO:0010466
negative regulation of peptidase activity
Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
Wikipedia:Gene_expression
biological_process
GO:0010467
gene expression
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
Wikipedia:Regulation_of_gene_expression
regulation of protein expression
biological_process
regulation of gene product expression
GO:0010468
This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.
regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
regulation of receptor activity
biological_process
GO:0010469
regulation of signaling receptor activity
Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
GO:0010506
regulation of autophagy
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
GO:0010507
negative regulation of autophagy
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
GO:0010508
positive regulation of autophagy
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
biological_process
GO:0010543
regulation of platelet activation
Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GOC:BHF
GOC:dph
GOC:tb
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
biological_process
GO:0010544
negative regulation of platelet activation
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GOC:BHF
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0010556
regulation of macromolecule biosynthetic process
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0010557
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0010558
negative regulation of macromolecule biosynthetic process
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
biological_process
GO:0010559
regulation of glycoprotein biosynthetic process
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GOC:dph
GOC:tb
Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
biological_process
GO:0010560
positive regulation of glycoprotein biosynthetic process
Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
biological_process
GO:0010561
negative regulation of glycoprotein biosynthetic process
Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
biological_process
GO:0010562
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
biological_process
GO:0010563
negative regulation of phosphorus metabolic process
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GOC:dph
GOC:tb
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
biological_process
GO:0010564
regulation of cell cycle process
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
biological_process
GO:0010572
positive regulation of platelet activation
Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GOC:dph
GOC:sl
GOC:tb
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0010604
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0010605
negative regulation of macromolecule metabolic process
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
biological_process
GO:0010608
posttranscriptional regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
GOC:dph
GOC:tb
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
developmental programmed cell death
programmed cell death involved in development
biological_process
GO:0010623
This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.
programmed cell death involved in cell development
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
GOC:dph
GOC:mtg_apoptosis
GOC:tb
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
biological_process
GO:0010628
positive regulation of gene expression
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
biological_process
GO:0010629
This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.
negative regulation of gene expression
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
positive regulation of organelle organisation
biological_process
positive regulation of organelle organization and biogenesis
GO:0010638
positive regulation of organelle organization
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:dph
GOC:tb
positive regulation of organelle organisation
GOC:mah
positive regulation of organelle organization and biogenesis
GOC:mah
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
negative regulation of organelle organisation
biological_process
negative regulation of organelle organization and biogenesis
GO:0010639
negative regulation of organelle organization
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:dph
GOC:tb
negative regulation of organelle organisation
GOC:mah
negative regulation of organelle organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
GO:0010646
regulation of cell communication
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
GO:0010647
positive regulation of cell communication
Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
GO:0010648
negative regulation of cell communication
Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
mah
2012-04-20T02:45:12Z
GO:1900401
regulation of transcription from RNA polymerase II promoter, meiotic
regulation of meiosis by regulation of transcription from RNA polymerase II promoter
biological_process
GO:0010672
regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GOC:dph
GOC:tb
PMID:12161753
regulation of transcription from RNA polymerase II promoter, meiotic
GOC:mah
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
dianna.fisk
2012-05-01T08:40:11Z
GO:1900476
positive regulation of transcription from RNA polymerase II promoter, meiotic
activation of meiosis by positive regulation of transcription from RNA polymerase II promoter
positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
biological_process
GO:0010673
positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GOC:dph
GOC:tb
PMID:8618927
positive regulation of transcription from RNA polymerase II promoter, meiotic
GOC:mah
activation of meiosis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
dianna.fisk
2012-05-01T08:39:58Z
GO:1900475
negative regulation of transcription from RNA polymerase II promoter, meiotic
activation of meiosis by negative regulation of transcription from RNA polymerase II promoter
positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
biological_process
GO:0010674
negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GOC:dph
GOC:tb
PMID:8618927
negative regulation of transcription from RNA polymerase II promoter, meiotic
GOC:mah
activation of meiosis by negative regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
GO:0010720
positive regulation of cell development
Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:BHF
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
GO:0010721
negative regulation of cell development
Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:BHF
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
biological_process
GO:0010767
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
biological_process
GO:0010768
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
regulation of mitochondrion organisation
biological_process
GO:0010821
regulation of mitochondrion organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
regulation of mitochondrion organisation
GOC:mah
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
positive regulation of mitochondrion organisation
biological_process
GO:0010822
positive regulation of mitochondrion organization
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
positive regulation of mitochondrion organisation
GOC:mah
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
negative regulation of mitochondrion organisation
biological_process
GO:0010823
negative regulation of mitochondrion organization
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
negative regulation of mitochondrion organisation
GOC:mah
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
biological_process
GO:0010927
cellular component assembly involved in morphogenesis
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
GOC:dph
GOC:tb
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
biological_process
GO:0010941
regulation of cell death
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:dph
GOC:tb
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
biological_process
GO:0010942
positive regulation of cell death
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
tanyaberardini
2009-04-27T09:53:22Z
biological_process
GO:0010948
negative regulation of cell cycle process
Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
tanyaberardini
2009-04-27T11:54:32Z
biological_process
GO:0010952
positive regulation of peptidase activity
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
tanyaberardini
2009-05-06T11:47:17Z
biological_process
GO:0010960
magnesium ion homeostasis
Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
GOC:dph
GOC:tb
The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
tanyaberardini
2009-05-27T10:56:08Z
microtubule-based transport
establishment of localization by movement along microtubule
movement along microtubule
biological_process
GO:0010970
transport along microtubule
The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
GOC:dph
GOC:mah
GOC:tb
establishment of localization by movement along microtubule
GOC:dph
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
tanyaberardini
2009-06-01T10:44:45Z
regulation of neurite biosynthesis
regulation of neurite development
regulation of neurite formation
regulation of neurite growth
biological_process
GO:0010975
regulation of neuron projection development
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GOC:dph
GOC:tb
regulation of neurite biosynthesis
GOC:mah
regulation of neurite development
GOC:mah
regulation of neurite formation
GOC:mah
regulation of neurite growth
GOC:mah
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
tanyaberardini
2009-06-01T10:46:44Z
positive regulation of neurite biosynthesis
positive regulation of neurite development
positive regulation of neurite formation
positive regulation of neurite growth
biological_process
GO:0010976
positive regulation of neuron projection development
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GOC:dph
GOC:tb
positive regulation of neurite biosynthesis
GOC:mah
positive regulation of neurite development
GOC:mah
positive regulation of neurite formation
GOC:mah
positive regulation of neurite growth
GOC:mah
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
tanyaberardini
2009-06-01T10:47:42Z
negative regulation of neurite biosynthesis
negative regulation of neurite development
negative regulation of neurite formation
negative regulation of neurite growth
biological_process
growth cone collapse
GO:0010977
negative regulation of neuron projection development
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GOC:dph
GOC:tb
negative regulation of neurite biosynthesis
GOC:mah
negative regulation of neurite development
GOC:mah
negative regulation of neurite formation
GOC:mah
negative regulation of neurite growth
GOC:mah
growth cone collapse
GOC:pr
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0016244
regulated cell death
Wikipedia:Programmed_cell_death
caspase-independent cell death
non-apoptotic programmed cell death
nonapoptotic programmed cell death
biological_process
PCD
RCD
caspase-independent apoptosis
GO:0012501
Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.
programmed cell death
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GOC:lr
GOC:mtg_apoptosis
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
Wikipedia:Endomembrane_system
cellular_component
GO:0012505
endomembrane system
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GOC:lh
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
NIF_Subcellular:sao1153182838
cellular_component
GO:0012506
vesicle membrane
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
GOC:mah
GOC:vesicle
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
GO:0030664
COPII coated vesicle membrane
ER to Golgi constitutive secretory pathway transport vesicle membrane
ER-Golgi transport vesicle membrane
endoplasmic reticulum to Golgi transport vesicle membrane
endoplasmic reticulum-Golgi transport vesicle membrane
cellular_component
GO:0012507
ER to Golgi transport vesicle membrane
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
GOC:ai
GOC:ascb_2009
GOC:dph
GOC:tb
A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
GO:0009520
Wikipedia:Oil_body
oil body
oilbody
oleosome
spherosome
cellular_component
GO:0012511
monolayer-surrounded lipid storage body
A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
GOC:mtg_sensu
ISBN:0943088372
Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.
biological_process
GO:0014041
regulation of neuron maturation
Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.
GOC:ef
Any process that activates or increases the frequency, rate or extent of neuron maturation.
up regulation of neuron maturation
up-regulation of neuron maturation
upregulation of neuron maturation
activation of neuron maturation
stimulation of neuron maturation
biological_process
GO:0014042
positive regulation of neuron maturation
Any process that activates or increases the frequency, rate or extent of neuron maturation.
GOC:ef
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
down regulation of neuron maturation
down-regulation of neuron maturation
downregulation of neuron maturation
inhibition of neuron maturation
biological_process
GO:0014043
negative regulation of neuron maturation
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
GOC:ef
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
paola
2013-07-02T09:44:28Z
GO:0097481
GO:0097483
NIF_Subcellular:sao1196688972
Wikipedia:Postsynaptic_density
neuronal postsynaptic density
post synaptic density
post-synaptic density
postsynaptic density of dendrite
cellular_component
GO:0014069
postsynaptic density
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GOC:BHF
GOC:dos
GOC:ef
GOC:jid
GOC:pr
GOC:sjp
PMID:14532281
Wikipedia:Postsynaptic_density
http://molneuro.kaist.ac.kr/psd
neuronal postsynaptic density
GO:0097481
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
response to organic cyclic substance
biological_process
GO:0014070
response to organic cyclic compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
GOC:ef
response to organic cyclic substance
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
biological_process
GO:0014072
response to isoquinoline alkaloid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
GOC:ef
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
response to amine stimulus
biological_process
GO:0014075
response to amine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
GOC:ef
response to amine stimulus
GOC:dos
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015831
enzyme transport
biological_process
GO:0015031
protein transport
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Enables the transfer of an ion from one side of a membrane to the other.
ion transporter activity
molecular_function
GO:0015075
ion transmembrane transporter activity
Enables the transfer of an ion from one side of a membrane to the other.
GOC:dgf
GOC:mtg_transport
ISBN:0815340729
true
Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.
https://github.com/geneontology/go-ontology/issues/14372
inorganic solute uptake transmembrane transporter activity
inorganic uptake permease activity
molecular_function
GO:0015318
inorganic molecular entity transmembrane transporter activity
Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.
GOC:mtg_transport
ISBN:0815340729
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
cellular_component
GO:0015630
microtubule cytoskeleton
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
GOC:jl
ISBN:0395825172
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
biological_process
GO:0015711
organic anion transport
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GOC:ai
GOC:krc
The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0015833
peptide transport
The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0015849
organic acid transport
The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ISBN:0198506732
The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
folate transport
vitamin B9 transport
vitamin M transport
biological_process
GO:0015884
folic acid transport
The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GOC:ai
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0015893
drug transport
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0006770
pantothenate metabolism
vitamin B5 metabolic process
vitamin B5 metabolism
biological_process
GO:0015939
pantothenate metabolic process
The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GOC:ai
ISBN:0721662544
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
Wikipedia:Biological_membrane
cellular_component
GO:0016020
membrane
membrane
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GOC:dos
GOC:mah
ISBN:0815316194
true
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0044235
GO:0071842
MIPS_funcat:42
cell organisation
cellular component organisation at cellular level
cellular component organisation in other organism
cellular component organization at cellular level
cellular component organization in other organism
biological_process
cell organization and biogenesis
GO:0016043
cellular component organization
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GOC:ai
GOC:jl
GOC:mah
cellular component organisation at cellular level
GOC:mah
cellular component organisation in other organism
GOC:mah
cell organization and biogenesis
GOC:mah
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
GO:0048591
cellular growth
growth of cell
biological_process
cell expansion
metabolic process resulting in cell growth
metabolism resulting in cell growth
non-developmental cell growth
non-developmental growth of a unicellular organism
GO:0016049
cell growth
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
GOC:ai
non-developmental cell growth
GOC:mah
non-developmental growth of a unicellular organism
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
vesicle organisation
biological_process
vesicle organization and biogenesis
GO:0016050
vesicle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
GOC:mah
vesicle organization and biogenesis
GOC:mah
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
GO:0009586
rhodopsin mediated phototransduction
rhodopsin mediated signalling pathway
rhodopsin signaling
biological_process
GO:0016056
rhodopsin mediated signaling pathway
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
GOC:bf
GOC:dph
GOC:hb
GOC:signaling
GOC:tb
rhodopsin mediated phototransduction
GOC:bf
rhodopsin mediated signalling pathway
GOC:dph
GOC:tb
rhodopsin signaling
GOC:bf
An immune response mediated by immunoglobulins, whether cell-bound or in solution.
antibody-mediated immune response
biological_process
GO:0016064
immunoglobulin mediated immune response
An immune response mediated by immunoglobulins, whether cell-bound or in solution.
GOC:add
GO_REF:0000022
ISBN:0781735149
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA metabolism
biological_process
GO:0016070
RNA metabolic process
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
ISBN:0198506732
The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.
diterpenoid metabolism
diterpene metabolic process
diterpene metabolism
biological_process
GO:0016101
diterpenoid metabolic process
The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.
ISBN:0198547684
The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.
carotene metabolism
biological_process
GO:0016119
carotene metabolic process
The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.
ISBN:0198547684
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006899
vesicle transport
vesicular transport
nonselective vesicle transport
biological_process
protein sorting along secretory pathway
vesicle trafficking
GO:0016192
vesicle-mediated transport
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GOC:ai
GOC:mah
ISBN:08789310662000
vesicular transport
GOC:mah
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
GO:0034262
autophagy
biological_process
GO:0016236
Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618). As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities.
macroautophagy
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
PMID:11099404
PMID:12914914
PMID:15798367
PMID:16973210
PMID:20159618
PMID:9412464
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
positive regulation of starvation-induced autophagy
up regulation of macroautophagy
up-regulation of macroautophagy
upregulation of macroautophagy
activation of macroautophagy
stimulation of macroautophagy
biological_process
GO:0016239
positive regulation of macroautophagy
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
GOC:go_curators
PMID:9412464
positive regulation of starvation-induced autophagy
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of macroautophagy.
regulation of starvation-induced autophagy
biological_process
GO:0016241
regulation of macroautophagy
Any process that modulates the frequency, rate or extent of macroautophagy.
GOC:krc
regulation of starvation-induced autophagy
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
down regulation of macroautophagy
down-regulation of macroautophagy
downregulation of macroautophagy
negative regulation of starvation-induced autophagy
inhibition of macroautophagy
biological_process
GO:0016242
negative regulation of macroautophagy
Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
GOC:go_curators
negative regulation of starvation-induced autophagy
GOC:ascb_2009
GOC:dph
GOC:tb
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
Wikipedia:RNA_interference
RNAi
posttranscriptional gene silencing by siRNA
biological_process
GO:0016246
Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'.
RNA interference
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
GOC:ems
PMID:11201747
PMID:11713190
PMID:18771919
posttranscriptional gene silencing by siRNA
GOC:mah
true
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
Reactome:R-HSA-6788855
Reactome:R-HSA-6788867
phosphokinase activity
molecular_function
GO:0016301
Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.
kinase activity
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
ISBN:0198506732
Reactome:R-HSA-6788855
FN3KRP phosphorylates PsiAm, RibAm
Reactome:R-HSA-6788867
FN3K phosphorylates ketosamines
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
Wikipedia:Phosphorylation
biological_process
GO:0016310
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
ISBN:0198506732
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
biological_process
GO:0016321
female meiosis chromosome segregation
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
GOC:ai
The inactivation of gene expression by a posttranscriptional mechanism.
Wikipedia:Post_transcriptional_gene_silencing
PTGS
post-transcriptional gene silencing
quelling
biological_process
cosuppression
GO:0016441
posttranscriptional gene silencing
The inactivation of gene expression by a posttranscriptional mechanism.
GOC:mah
PMID:15020054
post-transcriptional gene silencing
GOC:vw
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
Wikipedia:Gene_silencing
long-term maintenance of gene inactivation
biological_process
GO:0016458
This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class.
gene silencing
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
GOC:dos
GOC:dph
GOC:jid
GOC:tb
The directed movement of substances or organelles within the cytosol.
biological_process
GO:0016482
cytosolic transport
The directed movement of substances or organelles within the cytosol.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
down regulation of angiogenesis
down-regulation of angiogenesis
downregulation of angiogenesis
inhibition of angiogenesis
biological_process
GO:0016525
negative regulation of angiogenesis
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
GOC:go_curators
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
EC:2
Reactome:R-HSA-1483089
Reactome:R-HSA-1483186
Reactome:R-HSA-5668414
Reactome:R-HSA-6787403
Reactome:R-HSA-8868783
molecular_function
GO:0016740
transferase activity
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
ISBN:0198506732
Reactome:R-HSA-1483089
PE is converted to PS by PTDSS2
Reactome:R-HSA-1483186
PC is converted to PS by PTDSS1
Reactome:R-HSA-5668414
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK
Reactome:R-HSA-6787403
GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA
Reactome:R-HSA-8868783
TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
EC:2.7
molecular_function
GO:0016772
Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
transferase activity, transferring phosphorus-containing groups
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
EC:3
Reactome:R-HSA-1236938
Reactome:R-HSA-2029475
Reactome:R-HSA-5694583
Reactome:R-HSA-5695964
Reactome:R-HSA-6786190
Reactome:R-HSA-6788295
Reactome:R-HSA-8938314
Reactome:R-HSA-8952137
molecular_function
GO:0016787
hydrolase activity
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
ISBN:0198506732
Reactome:R-HSA-1236938
Partial proteolysis of antigen in phagolysosomes
Reactome:R-HSA-2029475
Production of AA by iPLA2 upon FCGR activation
Reactome:R-HSA-5694583
ABHD4 hydrolyses NAPE
Reactome:R-HSA-5695964
ABHD14B hydrolyses PNPB
Reactome:R-HSA-6786190
CMBL hydrolyses OM to OLMS
Reactome:R-HSA-6788295
HDHD1:Mg2+ dephosphorylates PURIDP
Reactome:R-HSA-8938314
ENPPs hydrolyse CoA-SH to PPANT, PAP
Reactome:R-HSA-8952137
Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6
synthetase activity
molecular_function
GO:0016874
ligase activity
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6
GOC:mah
synthetase activity
GOC:jh2
Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6.2
ligase activity, forming carbon-sulphur bonds
molecular_function
GO:0016877
ligase activity, forming carbon-sulfur bonds
Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6.2
GOC:mah
Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6.3
other carbon-nitrogen ligase activity
molecular_function
GO:0016879
ligase activity, forming carbon-nitrogen bonds
Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GOC:mah
Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6.3.2
peptide synthase activity
molecular_function
GO:0016881
acid-amino acid ligase activity
Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GOC:jl
GOC:mah
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
ligand-dependent nuclear receptor binding
molecular_function
ligand-dependent nuclear receptor interactor activity
GO:0016922
nuclear receptor binding
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
GOC:mah
PMID:7776974
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
Wikipedia:Drug_metabolism
drug metabolism
biological_process
GO:0017144
drug metabolic process
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
GOC:cab2
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
stem cell renewal
biological_process
GO:0017145
stem cell division
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
GOC:jid
ISBN:0582227089
The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
heterocycle anabolism
heterocycle biosynthesis
heterocycle formation
heterocycle synthesis
biological_process
GO:0018130
heterocycle biosynthetic process
The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
ISBN:0198547684
Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.
Wikipedia:Host_(biology)
host organism
cellular_component
GO:0018995
host cellular component
Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.
ISBN:0198506732
The specific behavior of an organism that is associated with reproduction.
janelomax
2012-09-19T16:01:37Z
GO:0033057
GO:0044704
reproductive behavior in a multicellular organism
reproductive behaviour
multicellular organism reproductive behavior
biological_process
single-organism reproductive behavior
GO:0019098
reproductive behavior
The specific behavior of an organism that is associated with reproduction.
GOC:jl
GOC:pr
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
regulation of lipid metabolism
biological_process
GO:0019216
regulation of lipid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
biological_process
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0019219
regulation of nucleobase-containing compound metabolic process
Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
regulation of phosphate metabolism
biological_process
GO:0019220
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044246
regulation of metabolism
regulation of multicellular organismal metabolic process
regulation of organismal metabolic process
biological_process
GO:0019222
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
regulation of organismal metabolic process
GOC:tb
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
Wikipedia:Nociception
nociception
perception of physiological pain
biological_process
GO:0019233
sensory perception of pain
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
GOC:curators
The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
aromatic compound anabolism
aromatic compound biosynthesis
aromatic compound formation
aromatic compound synthesis
aromatic hydrocarbon biosynthesis
aromatic hydrocarbon biosynthetic process
biological_process
GO:0019438
aromatic compound biosynthetic process
The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
GOC:ai
The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0006411
GO:0044268
Wikipedia:Protein_metabolism
protein metabolic process and modification
protein metabolism
protein metabolism and modification
multicellular organismal protein metabolic process
biological_process
GO:0019538
protein metabolic process
The chemical reactions and pathways involving a protein. Includes protein modification.
GOC:ma
The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
organophosphate metabolism
biological_process
GO:0019637
organophosphate metabolic process
The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
ISBN:0198506732
The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.
ribose phosphate metabolism
biological_process
GO:0019693
ribose phosphate metabolic process
The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.
GOC:ai
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
B lymphocyte mediated immune effector process
B lymphocyte mediated immunity
B-cell mediated immune effector process
B-cell mediated immunity
B-lymphocyte mediated immune effector process
B-lymphocyte mediated immunity
biological_process
GO:0019724
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
GOC:add
GO_REF:0000022
ISBN:0781735149
Any process involved in the maintenance of an internal steady state at the level of the cell.
biological_process
GO:0019725
cellular homeostasis
Any process involved in the maintenance of an internal steady state at the level of the cell.
GOC:isa_complete
GOC:jl
ISBN:0395825172
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.
regulation of isoprenoid metabolism
biological_process
GO:0019747
regulation of isoprenoid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.
GOC:go_curators
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
carboxylic acid metabolism
biological_process
GO:0019752
carboxylic acid metabolic process
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
ISBN:0198506732
Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.
Reactome:R-HSA-5681999
APG12 conjugating enzyme activity
APG12 ligase activity
Atg12 conjugating enzyme activity
Atg12 ligase activity
molecular_function
GO:0019777
Atg12 transferase activity
Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.
GOC:mah
PMID:12826404
Reactome:R-HSA-5681999
ATG10 transfers ATG12 from ATG7 to ATG10
Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
molecular_function
APG12 activating enzyme activity
GO:0019778
Atg12 activating enzyme activity
Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
GOC:mah
APG12 activating enzyme activity
GOC:vw
Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.
GO:1904454
GO:1904455
small conjugating protein-specific protease activity
ubiquitin-like specific protease activity
ubiquitin-like-protein-specific protease activity
ubiquitin-specific protease activity involved in negative regulation of ERAD pathway
ubiquitin-specific protease activity involved in positive regulation of ERAD pathway
molecular_function
GO:0019783
ubiquitin-like protein-specific protease activity
Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.
GOC:ma
GOC:mah
small conjugating protein-specific protease activity
GOC:dph
Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
molecular_function
APG8-PE hydrolase
APG8-specific protease activity
GO:0019786
Atg8-specific protease activity
Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
GOC:mah
APG8-specific protease activity
GOC:vw
Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
GO:0008639
GO:0008640
Reactome:R-HSA-5678490
Reactome:R-HSA-688137
small conjugating protein transferase activity
small conjugating protein ligase activity
small protein conjugating enzyme activity
ubiquitin-like conjugating enzyme activity
ubiquitin-like-protein ligase activity
molecular_function
E2
E3
GO:0019787
small conjugating protein ligase activity
ubiquitin-like protein transferase activity
Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
GOC:mah
GOC:rn
PMID:10806345
PMID:10884686
Reactome:R-HSA-5678490
ATG16L1 complex transfers LC3 from ATG3 to PE
Reactome:R-HSA-688137
RIP2 is K63 polyubiquitinated
small conjugating protein transferase activity
GOC:dph
small conjugating protein ligase activity
GOC:dph
E3
dph:GOC
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
cellular_component
GO:0019867
outer membrane
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
GOC:go_curators
A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
Wikipedia:Sexual_reproduction
biological_process
GO:0019953
Sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.
sexual reproduction
A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
GOC:jl
GOC:kmv
GOC:krc
GOC:tb
ISBN:0387520546
Wikipedia:Sexual_reproduction
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
Wikipedia:Asexual_reproduction
biological_process
parthenogenesis
GO:0019954
asexual reproduction
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
ISBN:0387520546
parthenogenesis
Wikipedia:Parthenogenesis
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
biological_process
GO:0021700
developmental maturation
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
GOC:cls
GOC:dgh
GOC:dph
GOC:jid
GO_REF:0000021
Generation of cells within the nervous system.
Wikipedia:Neurogenesis
nervous system cell generation
biological_process
neural cell differentiation
GO:0022008
neurogenesis
Generation of cells within the nervous system.
GOC:cls
GOC:curators
GOC:dgh
GOC:dph
GOC:jid
GO_REF:0000021
nervous system cell generation
neural cell differentiation
GOC:BHF
GOC:dph
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
regulation of rhodopsin mediated signalling
biological_process
GO:0022400
regulation of rhodopsin mediated signaling pathway
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
GOC:mah
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
biological_process
GO:0022402
cell cycle process
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GOC:isa_complete
GOC:mtg_cell_cycle
One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
biological_process
GO:0022403
cell cycle phase
One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GOC:mtg_cell_cycle
The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
membrane docking
biological_process
GO:0022406
membrane docking
The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
GOC:isa_complete
PMID:27875684
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
biological_process
GO:0022407
regulation of cell-cell adhesion
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
GOC:isa_complete
Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
down regulation of cell-cell adhesion
down-regulation of cell-cell adhesion
downregulation of cell-cell adhesion
inhibition of cell-cell adhesion
biological_process
GO:0022408
negative regulation of cell-cell adhesion
Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
GOC:isa_complete
Any process that activates or increases the rate or extent of cell adhesion to another cell.
up regulation of cell-cell adhesion
up-regulation of cell-cell adhesion
upregulation of cell-cell adhesion
activation of cell-cell adhesion
stimulation of cell-cell adhesion
biological_process
GO:0022409
positive regulation of cell-cell adhesion
Any process that activates or increases the rate or extent of cell adhesion to another cell.
GOC:isa_complete
A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
biological_process
GO:0022410
circadian sleep/wake cycle process
A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
GOC:isa_complete
A cellular process that results in the breakdown of a cellular component.
GO:0071845
cell structure disassembly
cellular component disassembly at cellular level
biological_process
GO:0022411
cellular component disassembly
A cellular process that results in the breakdown of a cellular component.
GOC:isa_complete
A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.
reproductive cellular process in multicellular organism
biological_process
GO:0022412
cellular process involved in reproduction in multicellular organism
A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.
GOC:isa_complete
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
janelomax
2012-09-19T15:56:06Z
GO:0044702
biological_process
single organism reproductive process
GO:0022414
reproductive process
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GOC:dph
GOC:isa_complete
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
regulation of morphogenesis
biological_process
GO:0022603
regulation of anatomical structure morphogenesis
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
GOC:mah
The aggregation, arrangement and bonding together of a cellular component.
GO:0071844
cell structure assembly
cellular component assembly at cellular level
biological_process
GO:0022607
cellular component assembly
The aggregation, arrangement and bonding together of a cellular component.
GOC:isa_complete
The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
biological_process
GO:0022610
biological adhesion
The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
GOC:isa_complete
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0005386
GO:0015563
GO:0015646
GO:0022891
GO:0022892
Reactome:R-HSA-1236947
Reactome:R-HSA-429036
Reactome:R-HSA-5638209
Reactome:R-HSA-5671707
Reactome:R-HSA-6784434
Reactome:R-HSA-6784436
molecular_function
substrate-specific transmembrane transporter activity
substrate-specific transporter activity
uptake permease activity
uptake transmembrane transporter activity
GO:0022857
transmembrane transporter activity
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GOC:jid
GOC:mtg_transport
ISBN:0815340729
Reactome:R-HSA-1236947
Egress of internalized antigen to the cytosol via sec61
Reactome:R-HSA-429036
SLC2A9 transports Fru, Glc, urate
Reactome:R-HSA-5638209
Defective SLC2A9 does not transport Fru, Glc, urate
Reactome:R-HSA-5671707
Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA
Reactome:R-HSA-6784434
An unknown carrier transports cytosolic glyoxylate to the peroxisome
Reactome:R-HSA-6784436
An unknown carrier transports mitochondrial glyoxylate to the cytosol
Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
biological_process
GO:0022898
regulation of transmembrane transporter activity
Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
GOC:dph
GOC:mtg_cardio
GOC:mtg_transport
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
2010-02-16T09:30:50Z
biological_process
signal transduction via phosphorylation event
signal transmission via phosphorylation event
GO:0023014
signal transduction by protein phosphorylation
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
GOC:mtg_signal
GOC:signaling
signal transduction via phosphorylation event
GOC:bf
signal transmission via phosphorylation event
GOC:bf
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
2010-02-16T09:30:50Z
biological_process
regulation of gene expression as a consequence of signal transmission
GO:0023019
signal transduction involved in regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
GOC:mtg_signal
regulation of gene expression as a consequence of signal transmission
GOC:bf
Any process that modulates the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
biological_process
regulation of signaling process
regulation of signalling process
GO:0023051
regulation of signaling
Any process that modulates the frequency, rate or extent of a signaling process.
GOC:mtg_signal
regulation of signaling process
GOC:bf
regulation of signalling process
GOC:mah
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
janelomax
2010-02-16T09:30:50Z
GO:0023046
GO:0044700
biological signaling
signaling process
signalling
biological_process
signalling process
single organism signaling
GO:0023052
Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.
signaling
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GOC:mtg_signal
GOC:mtg_signaling_feb11
GOC:signaling
signalling process
GOC:mah
Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
positive regulation of signalling process
biological_process
positive regulation of signaling process
GO:0023056
positive regulation of signaling
Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
GOC:mtg_signal
positive regulation of signalling process
GOC:mah
positive regulation of signaling process
GOC:bf
Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
biological_process
negative regulation of signaling process
negative regulation of signalling process
GO:0023057
negative regulation of signaling
Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
GOC:mtg_signal
negative regulation of signaling process
GOC:bf
negative regulation of signalling process
GOC:mah
The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
2010-02-16T09:30:50Z
signal secretion
biological_process
GO:0023061
signal release
The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
GOC:mtg_signal
signal secretion
GOC:bf
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
biological_process
GO:0030003
cellular cation homeostasis
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
GOC:ceb
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell projection organisation
biological_process
cell projection organization and biogenesis
cell surface structure organization and biogenesis
GO:0030030
cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
GOC:mah
http://www.cogsci.princeton.edu/~wn/
cell projection organization and biogenesis
GOC:mah
cell surface structure organization and biogenesis
GOC:mah
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
formation of a cell surface projection
biological_process
cell projection biogenesis
GO:0030031
cell projection assembly
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
GOC:mah
http://www.cogsci.princeton.edu/~wn/
cell projection biogenesis
GOC:mah
A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
Wikipedia:Cell_junction
cellular_component
GO:0030054
cell junction
A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
GOC:aruk
GOC:bc
GOC:mah
ISBN:0198506732
PMID:26820516
PMID:28096264
http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html
A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.
plasma membrane-derived thylakoid
cellular_component
GO:0030075
bacterial thylakoid
A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.
GOC:mah
GOC:mtg_sensu
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
Wikipedia:Haematopoiesis
blood cell biosynthesis
blood cell formation
haemopoiesis
hematopoiesis
biological_process
GO:0030097
hemopoiesis
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
GOC:dgh
ISBN:0198506732
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
biological_process
GO:0030099
myeloid cell differentiation
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
GOC:add
ISBN:0781735149
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
NK cell activation
biological_process
GO:0030101
natural killer cell activation
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
GOC:mgi_curators
ISBN:0781735149
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
NIF_Subcellular:sao885490876
constitutive secretory pathway transport vesicle
Golgi to vacuole transport vesicle
Golgi-vacuole transport vesicle
cellular_component
secretory vesicle
GO:0030133
Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.
transport vesicle
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
GOC:mah
PMID:22160157
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
pg
2017-06-22T16:26:57Z
GO:0030138
GO:0140045
COPII-associated ER to Golgi transport vesicle
COPII-associated vesicle
COPII-coated vesicle
cellular_component
COPII vesicle
ER to Golgi constitutive secretory pathway transport vesicle
ER to Golgi transport vesicle
ER-Golgi transport vesicle
endoplasmic reticulum to Golgi transport vesicle
endoplasmic reticulum-Golgi transport vesicle
GO:0030134
COPII-coated ER to Golgi transport vesicle
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
PMID:11252894
PMID:17499046
PMID:22160157
PMID:8004676
Wikipedia:COPII
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
GO:0005909
NIF_Subcellular:sao1985096626
cellular_component
GO:0030135
coated vesicle
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
ISBN:0815316194
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
secretory vesicle
cellular_component
GO:0030141
Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.
secretory granule
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
GOC:mah
ISBN:0198506732
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
Wikipedia:Cellular_differentiation
biological_process
GO:0030154
cell differentiation
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
ISBN:0198506732
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
biological_process
cell adhesion receptor regulator activity
GO:0030155
regulation of cell adhesion
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
GOC:mah
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
regulation of peptidolysis
biological_process
GO:0030162
regulation of proteolysis
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:mah
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
blood coagulation, platelet activation
biological_process
GO:0030168
platelet activation
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
http://www.graylab.ac.uk/omd/
blood coagulation, platelet activation
GOC:add
GOC:pde
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
biological_process
GO:0030182
neuron differentiation
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
GOC:mah
Any process that modulates the frequency, rate or extent of blood coagulation.
biological_process
GO:0030193
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
GOC:mah
Any process that activates or increases the frequency, rate or extent of blood coagulation.
up regulation of blood coagulation
up-regulation of blood coagulation
upregulation of blood coagulation
activation of blood coagulation
stimulation of blood coagulation
biological_process
GO:0030194
positive regulation of blood coagulation
Any process that activates or increases the frequency, rate or extent of blood coagulation.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
down regulation of blood coagulation
down-regulation of blood coagulation
downregulation of blood coagulation
inhibition of blood coagulation
biological_process
GO:0030195
negative regulation of blood coagulation
Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
extracellular matrix organisation
biological_process
extracellular matrix organization and biogenesis
GO:0030198
extracellular matrix organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
GOC:mah
extracellular matrix organization and biogenesis
GOC:mah
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
Wikipedia:Erythropoiesis
RBC differentiation
erythrocyte cell differentiation
erythropoiesis
red blood cell differentiation
biological_process
GO:0030218
erythrocyte differentiation
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
GOC:mah
RBC differentiation
CL:0000232
erythropoiesis
GOC:add
GOC:dph
red blood cell differentiation
CL:0000232
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
GO:0000068
DNA condensation
eukaryotic chromosome condensation
nuclear chromosome condensation
biological_process
GO:0030261
chromosome condensation
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
GOC:mah
ISBN:0815316194
DNA condensation
Wikipedia:DNA_condensation
eukaryotic chromosome condensation
GOC:bf
nuclear chromosome condensation
GOC:bf
Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
apoptotic nuclear change
biological_process
GO:0030262
apoptotic nuclear changes
Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
GOC:mah
GOC:mtg_apoptosis
The compaction of chromatin during apoptosis.
Wikipedia:Pyknosis
pyknosis
biological_process
GO:0030263
apoptotic chromosome condensation
The compaction of chromatin during apoptosis.
GOC:mah
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
molecular_function
GO:0030284
For estrogen receptors that function within the nucleus to modulate transcription, consider instead annotating to the child terms 'estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038052' or 'estrogen-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038053'.
estrogen receptor activity
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
GOC:signaling
PMID:17615392
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
up regulation of cell growth
up-regulation of cell growth
upregulation of cell growth
activation of cell growth
stimulation of cell growth
biological_process
GO:0030307
positive regulation of cell growth
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
down regulation of cell growth
down-regulation of cell growth
downregulation of cell growth
inhibition of cell growth
biological_process
GO:0030308
negative regulation of cell growth
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
GOC:go_curators
A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.
cellular_component
GO:0030312
The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.
external encapsulating structure
A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.
GOC:go_curators
An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.
Wikipedia:Cell_envelope
cellular_component
GO:0030313
cell envelope
An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.
GOC:ds
GOC:mlg
http://pathmicro.med.sc.edu/fox/cell_envelope.htm
Any process involved in the controlled movement of a flagellated sperm cell.
sperm motility
sperm movement
Wikipedia:Sperm_motility
flagellated sperm movement
biological_process
GO:0030317
flagellated sperm motility
Any process involved in the controlled movement of a flagellated sperm cell.
GOC:cilia
GOC:jl
GOC:krc
The cytoplasm of a host cell.
paola
2014-12-01T14:14:21Z
GO:0097679
cellular_component
other organism cytoplasm
GO:0030430
host cell cytoplasm
The cytoplasm of a host cell.
GOC:mah
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Wikipedia:Sleep
biological_process
diapause
dormancy
lethargus
GO:0030431
sleep
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
ISBN:0192800981
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
intracellular receptor mediated signaling pathway
intracellular receptor-mediated signaling pathway
intracellular receptor-mediated signalling pathway
biological_process
GO:0030522
intracellular receptor signaling pathway
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
GOC:bf
GOC:mah
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed.
MIPS_funcat:18.02.07
molecular_function
GO:0030545
receptor regulator activity
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed.
GOC:ceb
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.
receptor activator activity
molecular_function
GO:0030546
signaling receptor activator activity
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.
GOC:ceb
The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0051708
intracellular protein transport in other organism during symbiotic interaction
intracellular protein transport in other organism involved in symbiotic interaction
host cell protein transport
intracellular protein transport in host
biological_process
GO:0030581
symbiont intracellular protein transport in host
The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mb
intracellular protein transport in other organism during symbiotic interaction
GOC:dph
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
regulation of vitamin metabolism
biological_process
GO:0030656
regulation of vitamin metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GOC:mah
The lipid bilayer surrounding a transport vesicle.
secretory vesicle membrane
constitutive secretory pathway transport vesicle membrane
cellular_component
GO:0030658
transport vesicle membrane
The lipid bilayer surrounding a transport vesicle.
GOC:mah
The lipid bilayer surrounding a cytoplasmic vesicle.
cellular_component
GO:0030659
cytoplasmic vesicle membrane
The lipid bilayer surrounding a cytoplasmic vesicle.
GOC:mah
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
cellular_component
Golgi vesicle membrane
GO:0030660
Golgi-associated vesicle membrane
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
GOC:mah
The lipid bilayer surrounding a coated vesicle.
cellular_component
GO:0030662
coated vesicle membrane
The lipid bilayer surrounding a coated vesicle.
GOC:mah
The lipid bilayer surrounding a secretory granule.
secretory vesicle membrane
cellular_component
GO:0030667
secretory granule membrane
The lipid bilayer surrounding a secretory granule.
GOC:mah
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
biological_process
GO:0030705
cytoskeleton-dependent intracellular transport
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
GOC:mah
The release of a mature ovum/oocyte from an ovary.
Wikipedia:Ovulation
biological_process
GO:0030728
ovulation
The release of a mature ovum/oocyte from an ovary.
GOC:bf
ISBN:0878932437
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
regulation of nucleotide anabolism
regulation of nucleotide biosynthesis
regulation of nucleotide formation
regulation of nucleotide synthesis
biological_process
GO:0030808
regulation of nucleotide biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
down regulation of nucleotide biosynthetic process
down-regulation of nucleotide biosynthetic process
downregulation of nucleotide biosynthetic process
negative regulation of nucleotide anabolism
negative regulation of nucleotide biosynthesis
negative regulation of nucleotide formation
negative regulation of nucleotide synthesis
inhibition of nucleotide biosynthetic process
biological_process
GO:0030809
negative regulation of nucleotide biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
positive regulation of nucleotide anabolism
positive regulation of nucleotide biosynthesis
positive regulation of nucleotide formation
positive regulation of nucleotide synthesis
up regulation of nucleotide biosynthetic process
up-regulation of nucleotide biosynthetic process
upregulation of nucleotide biosynthetic process
activation of nucleotide biosynthetic process
stimulation of nucleotide biosynthetic process
biological_process
GO:0030810
positive regulation of nucleotide biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GOC:mah
A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
intraflagellar transport complex
intraflagellar transport particle
cellular_component
IFT complex
GO:0030990
Note that we deem cilia and microtubule-based flagella to be equivalent.
intraciliary transport particle
A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
GOC:cilia
GOC:kmv
PMID:14570576
PMID:22118932
PMID:23945166
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
GO:0005578
NIF_Subcellular:nlx_subcell_20090513
Wikipedia:Extracellular_matrix
proteinaceous extracellular matrix
matrisome
cellular_component
GO:0031012
extracellular matrix
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
GOC:BHF
GOC:mah
GOC:rph
NIF_Subcellular:nlx_subcell_20090513
PMID:21123617
PMID:28089324
Any process in which RNA molecules inactivate expression of target genes.
RNA-mediated gene silencing
biological_process
GO:0031047
gene silencing by RNA
Any process in which RNA molecules inactivate expression of target genes.
GOC:dph
GOC:mah
GOC:tb
PMID:15020054
RNA-mediated gene silencing
GOC:dph
GOC:tb
The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate.
biological_process
GO:0031049
programmed DNA elimination
The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate.
GOC:mah
GOC:ns
Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
establishment or maintenance of heterochromatin architecture
biological_process
GO:0031052
Note that this term refers to breakage of chromosomes during normal DNA rearrangements characteristic of ciliates; it is not to be used for DNA damage or other abnormal occurrences.
chromosome breakage
Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
GOC:ns
establishment or maintenance of heterochromatin architecture
GOC:mah
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
NIF_Subcellular:sao830981606
cellular_component
intracellular membrane
GO:0031090
organelle membrane
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
GOC:dos
GOC:mah
intracellular membrane
NIF_Subcellular:sao830981606
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
neurite biosynthesis
neurite development
neurite formation
neurite growth
neurite outgrowth
biological_process
GO:0031175
neuron projection development
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GOC:mah
neurite development
GOC:dph
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.
pseudopodium organisation
biological_process
pseudopodium organization and biogenesis
GO:0031268
pseudopodium organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.
GOC:pg
pseudopodium organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular metabolism
biological_process
GO:0031323
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
down regulation of cellular metabolic process
down-regulation of cellular metabolic process
downregulation of cellular metabolic process
negative regulation of cellular metabolism
inhibition of cellular metabolic process
biological_process
GO:0031324
negative regulation of cellular metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolism
up regulation of cellular metabolic process
up-regulation of cellular metabolic process
upregulation of cellular metabolic process
activation of cellular metabolic process
stimulation of cellular metabolic process
biological_process
GO:0031325
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
regulation of cellular anabolism
regulation of cellular biosynthesis
regulation of cellular formation
regulation of cellular synthesis
biological_process
GO:0031326
regulation of cellular biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
down regulation of cellular biosynthetic process
down-regulation of cellular biosynthetic process
downregulation of cellular biosynthetic process
negative regulation of cellular anabolism
negative regulation of cellular biosynthesis
negative regulation of cellular formation
negative regulation of cellular synthesis
inhibition of cellular biosynthetic process
biological_process
GO:0031327
negative regulation of cellular biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
positive regulation of cellular anabolism
positive regulation of cellular biosynthesis
positive regulation of cellular formation
positive regulation of cellular synthesis
up regulation of cellular biosynthetic process
up-regulation of cellular biosynthetic process
upregulation of cellular biosynthetic process
activation of cellular biosynthetic process
stimulation of cellular biosynthetic process
biological_process
GO:0031328
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
regulation of cellular breakdown
regulation of cellular catabolism
regulation of cellular degradation
biological_process
GO:0031329
regulation of cellular catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
down regulation of cellular catabolic process
down-regulation of cellular catabolic process
downregulation of cellular catabolic process
negative regulation of cellular breakdown
negative regulation of cellular catabolism
negative regulation of cellular degradation
inhibition of cellular catabolic process
biological_process
GO:0031330
negative regulation of cellular catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
positive regulation of cellular breakdown
positive regulation of cellular catabolism
positive regulation of cellular degradation
up regulation of cellular catabolic process
up-regulation of cellular catabolic process
upregulation of cellular catabolic process
activation of cellular catabolic process
stimulation of cellular catabolic process
biological_process
GO:0031331
positive regulation of cellular catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
down regulation of protein complex assembly
down-regulation of protein complex assembly
downregulation of protein complex assembly
inhibition of protein complex assembly
biological_process
negative regulation of protein complex assembly
GO:0031333
negative regulation of protein-containing complex assembly
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
GOC:mah
Any process that activates or increases the frequency, rate or extent of protein complex assembly.
up regulation of protein complex assembly
up-regulation of protein complex assembly
upregulation of protein complex assembly
activation of protein complex assembly
stimulation of protein complex assembly
biological_process
positive regulation of protein complex assembly
GO:0031334
positive regulation of protein-containing complex assembly
Any process that activates or increases the frequency, rate or extent of protein complex assembly.
GOC:mah
Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.
biological_process
GO:0031341
regulation of cell killing
Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
down regulation of cell killing
down-regulation of cell killing
downregulation of cell killing
inhibition of cell killing
biological_process
GO:0031342
negative regulation of cell killing
Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
GOC:mah
Any process that activates or increases the frequency, rate or extent of cell killing.
up regulation of cell killing
up-regulation of cell killing
upregulation of cell killing
activation of cell killing
stimulation of cell killing
biological_process
GO:0031343
positive regulation of cell killing
Any process that activates or increases the frequency, rate or extent of cell killing.
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
regulation of cell projection organisation
biological_process
regulation of cell projection organization and biogenesis
GO:0031344
regulation of cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
regulation of cell projection organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
down regulation of cell projection organization
down-regulation of cell projection organization
downregulation of cell projection organization
negative regulation of cell projection organisation
inhibition of cell projection organization
biological_process
negative regulation of cell projection organization and biogenesis
GO:0031345
negative regulation of cell projection organization
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
down regulation of cell projection organization
GOC:mah
negative regulation of cell projection organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
positive regulation of cell projection organisation
up regulation of cell projection organization
up-regulation of cell projection organization
upregulation of cell projection organization
activation of cell projection organization
stimulation of cell projection organization
biological_process
positive regulation of cell projection organization and biogenesis
GO:0031346
positive regulation of cell projection organization
Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
positive regulation of cell projection organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of a defense response.
biological_process
GO:0031347
regulation of defense response
Any process that modulates the frequency, rate or extent of a defense response.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
down regulation of defense response
down-regulation of defense response
downregulation of defense response
inhibition of defense response
biological_process
GO:0031348
negative regulation of defense response
Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GOC:mah
Any process that activates or increases the frequency, rate or extent of a defense response.
up regulation of defense response
up-regulation of defense response
upregulation of defense response
activation of defense response
stimulation of defense response
biological_process
GO:0031349
positive regulation of defense response
Any process that activates or increases the frequency, rate or extent of a defense response.
GOC:mah
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
biological_process
GO:0031399
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
down regulation of protein modification
down-regulation of protein modification
downregulation of protein modification
inhibition of protein modification
biological_process
GO:0031400
negative regulation of protein modification process
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
up regulation of protein modification
up-regulation of protein modification
upregulation of protein modification
activation of protein modification
stimulation of protein modification
biological_process
GO:0031401
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
A vesicle found in the cytoplasm of a cell.
GO:0016023
NIF_Subcellular:sao180601769
cellular_component
cytoplasmic membrane bounded vesicle
cytoplasmic membrane-enclosed vesicle
cytoplasmic, membrane-bounded vesicle
GO:0031410
cytoplasmic vesicle
A vesicle found in the cytoplasm of a cell.
GOC:ai
GOC:mah
GOC:vesicles
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
biological_process
GO:0031427
response to methotrexate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
GOC:ef
GOC:mah
ISBN:0198506732
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
establishment and maintenance of protein complex localization
protein complex localisation
biological_process
protein complex localization
GO:0031503
protein-containing complex localization
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
GOC:mah
protein complex localisation
GOC:mah
Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0001908
killing of cells of another organism
killing of cells of another, non-host, organism
biological_process
GO:0031640
killing of cells of other organism
Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GOC:add
killing of cells of another organism
GOC:bf
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
regulation of neurological process
regulation of neurological system process
regulation of neurophysiological process
biological_process
GO:0031644
regulation of nervous system process
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
GOC:dph
GOC:mah
GOC:tb
regulation of neurological process
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
down regulation of neurological process
down-regulation of neurological process
downregulation of neurological process
negative regulation of neurological process
negative regulation of neurological system process
negative regulation of neurophysiological process
inhibition of neurological process
biological_process
GO:0031645
negative regulation of nervous system process
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
GOC:dph
GOC:mah
GOC:tb
negative regulation of neurological process
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
positive regulation of neurological process
positive regulation of neurological system process
positive regulation of neurophysiological process
up regulation of neurological process
up-regulation of neurological process
upregulation of neurological process
activation of neurological process
stimulation of neurological process
biological_process
GO:0031646
positive regulation of nervous system process
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
GOC:dph
GOC:mah
GOC:tb
positive regulation of neurological process
GOC:dph
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
biological_process
GO:0031667
response to nutrient levels
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
biological_process
GO:0031668
cellular response to extracellular stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
biological_process
GO:0031669
cellular response to nutrient levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
response to corticosteroid stimulus
biological_process
GO:0031960
response to corticosteroid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
GOC:mah
PMID:11027914
response to corticosteroid stimulus
GOC:dos
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
cellular_component
GO:0031967
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
GOC:mah
GOC:pz
Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
Wikipedia:Chloroplast_membrane
cellular_component
GO:0031969
chloroplast membrane
Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
GOC:mah
GOC:pz
The region between the inner and outer lipid bilayers of an organelle envelope.
organelle intermembrane space
cellular_component
GO:0031970
organelle envelope lumen
The region between the inner and outer lipid bilayers of an organelle envelope.
GOC:mah
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
cellular_component
GO:0031974
membrane-enclosed lumen
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GOC:add
GOC:mah
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
cellular_component
GO:0031975
envelope
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
GOC:mah
GOC:pz
Any thylakoid within a plastid.
cellular_component
GO:0031976
plastid thylakoid
Any thylakoid within a plastid.
GOC:pz
The volume enclosed by the nuclear inner membrane.
cellular_component
GO:0031981
nuclear lumen
The volume enclosed by the nuclear inner membrane.
GOC:mah
GOC:pz
Any small, fluid-filled, spherical organelle enclosed by membrane.
GO:0031988
NIF_Subcellular:sao221389602
Wikipedia:Vesicle_(biology)
cellular_component
membrane-bounded vesicle
membrane-enclosed vesicle
GO:0031982
vesicle
Any small, fluid-filled, spherical organelle enclosed by membrane.
GOC:mah
GOC:pz
GOC:vesicles
A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
suborganelle compartment
cellular_component
GO:0031984
Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles.
organelle subcompartment
A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
GOC:mah
GOC:pz
Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
locomotion during locomotory behaviour
biological_process
GO:0031987
locomotion involved in locomotory behavior
Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GOC:mah
The chemical reactions and pathways involving mitochondrial DNA.
mitochondrial DNA metabolism
mtDNA metabolic process
mtDNA metabolism
biological_process
GO:0032042
mitochondrial DNA metabolic process
The chemical reactions and pathways involving mitochondrial DNA.
GOC:mah
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
blebbing
membrane blebbing
cell blebbing
plasma membrane bleb assembly
plasma membrane blebbing
biological_process
GO:0032060
bleb assembly
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
GOC:mah
GOC:mtg_apoptosis
PMID:12083798
PMID:16624291
Wikipedia:Bleb_(cell_biology)
blebbing
GOC:pr
membrane blebbing
GOC:pr
plasma membrane bleb assembly
GOC:pr
plasma membrane blebbing
GOC:pr
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
down regulation of protein binding
down-regulation of protein binding
downregulation of protein binding
inhibition of protein binding
biological_process
GO:0032091
negative regulation of protein binding
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
GOC:mah
Any process that activates or increases the frequency, rate or extent of protein binding.
up regulation of protein binding
up-regulation of protein binding
upregulation of protein binding
activation of protein binding
stimulation of protein binding
biological_process
GO:0032092
positive regulation of protein binding
Any process that activates or increases the frequency, rate or extent of protein binding.
GOC:mah
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
biological_process
GO:0032101
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
down regulation of response to external stimulus
down-regulation of response to external stimulus
downregulation of response to external stimulus
inhibition of response to external stimulus
biological_process
GO:0032102
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to external stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
GOC:mah
Any process that activates, maintains or increases the rate of a response to an external stimulus.
up regulation of response to external stimulus
up-regulation of response to external stimulus
upregulation of response to external stimulus
activation of response to external stimulus
stimulation of response to external stimulus
biological_process
GO:0032103
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to external stimulus
Any process that activates, maintains or increases the rate of a response to an external stimulus.
GOC:mah
Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.
biological_process
GO:0032104
regulation of response to extracellular stimulus
Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.
down regulation of response to extracellular stimulus
down-regulation of response to extracellular stimulus
downregulation of response to extracellular stimulus
inhibition of response to extracellular stimulus
biological_process
GO:0032105
negative regulation of response to extracellular stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.
GOC:mah
Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.
up regulation of response to extracellular stimulus
up-regulation of response to extracellular stimulus
upregulation of response to extracellular stimulus
activation of response to extracellular stimulus
stimulation of response to extracellular stimulus
biological_process
GO:0032106
positive regulation of response to extracellular stimulus
Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.
GOC:mah
Any process that modulates the frequency, rate or extent of a response to nutrient levels.
biological_process
GO:0032107
regulation of response to nutrient levels
Any process that modulates the frequency, rate or extent of a response to nutrient levels.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.
down regulation of response to nutrient levels
down-regulation of response to nutrient levels
downregulation of response to nutrient levels
inhibition of response to nutrient levels
biological_process
GO:0032108
negative regulation of response to nutrient levels
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.
GOC:mah
Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.
up regulation of response to nutrient levels
up-regulation of response to nutrient levels
upregulation of response to nutrient levels
activation of response to nutrient levels
stimulation of response to nutrient levels
biological_process
GO:0032109
positive regulation of response to nutrient levels
Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.
GOC:mah
The process in which a methyl group is covalently attached to a molecule.
Wikipedia:Methylation
biological_process
GO:0032259
methylation
The process in which a methyl group is covalently attached to a molecule.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
regulation of cellular protein metabolism
biological_process
GO:0032268
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
down regulation of cellular protein metabolic process
down-regulation of cellular protein metabolic process
downregulation of cellular protein metabolic process
negative regulation of cellular protein metabolism
inhibition of cellular protein metabolic process
biological_process
GO:0032269
negative regulation of cellular protein metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolism
up regulation of cellular protein metabolic process
up-regulation of cellular protein metabolic process
upregulation of cellular protein metabolic process
activation of cellular protein metabolic process
stimulation of cellular protein metabolic process
biological_process
GO:0032270
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.
Gray's type I synapse
cellular_component
GO:0032279
asymmetric synapse
A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.
GOC:dgh
GOC:ef
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
biological_process
GO:0032386
regulation of intracellular transport
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
down regulation of intracellular transport
down-regulation of intracellular transport
downregulation of intracellular transport
inhibition of intracellular transport
biological_process
GO:0032387
negative regulation of intracellular transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
up regulation of intracellular transport
up-regulation of intracellular transport
upregulation of intracellular transport
activation of intracellular transport
stimulation of intracellular transport
biological_process
GO:0032388
positive regulation of intracellular transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that modulates the activity of a transporter.
biological_process
GO:0032409
regulation of transporter activity
Any process that modulates the activity of a transporter.
GOC:mah
Any process that stops or reduces the activity of a transporter.
down regulation of transporter activity
down-regulation of transporter activity
downregulation of transporter activity
inhibition of transporter activity
biological_process
GO:0032410
negative regulation of transporter activity
Any process that stops or reduces the activity of a transporter.
GOC:mah
Any process that activates or increases the activity of a transporter.
up regulation of transporter activity
up-regulation of transporter activity
upregulation of transporter activity
activation of transporter activity
stimulation of transporter activity
biological_process
GO:0032411
positive regulation of transporter activity
Any process that activates or increases the activity of a transporter.
GOC:mah
Any process that modulates the activity of an ion transporter.
regulation of ion transporter activity
biological_process
GO:0032412
regulation of ion transmembrane transporter activity
Any process that modulates the activity of an ion transporter.
GOC:mah
GOC:tb
regulation of ion transporter activity
GOC:tb
Any process that stops or reduces the activity of an ion transporter.
down regulation of ion transporter activity
down-regulation of ion transporter activity
downregulation of ion transporter activity
negative regulation of ion transporter activity
inhibition of ion transporter activity
biological_process
GO:0032413
negative regulation of ion transmembrane transporter activity
Any process that stops or reduces the activity of an ion transporter.
GOC:mah
GOC:tb
negative regulation of ion transporter activity
GOC:tb
Any process that activates or increases the activity of an ion transporter.
positive regulation of ion transporter activity
up regulation of ion transporter activity
up-regulation of ion transporter activity
upregulation of ion transporter activity
activation of ion transporter activity
stimulation of ion transporter activity
biological_process
GO:0032414
positive regulation of ion transmembrane transporter activity
Any process that activates or increases the activity of an ion transporter.
GOC:mah
GOC:tb
positive regulation of ion transporter activity
GOC:tb
Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
Golgi calcium ion concentration regulation
calcium ion homeostasis in Golgi
regulation of Golgi calcium ion concentration
regulation of calcium ion concentration in Golgi
biological_process
GO:0032468
Golgi calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
ER calcium ion concentration regulation
ER calcium ion homeostasis
calcium ion homeostasis in ER
calcium ion homeostasis in endoplasmic reticulum
endoplasmic reticulum calcium ion concentration regulation
regulation of ER calcium ion concentration
regulation of calcium ion concentration in ER
regulation of calcium ion concentration in endoplasmic reticulum
regulation of endoplasmic reticulum calcium ion concentration
biological_process
GO:0032469
endoplasmic reticulum calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
GOC:mah
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
janelomax
2012-09-19T16:07:47Z
GO:0044707
GO:0050874
organismal physiological process
biological_process
single-multicellular organism process
GO:0032501
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GOC:curators
GOC:dph
GOC:isa_complete
GOC:tb
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
janelomax
2012-12-19T12:21:31Z
GO:0044767
development
biological_process
single-organism developmental process
GO:0032502
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GOC:isa_complete
The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
biological_process
GO:0032504
multicellular organism reproduction
The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GOC:isa_complete
GOC:jid
The directed movement of a protein from one location to another within a lipid bilayer.
protein translocation within membrane
receptor translocation within membrane
receptor transport within lipid bilayer
biological_process
GO:0032594
protein transport within lipid bilayer
The directed movement of a protein from one location to another within a lipid bilayer.
GOC:mah
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
RNA anabolism
RNA biosynthesis
RNA formation
RNA synthesis
biological_process
GO:0032774
Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.
RNA biosynthetic process
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
GOC:mah
GOC:txnOH
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
monocarboxylate metabolic process
monocarboxylic acid metabolism
biological_process
GO:0032787
monocarboxylic acid metabolic process
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
GOC:vk
Any process that modulates the frequency, rate or extent of natural killer cell activation.
regulation of NK cell activation
biological_process
GO:0032814
regulation of natural killer cell activation
Any process that modulates the frequency, rate or extent of natural killer cell activation.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.
down regulation of natural killer cell activation
down-regulation of natural killer cell activation
downregulation of natural killer cell activation
negative regulation of NK cell activation
inhibition of natural killer cell activation
biological_process
GO:0032815
negative regulation of natural killer cell activation
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.
GOC:mah
Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
positive regulation of NK cell activation
up regulation of natural killer cell activation
up-regulation of natural killer cell activation
upregulation of natural killer cell activation
activation of natural killer cell activation
stimulation of natural killer cell activation
biological_process
GO:0032816
positive regulation of natural killer cell activation
Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
GOC:mah
All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
cellular_component
GO:0032838
plasma membrane bounded cell projection cytoplasm
All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
GOC:krc
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
biological_process
GO:0032870
cellular response to hormone stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
GOC:mah
Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
regulation of localisation
biological_process
GO:0032879
regulation of localization
Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GOC:mah
regulation of localisation
GOC:mah
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
regulation of protein localisation
biological_process
GO:0032880
regulation of protein localization
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
GOC:dph
GOC:mah
GOC:tb
regulation of protein localisation
GOC:mah
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
biological_process
GO:0032886
regulation of microtubule-based process
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
GOC:mah
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.
biological_process
GO:0032887
regulation of spindle elongation
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.
GOC:mah
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
biological_process
GO:0032888
regulation of mitotic spindle elongation
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0032890
regulation of organic acid transport
Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of organic acid transport
down-regulation of organic acid transport
downregulation of organic acid transport
inhibition of organic acid transport
biological_process
GO:0032891
negative regulation of organic acid transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of organic acid transport
up-regulation of organic acid transport
upregulation of organic acid transport
activation of organic acid transport
stimulation of organic acid transport
biological_process
GO:0032892
positive regulation of organic acid transport
Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
The controlled release of a substance by a cell.
Wikipedia:Secretion
cellular secretion
biological_process
GO:0032940
secretion by cell
The controlled release of a substance by a cell.
GOC:mah
The process in which cellular structures, including whole cells or cell parts, are generated and organized.
cellular structure morphogenesis
biological_process
GO:0032989
cellular component morphogenesis
The process in which cellular structures, including whole cells or cell parts, are generated and organized.
GOC:dph
GOC:mah
GOC:tb
cellular structure morphogenesis
GOC:dph
GOC:tb
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0043234
macromolecular complex
macromolecule complex
protein containing complex
protein complex
protein-protein complex
cellular_component
GO:0032991
A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
protein-containing complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GOC:dos
GOC:mah
The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
tetrapyrrole metabolism
biological_process
GO:0033013
tetrapyrrole metabolic process
The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
GOC:mah
Any process in which a macromolecule is transported to, or maintained in, a specific location.
macromolecule localisation
biological_process
GO:0033036
macromolecule localization
Any process in which a macromolecule is transported to, or maintained in, a specific location.
GOC:mah
macromolecule localisation
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
regulation of organelle organisation
biological_process
regulation of organelle organization and biogenesis
GO:0033043
regulation of organelle organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:mah
regulation of organelle organisation
GOC:mah
regulation of organelle organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
regulation of chromosome organisation
biological_process
regulation of chromosome organization and biogenesis
GO:0033044
regulation of chromosome organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
GOC:mah
regulation of chromosome organisation
GOC:mah
regulation of chromosome organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of sister chromatid segregation.
biological_process
GO:0033045
regulation of sister chromatid segregation
Any process that modulates the frequency, rate or extent of sister chromatid segregation.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.
biological_process
GO:0033046
negative regulation of sister chromatid segregation
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.
GOC:mah
Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.
biological_process
GO:0033047
regulation of mitotic sister chromatid segregation
Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.
biological_process
GO:0033048
negative regulation of mitotic sister chromatid segregation
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.
GOC:mah
Interacting selectively and non-covalently with a progesterone receptor.
molecular_function
GO:0033142
progesterone receptor binding
Interacting selectively and non-covalently with a progesterone receptor.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
biological_process
GO:0033157
regulation of intracellular protein transport
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
biological_process
GO:0033273
response to vitamin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
GOC:sl
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
secretory granule organisation
biological_process
secretory granule organization and biogenesis
GO:0033363
secretory granule organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
GOC:mah
secretory granule organisation
GOC:mah
secretory granule organization and biogenesis
GOC:mah
A process in which a protein is transported to, or maintained in, a location within an organelle.
protein localisation to organelle
protein localization in organelle
biological_process
GO:0033365
protein localization to organelle
A process in which a protein is transported to, or maintained in, a location within an organelle.
GOC:mah
protein localisation to organelle
GOC:mah
protein localization in organelle
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
T cell secretory granule organisation
T lymphocyte secretory granule organization
T-cell secretory granule organization
T-lymphocyte secretory granule organization
biological_process
T cell secretory granule organization and biogenesis
T-lymphocyte secretory granule maturation
GO:0033371
T cell secretory granule organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
GOC:mah
T cell secretory granule organisation
GOC:mah
T cell secretory granule organization and biogenesis
GOC:mah
A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.
biological_process
GO:0033500
carbohydrate homeostasis
A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
GO:0033554
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stress
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:mah
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.
protein amino acid glycosylation in cytosol
biological_process
GO:0033576
protein glycosylation in cytosol
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.
GOC:mah
GOC:pr
PMID:12042244
protein amino acid glycosylation in cytosol
GOC:bf
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.
protein amino acid glycosylation in ER
protein amino acid glycosylation in endoplasmic reticulum
biological_process
core glycosylation
GO:0033577
protein glycosylation in endoplasmic reticulum
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.
GOC:mah
GOC:pr
PMID:12042244
protein amino acid glycosylation in endoplasmic reticulum
GOC:bf
core glycosylation
PMID:6345657
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
protein amino acid glycosylation in Golgi
terminal glycosylation
biological_process
GO:0033578
protein glycosylation in Golgi
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
GOC:mah
GOC:pr
PMID:12042244
protein amino acid glycosylation in Golgi
GOC:bf
terminal glycosylation
PMID:6345657
Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
GO:0033635
modulation by symbiont of host response to abiotic stimulus
Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modulation by symbiont of host response to thermal stimulus
biological_process
GO:0033636
modulation by symbiont of host response to temperature stimulus
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
GO:0033640
modulation by symbiont of host response to osmotic stress
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
GO:0033641
modulation by symbiont of host response to pH
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
cellular_component
GO:0033643
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
host cell part
Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell intracellular part
cellular_component
GO:0033646
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
host intracellular part
Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
cellular_component
GO:0033647
host intracellular organelle
Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host intracellular membrane-enclosed organelle
cellular_component
GO:0033648
host intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation by organism of host apoptotic programmed cell death
down-regulation by organism of host apoptotic programmed cell death
downregulation by organism of host apoptotic programmed cell death
inhibition by organism of host apoptotic programmed cell death
negative regulation by symbiont of host apoptosis
biological_process
GO:0033668
Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'.
negative regulation by symbiont of host apoptotic process
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
down regulation of kinase activity
down-regulation of kinase activity
downregulation of kinase activity
inhibition of kinase activity
kinase inhibitor
biological_process
GO:0033673
negative regulation of kinase activity
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:mah
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
up regulation of kinase activity
up-regulation of kinase activity
upregulation of kinase activity
kinase activator
stimulation of kinase activity
biological_process
GO:0033674
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
biological_process
GO:0033993
response to lipid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
GOC:sl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
response to cytokine stimulus
biological_process
GO:0034097
response to cytokine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
GOC:sl
response to cytokine stimulus
GOC:dos
Any process of regulating the production and elimination of erythrocytes within an organism.
RBC homeostasis
red blood cell homeostasis
biological_process
GO:0034101
erythrocyte homeostasis
Any process of regulating the production and elimination of erythrocytes within an organism.
GOC:add
PMID:10694114
PMID:14754397
RBC homeostasis
CL:0000232
red blood cell homeostasis
CL:0000232
The attachment of a cell to a second cell of the identical type via adhesion molecules.
biological_process
GO:0034109
Note that this term is not synonymous with 'homophilic cell adhesion ; GO:0007156'; the process may occur by homophilic or heterophilic mechanisms.
homotypic cell-cell adhesion
The attachment of a cell to a second cell of the identical type via adhesion molecules.
GOC:add
Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
biological_process
GO:0034110
regulation of homotypic cell-cell adhesion
Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.
biological_process
GO:0034111
negative regulation of homotypic cell-cell adhesion
Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.
GOC:add
Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.
biological_process
GO:0034112
positive regulation of homotypic cell-cell adhesion
Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.
GOC:add
A process in which an ion is transported across a membrane.
GO:0099131
ion membrane transport
transmembrane ion transport
ATP hydrolysis coupled ion transmembrane transport
biological_process
GO:0034220
Note that this term is not intended for use in annotating lateral movement within membranes.
ion transmembrane transport
A process in which an ion is transported across a membrane.
GOC:mah
transmembrane ion transport
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
regulation of amide metabolism
biological_process
GO:0034248
regulation of cellular amide metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
negative regulation of amide metabolism
biological_process
GO:0034249
negative regulation of cellular amide metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
positive regulation of amide metabolism
biological_process
GO:0034250
positive regulation of cellular amide metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
GOC:mah
The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
nucleobase, nucleoside and nucleotide anabolism
nucleobase, nucleoside and nucleotide biosynthesis
nucleobase, nucleoside and nucleotide formation
nucleobase, nucleoside and nucleotide synthesis
biological_process
GO:0034404
nucleobase-containing small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GOC:mah
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0016249
cellular protein localisation
channel localizer activity
biological_process
GO:0034613
cellular protein localization
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:mah
cellular protein localisation
GOC:mah
channel localizer activity
GOC:mah
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular nitrogen compound metabolism
biological_process
GO:0034641
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
cellular response to UV light stimulus
cellular response to UV radiation stimulus
cellular response to ultraviolet light stimulus
cellular response to ultraviolet radiation stimulus
biological_process
GO:0034644
cellular response to UV
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GOC:mah
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GO:0034961
cellular biopolymer biosynthetic process
cellular macromolecule anabolism
cellular macromolecule biosynthesis
cellular macromolecule formation
cellular macromolecule synthesis
biological_process
GO:0034645
cellular macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GOC:mah
cellular biopolymer biosynthetic process
GOC:mtg_chebi_dec09
cellular macromolecule anabolism
GOC:mah
cellular macromolecule biosynthesis
GOC:mah
cellular macromolecule formation
GOC:mah
cellular macromolecule synthesis
GOC:mah
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
nucleobase, nucleoside, nucleotide and nucleic acid anabolism
nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis
nucleobase, nucleoside, nucleotide and nucleic acid formation
nucleobase, nucleoside, nucleotide and nucleic acid synthesis
biological_process
GO:0034654
nucleobase-containing compound biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
regulation of membrane transport
biological_process
GO:0034762
regulation of transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
down regulation of transmembrane transport
down-regulation of transmembrane transport
downregulation of transmembrane transport
negative regulation of membrane transport
inhibition of transmembrane transport
biological_process
GO:0034763
negative regulation of transmembrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
positive regulation of membrane transport
up regulation of transmembrane transport
up-regulation of transmembrane transport
upregulation of transmembrane transport
activation of transmembrane transport
stimulation of transmembrane transport
biological_process
GO:0034764
positive regulation of transmembrane transport
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
regulation of ion membrane transport
regulation of transmembrane ion transport
biological_process
GO:0034765
regulation of ion transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
regulation of transmembrane ion transport
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
down regulation of transmembrane ion transport
down-regulation of transmembrane ion transport
downregulation of transmembrane ion transport
negative regulation of ion membrane transport
negative regulation of transmembrane ion transport
inhibition of transmembrane ion transport
biological_process
GO:0034766
negative regulation of ion transmembrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
negative regulation of transmembrane ion transport
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
positive regulation of ion membrane transport
positive regulation of transmembrane ion transport
up regulation of transmembrane ion transport
up-regulation of transmembrane ion transport
upregulation of transmembrane ion transport
activation of transmembrane ion transport
stimulation of transmembrane ion transport
biological_process
GO:0034767
positive regulation of ion transmembrane transport
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GO:0035083
GO:0035084
ciliary axoneme assembly
cilium axoneme assembly
flagellar axoneme assembly
flagellum axoneme assembly
biological_process
axoneme biogenesis
cilium axoneme biogenesis
GO:0035082
Note that cilia and eukaryotic flagella are deemed to be equivalent.
axoneme assembly
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GOC:bf
GOC:cilia
GOC:jl
ISBN:0815316194
axoneme biogenesis
GOC:mah
cilium axoneme biogenesis
GOC:mah
Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
Wikipedia:Operant_conditioning
instrumental conditioning
biological_process
GO:0035106
operant conditioning
Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
PMID:14662373
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
Wikipedia:Social_behavior
social behaviour
biological_process
cooperative behavior
GO:0035176
Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.
social behavior
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
GOC:jh2
PMID:12848939
Wikipedia:Social_behavior
Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.
RNA-mediated posttranscriptional gene silencing
biological_process
sense-PTGS
GO:0035194
posttranscriptional gene silencing by RNA
Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.
GOC:aruk
GOC:bc
GOC:mah
GOC:rl
PMID:15020054
PMID:15066275
PMID:15066283
PMID:23985560
PMID:28379604
RNA-mediated posttranscriptional gene silencing
GOC:dph
GOC:tb
The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
biological_process
GO:0035239
tube morphogenesis
The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
GOC:bf
PMID:14624839
Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
molecular_function
GO:0035257
nuclear hormone receptor binding
Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
GOC:bf
Interacting selectively and non-covalently with a steroid hormone receptor.
molecular_function
GO:0035258
steroid hormone receptor binding
Interacting selectively and non-covalently with a steroid hormone receptor.
GOC:bf
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
biological_process
body growth
GO:0035264
multicellular organism growth
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
GOC:bf
GOC:curators
GOC:dph
GOC:tb
The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.
biological_process
GO:0035295
tube development
The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.
PMID:12526790
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
rfoulger
2010-04-16T11:06:12Z
response to fiblaferon
response to fibroblast interferon
response to interferon beta
biological_process
response to beta-1 interferon
GO:0035456
response to interferon-beta
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
GOC:sl
PMID:9561374
PR:000008924
response to fiblaferon
GOC:sl
response to fibroblast interferon
GOC:sl
response to interferon beta
GOC:hp
PR:000008924
response to beta-1 interferon
GOC:sl
The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
rfoulger
2010-04-19T10:21:41Z
vitamin membrane transport
biological_process
GO:0035461
Note that this term is not intended for use in annotating lateral movement within membranes.
vitamin transmembrane transport
The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GOC:bf
Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
rfoulger
2010-04-22T10:49:09Z
biological_process
GO:0035470
positive regulation of vascular wound healing
Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GOC:rph
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
rfoulger
2010-05-14T01:14:37Z
GO:0007242
GO:0007243
GO:0023013
GO:0023034
intracellular signaling chain
intracellular protein kinase cascade
intracellular signal transduction pathway
protein kinase cascade
signal transmission via intracellular cascade
biological_process
intracellular signaling cascade
intracellular signaling pathway
signal transduction via intracellular signaling cascade
GO:0035556
intracellular signal transduction
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GOC:bf
GOC:jl
GOC:signaling
ISBN:3527303782
intracellular signaling chain
ISBN:3527303782
intracellular protein kinase cascade
GOC:signaling
protein kinase cascade
GOC:signaling
intracellular signaling cascade
GOC:signaling
The directed movement of a protein to a specific location within the extracellular region.
rfoulger
2010-11-09T10:25:08Z
establishment of protein localisation in extracellular region
establishment of protein localization in extracellular region
biological_process
GO:0035592
establishment of protein localization to extracellular region
The directed movement of a protein to a specific location within the extracellular region.
GOC:BHF
GOC:bf
establishment of protein localisation in extracellular region
GOC:mah
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
rfoulger
2011-03-17T10:55:42Z
intraflagellar transport
Reactome:R-HSA-5620924.2
biological_process
intraciliary transport involved in cilium morphogenesis
intraflagellar transport involved in cilium morphogenesis
GO:0035735
intraciliary transport involved in cilium assembly
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
GOC:bf
GOC:cilia
Reactome:R-HSA-5620924.2
The process in which an organism effects a change in the structure or processes of another organism.
https://github.com/geneontology/go-ontology/issues/18605
rfoulger
2011-04-21T01:31:51Z
modification of morphology or physiology of other organism
regulation of morphology of other organism
regulation of physiological process of other organism
regulation of physiology of other organism
biological_process
regulation of morphology or physiology of other organism
GO:0035821
modulation of process of other organism
The process in which an organism effects a change in the structure or processes of another organism.
GOC:bf
regulation of morphology of other organism
GOC:bf
regulation of physiological process of other organism
GOC:bf
regulation of physiology of other organism
GOC:bf
regulation of morphology or physiology of other organism
GOC:bf
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.
rfoulger
2011-07-22T02:59:40Z
down regulation of peptidase activity in other organism
downregulation of peptidase activity in other organism
down-regulation of protease activity in other organism
inhibition of protease activity in other organism
negative regulation of protease activity in other organism
biological_process
GO:0035940
negative regulation of peptidase activity in other organism
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.
GOC:klp
PMID:10595640
down regulation of peptidase activity in other organism
GOC:bf
downregulation of peptidase activity in other organism
GOC:bf
down-regulation of protease activity in other organism
GOC:bf
inhibition of protease activity in other organism
GOC:bf
negative regulation of protease activity in other organism
GOC:bf
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
rfoulger
2012-04-26T01:47:12Z
protein modification
biological_process
GO:0036211
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GOC:bf
GOC:jl
protein modification
GOC:bf
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
rfoulger
2012-07-09T01:26:24Z
biological_process
GO:0036270
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to diuretic
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
rfoulger
2012-07-09T01:30:57Z
response to MPD
response to MPH
response to ritalin
biological_process
GO:0036271
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to methylphenidate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
GOC:hp
Wikipedia:Methylphenidate
response to MPD
CHEBI:6887
response to MPH
CHEBI:6887
response to ritalin
CHEBI:6887
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
rfoulger
2012-07-09T01:36:03Z
response to 2',2'-difluorodeoxycytidine
response to 2'-deoxy-2',2'-difluorocytidine
biological_process
GO:0036272
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to gemcitabine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
GOC:hp
Wikipedia:Gemcitabine
response to 2',2'-difluorodeoxycytidine
CHEBI:175901
response to 2'-deoxy-2',2'-difluorocytidine
CHEBI:175901
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
rfoulger
2012-07-09T01:54:01Z
biological_process
response to HMG-CoA reductase inhibitor
response to hydroxymethylglutaryl-CoA reductase inhibitor
GO:0036273
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to statin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
GOC:hp
response to HMG-CoA reductase inhibitor
CHEBI:35664
response to hydroxymethylglutaryl-CoA reductase inhibitor
CHEBI:35664
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
rfoulger
2012-07-09T02:02:26Z
biological_process
GO:0036274
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to lapatinib
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
rfoulger
2012-07-09T02:08:23Z
response to 5-fluoropyrimidine-2,4(1H,3H)-dione
response to fluorouracil
biological_process
GO:0036275
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to 5-fluorouracil
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
GOC:hp
response to 5-fluoropyrimidine-2,4(1H,3H)-dione
CHEBI:46345
response to fluorouracil
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
rfoulger
2012-07-09T02:12:44Z
biological_process
GO:0036276
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to antidepressant
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
rfoulger
2012-07-09T02:40:12Z
biological_process
GO:0036277
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to anticonvulsant
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
rfoulger
2012-07-16T05:01:29Z
biological_process
GO:0036287
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to iloperidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
rfoulger
2012-07-16T05:03:56Z
biological_process
GO:0036288
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to ximelagatran
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
GOC:hp
Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.
rfoulger
2013-05-30T10:36:05Z
biological_process
GO:0036385
nucleoid DNA packaging
Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.
GOC:bf
GOC:bhm
Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling.
rfoulger
2013-05-30T10:41:08Z
chromosomal compaction
nucleoid compaction
prokaryotic DNA condensation
biological_process
GO:0036386
bacterial nucleoid DNA packaging
Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling.
GOC:bf
GOC:bhm
PMID:17097674
PMID:17360520
chromosomal compaction
PMID:17097674
nucleoid compaction
PMID:17097674
prokaryotic DNA condensation
Wikipedia:DNA_condensation
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
rfoulger
2011-08-01T02:45:27Z
GO:0004872
GO:0019041
receptor activity
receptor activity involved in signal transduction
molecular_function
GO:0038023
signaling receptor activity
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GOC:bf
GOC:signaling
receptor activity involved in signal transduction
GOC:bf
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO:0048590
biological_process
growth pattern
non-developmental growth
GO:0040007
See also the biological process term 'cell growth ; GO:0016049'.
growth
The increase in size or mass of an entire organism, a part of an organism or a cell.
GOC:bf
GOC:ma
non-developmental growth
GOC:mah
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
biological_process
GO:0040008
regulation of growth
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
GOC:ems
GOC:mah
Self-propelled movement of a cell or organism from one location to another.
biological_process
GO:0040011
locomotion
Self-propelled movement of a cell or organism from one location to another.
GOC:dgh
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
biological_process
GO:0040012
regulation of locomotion
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
GOC:ems
Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
down regulation of locomotion
down-regulation of locomotion
downregulation of locomotion
inhibition of locomotion
biological_process
GO:0040013
negative regulation of locomotion
Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
GOC:go_curators
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
regulation of body growth
regulation of body size
biological_process
GO:0040014
regulation of multicellular organism growth
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
GOC:dph
GOC:ems
GOC:tb
regulation of body growth
GOC:dph
GOC:tb
regulation of body size
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
negative regulation of body growth
negative regulation of body size
biological_process
GO:0040015
negative regulation of multicellular organism growth
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
GOC:dph
GOC:ems
GOC:tb
negative regulation of body growth
GOC:dph
GOC:tb
negative regulation of body size
GOC:dph
GOC:tb
The first few specialized divisions of an activated animal egg.
biological_process
GO:0040016
embryonic cleavage
The first few specialized divisions of an activated animal egg.
GOC:clt
ISBN:0070524300
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
up regulation of locomotion
up-regulation of locomotion
upregulation of locomotion
activation of locomotion
stimulation of locomotion
biological_process
GO:0040017
positive regulation of locomotion
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
positive regulation of body growth
positive regulation of body size
biological_process
GO:0040018
positive regulation of multicellular organism growth
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
GOC:dph
GOC:go_curators
GOC:tb
positive regulation of body growth
GOC:dph
GOC:tb
positive regulation of body size
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of embryonic development.
up regulation of embryonic development
up-regulation of embryonic development
upregulation of embryonic development
activation of embryonic development
stimulation of embryonic development
biological_process
GO:0040019
positive regulation of embryonic development
Any process that activates or increases the frequency, rate or extent of embryonic development.
GOC:go_curators
Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
regulation of meiosis
biological_process
GO:0040020
regulation of meiotic nuclear division
Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
GOC:ems
GOC:ma
regulation of meiosis
GOC:vw
Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
biological_process
GO:0040029
regulation of gene expression, epigenetic
Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
PMID:10521337
PMID:11498582
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033649
cellular_component
GO:0042025
host cell nucleus
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
The behavior of an organism in response to an odor.
behavioral response to scent
behavioral response to smell
behavioural response to odour
behavioural response to scent
behavioural response to smell
olfactory behaviour
biological_process
GO:0042048
olfactory behavior
The behavior of an organism in response to an odor.
GOC:jid
GOC:pr
The series of events that restore integrity to a damaged tissue, following an injury.
Wikipedia:Wound_healing
biological_process
GO:0042060
wound healing
The series of events that restore integrity to a damaged tissue, following an injury.
GOC:bf
PMID:15269788
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
GO:0035734
Wikipedia:Intraflagellar_transport
intraflagellar transport
intraflagellar transport involved in cilium organization
intraflagellar transport involved in microtubule-based flagellum organisation
biological_process
IFT
GO:0042073
Note that we deem cilium and microtubule-based flagellum to be equivalent.
intraciliary transport
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
GOC:cilia
GOC:kmv
PMID:17981739
PMID:18180368
PMID:22869374
Reactome:R-HSA-5620924.2
The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
GO:0048131
germ-line stem cell renewal
biological_process
GO:0042078
germ-line stem cell division
The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
GOC:jid
PMID:2279698
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
macrophage polarization
biological_process
GO:0042116
macrophage activation
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GOC:mgi_curators
ISBN:0781735149
PMID:14506301
Any process that modulates the frequency, rate or extent of cell proliferation.
biological_process
regulation of cell proliferation
GO:0042127
regulation of cell population proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
GOC:jl
Either of the lipid bilayers that surround a plastid and form the plastid envelope.
cellular_component
GO:0042170
plastid membrane
Either of the lipid bilayers that surround a plastid and form the plastid envelope.
GOC:mah
The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.
terpene metabolism
biological_process
GO:0042214
terpene metabolic process
The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.
GOC:curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
response to chemical stimulus
response to chemical substance
biological_process
GO:0042221
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to chemical
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GOC:jl
response to chemical stimulus
GOC:dos
The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
purine metabolic process
purine metabolism
purine nucleoside metabolism
biological_process
GO:0042278
purine nucleoside metabolic process
The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GOC:jl
ISBN:0140512713
Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.
regulation of REM sleep
biological_process
GO:0042320
regulation of circadian sleep/wake cycle, REM sleep
Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.
GOC:jl
PMID:11506998
Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
down regulation of circadian sleep/wake cycle, sleep
down-regulation of circadian sleep/wake cycle, sleep
downregulation of circadian sleep/wake cycle, sleep
negative regulation of sleep
inhibition of circadian sleep/wake cycle, sleep
biological_process
GO:0042321
negative regulation of circadian sleep/wake cycle, sleep
Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GOC:go_curators
GOC:jl
ISBN:0192800981
Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.
down regulation of circadian sleep/wake cycle, REM sleep
down-regulation of circadian sleep/wake cycle, REM sleep
downregulation of circadian sleep/wake cycle, REM sleep
negative regulation of REM sleep
inhibition of circadian sleep/wake cycle, REM sleep
biological_process
GO:0042322
negative regulation of circadian sleep/wake cycle, REM sleep
Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.
GOC:go_curators
GOC:jl
Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.
down regulation of circadian sleep/wake cycle, non-REM sleep
down-regulation of circadian sleep/wake cycle, non-REM sleep
downregulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of non-REM sleep
inhibition of circadian sleep/wake cycle, non-REM sleep
biological_process
GO:0042323
negative regulation of circadian sleep/wake cycle, non-REM sleep
Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.
GOC:jl
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
biological_process
GO:0042325
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
GOC:jl
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
down regulation of phosphorylation
down-regulation of phosphorylation
downregulation of phosphorylation
inhibition of phosphorylation
biological_process
GO:0042326
negative regulation of phosphorylation
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
GOC:jl
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
up regulation of phosphorylation
up-regulation of phosphorylation
upregulation of phosphorylation
activation of phosphorylation
stimulation of phosphorylation
biological_process
GO:0042327
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
GOC:jl
The directed movement of a motile cell or organism in response to an external stimulus.
Wikipedia:Taxis
directed movement in response to stimulus
biological_process
GO:0042330
taxis
The directed movement of a motile cell or organism in response to an external stimulus.
GOC:jl
ISBN:0192801023
The directed movement of a motile cell or organism in response to light.
GO:0046953
Wikipedia:Phototaxis
phototactic behavior
phototactic behaviour
taxis in response to light
biological_process
GO:0042331
phototaxis
The directed movement of a motile cell or organism in response to light.
GOC:jl
ISBN:0192800981
The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
tocopherol metabolic process
tocopherol metabolism
vitamin E metabolism
alpha-tocopherol metabolic process
alpha-tocopherol metabolism
biological_process
GO:0042360
vitamin E metabolic process
The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
purine nucleoside anabolism
purine nucleoside biosynthesis
purine nucleoside formation
purine nucleoside synthesis
biological_process
GO:0042451
purine nucleoside biosynthetic process
The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GOC:go_curators
The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
ribonucleoside anabolism
ribonucleoside biosynthesis
ribonucleoside formation
ribonucleoside synthesis
biological_process
GO:0042455
ribonucleoside biosynthetic process
The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GOC:jl
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
GO:0042477
Wikipedia:Odontogenesis
odontogeny
odontosis
tooth morphogenesis
odontogenesis of calcareous or chitinous tooth
biological_process
tooth development
GO:0042476
odontogenesis
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042484
regulation of tooth development
regulation of odontogenesis of calcareous or chitinous tooth
biological_process
GO:0042481
regulation of odontogenesis
Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.
GOC:jl
Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042485
positive regulation of tooth development
up regulation of odontogenesis
up-regulation of odontogenesis
upregulation of odontogenesis
activation of odontogenesis
positive regulation of odontogenesis of calcareous or chitinous tooth
stimulation of odontogenesis
biological_process
GO:0042482
positive regulation of odontogenesis
Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042486
down regulation of odontogenesis
down-regulation of odontogenesis
downregulation of odontogenesis
negative regulation of tooth development
inhibition of odontogenesis
negative regulation of odontogenesis of calcareous or chitinous tooth
biological_process
GO:0042483
negative regulation of odontogenesis
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
GO:0017035
biological_process
drug resistance
drug susceptibility/resistance
GO:0042493
response to drug
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
response to hyperosmotic salt stress
biological_process
salt tolerance
GO:0042538
hyperosmotic salinity response
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GOC:jl
A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
biological_process
GO:0042551
neuron maturation
A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
GOC:dph
GOC:jl
The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0019721
pteridine and derivative metabolic process
pteridine and derivative metabolism
pteridine-containing compound metabolism
pterin metabolic process
pterin metabolism
biological_process
GO:0042558
pteridine-containing compound metabolic process
The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GOC:jl
ISBN:0198506732
Any biological process involved in the maintenance of an internal steady state.
GO:0032844
GO:0032845
GO:0032846
homeostasis
activation of homeostatic process
inhibition of homeostatic process
biological_process
negative regulation of homeostatic process
positive regulation of homeostatic process
regulation of homeostatic process
GO:0042592
homeostatic process
Any biological process involved in the maintenance of an internal steady state.
GOC:jl
ISBN:0395825172
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
biological_process
GO:0042593
glucose homeostasis
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
biological_process
GO:0042594
response to starvation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
GOC:go_curators
Any process that results in a change in the behavior of an organism as a result of deprivation of water.
behavioral response to drought
behavioral response to thirst
behavioural response to water deprivation
biological_process
GO:0042630
behavioral response to water deprivation
Any process that results in a change in the behavior of an organism as a result of deprivation of water.
GOC:jl
The region of a chloroplast to which the DNA is confined.
cellular_component
GO:0042644
chloroplast nucleoid
The region of a chloroplast to which the DNA is confined.
GOC:jl
The region of a mitochondrion to which the DNA is confined.
cellular_component
GO:0042645
mitochondrial nucleoid
The region of a mitochondrion to which the DNA is confined.
GOC:jl
The region of a plastid to which the DNA is confined.
cellular_component
GO:0042646
plastid nucleoid
The region of a plastid to which the DNA is confined.
GOC:jl
The region of a proplastid to which the DNA is confined.
cellular_component
GO:0042647
proplastid nucleoid
The region of a proplastid to which the DNA is confined.
GOC:jl
A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
https://github.com/geneontology/go-ontology/issues/17727
biological_process
GO:0042710
biofilm formation
A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GOC:di
PMID:11932229
The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
thiamin and derivative metabolic process
thiamin and derivative metabolism
thiamin-containing compound metabolic process
thiamine and derivative metabolic process
thiamine and derivative metabolism
thiamine-containing compound metabolism
vitamin B1 and derivative metabolic process
vitamin B1 and derivative metabolism
biological_process
GO:0042723
thiamine-containing compound metabolic process
The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
GOC:jl
The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
biological_process
GO:0042745
circadian sleep/wake cycle
The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
GOC:jl
http://www.sleepquest.com
A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
biological_process
GO:0042747
circadian sleep/wake cycle, REM sleep
A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
GOC:jl
ISBN:0395825172
All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.
biological_process
GO:0042748
circadian sleep/wake cycle, non-REM sleep
All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.
GOC:jl
http://www.sleepquest.com
Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.
biological_process
GO:0042749
regulation of circadian sleep/wake cycle
Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.
GOC:jl
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
biological_process
GO:0042752
regulation of circadian rhythm
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
GOC:dph
GOC:jl
GOC:tb
Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
up regulation of circadian rhythm
up-regulation of circadian rhythm
upregulation of circadian rhythm
activation of circadian rhythm
stimulation of circadian rhythm
biological_process
GO:0042753
positive regulation of circadian rhythm
Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
down regulation of circadian rhythm
down-regulation of circadian rhythm
downregulation of circadian rhythm
inhibition of circadian rhythm
biological_process
GO:0042754
negative regulation of circadian rhythm
Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
GOC:go_curators
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
eating behaviour
biological_process
GO:0042755
eating behavior
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
GOC:jl
GOC:pr
PMID:19361967
The specific behavior of an organism relating to the intake of liquids, especially water.
drinking behaviour
biological_process
GO:0042756
drinking behavior
The specific behavior of an organism relating to the intake of liquids, especially water.
GOC:curators
GOC:pr
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
regulation of sulfur metabolism
regulation of sulphur metabolic process
regulation of sulphur metabolism
biological_process
GO:0042762
regulation of sulfur metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
GOC:go_curators
The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0042886
amide transport
The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
ISBN:0198506732
Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.
amine/amide/polyamine channel activity
molecular_function
GO:0042887
amide transmembrane transporter activity
Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.
GOC:jl
ISBN:0198506732
The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0042908
xenobiotic transport
The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:go_curators
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0015238
GO:0015239
GO:0015559
GO:0015564
GO:0090484
molecular_function
drug transmembrane transporter activity
drug transporter activity
multidrug efflux pump activity
multidrug transporter activity
multidrug, alkane resistant pump activity
xenobiotic transporter activity
GO:0042910
xenobiotic transmembrane transporter activity
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GOC:go_curators
Any process that modulates the occurrence or rate of cell death by apoptotic process.
regulation of apoptosis
biological_process
apoptosis regulator activity
GO:0042981
This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
regulation of apoptotic process
Any process that modulates the occurrence or rate of cell death by apoptotic process.
GOC:jl
GOC:mtg_apoptosis
A prolongation or process extending from a cell, e.g. a flagellum or axon.
cell process
cellular process
cellular projection
cellular_component
GO:0042995
cell projection
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
http://www.cogsci.princeton.edu/~wn/
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
NIF_Subcellular:sao867568886
neuron process
neuron protrusion
neuronal cell projection
neurite
cellular_component
nerve fiber
GO:0043005
neuron projection
neuron projection
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GOC:jl
http://www.cogsci.princeton.edu/~wn/
neuron protrusion
NIF_Subcellular:sao250931889
nerve fiber
GOC:dph
Any process that modulates the frequency or rate of macrophage activation.
regulation of macrophage polarization
biological_process
GO:0043030
regulation of macrophage activation
Any process that modulates the frequency or rate of macrophage activation.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
down regulation of macrophage activation
down-regulation of macrophage activation
downregulation of macrophage activation
negative regulation of macrophage polarization
inhibition of macrophage activation
biological_process
GO:0043031
negative regulation of macrophage activation
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
GOC:jl
Any process that stimulates, induces or increases the rate of macrophage activation.
positive regulation of macrophage polarization
up regulation of macrophage activation
up-regulation of macrophage activation
upregulation of macrophage activation
activation of macrophage activation
stimulation of macrophage activation
biological_process
GO:0043032
positive regulation of macrophage activation
Any process that stimulates, induces or increases the rate of macrophage activation.
GOC:jl
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.
biological_process
de novo DNA methylation
GO:0043045
DNA methylation involved in embryo development
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.
GOC:go_curators
PMID:12138111
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
biological_process
de novo DNA methylation
GO:0043046
DNA methylation involved in gamete generation
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
GOC:go_curators
PMID:12138111
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
extracellular structure organisation
extracellular structure organization and biogenesis
biological_process
GO:0043062
extracellular structure organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
extracellular structure organization and biogenesis
GOC:dph
GOC:jl
GOC:mah
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
up regulation of apoptosis
up-regulation of apoptosis
upregulation of apoptosis
activation of apoptosis
positive regulation of apoptosis
stimulation of apoptosis
biological_process
pro-apoptosis
GO:0043065
This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
positive regulation of apoptotic process
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
GOC:jl
GOC:mtg_apoptosis
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
GO:0006916
anti-apoptosis
down regulation of apoptosis
down-regulation of apoptosis
downregulation of apoptosis
inhibition of apoptosis
negative regulation of apoptosis
biological_process
apoptosis inhibitor activity
pro-survival
GO:0043066
This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
negative regulation of apoptotic process
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
GOC:jl
GOC:mtg_apoptosis
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043070
regulation of non-apoptotic programmed cell death
biological_process
GO:0043067
regulation of programmed cell death
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043071
up regulation of programmed cell death
up-regulation of programmed cell death
upregulation of programmed cell death
activation of programmed cell death
positive regulation of non-apoptotic programmed cell death
stimulation of programmed cell death
biological_process
GO:0043068
positive regulation of programmed cell death
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043072
down regulation of programmed cell death
down-regulation of programmed cell death
downregulation of programmed cell death
inhibition of programmed cell death
negative regulation of non-apoptotic programmed cell death
biological_process
GO:0043069
negative regulation of programmed cell death
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that activates or increases the activity of an enzyme.
GO:0048554
MIPS_funcat:18.02.01.01
positive regulation of enzyme activity
up regulation of enzyme activity
up-regulation of enzyme activity
upregulation of enzyme activity
activation of enzyme activity
activation of metalloenzyme activity
positive regulation of metalloenzyme activity
stimulation of enzyme activity
stimulation of metalloenzyme activity
up regulation of metalloenzyme activity
up-regulation of metalloenzyme activity
upregulation of metalloenzyme activity
biological_process
GO:0043085
positive regulation of catalytic activity
Any process that activates or increases the activity of an enzyme.
GOC:ebc
GOC:jl
GOC:tb
GOC:vw
positive regulation of enzyme activity
GOC:tb
Any process that stops or reduces the activity of an enzyme.
GO:0048553
down regulation of enzyme activity
down-regulation of enzyme activity
down-regulation of metalloenzyme activity
downregulation of enzyme activity
negative regulation of enzyme activity
down regulation of metalloenzyme activity
downregulation of metalloenzyme activity
inhibition of enzyme activity
inhibition of metalloenzyme activity
negative regulation of metalloenzyme activity
biological_process
GO:0043086
negative regulation of catalytic activity
Any process that stops or reduces the activity of an enzyme.
GOC:ebc
GOC:jl
GOC:tb
GOC:vw
negative regulation of enzyme activity
GOC:tb
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043283
GO:0044259
biopolymer metabolic process
macromolecule metabolism
organismal macromolecule metabolism
multicellular organismal macromolecule metabolic process
biological_process
GO:0043170
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:mah
biopolymer metabolic process
GOC:mtg_chebi_dec09
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
biological_process
GO:0043207
response to external biotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
GOC:go_curators
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
FMA:62983
NIF_Subcellular:sao593830697
Wikipedia:Myelin
Schwann cell myelin sheath
astrocyte sheath
oligodendrocyte myelin sheath
cellular_component
GO:0043209
myelin sheath
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
GOC:cjm
GOC:jl
NIF_Subcellular:sao593830697
Wikipedia:Myelin
astrocyte sheath
NIF_Subcellular:nlx_subcell_20090204
oligodendrocyte myelin sheath
NIF_Subcellular:sao1279474730
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
NIF_Subcellular:sao1539965131
Wikipedia:Organelle
cellular_component
GO:0043226
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
NIF_Subcellular:sao414196390
membrane-enclosed organelle
cellular_component
GO:0043227
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
NIF_Subcellular:sao1456184038
non-membrane-enclosed organelle
cellular_component
GO:0043228
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GOC:go_curators
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cellular_component
GO:0043229
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
cellular_component
GO:0043230
extracellular organelle
Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
GOC:jl
PMID:9914479
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular membrane-enclosed organelle
cellular_component
GO:0043231
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular non-membrane-enclosed organelle
cellular_component
GO:0043232
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GOC:go_curators
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
cellular_component
GO:0043233
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of protein complex assembly.
biological_process
regulation of protein complex assembly
GO:0043254
regulation of protein-containing complex assembly
Any process that modulates the frequency, rate or extent of protein complex assembly.
GOC:jl
Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0043269
regulation of ion transport
Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of ion transport
up-regulation of ion transport
upregulation of ion transport
activation of ion transport
stimulation of ion transport
biological_process
GO:0043270
positive regulation of ion transport
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of ion transport
down-regulation of ion transport
downregulation of ion transport
inhibition of ion transport
biological_process
GO:0043271
negative regulation of ion transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
biological_process
GO:0043278
response to morphine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
GOC:ef
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
biological_process
GO:0043279
response to alkaloid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
GOC:jl
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
up regulation of DNA binding
up-regulation of DNA binding
upregulation of DNA binding
activation of DNA binding
stimulation of DNA binding
biological_process
GO:0043388
positive regulation of DNA binding
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
down regulation of DNA binding
down-regulation of DNA binding
downregulation of DNA binding
inhibition of DNA binding
biological_process
GO:0043392
negative regulation of DNA binding
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
Any process that modulates the frequency, rate or extent of protein binding.
biological_process
GO:0043393
regulation of protein binding
Any process that modulates the frequency, rate or extent of protein binding.
GOC:go_curators
A series of molecular signals mediated by a steroid hormone binding to a receptor.
steroid hormone mediated signalling
biological_process
GO:0043401
steroid hormone mediated signaling pathway
A series of molecular signals mediated by a steroid hormone binding to a receptor.
PMID:12606724
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
biological_process
GO:0043412
macromolecule modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GOC:go_curators
The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
biological_process
GO:0043413
macromolecule glycosylation
The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
GOC:jl
The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
biological_process
GO:0043414
macromolecule methylation
The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
GOC:go_curators
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
keto acid metabolic process
keto acid metabolism
ketoacid metabolic process
ketoacid metabolism
oxo acid metabolic process
oxo acid metabolism
oxoacid metabolism
biological_process
GO:0043436
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
Wikipedia:Oxyacid
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
biological_process
GO:0043549
regulation of kinase activity
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:bf
The region of a bacterial cell to which the DNA is confined.
cellular_component
GO:0043590
bacterial nucleoid
The region of a bacterial cell to which the DNA is confined.
GOC:jl
The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
amide metabolism
biological_process
GO:0043603
cellular amide metabolic process
The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
GOC:curators
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
GO:0043618
regulation of transcription from RNA polymerase II promoter in response to stress
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:jl
Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
regulation of DNA-dependent transcription in response to stress
biological_process
GO:0043620
regulation of DNA-templated transcription in response to stress
Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:jl
GOC:txnOH
regulation of DNA-dependent transcription in response to stress
GOC:txnOH
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
dicarboxylate metabolic process
dicarboxylate metabolism
dicarboxylic acid metabolism
biological_process
GO:0043648
dicarboxylic acid metabolic process
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
ISBN:0198506732
The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
extracellular space of host
host extracellular space
cellular_component
GO:0043655
host extracellular space
The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
GOC:cc
That space within the plasma membrane of a host cell.
host intracellular
intracellular region of host
cellular_component
GO:0043656
host intracellular region
That space within the plasma membrane of a host cell.
GOC:cc
A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.
cellular_component
GO:0043657
host cell
A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.
GOC:jl
Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
GO:0043900
regulation of multi-organism process
Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
GO:0043901
negative regulation of multi-organism process
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
GO:0043902
positive regulation of multi-organism process
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
biological_process
GO:0043903
regulation of symbiosis, encompassing mutualism through parasitism
Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
GOC:jl
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
midori
2010-09-08T10:01:42Z
GO:0034600
GO:0034621
GO:0071822
protein complex subunit organisation
protein complex subunit organization
biological_process
cellular macromolecular complex organization
cellular macromolecular complex subunit organisation
cellular macromolecular complex subunit organization
macromolecular complex organization
macromolecular complex subunit organisation
macromolecular complex subunit organization
GO:0043933
protein-containing complex subunit organization
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
GOC:mah
protein complex subunit organisation
GOC:mah
Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
activation of enzyme activity in other organism
activation of enzyme activity in other organism during symbiotic interaction
biological_process
positive regulation of catalytic activity in other organism during symbiotic interaction
up regulation of enzyme activity in other organism during symbiotic interaction
up-regulation of enzyme activity in other organism during symbiotic interaction
upregulation of enzyme activity in other organism during symbiotic interaction
GO:0043946
positive regulation of catalytic activity in other organism involved in symbiotic interaction
Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
GOC:tb
positive regulation of catalytic activity in other organism during symbiotic interaction
GOC:dph
Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
positive regulation by symbiont of host catalytic activity
positive regulation by symbiont of host enzyme activity
up regulation by symbiont of host enzyme activity
up-regulation by symbiont of host enzyme activity
upregulation by symbiont of host enzyme activity
activation by symbiont of host enzyme activity
activation of host enzyme activity
biological_process
GO:0043948
induction by symbiont of host catalytic activity
Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
The process in which a symbiont organism effects a change in the structure or processes of its host organism.
https://github.com/geneontology/go-ontology/issues/18719
GO:0044004
GO:0044055
modulation by symbiont of host system process
regulation by symbiont of host system process
biological_process
disruption by symbiont of host cell
modification by symbiont of host biological process
modification by symbiont of host morphology or physiology
GO:0044003
modulation by symbiont of host process
The process in which a symbiont organism effects a change in the structure or processes of its host organism.
GOC:cc
true
A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
https://github.com/geneontology/go-ontology/issues/18814
GO:0052000
auto-aggregation
bfp-dependent aggregation
bundle-forming fimbriae-dependent aggregation
bundle-forming pili-dependent aggregation
tfp-dependent aggregation
type IV pili-dependent aggregation
biological_process
GO:0044010
single-species biofilm formation
A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GOC:cc
GOC:di
GOC:tb
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
biological_process
GO:0044011
single-species biofilm formation on inanimate substrate
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
GOC:cc
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
biological_process
GO:0044030
regulation of DNA methylation
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
GOC:jl
OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.
interaction with host via substance released outside of symbiont cells
biological_process
GO:0044046
This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.
obsolete interaction with host via substance released outside of symbiont
true
OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.
MITRE:tk
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
biological_process
GO:0044057
regulation of system process
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
GOC:jl
Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.
biological_process
GO:0044062
regulation of excretion
Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.
GOC:jl
The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
modulation by symbiont of host neurological system process
regulation by symbiont of host neurological system process
biological_process
GO:0044063
modulation by symbiont of host nervous system process
The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
MITRE:tk
Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.
modulation of host cellular process by symbiont
regulation by symbiont of host cellular process
regulation of host cellular process by symbiont
biological_process
GO:0044068
modulation by symbiont of host cellular process
Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.
MITRE:tk
The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.
modification of host anion transport by symbiont
biological_process
GO:0044069
modulation by symbiont of host anion transport
The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.
MITRE:tk
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0044070
regulation of anion transport
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery.
modification by symbiont of host cell cycle
modulation of host cell cycle by symbiont
regulation by symbiont of host cell cycle
biological_process
GO:0044071
modulation by symbiont of host cell cycle
The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery.
MITRE:tk
The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery.
biological_process
GO:0044072
negative regulation by symbiont of host cell cycle
The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery.
MITRE:tk
A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GO:0071843
cellular component biogenesis at cellular level
biological_process
GO:0044085
cellular component biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
biological_process
GO:0044087
regulation of cellular component biogenesis
Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GOC:jl
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
regulation of vacuole organisation
biological_process
regulation of vacuole biogenesis
GO:0044088
regulation of vacuole organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GOC:jl
GOC:mah
regulation of vacuole organisation
GOC:mah
regulation of vacuole biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
biological_process
GO:0044089
positive regulation of cellular component biogenesis
Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GOC:jl
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
positive regulation of vacuole organisation
biological_process
positive regulation of vacuole biogenesis
GO:0044090
positive regulation of vacuole organization
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GOC:jl
GOC:mah
positive regulation of vacuole organisation
GOC:mah
positive regulation of vacuole biogenesis
GOC:mah
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
jane
2009-04-21T04:07:27Z
biological_process
GO:0044092
negative regulation of molecular function
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:jl
Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
jane
2009-04-21T04:11:06Z
biological_process
GO:0044093
positive regulation of molecular function
Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:jl
The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.
jane
2009-07-30T02:22:33Z
GO:0044153
biological_process
growth during symbiotic interaction
growth on or near surface of other organism during symbiotic interaction
growth on or near surface of other organism involved in symbiotic interaction
GO:0044110
This term partially replaces the obsolete term 'growth or development during symbiotic interaction ; GO:0052171'. See also 'development during symbiotic interaction ; GO:0044111'.
growth involved in symbiotic interaction
The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.
GO:jl
GOC:pamgo_curators
growth during symbiotic interaction
GOC:dph
growth on or near surface of other organism during symbiotic interaction
GOC:tb
The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
jane
2009-07-30T02:26:46Z
GO:0044152
development on or near surface of other organism involved in symbiotic interaction
biological_process
development during symbiotic interaction
development on or near surface of other organism during symbiotic interaction
GO:0044111
This term partially replaces the obsolete term 'growth or development during symbiotic interaction ; GO:0052171'. See also 'growth during symbiotic interaction ; GO:0044110'.
development involved in symbiotic interaction
The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
GO:jl
GOC:pamgo_curators
development during symbiotic interaction
gOC:dph
development on or near surface of other organism during symbiotic interaction
GOC:dph
OBSOLETE. A secondary organism with which the first organism is interacting.
jane
2009-11-12T01:04:58Z
cellular_component
GO:0044215
This term was obsoleted because it represents an organism, which is outside the scope of GO.
obsolete other organism
true
OBSOLETE. A secondary organism with which the first organism is interacting.
GOC:jl
A cell of a secondary organism with which the first organism is interacting.
jane
2009-11-12T01:17:06Z
cellular_component
GO:0044216
other organism cell
A cell of a secondary organism with which the first organism is interacting.
GOC:jl
Any constituent part of a secondary organism with which the first organism is interacting.
jane
2009-11-12T01:18:21Z
cellular_component
GO:0044217
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
other organism part
Any constituent part of a secondary organism with which the first organism is interacting.
GOC:jl
The chemical reactions and pathways by which individual cells transform chemical substances.
cellular metabolism
biological_process
intermediary metabolism
GO:0044237
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
GOC:go_curators
intermediary metabolism
GOC:mah
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
primary metabolism
biological_process
GO:0044238
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GOC:go_curators
http://www.metacyc.org
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular breakdown
cellular catabolism
cellular degradation
biological_process
GO:0044248
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:jl
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular anabolism
cellular biosynthesis
cellular formation
cellular synthesis
biological_process
GO:0044249
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:jl
The chemical reactions and pathways involving lipids, as carried out by individual cells.
cellular lipid metabolism
biological_process
GO:0044255
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
GOC:jl
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0034960
cellular biopolymer metabolic process
cellular macromolecule metabolism
biological_process
GO:0044260
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GOC:mah
cellular biopolymer metabolic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
cellular protein metabolism
biological_process
GO:0044267
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GOC:jl
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
nitrogen compound anabolism
nitrogen compound biosynthesis
nitrogen compound formation
nitrogen compound synthesis
biological_process
GO:0044271
cellular nitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
jane
2010-01-26T12:05:20Z
small molecule metabolism
biological_process
GO:0044281
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule metabolic process
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:pde
GOC:vw
The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
jane
2010-01-26T12:06:49Z
small molecule biosynthesis
biological_process
GO:0044283
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:pde
GOC:vw
The process in which an organism effects a change in the function of proteins in a second organism.
janelomax
2011-10-27T01:28:16Z
biological_process
GO:0044359
modulation of molecular function in other organism
The process in which an organism effects a change in the function of proteins in a second organism.
GOC:jl
Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.
janelomax
2011-10-27T02:12:49Z
biological_process
GO:0044362
negative regulation of molecular function in other organism
Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.
GOC:jl
A process in which an organism has a negative effect on the functioning of the second organism's cells.
janelomax
2011-10-27T02:27:48Z
biological_process
GO:0044364
disruption of cells of other organism
A process in which an organism has a negative effect on the functioning of the second organism's cells.
GOC:jl
true
A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
https://github.com/geneontology/go-ontology/issues/14807
GO:0043298
GO:0044404
GO:0072519
GO:0085031
commensalism
host-pathogen interaction
parasitism
biological_process
symbiosis
symbiosis, encompassing mutualism through parasitism
symbiotic interaction
symbiotic interaction between host and organism
symbiotic interaction between organisms
symbiotic interaction between species
GO:0044403
symbiosis, encompassing mutualism through parasitism
symbiotic process
A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
GOC:cc
https://study.com/academy/lesson/symbiont-definition-lesson-quiz.html
Any process in which an organism has an effect on an organism of a different species.
interaction with another species
interspecies interaction
interspecies interaction with other organisms
biological_process
GO:0044419
interspecies interaction between organisms
Any process in which an organism has an effect on an organism of a different species.
GOC:cc
OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).
GO:0031012
extracellular matrix part
cellular_component
GO:0044420
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete extracellular matrix component
true
OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).
GOC:jl
OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
GO:0005576
NIF_Subcellular:sao9117790637
cellular_component
extracellular structure
GO:0044421
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete extracellular region part
true
OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
GOC:jl
extracellular structure
NIF_Subcellular:sao9117790637
OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0043226
cellular_component
GO:0044422
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete organelle part
true
OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GOC:jl
OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005622
cellular_component
GO:0044424
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete intracellular part
true
OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GOC:jl
OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016020
cellular_component
GO:0044425
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete membrane part
true
OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GOC:jl
OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0005618
cellular_component
GO:0044426
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cell wall part
true
OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:jl
OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0005634
NIF_Subcellular:sao1499850686
nuclear subcomponent
nucleus component
cellular_component
GO:0044428
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete nuclear part
true
OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GOC:jl
nuclear subcomponent
NIF_Subcellular:sao1499850686
OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GO:0005739
NIF_Subcellular:sao666410040
mitochondrial subcomponent
mitochondrion component
cellular_component
GO:0044429
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete mitochondrial part
true
OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GOC:jl
mitochondrial subcomponent
NIF_Subcellular:sao666410040
OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
GO:0005856
NIF_Subcellular:sao1635329413
cytoskeletal element
cytoskeleton component
cellular_component
GO:0044430
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cytoskeletal part
true
OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
GOC:jl
cytoskeletal element
NIF_Subcellular:sao1635329413
OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
GO:0005794
NIF_Subcellular:sao624292949
Golgi component
Golgi subcomponent
cellular_component
GO:0044431
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete Golgi apparatus part
true
OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
GOC:jl
Golgi subcomponent
NIF_Subcellular:sao624292949
OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
GO:0005783
ER component
cellular_component
GO:0044432
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete endoplasmic reticulum part
true
OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
GOC:jl
OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
GO:0031410
cellular_component
GO:0044433
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cytoplasmic vesicle part
true
OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
GOC:jl
OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009507
cellular_component
GO:0044434
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete chloroplast part
true
OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GOC:jl
OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GO:0009536
cellular_component
GO:0044435
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete plastid part
true
OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GOC:jl
OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms.
GO:0009579
cellular_component
GO:0044436
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete thylakoid part
true
OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms.
GOC:jl
OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.
GO:0005773
vacuole component
cellular_component
GO:0044437
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete vacuolar part
true
OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.
GOC:jl
OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0005929
GO:0044442
cilial part
cilium part
microtubule-based flagellum part
flagellar part
flagellum component
flagellum part
cellular_component
GO:0044441
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent.
obsolete ciliary part
true
OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:cilia
GOC:jl
OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005737
cytoplasm component
cellular_component
GO:0044444
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cytoplasmic part
true
OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GOC:jl
OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components.
GO:0005829
cytosol component
cellular_component
GO:0044445
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cytosolic part
true
OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components.
GOC:jl
OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043229
cellular_component
GO:0044446
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete intracellular organelle part
true
OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GOC:jl
OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis.
GO:0005730
nucleolus component
cellular_component
GO:0044452
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete nucleolar part
true
OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis.
GOC:jl
OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0045202
NIF_Subcellular:sao1784069613
cellular_component
synaptic component
GO:0044456
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete synapse part
synapse part
true
OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GOC:jl
synaptic component
NIF_Subcellular:sao1784069613
OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0005886
cellular_component
GO:0044459
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete plasma membrane part
true
OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GOC:jl
OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria).
GO:0030312
cellular_component
GO:0044462
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete external encapsulating structure part
true
OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria).
GOC:jl
OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0042995
cellular_component
GO:0044463
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete cell projection part
true
OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms.
CL:0000000
NIF_Subcellular:sao628508602
cellular subcomponent
cellular_component
protoplast
GO:0044464
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cell part
obsolete cell part
true
OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms.
GOC:jl
cellular subcomponent
NIF_Subcellular:sao628508602
protoplast
GOC:mah
A process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism.
janelomax
2012-03-20T04:48:41Z
biological_process
GO:0044531
modulation of programmed cell death in other organism
A process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism.
GOC:jl
A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.
janelomax
2012-03-21T11:17:18Z
regulation of apoptotic process in other organism
biological_process
GO:0044532
modulation of apoptotic process in other organism
A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.
GOC:jl
The tooth development process in which the teeth enter the mouth and become visible.
janelomax
2012-08-15T14:58:17Z
Wikipedia:Tooth_eruption
biological_process
GO:0044691
tooth eruption
The tooth development process in which the teeth enter the mouth and become visible.
Wikipedia:Tooth_eruption
true
true
A biological process that directly contributes to the process of producing new individuals, involving another organism.
janelomax
2012-09-19T15:56:30Z
biological_process
GO:0044703
multi-organism reproductive process
A biological process that directly contributes to the process of producing new individuals, involving another organism.
GOC:jl
The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species.
janelomax
2012-09-19T16:02:12Z
biological_process
GO:0044705
multi-organism reproductive behavior
The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species.
GOC:jl
GOC:pr
A multicellular organism process which involves another multicellular organism of the same or different species.
janelomax
2012-09-19T16:06:16Z
biological_process
GO:0044706
multi-multicellular organism process
A multicellular organism process which involves another multicellular organism of the same or different species.
GOC:jl
true
true
The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.
janelomax
2012-10-24T14:49:41Z
biological_process
changes in DNA methylation
GO:0044728
DNA methylation or demethylation
The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.
GOC:jl
true
Any process that is carried out at the cellular level which involves another organism of the same or different species.
janelomax
2012-12-11T17:00:50Z
biological_process
GO:0044764
multi-organism cellular process
Any process that is carried out at the cellular level which involves another organism of the same or different species.
GOC:jl
true
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
janelomax
2012-12-13T16:25:50Z
biological_process
GO:0044766
multi-organism transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
GOC:jl
true
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
janelomax
2013-03-27T15:09:58Z
microtubule-based flagellum organization
biological_process
GO:0044782
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:cilia
GOC:jl
A distinct period or stage in a biological process or cycle.
janelomax
2014-07-16T13:12:40Z
biological_process
GO:0044848
Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase.
biological phase
A distinct period or stage in a biological process or cycle.
GOC:jl
A membrane raft that is part of the plasma membrane.
janelomax
2014-07-23T15:55:23Z
cellular_component
GO:0044853
plasma membrane raft
A membrane raft that is part of the plasma membrane.
GOC:jl
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
Wikipedia:Lipid_raft
lipid raft
cellular_component
GEM domain
glycolipid-enriched membrane domain
GO:0045121
membrane raft
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
PMID:16645198
PMID:20044567
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
biological_process
GO:0045132
meiotic chromosome segregation
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
GOC:ai
GOC:mah
The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.
meiosis II, chromosome segregation
biological_process
GO:0045144
meiotic sister chromatid segregation
The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.
GOC:ai
ISBN:0815316194
The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
biological_process
GO:0045161
neuronal ion channel clustering
The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
PMID:11456440
The directed movement of a protein to a specific location.
establishment of protein localisation
protein positioning
protein recruitment
biological_process
GO:0045184
establishment of protein localization
The directed movement of a protein to a specific location.
GOC:bf
establishment of protein localisation
GOC:mah
Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
regulation of sleep
biological_process
GO:0045187
regulation of circadian sleep/wake cycle, sleep
Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GOC:jl
ISBN:0192800981
Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.
regulation of non-REM sleep
biological_process
GO:0045188
regulation of circadian sleep/wake cycle, non-REM sleep
Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.
GOC:go_curators
The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
NIF_Subcellular:sao914572699
Wikipedia:Chemical_synapse
synaptic junction
mixed synapse
cellular_component
electrotonic synapse
GO:0045202
synapse
synapse
The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GOC:aruk
ISBN:0198506732
PMID:24619342
PMID:29383328
PMID:31998110
mixed synapse
NIF_Subcellular:sao1506103497
electrotonic synapse
NIF_Subcellular:sao1311109124
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
Wikipedia:Immunologic_activation
immune cell activation
leucocyte activation
biological_process
GO:0045321
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GOC:add
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
biological_process
GO:0045472
response to ether
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
GOC:go_curators
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
circadian locomotor activity rhythm
biological_process
GO:0045475
locomotor rhythm
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
GOC:go_curators
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
biological_process
GO:0045595
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
down regulation of cell differentiation
down-regulation of cell differentiation
downregulation of cell differentiation
inhibition of cell differentiation
biological_process
GO:0045596
negative regulation of cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of cell differentiation.
up regulation of cell differentiation
up-regulation of cell differentiation
upregulation of cell differentiation
activation of cell differentiation
stimulation of cell differentiation
biological_process
GO:0045597
positive regulation of cell differentiation
Any process that activates or increases the frequency, rate or extent of cell differentiation.
GOC:go_curators
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
biological_process
GO:0045637
regulation of myeloid cell differentiation
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
down regulation of myeloid cell differentiation
down-regulation of myeloid cell differentiation
downregulation of myeloid cell differentiation
inhibition of myeloid cell differentiation
biological_process
GO:0045638
negative regulation of myeloid cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
up regulation of myeloid cell differentiation
up-regulation of myeloid cell differentiation
upregulation of myeloid cell differentiation
activation of myeloid cell differentiation
stimulation of myeloid cell differentiation
biological_process
GO:0045639
positive regulation of myeloid cell differentiation
Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
GOC:go_curators
Any process that modulates the frequency, rate or extent of erythrocyte differentiation.
regulation of RBC differentiation
regulation of red blood cell differentiation
biological_process
GO:0045646
regulation of erythrocyte differentiation
Any process that modulates the frequency, rate or extent of erythrocyte differentiation.
GOC:go_curators
regulation of RBC differentiation
CL:0000232
regulation of red blood cell differentiation
CL:0000232
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
down regulation of erythrocyte differentiation
down-regulation of erythrocyte differentiation
downregulation of erythrocyte differentiation
negative regulation of RBC differentiation
negative regulation of red blood cell differentiation
inhibition of erythrocyte differentiation
biological_process
GO:0045647
negative regulation of erythrocyte differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
GOC:go_curators
negative regulation of RBC differentiation
CL:0000232
negative regulation of red blood cell differentiation
CL:0000232
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
positive regulation of RBC differentiation
positive regulation of red blood cell differentiation
up regulation of erythrocyte differentiation
up-regulation of erythrocyte differentiation
upregulation of erythrocyte differentiation
activation of erythrocyte differentiation
stimulation of erythrocyte differentiation
biological_process
GO:0045648
positive regulation of erythrocyte differentiation
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
GOC:go_curators
positive regulation of RBC differentiation
CL:0000232
positive regulation of red blood cell differentiation
CL:0000232
Any process that modulates the frequency, rate or extent of neuron differentiation.
biological_process
GO:0045664
regulation of neuron differentiation
Any process that modulates the frequency, rate or extent of neuron differentiation.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
down regulation of neuron differentiation
down-regulation of neuron differentiation
downregulation of neuron differentiation
inhibition of neuron differentiation
biological_process
GO:0045665
negative regulation of neuron differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
up regulation of neuron differentiation
up-regulation of neuron differentiation
upregulation of neuron differentiation
activation of neuron differentiation
stimulation of neuron differentiation
biological_process
GO:0045666
positive regulation of neuron differentiation
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
GOC:go_curators
Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.
biological_process
GO:0045700
regulation of spermatid nuclear differentiation
Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.
down regulation of spermatid nuclear differentiation
down-regulation of spermatid nuclear differentiation
downregulation of spermatid nuclear differentiation
inhibition of spermatid nuclear differentiation
biological_process
GO:0045701
negative regulation of spermatid nuclear differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.
up regulation of spermatid nuclear differentiation
up-regulation of spermatid nuclear differentiation
upregulation of spermatid nuclear differentiation
activation of spermatid nuclear differentiation
stimulation of spermatid nuclear differentiation
biological_process
GO:0045702
positive regulation of spermatid nuclear differentiation
Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
positive regulation of flagellum assembly
up regulation of cilium assembly
up-regulation of cilium assembly
upregulation of cilium assembly
activation of cilium assembly
stimulation of cilium assembly
biological_process
positive regulation of flagellum biogenesis
GO:0045724
positive regulation of cilium assembly
Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
GOC:cilia
GOC:go_curators
positive regulation of flagellum biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
down regulation of G-protein coupled receptor protein signaling pathway
down-regulation of G-protein coupled receptor protein signaling pathway
downregulation of G-protein coupled receptor protein signaling pathway
negative regulation of G protein coupled receptor protein signaling pathway
negative regulation of G protein coupled receptor protein signalling pathway
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of G-protein coupled receptor protein signalling pathway
negative regulation of G-protein-coupled receptor protein signalling pathway
negative regulation of GPCR protein signaling pathway
negative regulation of GPCR protein signalling pathway
inhibition of G-protein coupled receptor protein signaling pathway
biological_process
GO:0045744
negative regulation of G protein-coupled receptor signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
positive regulation of G protein coupled receptor protein signaling pathway
positive regulation of G protein coupled receptor protein signalling pathway
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of G-protein coupled receptor protein signalling pathway
positive regulation of G-protein-coupled receptor protein signaling pathway
positive regulation of G-protein-coupled receptor protein signalling pathway
positive regulation of GPCR protein signaling pathway
positive regulation of GPCR protein signalling pathway
up regulation of G-protein coupled receptor protein signaling pathway
up-regulation of G-protein coupled receptor protein signaling pathway
upregulation of G-protein coupled receptor protein signaling pathway
activation of G-protein coupled receptor protein signaling pathway
stimulation of G-protein coupled receptor protein signaling pathway
biological_process
GO:0045745
positive regulation of G protein-coupled receptor signaling pathway
Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
GOC:go_curators
Any process that modulates the frequency, rate or extent of angiogenesis.
biological_process
GO:0045765
regulation of angiogenesis
Any process that modulates the frequency, rate or extent of angiogenesis.
GOC:go_curators
Any process that activates or increases angiogenesis.
up regulation of angiogenesis
up-regulation of angiogenesis
upregulation of angiogenesis
activation of angiogenesis
stimulation of angiogenesis
biological_process
GO:0045766
positive regulation of angiogenesis
Any process that activates or increases angiogenesis.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.
down regulation of asymmetric cell division
down-regulation of asymmetric cell division
downregulation of asymmetric cell division
inhibition of asymmetric cell division
biological_process
GO:0045769
negative regulation of asymmetric cell division
Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of asymmetric cell division.
up regulation of asymmetric cell division
up-regulation of asymmetric cell division
upregulation of asymmetric cell division
activation of asymmetric cell division
stimulation of asymmetric cell division
biological_process
GO:0045770
positive regulation of asymmetric cell division
Any process that activates or increases the frequency, rate or extent of asymmetric cell division.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of cell adhesion.
up regulation of cell adhesion
up-regulation of cell adhesion
upregulation of cell adhesion
activation of cell adhesion
stimulation of cell adhesion
biological_process
GO:0045785
positive regulation of cell adhesion
Any process that activates or increases the frequency, rate or extent of cell adhesion.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
down regulation of progression through cell cycle
down-regulation of progression through cell cycle
downregulation of progression through cell cycle
negative regulation of cell cycle progression
negative regulation of progression through cell cycle
inhibition of progression through cell cycle
biological_process
GO:0045786
negative regulation of cell cycle
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
Any process that activates or increases the rate or extent of progression through the cell cycle.
positive regulation of cell cycle progression
positive regulation of progression through cell cycle
up regulation of progression through cell cycle
up-regulation of progression through cell cycle
upregulation of progression through cell cycle
activation of progression through cell cycle
stimulation of progression through cell cycle
biological_process
GO:0045787
positive regulation of cell cycle
Any process that activates or increases the rate or extent of progression through the cell cycle.
GOC:go_curators
positive regulation of progression through cell cycle
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
down regulation of isoprenoid metabolic process
down-regulation of isoprenoid metabolic process
downregulation of isoprenoid metabolic process
negative regulation of isoprenoid metabolism
inhibition of isoprenoid metabolic process
biological_process
GO:0045827
negative regulation of isoprenoid metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
positive regulation of isoprenoid metabolism
up regulation of isoprenoid metabolic process
up-regulation of isoprenoid metabolic process
upregulation of isoprenoid metabolic process
activation of isoprenoid metabolic process
stimulation of isoprenoid metabolic process
biological_process
GO:0045828
positive regulation of isoprenoid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
down regulation of lipid metabolic process
down-regulation of lipid metabolic process
downregulation of lipid metabolic process
negative regulation of lipid metabolism
inhibition of lipid metabolic process
biological_process
GO:0045833
negative regulation of lipid metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
positive regulation of lipid metabolism
up regulation of lipid metabolic process
up-regulation of lipid metabolic process
upregulation of lipid metabolic process
activation of lipid metabolic process
stimulation of lipid metabolic process
biological_process
GO:0045834
positive regulation of lipid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
down regulation of meiosis
down-regulation of meiosis
downregulation of meiosis
negative regulation of meiosis
inhibition of meiosis
biological_process
GO:0045835
negative regulation of meiotic nuclear division
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of meiosis.
positive regulation of meiosis
up regulation of meiosis
up-regulation of meiosis
upregulation of meiosis
activation of meiosis
stimulation of meiosis
biological_process
GO:0045836
positive regulation of meiotic nuclear division
Any process that activates or increases the frequency, rate or extent of meiosis.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
down regulation of mitosis
down-regulation of mitosis
downregulation of mitosis
negative regulation of mitosis
inhibition of mitosis
biological_process
GO:0045839
negative regulation of mitotic nuclear division
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
GOC:dph
GOC:go_curators
GOC:tb
Any process that activates or increases the frequency, rate or extent of mitosis.
positive regulation of mitosis
up regulation of mitosis
up-regulation of mitosis
upregulation of mitosis
activation of mitosis
mitogenic activity
stimulation of mitosis
biological_process
GO:0045840
positive regulation of mitotic nuclear division
Any process that activates or increases the frequency, rate or extent of mitosis.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
down regulation of proteolysis
down-regulation of proteolysis
downregulation of proteolysis
negative regulation of peptidolysis
inhibition of proteolysis
biological_process
GO:0045861
negative regulation of proteolysis
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
positive regulation of peptidolysis
up regulation of proteolysis
up-regulation of proteolysis
upregulation of proteolysis
activation of proteolysis
stimulation of proteolysis
biological_process
GO:0045862
positive regulation of proteolysis
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0016481
GO:0032582
GO:0061021
down regulation of transcription, DNA-dependent
down-regulation of transcription, DNA-dependent
downregulation of transcription, DNA-dependent
negative regulation of cellular transcription, DNA-dependent
negative regulation of transcription, DNA-dependent
inhibition of transcription, DNA-dependent
biological_process
down regulation of gene-specific transcription
down-regulation of gene-specific transcription
downregulation of gene-specific transcription
inhibition of gene-specific transcription
negative regulation of gene-specific transcription
transcription repressor activity
GO:0045892
negative regulation of transcription, DNA-templated
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
negative regulation of transcription, DNA-dependent
GOC:txnOH
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GO:0043193
GO:0045941
GO:0061020
positive regulation of cellular transcription, DNA-dependent
positive regulation of transcription, DNA-dependent
up regulation of transcription, DNA-dependent
up-regulation of transcription, DNA-dependent
upregulation of transcription, DNA-dependent
activation of transcription, DNA-dependent
stimulation of gene-specific transcription
stimulation of transcription, DNA-dependent
biological_process
activation of gene-specific transcription
positive regulation of gene-specific transcription
transcription activator activity
up regulation of gene-specific transcription
up-regulation of gene-specific transcription
upregulation of gene-specific transcription
GO:0045893
positive regulation of transcription, DNA-templated
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
positive regulation of transcription, DNA-dependent
GOC:txnOH
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
down regulation of carbohydrate metabolic process
down-regulation of carbohydrate metabolic process
downregulation of carbohydrate metabolic process
negative regulation of carbohydrate metabolism
inhibition of carbohydrate metabolic process
biological_process
GO:0045912
negative regulation of carbohydrate metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
positive regulation of carbohydrate metabolism
up regulation of carbohydrate metabolic process
up-regulation of carbohydrate metabolic process
upregulation of carbohydrate metabolic process
activation of carbohydrate metabolic process
stimulation of carbohydrate metabolic process
biological_process
GO:0045913
positive regulation of carbohydrate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
down regulation of growth
down-regulation of growth
downregulation of growth
inhibition of growth
biological_process
GO:0045926
negative regulation of growth
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
GOC:go_curators
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
up regulation of growth
up-regulation of growth
upregulation of growth
activation of growth
stimulation of growth
biological_process
GO:0045927
positive regulation of growth
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
down regulation of progression through mitotic cell cycle
down-regulation of progression through mitotic cell cycle
downregulation of progression through mitotic cell cycle
negative regulation of mitotic cell cycle progression
negative regulation of progression through mitotic cell cycle
inhibition of progression through mitotic cell cycle
biological_process
GO:0045930
negative regulation of mitotic cell cycle
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
negative regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
positive regulation of mitotic cell cycle progression
positive regulation of progression through mitotic cell cycle
up regulation of progression through mitotic cell cycle
up-regulation of progression through mitotic cell cycle
upregulation of progression through mitotic cell cycle
activation of progression through mitotic cell cycle
stimulation of progression through mitotic cell cycle
biological_process
GO:0045931
positive regulation of mitotic cell cycle
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
positive regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
biological_process
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0045934
negative regulation of nucleobase-containing compound metabolic process
Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
biological_process
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0045935
positive regulation of nucleobase-containing compound metabolic process
Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
down regulation of phosphate metabolic process
down-regulation of phosphate metabolic process
downregulation of phosphate metabolic process
negative regulation of phosphate metabolism
inhibition of phosphate metabolic process
biological_process
GO:0045936
negative regulation of phosphate metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
positive regulation of phosphate metabolism
up regulation of phosphate metabolic process
up-regulation of phosphate metabolic process
upregulation of phosphate metabolic process
activation of phosphate metabolic process
stimulation of phosphate metabolic process
biological_process
GO:0045937
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
positive regulation of sleep
up regulation of circadian sleep/wake cycle, sleep
up-regulation of circadian sleep/wake cycle, sleep
upregulation of circadian sleep/wake cycle, sleep
activation of circadian sleep/wake cycle, sleep
stimulation of circadian sleep/wake cycle, sleep
biological_process
GO:0045938
positive regulation of circadian sleep/wake cycle, sleep
Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0010552
GO:0045817
activation of transcription from RNA polymerase II promoter
positive regulation of transcription from Pol II promoter
positive regulation of transcription from RNA polymerase II promoter
stimulation of transcription from RNA polymerase II promoter
up regulation of transcription from RNA polymerase II promoter
up-regulation of transcription from RNA polymerase II promoter
upregulation of transcription from RNA polymerase II promoter
stimulation of global transcription from RNA polymerase II promoter
biological_process
activation of global transcription from RNA polymerase II promoter
positive regulation of gene-specific transcription from RNA polymerase II promoter
positive regulation of global transcription from Pol II promoter
positive regulation of transcription from RNA polymerase II promoter, global
up regulation of global transcription from RNA polymerase II promoter
up-regulation of global transcription from RNA polymerase II promoter
upregulation of global transcription from RNA polymerase II promoter
GO:0045944
positive regulation of transcription by RNA polymerase II
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GOC:go_curators
GOC:txnOH
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
down regulation of nucleoside metabolic process
down-regulation of nucleoside metabolic process
downregulation of nucleoside metabolic process
negative regulation of nucleoside metabolism
inhibition of nucleoside metabolic process
biological_process
GO:0045978
negative regulation of nucleoside metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
positive regulation of nucleoside metabolism
up regulation of nucleoside metabolic process
up-regulation of nucleoside metabolic process
upregulation of nucleoside metabolic process
activation of nucleoside metabolic process
stimulation of nucleoside metabolic process
biological_process
GO:0045979
positive regulation of nucleoside metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
down regulation of nucleotide metabolic process
down-regulation of nucleotide metabolic process
downregulation of nucleotide metabolic process
negative regulation of nucleotide metabolism
inhibition of nucleotide metabolic process
biological_process
GO:0045980
negative regulation of nucleotide metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
positive regulation of nucleotide metabolism
up regulation of nucleotide metabolic process
up-regulation of nucleotide metabolic process
upregulation of nucleotide metabolic process
activation of nucleotide metabolic process
stimulation of nucleotide metabolic process
biological_process
GO:0045981
positive regulation of nucleotide metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
down regulation of embryonic development
down-regulation of embryonic development
downregulation of embryonic development
inhibition of embryonic development
biological_process
GO:0045992
negative regulation of embryonic development
Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
GOC:go_curators
Any process that modulates the frequency, rate or extent of embryonic development.
biological_process
GO:0045995
regulation of embryonic development
Any process that modulates the frequency, rate or extent of embryonic development.
GOC:go_curators
Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.
positive regulation of REM sleep
up regulation of circadian sleep/wake cycle, REM sleep
up-regulation of circadian sleep/wake cycle, REM sleep
upregulation of circadian sleep/wake cycle, REM sleep
activation of circadian sleep/wake cycle, REM sleep
stimulation of circadian sleep/wake cycle, REM sleep
biological_process
GO:0046005
positive regulation of circadian sleep/wake cycle, REM sleep
Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.
GOC:go_curators
Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.
positive regulation of non-REM sleep
up regulation of circadian sleep/wake cycle, non-REM sleep
up-regulation of circadian sleep/wake cycle, non-REM sleep
upregulation of circadian sleep/wake cycle, non-REM sleep
activation of circadian sleep/wake cycle, non-REM sleep
stimulation of circadian sleep/wake cycle, non-REM sleep
biological_process
GO:0046010
positive regulation of circadian sleep/wake cycle, non-REM sleep
Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.
GOC:go_curators
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
ATP metabolism
biological_process
GO:0046034
ATP metabolic process
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
GOC:go_curators
The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
purine ribonucleoside metabolism
biological_process
GO:0046128
purine ribonucleoside metabolic process
The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
GOC:ai
The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
purine ribonucleoside anabolism
purine ribonucleoside biosynthesis
purine ribonucleoside formation
purine ribonucleoside synthesis
biological_process
GO:0046129
purine ribonucleoside biosynthetic process
The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
positive regulation of vitamin metabolism
up regulation of vitamin metabolic process
up-regulation of vitamin metabolic process
upregulation of vitamin metabolic process
activation of vitamin metabolic process
stimulation of vitamin metabolic process
biological_process
GO:0046136
positive regulation of vitamin metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
down regulation of vitamin metabolic process
down-regulation of vitamin metabolic process
downregulation of vitamin metabolic process
negative regulation of vitamin metabolism
inhibition of vitamin metabolic process
biological_process
GO:0046137
negative regulation of vitamin metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GOC:ai
The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.
ribose phosphate anabolism
ribose phosphate biosynthesis
ribose phosphate formation
ribose phosphate synthesis
biological_process
GO:0046390
ribose phosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.
GOC:ai
The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
heterocycle metabolism
biological_process
GO:0046483
heterocycle metabolic process
The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
ISBN:0198506732
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
biological_process
GO:0046649
lymphocyte activation
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GOC:mgi_curators
ISBN:0781735149
The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
folate metabolic process
folate metabolism
folic acid metabolism
vitamin B9 metabolic process
vitamin B9 metabolism
vitamin M metabolic process
vitamin M metabolism
biological_process
GO:0046655
folic acid metabolic process
The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
ISBN:0198506732
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
biological_process
antibiotic susceptibility/resistance
GO:0046677
response to antibiotic
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
GOC:ai
GOC:ef
A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.
Wikipedia:Chlorosome
cellular_component
GO:0046858
chlorosome
A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.
ISBN:0198506732
PMID:14729689
PMID:15298919
The controlled release of a substance by a cell or a tissue.
biological_process
GO:0046903
secretion
The controlled release of a substance by a cell or a tissue.
GOC:ai
The directed movement of substances within a cell.
jl
2013-12-18T14:04:50Z
GO:1902582
biological_process
single organism intracellular transport
single-organism intracellular transport
GO:0046907
intracellular transport
The directed movement of substances within a cell.
GOC:ai
single organism intracellular transport
GOC:TermGenie
The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
biological_process
GO:0046942
carboxylic acid transport
The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GOC:ai
Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
Reactome:R-HSA-390347
molecular_function
GO:0046943
carboxylic acid transmembrane transporter activity
Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GOC:ai
Reactome:R-HSA-390347
Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane
The directed movement of a cell or organism towards a source of light.
GO:0046954
positive phototactic behavior
positive phototactic behaviour
positive taxis in response to light
biological_process
GO:0046956
positive phototaxis
The directed movement of a cell or organism towards a source of light.
GOC:ai
The directed movement of a cell or organism away from a source of light.
GO:0046955
negative phototactic behavior
negative phototactic behaviour
negative taxis in response to light
biological_process
GO:0046957
negative phototaxis
The directed movement of a cell or organism away from a source of light.
GOC:ai
A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.
unconditional response
biological_process
GO:0046958
nonassociative learning
A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.
ISBN:0582227089
A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
Wikipedia:Habituation
biological_process
GO:0046959
habituation
A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
ISBN:0582227089
An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.
Wikipedia:Sensitization
biological_process
GO:0046960
sensitization
An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.
ISBN:0582227089
Any process that modulates the rate or extent of the response to osmotic stress.
biological_process
GO:0047484
regulation of response to osmotic stress
Any process that modulates the rate or extent of the response to osmotic stress.
GOC:ai
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
https://github.com/geneontology/go-ontology/issues/14220
midori
2010-09-13T04:51:59Z
GO:0071884
receptor agonist activity
signaling molecule
signaling receptor ligand activity
vitamin D receptor activator activity
molecular_function
GO:0048018
Definition discussed in https://github.com/geneontology/go-ontology/issues/14220
receptor ligand activity
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
GOC:kv
GOC:molecular_function_refactoring
GOC:pdt
receptor agonist activity
GOC:molecular_function_refactoring
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
Wikipedia:Apoplast
cellular_component
GO:0048046
apoplast
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
GOC:jid
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
autophagic death
programmed cell death by autophagy
programmed cell death by macroautophagy
biological_process
autosis
type II programmed cell death
GO:0048102
The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not.
autophagic cell death
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
GOC:autophagy
GOC:mah
GOC:mtg_apoptosis
PMID:18846107
PMID:23347517
programmed cell death by autophagy
GOC:pr
programmed cell death by macroautophagy
GOC:cjm
autosis
PMID:25236395
type II programmed cell death
GOC:sl
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
somatic stem cell renewal
biological_process
GO:0048103
somatic stem cell division
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
GOC:jid
ISBN:0582227089
The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
biological_process
GO:0048144
fibroblast proliferation
The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
GOC:jid
Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
biological_process
GO:0048145
regulation of fibroblast proliferation
Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GOC:jid
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
up regulation of fibroblast proliferation
up-regulation of fibroblast proliferation
upregulation of fibroblast proliferation
activation of fibroblast proliferation
stimulation of fibroblast proliferation
biological_process
GO:0048146
positive regulation of fibroblast proliferation
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
down regulation of fibroblast proliferation
down-regulation of fibroblast proliferation
downregulation of fibroblast proliferation
inhibition of fibroblast proliferation
biological_process
GO:0048147
negative regulation of fibroblast proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GOC:jid
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
biological_process
Golgi-derived vesicle transport
GO:0048193
Golgi vesicle transport
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
GOC:jid
ISBN:0716731363
PMID:10219233
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
Golgi vesicle targeting
dictyosome vesicle targeting
vesicle targeting, to, from or within dictyosome
biological_process
GO:0048199
vesicle targeting, to, from or within Golgi
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
GOC:jid
GOC:mah
ISBN:0716731363
PMID:10219233
Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
regulation of Golgi vesicle targeting
biological_process
GO:0048209
regulation of vesicle targeting, to, from or within Golgi
Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
GOC:jid
GOC:mah
ISBN:0716731363
PMID:10219233
Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
biological_process
GO:0048232
male gamete generation
Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
GOC:dph
GOC:jid
The volume enclosed by the membranes of the rough endoplasmic reticulum.
NIF_Subcellular:sao1819509473
RER lumen
rough ER lumen
cellular_component
GO:0048237
rough endoplasmic reticulum lumen
The volume enclosed by the membranes of the rough endoplasmic reticulum.
GOC:jid
The volume enclosed by the membranes of the smooth endoplasmic reticulum.
NIF_Subcellular:sao927884761
SER lumen
smooth ER lumen
cellular_component
GO:0048238
smooth endoplasmic reticulum lumen
The volume enclosed by the membranes of the smooth endoplasmic reticulum.
GOC:jid
The creation of two or more organelles by division of one organelle.
biological_process
GO:0048285
organelle fission
The creation of two or more organelles by division of one organelle.
GOC:jid
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
terminal differentiation
GO:0048468
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:go_curators
terminal differentiation
GOC:dph
GOC:tb
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
biological_process
functional differentiation
GO:0048469
cell maturation
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
GOC:go_curators
functional differentiation
GOC:dph
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
GO:0009993
GO:0048157
Wikipedia:Oogenesis
ovum development
biological_process
GO:0048477
oogenesis
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
GOC:kmv
GOC:mtg_sensu
GOC:pr
ovum development
Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.
biological_process
rhythm
GO:0048511
rhythmic process
Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.
GOC:jid
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
circadian rhythm behavior
biological_process
GO:0048512
circadian behavior
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
GOC:bf
GOC:go_curators
GOC:pr
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
Wikipedia:Organogenesis
development of an organ
organogenesis
biological_process
GO:0048513
animal organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GOC:dph
GOC:jid
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
biological_process
GO:0048514
blood vessel morphogenesis
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
GOC:jid
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
spermatid cell differentiation
biological_process
GO:0048515
spermatid differentiation
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GOC:dph
GOC:jid
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0043119
positive regulation of physiological process
up regulation of biological process
up-regulation of biological process
upregulation of biological process
activation of biological process
stimulation of biological process
biological_process
GO:0048518
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0043118
down regulation of biological process
down-regulation of biological process
downregulation of biological process
negative regulation of physiological process
inhibition of biological process
biological_process
GO:0048519
negative regulation of biological process
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:jid
Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
up regulation of behavior
up-regulation of behavior
upregulation of behavior
activation of behavior
stimulation of behavior
biological_process
GO:0048520
positive regulation of behavior
Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GOC:jid
GOC:pr
Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
down regulation of behavior
down-regulation of behavior
downregulation of behavior
inhibition of behavior
biological_process
GO:0048521
negative regulation of behavior
Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GOC:jid
GOC:pr
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051242
positive regulation of cellular physiological process
up regulation of cellular process
up-regulation of cellular process
upregulation of cellular process
activation of cellular process
stimulation of cellular process
biological_process
GO:0048522
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051243
down regulation of cellular process
down-regulation of cellular process
downregulation of cellular process
negative regulation of cellular physiological process
inhibition of cellular process
biological_process
GO:0048523
negative regulation of cellular process
Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:jid
The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
haematopoietic or lymphoid organ development
haemopoietic or lymphoid organ development
hemopoietic or lymphoid organ development
biological_process
GO:0048534
hematopoietic or lymphoid organ development
The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
GOC:add
GOC:rl
ISBN:0781735149
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
response to steroid hormone stimulus
biological_process
GO:0048545
response to steroid hormone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
GOC:go_curators
response to steroid hormone stimulus
GOC:dos
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological_process
GO:0048583
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
up regulation of response to stimulus
up-regulation of response to stimulus
upregulation of response to stimulus
activation of response to stimulus
stimulation of response to stimulus
biological_process
GO:0048584
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
down regulation of response to stimulus
down-regulation of response to stimulus
downregulation of response to stimulus
inhibition of response to stimulus
biological_process
GO:0048585
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
biological_process
GO:0048589
developmental growth
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
GOC:go_curators
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
biological_process
GO:0048599
oocyte development
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GOC:go_curators
The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
organismal reproductive process
reproductive process in a multicellular organism
biological_process
GO:0048609
multicellular organismal reproductive process
The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
GOC:dph
GOC:jid
GOC:tb
Any process that modulates the frequency, rate or extent of developmental growth.
biological_process
GO:0048638
regulation of developmental growth
Any process that modulates the frequency, rate or extent of developmental growth.
GOC:go_curators
Any process that activates, maintains or increases the rate of developmental growth.
up regulation of developmental growth
up-regulation of developmental growth
upregulation of developmental growth
activation of developmental growth
stimulation of developmental growth
biological_process
GO:0048639
positive regulation of developmental growth
Any process that activates, maintains or increases the rate of developmental growth.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.
down regulation of developmental growth
down-regulation of developmental growth
downregulation of developmental growth
inhibition of developmental growth
biological_process
GO:0048640
negative regulation of developmental growth
Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.
GOC:go_curators
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
formation of an anatomical structure involved in morphogenesis
biological_process
GO:0048646
Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.
anatomical structure formation involved in morphogenesis
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GOC:dph
GOC:jid
GOC:tb
formation of an anatomical structure involved in morphogenesis
GOC:dph
GOC:tb
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
biological_process
GO:0048666
neuron development
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GOC:dph
The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
neuron generation
biological_process
GO:0048699
generation of neurons
The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
GOC:nln
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
biological_process
GO:0048731
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GOC:dph
GOC:jid
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
development of an anatomical structure
biological_process
GO:0048856
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO_REF:0000021
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
biological_process
GO:0048869
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GOC:isa_complete
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
cell locomotion
movement of a cell
biological_process
cell movement
GO:0048870
cell motility
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GOC:dgh
GOC:dph
GOC:isa_complete
GOC:mlg
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
cell population homeostasis
homeostasis of cell number
biological_process
GO:0048872
homeostasis of number of cells
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
GOC:isa_complete
homeostasis of cell number
GOC:dph
Any biological process involved in the maintenance of an internal steady state of a chemical.
biological_process
GO:0048878
chemical homeostasis
Any biological process involved in the maintenance of an internal steady state of a chemical.
GOC:isa_complete
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
biological_process
GO:0050673
epithelial cell proliferation
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
ISBN:0721662544
Any process that modulates the frequency, rate or extent of epithelial cell proliferation.
biological_process
GO:0050678
regulation of epithelial cell proliferation
Any process that modulates the frequency, rate or extent of epithelial cell proliferation.
GOC:ai
Any process that activates or increases the rate or extent of epithelial cell proliferation.
up regulation of epithelial cell proliferation
up-regulation of epithelial cell proliferation
upregulation of epithelial cell proliferation
activation of epithelial cell proliferation
stimulation of epithelial cell proliferation
biological_process
GO:0050679
positive regulation of epithelial cell proliferation
Any process that activates or increases the rate or extent of epithelial cell proliferation.
GOC:ai
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
down regulation of epithelial cell proliferation
down-regulation of epithelial cell proliferation
downregulation of epithelial cell proliferation
inhibition of epithelial cell proliferation
biological_process
GO:0050680
negative regulation of epithelial cell proliferation
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
GOC:ai
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
biological_process
GO:0050708
regulation of protein secretion
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
down regulation of protein secretion
down-regulation of protein secretion
downregulation of protein secretion
inhibition of protein secretion
biological_process
GO:0050709
negative regulation of protein secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
up regulation of protein secretion
up-regulation of protein secretion
upregulation of protein secretion
activation of protein secretion
stimulation of protein secretion
biological_process
GO:0050714
positive regulation of protein secretion
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
biological_process
GO:0050727
regulation of inflammatory response
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
GO:0030236
anti-inflammatory response
down regulation of inflammatory response
down-regulation of inflammatory response
downregulation of inflammatory response
inhibition of inflammatory response
biological_process
GO:0050728
negative regulation of inflammatory response
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
up regulation of inflammatory response
up-regulation of inflammatory response
upregulation of inflammatory response
activation of inflammatory response
stimulation of inflammatory response
biological_process
GO:0050729
positive regulation of inflammatory response
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
GOC:ai
Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.
biological_process
GO:0050767
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
down regulation of neurogenesis
down-regulation of neurogenesis
downregulation of neurogenesis
inhibition of neurogenesis
biological_process
GO:0050768
negative regulation of neurogenesis
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
GOC:ai
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
up regulation of neurogenesis
up-regulation of neurogenesis
upregulation of neurogenesis
activation of neurogenesis
stimulation of neurogenesis
biological_process
GO:0050769
positive regulation of neurogenesis
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
GOC:ai
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
biological_process
GO:0050776
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
down regulation of immune response
down-regulation of immune response
downregulation of immune response
inhibition of immune response
biological_process
GO:0050777
negative regulation of immune response
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
up regulation of immune response
up-regulation of immune response
upregulation of immune response
stimulation of immune response
biological_process
GO:0050778
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GOC:ai
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0050791
regulation of physiological process
biological_process
GO:0050789
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:ai
GOC:go_curators
Any process that modulates the activity of an enzyme.
GO:0048552
MIPS_funcat:18.02.01
regulation of enzyme activity
regulation of metalloenzyme activity
biological_process
GO:0050790
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
GOC:ai
GOC:ebc
GOC:vw
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
GO:0050793
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:go_curators
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051244
regulation of cellular physiological process
biological_process
GO:0050794
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:go_curators
Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
regulation of behaviour
biological_process
GO:0050795
regulation of behavior
Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GOC:go_curators
GOC:pr
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
GO:2000021
biological_process
electrolyte homeostasis
negative regulation of crystal formation
regulation of ion homeostasis
GO:0050801
ion homeostasis
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
GOC:ai
The part of the circadian sleep/wake cycle where the organism is asleep.
biological_process
GO:0050802
circadian sleep/wake cycle, sleep
The part of the circadian sleep/wake cycle where the organism is asleep.
GOC:ai
The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
clotting
biological_process
GO:0050817
coagulation
The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
ISBN:0198506732
Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
regulation of clotting
biological_process
GO:0050818
regulation of coagulation
Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
down regulation of coagulation
down-regulation of coagulation
downregulation of coagulation
negative regulation of clotting
inhibition of coagulation
biological_process
anticoagulant activity
GO:0050819
negative regulation of coagulation
Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
GOC:ai
Any process that activates or increases the frequency, rate or extent of coagulation.
positive regulation of clotting
up regulation of coagulation
up-regulation of coagulation
upregulation of coagulation
activation of coagulation
stimulation of coagulation
biological_process
GO:0050820
positive regulation of coagulation
Any process that activates or increases the frequency, rate or extent of coagulation.
GOC:ai
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
biological_process
GO:0050865
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
down regulation of cell activation
down-regulation of cell activation
downregulation of cell activation
inhibition of cell activation
biological_process
GO:0050866
negative regulation of cell activation
Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
GOC:ai
Any process that activates or increases the frequency, rate or extent of activation.
up regulation of cell activation
up-regulation of cell activation
upregulation of cell activation
activation of cell activation
stimulation of cell activation
biological_process
GO:0050867
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
GOC:ai
A organ system process carried out by any of the organs or tissues of neurological system.
https://github.com/geneontology/go-ontology/issues/13824
neurological system process
neurophysiological process
biological_process
pan-neural process
GO:0050877
nervous system process
A organ system process carried out by any of the organs or tissues of neurological system.
GOC:ai
GOC:mtg_cardio
Any process that modulates the levels of body fluids.
biological_process
GO:0050878
regulation of body fluid levels
Any process that modulates the levels of body fluids.
GOC:ai
GOC:dph
GOC:tb
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
Wikipedia:Cognition
biological_process
GO:0050890
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
ISBN:0721619908
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0051869
MIPS_funcat:34.11
physiological response to stimulus
biological_process
GO:0050896
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GOC:ai
GOC:bf
The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.
Wikipedia:Transduction_(physiology)
sensory detection of stimulus
sensory perception, sensory transduction of stimulus
sensory perception, stimulus detection
sensory transduction
biological_process
GO:0050906
detection of stimulus involved in sensory perception
The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.
GOC:ai
GOC:dos
GOC:dph
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
sensory detection of light during visual perception
sensory detection of light stimulus during visual perception
sensory transduction of light during visual perception
sensory transduction of light stimulus during visual perception
visual perception, detection of light stimulus
visual perception, sensory transduction during perception of light
visual perception, sensory transduction of light stimulus
biological_process
GO:0050908
detection of light stimulus involved in visual perception
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
GOC:ai
GOC:dos
The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
Wikipedia:Taste
gustation
sense of taste
taste
taste perception
biological_process
GO:0050909
sensory perception of taste
The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
GOC:ai
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
bitter taste perception
biological_process
GO:0050913
sensory perception of bitter taste
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GOC:ai
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
biological_process
GO:0050953
sensory perception of light stimulus
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GOC:ai
The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
mechanosensory perception
perception of mechanical stimulus
biological_process
chemi-mechanical coupling
GO:0050954
sensory perception of mechanical stimulus
The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GOC:ai
The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.
sensory detection of light stimulus
sensory detection of light stimulus during sensory perception
sensory perception, sensory detection of light stimulus
sensory perception, sensory transduction of light stimulus
sensory transduction of light stimulus
sensory transduction of light stimulus during sensory perception
biological_process
GO:0050962
detection of light stimulus involved in sensory perception
The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.
GOC:ai
GOC:dos
Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.
meiotic regulation of transcription
regulation of transcription, meiotic
biological_process
GO:0051037
regulation of transcription involved in meiotic cell cycle
Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.
GOC:go_curators
regulation of transcription, meiotic
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.
down regulation of transcription during meiosis
down-regulation of transcription during meiosis
downregulation of transcription during meiosis
meiotic repression of transcription
negative regulation of meiotic transcription
negative regulation of transcription, meiotic
inhibition of transcription during meiosis
biological_process
GO:0051038
negative regulation of transcription involved in meiotic cell cycle
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.
GOC:ai
down regulation of transcription during meiosis
GOC:mah
down-regulation of transcription during meiosis
GOC:mah
downregulation of transcription during meiosis
GOC:mah
negative regulation of transcription, meiotic
GOC:mah
inhibition of transcription during meiosis
GOC:mah
Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
positive regulation of meiotic transcription
positive regulation of transcription, meiotic
up regulation of transcription during meiosis
up-regulation of transcription during meiosis
upregulation of transcription during meiosis
activation of transcription during meiosis
stimulation of transcription during meiosis
biological_process
GO:0051039
positive regulation of transcription involved in meiotic cell cycle
Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
GOC:ai
positive regulation of transcription, meiotic
GOC:mah
up regulation of transcription during meiosis
GOC:mah
up-regulation of transcription during meiosis
GOC:mah
upregulation of transcription during meiosis
GOC:mah
activation of transcription during meiosis
GOC:mah
stimulation of transcription during meiosis
GOC:mah
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
biological_process
GO:0051046
regulation of secretion
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
up regulation of secretion
up-regulation of secretion
upregulation of secretion
activation of secretion
stimulation of secretion
biological_process
GO:0051047
positive regulation of secretion
Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
down regulation of secretion
down-regulation of secretion
downregulation of secretion
inhibition of secretion
biological_process
GO:0051048
negative regulation of secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0051049
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of transport
up-regulation of transport
upregulation of transport
activation of transport
stimulation of transport
biological_process
GO:0051050
positive regulation of transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of transport
down-regulation of transport
downregulation of transport
inhibition of transport
biological_process
GO:0051051
negative regulation of transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
regulation of DNA metabolism
biological_process
GO:0051052
regulation of DNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
down regulation of DNA metabolic process
down-regulation of DNA metabolic process
downregulation of DNA metabolic process
negative regulation of DNA metabolism
inhibition of DNA metabolic process
biological_process
GO:0051053
negative regulation of DNA metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of DNA metabolism
up regulation of DNA metabolic process
up-regulation of DNA metabolic process
upregulation of DNA metabolic process
activation of DNA metabolic process
stimulation of DNA metabolic process
biological_process
GO:0051054
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
down regulation of developmental process
down-regulation of developmental process
downregulation of developmental process
inhibition of developmental process
biological_process
GO:0051093
negative regulation of developmental process
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:ai
Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
up regulation of developmental process
up-regulation of developmental process
upregulation of developmental process
activation of developmental process
stimulation of developmental process
biological_process
GO:0051094
positive regulation of developmental process
Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:ai
Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
biological_process
GO:0051098
regulation of binding
Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
up regulation of binding
up-regulation of binding
upregulation of binding
activation of binding
stimulation of binding
biological_process
GO:0051099
positive regulation of binding
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
down regulation of binding
down-regulation of binding
downregulation of binding
inhibition of binding
biological_process
GO:0051100
negative regulation of binding
Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
biological_process
GO:0051101
regulation of DNA binding
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:ai
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
regulation of cellular component organisation
biological_process
regulation of cell organisation
regulation of cell organization
regulation of cellular component organization and biogenesis
GO:0051128
regulation of cellular component organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
regulation of cell organisation
GOC:mah
regulation of cell organization
GOC:mah
regulation of cellular component organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
down regulation of cell organization
down-regulation of cell organization
downregulation of cell organization
inhibition of cell organization
biological_process
negative regulation of cell organisation
negative regulation of cellular component organization and biogenesis
GO:0051129
negative regulation of cellular component organization
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
negative regulation of cell organisation
GOC:mah
negative regulation of cellular component organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
positive regulation of cell organisation
up regulation of cell organization
up-regulation of cell organization
upregulation of cell organization
activation of cell organization
stimulation of cell organization
biological_process
positive regulation of cellular component organization and biogenesis
GO:0051130
positive regulation of cellular component organization
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
positive regulation of cellular component organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
regulation of nitrogen metabolic process
regulation of nitrogen metabolism
biological_process
GO:0051171
regulation of nitrogen compound metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
regulation of nitrogen metabolic process
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
down regulation of nitrogen metabolic process
down-regulation of nitrogen metabolic process
downregulation of nitrogen metabolic process
negative regulation of nitrogen metabolic process
negative regulation of nitrogen metabolism
inhibition of nitrogen metabolic process
biological_process
GO:0051172
negative regulation of nitrogen compound metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
negative regulation of nitrogen metabolic process
GOC:tb
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
positive regulation of nitrogen metabolic process
positive regulation of nitrogen metabolism
up regulation of nitrogen metabolic process
up-regulation of nitrogen metabolic process
upregulation of nitrogen metabolic process
activation of nitrogen metabolic process
stimulation of nitrogen metabolic process
biological_process
GO:0051173
positive regulation of nitrogen compound metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
positive regulation of nitrogen metabolic process
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
regulation of phosphorus metabolism
biological_process
GO:0051174
regulation of phosphorus metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
down regulation of sulfur metabolic process
down-regulation of sulfur metabolic process
downregulation of sulfur metabolic process
negative regulation of sulfur metabolism
negative regulation of sulphur metabolic process
negative regulation of sulphur metabolism
inhibition of sulfur metabolic process
biological_process
GO:0051175
negative regulation of sulfur metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
positive regulation of sulfur metabolism
positive regulation of sulphur metabolic process
positive regulation of sulphur metabolism
up regulation of sulfur metabolic process
up-regulation of sulfur metabolic process
upregulation of sulfur metabolic process
activation of sulfur metabolic process
stimulation of sulfur metabolic process
biological_process
GO:0051176
positive regulation of sulfur metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GOC:ai
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
jl
2013-12-18T13:51:04Z
GO:1902578
establishment and maintenance of localization
establishment and maintenance of position
localisation
establishment and maintenance of cellular component location
establishment and maintenance of substance location
establishment and maintenance of substrate location
biological_process
single organism localization
single-organism localization
GO:0051179
localization
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GOC:ai
GOC:dos
localisation
GOC:mah
single organism localization
GOC:TermGenie
The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
vitamin or cofactor transport
biological_process
GO:0051180
vitamin transport
The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GOC:ai
The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.
vitamin or cofactor transport
biological_process
GO:0051181
cofactor transport
The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.
GOC:ai
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
cofactor metabolism
biological_process
GO:0051186
cofactor metabolic process
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
regulation of cofactor metabolism
biological_process
GO:0051193
regulation of cofactor metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
positive regulation of cofactor metabolism
up regulation of cofactor metabolic process
up-regulation of cofactor metabolic process
upregulation of cofactor metabolic process
activation of cofactor metabolic process
stimulation of cofactor metabolic process
biological_process
GO:0051194
positive regulation of cofactor metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
down regulation of cofactor metabolic process
down-regulation of cofactor metabolic process
downregulation of cofactor metabolic process
negative regulation of cofactor metabolism
inhibition of cofactor metabolic process
biological_process
GO:0051195
negative regulation of cofactor metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
regulation of coenzyme and prosthetic group metabolic process
regulation of coenzyme and prosthetic group metabolism
regulation of coenzyme metabolism
biological_process
GO:0051196
regulation of coenzyme metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
positive regulation of coenzyme and prosthetic group metabolic process
positive regulation of coenzyme and prosthetic group metabolism
positive regulation of coenzyme metabolism
up regulation of coenzyme metabolic process
up-regulation of coenzyme metabolic process
upregulation of coenzyme metabolic process
activation of coenzyme metabolic process
stimulation of coenzyme metabolic process
biological_process
GO:0051197
positive regulation of coenzyme metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
negative regulation of coenzyme and prosthetic group metabolic process
negative regulation of coenzyme and prosthetic group metabolism
down regulation of coenzyme metabolic process
down-regulation of coenzyme metabolic process
downregulation of coenzyme metabolic process
negative regulation of coenzyme metabolism
inhibition of coenzyme metabolic process
biological_process
GO:0051198
negative regulation of coenzyme metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of protein transport
up-regulation of protein transport
upregulation of protein transport
activation of protein transport
stimulation of protein transport
biological_process
GO:0051222
positive regulation of protein transport
Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
GO:0051223
regulation of protein transport
Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of protein transport
down-regulation of protein transport
downregulation of protein transport
inhibition of protein transport
biological_process
GO:0051224
negative regulation of protein transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0051226
GO:0051227
bipolar spindle biosynthesis
bipolar spindle formation
spindle biosynthesis
spindle formation
biological_process
GO:0051225
spindle assembly
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GOC:ai
GOC:expert_rg
GOC:mtg_sensu
GOC:tb
The cell cycle process in which the distance is lengthened between poles of the spindle.
biological_process
GO:0051231
spindle elongation
The cell cycle process in which the distance is lengthened between poles of the spindle.
GOC:ai
The lengthening of the distance between poles of the spindle during a meiotic cell cycle.
spindle elongation during meiosis
biological_process
GO:0051232
meiotic spindle elongation
The lengthening of the distance between poles of the spindle during a meiotic cell cycle.
GOC:ai
Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
establishment of localisation
biological_process
GO:0051234
establishment of localization
Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GOC:ai
GOC:dos
establishment of localisation
GOC:mah
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
biological_process
GO:0051239
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
up regulation of multicellular organismal process
up-regulation of multicellular organismal process
upregulation of multicellular organismal process
activation of multicellular organismal process
stimulation of multicellular organismal process
biological_process
GO:0051240
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
down regulation of multicellular organismal process
down-regulation of multicellular organismal process
downregulation of multicellular organismal process
inhibition of multicellular organismal process
biological_process
GO:0051241
negative regulation of multicellular organismal process
Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
Any process that stops, prevents, or reduces the rate of the cellular defense response.
down regulation of cellular defense response
down-regulation of cellular defense response
downregulation of cellular defense response
negative regulation of cellular defence response
inhibition of cellular defense response
biological_process
GO:0051245
negative regulation of cellular defense response
Any process that stops, prevents, or reduces the rate of the cellular defense response.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
regulation of protein metabolism
biological_process
GO:0051246
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolism
up regulation of protein metabolic process
up-regulation of protein metabolic process
upregulation of protein metabolic process
activation of protein metabolic process
stimulation of protein metabolic process
biological_process
GO:0051247
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
down regulation of protein metabolic process
down-regulation of protein metabolic process
downregulation of protein metabolic process
negative regulation of protein metabolism
inhibition of protein metabolic process
biological_process
GO:0051248
negative regulation of protein metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
GOC:ai
Any process that modulates the frequency, rate or extent of lymphocyte activation.
biological_process
GO:0051249
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.
down regulation of lymphocyte activation
down-regulation of lymphocyte activation
downregulation of lymphocyte activation
inhibition of lymphocyte activation
biological_process
GO:0051250
negative regulation of lymphocyte activation
Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.
GOC:ai
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
up regulation of lymphocyte activation
up-regulation of lymphocyte activation
upregulation of lymphocyte activation
activation of lymphocyte activation
stimulation of lymphocyte activation
biological_process
GO:0051251
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
regulation of RNA metabolism
biological_process
GO:0051252
regulation of RNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
down regulation of RNA metabolic process
down-regulation of RNA metabolic process
downregulation of RNA metabolic process
negative regulation of RNA metabolism
inhibition of RNA metabolic process
biological_process
GO:0051253
negative regulation of RNA metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
positive regulation of RNA metabolism
up regulation of RNA metabolic process
up-regulation of RNA metabolic process
upregulation of RNA metabolic process
activation of RNA metabolic process
stimulation of RNA metabolic process
biological_process
GO:0051254
positive regulation of RNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
regulation of cellular component motion
biological_process
regulation of cell movement
GO:0051270
regulation of cellular component movement
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
regulation of cellular component motion
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.
negative regulation of cellular component motion
biological_process
GO:0051271
negative regulation of cellular component movement
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
negative regulation of cellular component motion
GOC:mah
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
positive regulation of cellular component motion
biological_process
GO:0051272
positive regulation of cellular component movement
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
positive regulation of cellular component motion
GOC:mah
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0007001
GO:0051277
chromosome organisation
biological_process
chromosome organization and biogenesis
maintenance of genome integrity
nuclear genome maintenance
GO:0051276
chromosome organization
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
chromosome organization and biogenesis
GOC:mah
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
Wikipedia:Cell_division
biological_process
GO:0051301
Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.
cell division
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
GOC:di
GOC:go_curators
GOC:pr
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
biological_process
GO:0051302
regulation of cell division
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
GOC:go_curators
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
Wikipedia:G1_phase
biological_process
GO:0051318
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
G1 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
GOC:mtg_cell_cycle
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
Wikipedia:G2_phase
biological_process
GO:0051319
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
G2 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
GOC:mtg_cell_cycle
The cell cycle phase, following G1, during which DNA synthesis takes place.
Wikipedia:S_phase
S-phase
biological_process
GO:0051320
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
S phase
The cell cycle phase, following G1, during which DNA synthesis takes place.
GOC:mtg_cell_cycle
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
GO:0007126
Wikipedia:Meiosis
biological_process
meiosis
GO:0051321
meiotic cell cycle
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
GOC:ai
The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
Wikipedia:Anaphase
biological_process
GO:0051322
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
anaphase
The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
GOC:mtg_cell_cycle
The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
Wikipedia:Metaphase
biological_process
GO:0051323
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
metaphase
The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
GOC:mtg_cell_cycle
The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
Wikipedia:Prophase
biological_process
GO:0051324
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
prophase
The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GOC:mtg_cell_cycle
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
resting phase
Wikipedia:Interphase
karyostasis
biological_process
GO:0051325
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
interphase
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
GOC:mtg_cell_cycle
The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
Wikipedia:Telophase
biological_process
GO:0051326
note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
telophase
The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GOC:mtg_cell_cycle
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
M phase of meiotic cell cycle
biological_process
GO:0051327
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic M phase
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
GOC:mtg_cell_cycle
The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
interphase of meiotic cell cycle
biological_process
GO:0051328
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic interphase
The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
GOC:mtg_cell_cycle
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
interphase of mitotic cell cycle
biological_process
GO:0051329
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic interphase
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
GOC:mtg_cell_cycle
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.
G1 phase of meiotic cell cycle
biological_process
GO:0051330
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic G1 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.
GOC:mtg_cell_cycle
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.
G2 phase of meiotic cell cycle
biological_process
GO:0051331
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic G2 phase
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.
GOC:mtg_cell_cycle
The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.
S phase of meiotic cell cycle
S-phase of meiotic cell cycle
biological_process
GO:0051332
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic S phase
The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.
GOC:mtg_cell_cycle
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
hydrolase regulator
biological_process
GO:0051336
regulation of hydrolase activity
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
EC:3.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
transferase regulator
biological_process
GO:0051338
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
EC:2.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
ligase regulator
biological_process
GO:0051340
regulation of ligase activity
Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
EC:6.-.-.-
GOC:ai
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
hydrolase activator
up regulation of hydrolase activity
up-regulation of hydrolase activity
upregulation of hydrolase activity
activation of hydrolase activity
stimulation of hydrolase activity
biological_process
GO:0051345
positive regulation of hydrolase activity
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GOC:ai
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
down regulation of hydrolase activity
down-regulation of hydrolase activity
downregulation of hydrolase activity
hydrolase inhibitor
inhibition of hydrolase activity
biological_process
GO:0051346
negative regulation of hydrolase activity
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GOC:ai
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
transferase activator
up regulation of transferase activity
up-regulation of transferase activity
upregulation of transferase activity
activation of transferase activity
stimulation of transferase activity
biological_process
GO:0051347
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
down regulation of transferase activity
down-regulation of transferase activity
downregulation of transferase activity
transferase inhibitor
inhibition of transferase activity
biological_process
GO:0051348
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
negative regulation of transferase activity
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
ligase activator
up regulation of ligase activity
up-regulation of ligase activity
upregulation of ligase activity
activation of ligase activity
stimulation of ligase activity
biological_process
GO:0051351
positive regulation of ligase activity
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GOC:ai
Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
down regulation of ligase activity
down-regulation of ligase activity
downregulation of ligase activity
ligase inhibitor
inhibition of ligase activity
biological_process
GO:0051352
negative regulation of ligase activity
Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GOC:ai
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
response to glucocorticoid stimulus
biological_process
GO:0051384
response to glucocorticoid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
GOC:ai
PMID:9884123
response to glucocorticoid stimulus
GOC:dos
Interacting selectively and non-covalently with a receptor for hormones.
molecular_function
GO:0051427
hormone receptor binding
Interacting selectively and non-covalently with a receptor for hormones.
GOC:ai
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
meiotic cell cycle modulation
meiotic cell cycle regulation
modulation of meiotic cell cycle progression
regulation of meiotic cell cycle progression
regulation of progression through meiotic cell cycle
biological_process
meiotic cell cycle regulator
GO:0051445
regulation of meiotic cell cycle
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
GOC:ai
GOC:dph
GOC:tb
regulation of progression through meiotic cell cycle
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
positive regulation of meiotic cell cycle progression
positive regulation of progression through meiotic cell cycle
up regulation of progression through meiotic cell cycle
up-regulation of progression through meiotic cell cycle
upregulation of progression through meiotic cell cycle
activation of progression through meiotic cell cycle
stimulation of progression through meiotic cell cycle
biological_process
GO:0051446
positive regulation of meiotic cell cycle
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
GOC:ai
GOC:dph
GOC:tb
positive regulation of progression through meiotic cell cycle
GOC:dph
GOC:tb
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
down regulation of progression through meiotic cell cycle
down-regulation of progression through meiotic cell cycle
downregulation of progression through meiotic cell cycle
negative regulation of meiotic cell cycle progression
negative regulation of progression through meiotic cell cycle
inhibition of progression through meiotic cell cycle
biological_process
GO:0051447
negative regulation of meiotic cell cycle
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
GOC:ai
GOC:dph
GOC:tb
negative regulation of progression through meiotic cell cycle
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
regulation of cytoskeleton organisation
biological_process
regulation of cytoskeleton organization and biogenesis
GO:0051493
regulation of cytoskeleton organization
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
regulation of cytoskeleton organisation
GOC:mah
regulation of cytoskeleton organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
down regulation of cytoskeleton organization
down-regulation of cytoskeleton organization
downregulation of cytoskeleton organization
negative regulation of cytoskeleton organisation
inhibition of cytoskeleton organization
biological_process
negative regulation of cytoskeleton organization and biogenesis
GO:0051494
negative regulation of cytoskeleton organization
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
negative regulation of cytoskeleton organisation
GOC:mah
negative regulation of cytoskeleton organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
positive regulation of cytoskeleton organisation
up regulation of cytoskeleton organization
up-regulation of cytoskeleton organization
upregulation of cytoskeleton organization
activation of cytoskeleton organization
stimulation of cytoskeleton organization
biological_process
positive regulation of cytoskeleton organization and biogenesis
GO:0051495
positive regulation of cytoskeleton organization
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
positive regulation of cytoskeleton organisation
GOC:mah
positive regulation of cytoskeleton organization and biogenesis
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
calcium ion homeostasis in mitochondria
calcium ion homeostasis in mitochondrion
mitochondrial calcium ion concentration regulation
regulation of calcium ion concentration in mitochondria
regulation of calcium ion concentration in mitochondrion
regulation of mitochondrial calcium ion concentration
biological_process
GO:0051560
mitochondrial calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
GOC:ai
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.
calcium ion homeostasis in smooth ER
calcium ion homeostasis in smooth endoplasmic reticulum
regulation of calcium ion concentration in smooth ER
regulation of calcium ion concentration in smooth endoplasmic reticulum
regulation of smooth ER calcium ion concentration
regulation of smooth endoplasmic reticulum calcium ion concentration
smooth ER calcium ion concentration regulation
smooth ER calcium ion homeostasis
smooth endoplasmic reticulum calcium ion concentration regulation
biological_process
GO:0051563
smooth endoplasmic reticulum calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.
GOC:ai
GOC:mah
The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
stimulus detection
biological_process
perception of stimulus
stimulus sensing
GO:0051606
detection of stimulus
The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
GOC:add
GOC:ai
GOC:dph
GOC:mah
Any process in which an organelle is transported to, and/or maintained in, a specific location.
establishment and maintenance of organelle localization
organelle localisation
biological_process
GO:0051640
organelle localization
Any process in which an organelle is transported to, and/or maintained in, a specific location.
GOC:ai
organelle localisation
GOC:mah
A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
jl
2013-12-18T14:04:32Z
GO:1902580
cellular localisation
establishment and maintenance of cellular localization
establishment and maintenance of localization in cell or cell membrane
single organism cellular localization
intracellular localization
localization within cell
biological_process
single-organism cellular localization
GO:0051641
cellular localization
A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GOC:tb
GOC:vw
cellular localisation
GOC:mah
single organism cellular localization
GOC:TermGenie
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
establishment and maintenance of mitochondria localization
establishment and maintenance of mitochondrion localization
localization of mitochondria
localization of mitochondrion
mitochondria localization
mitochondrial localization
mitochondrion localisation
biological_process
GO:0051646
mitochondrion localization
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
GOC:ai
mitochondrion localisation
GOC:mah
Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
cytoplasmic vesicle localization
establishment and maintenance of vesicle localization
vesicle localisation
biological_process
GO:0051648
vesicle localization
Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
GOC:ai
vesicle localisation
GOC:mah
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
establishment of localisation in cell
establishment of intracellular localization
establishment of localization within cell
positioning within cell
biological_process
establishment of cellular localization
GO:0051649
establishment of localization in cell
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GOC:ai
GOC:dos
GOC:dph
GOC:tb
establishment of localisation in cell
GOC:mah
establishment of cellular localization
GOC:dph
GOC:tb
The directed movement of a vesicle to a specific location.
establishment of vesicle localisation
biological_process
GO:0051650
establishment of vesicle localization
The directed movement of a vesicle to a specific location.
GOC:ai
establishment of vesicle localisation
GOC:mah
The directed movement of an organelle to a specific location.
establishment of organelle localisation
biological_process
GO:0051656
establishment of organelle localization
The directed movement of an organelle to a specific location.
GOC:ai
establishment of organelle localisation
GOC:mah
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
establishment and maintenance of localization in membrane
establishment and maintenance of position in membrane
localisation within membrane
localization to membrane
positioning within membrane
biological_process
GO:0051668
localization within membrane
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
GOC:ai
localisation within membrane
GOC:mah
Any process in which a cell is transported to, and/or maintained in, a specific location.
cell localization
establishment and maintenance of cell localization
establishment and maintenance of localization of cell
localisation of cell
biological_process
GO:0051674
localization of cell
Any process in which a cell is transported to, and/or maintained in, a specific location.
GOC:ai
localisation of cell
GOC:mah
An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
biological_process
GO:0051701
interaction with host
An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
GOC:cc
Any process in which an organism has an effect on an organism of the same species.
intraspecies interaction with other organisms
biological_process
GO:0051703
intraspecies interaction between organisms
Any process in which an organism has an effect on an organism of the same species.
GOC:ai
A biological process which involves another organism of the same or different species.
GO:0051706
interaction between organisms
physiological interaction between organisms
physiological interaction with other organism
biological_process
GO:0051704
multi-organism process
A biological process which involves another organism of the same or different species.
GOC:jl
OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species.
https://github.com/geneontology/go-ontology/issues/18810
behavioral interaction between organisms
behavioral interaction with other organism
behavioural interaction between organisms
behavioural interaction with other organism
behavioral signaling
behavioral signalling
biological_process
GO:0051705
This term was obsoleted because it was an unnecessary grouping term.
multi-organism behavior
obsolete multi-organism behavior
true
OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species.
GOC:ai
behavioral signalling
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
GO:0009613
GO:0042828
biological_process
GO:0051707
response to other organism
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
GOC:ai
true
Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.
regulation of killing of cells of another organism
biological_process
GO:0051709
regulation of killing of cells of other organism
Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.
GOC:ai
regulation of killing of cells of another organism
GOC:bf
Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.
down regulation of killing of cells of another organism
down-regulation of killing of cells of another organism
downregulation of killing of cells of another organism
negative regulation of killing of cells of another organism
inhibition of killing of cells of another organism
biological_process
GO:0051711
negative regulation of killing of cells of other organism
Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.
GOC:ai
negative regulation of killing of cells of another organism
GOC:bf
Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.
up regulation of killing of cells of another organism
up-regulation of killing of cells of another organism
upregulation of killing of cells of another organism
activation of killing of cells of another organism
stimulation of killing of cells of another organism
biological_process
GO:0051712
positive regulation of killing of cells of other organism
Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.
GOC:ai
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
biological_process
GO:0051716
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GOC:bf
GOC:jl
Any process that modulates the rate or extent of progression through the cell cycle.
GO:0000074
cell cycle modulation
cell cycle regulation
control of cell cycle progression
modulation of cell cycle progression
regulation of cell cycle progression
regulation of progression through cell cycle
biological_process
cell cycle regulator
tumor suppressor
GO:0051726
regulation of cell cycle
Any process that modulates the rate or extent of progression through the cell cycle.
GOC:ai
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of cell division.
up regulation of cell division
up-regulation of cell division
upregulation of cell division
activation of cell division
stimulation of cell division
biological_process
GO:0051781
positive regulation of cell division
Any process that activates or increases the frequency, rate or extent of cell division.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
down regulation of cell division
down-regulation of cell division
downregulation of cell division
inhibition of cell division
biological_process
GO:0051782
negative regulation of cell division
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
GOC:ai
Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
biological_process
GO:0051783
regulation of nuclear division
Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
down regulation of nuclear division
down-regulation of nuclear division
downregulation of nuclear division
inhibition of nuclear division
biological_process
GO:0051784
negative regulation of nuclear division
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
up regulation of nuclear division
up-regulation of nuclear division
upregulation of nuclear division
activation of nuclear division
stimulation of nuclear division
biological_process
GO:0051785
positive regulation of nuclear division
Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.
https://github.com/geneontology/go-ontology/issues/18605
regulation of morphology of other organism during symbiotic interaction
regulation of physiological process in other organism during symbiotic interaction
regulation of physiology of other organism during symbiotic interaction
biological_process
modification of morphology or physiology of other organism during symbiotic interaction
modification of morphology or physiology of other organism involved in symbiotic interaction
modulation of biological process of other organism involved in symbiotic interaction
modulation of morphology or physiology of other organism during symbiotic interaction
regulation of morphology or physiology of other organism during symbiotic interaction
GO:0051817
modulation of process of other organism involved in symbiotic interaction
The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.
GOC:cc
modification of morphology or physiology of other organism during symbiotic interaction
GOC:dph
A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.
biological_process
disruption of cells of other organism during symbiotic interaction
GO:0051818
disruption of cells of other organism involved in symbiotic interaction
A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.
GOC:cc
disruption of cells of other organism during symbiotic interaction
GOC:tb
Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.
biological_process
killing of cells in other organism during symbiotic interaction
GO:0051883
killing of cells in other organism involved in symbiotic interaction
Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.
GOC:add
killing of cells in other organism during symbiotic interaction
GOC:tb
Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
biological_process
GO:0051930
regulation of sensory perception of pain
Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GOC:ai
Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
biological_process
GO:0051931
regulation of sensory perception
Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GOC:ai
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
biological_process
GO:0051960
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
down regulation of nervous system development
down-regulation of nervous system development
downregulation of nervous system development
inhibition of nervous system development
biological_process
GO:0051961
negative regulation of nervous system development
Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
up regulation of nervous system development
up-regulation of nervous system development
upregulation of nervous system development
activation of nervous system development
stimulation of nervous system development
biological_process
GO:0051962
positive regulation of nervous system development
Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
biological_process
GO:0051983
regulation of chromosome segregation
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
up regulation of chromosome segregation
up-regulation of chromosome segregation
upregulation of chromosome segregation
activation of chromosome segregation
stimulation of chromosome segregation
biological_process
GO:0051984
positive regulation of chromosome segregation
Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
down regulation of chromosome segregation
down-regulation of chromosome segregation
downregulation of chromosome segregation
inhibition of chromosome segregation
biological_process
GO:0051985
negative regulation of chromosome segregation
Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modulation of host intracellular trafficking
biological_process
GO:0052038
modulation by symbiont of host intracellular transport
Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052152
modulation of host PCD
modulation by symbiont of host non-apoptotic programmed cell death
biological_process
GO:0052040
modulation by symbiont of host programmed cell death
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation by symbiont of host programmed cell death
down-regulation by symbiont of host programmed cell death
downregulation by symbiont of host programmed cell death
inhibition of host programmed cell death
suppression by symbiont of host PCD
suppression by symbiont of host programmed cell death
inhibition by symbiont of host programmed cell death
biological_process
GO:0052041
negative regulation by symbiont of host programmed cell death
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0012504
GO:0052044
GO:0052045
GO:0052153
GO:0052397
GO:0052400
activation by organism of host programmed cell death
activation by organism of programmed cell death in other organism during symbiotic interaction
enhancement of host programmed cell death
enhancement of host programmed cell death by organism
induction by organism of programmed cell death in other organism involved in symbiotic interaction
induction by symbiont of host programmed cell death
upregulation by symbiont of host programmed cell death
activation by organism of non-apoptotic programmed cell death in other organism
activation by symbiont of host programmed cell death
induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction
positive regulation by symbiont of host non-apoptotic programmed cell death
stimulation by symbiont of host programmed cell death
biological_process
induction by organism of programmed cell death in other organism during symbiotic interaction
induction of non-apoptotic programmed cell death by other organism
GO:0052042
positive regulation by symbiont of host programmed cell death
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:jl
GOC:mtg_pamgo_17jul06
induction by organism of programmed cell death in other organism during symbiotic interaction
GOC:dph
OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction.
biological_process
interaction with other organism via secreted substance during symbiotic interaction
interaction with other organism via secreted substance involved in symbiotic interaction
GO:0052047
This term was obsoleted because it has been misused to annotate host proteins.
obsolete symbiotic process mediated by secreted substance
true
OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
interaction with other organism via secreted substance during symbiotic interaction
GOC:dph
OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
interaction with host via secreted substance during symbiotic interaction
interaction with host via secreted substance involved in symbiotic interaction
GO:0052048
This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.
obsolete interaction with host via secreted substance
true
OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
interaction with host via secreted substance during symbiotic interaction
GOC:dph
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation by symbiont of host enzyme activity
down-regulation by symbiont of host enzyme activity
downregulation by symbiont of host enzyme activity
inhibition of host enzyme activity
negative regulation by symbiont of host enzyme activity
inhibition by symbiont of host enzyme activity
biological_process
GO:0052053
negative regulation by symbiont of host catalytic activity
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation by symbiont of host protease activity
down-regulation by symbiont of host protease activity
downregulation by symbiont of host protease activity
inhibition by symbiont of host protease activity
inhibition of host protease activity
negative regulation by symbiont of host protease activity
biological_process
GO:0052054
negative regulation by symbiont of host peptidase activity
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
negative regulation by symbiont of host protease activity
GOC:dph
GOC:tb
The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modification by symbiont of host molecular function
modification by symbiont of host protein function
biological_process
GO:0052055
modulation by symbiont of host molecular function
The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
modification by symbiont of host protein function
GOC:dph
GOC:tb
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation by symbiont of host protein function
down-regulation by symbiont of host protein function
downregulation by symbiont of host protein function
inhibition of host protein function
negative regulation by symbiont of host protein function
inhibition by symbiont of host protein function
biological_process
GO:0052056
negative regulation by symbiont of host molecular function
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
negative regulation by symbiont of host protein function
GOC:dph
GOC:tb
OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules.
biological_process
GO:0052097
The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete interspecies quorum sensing
true
OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules.
GOC:mtg_pamgo_17jul06
OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.
biological_process
GO:0052100
The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete intraspecies quorum sensing
true
OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.
GOC:mtg_pamgo_17jul06
OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
quorum sensing during interaction with host
GO:0052106
The reason for obsoletion is that this term was not clearly defined and usage was inconsistent.
obsolete quorum sensing involved in interaction with host
true
OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
quorum sensing during interaction with host
GOC:tb
The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
biological_process
GO:0052128
positive energy taxis
The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
GOC:mtg_pamgo_17jul06
The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
biological_process
GO:0052129
negative energy taxis
The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
GOC:mtg_pamgo_17jul06
The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modulation by symbiont of host enzyme activity
modulation of catalytic activity of host by symbiont
regulation by symbiont of host catalytic activity
regulation of catalytic activity of host by symbiont
regulation of host catalytic activity by symbiont
biological_process
GO:0052148
modulation by symbiont of host catalytic activity
The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
GOC:tb
modulation by symbiont of host enzyme activity
GOC:tb
The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modulation by symbiont of host protease activity
biological_process
GO:0052149
modulation by symbiont of host peptidase activity
The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
modulation by symbiont of host protease activity
GOC:bf
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
modulation by organism of host apoptotic programmed cell death
modulation by symbiont of host apoptosis
biological_process
GO:0052150
Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'regulation of apoptosis ; GO:0042981'.
modulation by symbiont of host apoptotic process
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033669
GO:0052030
activation by organism of host apoptosis
activation by organism of host apoptotic programmed cell death
induction by organism of host apoptotic programmed cell death
induction by symbiont of host apoptosis
positive regulation by organism of host apoptotic programmed cell death
up regulation by organism of host apoptotic programmed cell death
up regulation by symbiont of host apoptosis
up-regulation by organism of host apoptotic programmed cell death
up-regulation by symbiont of host apoptosis
upregulation by organism of host apoptotic programmed cell death
upregulation by symbiont of host apoptosis
activation by symbiont of host apoptosis
positive regulation by symbiont of host apoptosis
stimulation by symbiont of host apoptosis
biological_process
GO:0052151
Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of apoptosis ; GO:0043065'.
positive regulation by symbiont of host apoptotic process
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:jl
GOC:mtg_pamgo_17jul06
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
down regulation of protease activity in other organism during symbiotic interaction
down-regulation of protease activity in other organism during symbiotic interaction
downregulation of protease activity in other organism during symbiotic interaction
negative regulation of protease activity in other organism during symbiotic interaction
inhibition of protease activity in other organism during symbiotic interaction
biological_process
GO:0052180
negative regulation of peptidase activity in other organism involved in symbiotic interaction
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
negative regulation of protease activity in other organism during symbiotic interaction
GOC:dph
GOC:tb
The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
modulation of protease activity in other organism involved in symbiotic interaction
biological_process
modulation of protease activity in other organism during symbiotic interaction
GO:0052198
modulation of peptidase activity in other organism involved in symbiotic interaction
The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
modulation of protease activity in other organism involved in symbiotic interaction
GOC:bf
modulation of protease activity in other organism during symbiotic interaction
GOC:dph
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
inhibition of enzyme activity in other organism
negative regulation of enzyme activity in other organism during symbiotic interaction
inhibition of enzyme activity in other organism during symbiotic interaction
biological_process
down regulation of enzyme activity in other organism during symbiotic interaction
down-regulation of enzyme activity in other organism during symbiotic interaction
downregulation of enzyme activity in other organism during symbiotic interaction
GO:0052199
negative regulation of catalytic activity in other organism involved in symbiotic interaction
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
GOC:tb
negative regulation of enzyme activity in other organism during symbiotic interaction
GOC:tb
The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
modulation of enzyme activity within other organism during symbiotic interaction
biological_process
GO:0052203
modulation of catalytic activity in other organism involved in symbiotic interaction
The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
GOC:tb
modulation of enzyme activity within other organism during symbiotic interaction
GOC:tb
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction.
down regulation of protein function in other organism during symbiotic interaction
down-regulation of protein function in other organism during symbiotic interaction
downregulation of protein function in other organism during symbiotic interaction
inhibition of protein function in other organism
negative regulation of protein function in other organism during symbiotic interaction
inhibition of protein function in other organism during symbiotic interaction
biological_process
GO:0052204
negative regulation of molecular function in other organism involved in symbiotic interaction
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
negative regulation of protein function in other organism during symbiotic interaction
GOC:dph
GOC:tb
The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction.
modification of molecular function in other organism during symbiotic interaction
modification of protein function in other organism during symbiotic interaction
biological_process
modulation of molecular function in other organism during symbiotic interaction
GO:0052205
modulation of molecular function in other organism involved in symbiotic interaction
The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction.
GOC:dph
GOC:mtg_pamgo_17jul06
GOC:tb
modification of protein function in other organism during symbiotic interaction
GOC:dph
GOC:tb
modulation of molecular function in other organism during symbiotic interaction
GOC:dph
Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction.
modulation of intracellular trafficking in other organism
biological_process
modulation of intracellular transport in other organism during symbiotic interaction
GO:0052230
modulation of intracellular transport in other organism involved in symbiotic interaction
Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
modulation of intracellular transport in other organism during symbiotic interaction
GOC:dph
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
GO:0052459
modulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction
biological_process
modulation of programmed cell death in other organism during symbiotic interaction
GO:0052248
modulation of programmed cell death in other organism involved in symbiotic interaction
Any process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
GOC:mtg_pamgo_17jul06
modulation of programmed cell death in other organism during symbiotic interaction
GOC:dph
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
GO:0052518
GO:0052529
upregulation by organism of programmed cell death in other organism involved in symbiotic interaction
activation by organism of programmed cell death in other organism during symbiotic interaction
positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction
stimulation by organism of programmed cell death in other organism during symbiotic interaction
biological_process
enhancement of other organism programmed cell death by organism
positive regulation by organism of programmed cell death in other organism during symbiotic interaction
upregulation by organism of programmed cell death in other organism during symbiotic interaction
GO:0052330
positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction
Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
GOC:jl
GOC:mtg_pamgo_17jul06
positive regulation by organism of programmed cell death in other organism during symbiotic interaction
GOC:tb
upregulation by organism of programmed cell death in other organism during symbiotic interaction
GOC:tb
Any process in which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction.
modulation by organism of apoptotic programmed cell death in other organism during symbiotic interaction
modulation by organism of apoptosis in other organism involved in symbiotic interaction
biological_process
modulation by organism of apoptosis in other organism during symbiotic interaction
GO:0052433
modulation by organism of apoptotic process in other organism involved in symbiotic interaction
Any process in which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction.
GOC:jl
GOC:mtg_pamgo_17jul06
modulation by organism of apoptosis in other organism during symbiotic interaction
GOC:dph
Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
biological_process
peptidase regulator activity
GO:0052547
regulation of peptidase activity
Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:ai
Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
biological_process
GO:0055062
phosphate ion homeostasis
Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
GOC:jid
GOC:mah
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
biological_process
GO:0055065
metal ion homeostasis
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
GOC:ai
GOC:jid
GOC:mah
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
zinc homeostasis
biological_process
GO:0055069
zinc ion homeostasis
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
GOC:ai
GOC:jid
GOC:mah
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
regulation of calcium ion concentration
biological_process
GO:0055074
calcium ion homeostasis
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
GOC:ceb
GOC:jid
GOC:mah
Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
biological_process
GO:0055076
transition metal ion homeostasis
Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
GOC:jid
GOC:mah
ISBN:0198506732
Any process involved in the maintenance of an internal steady state of cations within an organism or cell.
biological_process
GO:0055080
cation homeostasis
Any process involved in the maintenance of an internal steady state of cations within an organism or cell.
GOC:ceb
GOC:jid
GOC:mah
Any process involved in the maintenance of an internal steady state of anions within an organism or cell.
biological_process
GO:0055081
anion homeostasis
Any process involved in the maintenance of an internal steady state of anions within an organism or cell.
GOC:ceb
GOC:jid
GOC:mah
Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.
biological_process
GO:0055082
cellular chemical homeostasis
Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.
GOC:isa_complete
GOC:jid
Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.
biological_process
GO:0055083
monovalent inorganic anion homeostasis
Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.
GOC:ai
GOC:jid
GOC:mah
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
tanyaberardini
2015-10-21T13:22:47Z
GO:0090662
membrane transport
ATP hydrolysis coupled transmembrane transport
biological_process
GO:0055085
Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.
transmembrane transport
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
GOC:dph
GOC:jid
The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
nucleobase, nucleoside and nucleotide metabolism
biological_process
nucleobase, nucleoside and nucleotide metabolic process
GO:0055086
nucleobase-containing small molecule metabolic process
The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GOC:vw
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
biological_process
GO:0055122
response to very low light intensity stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
GOC:mtg_far_red
Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
regulation of protein amino acid glycosylation
biological_process
GO:0060049
regulation of protein glycosylation
Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GOC:dms
GOC:dph
GOC:pr
regulation of protein amino acid glycosylation
GOC:bf
Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
positive regulation of protein amino acid glycosylation
biological_process
GO:0060050
positive regulation of protein glycosylation
Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GOC:dms
GOC:dph
GOC:pr
positive regulation of protein amino acid glycosylation
GOC:bf
Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
negative regulation of protein amino acid glycosylation
biological_process
GO:0060051
negative regulation of protein glycosylation
Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GOC:dms
GOC:dph
GOC:pr
negative regulation of protein amino acid glycosylation
GOC:bf
Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
biological_process
GO:0060054
positive regulation of epithelial cell proliferation involved in wound healing
Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
GOC:dph
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
biological_process
GO:0060055
angiogenesis involved in wound healing
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
GOC:dph
PMID:15039218
The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
Wikipedia:Urination
urination
urine voiding
biological_process
GO:0060073
micturition
The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
GOC:dph
A compound molecular function in which an effector function is controlled by one or more regulatory components.
molecular_function
GO:0060089
molecular transducer activity
A compound molecular function in which an effector function is controlled by one or more regulatory components.
GOC:dos
GOC:pdt
Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
biological_process
GO:0060147
regulation of posttranscriptional gene silencing
Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GOC:dph
Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
biological_process
GO:0060148
positive regulation of posttranscriptional gene silencing
Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GOC:dph
Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
biological_process
GO:0060149
negative regulation of posttranscriptional gene silencing
Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GOC:dph
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
regulation of mitotic spindle organisation
biological_process
regulation of mitotic spindle organization and biogenesis
GO:0060236
regulation of mitotic spindle organization
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of mitotic spindle organisation
GOC:mah
regulation of mitotic spindle organization and biogenesis
GOC:mah
The series of events in which information about the density of cells in a population is received and converted into a molecular signal.
biological_process
GO:0060245
detection of cell density
The series of events in which information about the density of cells in a population is received and converted into a molecular signal.
GOC:dph
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
GO:0060255
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
regulation of feeding behaviour
biological_process
GO:0060259
regulation of feeding behavior
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
GOC:BHF
GOC:dph
GOC:tb
regulation of feeding behaviour
GOC:dph
GOC:tb
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0042384
Reactome:R-HSA-5617833.2
ciliogenesis
cilium assembly
cilium formation
microtubule-based flagellum assembly
biological_process
cilium biogenesis
cilium morphogenesis
cilium organization
GO:0060271
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium assembly
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:BHF
GOC:cilia
GOC:dph
GOC:kmv
GOC:pr
GOC:vw
ISBN:0198506732
PMID:13978319
PMID:27350441
Reactome:R-HSA-5617833.2
cilium biogenesis
GOC:mah
cilium organization
GOC:dph
Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
biological_process
GO:0060278
regulation of ovulation
Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GOC:dph
GOC:kmv
GOC:tb
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
biological_process
GO:0060279
positive regulation of ovulation
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GOC:dph
GOC:kmv
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
biological_process
GO:0060280
negative regulation of ovulation
Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GOC:dph
GOC:kmv
GOC:tb
Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
biological_process
GO:0060281
regulation of oocyte development
Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GOC:dph
GOC:tb
PMID:2394318
Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
biological_process
GO:0060282
positive regulation of oocyte development
Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GOC:dph
GOC:tb
Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
biological_process
GO:0060283
negative regulation of oocyte development
Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
GO:0060284
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:dph
GOC:tb
Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0071974
cilium cell motility
microtubule-based flagellar cell motility
biological_process
ciliary cell motility
GO:0060285
Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.
cilium-dependent cell motility
Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:cilia
GOC:dgh
GOC:dph
GOC:krc
GOC:mlg
GOC:mtg_cambridge_2013
Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
biological_process
GO:0060294
cilium movement involved in cell motility
Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
GOC:BHF
GOC:dph
GOC:tb
Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.
biological_process
GO:0060295
regulation of cilium movement involved in cell motility
Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.
GOC:BHF
GOC:dph
GOC:tb
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
biological_process
GO:0060322
head development
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
GOC:dph
Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
regulation of cellular localisation
biological_process
GO:0060341
regulation of cellular localization
Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
GOC:dph
GOC:tb
regulation of cellular localisation
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.
biological_process
GO:0060359
response to ammonium ion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
biological_process
GO:0060467
negative regulation of fertilization
Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GOC:dph
Any process that modulates the rate, frequency, or extent of cell projection assembly.
biological_process
regulation of cell projection formation
GO:0060491
regulation of cell projection assembly
Any process that modulates the rate, frequency, or extent of cell projection assembly.
GOC:dph
GOC:tb
regulation of cell projection formation
GOC:dph
GOC:tb
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
dph
2009-04-13T01:56:10Z
biological_process
GO:0060548
negative regulation of cell death
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:BHF
GOC:dph
GOC:tb
The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.
dph
2009-04-28T08:42:53Z
differential growth
biological_process
GO:0060560
developmental growth involved in morphogenesis
The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.
GOC:dph
differential growth
GOC:dph
Any apoptotic process that contributes to the shaping of an anatomical structure.
dph
2009-04-28T09:17:27Z
apoptosis involved in morphogenesis
biological_process
apoptosis involved in development
morphogenetic apoptosis
GO:0060561
apoptotic process involved in morphogenesis
Any apoptotic process that contributes to the shaping of an anatomical structure.
GOC:dph
GOC:mtg_apoptosis
morphogenetic apoptosis
GOC:dph
Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
dph
2009-05-18T02:12:13Z
biological_process
GO:0060623
regulation of chromosome condensation
Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
dph
2009-05-18T02:29:43Z
biological_process
GO:0060627
regulation of vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
dph
2009-05-18T03:07:02Z
biological_process
GO:0060632
regulation of microtubule-based movement
Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.
dph
2009-06-22T02:56:12Z
biological_process
GO:0060759
regulation of response to cytokine stimulus
Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.
GOC:BHF
GOC:dph
GOC:tb
Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.
dph
2009-06-22T02:58:04Z
biological_process
GO:0060760
positive regulation of response to cytokine stimulus
Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.
GOC:BHF
GOC:dph
GOC:tb
Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.
dph
2009-06-22T02:59:57Z
biological_process
GO:0060761
negative regulation of response to cytokine stimulus
Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.
GOC:BHF
GOC:dph
GOC:tb
Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
dph
2009-10-05T03:17:02Z
biological_process
GO:0060966
regulation of gene silencing by RNA
Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
dph
2009-10-05T03:21:05Z
biological_process
GO:0060967
negative regulation of gene silencing by RNA
Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
dph
2009-10-05T03:23:56Z
biological_process
GO:0060968
regulation of gene silencing
Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
dph
2009-10-05T03:26:19Z
biological_process
GO:0060969
negative regulation of gene silencing
Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
GOC:dph
GOC:tb
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
janelomax
2010-02-08T02:43:11Z
GO:0016044
GO:0044802
cellular membrane organisation
cellular membrane organization
membrane organisation
biological_process
membrane organization and biogenesis
single-organism membrane organization
GO:0061024
membrane organization
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GOC:dph
GOC:tb
membrane organisation
GOC:mah
membrane organization and biogenesis
GOC:mah
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
dph
2010-02-25T10:14:37Z
biological_process
GO:0061041
regulation of wound healing
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GOC:BHF
GOC:dph
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
dph
2010-02-25T10:18:26Z
biological_process
GO:0061042
vascular wound healing
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GOC:BHF
GOC:dph
Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
dph
2010-02-25T10:21:59Z
biological_process
GO:0061043
regulation of vascular wound healing
Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GOC:dph
Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
dph
2010-02-25T10:24:28Z
biological_process
GO:0061044
negative regulation of vascular wound healing
Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GOC:BHF
GOC:dph
Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
dph
2010-02-25T10:33:30Z
biological_process
GO:0061045
negative regulation of wound healing
Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GOC:dph
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.
dph
2012-11-07T09:07:00Z
biological_process
GO:0061476
response to anticoagulant
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.
GOC:dph
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.
dph
2012-11-07T09:08:36Z
biological_process
GO:0061477
response to aromatase inhibitor
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.
GOC:dph
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.
dph
2012-11-07T09:09:37Z
biological_process
GO:0061478
response to platelet aggregation inhibitor
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.
GOC:dph
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.
dph
2012-11-07T09:10:51Z
biological_process
GO:0061479
response to reverse transcriptase inhibitor
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.
GOC:dph
A process in which a protein is transported to, or maintained in, a location within a cilium.
dph
2013-03-22T15:41:44Z
biological_process
GO:0061512
protein localization to cilium
A process in which a protein is transported to, or maintained in, a location within a cilium.
GOC:dph
Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
dph
2014-05-15T09:12:24Z
RNA polymerase II sequence-specific DNA binding transcription factor binding
RNA polymerase II sequence-specific DNA-binding transcription factor binding
molecular_function
GO:0061629
RNA polymerase II-specific DNA-binding transcription factor binding
Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
GOC:dph
GOC:vw
Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.
dph
2014-11-06T13:15:27Z
small conjugating protein conjugating enzyme activity
molecular_function
E2
GO:0061650
ubiquitin-like protein conjugating enzyme activity
Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.
GOC:dph
small conjugating protein conjugating enzyme activity
GOC:dph
Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.
dph
2014-11-06T13:17:36Z
molecular_function
E2
GO:0061651
Atg12 conjugating enzyme activity
Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.
GOC:dph
E2
GOC:dph
Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
dph
2014-11-06T13:46:23Z
small conjugating protein ligase activity
molecular_function
E3
GO:0061659
ubiquitin-like protein ligase activity
Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
GOC:dph
small conjugating protein ligase activity
GOC:dph
E3
GOC:dph
Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.
dph
2014-11-06T13:50:42Z
molecular_function
E3
GO:0061660
Atg12 ligase activity
Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.
GOC:dph
E3
GOC:dph
The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.
dph
2015-09-14T14:10:24Z
biological_process
GO:0061736
engulfment of target by autophagosome
The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.
GOC:PARL
GOC:autophagy
GOC:dph
GOC:pad
Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.
dph
2015-11-09T12:40:29Z
biological_process
GO:0061743
motor learning
Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.
GOC:PARL
GOC:bf
Wikipedia:Motor_learning
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
dph
2016-11-06T23:08:01Z
mitotic spindle elongation during mitotic prophase
mitotic spindle elongation during prophase
mitotic spindle elongation during prophase and prometaphase
biological_process
GO:0061804
mitotic spindle formation (spindle phase one)
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
GOC:dph
GOC:vw
PMID:21920317
A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
dph
2017-07-13T19:42:14Z
biological_process
GO:0061919
process utilizing autophagic mechanism
A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
PMID:21997368
PMID:22966490
PMID:28596378
A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.
dph
2018-02-14T22:37:44Z
second meiotic division
biological_process
GO:0061983
meiosis II cell cycle process
A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.
PMID:29385397
second meiotic division
PMID:29385397
Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
dph
2018-03-19T14:11:54Z
regulation of small molecule metabolism
biological_process
GO:0062012
regulation of small molecule metabolic process
Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
GOC:vw
Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
dph
2018-03-19T14:25:10Z
positive regulation of small molecule metabolism
biological_process
GO:0062013
positive regulation of small molecule metabolic process
Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
GOC:vw
Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
dph
2018-03-19T14:27:23Z
negative regulation of small molecule metabolism
biological_process
GO:0062014
negative regulation of small molecule metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
GOC:vw
Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.
dph
2018-04-23T14:32:23Z
biological_process
GO:0062033
positive regulation of mitotic sister chromatid segregation
Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.
PMID:12773390
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).
dph
2019-05-30T16:45:04Z
biological_process
GO:0062125
regulation of mitochondrial gene expression
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).
PMID:28285835
The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.
dph
2019-09-13T13:48:47Z
biological_process
GO:0062149
detection of stimulus involved in sensory perception of pain
The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.
PMID:19837031
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
GO:0006461
biological_process
chaperone activity
macromolecular complex assembly
macromolecule complex assembly
protein complex assembly
protein complex formation
GO:0065003
protein-containing complex assembly
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
GOC:jl
Any process that modulates a measurable attribute of any biological process, quality or function.
regulation
biological_process
GO:0065007
biological regulation
Any process that modulates a measurable attribute of any biological process, quality or function.
GOC:dph
GOC:isa_complete
GOC:mah
GOC:pr
GOC:vw
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
regulation of biological attribute
regulation of biological characteristic
biological_process
GO:0065008
regulation of biological quality
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GOC:dph
GOC:isa_complete
GOC:mah
GOC:pr
GOC:vw
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
regulation of a molecular function
biological_process
GO:0065009
regulation of molecular function
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GOC:isa_complete
Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.
extracellular membrane-enclosed organelle
cellular_component
GO:0065010
extracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.
GOC:isa_complete
Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
Reactome:R-HSA-3065958
Reactome:R-HSA-3065959
Reactome:R-HSA-4167501
Reactome:R-HSA-6803060
molecular_function
GO:0070011
peptidase activity, acting on L-amino acid peptides
Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GOC:mah
Reactome:R-HSA-3065958
An unknown protease degrades ACACA
Reactome:R-HSA-3065959
An unknown protease degrades hCBXs
Reactome:R-HSA-4167501
An unknown protease degrades ACACB
Reactome:R-HSA-6803060
DCD(63-110) is processed to DCD(63-109)
An organelle lumen that is part of an intracellular organelle.
cellular_component
GO:0070013
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
GOC:mah
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
exosome
extracellular vesicular exosome
cellular_component
GO:0070062
extracellular exosome
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
GOC:BHF
GOC:mah
GOC:vesicles
PMID:15908444
PMID:17641064
PMID:19442504
PMID:19498381
PMID:22418571
PMID:24009894
exosome
GOC:pr
extracellular vesicular exosome
GOC:vesicles
The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
Wikipedia:Glycosylation
biological_process
GO:0070085
glycosylation
The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
GOC:hjd
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
response to UV-A light stimulus
response to UV-A radiation stimulus
response to UVA light stimulus
response to UVA radiation stimulus
biological_process
GO:0070141
response to UV-A
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
GOC:BHF
GOC:mah
A process of chromosome organization that is involved in a meiotic cell cycle.
chromosome organisation involved in meiosis
meiotic chromosome organization
biological_process
GO:0070192
chromosome organization involved in meiotic cell cycle
A process of chromosome organization that is involved in a meiotic cell cycle.
GOC:mah
chromosome organisation involved in meiosis
GOC:mah
meiotic chromosome organization
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
regulation of establishment of protein localisation
biological_process
GO:0070201
regulation of establishment of protein localization
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
GOC:BHF
GOC:mah
regulation of establishment of protein localisation
GOC:mah
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
regulation of microtubule cytoskeleton organisation
regulation of microtubule dynamics
biological_process
GO:0070507
regulation of microtubule cytoskeleton organization
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GOC:mah
regulation of microtubule cytoskeleton organisation
GOC:mah
regulation of microtubule dynamics
GOC:dph
GOC:tb
The adhesion of one platelet to one or more other platelets via adhesion molecules.
blood platelet aggregation
biological_process
thrombocyte aggregation
GO:0070527
platelet aggregation
The adhesion of one platelet to one or more other platelets via adhesion molecules.
GOC:BHF
GOC:vk
blood platelet aggregation
CL:0000233
thrombocyte aggregation
CL:0000233
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
midori
2009-06-16T04:08:29Z
cellular macromolecule localisation
biological_process
GO:0070727
cellular macromolecule localization
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:mah
cellular macromolecule localisation
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
midori
2009-08-27T04:41:45Z
biological_process
GO:0070887
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to chemical stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
midori
2009-09-15T03:00:51Z
biological_process
GO:0070925
organelle assembly
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:mah
A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.
midori
2009-11-09T11:36:34Z
DNA conformation modification
biological_process
GO:0071103
DNA conformation change
A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.
GOC:mah
DNA conformation modification
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
midori
2009-12-03T01:02:11Z
cellular response to abiotic stress
biological_process
GO:0071214
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to abiotic stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
GOC:mah
cellular response to abiotic stress
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
midori
2009-12-10T04:46:04Z
biological_process
GO:0071310
cellular response to organic substance
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
midori
2009-12-11T03:49:02Z
biological_process
GO:0071383
cellular response to steroid hormone stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
midori
2009-12-11T04:37:10Z
biological_process
GO:0071396
cellular response to lipid
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
midori
2009-12-14T02:55:58Z
cellular response to organic cyclic substance
biological_process
GO:0071407
cellular response to organic cyclic compound
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
GOC:mah
cellular response to organic cyclic substance
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
midori
2009-12-18T11:41:54Z
biological_process
GO:0071467
cellular response to pH
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GOC:mah
Wikipedia:PH
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
midori
2009-12-18T01:59:37Z
cellular response to electromagnetic radiation stimulus
cellular response to radiation stimulus
biological_process
GO:0071478
Note that 'radiation' refers to electromagnetic radiation of any wavelength.
cellular response to radiation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
GOC:mah
cellular response to electromagnetic radiation stimulus
GOC:mah
cellular response to radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
midori
2009-12-18T02:00:31Z
cellular response to ionising radiation
cellular response to ionizing radiation stimulus
biological_process
GO:0071479
cellular response to ionizing radiation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
GOC:mah
cellular response to ionising radiation
GOC:mah
cellular response to ionizing radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
midori
2009-12-18T02:00:50Z
biological_process
cellular response to gamma ray
cellular response to gamma-ray photon
GO:0071480
cellular response to gamma radiation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
GOC:mah
cellular response to gamma ray
GOC:mah
cellular response to gamma-ray photon
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
midori
2009-12-18T02:00:59Z
cellular response to X-ray radiation stimulus
biological_process
GO:0071481
cellular response to X-ray
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
GOC:mah
cellular response to X-ray radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
midori
2009-12-18T02:03:49Z
biological_process
GO:0071482
cellular response to light stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
midori
2009-12-18T02:09:48Z
cellular response to blue light stimulus
biological_process
GO:0071483
cellular response to blue light
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
GOC:mah
cellular response to blue light stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
midori
2009-12-18T02:11:03Z
biological_process
GO:0071484
cellular response to light intensity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
midori
2009-12-18T02:13:12Z
biological_process
cellular response to darkness
GO:0071485
cellular response to absence of light
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
midori
2009-12-18T02:13:23Z
biological_process
GO:0071486
cellular response to high light intensity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
midori
2009-12-18T02:13:29Z
biological_process
GO:0071487
cellular response to low light intensity stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
midori
2009-12-18T02:13:40Z
biological_process
GO:0071488
cellular response to very low light intensity stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
midori
2009-12-18T02:18:25Z
biological_process
GO:0071489
cellular response to red or far red light
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
midori
2009-12-18T02:19:40Z
cellular response to far red light stimulus
biological_process
GO:0071490
cellular response to far red light
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mah
cellular response to far red light stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
midori
2009-12-18T02:19:47Z
cellular response to red light stimulus
biological_process
GO:0071491
cellular response to red light
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GOC:mah
cellular response to red light stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
midori
2009-12-18T02:21:51Z
cellular response to UV-A light stimulus
cellular response to UV-A radiation stimulus
cellular response to UVA light stimulus
cellular response to UVA radiation stimulus
biological_process
GO:0071492
cellular response to UV-A
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
GOC:mah
cellular response to UV-A light stimulus
GOC:mah
cellular response to UV-A radiation stimulus
GOC:mah
cellular response to UVA light stimulus
GOC:mah
cellular response to UVA radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
midori
2009-12-18T02:21:56Z
cellular response to UV-B light stimulus
cellular response to UV-B radiation stimulus
cellular response to UVB light stimulus
cellular response to UVB radiation stimulus
cellular response to medium wave ultraviolet light stimulus
cellular response to medium wave ultraviolet radiation stimulus
biological_process
GO:0071493
cellular response to UV-B
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
GOC:mah
cellular response to UV-B light stimulus
GOC:mah
cellular response to UV-B radiation stimulus
GOC:mah
cellular response to UVB light stimulus
GOC:mah
cellular response to UVB radiation stimulus
GOC:mah
cellular response to medium wave ultraviolet light stimulus
GOC:mah
cellular response to medium wave ultraviolet radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
midori
2009-12-18T02:22:01Z
cellular response to UV-C light stimulus
cellular response to UV-C radiation stimulus
cellular response to UVC light stimulus
cellular response to UVC radiation stimulus
cellular response to germicidal ultraviolet light stimulus
cellular response to germicidal ultraviolet radiation stimulus
cellular response to shortwave ultraviolet light stimulus
cellular response to shortwave ultraviolet radiation stimulus
biological_process
GO:0071494
cellular response to UV-C
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
GOC:mah
cellular response to UV-C light stimulus
GOC:mah
cellular response to UV-C radiation stimulus
GOC:mah
cellular response to UVC light stimulus
GOC:mah
cellular response to UVC radiation stimulus
GOC:mah
cellular response to germicidal ultraviolet light stimulus
GOC:mah
cellular response to germicidal ultraviolet radiation stimulus
GOC:mah
cellular response to shortwave ultraviolet light stimulus
GOC:mah
cellular response to shortwave ultraviolet radiation stimulus
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
midori
2009-12-18T02:25:40Z
biological_process
GO:0071495
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to endogenous stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
midori
2009-12-18T02:36:52Z
biological_process
GO:0071496
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to external stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GOC:mah
Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
midori
2010-02-25T04:00:13Z
protein localisation in extracellular region
protein localization in extracellular region
biological_process
GO:0071692
protein localization to extracellular region
Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
GOC:mah
protein localisation in extracellular region
GOC:mah
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.
midori
2010-03-02T11:43:38Z
biological_process
GO:0071695
anatomical structure maturation
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.
GOC:mah
The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
midori
2010-03-08T02:15:14Z
biological_process
GO:0071702
organic substance transport
The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GOC:mah
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
midori
2010-03-08T03:32:18Z
organic molecular entity metabolic process
organic molecular entity metabolism
organic substance metabolism
biological_process
GO:0071704
organic substance metabolic process
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GOC:mah
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
midori
2010-03-08T03:56:28Z
biological_process
GO:0071705
nitrogen compound transport
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
midori
2010-09-10T01:39:16Z
GO:0071841
cellular component organisation or biogenesis
cellular component organisation or biogenesis at cellular level
cellular component organization or biogenesis at cellular level
biological_process
GO:0071840
cellular component organization or biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GOC:mah
cellular component organisation or biogenesis
GOC:mah
cellular component organisation or biogenesis at cellular level
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
midori
2010-09-13T02:36:37Z
response to monoamine stimulus
biological_process
GO:0071867
response to monoamine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
GOC:mah
response to monoamine stimulus
GOC:dos
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
midori
2010-10-04T01:51:47Z
cellular_component
GO:0071944
cell periphery
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.
midori
2010-10-18T03:44:18Z
extracellular vesicular exosome assembly
biological_process
GO:0071971
extracellular exosome assembly
The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.
GOC:mah
GOC:tfm
PMID:19442504
PMID:27462458
extracellular vesicular exosome assembly
GOC:vesicles
The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
midori
2010-11-04T12:18:23Z
amino acid derivative transport
biological_process
GO:0072337
modified amino acid transport
The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
midori
2010-11-10T01:26:18Z
response to anaesthetic
biological_process
GO:0072347
response to anesthetic
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
GOC:sart
response to anaesthetic
GOC:mah
Enables the transfer of modified amino acids from one side of a membrane to the other.
midori
2010-11-11T11:50:31Z
modified amino acid transporter activity
amino acid derivative transmembrane transporter activity
molecular_function
GO:0072349
modified amino acid transmembrane transporter activity
Enables the transfer of modified amino acids from one side of a membrane to the other.
GOC:mah
modified amino acid transporter activity
GOC:mah
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
midori
2010-11-16T11:25:49Z
biological_process
GO:0072358
cardiovascular system development
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
GOC:mah
UBERON:0004535
The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
midori
2010-11-16T11:27:39Z
biological_process
GO:0072359
circulatory system development
The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
GOC:mah
UBERON:0001009
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
midori
2010-11-22T11:26:54Z
middle-term memory
MTM
biological_process
GO:0072375
medium-term memory
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
GOC:sart
PMID:14659098
PMID:7923375
middle-term memory
GOC:sart
MTM
GOC:sart
Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.
midori
2010-12-16T01:25:40Z
biological_process
GO:0072503
Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular trivalent inorganic cation homeostasis' ; GO:0072504').
cellular divalent inorganic cation homeostasis
Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.
GOC:mah
Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.
midori
2010-12-16T01:39:00Z
biological_process
GO:0072505
Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'trivalent inorganic anion homeostasis' ; GO:0072506').
divalent inorganic anion homeostasis
Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.
GOC:mah
Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.
midori
2010-12-16T01:39:39Z
biological_process
GO:0072506
Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'divalent inorganic anion homeostasis' ; GO:0072505').
trivalent inorganic anion homeostasis
Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.
GOC:mah
Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.
midori
2010-12-16T03:22:48Z
biological_process
GO:0072507
Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'trivalent inorganic cation homeostasis' ; GO:0072508').
divalent inorganic cation homeostasis
Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.
GOC:mah
The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
midori
2011-01-04T03:03:59Z
purine and derivative metabolic process
purine-containing compound metabolism
biological_process
GO:0072521
purine-containing compound metabolic process
The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
GOC:mah
purine-containing compound metabolism
GOC:mah
The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
midori
2011-01-04T03:15:29Z
purine and derivative biosynthetic process
purine-containing compound anabolism
purine-containing compound biosynthesis
purine-containing compound formation
purine-containing compound synthesis
biological_process
GO:0072522
purine-containing compound biosynthetic process
The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
GOC:mah
purine-containing compound anabolism
GOC:mah
purine-containing compound biosynthesis
GOC:mah
purine-containing compound formation
GOC:mah
purine-containing compound synthesis
GOC:mah
The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
midori
2011-01-04T03:27:19Z
pyrimidine and derivative metabolic process
pyrimidine-containing compound metabolism
biological_process
GO:0072527
pyrimidine-containing compound metabolic process
The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
GOC:mah
pyrimidine-containing compound metabolism
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
midori
2012-04-30T11:31:05Z
biological_process
GO:0072718
response to cisplatin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
midori
2012-11-09T11:34:51Z
biological_process
GO:0072758
response to topoisomerase inhibitor
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
GOC:mah
Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
autophagy of host cells during interaction with symbiont
autophagy of host cells involved in interaction with symbiont
positive regulation by symbiont of host autophagotic process
GO:0075044
positive regulation by symbiont of host autophagy
Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
autophagy of host cells during interaction with symbiont
GOC:dph
Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
biological_process
autophagy during symbiotic interaction
autophagy involved in symbiotic interaction
modulation by symbiont of host autophagic process
GO:0075071
modulation by symbiont of host autophagy
Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pamgo_curators
autophagy during symbiotic interaction
GOC:dph
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
donghui
2009-04-22T04:30:52Z
biological_process
GO:0080090
regulation of primary metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
PMID:19211694
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
donghui
2009-05-06T04:51:28Z
biological_process
GO:0080134
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:dhl
Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
donghui
2009-05-06T05:02:52Z
biological_process
GO:0080135
regulation of cellular response to stress
Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:dhl
Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
donghui
2010-09-01T03:44:27Z
biological_process
GO:0080154
regulation of fertilization
Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GOC:DHL
PMID:20478994
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
tanyaberardini
2009-09-09T11:39:52Z
biological_process
GO:0090068
positive regulation of cell cycle process
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tanyaberardini
2009-10-23T11:21:38Z
biological_process
GO:0090087
regulation of peptide transport
Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:dph
GOC:tb
Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure.
tanyaberardini
2009-12-08T02:12:19Z
biological_process
GO:0090139
mitochondrial DNA packaging
Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure.
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
tanyaberardini
2009-12-11T10:17:51Z
regulation of spindle formation
biological_process
GO:0090169
regulation of spindle assembly
Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of spindle formation
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.
tanyaberardini
2010-01-13T11:04:53Z
regulation of spindle organisation
biological_process
GO:0090224
regulation of spindle organization
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of spindle organisation
GOC:mah
Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
tanyaberardini
2010-01-19T04:03:29Z
regulation of phytochrome signaling pathway
regulation of red or far-red light signalling pathway
biological_process
GO:0090227
regulation of red or far-red light signaling pathway
Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GOC:tb
regulation of phytochrome signaling pathway
GOC:tb
regulation of red or far-red light signalling pathway
GOC:mah
Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
tanyaberardini
2010-01-19T04:03:29Z
positive regulation of phytochrome signaling pathway
positive regulation of red or far-red light signalling pathway
biological_process
GO:0090228
positive regulation of red or far-red light signaling pathway
Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GOC:tb
positive regulation of phytochrome signaling pathway
GOC:tb
positive regulation of red or far-red light signalling pathway
GOC:mah
Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
tanyaberardini
2010-01-19T04:03:29Z
negative regulation of phytochrome signaling pathway
negative regulation of red or far-red light signalling pathway
biological_process
GO:0090229
negative regulation of red or far-red light signaling pathway
Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GOC:tb
negative regulation of phytochrome signaling pathway
GOC:tb
negative regulation of red or far-red light signalling pathway
GOC:mah
Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
tanyaberardini
2010-02-18T02:43:55Z
regulation of protein amino acid glycosylation in Golgi
biological_process
GO:0090283
regulation of protein glycosylation in Golgi
Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
GOC:pr
GOC:tb
regulation of protein amino acid glycosylation in Golgi
GOC:bf
Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
tanyaberardini
2010-02-18T02:43:55Z
positive regulation of protein amino acid glycosylation in Golgi
biological_process
GO:0090284
positive regulation of protein glycosylation in Golgi
Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
GOC:pr
GOC:tb
positive regulation of protein amino acid glycosylation in Golgi
GOC:bf
Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
tanyaberardini
2010-02-18T02:43:55Z
negative regulation of protein amino acid glycosylation in Golgi
biological_process
GO:0090285
negative regulation of protein glycosylation in Golgi
Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
GOC:pr
GOC:tb
negative regulation of protein amino acid glycosylation in Golgi
GOC:bf
Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
tanyaberardini
2010-03-22T02:12:03Z
biological_process
GO:0090303
positive regulation of wound healing
Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GOC:BHF
Any cellular metabolic process involving nucleic acids.
tanyaberardini
2010-04-07T10:18:47Z
biological_process
GO:0090304
nucleic acid metabolic process
Any cellular metabolic process involving nucleic acids.
GOC:dph
GOC:tb
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
tanyaberardini
2010-04-09T11:21:56Z
meiotic spindle assembly
biological_process
GO:0090306
spindle assembly involved in meiosis
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
GOC:tb
GOC:vw
meiotic spindle assembly
GOC:vw
Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.
tanyaberardini
2010-04-09T11:31:28Z
spindle assembly involved in mitosis
biological_process
GO:0090307
mitotic spindle assembly
Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.
GOC:tb
GOC:vw
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
tanyaberardini
2010-04-16T03:45:07Z
biological_process
GO:0090316
positive regulation of intracellular protein transport
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
GOC:tb
Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
tanyaberardini
2010-04-16T03:45:07Z
biological_process
GO:0090317
negative regulation of intracellular protein transport
Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
GOC:tb
Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
tanyaberardini
2010-05-14T10:24:29Z
biological_process
GO:0090325
regulation of locomotion involved in locomotory behavior
Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GOC:dph
GOC:kmv
GOC:tb
Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
tanyaberardini
2010-05-14T10:26:58Z
biological_process
GO:0090326
positive regulation of locomotion involved in locomotory behavior
Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GOC:dph
GOC:kmv
GOC:tb
Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
tanyaberardini
2010-05-14T10:26:58Z
biological_process
GO:0090327
negative regulation of locomotion involved in locomotory behavior
Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GOC:dph
GOC:kmv
GOC:tb
Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
tanyaberardini
2010-05-14T10:37:22Z
biological_process
GO:0090328
regulation of olfactory learning
Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
tanyaberardini
2010-05-14T10:46:08Z
biological_process
GO:0090330
regulation of platelet aggregation
Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
tanyaberardini
2010-05-14T10:46:08Z
platelet disaggregation
biological_process
GO:0090331
negative regulation of platelet aggregation
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GOC:BHF
platelet disaggregation
GOC:dph
PMID:12871378
The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
tanyaberardini
2011-02-26T02:22:41Z
biological_process
GO:0090407
organophosphate biosynthetic process
The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
GOC:chem_mtg
Enables the transfer of a vitamin from one side of a membrane to the other.
tanyaberardini
2012-10-02T16:50:50Z
GO:0051183
vitamin or cofactor transporter activity
molecular_function
vitamin transporter activity
GO:0090482
vitamin transmembrane transporter activity
Enables the transfer of a vitamin from one side of a membrane to the other.
GOC:tb
The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.
tanyaberardini
2014-08-12T12:13:53Z
biological_process
GO:0090594
inflammatory response to wounding
The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.
GOC:add
A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
tanyaberardini
2014-09-16T14:44:46Z
biological_process
solid substrate biofilm formation
GO:0090605
submerged biofilm formation
A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GOC:di
GOC:tb
A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
tanyaberardini
2014-09-16T14:55:15Z
biological_process
GO:0090609
single-species submerged biofilm formation
A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GOC:di
GOC:tb
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
paola
2011-03-23T01:52:31Z
cilium plasm
microtubule-based flagellar matrix
microtubule-based flagellum matrix
cellular_component
cilial cytoplasm
ciliary cytoplasm
cilium cytoplasm
microtubule-based flagellar cytoplasm
microtubule-based flagellum cytoplasm
GO:0097014
Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm".
ciliary plasm
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
GOC:BHF
GOC:cilia
GOC:dos
PMID:17895364
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
paola
2011-06-07T11:22:09Z
cellular_component
GO:0097060
synaptic membrane
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GOC:BHF
PMID:20410104
Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
paola
2011-09-23T02:31:01Z
molecular_function
GO:0097159
organic cyclic compound binding
Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
GOC:sjw
PMID:7583672
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
paola
2011-11-23T09:30:23Z
GO:0008624
apoptotic signalling pathway
induction of apoptosis by extracellular signals
biological_process
GO:0097190
This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
apoptotic signaling pathway
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
GOC:mtg_apoptosis
apoptotic signalling pathway
GOC:mah
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
paola
2011-11-23T09:45:24Z
execution phase of apoptotic process
apoptosis
biological_process
GO:0097194
execution phase of apoptosis
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GOC:mtg_apoptosis
PMID:21760595
The temporary recovery of response to a stimulus when a novel stimulus is added.
paola
2012-03-20T01:39:25Z
biological_process
GO:0097270
dishabituation
The temporary recovery of response to a stimulus when a novel stimulus is added.
GOC:kmv
PMID:11390637
Wikipedia:Habituation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
paola
2012-05-15T03:48:45Z
GO:1990335
process resulting in tolerance to alcohol
biological_process
GO:0097305
response to alcohol
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
GOC:pr
PMID:24014527
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
paola
2012-06-12T10:48:28Z
biological_process
GO:0097327
response to antineoplastic agent
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.
paola
2012-06-12T10:50:34Z
biological_process
GO:0097328
response to carboplatin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
paola
2012-06-12T10:52:01Z
biological_process
GO:0097329
response to antimetabolite
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
paola
2012-06-12T10:53:35Z
biological_process
GO:0097330
response to 5-fluoro-2'-deoxyuridine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.
paola
2012-06-12T10:55:29Z
biological_process
GO:0097331
response to cytarabine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
paola
2012-06-12T10:58:13Z
biological_process
GO:0097332
response to antipsychotic drug
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.
paola
2012-06-12T11:00:04Z
biological_process
GO:0097333
response to olanzapine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
paola
2012-06-12T11:01:14Z
biological_process
GO:0097334
response to perphenazine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.
paola
2012-06-12T11:03:22Z
biological_process
GO:0097335
response to quetiapine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.
paola
2012-06-12T11:04:31Z
biological_process
GO:0097336
response to risperidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
paola
2012-06-12T11:05:31Z
biological_process
GO:0097337
response to ziprasidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
paola
2012-06-12T11:07:01Z
biological_process
GO:0097338
response to clozapine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
paola
2012-08-01T16:13:31Z
response to bronchodilator agent
biological_process
response to broncholytic agent
GO:0097366
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to bronchodilator
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
GOC:hp
OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER).
GO:0005790
paola
2012-11-07T13:45:14Z
NIF_Subcellular:sao184202831
cellular_component
SER subcomponent
GO:0097425
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete smooth endoplasmic reticulum part
true
OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER).
NIF_Subcellular:sao184202831
SER subcomponent
NIF_Subcellular:sao1842028314
OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
CL:0000540
paola
2012-12-19T16:53:50Z
cellular_component
GO:0097458
obsolete neuron part
true
OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
GOC:pr
Wikipedia:Neuron
The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).
paola
2014-10-01T13:49:27Z
biological_process
GO:0097659
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
nucleic acid-templated transcription
The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).
GOC:pr
GOC:txnOH
GOC:vw
Any vesicle that is part of the intracellular region.
paola
2016-03-29T17:39:45Z
cellular_component
GO:0097708
intracellular vesicle
Any vesicle that is part of the intracellular region.
GOC:vesicles
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
paola
2016-08-05T16:12:33Z
Reactome:R-HSA-5620912.1
ciliary basal body docking
biological_process
anchoring of the basal body to the plasma membrane
GO:0097711
Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.
ciliary basal body-plasma membrane docking
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
GOC:cilia
PMID:13978319
PMID:23348840
PMID:23530209
PMID:25686250
PMID:26981235
Reactome:R-HSA-5620912.1
The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
paola
2016-08-05T16:16:28Z
biological_process
GO:0097712
vesicle targeting, trans-Golgi to periciliary membrane compartment
The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
GOC:cilia
PMID:20106869
PMID:23351793
PMID:24814148
PMID:26485645
Reactome:R-HSA-5620920.1
Any process involved in the controlled movement of a sperm cell.
paola
2016-09-01T12:00:45Z
sperm movement
biological_process
GO:0097722
sperm motility
Any process involved in the controlled movement of a sperm cell.
GOC:cilia
GOC:krc
The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
paola
2016-10-03T14:35:25Z
exosome assembly or secretion
exosome biogenesis
exosome production
biological_process
ILV assembly
intraluminal vesicle assembly
GO:0097734
extracellular exosome biogenesis
The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
GOC:PARL
GOC:bf
PMID:19442504
PMID:25392495
The lipid bilayer that forms the outer-most layer of an organelle.
davidos
2014-02-26T13:41:31Z
cellular_component
GO:0098588
Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.
bounding membrane of organelle
The lipid bilayer that forms the outer-most layer of an organelle.
GOC:dos
A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane.
2014-03-06T11:37:54Z
region of membrane
cellular_component
GO:0098589
Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
membrane region
A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane.
GOC:dos
A membrane that is a (regional) part of the plasma membrane.
davidos
2014-03-06T11:55:32Z
region of plasma membrane
cellular_component
GO:0098590
Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
plasma membrane region
A membrane that is a (regional) part of the plasma membrane.
GOC:dos
The attachment of one cell to another cell via adhesion molecules.
davidos
2014-04-16T13:40:03Z
GO:0016337
biological_process
single organismal cell-cell adhesion
GO:0098609
cell-cell adhesion
The attachment of one cell to another cell via adhesion molecules.
GOC:dos
The clustering together of unicellular organisms in suspension form aggregates.
aggregation of single cell organisms
biological_process
GO:0098630
aggregation of unicellular organisms
The clustering together of unicellular organisms in suspension form aggregates.
GOC:dos
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
cell adhesion molecule
protein binding involved in cell adhesion
molecular_function
GO:0098631
cell adhesion mediator activity
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
Wikipedia:Cell_adhesion
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
cell-cell adhesion molecule
protein binding involved in cell-cell adhesion
molecular_function
GO:0098632
cell-cell adhesion mediator activity
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
Wikipedia:Cell_adhesion
The process in which an anion is transported across a membrane.
GO:0099133
ATP hydrolysis coupled anion transmembrane transport
biological_process
GO:0098656
anion transmembrane transport
The process in which an anion is transported across a membrane.
GOC:dos
GOC:vw
The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
biological_process
GO:0098743
cell aggregation
The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
GOC:dos
One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
biological_process
GO:0098762
This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic cell cycle phase
One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GOC:dos
One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
biological_process
GO:0098763
This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic cell cycle phase
One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GOC:dos
A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.
biological_process
GO:0098764
This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiosis I cell cycle phase
A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.
GOC:dos
A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).
biological_process
GO:0098765
This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiosis II cell cycle phase
A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).
GOC:dos
Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
biological_process
GO:0098771
inorganic ion homeostasis
Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
GOC:dos
A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
molecular_function
GO:0098772
molecular function regulator
A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
GOC:dos
GOC:pt
A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi Apparatus.
cellular_component
GO:0098791
Golgi subcompartment
A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi Apparatus.
GOC:dos
The part of a synapse that is part of the post-synaptic cell.
cellular_component
GO:0098794
postsynapse
The part of a synapse that is part of the post-synaptic cell.
GOC:dos
Any protein complex that is part of a membrane.
cellular_component
GO:0098796
membrane protein complex
Any protein complex that is part of a membrane.
GOC:dos
Any protein complex that is part of the plasma membrane.
cellular_component
GO:0098797
plasma membrane protein complex
Any protein complex that is part of the plasma membrane.
GOC:dos
A protein complex that is part of a mitochondrion.
cellular_component
GO:0098798
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
mitochondrial protein complex
A protein complex that is part of a mitochondrion.
GOC:dos
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.
biological_process
GO:0098801
regulation of renal system process
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.
GOC:dos
Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.
cellular_component
GO:0098805
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
whole membrane
Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.
GOC:dos
The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
biological_process
GO:0098813
nuclear chromosome segregation
The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
GOC:dos
A distinct region of the endoplasmic reticulum
cellular_component
GO:0098827
endoplasmic reticulum subcompartment
A distinct region of the endoplasmic reticulum
GOC:dos
The directed movement of a protein along a microtubule, mediated by motor proteins.
microtubule-based protein transport
biological_process
GO:0098840
protein transport along microtubule
The directed movement of a protein along a microtubule, mediated by motor proteins.
PMID:25987607
A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.
cellular_component
GO:0098857
membrane microdomain
A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.
PMID:20044567
PMID:26253820
A synapse in which pre and post-synaptic cells are neurons.
cellular_component
GO:0098984
neuron to neuron synapse
A synapse in which pre and post-synaptic cells are neurons.
GOC:dos
Any vesicle-mediated transport that occurs in a synapse
biological_process
GO:0099003
vesicle-mediated transport in synapse
Any vesicle-mediated transport that occurs in a synapse
GOC:dos
A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
cellular_component
GO:0099091
postsynaptic specialization, intracellular component
A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GOC:dos
A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
cellular_component
GO:0099092
postsynaptic density, intracellular component
A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GOC:dos
A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
biological_process
GO:0099111
microtubule-based transport
A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GOC:cjm
ISBN:0815316194
A microtubule-based process that results in the transport of proteins.
biological_process
GO:0099118
microtubule-based protein transport
A microtubule-based process that results in the transport of proteins.
GOC:vw
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
cellular_component
GO:0099503
secretory vesicle
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
GOC:dos
Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol
cellular_component
GO:0099522
region of cytosol
Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol
GOC:dos
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
cellular_component
GO:0099524
postsynaptic cytosol
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
GOC:dos
Cell-cell signaling to, from or within a synapse.
biological_process
GO:0099536
synaptic signaling
Cell-cell signaling to, from or within a synapse.
GOC:dos
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm"
cellular_component
GO:0099568
cytoplasmic region
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm"
GOC:dos
The portion of the cytoskeleton contained within the postsynapse.
cellular_component
GO:0099571
postsynaptic cytoskeleton
The portion of the cytoskeleton contained within the postsynapse.
GOC:dos
PMID:19889835
A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
cellular_component
GO:0099572
postsynaptic specialization
A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
PMID:22046028
Any signal release from a synapse.
biological_process
GO:0099643
signal release from synapse
Any signal release from a synapse.
GOC:dos
The complete extent of cell cortex that underlies some some region of the plasma membrane
perimembrane region
cellular_component
GO:0099738
cell cortex region
The complete extent of cell cortex that underlies some some region of the plasma membrane
GOC:dos
OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively_regulates single organismal cell-cell adhesion
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100017
This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively_regulates single organismal cell-cell adhesion
GOC:cjm
GOC:obol
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100020
This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of transport by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport
GOC:cjm
GOC:obol
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100023
This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division
GOC:cjm
GOC:obol
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100024
This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process
GOC:cjm
GOC:obol
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates purine nucleotide biosynthetic process
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100036
This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates purine nucleotide biosynthetic process
GOC:cjm
GOC:obol
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates meiotic nuclear division
cjm
2015-04-02T04:13:19Z
biological_process
GO:0100051
This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter
true
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates meiotic nuclear division
GOC:cjm
GOC:obol
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.
dos
2017-02-17T16:02:42Z
biological_process
GO:0104004
cellular response to environmental stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.
GOC:dos
Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.
hjd
2017-04-28T20:03:14Z
biological_process
GO:0106014
regulation of inflammatory response to wounding
Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:26022821
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
hjd
2017-04-28T20:09:46Z
biological_process
GO:0106015
negative regulation of inflammatory response to wounding
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:26022821
Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
hjd
2017-04-28T20:16:31Z
biological_process
GO:0106016
positive regulation of inflammatory response to wounding
Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:26022821
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
hjd
2017-10-27T17:33:05Z
biological_process
GO:0106064
regulation of cobalamin metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
PMID:29056341
Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.
hjd
2018-05-01T18:07:12Z
biological_process
GO:0106121
positive regulation of cobalamin metabolic process
Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.
PMID:29056341
Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.
hjd
2018-05-01T18:12:48Z
biological_process
GO:0106122
negative regulation of cobalamin metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.
PMID:29056341
Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
kmv
2017-07-06T14:14:08Z
biological_process
GO:0110028
positive regulation of mitotic spindle organization
Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
GOC:bhm
PMID:17576815
Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.
kmv
2018-07-05T14:10:14Z
biological_process
GO:0110110
positive regulation of animal organ morphogenesis
Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.
GOC:kmv
Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.
kmv
2018-07-05T14:25:21Z
biological_process
GO:0110111
negative regulation of animal organ morphogenesis
Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.
GOC:kmv
Any process that modulates the frequency, rate or extent of mitotic spindle formation (spindle phase one).
kmv
2019-08-12T15:10:26Z
biological_process
GO:0110159
regulation of mitotic spindle formation (spindle phase one)
Any process that modulates the frequency, rate or extent of mitotic spindle formation (spindle phase one).
GOC:vw
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle formation (spindle phase one).
kmv
2019-08-12T15:18:32Z
biological_process
GO:0110160
negative regulation of mitotic spindle formation (spindle phase one)
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle formation (spindle phase one).
GOC:vw
Any process that activates or increases the frequency, rate or extent of mitotic spindle formation (spindle phase one).
kmv
2019-08-12T15:21:08Z
biological_process
GO:0110161
positive regulation of mitotic spindle formation (spindle phase one)
Any process that activates or increases the frequency, rate or extent of mitotic spindle formation (spindle phase one).
GOC:vw
A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.
kmv
2019-08-12T18:01:37Z
cellular_component
GO:0110165
cellular anatomical entity
A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.
GOC:kmv
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
kchris
2017-03-21T17:26:07Z
cellular_component
GO:0120025
plasma membrane bounded cell projection
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GOC:krc
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
kchris
2017-04-24T23:56:08Z
eupodium
biological_process
GO:0120031
plasma membrane bounded cell projection assembly
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GOC:krc
eupodium
GOC:krc
GOC:rjd
PMID:10328951
PMID:9096956
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:27:04Z
biological_process
GO:0120032
regulation of plasma membrane bounded cell projection assembly
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:34:31Z
biological_process
GO:0120033
negative regulation of plasma membrane bounded cell projection assembly
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:34:45Z
biological_process
GO:0120034
positive regulation of plasma membrane bounded cell projection assembly
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
kchris
2017-04-26T16:02:06Z
biological_process
GO:0120035
regulation of plasma membrane bounded cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
GOC:krc
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
kchris
2017-04-26T16:07:02Z
biological_process
GO:0120036
plasma membrane bounded cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
GOC:krc
OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.
GO:0120025
kchris
2017-04-28T17:20:43Z
cellular_component
GO:0120038
obsolete plasma membrane bounded cell projection part
true
OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.
GOC:krc
All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.
kchris
2017-11-01T18:58:12Z
cellular_component
GO:0120111
neuron projection cytoplasm
All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.
GOC:ha
One of the two nuclear divisions that occur as part of the meiotic cell cycle.
pg
2017-03-23T09:40:00Z
biological_process
GO:0140013
meiotic nuclear division
One of the two nuclear divisions that occur as part of the meiotic cell cycle.
PMID:9334324
A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
pg
2017-03-23T14:44:23Z
biological_process
GO:0140014
mitotic nuclear division
A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
ISBN:0198547684
The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.
pg
2017-05-24T11:37:30Z
biological_process
GO:0140039
cell-cell adhesion in response to extracellular stimulus
The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.
PMID:14996911
The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
pg
2017-06-26T10:57:45Z
biological_process
GO:0140053
mitochondrial gene expression
The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
PMID:27058308
The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.
pg
2017-06-27T09:58:51Z
biological_process
GO:0140056
organelle localization by membrane tethering
The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.
PMID:27875684
Catalytic activity that acts to modify a protein.
https://github.com/geneontology/go-ontology/issues/14225
pg
2017-09-14T10:32:59Z
molecular_function
GO:0140096
catalytic activity, acting on a protein
Catalytic activity that acts to modify a protein.
GOC:molecular_function_refactoring
GOC:pdt
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
https://github.com/geneontology/go-ontology/issues/14256
pg
2017-10-23T11:53:42Z
extracellular vesicle assembly
biological_process
GO:0140112
extracellular vesicle biogenesis
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
PMID:28736435
Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
pg
2018-11-28T12:48:20Z
molecular_function
GO:0140297
DNA-binding transcription factor binding
Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
GOC:txnOH-2018
Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
pg
2019-04-03T09:21:48Z
biological_process
GO:0140321
negative regulation by symbiont of host autophagy
Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GOC:pg
The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
pg
2019-05-22T11:20:45Z
efflux
biological_process
GO:0140352
export from cell
The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
GOC:pg
Any process that modulates the frequency, rate or extent of hemostasis.
jl
2012-01-19T03:23:38Z
biological_process
GO:1900046
regulation of hemostasis
Any process that modulates the frequency, rate or extent of hemostasis.
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.
jl
2012-01-19T03:23:42Z
down regulation of hemostasis
down-regulation of hemostasis
downregulation of hemostasis
inhibition of hemostasis
biological_process
GO:1900047
negative regulation of hemostasis
Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.
GOC:TermGenie
down regulation of hemostasis
GOC:TermGenie
down-regulation of hemostasis
GOC:TermGenie
downregulation of hemostasis
GOC:TermGenie
inhibition of hemostasis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of hemostasis.
jl
2012-01-19T03:23:45Z
up regulation of hemostasis
up-regulation of hemostasis
upregulation of hemostasis
activation of hemostasis
biological_process
GO:1900048
positive regulation of hemostasis
Any process that activates or increases the frequency, rate or extent of hemostasis.
GOC:TermGenie
up regulation of hemostasis
GOC:TermGenie
up-regulation of hemostasis
GOC:TermGenie
upregulation of hemostasis
GOC:TermGenie
activation of hemostasis
GOC:TermGenie
Any regulation of signal transduction that takes place in the extracellular region.
bf
2012-02-22T10:21:48Z
regulation of signaling pathway in extracellular region
regulation of signalling pathway in extracellular region
biological_process
GO:1900115
extracellular regulation of signal transduction
Any regulation of signal transduction that takes place in the extracellular region.
GOC:TermGenie
GOC:signaling
regulation of signaling pathway in extracellular region
GOC:TermGenie
regulation of signalling pathway in extracellular region
GOC:TermGenie
Any negative regulation of signal transduction that takes place in extracellular region.
bf
2012-02-22T10:27:56Z
down regulation of signal transduction in extracellular region
down-regulation of signal transduction in extracellular region
downregulation of signal transduction in extracellular region
negative regulation of signaling pathway in extracellular region
negative regulation of signalling pathway in extracellular region
extracellular inhibition of signaling pathway
inhibition of signal transduction in extracellular region
biological_process
GO:1900116
extracellular negative regulation of signal transduction
Any negative regulation of signal transduction that takes place in extracellular region.
GOC:TermGenie
GOC:signaling
down regulation of signal transduction in extracellular region
GOC:TermGenie
down-regulation of signal transduction in extracellular region
GOC:TermGenie
downregulation of signal transduction in extracellular region
GOC:TermGenie
negative regulation of signaling pathway in extracellular region
GOC:TermGenie
negative regulation of signalling pathway in extracellular region
GOC:TermGenie
extracellular inhibition of signaling pathway
GOC:bf
inhibition of signal transduction in extracellular region
GOC:TermGenie
Any process that modulates the frequency, rate or extent of execution phase of apoptosis.
pr
2012-02-22T11:26:20Z
biological_process
GO:1900117
regulation of execution phase of apoptosis
Any process that modulates the frequency, rate or extent of execution phase of apoptosis.
GOC:TermGenie
GOC:mtg_apoptosis
Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
pr
2012-02-22T11:26:24Z
down regulation of execution phase of apoptosis
down-regulation of execution phase of apoptosis
downregulation of execution phase of apoptosis
inhibition of execution phase of apoptosis
biological_process
GO:1900118
negative regulation of execution phase of apoptosis
Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
GOC:TermGenie
GOC:mtg_apoptosis
down regulation of execution phase of apoptosis
GOC:TermGenie
down-regulation of execution phase of apoptosis
GOC:TermGenie
downregulation of execution phase of apoptosis
GOC:TermGenie
inhibition of execution phase of apoptosis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.
pr
2012-02-22T11:26:27Z
up regulation of execution phase of apoptosis
up-regulation of execution phase of apoptosis
upregulation of execution phase of apoptosis
activation of execution phase of apoptosis
biological_process
GO:1900119
positive regulation of execution phase of apoptosis
Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.
GOC:TermGenie
GOC:mtg_apoptosis
up regulation of execution phase of apoptosis
GOC:TermGenie
up-regulation of execution phase of apoptosis
GOC:TermGenie
upregulation of execution phase of apoptosis
GOC:TermGenie
activation of execution phase of apoptosis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.
bf
2012-02-22T11:40:53Z
regulation of receptor ligand
biological_process
GO:1900120
regulation of receptor binding
Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.
GOC:TermGenie
GOC:signaling
regulation of receptor ligand
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.
bf
2012-02-22T11:40:57Z
down regulation of receptor binding
down-regulation of receptor binding
downregulation of receptor binding
inhibition of receptor binding
inhibition of receptor ligand
biological_process
down regulation of receptor-associated protein activity
GO:1900121
negative regulation of receptor binding
Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.
GOC:TermGenie
GOC:signaling
down regulation of receptor binding
GOC:TermGenie
down-regulation of receptor binding
GOC:TermGenie
downregulation of receptor binding
GOC:TermGenie
inhibition of receptor binding
GOC:TermGenie
inhibition of receptor ligand
GOC:TermGenie
down regulation of receptor-associated protein activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.
bf
2012-02-22T11:41:00Z
up regulation of receptor binding
upregulation of receptor binding
activation of receptor binding
biological_process
GO:1900122
positive regulation of receptor binding
Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.
GOC:TermGenie
GOC:signaling
up regulation of receptor binding
GOC:TermGenie
upregulation of receptor binding
GOC:TermGenie
activation of receptor binding
GOC:TermGenie
Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure.
bf
2012-03-08T10:51:50Z
DNA organisation in plastid
DNA organization in plastid
plastidial DNA packaging
biological_process
GO:1900160
plastid DNA packaging
Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure.
GOC:TermGenie
GOC:emb
PMID:12081370
DNA organisation in plastid
GOC:TermGenie
DNA organization in plastid
GOC:TermGenie
plastidial DNA packaging
GOC:emb
Any process that modulates the frequency, rate or extent of single-species biofilm formation.
di
2012-03-19T12:42:04Z
biological_process
GO:1900190
regulation of single-species biofilm formation
Any process that modulates the frequency, rate or extent of single-species biofilm formation.
GOC:TermGenie
GOC:di
Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
di
2012-03-19T12:42:13Z
down regulation of single-species biofilm formation
down-regulation of single-species biofilm formation
downregulation of single-species biofilm formation
inhibition of single-species biofilm formation
biological_process
GO:1900191
negative regulation of single-species biofilm formation
Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
GOC:TermGenie
GOC:di
down regulation of single-species biofilm formation
GOC:TermGenie
down-regulation of single-species biofilm formation
GOC:TermGenie
downregulation of single-species biofilm formation
GOC:TermGenie
inhibition of single-species biofilm formation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.
di
2012-03-19T12:42:21Z
up regulation of single-species biofilm formation
up-regulation of single-species biofilm formation
upregulation of single-species biofilm formation
activation of single-species biofilm formation
biological_process
GO:1900192
positive regulation of single-species biofilm formation
Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.
GOC:TermGenie
GOC:di
up regulation of single-species biofilm formation
GOC:TermGenie
up-regulation of single-species biofilm formation
GOC:TermGenie
upregulation of single-species biofilm formation
GOC:TermGenie
activation of single-species biofilm formation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
di
2012-03-23T04:40:35Z
biological_process
GO:1900231
regulation of single-species biofilm formation on inanimate substrate
Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GOC:TermGenie
GOC:di
Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
di
2012-03-23T04:40:45Z
down regulation of single-species biofilm formation on inanimate substrate
down-regulation of single-species biofilm formation on inanimate substrate
downregulation of single-species biofilm formation on inanimate substrate
inhibition of single-species biofilm formation on inanimate substrate
biological_process
GO:1900232
negative regulation of single-species biofilm formation on inanimate substrate
Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GOC:TermGenie
GOC:di
down regulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
down-regulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
downregulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
inhibition of single-species biofilm formation on inanimate substrate
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
di
2012-03-23T04:40:53Z
up regulation of single-species biofilm formation on inanimate substrate
up-regulation of single-species biofilm formation on inanimate substrate
upregulation of single-species biofilm formation on inanimate substrate
activation of single-species biofilm formation on inanimate substrate
biological_process
GO:1900233
positive regulation of single-species biofilm formation on inanimate substrate
Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GOC:TermGenie
GOC:di
up regulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
up-regulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
upregulation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
activation of single-species biofilm formation on inanimate substrate
GOC:TermGenie
Any process that modulates the frequency, rate or extent of RNA interference.
kmv
2012-04-13T08:28:39Z
regulation of RNAi
regulation of posttranscriptional gene silencing by siRNA
biological_process
GO:1900368
regulation of RNA interference
Any process that modulates the frequency, rate or extent of RNA interference.
GOC:TermGenie
GOC:kmv
PMID:22412382
regulation of RNAi
GOC:TermGenie
regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference.
kmv
2012-04-13T08:28:50Z
down regulation of RNA interference
down regulation of RNAi
down regulation of posttranscriptional gene silencing by siRNA
down-regulation of RNA interference
down-regulation of RNAi
down-regulation of posttranscriptional gene silencing by siRNA
downregulation of RNA interference
downregulation of RNAi
downregulation of posttranscriptional gene silencing by siRNA
inhibition of RNAi
inhibition of posttranscriptional gene silencing by siRNA
negative regulation of RNAi
negative regulation of posttranscriptional gene silencing by siRNA
inhibition of RNA interference
biological_process
GO:1900369
negative regulation of RNA interference
Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference.
GOC:TermGenie
GOC:kmv
PMID:22412382
down regulation of RNA interference
GOC:TermGenie
down regulation of RNAi
GOC:TermGenie
down regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
down-regulation of RNA interference
GOC:TermGenie
down-regulation of RNAi
GOC:TermGenie
down-regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
downregulation of RNA interference
GOC:TermGenie
downregulation of RNAi
GOC:TermGenie
downregulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
inhibition of RNAi
GOC:TermGenie
inhibition of posttranscriptional gene silencing by siRNA
GOC:TermGenie
negative regulation of RNAi
GOC:TermGenie
negative regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
inhibition of RNA interference
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of RNA interference.
kmv
2012-04-13T08:29:00Z
activation of RNAi
activation of posttranscriptional gene silencing by siRNA
positive regulation of RNAi
positive regulation of posttranscriptional gene silencing by siRNA
up regulation of RNA interference
up regulation of RNAi
up regulation of posttranscriptional gene silencing by siRNA
up-regulation of RNA interference
up-regulation of RNAi
up-regulation of posttranscriptional gene silencing by siRNA
upregulation of RNA interference
upregulation of RNAi
upregulation of posttranscriptional gene silencing by siRNA
activation of RNA interference
biological_process
GO:1900370
positive regulation of RNA interference
Any process that activates or increases the frequency, rate or extent of RNA interference.
GOC:TermGenie
GOC:kmv
PMID:22412382
activation of RNAi
GOC:TermGenie
activation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
positive regulation of RNAi
GOC:TermGenie
positive regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
up regulation of RNA interference
GOC:TermGenie
up regulation of RNAi
GOC:TermGenie
up regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
up-regulation of RNA interference
GOC:TermGenie
up-regulation of RNAi
GOC:TermGenie
up-regulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
upregulation of RNA interference
GOC:TermGenie
upregulation of RNAi
GOC:TermGenie
upregulation of posttranscriptional gene silencing by siRNA
GOC:TermGenie
activation of RNA interference
GOC:TermGenie
Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.
krc
2012-04-17T12:32:07Z
regulation of purine nucleotide anabolism
regulation of purine nucleotide biosynthesis
regulation of purine nucleotide formation
regulation of purine nucleotide synthesis
biological_process
GO:1900371
regulation of purine nucleotide biosynthetic process
Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.
GOC:TermGenie
GOC:go_curators
regulation of purine nucleotide anabolism
GOC:TermGenie
regulation of purine nucleotide biosynthesis
GOC:TermGenie
regulation of purine nucleotide formation
GOC:TermGenie
regulation of purine nucleotide synthesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.
krc
2012-04-17T12:32:27Z
down regulation of purine nucleotide anabolism
down regulation of purine nucleotide biosynthesis
down regulation of purine nucleotide biosynthetic process
down regulation of purine nucleotide formation
down regulation of purine nucleotide synthesis
down-regulation of purine nucleotide anabolism
down-regulation of purine nucleotide biosynthesis
down-regulation of purine nucleotide biosynthetic process
down-regulation of purine nucleotide formation
down-regulation of purine nucleotide synthesis
downregulation of purine nucleotide anabolism
downregulation of purine nucleotide biosynthesis
downregulation of purine nucleotide biosynthetic process
downregulation of purine nucleotide formation
downregulation of purine nucleotide synthesis
inhibition of purine nucleotide anabolism
inhibition of purine nucleotide biosynthesis
inhibition of purine nucleotide formation
inhibition of purine nucleotide synthesis
negative regulation of purine nucleotide anabolism
negative regulation of purine nucleotide biosynthesis
negative regulation of purine nucleotide formation
negative regulation of purine nucleotide synthesis
inhibition of purine nucleotide biosynthetic process
biological_process
GO:1900372
negative regulation of purine nucleotide biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.
GOC:TermGenie
GOC:go_curators
down regulation of purine nucleotide anabolism
GOC:TermGenie
down regulation of purine nucleotide biosynthesis
GOC:TermGenie
down regulation of purine nucleotide biosynthetic process
GOC:TermGenie
down regulation of purine nucleotide formation
GOC:TermGenie
down regulation of purine nucleotide synthesis
GOC:TermGenie
down-regulation of purine nucleotide anabolism
GOC:TermGenie
down-regulation of purine nucleotide biosynthesis
GOC:TermGenie
down-regulation of purine nucleotide biosynthetic process
GOC:TermGenie
down-regulation of purine nucleotide formation
GOC:TermGenie
down-regulation of purine nucleotide synthesis
GOC:TermGenie
downregulation of purine nucleotide anabolism
GOC:TermGenie
downregulation of purine nucleotide biosynthesis
GOC:TermGenie
downregulation of purine nucleotide biosynthetic process
GOC:TermGenie
downregulation of purine nucleotide formation
GOC:TermGenie
downregulation of purine nucleotide synthesis
GOC:TermGenie
inhibition of purine nucleotide anabolism
GOC:TermGenie
inhibition of purine nucleotide biosynthesis
GOC:TermGenie
inhibition of purine nucleotide formation
GOC:TermGenie
inhibition of purine nucleotide synthesis
GOC:TermGenie
negative regulation of purine nucleotide anabolism
GOC:TermGenie
negative regulation of purine nucleotide biosynthesis
GOC:TermGenie
negative regulation of purine nucleotide formation
GOC:TermGenie
negative regulation of purine nucleotide synthesis
GOC:TermGenie
inhibition of purine nucleotide biosynthetic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.
krc
2012-04-17T12:32:37Z
activation of purine nucleotide anabolism
activation of purine nucleotide biosynthesis
activation of purine nucleotide formation
activation of purine nucleotide synthesis
positive regulation of purine nucleotide anabolism
positive regulation of purine nucleotide biosynthesis
positive regulation of purine nucleotide formation
positive regulation of purine nucleotide synthesis
up regulation of purine nucleotide anabolism
up regulation of purine nucleotide biosynthesis
up regulation of purine nucleotide biosynthetic process
up regulation of purine nucleotide formation
up regulation of purine nucleotide synthesis
up-regulation of purine nucleotide anabolism
up-regulation of purine nucleotide biosynthesis
up-regulation of purine nucleotide biosynthetic process
up-regulation of purine nucleotide formation
up-regulation of purine nucleotide synthesis
upregulation of purine nucleotide anabolism
upregulation of purine nucleotide biosynthesis
upregulation of purine nucleotide biosynthetic process
upregulation of purine nucleotide formation
upregulation of purine nucleotide synthesis
activation of purine nucleotide biosynthetic process
biological_process
GO:1900373
positive regulation of purine nucleotide biosynthetic process
Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.
GOC:TermGenie
GOC:go_curators
activation of purine nucleotide anabolism
GOC:TermGenie
activation of purine nucleotide biosynthesis
GOC:TermGenie
activation of purine nucleotide formation
GOC:TermGenie
activation of purine nucleotide synthesis
GOC:TermGenie
positive regulation of purine nucleotide anabolism
GOC:TermGenie
positive regulation of purine nucleotide biosynthesis
GOC:TermGenie
positive regulation of purine nucleotide formation
GOC:TermGenie
positive regulation of purine nucleotide synthesis
GOC:TermGenie
up regulation of purine nucleotide anabolism
GOC:TermGenie
up regulation of purine nucleotide biosynthesis
GOC:TermGenie
up regulation of purine nucleotide biosynthetic process
GOC:TermGenie
up regulation of purine nucleotide formation
GOC:TermGenie
up regulation of purine nucleotide synthesis
GOC:TermGenie
up-regulation of purine nucleotide anabolism
GOC:TermGenie
up-regulation of purine nucleotide biosynthesis
GOC:TermGenie
up-regulation of purine nucleotide biosynthetic process
GOC:TermGenie
up-regulation of purine nucleotide formation
GOC:TermGenie
up-regulation of purine nucleotide synthesis
GOC:TermGenie
upregulation of purine nucleotide anabolism
GOC:TermGenie
upregulation of purine nucleotide biosynthesis
GOC:TermGenie
upregulation of purine nucleotide biosynthetic process
GOC:TermGenie
upregulation of purine nucleotide formation
GOC:TermGenie
upregulation of purine nucleotide synthesis
GOC:TermGenie
activation of purine nucleotide biosynthetic process
GOC:TermGenie
OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.
pr
2012-04-18T12:01:19Z
biological_process
GO:1900387
This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter
true
OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.
GOC:BHF
GOC:TermGenie
PMID:15737616
OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport.
mah
2012-04-18T04:20:25Z
biological_process
GO:1900392
This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter
true
OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport.
GOC:TermGenie
GOC:mah
PMID:17446861
OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process.
mah
2012-04-20T02:45:27Z
regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter
biological_process
GO:1900402
This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
true
OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process.
GOC:TermGenie
GOC:mah
PMID:16408318
regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process.
krc
2012-04-20T10:13:58Z
activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
biological_process
GO:1900418
This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
true
OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process.
GOC:TermGenie
GOC:curators
PMID:17573544
activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
GOC:TermGenie
Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
krc
2012-05-11T05:43:15Z
regulation of purine nucleotide metabolism
regulation of purine metabolic process
regulation of purine metabolism
biological_process
GO:1900542
regulation of purine nucleotide metabolic process
Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
GOC:TermGenie
regulation of purine nucleotide metabolism
GOC:TermGenie
regulation of purine metabolic process
GOC:TermGenie
regulation of purine metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
krc
2012-05-11T05:44:21Z
down regulation of purine nucleotide metabolic process
down regulation of purine nucleotide metabolism
down-regulation of purine nucleotide metabolic process
down-regulation of purine nucleotide metabolism
downregulation of purine nucleotide metabolic process
downregulation of purine nucleotide metabolism
negative regulation of purine nucleotide metabolism
down regulation of purine metabolic process
down regulation of purine metabolism
down-regulation of purine metabolic process
down-regulation of purine metabolism
downregulation of purine metabolic process
downregulation of purine metabolism
inhibition of purine metabolic process
inhibition of purine metabolism
inhibition of purine nucleotide metabolic process
inhibition of purine nucleotide metabolism
negative regulation of purine metabolic process
negative regulation of purine metabolism
biological_process
GO:1900543
negative regulation of purine nucleotide metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
GOC:TermGenie
down regulation of purine nucleotide metabolic process
GOC:TermGenie
down regulation of purine nucleotide metabolism
GOC:TermGenie
down-regulation of purine nucleotide metabolic process
GOC:TermGenie
down-regulation of purine nucleotide metabolism
GOC:TermGenie
downregulation of purine nucleotide metabolic process
GOC:TermGenie
downregulation of purine nucleotide metabolism
GOC:TermGenie
negative regulation of purine nucleotide metabolism
GOC:TermGenie
down regulation of purine metabolic process
GOC:TermGenie
down regulation of purine metabolism
GOC:TermGenie
down-regulation of purine metabolic process
GOC:TermGenie
down-regulation of purine metabolism
GOC:TermGenie
downregulation of purine metabolic process
GOC:TermGenie
downregulation of purine metabolism
GOC:TermGenie
inhibition of purine metabolic process
GOC:TermGenie
inhibition of purine metabolism
GOC:TermGenie
inhibition of purine nucleotide metabolic process
GOC:TermGenie
inhibition of purine nucleotide metabolism
GOC:TermGenie
negative regulation of purine metabolic process
GOC:TermGenie
negative regulation of purine metabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.
krc
2012-05-11T05:44:43Z
positive regulation of purine nucleotide metabolism
up regulation of purine nucleotide metabolic process
up regulation of purine nucleotide metabolism
up-regulation of purine nucleotide metabolic process
up-regulation of purine nucleotide metabolism
upregulation of purine nucleotide metabolic process
upregulation of purine nucleotide metabolism
activation of purine metabolic process
activation of purine metabolism
activation of purine nucleotide metabolic process
activation of purine nucleotide metabolism
positive regulation of purine metabolic process
positive regulation of purine metabolism
up regulation of purine metabolic process
up regulation of purine metabolism
up-regulation of purine metabolic process
up-regulation of purine metabolism
upregulation of purine metabolic process
upregulation of purine metabolism
biological_process
GO:1900544
positive regulation of purine nucleotide metabolic process
Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.
GOC:TermGenie
positive regulation of purine nucleotide metabolism
GOC:TermGenie
up regulation of purine nucleotide metabolic process
GOC:TermGenie
up regulation of purine nucleotide metabolism
GOC:TermGenie
up-regulation of purine nucleotide metabolic process
GOC:TermGenie
up-regulation of purine nucleotide metabolism
GOC:TermGenie
upregulation of purine nucleotide metabolic process
GOC:TermGenie
upregulation of purine nucleotide metabolism
GOC:TermGenie
activation of purine metabolic process
GOC:TermGenie
activation of purine metabolism
GOC:TermGenie
activation of purine nucleotide metabolic process
GOC:TermGenie
activation of purine nucleotide metabolism
GOC:TermGenie
positive regulation of purine metabolic process
GOC:TermGenie
positive regulation of purine metabolism
GOC:TermGenie
up regulation of purine metabolic process
GOC:TermGenie
up regulation of purine metabolism
GOC:TermGenie
up-regulation of purine metabolic process
GOC:TermGenie
up-regulation of purine metabolism
GOC:TermGenie
upregulation of purine metabolic process
GOC:TermGenie
upregulation of purine metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of response to salt stress.
dhl
2012-06-14T05:41:19Z
regulation of response to ionic osmotic stress
regulation of salinity response
biological_process
GO:1901000
regulation of response to salt stress
Any process that modulates the frequency, rate or extent of response to salt stress.
GOC:TermGenie
PMID:22627139
regulation of response to ionic osmotic stress
GOC:TermGenie
regulation of salinity response
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.
dhl
2012-06-14T05:41:43Z
down regulation of response to ionic osmotic stress
down regulation of response to salt stress
down regulation of salinity response
down-regulation of response to ionic osmotic stress
down-regulation of response to salt stress
down-regulation of salinity response
downregulation of response to ionic osmotic stress
downregulation of response to salt stress
downregulation of salinity response
inhibition of response to ionic osmotic stress
inhibition of salinity response
negative regulation of response to ionic osmotic stress
negative regulation of salinity response
inhibition of response to salt stress
biological_process
GO:1901001
negative regulation of response to salt stress
Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.
GOC:TermGenie
PMID:22627139
down regulation of response to ionic osmotic stress
GOC:TermGenie
down regulation of response to salt stress
GOC:TermGenie
down regulation of salinity response
GOC:TermGenie
down-regulation of response to ionic osmotic stress
GOC:TermGenie
down-regulation of response to salt stress
GOC:TermGenie
down-regulation of salinity response
GOC:TermGenie
downregulation of response to ionic osmotic stress
GOC:TermGenie
downregulation of response to salt stress
GOC:TermGenie
downregulation of salinity response
GOC:TermGenie
inhibition of response to ionic osmotic stress
GOC:TermGenie
inhibition of salinity response
GOC:TermGenie
negative regulation of response to ionic osmotic stress
GOC:TermGenie
negative regulation of salinity response
GOC:TermGenie
inhibition of response to salt stress
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of response to salt stress.
dhl
2012-06-14T05:41:50Z
activation of response to ionic osmotic stress
activation of salinity response
positive regulation of response to ionic osmotic stress
positive regulation of salinity response
up regulation of response to ionic osmotic stress
up regulation of response to salt stress
up regulation of salinity response
up-regulation of response to ionic osmotic stress
up-regulation of response to salt stress
up-regulation of salinity response
upregulation of response to ionic osmotic stress
upregulation of response to salt stress
upregulation of salinity response
activation of response to salt stress
biological_process
GO:1901002
positive regulation of response to salt stress
Any process that activates or increases the frequency, rate or extent of response to salt stress.
GOC:TermGenie
PMID:22627139
activation of response to ionic osmotic stress
GOC:TermGenie
activation of salinity response
GOC:TermGenie
positive regulation of response to ionic osmotic stress
GOC:TermGenie
positive regulation of salinity response
GOC:TermGenie
up regulation of response to ionic osmotic stress
GOC:TermGenie
up regulation of response to salt stress
GOC:TermGenie
up regulation of salinity response
GOC:TermGenie
up-regulation of response to ionic osmotic stress
GOC:TermGenie
up-regulation of response to salt stress
GOC:TermGenie
up-regulation of salinity response
GOC:TermGenie
upregulation of response to ionic osmotic stress
GOC:TermGenie
upregulation of response to salt stress
GOC:TermGenie
upregulation of salinity response
GOC:TermGenie
activation of response to salt stress
GOC:TermGenie
The chemical reactions and pathways involving carbohydrate derivative.
bf
2012-07-12T04:05:09Z
carbohydrate derivative metabolism
biological_process
GO:1901135
carbohydrate derivative metabolic process
The chemical reactions and pathways involving carbohydrate derivative.
GOC:TermGenie
carbohydrate derivative metabolism
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
bf
2012-07-12T04:05:39Z
carbohydrate derivative anabolism
carbohydrate derivative biosynthesis
carbohydrate derivative formation
carbohydrate derivative synthesis
biological_process
GO:1901137
carbohydrate derivative biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GOC:TermGenie
carbohydrate derivative anabolism
GOC:TermGenie
carbohydrate derivative biosynthesis
GOC:TermGenie
carbohydrate derivative formation
GOC:TermGenie
carbohydrate derivative synthesis
GOC:TermGenie
Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
bf
2012-07-16T03:29:30Z
expression of extracellular matrix proteins
biological_process
extracellular matrix protein production
GO:1901148
gene expression involved in extracellular matrix organization
Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
GOC:TermGenie
GOC:pg
PMID:18668558
expression of extracellular matrix proteins
GOC:bf
extracellular matrix protein production
GOC:pg
The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.
bf
2012-08-20T12:33:45Z
nucleoside phosphate anabolism
nucleoside phosphate biosynthesis
nucleoside phosphate formation
nucleoside phosphate synthesis
biological_process
GO:1901293
nucleoside phosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.
GOC:TermGenie
nucleoside phosphate anabolism
GOC:TermGenie
nucleoside phosphate biosynthesis
GOC:TermGenie
nucleoside phosphate formation
GOC:TermGenie
nucleoside phosphate synthesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of flagellated sperm motility.
hjd
2012-08-22T20:50:14Z
regulation of sperm motility
regulation of sperm movement
biological_process
GO:1901317
regulation of flagellated sperm motility
Any process that modulates the frequency, rate or extent of flagellated sperm motility.
GOC:TermGenie
GOC:cilia
GOC:krc
regulation of sperm movement
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.
hjd
2012-08-22T20:50:35Z
down regulation of sperm motility
down regulation of sperm movement
down-regulation of sperm motility
down-regulation of sperm movement
downregulation of sperm motility
downregulation of sperm movement
inhibition of sperm movement
negative regulation of sperm motility
negative regulation of sperm movement
inhibition of sperm motility
biological_process
GO:1901318
negative regulation of flagellated sperm motility
Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.
GOC:TermGenie
GOC:cilia
GOC:krc
down regulation of sperm motility
GOC:TermGenie
down regulation of sperm movement
GOC:TermGenie
down-regulation of sperm motility
GOC:TermGenie
down-regulation of sperm movement
GOC:TermGenie
downregulation of sperm motility
GOC:TermGenie
downregulation of sperm movement
GOC:TermGenie
inhibition of sperm movement
GOC:TermGenie
negative regulation of sperm movement
GOC:TermGenie
inhibition of sperm motility
GOC:TermGenie
Any process that modulates the frequency, rate or extent of vasculature development.
bf
2012-09-06T09:16:15Z
biological_process
regulation of vascular system development
GO:1901342
regulation of vasculature development
Any process that modulates the frequency, rate or extent of vasculature development.
GOC:TermGenie
regulation of vascular system development
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.
bf
2012-09-06T09:17:24Z
down regulation of vasculature development
down-regulation of vasculature development
downregulation of vasculature development
inhibition of vasculature development
biological_process
down regulation of vascular system development
down-regulation of vascular system development
downregulation of vascular system development
inhibition of vascular system development
negative regulation of vascular system development
GO:1901343
negative regulation of vasculature development
Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.
GOC:TermGenie
down regulation of vasculature development
GOC:TermGenie
down-regulation of vasculature development
GOC:TermGenie
downregulation of vasculature development
GOC:TermGenie
inhibition of vasculature development
GOC:TermGenie
down regulation of vascular system development
GOC:TermGenie
down-regulation of vascular system development
GOC:TermGenie
downregulation of vascular system development
GOC:TermGenie
inhibition of vascular system development
GOC:TermGenie
negative regulation of vascular system development
GOC:TermGenie
The chemical reactions and pathways involving organic cyclic compound.
bf
2012-09-14T09:03:51Z
organic cyclic compound metabolism
biological_process
GO:1901360
organic cyclic compound metabolic process
The chemical reactions and pathways involving organic cyclic compound.
GOC:TermGenie
organic cyclic compound metabolism
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of organic cyclic compound.
bf
2012-09-14T09:05:22Z
organic cyclic compound anabolism
organic cyclic compound biosynthesis
organic cyclic compound formation
organic cyclic compound synthesis
biological_process
GO:1901362
organic cyclic compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organic cyclic compound.
GOC:TermGenie
organic cyclic compound anabolism
GOC:TermGenie
organic cyclic compound biosynthesis
GOC:TermGenie
organic cyclic compound formation
GOC:TermGenie
organic cyclic compound synthesis
GOC:TermGenie
Interacting selectively and non-covalently with heterocyclic compound.
bf
2012-09-14T13:53:50Z
molecular_function
GO:1901363
heterocyclic compound binding
Interacting selectively and non-covalently with heterocyclic compound.
GOC:TermGenie
Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.
tt
2012-10-01T14:34:03Z
regulation of tetrapyrrole metabolism
biological_process
GO:1901401
regulation of tetrapyrrole metabolic process
Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.
GOC:TermGenie
GOC:mengo_curators
regulation of tetrapyrrole metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.
tt
2012-10-01T14:35:11Z
down regulation of tetrapyrrole metabolic process
down regulation of tetrapyrrole metabolism
down-regulation of tetrapyrrole metabolic process
down-regulation of tetrapyrrole metabolism
downregulation of tetrapyrrole metabolic process
downregulation of tetrapyrrole metabolism
inhibition of tetrapyrrole metabolism
negative regulation of tetrapyrrole metabolism
inhibition of tetrapyrrole metabolic process
biological_process
GO:1901402
negative regulation of tetrapyrrole metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.
GOC:TermGenie
GOC:mengo_curators
down regulation of tetrapyrrole metabolic process
GOC:TermGenie
down regulation of tetrapyrrole metabolism
GOC:TermGenie
down-regulation of tetrapyrrole metabolic process
GOC:TermGenie
down-regulation of tetrapyrrole metabolism
GOC:TermGenie
downregulation of tetrapyrrole metabolic process
GOC:TermGenie
downregulation of tetrapyrrole metabolism
GOC:TermGenie
inhibition of tetrapyrrole metabolism
GOC:TermGenie
negative regulation of tetrapyrrole metabolism
GOC:TermGenie
inhibition of tetrapyrrole metabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.
tt
2012-10-01T14:35:29Z
activation of tetrapyrrole metabolism
positive regulation of tetrapyrrole metabolism
up regulation of tetrapyrrole metabolic process
up regulation of tetrapyrrole metabolism
up-regulation of tetrapyrrole metabolic process
up-regulation of tetrapyrrole metabolism
upregulation of tetrapyrrole metabolic process
upregulation of tetrapyrrole metabolism
activation of tetrapyrrole metabolic process
biological_process
GO:1901403
positive regulation of tetrapyrrole metabolic process
Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.
GOC:TermGenie
GOC:mengo_curators
activation of tetrapyrrole metabolism
GOC:TermGenie
positive regulation of tetrapyrrole metabolism
GOC:TermGenie
up regulation of tetrapyrrole metabolic process
GOC:TermGenie
up regulation of tetrapyrrole metabolism
GOC:TermGenie
up-regulation of tetrapyrrole metabolic process
GOC:TermGenie
up-regulation of tetrapyrrole metabolism
GOC:TermGenie
upregulation of tetrapyrrole metabolic process
GOC:TermGenie
upregulation of tetrapyrrole metabolism
GOC:TermGenie
activation of tetrapyrrole metabolic process
GOC:TermGenie
Any process that modulates the frequency, rate or extent of response to alcohol.
tt
2012-10-01T16:52:13Z
biological_process
GO:1901419
regulation of response to alcohol
Any process that modulates the frequency, rate or extent of response to alcohol.
GOC:TermGenie
GOC:mengo_curators
Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.
tt
2012-10-01T16:53:25Z
down regulation of response to alcohol
down-regulation of response to alcohol
downregulation of response to alcohol
inhibition of response to alcohol
biological_process
GO:1901420
negative regulation of response to alcohol
Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.
GOC:TermGenie
GOC:mengo_curators
down regulation of response to alcohol
GOC:TermGenie
down-regulation of response to alcohol
GOC:TermGenie
downregulation of response to alcohol
GOC:TermGenie
inhibition of response to alcohol
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of response to alcohol.
tt
2012-10-01T16:53:42Z
up regulation of response to alcohol
up-regulation of response to alcohol
upregulation of response to alcohol
activation of response to alcohol
biological_process
GO:1901421
positive regulation of response to alcohol
Any process that activates or increases the frequency, rate or extent of response to alcohol.
GOC:TermGenie
GOC:mengo_curators
up regulation of response to alcohol
GOC:TermGenie
up-regulation of response to alcohol
GOC:TermGenie
upregulation of response to alcohol
GOC:TermGenie
activation of response to alcohol
GOC:TermGenie
Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.
al
2012-10-19T08:25:05Z
positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus
stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
biological_process
activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus
up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:1901522
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.
GOC:TermGenie
PMID:22840777
positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GOC:TermGenie
The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression.
jl
2012-10-25T14:53:43Z
DNA methylation or demethylation involved in embryogenesis
DNA methylation or demethylation involved in embryonal development
changes in DNA methylation involved in embryo development
changes in DNA methylation involved in embryogenesis
biological_process
changes in DNA methylation involved in embryonal development
GO:1901538
changes to DNA methylation involved in embryo development
The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression.
GOC:TermGenie
DNA methylation or demethylation involved in embryogenesis
GOC:TermGenie
DNA methylation or demethylation involved in embryonal development
GOC:TermGenie
changes in DNA methylation involved in embryo development
GOC:TermGenie
changes in DNA methylation involved in embryogenesis
GOC:TermGenie
changes in DNA methylation involved in embryonal development
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.
hp
2012-11-02T09:43:23Z
response to acetaminophen
biological_process
GO:1901554
response to paracetamol
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.
hp
2012-11-02T09:46:08Z
biological_process
GO:1901555
response to paclitaxel
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.
hp
2012-11-02T09:46:13Z
biological_process
GO:1901556
response to candesartan
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.
hp
2012-11-02T09:46:20Z
biological_process
GO:1901557
response to fenofibrate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.
hp
2012-11-02T09:46:24Z
biological_process
GO:1901558
response to metformin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.
hp
2012-11-02T09:46:28Z
biological_process
GO:1901559
response to ribavirin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
mah
2012-11-02T15:32:45Z
response to CPT
biological_process
GO:1901563
response to camptothecin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
GOC:TermGenie
response to CPT
GOC:mah
The chemical reactions and pathways involving organonitrogen compound.
pr
2012-11-04T15:17:52Z
organonitrogen compound metabolism
biological_process
GO:1901564
organonitrogen compound metabolic process
The chemical reactions and pathways involving organonitrogen compound.
GOC:TermGenie
GOC:pr
organonitrogen compound metabolism
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of organonitrogen compound.
pr
2012-11-04T15:18:00Z
organonitrogen compound anabolism
organonitrogen compound biosynthesis
organonitrogen compound formation
organonitrogen compound synthesis
biological_process
GO:1901566
organonitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organonitrogen compound.
GOC:TermGenie
GOC:pr
organonitrogen compound anabolism
GOC:TermGenie
organonitrogen compound biosynthesis
GOC:TermGenie
organonitrogen compound formation
GOC:TermGenie
organonitrogen compound synthesis
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
pr
2012-11-05T11:04:40Z
organic molecular entity anabolism
organic molecular entity biosynthesis
organic molecular entity biosynthetic process
organic molecular entity formation
organic molecular entity synthesis
organic substance anabolism
organic substance biosynthesis
organic substance formation
organic substance synthesis
biological_process
GO:1901576
organic substance biosynthetic process
The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GOC:TermGenie
GOC:pr
organic molecular entity anabolism
GOC:TermGenie
organic molecular entity biosynthesis
GOC:TermGenie
organic molecular entity formation
GOC:TermGenie
organic molecular entity synthesis
GOC:TermGenie
The chemical reactions and pathways involving organic hydroxy compound.
pr
2012-11-13T12:54:27Z
organic hydroxy compound metabolism
biological_process
GO:1901615
organic hydroxy compound metabolic process
The chemical reactions and pathways involving organic hydroxy compound.
GOC:TermGenie
GOC:pr
organic hydroxy compound metabolism
GOC:TermGenie
A response that results in a state of tolerance to ketone.
pr
2012-11-20T10:55:47Z
GO:1990369
process resulting in tolerance to ketone
biological_process
GO:1901654
response to ketone
A response that results in a state of tolerance to ketone.
GOC:mengo_curators
PMID:23356676
The chemical reactions and pathways involving glycosyl compound.
pr
2012-11-20T14:24:07Z
glycosyl compound metabolism
biological_process
GO:1901657
glycosyl compound metabolic process
The chemical reactions and pathways involving glycosyl compound.
GOC:TermGenie
GOC:pr
glycosyl compound metabolism
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of glycosyl compound.
pr
2012-11-20T14:24:19Z
glycosyl compound anabolism
glycosyl compound biosynthesis
glycosyl compound formation
glycosyl compound synthesis
biological_process
GO:1901659
glycosyl compound biosynthetic process
The chemical reactions and pathways resulting in the formation of glycosyl compound.
GOC:TermGenie
GOC:pr
glycosyl compound anabolism
GOC:TermGenie
glycosyl compound biosynthesis
GOC:TermGenie
glycosyl compound formation
GOC:TermGenie
glycosyl compound synthesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
al
2012-11-22T09:50:00Z
regulation of spindle assembly involved in mitosis
biological_process
GO:1901673
regulation of mitotic spindle assembly
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
pr
2012-12-13T15:06:08Z
response to nitrogen molecular entity
biological_process
GO:1901698
response to nitrogen compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
GOC:TermGenie
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
pr
2012-12-13T15:11:37Z
response to oxygen molecular entity
biological_process
GO:1901700
response to oxygen-containing compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
GOC:TermGenie
GOC:pr
Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
pr
2013-01-10T13:25:39Z
positive regulation of blood platelet aggregation
up regulation of blood platelet aggregation
up regulation of platelet aggregation
up-regulation of blood platelet aggregation
up-regulation of platelet aggregation
upregulation of blood platelet aggregation
upregulation of platelet aggregation
activation of blood platelet aggregation
activation of platelet aggregation
biological_process
activation of thrombocyte aggregation
positive regulation of thrombocyte aggregation
up regulation of thrombocyte aggregation
up-regulation of thrombocyte aggregation
upregulation of thrombocyte aggregation
GO:1901731
positive regulation of platelet aggregation
Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GOC:TermGenie
GOC:fj
positive regulation of blood platelet aggregation
GOC:TermGenie
up regulation of blood platelet aggregation
GOC:TermGenie
up regulation of platelet aggregation
GOC:TermGenie
up-regulation of blood platelet aggregation
GOC:TermGenie
up-regulation of platelet aggregation
GOC:TermGenie
upregulation of blood platelet aggregation
GOC:TermGenie
upregulation of platelet aggregation
GOC:TermGenie
activation of blood platelet aggregation
GOC:TermGenie
activation of platelet aggregation
GOC:TermGenie
activation of thrombocyte aggregation
GOC:TermGenie
positive regulation of thrombocyte aggregation
GOC:TermGenie
up regulation of thrombocyte aggregation
GOC:TermGenie
up-regulation of thrombocyte aggregation
GOC:TermGenie
upregulation of thrombocyte aggregation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of vitamin A metabolic process.
dph
2013-01-11T15:29:43Z
regulation of vitamin A metabolism
biological_process
GO:1901738
regulation of vitamin A metabolic process
Any process that modulates the frequency, rate or extent of vitamin A metabolic process.
GOC:TermGenie
PMID:18093975
regulation of vitamin A metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:04Z
regulation of mitochondrial DNA metabolism
regulation of mtDNA metabolic process
regulation of mtDNA metabolism
biological_process
GO:1901858
regulation of mitochondrial DNA metabolic process
Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
regulation of mitochondrial DNA metabolism
GOC:TermGenie
regulation of mtDNA metabolic process
GOC:TermGenie
regulation of mtDNA metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:09Z
down regulation of mitochondrial DNA metabolic process
down regulation of mitochondrial DNA metabolism
down regulation of mtDNA metabolic process
down regulation of mtDNA metabolism
down-regulation of mitochondrial DNA metabolic process
down-regulation of mitochondrial DNA metabolism
down-regulation of mtDNA metabolic process
down-regulation of mtDNA metabolism
downregulation of mitochondrial DNA metabolic process
downregulation of mitochondrial DNA metabolism
downregulation of mtDNA metabolic process
downregulation of mtDNA metabolism
inhibition of mitochondrial DNA metabolism
inhibition of mtDNA metabolic process
inhibition of mtDNA metabolism
negative regulation of mitochondrial DNA metabolism
negative regulation of mtDNA metabolic process
negative regulation of mtDNA metabolism
inhibition of mitochondrial DNA metabolic process
biological_process
GO:1901859
negative regulation of mitochondrial DNA metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
down regulation of mitochondrial DNA metabolic process
GOC:TermGenie
down regulation of mitochondrial DNA metabolism
GOC:TermGenie
down regulation of mtDNA metabolic process
GOC:TermGenie
down regulation of mtDNA metabolism
GOC:TermGenie
down-regulation of mitochondrial DNA metabolic process
GOC:TermGenie
down-regulation of mitochondrial DNA metabolism
GOC:TermGenie
down-regulation of mtDNA metabolic process
GOC:TermGenie
down-regulation of mtDNA metabolism
GOC:TermGenie
downregulation of mitochondrial DNA metabolic process
GOC:TermGenie
downregulation of mitochondrial DNA metabolism
GOC:TermGenie
downregulation of mtDNA metabolic process
GOC:TermGenie
downregulation of mtDNA metabolism
GOC:TermGenie
inhibition of mitochondrial DNA metabolism
GOC:TermGenie
inhibition of mtDNA metabolic process
GOC:TermGenie
inhibition of mtDNA metabolism
GOC:TermGenie
negative regulation of mitochondrial DNA metabolism
GOC:TermGenie
negative regulation of mtDNA metabolic process
GOC:TermGenie
negative regulation of mtDNA metabolism
GOC:TermGenie
inhibition of mitochondrial DNA metabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:14Z
activation of mitochondrial DNA metabolism
activation of mtDNA metabolic process
activation of mtDNA metabolism
positive regulation of mitochondrial DNA metabolism
positive regulation of mtDNA metabolic process
positive regulation of mtDNA metabolism
up regulation of mitochondrial DNA metabolic process
up regulation of mitochondrial DNA metabolism
up regulation of mtDNA metabolic process
up regulation of mtDNA metabolism
up-regulation of mitochondrial DNA metabolic process
up-regulation of mitochondrial DNA metabolism
up-regulation of mtDNA metabolic process
up-regulation of mtDNA metabolism
upregulation of mitochondrial DNA metabolic process
upregulation of mitochondrial DNA metabolism
upregulation of mtDNA metabolic process
upregulation of mtDNA metabolism
activation of mitochondrial DNA metabolic process
biological_process
GO:1901860
positive regulation of mitochondrial DNA metabolic process
Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
activation of mitochondrial DNA metabolism
GOC:TermGenie
activation of mtDNA metabolic process
GOC:TermGenie
activation of mtDNA metabolism
GOC:TermGenie
positive regulation of mitochondrial DNA metabolism
GOC:TermGenie
positive regulation of mtDNA metabolic process
GOC:TermGenie
positive regulation of mtDNA metabolism
GOC:TermGenie
up regulation of mitochondrial DNA metabolic process
GOC:TermGenie
up regulation of mitochondrial DNA metabolism
GOC:TermGenie
up regulation of mtDNA metabolic process
GOC:TermGenie
up regulation of mtDNA metabolism
GOC:TermGenie
up-regulation of mitochondrial DNA metabolic process
GOC:TermGenie
up-regulation of mitochondrial DNA metabolism
GOC:TermGenie
up-regulation of mtDNA metabolic process
GOC:TermGenie
up-regulation of mtDNA metabolism
GOC:TermGenie
upregulation of mitochondrial DNA metabolic process
GOC:TermGenie
upregulation of mitochondrial DNA metabolism
GOC:TermGenie
upregulation of mtDNA metabolic process
GOC:TermGenie
upregulation of mtDNA metabolism
GOC:TermGenie
activation of mitochondrial DNA metabolic process
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.
hp
2013-02-13T10:14:41Z
biological_process
GO:1901905
response to tamsulosin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cilium assembly.
dph
2013-03-26T18:10:51Z
regulation of ciliogenesis
biological_process
regulation of cilium biogenesis
GO:1902017
regulation of cilium assembly
Any process that modulates the frequency, rate or extent of cilium assembly.
GOC:TermGenie
GOC:cilia
GOC:dph
PMID:17719545
regulation of ciliogenesis
GOC:TermGenie
regulation of cilium biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
dph
2013-03-26T18:10:56Z
down regulation of ciliogenesis
down regulation of cilium assembly
down-regulation of ciliogenesis
down-regulation of cilium assembly
downregulation of ciliogenesis
downregulation of cilium assembly
inhibition of ciliogenesis
negative regulation of ciliogenesis
inhibition of cilium assembly
biological_process
down regulation of cilium biogenesis
down-regulation of cilium biogenesis
downregulation of cilium biogenesis
inhibition of cilium biogenesis
negative regulation of cilium biogenesis
GO:1902018
negative regulation of cilium assembly
Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
GOC:TermGenie
GOC:cilia
GOC:dph
PMID:17719545
down regulation of ciliogenesis
GOC:TermGenie
down regulation of cilium assembly
GOC:TermGenie
down-regulation of ciliogenesis
GOC:TermGenie
down-regulation of cilium assembly
GOC:TermGenie
downregulation of ciliogenesis
GOC:TermGenie
downregulation of cilium assembly
GOC:TermGenie
inhibition of ciliogenesis
GOC:TermGenie
negative regulation of ciliogenesis
GOC:TermGenie
inhibition of cilium assembly
GOC:TermGenie
down regulation of cilium biogenesis
GOC:TermGenie
down-regulation of cilium biogenesis
GOC:TermGenie
downregulation of cilium biogenesis
GOC:TermGenie
inhibition of cilium biogenesis
GOC:TermGenie
negative regulation of cilium biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.
jl
2013-03-27T14:42:38Z
regulation of cilium cell motility
biological_process
regulation of ciliary cell motility
GO:1902019
regulation of cilium-dependent cell motility
Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.
GOC:TermGenie
GOC:cilia
GOC:jl
Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.
jl
2013-03-27T14:42:42Z
down regulation of ciliary cell motility
down-regulation of ciliary cell motility
downregulation of ciliary cell motility
negative regulation of cilium cell motility
inhibition of ciliary cell motility
biological_process
negative regulation of ciliary cell motility
GO:1902020
negative regulation of cilium-dependent cell motility
Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.
GOC:TermGenie
GOC:cilia
GOC:jl
down regulation of ciliary cell motility
GOC:TermGenie
down-regulation of ciliary cell motility
GOC:TermGenie
downregulation of ciliary cell motility
GOC:TermGenie
inhibition of ciliary cell motility
GOC:TermGenie
Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.
kmv
2013-04-16T20:27:18Z
regulation of transcription from Pol II promoter involved in generation of spermatozoa
regulation of transcription from Pol II promoter involved in spermatogenesis
regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa
biological_process
global transcription regulation from Pol II promoter involved in generation of spermatozoa
global transcription regulation from Pol II promoter involved in spermatogenesis
regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa
regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis
regulation of global transcription from Pol II promoter involved in generation of spermatozoa
regulation of global transcription from Pol II promoter involved in spermatogenesis
regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa
regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis
GO:1902064
regulation of transcription from RNA polymerase II promoter involved in spermatogenesis
Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.
GOC:TermGenie
GOC:kmv
PMID:22570621
regulation of transcription from Pol II promoter involved in generation of spermatozoa
GOC:TermGenie
regulation of transcription from Pol II promoter involved in spermatogenesis
GOC:TermGenie
regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa
GOC:TermGenie
global transcription regulation from Pol II promoter involved in generation of spermatozoa
GOC:TermGenie
global transcription regulation from Pol II promoter involved in spermatogenesis
GOC:TermGenie
regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa
GOC:TermGenie
regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis
GOC:TermGenie
regulation of global transcription from Pol II promoter involved in generation of spermatozoa
GOC:TermGenie
regulation of global transcription from Pol II promoter involved in spermatogenesis
GOC:TermGenie
regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa
GOC:TermGenie
regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
mls
2013-04-22T15:41:57Z
response to salinity
biological_process
GO:1902074
response to salt
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
GOC:TermGenie
GOC:mls
PMID:16666921
response to salinity
GOC:mls
Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.
bf
2013-04-29T09:15:25Z
activation of sperm movement
positive regulation of sperm motility
positive regulation of sperm movement
up regulation of sperm motility
up regulation of sperm movement
up-regulation of sperm motility
up-regulation of sperm movement
upregulation of sperm motility
upregulation of sperm movement
activation of sperm motility
biological_process
GO:1902093
positive regulation of flagellated sperm motility
Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.
GOC:TermGenie
GOC:cilia
GOC:jh2
GOC:krc
PMID:7513657
activation of sperm movement
GOC:TermGenie
positive regulation of sperm movement
GOC:TermGenie
up regulation of sperm motility
GOC:TermGenie
up regulation of sperm movement
GOC:TermGenie
up-regulation of sperm motility
GOC:TermGenie
up-regulation of sperm movement
GOC:TermGenie
upregulation of sperm motility
GOC:TermGenie
upregulation of sperm movement
GOC:TermGenie
activation of sperm motility
GOC:TermGenie
Any process that modulates the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:21Z
biological_process
GO:1902115
regulation of organelle assembly
Any process that modulates the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:31Z
down regulation of organelle assembly
down-regulation of organelle assembly
downregulation of organelle assembly
inhibition of organelle assembly
biological_process
GO:1902116
negative regulation of organelle assembly
Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
down regulation of organelle assembly
GOC:TermGenie
down-regulation of organelle assembly
GOC:TermGenie
downregulation of organelle assembly
GOC:TermGenie
inhibition of organelle assembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:36Z
up regulation of organelle assembly
up-regulation of organelle assembly
upregulation of organelle assembly
activation of organelle assembly
biological_process
GO:1902117
positive regulation of organelle assembly
Any process that activates or increases the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
up regulation of organelle assembly
GOC:TermGenie
up-regulation of organelle assembly
GOC:TermGenie
upregulation of organelle assembly
GOC:TermGenie
activation of organelle assembly
GOC:TermGenie
Any process that modulates the frequency, rate or extent of meiotic spindle elongation.
al
2013-05-15T15:15:48Z
regulation of spindle elongation during meiosis
biological_process
GO:1902119
regulation of meiotic spindle elongation
Any process that modulates the frequency, rate or extent of meiotic spindle elongation.
GOC:TermGenie
PMID:23370392
regulation of spindle elongation during meiosis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.
al
2013-05-15T15:15:53Z
down regulation of meiotic spindle elongation
down regulation of spindle elongation during meiosis
down-regulation of meiotic spindle elongation
down-regulation of spindle elongation during meiosis
downregulation of meiotic spindle elongation
downregulation of spindle elongation during meiosis
inhibition of spindle elongation during meiosis
negative regulation of spindle elongation during meiosis
inhibition of meiotic spindle elongation
biological_process
GO:1902120
negative regulation of meiotic spindle elongation
Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.
GOC:TermGenie
PMID:23370392
down regulation of meiotic spindle elongation
GOC:TermGenie
down regulation of spindle elongation during meiosis
GOC:TermGenie
down-regulation of meiotic spindle elongation
GOC:TermGenie
down-regulation of spindle elongation during meiosis
GOC:TermGenie
downregulation of meiotic spindle elongation
GOC:TermGenie
downregulation of spindle elongation during meiosis
GOC:TermGenie
inhibition of spindle elongation during meiosis
GOC:TermGenie
negative regulation of spindle elongation during meiosis
GOC:TermGenie
inhibition of meiotic spindle elongation
GOC:TermGenie
Any apoptotic process that is involved in blood vessel morphogenesis.
dph
2013-06-25T16:16:00Z
apoptotic cell death involved in patterning of blood vessels
apoptotic programmed cell death involved in patterning of blood vessels
programmed cell death by apoptosis involved in patterning of blood vessels
apoptosis involved in patterning of blood vessels
apoptotic program involved in patterning of blood vessels
type I programmed cell death involved in patterning of blood vessels
biological_process
signaling (initiator) caspase activity involved in patterning of blood vessels
GO:1902262
apoptotic process involved in blood vessel morphogenesis
Any apoptotic process that is involved in blood vessel morphogenesis.
GOC:TermGenie
GOC:dph
GOC:mtg_apoptosis
PMID:16163358
apoptotic cell death involved in patterning of blood vessels
GOC:TermGenie
apoptotic programmed cell death involved in patterning of blood vessels
GOC:TermGenie
programmed cell death by apoptosis involved in patterning of blood vessels
GOC:TermGenie
apoptosis involved in patterning of blood vessels
GOC:TermGenie
apoptotic program involved in patterning of blood vessels
GOC:TermGenie
type I programmed cell death involved in patterning of blood vessels
GOC:TermGenie
signaling (initiator) caspase activity involved in patterning of blood vessels
GOC:TermGenie
Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.
sart
2013-07-29T15:03:16Z
regulation of apoptosis involved in morphogenesis
biological_process
regulation of apoptosis involved in development
regulation of morphogenetic apoptosis
GO:1902337
regulation of apoptotic process involved in morphogenesis
Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.
GOC:TermGenie
GOC:sart
PMID:12202035
regulation of apoptosis involved in morphogenesis
GOC:TermGenie
regulation of apoptosis involved in development
GOC:TermGenie
regulation of morphogenetic apoptosis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.
sart
2013-07-29T15:03:25Z
down regulation of apoptotic process involved in morphogenesis
down-regulation of apoptotic process involved in morphogenesis
downregulation of apoptotic process involved in morphogenesis
down regulation of apoptosis involved in morphogenesis
down-regulation of apoptosis involved in morphogenesis
downregulation of apoptosis involved in morphogenesis
inhibition of apoptosis involved in morphogenesis
inhibition of apoptotic process involved in morphogenesis
negative regulation of apoptosis involved in morphogenesis
biological_process
down regulation of apoptosis involved in development
down regulation of morphogenetic apoptosis
down-regulation of apoptosis involved in development
down-regulation of morphogenetic apoptosis
downregulation of apoptosis involved in development
downregulation of morphogenetic apoptosis
inhibition of apoptosis involved in development
inhibition of morphogenetic apoptosis
negative regulation of apoptosis involved in development
negative regulation of morphogenetic apoptosis
GO:1902338
negative regulation of apoptotic process involved in morphogenesis
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.
GOC:TermGenie
GOC:sart
PMID:12202035
down regulation of apoptotic process involved in morphogenesis
GOC:TermGenie
down-regulation of apoptotic process involved in morphogenesis
GOC:TermGenie
downregulation of apoptotic process involved in morphogenesis
GOC:TermGenie
down regulation of apoptosis involved in morphogenesis
GOC:TermGenie
down-regulation of apoptosis involved in morphogenesis
GOC:TermGenie
downregulation of apoptosis involved in morphogenesis
GOC:TermGenie
inhibition of apoptosis involved in morphogenesis
GOC:TermGenie
inhibition of apoptotic process involved in morphogenesis
GOC:TermGenie
negative regulation of apoptosis involved in morphogenesis
GOC:TermGenie
down regulation of apoptosis involved in development
GOC:TermGenie
down regulation of morphogenetic apoptosis
GOC:TermGenie
down-regulation of apoptosis involved in development
GOC:TermGenie
down-regulation of morphogenetic apoptosis
GOC:TermGenie
downregulation of apoptosis involved in development
GOC:TermGenie
downregulation of morphogenetic apoptosis
GOC:TermGenie
inhibition of apoptosis involved in development
GOC:TermGenie
inhibition of morphogenetic apoptosis
GOC:TermGenie
negative regulation of apoptosis involved in development
GOC:TermGenie
negative regulation of morphogenetic apoptosis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.
sart
2013-07-29T15:03:33Z
up regulation of apoptotic process involved in morphogenesis
up-regulation of apoptotic process involved in morphogenesis
upregulation of apoptotic process involved in morphogenesis
activation of apoptosis involved in morphogenesis
activation of apoptotic process involved in morphogenesis
positive regulation of apoptosis involved in morphogenesis
up regulation of apoptosis involved in morphogenesis
up-regulation of apoptosis involved in morphogenesis
upregulation of apoptosis involved in morphogenesis
biological_process
activation of apoptosis involved in development
activation of morphogenetic apoptosis
positive regulation of apoptosis involved in development
positive regulation of morphogenetic apoptosis
up regulation of apoptosis involved in development
up regulation of morphogenetic apoptosis
up-regulation of apoptosis involved in development
up-regulation of morphogenetic apoptosis
upregulation of apoptosis involved in development
upregulation of morphogenetic apoptosis
GO:1902339
positive regulation of apoptotic process involved in morphogenesis
Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.
GOC:TermGenie
GOC:sart
PMID:12202035
up regulation of apoptotic process involved in morphogenesis
GOC:TermGenie
up-regulation of apoptotic process involved in morphogenesis
GOC:TermGenie
upregulation of apoptotic process involved in morphogenesis
GOC:TermGenie
activation of apoptosis involved in morphogenesis
GOC:TermGenie
activation of apoptotic process involved in morphogenesis
GOC:TermGenie
positive regulation of apoptosis involved in morphogenesis
GOC:TermGenie
up regulation of apoptosis involved in morphogenesis
GOC:TermGenie
up-regulation of apoptosis involved in morphogenesis
GOC:TermGenie
upregulation of apoptosis involved in morphogenesis
GOC:TermGenie
activation of apoptosis involved in development
GOC:TermGenie
activation of morphogenetic apoptosis
GOC:TermGenie
positive regulation of apoptosis involved in development
GOC:TermGenie
positive regulation of morphogenetic apoptosis
GOC:TermGenie
up regulation of apoptosis involved in development
GOC:TermGenie
up regulation of morphogenetic apoptosis
GOC:TermGenie
up-regulation of apoptosis involved in development
GOC:TermGenie
up-regulation of morphogenetic apoptosis
GOC:TermGenie
upregulation of apoptosis involved in development
GOC:TermGenie
upregulation of morphogenetic apoptosis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.
dgf
2013-07-29T20:54:14Z
down regulation of chromosome condensation
down regulation of eukaryotic chromosome condensation
down regulation of nuclear chromosome condensation
down-regulation of chromosome condensation
down-regulation of eukaryotic chromosome condensation
down-regulation of nuclear chromosome condensation
downregulation of chromosome condensation
downregulation of eukaryotic chromosome condensation
downregulation of nuclear chromosome condensation
negative regulation of eukaryotic chromosome condensation
negative regulation of nuclear chromosome condensation
inhibition of chromosome condensation
inhibition of eukaryotic chromosome condensation
inhibition of nuclear chromosome condensation
biological_process
GO:1902340
negative regulation of chromosome condensation
Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.
GOC:TermGenie
PMID:23219725
down regulation of chromosome condensation
GOC:TermGenie
down regulation of eukaryotic chromosome condensation
GOC:TermGenie
down regulation of nuclear chromosome condensation
GOC:TermGenie
down-regulation of chromosome condensation
GOC:TermGenie
down-regulation of eukaryotic chromosome condensation
GOC:TermGenie
down-regulation of nuclear chromosome condensation
GOC:TermGenie
downregulation of chromosome condensation
GOC:TermGenie
downregulation of eukaryotic chromosome condensation
GOC:TermGenie
downregulation of nuclear chromosome condensation
GOC:TermGenie
negative regulation of eukaryotic chromosome condensation
GOC:TermGenie
negative regulation of nuclear chromosome condensation
GOC:TermGenie
inhibition of chromosome condensation
GOC:TermGenie
inhibition of eukaryotic chromosome condensation
GOC:TermGenie
inhibition of nuclear chromosome condensation
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
dw
2013-12-02T09:34:08Z
biological_process
GO:1902518
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to cyclophosphamide
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
dw
2013-12-02T09:44:04Z
biological_process
response to docetaxel
GO:1902519
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to docetaxel trihydrate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
dw
2013-12-02T09:44:13Z
biological_process
GO:1902520
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to doxorubicin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
dw
2013-12-02T09:44:22Z
biological_process
GO:1902521
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to etoposide
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
dw
2013-12-02T09:44:31Z
biological_process
response to epirubicin
GO:1902522
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to 4'-epidoxorubicin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that modulates the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:32:52Z
GO:0010627
regulation of intracellular signaling cascade
regulation of intracellular signaling chain
regulation of intracellular protein kinase cascade
regulation of intracellular signal transduction pathway
regulation of signal transmission via intracellular cascade
biological_process
regulation of intracellular signaling pathway
regulation of signal transduction via intracellular signaling cascade
GO:1902531
regulation of intracellular signal transduction
Any process that modulates the frequency, rate or extent of intracellular signal transduction.
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
regulation of intracellular signaling cascade
GOC:TermGenie
regulation of intracellular signaling chain
GOC:TermGenie
regulation of intracellular signal transduction pathway
GOC:TermGenie
regulation of signal transmission via intracellular cascade
GOC:TermGenie
regulation of intracellular signaling pathway
GOC:TermGenie
regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:33:01Z
GO:0010741
down regulation of intracellular signal transduction
down regulation of intracellular signaling chain
down-regulation of intracellular signal transduction
down-regulation of intracellular signaling chain
downregulation of intracellular signal transduction
downregulation of intracellular signaling chain
negative regulation of intracellular protein kinase cascade
negative regulation of intracellular signaling cascade
negative regulation of intracellular signaling chain
down regulation of intracellular signal transduction pathway
down regulation of intracellular signaling cascade
down regulation of signal transmission via intracellular cascade
down-regulation of intracellular signal transduction pathway
downregulation of intracellular signal transduction pathway
downregulation of intracellular signaling cascade
downregulation of signal transmission via intracellular cascade
inhibition of intracellular signal transduction
inhibition of intracellular signal transduction pathway
inhibition of intracellular signaling cascade
inhibition of intracellular signaling chain
inhibition of signal transmission via intracellular cascade
negative regulation of intracellular signal transduction pathway
negative regulation of signal transmission via intracellular cascade
biological_process
down regulation of intracellular signaling pathway
down regulation of signal transduction via intracellular signaling cascade
down-regulation of intracellular signaling cascade
down-regulation of intracellular signaling pathway
down-regulation of signal transduction via intracellular signaling cascade
down-regulation of signal transmission via intracellular cascade
downregulation of intracellular signaling pathway
downregulation of signal transduction via intracellular signaling cascade
inhibition of intracellular signaling pathway
inhibition of signal transduction via intracellular signaling cascade
negative regulation of intracellular signaling pathway
negative regulation of signal transduction via intracellular signaling cascade
GO:1902532
negative regulation of intracellular signal transduction
Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
down regulation of intracellular signal transduction
GOC:TermGenie
down regulation of intracellular signaling chain
GOC:TermGenie
down-regulation of intracellular signal transduction
GOC:TermGenie
down-regulation of intracellular signaling chain
GOC:TermGenie
downregulation of intracellular signal transduction
GOC:TermGenie
downregulation of intracellular signaling chain
GOC:TermGenie
negative regulation of intracellular signaling cascade
GOC:TermGenie
negative regulation of intracellular signaling chain
GOC:TermGenie
down regulation of intracellular signal transduction pathway
GOC:TermGenie
down regulation of intracellular signaling cascade
GOC:TermGenie
down regulation of signal transmission via intracellular cascade
GOC:TermGenie
down-regulation of intracellular signal transduction pathway
GOC:TermGenie
downregulation of intracellular signal transduction pathway
GOC:TermGenie
downregulation of intracellular signaling cascade
GOC:TermGenie
downregulation of signal transmission via intracellular cascade
GOC:TermGenie
inhibition of intracellular signal transduction
GOC:TermGenie
inhibition of intracellular signal transduction pathway
GOC:TermGenie
inhibition of intracellular signaling cascade
GOC:TermGenie
inhibition of intracellular signaling chain
GOC:TermGenie
inhibition of signal transmission via intracellular cascade
GOC:TermGenie
negative regulation of intracellular signal transduction pathway
GOC:TermGenie
negative regulation of signal transmission via intracellular cascade
GOC:TermGenie
down regulation of intracellular signaling pathway
GOC:TermGenie
down regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
down-regulation of intracellular signaling cascade
GOC:TermGenie
down-regulation of intracellular signaling pathway
GOC:TermGenie
down-regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
down-regulation of signal transmission via intracellular cascade
GOC:TermGenie
downregulation of intracellular signaling pathway
GOC:TermGenie
downregulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
inhibition of intracellular signaling pathway
GOC:TermGenie
inhibition of signal transduction via intracellular signaling cascade
GOC:TermGenie
negative regulation of intracellular signaling pathway
GOC:TermGenie
negative regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:33:10Z
GO:0010740
positive regulation of intracellular signaling chain
up regulation of intracellular signal transduction
up regulation of intracellular signaling chain
up-regulation of intracellular signal transduction
up-regulation of intracellular signaling chain
upregulation of intracellular signal transduction
upregulation of intracellular signaling chain
activation of intracellular signal transduction
activation of intracellular signal transduction pathway
activation of intracellular signaling cascade
activation of intracellular signaling chain
activation of signal transmission via intracellular cascade
positive regulation of intracellular protein kinase cascade
positive regulation of intracellular signal transduction pathway
positive regulation of signal transmission via intracellular cascade
up regulation of intracellular signal transduction pathway
up regulation of signal transmission via intracellular cascade
up-regulation of intracellular signal transduction pathway
up-regulation of signal transmission via intracellular cascade
upregulation of intracellular signal transduction pathway
upregulation of signal transmission via intracellular cascade
biological_process
activation of intracellular signaling pathway
activation of signal transduction via intracellular signaling cascade
positive regulation of intracellular signaling cascade
positive regulation of intracellular signaling pathway
positive regulation of signal transduction via intracellular signaling cascade
up regulation of intracellular signaling cascade
up regulation of intracellular signaling pathway
up regulation of signal transduction via intracellular signaling cascade
up-regulation of intracellular signaling cascade
up-regulation of intracellular signaling pathway
up-regulation of signal transduction via intracellular signaling cascade
upregulation of intracellular signaling cascade
upregulation of intracellular signaling pathway
upregulation of signal transduction via intracellular signaling cascade
GO:1902533
positive regulation of intracellular signal transduction
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
GOC:BHF
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
positive regulation of intracellular signaling chain
GOC:TermGenie
up regulation of intracellular signal transduction
GOC:TermGenie
up regulation of intracellular signaling chain
GOC:TermGenie
up-regulation of intracellular signal transduction
GOC:TermGenie
up-regulation of intracellular signaling chain
GOC:TermGenie
upregulation of intracellular signal transduction
GOC:TermGenie
upregulation of intracellular signaling chain
GOC:TermGenie
activation of intracellular signal transduction
GOC:TermGenie
activation of intracellular signal transduction pathway
GOC:TermGenie
activation of intracellular signaling cascade
GOC:TermGenie
activation of intracellular signaling chain
GOC:TermGenie
activation of signal transmission via intracellular cascade
GOC:TermGenie
positive regulation of intracellular signal transduction pathway
GOC:TermGenie
positive regulation of signal transmission via intracellular cascade
GOC:TermGenie
up regulation of intracellular signal transduction pathway
GOC:TermGenie
up regulation of signal transmission via intracellular cascade
GOC:TermGenie
up-regulation of intracellular signal transduction pathway
GOC:TermGenie
up-regulation of signal transmission via intracellular cascade
GOC:TermGenie
upregulation of intracellular signal transduction pathway
GOC:TermGenie
upregulation of signal transmission via intracellular cascade
GOC:TermGenie
activation of intracellular signaling pathway
GOC:TermGenie
activation of signal transduction via intracellular signaling cascade
GOC:TermGenie
positive regulation of intracellular signaling cascade
GOC:TermGenie
positive regulation of intracellular signaling pathway
GOC:TermGenie
positive regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
up regulation of intracellular signaling cascade
GOC:TermGenie
up regulation of intracellular signaling pathway
GOC:TermGenie
up regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
up-regulation of intracellular signaling cascade
GOC:TermGenie
up-regulation of intracellular signaling pathway
GOC:TermGenie
up-regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
upregulation of intracellular signaling cascade
GOC:TermGenie
upregulation of intracellular signaling pathway
GOC:TermGenie
upregulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
A localization which involves another organism.
jl
2013-12-18T13:51:13Z
multi organism localization
biological_process
GO:1902579
multi-organism localization
A localization which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism localization
GOC:TermGenie
A cellular localization which involves another organism.
jl
2013-12-18T14:04:41Z
multi organism cellular localization
biological_process
GO:1902581
multi-organism cellular localization
A cellular localization which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism cellular localization
GOC:TermGenie
OBSOLETE. An intracellular transport which involves another organism.
jl
2013-12-18T14:04:58Z
multi organism intracellular transport
biological_process
GO:1902583
This term was obsoleted because there is no evidence that this process exists.
obsolete multi-organism intracellular transport
true
OBSOLETE. An intracellular transport which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism intracellular transport
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of response to water deprivation.
tb
2013-12-19T00:31:58Z
positive regulation of response to dehydration
positive regulation of response to drought
positive regulation of response to thirst
up regulation of response to dehydration
up regulation of response to drought
up regulation of response to thirst
up regulation of response to water deprivation
up-regulation of response to dehydration
up-regulation of response to drought
up-regulation of response to thirst
up-regulation of response to water deprivation
upregulation of response to dehydration
upregulation of response to drought
upregulation of response to thirst
upregulation of response to water deprivation
activation of response to dehydration
activation of response to drought
activation of response to thirst
activation of response to water deprivation
biological_process
activation of drought tolerance
positive regulation of drought tolerance
up regulation of drought tolerance
up-regulation of drought tolerance
upregulation of drought tolerance
GO:1902584
positive regulation of response to water deprivation
Any process that activates or increases the frequency, rate or extent of response to water deprivation.
GOC:TermGenie
GO_REF:0000058
PMID:24198318
positive regulation of response to dehydration
GOC:TermGenie
positive regulation of response to drought
GOC:TermGenie
positive regulation of response to thirst
GOC:TermGenie
up regulation of response to dehydration
GOC:TermGenie
up regulation of response to drought
GOC:TermGenie
up regulation of response to thirst
GOC:TermGenie
up regulation of response to water deprivation
GOC:TermGenie
up-regulation of response to dehydration
GOC:TermGenie
up-regulation of response to drought
GOC:TermGenie
up-regulation of response to thirst
GOC:TermGenie
up-regulation of response to water deprivation
GOC:TermGenie
upregulation of response to dehydration
GOC:TermGenie
upregulation of response to drought
GOC:TermGenie
upregulation of response to thirst
GOC:TermGenie
upregulation of response to water deprivation
GOC:TermGenie
activation of response to dehydration
GOC:TermGenie
activation of response to drought
GOC:TermGenie
activation of response to thirst
GOC:TermGenie
activation of response to water deprivation
GOC:TermGenie
activation of drought tolerance
GOC:TermGenie
positive regulation of drought tolerance
GOC:TermGenie
up regulation of drought tolerance
GOC:TermGenie
up-regulation of drought tolerance
GOC:TermGenie
upregulation of drought tolerance
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
jl
2014-02-05T16:32:01Z
down regulation of RNA anabolism
down regulation of RNA biosynthesis
down regulation of RNA biosynthetic process
down regulation of RNA formation
down regulation of RNA synthesis
down-regulation of RNA anabolism
down-regulation of RNA biosynthesis
down-regulation of RNA biosynthetic process
down-regulation of RNA formation
down-regulation of RNA synthesis
downregulation of RNA anabolism
downregulation of RNA biosynthesis
downregulation of RNA biosynthetic process
downregulation of RNA formation
downregulation of RNA synthesis
negative regulation of RNA anabolism
negative regulation of RNA biosynthesis
negative regulation of RNA formation
negative regulation of RNA synthesis
inhibition of RNA anabolism
inhibition of RNA biosynthesis
inhibition of RNA biosynthetic process
inhibition of RNA formation
inhibition of RNA synthesis
biological_process
GO:1902679
negative regulation of RNA biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
GO:jl
GOC:TermGenie
GO_REF:0000058
down regulation of RNA anabolism
GOC:TermGenie
down regulation of RNA biosynthesis
GOC:TermGenie
down regulation of RNA biosynthetic process
GOC:TermGenie
down regulation of RNA formation
GOC:TermGenie
down regulation of RNA synthesis
GOC:TermGenie
down-regulation of RNA anabolism
GOC:TermGenie
down-regulation of RNA biosynthesis
GOC:TermGenie
down-regulation of RNA biosynthetic process
GOC:TermGenie
down-regulation of RNA formation
GOC:TermGenie
down-regulation of RNA synthesis
GOC:TermGenie
downregulation of RNA anabolism
GOC:TermGenie
downregulation of RNA biosynthesis
GOC:TermGenie
downregulation of RNA biosynthetic process
GOC:TermGenie
downregulation of RNA formation
GOC:TermGenie
downregulation of RNA synthesis
GOC:TermGenie
negative regulation of RNA anabolism
GOC:TermGenie
negative regulation of RNA biosynthesis
GOC:TermGenie
negative regulation of RNA formation
GOC:TermGenie
negative regulation of RNA synthesis
GOC:TermGenie
inhibition of RNA anabolism
GOC:TermGenie
inhibition of RNA biosynthesis
GOC:TermGenie
inhibition of RNA biosynthetic process
GOC:TermGenie
inhibition of RNA formation
GOC:TermGenie
inhibition of RNA synthesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
jl
2014-02-05T16:32:10Z
positive regulation of RNA anabolism
positive regulation of RNA biosynthesis
positive regulation of RNA formation
positive regulation of RNA synthesis
up regulation of RNA anabolism
up regulation of RNA biosynthesis
up regulation of RNA biosynthetic process
up regulation of RNA formation
up regulation of RNA synthesis
up-regulation of RNA anabolism
up-regulation of RNA biosynthesis
up-regulation of RNA biosynthetic process
up-regulation of RNA formation
up-regulation of RNA synthesis
upregulation of RNA anabolism
upregulation of RNA biosynthesis
upregulation of RNA biosynthetic process
upregulation of RNA formation
upregulation of RNA synthesis
activation of RNA anabolism
activation of RNA biosynthesis
activation of RNA biosynthetic process
activation of RNA formation
activation of RNA synthesis
biological_process
GO:1902680
positive regulation of RNA biosynthetic process
Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
GO:jl
GOC:TermGenie
GO_REF:0000058
positive regulation of RNA anabolism
GOC:TermGenie
positive regulation of RNA biosynthesis
GOC:TermGenie
positive regulation of RNA formation
GOC:TermGenie
positive regulation of RNA synthesis
GOC:TermGenie
up regulation of RNA anabolism
GOC:TermGenie
up regulation of RNA biosynthesis
GOC:TermGenie
up regulation of RNA biosynthetic process
GOC:TermGenie
up regulation of RNA formation
GOC:TermGenie
up regulation of RNA synthesis
GOC:TermGenie
up-regulation of RNA anabolism
GOC:TermGenie
up-regulation of RNA biosynthesis
GOC:TermGenie
up-regulation of RNA biosynthetic process
GOC:TermGenie
up-regulation of RNA formation
GOC:TermGenie
up-regulation of RNA synthesis
GOC:TermGenie
upregulation of RNA anabolism
GOC:TermGenie
upregulation of RNA biosynthesis
GOC:TermGenie
upregulation of RNA biosynthetic process
GOC:TermGenie
upregulation of RNA formation
GOC:TermGenie
upregulation of RNA synthesis
GOC:TermGenie
activation of RNA anabolism
GOC:TermGenie
activation of RNA biosynthesis
GOC:TermGenie
activation of RNA biosynthetic process
GOC:TermGenie
activation of RNA formation
GOC:TermGenie
activation of RNA synthesis
GOC:TermGenie
Any apoptotic process that is involved in anatomical structure development.
pr
2014-02-28T13:09:43Z
apoptotic cell death involved in anatomical structure development
apoptotic cell death involved in development of an anatomical structure
apoptotic process involved in anatomical structure development
apoptotic process involved in development of an anatomical structure
apoptotic programmed cell death involved in anatomical structure development
apoptotic programmed cell death involved in development of an anatomical structure
programmed cell death by apoptosis involved in anatomical structure development
programmed cell death by apoptosis involved in development of an anatomical structure
activation of apoptosis involved in anatomical structure development
activation of apoptosis involved in development of an anatomical structure
apoptosis involved in anatomical structure development
apoptosis involved in development of an anatomical structure
apoptosis signaling involved in anatomical structure development
apoptosis signaling involved in development of an anatomical structure
apoptotic program involved in anatomical structure development
apoptotic program involved in development of an anatomical structure
type I programmed cell death involved in anatomical structure development
type I programmed cell death involved in development of an anatomical structure
biological_process
apoptosis activator activity involved in anatomical structure development
apoptosis activator activity involved in development of an anatomical structure
commitment to apoptosis involved in anatomical structure development
commitment to apoptosis involved in development of an anatomical structure
induction of apoptosis by p53 involved in anatomical structure development
induction of apoptosis by p53 involved in development of an anatomical structure
induction of apoptosis involved in anatomical structure development
induction of apoptosis involved in development of an anatomical structure
signaling (initiator) caspase activity involved in anatomical structure development
signaling (initiator) caspase activity involved in development of an anatomical structure
GO:1902742
apoptotic process involved in development
Any apoptotic process that is involved in anatomical structure development.
GOC:TermGenie
GOC:mtg_apoptosis
GOC:pg
GO_REF:0000060
apoptotic cell death involved in anatomical structure development
GOC:TermGenie
apoptotic cell death involved in development of an anatomical structure
GOC:TermGenie
apoptotic process involved in development of an anatomical structure
GOC:TermGenie
apoptotic programmed cell death involved in anatomical structure development
GOC:TermGenie
apoptotic programmed cell death involved in development of an anatomical structure
GOC:TermGenie
programmed cell death by apoptosis involved in anatomical structure development
GOC:TermGenie
programmed cell death by apoptosis involved in development of an anatomical structure
GOC:TermGenie
activation of apoptosis involved in anatomical structure development
GOC:TermGenie
activation of apoptosis involved in development of an anatomical structure
GOC:TermGenie
apoptosis involved in anatomical structure development
GOC:TermGenie
apoptosis involved in development of an anatomical structure
GOC:TermGenie
apoptosis signaling involved in anatomical structure development
GOC:TermGenie
apoptosis signaling involved in development of an anatomical structure
GOC:TermGenie
apoptotic program involved in anatomical structure development
GOC:TermGenie
apoptotic program involved in development of an anatomical structure
GOC:TermGenie
type I programmed cell death involved in anatomical structure development
GOC:TermGenie
type I programmed cell death involved in development of an anatomical structure
GOC:TermGenie
apoptosis activator activity involved in anatomical structure development
GOC:TermGenie
apoptosis activator activity involved in development of an anatomical structure
GOC:TermGenie
commitment to apoptosis involved in anatomical structure development
GOC:TermGenie
commitment to apoptosis involved in development of an anatomical structure
GOC:TermGenie
induction of apoptosis by p53 involved in anatomical structure development
GOC:TermGenie
induction of apoptosis by p53 involved in development of an anatomical structure
GOC:TermGenie
induction of apoptosis involved in anatomical structure development
GOC:TermGenie
induction of apoptosis involved in development of an anatomical structure
GOC:TermGenie
signaling (initiator) caspase activity involved in anatomical structure development
GOC:TermGenie
signaling (initiator) caspase activity involved in development of an anatomical structure
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.
vw
2014-04-02T08:43:28Z
down regulation of mitotic spindle elongation
down regulation of spindle elongation during mitosis
down-regulation of mitotic spindle elongation
down-regulation of spindle elongation during mitosis
downregulation of mitotic spindle elongation
downregulation of spindle elongation during mitosis
negative regulation of spindle elongation during mitosis
inhibition of mitotic spindle elongation
inhibition of spindle elongation during mitosis
biological_process
GO:1902845
negative regulation of mitotic spindle elongation
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.
GOC:TermGenie
GO_REF:0000058
PMID:23087209
down regulation of mitotic spindle elongation
GOC:TermGenie
down regulation of spindle elongation during mitosis
GOC:TermGenie
down-regulation of mitotic spindle elongation
GOC:TermGenie
down-regulation of spindle elongation during mitosis
GOC:TermGenie
downregulation of mitotic spindle elongation
GOC:TermGenie
downregulation of spindle elongation during mitosis
GOC:TermGenie
negative regulation of spindle elongation during mitosis
GOC:TermGenie
inhibition of mitotic spindle elongation
GOC:TermGenie
inhibition of spindle elongation during mitosis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.
vw
2014-04-02T08:43:34Z
positive regulation of spindle elongation during mitosis
up regulation of mitotic spindle elongation
up regulation of spindle elongation during mitosis
up-regulation of mitotic spindle elongation
up-regulation of spindle elongation during mitosis
upregulation of mitotic spindle elongation
upregulation of spindle elongation during mitosis
activation of mitotic spindle elongation
activation of spindle elongation during mitosis
biological_process
GO:1902846
positive regulation of mitotic spindle elongation
Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.
GOC:TermGenie
GO_REF:0000058
PMID:23087209
positive regulation of spindle elongation during mitosis
GOC:TermGenie
up regulation of mitotic spindle elongation
GOC:TermGenie
up regulation of spindle elongation during mitosis
GOC:TermGenie
up-regulation of mitotic spindle elongation
GOC:TermGenie
up-regulation of spindle elongation during mitosis
GOC:TermGenie
upregulation of mitotic spindle elongation
GOC:TermGenie
upregulation of spindle elongation during mitosis
GOC:TermGenie
activation of mitotic spindle elongation
GOC:TermGenie
activation of spindle elongation during mitosis
GOC:TermGenie
Any microtubule cytoskeleton organization that is involved in mitosis.
vw
2014-04-02T14:19:38Z
microtubule cytoskeleton organisation involved in mitosis
microtubule dynamics involved in mitosis
biological_process
microtubule cytoskeleton organization and biogenesis involved in mitosis
GO:1902850
microtubule cytoskeleton organization involved in mitosis
Any microtubule cytoskeleton organization that is involved in mitosis.
GOC:TermGenie
GO_REF:0000060
PMID:18799626
microtubule cytoskeleton organisation involved in mitosis
GOC:TermGenie
microtubule dynamics involved in mitosis
GOC:TermGenie
microtubule cytoskeleton organization and biogenesis involved in mitosis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.
als
2014-04-15T10:37:40Z
down regulation of autophagic vacuole assembly
down regulation of autophagosome biosynthesis
down regulation of autophagosome formation
down-regulation of autophagic vacuole assembly
down-regulation of autophagosome biosynthesis
down-regulation of autophagosome formation
downregulation of autophagic vacuole assembly
downregulation of autophagosome biosynthesis
downregulation of autophagosome formation
negative regulation of autophagic vacuole assembly
negative regulation of autophagosome biosynthesis
negative regulation of autophagosome formation
down regulation of PAS formation
down-regulation of PAS formation
downregulation of PAS formation
inhibition of PAS formation
inhibition of autophagic vacuole assembly
inhibition of autophagosome biosynthesis
inhibition of autophagosome formation
negative regulation of PAS formation
biological_process
down regulation of autophagic vacuole formation
down-regulation of autophagic vacuole formation
downregulation of autophagic vacuole formation
inhibition of autophagic vacuole formation
negative regulation of autophagic vacuole formation
GO:1902902
negative regulation of autophagosome assembly
Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.
GOC:TermGenie
GOC:als
GOC:autophagy
GO_REF:0000058
PMID:21975012
down regulation of autophagic vacuole assembly
GOC:TermGenie
down regulation of autophagosome biosynthesis
GOC:TermGenie
down regulation of autophagosome formation
GOC:TermGenie
down-regulation of autophagic vacuole assembly
GOC:TermGenie
down-regulation of autophagosome biosynthesis
GOC:TermGenie
down-regulation of autophagosome formation
GOC:TermGenie
downregulation of autophagic vacuole assembly
GOC:TermGenie
downregulation of autophagosome biosynthesis
GOC:TermGenie
downregulation of autophagosome formation
GOC:TermGenie
negative regulation of autophagic vacuole assembly
GOC:autophagy
negative regulation of autophagosome biosynthesis
GOC:TermGenie
negative regulation of autophagosome formation
GOC:TermGenie
down regulation of PAS formation
GOC:TermGenie
down-regulation of PAS formation
GOC:TermGenie
downregulation of PAS formation
GOC:TermGenie
inhibition of PAS formation
GOC:TermGenie
inhibition of autophagic vacuole assembly
GOC:TermGenie
inhibition of autophagosome biosynthesis
GOC:TermGenie
inhibition of autophagosome formation
GOC:TermGenie
negative regulation of PAS formation
GOC:TermGenie
down regulation of autophagic vacuole formation
GOC:TermGenie
down-regulation of autophagic vacuole formation
GOC:TermGenie
downregulation of autophagic vacuole formation
GOC:TermGenie
inhibition of autophagic vacuole formation
GOC:TermGenie
negative regulation of autophagic vacuole formation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.
rl
2014-05-14T18:44:19Z
regulation of glycoprotein metabolism
biological_process
GO:1903018
human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
regulation of glycoprotein metabolic process
Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23544079
regulation of glycoprotein metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
rl
2014-05-14T18:44:25Z
down regulation of glycoprotein metabolic process
down regulation of glycoprotein metabolism
down-regulation of glycoprotein metabolic process
down-regulation of glycoprotein metabolism
downregulation of glycoprotein metabolic process
downregulation of glycoprotein metabolism
negative regulation of glycoprotein metabolism
inhibition of glycoprotein metabolic process
inhibition of glycoprotein metabolism
biological_process
GO:1903019
human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
negative regulation of glycoprotein metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23544079
down regulation of glycoprotein metabolic process
GOC:TermGenie
down regulation of glycoprotein metabolism
GOC:TermGenie
down-regulation of glycoprotein metabolic process
GOC:TermGenie
down-regulation of glycoprotein metabolism
GOC:TermGenie
downregulation of glycoprotein metabolic process
GOC:TermGenie
downregulation of glycoprotein metabolism
GOC:TermGenie
negative regulation of glycoprotein metabolism
GOC:TermGenie
inhibition of glycoprotein metabolic process
GOC:TermGenie
inhibition of glycoprotein metabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.
rl
2014-05-14T18:44:31Z
positive regulation of glycoprotein metabolism
up regulation of glycoprotein metabolic process
up regulation of glycoprotein metabolism
up-regulation of glycoprotein metabolic process
up-regulation of glycoprotein metabolism
upregulation of glycoprotein metabolic process
upregulation of glycoprotein metabolism
activation of glycoprotein metabolic process
activation of glycoprotein metabolism
biological_process
GO:1903020
human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
positive regulation of glycoprotein metabolic process
Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23544079
positive regulation of glycoprotein metabolism
GOC:TermGenie
up regulation of glycoprotein metabolic process
GOC:TermGenie
up regulation of glycoprotein metabolism
GOC:TermGenie
up-regulation of glycoprotein metabolic process
GOC:TermGenie
up-regulation of glycoprotein metabolism
GOC:TermGenie
upregulation of glycoprotein metabolic process
GOC:TermGenie
upregulation of glycoprotein metabolism
GOC:TermGenie
activation of glycoprotein metabolic process
GOC:TermGenie
activation of glycoprotein metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of response to wounding.
kmv
2014-05-18T01:28:46Z
regulation of physiological response to wounding
biological_process
GO:1903034
regulation of response to wounding
Any process that modulates the frequency, rate or extent of response to wounding.
GOC:TermGenie
GOC:kmv
GO_REF:0000058
pmid:19164535
regulation of physiological response to wounding
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.
kmv
2014-05-18T01:28:52Z
down regulation of physiological response to wounding
down regulation of response to wounding
down-regulation of physiological response to wounding
down-regulation of response to wounding
downregulation of physiological response to wounding
downregulation of response to wounding
negative regulation of physiological response to wounding
inhibition of physiological response to wounding
inhibition of response to wounding
biological_process
GO:1903035
negative regulation of response to wounding
Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.
GOC:TermGenie
GOC:kmv
GO_REF:0000058
pmid:19164535
down regulation of physiological response to wounding
GOC:TermGenie
down regulation of response to wounding
GOC:TermGenie
down-regulation of physiological response to wounding
GOC:TermGenie
down-regulation of response to wounding
GOC:TermGenie
downregulation of physiological response to wounding
GOC:TermGenie
downregulation of response to wounding
GOC:TermGenie
negative regulation of physiological response to wounding
GOC:TermGenie
inhibition of physiological response to wounding
GOC:TermGenie
inhibition of response to wounding
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of response to wounding.
kmv
2014-05-18T01:28:58Z
positive regulation of physiological response to wounding
up regulation of physiological response to wounding
up regulation of response to wounding
up-regulation of physiological response to wounding
up-regulation of response to wounding
upregulation of physiological response to wounding
upregulation of response to wounding
activation of physiological response to wounding
activation of response to wounding
biological_process
GO:1903036
positive regulation of response to wounding
Any process that activates or increases the frequency, rate or extent of response to wounding.
GOC:TermGenie
GOC:kmv
GO_REF:0000058
pmid:19164535
positive regulation of physiological response to wounding
GOC:TermGenie
up regulation of physiological response to wounding
GOC:TermGenie
up regulation of response to wounding
GOC:TermGenie
up-regulation of physiological response to wounding
GOC:TermGenie
up-regulation of response to wounding
GOC:TermGenie
upregulation of physiological response to wounding
GOC:TermGenie
upregulation of response to wounding
GOC:TermGenie
activation of physiological response to wounding
GOC:TermGenie
activation of response to wounding
GOC:TermGenie
A process that is part of the meiotic cell cycle.
jl
2014-05-22T14:22:28Z
biological_process
GO:1903046
meiotic cell cycle process
A process that is part of the meiotic cell cycle.
GOC:TermGenie
GOC:mtg_cell_cycle
GO_REF:0000060
A process that is part of the mitotic cell cycle.
jl
2014-05-22T14:22:34Z
biological_process
GO:1903047
mitotic cell cycle process
A process that is part of the mitotic cell cycle.
GOC:TermGenie
GOC:mtg_cell_cycle
GO_REF:0000060
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:41Z
regulation of extracellular matrix organisation
biological_process
regulation of extracellular matrix organization and biogenesis
GO:1903053
regulation of extracellular matrix organization
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
regulation of extracellular matrix organisation
GOC:TermGenie
regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:47Z
down regulation of extracellular matrix organisation
down regulation of extracellular matrix organization
down-regulation of extracellular matrix organisation
down-regulation of extracellular matrix organization
downregulation of extracellular matrix organisation
downregulation of extracellular matrix organization
negative regulation of extracellular matrix organisation
inhibition of extracellular matrix organisation
inhibition of extracellular matrix organization
biological_process
down regulation of extracellular matrix organization and biogenesis
down-regulation of extracellular matrix organization and biogenesis
downregulation of extracellular matrix organization and biogenesis
inhibition of extracellular matrix organization and biogenesis
negative regulation of extracellular matrix organization and biogenesis
GO:1903054
negative regulation of extracellular matrix organization
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
down regulation of extracellular matrix organisation
GOC:TermGenie
down regulation of extracellular matrix organization
GOC:TermGenie
down-regulation of extracellular matrix organisation
GOC:TermGenie
down-regulation of extracellular matrix organization
GOC:TermGenie
downregulation of extracellular matrix organisation
GOC:TermGenie
downregulation of extracellular matrix organization
GOC:TermGenie
negative regulation of extracellular matrix organisation
GOC:TermGenie
inhibition of extracellular matrix organisation
GOC:TermGenie
inhibition of extracellular matrix organization
GOC:TermGenie
down regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
down-regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
downregulation of extracellular matrix organization and biogenesis
GOC:TermGenie
inhibition of extracellular matrix organization and biogenesis
GOC:TermGenie
negative regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:53Z
positive regulation of extracellular matrix organisation
up regulation of extracellular matrix organisation
up regulation of extracellular matrix organization
up-regulation of extracellular matrix organisation
up-regulation of extracellular matrix organization
upregulation of extracellular matrix organisation
upregulation of extracellular matrix organization
activation of extracellular matrix organisation
activation of extracellular matrix organization
biological_process
activation of extracellular matrix organization and biogenesis
positive regulation of extracellular matrix organization and biogenesis
up regulation of extracellular matrix organization and biogenesis
up-regulation of extracellular matrix organization and biogenesis
upregulation of extracellular matrix organization and biogenesis
GO:1903055
positive regulation of extracellular matrix organization
Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
positive regulation of extracellular matrix organisation
GOC:TermGenie
up regulation of extracellular matrix organisation
GOC:TermGenie
up regulation of extracellular matrix organization
GOC:TermGenie
up-regulation of extracellular matrix organisation
GOC:TermGenie
up-regulation of extracellular matrix organization
GOC:TermGenie
upregulation of extracellular matrix organisation
GOC:TermGenie
upregulation of extracellular matrix organization
GOC:TermGenie
activation of extracellular matrix organisation
GOC:TermGenie
activation of extracellular matrix organization
GOC:TermGenie
activation of extracellular matrix organization and biogenesis
GOC:TermGenie
positive regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
up regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
up-regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
upregulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.
al
2014-06-09T11:53:14Z
regulation of mitochondrial transcription
regulation of transcription from mitochondrial promoter
biological_process
GO:1903108
regulation of mitochondrial transcription
Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:21357609
regulation of mitochondrial transcription
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.
al
2014-06-09T11:53:20Z
positive regulation of mitochondrial transcription
positive regulation of transcription from mitochondrial promoter
up regulation of mitochondrial transcription
up regulation of transcription from mitochondrial promoter
up-regulation of mitochondrial transcription
up-regulation of transcription from mitochondrial promoter
upregulation of mitochondrial transcription
upregulation of transcription from mitochondrial promoter
activation of mitochondrial transcription
activation of transcription from mitochondrial promoter
biological_process
GO:1903109
positive regulation of mitochondrial transcription
Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:21357609
positive regulation of mitochondrial transcription
GOC:TermGenie
up regulation of mitochondrial transcription
GOC:TermGenie
up regulation of transcription from mitochondrial promoter
GOC:TermGenie
up-regulation of mitochondrial transcription
GOC:TermGenie
up-regulation of transcription from mitochondrial promoter
GOC:TermGenie
upregulation of mitochondrial transcription
GOC:TermGenie
upregulation of transcription from mitochondrial promoter
GOC:TermGenie
activation of mitochondrial transcription
GOC:TermGenie
activation of transcription from mitochondrial promoter
GOC:TermGenie
Any process that modulates the frequency, rate or extent of nucleus organization.
hjd
2014-08-20T19:36:16Z
regulation of nuclear organisation
regulation of nuclear organization
biological_process
regulation of nuclear morphology
regulation of nuclear organization and biogenesis
regulation of nucleus organization and biogenesis
GO:1903353
regulation of nucleus organization
Any process that modulates the frequency, rate or extent of nucleus organization.
GOC:TermGenie
GO_REF:0000058
PMID:16943282
regulation of nuclear organisation
GOC:TermGenie
regulation of nuclear organization
GOC:TermGenie
regulation of nuclear morphology
GOC:TermGenie
regulation of nuclear organization and biogenesis
GOC:TermGenie
regulation of nucleus organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.
al
2014-08-26T13:57:13Z
biological_process
GO:1903379
regulation of mitotic chromosome condensation
Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.
GOC:TermGenie
GO_REF:0000058
PMID:9490640
Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.
al
2014-08-26T13:57:29Z
up regulation of mitotic chromosome condensation
up-regulation of mitotic chromosome condensation
upregulation of mitotic chromosome condensation
activation of mitotic chromosome condensation
biological_process
GO:1903380
positive regulation of mitotic chromosome condensation
Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.
GOC:TermGenie
GO_REF:0000058
PMID:9490640
up regulation of mitotic chromosome condensation
GOC:TermGenie
up-regulation of mitotic chromosome condensation
GOC:TermGenie
upregulation of mitotic chromosome condensation
GOC:TermGenie
activation of mitotic chromosome condensation
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.
rl
2014-09-05T12:41:01Z
biological_process
cellular response to ouabain
GO:1903416
response to glycoside
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.
GOC:BHF
GOC:TermGenie
GOC:mtg_cardiac_conduct_nov11
GOC:rl
GO_REF:0000071
PMID:12027881
PMID:16243970
cellular response to ouabain
CHEBI:472805
Any process that modulates the frequency, rate or extent of cell maturation.
jl
2014-09-15T13:31:23Z
biological_process
regulation of functional differentiation
GO:1903429
regulation of cell maturation
Any process that modulates the frequency, rate or extent of cell maturation.
GOC:TermGenie
GO_REF:0000058
PMID:17459944
regulation of functional differentiation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.
jl
2014-09-15T13:31:32Z
down regulation of cell maturation
down-regulation of cell maturation
downregulation of cell maturation
inhibition of cell maturation
biological_process
down regulation of functional differentiation
down-regulation of functional differentiation
downregulation of functional differentiation
inhibition of functional differentiation
negative regulation of functional differentiation
GO:1903430
negative regulation of cell maturation
Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.
GOC:TermGenie
GO_REF:0000058
PMID:17459944
down regulation of cell maturation
GOC:TermGenie
down-regulation of cell maturation
GOC:TermGenie
downregulation of cell maturation
GOC:TermGenie
inhibition of cell maturation
GOC:TermGenie
down regulation of functional differentiation
GOC:TermGenie
down-regulation of functional differentiation
GOC:TermGenie
downregulation of functional differentiation
GOC:TermGenie
inhibition of functional differentiation
GOC:TermGenie
negative regulation of functional differentiation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cell maturation.
jl
2014-09-15T13:31:41Z
up regulation of cell maturation
up-regulation of cell maturation
upregulation of cell maturation
activation of cell maturation
biological_process
activation of functional differentiation
positive regulation of functional differentiation
up regulation of functional differentiation
up-regulation of functional differentiation
upregulation of functional differentiation
GO:1903431
positive regulation of cell maturation
Any process that activates or increases the frequency, rate or extent of cell maturation.
GOC:TermGenie
GO_REF:0000058
PMID:17459944
up regulation of cell maturation
GOC:TermGenie
up-regulation of cell maturation
GOC:TermGenie
upregulation of cell maturation
GOC:TermGenie
activation of cell maturation
GOC:TermGenie
activation of functional differentiation
GOC:TermGenie
positive regulation of functional differentiation
GOC:TermGenie
up regulation of functional differentiation
GOC:TermGenie
up-regulation of functional differentiation
GOC:TermGenie
upregulation of functional differentiation
GOC:TermGenie
Any RNA interference that is involved in olfactory learning.
kmv
2014-09-22T13:50:09Z
RNAi involved in olfactory learning
posttranscriptional gene silencing by siRNA involved in olfactory learning
biological_process
GO:1903453
RNA interference involved in olfactory learning
Any RNA interference that is involved in olfactory learning.
GOC:TermGenie
GOC:kmv
GO_REF:0000060
PMID:23993094
RNAi involved in olfactory learning
GOC:TermGenie
posttranscriptional gene silencing by siRNA involved in olfactory learning
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
hp
2014-09-25T10:58:06Z
biological_process
GO:1903491
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to simvastatin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
GOC:TermGenie
GOC:sl
GO_REF:0000071
PMID:23100282
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.
hp
2014-09-25T10:58:23Z
biological_process
GO:1903492
response to acetylsalicylate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.
GOC:TermGenie
GO_REF:0000071
PMID:23392654
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
hp
2014-09-25T11:36:42Z
biological_process
GO:1903493
response to clopidogrel
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
GOC:TermGenie
GO_REF:0000071
PMID:23392654
Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:44:47Z
biological_process
GO:1903506
regulation of nucleic acid-templated transcription
Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:44:56Z
down regulation of nucleic acid-templated transcription
down-regulation of nucleic acid-templated transcription
downregulation of nucleic acid-templated transcription
inhibition of nucleic acid-templated transcription
biological_process
GO:1903507
negative regulation of nucleic acid-templated transcription
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
down regulation of nucleic acid-templated transcription
GOC:TermGenie
down-regulation of nucleic acid-templated transcription
GOC:TermGenie
downregulation of nucleic acid-templated transcription
GOC:TermGenie
inhibition of nucleic acid-templated transcription
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:45:04Z
up regulation of nucleic acid-templated transcription
up-regulation of nucleic acid-templated transcription
upregulation of nucleic acid-templated transcription
activation of nucleic acid-templated transcription
biological_process
GO:1903508
positive regulation of nucleic acid-templated transcription
Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
up regulation of nucleic acid-templated transcription
GOC:TermGenie
up-regulation of nucleic acid-templated transcription
GOC:TermGenie
upregulation of nucleic acid-templated transcription
GOC:TermGenie
activation of nucleic acid-templated transcription
GOC:TermGenie
Any process that modulates the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:24:59Z
regulation of cellular secretion
biological_process
GO:1903530
regulation of secretion by cell
Any process that modulates the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
regulation of cellular secretion
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:25:08Z
down regulation of cellular secretion
down regulation of secretion by cell
down-regulation of cellular secretion
down-regulation of secretion by cell
downregulation of cellular secretion
downregulation of secretion by cell
negative regulation of cellular secretion
inhibition of cellular secretion
inhibition of secretion by cell
biological_process
GO:1903531
negative regulation of secretion by cell
Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
down regulation of cellular secretion
GOC:TermGenie
down regulation of secretion by cell
GOC:TermGenie
down-regulation of cellular secretion
GOC:TermGenie
down-regulation of secretion by cell
GOC:TermGenie
downregulation of cellular secretion
GOC:TermGenie
downregulation of secretion by cell
GOC:TermGenie
negative regulation of cellular secretion
GOC:TermGenie
inhibition of cellular secretion
GOC:TermGenie
inhibition of secretion by cell
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:25:17Z
positive regulation of cellular secretion
up regulation of cellular secretion
up regulation of secretion by cell
up-regulation of cellular secretion
up-regulation of secretion by cell
upregulation of cellular secretion
upregulation of secretion by cell
activation of cellular secretion
activation of secretion by cell
biological_process
GO:1903532
positive regulation of secretion by cell
Any process that activates or increases the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
positive regulation of cellular secretion
GOC:TermGenie
up regulation of cellular secretion
GOC:TermGenie
up regulation of secretion by cell
GOC:TermGenie
up-regulation of cellular secretion
GOC:TermGenie
up-regulation of secretion by cell
GOC:TermGenie
upregulation of cellular secretion
GOC:TermGenie
upregulation of secretion by cell
GOC:TermGenie
activation of cellular secretion
GOC:TermGenie
activation of secretion by cell
GOC:TermGenie
Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.
pga
2014-10-20T15:37:25Z
regulation of extracellular vesicular exosome assembly
biological_process
GO:1903551
regulation of extracellular exosome assembly
Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.
GOC:TermGenie
GO_REF:0000058
PMID:24105262
regulation of extracellular vesicular exosome assembly
GOC:vesicles
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.
pga
2014-10-20T15:37:33Z
down regulation of extracellular vesicular exosome assembly
down-regulation of extracellular vesicular exosome assembly
downregulation of extracellular vesicular exosome assembly
negative regulation of extracellular vesicular exosome assembly
inhibition of extracellular vesicular exosome assembly
biological_process
GO:1903552
negative regulation of extracellular exosome assembly
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.
GOC:TermGenie
GO_REF:0000058
PMID:24105262
down regulation of extracellular vesicular exosome assembly
GOC:TermGenie
down-regulation of extracellular vesicular exosome assembly
GOC:TermGenie
downregulation of extracellular vesicular exosome assembly
GOC:TermGenie
negative regulation of extracellular vesicular exosome assembly
GOC:vesicles
inhibition of extracellular vesicular exosome assembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.
pga
2014-10-20T15:37:42Z
up regulation of extracellular vesicular exosome assembly
up-regulation of extracellular vesicular exosome assembly
upregulation of extracellular vesicular exosome assembly
activation of extracellular vesicular exosome assembly
biological_process
positive regulation of extracellular vesicular exosome assembly
GO:1903553
positive regulation of extracellular exosome assembly
Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.
GOC:TermGenie
GO_REF:0000058
PMID:24105262
up regulation of extracellular vesicular exosome assembly
GOC:TermGenie
up-regulation of extracellular vesicular exosome assembly
GOC:TermGenie
upregulation of extracellular vesicular exosome assembly
GOC:TermGenie
activation of extracellular vesicular exosome assembly
GOC:TermGenie
positive regulation of extracellular vesicular exosome assembly
GOC:vesicles
Any vesicle that is part of the extracellular region.
jl
2014-10-22T14:26:11Z
cellular_component
microparticle
GO:1903561
extracellular vesicle
Any vesicle that is part of the extracellular region.
GOC:TermGenie
GOC:pm
GO_REF:0000064
PMID:24769233
microparticle
GOC:vesicles
Any process that modulates the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:11Z
biological_process
GO:1903564
regulation of protein localization to cilium
Any process that modulates the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:20Z
down regulation of protein localization to cilium
down-regulation of protein localization to cilium
downregulation of protein localization to cilium
inhibition of protein localization to cilium
biological_process
GO:1903565
negative regulation of protein localization to cilium
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
down regulation of protein localization to cilium
GOC:TermGenie
down-regulation of protein localization to cilium
GOC:TermGenie
downregulation of protein localization to cilium
GOC:TermGenie
inhibition of protein localization to cilium
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:28Z
up regulation of protein localization to cilium
up-regulation of protein localization to cilium
upregulation of protein localization to cilium
activation of protein localization to cilium
biological_process
GO:1903566
positive regulation of protein localization to cilium
Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
up regulation of protein localization to cilium
GOC:TermGenie
up-regulation of protein localization to cilium
GOC:TermGenie
upregulation of protein localization to cilium
GOC:TermGenie
activation of protein localization to cilium
GOC:TermGenie
Any process that modulates the frequency, rate or extent of ATP metabolic process.
sl
2014-10-30T19:04:24Z
regulation of ATP metabolism
biological_process
GO:1903578
regulation of ATP metabolic process
Any process that modulates the frequency, rate or extent of ATP metabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:20695849
regulation of ATP metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.
sl
2014-10-30T19:04:33Z
down regulation of ATP metabolic process
down regulation of ATP metabolism
down-regulation of ATP metabolic process
down-regulation of ATP metabolism
downregulation of ATP metabolic process
downregulation of ATP metabolism
negative regulation of ATP metabolism
inhibition of ATP metabolic process
inhibition of ATP metabolism
biological_process
GO:1903579
negative regulation of ATP metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:20695849
down regulation of ATP metabolic process
GOC:TermGenie
down regulation of ATP metabolism
GOC:TermGenie
down-regulation of ATP metabolic process
GOC:TermGenie
down-regulation of ATP metabolism
GOC:TermGenie
downregulation of ATP metabolic process
GOC:TermGenie
downregulation of ATP metabolism
GOC:TermGenie
negative regulation of ATP metabolism
GOC:TermGenie
inhibition of ATP metabolic process
GOC:TermGenie
inhibition of ATP metabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of ATP metabolic process.
sl
2014-10-30T19:04:42Z
positive regulation of ATP metabolism
up regulation of ATP metabolic process
up regulation of ATP metabolism
up-regulation of ATP metabolic process
up-regulation of ATP metabolism
upregulation of ATP metabolic process
upregulation of ATP metabolism
activation of ATP metabolic process
activation of ATP metabolism
biological_process
GO:1903580
positive regulation of ATP metabolic process
Any process that activates or increases the frequency, rate or extent of ATP metabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:20695849
positive regulation of ATP metabolism
GOC:TermGenie
up regulation of ATP metabolic process
GOC:TermGenie
up regulation of ATP metabolism
GOC:TermGenie
up-regulation of ATP metabolic process
GOC:TermGenie
up-regulation of ATP metabolism
GOC:TermGenie
upregulation of ATP metabolic process
GOC:TermGenie
upregulation of ATP metabolism
GOC:TermGenie
activation of ATP metabolic process
GOC:TermGenie
activation of ATP metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:17Z
regulation of cytoplasmic streaming
biological_process
GO:1903649
regulation of cytoplasmic transport
Any process that modulates the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
regulation of cytoplasmic streaming
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:26Z
down regulation of cytoplasmic transport
down-regulation of cytoplasmic transport
downregulation of cytoplasmic transport
down regulation of cytoplasmic streaming
down-regulation of cytoplasmic streaming
downregulation of cytoplasmic streaming
inhibition of cytoplasmic streaming
inhibition of cytoplasmic transport
negative regulation of cytoplasmic streaming
biological_process
GO:1903650
negative regulation of cytoplasmic transport
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
down regulation of cytoplasmic transport
GOC:TermGenie
down-regulation of cytoplasmic transport
GOC:TermGenie
downregulation of cytoplasmic transport
GOC:TermGenie
down regulation of cytoplasmic streaming
GOC:TermGenie
down-regulation of cytoplasmic streaming
GOC:TermGenie
downregulation of cytoplasmic streaming
GOC:TermGenie
inhibition of cytoplasmic streaming
GOC:TermGenie
inhibition of cytoplasmic transport
GOC:TermGenie
negative regulation of cytoplasmic streaming
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:34Z
up regulation of cytoplasmic transport
up-regulation of cytoplasmic transport
upregulation of cytoplasmic transport
activation of cytoplasmic streaming
activation of cytoplasmic transport
positive regulation of cytoplasmic streaming
up regulation of cytoplasmic streaming
up-regulation of cytoplasmic streaming
upregulation of cytoplasmic streaming
biological_process
GO:1903651
positive regulation of cytoplasmic transport
Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
up regulation of cytoplasmic transport
GOC:TermGenie
up-regulation of cytoplasmic transport
GOC:TermGenie
upregulation of cytoplasmic transport
GOC:TermGenie
activation of cytoplasmic streaming
GOC:TermGenie
activation of cytoplasmic transport
GOC:TermGenie
positive regulation of cytoplasmic streaming
GOC:TermGenie
up regulation of cytoplasmic streaming
GOC:TermGenie
up-regulation of cytoplasmic streaming
GOC:TermGenie
upregulation of cytoplasmic streaming
GOC:TermGenie
Modulation of host cell motility by a symbiont of that host.
jl
2014-11-24T17:37:56Z
modulation by symbiont of host cell locomotion
regulation by symbiont of host cell motility
biological_process
modulation by symbiont of host cell movement
GO:1903653
modulation by symbiont of host cell motility
Modulation of host cell motility by a symbiont of that host.
GOC:TermGenie
GO_REF:0000063
PMID:25049409
Any process that modulates the frequency, rate or extent of asexual reproduction.
pf
2014-11-26T21:13:24Z
biological_process
GO:1903664
regulation of asexual reproduction
Any process that modulates the frequency, rate or extent of asexual reproduction.
GOC:TermGenie
GO_REF:0000058
PMID:24390142
Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.
pf
2014-11-26T21:13:32Z
down regulation of asexual reproduction
down-regulation of asexual reproduction
downregulation of asexual reproduction
inhibition of asexual reproduction
biological_process
GO:1903665
negative regulation of asexual reproduction
Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.
GOC:TermGenie
GO_REF:0000058
PMID:24390142
down regulation of asexual reproduction
GOC:TermGenie
down-regulation of asexual reproduction
GOC:TermGenie
downregulation of asexual reproduction
GOC:TermGenie
inhibition of asexual reproduction
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of asexual reproduction.
pf
2014-11-26T21:13:40Z
up regulation of asexual reproduction
up-regulation of asexual reproduction
upregulation of asexual reproduction
activation of asexual reproduction
biological_process
GO:1903666
positive regulation of asexual reproduction
Any process that activates or increases the frequency, rate or extent of asexual reproduction.
GOC:TermGenie
GO_REF:0000058
PMID:24390142
up regulation of asexual reproduction
GOC:TermGenie
up-regulation of asexual reproduction
GOC:TermGenie
upregulation of asexual reproduction
GOC:TermGenie
activation of asexual reproduction
GOC:TermGenie
Any process that modulates the frequency, rate or extent of hemopoiesis.
pad
2014-12-04T15:34:13Z
regulation of blood cell biosynthesis
regulation of blood cell formation
regulation of haemopoiesis
regulation of hematopoiesis
biological_process
GO:1903706
An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
regulation of hemopoiesis
Any process that modulates the frequency, rate or extent of hemopoiesis.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:20080761
regulation of blood cell biosynthesis
GOC:TermGenie
regulation of blood cell formation
GOC:TermGenie
regulation of haemopoiesis
GOC:TermGenie
regulation of hematopoiesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.
pad
2014-12-04T15:34:21Z
down regulation of blood cell biosynthesis
down regulation of blood cell formation
down regulation of haemopoiesis
down regulation of hematopoiesis
down regulation of hemopoiesis
down-regulation of blood cell biosynthesis
down-regulation of blood cell formation
down-regulation of haemopoiesis
down-regulation of hematopoiesis
down-regulation of hemopoiesis
downregulation of blood cell biosynthesis
downregulation of blood cell formation
downregulation of haemopoiesis
downregulation of hematopoiesis
downregulation of hemopoiesis
negative regulation of blood cell biosynthesis
negative regulation of blood cell formation
negative regulation of haemopoiesis
negative regulation of hematopoiesis
inhibition of blood cell biosynthesis
inhibition of blood cell formation
inhibition of haemopoiesis
inhibition of hematopoiesis
inhibition of hemopoiesis
biological_process
GO:1903707
An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
negative regulation of hemopoiesis
Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:20080761
down regulation of blood cell biosynthesis
GOC:TermGenie
down regulation of blood cell formation
GOC:TermGenie
down regulation of haemopoiesis
GOC:TermGenie
down regulation of hematopoiesis
GOC:TermGenie
down regulation of hemopoiesis
GOC:TermGenie
down-regulation of blood cell biosynthesis
GOC:TermGenie
down-regulation of blood cell formation
GOC:TermGenie
down-regulation of haemopoiesis
GOC:TermGenie
down-regulation of hematopoiesis
GOC:TermGenie
down-regulation of hemopoiesis
GOC:TermGenie
downregulation of blood cell biosynthesis
GOC:TermGenie
downregulation of blood cell formation
GOC:TermGenie
downregulation of haemopoiesis
GOC:TermGenie
downregulation of hematopoiesis
GOC:TermGenie
downregulation of hemopoiesis
GOC:TermGenie
negative regulation of blood cell biosynthesis
GOC:TermGenie
negative regulation of blood cell formation
GOC:TermGenie
negative regulation of haemopoiesis
GOC:TermGenie
negative regulation of hematopoiesis
GOC:TermGenie
inhibition of blood cell biosynthesis
GOC:TermGenie
inhibition of blood cell formation
GOC:TermGenie
inhibition of haemopoiesis
GOC:TermGenie
inhibition of hematopoiesis
GOC:TermGenie
inhibition of hemopoiesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of hemopoiesis.
pad
2014-12-04T15:34:30Z
positive regulation of blood cell biosynthesis
positive regulation of blood cell formation
positive regulation of haemopoiesis
positive regulation of hematopoiesis
up regulation of blood cell biosynthesis
up regulation of blood cell formation
up regulation of haemopoiesis
up regulation of hematopoiesis
up regulation of hemopoiesis
up-regulation of blood cell biosynthesis
up-regulation of blood cell formation
up-regulation of haemopoiesis
up-regulation of hematopoiesis
up-regulation of hemopoiesis
upregulation of blood cell biosynthesis
upregulation of blood cell formation
upregulation of haemopoiesis
upregulation of hematopoiesis
upregulation of hemopoiesis
activation of blood cell biosynthesis
activation of blood cell formation
activation of haemopoiesis
activation of hematopoiesis
activation of hemopoiesis
biological_process
GO:1903708
An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
positive regulation of hemopoiesis
Any process that activates or increases the frequency, rate or extent of hemopoiesis.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:20080761
positive regulation of blood cell biosynthesis
GOC:TermGenie
positive regulation of blood cell formation
GOC:TermGenie
positive regulation of haemopoiesis
GOC:TermGenie
positive regulation of hematopoiesis
GOC:TermGenie
up regulation of blood cell biosynthesis
GOC:TermGenie
up regulation of blood cell formation
GOC:TermGenie
up regulation of haemopoiesis
GOC:TermGenie
up regulation of hematopoiesis
GOC:TermGenie
up regulation of hemopoiesis
GOC:TermGenie
up-regulation of blood cell biosynthesis
GOC:TermGenie
up-regulation of blood cell formation
GOC:TermGenie
up-regulation of haemopoiesis
GOC:TermGenie
up-regulation of hematopoiesis
GOC:TermGenie
up-regulation of hemopoiesis
GOC:TermGenie
upregulation of blood cell biosynthesis
GOC:TermGenie
upregulation of blood cell formation
GOC:TermGenie
upregulation of haemopoiesis
GOC:TermGenie
upregulation of hematopoiesis
GOC:TermGenie
upregulation of hemopoiesis
GOC:TermGenie
activation of blood cell biosynthesis
GOC:TermGenie
activation of blood cell formation
GOC:TermGenie
activation of haemopoiesis
GOC:TermGenie
activation of hematopoiesis
GOC:TermGenie
activation of hemopoiesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.
sl
2015-01-12T21:50:20Z
down regulation of anion transport
down-regulation of anion transport
downregulation of anion transport
inhibition of anion transport
biological_process
GO:1903792
negative regulation of anion transport
Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.
GOC:TermGenie
GO_REF:0000058
PMID:11336802
down regulation of anion transport
GOC:TermGenie
down-regulation of anion transport
GOC:TermGenie
downregulation of anion transport
GOC:TermGenie
inhibition of anion transport
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of anion transport.
sl
2015-01-12T21:50:30Z
up regulation of anion transport
up-regulation of anion transport
upregulation of anion transport
activation of anion transport
biological_process
GO:1903793
positive regulation of anion transport
Any process that activates or increases the frequency, rate or extent of anion transport.
GOC:TermGenie
GO_REF:0000058
PMID:11336802
up regulation of anion transport
GOC:TermGenie
up-regulation of anion transport
GOC:TermGenie
upregulation of anion transport
GOC:TermGenie
activation of anion transport
GOC:TermGenie
The process in which an organic acid is transported across a membrane.
vw
2015-01-20T10:20:58Z
biological_process
GO:1903825
organic acid transmembrane transport
The process in which an organic acid is transported across a membrane.
GOC:TermGenie
GO_REF:0000069
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:14Z
regulation of cellular protein localisation
regulation of channel localizer activity
biological_process
GO:1903827
regulation of cellular protein localization
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of cellular protein localisation
GOC:TermGenie
regulation of channel localizer activity
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:24Z
down regulation of cellular protein localisation
down regulation of cellular protein localization
down-regulation of cellular protein localisation
down-regulation of cellular protein localization
downregulation of cellular protein localisation
downregulation of cellular protein localization
negative regulation of cellular protein localisation
down regulation of channel localizer activity
down-regulation of channel localizer activity
downregulation of channel localizer activity
inhibition of cellular protein localisation
inhibition of cellular protein localization
inhibition of channel localizer activity
negative regulation of channel localizer activity
biological_process
GO:1903828
negative regulation of cellular protein localization
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of cellular protein localisation
GOC:TermGenie
down regulation of cellular protein localization
GOC:TermGenie
down-regulation of cellular protein localisation
GOC:TermGenie
down-regulation of cellular protein localization
GOC:TermGenie
downregulation of cellular protein localisation
GOC:TermGenie
downregulation of cellular protein localization
GOC:TermGenie
negative regulation of cellular protein localisation
GOC:TermGenie
down regulation of channel localizer activity
GOC:TermGenie
down-regulation of channel localizer activity
GOC:TermGenie
downregulation of channel localizer activity
GOC:TermGenie
inhibition of cellular protein localisation
GOC:TermGenie
inhibition of cellular protein localization
GOC:TermGenie
inhibition of channel localizer activity
GOC:TermGenie
negative regulation of channel localizer activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:33Z
positive regulation of cellular protein localisation
up regulation of cellular protein localisation
up regulation of cellular protein localization
up-regulation of cellular protein localisation
up-regulation of cellular protein localization
upregulation of cellular protein localisation
upregulation of cellular protein localization
activation of cellular protein localisation
activation of cellular protein localization
activation of channel localizer activity
positive regulation of channel localizer activity
up regulation of channel localizer activity
up-regulation of channel localizer activity
upregulation of channel localizer activity
biological_process
GO:1903829
positive regulation of cellular protein localization
Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
positive regulation of cellular protein localisation
GOC:TermGenie
up regulation of cellular protein localisation
GOC:TermGenie
up regulation of cellular protein localization
GOC:TermGenie
up-regulation of cellular protein localisation
GOC:TermGenie
up-regulation of cellular protein localization
GOC:TermGenie
upregulation of cellular protein localisation
GOC:TermGenie
upregulation of cellular protein localization
GOC:TermGenie
activation of cellular protein localisation
GOC:TermGenie
activation of cellular protein localization
GOC:TermGenie
activation of channel localizer activity
GOC:TermGenie
positive regulation of channel localizer activity
GOC:TermGenie
up regulation of channel localizer activity
GOC:TermGenie
up-regulation of channel localizer activity
GOC:TermGenie
upregulation of channel localizer activity
GOC:TermGenie
Any process that modulates the frequency, rate or extent of anion transmembrane transport.
pr
2015-02-25T13:52:25Z
biological_process
GO:1903959
regulation of anion transmembrane transport
Any process that modulates the frequency, rate or extent of anion transmembrane transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.
pr
2015-02-25T13:52:35Z
down regulation of anion transmembrane transport
down-regulation of anion transmembrane transport
downregulation of anion transmembrane transport
inhibition of anion transmembrane transport
biological_process
GO:1903960
negative regulation of anion transmembrane transport
Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of anion transmembrane transport
GOC:TermGenie
down-regulation of anion transmembrane transport
GOC:TermGenie
downregulation of anion transmembrane transport
GOC:TermGenie
inhibition of anion transmembrane transport
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.
pr
2015-02-25T13:52:44Z
up regulation of anion transmembrane transport
up-regulation of anion transmembrane transport
upregulation of anion transmembrane transport
activation of anion transmembrane transport
biological_process
GO:1903961
positive regulation of anion transmembrane transport
Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
up regulation of anion transmembrane transport
GOC:TermGenie
up-regulation of anion transmembrane transport
GOC:TermGenie
upregulation of anion transmembrane transport
GOC:TermGenie
activation of anion transmembrane transport
GOC:TermGenie
Any process that modulates the frequency, rate or extent of eating behavior.
sl
2015-03-05T20:40:22Z
regulation of eating behaviour
biological_process
GO:1903998
regulation of eating behavior
Any process that modulates the frequency, rate or extent of eating behavior.
GOC:TermGenie
GO_REF:0000058
PMID:11961051
regulation of eating behaviour
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.
sl
2015-03-05T20:40:28Z
down regulation of eating behavior
down regulation of eating behaviour
down-regulation of eating behavior
down-regulation of eating behaviour
downregulation of eating behavior
downregulation of eating behaviour
negative regulation of eating behaviour
inhibition of eating behavior
inhibition of eating behaviour
biological_process
GO:1903999
negative regulation of eating behavior
Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.
GOC:TermGenie
GO_REF:0000058
PMID:11961051
down regulation of eating behavior
GOC:TermGenie
down regulation of eating behaviour
GOC:TermGenie
down-regulation of eating behavior
GOC:TermGenie
down-regulation of eating behaviour
GOC:TermGenie
downregulation of eating behavior
GOC:TermGenie
downregulation of eating behaviour
GOC:TermGenie
negative regulation of eating behaviour
GOC:TermGenie
inhibition of eating behavior
GOC:TermGenie
inhibition of eating behaviour
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of eating behavior.
sl
2015-03-05T20:40:35Z
positive regulation of eating behaviour
up regulation of eating behavior
up regulation of eating behaviour
up-regulation of eating behavior
up-regulation of eating behaviour
upregulation of eating behavior
upregulation of eating behaviour
activation of eating behavior
activation of eating behaviour
biological_process
GO:1904000
positive regulation of eating behavior
Any process that activates or increases the frequency, rate or extent of eating behavior.
GOC:TermGenie
GO_REF:0000058
PMID:11961051
positive regulation of eating behaviour
GOC:TermGenie
up regulation of eating behavior
GOC:TermGenie
up regulation of eating behaviour
GOC:TermGenie
up-regulation of eating behavior
GOC:TermGenie
up-regulation of eating behaviour
GOC:TermGenie
upregulation of eating behavior
GOC:TermGenie
upregulation of eating behaviour
GOC:TermGenie
activation of eating behavior
GOC:TermGenie
activation of eating behaviour
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of vasculature development.
sl
2015-03-06T22:17:04Z
up regulation of vasculature development
up-regulation of vasculature development
upregulation of vasculature development
activation of vasculature development
biological_process
activation of vascular system development
positive regulation of vascular system development
up regulation of vascular system development
up-regulation of vascular system development
upregulation of vascular system development
GO:1904018
positive regulation of vasculature development
Any process that activates or increases the frequency, rate or extent of vasculature development.
GOC:TermGenie
GO_REF:0000058
PMID:21472453
up regulation of vasculature development
GOC:TermGenie
up-regulation of vasculature development
GOC:TermGenie
upregulation of vasculature development
GOC:TermGenie
activation of vasculature development
GOC:TermGenie
activation of vascular system development
GOC:TermGenie
positive regulation of vascular system development
GOC:TermGenie