https://orcid.org/0000-0001-7258-9596 https://orcid.org/0000-0002-3315-2794 https://orcid.org/0000-0002-7073-9172 https://orcid.org/0000-0002-7356-1779 https://orcid.org/0000-0002-7509-4801 https://orcid.org/0000-0003-1346-1327 https://orcid.org/0000-0003-1355-892X https://orcid.org/0000-0003-2707-5881 https://orcid.org/0000-0003-4549-588X Cell types that are provisionally defined by experimental techniques such as single cell transcriptomics rather than a straightforward & coherent set of properties. Provisional Cell Ontology See DOI:10.1101/2021.10.10.463703, PMID:34616062, PMID:31435019, PMID:29322913 2023-02-27 symbol definition The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition definition editor note An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. PERSON:Daniel Schober GROUP:OBI:<http://purl.obofoundry.org/obo/obi> IAO:0000116 uberon editor_note true editor_note editor note editor note term replaced by Use on obsolete terms, relating the term to another term that can be used as a substitute Person:Alan Ruttenberg Person:Alan Ruttenberg Add as annotation triples in the granting ontology term replaced by term replaced by synonym cell_type_rank cell_types_count cell_subclasses_count cell_classes_count has_age has_sex has_brain_region has nsforest marker cluster id cell_count nuclei_count fbeta_confidence_score If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL is a defining property chain axiom If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R. is a defining property chain axiom where second argument is reflexive http://purl.org/dc/elements/1.1/description uberon dc-description true dc-description description http://purl.org/dc/elements/1.1/title uberon dc-title true dc-title title http://purl.org/dc/terms/license uberon dcterms-license true dcterms-license license database_cross_reference An alternative label for a class or property which has the exact same meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/20 has exact synonym has_exact_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/20 An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct. https://github.com/information-artifact-ontology/ontology-metadata/issues/21 has related synonym has_related_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/21 is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) this day is part of this year (occurrent parthood) a core relation that holds between a part and its whole Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. part_of BFO:0000050 external quality uberon part_of part_of part of part of part_of http://www.obofoundry.org/ro/#OBO_REL:part_of has part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) a core relation that holds between a whole and its part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. has_part BFO:0000051 external quality uberon has_part has_part has part has part has_part preceded by x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. is preceded by preceded_by http://www.obofoundry.org/ro/#OBO_REL:preceded_by BFO:0000062 external uberon preceded_by preceded_by preceded by preceded by precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. BFO:0000063 external uberon precedes precedes precedes precedes occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t occurs_in unfolds in unfolds_in BFO:0000066 external occurs_in occurs_in Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant occurs in occurs in site of [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t BFO:0000067 uberon contains_process contains_process Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant contains process contains process BSPO:0000096 uberon anterior_to anterior_to anterior to BSPO:0000097 uberon distal_to distal_to distal to BSPO:0000098 uberon dorsal_to dorsal_to dorsal to BSPO:0000099 uberon posterior_to posterior_to posterior to BSPO:0000100 uberon proximal_to proximal_to proximal to BSPO:0000102 uberon ventral_to ventral_to ventral to BSPO:0000107 uberon deep_to deep_to deep to BSPO:0000108 uberon superficial_to superficial_to superficial to BSPO:0000120 uberon in_left_side_of in_left_side_of in left side of BSPO:0000121 uberon in_right_side_of in_right_side_of in right side of BSPO:0000122 uberon in_posterior_side_of in_posterior_side_of in posterior side of BSPO:0000123 uberon in_anterior_side_of in_anterior_side_of in anterior side of BSPO:0000126 uberon in_lateral_side_of in_lateral_side_of in lateral side of BSPO:0001101 uberon in_deep_part_of in_deep_part_of in deep part of BSPO:0001106 uberon proximalmost_part_of proximalmost_part_of proximalmost part of BSPO:0001107 uberon immediately_deep_to immediately_deep_to immediately deep to BSPO:0001108 uberon distalmost_part_of distalmost_part_of distalmost part of BSPO:0005001 uberon intersects_midsagittal_plane_of intersects_midsagittal_plane_of intersects midsagittal plane of BSPO:0015101 uberon in_dorsal_side_of in_dorsal_side_of in dorsal side of GOREL:0002003 external results_in_distribution_of results_in_distribution_of results in distribution of results_in_distribution_of GOREL:0002004 external results_in_fission_of results_in_fission_of results in fission of results_in_fission_of inheres in this fragility is a characteristic of this vase this red color is a characteristic of this apple a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. inheres_in Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing. characteristic of bearer of this apple is bearer of this red color this vase is bearer of this fragility Inverse of characteristic_of A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. bearer_of is bearer of RO:0000053 external bearer_of bearer_of bearer of has characteristic participates in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation a relation between a continuant and a process, in which the continuant is somehow involved in the process participates_in RO:0000056 external uberon participates_in participates_in participates in participates in has participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) a relation between a process and a continuant, in which the continuant is somehow involved in the process Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. has_participant http://www.obofoundry.org/ro/#OBO_REL:has_participant RO:0000057 external has_participant has_participant has participant has participant this catalysis function is a function of this enzyme a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists. function_of is function of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. function of this red color is a quality of this apple a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence A quality inheres in its bearer at all times for which the quality exists. is quality of quality_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. quality of this investigator role is a role of this person a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists. is role of role_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. role of this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function) a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists. has_function has function this apple has quality this red color a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist. has_quality RO:0000086 uberon has_quality has_quality has quality has quality this person has role this investigator role (more colloquially: this person has this role of investigator) a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. has_role has role a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence has disposition inverse of has disposition This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. disposition of is location of my head is the location of my brain this cage is the location of this rat a relation between two independent continuants, the location and the target, in which the target is entirely within the location Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ location_of RO:0001015 uberon location_of location_of location of location of contained in Containment is location not involving parthood, and arises only where some immaterial continuant is involved. Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition): Intended meaning: domain: material entity range: spatial region or site (immaterial continuant) contained_in contained in contains RO:0001019 uberon contains contains contains contains located in my brain is located in my head this rat is located in this cage a relation between two independent continuants, the target and the location, in which the target is entirely within the location Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ located_in http://www.obofoundry.org/ro/#OBO_REL:located_in RO:0001025 uberon located_in located_in located in located in This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation. This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation. the surface of my skin is a 2D boundary of my body a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts. Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape. 2D_boundary_of boundary of is 2D boundary of is boundary of surface of 2D boundary of my body has 2D boundary the surface of my skin a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts. Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape. has boundary has_2D_boundary RO:0002002 uberon has_boundary has_boundary has 2D boundary has 2D boundary http://www.ncbi.nlm.nih.gov/pubmed/22402613 RO:0002005 uberon innervated_by innervated_by innervated_by innervated_by has synaptic terminal of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 RO:0002007 external uberon bounding_layer_of bounding_layer_of A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane. bounding layer of bounding layer of A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. dos 2017-05-24T09:30:46Z RO:0002013 external has_regulatory_component_activity has_regulatory_component_activity has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. dos 2017-05-24T09:31:01Z RO:0002014 external has_negative_regulatory_component_activity has_negative_regulatory_component_activity By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. has negative regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. dos 2017-05-24T09:31:17Z By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. has positive regulatory component activity dos 2017-05-24T09:44:33Z A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. has component activity w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. dos 2017-05-24T09:49:21Z has component process A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. dos 2017-07-20T17:19:37Z occurs across dos 2017-09-17T13:52:24Z Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. directly regulated by Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. GOC:dos Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. dos 2017-09-17T13:52:38Z directly negatively regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. GOC:dos Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. dos 2017-09-17T13:52:47Z directly positively regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. GOC:dos A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. dos 2017-09-22T14:14:36Z This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. has effector activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. GOC:dos David Osumi-Sutherland <= Primitive instance level timing relation between events before or simultaneous with David Osumi-Sutherland RO:0002082 uberon simultaneous_with simultaneous_with t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) simultaneous with simultaneous with David Osumi-Sutherland X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) ends after David Osumi-Sutherland starts_at_end_of RO:0002087 external uberon immediately_preceded_by immediately_preceded_by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) immediately preceded by immediately preceded by David Osumi-Sutherland ends_at_start_of meets RO:0002090 external immediately_precedes immediately_precedes X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) immediately precedes immediately precedes Relation between a neuron and an anatomical structure that its soma is part of. <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y) has soma location has soma location Relation between a neuron and some structure its axon forms (chemical) synapses in. <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0030424> and <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0042734> and <http://purl.obolibrary.org/obo/BFO_0000050> some ( <http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y))) axon synapses in Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?))) synapsed by Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814] Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y) has plasma membrane part Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. synapsed in http://purl.obolibrary.org/obo/BFO_0000051 some ( http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some ( http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)) has postsynaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. synapses in <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?) has presynaptic terminal in Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to. <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?))) N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2)))) synapsed to A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input. has synapse in <http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?) has synaptic terminal in x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) RO:0002131 external uberon overlaps overlaps overlaps overlaps true Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?))) RO:0002134 uberon innervates innervates innervates innervates X continuous_with Y if and only if X and Y share a fiat boundary. connected to The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint) RO:0002150 uberon continuous_with continuous_with continuous with continuous with FMA:85972 two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a. Consider obsoleting and merging with child relation, 'in homology relationship with' RO:0002158 uberon homologous_to homologous_to VBO calls this homologous_to shares ancestor with lactation SubClassOf 'only in taxon' some 'Mammalia' x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria RO:0002160 uberon only_in_taxon only_in_taxon only in taxon x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. RO:0002162 uberon in_taxon in_taxon Connects a biological entity to its taxon of origin. in taxon A is spatially_disjoint_from B if and only if they have no parts in common There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy BFO_0000051 exactly 0 (BFO_0000050 some ?Y) spatially disjoint from https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones). a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b RO:0002170 uberon connected_to connected_to connected to connected to https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern The M8 connects Glasgow and Edinburgh a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones). c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. RO:0002176 uberon connects connects connects connects https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. attached to part of (anatomical structure to anatomical structure) RO:0002177 uberon attaches_to_part_of attaches_to_part_of attached to part of attached to part of true Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure RO:0002178 uberon supplies supplies supplies supplies Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure RO:0002179 uberon drains drains drains drains w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity. For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit. RO:0002180 external uberon has_component has_component has component has component x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y RO:0002202 uberon develops_from develops_from This is the transitive form of the develops from relation develops from develops from inverse of develops from develops into 'neural crest cell' SubClassOf expresses some 'Wnt1 gene' x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process expressed in Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. FBbt RO:0002207 has developmental precursor uberon directly_develops_from directly_develops_from TODO - add child relations from DOS directly develops from directly develops from inverse of directly develops from developmental precursor of directly develops into p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. GO Regulation precludes parthood; the regulatory process may not be within the regulated process. regulates (processual) false RO:0002211 external regulates regulates regulates regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. negatively regulates (process to process) RO:0002212 external negatively_regulates negatively_regulates negatively regulates negatively regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. positively regulates (process to process) RO:0002213 external positively_regulates positively_regulates positively regulates positively regulates mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974) osteoclast SubClassOf 'capable of' some 'bone resorption' A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. has function realized in For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)". RO:0002215 external uberon capable_of capable_of capable of capable of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. has function in RO:0002216 external uberon capable_of_part_of capable_of_part_of capable of part of capable of part of true x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x RO:0002219 uberon surrounded_by surrounded_by surrounded by surrounded by A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts. The epidermis layer of a vertebrate is adjacent to the dermis. The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies. The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used. x adjacent to y if and only if x and y share a boundary. This relation acts as a join point with BSPO RO:0002220 external uberon adjacent_to adjacent_to adjacent to adjacent to A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts. inverse of surrounded by RO:0002221 uberon surrounds surrounds surrounds surrounds Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends. https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. temporally related to inverse of starts with Chris Mungall Allen RO:0002223 uberon starts starts starts starts Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall started by RO:0002224 external uberon starts_with starts_with starts with starts with x develops from part of y if and only if there exists some z such that x develops from z and z is part of y RO:0002225 uberon develops_from_part_of develops_from_part_of develops from part of develops from part of x develops_in y if x is located in y whilst x is developing EHDAA2 Jonathan Bard, EHDAA2 RO:0002226 uberon develops_in develops_in develops in develops in inverse of ends with Chris Mungall RO:0002229 uberon ends ends ends ends x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall finished by RO:0002230 external uberon ends_with ends_with ends with ends with x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y starts with process that occurs in RO:0002231 external has_start_location has_start_location has start location has start location x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y ends with process that occurs in RO:0002232 external has_end_location has_end_location has end location has end location p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. consumes RO:0002233 external has_input has_input has input has input p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. produces RO:0002234 external has_output has_output has output has output Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong] x has developmental contribution from y iff x has some part z such that z develops from y RO:0002254 uberon has_developmental_contribution_from has_developmental_contribution_from has developmental contribution from has developmental contribution from inverse of has developmental contribution from developmentally contributes to t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T induced by Developmental Biology, Gilbert, 8th edition, figure 6.5(F) GO:0001759 We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm] RO:0002256 uberon developmentally_induced_by developmentally_induced_by developmentally induced by developmentally induced by Inverse of developmentally induced by developmentally induces Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p false In general you should not use this relation to make assertions - use one of the more specific relations below this one This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from developmentally preceded by A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision. c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. acts upstream of A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway. c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. affects acts upstream of or within x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage replaces RO:0002285 uberon developmentally_replaces developmentally_replaces developmentally replaces developmentally replaces Inverse of developmentally preceded by developmentally succeeded by 'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue part of developmental precursor of Inverse of 'expressed in' expresses expresses p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint. RO:0002295 external results_in_developmental_progression_of results_in_developmental_progression_of results in developmental progression of results in developmental progression of every flower development (GO:0009908) results in development of some flower (PO:0009046) p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://www.geneontology.org/GO.doc.development.shtml RO:0002296 external results_in_development_of results_in_development_of results in development of results in development of an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists. every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062) GOC:mtg_berkeley_2013 RO:0002297 external results_in_formation_of results_in_formation_of results in formation of results in formation of an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape. tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723) The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. GOC:mtg_berkeley_2013 RO:0002298 external results_in_morphogenesis_of results_in_morphogenesis_of results in morphogenesis of results in morphogenesis of an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474) The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. GOC:mtg_berkeley_2013 RO:0002299 external results_in_maturation_of results_in_maturation_of results in maturation of results in maturation of p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. RO:0002304 external causally_upstream_of,_positive_effect causally_upstream_of,_positive_effect holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y causally upstream of, positive effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. RO:0002305 external causally_upstream_of,_negative_effect causally_upstream_of,_negative_effect causally upstream of, negative effect q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. Because part_of is transitive, inheres in is a sub-relation of characteristic of part of inheres in part of characteristic of part of true an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast. The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity GOC:mtg_berkeley_2013 RO:0002315 external results_in_acquisition_of_features_of results_in_acquisition_of_features_of results in acquisition of features of results in acquisition of features of A relationship that holds via some environmental process Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution. evolutionarily related to A mereological relationship or a topological relationship Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships mereotopologically related to A relationship that holds between entities participating in some developmental process (GO:0032502) Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development developmentally related to a particular instances of akt-2 enables some instance of protein kinase activity c enables p iff c is capable of p and c acts to execute p. catalyzes executes has is catalyzing is executing This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized. enables A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. This is a grouping relation that collects relations used for the purpose of connecting structure and function RO:0002328 uberon functionally_related_to functionally_related_to functionally related to functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. false part of structure that is capable of true holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism genomically related to c involved_in p if and only if c enables some process p', and p' is part of p actively involved in enables part of involved in every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid p regulates levels of c if p regulates some amount (PATO:0000070) of c regulates levels of (process to entity) RO:0002332 external regulates_levels_of regulates_levels_of regulates levels of regulates levels of inverse of enables enabled by inverse of regulates regulated by (processual) RO:0002334 external regulated_by regulated_by regulated by regulated by inverse of negatively regulates RO:0002335 external negatively_regulated_by negatively_regulated_by negatively regulated by negatively regulated by inverse of positively regulates RO:0002336 external positively_regulated_by positively_regulated_by positively regulated by positively regulated by A relationship that holds via some process of localization Do not use this relation directly. It is a grouping relation. related via localization to This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. RO:0002338 external has_target_start_location has_target_start_location has target start location has target start location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. RO:0002339 external has_target_end_location has_target_end_location has target end location has target end location Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l RO:0002341 external results_in_transport_along results_in_transport_along results in transport along results in transport along Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. RO:0002342 external results_in_transport_across results_in_transport_across results in transport across results in transport across 'pollen tube growth' results_in growth_of some 'pollen tube' RO:0002343 external results_in_growth_of results_in_growth_of results in growth of results in growth of 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739) RO:0002344 external results_in_transport_to_from_or_in results_in_transport_to_from_or_in results in transport to from or in results in transport to from or in An organism that is a member of a population of organisms is member of is a mereological relation between a item and a collection. is member of member part of SIO member of has member is a mereological relation between a collection and an item. SIO RO:0002351 uberon has_member has_member has member has member inverse of has input RO:0002352 uberon input_of input_of input of input of inverse of has output RO:0002353 external uberon output_of output_of output of output of formed as result of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a attached to (anatomical structure to anatomical structure) RO:0002371 uberon attaches_to attaches_to attached to attached to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. Wikipedia:Insertion_(anatomy) RO:0002372 uberon has_muscle_origin has_muscle_origin has muscle origin has muscle origin m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. Wikipedia:Insertion_(anatomy) RO:0002373 uberon has_muscle_insertion has_muscle_insertion has muscle insertion has muscle insertion A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves) in branching relationship with https://github.com/obophenotype/uberon/issues/170 Deschutes River tributary_of Columbia River inferior epigastric vein tributary_of external iliac vein x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. drains into drains to tributary channel of http://en.wikipedia.org/wiki/Tributary http://www.medindia.net/glossary/venous_tributary.htm This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries) RO:0002376 uberon tributary_of tributary_of tributary of tributary of http://en.wikipedia.org/wiki/Tributary A lump of clay and a statue x spatially_coextensive_with y if and inly if x and y have the same location This relation is added for formal completeness. It is unlikely to be used in many practical scenarios spatially coextensive with In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y RO:0002380 uberon branching_part_of branching_part_of branching part of branching part of FMA:85994 x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y RO:0002385 uberon has_potential_to_developmentally_contribute_to has_potential_to_developmentally_contribute_to has potential to developmentally contribute to has potential to developmentally contribute to x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y has potential to developmentally induce x has the potential to develop into y iff x develops into y or if x is capable of developing into y RO:0002387 uberon has_potential_to_develop_into has_potential_to_develop_into has potential to develop into has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y has potential to directly develop into inverse of upstream of RO:0002404 external causally_downstream_of causally_downstream_of causally downstream of causally downstream of RO:0002405 external immediately_causally_downstream_of immediately_causally_downstream_of immediately causally downstream of immediately causally downstream of p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q. indirectly activates indirectly positively regulates p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q. indirectly inhibits indirectly negatively regulates relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yield a cross-product of different relation types. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. https://en.wikipedia.org/wiki/Causality p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. RO:0002411 external causally_upstream_of causally_upstream_of causally upstream of causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. RO:0002412 external immediately_causally_upstream_of immediately_causally_upstream_of immediately causally upstream of immediately causally upstream of p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2 influences (processual) RO:0002418 external affects causally_upstream_of_or_within causally_upstream_of_or_within causally upstream of or within inverse of causally upstream of or within RO:0002427 external causally_downstream_of_or_within causally_downstream_of_or_within causally downstream of or within c involved in regulation of p if c is involved in some p' and p' regulates some p involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p involved in positive regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p involved in negative regulation of c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p OWL does not allow defining object properties via a Union involved in or reguates involved in or involved in regulation of A protein that enables activity in a cytosol. c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. executes activity in enables activity in is active in true c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. GOC:cjm GOC:dos p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. RO:0002433 uberon contributes_to_morphology_of contributes_to_morphology_of contributes to morphology of A relationship that holds between two entities in which the processes executed by the two entities are causally connected. This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact. Considering relabeling as 'pairwise interacts with' Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules. in pairwise interaction with interacts with http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ http://purl.obolibrary.org/obo/MI_0914 An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. binds molecularly binds with molecularly interacts with http://purl.obolibrary.org/obo/MI_0915 Axiomatization to GO to be added later An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y. phosphorylates The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. molecularly controls directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. directly inhibits molecularly decreases activity of directly negatively regulates activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. directly activates molecularly increases activity of directly positively regulates activity of This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning. helper property (not for use in curation) 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate' x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. RO:0002473 uberon composed_primarily_of composed_primarily_of composed primarily of p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. has part that occurs in true is kinase activity See notes for inverse relation receives input from This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in. sends output to Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage. relation between physical entity and a process or stage x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). RO:0002488 uberon existence_starts_during existence_starts_during existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). RO:0002489 uberon existence_starts_with existence_starts_with existence starts with x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence overlaps x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) RO:0002491 exists during uberon existence_starts_and_ends_during existence_starts_and_ends_during The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence starts and ends during Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). RO:0002492 ceases_to_exist_during uberon existence_ends_during existence_ends_during The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. https://orcid.org/0000-0002-6601-2165 x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). RO:0002493 uberon existence_ends_with existence_ends_with The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends with x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships RO:0002494 uberon transformation_of transformation_of transformation of x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t RO:0002495 uberon immediate_transformation_of immediate_transformation_of immediate transformation of x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). RO:0002496 uberon existence_starts_during_or_after existence_starts_during_or_after The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence starts during or after x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. RO:0002497 uberon existence_ends_during_or_before existence_ends_during_or_before The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during or before A relationship between a material entity and a process where the material entity has some causal role that influences the process causal agent in process p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between processes depends on The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between entities Forelimb SubClassOf has_skeleton some 'Forelimb skeleton' A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. has supporting framework The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell). RO:0002551 uberon has_skeleton has_skeleton has skeleton causally influenced by (entity-centric) causally influenced by interaction relation helper property http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ molecular interaction relation helper property Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c RO:0002565 external results_in_movement_of results_in_movement_of results in movement of The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). causally influences (entity-centric) causally influences A relation that holds between elements of a musculoskeletal system or its analogs. Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes. biomechanically related to m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. Wikipedia:Antagonist_(muscle) RO:0002568 uberon has_muscle_antagonist has_muscle_antagonist has muscle antagonist inverse of branching part of RO:0002569 uberon has_branching_part has_branching_part has branching part x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. GOC:cjm RO:0002571 uberon lumen_of lumen_of lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity RO:0002572 uberon luminal_space_of luminal_space_of luminal space of inverse of has skeleton RO:0002576 uberon skeleton_of skeleton_of skeleton of p directly regulates q iff p is immediately causally upstream of q and p regulates q. directly regulates (processual) RO:0002578 external directly_regulates directly_regulates directly regulates gland SubClassOf 'has part structure that is capable of' some 'secretion by cell' s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p has part structure that is capable of p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p results in breakdown of RO:0002588 external results_in_assembly_of results_in_assembly_of results in assembly of RO:0002590 external results_in_disassembly_of results_in_disassembly_of results in disassembly of p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c RO:0002592 external results_in_organization_of results_in_organization_of results in organization of A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between material entity and a process pyrethroid -> growth Holds between c and p if and only if c is capable of some activity a, and a regulates p. capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. capable of negatively regulating renin -> arteriolar smooth muscle contraction Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. capable of positively regulating Inverse of 'causal agent in process' RO:0002608 external process_has_causal_agent process_has_causal_agent process has causal agent p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q. directly positively regulates (process to process) RO:0002629 external directly_positively_regulates directly_positively_regulates directly positively regulates p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q. directly negatively regulates (process to process) RO:0002630 external directly_negatively_regulates directly_negatively_regulates directly negatively regulates a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. RO:0003000 external uberon produces produces Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue. produces produces a produced_by b iff some process that occurs_in b has_output a. RO:0003001 external uberon produced_by produced_by produced by produced by p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. 2018-12-13T11:26:17Z RO:0004007 external has_primary_input_or_output has_primary_input_or_output has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. 2018-12-13T11:26:32Z RO:0004008 external has_primary_output has_primary_output has primary output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. GOC:cjm GOC:dph GOC:kva GOC:pt PMID:27812932 p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. 2018-12-13T11:26:56Z RO:0004009 external has_primary_input has_primary_input has primary input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. GOC:cjm GOC:dph GOC:kva GOC:pt PMID:27812932 Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. 2018-01-25T23:20:13Z enables subfunction 2018-01-26T23:49:30Z acts upstream of or within, positive effect 2018-01-26T23:49:51Z acts upstream of or within, negative effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive 2018-01-26T23:53:14Z acts upstream of, positive effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative 2018-01-26T23:53:22Z acts upstream of, negative effect 2018-03-13T23:55:05Z causally upstream of or within, negative effect 2018-03-13T23:55:19Z causally upstream of or within, positive effect The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. regulates activity of p acts on population of c iff c' is a collection, has members of type c, and p has participant c pg 2020-06-08T17:21:33Z RO:0012003 external acts_on_population_of acts_on_population_of acts on population of acts on population of pg 2021-02-26T07:28:29Z RO:0012008 external results_in_fusion_of results_in_fusion_of results in fusion of results in fusion of p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q. pg 2022-09-26T06:07:17Z indirectly causally upstream of p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q. pg 2022-09-26T06:08:01Z indirectly regulates A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region. 2020-07-17T09:26:52Z has synaptic input or output in has synaptic IO in region transcriptomically defined cell type X equivalent to ‘cell’ and (has_exemplar_data value [transcriptomic profile data]) A relation between a material entity and some data in which the data is taken as exemplifying the material entity. C has_exemplar_data y iff x is an instance of C and y is data about x that is taken as exemplifying of C. This relation is not meant to capture the relation between occurrents and data. has exemplar data exemplar data of A relation between a group and another group it is part of but does not fully constitute. X subcluster_of Y iff: X and Y are clusters/groups; X != Y; all members of X are also members of Y. This is used specifically for sets whose members are specified by some set-forming operator (method of grouping) such as clustering analyses in single cell transcriptomics. subcluster of 'Lamp5-like Egln3_1 primary motor cortex GABAergic interneuron (Mus musculus)' subClass_of: has_characterizing_marker_set some 'NS forest marker set of Lamp5-like Egln3_1 MOp (Mouse).'; NS forest marker set of Lamp5-like Egln3_1 SubClass_of: ('has part' some 'Mouse Fbn2') and ('has part' some 'Mouse Chrna7') and ('has part' some 'Mouse Fam19a1'). transcriptomically defined cell type X subClass_of: (has_characterizing_marker_set some S1); S1 has_part some gene 1, S1 has_part some gene 2, S1 has_part some gene 3. A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type. C has_characterizing_marker_set y iff: C is a cell type and y is a collection of genes or proteins whose expression is sufficient to distinguish cell type C from most or all other cell types. This relation is not meant for cases where set of genes/proteins are only useful as markers in some specific context - e.g. in some specific location. In these cases it is recommended to make a more specific cell class restricted to the relevant context. has marker gene combination has marker signature set has characterizing marker set q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. increased in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round. has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. https://orcid.org/0000-0002-6601-2165 'Ly-76 high positive erythrocyte' equivalent to 'enucleate erythrocyte' and (has_high_plasma_membrane_amount some 'lymphocyte antigen 76 (mouse)') A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. has high plasma membrane amount A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. PMID:19243617 'DN2b thymocyte' equivalent to 'DN2 thymocyte' and (has_low_plasma_membrane_amount some 'mast/stem cell growth factor receptor') A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. has low plasma membrane amount A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. PMID:19243617 A diagnostic testing device utilizes a specimen. X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input. See github ticket https://github.com/oborel/obo-relations/issues/497 2021-11-08T12:00:00Z utilizes device utilizes material A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C. RO:0019000 gene_ontology regulates_characteristic regulates_characteristic regulates characteristic A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C. RO:0019001 gene_ontology positively_regulates_characteristic positively_regulates_characteristic positively regulates characteristic A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C. RO:0019002 gene_ontology negatively_regulates_characteristic negatively_regulates_characteristic negatively regulates characteristic p has anatomical participant c iff p has participant c, and c is an anatomical entity 2018-09-26T01:08:58Z RO:0040036 external results_in_changes_to_anatomical_or_cellular_structure results_in_changes_to_anatomical_or_cellular_structure results in changes to anatomical or cellular structure Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison. TODO: Add homeomorphy axiom ECO:0000041 SO:similar_to sameness similar to correspondence resemblance in similarity relationship with Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison. BGEE:curator correspondence Similarity that results from common evolutionary origin. homologous to This broad definition encompasses all the working definitions proposed so far in the literature. in homology relationship with Similarity that results from common evolutionary origin. Homology that is defined by common descent. homology ECO:0000080 RO_proposed_relation:homologous_to SO:0000330 SO:0000853 SO:0000857 SO:homologous_to TAO:homologous_to cladistic homology historical homologous to phylogenetic homology taxic homology true homology in historical homology relationship with Homology that is defined by common descent. ISBN:0123195837 http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y lacks_part http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) lacks_plasma_membrane_part x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. uberon anteriorly_connected_to anteriorly connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern carries uberon channel_for channel for uberon channels_from channels_from uberon channels_into channels_into x is a conduit for y iff y passes through the lumen of x. uberon conduit_for conduit for x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. uberon distally_connected_to distally connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y uberon extends_fibers_into extends_fibers_into X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y https://orcid.org/0000-0002-7073-9172 Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. uberon filtered_through Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed filtered through a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. add to RO uberon indirectly_supplies indirectly_supplies uberon layer_part_of layer part of x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. uberon posteriorly_connected_to posteriorly connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern uberon protects protects x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. uberon proximally_connected_to proximally connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. uberon capable_of_has_part site_of site_of uberon subdivision_of placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B subdivision of Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. uberon synapsed_by synapsed by . uberon transitively_anteriorly_connected_to transitively anteriorly connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern . uberon transitively_distally_connected_to transitively distally connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern . uberon transitively_proximally_connected_to transitively proximally connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern AI158965 AW537698 Galphai3 Gnai-3 Hg1a g(i) alpha-3 guanine nucleotide binding protein, alpha inhibiting 3 guanine nucleotide-binding protein G(i) subunit alpha guanine nucleotide-binding protein G(i) subunit alpha-3 guanine nucleotide-binding protein G(k) subunit alpha heterotrimeric guanine nucleotide-binding protein 1a Gnai3 (Mmus) PB Prbs probasin Pbsn (Mmus) CDC45-related protein Cdc45l PORC-PI-1 cell division control protein 45 homolog cell division cycle 45 homolog Cdc45 (Mmus) H19 (Mmus) 4932420G07Rik sex comb on midleg-like 2 sex comb on midleg-like protein 2 Scml2 (Mmus) APC inhibitor B2GPI activated protein C-binding protein apo-H beta(2)GPI beta-2-GPI beta-2-glycoprotein 1 beta-2-glycoprotein I beta2-GPI Apoh (Mmus) 4430402O11Rik IOP2 iron-only hydrogenase-like protein 2 nuclear prelamin A recognition factor Narf (Mmus) AI447843 caveolin-2 Cav2 (Mmus) AI448727 BCD1 C86813 CPBP Copeb FM2 FM6 Ierepo1 Ierepo3 Krueppel-like factor 6 R75280 Zf9 core promoter element binding protein immediate early response, erythropoietin 1 Klf6 (Mmus) AI315320 AI851618 Scml1 Scml3 polycomb protein SCMH1 sex comb on midleg 1 sex comb on midleg-like 1 sex comb on midleg-like 3 Scmh1 (Mmus) AA959768 CcOX cytochrome c oxidase polypeptide Va cytochrome c oxidase subunit 5A, mitochondrial cytochrome c oxidase subunit Va Cox5a (Mmus) T-box protein 2 T-box transcription factor TBX2 Tbx2 (Mmus) 3930401C23 T-box protein 4 T-box transcription factor TBX4 Tbx4 (Mmus) Y-linked zinc finger protein 2 Zfy-2 zinc finger Y-chromosomal protein 2 Zfy2 (Mmus) LNGFR NGF receptor Tnfrsf16 low affinity neurotrophin receptor p75NTR low-affinity nerve growth factor receptor p75 p75 neurotrophin receptor p75NGFR p75NTR tumor necrosis factor receptor superfamily member 16 Ngfr (Mmus) Int-4 Wnt-3 proto-oncogene Int-4 proto-oncogene Wnt-3 proto-oncogene protein Wnt-3 wingless-related MMTV integration site 3 Wnt3 (Mmus) Wnt14 protein Wnt-9a wingless-type MMTV integration site 14 wingless-type MMTV integration site 9A wnt-14 Wnt9a (Mmus) AV082135 C330004K01Rik Fert Fert2 fer (fms/fps related) protein kinase, testis specific 2 p94-Fer proto-oncogene c-Fer proto-oncogene tyrosine-protein kinase Fer tyrosine-protein kinase Fer Fer (Mmus) 2610005L19Rik AL022631 C230091E20Rik R75304 RAN binding protein 20 Ranbp20 exp6 exportin-6 mKIAA0370 Xpo6 (Mmus) F830016E06Rik Tcfe3 Tfe-3 bHLHe33 mTFE3 transcription factor E3 Tfe3 (Mmus) Axi1 Axil Conductin axin-2 axin-like protein axis inhibition protein 2 Axin2 (Mmus) AA881470 BRCA1-associated ATM activator 1 BRCA1-associated protein required for ATM activation protein 1 Baat1 Brat1 (Mmus) AI414047 AI504261 G-protein subunit alpha-12 Galpha12 g alpha-12 guanine nucleotide-binding protein subunit alpha-12 Gna12 (Mmus) AW260131 BWR1A BWSCR1A HET ITM Impt1 ORCTL-2 Orctl2 Slc22a1l TSSC5 imprinted multi-membrane spanning polyspecific transporter-related protein 1 organic cationic transporter-like 2 p45-BWR1A solute carrier family 22 member 18 tumor suppressing subtransferable candidate 5 Slc22a18 (Mmus) 5033406G21Rik integrin beta-2-like protein pactolus protein pactolus Itgb2l (Mmus) 2010003D20Rik JAM-4 JCAM Jam4 cell adhesion molecule JCAM immunoglobulin superfamily member 5 junction adhesion molecule 4 junctional adhesion molecule 4 Igsf5 (Mmus) 2700059L22Rik PIH1 domain-containing protein 2 Pih1d2 (Mmus) 6332404G05Rik DLTA PDC-E2 PDCE2 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial pyruvate dehydrogenase complex component E2 Dlat (Mmus) 3110001M13Rik AVLL5809 C78570 CII-4 PRO19626 QPs3 cybS succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial succinate dehydrogenase complex subunit D succinate-ubiquinone oxidoreductase cytochrome b small subunit succinate-ubiquinone reductase membrane anchor subunit Sdhd (Mmus) FGF-23 Fgf8b fibroblast growth factor 23 fibroblast growth factor 8b Fgf23 (Mmus) Fgf-6 Fgf7b HBGF-6 HST-2 HSTF-2 fibroblast growth factor 6 fibroblast growth factor 7b heparin secretory-transforming protein 2 heparin-binding growth factor 6 Fgf6 (Mmus) 2600016F06Rik AI256817 BF642806 C86853 G1/S-specific cyclin-D2 Vin-1 Vin1 cD2 Ccnd2 (Mmus) 9930033D15Rik AI790205 C530034M11 mKIAA1624 protein GPR107 Gpr107 (Mmus) A530023G15Rik AI849508 Vgcnl1 sodium leak channel NALCN sodium leak channel non-selective protein voltage gated channel like 1 voltage gated channel-like protein 1 Nalcn (Mmus) 1500005I02Rik BTB/POZ domain-containing protein 17 Tango10a Btbd17 (Mmus) AI450778 Schlafen family member 4 schlafen 4 Slfn4 (Mmus) tyrosine 3-hydroxylase tyrosine 3-monooxygenase Th (Mmus) AA986540 Ins-2 InsII Mody Mody4 insulin-2 proinsulin Ins2 (Mmus) ENaC gamma SCNEG amiloride-sensitive sodium channel subunit gamma epithelial Na(+) channel subunit gamma gamma-ENaC gamma-NaCH nonvoltage-gated sodium channel 1 subunit gamma Scnn1g (Mmus) AW495265 DRP-2 dystrophin-related protein 2 Drp2 (Mmus) AML1-regulated transmembrane protein 1 AW208513 Art-1 BB235973 D7Wsu37e Phemx Tssc6 pan hematopoietic expression protein Phemx tetraspanin-32 tspan-32 tumor-suppressing subchromosomal transferable fragment 6 Tspan32 (Mmus) LH2A LIM homeo box protein 2 LIM/homeobox protein Lhx2 Lh-2 Lim2 ap apterous homeobox protein LH-2 Lhx2 (Mmus) 4632413B12Rik C-type lectin domain family 2 member G C-type lectin-related protein C Clr-c Clr-d Clrc Clrd Clrx Ddv10 Ocilrp1 ocil-related protein 1 osteoclast inhibitory lectin related protein osteoclast inhibitory lectin-related protein 1 Clec2g (Mmus) 2310004P21Rik AV028449 GMP reductase 1 GMPR 1 guanosine 5'-monophosphate oxidoreductase 1 guanosine monophosphate reductase 1 Gmpr (Mmus) glycine receptor 48 kDa subunit glycine receptor strychnine-binding subunit glycine receptor subunit alpha-1 nmf11 oscillator ot spasmodic spd Glra1 (Mmus) FXY2 RING-type E3 ubiquitin transferase MID2 Trim1 midline defect 2 probable E3 ubiquitin-protein ligase MID2 tripartite motif-containing protein 1 Mid2 (Mmus) AA960166 AL022677 E3 ubiquitin/ISG15 ligase TRIM25 EFP RING-type E3 ubiquitin transferase TRIM25 Zfp147 estrogen-responsive finger protein tripartite motif protein 25 tripartite motif-containing protein 25 ubiquitin/ISG15-conjugating enzyme TRIM25 zinc finger protein 147 Trim25 (Mmus) C87606 DAG kinase epsilon DAGK6 DGK DGK-epsilon diacylglycerol kinase epsilon diglyceride kinase epsilon Dgke (Mmus) 2410018F01Rik 4833411K15Rik AI957256 Risc retinoid-inducible serine carboxypeptidase retinoid-inducible serine caroboxypeptidase retinoid-inducible serine caroboxypetidase serine caroboxypeptidase 1 Scpep1 (Mmus) Rox bHLHd3 max-binding protein MNT myc antagonist MNT Mnt (Mmus) 2E6 AI528527 Cd18 LAD LCAMB Lfa1 MF17 Mac-1 beta cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta complement receptor C3 subunit beta integrin beta-2 lymphocyte function associated antigen 1 macrophage antigen-1 beta Itgb2 (Mmus) 2310057G13Rik 5'-deoxynucleotidase HDDC2 HD domain-containing protein 2 Hddc2 (Mmus) D53 tumor protein D53 Tpd52l1 (Mmus) PEAMT PEMT2 PLMT Pempt Pempt2 phosphatidylethanolamine N-methyltransferase phospholipid methyltransferase Pemt (Mmus) AA960649 ARC-1 E-cad E-cadherin Ecad L-CAM UVO Um cadherin-1 epithelial cadherin uvomorulin Cdh1 (Mmus) AW120700 R-CAD R-Cadh R-cadherin Rcad cadherin-4 retina cadherin retinal cadherin Cdh4 (Mmus) Mt-CK ScCKmit U-MtCK UbCKmit acidic-type mitochondrial creatine kinase creatine kinase U-type, mitochondrial mi-CK mia-CK ubiquitous mitochondrial creatine kinase Ckmt1 (Mmus) B-cell CLL/lymphoma 6 member B protein Bazf BcL6-associated zinc finger protein Bcl6b (Mmus) C-type lectin domain family 10 member A CD301a M-ASGP-BP-1 Mgl Mgl1 macrophage asialoglycoprotein-binding protein 1 macrophage galactose N-acetyl-galactosamine specific lectin 1 Clec10a (Mmus) 12S-LOX 12S-lipoxygenase 9930022G08Rik Alox12p P-12LO arachidonate (12S)-lipoxygenase arachidonate (15S)-lipoxygenase arachidonate 12-lipoxygenase, 12S-type arachidonate 15-lipoxygenase,15S-type linoleate 13S-lipoxygenase lipoxin synthase 12-LO platelet-type lipoxygenase 12 polyunsaturated fatty acid lipoxygenase ALOX12 Alox12 (Mmus) Arvcf (Mmus) Comt1 D16Wsu103e D330014B15Rik catechol O-methyltransferase catechol-O-methyltransferase 1 Comt (Mmus) 2310009A18Rik AI450277 RNA 3'-terminal phosphate cyclase RNA cyclase RNA terminal phosphate cyclase domain 1 RNA terminal phosphate cyclase domain-containing protein 1 RNA-3'-phosphate cyclase RPC Rtcd1 Rtca (Mmus) BCKAD E2 BCKAD-E2 D3Wsu60e branched-chain alpha-keto acid dehydrogenase complex component E2 branched-chain alpha-ketoacid dehydrogenase, E2 subunit dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex dihydrolipoyl transacylase dihydrolipoyllysine-residue (2-methylpropanoyl)transferase lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial part of the BCKAD complex Dbt (Mmus) AI314727 Brbp DAZ-associated protein 2 Gcap28 Prtb deleted in azoospermia-associated protein 2 granule cell antiserum positive 28 gt6-12 mKIAA0058 proline-rich protein expressed in brain Dazap2 (Mmus) 1500019M23Rik MCT-1 malignant T-cell-amplified sequence 1 multiple copies T-cell malignancies 1 Mcts1 (Mmus) E030011C07Rik GTP-binding protein REM 1 RAS-like GTP binding protein Rem Ras Rem rad and Gem-like GTP-binding protein 1 Rem1 (Mmus) MMIP-2 Max dimerization protein member-interacting protein 2 Mmip2 RING finger protein 17 TDRD4 mad member-interacting protein 2 Rnf17 (Mmus) Trappc10 (Mmus) BC029157 cerebral cavernous malformation 2 homolog cerebral cavernous malformations protein 2 homolog malcavernin osmosensing scaffold for MEKK3 Ccm2 (Mmus) whey acidic protein Wap (Mmus) 2310042P22Rik AA120735 AA408001 AI527316 Cpr2 FAST kinase domain-containing protein 4 R74877 Tb-12 cell cycle progression 2 protein protein TBRG4 transforming growth factor beta regulator 4 Tbrg4 (Mmus) D16Ertd61e epitheliasin plasmic transmembrane protein X transmembrane protease serine 2 Tmprss2 (Mmus) Mx1 (Mmus) FAPalpha SIMP dipeptidyl peptidase FAP fibroblast activation protein alpha gelatine degradation protease FAP integral membrane serine protease post-proline cleaving enzyme prolyl endopeptidase FAP seprase serine integral membrane protease surface-expressed protease Fap (Mmus) GLP-1 Glu PPG glucagon-like peptide I pro-glucagon Gcg (Mmus) 1010001N11Rik CI-39kD NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH-ubiquinone oxidoreductase 39 kDa subunit complex I-39kD Ndufa9 (Mmus) EGF-like protein 6 MAM and EGF domains-containing gene protein Maeg epidermal growth factor-like protein 6 Egfl6 (Mmus) Hck-3 Lsk Lskt leukocyte C-terminal Src kinase lymphocyte cell-specific protein-tyrosine kinase p56<lck> p56Lck proto-oncogene tyrosine-protein kinase LCK Lck (Mmus) 1700014N07Rik 4930594I21Rik Stk22c Stk22d Tsk-3 Tssk-3 Tssk3b serine/threonine kinase 22C (spermiogenesis associated) serine/threonine-protein kinase 22C spermiogenesis associated serine/threonine kinase 22D testis-specific kinase 3 testis-specific serine/threonine kinase 3b testis-specific serine/threonine-protein kinase 3 Tssk3 (Mmus) 3010022N24Rik 4732477G22Rik 6430526E05 9130022E09Rik AU040881 CTTNBP2 intron retention form Cortbp2 ORF4 cortactin-binding protein 2 cortactin-binding protein 2 intron retention form mKIAA1758 Cttnbp2 (Mmus) UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 galNAc-T1 polypeptide GalNAc transferase 1 polypeptide N-acetylgalactosaminyltransferase 1 pp-GaNTase 1 ppGaNTase-T1 protein-UDP acetylgalactosaminyltransferase 1 Galnt1 (Mmus) B130010J22Rik Myf-5 bHLHc2 myogenic factor 5 myogenic regulatory factor MYF-5 Myf5 (Mmus) 2610002L04Rik C81377 E3 ubiquitin-protein ligase makorin-2 Makorin RING zinc-finger protein 2 RING-type E3 ubiquitin transferase makorin-2 probable E3 ubiquitin-protein ligase makorin-2 Mkrn2 (Mmus) Nr1c3 PPAR-gamma PPAR-gamma2 PPARgamma PPARgamma2 nuclear receptor subfamily 1 group C member 3 peroxisome proliferator activated receptor gamma 2 peroxisome proliferator activated receptor gamma 4 peroxisome proliferator-activated receptor gamma Pparg (Mmus) 6430402F14Rik AA990557 BB129353 Craf1 Craf1 transforming D830050J10Rik RAF proto-oncogene serine/threonine-protein kinase Raf-1 c-Raf cRaf murine sarcoma 3611 oncogene 1 proto-oncogene c-RAF v-Raf Raf1 (Mmus) Diff6 Pnutl3 Sept1 differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase) differentiation protein 6 peanut-like protein 3 protein Diff6 septin-1 Sept1 (Mmus) PDGF subunit B PDGF-2 PDGF-B Sis c-sis platelet-derived growth factor B chain platelet-derived growth factor beta polypeptide platelet-derived growth factor subunit B proto-oncogene c-Sis Pdgfb (Mmus) AI115505 AI427544 Acvrlk1 Alk1 SKR3 TGF-B superfamily receptor type I TSR-I activin receptor-like kinase 1 serine/threonine-protein kinase receptor R3 Acvrl1 (Mmus) GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein GRP1-associated scaffold protein Grasp general receptor for phosphoinositides 1-associated scaffold protein Grasp (Mmus) 6820432J04 ALK-4 ActR-IB ActRIB Acvrlk4 Alk4 SKR2 activin receptor type IB activin receptor type-1B activin receptor-like kinase 4 serine/threonine-protein kinase receptor R2 Acvr1b (Mmus) 2900016I08Rik A730055F12Rik AU042072 Srebf1 TOM1-like protein 2 myb1-like protein 2 target of Myb-like protein 2 Tom1l2 (Mmus) 2010310L10Rik 2210401D16Rik A33 antigen BB116197 cell surface A33 antigen mA33 Gpa33 (Mmus) Hzf Zfp385 Znf385a hematopoietic zinc finger protein zinc finger protein 385 zinc finger protein 385A Zfp385a (Mmus) CD49 antigen-like family member E Cd49e Fnra VLA5 fibronectin receptor alpha polypeptide fibronectin receptor subunit alpha integrin alpha-5 integrin alpha-F Itga5 (Mmus) Gabra2 (Mmus) 2610003I18Rik 2610312E17Rik C79984 MEP-50 WD repeat-containing protein 77 methylosome protein 50 p44/MEP50 Wdr77 (Mmus) A3AR A3R AA3R ARA3 G-protein coupled receptor 2 Gpcr2 adenosine receptor A3 Adora3 (Mmus) ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase subunit b, mitochondrial ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 ATPase subunit b Atp5f1 C76477 Atp5f1 (Mmus) 2010306G03Rik AV220920 SRY-box containing gene 9 mKIAA4243 mSox9 transcription factor SOX-9 Sox9 (Mmus) AU-rich element RNA-binding protein 1 Auf1 Hnrpd heterogeneous nuclear ribonucleoprotein D0 hnRNP D0 Hnrnpd (Mmus) 100040603 AGS2 Activator of G-protein signaling 2 Dynein light chain Tctex-type 1 Dynlt1 Dynlt1d T-complex testis-specific protein 1 Tctel1 Tctex-1 Tctex1 dynein light chain Tctex-type 1C dynein light chain Tctex-type 1D Dynlt1c (Mmus) 1110036E10Rik AI875855 SUN-CoR nuclear DNA-binding protein nuclear nucleic acid-binding protein C1D small unique nuclear receptor corepressor C1d (Mmus) AA408702 AW215435 GM2-AP SAP-3 cerebroside sulfate activator protein ganglioside GM2 activator shingolipid activator protein 3 sphingolipid activator protein 3 Gm2a (Mmus) 2010007K12Rik A630036P20Rik AA432855 AI450393 AI643869 BB155247 BB235701 Ccm1 cerebral cavernous malformations 1 protein homolog krev interaction trapped 1 krev interaction trapped protein 1 Krit1 (Mmus) Clc4-2 Clcn4-2 H(+)/Cl(-) exchange transporter 4 chloride channel 4-2 chloride channel protein 4 chloride transporter ClC-4 clC-4 voltage-gated chloride channel ClC-4A Clcn4 (Mmus) V2r13 V2r3 vomeronasal 2, receptor 88 vomeronasal 2, receptor, 13 vomeronasal 2, receptor, 3 vomeronasal organ family 2, receptor, 13 vomeronasal organ family 2, receptor, 3 vomeronasal receptor Vmn2r88 Vmn2r88 (Mmus) BC021919 G protein-coupled receptor GRM6 G protein-coupled receptor, family C, group 1, member F Gm3 Gprc1f mGluR6 metabotropic glutamate receptor 6 nerg1 nob2 nob3 nob4 Grm6 (Mmus) Sema W semaphorin-4F semaphorin-W Sema4f (Mmus) AI642394 HK II HKII hexokinase type II hexokinase-2 Hk2 (Mmus) MAJN MyoPDZ MysPDZ SP-R210 molecule associated with JAK3 N-terminus myosin XVIIIb myosin containing a PDZ domain surfactant protein receptor SP-R210 unconventional myosin-XVIIIa Myo18a (Mmus) BSRP-C D11Bhm177e brain-specific receptor-like protein C seizure protein 6 sez-6 Sez6 (Mmus) 0610007K21Rik 0610012J07Rik 3-HAO 3-HAOxase 3-hydroxyanthranilate 3,4-dioxygenase 3-hydroxyanthranilate oxygenase 3-hydroxyanthranilic acid dioxygenase 3HAO HAD Haao (Mmus) AI463198 B7 B7-Ag CAMPATH-1 CAMPATH-1 antigen CLS1 MB7 lymphocyte differentiation antigen B7 Cd52 (Mmus) 1300007F04Rik abhydrolase domain-containing protein 15 alpha/beta hydrolase domain-containing protein 15 protein ABHD15 Abhd15 (Mmus) Hox-2.2 homeo box B6 homeobox protein Hox-2.2 homeobox protein Hox-B6 homeobox protein MH-22A Hoxb6 (Mmus) Lor2 Loxl2 lysyl oxidase homolog 3 lysyl oxidase-like 2 lysyl oxidase-like protein 3 lysyl oxidase-related protein 2 Loxl3 (Mmus) D12Ertd644e protein TCL1B5 Tcl1b5 (Mmus) BT Btn butyrophilin subfamily 1 member A1 Btn1a1 (Mmus) A930006P13Rik AI461839 AW536563 Pcaf histone acetylase PCAF histone acetyltransferase KAT2B histone acetyltransferase PCAF lysine acetyltransferase 2B p/CAF p300/CBP-associated factor spermidine acetyltransferase KAT2B Kat2b (Mmus) C030027M18Rik ras-related protein Rab-5B Rab5b (Mmus) BA3/A1 Cryb beta-A1-crystallin beta-A3/A1-crystallin beta-crystallin A1 Cryba1 (Mmus) D6Ertd14e DNA (cytosine-5)-methyltransferase 3-like ecat7 Dnmt3l (Mmus) APECED protein homolog autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog autoimmune regulator autoimmune regulator AIRE1a Aire (Mmus) AU044799 B7 homolog 2 B7-H2 B7-like protein Gl50 B7-related protein 1 B7RP-1 B7h BG071784 GI50 GL50 GL50-B ICOS ligand ICOS-L Icoslg LICOS Ly115l mKIAA0653 Icosl (Mmus) AI452278 AU015315 Cmar PGN cell matrix adhesion regulator paraplegin spastic paraplegia 7 homolog spastic paraplegia 7 protein Spg7 (Mmus) Sult-x1 Sultx1 sulfotransferase family 5A, member 1 sulfotransferase related gene X1 sulfotransferase-related protein SULT-X1 Sult5a1 (Mmus) 60S ribosomal protein L13 A52 L13 Rpl13 (Mmus) 2900018H07Rik Pcoln3 charged multivesicular body protein 1a chromatin modifying protein 1A chromatin-modifying protein 1a procollagen (type III) N-endopeptidase Chmp1a (Mmus) 5031405K23Rik 70kDa AA589576 AW557552 RF-A RF-A protein 1 RP-A RP-A p70 Rpa replication factor A protein 1 replication protein A 70 kDa DNA-binding subunit Rpa1 (Mmus) AI195227 EPC-1 Pedf Pedfl SDF-3 Sdf3 alpha-2 antiplasmin caspin pigment epithelium-derived factor serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 serine (or cysteine) proteinase inhibitor, clade F), member 1 serine (or cysteine) proteinase inhibitor, clade F, member 1 serpin F1 stromal cell-derived factor 3 Serpinf1 (Mmus) GCP-3 GCP3 Spc98p gamma-tubulin complex component 3 spindle pole body protein Tubgcp3 (Mmus) M-OR-1 MOP receptor MOP-R MOR-1 MOR-1O Oprm mor mu opioid receptor MOR-1BI mu opioid receptor MOR-1P mu-type opioid receptor muOR Oprm1 (Mmus) 2810426M17Rik 44kDa AI326118 AW489084 BN51 (BHK21) temperature sensitivity complementing BN51T DNA-directed RNA polymerase III subunit C4 DNA-directed RNA polymerase III subunit D DNA-directed RNA polymerase III subunit RPC4 RNA polymerase III subunit C4 RPC4 TSBN51 Polr3d (Mmus) AI465550 T-cell-specific transcription factor 1 TCF-1 Tcf1 transcription factor 7 Tcf7 (Mmus) ATP-dependent RNA helicase DDX3X D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 D1Pas1-related sequence 2 D1Pas1-rs2 DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 DEAD box RNA helicase DEAD3 DEAD box protein 3, X-chromosomal DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked Ddx3 Fin14 embryonic RNA helicase fibroblast growth factor inducible 14 mDEAD3 Ddx3x (Mmus) CD212 IL-12 receptor beta component IL-12 receptor subunit beta-1 IL-12R subunit beta-1 IL-12R-beta-1 IL-12R[b] Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) interleukin-12 receptor subunit beta-1 Il12rb1 (Mmus) NIS Na(+)/I(-) cotransporter Na(+)/I(-) symporter sodium-iodide symporter sodium/iodide cotransporter solute carrier family 5 member 5 Slc5a5 (Mmus) KCa2.3 SK3 SKCA3 SKCa 3 small conductance calcium-activated potassium channel 3 small conductance calcium-activated potassium channel protein 3 Kcnn3 (Mmus) 2900074J03Rik 6430526O11Rik AW045245 ubiquitin carboxyl-terminal hydrolase 32 ubiquitin specific protease 32 Usp32 (Mmus) AW456718 CA-IV Ca4 carbonate dehydratase IV carbonic anhydrase 4 carbonic anhydrase IV Car4 (Mmus) AI196535 TGR TR2 thioredoxin and glutathione reductase thioredoxin reductase 3 thioredoxin reductase TR2 Txnrd3 (Mmus) APT1LG1 CD178 CD95 ligand CD95-L CD95L Fas antigen ligand Fas-L Faslg Tnfsf6 Tnlg1a generalized lymphoproliferative disease gld tumor necrosis factor ligand 1a tumor necrosis factor ligand superfamily member 6 Fasl (Mmus) Gm632 Znf512b zinc finger protein 512B Zfp512b (Mmus) 2610314I24Rik AU018536 Csp DnaJ (Hsp40) homolog, subfamily C, member 5 cysteine string protein dnaJ homolog subfamily C member 5 Dnajc5 (Mmus) 2810411G23Rik AU016537 C86069 D54 tumor protein D54 Tpd52l2 (Mmus) FMRP Fmr-1 synaptic functional regulator FMR1 Fmr1 (Mmus) 2810047E18Rik B-cell CLL/lymphoma 11A B-cell lymphoma/leukemia 11A BCL-11A COUP-TF interacting protein 1 Ctip1 D930021L15Rik EVI-9 Evi9 Evi9a Evi9b Evi9c ecotropic viral integration site 9 protein mKIAA1809 myeloid leukemia Bcl11a (Mmus) B-cell IgG differentiation factor B-cell growth factor 1 B-cell stimulatory factor 1 BSF-1 IGG1 induction factor Il-4 interleukin-4 lymphocyte stimulatory factor 1 Il4 (Mmus) 24 kDa intrinsic membrane protein 24 kDa peroxisomal intrinsic membrane protein 3010018P03Rik Pmp24 peroxisomal membrane protein 4 Pxmp4 (Mmus) Dlgh3 SAP102 discs, large homolog 3 disks large homolog 3 mKIAA1232 synapse-associated protein 102 Dlg3 (Mmus) ESTM55 Gm16314 Me49f07 WD repeat-containing protein 14 WD40 repeat-containing protein deleted in VCFS Wdr14 Wdvcf g protein subunit beta-like protein 1 guanine nucleotide-binding protein subunit beta-like protein 1 Gnb1l (Mmus) dopamine beta-hydroxylase dopamine beta-monooxygenase Dbh (Mmus) MMP-11 SL-3 ST3 Stmy3 matrix metalloproteinase 11 stromelysin 3 stromelysin-3 Mmp11 (Mmus) AU020204 BRG1-associated factor 47 Baf47 Ini1 SNF5 homolog SNF5/INI1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Snf5 integrase interactor 1 protein mSNF5 Smarcb1 (Mmus) 8HS-20 AI528709 Vpreb-3 pre-B lymphocyte protein 3 Vpreb3 (Mmus) AA410023 HIP1-related protein huntingtin-interacting protein 1-related protein mKIAA0655 Hip1r (Mmus) 28S rRNA (cytosine-C(5))-methyltransferase 9830109N13Rik AI326939 Nol1r Wbscr20 Wbscr20a Williams Beuren syndrome chromosome region 20A homolog Williams-Beuren syndrome critical region protein 20 probable 28S rRNA (cytosine-C(5))-methyltransferase putative methyltransferase NSUN5 williams-Beuren syndrome chromosomal region 20A protein homolog Nsun5 (Mmus) 2900052H09Rik DNA topoisomerase I, mitochondrial mitochondrial topoisomerase I Top1mt (Mmus) Hox-1.8 Hoxa-10 homeo box A10 homeobox protein Hox-1.8 homeobox protein Hox-A10 Hoxa10 (Mmus) AV206827 Hox-1.4 homeo box A4 homeobox protein Hox-1.4 homeobox protein Hox-A4 homeobox protein MH-3 Hoxa4 (Mmus) Gm38393 (Mmus) AI325305 MMP-X1 MT-MMP-1 MT1-MMP Membrane type 1-MMP matrix metalloproteinase 14 (membrane-inserted) matrix metalloproteinase-14 membrane-type-1 matrix metalloproteinase sabe type 1 matrix metalloprotease 14 Mmp14 (Mmus) AI790233 Y+L amino acid transporter 1 my+lat1 solute carrier family 7 member 7 y(+)L-type amino acid transporter 1 y+LAT-1 y+LAT1 Slc7a7 (Mmus) 1810020M02Rik AI894287 OXA1-like protein mitochondrial inner membrane protein OXA1L oxidase assembly 1-like protein Oxa1l (Mmus) 2700008B19Rik BB135312 BB249351 HEAT repeat-containing protein 6 Heatr6 (Mmus) AI323804 C-C motif chemokine 3 G0S19-1 L2G25B LD78alpha MIP-1-alpha MIP-1alpha MIP1 (a) MIP1-(a) MIP1-alpha Mip1a SIS-alpha Scya3 TY-5 heparin-binding chemotaxis protein macrophage inflammatory protein 1-alpha macrophage inflammatory protein-1alpha small-inducible cytokine A3 Ccl3 (Mmus) Expi Kal1 Kallmann syndrome 1 sequence WAP four-disulfide core domain protein 18 WDNM1 extracellular peptidase inhibitor extracellular proteinase inhibitor Wfdc18 (Mmus) 1810015M19Rik Cd242 ICAM-4 LW glycoprotein intercellular adhesion molecule 4 Icam4 (Mmus) 6230405A16Rik TEG-267 Tex261 Tex267 interleukin enhancer-binding factor 2 nuclear factor of activated T-cells 45 kDa testis expressed gene 267 Ilf2 (Mmus) 2500003M10Rik Fop Friend of PRMT1 protein Srag chromatin target of PRMT1 protein small arginine- and glycine-rich protein small protein rich in arginine and glycine Chtop (Mmus) 25kDa AA407989 AV026596 BLOC-1 subunit 7 Bloc1s7 SNARE-associated protein Snapin Snap25bp Snapap biogenesis of lysosome-related organelles complex 1 subunit 7 synaptosomal-associated protein 25 binding protein synaptosomal-associated protein, 25 kDa, binding protein Snapin (Mmus) 18A2 42a Capl FSp1 Fibroblast-specific protein 1 Mts1 PeL98 calvasculin metastasin metastatic cell protein pk9a placental calcium-binding protein protein 18A2 protein Mts1 protein S100-A4 S100a4 (Mmus) S100E protein S100-A3 S100a3 (Mmus) S100D9 protein S100-A5 S100a5 (Mmus) 2A9 5B10 CALCYCLIN Cacy PRA S100 calcium-binding protein A6 calcium binding protein A6 (calcyclin) prolactin receptor-associated protein protein S100-A6 S100a6 (Mmus) Nav1.4 SkM1 mH2 sodium channel alpha-subunit sodium channel protein skeletal muscle subunit alpha sodium channel protein type 4 subunit alpha sodium channel protein type IV subunit alpha sodium channel, voltage-gated, type IV, alpha polypeptide voltage-gated sodium channel subunit alpha Nav1.4 Scn4a (Mmus) CD102 Icam-2 Ly-60 intercellular adhesion molecule 2 lymphocyte function-associated AG-1 counter-receptor Icam2 (Mmus) BMK-1 BMK1 ERK-5 ERK5 Erk5-T MAPK 7 PRKM7 b2b2346Clo big MAP kinase 1 extracellular signal-regulated kinase 5 mitogen-activated protein kinase 7 Mapk7 (Mmus) 9530051D10Rik AA536924 EPS-15-interacting protein 2 Ibp2 epsin-2 intersectin-EH-binding protein 2 Epn2 (Mmus) AW045994 B9 B9 domain-containing protein 1 Eppb9 endothelial precursor cells protein B9 B9d1 (Mmus) AI605202 SEC24 protein transport protein Sec24B Sec24b (Mmus) C330016O10Rik NEDD4-binding protein 3 N4bp3 (Mmus) 0610039K22Rik E3 ubiquitin-protein transferase RMND5B Gid2 protein RMD5 homolog B Rmnd5b (Mmus) 2410130M07Rik D11Ertd175e H/ACA ribonucleoprotein complex subunit 2 H/ACA small nucleolar RNPs NHP2 ribonucleoprotein homolog Nola2 nucleolar protein family A, member 2 snoRNP protein NHP2 Nhp2 (Mmus) 1300018I17Rik 2410004N05Rik 5-day ovary-specific transcript 1 protein 5DOS1 VPS9 domain-containing protein 1 VSP9 domain containing 1 Vsp9d1 Vps9d1 (Mmus) AW048709 D8Ertd370e D8Ertd377e Znf276 zfp-276 zinc finger protein 276 Zfp276 (Mmus) C1q and tumor necrosis factor-related protein 11 C1q/TNF-related protein 11 C1qTNF11 C1qtnf11 CTRP11 complement C1q-like protein 4 C1ql4 (Mmus) 0610009O03Rik Tetran major facilitator superfamily domain-containing protein 10 tetracycline transporter-like protein Mfsd10 (Mmus) 2700072H04Rik AI266952 Luzp leucine zipper motif-containing protein leucine zipper protein 1 mFLJ00226 Luzp1 (Mmus) Na(+)/dicarboxylate cotransporter 1 Nadc-1 Nadc1 mNaDC-1 renal sodium/dicarboxylate cotransporter sodium/dicarboxylate co-transporter solute carrier family 13 member 2 Slc13a2 (Mmus) AW536343 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 BTB/POZ domain-containing protein KCTD10 C87062 mBACURD3 potassium channel tetramerization domain-containing 10 Kctd10 (Mmus) 1300003F06Rik Pdip38 mitogenin 1 mitogenin I polymerase delta interacting protein 38 polymerase delta-interacting protein 2 Poldip2 (Mmus) OG9 OG9 homeobox Og9x homeobox OG-9 homeobox protein SEBOX skin-, embryo-, brain- and oocyte-specific homeobox Sebox (Mmus) 0610009H04Rik AU015496 intraflagellar transport 20 homolog intraflagellar transport protein 20 homolog mIFT20 uterine protein Ift20 (Mmus) AI747156 Col6a-1 collagen alpha-1(VI) chain procollagen, type VI, alpha 1 Col6a1 (Mmus) AlphaCP-3 alpha-CP3 poly(rC)-binding protein 3 Pcbp3 (Mmus) AA407335 AI194909 AI265545 LGALS35 Lgals5 gal-9 galectin-9 lectin, galactose binding, soluble 5 Lgals9 (Mmus) 1200013E08Rik A-Raf A-Raf proto-oncogene serine/threonine-protein kinase AW495444 Araf1 proto-oncogene A-Raf raf-related oncogene serine/threonine-protein kinase A-Raf v-raf murine sarcoma 3611 viral oncogene homolog 1 Araf (Mmus) BCFG Pfc complement factor P properdin properdin factor, complement Cfp (Mmus) Clgi EPA TIMP-1 TPA-S1 TPA-induced protein Timp collagenase inhibitor 16C8 fibroblast erythroid-potentiating activity metalloproteinase inhibitor 1 tissue inhibitor of metalloproteinases 1 Timp1 (Mmus) 0910002B17Rik protein UXT ubiquitously expressed transcript protein Uxt (Mmus) Acdp3 Clp3 ancient conserved domain-containing protein 3 mACDP3 metal transporter CNNM3 Cnnm3 (Mmus) A630028F14Rik LMAN2-like protein VIP36-like VIP36-like protein VIPL Lman2l (Mmus) 80 kDa MCM3-associated protein GANP GC-associated DNA primase germinal-center associated nuclear protein minichromosome maintenance deficient 3-associated protein nuclear protein GANP Mcm3ap (Mmus) AW476095 C86676 KEN Pcnt2 kendrin m239Asp m275Asp pericentrin pericentrin 2 pericentrin-250 pericentrin-360 Pcnt (Mmus) formimidoyltransferase-cyclodeaminase glutamate formiminotransferase Ftcd (Mmus) AW122478 Mad Mad1 max dimerization protein 1 max dimerizer 1 Mxd1 (Mmus) 2810049L19Rik Btbd13 DIP DP-interacting protein Gcl Gcl-1 germ cell-less homolog 1 germ cell-less protein-like 1 glc-1 mglc-1 Gmcl1 (Mmus) 2610209M04Rik AI449063 AU022368 Ry1 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein U4/U6.U5 snRNP 27 kDa protein U4/U6.U5 tri-snRNP-associated protein 3 U4/U6.U5-27K putative nucleic acid binding protein RY-1 Snrnp27 (Mmus) 2',5'-oligoadenylate synthetase-like 5 2'-5' oligoadenylate synthetase-like 2 Oasl2 Oasl5 inactive 2'-5' oligoadenylate synthetase 1C Oas1c (Mmus) 2'-5' oligoadenylate synthetase 1H Oas1h (Mmus) 9530014D17Rik BB143339 OCRL1 inositol polyphosphate 5-phosphatase OCRL inositol polyphosphate 5-phosphatase OCRL-1 oculocerebrorenal syndrome of Lowe phosphatidylinositol 3,4,5-triphosphate 5-phosphatase Ocrl (Mmus) AI256814 AI327027 AI461935 AL024000 CaM Calm Cam1 calmodulin-1 Calm1 (Mmus) 1-AGP acyltransferase 3 1-AGPAT 3 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma AW061257 AW493985 D10Jhu12e LPAAT-gamma lpaat3 lysophosphatidic acid acyltransferase 3 lysophosphatidic acid acyltransferase gamma Agpat3 (Mmus) 9030623B18Rik 9130013M11Rik AV376035 Dra chloride anion exchanger down-regulated in adenoma Slc26a3 (Mmus) Sema Seman VIb sema N sema VIB semaZ semaphorin VIB semaphorin-6B semaphorin-N Sema6b (Mmus) AL022808 E3 ubiquitin-protein ligase UHRF1 ICBP90 Np95 RING-type E3 ubiquitin transferase UHRF1 RNF106 mUhrf1 nuclear protein 95 nuclear zinc finger protein Np95 ubiquitin-like PHD and RING finger domain-containing protein 1 ubiquitin-like-containing PHD and RING finger domains protein 1 Uhrf1 (Mmus) 6430584G11Rik A330078I11 DP9 DPLP9 DPP IX DPRP2 dipeptidyl peptidase 9 dipeptidyl peptidase IX dipeptidyl peptidase-like protein 9 Dpp9 (Mmus) receptor activity-modifying protein 2 Ramp2 (Mmus) ILDR3 Lisch7 angulin-3 lipolysis stimulated receptor lipolysis-stimulated lipoprotein receptor liver-specific bHLH-Zip transcription factor liver-specific gene on mouse chromosome 7 protein Lsr (Mmus) 1300003M23Rik AI415002 AW547240 D7Bwg0611e GRAM domain-containing protein 1A protein Aster-A Gramd1a (Mmus) Hlb320 serine protease hepsin Hpn (Mmus) GABA(A) receptor subunit gamma-1 GabaA GabaA/BZ gamma-aminobutyric acid receptor subunit gamma-1 Gabrg1 (Mmus) B-CK Bck CPK-B Ck-3 Ck3 Ckbb creatine kinase B chain creatine kinase B-type creatine phosphokinase B-type Ckb (Mmus) 1110003E12Rik AA450830 AI845540 Sp1-1 specificity protein 1 transcription factor Sp1 Sp1 (Mmus) Ly69 M290 IEL antigen integrin beta-7 integrin beta-P Itgb7 (Mmus) 0610023A07Rik 2810433J21Rik 5830429P19Rik AI325965 Gamm1 MYG1 exonuclease UPF0160 protein MYG1, mitochondrial protein Gamm1 Myg1 (Mmus) Nr1b3 RAR gamma 2 RAR-gamma RARD RARgamma2 nuclear receptor subfamily 1 group B member 3 retinoic acid receptor gamma retinoic acid receptor gamma 4 Rarg (Mmus) 1190001O17Rik 1700010A06Rik C-myc-binding protein Mm-1 D15Ertd697e EIG-1 Eig1 MM-1 c-myc binding protein MM-1 myc modulator 1 prefoldin subunit 5 Pfdn5 (Mmus) ELF-2 EPH-related receptor tyrosine kinase ligand 5 Epl5 Eplg5 HTK ligand Htk-L LERK-5 Lerk5 NLERK-1 ephrin-B2 Efnb2 (Mmus) 2810430M08Rik 5430437H21Rik RRP15-like protein ribosomal RNA-processing protein 15 Rrp15 (Mmus) Arhn Rohn aplysia ras-related homolog N (RhoN) ras homolog N (RhoN) ras homolog gene family, member N rho-related GTP-binding protein Rho7 rho-related GTP-binding protein RhoN rho7 Rnd2 (Mmus) D-serine ammonia-lyase D-serine dehydratase L-serine ammonia-lyase L-serine dehydratase M100034 Rgsc34 Srs serine racemase Srr (Mmus) 1110057H03Rik SNIP4 syncoilin syncoilin intermediate filament 1 syncoilin-1 Sync (Mmus) 1500001L03Rik AI836596 C87088 PeP Pxp fibronectin type III domain-containing protein 5 fibronectin type III repeat-containing protein 2 peroxisomal protein Fndc5 (Mmus) TR-AP TRACP TRAP acid phosphatase type V tartrate-resistant acid ATPase tartrate-resistant acid phosphatase type 5 trATPase type 5 acid phosphatase Acp5 (Mmus) CN CnnI basic calponin calponin H1, smooth muscle calponin-1 Cnn1 (Mmus) 9030401P18Rik AA986398 F-box only protein 9 Fbxo9 (Mmus) 1700034M03Rik 8430415E05Rik BLM C87205 Ccdc132 EARP/GARPII complex subunit VPS50 bcl2-like protein blm coiled-coil domain containing 132 coiled-coil domain-containing protein 132 mKIAA1861 syndetin Vps50 (Mmus) Hars1 MMHRS hisRS histidine tRNA ligase histidine--tRNA ligase, cytoplasmic histidyl-tRNA synthetase, cytoplasmic Hars (Mmus) 2610510D14Rik 2900082I05Rik zinc finger matrin-type protein 2 Zmat2 (Mmus) (E3-independent) E2 ubiquitin-conjugating enzyme C 1110015A16Rik D2Ertd695e E2 ubiquitin-conjugating enzyme C ubcH10 ubiquitin carrier protein C ubiquitin-conjugating enzyme E2 C ubiquitin-protein ligase C Ube2c (Mmus) BC024683 EST1-like protein B LPTS-RP1 LPTS-interacting protein Smg-5 homolog, nonsense mediated mRNA decay factor mKIAA1089 nonsense-mediated mRNA decay factor SMG5 protein SMG5 Smg5 (Mmus) AL024092 CCT-gamma Cctg T-complex protein 1 subunit gamma TCP-1-gamma Tcp1-rs3 TriC-P5 chaperonin subunit 3 (gamma) matricin Cct3 (Mmus) 0610031J06Rik AB027141 NCU-G1 glycosylated lysosomal membrane protein lysosomal protein NCU-G1 Glmp (Mmus) C80750 myocyte-specific enhancer factor 2D Mef2d (Mmus) 2310042N02Rik 2310074C17Rik Matt ma mattrin transmembrane protein 79 Tmem79 (Mmus) 100 kDa coactivator AL033314 Tudor-SN p100 co-activator staphylococcal nuclease domain-containing protein 1 Snd1 (Mmus) alpha-1(XVIII) collagen collagen alpha-1(XVIII) chain endostatin procollagen, type XVIII, alpha 1 Col18a1 (Mmus) AI323572 IFC-1 RFC RFC-1 RFC1 folate transporter 1 intestinal folate carrier 1 intestinal folate carrier protein reduced folate carrier 1 reduced folate transporter solute carrier family 19 (sodium/hydrogen exchanger), member 1 solute carrier family 19 member 1 Slc19a1 (Mmus) AA409963 IPOB Impnb PTAC97 SCG importin beta importin subunit beta-1 karyopherin subunit beta-1 nuclear factor p97 pore targeting complex 97 kDa subunit Kpnb1 (Mmus) AAP-S MP100 Psa R74825 cytosol alanyl aminopeptidase goku puromycin-sensitive aminopeptidase Npepps (Mmus) T-box protein 21 T-box transcription factor TBX21 T-cell-specific T-box transcription factor T-bet TBT1 Tbet Tblym transcription factor TBLYM Tbx21 (Mmus) 0610040E02Rik 39S ribosomal protein L10, mitochondrial C78440 L10mt MRP-L8 Rpml8 Mrpl10 (Mmus) AI426508 CYPLI Cyp51a1 Ldm P450-14DM P450LI cytochrome P450 51A1 cytochrome P450, 51 cytochrome P450-14DM cytochrome P45014DM cytochrome P450LI lanosterol 14-alpha demethylase sterol 14-alpha demethylase Cyp51 (Mmus) 1100001J13Rik 1810041K11Rik D8Ertd325e Nulp1 mKIAA1049 nuclear localized protein 1 transcription factor 25 Tcf25 (Mmus) 2310057H16Rik BB220206 tubulin beta-6 chain Tubb6 (Mmus) AI449518 D8Ertd713e DEF-8 differentially expressed in FDCP 8 Def8 (Mmus) AI385561 D330041M02Rik Mox-1 Mox1 homeobox protein MOX-1 Meox1 (Mmus) 5430411E23Rik sclerostin Sost (Mmus) AV026640 Nkx2.1 T/EBP Titf1 Ttf-1 homeobox protein Nkx-2.1 thyroid nuclear factor 1 thyroid transcription factor 1 thyroid-specific enhancer-binding protein tinman Nkx2-1 (Mmus) Pax-9 paired box gene 9 paired box protein Pax-9 Pax9 (Mmus) Iroquois related homeobox 2 homeodomain protein IRXA2 iroquois homeobox protein 2 iroquois-class homeodomain protein IRX-2 Irx2 (Mmus) Col1a-1 Cola-1 Cola1 Mov-13 Mov13 alpha-1 type 1 collagen alpha-1 type I collagen collagen alpha-1(I) chain procollagen, type I, alpha 1 Col1a1 (Mmus) AA407068 CD49 antigen-like family member C CD49C GAPB3 VLA-3 receptor, alpha 3 subunit galactoprotein B3 integrin alpha-3 Itga3 (Mmus) 50 kDa dystrophin-associated glycoprotein 50DAG Asg adhalin alpha-SG alpha-sarcoglycan Sgca (Mmus) AV237891 DII C Dlx-3 homeobox protein DLX-3 Dlx3 (Mmus) AA408308 AW554517 BB238854 Fkh16 Foxm1b HFH-11B MPHOSPH2 Mpm2 WIN forkhead box protein M1 forkhead homolog 16 trident winged-helix transcription factor Trident Foxm1 (Mmus) 2700050P07Rik AI646725 KICSTOR complex protein ITFG2 integrin-alpha FG-GAP repeat-containing protein 2 Itfg2 (Mmus) AW491344 NIX1 neuronal interacting factor 1 neuronal-interacting factor X 1 nuclear receptor-interacting protein 2 Nrip2 (Mmus) 2310022L06Rik AI316887 tubby-related protein 3 Tulp3 (Mmus) AW545633 BTF2 p52 TFIIH basal transcription factor complex p52 subunit basic transcription factor 2 52 kDa subunit general transcription factor IIH subunit 4 p52 Gtf2h4 (Mmus) AA408537 AI596182 B130022C14Rik M(beta)5 tubulin beta-5 chain Tubb5 (Mmus) ELL-related RNA polymerase II, elongation factor RNA polymerase II elongation factor ELL2 eleven-nineteen lysine-rich leukemia gene 2 elongation factor RNA polymerase II 2 Ell2 (Mmus) Ctnng D930025P04Rik PG desmoplakin III desmoplakin-3 gamma-catenin junction plakoglobin Jup (Mmus) 65 kDa FK506-binding protein 65 kDa FKBP AI325255 FK506 binding protein 6 (65 kDa) FKBP-10 FKBP-65 FKBP65 Fkbp-rs1 Fkbp1-rs Fkbp6 Fkbprp PPIase FKBP10 immunophilin FKBP65 peptidyl-prolyl cis-trans isomerase FKBP10 rotamase Fkbp10 (Mmus) 4921517C11Rik kelch-like protein 10 Klhl10 (Mmus) HB9 Hlxb9 MNR2 homeobox gene HB9 homeobox protein HB9 motor neuron and pancreas homeobox protein 1 Mnx1 (Mmus) D5Kng1 Gm1040 SGD1 homolog nucleolar MIF4G domain-containing protein 1 Nom1 (Mmus) 1200007D18Rik ER-Golgi intermediate compartment 32 kDa protein ERGIC-32 endoplasmic reticulum-Golgi intermediate compartment protein 1 maa-136 Ergic1 (Mmus) Kos1 Tnk1a Tnk1b kinase of embryonic stem cells non-receptor tyrosine kinase non-receptor tyrosine-protein kinase TNK1 Tnk1 (Mmus) Centb1 arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 centaurin, beta 1 cnt-b1 Acap1 (Mmus) S-II SII-K1 tissue-specific transcription factor S-II transcription elongation factor A protein 3 transcription elongation factor S-II protein 3 transcription elongation factor TFIIS.h Tcea3 (Mmus) AW208918 CSN10 Csnk kappa-casein Csn3 (Mmus) Ifnl PC4 TPA-induced sequence 7 Tis7 interferon-related developmental regulator 1 nerve growth factor-inducible protein PC4 Ifrd1 (Mmus) 4930473A22Rik Ndr2 Ndr54 nuclear Dbf2-related kinase 2 serine/threonine-protein kinase 38-like Stk38l (Mmus) 4833438B11Rik 4930540D11Rik Brpf2 bromodomain and PHD finger-containing protein 1 peregrin Brpf1 (Mmus) ALR2 AR Ahr-1 Ahr1 Akr1b1 Aldor1 Aldr1 aldehyde reductase 1 aldo-keto reductase family 1 member B1 aldo-keto reductase family 1 member B3 aldo-keto reductase family 1, member B1 (aldose reductase) aldose reductase Akr1b3 (Mmus) N homeobox protein Hox-C13 naked Hoxc13 (Mmus) Hox-3.7 homeo box C11 homeobox protein Hox-3.7 homeobox protein Hox-C11 Hoxc11 (Mmus) Hoxc8 (Mmus) Hox-3.3 Hox-6.1 homeo box C6 homeobox protein Hox-3.3 homeobox protein Hox-6.1 homeobox protein Hox-C6 Hoxc6 (Mmus) AI255817 GST class-theta-1 Gstt1-1 glutathione S-transferase theta-1 Gstt1 (Mmus) AI118089 glutathione S-transferase theta-3 Gstt3 (Mmus) C78655 D-dopachrome decarboxylase Ddt (Mmus) L-tyrosine:2-oxoglutarate aminotransferase tyrosine aminotransferase tyrosine transaminase Tat (Mmus) 1810006A16Rik AI642133 MARVEL domain-containing protein 3 Marvd3 Mrvldc3 Marveld3 (Mmus) 2310005B10Rik ATP-dependent RNA helicase DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DEAD box protein 18 Ddx18 (Mmus) AW108023 HCG MUB membrane-anchored ubiquitin-fold protein mmMUB protein HCG-1 ubiquitin-like protein 3 Ubl3 (Mmus) 9030613F08Rik 9130427A09Rik AW061306 GRAM domain-containing protein 2B GRAM domain-containing protein 3 Gramd2b HCV NS3-transactivated protein 2 NS3TP2 Gramd3 (Mmus) 1110003A02Rik AIMP3 elongation factor p18 eukaryotic translation elongation factor 1 epsilon-1 multisynthase complex auxiliary component p18 multisynthetase complex auxiliary component p18 Eef1e1 (Mmus) AKT1 kinase Akt Akt1m protein LTR-akt PKB PKB alpha PKB/Akt PKBalpha RAC-PK-alpha RAC-alpha serine/threonine-protein kinase Rac protein kinase B-alpha proto-oncogene c-AKT related to A and C kinases tumor rejection antigen peptide pRLib Akt1 (Mmus) 2210009B08Rik BB107105 claudin-15 Cldn15 (Mmus) mKIAA4048 pro-interleukin-16 Il16 (Mmus) ATP6N1C ATP6a3 ATPase, H+ transporting, lysosomal I Atp6i OC-116 OPTB1 Stv1 TIRC7 V-ATPase a3 V-type proton ATPase 116 kDa subunit a3 Vph1 oc osteosclerotic Tcirg1 (Mmus) N-acetyl-glucosaminidase alpha-N-acetylglucosaminidase alpha-N-acetylglucosaminidase, lysosomal Naglu (Mmus) 1300003G02Rik 4'-phosphopantetheine adenylyltransferase and dephospho-CoA kinase CoA synthase Dpck Ppat Ukr1 bifunctional coenzyme A synthase Coasy (Mmus) E130215L21Rik Smoh bent body bnb smoothened smoothened homolog Smo (Mmus) 1300010A20Rik Pen penumbra proerythroblast new membrane tetraspanin-33 Tspan33 (Mmus) 1200013P10Rik 5730590A01Rik C80326 Crn, crooked neck-like 1 crn crooked neck homolog crooked neck-like protein 1 Crnkl1 (Mmus) 2010003K16Rik 4632403N06Rik AW821980 RASSF4 ras and Rab interactor 2 ras interaction/interference protein 2 Rin2 (Mmus) FGCP GCP2 GCPII N-acetylated-alpha-linked acidic dipeptidase I NAALADase I folylpoly-gamma-glutamate carboxypeptidase glutamate carboxypeptidase 2 glutamate carboxypeptidase II mGCP membrane glutamate carboxypeptidase mopsm prostate-specific membrane antigen homolog pteroylpoly-gamma-glutamate carboxypeptidase Folh1 (Mmus) 1110001O09Rik AA409036 CHORD domain-containing protein 1 CHORD-containing protein 1 Chp-1 cysteine and histidine-rich domain-containing protein 1 morgana protein morgana Chordc1 (Mmus) 3'-phosphate/5'-hydroxy nucleic acid ligase AI255213 AI463255 D10Wsu52e FAAP HSPC117 RNA-splicing ligase RtcB homolog focal adhesion-associated protein tRNA-splicing ligase RtcB homolog Rtcb (Mmus) 2310058A11Rik 2610205J09Rik AI098170 AL022879 AV083409 AW550690 periodic tryptophan protein 1 homolog Pwp1 (Mmus) 2410015K21Rik A230052G17Rik AI117679 AW260462 C85118 F-box only protein 7 Fbxo7 (Mmus) CANP small subunit Capa-4 Capa4 Capn4 Cdps Css1 D7Ertd146e calcium-activated neutral proteinase small subunit calcium-dependent protease small subunit 1 calpain 4 calpain regulatory subunit calpain small subunit 1 Capns1 (Mmus) low-density lipoprotein receptor-related protein 3 Lrp3 (Mmus) CDHF13 desmoglein-4 lah Dsg4 (Mmus) Evx-2 even skipped homeotic gene 2 homolog homeobox even-skipped homolog protein 2 Evx2 (Mmus) Hox-4.8 homeo box D13 homeobox protein Hox-4.8 homeobox protein Hox-D13 spdh Hoxd13 (Mmus) Hox-4.7 Hox-5.6 homeo box D12 homeobox protein Hox-4.7 homeobox protein Hox-5.6 homeobox protein Hox-D12 Hoxd12 (Mmus) FBP1 FR-alpha Folbp-1 Folbp1 folate receptor alpha folate-binding protein 1 Folr1 (Mmus) AL118244 ClpB caseinolytic peptidase B homolog Skd3 caseinolytic peptidase B protein homolog suppressor of K+ transport defect 3 suppressor of potassium transport defect 3 Clpb (Mmus) CDC10 protein homolog Cdc10 E430034N22 Sept7 cell division cycle 10 homolog septin-7 Sept7 (Mmus) 1810021D01Rik 2900029I10Rik DHHC-4 palmitoyltransferase ZDHHC4 probable palmitoyltransferase ZDHHC4 zinc finger DHHC domain-containing protein 4 Zdhhc4 (Mmus) AL023026 D5Ertd559e RAS-related C3 botulinum substrate 1 p21-Rac1 ras-related C3 botulinum toxin substrate 1 Rac1 (Mmus) 214 kDa nucleoporin BC039282 CAN D2H9S46E nuclear pore complex protein Nup214 nucleoporin Nup214 Nup214 (Mmus) 2810003C17Rik AI043124 C87647 Iba2 allograft inflammatory factor 1-like ionized calcium binding adapter molecule 2 Aif1l (Mmus) MC-CPA mast cell carboxypeptidase A Cpa3 (Mmus) 9430031G15Rik 9830146M04 Ltbp-1 Ltbp1L TGF-beta1-BP-1 Tgfb b2b1000Clo latent TGF beta binding protein latent transforming growth factor beta binding protein 1L latent-transforming growth factor beta-binding protein 1 transforming growth factor beta-1-binding protein 1 Ltbp1 (Mmus) UDPGP UGPase UTP--glucose-1-phosphate uridylyltransferase uridindiphosphoglucosepyrophosphorylase 2 Ugp2 (Mmus) m-erg2 potassium voltage-gated channel subfamily H member 6 Kcnh6 (Mmus) 6720406L13Rik 6720477L24 D8Ertd812e TRM1 tRNA methyltransferase 1 homolog n(2),N(2)-dimethylguanosine tRNA methyltransferase tRNA (guanine(26)-N(2))-dimethyltransferase tRNA 2,2-dimethylguanosine-26 methyltransferase tRNA(guanine-26,N(2)-N(2)) methyltransferase tRNA(m(2,2)G26)dimethyltransferase Trmt1 (Mmus) 2010001H03Rik 4930511N13Rik BTB (POZ) domain containing 14B BTB/POZ domain-containing protein 14B Btbd14b NAC-1 Nac1 nucleus accumbens-associated protein 1 transcriptional repressor NAC1 Nacc1 (Mmus) CCAAT-box-binding transcription factor CTF NF-I/X NF1-X NFI-X TGGCA-binding protein nuclear factor 1 X-type nuclear factor 1/X Nfix (Mmus) AAAT ASC-like Na(+)-dependent neutral amino acid transporter ASCT2 ASCT2 ATB(0) ATBO M7V1 M7VS1 R16 RDRC Slc1a7 insulin-activated amino acid transporter neutral amino acid transporter B(0) sodium-dependent neutral amino acid transporter type 2 solute carrier family 1 member 5 solute carrier family 1, member 7 Slc1a5 (Mmus) A1S9 Sbx Ube-1 Ube1x ubiquitin-activating enzyme E1, Chr X ubiquitin-like modifier-activating enzyme 1 Uba1 (Mmus) 6820430P06Rik AI551257 B130011O06Rik C630030D09 F8VWF VWD Von Willebrand factor homolog von Willebrand factor Vwf (Mmus) LSE Ysg2 clone 165 sialate O-acetylesterase sialic acid-specific 9-O-acetylesterase yolk sac gene 2 yolk sac protein 2 Siae (Mmus) 1190004B15Rik 2210413P10Rik AU040484 CT-like protein CTM CTX Ctm V-set and immunoglobulin domain-containing protein 2 cortical thymocyte receptor (X. laevis CTX) like cortical thymocyte-like protein Vsig2 (Mmus) 2310008D05Rik Esam1 W117m endothelial cell-selective adhesion molecule Esam (Mmus) Sp17 band 34 sperm protein 17 sperm surface protein Sp17 Spa17 (Mmus) D0HXS9928E XAP-5 protein FAM50A protein XAP-5 Fam50a (Mmus) AW550900 Sta emerin Emd (Mmus) Taco1 (Mmus) 9630027E11 GluK3 GluR7-3 Glur-7 Glur7 glutamate receptor 7 glutamate receptor ionotropic, kainate 3 Grik3 (Mmus) 2900064I19Rik AMPA-selective glutamate receptor 3 GluA3 GluR-C GluR-K3 Glur-3 Glur3 Gluralpha3 glutamate receptor 3 glutamate receptor channel alpha3 subunit Gria3 (Mmus) MOP5 bHLHe11 neuronal PAS domain-containing protein 1 neuronal PAS1 Npas1 (Mmus) BC058408 SIPA1-like protein 2 mKIAA1389 signal-induced proliferation-associated 1-like protein 2 Sipa1l2 (Mmus) 2310033A20Rik 9930028M04Rik AP-4 adapter complex subunit epsilon AP-4 adaptor complex subunit epsilon AP-4 complex subunit epsilon-1 AV087807 adapter-related protein complex 4 subunit epsilon-1 adaptor-related protein complex 4 subunit epsilon-1 epsilon subunit of AP-4 epsilon-adaptin Ap4e1 (Mmus) 0610006A11Rik 2500001N03Rik BVR A Blvr biliverdin reductase A biliverdin-IX alpha-reductase Blvra (Mmus) B230341P03 D130075J17Rik Kiaa1444-hp LU1 PDZ domain-containing RING finger protein 4-like protein PDZ domain-containing protein 4 PDZRN4L Pdzk4 Pdzrnk4l Xlu Pdzd4 (Mmus) Mssk1 SR-protein-specific kinase 3 SRSF protein kinase 3 Stk23 muscle-specific serine kinase 1 serine/threonine kinase 23, muscle-specific serine kinase 1 70 serine/threonine-protein kinase 23 serine/threonine-protein kinase SRPK3 Srpk3 (Mmus) NAD(+)-specific ICDH subunit gamma isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial isocitric dehydrogenase subunit gamma Idh3g (Mmus) Bstk3 CaMKIbeta2 CaMKlb2 Camk1b Punc caM kinase I beta caM kinase IB caM-KI beta caMKI-beta caMKlb1 calcium/calmodulin-dependent protein kinase 1, beta calcium/calmodulin-dependent protein kinase type 1B pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog Pnck (Mmus) AW743063 C78062 SSR-delta TRAP-delta Trap signal sequence receptor subunit delta translocon-associated protein subunit delta Ssr4 (Mmus) B-cell receptor-associated protein 31 BCR-associated protein 31 Bap31 accessory protein BAP31 p28 Bcap31 (Mmus) 2810405J04Rik AL024114 protein FAM98A Fam98a (Mmus) AW208642 LTBP-2 latent-transforming growth factor beta-binding protein 2 Ltbp2 (Mmus) 6430520K01 ALL-1 All1 Cxxc7 HRX HTRX1 Mll Mll1 cysteine methyltransferase KMT2A histone-lysine N-methyltransferase 2A histone-lysine N-methyltransferase MLL mKIAA4050 myeloid/lymphoid or mixed-lineage leukemia protein 1 trithorax Drosophila zinc finger protein HRX Kmt2a (Mmus) 1500035H01Rik AA408110 AI663846 R75047 c11orf2 intraflagellar transport 46 homolog intraflagellar transport protein 46 homolog Ift46 (Mmus) 0610039J01Rik AI429491 transmembrane protein 25 Tmem25 (Mmus) Ctg-3 Ctg3 T-cell receptor T3 gamma chain T-cell surface glycoprotein CD3 gamma chain T3g Cd3g (Mmus) 1810073E21Rik 4930519D19Rik AI480686 TRAPP complex subunit 6A TRS33 mhyp trafficking protein particle complex subunit 6A Trappc6a (Mmus) 5131400N11Rik AI132449 SPT6 Supt6h mKIAA0162 suppressor of Ty 6 homolog transcription elongation factor SPT6 Supt6 (Mmus) AI874642 D11Bhm180e Deepest MAP126 Mastrin S17 astrin microtubule-associated protein mitotic spindle-associated protein p126 sperm-associated antigen 5 Spag5 (Mmus) D11Bhm185e Fkh19 HFH-11 HNF-3/forkhead homolog 11 Hfh11 Whn forkhead box protein N1 hepatocyte nuclear factor 3 forkhead homolog 11 nu nude winged-helix transcription factor nude Foxn1 (Mmus) D11Bhm52 HRG4 MRG4 Rg4 Rtg4 Unc119h protein unc-119 homolog A retinal gene 4 retinal protein 4 Unc119 (Mmus) AI326479 Narr RAB34, member of RAS oncogene family Rah Rah1 rab-39 ras-related homolog ras-related protein Rab-34 ras-related protein Rab-39 ras-related protein Rah Rab34 (Mmus) AI853825 stromal cell-derived factor 2 Sdf2 (Mmus) AW538188 CycE1 G1/S-specific cyclin-E1 Ccne1 (Mmus) 4932437G14Rik Meilb2 heat shock factor 2-binding protein meiotic localizer of BRCA2 Hsf2bp (Mmus) BH3-only Bcl-2 binding component 3 PUMA PUMA/JFY1 bcl-2-binding component 3 p53 up-regulated modulator of apoptosis Bbc3 (Mmus) cardiac C-protein cardiac MyBP-C myosin-binding protein C, cardiac-type Mybpc3 (Mmus) 26S protease regulatory subunit 6A 26S proteasome AAA-ATPase subunit RPT5 26S proteasome regulatory subunit 6A TAT-binding protein 1 TBP-1 Tat binding protein 1 proteasome 26S subunit ATPase 3 Psmc3 (Mmus) Acp-2 LAP lysosomal acid phosphatase Acp2 (Mmus) 43 kDa postsynaptic protein 43 kDa receptor-associated protein of the synapse 43kDa 43kDa acetylcholine receptor-associated protein Nraps Raps acetylcholine receptor-associated 43 kDa protein rapsyn receptor-associated protein of the synapse, 43 kDa Rapsn (Mmus) 1100001L14Rik AA387663 ZIP-13 ZIP13 solute carrier family 39 member 13 zinc transporter ZIP13 zrt- and Irt-like protein 13 Slc39a13 (Mmus) B230218O03 B230345P09Rik C88023 CELF-2 CUG triplet repeat, RNA binding protein 2 CUG-BP- and ETR-3-like factor 2 CUG-BP2 CUGBP Elav-like family member 2 Cugbp2 D230046B21Rik Etr-3 Napor Napor-2 RNA-binding protein BRUNOL-3 bruno-like protein 3 elav-type RNA-binding protein 3 mETR-3 mNapor neuroblastoma apoptosis-related RNA-binding protein Celf2 (Mmus) AU018371 LXR LXR alpha RLD1 Unr1 liver X receptor alpha oxysterols receptor LXR-alpha ubiquitously-expressed nuclear receptor 1 Nr1h3 (Mmus) 2610043A19Rik DNA damage-binding protein 2 Ddb2 (Mmus) 31 kDa-transforming protein Dis-1 Dis1 PU.1 SFFV proviral integration 1 protein Sfpi-1 Sfpi1 Spi-1 Tcfpu1 Tfpu.1 hematopoietic transcription factor PU.1 transcription factor PU.1 Spi1 (Mmus) 1200014H24Rik 5930416L09Rik AI159724 SF3a120 splicing factor 3 subunit 1 splicing factor 3A subunit 1 Sf3a1 (Mmus) signal transducer and transcription activator 6 Stat6 (Mmus) 4930459O04Rik A2/6 AI528775 Cln MEG 1 antigen calmegin calnexin-T Clgn (Mmus) KAP KDAP-1 Kdap NAP1 SNAPA kidney-derived aspartic protease-like protein napsin-A pronapsin Napsa (Mmus) AI428238 inactive serine/threonine-protein kinase VRK3 serine/threonine-protein kinase VRK3 serine/threonine-protein pseudokinase VRK3 Vrk3 (Mmus) 1500002O20Rik AI429693 N28092 nonsense-mediated mRNA decay factor SMG9 protein SMG9 protein smg-9 homolog smg-9 homolog, nonsense mediated mRNA decay factor Smg9 (Mmus) D5Ertd149e PAX transactivation activation domain-interacting protein PAX-interacting protein 1 PTIP Paxip1 (Mmus) 1110007A06Rik AJ237586 AW125795 E3 ubiquitin-protein ligase RMND5A Gid2 MTA.D02.090 protein RMD5 homolog A Rmnd5a (Mmus) C77703 Mov-10 moloney leukemia virus 10 protein putative helicase MOV-10 Mov10 (Mmus) 2310008J22Rik PP2C-zeta PP2Czeta Ppp2cz protein phosphatase 1J protein phosphatase 2C zeta Ppm1j (Mmus) AI324259 Arh9 Arhc SIG-61 aplysia ras-related homolog 9 (RhoC) ras homolog 9 (RhoC) ras homolog gene family, member C rho-related GTP-binding protein RhoC silica-induced gene 61 protein Rhoc (Mmus) 4930432K09Rik proline-rich protein 27 Prr27 (Mmus) DTEF-1 ETF-related factor 1 ETFR-1 TEAD-3 TEF-5 Tcf13r2 transcriptional enhancer factor TEF-5 Tead3 (Mmus) NUC-1 NUC1 Nr1c2 PPAR-beta PPAR-delta PPAR[b] PPARdelta PPARdelta/beta Peroxisome proliferator-activated receptor beta Pparb Pparb/d nuclear hormone receptor 1 nuclear receptor subfamily 1 group C member 2 peroxisome proliferator-activated receptor delta Ppard (Mmus) 2410003F05Rik 6430538D02Rik AV094905 DEF-6 IRF-4-binding protein IRF4-binding protein Ibp SWAP-70-like adapter of T-cells Slat Slat2 Slat6 differentially expressed in FDCP 6 Def6 (Mmus) AL022617 ASF-1 End4 Gcap4 Pw1 Zfp102 granule cell antiserum positive 4 mKIAA0287 paternally expressed gene 3 paternally-expressed gene 3 protein Peg3 (Mmus) zinc finger, imprinted 1 Zim1 (Mmus) 1810034B16Rik EyeLinc16 Hyrac hypoxia/reoxygenation regulatory factor in astrocytes meteorin Metrn (Mmus) 2400010G15Rik AW822050 Tmem112 cld lipase maturation factor 1 transmembrane protein 112 Lmf1 (Mmus) 9030612I22Rik AI504405 IOP1 Narfl PRN cytosolic Fe-S cluster assembly factor NARFL cytosolic iron-sulfur assembly component 3 iron-only hydrogenase-like protein 1 nuclear prelamin A recognition factor-like protein Narfl (Mmus) 425O18-1 Arp4 Bk89 Fiaf Hfarp Ng27 Pgar Pgarg Pp1158 angiopoietin-like protein 4 angiopoietin-related protein 4 fasting-induced adipose factor fibrinogen/angiopoietin-related protein hepatic fibrinogen/angiopoietin-related protein major histocompatibility complex region NG27 secreted protein Bk89 Angptl4 (Mmus) AA545217 Ask DBF4 homolog activator of S phase kinase protein DBF4 homolog A Dbf4 (Mmus) death domain-associated protein 6 death-domain associated protein Daxx (Mmus) 425O18-1 8D6 CD320 antigen D17Ertd716e NG29 TCblR VLDL putative VLDL lipoprotein receptor transcobalamin receptor Cd320 (Mmus) 8430408O15Rik AA409693 Imp4a RanBP4 imp4 importin 4a importin-4 ran-binding protein 4 Ipo4 (Mmus) 1200014D02Rik AI893436 MP70 transmembrane 9 superfamily member 1 Tm9sf1 (Mmus) REC8-like 1 Rec8L1 cohesin Rec8p meiotic cohesion Rec8 meiotic recombination protein REC8 homolog mrec Rec8 (Mmus) IFN-alpha-responsive transcription factor subunit ISGF-3 gamma ISGF3 p48 subunit Irf-9 Isgf3g interferon dependent positive acting transcription factor 3 gamma interferon regulatory factor 9 interferon-stimulated gene factor 3 gamma p48 transcriptional regulator ISGF3 subunit gamma Irf9 (Mmus) 1810008P16Rik 5730544D12Rik AA959850 GMP reductase 2 GMPR 2 guanosine 5'-monophosphate oxidoreductase 2 Gmpr2 (Mmus) 1810034K20Rik AI035604 MDP-1 magnesium-dependent phosphatase 1 Mdp1 (Mmus) 1110029G07Rik AW112170 D14Ertd484e dehydrogenase/reductase SDR family member 1 short chain dehydrogenase/reductase family 19C member 1 Dhrs1 (Mmus) C230035B04 Cspg3 Cspg3-rs TGFbeta-induced transcript, brain Tgfbit chondroitin sulfate proteoglycan 3, related sequence neurocan core protein Ncan (Mmus) AI428876 BB161850 BC021367 transmembrane protein 161A Tmem161a (Mmus) 2410153K17Rik AW554412 armadillo repeat-containing protein 6 Armc6 (Mmus) 2310045N01Rik BLOC-1-related complex subunit 8 MEF2B neighbor gene protein homolog Mef2bnb protein MEF2BNB Borcs8 (Mmus) 2900084M01Rik mitochondrial coenzyme A transporter SLC25A42 Slc25a42 (Mmus) 2700073N08Rik SDP1 SH3PX1 sorting nexin-9 Snx9 (Mmus) 2610024N24Rik AA408221 ran-binding protein 3 Ranbp3 (Mmus) 2010012C24Rik AV006275 B14.7 CI-B14.7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH-ubiquinone oxidoreductase subunit B14.7 complex I-B14.7 Ndufa11 (Mmus) Op3 bone morphogenetic protein 8B Bmp8b (Mmus) AV090102 COUP transcription factor 3 COUP-TF3 EAR-2 EAR2 Erbal2 V-erbA-related protein 2 avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2 nuclear receptor subfamily 2 group F member 6 Nr2f6 (Mmus) 2010315L10Rik 5730403H22Rik AV002165 D12 Ed2 Q-snare USE1-like protein embryonic development factor 2 p31 vesicle transport protein USE1 Use1 (Mmus) 9430098E02Rik AI326022 AI593544 occludin/ELL domain-containing protein 1 Ocel1 (Mmus) Mirk dual specificity tyrosine-phosphorylation-regulated kinase 1B Dyrk1b (Mmus) 9930012E13Rik AA120551 AA387315 AA473386 B-Raf proto-oncogene serine/threonine-protein kinase (p94) B-raf Braf-2 Braf2 C230098H17 C87398 D6Ertd631e proto-oncogene B-Raf serine/threonine-protein kinase B-raf Braf (Mmus) 1810011O01Rik 8kDa AGGG AI325567 CI-AGGG NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH-ubiquinone oxidoreductase AGGG subunit complex I-AGGG Ndufb2 (Mmus) AF010600 BC057116 P113 RING-type E3 ubiquitin transferase HLTF SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 Smarca3 Snf2l3 TNF-response element-binding protein helicase-like transcription factor sucrose nonfermenting protein 2-like 3 Hltf (Mmus) 1190003A07Rik 2610031L17Rik ANT-1 PRP6 homolog PRP6 pre-mRNA splicing factor 6 homolog U5 snRNP-associated 102 kDa protein U5-102 kDa protein U5-102K pre-mRNA-processing factor 6 Prpf6 (Mmus) 2610042F04Rik AI324841 AW547781 G-alpha interacting protein GAIP regulator of G-protein signaling 19 Rgs19 (Mmus) 2900073E09Rik Rgsz1 regulator of G-protein signaling 20 regulator of G-protein signaling Z1 Rgs20 (Mmus) AA675331 LABH3 abhydrolase domain-containing protein 3 lung alpha/beta hydrolase 3 mmLABH3 phospholipase ABHD3 Abhd3 (Mmus) AA407109 AL023031 SMD1 sm-D autoantigen sm-D1 small nuclear ribonucleoprotein Sm D1 snRNP core protein D1 Snrpd1 (Mmus) A930031F18Rik AV279199 mitochondrial protein with oncostatic activity mitostatin trichoplein keratin filament-binding protein Tchp (Mmus) AI847750 D16Ium10 D16Ium10e T-lymphoma invasion and metastasis-inducing protein 1 TIAM-1 rho guanine nucleotide exchange factor TIAM1 Tiam1 (Mmus) Nafld Tcs2 tuberin tuberous sclerosis 2 protein homolog Tsc2 (Mmus) 1110057H16Rik 60S ribosomal protein L3-like ribosomal protein L3 pseudogene Rpl3l (Mmus) 0610011L07Rik 1200011K07Rik 2010007A20Rik E3karp NHE3 kinase A regulatory protein E3KARP NHERF-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 Nherf2 Octs2 SRY-interacting protein 1 Sip-1 Sip1 Sryip1 Tka-1 sodium-hydrogen exchanger regulatory factor 2 tyrosine kinase activator protein 1 Slc9a3r2 (Mmus) 2410104I19Rik 2810454F19Rik 60 kDa poly(U)-binding-splicing factor SIAHBP1 fuse-binding protein-interacting repressor poly(U)-binding-splicing factor PUF60 Puf60 (Mmus) 130 kDa cis-Golgi matrix protein AW555139 GM130 SY11 protein golgin subfamily A member 2 golgin-95 Golga2 (Mmus) UCK 1 URK1 Umpk cytidine monophosphokinase 1 uridine monophosphate kinase uridine monophosphokinase 1 uridine-cytidine kinase 1 Uck1 (Mmus) AW545522 adseverin gelsolin-like protein scinderin Scin (Mmus) A630026H08Rik Eos Zfpn1a4 Znfn1a4 ikaros family zinc finger protein 4 zinc finger protein Eos zinc finger protein, subfamily 1A, 4 (Eos) Ikzf4 (Mmus) 1810046J19Rik AI463380 Rdx12 migration and invasion enhancer 1 protein C17orf37 homolog Mien1 (Mmus) A-esterase 1 PON 1 Pon aromatic esterase 1 serum aryldialkylphosphatase 1 serum paraoxonase/arylesterase 1 Pon1 (Mmus) AI323647 Ark Tyro7 Ufo adhesion-related kinase tyrosine-protein kinase receptor UFO ufo oncogene homolog Axl (Mmus) TGF-beta1 TGFbeta1 Tgfb Tgfb-1 transforming growth factor beta-1 proprotein Tgfb1 (Mmus) 1200014H14Rik 2810446P04Rik AA545218 D7Ertd462e coiled-coil domain-containing protein 97 Ccdc97 (Mmus) CTfin12 NTfin12 Zfp-40 zinc finger protein 40 Zfp40 (Mmus) A-kinase anchor protein 8-like AKAP8-like protein HAP95 Nakap95 neighbor of A-kinase anchoring protein 95 neighbor of AKAP95 Akap8l (Mmus) 9530036O11Rik Dsh HHG-1 Hhg1 Hx Hxl3 M100081 ShhNC hemimelic extra toes shh unprocessed N-terminal signaling and C-terminal autoprocessing domains short digits sonic hedgehog protein Shh (Mmus) 6030457N17Rik programmed cell death protein 2-like Pdcd2l (Mmus) 2810405L04Rik C76800 RAP74 TFIIF-alpha general transcription factor IIF polypeptide 1 (74kD subunit) general transcription factor IIF subunit 1 transcription initiation factor IIF subunit alpha Gtf2f1 (Mmus) ATP-dependent Clp protease proteolytic subunit, mitochondrial AU019820 ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit D17Wsu160e caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog caseinolytic protease, ATP-dependent, proteolytic subunit homolog endopeptidase Clp putative ATP-dependent Clp protease proteolytic subunit, mitochondrial Clpp (Mmus) 2310045B01Rik 2510008E23Rik Abh7 Spata11 alkB, alkylation repair homolog 7 alkylated DNA repair protein alkB homolog 7 alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial probable alpha-ketoglutarate-dependent dioxygenase ABH7 spermatogenesis associated 11 Alkbh7 (Mmus) PSP persephin Pspn (Mmus) 4432409M07Rik DENN domain-containing protein 1C connecdenn 3 Dennd1c (Mmus) 1500012F11Rik AU019660 AV213303 mediator of RNA polymerase II transcription subunit 6 mediator of RNA polymerase II transcription, subunit 6 homolog Med6 (Mmus) PKD PKD1 Pkcm Prkcm nPKC-D1 nPKC-mu protein kinase C mu type protein kinase C, mu protein kinase D serine/threonine-protein kinase D1 Prkd1 (Mmus) AI323664 BB161688 SH2 domain-containing leukocyte protein of 76 kDa SLP-76 SLP-76 tyrosine phosphoprotein SLP76 lymphocyte cytosolic protein 2 m1Khoe twm Lcp2 (Mmus) 2610100P18Rik AA407533 Capts Cas Xpo2 chromosome segregation 1-like protein exp2 exportin-2 importin-alpha re-exporter Cse1l (Mmus) 1500004D14Rik 2900026I01Rik AU041458 D2Ertd186e N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae) N-alpha-acetyltransferase 20 N-terminal acetyltransferase B complex catalytic subunit NAA20 N-terminal acetyltransferase B complex catalytic subunit NAT5 Nat5 methionine N-acetyltransferase natB catalytic subunit natB complex subunit NAT5 Naa20 (Mmus) AV120107 PKR-associated protein X PKR-associating protein X PRK Pact RAX interferon-inducible double-stranded RNA-dependent protein kinase activator A lear protein activator of the interferon-induced protein kinase Prkra (Mmus) 23 kDa FK506-binding protein 23 kDa FKBP 23kDa FKBP-23 FKBP-7 FKBP23 PPIase FKBP7 peptidyl-prolyl cis-trans isomerase FKBP7 rotamase Fkbp7 (Mmus) FAPP-1 FAPP1 PH domain-containing family A member 3 phosphatidylinositol-four-phosphate adapter protein 1 phosphoinositol 4-phosphate adapter protein 1 pleckstrin homology domain-containing family A member 3 Plekha3 (Mmus) 0610042I15Rik 1810013M05Rik AW105923 YKT6 homolog prenylated SNARE protein (Ykt6) synaptobrevin homolog YKT6 Ykt6 (Mmus) C87820 WSTF Wbscr9 Williams-Beuren syndrome chromosome region 9 homolog bromodomain adjacent to zinc finger domain protein 1B bromodomain adjacent to zinc finger domain, 1B; Williams-Beuren syndrome chromosome region 9 homolog tyrosine-protein kinase BAZ1B williams syndrome transcription factor homolog williams-Beuren syndrome chromosomal region 9 protein homolog Baz1b (Mmus) AI132582 D130055I09Rik PAF-2 peroxin-6 peroxisomal-type ATPase 1 peroxisome assembly factor 2 Pex6 (Mmus) 39S ribosomal protein L2, mitochondrial CGI-22 L2mt MRP-L14 MRP-L2 Rpml14 ribosomal protein, mitochondrial, L14 Mrpl2 (Mmus) Mea-1 male-enhanced antigen 1 Mea1 (Mmus) glycine N methyl transferase glycine N-methyltransferase Gnmt (Mmus) GluN2D GluRepsilon4 N-methyl D-aspartate receptor subtype 2D NMDAR2D NR2D glur epsilon 4 glutamate [NMDA] receptor subunit epsilon-4 glutamate receptor ionotropic, NMDA 2D ionotropic NMDA glutamate receptor epsilon 4 subunit type 2 Grin2d (Mmus) 8030486F04Rik AW215843 ER lumen protein-retaining receptor 1 Erd2.1 KDEL endoplasmic reticulum protein retention receptor 1 KDEL receptor 1 Kdelr1 (Mmus) 2310076O21Rik AI481604 transmembrane protein 143 Tmem143 (Mmus) A030007L17Rik AA673177 Gctg Ggc gamma-glutamylcyclotransferase Ggct (Mmus) D12Ggc2e Serh mJagged2-1 protein jagged-2 sm syndactylism Jag2 (Mmus) BTB/POZ domain-containing protein 6 Btbd6 (Mmus) 1110030M18Rik UDPG pyrophosphatase UGPPase nucleoside diphosphate-linked moiety X motif 14 nudix motif 14 uridine diphosphate glucose pyrophosphatase NUDT14 Nudt14 (Mmus) AU040950 AV006210 Epdm2 Epdr2 MERP-1 MERP-2 MERP2 Ucc1 ependymin 2 ependymin related protein 2 mammalian ependymin-related protein 1 upregulated in colorectal cancer gene 1 Epdr1 (Mmus) 3632430F08Rik Fliih cytoskeletal actin-modulating protein flightless I homolog protein flightless-1 homolog Flii (Mmus) DNA topoisomerase 3-alpha DNA topoisomerase III alpha Top IIIa topoisomerase (DNA) 3 alpha topoisomerase 3 alpha Top3a (Mmus) 9830134P12Rik APG4 (ATG4) autophagy-related homolog D APG4-D AUT-like 4, cysteine endopeptidase Apg4d Atg4dl Autl4 autophagin-4 autophagy-related 4D autophagy-related cysteine endopeptidase 4 autophagy-related protein 4 homolog D cysteine protease ATG4D cysteine protease involved in autophagy APG4-D Atg4d (Mmus) 2610028E17Rik Tgt guanine insertion enzyme queuine tRNA-ribosyltransferase 1 queuine tRNA-ribosyltransferase catalytic subunit 1 tRNA-guanine transglycosylase Qtrt1 (Mmus) S3-12 adipocyte protein S3-12 mKIAA1881 perilipin-4 plasma membrane associated protein, S3-12 Plin4 (Mmus) HRP-2 Hdgfrp2 hepatoma-derived growth factor, related protein 2 hepatoma-derived growth factor-related protein 2 Hdgfl2 (Mmus) AL023013 AL024058 CAF-1 CAF-1 subunit A CAF-I 150 kDa subunit CAF-I p150 CAF-Ip150 Cac1p chromatin assembly factor 1 subunit A chromatin assembly factor I p150 subunit p150 Chaf1a (Mmus) ADP-ribose-L-arginine cleaving enzyme ADP-ribosylarginine hydrolase Arh1 [Protein ADP-ribosylarginine] hydrolase Adprh (Mmus) 2610033C09Rik transmembrane protein 39A Tmem39a (Mmus) 2810021C21Rik 4930455C21Rik AV135763 TIMM domain containing-protein 1 complex I assembly factor TIMMDC1, mitochondrial translocase of inner mitochondrial membrane domain-containing protein 1 transmembrane protein C3orf1 homolog Timmdc1 (Mmus) AA986889 Ps-pla1 Pspla1 phosphatidylserine-specific phospholipase A1 phospholipase A1 member A Pla1a (Mmus) AA959861 AW476101 BM28 CDCL1 DNA replication licensing factor MCM2 Mcmd2 mKIAA0030 mini chromosome maintenance deficient 2 minichromosome maintenance deficient 2 mitotin minichromosome maintenance protein 2 homolog nuclear protein BM28 Mcm2 (Mmus) 40kDa G protein-coupled receptor 175 Gpr175 Tpra40 integral membrane protein GPR175 transmembrane domain protein of 40 kDa regulated in adipocytes transmembrane domain protein regulated in adipocytes 40 kDa transmembrane protein adipocyte-associated 1 Tpra1 (Mmus) EGR-1-binding protein 1 NGFI-A-binding protein 1 Nab1 (Mmus) AA409984 CD97 antigen Cd97 EGF-TM7 receptor TM7LN1 adhesion G protein-coupled receptor E5 leukocyte antigen CD97 Adgre5 (Mmus) AW538159 Cdw217 IL-17 receptor A IL-17RA Il17r VDw217 interleukin-17 receptor A Il17ra (Mmus) C77966 C80098 C81607 D130003D08Rik Lamb-1 Lamb1-1 laminin B1 chain laminin B1 subunit 1 laminin subunit beta-1 laminin-1 subunit beta laminin-10 subunit beta laminin-111 laminin-12 subunit beta laminin-2 subunit beta laminin-6 subunit beta laminin-8 subunit beta Lamb1 (Mmus) AI854248 KCa2.1 SK1 SKCa 1 SKCa1 small conductance calcium-activated potassium channel protein 1 Kcnn1 (Mmus) 4632416I05Rik Ilad1 arrestin domain-containing protein 2 induced by lysergic acid diethylamide-1 Arrdc2 (Mmus) G substrate Gsbs Ppp1r2 protein phosphatase 1 regulatory subunit 17 protein phosphatase 1, regulatory (inhibitor) 2 Ppp1r17 (Mmus) CD36 antigen FAT GPIIIB GPIV PAS IV PAS-4 Scarb3 fatty acid translocase glycoprotein IIIb platelet glycoprotein 4 platelet glycoprotein IV Cd36 (Mmus) 5930412N11Rik JNK kinase 2 JNK-activating kinase 2 JNKK 2 Jnkk2 MAP kinase kinase 7 MAPK/ERK kinase 7 MAPKK 7 MEK 7 Mapkk7 Mek7 Mkk7 Prkmk7 c-Jun N-terminal kinase kinase 2 dual specificity mitogen-activated protein kinase kinase 7 protein kinase, mitogen activated, kinase 7 sek2 Map2k7 (Mmus) 0710005E20Rik D8Ertd118e Mimt44 Tim44 mitochondrial import inner membrane translocase subunit TIM44 translocator of inner mitochondrial membrane 44 translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed Timm44 (Mmus) 100 kDa coated vesicle protein C 2410074K14Rik AF006990 AP-2 complex subunit alpha-2 AW146353 Adtab C78001 L25 adapter-related protein complex 2 alpha-2 subunit adapter-related protein complex 2 subunit alpha-2 adaptor protein complex AP-2 subunit alpha-2 adaptor protein complex AP-2, alpha 2 subunit adaptor-related protein complex 2 subunit alpha-2 adaptor-related protein complex AP-2, alpha 2 subunit alpha-C adaptin alpha-adaptin C alpha2-adaptin clathrin assembly protein complex 2 alpha-C large chain plasma membrane adaptor HA2/AP2 adaptin alpha C subunit Ap2a2 (Mmus) 1810009G08Rik DNA 5'-kinase/3'-phosphatase PNK bifunctional polynucleotide phosphatase/kinase Pnkp (Mmus) 2610034E13Rik 2610529E18Rik ESTM2 mediator of RNA polymerase II transcription subunit 25 mediator of RNA polymerase II transcription, subunit 9 homolog Med25 (Mmus) 1200005K12Rik Auberger b antigen B-CAM B-CAM cell surface glycoprotein Gplu Lu Lutheran blood group basal cell adhesion molecule lutheran antigen lutheran glycoprotein Bcam (Mmus) HS9 N14 cleft lip and palate transmembrane protein 1 homolog thymic epithelial cell surface antigen Clptm1 (Mmus) shep transcription factor RelB Relb (Mmus) AW539759 Mom35 Tom40 haymaker protein mitochondrial import receptor subunit TOM40 homolog mitochondrial outer membrane protein 35 mitochondrial outer membrane protein of 35 kDa translocase of outer membrane 40 kDa subunit homolog translocase of outer mitochondrial membrane 40 homolog Tomm40 (Mmus) AI255918 Apo-E apolipoprotein E Apoe (Mmus) apo-CII apoC-II apolipoprotein C-II Apoc2 (Mmus) 1700058O05Rik BE629963 C330012F01Rik C86454 HMG box transcription factor 1 HMG box-containing protein 1 Hbp1 (Mmus) AI451071 AW061005 PKARIIbeta Pkarb2 RII(beta) cAMP-dependent protein kinase type II-beta regulatory subunit Prkar2b (Mmus) AA408329 AI843786 Kip1 cyclin-dependent kinase inhibitor 1B cyclin-dependent kinase inhibitor p27 p27 p27Kip1 Cdkn1b (Mmus) EZF Gklf Krueppel-like factor 4 Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF) Zie epithelial zinc finger protein EZF gut-enriched krueppel-like factor Klf4 (Mmus) AA408894 AP-1 complex subunit mu-1 AP-mu chain family member mu1A AP47 Adtm1A Cltnm adapter-related protein complex 1 subunit mu-1 adaptor protein complex AP-1 mu-1 subunit adaptor-related protein complex 1 mu-1 subunit clathrin assembly protein complex 1 medium chain 1 clathrin assembly protein complex 1 mu-1 medium chain 1 clathrin coat assembly protein AP47 clathrin coat-associated protein AP47 golgi adaptor HA1/AP1 adaptin mu-1 subunit mu-adaptin 1 mu1A mu1A-adaptin Ap1m1 (Mmus) AA409338 Mel cell line NK14 derived transforming oncogene oncogene c-mel ras-related protein Rab-8A Rab8a (Mmus) HMG-17 Hmg17 high mobility group nucleosome-binding domain-containing protein 2 high mobility group protein 17 non-histone chromosomal protein HMG-17 Hmgn2 (Mmus) 2510049I19Rik AW822030 OTAG-12 Otag12 ovarian tumor associated gene-12 protein FAM32A Fam32a (Mmus) ESE-1 ESX ETS-related transcription factor Elf-3 epithelial-restricted with serine box epithelium-restricted Ets protein ESX epithelium-specific Ets transcription factor 1 jen Elf3 (Mmus) AHOH AHOHase AI159681 AI196010 Ah-2 Ahh-1 CYPIIC29 Cyp2c P450-2C aldehyde oxygenase cytochrome P-450 MUT-2 cytochrome P450 2C29 cytochrome P450, 2c29 Cyp2c29 (Mmus) 0610035N01Rik 6530409L22Rik AW124774 MENTHO MLN64 N-terminal domain homolog STARD3 N-terminal-like protein Stard3nl (Mmus) AA408040 Lkb1 Par-4 R75140 liver kinase B1 homolog serine/threonine-protein kinase 11 serine/threonine-protein kinase LKB1 serine/threonine-protein kinase STK11 Stk11 (Mmus) CEK7-ligand CEK7L EPH related receptor tyrosine kinase ligand 6 Elf1 Epl6 Eplg6 Lerk6 ephrin A6 ephrin-A2 Efna2 (Mmus) 0610008F14Rik 1500000I11Rik AA960090 AI876556 ATP synthase F1 subunit delta ATP synthase subunit delta, mitochondrial AU020773 Atp5f1d C85518 F-ATPase delta subunit Atp5d (Mmus) ANP receptor AU020526 PP5 protein phosphatase T serine/threonine-protein phosphatase 5 Ppp5c (Mmus) 1810022J16Rik AI646528 CDC2-related kinase 7 CDC2-related kinase, arginine/serine-rich CDC2-related protein kinase 7 Crk7 Crkrs D11Ertd752e Pksc cell division cycle 2-related protein kinase 7 cell division protein kinase 12 cyclin-dependent kinase 12 protein kinase for splicing component Cdk12 (Mmus) 4933403G17Rik HSL REH hormone-sensitive lipase monoacylglycerol lipase LIPE retinyl ester hydrolase Lipe (Mmus) 2610005M20Rik AI747451 AU021353 PAF acetylhydrolase 30 kDa subunit PAF-AH 30 kDa subunit PAF-AH subunit beta Pafahb mus[b] platelet-activating factor acetylhydrolase IB subunit alpha2 platelet-activating factor acetylhydrolase IB subunit beta Pafah1b2 (Mmus) AD3 BUB2-like protein 1 GRAM domain HBLP1 TBC1 domain family member 8 VRP vascular Rab-GAP/TBC-containing protein Tbc1d8 (Mmus) 2410015L18Rik C40 CCR4-NOT transcription complex subunit 11 D1Bwg0212e UPF0760 protein C2orf29 homolog Cnot11 (Mmus) AA408729 AL023014 AL024341 AU040424 C78366 Glut-3 Glut3 glucose transporter type 3, brain solute carrier family 2, facilitated glucose transporter member 3 Slc2a3 (Mmus) Fhx fork head homologous X forkhead box protein J2 Foxj2 (Mmus) 2210417O06Rik 2900070H08Rik Sor sorcin Sri (Mmus) 9930034O06Rik DGS-C Dgsc DiGeorge syndrome gene c DiGeorge syndrome protein C Idd Lan Sez12 integral membrane protein DGCR2/IDD mKIAA0163 seizure-related membrane-bound adhesion protein Dgcr2 (Mmus) C920001K05Rik IRF-3 interferon regulatory factor 3 Irf3 (Mmus) 2810475P17Rik 5430429M05Rik Bcl-L12 Bcl2-L12 bcl-2-like protein 12 Bcl2l12 (Mmus) uncharacterized protein LOC224893 Zfp959 (Mmus) E130307M08Rik MPN domain-containing protein Mpnd (Mmus) C77078 EEN SH3 domain protein 2B SH3 domain-containing GRB2-like protein 1 SH3P8 Sh3d2b endophilin II endophilin-2 endophilin-A2 Sh3gl1 (Mmus) EBI-3 IL-27 IL-27 subunit beta IL-27B epstein-Barr virus-induced gene 3 protein homolog interleukin-27 subunit beta Ebi3 (Mmus) 2900016D05Rik AI413813 Ccdc94 YJU2 splicing factor homolog coiled-coil domain containing 94 coiled-coil domain-containing protein 94 splicing factor YJU2 Ccdc94 (Mmus) A430087B05Rik AI256741 E3 SUMO-protein ligase RanBP2 E3 SUMO-protein transferase RanBP2 NUP358 ran-binding protein 2 Ranbp2 (Mmus) ED1R ED3 ED5 EDA-A1R EDA3 anhidrotic ectodysplasin receptor 1 dl downless ectodermal dysplasia receptor tumor necrosis factor receptor superfamily member EDAR Edar (Mmus) G protein-coupled receptor kinase 5 Gprk5 g protein-coupled receptor kinase GRK5 Grk5 (Mmus) b2b2866Clo dishevelled 3, dsh homolog segment polarity protein dishevelled homolog DVL-3 Dvl3 (Mmus) AI326318 ATP-binding cassette sub-family F member 3 AU016058 BB119416 Abcf3 (Mmus) C81315 eIF-2B GDP-GTP exchange factor subunit epsilon translation initiation factor eIF-2B subunit epsilon Eif2b5 (Mmus) ARF nucleotide-binding site opener ARNO CLM2 PH, SEC7 and coiled-coil domain-containing protein 2 Pscd2 SEC7 homolog B cytohesin-2 mSec7-2 pleckstrin homology, Sec7 and coiled-coil domains 2 Cyth2 (Mmus) AI326997 BB173635 ST2B1 SULT2B alcohol sulfotransferase hydroxysteroid sulfotransferase 2 sulfotransferase 2B sulfotransferase 2B1 Sult2b1 (Mmus) CA-RP II CA-RP XI CA-XI CARP XI CARP-2 Ca11 carbonic anhydrase-related protein 11 carbonic anhydrase-related protein 2 Car11 (Mmus) 4933422O14Rik 9630002F18 AI845682 AI848168 BB075781 D17Bwg0511e DAP-1 beta GKAP/SAPAP GKPA/SAPAP Gkap PSD-95/SAP90-binding protein 1 SAP90/PSD-95 associated protein 1 Sapap1 discs, large homolog-associated protein 1 disks large-associated protein 1 guanylate kinase-associated protein mKIAA4162 Dlgap1 (Mmus) C2H2 zinc finger protein PLAG1 pleiomorphic adenoma gene 1 protein zinc finger protein PLAG1 Plag1 (Mmus) AI849071 B cell/myeloid kinase Bmk hematopoietic cell kinase p56-HCK/p59-HCK tyrosine-protein kinase HCK Hck (Mmus) 1110017G11Rik 39S ribosomal protein L4, mitochondrial L4mt MRP-L4 Mrpl4 (Mmus) INRF2 NRF2 cytosolic inhibitor cytosolic inhibitor of Nrf2 kelch-like ECH-associated protein 1 mKIAA0132 ring canal protein Keap1 (Mmus) AP-1 complex subunit mu-2 AP-mu chain family member mu1B D9Ertd818e [m]1B adaptor protein complex AP-1 subunit mu-2 adaptor-related protein complex 1 mu-2 subunit adaptor-related protein complex 1 subunit mu-2 adaptor-related protein complex AP-1, mu 2 subunit clathrin assembly protein complex 1 medium chain 2 clathrin assembly protein complex 1 mu-2 medium chain 2 golgi adaptor HA1/AP1 adaptin mu-2 subunit mu-adaptin 2 mu1B mu1B-adaptin Ap1m2 (Mmus) AI593353 AW537898 CFR CFR-1 E-selectin ligand 1 ESL-1 Golgi apparatus protein 1 MG-160 MG160 Selel golgi sialoglycoprotein MG-160 selectin, endothelial cell, ligand Glg1 (Mmus) 1700042F02Rik 1700056N23Rik ATPIK SAPLT phospholipid-transporting ATPase IK sperm aminophospholipid transporter spermatozoan aminophospholipid translocase Atp8b3 (Mmus) 2610037C03Rik 4930512K17Rik BTB/POZ domain-containing protein 2 Btbd2 (Mmus) 2810429I12Rik AI463719 CKI-gamma 2 casein kinase I casein kinase I isoform gamma-2 Csnk1g2 (Mmus) 1700013O15Rik BC005632 D10Bwg1364e Fam108a abhydrolase domain-containing protein 17A abhydrolase domain-containing protein FAM108A alpha/beta hydrolase domain-containing protein 17A family with sequence similarity 108, member A mFLJ00358 protein protein ABHD17A Abhd17a (Mmus) 5330417K06Rik A630029F06 AV218468 MOB kinase activator 3A MOB1, Mps One Binder kinase activator-like 2A Mobkl2a mob1 homolog 2A mps one binder kinase activator-like 2A Mob3a (Mmus) Beta3 CAB3 Ca(v)beta3 Cchb3 calcium channel voltage-dependent subunit beta 3 voltage-dependent L-type calcium channel subunit beta-3 Cacnb3 (Mmus) 4933417K04Rik AI428139 AU020178 NYD-SP28 coiled-coil domain-containing protein 65 dynein regulatory complex subunit 2 testis development protein NYD-SP28 Ccdc65 (Mmus) 1110002O23Rik 19 kDa FK506-binding protein 19 kDa FKBP FKBP-11 FKBP-19 PPIase FKBP11 peptidyl-prolyl cis-trans isomerase FKBP11 rotamase Fkbp11 (Mmus) 3110082M05Rik 4921506D17Rik DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 probable ATP-dependent RNA helicase DDX23 Ddx23 (Mmus) 5'-3' exonuclease PLD3 PLD 3 Sam-9 choline phosphatase 3 phosphatidylcholine-hydrolyzing phospholipase D3 phospholipase D3 schwannoma-associated protein 9 Pld3 (Mmus) GluK5 GluRgamma2 KA2 gluR gamma-2 glutamate receptor KA-2 glutamate receptor gamma-2 glutamate receptor ionotropic, kainate 5 Grik5 (Mmus) B-cell antigen receptor complex-associated protein alpha chain Ig-alpha Iga Igalpha Ly-54 Ly54 MB-1 membrane glycoprotein mb-1 membrane-bound immunoglobulin-associated protein surface IgM-associated protein Cd79a (Mmus) 2310040I06Rik GTP binding protein associated protein 1 Gbpap1 PRA1 PRA1 family protein 1 prenylated Rab acceptor protein 1 prenylin Rabac1 (Mmus) AI414410 ETS domain transcriptional repressor PE1 ETS translocation variant 3 ETS-domain protein METS Pe1 ets variant gene 3 mitogenic Ets transcriptional suppressor METS Etv3 (Mmus) 80K-H PKCSH alpha glucosidase II, beta-subunit carbohydrate processing enzyme of the endoplasmic reticulum glucosidase 2 subunit beta glucosidase II beta-subunit hepatocystin protein kinase C substrate 60.1 kDa protein heavy chain Prkcsh (Mmus) 2600009P04Rik ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) ELAV-like protein 3 HU-antigen C Huc PLE21 mHuC Elavl3 (Mmus) 2610528C18Rik ras-related protein Rab-3B Rab3b (Mmus) 1700007J08Rik AI314453 AI875066 SIAT8-F ST8Sia VI ST8SiaVI Siat8f alpha-2, 8-sialyltransferase alpha-2,8-sialyltransferase 8F alpha2,8-sialyltransferase VI sialyltransferase 8 (alpha-2, 8-sialyltransferase) F sialyltransferase 8F sialyltransferase St8Sia VI sialytransferase St8Sia VI St8sia6 (Mmus) Fc receptor, IgG, alpha chain transporter FcRn IgG receptor FcRn large subunit p51 igG Fc fragment receptor transporter alpha chain neonatal Fc receptor Fcgrt (Mmus) 2310061K06Rik CGI-25 E3 ubiquitin-protein ligase NOSIP RING-type E3 ubiquitin transferase NOSIP nitric oxide synthase-interacting protein Nosip (Mmus) 1110061L23Rik 4933413A04Rik Nop17 PIH1 domain-containing protein 1 nucleolar protein 17 homolog Pih1d1 (Mmus) 40S ribosomal protein S11 Rps11 (Mmus) AL033283 AL033321 AU019549 DRB sensitivity-inducing factor large subunit DSIF large subunit Spt5 Supt5h suppressor of Ty 5 homolog transcription elongation factor SPT5 Supt5 (Mmus) M-Delta-3 delta-like 3 delta-like protein 3 delta3 drosophila Delta homolog 3 pu pudgy Dll3 (Mmus) 5730511K23Rik AA675045 Paf1, RNA polymerase II associated factor, homolog RNA polymerase II-associated factor 1 homolog Paf1 (Mmus) 2810403L02Rik AU015082 TIM50L mitochondrial import inner membrane translocase subunit TIM50 translocase of inner mitochondrial membrane 50 homolog Timm50 (Mmus) 2810405O22Rik AU020902 Ixl intersex-like protein mediator of RNA polymerase II transcription subunit 29 Med29 (Mmus) B830009D06Rik bic-D 1 bicaudal D homolog 1 protein bicaudal D homolog 1 Bicd1 (Mmus) 9430068N19Rik AA727311 Aph2 D1Dau13e Kiaa0253 Nct mKIAA0253 nicastrin Ncstn (Mmus) Pxf peroxin-19 peroxisomal biogenesis factor 19 peroxisomal farnesylated protein peroxisome biogenesis factor 19 Pex19 (Mmus) AW049870 C630010D02Rik Lnap1ip PAHX-AP#1 PAHX-AP1 PAHXAP1 lupus nephritis-associated peptide 1 interacting protein phytanoyl-CoA hydroxylase-associated protein 1 phytanoyl-CoA hydroxylase-interacting protein Phyhip (Mmus) CRF 2 receptor CRF-R-2 CRF-R2 CRF-RB CRFR-2 CRFR2alpha CRFR2beta CRH-R-2 CRH-R2 Crfr2 corticotropin releasing factor receptor type 2 beta corticotropin-releasing factor 2 corticotropin-releasing factor receptor 2 Crhr2 (Mmus) Temt amine N-methyltransferase aromatic alkylamine N-methyltransferase arylamine N-methyltransferase indolamine N-methyltransferase indolethylamine N-methyltransferase nicotine N-methyltransferase thioether S-methyltransferase Inmt (Mmus) 1810054N16Rik CYPIVF3 Cyp4f3 Cypf18 cytochrome P450 4F3 cytochrome P450 CYP4F18 cytochrome P450, 4f18 cytochrome P450-LTB-omega leukotriene-B(4) 20-monooxygenase 2 leukotriene-B(4) omega-1/omega-2 hydroxylase leukotriene-B(4) omega-hydroxylase 2 Cyp4f18 (Mmus) B930086D20Rik IMP dehydrogenase 1 IMPD 1 IMPDH 1 IMPDH-I inosine 5'-phosphate dehydrogenase 1 inosine-5'-monophosphate dehydrogenase 1 Impdh1 (Mmus) Cea-3 Cea3 carcinoembryonic antigen 3 mmCGM6 pregnancy specific glycoprotein 18 pregnancy specific glycoprotein 18; carcinoembryonic antigen 3 Psg18 (Mmus) 2210015O03Rik 5031436O03Rik T-DSP11 VHR dual specificity protein phosphatase 3 vaccinia H1-related phosphatase Dusp3 (Mmus) Pro-1 Pro1 Ym24d07 proline dehydrogenase 1, mitochondrial proline dehydrogenase, mitochondrial proline oxidase Prodh (Mmus) AI462402 D16H22S1269E Dgcr1 Dgcr14 Dgsi DiGeorge syndrome critical region gene 14 DiGeorge syndrome critical region protein 14 ES2 Es2el diGeorge syndrome critical region 14 homolog protein DGCR14 splicing factor ESS-2 homolog Dgcr14 (Mmus) 1300019P08Rik 2610100G11Rik AI194714 Ctp Dgsj DiGeorge syndrome gene j Slc20a3 citrate transport protein solute carrier family 25 member 1 tricarboxylate carrier protein tricarboxylate transport protein, mitochondrial Slc25a1 (Mmus) DiGeorge syndrome chromosome region 6 diGeorge syndrome critical region 6 homolog protein DGCR6 Dgcr6 (Mmus) 6030432F18 AI323681 CD167 antigen-like family member A CD167a Cak Nep PTK3A cell adhesion kinase discoidin receptor tyrosine kinase epithelial discoidin domain receptor 1 epithelial discoidin domain-containing receptor 1 protein-tyrosine kinase MPK-6 tyrosine kinase DDR tyrosine-protein kinase CAK Ddr1 (Mmus) AI663993 IEX-1 cAMP inducible gene 3 cI-3 gly96 immediate early protein GLY96 immediate early response 3 protein radiation-inducible immediate-early gene IEX-1 Ier3 (Mmus) osteosarcoma oncoprotein B FosB protein FosB protein fosB transcription factor AP-1 subunit FosB Fosb (Mmus) 1200014P03Rik AA408085 AW146303 KLC 4 Knsl8 kinesin light chain 4 kinesin-like 8 kinesin-like protein 8 Klc4 (Mmus) DNA excision repair protein ERCC-1 Ercc-1 Ercc1 (Mmus) 17-alpha-hydroxyprogesterone aldolase CYPXVII Cyp17 cytochrome P450 17A1 cytochrome P450, 17 cytochrome P450, 17a1 cytochrome P450-C17 cytochrome P450c17 p450c17 steroid 17-alpha hydroxylase steroid 17-alpha-hydroxylase/17,20 lyase steroid 17-alpha-monooxygenase Cyp17a1 (Mmus) 2310045H08Rik Cyt19 S-adenosyl-L-methionine:arsenic(III) methyltransferase S-adenosylmethionine:arsenic (III) methyltransferase arsenic (+3 oxidation state) methyltransferase arsenite methyltransferase methylarsonite methyltransferase methyltransferase Cyt19 As3mt (Mmus) AW146114 homer homolog 3 homer protein homolog 3 homer, neuronal immediate early gene, 3 homer-3 Homer3 (Mmus) AI413414 CREB-regulated transcription coactivator 1 Mect1 R74955 TORC-1 TORC1 mKIAA0616 mucoepidermoid carcinoma translocated 1 mucoepidermoid carcinoma translocated protein 1 homolog transducer of CREB protein 1 transducer of regulated cAMP response element-binding protein 1 Crtc1 (Mmus) 0610009J22Rik AW557025 C77903 RING finger protein 215 Rnf215 (Mmus) 1300013M05Rik SEC14-like 2 SEC14-like protein 2 Spf TAP alpha-tocopherol-associated protein Sec14l2 (Mmus) 1700013A01Rik 1700056A21Rik cell death regulator Aven mAven-L mAven-S Aven (Mmus) D3Ertd555e ceruloplasmin ferroxidase Cp (Mmus) 1200003H03Rik COT peroxisomal carnitine O-octanoyltransferase Crot (Mmus) 90 kDa ribosomal protein S6 kinase 1 MAP kinase-activated protein kinase 1a MAPK-activated protein kinase 1a MAPKAP kinase 1a Mapkapk-1a Rsk Rsk-1 Rsk1 S6K-alpha-1 p90-Rsk1 p90Rsk1 p90S6K p90rsk ribosomal protein S6 kinase alpha-1 ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1 Rps6ka1 (Mmus) CR calretinin Calb2 (Mmus) A330064G03Rik Ascc3l1 BC011390 BRR2 homolog HELIC2 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family) U5-200-KD U5-200KD activating signal cointegrator 1 complex subunit 3-like 1 Snrnp200 (Mmus) AW210570 WD repeat domain 39 WD repeat-containing protein 39 WD40 protein Ciao1 Wdr39 cytosolic iron-sulfur protein assembly 1 homolog probable cytosolic iron-sulfur protein assembly protein CIAO1 Ciao1 (Mmus) HA synthase 1 HAS hyaluronan synthase 1 hyaluronan synthase1 hyaluronate synthase 1 hyaluronic acid synthase 1 Has1 (Mmus) 2810417N14Rik BB223262 C530024J06Rik PAF65-alpha PCAF-associated factor 65-alpha Paf65a TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor Taf6l (Mmus) 2900053I11Rik C730043J18Rik INSIG-2 membrane protein Insig-2 insulin-induced gene 2 protein Insig2 (Mmus) IPOA7 Kpna5 NPI-2 importin alpha 7 importin alpha-S2 importin subunit alpha-7 karyopherin (importin) alpha 5 karyopherin subunit alpha-6 Kpna6 (Mmus) Man1a1 PCR1 alpha-1,2-mannosidase IA man(9)-alpha-mannosidase man9-mannosidase mannosidase alpha class 1A member 1 mannosyl-oligosaccharide 1,2-alpha-mannosidase IA mannosyl-oligosaccharide alpha-1,2-mannosidase processing alpha-1,2-mannosidase IA Man1a (Mmus) 9130023N17Rik IP3 3-kinase C IP3K C inositol-trisphosphate 3-kinase C insP 3-kinase C Itpkc (Mmus) 0610012P18Rik Adck4 aarF domain containing kinase 4 aarF domain-containing protein kinase 4 atypical kinase COQ8B, mitochondrial coenzyme Q protein 8B Coq8b (Mmus) 2610007E11Rik 4432404P07Rik SMAP bromodomain-containing protein 8 Brd8 (Mmus) AA415432 Rab6kifl Rabkinesin-6 kinesin-like protein 174 kinesin-like protein KIF20A rab6-interacting kinesin-like protein Kif20a (Mmus) 0610012A19Rik Farsla pheRS phenylalanine--tRNA ligase alpha chain phenylalanine--tRNA ligase alpha subunit phenylalanine-tRNA synthetase-like, alpha subunit phenylalanyl-tRNA synthetase alpha chain Farsa (Mmus) 9030411L18 AI266902 D17825 GCD glutaryl-CoA dehydrogenase, mitochondrial Gcdh (Mmus) MAST205 Mtssk microtubule associated testis specific serine/threonine protein kinase microtubule-associated serine/threonine-protein kinase 2 Mast2 (Mmus) Dnase2a (Mmus) 2310040P19Rik AL024030 HR23A RAD23a homolog UV excision repair protein RAD23 homolog A mHR23A Rad23a (Mmus) CRP55 CRT Calregulin ERp60 HACBP calreticulin endoplasmic reticulum resident protein 60 Calr (Mmus) 1700013H19Rik AA407907 Cesc1 central element synaptonemal complex 1 central element synaptonemal complex protein 1 synaptonemal complex central element protein 2 Syce2 (Mmus) AI225870 B130038B15Rik CAG-8 CAG80 NFATL1 OREBP T-cell transcription factor NFAT5 TonEBP mKIAA0827 nfatz nuclear factor of activated T-cells 5 rel domain-containing transcription factor NFAT5 tonicity-responsive enhancer binding protein Nfat5 (Mmus) 1700021I09Rik ART-4 Nob1p PSMD8 binding protein 1 Psmd8bp1 RNA-binding protein NOB1 nin one binding protein Nob1 (Mmus) AV001255 DT-diaphorase Dia4 Dtd NAD(P)H dehydrogenase (quinone) NAD(P)H dehydrogenase [quinone] 1 NAD(P)H menadione oxidoreductase 1, dioxin inducible NAD(P)H:quinone oxidoreductase 1 Nmo-1 Nmo1 Nmor1 Ox-1 Ox1 Qr1 azoreductase diaphorase 4 (NADH/NADPH) menadione reductase phylloquinone reductase quinone reductase 1 Nqo1 (Mmus) 2410127E16Rik Liprin-alpha3 PTPRF-interacting protein alpha-3 liprin-alpha-3 protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3 Ppfia3 (Mmus) Gys3 MGS glycogen [starch] synthase, muscle glycogen synthase 3, brain Gys1 (Mmus) mp47 p47 reptin ruvB-like 2 Ruvbl2 (Mmus) LIN-7B MALS-2 Veli2 lin 7 homolog b lin-7 homolog B mammalian lin-seven protein 2 protein lin-7 homolog B veli-2 vertebrate homolog of C. elegans Lin-7 type 2 vertebrate lin-7 homolog 2 Lin7b (Mmus) apoptosis regulator BAX Bax (Mmus) CD127 IL-7 receptor alpha chain IL-7 receptor subunit alpha IL-7R subunit alpha IL-7R-alpha IL-7RA IL-7Ralpha interleukin 7 receptor alpha chain interleukin-7 receptor subunit alpha Il7r (Mmus) AI661103 Hmgts TS-HMG mtTFA testis-specific HMG-box protein m-tsHMG testis-specific high mobility group protein transcription factor A, mitochondrial tsHMG Tfam (Mmus) AA409460 AA409461 C330034P10Rik D330034E10Rik Hszfp36 KRAB13 ZFP-36 zinc finger protein Zfp78 zinc finger protein 81 Zfp81 (Mmus) EFL-6 ELF-3 Elk-L3 Epl8 LERK-8 NLERK-2 ephrin-B3 Efnb3 (Mmus) 1200017E07Rik 1810073C06Rik AA690185 monocyte to macrophage differentiation factor monocyte to macrophage differentiation protein progestin and adipoQ receptor family member 11 progestin and adipoQ receptor family member XI Mmd (Mmus) E230015K02Rik hepatic leukemia factor Hlf (Mmus) 2310056P07Rik E2-induced gene 5 protein homolog HGTD-P growth and transformation-dependent protein protein FAM162A Fam162a (Mmus) 60S ribosomal protein L8 Rpl8 (Mmus) 0710001G23Rik G protein-coupled receptor, family C, group 1, member C Gprc1c mGlu3 mGluR3 metabotropic glutamate receptor 3 Grm3 (Mmus) 1500004K09Rik 2310079I02Rik 9330163K02Rik A830008M03Rik AU067692 AW558684 Hspc116 SSDP2 sequence-specific single-stranded-DNA-binding protein 2 single-stranded DNA-binding protein 2 Ssbp2 (Mmus) 2010322C19Rik AW554273 B230118H11Rik E3 ubiquitin-protein ligase FANCL PHD finger protein 9 Phf9 Pog RING-type E3 ubiquitin transferase FANCL fanconi anemia group L protein homolog gcd germ cell deficient proliferation of germ cells protein Fancl (Mmus) 6430517E21Rik BB361039 BMP/retinoic acid-inducible neural-specific protein 2 Fam5b family with sequence similarity 5, member B mKIAA1747 protein FAM5B Brinp2 (Mmus) GST class-mu 5 fibrous sheath component 2 fsc2 glutathione S-transferase Mu 5 Gstm5 (Mmus) 0610005A07Rik AI894236 Cd203c GST class-mu 7 glutathione S-transferase Mu 7 Gstm7 (Mmus) Fsc2 GST class-mu 3 glutathione S-transferase GT9.3 glutathione S-transferase Mu 3 mGSTM5 Gstm3 (Mmus) 1110034C02Rik AW109958 Aprf acute phase response factor signal transducer and activator of transcription 3 Stat3 (Mmus) AA959963 STAT5 mammary gland factor STAT5A signal transducer and activator of transcription 5A Stat5a (Mmus) 2310075E07Rik AW546441 Cav-p60 Cavin Ptrf caveolae-associated protein 1 cavin-1 polymerase I and transcript release factor Cavin1 (Mmus) 2610017K16Rik Mlk3 PTK1 SPRK mitogen-activated protein kinase kinase kinase 11 mixed lineage kinase 3 Map3k11 (Mmus) 2410016A19Rik AW554154 PKB PKB beta PKBbeta RAC-PK-beta RAC-beta serine/threonine-protein kinase protein kinase Akt-2 protein kinase B, beta Akt2 (Mmus) 1200003J13Rik 1810053A11Rik C81173 DnaJ (Hsp40) homolog, subfamily A, member 3 Tid-1 Tid1l dnaJ homolog subfamily A member 3, mitochondrial dnaJ protein Tid-1 mTid-1 tumorous imaginal discs protein Tid56 homolog Dnaja3 (Mmus) HO-2 HO2 heme oxygenase (decycling) 2 heme oxygenase 2 Hmox2 (Mmus) 2700048O17Rik 5730403B10Rik AU018521 AW742692 CDIP LITAF-like protein cell death-inducing p53-target protein 1 Cdip1 (Mmus) AV006891 B230120H23Rik HCCS-4 MLK-like mitogen-activated protein triple kinase MLK-related kinase MLTK MLTKalpha MLTKbeta MRK Zak human cervical cancer suppressor gene 4 protein leucine zipper- and sterile alpha motif kinase ZAK leucine zipper- and sterile alpha motif-containing kinase mitogen-activated protein kinase kinase kinase 20 mitogen-activated protein kinase kinase kinase MLT mixed lineage kinase-related kinase sterile alpha motif and leucine zipper containing kinase AZK Map3k20 (Mmus) 0610040D20Rik 2900052N06Rik CWC15 homolog Ed1 c11orf5 embryonic development factor 1 mED1 nucleoporin protein CWC15 homolog spliceosome-associated protein CWC15 homolog Cwc15 (Mmus) Pro-alpha3(V) collagen alpha-3(V) chain procollagen, type V, alpha 3 Col5a3 (Mmus) Cxxc9 DNA (cytosine-5)-methyltransferase 1 DNA MTase MmuI DNA methyltransferase MmuI Dnmt Dnmt1o MCMT MTase Met-1 Met1 MommeD2 m.MmuI Dnmt1 (Mmus) A230087P06Rik SSF1 second-step splicing factor 1 ssf-1 suppressor of SWI4 1 homolog suppressor of sterile four 1 Ppan (Mmus) AI593246 AW260363 Arp2 angiopoietin-like protein 2 angiopoietin-related protein 2 Angptl2 (Mmus) A430040I15 BII Cach6 Cacnl1a6 Cav2.3 Cchra1 alpha1E brain calcium channel II calcium channel, L type, alpha-1 polypeptide calcium channel, voltage-dependent, L type, alpha 1E subunit voltage-dependent R-type calcium channel subunit alpha-1E voltage-gated calcium channel subunit alpha Cav2.3 Cacna1e (Mmus) AW050276 AW060892 AW822256 BIII Cav2.2 Cchn1a alpha(1B) brain calcium channel III calcium channel, L type, alpha-1 polypeptide calcium channel, voltage-dependent, L type, alpha 1B subunit calcium channel, voltage-dependent, N type, alpha 1B subunit, BIII voltage-dependent N-type calcium channel subunit alpha-1B voltage-gated calcium channel subunit alpha Cav2.2 Cacna1b (Mmus) 3110023L08Rik AA794508 RNA (guanine-9-) methyltransferase domain containing 2 Rg9mtd2 Rnmtd2 tRNA (guanine(9)-N(1))-methyltransferase TRMT10A tRNA methyltransferase 10 homolog A Trmt10a (Mmus) ER81 ETS translocation variant 1 Etsrp81 ets variant gene 1 ets-related protein 81 Etv1 (Mmus) kinesin-like protein KIFC2 Kifc2 (Mmus) AI037048 SGP-1 prosaposin snoRNA MBII-198 sulfated glycoprotein 1 Psap (Mmus) 1110037D23Rik AI848108 AI851264 AW124339 I-kappa-B kinase subunit gamma IKK-gamma IKKAP1 IKKG IKK[g] NEMO NF-kappa-B essential modifier NF-kappa-B essential modulator ikB kinase subunit gamma ikB kinase-associated protein 1 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma inhibitor of nuclear factor kappa-B kinase subunit gamma mFIP-3 Ikbkg (Mmus) Opdc Pax-2 optic disc coloboma paired box gene 2 paired box protein Pax-2 Pax2 (Mmus) (Mt)TrpRS 5730427B17Rik 9430020O07Rik AI413375 TrpRS tryptophan--tRNA ligase, mitochondrial tryptophanyl-tRNA synthetase, mitochondrial Wars2 (Mmus) Atr1 Drpla atrophin-1 dentatorubral pallidoluysian atrophy dentatorubral-pallidoluysian atrophy protein homolog Atn1 (Mmus) AU044498 B-cell receptor-associated protein 37 B-cell receptor-associated protein BAP37 BAP Bap37 Bcap37 REA prohibitin-2 repressor of estrogen receptor activity Phb2 (Mmus) 70Z-SHP Hcph PTPTY-42 Ptp1C SH-PTP1 SH2 phosphatase 1 SHP-1 hcp hematopoietic cell protein-tyrosine phosphatase me motheaten protein-tyrosine phosphatase 1C tyrosine-protein phosphatase non-receptor type 6 Ptpn6 (Mmus) 2-phospho-D-glycerate hydro-lyase AI837106 D6Ertd375e Eno-2 NSE gamma-enolase neural enolase neuron-specific enolase Eno2 (Mmus) 18S rRNA (pseudouridine(1248)-N1)-methyltransferase 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1 18S rRNA Psi1248 methyltransferase C2f EMG1 nucleolar protein homolog Grcc2f gene rich cluster, C2f nucleolar protein EMG1 homolog probable ribosome biogenesis protein NEP1 protein C2f ribosomal RNA small subunit methyltransferase NEP1 ribosome biogenesis protein NEP1 Emg1 (Mmus) 1-acylglycerophosphoserine O-acyltransferase C3f Grcc3f LPC acyltransferase 3 Lpcat Lpeat Lplat5 Lpsat Mboat5 Moact5 O-acyltransferase domain-containing protein 5 Oact5 PTG lyso-PC acyltransferase 3 lyso-PE acyltransferase lyso-PS acyltransferase lysophosphatidylethanolamine acyltransferase lysophosphatidylserine acyltransferase lysophospholipid acyltransferase 5 Lpcat3 (Mmus) 1110004G16Rik ATPase, H+ transporting, V1 subunit F ATPase, vacuolar, 14 kD V-ATPase 14 kDa subunit V-ATPase subunit F V-type proton ATPase subunit F vacuolar proton pump subunit F Atp6v1f (Mmus) CLMF p40 IL-12 p40 subunit IL-12 subunit p40 IL-23 subunit p40 Il-12b Il-12p40 Il12p40 cytotoxic lymphocyte maturation factor 40 kDa subunit interleukin-12 p40 subunit interleukin-12 subunit beta p40 Il12b (Mmus) 5430408K11Rik ClC-5 Clc4-1 Clc5 Clcn4-1 D930009B12Rik DXImx42e H(+)/Cl(-) exchange transporter 5 Sfc13 T25545 chloride channel 4-1 chloride channel 5 chloride channel protein 5 chloride transporter ClC-5 Clcn5 (Mmus) Clc3 H(+)/Cl(-) exchange transporter 3 chloride channel 3 chloride channel protein 3 chloride transporter ClC-3 clC-3 Clcn3 (Mmus) HIF-3-alpha HIF3-alpha HIF3-alpha-1 Ipas MOP7 NEPAS bHLHe17 basic-helix-loop-helix-PAS protein MOP7 hypoxia inducible factor three alpha hypoxia-inducible factor 3-alpha inhibitory PAS domain protein member of PAS protein 7 neonatal and embryonic PAS protein Hif3a (Mmus) 1700020G18Rik GPx-6 GSHPx-6 Ry2d1 glutathione peroxidase 6 odorant-metabolizing protein RY2D1 olfactory Gpx6 (Mmus) AV379049 Arep EGLP GPx-5 GSHPx-5 arMEP24 epididymal secretory glutathione peroxidase epididymis-specific glutathione peroxidase-like protein lysosomal trafficking regulator, long splice form major androgen-regulated protein Gpx5 (Mmus) 3',5'-cyclic-AMP phosphodiesterase 3',5'-cyclic-GMP phosphodiesterase calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C cam-PDE 1C Pde1c (Mmus) 3830408P06Rik AA617408 Drim UTP20, small subunit (SSU) processome component, homolog down-regulated in metastasis protein mDRIM mDRIN small subunit processome component 20 homolog Utp20 (Mmus) AU019198 C76795 Prf Spi-C pu.1-related factor transcription factor Spi-C Spic (Mmus) uncharacterized protein KIAA0408 homolog 9330159F19Rik (Mmus) KIAA0617 cullin-3 Cul3 (Mmus) SOM SRIF SS Smst preprosomatostatin somatostatin Sst (Mmus) IL-11 interleukin-11 Il11 (Mmus) BPFD#36 Gyltl1a LARGE xylosyl- and glucuronyltransferase 1 Large Mbp-1 Mbp1 acetylglucosaminyltransferase-like 1A enr fg froggy glycosyltransferase-like protein LARGE1 like-glycosyltransferase myd myodystrophy xylosyl- and glucuronyltransferase LARGE1 Large1 (Mmus) 2600001H07Rik ATP-dependent 61 kDa nucleolar RNA helicase D11Ertd619e DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 DEAD box protein 56 DEAD-box RNA helicase Noh61 nucleolar RNA helicase homolog probable ATP-dependent RNA helicase DDX56 Ddx56 (Mmus) 1110014L17Rik AI326346 ERS25 endoplasmic reticulum stress-response protein 25 p24 family protein alpha-3 p24alpha3 p26 transmembrane emp24 domain-containing protein 4 transmembrane emp24 protein transport domain containing 4 Tmed4 (Mmus) 9430032K24Rik BC002218 Col26a Collagen XXVI EMI domain containing 2 EMI domain-containing protein 2 Emid2 Emu2 alpha-1 type XXVI collagen collagen alpha-1(XXVI) chain emilin and multimerin domain-containing protein 2 procollagen, type XXVI, alpha 1 Col26a1 (Mmus) 2700049M22Rik AI875481 AU022477 BH3-interacting domain death agonist p22 BID Bid (Mmus) 5730472O18Rik ras-related protein Ral-B v-ral simian leukemia viral oncogene homolog B (ras related) Ralb (Mmus) PP-1G PP1 PP1C gamma 1 PP1C gamma 2 dis2m1 protein phosphatase 1C catalytic subunit serine/threonine-protein phosphatase PP1-gamma catalytic subunit Ppp1cc (Mmus) 1810031F23Rik ABBP-2 AL024055 APOBEC1-binding protein 2 Dj9 DnaJ (Hsp40) homolog, subfamily B, member 11 ER-associated Hsp40 co-chaperone ER-associated dnaJ protein 3 ER-resident protein ERdj3 ERdj3 ERj3p dnaJ homolog subfamily B member 11 endoplasmic reticulum DNA J domain-containing protein 3 Dnajb11 (Mmus) 5730478M09Rik AU015083 BB165076 TBCC domain-containing protein 1 Tbccd1 (Mmus) AW457320 C-type lectin domain family 11 member A Clecsf3 Scgf lymphocyte secreted C-type lectin osteolectin stem cell growth factor Clec11a (Mmus) A930002M05 D430030K24Rik ZF5128 zinc finger protein 324A Zfp324 (Mmus) AI463667 D130058I17Rik GRB2-associated binder 2 GRB2-associated-binding protein 2 Grb2 associated binder 2 PH domain-containing adaptor molecule p97 p97 Gab2 (Mmus) AL022675 AW455561 AW548837 CRN2 coronin 1c coronin-1C coronin-3 Coro1c (Mmus) 1200003J11Rik 1700069J21Rik AA930106 D6Ertd404e D6Ertd772e T6bp TRAF6-binding protein homolog TXBP151 tax1-binding protein 1 homolog Tax1bp1 (Mmus) Cea-2 Cea2 carcinoembryonic antigen 2 mmCGM5 pregnancy specific glycoprotein 17 Psg17 (Mmus) CGM7 Cea-4 Cea4 carcinoembryonic antigen 4 pregnancy specific glycoprotein 19 Psg19 (Mmus) A430072O03Rik C920004C08Rik CE CatE cathepsin E Ctse (Mmus) AI182517 AU040374 N-myc downstream regulated 2 N-myc downstream-regulated gene 2 protein Ndr2 SYLD protein NDRG2 protein Ndr2 Ndrg2 (Mmus) 2310032K15Rik D14Ertd209e Mett11d1 methyltransferase 11 domain containing 1 methyltransferase 11 domain-containing protein 1 methyltransferase-like protein 17, mitochondrial protein RSM22 homolog, mitochondrial Mettl17 (Mmus) E130112L23Rik Gm669 Solo protein SOLO rho guanine nucleotide exchange factor 40 Arhgef40 (Mmus) AI661849 MSws Nte Swiss-cheese neuropathy target esterase patatin-like phospholipase domain-containing protein 6 Pnpla6 (Mmus) 2210015I05Rik TRPML1 mucolipidin mucolipin-1 transient receptor potential-mucolipin 1 Mcoln1 (Mmus) A430078G23Rik AI467246 D030053O22Rik rho guanine nucleotide exchange factor 18 Arhgef18 (Mmus) 6030436C20Rik AI507382 PKN gamma PRK2 Prkcl2 Stk7 protein kinase C-like 2 protein-kinase C-related kinase 2 serine/threonine kinase 7 serine/threonine-protein kinase N2 Pkn2 (Mmus) Siglec-3 gp67 myeloid cell surface antigen CD33 sialic acid-binding Ig-like lectin 3 Cd33 (Mmus) 0610009I16Rik 2810441H06Rik beta-ETF electron transfer flavoprotein subunit beta Etfb (Mmus) 2500004F03Rik natural killer cell protein 7 protein NKG7 Nkg7 (Mmus) C79054 Munc-18-2 Munc-18b Munc18b Sxtbp2 Sxtp2 Unc18-2 Unc18b muSec1 protein unc-18 homolog 2 protein unc-18 homolog B syntaxin binding protein Munc18-2 syntaxin-binding protein 2 Stxbp2 (Mmus) L7 Pcp-2 Purkinje cell protein 2 Purkinje cell-specific protein L7 protein PCD-5 retinal Purkinje cell protein 2 Pcp2 (Mmus) e-SG epsilon-SG epsilon-sarcoglycan Sgce (Mmus) <