format-version: 1.2 ontology: uberon/subsets/excretory-minimal owl-axioms: Prefix(owl:=)\nPrefix(rdf:=)\nPrefix(xml:=)\nPrefix(xsd:=)\nPrefix(rdfs:=)\n\n\nOntology(\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(ObjectProperty())\n\n############################\n# Classes\n############################\n\n# Class: ()\n\nEquivalentClasses( ObjectSomeValuesFrom( ))\n\n# Class: owl:Nothing (owl:Nothing)\n\nSubClassOf(owl:Nothing owl:Nothing)\n\n\n) [Term] id: BFO:0000002 name: continuant relationship: part_of BFO:0000002 ! continuant [Term] id: BFO:0000004 name: independent continuant is_a: BFO:0000002 ! continuant relationship: part_of BFO:0000004 ! independent continuant [Term] id: BFO:0000040 name: material entity is_a: BFO:0000004 ! independent continuant [Term] id: CL:0000474 name: pericardial nephrocyte namespace: cell def: "An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel." [] synonym: "pericardial cell" NARROW [] xref: FBbt:00005058 is_a: CL:0002520 ! nephrocyte [Term] id: CL:0000486 name: garland cell namespace: cell def: "A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae." [] synonym: "garland nephrocyte" BROAD [] xref: BTO:0004596 xref: FBbt:00005059 is_a: CL:0002520 ! nephrocyte [Term] id: CL:0000648 name: kidney granular cell namespace: cell alt_id: CL:0000461 def: "A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation." [] synonym: "JG cell" EXACT [] synonym: "juxtaglomerular cell" BROAD [] synonym: "renin secreting cell" EXACT [] xref: FMA:84138 is_a: CL:1000618 ! juxtaglomerular complex cell [Term] id: CL:0000653 name: glomerular visceral epithelial cell namespace: cell def: "A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells." [] comment: GO has podocyte as a related synonym due to concern this may refer to more than one cell type. However, this did not turn up in my search. If podocyte does refer to more than one cell type, then we should classify the synonym to 'related'[tfm]. synonym: "epithelial cell of visceral layer of glomerular capsule" BROAD [] synonym: "glomerular podocyte" EXACT [] synonym: "podocyte" EXACT [] xref: BTO:0002295 xref: FMA:70967 is_a: CL:0002522 ! renal filtration cell is_a: CL:1000450 ! epithelial cell of glomerular capsule relationship: part_of UBERON:0005751 ! visceral layer of glomerular capsule [Term] id: CL:0000731 name: urothelial cell namespace: cell def: "A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria." [] synonym: "bladder transitional cell" NARROW [] synonym: "transitional epithelial cell of urinary bladder" NARROW [] synonym: "urinary tract transitional epithelial cell" NARROW [] xref: FMA:84127 relationship: part_of UBERON:0000365 ! urothelium [Term] id: CL:0002173 name: extraglomerular mesangial cell namespace: cell def: "A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells." [] synonym: "Goormaghtigh cell" EXACT [] synonym: "lacis cell" RELATED [] synonym: "polar cushion cells" EXACT [] xref: FMA:84143 xref: KUPO:0001033 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:1000618 ! juxtaglomerular complex cell is_a: CL:1000746 ! glomerular cell is_a: CL:1001318 ! renal interstitial pericyte relationship: part_of UBERON:0002321 ! extraglomerular mesangium created_by: tmeehan creation_date: 2010-08-25T02:20:55Z [Term] id: CL:0002188 name: glomerular endothelial cell namespace: cell def: "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate." [] xref: BTO:0004632 xref: FMA:70970 is_a: CL:1000746 ! glomerular cell created_by: tmeehan creation_date: 2010-08-26T10:59:44Z [Term] id: CL:0002201 name: renal beta-intercalated cell namespace: cell def: "A renal intercalated cell that secretes base and reabsorbs acid in the coritcal collecting duct to mantain acid/base balance." [] is_a: CL:0005010 ! renal intercalated cell created_by: tmeehan creation_date: 2010-09-02T01:43:55Z [Term] id: CL:0002305 name: epithelial cell of distal tubule namespace: cell def: "An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH." [] synonym: "kidney distal tubule epithelial cell" EXACT [] xref: FMA:62125 xref: FMA:70981 xref: KUPO:0001055 is_a: CL:1000494 ! nephron tubule epithelial cell is_a: CL:1000615 ! kidney cortex tubule cell relationship: part_of UBERON:0004135 ! distal tubule [Term] id: CL:0002306 name: epithelial cell of proximal tubule namespace: cell def: "An epithelial cell of the proximal tubule of the kidney." [] synonym: "kidney proximal tubule epithelial cell" EXACT [] xref: FMA:62125 xref: FMA:70973 xref: KUPO:0001044 is_a: CL:1000494 ! nephron tubule epithelial cell is_a: CL:1000615 ! kidney cortex tubule cell relationship: part_of UBERON:0004134 ! proximal tubule [Term] id: CL:0002307 name: brush border cell of the proximal tubule namespace: cell def: "A brush border epithelial cell located in the proximal tubule of the kidney that detects fluid flow." [] is_a: CL:0002306 ! epithelial cell of proximal tubule created_by: tmeehan creation_date: 2010-09-14T11:29:20Z [Term] id: CL:0002518 name: kidney epithelial cell namespace: cell def: "An epithelial cell of the kidney." [] xref: KUPO:0001019 is_a: CL:1000497 ! kidney cell created_by: tmeehan creation_date: 2011-02-08T10:46:34Z [Term] id: CL:0002519 name: interrenal epithelial cell namespace: cell def: "An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type." [] is_a: CL:0002518 ! kidney epithelial cell created_by: tmeehan creation_date: 2011-02-08T11:03:32Z [Term] id: CL:0002520 name: nephrocyte namespace: cell def: "An insect excretory cell that regulates haemolymph composition by filtration and filtrate endocytosis." [] xref: BTO:0004597 xref: FMA:83807 is_a: CL:0002522 ! renal filtration cell created_by: tmeehan creation_date: 2011-02-08T01:34:56Z [Term] id: CL:0002522 name: renal filtration cell namespace: cell def: "A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both." [] relationship: part_of UBERON:0001008 ! renal system created_by: tmeehan creation_date: 2011-02-08T01:37:59Z [Term] id: CL:0002523 name: mesonephric glomerular visceral epithelial cell namespace: cell def: "A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros" [] is_a: CL:0000653 ! glomerular visceral epithelial cell relationship: part_of UBERON:0000080 ! mesonephros created_by: tmeehan creation_date: 2011-02-08T01:58:30Z [Term] id: CL:0002524 name: disseminated nephrocyte namespace: cell def: "A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues." [] is_a: CL:0002520 ! nephrocyte created_by: tmeehan creation_date: 2011-02-08T02:07:33Z [Term] id: CL:0002525 name: metanephric glomerular visceral epithelial cell namespace: cell def: "A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the metanephros." [] is_a: CL:0000653 ! glomerular visceral epithelial cell relationship: part_of UBERON:0000081 ! metanephros created_by: tmeehan creation_date: 2011-02-08T02:02:13Z [Term] id: CL:0002584 name: renal cortical epithelial cell namespace: cell def: "An epithelial cell of the kidney cortex." [] xref: KUPO:0001016 is_a: CL:0002518 ! kidney epithelial cell is_a: CL:0002681 ! kidney cortical cell [Term] id: CL:0002597 name: smooth muscle cell of bladder namespace: cell def: "A smooth muscle cell of the bladder." [] xref: KUPO:0001122 is_a: CL:1001319 ! bladder cell created_by: tmeehan creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002681 name: kidney cortical cell namespace: cell is_a: CL:1000497 ! kidney cell relationship: part_of UBERON:0001225 ! cortex of kidney created_by: terryh creation_date: 2011-10-25T03:49:41Z [Term] id: CL:0005009 name: renal principal cell namespace: cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the cells apical membrane is regulated by aldosterone and vasopressin. In mammals these cells are located in the renal collecting ducts." [] is_a: CL:0002518 ! kidney epithelial cell [Term] id: CL:0005010 name: renal intercalated cell namespace: cell def: "A cuboidal epithelial cell of the kidney that regulates acid/base balance." [] synonym: "intercalated cell" EXACT [] xref: FMA:86560 is_a: CL:0002518 ! kidney epithelial cell [Term] id: CL:0005011 name: renal alpha-intercalated cell namespace: cell def: "A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance." [] is_a: CL:0005010 ! renal intercalated cell [Term] id: CL:0009019 name: nephrogenic zone cell def: "A kidney cortical cell that is part of the nephrogenic zone." [] synonym: "cortical nephrogenic niche cell" EXACT [] synonym: "cortical nephrogenic zone cell" EXACT [] xref: https://orcid.org/0000-0002-3163-0115 xref: PMID:29449449 is_a: CL:0002681 ! kidney cortical cell relationship: part_of UBERON:0009871 ! nephrogenic zone created_by: http://orcid.org/0000-0002-2825-0621 [Term] id: CL:1000022 name: mesonephric nephron tubule epithelial cell is_a: CL:1000507 ! kidney tubule cell relationship: part_of UBERON:0005329 ! mesonephric nephron tubule [Term] id: CL:1000090 name: pronephric nephron tubule epithelial cell is_a: CL:1000507 ! kidney tubule cell relationship: part_of UBERON:0005310 ! pronephric nephron tubule [Term] id: CL:1000123 name: metanephric nephron tubule epithelial cell is_a: CL:1000507 ! kidney tubule cell relationship: part_of UBERON:0005146 ! metanephric nephron tubule [Term] id: CL:1000155 name: Malpighian tubule stellate cell def: "A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium." [] synonym: "Malpighian tubule Type II cell" EXACT [] xref: FBbt:00005797 relationship: part_of UBERON:0001054 ! Malpighian tubule [Term] id: CL:1000182 name: malpighian tubule tip cell relationship: part_of UBERON:0001054 ! Malpighian tubule [Term] id: CL:1000296 name: epithelial cell of urethra namespace: cell def: "An epithelial cell that is part of the urethra." [] xref: FMA:256165 is_a: CL:1001320 ! urethra cell [Term] id: CL:1000308 name: fibrocyte of adventitia of ureter namespace: cell def: "A fibrocyte that is part of the adventitia of ureter." [] xref: FMA:261289 is_a: CL:1000708 ! ureter adventitial cell [Term] id: CL:1000442 name: urothelial cell of trigone of urinary bladder namespace: cell def: "An urothelial cell that is part of the trigone of urinary bladder." [] synonym: "epithelial cell of vesical trigone" EXACT [] xref: FMA:70598 is_a: CL:0000731 ! urothelial cell is_a: CL:1001319 ! bladder cell relationship: part_of UBERON:0001257 ! trigone of urinary bladder [Term] id: CL:1000449 name: epithelial cell of nephron namespace: cell def: "An epithelial cell that is part of the nephron." [] xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell relationship: part_of UBERON:0001285 ! nephron [Term] id: CL:1000450 name: epithelial cell of glomerular capsule namespace: cell def: "An epithelial cell that is part of the glomerular capsule." [] synonym: "Bowmans capsule epithelial cell" EXACT [] synonym: "epithelial cell of Bowman's capsule" EXACT [] xref: FMA:70966 xref: KUPO:0001034 is_a: CL:1000510 ! kidney glomerular epithelial cell relationship: part_of UBERON:0001230 ! glomerular capsule [Term] id: CL:1000452 name: parietal epithelial cell namespace: cell alt_id: CL:1000897 def: "An epithelial cell that is part of the glomerular parietal epithelium." [] synonym: "epithelial cell of parietal layer of glomerular capsule" EXACT [] xref: FMA:70968 xref: KUPO:0001035 is_a: CL:1000450 ! epithelial cell of glomerular capsule relationship: part_of UBERON:0005750 ! glomerular parietal epithelium [Term] id: CL:1000453 name: epithelial cell of intermediate tubule namespace: cell def: "An epithelial cell that is part of the intermediate tubule." [] xref: FMA:70980 is_a: CL:1000909 ! kidney loop of Henle epithelial cell relationship: part_of UBERON:0004136 ! intermediate tubule [Term] id: CL:1000454 name: kidney collecting duct epithelial cell namespace: cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [] synonym: "epithelial cell of renal collecting tubule" EXACT [] xref: FMA:70982 xref: KUPO:0001059 is_a: CL:1001225 ! kidney collecting duct cell [Term] id: CL:1000486 name: basal cell of urothelium namespace: cell def: "A basal cell that is part of the urothelium." [] xref: FMA:84150 relationship: part_of UBERON:0000365 ! urothelium [Term] id: CL:1000494 name: nephron tubule epithelial cell namespace: cell def: "An epithelial cell that is part of a nephron tubule." [] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 is_a: CL:1000507 ! kidney tubule cell relationship: part_of UBERON:0004810 ! nephron tubule epithelium [Term] id: CL:1000497 name: kidney cell namespace: cell xref: KUPO:0001010 relationship: part_of UBERON:0002113 ! kidney [Term] id: CL:1000500 name: kidney interstitial cell namespace: cell xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell relationship: part_of UBERON:0005215 ! kidney interstitium [Term] id: CL:1000504 name: kidney medulla cell namespace: cell xref: KUPO:0001017 is_a: CL:1000497 ! kidney cell relationship: part_of UBERON:0000362 ! renal medulla [Term] id: CL:1000505 name: kidney pelvis cell namespace: cell xref: KUPO:0001018 is_a: CL:1000497 ! kidney cell relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: CL:1000507 name: kidney tubule cell namespace: cell xref: KUPO:0001020 is_a: CL:1000449 ! epithelial cell of nephron relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000510 name: kidney glomerular epithelial cell namespace: cell xref: KUPO:0001023 is_a: CL:1000746 ! glomerular cell relationship: part_of UBERON:0004188 ! glomerular epithelium [Term] id: CL:1000546 name: kidney medulla collecting duct epithelial cell namespace: cell xref: KUPO:0001060 is_a: CL:1000504 ! kidney medulla cell is_a: CL:1001225 ! kidney collecting duct cell relationship: part_of UBERON:0005185 ! renal medulla collecting duct [Term] id: CL:1000547 name: kidney inner medulla collecting duct epithelial cell namespace: cell xref: KUPO:0001061 is_a: CL:1000617 ! kidney inner medulla cell is_a: CL:1001225 ! kidney collecting duct cell relationship: part_of UBERON:0004205 ! inner medullary collecting duct [Term] id: CL:1000548 name: kidney outer medulla collecting duct epithelial cell namespace: cell xref: KUPO:0001062 is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001225 ! kidney collecting duct cell relationship: part_of UBERON:0004204 ! outer medullary collecting duct [Term] id: CL:1000549 name: kidney cortex collecting duct epithelial cell namespace: cell xref: KUPO:0001063 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1001225 ! kidney collecting duct cell relationship: part_of UBERON:0004203 ! cortical collecting duct [Term] id: CL:1000550 name: kidney papillary duct principal epithelial cell namespace: cell xref: KUPO:0001064 is_a: CL:1001225 ! kidney collecting duct cell relationship: part_of UBERON:0005167 ! papillary duct [Term] id: CL:1000596 name: inner renal cortex cell namespace: cell xref: KUPO:0001111 is_a: CL:0002681 ! kidney cortical cell relationship: part_of UBERON:0005271 ! juxtamedullary cortex [Term] id: CL:1000597 name: papillary tips cell namespace: cell xref: KUPO:0001112 is_a: CL:1000505 ! kidney pelvis cell is_a: CL:1000617 ! kidney inner medulla cell relationship: part_of UBERON:0009095 ! tip of renal papilla [Term] id: CL:1000600 name: lower urinary tract cell namespace: cell xref: KUPO:0001115 relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: CL:1000601 name: ureteral cell namespace: cell xref: KUPO:0001116 relationship: part_of UBERON:0000056 ! ureter [Term] id: CL:1000606 name: kidney nerve cell namespace: cell xref: KUPO:0001015 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000612 name: kidney corpuscule cell namespace: cell xref: KUPO:0001021 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000449 ! epithelial cell of nephron relationship: part_of UBERON:0001229 ! renal corpuscle [Term] id: CL:1000615 name: kidney cortex tubule cell namespace: cell xref: KUPO:0001024 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000507 ! kidney tubule cell relationship: part_of UBERON:0006853 ! renal cortex tubule [Term] id: CL:1000616 name: kidney outer medulla cell namespace: cell xref: KUPO:0001025 is_a: CL:1000504 ! kidney medulla cell relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: CL:1000617 name: kidney inner medulla cell namespace: cell xref: KUPO:0001026 is_a: CL:1000504 ! kidney medulla cell relationship: part_of UBERON:0001294 ! inner medulla of kidney [Term] id: CL:1000618 name: juxtaglomerular complex cell namespace: cell synonym: "juxtaglomerulus cell" EXACT [] xref: KUPO:0001028 is_a: CL:0002681 ! kidney cortical cell relationship: part_of UBERON:0002303 ! juxtaglomerular apparatus [Term] id: CL:1000681 name: kidney cortex interstitial cell namespace: cell xref: KUPO:0001091 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000500 ! kidney interstitial cell relationship: part_of UBERON:0005270 ! renal cortex interstitium [Term] id: CL:1000682 name: kidney medulla interstitial cell namespace: cell xref: KUPO:0001092 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:1000504 ! kidney medulla cell relationship: part_of UBERON:0005211 ! renal medulla interstitium [Term] id: CL:1000691 name: kidney interstitial myofibroblast namespace: cell xref: KUPO:0001101 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000692 name: kidney interstitial fibroblast namespace: cell xref: KUPO:0001102 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000693 name: kidney interstitial fibrocyte namespace: cell xref: KUPO:0001103 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000695 name: kidney interstitial alternatively activated macrophage namespace: cell xref: KUPO:0001106 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000696 name: kidney interstitial inflammatory macrophage namespace: cell xref: KUPO:0001107 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000697 name: kidney interstitial suppressor macrophage namespace: cell xref: KUPO:0001108 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000698 name: kidney resident macrophage namespace: cell xref: KUPO:0001109 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000699 name: kidney resident dendritic cell namespace: cell xref: KUPO:0001110 is_a: CL:1000500 ! kidney interstitial cell [Term] id: CL:1000702 name: kidney pelvis smooth muscle cell namespace: cell xref: KUPO:0001113 is_a: CL:1000505 ! kidney pelvis cell relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle [Term] id: CL:1000703 name: kidney pelvis urothelial cell namespace: cell xref: KUPO:0001114 is_a: CL:0000731 ! urothelial cell is_a: CL:0002518 ! kidney epithelial cell is_a: CL:1000505 ! kidney pelvis cell relationship: part_of UBERON:0004788 ! kidney pelvis urothelium [Term] id: CL:1000706 name: ureter urothelial cell namespace: cell xref: KUPO:0001117 is_a: CL:0000731 ! urothelial cell is_a: CL:1000601 ! ureteral cell relationship: part_of UBERON:0001254 ! urothelium of ureter [Term] id: CL:1000708 name: ureter adventitial cell namespace: cell xref: KUPO:0001119 is_a: CL:1000601 ! ureteral cell relationship: part_of UBERON:0001252 ! adventitia of ureter [Term] id: CL:1000714 name: kidney cortex collecting duct principal cell namespace: cell xref: KUPO:0001130 is_a: CL:1000549 ! kidney cortex collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell [Term] id: CL:1000715 name: kidney cortex collecting duct intercalated cell namespace: cell xref: KUPO:0001131 is_a: CL:1000549 ! kidney cortex collecting duct epithelial cell is_a: CL:1001432 ! kidney collecting duct intercalated cell [Term] id: CL:1000716 name: kidney outer medulla collecting duct principal cell namespace: cell xref: KUPO:0001132 is_a: CL:1000548 ! kidney outer medulla collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell [Term] id: CL:1000717 name: kidney outer medulla collecting duct intercalated cell namespace: cell xref: KUPO:0001133 is_a: CL:1000548 ! kidney outer medulla collecting duct epithelial cell is_a: CL:1001432 ! kidney collecting duct intercalated cell [Term] id: CL:1000718 name: kidney inner medulla collecting duct principal cell namespace: cell xref: KUPO:0001134 is_a: CL:1000547 ! kidney inner medulla collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell [Term] id: CL:1000719 name: kidney inner medulla collecting duct intercalated cell namespace: cell xref: KUPO:0001135 is_a: CL:1000547 ! kidney inner medulla collecting duct epithelial cell is_a: CL:1001432 ! kidney collecting duct intercalated cell [Term] id: CL:1000720 name: kidney papillary duct intercalated cell namespace: cell xref: KUPO:0001136 is_a: CL:1000550 ! kidney papillary duct principal epithelial cell is_a: CL:1001432 ! kidney collecting duct intercalated cell [Term] id: CL:1000721 name: kidney papillary duct principal cell namespace: cell xref: KUPO:0001137 is_a: CL:1000550 ! kidney papillary duct principal epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell [Term] id: CL:1000742 name: glomerular mesangial cell namespace: cell def: "Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney." [] synonym: "intraglomerular mesangial cell" EXACT [] xref: KUPO:0001032 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:1000746 ! glomerular cell is_a: CL:1001318 ! renal interstitial pericyte relationship: part_of UBERON:0002320 ! glomerular mesangium [Term] id: CL:1000746 name: glomerular cell namespace: cell xref: KUPO:0001036 is_a: CL:1000612 ! kidney corpuscule cell relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: CL:1000768 name: kidney connecting tubule epithelial cell namespace: cell xref: KUPO:0001058 is_a: CL:1000494 ! nephron tubule epithelial cell is_a: CL:1000615 ! kidney cortex tubule cell relationship: part_of UBERON:0005097 ! renal connecting tubule [Term] id: CL:1000803 name: kidney inner medulla interstitial cell namespace: cell xref: KUPO:0001093 is_a: CL:1000617 ! kidney inner medulla cell is_a: CL:1000682 ! kidney medulla interstitial cell relationship: part_of UBERON:0005214 ! inner renal medulla interstitium [Term] id: CL:1000804 name: kidney outer medulla interstitial cell namespace: cell xref: KUPO:0001094 is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1000682 ! kidney medulla interstitial cell relationship: part_of UBERON:0005213 ! outer renal medulla interstitium [Term] id: CL:1000838 name: kidney proximal convoluted tubule epithelial cell namespace: cell xref: KUPO:0001045 is_a: CL:0002306 ! epithelial cell of proximal tubule relationship: part_of UBERON:0001287 ! proximal convoluted tubule [Term] id: CL:1000839 name: kidney proximal straight tubule epithelial cell namespace: cell xref: KUPO:0001046 is_a: CL:0002306 ! epithelial cell of proximal tubule is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001021 ! kidney loop of Henle descending limb epithelial cell relationship: part_of UBERON:0001290 ! proximal straight tubule [Term] id: CL:1000849 name: kidney distal convoluted tubule epithelial cell namespace: cell xref: KUPO:0001056 is_a: CL:0002305 ! epithelial cell of distal tubule relationship: part_of UBERON:0001292 ! distal convoluted tubule [Term] id: CL:1000850 name: macula densa epithelial cell namespace: cell xref: KUPO:0001057 is_a: CL:0002305 ! epithelial cell of distal tubule is_a: CL:1000618 ! juxtaglomerular complex cell relationship: part_of UBERON:0002335 ! macula densa [Term] id: CL:1000854 name: kidney blood vessel cell namespace: cell xref: KUPO:0001014 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000504 ! kidney medulla cell relationship: part_of UBERON:0003517 ! kidney blood vessel [Term] id: CL:1000891 name: kidney arterial blood vessel cell namespace: cell xref: KUPO:0001029 is_a: CL:1000854 ! kidney blood vessel cell relationship: part_of UBERON:0003644 ! kidney arterial blood vessel [Term] id: CL:1000892 name: kidney capillary endothelial cell namespace: cell xref: KUPO:0001030 is_a: CL:1000854 ! kidney blood vessel cell relationship: part_of UBERON:0003527 ! kidney capillary [Term] id: CL:1000893 name: kidney venous blood vessel cell namespace: cell xref: KUPO:0001031 is_a: CL:1000854 ! kidney blood vessel cell [Term] id: CL:1000909 name: kidney loop of Henle epithelial cell namespace: cell xref: KUPO:0001047 is_a: CL:1000494 ! nephron tubule epithelial cell relationship: part_of UBERON:0001288 ! loop of Henle [Term] id: CL:1000979 name: ureter smooth muscle cell namespace: cell xref: KUPO:0001118 is_a: CL:1000601 ! ureteral cell relationship: part_of UBERON:0006855 ! muscular coat of ureter [Term] id: CL:1001005 name: glomerular capillary endothelial cell namespace: cell xref: KUPO:0001037 is_a: CL:0002188 ! glomerular endothelial cell is_a: CL:1000510 ! kidney glomerular epithelial cell is_a: CL:1000892 ! kidney capillary endothelial cell relationship: part_of UBERON:0004294 ! glomerular capillary endothelium [Term] id: CL:1001006 name: kidney afferent arteriole cell namespace: cell xref: KUPO:0001038 is_a: CL:1000612 ! kidney corpuscule cell is_a: CL:1000891 ! kidney arterial blood vessel cell relationship: part_of UBERON:0004639 ! renal afferent arteriole [Term] id: CL:1001009 name: kidney efferent arteriole cell namespace: cell xref: KUPO:0001041 is_a: CL:1000612 ! kidney corpuscule cell is_a: CL:1000891 ! kidney arterial blood vessel cell relationship: part_of UBERON:0004640 ! renal efferent arteriole [Term] id: CL:1001016 name: kidney loop of Henle ascending limb epithelial cell namespace: cell xref: KUPO:0001048 is_a: CL:0002305 ! epithelial cell of distal tubule is_a: CL:1000909 ! kidney loop of Henle epithelial cell relationship: part_of UBERON:0005164 ! ascending limb of loop of Henle [Term] id: CL:1001021 name: kidney loop of Henle descending limb epithelial cell namespace: cell xref: KUPO:0001053 is_a: CL:1000909 ! kidney loop of Henle epithelial cell relationship: part_of UBERON:0001289 ! descending limb of loop of Henle [Term] id: CL:1001033 name: peritubular capillary endothelial cell namespace: cell xref: KUPO:0001065 is_a: CL:1000892 ! kidney capillary endothelial cell relationship: part_of UBERON:0005272 ! peritubular capillary [Term] id: CL:1001036 name: vasa recta cell namespace: cell xref: KUPO:0001068 is_a: CL:1000892 ! kidney capillary endothelial cell is_a: CL:1000893 ! kidney venous blood vessel cell [Term] id: CL:1001045 name: kidney cortex artery cell namespace: cell xref: KUPO:0001077 is_a: CL:1000891 ! kidney arterial blood vessel cell relationship: part_of UBERON:0005268 ! renal cortex artery [Term] id: CL:1001052 name: kidney cortex vein cell namespace: cell xref: KUPO:0001084 is_a: CL:1000893 ! kidney venous blood vessel cell relationship: part_of UBERON:0005269 ! renal cortex vein [Term] id: CL:1001064 name: kidney artery smooth muscle cell namespace: cell comment: Note that the source of this term is KUPO:0001096 (artery smooth muscle cell), which we believe actually denotes the kidney specific structure. xref: KUPO:0001096 is_a: CL:1000891 ! kidney arterial blood vessel cell [Term] id: CL:1001066 name: kidney arteriole smooth muscle cell namespace: cell comment: Note that the source of this term is KUPO:0001098 (arteriole smooth muscle cell), which we believe actually denotes the kidney specific structure. xref: KUPO:0001098 is_a: CL:1000891 ! kidney arterial blood vessel cell [Term] id: CL:1001068 name: kidney venous system smooth muscle cell namespace: cell comment: Note that the source of this term is KUPO:0001068 (venous system smooth muscle cell), which we believe actually denotes the kidney specific structure. xref: KUPO:0001100 is_a: CL:1000893 ! kidney venous blood vessel cell [Term] id: CL:1001096 name: kidney afferent arteriole endothelial cell namespace: cell xref: KUPO:0001039 is_a: CL:1001006 ! kidney afferent arteriole cell is_a: CL:1001216 ! interlobulary artery endothelial cell [Term] id: CL:1001097 name: kidney afferent arteriole smooth muscle cell namespace: cell xref: KUPO:0001040 is_a: CL:1001006 ! kidney afferent arteriole cell is_a: CL:1001066 ! kidney arteriole smooth muscle cell is_a: CL:1001217 ! interlobulary artery smooth muscle cell [Term] id: CL:1001099 name: kidney efferent arteriole endothelial cell namespace: cell xref: KUPO:0001042 is_a: CL:1001009 ! kidney efferent arteriole cell [Term] id: CL:1001100 name: kidney efferent arteriole smooth muscle cell namespace: cell xref: KUPO:0001043 is_a: CL:1001009 ! kidney efferent arteriole cell is_a: CL:1001066 ! kidney arteriole smooth muscle cell [Term] id: CL:1001106 name: kidney loop of Henle thick ascending limb epithelial cell namespace: cell xref: KUPO:0001049 is_a: CL:1000504 ! kidney medulla cell is_a: CL:1001016 ! kidney loop of Henle ascending limb epithelial cell relationship: part_of UBERON:0001291 ! thick ascending limb of loop of Henle [Term] id: CL:1001107 name: kidney loop of Henle thin ascending limb epithelial cell namespace: cell xref: KUPO:0001050 is_a: CL:1000617 ! kidney inner medulla cell is_a: CL:1001016 ! kidney loop of Henle ascending limb epithelial cell relationship: part_of UBERON:0004193 ! loop of Henle ascending limb thin segment [Term] id: CL:1001108 name: kidney loop of Henle medullary thick ascending limb epithelial cell namespace: cell xref: KUPO:0001051 is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001106 ! kidney loop of Henle thick ascending limb epithelial cell relationship: part_of UBERON:0006376 ! premacula segment of distal straight tubule [Term] id: CL:1001109 name: kidney loop of Henle cortical thick ascending limb epithelial cell namespace: cell xref: KUPO:0001052 is_a: CL:1001106 ! kidney loop of Henle thick ascending limb epithelial cell relationship: part_of UBERON:0006854 ! distal straight tubule postmacula segment [Term] id: CL:1001111 name: kidney loop of Henle thin descending limb epithelial cell namespace: cell xref: KUPO:0001054 is_a: CL:1000453 ! epithelial cell of intermediate tubule is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001021 ! kidney loop of Henle descending limb epithelial cell relationship: part_of UBERON:0005096 ! descending thin limb [Term] id: CL:1001123 name: kidney outer medulla peritubular capillary cell namespace: cell xref: KUPO:0001066 is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001033 ! peritubular capillary endothelial cell relationship: part_of UBERON:0006341 ! outer renal medulla peritubular capillary [Term] id: CL:1001124 name: kidney cortex peritubular capillary cell namespace: cell xref: KUPO:0001067 is_a: CL:1001033 ! peritubular capillary endothelial cell relationship: part_of UBERON:0006851 ! renal cortex peritubular capillary [Term] id: CL:1001126 name: inner renal medulla vasa recta cell namespace: cell xref: KUPO:0001069 is_a: CL:1000617 ! kidney inner medulla cell is_a: CL:1001036 ! vasa recta cell relationship: part_of UBERON:0004776 ! inner renal medulla vasa recta [Term] id: CL:1001127 name: outer renal medulla vasa recta cell namespace: cell xref: KUPO:0001070 is_a: CL:1000616 ! kidney outer medulla cell is_a: CL:1001036 ! vasa recta cell relationship: part_of UBERON:0004775 ! outer renal medulla vasa recta [Term] id: CL:1001131 name: vasa recta ascending limb cell namespace: cell xref: KUPO:0001074 is_a: CL:1001036 ! vasa recta cell [Term] id: CL:1001135 name: arcuate artery cell namespace: cell xref: KUPO:0001078 is_a: CL:1001045 ! kidney cortex artery cell relationship: part_of UBERON:0001552 ! kidney arcuate artery [Term] id: CL:1001138 name: interlobular artery cell namespace: cell xref: KUPO:0001081 is_a: CL:1001045 ! kidney cortex artery cell relationship: part_of UBERON:0004723 ! interlobular artery [Term] id: CL:1001142 name: arcuate vein cell namespace: cell xref: KUPO:0001085 is_a: CL:1001052 ! kidney cortex vein cell relationship: part_of UBERON:0004719 ! kidney arcuate vein [Term] id: CL:1001145 name: interlobular vein cell namespace: cell xref: KUPO:0001088 is_a: CL:1001052 ! kidney cortex vein cell relationship: part_of UBERON:0005168 ! renal interlobular vein [Term] id: CL:1001209 name: inner medulla vasa recta ascending limb cell namespace: cell xref: KUPO:0001075 is_a: CL:1001126 ! inner renal medulla vasa recta cell is_a: CL:1001131 ! vasa recta ascending limb cell relationship: part_of UBERON:0009092 ! inner medulla vasa recta ascending limb [Term] id: CL:1001210 name: outer medulla vasa recta ascending limb cell namespace: cell xref: KUPO:0001076 is_a: CL:1001127 ! outer renal medulla vasa recta cell is_a: CL:1001131 ! vasa recta ascending limb cell relationship: part_of UBERON:0009093 ! outer medulla vasa recta ascending limb [Term] id: CL:1001213 name: arcuate artery endothelial cell namespace: cell xref: KUPO:0001079 is_a: CL:1001135 ! arcuate artery cell [Term] id: CL:1001214 name: arcuate artery smooth muscle cell namespace: cell xref: KUPO:0001080 is_a: CL:1001064 ! kidney artery smooth muscle cell is_a: CL:1001135 ! arcuate artery cell [Term] id: CL:1001216 name: interlobulary artery endothelial cell namespace: cell xref: KUPO:0001082 is_a: CL:1001138 ! interlobular artery cell [Term] id: CL:1001217 name: interlobulary artery smooth muscle cell namespace: cell xref: KUPO:0001083 is_a: CL:1001064 ! kidney artery smooth muscle cell is_a: CL:1001138 ! interlobular artery cell [Term] id: CL:1001220 name: arcuate vein endothelial cell namespace: cell xref: KUPO:0001086 is_a: CL:1001142 ! arcuate vein cell [Term] id: CL:1001221 name: arcuate vein smooth muscle cell namespace: cell xref: KUPO:0001087 is_a: CL:1001068 ! kidney venous system smooth muscle cell is_a: CL:1001142 ! arcuate vein cell [Term] id: CL:1001223 name: interlobulary vein endothelial cell namespace: cell xref: KUPO:0001089 is_a: CL:1001145 ! interlobular vein cell [Term] id: CL:1001224 name: interlobulary vein smooth muscle cell namespace: cell xref: KUPO:0001090 is_a: CL:1001068 ! kidney venous system smooth muscle cell is_a: CL:1001145 ! interlobular vein cell [Term] id: CL:1001225 name: kidney collecting duct cell namespace: cell xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000449 ! epithelial cell of nephron relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: CL:1001285 name: vasa recta descending limb cell namespace: cell xref: KUPO:0001071 is_a: CL:1001036 ! vasa recta cell [Term] id: CL:1001286 name: inner medulla vasa recta descending limb cell namespace: cell xref: KUPO:0001072 is_a: CL:1001126 ! inner renal medulla vasa recta cell is_a: CL:1001285 ! vasa recta descending limb cell relationship: part_of UBERON:0009089 ! inner medulla vasa recta descending limb [Term] id: CL:1001287 name: outer medulla vasa recta descending limb cell namespace: cell xref: KUPO:0001073 is_a: CL:1001127 ! outer renal medulla vasa recta cell is_a: CL:1001285 ! vasa recta descending limb cell relationship: part_of UBERON:0009090 ! outer medulla vasa recta descending limb [Term] id: CL:1001318 name: renal interstitial pericyte namespace: cell xref: KUPO:0001104 is_a: CL:1000497 ! kidney cell [Term] id: CL:1001319 name: bladder cell namespace: cell xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: CL:1001320 name: urethra cell namespace: cell xref: KUPO:0001123 is_a: CL:1000600 ! lower urinary tract cell relationship: part_of UBERON:0000057 ! urethra [Term] id: CL:1001428 name: bladder urothelial cell namespace: cell xref: KUPO:0001121 is_a: CL:0000731 ! urothelial cell is_a: CL:1001319 ! bladder cell relationship: part_of UBERON:0004645 ! urinary bladder urothelium [Term] id: CL:1001430 name: urethra urothelial cell namespace: cell xref: KUPO:0001124 is_a: CL:0000731 ! urothelial cell is_a: CL:1000296 ! epithelial cell of urethra relationship: part_of UBERON:0004787 ! urethra urothelium [Term] id: CL:1001431 name: kidney collecting duct principal cell namespace: cell xref: KUPO:0001128 is_a: CL:0005009 ! renal principal cell is_a: CL:1000454 ! kidney collecting duct epithelial cell [Term] id: CL:1001432 name: kidney collecting duct intercalated cell namespace: cell xref: http://en.wikipedia.org/wiki/Collecting_duct_system#Intercalated_cells xref: KUPO:0001129 is_a: CL:0005010 ! renal intercalated cell is_a: CL:1000454 ! kidney collecting duct epithelial cell [Term] id: CL:2000040 name: bladder microvascular endothelial cell namespace: cell def: "Any microvascular endothelial cell that is part of a urinary bladder." [] is_a: CL:1001319 ! bladder cell created_by: TermGenie creation_date: 2014-07-09T00:04:47Z [Term] id: CL:2000065 name: ovarian microvascular endothelial cell namespace: cell def: "Any microvascular endothelial cell that is part of a female urethra." [] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7300 is_a: CL:1000296 ! epithelial cell of urethra relationship: part_of UBERON:0001334 ! female urethra created_by: TermGenie creation_date: 2014-10-07T18:18:01Z [Term] id: UBERON:0000056 name: ureter namespace: uberon def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs." [GO:0090189, http://en.wikipedia.org/wiki/Ureter] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "metanephric duct" RELATED [ISBN:0073040584, VHOG:0000605] xref: AAO:0010254 xref: BTO:0001409 xref: CALOHA:TS-1084 xref: EFO:0000930 xref: EHDAA2:0002139 xref: EHDAA:9341 xref: EMAPA:17950 xref: EV:0100097 xref: FMA:9704 xref: GAID:438 xref: galen:Ureter xref: http://en.wikipedia.org/wiki/Ureter xref: http://linkedlifedata.com/resource/umls/id/C0041951 xref: http://www.snomedbrowser.com/Codes/Details/302511008 xref: MA:0000378 xref: MAT:0000120 xref: MESH:D014513 xref: MIAA:0000120 xref: NCIT:C12416 xref: OpenCyc:Mx4rvhmm6JwpEbGdrcN5Y29ycA xref: UMLS:C0041951 {source="ncithesaurus:Ureter"} xref: VHOG:0000605 xref: XAO:0000144 is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0036295 ! renal pelvis/ureter property_value: depicted:by Urinary:system.svg xsd:anyURI property_value: UBPROP:0000001 "Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010254", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543"} property_value: UBPROP:0000007 "ureteral" xsd:string property_value: UBPROP:0000007 "ureteric" xsd:string property_value: UBPROP:0000010 "in humans, consists of adventitial, muscular and mucoa layers" xsd:string [Term] id: UBERON:0000057 name: urethra namespace: uberon def: "the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening" [MGI:anna, MP:0000537] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001426 xref: CALOHA:TS-1132 xref: EFO:0000931 xref: EMAPA:30901 xref: EV:0100099 xref: FMA:19667 xref: GAID:390 xref: galen:Urethra xref: http://en.wikipedia.org/wiki/Urethra xref: http://linkedlifedata.com/resource/umls/id/C0041967 xref: http://www.snomedbrowser.com/Codes/Details/302513006 xref: MA:0000379 xref: MAT:0000121 xref: MESH:D014521 xref: MIAA:0000121 xref: NCIT:C12417 xref: OpenCyc:Mx4rvVjkypwpEbGdrcN5Y29ycA xref: UMLS:C0041967 {source="ncithesaurus:Urethra"} xref: VHOG:0001264 xref: XAO:0000153 relationship: part_of UBERON:0001556 ! lower urinary tract property_value: depicted:by Female:anatomy.png xsd:anyURI property_value: UBPROP:0000007 "urethral" xsd:string property_value: UBPROP:0000008 "In human males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening." xsd:string [Term] id: UBERON:0000061 name: anatomical structure namespace: uberon def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003] subset: upper_level synonym: "biological structure" EXACT [] synonym: "connected biological structure" EXACT [CARO:0000003] xref: AAO:0010825 xref: AEO:0000003 xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 xref: FBbt:00007001 xref: FMA:305751 xref: FMA:67135 xref: GAID:781 xref: HAO:0000003 xref: http://dbpedia.org/ontology/AnatomicalStructure xref: http://www.snomedbrowser.com/Codes/Details/362889002 xref: MA:0003000 xref: MESH:D000825 xref: TAO:0000037 xref: TGMA:0001823 xref: VHOG:0001759 xref: XAO:0003000 xref: ZFA:0000037 is_a: UBERON:0000465 ! material anatomical entity [Term] id: UBERON:0000074 name: renal glomerulus namespace: uberon def: "A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [http://en.wikipedia.org/wiki/Glomerulus, MP:0005325] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "glomerular capillary tuft" RELATED [ZFA:0001288] synonym: "glomerular tuft" RELATED INCONSISTENT [] synonym: "glomerulus" BROAD [] synonym: "glomerulus renis" RELATED LATIN [http://en.wikipedia.org/wiki/Glomerulus] synonym: "Malphigian glomerulus" RELATED MISSPELLING [BTO:0000530] synonym: "Malpighian glomerulus" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] synonym: "Malpighian tuft" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] synonym: "renal corpuscle" RELATED INCONSISTENT [] synonym: "renal glomeruli" EXACT [TAO:0001288] xref: BTO:0000530 xref: CALOHA:TS-0862 xref: EFO:0003667 xref: EMAPA:28329 xref: EV:0100386 xref: FMA:15624 xref: http://en.wikipedia.org/wiki/Glomerulus xref: http://linkedlifedata.com/resource/umls/id/C0022663 xref: http://www.snomedbrowser.com/Codes/Details/362217000 xref: MA:0001657 xref: MESH:D007678 xref: NCIT:C13250 xref: TAO:0001288 xref: UMLS:C0022663 {source="ncithesaurus:Glomerulus"} xref: ZFA:0001288 relationship: part_of UBERON:0001229 {source="FMA", source="MA"} ! renal corpuscle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg xsd:anyURI property_value: depicted:by Renal:corpuscle.svg xsd:anyURI property_value: UBPROP:0000012 "ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. GUDMAP: 'Together, the Bowman's capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule?" xsd:string {external_ontology="ZFA"} created_by: Melissa Haendel creation_date: 2009-06-18T09:26:37Z [Term] id: UBERON:0000080 name: mesonephros namespace: uberon def: "The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, http://en.wikipedia.org/wiki/Mesonephros] subset: efo_slim subset: organ_slim subset: pheno_slim subset: vertebrate_core synonym: "amphibian adult kidney" RELATED [XAO:0000141] synonym: "corpus Wolffi" RELATED [BTO:0001542] synonym: "mesonephric kidney" EXACT [XAO:0000141] synonym: "mesonephroi" EXACT PLURAL [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "middle kidney" RELATED [BTO:0001542] synonym: "opisthonephros" RELATED [VHOG:0000038, XAO:0000141] synonym: "opisto nephros" RELATED [] synonym: "opistonephros" RELATED [http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html] synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, http://en.wikipedia.org/wiki/Mesonephros, MESH:A16.254.500] xref: AAO:0010384 xref: BTO:0001542 xref: CALOHA:TS-0624 xref: EFO:0000928 xref: EHDAA2:0001130 xref: EHDAA:1581 xref: EHDAA:5903 xref: EMAPA:16744 xref: FMA:72171 xref: GAID:1308 xref: http://en.wikipedia.org/wiki/Mesonephros xref: http://linkedlifedata.com/resource/umls/id/C0025492 xref: http://www.snomedbrowser.com/Codes/Details/308799002 xref: MESH:D001755 xref: NCIT:C26467 xref: TAO:0000529 xref: UMLS:C0025492 {source="ncithesaurus:Mesonephros"} xref: VHOG:0000038 xref: XAO:0000141 xref: ZFA:0000529 is_a: UBERON:0002113 ! kidney property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png xsd:anyURI property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the middle region of the nephric ridge; a transient embryonic stage that replaces the pronephros, but is itself replaced by the adult metanephros [in mammals; in fishes and amphibians it is the adult kidney]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010384", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates. (...) In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639"} property_value: UBPROP:0000007 "mesonephric" xsd:string property_value: UBPROP:0000008 "In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In fish and amphibians, the mesonephros will form the mature kidney" xsd:string property_value: UBPROP:0000009 "By contrast to the pronephros, the histological features of the mammalian mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP, modified]" xsd:string [Term] id: UBERON:0000081 name: metanephros namespace: uberon def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]" [GO:0001656, http://en.wikipedia.org/wiki/Metanephros#Metanephros] subset: organ_slim subset: pheno_slim synonym: "definite kidney" RELATED [BTO:0001543] synonym: "definitive kidney" RELATED [BTO:0001543] synonym: "hind kidney" RELATED [BTO:0001543] synonym: "metanephric kidney" RELATED [VHOG:0000039] synonym: "metanephron" EXACT [BTO:0001543] xref: BTO:0001543 xref: EHDAA2:0001137 xref: EHDAA:3089 xref: EHDAA:5911 xref: EMAPA:17373 xref: EMAPA_RETIRED:17207 xref: FMA:72172 xref: http://linkedlifedata.com/resource/umls/id/C0231049 xref: http://www.snomedbrowser.com/Codes/Details/308797000 xref: Metanephros xref: NCIT:C34209 xref: UMLS:C0231049 {source="ncithesaurus:Metanephros"} xref: VHOG:0000039 is_a: UBERON:0002113 ! kidney property_value: IAO:0000116 "TODO check developmental relationships" xsd:string property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the posterior region of the nephric ridge and drained by a ureter; replaces the embryonic pronephros and mesonephros [in mammals]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543"} property_value: UBPROP:0000007 "metanephric" xsd:string property_value: UBPROP:0000011 "During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, the metanephric duct, later forms the ureter. As the cranial end of the bud extends into the intermediate mesoderm, it undergoes a series of branchings to form the collecting duct system of the kidney. It also forms the major and minor calyces and the renal pelvis" xsd:string [Term] id: UBERON:0000082 name: adult mammalian kidney namespace: uberon def: "A kidney at the most advanced stage of development in a mammal." [http://en.wikipedia.org/wiki/Kidney_development, https://github.com/obophenotype/uberon/issues/1232] xref: BTO:0000671 xref: CALOHA:TS-0510 xref: EFO:0000929 xref: EV:0100096 xref: FMA:7203 xref: GAID:423 xref: galen:Kidney xref: http://www.snomedbrowser.com/Codes/Details/181414000 xref: MA:0000368 xref: MAT:0000119 xref: MESH:D007668 xref: MIAA:0000119 xref: NCIT:C12415 xref: OpenCyc:Mx4rvVjlYpwpEbGdrcN5Y29ycA is_a: UBERON:0002113 ! kidney [Term] id: UBERON:0000083 name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [http://en.wikipedia.org/wiki/Mesonephric_tubules] synonym: "renal tubules" RELATED PLURAL [VHOG:0000500] synonym: "tubuli mesonephrici" RELATED LATIN [http://en.wikipedia.org/wiki/Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 xref: Mesonephric:tubules xref: VHOG:0000500 xref: XAO:0000148 is_a: UBERON:0005103 ! mesonephric epithelium is_a: UBERON:0006555 ! excretory tube property_value: IAO:0000116 "TODO check" xsd:string property_value: UBPROP:0000001 "Any of the renal tubules composing the mesonephros. In mammals they function as excretory structures during the early embryonic development but are later incorporated into the reproductive system. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesonephric+tubule"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639"} [Term] id: UBERON:0000084 name: ureteric bud namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]" [http://www.ncbi.nlm.nih.gov/pubmed/19828308, MP:0010979] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] synonym: "diverticulum metanephricum" RELATED LATIN [http://en.wikipedia.org/wiki/Ureteric_bud] synonym: "gemma ureterica" RELATED LATIN [http://en.wikipedia.org/wiki/Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [http://en.wikipedia.org/wiki/Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] synonym: "ureteric diverticulum" RELATED [VHOG:0000541] xref: BTO:0001646 xref: EHDAA2:0002140 xref: EHDAA:3091 xref: EHDAA:5917 xref: EMAPA:17209 xref: http://linkedlifedata.com/resource/umls/id/C1284058 xref: http://www.snomedbrowser.com/Codes/Details/361528000 xref: NCIT:C34207 xref: UMLS:C1284058 {source="ncithesaurus:Metanephric_Diverticulum"} xref: Ureteric:bud xref: VHOG:0000541 is_a: UBERON:0000083 ! mesonephric tubule relationship: part_of UBERON:0003074 ! mesonephric duct property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]." xsd:string {source="VHOG:0000541"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543"} [Term] id: UBERON:0000163 name: embryonic cloaca namespace: uberon def: "endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [http://en.wikipedia.org/wiki/Cloaca_(embryology), MP:0010115] subset: pheno_slim synonym: "cloaca" RELATED SENSU [] xref: Cloaca:(embryology) xref: EHDAA2:0000256 xref: EHDAA:4895 xref: EMAPA:27573 relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system property_value: IAO:0000232 "this class represents the embryonic form of the cloaca, as found in both mammals and non-mammals." xsd:string [Term] id: UBERON:0000164 name: primitive urogenital sinus namespace: uberon def: "the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females" [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/18977204] synonym: "sinus urogenitalis" EXACT LATIN [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 xref: EHDAA:5029 xref: EHDAA:5919 xref: EMAPA:17379 xref: http://en.wikipedia.org/wiki/Definitive_urogenital_sinus xref: http://linkedlifedata.com/resource/umls/id/C0231057 xref: http://www.snomedbrowser.com/Codes/Details/50961009 xref: NCIT:C34322 xref: UMLS:C0231057 {source="ncithesaurus:Urogenital_Sinus"} xref: VHOG:0000414 relationship: part_of UBERON:0000163 {source="MP-def"} ! embryonic cloaca property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png xsd:anyURI property_value: UBPROP:0000001 "The ventral part of the cloaca after its separation from the rectum, giving rise to the lower part of the bladder in both sexes, to the prostatic portion of the male urethra, and to the urethra and vestibule in the female. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urogenital+sinus"} property_value: UBPROP:0000003 "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970)p.388-89 and Figure 300"} property_value: UBPROP:0000013 "the term 'urogenital sinus' may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal" xsd:string {source="MP"} [Term] id: UBERON:0000362 name: renal medulla namespace: uberon def: "the inner portion of the kidney consisting of the renal pyramids" [ISBN:0-683-40008-8, MGI:smb, MP:0003014] subset: pheno_slim synonym: "kidney medulla" EXACT [OBOL:automatic] synonym: "medulla of kidney" EXACT [OBOL:automatic] synonym: "medulla renalis" EXACT LATIN [FMA:74268, FMA:TA] synonym: "medullary pyramids" RELATED PLURAL [FMA:74268] synonym: "pyramides renales" EXACT LATIN [FMA:74268, FMA:TA] synonym: "renal marrow" RELATED [BTO:0001167] synonym: "renal medullae" EXACT PLURAL [FMA:86327] synonym: "renal medullae set" EXACT PLURAL [FMA:86327] synonym: "renal pyramids" EXACT PLURAL [FMA:74268] synonym: "renal pyramids set" EXACT PLURAL [FMA:74268] xref: BTO:0001167 xref: CALOHA:TS-1157 xref: EMAPA:19279 xref: GAID:425 xref: galen:MedullaOfKidney xref: http://linkedlifedata.com/resource/umls/id/C0022664 xref: http://www.snomedbrowser.com/Codes/Details/30737000 xref: MA:0000373 xref: MESH:D007679 xref: NCIT:C12740 xref: Renal:medulla xref: UMLS:C0022664 {source="ncithesaurus:Renal_Medulla"} relationship: part_of UBERON:0002113 ! kidney property_value: depicted:by Illu:kidney.jpg xsd:anyURI property_value: UBPROP:0000010 "The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the arcuate arterioles. The arcuate arterioles each in turn branch into interlobular arterioles, which finally reach the glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum portion of the blood out of the vessel into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the Loop of Henle, and finally leaves the kidney by means of the collecting duct, leading to the renal ureter. The renal medulla contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood. The renal medulla is hypertonic to the filtrate in the nephron and aids in the reabsorption of water" xsd:string [Term] id: UBERON:0000365 name: urothelium namespace: uberon def: "An epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra." [http://en.wikipedia.org/wiki/Urothelium, https://github.com/obophenotype/uberon/issues/92] subset: pheno_slim synonym: "epithelium transitionale" EXACT [FMA:63914] synonym: "transitional epithelium" BROAD INCONSISTENT [] synonym: "transitional epithelium" EXACT [FMA:63914, https://github.com/obophenotype/uberon/issues/92] synonym: "uroepithelium" EXACT [FMA:67695] xref: BTO:0003906 xref: CALOHA:TS-1096 xref: EMAPA:37978 {source="MA:th"} xref: FMA:63914 xref: FMA:67695 xref: GAID:935 xref: http://en.wikipedia.org/wiki/Urothelium xref: http://linkedlifedata.com/resource/umls/id/C0225339 xref: http://linkedlifedata.com/resource/umls/id/C0227598 xref: http://www.snomedbrowser.com/Codes/Details/30117005 xref: http://www.snomedbrowser.com/Codes/Details/57789003 xref: MESH:D019459 xref: NCIT:C12884 xref: NCIT:C13318 xref: Transitional:epithelium xref: UMLS:C0225339 {source="ncithesaurus:Transitional_Epithelium"} xref: UMLS:C0227598 {source="ncithesaurus:Urothelium"} relationship: part_of UBERON:0001008 ! renal system property_value: depicted:by Harnblase:Urothel.png xsd:anyURI property_value: UBPROP:0000007 "urothelial" xsd:string [Term] id: UBERON:0000381 name: urinary bladder detrusor smooth muscle namespace: uberon def: "bundles of smooth muscle fibers forming the muscular wall of the urinary bladder, which are arranged in a longitudinal and a circular layer and, on contraction, serve to expel urine[MP]." [http://en.wikipedia.org/wiki/Detrusor_urinae_muscle, MP:0011774] subset: pheno_slim synonym: "detrusor" EXACT [FMA:68018] synonym: "detrusor muscle" EXACT [BTO:0001453] synonym: "detrusor muscle of bladder" EXACT [EMAPA:28637] synonym: "detrusor smooth muscle" EXACT [] synonym: "detrusor urinae muscle" EXACT [http://en.wikipedia.org/wiki/Detrusor_urinae_muscle] synonym: "muscularis propria" BROAD [http://en.wikipedia.org/wiki/Detrusor_urinae_muscle, ncithesaurus:Muscularis_Propria] synonym: "muscularis propria of the urinary bladder" EXACT [http://en.wikipedia.org/wiki/Detrusor_urinae_muscle] synonym: "musculus detrusor vesicae" EXACT LATIN [FMA:68018, FMA:TA] synonym: "musculus detrusor vesicae urinariae" RELATED LATIN [http://en.wikipedia.org/wiki/Detrusor_urinae_muscle] synonym: "urinary bladder detrusor muscle" EXACT [MA:0001698] synonym: "urinary bladder detrussor smooth muscle" EXACT [MA:0001698] xref: BTO:0001453 xref: EMAPA:28637 xref: FMA:68018 xref: http://en.wikipedia.org/wiki/Detrusor_urinae_muscle xref: http://www.snomedbrowser.com/Codes/Details/279414008 xref: MA:0001698 xref: NCIT:C62404 is_a: UBERON:0004228 ! urinary bladder smooth muscle relationship: part_of UBERON:0012378 {source="FMA"} ! muscle layer of urinary bladder property_value: depicted:by Illu:bladder.jpg xsd:anyURI [Term] id: UBERON:0000461 name: minor vestibular gland namespace: uberon def: "Small mucous glands opening upon the vestibular mucous membrane between the urethral and the vaginal orifice." [BTO:0003116] subset: organ_slim synonym: "glandula vestibular minor" EXACT [FMA:20019] synonym: "glandula vestibulares minor" RELATED [BTO:0003116] synonym: "Guerin's gland" RELATED [BTO:0003116] synonym: "Guérin's gland" RELATED [] synonym: "lesser vestibular gland" EXACT [FMA:20019] synonym: "paraurethral gland" RELATED [BTO:0003116] synonym: "periurethral gland" RELATED [BTO:0003116] synonym: "Schueller's gland" RELATED [BTO:0003116] synonym: "Skene gland" RELATED INCONSISTENT [] synonym: "Skene's gland" RELATED INCONSISTENT [BTO:0003116] synonym: "urethral gland of female urethra" RELATED [BTO:0003116] xref: BTO:0003116 xref: FMA:20019 xref: http://www.snomedbrowser.com/Codes/Details/279869001 xref: NCIT:C61122 is_a: UBERON:0010187 ! female urethral gland property_value: IAO:0000116 "compare with Skene's gland" xsd:string property_value: UBPROP:0000010 "check and part_of relationships to mammalian vulva / urethra" xsd:string [Term] id: UBERON:0000465 name: material anatomical entity namespace: uberon def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737] subset: upper_level xref: AAO:0010264 xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 xref: FBbt:00007016 xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 xref: TGMA:0001826 xref: VHOG:0001721 is_a: BFO:0000040 ! material entity is_a: UBERON:0001062 ! anatomical entity [Term] id: UBERON:0000467 name: anatomical system namespace: uberon def: "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." [CARO:0000011] subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "anatomical systems" RELATED PLURAL [ZFA:0001439] synonym: "body system" EXACT [BIRNLEX:14] synonym: "connected anatomical system" EXACT [CARO:0000011] synonym: "organ system" EXACT [] synonym: "system" BROAD [GO:0048731] xref: AAO:0000007 xref: AEO:0000011 xref: BILA:0000011 xref: BIRNLEX:14 xref: BSA:0000049 xref: CALOHA:TS-2088 xref: CARO:0000011 xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 xref: FBbt:00004856 xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 xref: http://linkedlifedata.com/resource/umls/id/C0460002 xref: http://www.snomedbrowser.com/Codes/Details/278195005 xref: MA:0000003 xref: NCIT:C12919 xref: OpenCyc:Mx4rCWM0QCtDEdyAAADggVbxzQ xref: Organ:system xref: TAO:0001439 xref: TGMA:0001831 xref: UMLS:C0460002 {source="ncithesaurus:Organ_System"} xref: VHOG:0001725 xref: WBbt:0005746 xref: WBbt:0005763 xref: XAO:0003002 xref: ZFA:0001439 is_a: UBERON:0000061 ! anatomical structure property_value: seeAlso EHDAA2:0001330 [Term] id: UBERON:0001008 name: renal system namespace: uberon def: "The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products.." [GO:0072001, https://doi.org/10.1371/journal.pone.0099864] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "excretory system" EXACT [] synonym: "renal or urinary system" RELATED [EHDAA:5901] synonym: "renal system" EXACT [GO:0001977] synonym: "renal/urinary system" RELATED [] synonym: "systema urinaria" EXACT [FMA:7159] synonym: "systema urinarium" EXACT [BTO:0003092] synonym: "urinary system" EXACT [] synonym: "urinary tract" EXACT [] xref: AAO:0010257 xref: BILA:0000015 xref: BTO:0001244 xref: BTO:0003092 xref: CALOHA:TS-1323 xref: EFO:0000803 xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 xref: Excretory:system xref: FBbt:00005056 xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract xref: http://linkedlifedata.com/resource/umls/id/C1508753 xref: http://www.snomedbrowser.com/Codes/Details/362204003 xref: MA:0000325 xref: MAT:0000027 xref: MESH:D014551 xref: MIAA:0000027 xref: NCIT:C12413 xref: TADS:0000162 xref: TAO:0000163 xref: UMLS:C1508753 {source="ncithesaurus:Urinary_System"} xref: VHOG:0000723 xref: WBbt:0005736 xref: XAO:0000143 xref: ZFA:0000163 is_a: UBERON:0000467 ! anatomical system property_value: IAO:0000116 "In various sources such as Encyclopedia Britannica, the excretory and urinary systems are indeed the same system (see wikipedia talk page); we merge two BTO classes here" xsd:string property_value: UBPROP:0000001 "An anatomical system which consists of organs and tissues which produce, store, and excrete urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010257", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Evolution of vertebrate renal anatomy appears quite conservative when compared, for example, to evolution of respiratory and cardiovascular systems in vertebrates. Major anatomical changes in vertebrates kidneys separate those of birds and mammals from kidneys of lower vertebrates. General increase in animal size from fish to mammals is reflected by an increase in total number of nephrons per kidney, rather than by constant change in tubular dimensions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000723", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-3540428541 Kapoor BG, Bhavna Khanna, Ichthyology Handbook (2004) p.406"} property_value: UBPROP:0000008 "In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels" xsd:string {source="GO"} property_value: UBPROP:0000008 "This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans" xsd:string {source="https://doi.org/10.1371/journal.pone.0099864"} [Term] id: UBERON:0001054 name: Malpighian tubule namespace: uberon def: "A tubule that extends from the posterior part of the digestive tract which absorbs solutes, water, and wastes from the surrounding hemolymph. Each tubule consists of a single layer of cells that is closed off at the distal end with the proximal end joining the alimentary canal at the junction between the midgut and hindgut[WP,modified]." [http://en.wikipedia.org/wiki/Malpighian_tubule_system] subset: efo_slim subset: uberon_slim synonym: "Malphigian tube" RELATED MISSPELLING [BTO:0000810] synonym: "Malpighian tube" RELATED [UBERON:cjm] synonym: "tuba Malpighii" RELATED [BTO:0000810] xref: BTO:0000810 xref: EFO:0000243 xref: FBbt:00005786 xref: GAID:1228 xref: http://www.snomedbrowser.com/Codes/Details/41055008 xref: Malpighian:tubule xref: MAT:0000123 xref: MESH:D008317 xref: MIAA:0000123 xref: TADS:0000163 xref: TGMA:0001038 is_a: UBERON:0009773 {source="GO"} ! renal tubule property_value: IAO:0000116 "this will be ceded to the Arthropod Anatomy Ontology" xsd:string property_value: UBPROP:0000008 "It is unclear as to whether the Malpighian tubules of arachnids and those of the Uniramia are homologous or the result of convergent evolution.[Wikipedia:Malpighian_tubule_system]" xsd:string [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] subset: upper_level xref: AAO:0010841 xref: AEO:0000000 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FBbt:10000000 xref: FBbt_root:00000000 xref: FMA:62955 xref: HAO:0000000 xref: http://linkedlifedata.com/resource/umls/id/C1515976 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 is_a: BFO:0000004 ! independent continuant [Term] id: UBERON:0001222 name: right ureter namespace: uberon def: "An ureter that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37373 {source="MA:th"} xref: FMA:15571 xref: http://linkedlifedata.com/resource/umls/id/C0227682 xref: http://www.snomedbrowser.com/Codes/Details/276251000 xref: MA:0001685 xref: NCIT:C49327 xref: UMLS:C0227682 {source="ncithesaurus:Right_Ureter"} is_a: UBERON:0000056 ! ureter property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI [Term] id: UBERON:0001223 name: left ureter namespace: uberon def: "An ureter that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37372 {source="MA:th"} xref: FMA:15572 xref: http://linkedlifedata.com/resource/umls/id/C0227683 xref: http://www.snomedbrowser.com/Codes/Details/276340002 xref: MA:0001684 xref: NCIT:C49324 xref: UMLS:C0227683 {source="ncithesaurus:Left_Ureter"} is_a: UBERON:0000056 ! ureter property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI [Term] id: UBERON:0001224 name: renal pelvis namespace: uberon def: "A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]." [MP:0004194] comment: In this ontology, the renal pelvis is represented as the area of part-overlap between the kidney and the ureter subset: pheno_slim subset: uberon_slim synonym: "kidney pelvis" EXACT [] synonym: "p. renallis" RELATED LATIN [http://en.wikipedia.org/wiki/Renal_pelvis] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] xref: CALOHA:TS-2230 xref: EMAPA:17948 xref: FMA:15575 xref: GAID:426 xref: galen:RenalPelvis xref: http://linkedlifedata.com/resource/umls/id/C0227666 xref: http://www.snomedbrowser.com/Codes/Details/362221007 xref: MA:0000374 xref: MESH:D007682 xref: NCIT:C12887 xref: Renal:pelvis xref: UMLS:C0227666 {source="ncithesaurus:Renal_Pelvis"} relationship: part_of UBERON:0002113 {source="MA"} ! kidney relationship: part_of UBERON:0036295 ! renal pelvis/ureter property_value: depicted:by Illu:kidney2.jpg xsd:anyURI [Term] id: UBERON:0001225 name: cortex of kidney namespace: uberon def: "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." [http://en.wikipedia.org/wiki/Renal_cortex] subset: pheno_slim subset: uberon_slim synonym: "cortex renalis" EXACT LATIN [FMA:15581, FMA:TA] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 xref: CALOHA:TS-0503 xref: EMAPA:17952 xref: FMA:15581 xref: GAID:424 xref: galen:CortexOfKidney xref: http://linkedlifedata.com/resource/umls/id/C0022655 xref: http://www.snomedbrowser.com/Codes/Details/362211004 xref: MA:0000372 xref: MESH:D007672 xref: NCIT:C12739 xref: Renal:cortex xref: UMLS:C0022655 {source="ncithesaurus:Renal_Cortex"} relationship: part_of UBERON:0008987 {source="FMA"} ! renal parenchyma property_value: depicted:by Illu:kidney.jpg xsd:anyURI property_value: UBPROP:0000010 "In the adult metanephros, it forms a continuous smooth outer zone with a number of projections that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs.[WP]" xsd:string [Term] id: UBERON:0001226 name: major calyx namespace: uberon def: "portion of the urinary collecting system within the kidney that drains several minor calyces" [http://anatomy.uams.edu/anatomyhtml/kidney.html] comment: major calyx collects urine from several renal papillae; all major calyces unite to form the renal pelvis subset: uberon_slim synonym: "calices renales majores" EXACT LATIN [http://en.wikipedia.org/wiki/Major_calyx] synonym: "calices renales majores" RELATED LATIN [http://en.wikipedia.org/wiki/Major_calyx] synonym: "major calix" EXACT [] xref: EMAPA:18677 xref: FMA:15613 xref: http://www.snomedbrowser.com/Codes/Details/1106008 xref: MA:0001644 xref: Major:calyx is_a: UBERON:0006517 ! kidney calyx is_a: UBERON:0014401 ! renal venous blood vessel property_value: depicted:by Kidney:PioM.png xsd:anyURI [Term] id: UBERON:0001227 name: minor calyx namespace: uberon def: "portion of the urinary collecting system within the kidney that drains one renal papilla" [http://anatomy.uams.edu/anatomyhtml/kidney.html] comment: one renal papilla projects into the lumen of one minor calyx; several minor calyces unite to form a major calyx subset: uberon_slim synonym: "calices renales minores" EXACT LATIN [http://en.wikipedia.org/wiki/Minor_calyx] synonym: "calices renales minores" RELATED LATIN [http://en.wikipedia.org/wiki/Minor_calyx] synonym: "minor calix" EXACT [] xref: EMAPA:18678 xref: FMA:15614 xref: http://www.snomedbrowser.com/Codes/Details/26293004 xref: MA:0001645 xref: Minor:calyx is_a: UBERON:0006517 ! kidney calyx is_a: UBERON:0014401 ! renal venous blood vessel property_value: depicted:by Kidney:PioM.png xsd:anyURI [Term] id: UBERON:0001228 name: renal papilla namespace: uberon def: "Tip of renal pyramid projecting into a minor calyx." [http://anatomy.uams.edu/anatomyhtml/kidney.html] subset: pheno_slim subset: uberon_slim synonym: "kidney papilla" EXACT [MP:0011303] xref: BTO:0003925 xref: EMAPA:35727 xref: FMA:15622 xref: galen:RenalPapilla xref: http://linkedlifedata.com/resource/umls/id/C0022666 xref: http://www.snomedbrowser.com/Codes/Details/362214007 xref: MA:0002730 xref: MESH:D007679 xref: NCIT:C33460 xref: Renal:papilla xref: UMLS:C0022666 {source="ncithesaurus:Renal_Papilla"} relationship: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001294 ! inner medulla of kidney property_value: depicted:by Kidney:PioM.png xsd:anyURI [Term] id: UBERON:0001229 name: renal corpuscle namespace: uberon def: "the structure containing the glomerular capsule and the glomerulus that serves as the initial blood-filtering component of a nephron" [ISBN:0-683-40008-8, MP:0002827] comment: Together, the Bowmans capsule and the glomerulus comprise the definitive renal corpuscle. http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "corpusculum renale" EXACT LATIN [] synonym: "corpusculum renis" RELATED LATIN [http://en.wikipedia.org/wiki/Renal_corpuscle] synonym: "cortical renal corpuscle" RELATED [MA:0000376] synonym: "kidney corpuscle" RELATED [http://en.wikipedia.org/wiki/Renal_corpuscle] synonym: "Malphigian corpuscle" EXACT MISSPELLING [MA:0000376] synonym: "Malpighian corpuscle" EXACT [ZFA:0005281] xref: BTO:0000333 xref: CALOHA:TS-1317 xref: EMAPA:28236 xref: EMAPA:35726 xref: EV:0100385 xref: FMA:15625 xref: http://linkedlifedata.com/resource/umls/id/C0227635 xref: http://www.snomedbrowser.com/Codes/Details/361329009 xref: MA:0000376 xref: NCIT:C33456 xref: Renal:corpuscle xref: TAO:0005281 xref: UMLS:C0227635 {source="ncithesaurus:Renal_Corpuscle"} xref: VHOG:0001262 xref: ZFA:0005281 relationship: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001285 {source="MA", source="ZFA"} ! nephron property_value: depicted:by Renal:corpuscle.svg xsd:anyURI property_value: UBPROP:0000001 "A mass of arterial capillaries enveloped in a capsule and attached to a tubule in the kidney[BTO]" xsd:string {date_retrieved="2012-11-28", external_class="BTO:0000333", ontology="BTO", source="BTO:curator"} property_value: UBPROP:0000001 "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated. Paired highly vascularized structures of the pronephros, responsible for blood filtration.[XAO]" xsd:string {date_retrieved="2012-11-28", external_class="XAO:0000146", ontology="XAO", source="XAO:curator"} property_value: UBPROP:0000001 "The part of the nephron that filters blood.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005281", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001230 name: glomerular capsule namespace: uberon def: "A cup-like sac at the expanded beginning of a tubular component of a nephron that contains the glomerulus" [http://en.wikipedia.org/wiki/Bowman%27s_capsule, MGI:pvb, MP:0002828] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "Bowman's capsule" RELATED [TAO:0005254] synonym: "Bowmans capsule" EXACT [KUPO:0001001] synonym: "capsula glomerularis" EXACT LATIN [] synonym: "capsula glomeruli" RELATED LATIN [] synonym: "Malphigian capsule" RELATED MISSPELLING [BTO:0002297] synonym: "Malpighian capsule" RELATED [UBERO:cjm] synonym: "Mueller capsule" RELATED [BTO:0002297] synonym: "Muellerian capsule" RELATED [BTO:0002297] synonym: "pronephric glomerular capsule" RELATED [TAO:0005310] synonym: "renal glomerular capsule" EXACT [TAO:0005254] xref: AAO:0010526 xref: Bowman%27s:capsule xref: BTO:0002297 xref: EMAPA:27973 xref: EMAPA:28257 xref: FMA:15626 xref: http://linkedlifedata.com/resource/umls/id/C0524448 xref: http://www.snomedbrowser.com/Codes/Details/361331000 xref: KUPO:0001001 xref: MA:0001660 xref: NCIT:C32225 xref: TAO:0005254 xref: TAO:0005310 xref: UMLS:C0524448 {source="ncithesaurus:Bowman_s_Capsule"} xref: ZFA:0005254 xref: ZFA:0005310 relationship: part_of UBERON:0001229 ! renal corpuscle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg xsd:anyURI property_value: UBPROP:0000001 "Anatomical structure found in the kidney consisting of an expanded end of a kidney tubule surrounding a glomerulus and is the major site of filtration.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010526", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000009 "Fluids from blood in the glomerulus are collected in the Bowman's capsule and further processed along the nephron to form urine. This process is known as ultrafiltration[WP]." xsd:string property_value: UBPROP:0000011 "One fold of the S-shaped body gives rise to Bowman's capsule[GUDMAP]" xsd:string [Term] id: UBERON:0001231 name: nephron tubule namespace: uberon alt_id: UBERON:0004210 def: "An epithelial tube that is part of the nephron, the functional part of the kidney." [GO:0072078, http://en.wikipedia.org/wiki/Renal_tubule] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "kidney tubule" EXACT [GAID:433] synonym: "renal tubule" BROAD [] synonym: "tubulus renalis" EXACT [] synonym: "uriniferous tubule" RELATED [MA:0000377] xref: BTO:0000343 xref: CALOHA:TS-1262 xref: EFO:0003666 xref: EMAPA:27782 xref: EV:0100387 xref: FMA:15627 xref: GAID:433 xref: http://linkedlifedata.com/resource/umls/id/C0022674 xref: http://www.snomedbrowser.com/Codes/Details/361332007 xref: MA:0000377 xref: MESH:D007684 xref: NCIT:C49274 xref: Renal:tubule xref: TAO:0001287 xref: UMLS:C0022674 {source="ncithesaurus:Renal_Tubule"} xref: ZFA:0001287 is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0009773 {source="GO"} ! renal tubule property_value: UBPROP:0000012 "note that in ISBN:0073040584 (Vertebrates, Kardong), the uriniferous tubule contains the nephron, so we have a separate class, rather than using a synonym, as in MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001232 name: collecting duct of renal tubule namespace: uberon def: "The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient" [GO:0072044, http://en.wikipedia.org/wiki/Collecting_tubule] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arcuate renal tubule" RELATED [http://en.wikipedia.org/wiki/Connecting_tubule] synonym: "collecting duct" EXACT [GO:0072044] synonym: "collecting duct system" RELATED [BTO:0000761] synonym: "collecting tubule" RELATED [] synonym: "junctional tube" RELATED [http://en.wikipedia.org/wiki/Connecting_tubule] synonym: "kidney collecting duct" EXACT [] synonym: "kidney collecting tubule" RELATED [] synonym: "renal collecting tubule" EXACT [FMA:15628] synonym: "tubulus renalis arcuatus" EXACT LATIN [http://en.wikipedia.org/wiki/Connecting_tubule] synonym: "tubulus renalis colligens" EXACT [] synonym: "ureteric tree" RELATED [EMAPA:28407] xref: BTO:0000761 xref: CALOHA:TS-0860 xref: Collecting:tubule xref: EMAPA:28407 xref: EV:0100391 xref: FMA:15628 xref: GAID:434 xref: http://www.snomedbrowser.com/Codes/Details/28202009 xref: MA:0000371 xref: MESH:D007685 xref: TAO:0005294 xref: ZFA:0005294 is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0001285 {notes="checkme", source="GO"} ! nephron property_value: UBPROP:0000001 "Renal duct that collects the output from renal tubules.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005294", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "in ISBN:0073040584 (Vertebrates, Kardong), the nephron is adjacent to the collecting tubule, consistent with FMA, but not GO. Wikipedia says: Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001252 name: adventitia of ureter namespace: uberon def: "An adventitia that is part of a ureter." [OBOL:automatic] synonym: "external adventitia of ureter" EXACT [] synonym: "tunica adventitia (ureter)" EXACT LATIN [FMA:15892, FMA:TA] synonym: "tunica adventitia ureteris" EXACT LATIN [FMA:15892, FMA:TA] synonym: "ureter adventitia" EXACT [] synonym: "ureteral adventitia" EXACT [] xref: EMAPA:28114 xref: FMA:15892 xref: http://www.snomedbrowser.com/Codes/Details/392273001 xref: http://www.snomedbrowser.com/Codes/Details/47879001 xref: MA:0002652 relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter [Term] id: UBERON:0001253 name: lamina propria of ureter namespace: uberon def: "A lamina propria that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "lamina propria mucosa of ureter" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of ureter" EXACT [OBOL:automatic] synonym: "ureter lamina propria" EXACT [] synonym: "ureter lamina propria mucosa" EXACT [OBOL:automatic] synonym: "ureter lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:28841 xref: FMA:15896 xref: http://www.snomedbrowser.com/Codes/Details/2771005 xref: MA:0002653 relationship: part_of UBERON:0004980 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mucosa of ureter [Term] id: UBERON:0001254 name: urothelium of ureter namespace: uberon def: "The luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder[MP]" [MP:0000535] subset: pheno_slim synonym: "transitional epithelium of ureter" EXACT [] synonym: "ureter luminal urothelium" RELATED INCONSISTENT [MP:0000535] synonym: "ureter transitional epithelium" EXACT [] synonym: "ureter urothelium" EXACT [] xref: EMAPA:28089 xref: FMA:15897 xref: MA:0002655 is_a: UBERON:0000365 ! urothelium relationship: part_of UBERON:0000056 ! ureter property_value: UBPROP:0000012 "MP treats ureter urothelium and ureter luminal urothelium as exact synonyms, yes MA treats these as distinct; see also: transitional epithelium vs urothelium" xsd:string {external_ontology="MP"} [Term] id: UBERON:0001255 name: urinary bladder namespace: uberon def: "distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." [http://en.wikipedia.org/wiki/Urinary_bladder, MGI:anna] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "bladder" BROAD [EHDAA2:0000174] synonym: "urocyst" RELATED [http://en.wikipedia.org/wiki/Urinary_bladder] synonym: "vesica" RELATED [BTO:0001418] synonym: "vesica urinaria" EXACT LATIN [http://en.wikipedia.org/wiki/Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 xref: EFO:0000290 xref: EHDAA2:0000174 xref: EHDAA:9328 xref: EMAPA:18321 xref: EV:0100098 xref: FMA:15900 xref: GAID:0000004 xref: galen:UrinaryBladder xref: http://linkedlifedata.com/resource/umls/id/C0005682 xref: http://www.snomedbrowser.com/Codes/Details/302512001 xref: MA:0000380 xref: MAT:0000122 xref: MESH:A05.810.161 xref: MIAA:0000122 xref: NCIT:C12414 xref: OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA xref: UMLS:C0005682 {source="ncithesaurus:Bladder"} xref: Urinary:bladder xref: VHOG:0000740 xref: XAO:0000154 relationship: part_of UBERON:0001556 {source="FMA"} ! lower urinary tract property_value: depicted:by Urinary:system.svg xsd:anyURI property_value: UBPROP:0000001 "A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000623", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.577-78"} property_value: UBPROP:0000007 "vesical" xsd:string property_value: UBPROP:0000008 "The urinary bladder evolved in tetrapods. Birds to not possess a true urinary bladder, although Palaeognathae have an undifferentiated cloacal outpocketing that serves a similar function[https://github.com/obophenotype/uberon/issues/454]" xsd:string [Term] id: UBERON:0001256 name: wall of urinary bladder namespace: uberon def: "An anatomical wall that lines the insider of a urinary bladder." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "anatomical wall of bladder" EXACT [OBOL:automatic] synonym: "anatomical wall of urinary bladder" EXACT [OBOL:automatic] synonym: "bladder anatomical wall" EXACT [OBOL:automatic] synonym: "bladder wall" EXACT [OBOL:automatic] synonym: "urinary bladder anatomical wall" EXACT [OBOL:automatic] synonym: "urinary bladder wall" EXACT [] synonym: "wall of bladder" EXACT [OBOL:automatic] xref: BTO:0001462 xref: EMAPA:35175 xref: FMA:15902 xref: http://linkedlifedata.com/resource/umls/id/C0458421 xref: http://www.snomedbrowser.com/Codes/Details/362225003 xref: MA:0002493 xref: NCIT:C48941 xref: UMLS:C0458421 {source="ncithesaurus:Bladder_Wall"} relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: UBERON:0001257 name: trigone of urinary bladder namespace: uberon def: "the smooth triangular region of the wall of the urinary bladder formed by the two ureteral orifices and the internal urethral orifice; it is an area in which the muscle fibers are closely adherent to the mucosa" [MGI:anna, MP:0011768] subset: pheno_slim subset: uberon_slim synonym: "bladder trigone" EXACT [] synonym: "deep trigone" EXACT [] synonym: "dorsal bladder neck" RELATED [EMAPA:35174] synonym: "Lieutaud's trigone" EXACT [] synonym: "musculus trigoni vesicae profundus" EXACT LATIN [FMA:15910, FMA:TA] synonym: "trigone of bladder" EXACT [] synonym: "trigonum vesicae" EXACT LATIN [FMA:15910, FMA:TA] synonym: "trigonum vesicae urinariae" RELATED LATIN [http://en.wikipedia.org/wiki/Trigone_of_urinary_bladder] synonym: "urinary bladder trigone" EXACT [] synonym: "vesical trigone" EXACT [] xref: EMAPA:35174 xref: FMA:15910 xref: galen:TrigoneOfUrinaryBladder xref: http://en.wikipedia.org/wiki/Trigone_of_urinary_bladder xref: http://linkedlifedata.com/resource/umls/id/C0447586 xref: http://www.snomedbrowser.com/Codes/Details/272663002 xref: MA:0002492 xref: NCIT:C12331 xref: UMLS:C0447586 {source="ncithesaurus:Bladder_Trigone"} relationship: part_of UBERON:0006082 ! fundus of urinary bladder property_value: depicted:by Illu:bladder.jpg xsd:anyURI property_value: UBPROP:0000009 "The area is very sensitive to expansion and once stretched to a certain degree, the urinary bladder signals the brain of its need to empty. The signals become stronger as the bladder continues to fill." xsd:string property_value: UBPROP:0000011 "Embryologically, the trigone of the bladder is derived from the caudal end of mesonephric ducts, which is of mesodermal origin (the rest of the bladder is endodermal). In the female the mesonephric ducts regresses, causing the trigone to be less prominent, but still present" xsd:string {source="WP"} [Term] id: UBERON:0001258 name: neck of urinary bladder namespace: uberon def: "The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]." [http://en.wikipedia.org/wiki/Neck_of_urinary_bladder, MP:anna] subset: pheno_slim subset: uberon_slim synonym: "bladder neck" EXACT [] synonym: "cervix vesicae" EXACT LATIN [FMA:15912, FMA:TA] synonym: "cervix vesicae urinariae" RELATED LATIN [http://en.wikipedia.org/wiki/Neck_of_urinary_bladder] synonym: "collum vesicae" EXACT LATIN [FMA:15912, FMA:TA] synonym: "neck of bladder" EXACT [] synonym: "urinary bladder neck" EXACT [] synonym: "vesical neck" EXACT [] xref: EMAPA:36078 xref: FMA:15912 xref: galen:UrinaryBladderNeck xref: http://en.wikipedia.org/wiki/Neck_of_urinary_bladder xref: http://linkedlifedata.com/resource/umls/id/C0227716 xref: http://www.snomedbrowser.com/Codes/Details/362227006 xref: MA:0002491 xref: NCIT:C12336 xref: UMLS:C0227716 {source="ncithesaurus:Bladder_Neck"} relationship: part_of UBERON:0001255 ! urinary bladder property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/6/63/Gray1156.png xsd:anyURI [Term] id: UBERON:0001259 name: mucosa of urinary bladder namespace: uberon def: "the mucous membrane lining the urinary bladder" [MGI:anna, MP:0011766] subset: efo_slim subset: pheno_slim synonym: "bladder mucosa" EXACT [] synonym: "bladder mucous membrane" EXACT [OBOL:automatic] synonym: "bladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder" EXACT [] synonym: "mucous membrane of urinary bladder" EXACT [] synonym: "tunica mucosa (vesica urinaria)" EXACT LATIN [FMA:15928, FMA:TA] synonym: "tunica mucosa vesicae" EXACT LATIN [FMA:15928, FMA:TA] synonym: "tunica mucosa vesicae urinariae" EXACT [MP:MP] synonym: "urinary bladder mucosa" EXACT [] synonym: "urinary bladder mucous membrane" EXACT [OBOL:automatic] xref: EFO:0000293 xref: EMAPA:35897 xref: FMA:15928 xref: galen:MucousMembraneOfUrinaryBladder xref: http://linkedlifedata.com/resource/umls/id/C0227691 xref: http://www.snomedbrowser.com/Codes/Details/362224004 xref: MA:0001692 xref: NCIT:C32205 xref: UMLS:C0227691 {source="ncithesaurus:Bladder_Mucosa"} relationship: part_of UBERON:0001256 ! wall of urinary bladder [Term] id: UBERON:0001260 name: serosa of urinary bladder namespace: uberon def: "A serous membrane that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder serosa" EXACT [] synonym: "bladder serous membrane" EXACT [OBOL:automatic] synonym: "serosa of bladder" EXACT [] synonym: "serous coat of bladder" EXACT [] synonym: "serous coat of urinary bladder" EXACT [] synonym: "serous membrane of bladder" EXACT [OBOL:automatic] synonym: "serous membrane of urinary bladder" EXACT [OBOL:automatic] synonym: "tunica serosa (vesica urinaria)" EXACT LATIN [FMA:15932, FMA:TA] synonym: "tunica serosa vesicae" EXACT LATIN [FMA:15932, FMA:TA] synonym: "urinary bladder serosa" EXACT [] synonym: "urinary bladder serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of urinary bladder" EXACT [] xref: EMAPA:28661 xref: FMA:15932 xref: http://www.snomedbrowser.com/Codes/Details/5868002 xref: MA:0001696 relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder property_value: IAO:0000116 "TODO - check serosa/peritoneum" xsd:string [Term] id: UBERON:0001261 name: lamina propria of urinary bladder namespace: uberon def: "A lamina propria that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder lamina propria" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria of bladder" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria" EXACT [] synonym: "urinary bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:30088 xref: FMA:15935 xref: http://linkedlifedata.com/resource/umls/id/C1706967 xref: MA:0001695 xref: NCIT:C48940 xref: UMLS:C1706967 {source="ncithesaurus:Bladder_Lamina_Propria"} relationship: part_of UBERON:0001259 ! mucosa of urinary bladder property_value: UBPROP:0000010 "Contains loose to dense connective tissue, variably sized blood vessels that may be close to epithelium, lymphatics, variable adipose tissue" xsd:string [Term] id: UBERON:0001284 name: renal column namespace: uberon def: "A column of tissue that is histologically identical to tissue found in the renal cortex, but which is located in the medulla between the renal pyramids." [http://anatomy.uams.edu/anatomyhtml/kidney.html] subset: uberon_slim synonym: "Bertin's column" RELATED [FMA:17633] synonym: "column of Bertin" RELATED [FMA:17633] synonym: "column of Bertini" EXACT [] synonym: "columna Bertini" EXACT LATIN [FMA:17633, FMA:TA] synonym: "columnae renales" RELATED LATIN [http://en.wikipedia.org/wiki/Renal_column] synonym: "cortical column" BROAD [ncithesaurus:Cortical_Column] synonym: "kidney column" EXACT [MA:0001651] synonym: "renal column of Bertini" EXACT [] synonym: "renal cortical column" EXACT [] xref: EMAPA:37487 {source="MA:th"} xref: FMA:17633 xref: http://linkedlifedata.com/resource/umls/id/C0736346 xref: MA:0001651 xref: NCIT:C32387 xref: Renal:column relationship: part_of UBERON:0002189 {source="FMA", source="MA"} ! outer cortex of kidney property_value: depicted:by Illu:kidney2.jpg xsd:anyURI property_value: IAO:0000116 "Check part_of location against textual definition" xsd:string [Term] id: UBERON:0001285 name: nephron namespace: uberon def: "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]" [http://en.wikipedia.org/wiki/Nephron, http://www.ncbi.nlm.nih.gov/pubmed/9268568] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] synonym: "nephroneum" RELATED LATIN [http://en.wikipedia.org/wiki/Nephron] synonym: "tubulus renalis" RELATED LATIN [http://en.wikipedia.org/wiki/Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 xref: EMAPA:35592 xref: EV:0100384 xref: FMA:17640 xref: GAID:428 xref: http://en.wikipedia.org/wiki/Nephron xref: http://linkedlifedata.com/resource/umls/id/C0027713 xref: http://www.snomedbrowser.com/Codes/Details/361337001 xref: MA:0000375 xref: MESH:D009399 xref: NCIT:C13048 xref: TAO:0002153 xref: UMLS:C0027713 {source="ncithesaurus:Nephron"} xref: ZFA:0005282 relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI property_value: IAO:0000116 "kidney terms require review for cross-vertebrate compatibility and developmental relationships." xsd:string property_value: UBPROP:0000001 "Functional unit of the kidney that filters waste.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002153", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)" xsd:string {source="GO"} [Term] id: UBERON:0001286 name: Bowman's space namespace: uberon def: "A narrow chalice-shaped cavity between the glomerular and capsular epithelium of the glomerular capsule of the kidney[TFD]. Between the visceral and parietal layers, into which the filtrate enters after passing through the podocytes' filtration slits[WP]. luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries[MP]" [http://en.wikipedia.org/wiki/Bowman's_space, http://medical-dictionary.thefreedictionary.com/bowman's+space, MP:0011499] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Bowman's space" EXACT [] synonym: "Bowmanb%s space" RELATED [TAO:0005312] synonym: "capsular space" EXACT [http://medical-dictionary.thefreedictionary.com/bowman's+space] synonym: "glomerular capsule space" EXACT [MP:0011499] synonym: "glomerular urinary space" EXACT [MP:0011499] synonym: "inter-glomerular space" EXACT [ZFA:0005283] synonym: "inter-glomerular space" EXACT [ZFA:0005312] synonym: "pronephric capsular space" EXACT [ZFA:0005312] synonym: "renal capsular space" EXACT [ZFA:0005283] synonym: "urinary space" EXACT [] synonym: "urinary space of renal corpuscle" EXACT [EMAPA:28263] xref: Bowman's:space xref: EMAPA:27985 xref: EMAPA:28263 xref: FMA:17676 xref: http://linkedlifedata.com/resource/umls/id/C0227643 xref: http://www.snomedbrowser.com/Codes/Details/244284006 xref: MA:0001664 xref: NCIT:C33840 xref: TAO:0005283 xref: TAO:0005312 xref: UMLS:C0227643 {source="ncithesaurus:Urinary_Space"} xref: ZFA:0005283 xref: ZFA:0005312 relationship: part_of UBERON:0001230 ! glomerular capsule property_value: IAO:0000116 "TODO - fix ZFA" xsd:string property_value: UBPROP:0000001 "Space between the renal glomerulus and the glomerular capsule. Renal filtrate collects here then passes into the renal tubule.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005283", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Space between the renal glomerulus and the glomerular capsule. Renal filtrate collects here then passes into the renal tubule.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005312", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001287 name: proximal convoluted tubule namespace: uberon def: "The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule." [GO:0072019] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "1st convoluted tubule" RELATED [] synonym: "first convoluted tubule" RELATED [] synonym: "kidney proximal convoluted tubule" RELATED [EMAPA:28287] synonym: "PCT" RELATED [] synonym: "proximal convoluted renal tubule" EXACT [] synonym: "renal proximal convoluted tubule" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "tubulus contortus proximalis" EXACT [] synonym: "tubulus contortus proximalis" RELATED LATIN [http://en.wikipedia.org/wiki/Proximal_convoluted_tubule] synonym: "tubulus convolutus proximalis" RELATED LATIN [] xref: CALOHA:TS-2198 xref: EMAPA:28287 xref: EV:0100388 xref: FMA:17693 xref: http://en.wikipedia.org/wiki/Proximal_convoluted_tubule xref: http://linkedlifedata.com/resource/umls/id/C1514580 xref: http://www.snomedbrowser.com/Codes/Details/362220008 xref: MA:0001669 xref: NCIT:C33417 xref: TAO:0005290 xref: UMLS:C1514580 {source="ncithesaurus:Proximal_Convoluted_Tube"} xref: ZFA:0005290 is_a: UBERON:0006534 {source="MA"} ! renal convoluted tubule is_a: UBERON:0006853 ! renal cortex tubule relationship: part_of UBERON:0004134 {notes="MA uses subclass", source="GOC:mtg_kidney_jan10"} ! proximal tubule property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI property_value: UBPROP:0000001 "Renal tubule that connects to the renal corpuscle.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005290", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001288 name: loop of Henle namespace: uberon def: "the section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine" [MGI:csmith, MP:0004755] subset: pheno_slim subset: uberon_slim synonym: "ansa nephroni" EXACT LATIN [http://en.wikipedia.org/wiki/Loop_of_Henle] synonym: "Henle loop" EXACT [] synonym: "Henle's loop" EXACT [] xref: BTO:0004608 xref: EMAPA:19280 xref: EV:0100390 xref: FMA:17698 xref: GAID:437 xref: http://en.wikipedia.org/wiki/Loop_of_Henle xref: http://linkedlifedata.com/resource/umls/id/C0023986 xref: http://www.snomedbrowser.com/Codes/Details/361335009 xref: MA:0001675 xref: MESH:D008138 xref: NCIT:C33006 xref: UMLS:C0023986 {source="ncithesaurus:Loop_of_Henle"} xref: VHOG:0001270 is_a: UBERON:0007685 ! region of nephron tubule property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI property_value: IAO:0000116 "the definitions of some kidney parts (e.g. proximal straight tubule) refer to Henle's loop, even in species where this may not be present. Requires review." xsd:string property_value: RO:0002174 NCBITaxon:8353 property_value: RO:0002175 NCBITaxon:8782 property_value: UBPROP:0000001 "A highly specialized segment of the mammalian kidney tubules, that dips into the medulla. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.648, see_Liem_KF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001270", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "The structure differs considerably between species; there is a definite physical loop of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus. However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of the mammalian loop of Henle were found to be present in the pronephros of the frog larva ." xsd:string {source="https://doi.org/10.1371/journal.pone.0099864"} property_value: UBPROP:0000009 "The loop of Henle plays an important role in creating a concentration gradient in the medulla of the kidney. It is involved in reabsorption of filtered water and ions including sodium, potassium and calcium, and independently regulates both the volume and osmolarity of body fluids." xsd:string {source="https://doi.org/10.1371/journal.pone.0099864"} [Term] id: UBERON:0001289 name: descending limb of loop of Henle namespace: uberon def: "the portion of the renal tubule that constitutes the proximal part of the loop of Henle, has low permeability to ions and urea, and is highly permeable to water; it consists of an initial short thick segment lined by low simple cuboidal epithelium and a long thin segment lined by simple squamous epithelium; however, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure" [MGI:anna, MP:0011341] subset: pheno_slim subset: uberon_slim synonym: "descending limb" BROAD [] synonym: "descending limb of Henle's loop" EXACT [] synonym: "loop of Henle descending limb" EXACT [] xref: EMAPA:35511 xref: FMA:17705 xref: http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_henle xref: http://linkedlifedata.com/resource/umls/id/C0227657 xref: http://www.snomedbrowser.com/Codes/Details/245350001 xref: MA:0001679 xref: NCIT:C32456 xref: UMLS:C0227657 {source="ncithesaurus:Descending_Limb_of_the_Henle_s_Loop"} is_a: UBERON:0007685 {source="FMA"} ! region of nephron tubule relationship: part_of UBERON:0001288 {source="FMA"} ! loop of Henle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0001290 name: proximal straight tubule namespace: uberon alt_id: UBERON:0005166 def: "The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule." [GO:0072020] subset: uberon_slim subset: vertebrate_core synonym: "pars recta" RELATED [] synonym: "pars recta tubuli renalis" RELATED [BTO:0000055] synonym: "proximal tubule segment 3" RELATED [MA:0002614] synonym: "S3" EXACT [GO:0072020] synonym: "segment 3 of proximal tubule" RELATED [EMAPA:29661] synonym: "thick descending limb of proximal tubule" EXACT [] synonym: "tubulus rectus proximalis" EXACT [] xref: BTO:0000055 xref: EMAPA:29661 xref: EMAPA:29669 xref: FMA:17716 xref: http://en.wikipedia.org/wiki/Proximal_straight_tubule xref: MA:0002614 xref: TAO:0005291 xref: ZFA:0005291 is_a: UBERON:0006853 ! renal cortex tubule is_a: UBERON:0009035 {source="MA"} ! renal straight tubule relationship: part_of UBERON:0001289 {source="MA"} ! descending limb of loop of Henle relationship: part_of UBERON:0004134 {notes="MA uses subclass", source="GOC:mtg_kidney_jan10"} ! proximal tubule relationship: part_of UBERON:0006542 {source="MA"} ! outer medulla outer stripe loop of Henle property_value: IAO:0000116 "TODO - is S3 exactly coincident with PST? todo - ensure relationships work across species (loop of Henle)" xsd:string property_value: UBPROP:0000001 "Portion of the renal tubule which is just posterior to the proximal convoluted tubule.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005291", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001291 name: thick ascending limb of loop of Henle namespace: uberon def: "the distal sub-portion of the ascending loop of Henle which is lined by simple cuboidal epithelium and enters the renal cortex to empty a hypotonic filtrate into the distal convoluted tubule" [MGI:anna, MP:0011344] subset: pheno_slim subset: uberon_slim synonym: "ascending thick limb" EXACT [] synonym: "distal straight tubule" EXACT [MA:0001677] synonym: "loop of Henle ascending limb thick segment" EXACT [MA:0001677] synonym: "straight portion of distal convoluted renal tubule" EXACT [] synonym: "straight portion of distal convoluted tubule" EXACT [FMA:17722] synonym: "thick ascending limb" EXACT [] synonym: "thick ascending limb of distal tubule" EXACT [FMA:17722] synonym: "thick ascending limb of Henle's loop" EXACT [] synonym: "tubulus rectus distalis" EXACT [FMA:17722] synonym: "tubulus rectus distalis" RELATED LATIN [http://en.wikipedia.org/wiki/Thick_ascending_limb_of_loop_of_Henle] xref: EMAPA:28396 xref: EMAPA:29671 xref: EMAPA:35512 xref: FMA:17722 xref: http://en.wikipedia.org/wiki/Thick_ascending_limb_of_loop_of_Henle xref: http://www.snomedbrowser.com/Codes/Details/244953001 xref: MA:0001677 is_a: UBERON:0009035 {source="MA"} ! renal straight tubule relationship: part_of UBERON:0005164 ! ascending limb of loop of Henle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI property_value: IAO:0000116 "TODO - thick/thin check. Also - does the loop of Henle overlap the distal convoluted tubule? FMA divides DCT into straight and convoluted portions" xsd:string [Term] id: UBERON:0001292 name: distal convoluted tubule namespace: uberon def: "The first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa." [GO:0072025] subset: pheno_slim subset: uberon_slim synonym: "distal convoluted renal tubule" EXACT [] synonym: "second convoluted tubule" RELATED [] synonym: "tubulus contortus distalis" EXACT [] synonym: "tubulus contortus distalis" RELATED LATIN [http://en.wikipedia.org/wiki/Distal_convoluted_tubule] synonym: "tubulus convolutus distalis" RELATED LATIN [] xref: EMAPA:28393 xref: EV:0100389 xref: FMA:17721 xref: http://en.wikipedia.org/wiki/Distal_convoluted_tubule xref: http://linkedlifedata.com/resource/umls/id/C0022676 xref: http://www.snomedbrowser.com/Codes/Details/361336005 xref: MA:0001666 xref: NCIT:C32469 xref: UMLS:C0022676 {source="ncithesaurus:Distal_Convoluted_Tubule"} is_a: UBERON:0006534 {source="MA"} ! renal convoluted tubule is_a: UBERON:0006853 ! renal cortex tubule relationship: part_of UBERON:0004135 {source="EMAPA", source="GO", source="MA-modified-from-isa"} ! distal tubule property_value: depicted:by Kidney:nephron.png xsd:anyURI property_value: UBPROP:0000001 "a portion of kidney nephron between the loop of Henle and the collecting duct system[Wikipedia:Distal_convoluted_tubule]." xsd:string {source="http://en.wikipedia.org/wiki/Distal_convoluted_tubule"} property_value: UBPROP:0000009 "in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter." xsd:string [Term] id: UBERON:0001293 name: outer medulla of kidney namespace: uberon def: "The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla[GO]." [GOC:mtg_kidney_jan10, https://doi.org/10.1371/journal.pone.0099864] subset: pheno_slim synonym: "kidney outer medulla" RELATED [BTO:0001746] synonym: "outer renal medulla" EXACT [] synonym: "outer zone of medulla of kidney" EXACT [] synonym: "outer zone of renal medulla" EXACT [] synonym: "renal outer medulla" EXACT [BTO:0001746] synonym: "set of outer region of renal pyramids" RELATED [FMA:17733] synonym: "zona externa (medullaris renalis)" EXACT LATIN [FMA:17733, FMA:TA] synonym: "zona externa medullae renalis" EXACT LATIN [FMA:17733, FMA:TA] xref: BTO:0001746 xref: CALOHA:TS-0508 xref: EMAPA:28310 xref: FMA:17733 xref: MA:0001653 relationship: part_of UBERON:0000362 ! renal medulla [Term] id: UBERON:0001294 name: inner medulla of kidney namespace: uberon def: "Innermost region of the mammalian kidney." [GO:0072053] subset: pheno_slim synonym: "inner renal medulla" EXACT [] synonym: "inner zone of medulla of kidney" EXACT [] synonym: "inner zone of renal medulla" EXACT [] synonym: "kidney inner medulla" RELATED [BTO:0001745] synonym: "renal inner medulla" EXACT [BTO:0001745] synonym: "set of inner region of renal pyramids" EXACT [] synonym: "zona interna (medullaris renalis)" EXACT LATIN [FMA:17734, FMA:TA] synonym: "zona interna medullae renalis" EXACT LATIN [FMA:17734, FMA:TA] xref: BTO:0001745 xref: CALOHA:TS-0506 xref: EMAPA:28349 xref: FMA:17734 xref: MA:0001652 relationship: part_of UBERON:0000362 ! renal medulla property_value: UBPROP:0000008 "unique to mammals" xsd:string {source="GO:0072053"} [Term] id: UBERON:0001333 name: male urethra namespace: uberon def: "A urethra that is part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim xref: BTO:0004089 xref: EMAPA:18692 xref: FMA:19668 xref: http://linkedlifedata.com/resource/umls/id/C0458452 xref: http://www.snomedbrowser.com/Codes/Details/264085007 xref: MA:0002640 xref: Male:urethra xref: NCIT:C33050 xref: UMLS:C0458452 {source="ncithesaurus:Male_Urethra"} is_a: UBERON:0000057 ! urethra property_value: depicted:by Female:anatomy.png xsd:anyURI [Term] id: UBERON:0001334 name: female urethra namespace: uberon def: "A urethra that is part of a female reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "urethra feminina" RELATED [BTO:0004088] synonym: "urethra muliebris" RELATED [BTO:0004088] xref: BTO:0004088 xref: EMAPA:28747 xref: Female:urethra xref: FMA:19669 xref: http://linkedlifedata.com/resource/umls/id/C0458485 xref: http://www.snomedbrowser.com/Codes/Details/264469008 xref: MA:0002637 xref: NCIT:C32591 xref: UMLS:C0458485 {source="ncithesaurus:Female_Urethra"} is_a: UBERON:0000057 ! urethra property_value: depicted:by Female:anatomy.png xsd:anyURI [Term] id: UBERON:0001335 name: prostatic urethra namespace: uberon def: "the widest and most dilatable part of the male urethra canal which runs almost vertically through the prostate from its base to its apex, lying nearer its anterior than its posterior surface; this portion of the urethral canal is spindle-shaped, being wider in the middle than at either extremity, and narrowest below, where it joins the membranous portion; it is lined by transitional epithelium and contains in its posterior wall, or floor, the orifices of the prostatic utricle, ejaculatory ducts, and prostatic ducts, collectively known as the seminal colliculus (aka verumontanum)" [MGI:anna, MP:0011777] subset: pheno_slim subset: uberon_slim synonym: "male prostatic urethra" EXACT [MP:0011777] synonym: "pars prostatica urethrae" EXACT LATIN [http://en.wikipedia.org/wiki/Prostatic_urethra] synonym: "pars prostatica urethrae" EXACT [MP:0011777] synonym: "pars prostatica urethrae" RELATED [BTO:0003163] synonym: "prostatic part of male urethra" EXACT [MP:0011777] synonym: "prostatic part of urethra" EXACT [] xref: BTO:0003163 xref: EMAPA:30942 xref: FMA:19673 xref: http://linkedlifedata.com/resource/umls/id/C0458450 xref: http://www.snomedbrowser.com/Codes/Details/279434009 xref: MA:0002646 xref: NCIT:C13101 xref: Prostatic:urethra xref: UMLS:C0458450 {source="ncithesaurus:Prostatic_Portion_of_the_Male_Urethra"} relationship: part_of UBERON:0001333 {source="FMA", source="MA"} ! male urethra property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray1142.png xsd:anyURI [Term] id: UBERON:0001336 name: membranous urethra of male or female namespace: uberon subset: uberon_slim synonym: "intermediate part of urethra" EXACT [] synonym: "intermediate urethra" EXACT [] synonym: "membranous part of urethra" EXACT [] synonym: "membranous urethra" EXACT INCONSISTENT [MA:0002647] synonym: "pars intermedia urethrae" EXACT LATIN [FMA:19674, FMA:TA] synonym: "pars membranacea (urethrae)" EXACT [] xref: EMAPA:37542 {source="MA:th"} xref: MA:0002647 relationship: part_of UBERON:0000057 ! urethra property_value: UBPROP:0000012 "MA class sex-neutral" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001337 name: spongiose part of urethra namespace: uberon def: "the longest part of the male urethra contained in the corpus spongiosum and extending from the end of the membranous portion to the external urethral orifice; commencing below the inferior fascia of the urogenital diaphragm it passes forward and upward to the front of the symphysis pubis; and then, in the flaccid condition of the penis, it bends downward and forward; while narrow and of uniform size in the body of the penis, it is dilated behind, within the bulb, and again anteriorly within the glans penis, where it forms the fossa navicularis urethrae; the spongy urethra is lined by pseudostratified columnar epithelium proximally, and by stratified squamous epithelium distally" [MGI:anna, MP:0011779] subset: pheno_slim subset: uberon_slim synonym: "cavernous portion of male urethra" EXACT [MP:0011779] synonym: "male spongiose urethra" EXACT [MP:0011779] synonym: "male spongy urethra" EXACT [] synonym: "pars cavernosa urethrae" EXACT [MP:0011779] synonym: "pars spongiosa" EXACT LATIN [FMA:19675, FMA:TA] synonym: "pars spongiosa (urethra masculina)" EXACT LATIN [FMA:19675, FMA:TA] synonym: "pars spongiosa urethrae masculinae" EXACT [MP:0011779] synonym: "penile urethra" EXACT [MP:0011779] synonym: "spongiose urethra" EXACT [MP:0011779] synonym: "spongy urethra (male)" EXACT [] xref: EMAPA:30944 xref: FMA:19675 xref: http://www.snomedbrowser.com/Codes/Details/263341006 xref: MA:0002644 xref: Penile:urethra relationship: part_of UBERON:0001333 {source="FMA"} ! male urethra property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray1142.png xsd:anyURI [Term] id: UBERON:0001338 name: urethral gland namespace: uberon def: "Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine" [MP:anna] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "gland of urethra" EXACT [OBOL:automatic] synonym: "urethra gland" EXACT [] synonym: "urethra gland (male or female)" EXACT [] synonym: "urethral mucuous gland" EXACT [] xref: EMAPA:37784 {source="MA:th"} xref: FMA:19683 xref: http://www.snomedbrowser.com/Codes/Details/279477005 xref: MA:0001688 relationship: part_of UBERON:0000057 ! urethra property_value: UBPROP:0000012 "NCIT:C12339 paraurethral gland belongs here" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0001552 name: kidney arcuate artery namespace: uberon def: "One of the curved arteries at the corticomedullary border of the kidney that arise from the interlobar arteries and give rise to the interlobular arteries." [http://en.wikipedia.org/wiki/Arcuate_artery_of_the_foot, MP:0011315] subset: pheno_slim subset: uberon_slim synonym: "arcuate artery" BROAD [MA:0002583] synonym: "renal arcuate artery" EXACT [] xref: EMAPA:28215 xref: FMA:70497 xref: http://en.wikipedia.org/wiki/Arcuate_arteries_of_the_kidney xref: MA:0002583 is_a: UBERON:0003644 ! kidney arterial blood vessel relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray553.png xsd:anyURI [Term] id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] subset: pheno_slim subset: uberon_slim xref: FMA:45659 xref: galen:LowerUrinaryTract xref: http://www.snomedbrowser.com/Codes/Details/181420004 xref: MA:0002636 is_a: BFO:0000040 ! material entity relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0002015 name: kidney capsule namespace: uberon def: "the tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage" [MGI:anna, MP:0011383] subset: pheno_slim subset: uberon_slim synonym: "capsula fibrosa renis" EXACT LATIN [FMA:66610, FMA:TA] synonym: "capsule of kidney" EXACT [] synonym: "fibrous capsule of kidney" EXACT [FMA:66610] synonym: "renal capsule" EXACT [GO:0072127] xref: EMAPA:18679 xref: FMA:66610 xref: galen:CapsuleOfKidney xref: http://linkedlifedata.com/resource/umls/id/C0227637 xref: http://www.snomedbrowser.com/Codes/Details/243657006 xref: Kidney:capsule xref: MA:0000370 xref: NCIT:C12885 xref: UMLS:C0227637 {source="ncithesaurus:Renal_Capsule"} relationship: part_of UBERON:0002113 ! kidney property_value: depicted:by Illu:kidney.jpg xsd:anyURI property_value: UBPROP:0000009 "provides some protection from trauma and damage." xsd:string property_value: UBPROP:0000010 "The renal capsule relates to the other layers in the following order (moving from innermost to outermost): renal medulla renal cortex renal capsule perinephric fat (or 'perirenal fat') renal fascia paranephric fat (or 'pararenal fat') peritoneum (anteriorly), and transversalis fascia (posteriorly).[Wikipedia:Kidney_capsule]" xsd:string [Term] id: UBERON:0002068 name: urachus namespace: uberon def: "A fibrous remnant of the allantoic stalk, a narrow fetal canal connecting the apex of the urinary bladder with the umbilicus located in the space of Retzius, between the transversalis fascia anteriorly and the peritoneum posteriorly. its lumen is normally obliterated during development, transforming the urachus into a solid cord, a functionless remnant that persists throughout life as the median umbilical ligament; failure of complete lumen obliteration may result in distinct congenital urachal remnant anomalies[MP]." [MP:0011852, MP:anna] subset: pheno_slim subset: uberon_slim xref: EHDAA2:0002137 xref: EHDAA:7016 xref: EHDAA:9332 xref: EMAPA:18323 xref: FMA:70343 xref: GAID:1313 xref: http://en.wikipedia.org/wiki/Urachus xref: http://linkedlifedata.com/resource/umls/id/C0041916 xref: http://www.snomedbrowser.com/Codes/Details/276858000 xref: MA:0001701 xref: MESH:A16.254.835 xref: NCIT:C12338 xref: RETIRED_EHDAA2:0002138 xref: UMLS:C0041916 {source="ncithesaurus:Urachus"} xref: VHOG:0000735 relationship: part_of UBERON:0001255 {source="EHDAA2"} ! urinary bladder property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/6/63/Gray1156.png xsd:anyURI property_value: UBPROP:0000001 "A fetal canal connecting the bladder with the allantois, persisting throughout life as a cord (median umbilical ligament). [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000735", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urachus"} property_value: UBPROP:0000007 "urachal" xsd:string [Term] id: UBERON:0002113 name: kidney namespace: uberon def: "A paired organ of the urinary tract which has the production of urine as its primary function." [http://anatomy.uams.edu/anatomyhtml/kidney.html, http://en.wikipedia.org/wiki/Kidney] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "reniculate kidney" NARROW SENSU [http://en.wikipedia.org/wiki/Reniculate_kidney] xref: AAO:0000250 xref: BTO:0000671 xref: CALOHA:TS-0510 xref: EFO:0000929 xref: EMAPA:17373 xref: EV:0100096 xref: FMA:7203 xref: GAID:423 xref: galen:Kidney xref: http://en.wikipedia.org/wiki/Kidney xref: http://linkedlifedata.com/resource/umls/id/C0022646 xref: http://www.snomedbrowser.com/Codes/Details/181414000 xref: MA:0000368 xref: MAT:0000119 xref: MESH:D007668 xref: MIAA:0000119 xref: NCIT:C12415 xref: OpenCyc:Mx4rvVjlYpwpEbGdrcN5Y29ycA xref: UMLS:C0022646 {source="ncithesaurus:Kidney"} xref: XAO:0003267 relationship: part_of UBERON:0011143 {source="FMA"} ! upper urinary tract property_value: UBPROP:0000001 "One of either of a pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000250", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000007 "renal" xsd:string property_value: UBPROP:0000202 FMA:264815 [Term] id: UBERON:0002120 name: pronephros namespace: uberon alt_id: UBERON:0005794 def: "In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, http://en.wikipedia.org/wiki/Pronephros] comment: Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 subset: efo_slim subset: organ_slim subset: uberon_slim synonym: "archinephron" RELATED [BTO:0001541] synonym: "embryonic kidney" RELATED [BTO:0001541] synonym: "pronephric kidney" EXACT [XAO:0002000] synonym: "pronephron" RELATED [BTO:0001541] xref: AAO:0011089 xref: BTO:0001541 xref: EFO:0000927 xref: EHDAA2:0001570 xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: http://en.wikipedia.org/wiki/Pronephros xref: http://linkedlifedata.com/resource/umls/id/C0231048 xref: http://www.snomedbrowser.com/Codes/Details/308804007 xref: MAT:0000117 xref: MIAA:0000117 xref: NCIT:C34280 xref: TAO:0000151 xref: UMLS:C0231048 {source="ncithesaurus:Pronephros"} xref: VHOG:0000037 xref: XAO:0002000 xref: ZFA:0000151 is_a: UBERON:0002113 {source="GO"} ! kidney property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011089", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000001 "The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000151", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637"} property_value: UBPROP:0000007 "pronephric" xsd:string [Term] id: UBERON:0002189 name: outer cortex of kidney namespace: uberon synonym: "kidney outer cortex" EXACT [MA:0001649] synonym: "outer renal cortex" EXACT [] xref: EMAPA:37485 {source="MA:th"} xref: FMA:74285 xref: MA:0001649 is_a: UBERON:0001225 ! cortex of kidney [Term] id: UBERON:0002303 name: juxtaglomerular apparatus namespace: uberon def: "An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]." [GO:0072206, http://en.wikipedia.org/wiki/Juxtaglomerular_apparatus] subset: pheno_slim subset: uberon_slim synonym: "complexus juxtaglomerularis" EXACT LATIN [] synonym: "juxtaglomerular complex" EXACT [MP:0002829] xref: BTO:0005157 xref: EMAPA:30449 xref: FMA:83599 xref: GAID:432 xref: http://linkedlifedata.com/resource/umls/id/C0022445 xref: http://www.snomedbrowser.com/Codes/Details/362219002 xref: Juxtaglomerular:apparatus xref: MA:0002546 xref: MESH:D007606 xref: NCIT:C32891 xref: UMLS:C0022445 {source="ncithesaurus:Juxtaglomerular_Apparatus"} is_a: BFO:0000040 ! material entity relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0002319 name: mesangium namespace: uberon def: "The inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries." [http://en.wikipedia.org/wiki/Mesangium, https://sourceforge.net/p/obo/foundational-model-of-anatomy-fma-requests/13/] subset: pheno_slim subset: uberon_slim xref: BTO:0002494 xref: EMAPA:28248 xref: EMAPA:36561 {source="MA:th"} xref: FMA:84139 xref: http://en.wikipedia.org/wiki/Mesangium xref: http://linkedlifedata.com/resource/umls/id/C0017655 xref: MA:0002617 xref: NCIT:C33101 xref: UMLS:C0017655 {source="ncithesaurus:Mesangium"} relationship: part_of UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0005215 ! kidney interstitium property_value: UBPROP:0000007 "mesangial" xsd:string property_value: UBPROP:0000012 "WP considers this the same as glomerular mesangium. In MA, glomerular and extraglomerular are distingsuished. FMA class has no definition and is a type of stroma, which is inconsistent with our classification of this here." xsd:string {external_ontology="MA"} [Term] id: UBERON:0002320 name: glomerular mesangium namespace: uberon def: "A thin membrane which helps to support the capillary loops in a renal glomerulus. It is connective tissue composed of mesangial cells - myofibroblasts phenotypically related to vascular smooth muscle cells (muscle, smooth, vascular), phagocytes and the mesangial extracellular matrix." [http://en.wikipedia.org/wiki/Glomerular_mesangium, MESH:A05.810.453.736.520.380] subset: pheno_slim subset: uberon_slim xref: EMAPA:27961 xref: EMAPA:28248 xref: FMA:84140 xref: GAID:430 xref: Glomerular:mesangium xref: http://www.snomedbrowser.com/Codes/Details/244574009 xref: MA:0002606 xref: MESH:A05.810.453.736.520.380 relationship: part_of UBERON:0002319 ! mesangium relationship: part_of UBERON:0004190 {source="GO"} ! renal glomerulus vasculature [Term] id: UBERON:0002321 name: extraglomerular mesangium namespace: uberon def: "the tissue comprised of mesangial cells that fill the triangular space between the macula densa and the afferent and efferent arterioles of the juxtaglomerular apparatus" [ISBN:0-683-40008-8, MP:0011340] subset: pheno_slim xref: EMAPA:28278 xref: FMA:84141 xref: MA:0002602 relationship: part_of UBERON:0002303 {source="MA"} ! juxtaglomerular apparatus relationship: part_of UBERON:0002319 {source="MA"} ! mesangium property_value: IAO:0000116 "check MA part_ofs - should be spatially disjoint from renal glomerulus?" xsd:string [Term] id: UBERON:0002325 name: epithelium of urethra namespace: uberon def: "The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.." [GO:0061071] synonym: "epithelial tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra epithelial tissue" EXACT [OBOL:automatic] synonym: "urethra epithelium" EXACT [] synonym: "urethral epithelium" RELATED [] synonym: "urethral plate" RELATED [EMAPA:31518] synonym: "urethral seam" RELATED [EMAPA:31518] xref: EMAPA:31518 xref: FMA:85275 xref: http://linkedlifedata.com/resource/umls/id/C1710584 xref: MA:0001686 xref: NCIT:C49309 xref: UMLS:C1710584 {source="ncithesaurus:Urethra_Epithelium"} is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0002326 name: lamina propria of urethra namespace: uberon def: "A lamina propria that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "lamina propria mucosa of urethra" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urethra" EXACT [OBOL:automatic] synonym: "urethra lamina propria" EXACT [] synonym: "urethra lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urethra lamina propria mucosae" EXACT [OBOL:automatic] synonym: "urethral lamina propria" RELATED [] xref: EMAPA:37785 {source="MA:th"} xref: FMA:85276 xref: MA:0001689 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0002335 name: macula densa namespace: uberon def: "The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]." [GO:0072024, http://en.wikipedia.org/wiki/Macula_densa] subset: pheno_slim subset: uberon_slim xref: BTO:0003940 xref: EMAPA:28399 xref: FMA:86333 xref: http://linkedlifedata.com/resource/umls/id/C0227662 xref: http://www.snomedbrowser.com/Codes/Details/244657003 xref: MA:0002603 xref: Macula:densa xref: NCIT:C33043 xref: UMLS:C0227662 {source="ncithesaurus:Macula_Densa"} is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0002303 {source="MA"} ! juxtaglomerular apparatus relationship: part_of UBERON:0004135 {source="GO"} ! distal tubule property_value: UBPROP:0000012 "not part of a nephron or distal tubule in MA and FMA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0002366 name: bulbo-urethral gland namespace: uberon def: "Any of the small paired racemose glands below the apex of the prostate in males, located posterolateral to the membranous portion of the urethra at the base of the penis, between the two layers of the fascia of the urogenital diaphragm, in the deep perineal pouch, and enclosed by transverse fibers of the sphincter urethrae membranaceae muscle; homologous to the greater vestibular (Bartholin's) glands in the female[MP]" [http://en.wikipedia.org/wiki/Bulbourethral_gland, MP:anna] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "bulbourethral gland" EXACT [FMA:9599] synonym: "Cowper's gland" EXACT [FMA:9599] synonym: "Cowper's gland of male" RELATED [EMAPA:19286] synonym: "Cowper's glands" EXACT PLURAL [FMA:9599] synonym: "glandula bulbourethralis" EXACT LATIN [MP:anna] synonym: "Mery's gland" EXACT [] synonym: "Méry gland" EXACT [MP:anna] xref: BTO:0001698 xref: Bulbourethral:gland xref: CALOHA:TS-0103 xref: EMAPA:19286 xref: FMA:9599 xref: GAID:387 xref: http://linkedlifedata.com/resource/umls/id/C0006366 xref: http://www.snomedbrowser.com/Codes/Details/278918009 xref: MA:0000401 xref: MESH:D002030 xref: NCIT:C32395 xref: UMLS:C0006366 {source="ncithesaurus:Cowper_s_Gland"} is_a: UBERON:0010186 ! male urethral gland property_value: depicted:by Male:anatomy.png xsd:anyURI property_value: UBPROP:0000001 "Either of two small racemose glands that are located below the prostate and discharge a component of the seminal fluid into the urethra. They are homologous to the Bartholin's glands in the female[BTO]." xsd:string {ontology="BTO", source="BTO:0001698"} property_value: UBPROP:0000001 "Lobular organ the parenchyma of which consists of glandular acini which communicate the bulbar part of the urethra. Examples: There only two instances, right and left bulbo-urethral glands[FMA]" xsd:string {ontology="FMA", source="FMA:9599"} property_value: UBPROP:0000010 "The bulbourethral glands are compound tubulo-alveolar glands." xsd:string property_value: UBPROP:0000012 "see comments for paraurethral gland - ncita placement may not be correct" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0003060 name: pronephric duct namespace: uberon def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]." [http://en.wikipedia.org/wiki/Pronephric_duct] comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] synonym: "ductus pronephricus" RELATED LATIN [http://en.wikipedia.org/wiki/Pronephric_duct] synonym: "pronephric ducts" RELATED PLURAL [ZFA:0000150] xref: AAO:0011088 xref: http://linkedlifedata.com/resource/umls/id/C1283945 xref: http://www.snomedbrowser.com/Codes/Details/361406002 xref: NCIT:C34279 xref: Pronephric:duct xref: TAO:0000150 xref: UMLS:C1283945 {source="ncithesaurus:Pronephric_Duct"} xref: VHOG:0000082 xref: XAO:0000063 xref: ZFA:0000150 is_a: UBERON:0009201 {source="GO"} ! nephric duct relationship: part_of UBERON:0002120 ! pronephros property_value: UBPROP:0000001 "Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000150", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686"} [Term] id: UBERON:0003074 name: mesonephric duct namespace: uberon def: "Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]." [http://en.wikipedia.org/wiki/Mesonephric_duct, https://github.com/obophenotype/uberon/issues/28, ZFIN:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "archinephric duct" RELATED [http://en.wikipedia.org/wiki/Wolffian_duct, VHOG:0000082] synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [http://en.wikipedia.org/wiki/Mesonephric_duct] synonym: "Leydig's duct" RELATED [http://en.wikipedia.org/wiki/Wolffian_duct] synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [GOC:yaf, http://en.wikipedia.org/wiki/Wolffian_duct, ZFA:0000546] xref: AAO:0000637 xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 xref: GAID:1315 xref: http://linkedlifedata.com/resource/umls/id/C0043204 xref: http://www.snomedbrowser.com/Codes/Details/308800003 xref: MESH:A16.254.940 xref: Mesonephric:duct xref: NCIT:C26469 xref: TAO:0000546 xref: UMLS:C0043204 {source="ncithesaurus:Mesonephric_Duct"} xref: VHOG:0000082 xref: XAO:0000242 xref: ZFA:0000546 is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0009201 {source="GO"} ! nephric duct property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png xsd:anyURI property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/rfoulger property_value: IAO:0000116 "Consider adding subclasses for male and female specific variants" xsd:string property_value: IAO:0000116 "TODO - mesonephric portion of the nephric duct" xsd:string property_value: UBPROP:0000001 "Anatomical structure consisting of either of a pair of longitudinal ducts which carry urine and in males, sperm, to the cloaca.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000637", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686"} property_value: UBPROP:0000011 "In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, seminal vesicle and efferent ducts." xsd:string [Term] id: UBERON:0003393 name: mesentery of urinary system namespace: uberon def: "A mesentery that is part of a urinary system [Automatically generated definition]." [OBOL:automatic] synonym: "excretory system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of excretory system" EXACT [OBOL:automatic] synonym: "mesentery of renal system" EXACT [OBOL:automatic] synonym: "mesentery of systema urinaria" EXACT [OBOL:automatic] synonym: "renal system mesentery" EXACT [OBOL:automatic] synonym: "systema urinaria mesentery" EXACT [OBOL:automatic] synonym: "urinary system mesentery" EXACT [OBOL:automatic] xref: EMAPA:17367 xref: MA:0003233 relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0003455 name: inner renal medulla loop of Henle namespace: uberon def: "A loop of Henle that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "kidney inner medulla loop of Henle" EXACT [MA:0002623] synonym: "loop of Henle, inner medullary portion" EXACT [EMAPA:28352] xref: EMAPA:28352 xref: MA:0002623 is_a: UBERON:0034997 ! renal medulla loop of Henle relationship: part_of UBERON:0001294 ! inner medulla of kidney [Term] id: UBERON:0003475 name: ureteric vein namespace: uberon def: "A vein that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "ureter vein" EXACT [OBOL:automatic] synonym: "vein of ureter" EXACT [OBOL:automatic] xref: EMAPA:37679 {source="MA:th"} xref: MA:0002250 relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0003517 name: kidney blood vessel namespace: uberon def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim subset: vertebrate_core synonym: "blood vessel of kidney" EXACT [OBOL:automatic] synonym: "renal blood vessel" EXACT [OBOL:automatic] xref: EMAPA:28457 xref: MA:0001682 xref: TAO:0005306 xref: ZFA:0005306 relationship: part_of UBERON:0006544 ! kidney vasculature [Term] id: UBERON:0003527 name: kidney capillary namespace: uberon def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "blood capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary vessel of kidney" EXACT [OBOL:automatic] synonym: "kidney blood capillary" EXACT [OBOL:automatic] synonym: "kidney capillary vessel" EXACT [OBOL:automatic] synonym: "renal capillary" EXACT [OBOL:automatic] xref: EMAPA:31443 xref: http://www.snomedbrowser.com/Codes/Details/275409003 xref: MA:0002586 is_a: UBERON:0003517 ! kidney blood vessel [Term] id: UBERON:0003546 name: distal convoluted tubule macula densa namespace: uberon def: "A macula densa that is part of a distal convoluted tubule [Automatically generated definition]." [OBOL:automatic] xref: MA:0001668 is_a: UBERON:0002335 ! macula densa relationship: part_of UBERON:0001292 {source="MA"} ! distal convoluted tubule [Term] id: UBERON:0003644 name: kidney arterial blood vessel namespace: uberon def: "An arterial blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "kidney arterial system" RELATED [EMAPA:31436] xref: EMAPA:31436 xref: MA:0002578 is_a: UBERON:0003517 ! kidney blood vessel [Term] id: UBERON:0003820 name: prostate bud namespace: uberon def: "A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]." [GO:0060513] synonym: "prostate ductal progenitor" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/18977204] synonym: "prostate gland bud" RELATED [EMAPA:36141] synonym: "prostate primordium" RELATED [] synonym: "prostatic bud" EXACT [] xref: EMAPA:36141 is_a: UBERON:0004902 ! urogenital sinus epithelium property_value: UBPROP:0000009 "AR activation releases instructive signals from UGM that acts on UGS epithelium (UGE) to stimulate cell proliferation, form prostate ductal progenitors (prostatic buds), and regulate cell adhesion dynamics to permit prostatic bud outgrowth. There are three phases of prostatic budding: (1) the specification phase, when instructive developmental cues define where buds will form in the UGS, (2) the initiation phase, when prostatic buds begin to form, and (3) the elongation phase, when proliferation, cell adhesion, and cell migration coordinate outgrowth of prostatic buds into UGM. Timing of prostatic bud formation and the quantity and pattern of buds that are formed in the UGS are strictly regulated [3, 4]. The position of prostatic buds as they emerge from the UGS in utero determines the arrangement of prostate ducts in adulthood.[PMID:18977204]" xsd:string [Term] id: UBERON:0003829 name: urethra muscle tissue namespace: uberon def: "Any muscle tissue that is part of the urethra." [UBERON:cjm] synonym: "urethral muscle layer" RELATED [MA:0002649] xref: EMAPA:37787 {source="MA:th"} xref: MA:0002649 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0004032 name: podocyte slit diaphragm namespace: uberon def: "The thin membrane that covers the podocyte filtration slit which allows small molecules such as water, glucose, and ionic salts to pass through while retaining larger macromolecules in the bloodstream" [MP:0008060] subset: pheno_slim relationship: part_of CL:0000653 ! glomerular visceral epithelial cell property_value: IAO:0000116 "TODO - submit to GO" xsd:string [Term] id: UBERON:0004033 name: podocyte slit junction namespace: uberon def: "The gaps between the interdigitated foot processes of the podocyte" [MP:0008062] subset: pheno_slim relationship: part_of CL:0000653 ! glomerular visceral epithelial cell property_value: IAO:0000116 "TODO - submit to GO" xsd:string [Term] id: UBERON:0004100 name: renal collecting system namespace: uberon def: "The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone." [HP:0004742, http://en.wikipedia.org/wiki/Collecting_duct_system] subset: pheno_slim synonym: "collecting duct system" EXACT [http://en.wikipedia.org/wiki/Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [http://en.wikipedia.org/wiki/Collecting_duct_system] synonym: "tubulus renalis colligens" RELATED LATIN [http://en.wikipedia.org/wiki/Collecting_duct_system] xref: FMA:265239 xref: http://en.wikipedia.org/wiki/Collecting_duct_system xref: http://www.snomedbrowser.com/Codes/Details/279371005 is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002113 ! kidney property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0004134 name: proximal tubule namespace: uberon def: "In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]." [GO:0072014] synonym: "kidney proximal tubule" EXACT [MA:0002611] synonym: "proximal kidney tubule" EXACT [MESH:A05.810.453.736.560.570] synonym: "renal proximal tubule" EXACT [] xref: BTO:0001498 xref: CALOHA:TS-0509 xref: EMAPA:28281 xref: MA:0002611 xref: MESH:D007687 is_a: UBERON:0006853 ! renal cortex tubule property_value: IAO:0000116 "TODO - ensure definition works across species." xsd:string [Term] id: UBERON:0004135 name: distal tubule namespace: uberon def: "The distal tubule is a nephron tubule that consists of the distal convoluted tubule and distal straight tubule segments" [GO:0072017] synonym: "kidney distal tubule" EXACT [MA:0002633] synonym: "renal distal tubule" EXACT [] xref: BTO:0000482 xref: CALOHA:TS-0504 xref: EMAPA:28387 xref: MA:0002633 xref: MESH:D007686 is_a: UBERON:0007685 ! region of nephron tubule [Term] id: UBERON:0004136 name: intermediate tubule namespace: uberon def: "The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules" [GO:0072018] synonym: "renal intermediate tubule" EXACT [] synonym: "tubulus attenuatus" EXACT [FMA:17718] xref: FMA:17718 is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001288 {source="FMA"} ! loop of Henle property_value: IAO:0000116 "TODO - check for applicability across species" xsd:string [Term] id: UBERON:0004188 name: glomerular epithelium namespace: uberon def: "The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GO:0072010] synonym: "epithelium of glomerulus" EXACT [] synonym: "epithelium of kidney glomerulus" EXACT [] synonym: "epithelium of renal glomerulus" EXACT [] synonym: "glomerular epithelial cell" RELATED [BTO:0001515] synonym: "kidney glomerular epithelium" EXACT [MA:0002847] xref: BTO:0001515 xref: EMAPA:35458 xref: MA:0002847 is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0000074 ! renal glomerulus property_value: IAO:0000116 "TODO - check - GO says outer, BTO says inner. Make this a superclass" xsd:string [Term] id: UBERON:0004189 name: glomerular endothelium namespace: uberon def: "The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus" [GO:0072011] synonym: "endothelium of renal glomerulus" EXACT [OBOL:automatic] synonym: "renal glomerulus endothelium" EXACT [OBOL:automatic] xref: BTO:0004631 is_a: UBERON:0004188 ! glomerular epithelium relationship: part_of UBERON:0004190 ! renal glomerulus vasculature [Term] id: UBERON:0004190 name: renal glomerulus vasculature namespace: uberon def: "The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus" [GO:0072012] synonym: "glomerulus vasculature" EXACT [OBOL:automatic] synonym: "renal glomerulus vascular network" EXACT [OBOL:automatic] synonym: "renal glomerulus vasculature" EXACT [OBOL:automatic] synonym: "vascular network of renal glomerulus" EXACT [OBOL:automatic] synonym: "vasculature of renal glomerulus" EXACT [OBOL:automatic] is_a: UBERON:0006544 ! kidney vasculature relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0004193 name: loop of Henle ascending limb thin segment namespace: uberon def: "A sub-portion of the loop of Henle in the nephron of the kidney that is permeable to ions but not to water" [GO:0072021, http://en.wikipedia.org/wiki/Thin_ascending_limb_of_loop_of_Henle] subset: pheno_slim synonym: "ascending limb thin segment of loop of Henle" EXACT [] synonym: "ascending thin limb" EXACT [FMA:17720] synonym: "pars ascendens (tubulus attenuatus)" EXACT [FMA:17720] synonym: "thin ascending limb" EXACT [EMAPA:28328] synonym: "thin ascending limb of loop of Henle" EXACT [] xref: EMAPA:28328 xref: EMAPA:28361 xref: FMA:17720 xref: http://en.wikipedia.org/wiki/Thin_ascending_limb_of_loop_of_Henle xref: MA:0001678 is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0003455 ! inner renal medulla loop of Henle relationship: part_of UBERON:0005164 ! ascending limb of loop of Henle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI property_value: IAO:0000116 "check relationship to distal tubule" xsd:string [Term] id: UBERON:0004194 name: long nephron namespace: uberon def: "Long nephrons are associated with juxtamedullary glomeruli and extend to the inner medulla" [GO:0072029] synonym: "juxtamedullary nephron" RELATED [GO:0072029, http://sourceforge.net/tracker/?func=detail&aid=3031362&group_id=36855&atid=440764] xref: FMA:272054 xref: http://linkedlifedata.com/resource/umls/id/C1517630 xref: NCIT:C32892 xref: UMLS:C1517630 {source="ncithesaurus:Juxtamedullary_Nephron"} is_a: UBERON:0001285 ! nephron [Term] id: UBERON:0004195 name: short nephron namespace: uberon def: "Short nephrons are associated with mid-cortical glomeruli, and have no short ascending limb, so the limb is situated in the outer medulla" [GO:0072030] xref: FMA:272051 is_a: UBERON:0001285 ! nephron [Term] id: UBERON:0004196 name: proximal convoluted tubule segment 1 namespace: uberon alt_id: UBERON:0006432 def: "The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]." [GO:0072031, http://sourceforge.net/tracker/?func=detail&atid=440764&aid=3298740&group_id=36855] synonym: "proximal tubule segment 1" EXACT [MA:0002612] synonym: "S1" BROAD [GO:0072031] synonym: "S1 portion of renal tubule" EXACT [] synonym: "S1 portion of tubule" EXACT [] synonym: "segment 1 of proximal tubule" EXACT [EMAPA:29657] xref: EMAPA:29657 xref: MA:0002612 is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0001287 {source="GO"} ! proximal convoluted tubule [Term] id: UBERON:0004197 name: proximal convoluted tubule segment 2 namespace: uberon alt_id: UBERON:0006433 def: "The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO]." [GO:0072032] synonym: "proximal tubule segment 2" EXACT [MA:0002613] synonym: "S2" BROAD [GO:0072032] synonym: "S2 portion of renal tubule" EXACT [] synonym: "S2 portion of tubule" EXACT [] synonym: "segment 2 of proximal tubule" EXACT [EMAPA:29659] xref: EMAPA:29659 xref: MA:0002613 is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0001287 {source="GO"} ! proximal convoluted tubule [Term] id: UBERON:0004198 name: comma-shaped body namespace: uberon def: "The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron" [GO:0072049] subset: pheno_slim synonym: "CSB" EXACT ABBREVIATION [] xref: EMAPA:27681 xref: ZFA:0005588 relationship: part_of UBERON:0010532 {source="cjm"} ! primitive nephron [Term] id: UBERON:0004199 name: S-shaped body namespace: uberon def: "The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron" [GO:0072050] subset: pheno_slim synonym: "SSB" EXACT ABBREVIATION [] synonym: "stage II nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html] xref: EMAPA:27756 xref: ZFA:0005589 relationship: part_of UBERON:0010532 {source="cjm"} ! primitive nephron property_value: IAO:0000116 "TODO" xsd:string [Term] id: UBERON:0004200 name: kidney pyramid namespace: uberon alt_id: UBERON:0002449 alt_id: UBERON:0005098 def: "Kidney pyramids are the conical arrangements of tubules that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts." [GO:0072056, http://anatomy.uams.edu/anatomyhtml/kidney.html] subset: pheno_slim synonym: "Malphigian pyramid" RELATED MISSPELLING [BTO:0003926] synonym: "Malpighian pyramid" EXACT [http://en.wikipedia.org/wiki/Renal_pyramids] synonym: "Malpighian pyramid" RELATED [] synonym: "medullary pyramid" RELATED [] synonym: "pyramid" BROAD [GO:0072056] synonym: "pyramid of Malphigi" RELATED MISSPELLING [ncithesaurus:Pyramid_of_Malpighi] synonym: "pyramid of Malpighi" RELATED [UBERON:cjm] synonym: "pyramides renales" RELATED LATIN [http://en.wikipedia.org/wiki/Renal_pyramids] synonym: "pyramis renalis" RELATED [BTO:0003926] synonym: "renal medullary region" RELATED [FMA:258870] synonym: "renal pyramid" EXACT [http://en.wikipedia.org/wiki/Renal_pyramids] xref: BTO:0003926 xref: FMA:258870 xref: http://linkedlifedata.com/resource/umls/id/C0227629 xref: http://linkedlifedata.com/resource/umls/id/C1514613 xref: http://www.snomedbrowser.com/Codes/Details/361328001 xref: MA:0001654 xref: NCIT:C12886 xref: NCIT:C33436 xref: Renal:pyramids xref: UMLS:C0227629 {source="ncithesaurus:Renal_Pyramid"} xref: UMLS:C1514613 {source="ncithesaurus:Pyramid_of_Malpighi"} relationship: part_of UBERON:0000362 ! renal medulla property_value: depicted:by Kidney:PioM.png xsd:anyURI property_value: UBPROP:0000012 "not the same as FMA:50609 Pyramid (which is a volume / dimensional entity)" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000202 FMA:74268 [Term] id: UBERON:0004201 name: kidney outer medulla inner stripe namespace: uberon def: "The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thick and thin portions of nephron tubules" [GO:0072057] subset: pheno_slim synonym: "inner stripe" EXACT [GO:0072057] synonym: "inner stripe of medulla of kidney" EXACT [FMA:76663] synonym: "inner stripe of outer medulla" EXACT [EMAPA:29675] synonym: "inner stripe of renal medulla" EXACT [FMA:76663] synonym: "outer medulla inner stripe" EXACT [MA:0002626] synonym: "stria interna medullae renalis" EXACT LATIN [FMA:76663, FMA:TA] xref: EMAPA:29675 xref: FMA:76663 xref: MA:0002626 relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0004202 name: kidney outer medulla outer stripe namespace: uberon def: "The outer stripe is the region of the kidney that lies distal to the line of termination of the straight renal tubules" [GO:0072058] subset: pheno_slim synonym: "outer medulla outer stripe" EXACT [MA:0002629] synonym: "outer stripe" EXACT [GO:0072058] synonym: "outer stripe of medulla of kidney" EXACT [FMA:76662] synonym: "outer stripe of outer medulla" EXACT [EMAPA:29663] synonym: "outer stripe of renal medulla" EXACT [FMA:76662] synonym: "stria externa medullae renalis" EXACT LATIN [FMA:76662, FMA:TA] xref: EMAPA:29663 xref: FMA:76662 xref: MA:0002629 relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0004203 name: cortical collecting duct namespace: uberon alt_id: UBERON:0005267 def: "The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex" [GO:0072059] synonym: "kidney cortex collecting duct" EXACT [MA:0002600] synonym: "renal cortex collecting duct" RELATED [MA:0002600] xref: BTO:0002643 xref: EMAPA:28130 xref: MA:0002600 relationship: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: UBERON:0004204 name: outer medullary collecting duct namespace: uberon alt_id: UBERON:0005186 def: "The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla" [GO:0072060] synonym: "kidney outer medulla collecting duct" EXACT [MA:0002599] synonym: "outer renal medulla collecting duct" EXACT [MA:0002599] xref: EMAPA:28346 xref: MA:0002599 is_a: UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0004205 name: inner medullary collecting duct namespace: uberon alt_id: UBERON:0005187 def: "The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla" [GO:0072061] synonym: "inner renal medulla collecting duct" EXACT [MA:0002598] synonym: "kidney inner medulla collecting duct" EXACT [MA:0002598] synonym: "papillary collecting duct" RELATED [MA:0002598] xref: BTO:0004544 xref: EMAPA:28370 xref: MA:0002598 is_a: UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001294 ! inner medulla of kidney [Term] id: UBERON:0004206 name: long descending thin limb bend namespace: uberon def: "The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment" [GO:0072065] is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0001289 ! descending limb of loop of Henle [Term] id: UBERON:0004207 name: prebend segment of loop of Henle namespace: uberon def: "The prebend segment is a part of the descending thin limb that lies before the bend and exhibits robust sodium chloride reabsorption" [GO:0072066] synonym: "prebend segment" RELATED [GO:0072066] is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0001289 ! descending limb of loop of Henle relationship: part_of UBERON:0005096 {source="GO"} ! descending thin limb [Term] id: UBERON:0004211 name: nephron epithelium namespace: uberon def: "The nephron epithelium is a tissue that covers the surface of a nephron" [GO:0072088] synonym: "epithelial tissue of nephron" EXACT [OBOL:automatic] synonym: "epithelium of nephron" EXACT [OBOL:automatic] synonym: "nephron epithelial tissue" EXACT [OBOL:automatic] is_a: UBERON:0004819 ! kidney epithelium relationship: part_of UBERON:0001285 ! nephron [Term] id: UBERON:0004212 name: glomerular capillary namespace: uberon def: "the small branching blood vessels in the kidney glomerulus that receives blood from the kidney afferent arterioles; these capillaries are under high pressure for filtering within the glomerulus" [MGI:csmith, MP:0011320] subset: pheno_slim subset: vertebrate_core synonym: "blood capillary of renal glomerulus" EXACT [OBOL:automatic] synonym: "capillary of renal glomerulus" EXACT [OBOL:automatic] synonym: "capillary vessel of renal glomerulus" EXACT [OBOL:automatic] synonym: "glomerular capillaries" RELATED PLURAL [] synonym: "glomerular capillary system" RELATED [MA:0002587] synonym: "renal glomerulus blood capillary" EXACT [OBOL:automatic] synonym: "renal glomerulus capillary" EXACT [OBOL:automatic] synonym: "renal glomerulus capillary vessel" EXACT [OBOL:automatic] xref: EMAPA:28245 xref: FMA:274259 xref: http://linkedlifedata.com/resource/umls/id/C0226356 xref: http://www.snomedbrowser.com/Codes/Details/362049007 xref: MA:0002587 xref: NCIT:C32684 xref: TAO:0005284 xref: UMLS:C0226356 {source="ncithesaurus:Glomerular_Capillary"} xref: ZFA:0005284 is_a: UBERON:0003527 ! kidney capillary relationship: part_of UBERON:0004190 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! renal glomerulus vasculature property_value: UBPROP:0000001 "Capillary that is part of the renal glomerulus. Glomerular capillary endothelial membranes in zebrafish normally have a fenestrated morphology that is visible at the ultrastructural level.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005284", ontology="TAO", source="ZFIN:ZDB-PUB-000824-1", source="ZFIN:curator"} [Term] id: UBERON:0004219 name: urethra smooth muscle layer namespace: uberon def: "A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of urethra" EXACT [FMA:76909] synonym: "muscular coat of urethra" EXACT [FMA:76909] synonym: "muscular layer of urethra" EXACT [FMA:76909] synonym: "smooth muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "tunica muscularis urethrae" EXACT LATIN [FMA:TA] synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urethral smooth muscle" RELATED [MA:0001691] xref: EMAPA:36630 xref: FMA:76909 xref: MA:0001691 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0004227 name: kidney pelvis smooth muscle namespace: uberon def: "the smooth muscle tissue surrounding the urothelium of the kidney pelvis" [MGI:csmith, MP:0011335] subset: pheno_slim synonym: "kidney pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "pelvic smooth muscle" RELATED [EMAPA:28120] synonym: "renal pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "smooth muscle tissue of renal pelvis" EXACT [FMA:262022] xref: EMAPA:28120 xref: FMA:262022 xref: MA:0002631 relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0004228 name: urinary bladder smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle layer of bladder" RELATED [] synonym: "smooth muscle of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder" EXACT [OBOL:automatic] synonym: "urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder muscle" EXACT [MA:0001697] synonym: "urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001849 xref: CALOHA:TS-1087 xref: EMAPA:37791 {source="MA:th"} xref: MA:0001697 relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: UBERON:0004229 name: urinary bladder trigone smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "deep trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "deep trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "deep trigone smooth muscle" EXACT [OBOL:automatic] synonym: "deep trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of deep trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone smooth muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of deep trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of deep trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of deep trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of trigone of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder smooth muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder smooth muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urinary bladder trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder trigone muscle" EXACT [MA:0001700] synonym: "urinary bladder trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vesical trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "vesical trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "vesical trigone smooth muscle" EXACT [OBOL:automatic] synonym: "vesical trigone smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:28649 xref: MA:0001700 is_a: UBERON:0004228 ! urinary bladder smooth muscle relationship: part_of UBERON:0001257 ! trigone of urinary bladder [Term] id: UBERON:0004230 name: urinary bladder neck smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "neck of urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vesical neck" EXACT [OBOL:automatic] synonym: "trigonal muscle" EXACT [FMA:67990] synonym: "trigonal muscle of urinary bladder" EXACT [FMA:67990] synonym: "urinary bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck muscle" EXACT [MA:0001699] synonym: "urinary bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vesical neck involuntary muscle" EXACT [OBOL:automatic] synonym: "vesical neck non-striated muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:30123 xref: FMA:67990 xref: MA:0001699 is_a: UBERON:0004228 ! urinary bladder smooth muscle relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0004294 name: glomerular capillary endothelium namespace: uberon def: "An endothelium that is part of a glomerular capillary." [OBOL:automatic] subset: pheno_slim synonym: "renal glomerulus capillary endothelium" EXACT [OBOL:automatic] xref: http://linkedlifedata.com/resource/umls/id/C0227647 xref: http://www.snomedbrowser.com/Codes/Details/243993006 xref: MA:0001658 xref: NCIT:C32522 xref: UMLS:C0227647 {source="ncithesaurus:Endothelium_of_the_Glomerular_Capillary"} is_a: UBERON:0004189 ! glomerular endothelium relationship: part_of UBERON:0004212 ! glomerular capillary [Term] id: UBERON:0004538 name: left kidney namespace: uberon def: "A kidney that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:36589 xref: FMA:7205 xref: http://linkedlifedata.com/resource/umls/id/C0227614 xref: http://www.snomedbrowser.com/Codes/Details/362209008 xref: MA:0001655 xref: NCIT:C34006 xref: UMLS:C0227614 {source="ncithesaurus:Left_Kidney"} is_a: UBERON:0002113 ! kidney property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI [Term] id: UBERON:0004539 name: right kidney namespace: uberon def: "A kidney that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:36590 xref: FMA:7204 xref: http://linkedlifedata.com/resource/umls/id/C0227613 xref: http://www.snomedbrowser.com/Codes/Details/362208000 xref: MA:0001683 xref: NCIT:C34005 xref: UMLS:C0227613 {source="ncithesaurus:Right_Kidney"} is_a: UBERON:0002113 ! kidney property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI [Term] id: UBERON:0004639 name: renal afferent arteriole namespace: uberon def: "the blood vessels that branch from the kidney interlobular artery, convey blood to the glomerular capillaries, and play an important role in the regulation of blood pressure as a part of the tubuloglomerular feedback mechanism" [ISBN:0-683-40008-8, MGI:csmith, MP:0011312] subset: pheno_slim subset: vertebrate_core synonym: "afferent arteriole" EXACT [MA:0002579] synonym: "afferent glomerular arteriole" EXACT [ZFA:0005307] synonym: "afferent glomerular arteriole of kidney" EXACT [FMA:77042] synonym: "arteriola glomerularis afferens" RELATED LATIN [http://en.wikipedia.org/wiki/Afferent_arterioles] synonym: "arteriola glomerularis afferens renis" EXACT LATIN [FMA:77042, FMA:TA] synonym: "kidney afferent arteriole" EXACT [MP:0011312] xref: Afferent:arterioles xref: EMAPA:28230 xref: EMAPA:28266 xref: FMA:77042 xref: http://www.snomedbrowser.com/Codes/Details/67498004 xref: MA:0002579 xref: TAO:0002139 xref: ZFA:0005307 is_a: UBERON:0003644 ! kidney arterial blood vessel relationship: part_of UBERON:0001229 ! renal corpuscle relationship: part_of UBERON:0004723 ! interlobular artery property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0004640 name: renal efferent arteriole namespace: uberon def: "the blood vessels that convey blood from the glomerulocapillary network to the capillary bed of the proximal convoluted tubule" [ISBN:0-683-40008-8, MGI:csmith, MP:0011313] subset: pheno_slim subset: vertebrate_core synonym: "arteriola glomerularis efferens capsulae renalis" RELATED LATIN [http://en.wikipedia.org/wiki/Efferent_arteriole] synonym: "arteriola glomerularis efferens renis" EXACT LATIN [FMA:77043, FMA:TA] synonym: "efferent arteriole" EXACT [MA:0002585] synonym: "efferent glomerular arteriole" EXACT [ZFA:0005308] synonym: "efferent glomerular arteriole of kidney" EXACT [FMA:77043] synonym: "kidney efferent arteriole" EXACT [MP:0011313] xref: Efferent:arteriole xref: EMAPA:28233 xref: EMAPA:28275 xref: FMA:77043 xref: http://www.snomedbrowser.com/Codes/Details/29926005 xref: MA:0002585 xref: TAO:0002140 xref: ZFA:0005308 is_a: UBERON:0003644 ! kidney arterial blood vessel relationship: part_of UBERON:0001229 ! renal corpuscle property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0004645 name: urinary bladder urothelium namespace: uberon def: "The epithelial lining of the luminal space of the urinary bladder." [MP:0000540] subset: pheno_slim synonym: "bladder transitional cell epithelium" EXACT [FMA:15936] synonym: "epithelium of bladder" RELATED [EMAPA:28601] synonym: "transitional epithelium" RELATED [MA:0001693] synonym: "transitional epithelium of urinary bladder" EXACT [FMA:15936] synonym: "urinary bladder transitional epithelium" EXACT [FMA:15936] synonym: "urothelium" BROAD [BTO:0001245] synonym: "urothelium of urinary bladder" EXACT [FMA:15936] xref: BTO:0001694 xref: CALOHA:TS-1088 xref: EMAPA:28601 xref: FMA:15936 xref: http://linkedlifedata.com/resource/umls/id/C0225339 xref: http://www.snomedbrowser.com/Codes/Details/25631003 xref: MA:0001693 xref: NCIT:C13318 xref: UMLS:C0225339 {source="ncithesaurus:Transitional_Epithelium"} is_a: UBERON:0000365 ! urothelium relationship: part_of UBERON:0001259 ! mucosa of urinary bladder property_value: UBPROP:0000010 "5-7 cell layers thick in contracted bladder, 2-3 cells thick in distended bladder; lines renal pelvis, ureters, bladder, most of urethra but not distal urethra" xsd:string [Term] id: UBERON:0004719 name: kidney arcuate vein namespace: uberon def: "Any of the veins that parallel the arcuate arteries, receive blood from the interlobular veins and straight venules, and terminate in the interlobar veins." [ISBN:0-683-40008-8, MP:0011325] subset: pheno_slim synonym: "arciform vein of kidney" EXACT [MP:0011325] synonym: "arcuate vein" BROAD [MA:0002593] synonym: "arcuate vein of kidney" EXACT [MP:0011325] synonym: "arcuate veins" RELATED [http://en.wikipedia.org/wiki/Arcuate_vein] synonym: "renal arcuate vein" EXACT [MP:0011325] synonym: "venae arcuatae renis" EXACT LATIN [http://en.wikipedia.org/wiki/Arcuate_vein] xref: Arcuate:vein xref: EMAPA:28221 xref: FMA:272193 xref: FMA:321527 xref: MA:0002593 is_a: UBERON:0014401 ! renal venous blood vessel property_value: depicted:by Kidney:PioM.png xsd:anyURI property_value: UBPROP:0000202 FMA:71632 [Term] id: UBERON:0004723 name: interlobular artery namespace: uberon def: "The branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule." [http://en.wikipedia.org/wiki/Interlobular_arteries, MP:0011316] subset: pheno_slim synonym: "arteriae corticales radiatae" RELATED LATIN [http://en.wikipedia.org/wiki/Interlobular_arteries] synonym: "arteriae interlobulares renis" RELATED LATIN [http://en.wikipedia.org/wiki/Interlobular_arteries] synonym: "cortical radial arteries" RELATED [http://en.wikipedia.org/wiki/Interlobular_arteries] synonym: "interlobular" RELATED [http://en.wikipedia.org/wiki/Interlobular_arteries] synonym: "interlobular renal artery" EXACT [FMA:70498] synonym: "kidney interlobular artery" EXACT [MP:0011316] synonym: "renal interlobular artery" RELATED [FMA:70498] xref: EMAPA:28212 xref: FMA:70498 xref: http://linkedlifedata.com/resource/umls/id/C1512856 xref: http://www.snomedbrowser.com/Codes/Details/76147008 xref: Interlobular:arteries xref: MA:0002584 xref: NCIT:C32826 xref: UMLS:C1512856 {source="ncithesaurus:Interlobular_Artery"} is_a: UBERON:0003644 ! kidney arterial blood vessel property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0004736 name: metanephric glomerulus namespace: uberon def: "glomerulus of the mature vertebrate kidney, or metanephros." [GO:0072224] synonym: "glomerulus of metanephros" EXACT [] xref: VHOG:0001242 is_a: UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0004737 name: metanephric collecting duct namespace: uberon def: "A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]." [OBOL:automatic] synonym: "collecting duct of metanephros" EXACT [] synonym: "metanephric collecting tubule" RELATED [VHOG:0000983] xref: VHOG:0000983 is_a: UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0004738 name: metanephric juxtaglomerular apparatus namespace: uberon def: "juxtaglomerular apparatus of the mature vertebrate kidney, or metanephros." [GO:0072206] synonym: "juxtaglomerular apparatus of metanephros" EXACT [] is_a: UBERON:0002303 ! juxtaglomerular apparatus relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0004739 name: pronephric glomerulus namespace: uberon alt_id: UBERON:0004191 def: "The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment." [GO:0072013, GOC:mtg_kidney_jan10, http://www.ncbi.nlm.nih.gov/pubmed/10572058, http://www.ncbi.nlm.nih.gov/pubmed/15647339, http://www.ncbi.nlm.nih.gov/pubmed/9268568, https://doi.org/10.1371/journal.pone.0099864, XAO:0000318] synonym: "corpuscle" RELATED [XAO:0000318] synonym: "glomera" RELATED PLURAL [XAO:0000318] synonym: "glomerulus of pronephros" EXACT [] synonym: "glomus" NARROW [XAO:0000318] synonym: "pronephric glomera" RELATED [VHOG:0001237] synonym: "pronephric glomeruli" RELATED PLURAL [VHOG:0001237] synonym: "pronephric glomus" RELATED [VHOG:0001237] xref: AAO:0011049 xref: http://www.snomedbrowser.com/Codes/Details/360548001 xref: TAO:0001557 xref: VHOG:0001237 xref: XAO:0000318 xref: ZFA:0001557 is_a: UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0002120 ! pronephros property_value: IAO:0000232 "a glomus differs from a glomerulus in that each vascular glomus services several tubules" xsd:string {source="ISBN:0073040584"} property_value: UBPROP:0000001 "Paired highly vascularized portion of the pronephros. Left and right glomeruli are fused at the midline. Begins to function between 40 and 48hpf. Drummond, 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001557", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The teleost pronephros shares many essential features with the amphibian pronephros including its derivation from mesoderm associated with the coelom and the derivation of the glomerular blood supply from the medial dorsal aorta. However, unlike the pronephros of amphibians, which have an external glomus and tubules with nephrostomes open to the coelom, the mature teleost pronephros has no connection to the body cavity and instead functions as a closed system (reference 1); This variation in nephron types [with external glomeruli that open into the coelom and with internal glomeruli that do not connect with the coelom] and their pattern of distribution suggest an evolutionary sequence. Ancestral craniates probably had an external glomerulus and nephrostomes, as do the first few to develop in very primitive craniates. (...) The mechanism would become more efficient as the coelomic recess into which each glomerulus discharged became a part of the tubule, that is, grew around the glomerulus as a renal capsule. The glomerulus becomes internal. The nephrostomes were lost during subsequent evolution, leaving the type of renal tubule found in most vertebrates (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001237", ontology="VHOG", source="http://bgee.unil.ch/", source="PMID:9806915 Drummond IA, Majumdar A, Hentschel H, Elger M, Solnica-Krezel L, Schier AF, Neuhauss SCF, Stemple DL, Zwartkruis F, Rangini Z, Driever W, Fishman MC, Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.636"} property_value: UBPROP:0000012 "GO treats glomus and pronephric glomerulus differently" xsd:string {external_ontology="GO"} [Term] id: UBERON:0004775 name: outer renal medulla vasa recta namespace: uberon def: "A vasa recta that is part of a outer medulla of kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "kidney outer medulla vasa recta" EXACT [MP:0011330] synonym: "kidney outer renal medulla vasa recta" EXACT [MP:0011330] synonym: "outer medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "outer zone of medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "outer zone of renal medulla vasa recta" EXACT [OBOL:automatic] synonym: "vasa recta of outer medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of outer renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of outer zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of outer zone of renal medulla" EXACT [OBOL:automatic] xref: EMAPA:36560 xref: MA:0002597 is_a: UBERON:0014401 ! renal venous blood vessel relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0004776 name: inner renal medulla vasa recta namespace: uberon def: "A vasa recta that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "inner medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "inner zone of medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "inner zone of renal medulla vasa recta" EXACT [OBOL:automatic] synonym: "set of inner region of renal pyramids vasa recta" EXACT [OBOL:automatic] synonym: "vasa recta of inner medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of inner renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of inner zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of inner zone of renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of set of inner region of renal pyramids" EXACT [OBOL:automatic] xref: EMAPA:36559 xref: MA:0002596 is_a: UBERON:0014401 ! renal venous blood vessel relationship: part_of UBERON:0001294 ! inner medulla of kidney [Term] id: UBERON:0004787 name: urethra urothelium namespace: uberon def: "An urothelium that is part of a urethra [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "urethra uroepithelium" EXACT [OBOL:automatic] synonym: "uroepithelium of urethra" EXACT [OBOL:automatic] synonym: "urothelium of urethra" EXACT [OBOL:automatic] xref: EMAPA:35896 xref: http://linkedlifedata.com/resource/umls/id/C1710585 xref: MA:0001687 xref: NCIT:C49310 xref: UMLS:C1710585 {source="ncithesaurus:Urethra_Transitional_Cell_Epithelium"} is_a: UBERON:0000365 ! urothelium is_a: UBERON:0002325 ! epithelium of urethra [Term] id: UBERON:0004788 name: kidney pelvis urothelium namespace: uberon def: "the epithelial lining of the luminal space of the kidney pelvis" [MGI:csmith, MP:0011336] subset: pheno_slim synonym: "kidney pelvis transitional epithelium" EXACT [OBOL:automatic] synonym: "kidney pelvis uroepithelium" EXACT [OBOL:automatic] synonym: "pelvic urothelium" RELATED [EMAPA:28077] synonym: "pelvis of ureter uroepithelium" EXACT [OBOL:automatic] synonym: "pelvis of ureter urothelium" EXACT [OBOL:automatic] synonym: "renal pelvis transitional epithelium" EXACT [OBOL:automatic] synonym: "renal pelvis uroepithelium" EXACT [OBOL:automatic] synonym: "renal pelvis urothelium" EXACT [OBOL:automatic] synonym: "transitional epithelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "transitional epithelium of renal pelvis" EXACT [FMA:263264] synonym: "uroepithelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "uroepithelium of pelvis of ureter" EXACT [OBOL:automatic] synonym: "uroepithelium of renal pelvis" EXACT [OBOL:automatic] synonym: "urothelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "urothelium of pelvis of ureter" EXACT [OBOL:automatic] synonym: "urothelium of renal pelvis" EXACT [OBOL:automatic] xref: EMAPA:28077 xref: FMA:263264 xref: http://linkedlifedata.com/resource/umls/id/C1709899 xref: MA:0002632 xref: NCIT:C54556 xref: UMLS:C1709899 {source="ncithesaurus:Renal_Pelvis_Urothelium"} is_a: UBERON:0000365 ! urothelium is_a: UBERON:0004819 ! kidney epithelium relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0004810 name: nephron tubule epithelium namespace: uberon def: "the cellular avascular layer of the renal tubule luminar surfaces" [MGI:csmith, MP:0009640] subset: pheno_slim synonym: "kidney tubule epithelium" EXACT [MA:0001681] xref: BTO:0005239 xref: EMAPA:36524 xref: http://linkedlifedata.com/resource/umls/id/C1709902 xref: MA:0001681 xref: NCIT:C49276 xref: UMLS:C1709902 {source="ncithesaurus:Renal_Tubule_Epithelium"} is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001231 ! nephron tubule property_value: IAO:0000116 "See https://github.com/obophenotype/uberon/issues/1305" xsd:string [Term] id: UBERON:0004819 name: kidney epithelium namespace: uberon def: "the cellular avascular layer of the kidney luminar surfaces" [MGI:csmith, MP:0004967] subset: pheno_slim synonym: "epithelial tissue of kidney" EXACT [OBOL:automatic] synonym: "epithelium of kidney" EXACT [OBOL:automatic] synonym: "kidney epithelial tissue" EXACT [OBOL:automatic] synonym: "renal epithelium" RELATED [EMAPA:35457] xref: BTO:0000059 xref: CALOHA:TS-0505 xref: EMAPA:35457 xref: MA:0002846 relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0004829 name: urethra skeletal muscle tissue namespace: uberon def: "A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle of urethra" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra skeletal muscle" RELATED [MA:0001690] synonym: "urethra skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "urethral skeletal muscle" RELATED [MA:0001690] xref: EMAPA:37788 {source="MA:th"} xref: MA:0001690 relationship: part_of UBERON:0003829 ! urethra muscle tissue [Term] id: UBERON:0004902 name: urogenital sinus epithelium namespace: uberon def: "The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra" [http://www.ncbi.nlm.nih.gov/pubmed/18977204] synonym: "epithelium of urogenital sinus" EXACT [OBOL:automatic] synonym: "UGE" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/18977204] xref: EHDAA2:0004061 xref: EMAPA:31509 is_a: UBERON:0009846 ! embryonic cloacal epithelium relationship: part_of UBERON:0000164 ! primitive urogenital sinus property_value: UBPROP:0000012 "we follow EHDAA2 in dividing the UGS into epithelium and lumen" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0004917 name: urethral sphincter namespace: uberon def: "A sphincter muscle surrounding the urethra." [http://en.wikipedia.org/wiki/Urethral_sphincter] synonym: "sphincter muscle of urethra" EXACT [] synonym: "sphincter of urethra" EXACT [] synonym: "sphincter urethrae" EXACT [] synonym: "urethral sphincter muscle" EXACT [] xref: EMAPA:37789 {source="MA:th"} xref: http://www.snomedbrowser.com/Codes/Details/277855007 xref: http://www.snomedbrowser.com/Codes/Details/277857004 xref: MA:0002650 xref: Urethral:sphincter is_a: UBERON:0003829 ! urethra muscle tissue [Term] id: UBERON:0004918 name: internal urethral sphincter namespace: uberon def: "A urethral sphincter muscle which constricts the internal urethral orifice. It is the junction of the urethra with the urinary bladder. The muscle is made of smooth muscle, so therefore it is under involuntary control. It is kept tonically contracted by the sympathetic nervous system and during micturition, is relaxed via the parasympathetic nervous system. This is the primary muscle for preventing the release of urine[WP]." [http://en.wikipedia.org/wiki/Internal_sphincter_muscle_of_urethra] synonym: "internal sphincter muscle of urethra" EXACT [] synonym: "internal sphincter of urethra" EXACT [] synonym: "internal urethral sphincter muscle" EXACT [] synonym: "musculus sphincter supracollicularis" EXACT LATIN [FMA:45769, FMA:TA] synonym: "musculus sphincter urethrae internus" EXACT LATIN [FMA:45769, FMA:TA] synonym: "musculus sphincter urethrae internus" RELATED LATIN [http://en.wikipedia.org/wiki/Internal_sphincter_muscle_of_urethra] synonym: "preprostatic sphincter" EXACT [FMA:45769] synonym: "sphincter urethrae internus" EXACT LATIN [FMA:45769, FMA:TA] synonym: "supracollicular sphincter" EXACT [FMA:45769] xref: FMA:45769 xref: http://en.wikipedia.org/wiki/Internal_sphincter_muscle_of_urethra xref: http://www.snomedbrowser.com/Codes/Details/277856008 is_a: UBERON:0004917 ! urethral sphincter property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/b/ba/Gray407.png xsd:anyURI [Term] id: UBERON:0004919 name: external urethral sphincter namespace: uberon def: "." [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra, http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra] synonym: "annulus urethralis" EXACT [] synonym: "external sphincter muscle of urethra" EXACT [] synonym: "external sphincter of urethra" EXACT [] synonym: "external urethral sphincter muscle" EXACT [] synonym: "m. urethralis" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/9879823] synonym: "musculus sphincter urethrae membranaceae" RELATED LATIN [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra] synonym: "urethralis" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/9879823, MA:0002401] synonym: "urethralis muscle" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/9879823] xref: EMAPA:37790 {source="MA:th"} xref: FMA:85274 xref: http://linkedlifedata.com/resource/umls/id/C1710586 xref: http://www.snomedbrowser.com/Codes/Details/19101001 xref: MA:0002401 xref: NCIT:C52561 xref: UMLS:C1710586 {source="ncithesaurus:Urethralis"} is_a: UBERON:0004917 ! urethral sphincter property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/7/70/Gray1166.png xsd:anyURI property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray1142.png xsd:anyURI [Term] id: UBERON:0004943 name: submucosa of urinary bladder namespace: uberon def: "The submucous layer of the wall of the urinary bladder." [BTO:0002117] synonym: "bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder" EXACT [OBOL:automatic] synonym: "submucous layer of urinary bladder" RELATED [BTO:0002117] synonym: "tela submucosa (vesica urinaria)" EXACT LATIN [FMA:15929, FMA:TA] synonym: "tela submucosa vesicae" EXACT LATIN [FMA:15929, FMA:TA] synonym: "tela submucosa vesicae urinariae" EXACT [BTO:0002117] synonym: "urinary bladder submucosa" EXACT [OBOL:automatic] xref: BTO:0002117 xref: EMAPA:32275 xref: FMA:15929 xref: http://www.snomedbrowser.com/Codes/Details/88384001 relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder [Term] id: UBERON:0004944 name: submucosa of trigone of urinary bladder namespace: uberon def: "A submucosa that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "deep trigone submucosa" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone submucosa" EXACT [OBOL:automatic] synonym: "submucosa of deep trigone" EXACT [OBOL:automatic] synonym: "submucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "submucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "submucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "submucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder submucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone submucosa" EXACT [OBOL:automatic] synonym: "vesical trigone submucosa" EXACT [OBOL:automatic] xref: EMAPA:32304 xref: FMA:17852 is_a: UBERON:0004943 ! submucosa of urinary bladder relationship: part_of UBERON:0001257 ! trigone of urinary bladder [Term] id: UBERON:0004945 name: submucosa of neck of urinary bladder namespace: uberon def: "A submucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck submucosa" EXACT [OBOL:automatic] synonym: "neck of bladder submucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "submucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck submucosa" EXACT [OBOL:automatic] synonym: "vesical neck submucosa" EXACT [OBOL:automatic] xref: EMAPA:32276 xref: FMA:17851 is_a: UBERON:0004943 ! submucosa of urinary bladder relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0004980 name: mucosa of ureter namespace: uberon def: "A mucosa that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of ureter" EXACT [OBOL:automatic] synonym: "mucosal layer of ureter" EXACT [FMA:15894] synonym: "mucous membrane of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of ureter" EXACT [OBOL:automatic] synonym: "tunica mucosa (ureter)" EXACT [FMA:15894] synonym: "tunica mucosa ureteris" EXACT LATIN [FMA:15894, FMA:TA] synonym: "ureter mucosa" EXACT [OBOL:automatic] synonym: "ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "ureter mucous membrane" EXACT [OBOL:automatic] synonym: "ureter organ mucosa" EXACT [OBOL:automatic] synonym: "ureteral mucosa" EXACT [FMA:15894] synonym: "ureteric mucosa" EXACT [FMA:15894] xref: FMA:15894 xref: galen:MucousMembraneOfUreter xref: http://www.snomedbrowser.com/Codes/Details/40476001 relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter [Term] id: UBERON:0005004 name: mucosa of right ureter namespace: uberon def: "A mucosa that is part of a right ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of right ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of right ureter" EXACT [OBOL:automatic] synonym: "right ureter mucosa" EXACT [OBOL:automatic] synonym: "right ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "right ureter mucous membrane" EXACT [OBOL:automatic] synonym: "right ureter organ mucosa" EXACT [OBOL:automatic] synonym: "right ureteral mucosa" EXACT [FMA:17806] xref: FMA:17806 is_a: UBERON:0004980 ! mucosa of ureter relationship: part_of UBERON:0001222 ! right ureter [Term] id: UBERON:0005005 name: mucosa of left ureter namespace: uberon def: "A mucosa that is part of a left ureter [Automatically generated definition]." [OBOL:automatic] synonym: "left ureter mucosa" EXACT [OBOL:automatic] synonym: "left ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "left ureter mucous membrane" EXACT [OBOL:automatic] synonym: "left ureter organ mucosa" EXACT [OBOL:automatic] synonym: "left ureteral mucosa" EXACT [FMA:17807] synonym: "mucosa of organ of left ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of left ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of left ureter" EXACT [OBOL:automatic] xref: FMA:17807 is_a: UBERON:0004980 ! mucosa of ureter relationship: part_of UBERON:0001223 ! left ureter [Term] id: UBERON:0005006 name: mucosa of renal pelvis namespace: uberon def: "A mucosa that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "kidney pelvis mucosa" EXACT [OBOL:automatic] synonym: "kidney pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "kidney pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "kidney pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucosa of organ of renal pelvis" EXACT [OBOL:automatic] synonym: "mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucous membrane of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of renal pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of renal pelvis" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucous membrane" EXACT [OBOL:automatic] synonym: "pelvis of ureter organ mucosa" EXACT [OBOL:automatic] synonym: "renal pelvic mucosa" EXACT [FMA:17931] synonym: "renal pelvis mucosa" EXACT [OBOL:automatic] synonym: "renal pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "renal pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "renal pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa pelvis renalis" EXACT LATIN [FMA:17931, FMA:TA] xref: FMA:17931 xref: http://www.snomedbrowser.com/Codes/Details/243482002 relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0005007 name: mucosa of major calyx namespace: uberon def: "A mucosa that is part of a major calyx [Automatically generated definition]." [OBOL:automatic] synonym: "major calix mucosa" EXACT [OBOL:automatic] synonym: "major calix mucosa of organ" EXACT [OBOL:automatic] synonym: "major calix mucous membrane" EXACT [OBOL:automatic] synonym: "major calix organ mucosa" EXACT [OBOL:automatic] synonym: "major calyx mucosa" EXACT [OBOL:automatic] synonym: "major calyx mucosa of organ" EXACT [OBOL:automatic] synonym: "major calyx mucous membrane" EXACT [OBOL:automatic] synonym: "major calyx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of major calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of major calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of major calyx" EXACT [OBOL:automatic] synonym: "mucous membrane of major calix" EXACT [OBOL:automatic] synonym: "mucous membrane of major calyx" EXACT [OBOL:automatic] synonym: "organ mucosa of major calix" EXACT [OBOL:automatic] synonym: "organ mucosa of major calyx" EXACT [OBOL:automatic] xref: FMA:17934 is_a: UBERON:0005006 ! mucosa of renal pelvis relationship: part_of UBERON:0001226 ! major calyx [Term] id: UBERON:0005008 name: mucosa of minor calyx namespace: uberon def: "A mucosa that is part of a minor calyx [Automatically generated definition]." [OBOL:automatic] synonym: "minor calix mucosa" EXACT [OBOL:automatic] synonym: "minor calix mucosa of organ" EXACT [OBOL:automatic] synonym: "minor calix mucous membrane" EXACT [OBOL:automatic] synonym: "minor calix organ mucosa" EXACT [OBOL:automatic] synonym: "minor calyx mucosa" EXACT [OBOL:automatic] synonym: "minor calyx mucosa of organ" EXACT [OBOL:automatic] synonym: "minor calyx mucous membrane" EXACT [OBOL:automatic] synonym: "minor calyx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of minor calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of minor calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of minor calyx" EXACT [OBOL:automatic] synonym: "mucous membrane of minor calix" EXACT [OBOL:automatic] synonym: "mucous membrane of minor calyx" EXACT [OBOL:automatic] synonym: "organ mucosa of minor calix" EXACT [OBOL:automatic] synonym: "organ mucosa of minor calyx" EXACT [OBOL:automatic] xref: FMA:17937 is_a: UBERON:0005006 ! mucosa of renal pelvis relationship: part_of UBERON:0001227 ! minor calyx [Term] id: UBERON:0005009 name: mucosa of trigone of urinary bladder namespace: uberon def: "A mucosa that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "deep trigone mucosa" EXACT [OBOL:automatic] synonym: "deep trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "deep trigone mucous membrane" EXACT [OBOL:automatic] synonym: "deep trigone organ mucosa" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone mucosa" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone mucous membrane" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of deep trigone" EXACT [OBOL:automatic] synonym: "mucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of deep trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of vesical trigone" EXACT [OBOL:automatic] synonym: "mucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of deep trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of vesical trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of deep trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder mucosa" EXACT [OBOL:automatic] synonym: "trigone of bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "trigone of bladder mucous membrane" EXACT [OBOL:automatic] synonym: "trigone of bladder organ mucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucous membrane" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder organ mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucous membrane" EXACT [OBOL:automatic] synonym: "urinary bladder trigone organ mucosa" EXACT [OBOL:automatic] synonym: "vesical trigone mucosa" EXACT [OBOL:automatic] synonym: "vesical trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "vesical trigone mucous membrane" EXACT [OBOL:automatic] synonym: "vesical trigone organ mucosa" EXACT [OBOL:automatic] xref: FMA:17847 is_a: UBERON:0001259 ! mucosa of urinary bladder relationship: part_of UBERON:0001257 ! trigone of urinary bladder [Term] id: UBERON:0005010 name: mucosa of neck of urinary bladder namespace: uberon def: "A mucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck mucosa" EXACT [OBOL:automatic] synonym: "bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "bladder neck organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of vesical neck" EXACT [OBOL:automatic] synonym: "mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of bladder organ mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of urinary bladder organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck mucosa" EXACT [OBOL:automatic] synonym: "vesical neck mucosa of organ" EXACT [OBOL:automatic] synonym: "vesical neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck organ mucosa" EXACT [OBOL:automatic] xref: FMA:17846 is_a: UBERON:0001259 ! mucosa of urinary bladder relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0005013 name: mucosa of male urethra namespace: uberon def: "A mucosa that is part of a male urethra [Automatically generated definition]." [OBOL:automatic] synonym: "male urethra mucosa" EXACT [OBOL:automatic] synonym: "male urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "male urethra mucous membrane" EXACT [OBOL:automatic] synonym: "male urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of male urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of male urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of male urethra" EXACT [OBOL:automatic] xref: FMA:239937 is_a: UBERON:0012299 ! mucosa of urethra relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0005014 name: mucosa of female urethra namespace: uberon def: "A mucosa that is part of a female urethra [Automatically generated definition]." [OBOL:automatic] synonym: "female urethra mucosa" EXACT [OBOL:automatic] synonym: "female urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "female urethra mucous membrane" EXACT [OBOL:automatic] synonym: "female urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of female urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of female urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of female urethra" EXACT [OBOL:automatic] xref: FMA:239940 is_a: UBERON:0012299 ! mucosa of urethra relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0005015 name: mucosa of prostatic urethra namespace: uberon def: "A mucosa that is part of a prostatic urethra [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of prostatic urethra" EXACT [OBOL:automatic] synonym: "mucosa of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of prostatic urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of prostatic urethra" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucosa" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "prostatic part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethra mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "prostatic urethra mucous membrane" EXACT [OBOL:automatic] synonym: "prostatic urethra organ mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethral mucosa" EXACT [FMA:77079] synonym: "tunica mucosa urethrae prosticae" EXACT LATIN [FMA:77079, FMA:TA] xref: FMA:77079 is_a: UBERON:0005013 ! mucosa of male urethra relationship: part_of UBERON:0001335 ! prostatic urethra [Term] id: UBERON:0005016 name: mucosa of intermediate urethra namespace: uberon def: "A mucosa that is part of a membranous urethra [Automatically generated definition]." [OBOL:automatic] synonym: "intermediate part of urethra mucosa" EXACT [OBOL:automatic] synonym: "intermediate part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "intermediate part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "intermediate part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethra mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "intermediate urethra mucous membrane" EXACT [OBOL:automatic] synonym: "intermediate urethra organ mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethral mucosa" EXACT [FMA:77085] synonym: "membranous part of urethra mucosa" EXACT [OBOL:automatic] synonym: "membranous part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "membranous part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "membranous part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "membranous urethra mucosa" EXACT [OBOL:automatic] synonym: "membranous urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "membranous urethra mucous membrane" EXACT [OBOL:automatic] synonym: "membranous urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of membranous urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of intermediate urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of membranous urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "mucosa of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "mucous membrane of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of intermediate urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of membranous urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "organ mucosa of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of intermediate urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of membranous part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of membranous urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucosa" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucosa of organ" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucous membrane" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa urethrae intermediae" EXACT LATIN [FMA:77085, FMA:TA] xref: FMA:77085 xref: galen:MucousMembraneOfUrethra xref: http://www.snomedbrowser.com/Codes/Details/362229009 is_a: UBERON:0012299 ! mucosa of urethra relationship: part_of UBERON:0001336 ! membranous urethra of male or female [Term] id: UBERON:0005080 name: metanephric ureteric bud namespace: uberon def: "The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]." [GO:0035502] is_a: UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005081 name: ureter ureteric bud namespace: uberon def: "The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]." [GO:0035503] is_a: UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005096 name: descending thin limb namespace: uberon alt_id: UBERON:0005165 def: "The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle[GO]." [GO:0072022, http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] subset: uberon_slim synonym: "descending limb of Henle's loop" RELATED [http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] synonym: "descending limb of loop of Henle" RELATED [http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] synonym: "descending thin limb of loop of Henle" EXACT [] synonym: "loop of Henle descending thin limb" EXACT [] synonym: "loop of Henle thin descending limb" EXACT [MA:0002625] synonym: "pars descendens (tubulus attenuatus)" EXACT [FMA:17719] synonym: "thin descending limb" EXACT [] synonym: "thin descending limb of loop of Henle" RELATED [http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] synonym: "thin descending limb of the loop of Henle" RELATED [http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] synonym: "thin descending loop of Henle" RELATED [http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle] xref: EMAPA:35514 xref: FMA:17719 xref: http://en.wikipedia.org/wiki/Descending_limb_of_loop_of_Henle xref: MA:0002625 relationship: part_of UBERON:0004136 ! intermediate tubule property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0005097 name: renal connecting tubule namespace: uberon def: "The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]." [GO:0072027, http://en.wikipedia.org/wiki/Connecting_tubule] synonym: "connecting tubule" EXACT [MA:0002610] synonym: "kidney connecting tubule" EXACT [MA:0002610] synonym: "tubulus renalis arcuatus" RELATED LATIN [http://en.wikipedia.org/wiki/Connecting_tubule] xref: BTO:0004539 xref: Connecting:tubule xref: EMAPA:27758 xref: EMAPA:27790 xref: EMAPA:28011 xref: MA:0002610 is_a: UBERON:0007685 ! region of nephron tubule property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0005099 name: short descending thin limb namespace: uberon def: "The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology[GO]." [GO:0072063] is_a: UBERON:0004211 ! nephron epithelium property_value: IAO:0000116 "TODO - epithelium types" xsd:string [Term] id: UBERON:0005100 name: long descending thin limb namespace: uberon def: "The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]." [GO:0072064] is_a: UBERON:0004211 ! nephron epithelium [Term] id: UBERON:0005101 name: early distal convoluted tubule namespace: uberon def: "The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO]." [GO:0072067] xref: EMAPA:28393 is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001292 ! distal convoluted tubule [Term] id: UBERON:0005102 name: late distal convoluted tubule namespace: uberon def: "The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]." [GO:0072068] xref: EMAPA:28393 is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001292 ! distal convoluted tubule property_value: IAO:0000116 "TODO - CL" xsd:string [Term] id: UBERON:0005103 name: mesonephric epithelium namespace: uberon def: "An epithelium that is part of a mesonephros [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0004819 ! kidney epithelium relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005104 name: anterior mesonephric tubule namespace: uberon def: "." [GO:0072165] synonym: "cranial mesonephric tubule" EXACT [EMAPA:30562] xref: EMAPA:30562 is_a: UBERON:0000083 ! mesonephric tubule [Term] id: UBERON:0005105 name: posterior mesonephric tubule namespace: uberon def: "." [GO:0072166] synonym: "caudal mesonephric tubule" EXACT [EMAPA:30574] xref: EMAPA:30571 is_a: UBERON:0000083 ! mesonephric tubule [Term] id: UBERON:0005106 name: metanephric tubule namespace: uberon def: "A metanephric tubule is an epithelial tube that is part of the metanephros[GO]." [GO:0072173] xref: VHOG:0001526 is_a: UBERON:0005108 ! metanephric epithelium is_a: UBERON:0006555 ! excretory tube property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001526", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543"} [Term] id: UBERON:0005108 name: metanephric epithelium namespace: uberon def: "An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]." [GO:0072207] is_a: UBERON:0004819 ! kidney epithelium relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005109 name: metanephric smooth muscle tissue namespace: uberon def: "Any smooth muscle tissue that is part of a metanephros." [GO:0072208, https://orcid.org/0000-0002-6601-2165] relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005110 name: metanephric nephron namespace: uberon alt_id: UBERON:0005142 def: "A metanephric nephron is the functional unit of the metanephros[GO]." [GO:0072273] xref: VHOG:0000719 is_a: UBERON:0001285 ! nephron relationship: part_of UBERON:0000081 ! metanephros property_value: UBPROP:0000003 "The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000719", ontology="VHOG", source="http://bgee.unil.ch/", source="DOI:10.1093/icb/34.4.542 Ruppert EE, Evolutionary Origin of the Vertebrate Nephron. Integrative and Comparative Biology (1994)"} [Term] id: UBERON:0005111 name: metanephric pyramid namespace: uberon def: "Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts[GO]." [GO:0072211] is_a: UBERON:0004200 ! kidney pyramid relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005114 name: metanephric ascending thin limb namespace: uberon def: "The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent[GO]." [GO:0072218] is_a: UBERON:0004193 ! loop of Henle ascending limb thin segment is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0005129 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric distal tubule [Term] id: UBERON:0005115 name: metanephric cortical collecting duct namespace: uberon def: "The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]." [GO:0072219] is_a: UBERON:0004203 ! cortical collecting duct relationship: part_of UBERON:0004737 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric collecting duct relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0005116 name: metanephric descending thin limb namespace: uberon def: "It extends to the tip of the metanephric loop of Henle[GO]." [GO:0072220] is_a: UBERON:0005096 ! descending thin limb relationship: part_of UBERON:0005130 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric loop of Henle [Term] id: UBERON:0005117 name: metanephric distal convoluted tubule namespace: uberon def: "The metanephric distal convoluted tubule is a portion of the metanephric nephron tubule that connects the metanephric loop of Henle to the collecting duct[GO]." [GO:0072221] xref: VHOG:0001569 is_a: UBERON:0001292 ! distal convoluted tubule is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0005118 name: metanephric early distal convoluted tubule namespace: uberon def: "The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive[GO]." [GO:0072222] is_a: UBERON:0005101 ! early distal convoluted tubule is_a: UBERON:0005134 ! metanephric nephron epithelium relationship: part_of UBERON:0005117 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric distal convoluted tubule relationship: part_of UBERON:0005129 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric distal tubule [Term] id: UBERON:0005119 name: metanephric glomerular mesangium namespace: uberon def: "The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus[GO]." [GO:0072223] is_a: UBERON:0002320 ! glomerular mesangium relationship: part_of UBERON:0005133 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric glomerulus vasculature [Term] id: UBERON:0005120 name: metanephric late distal convoluted tubule namespace: uberon def: "The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]." [GO:0072225] is_a: UBERON:0005102 ! late distal convoluted tubule is_a: UBERON:0005134 ! metanephric nephron epithelium relationship: part_of UBERON:0005117 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric distal convoluted tubule relationship: part_of UBERON:0005129 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric distal tubule [Term] id: UBERON:0005121 name: metanephric long descending thin limb bend namespace: uberon def: "The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros[GO]." [GO:0072226] is_a: UBERON:0004206 ! long descending thin limb bend relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005122 name: metanephric macula densa namespace: uberon def: "The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO]." [GO:0072227] is_a: UBERON:0002335 ! macula densa is_a: UBERON:0005134 ! metanephric nephron epithelium relationship: part_of UBERON:0004738 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric juxtaglomerular apparatus [Term] id: UBERON:0005123 name: metanephric prebend segment namespace: uberon def: "The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability[GO]." [GO:0072228] is_a: UBERON:0004207 ! prebend segment of loop of Henle relationship: part_of UBERON:0005116 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric descending thin limb [Term] id: UBERON:0005124 name: metanephric proximal convoluted tubule namespace: uberon def: "The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule[GO]." [GO:0072229] xref: VHOG:0001570 is_a: UBERON:0001287 ! proximal convoluted tubule is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0005125 name: metanephric proximal straight tubule namespace: uberon def: "The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule[GO]." [GO:0072230] is_a: UBERON:0001290 ! proximal straight tubule is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0005151 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric proximal tubule property_value: IAO:0000116 "TODO - place mammalian xrefs here rather than at parent" xsd:string [Term] id: UBERON:0005126 name: metanephric S1 namespace: uberon def: "The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]." [GO:0072231] is_a: UBERON:0004196 ! proximal convoluted tubule segment 1 relationship: part_of UBERON:0005124 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric proximal convoluted tubule [Term] id: UBERON:0005127 name: metanephric thick ascending limb namespace: uberon def: "At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO]." [GO:0072233] is_a: UBERON:0001291 ! thick ascending limb of loop of Henle is_a: UBERON:0005146 ! metanephric nephron tubule [Term] id: UBERON:0005129 name: metanephric distal tubule namespace: uberon alt_id: UBERON:0005150 def: "The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule[GO]." [GO:0072235] is_a: UBERON:0004135 ! distal tubule is_a: UBERON:0005146 ! metanephric nephron tubule [Term] id: UBERON:0005130 name: metanephric loop of Henle namespace: uberon def: "The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros[GO]." [GO:0072236] is_a: UBERON:0001288 ! loop of Henle is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0004136 ! intermediate tubule [Term] id: UBERON:0005132 name: metanephric long nephron namespace: uberon def: "Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros[GO]." [GO:0072238] is_a: UBERON:0004194 ! long nephron is_a: UBERON:0005110 ! metanephric nephron [Term] id: UBERON:0005133 name: metanephric glomerulus vasculature namespace: uberon alt_id: UBERON:0005143 def: "The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus[GO]." [GO:0072239] is_a: UBERON:0004190 ! renal glomerulus vasculature relationship: part_of UBERON:0004736 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric glomerulus [Term] id: UBERON:0005134 name: metanephric nephron epithelium namespace: uberon def: "The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]." [GO:0072243] is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0005108 ! metanephric epithelium relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0005135 name: metanephric glomerular epithelium namespace: uberon def: "A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros[GO]." [GO:0072244] is_a: UBERON:0004188 ! glomerular epithelium is_a: UBERON:0005134 ! metanephric nephron epithelium relationship: part_of UBERON:0004736 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric glomerulus [Term] id: UBERON:0005136 name: metanephric glomerular endothelium namespace: uberon def: "The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros[GO]." [GO:0072264] is_a: UBERON:0004189 ! glomerular endothelium is_a: UBERON:0005135 ! metanephric glomerular epithelium relationship: part_of UBERON:0005133 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric glomerulus vasculature [Term] id: UBERON:0005137 name: metanephric capsule namespace: uberon alt_id: UBERON:0005112 def: "The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]." [GO:0072213] is_a: UBERON:0002015 ! kidney capsule relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005139 name: metanephric long descending thin limb namespace: uberon is_a: UBERON:0005100 ! long descending thin limb is_a: UBERON:0005134 ! metanephric nephron epithelium [Term] id: UBERON:0005140 name: metanephric short nephron namespace: uberon def: "Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb[GO]." [GO:0072270] is_a: UBERON:0004195 ! short nephron is_a: UBERON:0005110 ! metanephric nephron [Term] id: UBERON:0005141 name: metanephric short descending thin limb namespace: uberon def: "The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology[GO]." [GO:0072271] is_a: UBERON:0005099 ! short descending thin limb is_a: UBERON:0005134 ! metanephric nephron epithelium [Term] id: UBERON:0005144 name: metanephric glomerular capillary namespace: uberon def: "This process pertains to the initial formation of a structure from unspecified parts[GO]." [GO:0072277] is_a: UBERON:0004212 ! glomerular capillary relationship: part_of UBERON:0004736 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric glomerulus relationship: part_of UBERON:0005110 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0005145 name: metanephric comma-shaped body namespace: uberon def: "The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]." [GO:0072278] is_a: UBERON:0004198 ! comma-shaped body relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005146 name: metanephric nephron tubule namespace: uberon alt_id: UBERON:0005128 alt_id: UBERON:0005152 def: "A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]." [GO:0072282] is_a: UBERON:0001231 ! nephron tubule is_a: UBERON:0005106 ! metanephric tubule is_a: UBERON:0005134 ! metanephric nephron epithelium [Term] id: UBERON:0005147 name: metanephric renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0072283] synonym: "metanephric vesicle" EXACT [] xref: EHDAA2:0001245 xref: EHDAA:9346 xref: EMAPA:27678 is_a: UBERON:0005108 ! metanephric epithelium [Term] id: UBERON:0005148 name: metanephric S-shaped body namespace: uberon def: "The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]." [GO:0072284] is_a: UBERON:0004199 ! S-shaped body relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0005149 name: metanephric connecting tubule namespace: uberon def: "The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros[GO]." [GO:0072286] is_a: UBERON:0005097 ! renal connecting tubule is_a: UBERON:0005146 ! metanephric nephron tubule [Term] id: UBERON:0005151 name: metanephric proximal tubule namespace: uberon alt_id: UBERON:0005131 def: "The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology[GO]." [GO:0072288] is_a: UBERON:0004134 ! proximal tubule is_a: UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0005164 name: ascending limb of loop of Henle namespace: uberon def: "The distal part of the loop of Henle that is impermeable to water and actively pumps sodium out of the filtrate to generate the hypertonic interstitium that drives countercurrent exchange; it consists of an initial very thin segment lined by simple squamous epithelium followed by a distal thick segment lined by simple cuboidal epithelium[MP]." [http://en.wikipedia.org/wiki/Ascending_limb_of_loop_of_Henle, MP:0011342] subset: pheno_slim subset: uberon_slim synonym: "ascending limb" BROAD [] synonym: "ascending limb of Henle's loop" EXACT [] synonym: "distal straight tubule" RELATED [] synonym: "loop of Henle ascending limb" EXACT [MP:0011342] xref: EMAPA:35510 xref: FMA:17717 xref: http://en.wikipedia.org/wiki/Ascending_limb_of_loop_of_Henle xref: http://linkedlifedata.com/resource/umls/id/C0227658 xref: http://www.snomedbrowser.com/Codes/Details/245434005 xref: MA:0001676 xref: NCIT:C32154 xref: UMLS:C0227658 {source="ncithesaurus:Ascending_Limb_of_the_Henle_s_Loop"} is_a: UBERON:0004135 ! distal tubule relationship: part_of UBERON:0001288 ! loop of Henle property_value: IAO:0000116 "TODO - thick/thin check. Also relationship to distal tubule. We need a home for MA:0002634-renal straight tubule" xsd:string [Term] id: UBERON:0005167 name: papillary duct namespace: uberon def: "The terminal portions of the medullary collecting ducts are the papillary ducts, which end at the renal papilla and empty into a minor calyx." [http://encyclopedia.thefreedictionary.com/] subset: pheno_slim synonym: "Bellini's duct" RELATED [MP:0011331] synonym: "duct of Bellini" RELATED [] synonym: "papillary duct" EXACT [] synonym: "papillary duct of kidney" EXACT [] synonym: "renal papillary duct" EXACT [] xref: BTO:0004540 xref: EMAPA:35655 xref: http://en.wikipedia.org/wiki/Duct_of_Bellini xref: http://www.snomedbrowser.com/Codes/Details/110623009 xref: MA:0001646 is_a: UBERON:0001232 ! collecting duct of renal tubule [Term] id: UBERON:0005168 name: renal interlobular vein namespace: uberon def: "Any of the veins that parallel the interlobular arteries, receiving blood from the peritubular capillary plexus and empty into the arcuate veins" [ISBN:0-683-40008-8, MP:0011326] subset: pheno_slim synonym: "interlobular vein" EXACT [MA:0002594] synonym: "interlobular veins of kidney" RELATED [FMA:71634] synonym: "set of interlobular veins of kidney" RELATED [FMA:71634] synonym: "venae interlobulares renis" EXACT LATIN [FMA:71634, FMA:TA] synonym: "venae interlobulares renis" RELATED LATIN [http://en.wikipedia.org/wiki/Interlobular_veins] xref: EMAPA:28218 xref: FMA:71634 xref: Interlobular:veins xref: MA:0002594 is_a: UBERON:0014401 ! renal venous blood vessel relationship: part_of UBERON:0001225 ! cortex of kidney property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png xsd:anyURI [Term] id: UBERON:0005185 name: renal medulla collecting duct namespace: uberon def: "The portion of the collecting duct that resides in the renal medulla" [http://orcid.org/0000-0002-6601-2165] synonym: "kidney medulla collecting duct" EXACT [MA:0002935] synonym: "medullary collecting duct" EXACT [EMAPA:28061] xref: BTO:0004536 xref: EMAPA:28061 xref: EMAPA:35459 xref: MA:0002935 relationship: part_of UBERON:0000362 ! renal medulla relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: UBERON:0005202 name: distal straight tubule macula densa namespace: uberon def: "A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:28399 xref: MA:0002604 is_a: UBERON:0002335 ! macula densa relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006853 {source="MA"} ! renal cortex tubule property_value: IAO:0000116 "TODO - unify terminology - check DST = TAL? Note EMAPA class appears to refer to this segment" xsd:string [Term] id: UBERON:0005211 name: renal medulla interstitium namespace: uberon def: "tissue surrounding the loop of Henle in the renal medulla." [http://en.wikipedia.org/wiki/Bone_marrow_of_ovaryry_interstitium] synonym: "kidney medulla interstitium" EXACT [MA:0002619] synonym: "medullary interstitium" NARROW [http://en.wikipedia.org/wiki/Medullary_interstitium] synonym: "medullary stroma" RELATED [EMAPA:18326] synonym: "renal medullary interstitial tissue" EXACT [] synonym: "renal medullary interstitium" EXACT [EMAPA:18326] xref: EMAPA:18326 xref: http://en.wikipedia.org/wiki/Bone_marrow_of_ovaryry_interstitium xref: http://www.snomedbrowser.com/Codes/Details/245693005 xref: MA:0002619 is_a: UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0000362 ! renal medulla property_value: UBPROP:0000009 "It functions in renal water reabsorption by building up a high hypertonicity, which draws water out of the thin descending limb of the loop of Henle and the collecting duct system. This hypertonicity, in turn, is created by an efflux of urea from the inner medullary collecting duct." xsd:string [Term] id: UBERON:0005213 name: outer renal medulla interstitium namespace: uberon def: "A portion of interstitial tissue that is part of a outer medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "kidney outer medulla interstitium" EXACT [MA:0002621] synonym: "outer medullary interstitium" EXACT [EMAPA:28337] xref: EMAPA:28337 xref: MA:0002621 is_a: UBERON:0005211 ! renal medulla interstitium relationship: part_of UBERON:0001293 {source="MA"} ! outer medulla of kidney [Term] id: UBERON:0005214 name: inner renal medulla interstitium namespace: uberon def: "A portion of interstitial tissue that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "inner medullary interstitium" EXACT [EMAPA:28364] synonym: "kidney inner medulla interstitium" EXACT [MA:0002620] synonym: "papillary interstitium" RELATED [EMAPA:28364] xref: EMAPA:28364 xref: MA:0002620 is_a: UBERON:0005211 ! renal medulla interstitium relationship: part_of UBERON:0001294 {source="MA"} ! inner medulla of kidney [Term] id: UBERON:0005215 name: kidney interstitium namespace: uberon def: "The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes." [http://orcid.org/0000-0002-6601-2165, http://www.ncbi.nlm.nih.gov/pubmed/18575881, https://doi.org/10.1038/ki.1991.49] subset: pheno_slim synonym: "interstitial tissue of kidney" EXACT [] synonym: "kidney interstitium group" RELATED [EMAPA:28518] synonym: "renal interstitial tissue" EXACT [] synonym: "renal interstitium" EXACT [FMA:70983] synonym: "renal stroma" EXACT [FMA:70983] synonym: "stroma of kidney" EXACT [FMA:70983] xref: EMAPA:28518 xref: FMA:70983 xref: http://www.snomedbrowser.com/Codes/Details/362210003 xref: MA:0002616 xref: NCIT:C33459 relationship: part_of UBERON:0002113 ! kidney property_value: IAO:0000116 "See https://sourceforge.net/p/geneontology/ontology-requests/10941/" xsd:string property_value: UBPROP:0000009 "The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment." xsd:string property_value: UBPROP:0000010 "The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue." xsd:string [Term] id: UBERON:0005249 name: metanephric renal pelvis namespace: uberon def: "A renal pelvis that is part of a metanephros." [OBOL:automatic] synonym: "metanephros pelvis" EXACT [VHOG:0000945] xref: VHOG:0000945 is_a: UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0000081 ! metanephros property_value: UBPROP:0000003 "The ureteric bud itself forms the collecting tubules and the ureter that drain the adult kidney. This type of kidney, called the metanephros, occurs in all adult amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000945", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639"} [Term] id: UBERON:0005268 name: renal cortex artery namespace: uberon def: "An artery that supplies the renal cortex." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "kidney cortex artery" EXACT [MP:0011314] synonym: "renal cortex arterial system" RELATED [MA:0002582] synonym: "renal cortex artery" EXACT [MA:0002582] xref: EMAPA:28147 xref: MA:0002582 is_a: UBERON:0003644 ! kidney arterial blood vessel relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0005269 name: renal cortex vein namespace: uberon def: "Artery that receives blood from the renal cortex[MP, modified]" [MGI:csmith] subset: pheno_slim synonym: "kidney cortex vein" RELATED [MP:0011322] synonym: "renal cortex venous system" RELATED [MA:0002592] xref: EMAPA:28152 xref: MA:0002592 is_a: UBERON:0014401 ! renal venous blood vessel relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0005270 name: renal cortex interstitium namespace: uberon def: "A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells." [http://www.ncbi.nlm.nih.gov/pubmed/18575881] synonym: "cortical stroma" RELATED [EMAPA:28136] synonym: "kidney cortex interstitium" EXACT [MA:0002608] synonym: "renal cortical interstitial tissue" EXACT [] xref: EMAPA:28136 xref: http://www.snomedbrowser.com/Codes/Details/243707006 xref: MA:0002608 xref: Medullary:interstitium is_a: UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney property_value: UBPROP:0000010 "In the renal cortex, interstitial fibroblasts produce erythropoietin and are distinguished from other interstitial cells by their prominent F-actin cytoskeleton, abundance of rough endoplasmic reticulum, and by ecto-5'-nucleotidase expression in their plasma membrane. The resident dendritic cells belong to the mononuclear phagocyte system and fulfil a sentinel function. They are characterized by their expression of MHC class II and CD11c." xsd:string {source="http://www.ncbi.nlm.nih.gov/pubmed/18575881"} [Term] id: UBERON:0005271 name: juxtamedullary cortex namespace: uberon def: "The part of the renal cortex nearest to the medulla." [http://medical-dictionary.thefreedictionary.com/juxtamedullary+cortex] synonym: "inner cortex of kidney" EXACT [FMA:74288] synonym: "inner renal cortex" EXACT [KUPO:0001008] synonym: "juxtamedullary cortex of kidney" EXACT [FMA:74288] xref: EMAPA:37623 {source="MA:th"} xref: FMA:74288 xref: KUPO:0001008 xref: MA:0001648 relationship: part_of UBERON:0001225 {source="FMA", source="KUPO"} ! cortex of kidney [Term] id: UBERON:0005272 name: peritubular capillary namespace: uberon def: "the tiny blood vessels that receive blood from the efferent arterioles of the glomerulus, and interact with superficial cortical nephrons allowing reabsorption and secretion between blood and the inner lumen of the nephron; peritubular capillaries are situated around the tubule and are at low pressure" [MGI:csmith, MP:0011321] subset: pheno_slim xref: EMAPA:36558 xref: MA:0002588 xref: Peritubular:capillaries is_a: UBERON:0003527 ! kidney capillary [Term] id: UBERON:0005308 name: nephrostome namespace: uberon def: "The nephrostome is the opening of the pronephros into the body cavity[GO]." [GO:0039018] xref: AAO:0011069 xref: http://en.wikipedia.org/wiki/Nephrostome xref: XAO:0000062 relationship: part_of UBERON:0002120 ! pronephros [Term] id: UBERON:0005309 name: pronephric nephron namespace: uberon def: "A pronephric nephron is the functional unit of the pronephros[GO]." [GO:0039019] xref: AAO:0011091 xref: XAO:0000285 is_a: UBERON:0001285 ! nephron relationship: part_of UBERON:0002120 ! pronephros property_value: UBPROP:0000001 "The structure that is the basic functional unit of the pronephros.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011091", ontology="AAO", source="UBERON:0005309"} [Term] id: UBERON:0005310 name: pronephric nephron tubule namespace: uberon def: "The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]." [GO:0039020] synonym: "ciliated neck segment" RELATED [ZFA:0001558] synonym: "pronephric tubule" EXACT [ZFA:0001558] xref: TAO:0001558 xref: XAO:0004105 xref: ZFA:0001558 is_a: UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0005309 {source="GO"} ! pronephric nephron property_value: RO:0002174 NCBITaxon:32524 {source="ISBN:0073040584"} property_value: UBPROP:0000001 "Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001558", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005312 name: primary ureteric bud namespace: uberon def: "." [GO:0060682] is_a: UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005319 name: mesonephric collecting duct namespace: uberon def: "The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]." [GO:0061211] xref: AAO:0010390 xref: XAO:0000151 is_a: UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron [Term] id: UBERON:0005320 name: mesonephric juxtaglomerular apparatus namespace: uberon def: "The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]." [GO:0061212] is_a: UBERON:0002303 ! juxtaglomerular apparatus relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005321 name: mesonephric smooth muscle tissue namespace: uberon def: "." [GO:0061214] relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005322 name: mesonephric nephron namespace: uberon def: "A nephron that is part of a mesonephros." [http://orcid.org/0000-0002-6601-2165] synonym: "nephron of mesonephros" EXACT [] synonym: "stage IV nephron" RELATED [ZFA:0005592] xref: AAO:0010387 xref: XAO:0000292 xref: ZFA:0005592 is_a: UBERON:0001285 ! nephron relationship: part_of UBERON:0000080 ! mesonephros property_value: UBPROP:0000001 "The structure that is the basic functional unit of the kidney.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010387", ontology="AAO", source="http://www.ncbi.nlm.nih.gov/pubmed/9268568"} [Term] id: UBERON:0005323 name: mesonephric mesenchyme namespace: uberon def: "Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]." [GO:0061219] subset: pheno_slim xref: AAO:0011062 xref: EHDAA2:0001132 xref: EMAPA:16745 xref: XAO:0000291 relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005324 name: mesonephric macula densa namespace: uberon def: "The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus[GO]." [GO:0061220] is_a: UBERON:0002335 ! macula densa is_a: UBERON:0005330 ! mesonephric nephron epithelium relationship: part_of UBERON:0005320 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric juxtaglomerular apparatus [Term] id: UBERON:0005325 name: mesonephric glomerulus namespace: uberon def: "The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros[GO]." [GO:0061224] synonym: "glomerulus" BROAD SENSU [AAO:0010388] xref: AAO:0010388 xref: EMAPA:30568 xref: http://www.snomedbrowser.com/Codes/Details/362217000 xref: VHOG:0001238 xref: XAO:0000146 is_a: UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0000080 ! mesonephros property_value: UBPROP:0000001 "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010388", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In animals in which the mesonephros is the terminal kidney, such as amphibians and fish, the final organ is very complex, containing a large number of nephrons, most of which have an internal glomerulus.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001238", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0127224411 Vize PD, Woolf AS, Bard JBL, The kidney: From normal development to congenital disease (2003) p.3"} property_value: UBPROP:0000012 "XAO/AAO class belongs here, as it refers to mesonephric structure" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0005326 name: mesonephric glomerulus vasculature namespace: uberon def: "The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus[GO]." [GO:0061231] is_a: UBERON:0004190 ! renal glomerulus vasculature relationship: part_of UBERON:0005325 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric glomerulus [Term] id: UBERON:0005327 name: mesonephric glomerular epithelium namespace: uberon def: "A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros[GO]." [GO:0061232] is_a: UBERON:0004188 ! glomerular epithelium is_a: UBERON:0005330 ! mesonephric nephron epithelium relationship: part_of UBERON:0005325 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric glomerulus [Term] id: UBERON:0005328 name: mesonephric comma-shaped body namespace: uberon def: "The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]." [GO:0061236] is_a: UBERON:0004198 ! comma-shaped body relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005329 name: mesonephric nephron tubule namespace: uberon def: "A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros[GO]." [GO:0061240] synonym: "mesonephric renal tubule" EXACT [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0001231 ! nephron tubule is_a: UBERON:0005330 ! mesonephric nephron epithelium [Term] id: UBERON:0005330 name: mesonephric nephron epithelium namespace: uberon def: "The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]." [GO:0061241] is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0005103 ! mesonephric epithelium relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron [Term] id: UBERON:0005331 name: mesonephric renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0061243] synonym: "mesonephric vesicle" EXACT [] xref: http://www.snomedbrowser.com/Codes/Details/361407006 xref: ZFA:0005586 is_a: UBERON:0005103 ! mesonephric epithelium [Term] id: UBERON:0005332 name: mesonephric S-shaped body namespace: uberon def: "The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]." [GO:0061244] is_a: UBERON:0004199 ! S-shaped body relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005749 name: glomerular tuft namespace: uberon def: "The capillary loops of the kidney that normally function as a filtration unit[MP]." [http://en.wikipedia.org/wiki/Glomerulus, http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron, MP:0005325] subset: pheno_slim synonym: "glomerular capillary tuft" RELATED [] synonym: "glomerulus" RELATED INCONSISTENT [EMAPA:28239] xref: EMAPA:28239 xref: http://en.wikipedia.org/wiki/Glomerulus xref: http://www.snomedbrowser.com/Codes/Details/362217000 relationship: part_of UBERON:0001230 ! glomerular capsule property_value: UBPROP:0000011 "...Soon afterwards, endothelial cells invade to make a capillary knot-like outgrowth, the glomerular tuft, which goes on to form the glomerulus" xsd:string {source="GudMap"} [Term] id: UBERON:0005750 name: glomerular parietal epithelium namespace: uberon def: "A single layer of simple squamous epithelium in the glomerular capsule. Does not function in filtration[UBERON]. outer layer of the glomerular capsule composed of a single layer of simple squamous epithelium[MP]" [https://orcid.org/0000-0002-6601-2165, MP:0011498] subset: pheno_slim subset: vertebrate_core synonym: "Bowman's parietal epithelium" EXACT [MP:0011498] synonym: "capsular epithelium" EXACT [BTO:0002296] synonym: "glomerular capsule parietal layer" EXACT [FMA:74272] synonym: "kidney parietal epithelium" RELATED [EMAPA:35969] synonym: "outer layer of glomerular capsule" EXACT [FMA:74272] synonym: "parietal capsular epithelium" EXACT [MP:0011498] synonym: "parietal epithelial layer" EXACT [ZFA:0005253] synonym: "parietal epithelium of Bowman's capsule" EXACT [MP:0011498] synonym: "parietal layer of Bowman capsule" EXACT [] synonym: "parietal layer of Bowman's capsule" EXACT [MP:0011498] synonym: "parietal layer of glomerular capsule" EXACT [FMA:74272] synonym: "parietal layer of glomerular capsule" EXACT [MP:0011498] synonym: "renal glomerular capsule epithelium" EXACT [ZFA:0005253] xref: BTO:0002296 xref: EMAPA:27979 xref: EMAPA:28260 xref: EMAPA:35969 xref: FMA:74272 xref: http://linkedlifedata.com/resource/umls/id/C0227645 xref: http://www.snomedbrowser.com/Codes/Details/362218005 xref: MA:0002605 xref: NCIT:C33271 xref: TAO:0005253 xref: UMLS:C0227645 {source="ncithesaurus:Parietal_Layer_of_Bowman_s_Capsule"} xref: ZFA:0005253 is_a: UBERON:0004188 ! glomerular epithelium relationship: part_of UBERON:0001230 ! glomerular capsule property_value: IAO:0000116 "TODO - check this. BTO has podocytes under here" xsd:string property_value: UBPROP:0000001 "Simple squamous epithelium that lines the capsule of the renal glomerulus.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005253", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005751 name: visceral layer of glomerular capsule namespace: uberon def: "The inner, or visceral, layer of the renal glomerular capsule, overlying the capillaries, composed of podocytes, and separated from the outer, or parietal, layer by the capsular (Bowman's) space[BTO]. Lies just above the thickened glomerular basement membrane and is made of podocytes. Beneath the visceral layer lie the glomerular capillaries[WP]. inner layer of the glomerular capsule surrounding the capillary endothelial cells and composed of highly specialized epithelial cells (podocytes) that are separated by filtration slits; the visceral layer is separated from the outer parietal layer by the urinary space (also known as the Bowman's or capsular space)[MP]" [BTO:0001515, MP:0011497] subset: inconsistent_with_fma subset: pheno_slim synonym: "Bowman's visceral epithelium" EXACT [MP:0011497] synonym: "glomerular capsule visceral layer" EXACT [MP:0011497] synonym: "inner epithelial layer of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "podocyte layer of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "visceral epithelium of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "visceral epithelium of Bowman's capsule" EXACT [MP:0011497] synonym: "visceral layer of Bowman's capsule" EXACT [MP:0011497] synonym: "visceral layer of glomerular capsule" EXACT [MP:0011497] xref: FMA:74273 xref: http://linkedlifedata.com/resource/umls/id/C0227644 xref: http://www.snomedbrowser.com/Codes/Details/244093000 xref: NCIT:C33879 xref: UMLS:C0227644 {source="ncithesaurus:Visceral_Layer_of_Bowman_s_Capsule"} is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001230 ! glomerular capsule property_value: IAO:0000116 "TODO - check - the BTO class 'glomerular epithelium' is the visceral layer. But GO uses 'glomerular epithelium' as the mereological sum of P+V layers" xsd:string [Term] id: UBERON:0005760 name: urorectal septum namespace: uberon def: "The ridge of mesoderm covered with endoderm that in the early developing embryo partitions the endodermal cloaca into the primary urogenital sinus (ventrally) and the anorectal canal of the hindgut (dorsally); the urorectal septum eventually fuses with the cloacal membrane, dividing it into a dorsal anal membrane and a larger ventral urogenital membrane - this area of fusion is represented in the adult by the perineal body[MP]." [http://en.wikipedia.org/wiki/Urorectal_septum, MP:anna] subset: pheno_slim synonym: "cloacal septum" RELATED [VHOG:0000018] synonym: "septum urorectale" EXACT LATIN [http://en.wikipedia.org/wiki/Urorectal_septum] synonym: "urorectal fold" EXACT [MP:anna] synonym: "urorectal membrane" EXACT [MP:anna] xref: EHDAA2:0002152 xref: EHDAA:5921 xref: EMAPA:17212 xref: http://linkedlifedata.com/resource/umls/id/C1519838 xref: MA:0003235 xref: NCIT:C34323 xref: UMLS:C1519838 {source="ncithesaurus:Urorectal_Septum"} xref: Urorectal:septum xref: VHOG:0000018 relationship: part_of UBERON:0001008 {source="MA"} ! renal system property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray992.png xsd:anyURI property_value: IAO:0000116 "todo - use to define cloacal septation in GO" xsd:string property_value: UBPROP:0000001 "A ridge of mesoderm covered with endoderm that in the early developing embryo divides the endodermal cloaca into the urogenital sinus and the rectum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000018", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urorectal+septum"} property_value: UBPROP:0000003 "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000018", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.388-89 and Figure 300"} [Term] id: UBERON:0005777 name: glomerular basement membrane namespace: uberon def: "the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter" [MGI:anna, MP:0011348] subset: pheno_slim subset: vertebrate_core synonym: "GBM" BROAD ABBREVIATION [] synonym: "glomerular capillary basement membrane" EXACT [MA:0001659] synonym: "glomerular filtration membrane" EXACT [ZFA:0005285] xref: EMAPA:28251 xref: EMAPA:30965 xref: FMA:74274 xref: http://en.wikipedia.org/wiki/Glomerular_basement_membrane xref: http://linkedlifedata.com/resource/umls/id/C0599297 xref: http://www.snomedbrowser.com/Codes/Details/243897006 xref: MA:0001659 xref: NCIT:C32683 xref: TAO:0005285 xref: UMLS:C0599297 {source="ncithesaurus:Glomerular_Basement_Membrane"} xref: ZFA:0005285 relationship: part_of UBERON:0004188 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! glomerular epithelium property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png xsd:anyURI property_value: UBPROP:0000001 "Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005285", ontology="TAO", source="ZFIN:ZDB-PUB-000824-1"} [Term] id: UBERON:0005787 name: lamina densa of glomerular basement membrane namespace: uberon def: "Middle layer of the glomerular basement membrane." [ZFIN:curator] subset: vertebrate_core synonym: "lamina densa" BROAD [ZFA:0005286] synonym: "lamina densa of glomerular basement membrane" EXACT [FMA:74276] synonym: "middle layer of glomerular basement membrane" EXACT [FMA:74276] xref: FMA:74276 xref: http://linkedlifedata.com/resource/umls/id/C1235665 xref: NCIT:C32916 xref: TAO:0005286 xref: UMLS:C1235665 {source="ncithesaurus:Lamina_Densa"} xref: ZFA:0005286 relationship: part_of UBERON:0005777 ! glomerular basement membrane [Term] id: UBERON:0005788 name: lamina rara interna namespace: uberon def: "Layer of the glomerular basement membrane adjacent to the glomerular capillary." [ZFIN:curator] subset: vertebrate_core synonym: "internal layer of glomerular basement membrane" EXACT [FMA:74277] synonym: "lamina interna of glomerular basement membrane" EXACT [FMA:74277] xref: FMA:74277 xref: http://linkedlifedata.com/resource/umls/id/C1517719 xref: NCIT:C32920 xref: TAO:0005287 xref: UMLS:C1517719 {source="ncithesaurus:Lamina_Rara_Interna"} xref: ZFA:0005287 relationship: part_of UBERON:0005777 ! glomerular basement membrane [Term] id: UBERON:0005789 name: lamina rara externa namespace: uberon def: "Layer of the glomerular basement membrane adjacent to the podocytes and capsular space." [ZFIN:curator] subset: vertebrate_core synonym: "external layer of glomerular basement membrane" EXACT [FMA:74275] synonym: "lamina externa of glomerular basement membrane" EXACT [FMA:74275] xref: FMA:74275 xref: http://linkedlifedata.com/resource/umls/id/C1517718 xref: NCIT:C32919 xref: TAO:0005288 xref: UMLS:C1517718 {source="ncithesaurus:Lamina_Rara_Externa"} xref: ZFA:0005288 relationship: part_of UBERON:0005777 ! glomerular basement membrane [Term] id: UBERON:0005792 name: nephric ridge namespace: uberon def: "Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions." [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter27/custom2/deluxe-content.html] synonym: "nephric cord" RELATED [VHOG:0001240] xref: EHDAA2:0001242 xref: EHDAA:1015 xref: EMAPA:16368 xref: VHOG:0001240 relationship: part_of UBERON:0001008 ! renal system property_value: IAO:0000116 "TODO - check ridge vs cord vs nephrogenic cord vs blastema" xsd:string [Term] id: UBERON:0005892 name: mesonephric early distal tubule namespace: uberon def: "The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons." [XB:curator] synonym: "mesonephric ascending limb" RELATED [XAO:0000333] synonym: "mesonephric straight distal segment" RELATED [XAO:0000333] synonym: "straight distal segment" RELATED [XAO:0000333] xref: AAO:0010391 xref: XAO:0000333 is_a: UBERON:0000083 ! mesonephric tubule [Term] id: UBERON:0005912 name: transitional epithelium of major calyx namespace: uberon def: "An urothelium of ureter that is part of a mucosa of major calyx." [OBOL:automatic] synonym: "urothelium of major calyx" EXACT [OBOL:automatic] xref: FMA:263266 is_a: UBERON:0001254 ! urothelium of ureter is_a: UBERON:0004788 ! kidney pelvis urothelium relationship: part_of UBERON:0005007 ! mucosa of major calyx [Term] id: UBERON:0006082 name: fundus of urinary bladder namespace: uberon def: "The base or posterior surface of the urinary bladder contains the trigone of the bladder and the outlet where urine empties through the internal urethral orifice." [http://en.wikipedia.org/wiki/Fundus_of_the_urinary_bladder#Fundus, MP:0011785] subset: pheno_slim synonym: "base of urinary bladder" EXACT [FMA:15908] synonym: "bladder dome" RELATED [EMAPA:35173] synonym: "fundus of bladder" BROAD [FMA:15908] synonym: "fundus vesicae" EXACT LATIN [FMA:15908, FMA:TA] synonym: "urinary bladder base" EXACT [MP:0011785] synonym: "urinary bladder fundus" EXACT [FMA:15908] synonym: "urinary bladder fundus region" EXACT [MA:0001694] xref: EHDAA2:0000582 xref: EHDAA:9330 xref: EMAPA:35173 xref: EMAPA_RETIRED:18322 xref: FMA:15908 xref: Fundus xref: http://linkedlifedata.com/resource/umls/id/C0447584 xref: http://www.snomedbrowser.com/Codes/Details/362226002 xref: MA:0001694 xref: NCIT:C48939 xref: UMLS:C0447584 {source="ncithesaurus:Bladder_Fundus"} xref: VHOG:0001184 relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: UBERON:0006170 name: mesonephric capsule namespace: uberon def: "The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GO:0061285, GOC:mtg_kidney_jan10, https://doi.org/10.1371/journal.pone.0099864] is_a: UBERON:0002015 ! kidney capsule relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0006171 name: renal sinus namespace: uberon def: "A hollowed out area on the medial margin of the kidney. The renal sinus opens at the renal hilum; it contains the renal aa. and vv., major calyces and renal pelvis, perirenal fat" [http://anatomy.uams.edu/anatomyhtml/kidney.html] xref: FMA:15611 xref: http://www.snomedbrowser.com/Codes/Details/362222000 relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0006172 name: rectal diverticulum namespace: uberon def: "The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior" [GO:0039009] synonym: "rectal diverticula" RELATED PLURAL [XAO:0001015] xref: XAO:0001015 relationship: part_of UBERON:0002120 ! pronephros [Term] id: UBERON:0006173 name: pronephric proximal tubule namespace: uberon synonym: "pronephros proximal tubule" EXACT [GO:0039011] is_a: UBERON:0004134 ! proximal tubule is_a: UBERON:0005310 ! pronephric nephron tubule [Term] id: UBERON:0006174 name: pronephric sinus namespace: uberon def: "The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules" [GO:0039012] xref: AAO:0011092 xref: XAO:0000385 is_a: UBERON:0006171 ! renal sinus relationship: part_of UBERON:0002120 ! pronephros property_value: IAO:0000116 "TODO - check relationship to renal sinus, improve definition" xsd:string [Term] id: UBERON:0006175 name: pronephric distal tubule namespace: uberon is_a: UBERON:0004135 ! distal tubule is_a: UBERON:0005310 ! pronephric nephron tubule [Term] id: UBERON:0006182 name: mesonephric glomerular mesangium namespace: uberon def: "The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus" [GO:0061247] is_a: UBERON:0002320 ! glomerular mesangium relationship: part_of UBERON:0005326 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric glomerulus vasculature [Term] id: UBERON:0006183 name: mesonephric glomerular capillary namespace: uberon def: "." [GO:0061249] is_a: UBERON:0004212 ! glomerular capillary relationship: part_of UBERON:0005322 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron relationship: part_of UBERON:0005325 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric glomerulus [Term] id: UBERON:0006189 name: mesonephric connecting tubule namespace: uberon def: "The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros" [GO:0061272] is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0005097 ! renal connecting tubule is_a: UBERON:0005330 ! mesonephric nephron epithelium [Term] id: UBERON:0006190 name: mesonephric distal tubule namespace: uberon def: "The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule" [GO:0061273] is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0004135 ! distal tubule is_a: UBERON:0005330 ! mesonephric nephron epithelium property_value: UBPROP:0000012 "ZFA has terms for developing tubule" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0006192 name: mesonephric proximal tubule namespace: uberon def: "The mesonephric proximal tubule extends from the capsule to the distal tubule" [GO:0061275] is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0004134 ! proximal tubule is_a: UBERON:0005330 ! mesonephric nephron epithelium property_value: UBPROP:0000012 "ZFA has terms for developing tubule" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0006194 name: renal sinus of right kidney namespace: uberon def: "A renal sinus that is part of a right kidney." [OBOL:automatic] synonym: "right renal sinus" EXACT [FMA:17621] xref: FMA:17621 is_a: UBERON:0006171 ! renal sinus relationship: part_of UBERON:0004539 ! right kidney [Term] id: UBERON:0006195 name: renal sinus of left kidney namespace: uberon def: "A renal sinus that is part of a left kidney." [OBOL:automatic] synonym: "left renal sinus" EXACT [FMA:17622] xref: FMA:17622 is_a: UBERON:0006171 ! renal sinus relationship: part_of UBERON:0004538 ! left kidney [Term] id: UBERON:0006196 name: mesonephric sinus namespace: uberon def: "A renal sinus that is part of a mesonephros." [OBOL:automatic] xref: AAO:0011063 xref: XAO:0000381 is_a: UBERON:0006171 ! renal sinus relationship: part_of UBERON:0000080 ! mesonephros property_value: IAO:0000116 "TODO - check relationship to renal sinus, add definition" xsd:string [Term] id: UBERON:0006217 name: cloacal membrane namespace: uberon def: "The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." [http://en.wikipedia.org/wiki/Cloacal_membrane, MP:0011837, MP:anna] subset: emapa_ehdaa2 subset: pheno_slim synonym: "embryonic cloacal membrane" EXACT [] synonym: "membrana cloacalis" RELATED LATIN [http://en.wikipedia.org/wiki/Cloacal_membrane] xref: Cloacal:membrane xref: EHDAA2:0000257 xref: EHDAA:214 xref: EHDAA:2933 xref: EMAPA:16832 xref: FMA:295525 xref: http://linkedlifedata.com/resource/umls/id/C0231056 xref: http://www.snomedbrowser.com/Codes/Details/308826008 xref: NCIT:C34128 xref: UMLS:C0231056 {source="ncithesaurus:Cloacal_Membrane"} xref: VHOG:0001198 relationship: part_of UBERON:0000163 ! embryonic cloaca property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png xsd:anyURI property_value: UBPROP:0000001 "A membrane that separates the proctodeum and the hindgut in the early embryo. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.497, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In mammals, the cloaca exists as an embryonic structure that undergoes septation to become distinct urethral, anal, and genital orifices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="http://bgee.unil.ch/", source="PMID:11830557 De Santa Barbara P, Roberts DJ, Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13. Development (2002)"} [Term] id: UBERON:0006307 name: urogenital membrane namespace: uberon comment: During the 7th week the urorectal septum divides the cloacal membrane into a urogenital membrane (ventrally) and an anal membrane (dorsally) [http://www.embryology.ch/anglais/ugenital/genitexterne01.html] subset: emapa_ehdaa2 xref: EHDAA2:0004025 xref: EHDAA:7011 xref: EMAPA:17378 xref: http://www.snomedbrowser.com/Codes/Details/172994001 xref: RETIRED_EHDAA2:0002141 xref: VHOG:0001187 relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system property_value: UBPROP:0000001 "Ventral part of the cloacal membrane separating the gut from the fetus external environment. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001187", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urogenital+membrane"} [Term] id: UBERON:0006337 name: distal early tubule namespace: uberon def: "Portion of the renal tubule which is just posterior to the proximal straight tubule." [ZFA:0005293] subset: vertebrate_core synonym: "distal early tubules" RELATED PLURAL [ZFA:0005293] synonym: "early distal tubule of capillary loop nephron" RELATED [EMAPA:27788] synonym: "IT1" EXACT ABBREVIATION [XAO:0000287] synonym: "IT2" EXACT ABBREVIATION [XAO:0000287] synonym: "pronephric early distal tubule" RELATED [XAO:0000287] xref: AAO:0011034 xref: EMAPA:27788 xref: EMAPA:28007 xref: TAO:0005293 xref: XAO:0000287 xref: ZFA:0005293 is_a: UBERON:0007685 ! region of nephron tubule property_value: UBPROP:0000001 "Portion of the pronephric tubule that is immediately posterior to the late proximal tubule.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011034", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000012 "in XAO this is pronephric; in ZFA it is an adult structure. we treat it here as generic. consider placing XAO under proneprhic subclass. check relationship with EDCT." xsd:string {external_ontology="XAO"} [Term] id: UBERON:0006341 name: outer renal medulla peritubular capillary namespace: uberon def: "A peritubular capillary that is part of a outer medulla of kidney." [OBOL:automatic] synonym: "kidney outer medulla peritubular capillary" EXACT [MA:0002589] xref: EMAPA:35461 xref: MA:0002589 is_a: UBERON:0005272 ! peritubular capillary relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0006364 name: ureteric bud tip namespace: uberon def: "The terminal end of the ureteric tree; the ureteric tip cells are proliferating immature cells located at the branching points that induce the adjacent cap mesenchyme to undergo nephrogenesis." [http://www.gudmap.org/Organ_Summaries/Metanephros/Ureteric_tip.html, MP:0011760] subset: pheno_slim synonym: "ampulla of ureter" RELATED [EMAPA:27605] synonym: "ureteric ampulla" RELATED [MP:0011760] synonym: "ureteric bud ampulla" RELATED [MP:0011760] synonym: "ureteric tip" EXACT [MA:0002601] xref: EMAPA:27605 xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/Slide10.png xref: MA:0002601 is_a: UBERON:0000083 ! mesonephric tubule relationship: part_of UBERON:0000084 ! ureteric bud property_value: IAO:0000116 "MA placement to be checked" xsd:string [Term] id: UBERON:0006373 name: perihilar interstitium namespace: uberon def: "the part of the renal interstitium surrounding the pelvis" [MGI:anna, MP:0011337] subset: pheno_slim xref: EMAPA:28083 xref: MA:0002618 is_a: UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0001224 {source="MA"} ! renal pelvis [Term] id: UBERON:0006374 name: part of afferent arteriole forming the juxtaglomerular complex namespace: uberon synonym: "part of afferent arteriole forming juxtaglomerular complex" EXACT [MA:0002580] synonym: "renin-producing cells" RELATED [MA:0002580] xref: EMAPA:28269 xref: MA:0002580 relationship: part_of UBERON:0002303 ! juxtaglomerular apparatus relationship: part_of UBERON:0004639 ! renal afferent arteriole [Term] id: UBERON:0006376 name: premacula segment of distal straight tubule namespace: uberon def: "." [http://www.ncbi.nlm.nih.gov/pubmed/14595018, https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376] synonym: "distal straight tubule premacula segment" EXACT [MA:0002628] synonym: "kidney medulla loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "medullary thick ascending limb of Henle's loop" EXACT [MA:th] synonym: "renal medulla loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "renal medulla thick ascending limb" EXACT [MA:th] xref: EMAPA:29671 xref: MA:0002628 is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006541 {source="MA"} ! outer medulla inner stripe loop of Henle relationship: part_of UBERON:0006542 {source="MA"} ! outer medulla outer stripe loop of Henle [Term] id: UBERON:0006517 name: kidney calyx namespace: uberon def: "Recesses of the kidney pelvis which divides into two wide, cup-shaped major renal calices, with each major calix subdivided into 7 to 14 minor calices. Urine empties into a minor calix from collecting tubules, then passes through the major calix, renal pelvis, and ureter to enter the urinary bladder. (From Moore, Clinically Oriented Anatomy, 3d ed, p211)" [MESH:A05.810.453.537.503] subset: pheno_slim synonym: "calices renales" EXACT LATIN [] synonym: "calices renales" RELATED PLURAL [] synonym: "calyx" BROAD [EMAPA:18676] synonym: "renal calix" EXACT [] synonym: "renal calyx" EXACT [MA:0000369] xref: EMAPA:18676 xref: FMA:284558 xref: GAID:427 xref: http://linkedlifedata.com/resource/umls/id/C0022651 xref: http://www.snomedbrowser.com/Codes/Details/276832000 xref: MA:0000369 xref: MESH:D007670 xref: NCIT:C12927 xref: UMLS:C0022651 {source="ncithesaurus:Renal_Calyx"} relationship: part_of UBERON:0001224 ! renal pelvis property_value: UBPROP:0000007 "calyceal" xsd:string [Term] id: UBERON:0006534 name: renal convoluted tubule namespace: uberon def: "Any region of a nephron tubule that is convoluted. Examples: distal convoluted tubule, proximal convoluted tuble." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "convoluted tubule" EXACT [] synonym: "kidney convoluted tubule" EXACT [MA:0001665] xref: Convoluted:tubule xref: EMAPA:35725 xref: http://linkedlifedata.com/resource/umls/id/C1707510 xref: http://www.snomedbrowser.com/Codes/Details/361333002 xref: MA:0001665 xref: NCIT:C49479 xref: UMLS:C1707510 {source="ncithesaurus:Convoluted_Tubule"} is_a: UBERON:0007685 ! region of nephron tubule [Term] id: UBERON:0006541 name: outer medulla inner stripe loop of Henle namespace: uberon def: "A loop of Henle that is part of a kidney outer medulla inner stripe." [OBOL:automatic] xref: EMAPA:29679 xref: MA:0002627 is_a: UBERON:0034996 ! outer renal medulla loop of Henle relationship: part_of UBERON:0004201 ! kidney outer medulla inner stripe [Term] id: UBERON:0006542 name: outer medulla outer stripe loop of Henle namespace: uberon def: "A loop of Henle that is part of a kidney outer medulla outer stripe." [OBOL:automatic] xref: EMAPA:29665 xref: MA:0002630 is_a: UBERON:0034996 ! outer renal medulla loop of Henle relationship: part_of UBERON:0004202 ! kidney outer medulla outer stripe [Term] id: UBERON:0006544 name: kidney vasculature namespace: uberon def: "A vasculature that is part of a kidney." [OBOL:automatic] subset: vertebrate_core xref: EMAPA:28457 xref: TAO:0005305 xref: ZFA:0005305 relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0006553 name: renal duct namespace: uberon def: "A tube in the kidney that collect and transport urine." [ZFIN:ZDB-PUB-071029-9] xref: TAO:0005289 xref: ZFA:0005289 relationship: part_of UBERON:0002113 ! kidney property_value: UBPROP:0000012 "in ZFA this is defined as part of mesonephros" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0006555 name: excretory tube namespace: uberon def: "A tube that is part of a excretory system." [OBOL:automatic] relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0006565 name: female urethral meatus namespace: uberon def: "A urethral meatus that is part of a female urethra[Automatically generated definition]." [http://en.wikipedia.org/wiki/External_urethral_orifice_(female), OBOL:automatic] synonym: "distal urethral opening of female" RELATED [EMAPA:36453] synonym: "external orifice of female urethra" EXACT [FMA:85266] synonym: "external urethral orifice (female)" EXACT [FMA:85266] synonym: "female urethral meatus" EXACT [FMA:85266] synonym: "ostium urethrae externum (urethra feminina)" EXACT LATIN [FMA:85266, FMA:TA] synonym: "urethral meatus of clitoral urethra" EXACT [EMAPA:36453] synonym: "urethral opening of clitoral urethra" RELATED [EMAPA:36453] xref: EMAPA:36453 xref: FMA:85266 xref: http://en.wikipedia.org/wiki/External_urethral_orifice_(female) xref: http://www.snomedbrowser.com/Codes/Details/279479008 xref: MA:0002639 is_a: UBERON:0012240 ! urethral meatus relationship: part_of UBERON:0001334 ! female urethra property_value: UBPROP:0000001 "The external urethral orifice (urinary meatus) is the external opening of the urethra, from which urine is ejected during urination. It is placed about 2.5 cm behind the glans clitoridis and immediately in front of that of the vagina; it usually assumes the form of a short, sagittal cleft with slightly raised margins. To its left and right are the openings of the Skene's ducts." xsd:string {source="http://en.wikipedia.org/wiki/External_urethral_orifice_(female)"} [Term] id: UBERON:0006851 name: renal cortex peritubular capillary namespace: uberon def: "A peritubular capillary that is part of a cortex of kidney." [OBOL:automatic] synonym: "kidney cortex peritubular capillary" EXACT [MA:0002590] xref: EMAPA:37488 {source="MA:th"} xref: MA:0002590 is_a: UBERON:0005272 ! peritubular capillary relationship: part_of UBERON:0001225 ! cortex of kidney [Term] id: UBERON:0006852 name: glomerular visceral epithelium namespace: uberon synonym: "podocyte layer" RELATED [MA:0002607] xref: EMAPA:28254 xref: MA:0002607 is_a: UBERON:0004188 ! glomerular epithelium [Term] id: UBERON:0006853 name: renal cortex tubule namespace: uberon def: "A region of nephron tubule that is part of a cortex of kidney." [OBOL:automatic] synonym: "cortical tubule" RELATED [MA:0002609] synonym: "kidney cortex tubule" EXACT [MA:0002609] xref: EMAPA:18976 xref: MA:0002609 is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0006854 name: distal straight tubule postmacula segment namespace: uberon def: "." [https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376] synonym: "cortical thick ascending limb of Henle's loop" EXACT [MA:th] synonym: "kidney cortex loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "renal cortex loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "renal cortex thick ascending limb" EXACT [MA:th] xref: EMAPA:28402 xref: MA:0002615 is_a: UBERON:0006853 ! renal cortex tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle [Term] id: UBERON:0006855 name: muscular coat of ureter namespace: uberon def: "A muscular coat that is part of a ureter." [OBOL:automatic] synonym: "muscular coat of ureter" EXACT [FMA:15893] synonym: "muscular layer of ureter" EXACT [FMA:15893] synonym: "muscularis of ureter" EXACT [FMA:15893] synonym: "tunica muscularis (ureter)" EXACT LATIN [FMA:TA] synonym: "tunica muscularis ureteris" EXACT LATIN [FMA:TA] synonym: "ureteral smooth muscle layer" RELATED [EMAPA:28567] xref: EMAPA:28811 xref: FMA:15893 xref: http://www.snomedbrowser.com/Codes/Details/3563003 xref: MA:0002654 relationship: part_of UBERON:0009916 {source="FMA"} ! wall of ureter [Term] id: UBERON:0006856 name: interrenal gland namespace: uberon def: "Structures in fishes homologous to the cortical tissue of the mammalian adrenal gland; they are in close proximity to or imbedded in the head kidney." [BTO:0000808, https://doi.org/10.1242/dev.00427] subset: organ_slim synonym: "interrenal" RELATED [http://dev.biologists.org/content/130/10/2107.full] synonym: "interrenal bodies" RELATED [] synonym: "interrenal body" RELATED [BTO:0000808] synonym: "interrenal gland" RELATED [] synonym: "interrenal tissue" RELATED [] xref: BTO:0000808 xref: GAID:1227 xref: MESH:D007401 xref: TAO:0001345 xref: VHOG:0001141 xref: ZFA:0001345 relationship: part_of UBERON:0007132 {source="ZFA"} ! head kidney property_value: IAO:0000116 "check isa - not a true gland? There are two types of interrenal cells identified (1) The noradrenaline type, which contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. (2) The adrenaline type, in which the vesicles are smaller and contain homogenous electron-lucent granules that are separated from the vesicular membrane by a visible -- halo http://dev.biologists.org/content/130/10/2107.full" xsd:string property_value: UBPROP:0000001 "An epithelial structure consisting of steroid producing cells interposed with chromaffin cells embedded within the head kidney. The interrenal gland is thought to be the equivalent of the mammalian adrenal cortex in zebrafish. Hsu et al. 2003.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001345", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001141", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9"} [Term] id: UBERON:0006857 name: interrenal primordium namespace: uberon xref: TAO:0001346 xref: ZFA:0001346 relationship: part_of UBERON:0000080 ! mesonephros property_value: IAO:0000116 "consider ceding to TAO/ZFA - however, structure also present in cyclostomes" xsd:string property_value: UBPROP:0000011 "splanchnic mesoderm adjacent to urogenital ridge" xsd:string [Term] id: UBERON:0006912 name: urinary bladder muscularis mucosa namespace: uberon def: "A thin layer of smooth muscle within the bladder lamina propria." [http://www.pathologyoutlines.com/topic/bladderhistology.html, NCIT:C32207] synonym: "muscularis mucosa of bladder" BROAD [EMAPA:28619] synonym: "muscularis mucosa of urinary bladder" EXACT [OBOL:automatic] xref: EMAPA:28619 xref: http://linkedlifedata.com/resource/umls/id/C1511195 xref: MA:0002490 xref: NCIT:C32207 xref: UMLS:C1511195 {source="ncithesaurus:Bladder_Muscularis_Mucosa"} is_a: UBERON:0004228 ! urinary bladder smooth muscle relationship: part_of UBERON:0001261 ! lamina propria of urinary bladder property_value: UBPROP:0000010 "One study observed that in humans this layer is frequently discontinuous, sparse or sometimes hyperplastic or absent[PMID:3631381]" xsd:string [Term] id: UBERON:0006972 name: nephridium namespace: uberon def: "An exceretory tubule that usually opens to the exterior by a nephridiopore. The inner end of the tubule may be blind, ending in flame cells (protonephridium) or may open into the coelom through a ciliated funnel (metanephridium)." [http://en.wikipedia.org/wiki/Nephridium] xref: BTO:0000923 xref: http://en.wikipedia.org/wiki/Nephridium is_a: UBERON:0006555 ! excretory tube [Term] id: UBERON:0006973 name: protonephridium namespace: uberon def: "A network of dead-end tubules lacking internal openings found in the Phylums Platyhelminthes, kinorhyncha and Rotifera." [http://en.wikipedia.org/wiki/Nephridium#Metanephridia] comment: The ends are called flame cells (if cilliated) or solenocytes (if flagellated); they function in osmoregulation and ionoregulation. The terminal cells are located at the blind end of the protonephridium. Each cell has one or more cilia and their beating inside the protonephridial tube creates an outward going current and hence a partial pressurization in the blind of the tube. Because of this pressurization drives waste fluids from the inside of the animal, they are pulled through small perforations in the terminal cells and into the protonephridium. The perforations in the terminal cell are large enough for small molecules to pass, but larger proteins are retained within the animal. From the bottom of the protonephridium the solutes are led through the tube, formed by the canal cells, and exits the animal from a small opening formed by the nephridiopore. Selective reabsorption of useful molecules by the canal cells occurs as the solutes pass down the tubule. Protonephridia are generally found in basal organisms such as flatworms. Protonephridia likely first arose as a way to cope with a hypotonic environment by removing excess water from the organism (osmoregulation). Their use as excretory/ionoregulatory structures likely arose secondarily xref: BILA:0000126 xref: Metanephridia is_a: UBERON:0006972 ! nephridium [Term] id: UBERON:0006974 name: metanephridium namespace: uberon def: "A type of excretory gland or nephridium found in many types of invertebrates such as Annelids, Arthropods and Molluscs. It typically consists of a ciliated funnel opening into the body cavity or coelom connected to a duct which may be variously glandularized, folded or expanded (vesiculate) and which typically opens to the organism's exterior. These ciliated tubules pump water carrying surplus ions, metabolic waste, toxins from food, and useless hormones out of the organism through openings known as nephrostomes. This waste is passed out of the body at the nephridiopore. The primary urine produced by filtration of blood (or a similar functioning fluid) is modified into secondary urine through selective reabsorption by the cells lining the metanephridium. In many earthworms the nephridial ducts open into the digestive tract instead, a condition known as enteronephry." [http://en.wikipedia.org/wiki/Nephridium#Metanephridia] xref: BILA:0000127 xref: Metanephridia is_a: UBERON:0006972 ! nephridium [Term] id: UBERON:0007132 name: head kidney namespace: uberon def: "Teleost head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis[ZFA,modified]." [https://doi.org/10.1242/dev.00427, ZFIN:ZDB-PUB-040923-1] subset: organ_slim synonym: "anterior kidney" EXACT [ZFA:0000669] synonym: "kidney marrow" EXACT [ZFA:0000669] xref: BTO:0005189 xref: TAO:0000669 xref: ZFA:0000669 relationship: part_of UBERON:0002113 ! kidney property_value: UBPROP:0000001 "The zebrafish head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. Davidson and Zon 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000669", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "in GO, head kidney isa pronephros. Modified the ZFA relationships - the HK is derived from the anterior part of the pronephros and persists until adulthood" xsd:string {external_ontology="GO"} [Term] id: UBERON:0007179 name: basal cell layer of urothelium namespace: uberon synonym: "basal cell layer of uroepithelium" EXACT [FMA:84154] xref: EMAPA:28806 xref: FMA:84154 relationship: part_of UBERON:0000365 ! urothelium [Term] id: UBERON:0007298 name: pronephric proximal convoluted tubule namespace: uberon def: "A proximal convoluted tubule that is part of a pronephros." [OBOL:automatic] xref: TAO:0002238 xref: ZFA:0001620 is_a: UBERON:0001287 ! proximal convoluted tubule is_a: UBERON:0005310 ! pronephric nephron tubule [Term] id: UBERON:0007306 name: pronephric glomerular capillary namespace: uberon def: "A glomerular capillary that is part of a pronephros." [OBOL:automatic] xref: TAO:0005309 xref: ZFA:0005309 is_a: UBERON:0004212 ! glomerular capillary relationship: part_of UBERON:0004739 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! pronephric glomerulus relationship: part_of UBERON:0005309 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! pronephric nephron [Term] id: UBERON:0007307 name: pronephric glomerular basement membrane namespace: uberon def: "A glomerular basement membrane that is part of a pronephros." [OBOL:automatic] synonym: "pronephric glomerular filtration membrane" EXACT [ZFA:0005313] xref: TAO:0005313 xref: ZFA:0005313 is_a: UBERON:0005777 ! glomerular basement membrane relationship: part_of UBERON:0004739 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! pronephric glomerulus [Term] id: UBERON:0007308 name: pronephric distal early tubule namespace: uberon def: "A distal early tubule that is part of a pronephros." [OBOL:automatic] synonym: "pronephric distal early tubules" RELATED PLURAL [ZFA:0001622] xref: TAO:0002236 xref: ZFA:0001622 is_a: UBERON:0005310 ! pronephric nephron tubule is_a: UBERON:0006337 ! distal early tubule [Term] id: UBERON:0007653 name: capillary loop nephron namespace: uberon def: "Developing nephron where the developing glomerular capsule has been invaded by a glomerular capillary loop called the glomerular tuft." [ZFIN:curator] synonym: "developing capillary loop stage nephron" EXACT [EMAPA:28506] synonym: "stage III nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Capillary_loop.html] xref: EMAPA:28506 xref: ZFA:0005590 is_a: UBERON:0010532 {source="cjm"} ! primitive nephron property_value: IAO:0000116 "TODO" xsd:string [Term] id: UBERON:0007654 name: maturing nephron namespace: uberon synonym: "stage IV nephron" RELATED [EMAPA:28485] xref: EMAPA:28485 is_a: UBERON:0010532 {source="cjm"} ! primitive nephron relationship: part_of UBERON:0001225 {source="EMAPA"} ! cortex of kidney property_value: IAO:0000116 "TODO" xsd:string [Term] id: UBERON:0007684 name: uriniferous tubule namespace: uberon def: "functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule." [ISBN:0073040584] xref: FMA:17691 is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006555 ! excretory tube [Term] id: UBERON:0007685 name: region of nephron tubule namespace: uberon synonym: "region of renal tubule" RELATED [FMA:17692] synonym: "renal tubule region" EXACT [FMA:17692] xref: FMA:17692 is_a: UBERON:0001231 ! nephron tubule property_value: UBPROP:0000012 "consider moving MA:0000377 renal tubule here, as it includes the various segments (proximal etc) as subclasses, not parts" xsd:string {external_ontology="MA"} [Term] id: UBERON:0008404 name: proximal tubular epithelium namespace: uberon def: "The cells lining the proximal tubule are cuboidal epithelial cells with deep basal membrane invaginations that provide a large basal surface area. The long microvilli (the brush border) lining the tubule lumen, maximize luminal surface area and make these cells ideally suited for both reabsorptive and secretory functions." [_Chapter_3, Renal_Physiology:Section_7] synonym: "epithelium of proximal convoluted tubule" EXACT [FMA:64808] synonym: "epithelium of proximal renal tubule" EXACT [FMA:64808] synonym: "proximal renal tubule epithelium" EXACT [FMA:64808] synonym: "proximal tubule epithelium" RELATED [BTO:0003576] synonym: "proximale tubular epithelium" EXACT [BTO:0003576] xref: BTO:0003576 xref: FMA:64808 is_a: UBERON:0004810 ! nephron tubule epithelium relationship: part_of UBERON:0004134 ! proximal tubule property_value: IAO:0000116 "See https://github.com/obophenotype/uberon/issues/1305" xsd:string [Term] id: UBERON:0008408 name: distal tubular epithelium namespace: uberon def: "An epithelium that is part of a distal tubule." [OBOL:automatic] synonym: "distal tubule epithelium" RELATED [BTO:0003948] xref: BTO:0003948 is_a: UBERON:0004810 ! nephron tubule epithelium relationship: part_of UBERON:0004135 {source="BTO"} ! distal tubule property_value: IAO:0000116 "See https://github.com/obophenotype/uberon/issues/1305" xsd:string [Term] id: UBERON:0008716 name: hilum of kidney namespace: uberon def: "An opening on medial margin of the kidney leading into the renal sinus. he renal vessels enter/leave the kidney at the hilum; the renal pelvis leaves the kidney at the hilum." [http://anatomy.uams.edu/anatomyhtml/kidney.html] synonym: "hilar area of the kidney" EXACT [] synonym: "renal hilum" EXACT [FMA:15610] xref: FMA:15610 xref: galen:HilumOfKidney xref: http://en.wikipedia.org/wiki/Hilum_of_kidney xref: http://linkedlifedata.com/resource/umls/id/C0227608 xref: http://www.snomedbrowser.com/Codes/Details/279370006 xref: NCIT:C32740 xref: UMLS:C0227608 {source="ncithesaurus:Hilar_Area_of_the_Kidney"} relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0008987 name: renal parenchyma namespace: uberon def: "The functional tissue of the kidney, consisting of the nephrons." [BTO:0003604] synonym: "kidney parenchyma" RELATED [BTO:0003604] synonym: "parenchyma of kidney" EXACT [FMA:15574] xref: BTO:0003604 xref: FMA:15574 xref: http://www.snomedbrowser.com/Codes/Details/29704000 relationship: part_of UBERON:0002113 {source="FMA"} ! kidney [Term] id: UBERON:0009010 name: periurethral tissue namespace: uberon def: "Any portion of tissue that surrounds a urethra." [UBERON:cjm] xref: BTO:0005081 xref: http://www.snomedbrowser.com/Codes/Details/256880003 relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: UBERON:0009035 name: renal straight tubule namespace: uberon def: "Any region of a nephron tubule that is straight. Examples: distal convoluted tubule, proximal convoluted tuble." [http://orcid.org/0000-0002-6601-2165] synonym: "kidney straight tubule" EXACT [MA:0002634] synonym: "straight tubule" EXACT [] xref: EMAPA:37489 {source="MA:th"} xref: http://en.wikipedia.org/wiki/Tubuli_seminiferi_recti xref: http://www.snomedbrowser.com/Codes/Details/245151008 xref: MA:0002634 is_a: UBERON:0007685 ! region of nephron tubule [Term] id: UBERON:0009089 name: inner medulla vasa recta descending limb namespace: uberon xref: KUPO:0001003 relationship: part_of UBERON:0004776 {source="KUPO"} ! inner renal medulla vasa recta property_value: UBPROP:0000012 "This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the inner medullar parallel to the descending limb" xsd:string {external_ontology="CL"} [Term] id: UBERON:0009090 name: outer medulla vasa recta descending limb namespace: uberon xref: KUPO:0001004 relationship: part_of UBERON:0004775 {source="KUPO"} ! outer renal medulla vasa recta property_value: UBPROP:0000012 "This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the outer medullar parallel to the descending limb" xsd:string {external_ontology="CL"} [Term] id: UBERON:0009092 name: inner medulla vasa recta ascending limb namespace: uberon xref: KUPO:0001006 relationship: part_of UBERON:0004776 {source="KUPO"} ! inner renal medulla vasa recta property_value: UBPROP:0000012 "This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the inner medulla parallel to the ascending limb" xsd:string {external_ontology="CL"} [Term] id: UBERON:0009093 name: outer medulla vasa recta ascending limb namespace: uberon xref: KUPO:0001007 relationship: part_of UBERON:0004775 {source="KUPO"} ! outer renal medulla vasa recta property_value: UBPROP:0000012 "This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the outer medulla parallel to the ascending limb" xsd:string {external_ontology="CL"} [Term] id: UBERON:0009095 name: tip of renal papilla namespace: uberon synonym: "papillary tip" EXACT [KUPO:0001009] synonym: "papillary tips" EXACT PLURAL [KUPO:0001009] xref: KUPO:0001009 relationship: part_of UBERON:0001228 {source="KUPO"} ! renal papilla [Term] id: UBERON:0009201 name: nephric duct namespace: uberon def: "A nephric duct is a tube that drains a primitive kidney[GO]." [GO:0072176] comment: pronephric duct or mesonephric duct xref: EMAPA:16577 xref: Wolffian:duct is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006553 ! renal duct is_a: UBERON:0006555 ! excretory tube [Term] id: UBERON:0009622 name: pronephric proximal straight tubule namespace: uberon def: "A proximal straight tubule that is part of a pronephros." [ZFIN:ZDB-PUB-071029-9] synonym: "proximal straight tubules" RELATED PLURAL [TAO:0002239] xref: TAO:0002239 xref: ZFA:0001621 is_a: UBERON:0001290 ! proximal straight tubule is_a: UBERON:0005310 ! pronephric nephron tubule relationship: part_of UBERON:0006173 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! pronephric proximal tubule [Term] id: UBERON:0009650 name: cortical arch of kidney namespace: uberon def: "The portions of renal substance (cortex) intervening between the bases of the pyramids and the capsule of the kidney." [http://www.medilexicon.com/medicaldictionary.php?t=5968] synonym: "cortex proper of kidney" RELATED [FMA:17876] synonym: "cortical arches of kidney" RELATED PLURAL [] synonym: "renal cortex proper" EXACT [FMA:17876] synonym: "renal cortical arch" EXACT [FMA:17876] xref: EMAPA:37486 {source="MA:th"} xref: FMA:17876 xref: http://linkedlifedata.com/resource/umls/id/C1511525 xref: MA:0001650 xref: NCIT:C32385 xref: UMLS:C1511525 {source="ncithesaurus:Cortical_Arch"} is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002189 {source="MA"} ! outer cortex of kidney [Term] id: UBERON:0009651 name: nephron tubule basement membrane namespace: uberon def: "A basement membrane that is part of a nephron tubule." [OBOL:automatic] synonym: "kidney tubule basement membrane" EXACT [MA:0001680] synonym: "renal tubular basement membrane" EXACT [] synonym: "renal tubule basement membrane" EXACT [MA:0001680] xref: EMAPA:37490 {source="MA:th"} xref: http://linkedlifedata.com/resource/umls/id/C1709901 xref: http://www.snomedbrowser.com/Codes/Details/245251000 xref: MA:0001680 xref: NCIT:C49273 xref: UMLS:C1709901 {source="ncithesaurus:Renal_Tubule_Basement_Membrane"} relationship: part_of UBERON:0004810 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! nephron tubule epithelium [Term] id: UBERON:0009669 name: embryonic cloacal lumen namespace: uberon def: "An anatomical space that surrounded_by a embryonic cloaca." [OBOL:automatic] xref: EHDAA2:0004586 relationship: part_of UBERON:0000163 ! embryonic cloaca [Term] id: UBERON:0009773 name: renal tubule namespace: uberon def: "A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GO:0061333, GOC:dph, GOC:mtg_kidney_jan10, https://doi.org/10.1371/journal.pone.0099864] subset: grouping_class subset: pheno_slim synonym: "renal tubule (generic)" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tubule of excretory system" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] is_a: UBERON:0006555 ! excretory tube property_value: IAO:0000232 "this class groups vertebrate nephron tubules with analagous structures such as insect Malpighian tubules" xsd:string [Term] id: UBERON:0009844 name: urogenital sinus lumen namespace: uberon def: "An anatomical space that surrounded_by a primitive urogenital sinus." [OBOL:automatic] xref: EHDAA2:0002142 relationship: part_of UBERON:0000164 ! primitive urogenital sinus [Term] id: UBERON:0009846 name: embryonic cloacal epithelium namespace: uberon def: "An epithelium that is part of a embryonic cloaca." [OBOL:automatic] synonym: "cloacal epithelium" BROAD [EHDAA2:0004585] xref: EHDAA2:0004585 relationship: part_of UBERON:0000163 ! embryonic cloaca [Term] id: UBERON:0009847 name: prostate field namespace: uberon def: "A specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop." [GO:0060515, GOC:dph, http://www.ncbi.nlm.nih.gov/pubmed/18977204] synonym: "prostate primordium" RELATED [] relationship: part_of UBERON:0004902 {source="http://www.ncbi.nlm.nih.gov/pubmed/18977204"} ! urogenital sinus epithelium [Term] id: UBERON:0009866 name: Hatschek's nephridium namespace: uberon def: "An unpaired kidney whose duct opens into the anterior pharynx. It can be seen as a deep ciliated fossa on the dorsal midline of the buccal cavity (mouth). Among other things, it secrets mucus which entraps food particles from the water[WP]." [http://orcid.org/0000-0002-6601-2165] subset: organ_slim relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0009871 name: nephrogenic zone namespace: uberon def: "Outer portion of the renal cortex. Site of formation of medullary and cortical elements." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cortical nephrogenic niche" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/29449449] synonym: "cortical nephrogenic zone" EXACT [http://www.ncbi.nlm.nih.gov/pubmed/29449449] synonym: "nephrogenic tissue" RELATED [] xref: EMAPA:27721 xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/NZ.png xref: MA:0002996 relationship: part_of UBERON:0001225 ! cortex of kidney property_value: UBPROP:0000008 "see http://www.ncbi.nlm.nih.gov/pubmed/12761251 for description of nephrogenic zone in dogfish." xsd:string [Term] id: UBERON:0009883 name: medullary ray namespace: uberon def: "A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla." [http://en.wikipedia.org/wiki/Bone_marrow_of_ovaryry_ray_(anatomy), MP:0011347] subset: pheno_slim synonym: "Ferrein's pyramid" EXACT [MP:0011347] synonym: "kidney medullary ray" EXACT [MP:0011347] synonym: "renal medullary ray" EXACT [MP:0011347] xref: BTO:0001155 xref: EMAPA:37906 {source="MA:th"} xref: FMA:74299 xref: http://en.wikipedia.org/wiki/Bone_marrow_of_ovaryry_ray_(anatomy) relationship: part_of UBERON:0001225 {source="MP"} ! cortex of kidney property_value: UBPROP:0000012 "FMA says parenchyma, MP says cortex" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000013 "Their name is potentially misleading -- the 'medullary' refers to their destination, not their location. They are located only in the renal cortex, and not in the renal medulla" xsd:string [Term] id: UBERON:0009913 name: renal lobe namespace: uberon def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [http://en.wikipedia.org/wiki/Renal_lobe, MP:0011381] subset: pheno_slim synonym: "kidney lobe" EXACT [MP:0011381] synonym: "lobi renales" RELATED LATIN [http://en.wikipedia.org/wiki/Renal_lobe] synonym: "lobi renalis" EXACT PLURAL [http://en.wikipedia.org/wiki/Renal_lobe] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17881 xref: http://linkedlifedata.com/resource/umls/id/C0736382 xref: NCIT:C32894 xref: Renal:lobe xref: UMLS:C0736382 {source="ncithesaurus:Kidney_Lower_Lobe"} relationship: part_of UBERON:0002113 ! kidney property_value: depicted:by Kidney:PioM.png xsd:anyURI property_value: IAO:0000116 "todo - add has_part relationships." xsd:string property_value: UBPROP:0000008 "human kidneys have multilobar (multipyramidal) architecture while mice and rats have unilobar (unipyramidal) kidneys" xsd:string {source="MP"} [Term] id: UBERON:0009914 name: renal lobule namespace: uberon def: "The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys" [http://en.wikipedia.org/wiki/Cortical_lobule, MP:0011382] comment: Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis subset: pheno_slim synonym: "cortical lobule" RELATED [http://en.wikipedia.org/wiki/Cortical_lobule, MP:0011382] synonym: "cortical lobule of kidney" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "kidney lobule" EXACT [MP:0011382] synonym: "lobuli corticales renis" RELATED LATIN [http://en.wikipedia.org/wiki/Cortical_lobule] synonym: "lobulus corticalis renalis" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "lobulus renalis" EXACT [] synonym: "renal cortical lobule" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "reniculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renunculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: Cortical:lobule xref: FMA:17670 xref: http://www.snomedbrowser.com/Codes/Details/361330004 relationship: part_of UBERON:0009913 {source="FMA"} ! renal lobe [Term] id: UBERON:0009916 name: wall of ureter namespace: uberon def: "An anatomical wall that is part of a ureter." [OBOL:automatic] synonym: "ureteral wall" EXACT [FMA:15888] xref: FMA:15888 xref: http://www.snomedbrowser.com/Codes/Details/279397004 relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0009917 name: kidney corticomedullary boundary namespace: uberon def: "The region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary" [MP:0011376] subset: pheno_slim xref: EMAPA:37886 {source="MA:th"} relationship: part_of UBERON:0002113 {source="MP"} ! kidney [Term] id: UBERON:0009919 name: ureter smooth muscle namespace: uberon def: "The smooth muscle tissue surrounding the epithelium of the ureter" [MP:0011426] subset: pheno_slim synonym: "ureteral smooth muscle" EXACT [MP:0011426] synonym: "ureteral smooth muscle layer" EXACT [EMAPA:28844] xref: EMAPA:28811 relationship: part_of UBERON:0006855 ! muscular coat of ureter [Term] id: UBERON:0009958 name: bladder lumen namespace: uberon def: "A anatomical space that is enclosed by a urinary bladder." [OBOL:automatic] synonym: "bladder cavity" EXACT [FMA:15924] synonym: "cavity of urinary bladder" EXACT [FMA:15924] synonym: "lumen of urinary bladder" EXACT [FMA:15924] synonym: "urinary bladder lumen" EXACT [FMA:15924] xref: EHDAA2:0004058 xref: FMA:15924 xref: galen:UrinaryBladderCavity xref: http://www.snomedbrowser.com/Codes/Details/279405003 relationship: part_of UBERON:0001255 {source="FMA"} ! urinary bladder [Term] id: UBERON:0009962 name: excretory gland namespace: uberon def: "A gland that discharges its secretion through a duct opening on an internal or external surface of the body, as a lacrimal gland." [Dorlands_Medical_Dictionary:MerckSource] synonym: "renal gland" NARROW [https://github.com/obophenotype/uberon/issues/1450] xref: BTO:0000431 relationship: part_of UBERON:0001008 ! renal system property_value: IAO:0000116 "TODO - child terms" xsd:string [Term] id: UBERON:0009963 name: antennal gland namespace: uberon def: "Excretory gland situated in the basal article of the antennal peduncle. It functions to rehulate ionic balance" [BTO:0000075, https://orcid.org/0000-0002-6601-2165] synonym: "green gland" EXACT [] xref: BTO:0000075 is_a: UBERON:0009962 {source="BTO"} ! excretory gland property_value: IAO:0000116 "cede this term to Arthropod AO" xsd:string property_value: IAO:0000116 "consider also classifying this as a renal tubule - or separate terms for coiled/nephridial canal" xsd:string [Term] id: UBERON:0009964 name: crustacean maxillary gland namespace: uberon def: "Excretory organ in maxillary segment with duct opening on maxilla." [http://crustacea.nhm.org/glossary/define.html] is_a: UBERON:0009962 {source="BTO"} ! excretory gland property_value: IAO:0000116 "cede this term to Arthropod AO" xsd:string property_value: UBPROP:0000008 "consider generalizing to include millipedes, centipedes. Function: Two different excretory organs are found among crustaceans: the antennal gland and the maxillary gland. Both have the same basic structure: an end sac and a convoluted duct that may expand into a bladder before opening to the outside. In most adult crustaceans only one or the other gland functions. The functional gland may change during the life cycle. Terminology note: http://crustacea.nhm.org/glossary/define.html?termID=327 suggests green gland as the generic term and antennal as the decapoda term" xsd:string [Term] id: UBERON:0009965 name: coxal gland namespace: uberon def: "A gland found in some arthropods, for collecting and excreting urine. The gland comprises an end sac (saccule), a long duct (labyrinth) and a terminal bladder (reservoir). There is generally only one pair (two in some spiders), and they open on the coxae of the walking legs[WP]." [http://en.wikipedia.org/wiki/Coxal_gland] xref: Coxal:gland xref: SPD:0000116 xref: TADS:0000080 is_a: UBERON:0009962 {source="BTO"} ! excretory gland property_value: IAO:0000116 "cede this term to Arthropod AO" xsd:string property_value: UBPROP:0000008 "They are found in all arachnids (with the exception of some Acari), and in other chelicerates, such as horseshoe crabs. Homology: The coxal gland is thought to be homologous with the antennal gland of crustaceans" xsd:string [Term] id: UBERON:0009972 name: ureteropelvic junction namespace: uberon def: "The junction between the ureter and the renal pelvis of the kidney" [MP:0011487] subset: pheno_slim synonym: "pelviureteric junction" EXACT [FMA:15898] synonym: "pelvoureteric junction" EXACT [] xref: EMAPA:37782 {source="MA:th"} xref: FMA:15898 xref: http://www.snomedbrowser.com/Codes/Details/264130006 xref: MA:0003021 xref: NCIT:C106203 relationship: part_of UBERON:0001008 {source="MP"} ! renal system [Term] id: UBERON:0009973 name: ureterovesical junction namespace: uberon def: "The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney" [MP:0011488] subset: pheno_slim synonym: "vesico-ureteral junction" EXACT [MA:0003020] synonym: "vesico-ureteric junction" EXACT [] synonym: "vesicoureteric junction" EXACT [] xref: EMAPA:37783 {source="MA:th"} xref: FMA:15899 xref: http://www.snomedbrowser.com/Codes/Details/261187001 xref: MA:0003020 xref: NCIT:C106202 relationship: part_of UBERON:0001008 {source="MP"} ! renal system [Term] id: UBERON:0010151 name: duct of bulbourethral gland namespace: uberon def: "A duct that is part of a bulbo-urethral gland." [OBOL:automatic] synonym: "bulbourethral gland duct" EXACT [FMA:20091] synonym: "duct of bulbo-urethral gland" EXACT [FMA:20091] synonym: "ductus glandulae bulbourethralis" EXACT LATIN [FMA:TA] xref: FMA:20091 xref: http://www.snomedbrowser.com/Codes/Details/279709005 relationship: part_of UBERON:0002366 ! bulbo-urethral gland [Term] id: UBERON:0010181 name: straight venules of kidney namespace: uberon def: "The straight venules of kidney are branches from the plexuses at the apices of the medullary pyramids, formed by the terminations of the arteriae rectae. They run outward in a straight course between the tubes of the medullary substance, and joining, as above stated, the interlobular veins, form venous arcades; these in turn unite and form veins which pass along the sides of the pyramids. Contains fenestrated capillaries." [http://en.wikipedia.org/wiki/Straight_venules_of_kidney] synonym: "set of straight venules of kidney" EXACT [FMA:72007] synonym: "venae rectae" RELATED [http://en.wikipedia.org/wiki/Straight_venules_of_kidney] synonym: "venulae rectae" RELATED [http://en.wikipedia.org/wiki/Straight_venules_of_kidney] synonym: "venulae rectae of kidney" EXACT [FMA:72007] synonym: "venulae rectae renis" EXACT LATIN [FMA:TA] synonym: "venulae rectae renis" RELATED LATIN [http://en.wikipedia.org/wiki/Straight_venules_of_kidney] synonym: "venulae recti" RELATED [http://en.wikipedia.org/wiki/Straight_venules_of_kidney] xref: FMA:72007 xref: http://en.wikipedia.org/wiki/Straight_venules_of_kidney xref: http://www.snomedbrowser.com/Codes/Details/245983001 is_a: UBERON:0006544 ! kidney vasculature [Term] id: UBERON:0010186 name: male urethral gland namespace: uberon def: "any of the numerous small mucous-secreting glands located in the wall of the penile urethra" [MGI:anna, MP:0011794] subset: pheno_slim synonym: "gland of Littre" EXACT [] synonym: "gland of male urethra" EXACT [] synonym: "glandulae urethrales urethrae masculinae" RELATED LATIN [http://en.wikipedia.org/wiki/Urethral_gland] synonym: "Littre's gland" EXACT [FMA:21443] synonym: "male urethra gland" EXACT [] synonym: "urethral gland (male)" EXACT [FMA:21443] xref: EMAPA:29645 xref: FMA:21443 xref: http://linkedlifedata.com/resource/umls/id/C1314737 xref: http://www.snomedbrowser.com/Codes/Details/303562001 xref: NCIT:C49311 xref: UMLS:C1314737 {source="ncithesaurus:Urethral_Gland"} xref: Urethral:gland is_a: UBERON:0001338 ! urethral gland relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0010187 name: female urethral gland namespace: uberon def: "An urethral gland that is part of a female urethra." [OBOL:automatic] synonym: "female urethra gland" EXACT [] synonym: "gland of female urethra" EXACT [] synonym: "urethral gland (female)" EXACT [FMA:21444] xref: EMAPA:29653 xref: FMA:21444 xref: http://www.snomedbrowser.com/Codes/Details/279476001 is_a: UBERON:0001338 ! urethral gland relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0010390 name: lumen of urethra namespace: uberon def: "An organ cavity that is part of a urethra." [OBOL:automatic] synonym: "urethral lumen" EXACT [FMA:19709] xref: FMA:19709 xref: http://www.snomedbrowser.com/Codes/Details/279432008 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0010418 name: urethral opening namespace: uberon def: "An orifice that is part of a lower urinary tract." [OBOL:automatic] subset: pheno_slim synonym: "urethral orifice" EXACT [OBOL:automatic] xref: EMAPA:35965 xref: MA:0002867 relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: UBERON:0010531 name: metanephros induced blastemal cells namespace: uberon def: "." [http://www.embryology.ch/anglais/turinary/urinhaute03.html] synonym: "cap mesenchyme of metanephros of urinary system" RELATED [EMAPA:17645] synonym: "induced blastemal cells" EXACT [VHOG:0001241] synonym: "nephrogenic interstitium" RELATED [] synonym: "nephrogenic interstitium of nephrogenic zone" EXACT [EMAPA:17953] synonym: "peripheral blastema" RELATED [EMAPA:17953] xref: EHDAA2:0001143 xref: EHDAA:7007 xref: EHDAA:8105 xref: EMAPA:17953 xref: EMAPA:27621 xref: MA:0002998 xref: VHOG:0001241 relationship: part_of UBERON:0009871 ! nephrogenic zone property_value: UBPROP:0000012 "different versions of EMAPA have different labels for the same classes. In vHOG this is part of metanephros cortex but this leads to a cycle in basic." xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0010532 name: primitive nephron namespace: uberon def: "An epithelial tube that is fated to become a nephron." [http://orcid.org/0000-0002-6601-2165] synonym: "developing nephron" BROAD [] synonym: "future nephron" EXACT [] synonym: "presumptive nephron" EXACT [] synonym: "primitive nephron" BROAD [] is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006555 ! excretory tube property_value: UBPROP:0000012 "EHDAA2 treats this as already having a tubular structure, but in the ZFA representation this is a cluster of cells" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0010533 name: metanephros cortex namespace: uberon def: "The metanephric cortex is the outer region of the metanephros[GO]." [GO:0072214] xref: VHOG:0000714 is_a: UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0000081 {source="VHOG"} ! metanephros [Term] id: UBERON:0010534 name: primitive mesonephric nephron namespace: uberon def: "Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons." [GOC:cvs, ORCiD:0000-0002-2244-7917, ZFA:0005584] synonym: "developing mesonephric nephron" EXACT [ZFA:0005584] synonym: "primitive mesonephric nephron" EXACT [] xref: ZFA:0005584 is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0010532 ! primitive nephron [Term] id: UBERON:0010535 name: primitive metanephric nephron namespace: uberon def: "A primitive nephron that is part of a metanephros." [OBOL:automatic] synonym: "developing metanephric nephron" EXACT [] synonym: "primitive metanephric nephron" EXACT [] synonym: "primitive nephron" BROAD [EHDAA2:0001516] xref: EHDAA2:0001516 is_a: UBERON:0005106 ! metanephric tubule is_a: UBERON:0010532 ! primitive nephron [Term] id: UBERON:0010537 name: mesonephric nephron progenitor namespace: uberon def: "Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells." [ZFA:0005587] xref: ZFA:0005587 relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0011143 name: upper urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the kidney and the ureters." [FMA:45658] subset: pheno_slim xref: FMA:45658 xref: galen:UpperUrinaryTract xref: http://www.snomedbrowser.com/Codes/Details/181413006 xref: NCIT:C61107 is_a: BFO:0000040 ! material entity relationship: part_of UBERON:0001008 {source="FMA"} ! renal system [Term] id: UBERON:0011149 name: Marshall's gland namespace: uberon def: "A paired hollow organ in the genito-urinary apparatus of Raja (and probably other skates and rays) whose cavity is fluid filled." [http://www.briancoad.com/Dictionary/Complete%20Dictionary.htm] synonym: "alkaline gland" RELATED [BTO:0001661] xref: BTO:0001661 relationship: part_of UBERON:0001008 {source="BTO"} ! renal system property_value: RO:0002175 NCBITaxon:7858 [Term] id: UBERON:0011183 name: corpus spongiosum of penis namespace: uberon def: "Corpus spongiosum (also known as corpus cavernosum urethrae in older texts) is the mass of spongy tissue surrounding the male urethra within the penis." [http://en.wikipedia.org/wiki/Corpus_spongiosum_penis] synonym: "corpus cavernosum urethra" RELATED DEPRECATED [http://en.wikipedia.org/wiki/Corpus_spongiosum_penis] synonym: "corpus cavernosum urethrae" RELATED DEPRECATED [http://en.wikipedia.org/wiki/Corpus_spongiosum_penis] synonym: "corpus spongiosum" RELATED [http://en.wikipedia.org/wiki/Corpus_spongiosum_penis] synonym: "spongiose body of penis" EXACT [FMA:19617] xref: EMAPA:29850 xref: EMAPA:29856 xref: FMA:19617 xref: http://en.wikipedia.org/wiki/Corpus_spongiosum_penis xref: http://linkedlifedata.com/resource/umls/id/C1522442 xref: http://www.snomedbrowser.com/Codes/Details/279712008 xref: NCIT:C32384 xref: UMLS:C1522442 {source="ncithesaurus:Corpus_Spongiosum"} is_a: UBERON:0009010 ! periurethral tissue property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray1155.png xsd:anyURI property_value: UBPROP:0000009 "The function of the corpus spongiosum in erection is to prevent the urethra from pinching closed, thereby maintaining the urethra as a viable channel for ejaculation. To do this, the corpus spongiosum remains pliable during erection while the corpora cavernosum penis becomes engorged with blood." xsd:string {source="WP"} [Term] id: UBERON:0011199 name: prostatic utricle namespace: uberon def: "A small indentation located in the prostatic urethra, at the apex of the urethral crest, on the seminal colliculus (verumontanum), laterally flanked by openings of the ejaculatory ducts." [http://en.wikipedia.org/wiki/Prostatic_utricle] synonym: "sinus pocularis" EXACT [FMA:19702] synonym: "uterus masculinus" EXACT [FMA:19702] synonym: "uterus masculinus" RELATED LATIN [http://en.wikipedia.org/wiki/Prostatic_utricle] synonym: "utricle of prostate" EXACT [FMA:19702] synonym: "utriculus of prostate" EXACT [FMA:19702] synonym: "utriculus prostaticus" RELATED LATIN [http://en.wikipedia.org/wiki/Prostatic_utricle] synonym: "vagina masculina" EXACT LATIN [FMA:19702, http://en.wikipedia.org/wiki/Prostatic] synonym: "vagina masculina" RELATED [http://en.wikipedia.org/wiki/Prostatic_utricle] synonym: "vesicula prostatica" RELATED LATIN [http://en.wikipedia.org/wiki/Prostatic_utricle] xref: FMA:19702 xref: http://linkedlifedata.com/resource/umls/id/C0227736 xref: http://www.snomedbrowser.com/Codes/Details/197909004 xref: NCIT:C63862 xref: Prostatic:utricle xref: UMLS:C0227736 {source="ncithesaurus:Prostatic_Utricle"} relationship: part_of UBERON:0001335 {source="FMA"} ! prostatic urethra property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray1153.png xsd:anyURI property_value: IAO:0000116 "add df relations. Check mesopnephric duct" xsd:string [Term] id: UBERON:0011202 name: urachus epithelium namespace: uberon def: "An epithelium that is part of a urachus." [OBOL:automatic] xref: EHDAA2:0004725 xref: http://linkedlifedata.com/resource/umls/id/C1711256 xref: NCIT:C54210 xref: UMLS:C1711256 {source="ncithesaurus:Urachal_Epithelium"} is_a: UBERON:0006555 ! excretory tube relationship: part_of UBERON:0002068 ! urachus [Term] id: UBERON:0011203 name: urachus mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing urachus." [OBOL:automatic] xref: EHDAA2:0004726 relationship: part_of UBERON:0002068 ! urachus [Term] id: UBERON:0011379 name: male external urethral sphincter namespace: uberon def: "The external sphincter muscle of urethra (or sphincter urethrae membranaceae) surrounds the whole length of the membranous portion of the urethra, and is enclosed in the fasciæ of the urogenital diaphragm. They arch across the front of the urethra and bulbourethral glands, pass around the urethra, and behind it unite with the muscle of the opposite side, by means of a tendinous raphé." [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra] synonym: "bulboglandular" RELATED [MA:0002273] synonym: "bulboglandular muscle" RELATED [] synonym: "external urethral sphincter of male urethra" EXACT [FMA:19733] synonym: "male sphincter urethrae" EXACT [FMA:19733] synonym: "male sphincter urethrae muscle" EXACT [FMA:19733] synonym: "male urethral sphincter muscle" EXACT [FMA:19733] synonym: "musculus sphincter urethrae externus (urethra masculina)" EXACT LATIN [FMA:19733, FMA:TA] synonym: "musculus sphincter urethrae externus urethrae masculinae" EXACT LATIN [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra] synonym: "musculus sphincter urethrae membranaceae" EXACT LATIN [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra] xref: FMA:19733 xref: http://en.wikipedia.org/wiki/External_sphincter_muscle_of_male_urethra xref: http://linkedlifedata.com/resource/umls/id/C1707060 xref: MA:0002273 xref: NCIT:C52891 xref: UMLS:C1707060 {source="ncithesaurus:Bulboglandular"} is_a: UBERON:0004919 ! external urethral sphincter property_value: UBPROP:0000012 "MA includes a term bulboglandular - some sources claim this as the muscles that are associated with the bulbourethral gland, so we place this here" xsd:string {external_ontology="MA"} [Term] id: UBERON:0011380 name: female external urethral sphincter namespace: uberon def: "The external sphincter muscle of female urethra is a muscle which controls urination." [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra] synonym: "compressor urethrae" RELATED INCONSISTENT [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra] synonym: "external urethral sphincter of female urethra" EXACT [] synonym: "musculus sphincter urethrae externus (urethra feminina)" EXACT LATIN [FMA:19778, FMA:TA] synonym: "musculus sphincter urethrae externus urethrae femininae" EXACT LATIN [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra] synonym: "outer muscle layer of female urethra" EXACT [FMA:19778] synonym: "rhabdosphincter of female urethra" EXACT [FMA:19778] synonym: "sphincter urethrovaginalis" RELATED DEPRECATED [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra] synonym: "striated muscle layer of female urethra" EXACT [FMA:19778] synonym: "urethrovaginal sphincter" RELATED DEPRECATED [http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra] xref: FMA:19778 xref: http://en.wikipedia.org/wiki/External_sphincter_muscle_of_female_urethra is_a: UBERON:0004919 ! external urethral sphincter [Term] id: UBERON:0011574 name: mesonephric duct lumen namespace: uberon def: "A tube lumen that is part of a mesonephric duct." [OBOL:automatic] synonym: "cavity of nephric duct" RELATED [] synonym: "nephric duct lumen" EXACT [EHDAA2:0001244] xref: EHDAA2:0001244 relationship: part_of UBERON:0003074 ! mesonephric duct [Term] id: UBERON:0011830 name: duct of lesser vestibular gland namespace: uberon def: "A duct that is part of a minor vestibular gland." [OBOL:automatic] synonym: "lesser vestibular gland duct" EXACT [FMA:20094] xref: FMA:20094 relationship: part_of UBERON:0000461 ! minor vestibular gland [Term] id: UBERON:0011947 name: ureter luminal urothelium namespace: uberon def: "A luminal layer of epithelium that is part of a ureter." [OBOL:automatic] subset: pheno_slim xref: EMAPA:37779 {source="MA:th"} xref: MA:0002656 relationship: part_of UBERON:0001254 ! urothelium of ureter [Term] id: UBERON:0011948 name: ureter subluminal urothelium namespace: uberon xref: EMAPA:37780 {source="MA:th"} xref: MA:0002657 relationship: part_of UBERON:0001254 ! urothelium of ureter [Term] id: UBERON:0012238 name: ureteric bud trunk namespace: uberon def: "ureteric bud cells that elongate to form a rigid structure (stalk) consisting of polarized epithelial cells without branching; the stalks differentiate into the collecting system of the mature kidney, while the tip cells interact with the adjacent cells of the metanephric mesenchyme, inducing their conversion into nephrons." [MP:0011761] subset: pheno_slim synonym: "ureteric bud stalk" RELATED [MP:0011761] synonym: "ureteric stalk" RELATED [EMAPA:27608] synonym: "ureteric trunk" RELATED [EMAPA:27608] xref: EMAPA:27608 xref: EMAPA:27697 is_a: UBERON:0000083 ! mesonephric tubule relationship: part_of UBERON:0000084 ! ureteric bud [Term] id: UBERON:0012239 name: urinary bladder vasculature namespace: uberon def: "network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP]" [MP:MP] subset: pheno_slim synonym: "bladder vasculature" EXACT [] synonym: "blood vessel of bladder" RELATED [EMAPA:28679] synonym: "blood vessels of bladder" EXACT [EMAPA:28679] synonym: "set of urinary bladder blood vessels" EXACT [] xref: EMAPA:28679 relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: UBERON:0012240 name: urethral meatus namespace: uberon def: "external opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]." [http://en.wikipedia.org/wiki/Urinary_meatus, MP:MP] subset: pheno_slim synonym: "external meatus of urethra" EXACT [FMA:19650] synonym: "external urethral orifice" EXACT [FMA:19650] synonym: "external urethral ostium" EXACT [FMA:19650] synonym: "external urinary meatus" EXACT [FMA:19650] synonym: "meatus urinarius" EXACT LATIN [] synonym: "orificium urethrae externum" EXACT LATIN [] synonym: "orificium urethræ externum" EXACT LATIN [] synonym: "urethral meatus" EXACT [FMA:19650] synonym: "urinary meatus" RELATED [] xref: EMAPA:37977 {source="MA:th"} xref: FMA:19650 xref: http://www.snomedbrowser.com/Codes/Details/181424008 xref: Urinary:meatus is_a: UBERON:0010418 ! urethral opening relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012241 name: male urethral meatus namespace: uberon def: "A urethral meatus that is part of a male urethra[Automatically generated definition]." [http://en.wikipedia.org/wiki/External_urethral_orifice_(male), OBOL:automatic] synonym: "distal urethral opening of male" RELATED [EMAPA:36434] synonym: "external orifice of male urethra" EXACT [FMA:85265] synonym: "external urethral orifice (male)" EXACT [FMA:85265] synonym: "male urethra ostium" EXACT [MA:0002642] synonym: "ostium urethrae externum (urethra masculina)" EXACT LATIN [FMA:TA] synonym: "urethral meatus of penile urethra" EXACT [EMAPA:36434] synonym: "urethral opening of penile urethra" RELATED [EMAPA:36434] xref: EMAPA:36434 xref: FMA:85265 xref: http://en.wikipedia.org/wiki/External_urethral_orifice_(male) xref: http://www.snomedbrowser.com/Codes/Details/279478000 xref: MA:0002642 is_a: UBERON:0012240 ! urethral meatus relationship: part_of UBERON:0001333 ! male urethra property_value: UBPROP:0000001 "The external urethral orifice is the external opening or meatus of the urethra, normally placed at the tip of glans penis; it presents as a vertical slit, possibly bounded on either side by two small labia-like projections, In some cases the slit may be more rounded. This occurs naturally in some males and may also be a side effect of excess skin removal during circumcision. Congenital misplacement of the urethral orifice is called hypospadias when it is located in the underside (ventral aspect) of the penis, and epispadias when located in the dorsum (upper aspect). Improper shaping of the meatus can result in meatal stenosis." xsd:string {source="http://en.wikipedia.org/wiki/External_urethral_orifice_(male)"} [Term] id: UBERON:0012242 name: internal urethral orifice namespace: uberon def: "the usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone" [MGI:anna, MP:0011782] subset: pheno_slim synonym: "internal meatus of urethra" EXACT [FMA:85263] synonym: "internal urethral orifice of urinary bladder" EXACT [FMA:85263] synonym: "internal urethral ostium" EXACT [FMA:85263] synonym: "internal urethral ostium" RELATED [MP:0011782] synonym: "internal urinary meatus" RELATED [MP:0011782] synonym: "orificium urethrae internum" EXACT LATIN [MP:0011782] synonym: "ostium orificium internum" EXACT LATIN [] synonym: "ostium urethrae internum" EXACT LATIN [http://en.wikipedia.org/wiki/Internal_urethral_orifice] synonym: "vesicourethral orifice" EXACT [FMA:85263] xref: FMA:85263 xref: http://en.wikipedia.org/wiki/Internal_urethral_orifice xref: http://www.snomedbrowser.com/Codes/Details/362228001 is_a: UBERON:0010418 ! urethral opening relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012294 name: navicular fossa of spongiose part of urethra namespace: uberon def: "The dilated terminal portion of the male spongy urethra located in the glans penis right before the external urethral orifice, also referred to as the most distal pendulous urethra; it is lined by stratified squamous, non-keratinizing epithelium; during development, the glans of the penis is initially solid but cannulates to give rise to the navicular fossa." [http://en.wikipedia.org/wiki/Navicular_fossa_of_male_urethra, MP:0011838, MP:anna] subset: pheno_slim synonym: "fossa navicularis of urethra" EXACT [] synonym: "fossa navicularis urethrae" EXACT [FMA:TA] synonym: "fossa navicularis urethrae" RELATED [http://en.wikipedia.org/wiki/Navicular_fossa_of_male_urethra] synonym: "fossa navicularis urethrae (pars spongiosa, urethra masculina)" EXACT [FMA:19722] synonym: "navicular fossa" EXACT [FMA:19722] synonym: "navicular fossa of urethra" EXACT [] xref: FMA:19722 xref: http://en.wikipedia.org/wiki/Navicular_fossa_of_male_urethra xref: http://www.snomedbrowser.com/Codes/Details/362233002 relationship: part_of UBERON:0001337 ! spongiose part of urethra [Term] id: UBERON:0012295 name: Guérin's valve namespace: uberon def: "An inconstant fold or valve of mucous membrane sometimes found in the root or upper wall of the navicular fossa of the urethra" [http://www.drugs.com/dict/valve-of-navicular-fossa.html, MP:0011839, MP:anna] subset: pheno_slim synonym: "Guerin's valve" EXACT [] synonym: "Guérin's fold" EXACT [http://www.drugs.com/dict/valve-of-navicular-fossa.html] synonym: "Guérin's valvule" EXACT [MP:anna] synonym: "urethral valve of Guérin" EXACT [MP:anna] synonym: "valve of fossa navicularis of urethra" EXACT [] synonym: "valvula fossae navicularis" EXACT LATIN [MP:anna] xref: FMA:19781 xref: http://www.snomedbrowser.com/Codes/Details/367737008 relationship: part_of UBERON:0012294 ! navicular fossa of spongiose part of urethra relationship: part_of UBERON:0012299 ! mucosa of urethra [Term] id: UBERON:0012296 name: urethral crest namespace: uberon def: "A longitudinal mucosal fold in the dorsal wall of the urethra[MP]" [http://en.wikipedia.org/wiki/Urethral_crest, MP:0011840, MP:anna] subset: pheno_slim synonym: "crista of urethra" EXACT [] synonym: "crista urethralis" EXACT LATIN [MP:anna] synonym: "urethral crista" EXACT [] xref: FMA:19718 xref: http://www.snomedbrowser.com/Codes/Details/362231000 xref: Urethral:crest relationship: part_of UBERON:0012299 ! mucosa of urethra property_value: UBPROP:0000012 "in the FMA this is part of the prostatic urethra - but this leads to inconsistencies as 'urethral crest' in sex-neutral, with male and female subtypes" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0012297 name: male urethral crest namespace: uberon def: "narrow longitudinal fold of mucosa on the posterior wall of the male urethra, extending from the uvula of the bladder through the prostatic urethra; when distended, it may serve to prevent the passage of the semen backward into the bladder; on either side of the male urethral crest is a slightly depressed fossa, the prostatic sinus, the floor of which is perforated by the orifices of the prostatic ducts from the lateral lobes of the prostate; the ducts of the middle lobe open behind the crest; at the forepart of the crest, below its summit, is a median elevation, the colliculus seminalis, upon or within the margins of which are the orifices of the prostatic utricle and the slit-like openings of the ejaculatory ducts[MP]" [MP:0011841, MP:anna] subset: pheno_slim synonym: "crista phallica" EXACT LATIN [MP:anna] synonym: "crista urethralis masculinae" EXACT LATIN [MP:anna] synonym: "urethral crest (male)" EXACT [FMA:85270] synonym: "urethral crest of male" EXACT [MP:anna] xref: FMA:85270 xref: http://www.snomedbrowser.com/Codes/Details/279470007 is_a: UBERON:0012296 ! urethral crest relationship: part_of UBERON:0005015 {source="cjm"} ! mucosa of prostatic urethra [Term] id: UBERON:0012298 name: female urethral crest namespace: uberon def: "The conspicuous longitudinal fold of mucosa on the posterior wall of the female urethra[MP]" [MP:0011842, MP:anna] subset: pheno_slim synonym: "crista urethralis femininae" EXACT LATIN [MP:anna] synonym: "urethral crest (female)" EXACT [FMA:85271] synonym: "urethral crest of female" EXACT [MP:anna] xref: FMA:85271 xref: http://www.snomedbrowser.com/Codes/Details/279471006 is_a: UBERON:0012296 ! urethral crest relationship: part_of UBERON:0005014 {source="cjm"} ! mucosa of female urethra [Term] id: UBERON:0012299 name: mucosa of urethra namespace: uberon def: "A mucosa that is part of a urethra." [OBOL:automatic] synonym: "mucous membrane of urethra" EXACT [FMA:76904] synonym: "tunica mucosa urethrae" EXACT [FMA:TA] synonym: "urethral mucosa" EXACT [FMA:76904] xref: EMAPA:37912 {source="MA:th"} xref: FMA:76904 xref: http://www.snomedbrowser.com/Codes/Details/362229009 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012301 name: female membranous urethra namespace: uberon def: "A membranous urethra of male or female that is part of a female urethra." [OBOL:automatic] xref: EMAPA:37537 {source="MA:th"} xref: MA:0002638 is_a: UBERON:0001336 ! membranous urethra of male or female relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0012302 name: male membranous urethra namespace: uberon def: "the shortest, least dilatable, and, with the exception of the external orifice, the narrowest part of the male urethral canal located in the deep perineal pouch and lined by pseudostratified columnar epithelium; it extends downward and forward, with a slight anterior concavity, between the apex of the prostate and the bulb of the urethra, perforating the urogenital diaphragm below and behind the pubic symphysis; the membranous portion of the urethra is completely surrounded by the fibers of the sphincter urethrae membranaceae; on either side near its termination are the bulbourethral glands" [MGI:anna, MP:0011778] subset: pheno_slim synonym: "intermediate part of male urethra" RELATED [http://en.wikipedia.org/wiki/Membranous_urethra] synonym: "membranous urethra" BROAD INCONSISTENT [FMA:19674] synonym: "pars intermedia urethrae masculinae" RELATED LATIN [http://en.wikipedia.org/wiki/Membranous_urethra] synonym: "pars membranacea urethrae masculinae" RELATED LATIN [http://en.wikipedia.org/wiki/Membranous_urethra] xref: FMA:19674 xref: http://linkedlifedata.com/resource/umls/id/C0458453 xref: http://www.snomedbrowser.com/Codes/Details/263343009 xref: MA:0002641 xref: Membranous:urethra xref: NCIT:C33091 xref: UMLS:C0458453 {source="ncithesaurus:Membranous_Urethra"} is_a: UBERON:0001336 ! membranous urethra of male or female relationship: part_of UBERON:0001333 ! male urethra property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray1142.png xsd:anyURI [Term] id: UBERON:0012303 name: ureteral orifice namespace: uberon def: "The slit-like opening of either ureter into the bladder; normally, the two ureteral orifices are placed at the posterolateral angles of the urinary bladder trigone while the internal urethral orifice is placed at its anteroinferior angle (apex); wide gaping usually indicates vesicoureteral reflux" [http://en.wikipedia.org/wiki/Orifice_of_ureter, MP:0011783] subset: pheno_slim synonym: "Mercier's bar" EXACT [FMA:77047] synonym: "orifice of ureter" EXACT [FMA:77047] synonym: "orificium ureteris" EXACT LATIN [MP:0011783] synonym: "ostium ureteris" EXACT LATIN [MP:0011783] synonym: "ostium ureteris" EXACT [FMA:TA] synonym: "ureteral meatus" EXACT [MP:0011783] synonym: "ureteral opening" EXACT [MP:0011783] synonym: "ureteric orifice" EXACT [FMA:77047] synonym: "ureteric orifice" EXACT [MP:0011783] synonym: "ureteric ostium" EXACT [FMA:77047] synonym: "ureterovesical orifice" EXACT [FMA:77047] synonym: "ureterovesical orifice" EXACT [MP:0011783] xref: FMA:77047 xref: http://en.wikipedia.org/wiki/Orifice_of_ureter xref: http://www.snomedbrowser.com/Codes/Details/181415004 xref: NCIT:C12337 is_a: UBERON:0010418 ! urethral opening relationship: part_of UBERON:0006082 ! fundus of urinary bladder relationship: part_of UBERON:0009973 ! ureterovesical junction property_value: IAO:0000116 "TODO - add relationship to junction" xsd:string [Term] id: UBERON:0012351 name: urachal lumen namespace: uberon def: "A anatomical space that is enclosed by a urachus." [OBOL:automatic] synonym: "urachus lumen" EXACT [] relationship: part_of UBERON:0002068 ! urachus [Term] id: UBERON:0012352 name: mesangial matrix namespace: uberon def: "Extracellular matrix secreted by intraglomerular mesangial cells" [MP:0011338] subset: pheno_slim synonym: "extracellular mesangial matrix" EXACT [MP:0011338] xref: EMAPA:37907 {source="MA:th"} relationship: part_of UBERON:0002319 ! mesangium [Term] id: UBERON:0012378 name: muscle layer of urinary bladder namespace: uberon def: "A muscular coat that is part of a urinary bladder." [OBOL:automatic] synonym: "bladder muscular coat" EXACT [] synonym: "muscle layer of urinary bladder" EXACT [FMA:15930] synonym: "muscular coat of bladder" EXACT [FMA:15930] synonym: "muscular coat of urinary bladder" EXACT [FMA:15930] synonym: "muscular layer of bladder" EXACT [FMA:15930] synonym: "muscular layer of urinary bladder" EXACT [FMA:15930] synonym: "tunica musculari vesicae" EXACT [FMA:TA] synonym: "tunica muscularis (vesica urinaria)" EXACT [FMA:TA] xref: FMA:15930 xref: http://linkedlifedata.com/resource/umls/id/C1288327 xref: NCIT:C32206 xref: UMLS:C1288327 {source="ncithesaurus:Bladder_Muscular_Coat"} relationship: part_of UBERON:0001256 {source="FMA"} ! wall of urinary bladder [Term] id: UBERON:0012428 name: proximal convoluted tubule brush border namespace: uberon def: "A brush border layer that is part of a proximal tubule in the kidney." [http://en.wikipedia.org/wiki/Microvillus#Function, http://orcid.org/0000-0002-6601-2165] synonym: "kidney brush border layer" BROAD [] synonym: "proximal tubule brush border layer" BROAD [] relationship: part_of UBERON:0001287 ! proximal convoluted tubule property_value: UBPROP:0000009 "the microvilli in this layer can act as mechanosensors. They sense the fluid flow in the tubule lumen and convert this information via biochemical responses into reabsorption" xsd:string [Term] id: UBERON:0012441 name: endothelium of peritubular capillary namespace: uberon def: "A endothelium that is part of a peritubular capillary." [OBOL:automatic] synonym: "peritubular capillary endothelium" EXACT [] synonym: "peritubular endothelium" BROAD [] is_a: UBERON:0004819 ! kidney epithelium relationship: part_of UBERON:0005272 ! peritubular capillary [Term] id: UBERON:0013244 name: vaginal plate namespace: uberon def: "The vaginal plate is a precursor to the inferior portion of the vagina. They form from sinovaginal bulbs." [http://en.wikipedia.org/wiki/Vaginal_plate] xref: http://linkedlifedata.com/resource/umls/id/C1519928 xref: NCIT:C34325 xref: UMLS:C1519928 {source="ncithesaurus:Vaginal_Plate"} xref: Vaginal:plate relationship: part_of UBERON:0000164 ! primitive urogenital sinus [Term] id: UBERON:0013245 name: sinovaginal bulb namespace: uberon def: "solid evaginations of the UG sinus that develops into a vaginal plate that which will will eventually canalize to form the inferior portion of the vagina." [https://orcid.org/0000-0002-6601-2165] xref: http://linkedlifedata.com/resource/umls/id/C1519330 xref: NCIT:C34297 xref: UMLS:C1519330 {source="ncithesaurus:Sinovaginal_Bulb"} relationship: part_of UBERON:0000164 ! primitive urogenital sinus [Term] id: UBERON:0014388 name: kidney collecting duct epithelium namespace: uberon def: "The simple cuboidal epithelium lining the lumen of kidney collecting ducts." [MGI:anna, MP:0011843] subset: pheno_slim synonym: "collecting duct of renal tubule epithelium" EXACT [] synonym: "epithelium of collecting duct of renal tubule" EXACT [] synonym: "epithelium of renal collecting tubule" EXACT [] xref: EMAPA:37885 {source="MA:th"} is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: UBPROP:0000008 "In mouse, the mature and differentiated CD epithelium comprises two unique cells types with principal cells responsible for vasopressin-regulated water reabsorption, and intercalated cells regulating acid-base homeostasis; injury to the epithelium is believed to cause epithelial cells to acquire mesenchymal characteristics via epithelial-mesenchymal transition (EMT), a process through which tubular epithelial cells may transform into interstitial fibroblasts and promote renal fibrosis" xsd:string [Term] id: UBERON:0014401 name: renal venous blood vessel namespace: uberon def: "Any member of the network of tubes that return blood from the renal tissues to the systemic circulation." [MGI:csmith] subset: pheno_slim synonym: "kidney venous blood vessel" EXACT [MA:0002591] synonym: "kidney venous system" RELATED [EMAPA:31450] synonym: "venous blood vessel of kidney" EXACT [] xref: EMAPA:31450 xref: MA:0002591 is_a: UBERON:0003517 ! kidney blood vessel property_value: UBPROP:0000012 "we follow MA and MP in distinguishing the venous blood vessel from the vein. The kidney cortex vein is not considered a renal vein, nor is the vasa recta" xsd:string {external_ontology="MA"} [Term] id: UBERON:0014464 name: renal fat pad namespace: uberon def: "Encapsulated adipose tissue associated with the kidney" [MP:0008902] subset: pheno_slim synonym: "perirenal fat pad" RELATED [MP:0008902] relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0014782 name: allantois of embryonic urinary system namespace: uberon comment: remnant of allantois in embryo synonym: "allantois" RELATED [EHDAA2:0000113] xref: EHDAA2:0000113 xref: EMAPA:28547 relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system [Term] id: UBERON:0015418 name: urethra mesenchymal layer namespace: uberon def: "A mesenchyme that is part of a urethra." [OBOL:automatic] xref: EMAPA:37786 {source="MA:th"} xref: MA:0002648 relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0015420 name: ureteral valve namespace: uberon def: "A valve that is part of a ureter." [OBOL:automatic] synonym: "ureteral valve" EXACT [MA:0002658] synonym: "valve or ureter" EXACT [] xref: EMAPA:37781 {source="MA:th"} xref: MA:0002658 relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0015777 name: transitional epithelium of prostatic urethra namespace: uberon xref: FMA:74267 is_a: UBERON:0004787 ! urethra urothelium is_a: UBERON:0016510 ! epithelium of male urethra relationship: part_of UBERON:0001335 ! prostatic urethra [Term] id: UBERON:0016500 name: muscularis mucosa of fundus of urinary bladder namespace: uberon def: "A muscularis mucosa that is part of a fundus of urinary bladder." [OBOL:automatic] xref: EMAPA:28625 is_a: UBERON:0006912 ! urinary bladder muscularis mucosa relationship: part_of UBERON:0006082 ! fundus of urinary bladder [Term] id: UBERON:0016505 name: Mullerian tubercle namespace: uberon def: "An elevation on the wall of the embryonic urogenital sinus where the Müllerian ducts enter." [http://www.merriam-webster.com/medical/m%C3%BCllerian%20tubercle] synonym: "Muellerian tubercle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "mullerian tubercle" EXACT [FMA:72175] synonym: "Müllerian tubercle" EXACT [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:18328 xref: FMA:72175 xref: MA:0003239 relationship: part_of UBERON:0000164 ! primitive urogenital sinus [Term] id: UBERON:0016510 name: epithelium of male urethra namespace: uberon def: "A epithelium that is part of a male urethra." [OBOL:automatic] synonym: "male urethral epithelium" EXACT [FMA:FMA] synonym: "urethral epithelium of male" EXACT [EMAPA:30467] xref: EMAPA:30467 xref: FMA:19684 is_a: UBERON:0002325 ! epithelium of urethra relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0016515 name: muscular layer of prostatic urethra namespace: uberon def: "A muscular coat that is part of a prostatic urethra." [OBOL:automatic] synonym: "muscle layer of prostatic part of urethra" EXACT [FMA:FMA] synonym: "muscle layer of prostatic urethra" EXACT [EMAPA:30956] synonym: "muscle layer of prostatic urethra" EXACT [FMA:FMA] synonym: "muscular coat of prostatic urethra" EXACT [FMA:FMA] xref: EMAPA:30956 xref: FMA:19699 relationship: part_of UBERON:0001335 ! prostatic urethra [Term] id: UBERON:0016516 name: lamina propria of prostatic urethra namespace: uberon def: "A lamina propria that is part of a prostatic urethra." [OBOL:automatic] synonym: "lamina propria of prostatic part of urethra" EXACT [FMA:FMA] synonym: "lamina propria of prostatic urethra" EXACT [EMAPA:32303] xref: EMAPA:32303 xref: FMA:19693 is_a: UBERON:0002326 ! lamina propria of urethra relationship: part_of UBERON:0001335 ! prostatic urethra [Term] id: UBERON:0016520 name: epithelium of female urethra namespace: uberon def: "A epithelium that is part of a female urethra." [OBOL:automatic] synonym: "female urethral epithelium" EXACT [FMA:FMA] synonym: "urethral epithelium of female" EXACT [EMAPA:30470] xref: EMAPA:30470 xref: FMA:19774 is_a: UBERON:0002325 ! epithelium of urethra relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0016524 name: muscle layer of spongiose part of urethra namespace: uberon def: "A muscular coat that is part of a spongiose part of urethra." [OBOL:automatic] synonym: "muscle layer of penile urethra" EXACT [FMA:FMA] synonym: "muscle layer of penile urethra" EXACT [EMAPA:30950] synonym: "muscle layer of spongy urethra" EXACT [FMA:FMA] synonym: "muscular coat of spongy urethra" EXACT [FMA:FMA] synonym: "muscular layer of spongy urethra" EXACT [FMA:FMA] synonym: "tunica muscularis urethrae spongiosa" EXACT LATIN [FMA:19701, FMA:TA] xref: EMAPA:30950 xref: FMA:19701 relationship: part_of UBERON:0001337 ! spongiose part of urethra [Term] id: UBERON:0018113 name: left kidney interstitium namespace: uberon def: "A kidney interstitium that is part of a left kidney." [OBOL:automatic] synonym: "left renal stroma" EXACT [FMA:74271] synonym: "stroma of left kidney" EXACT [FMA:74271] xref: FMA:74271 is_a: UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0004538 ! left kidney [Term] id: UBERON:0018114 name: right kidney interstitium namespace: uberon def: "A kidney interstitium that is part of a right kidney." [OBOL:automatic] synonym: "right renal stroma" EXACT [FMA:74270] synonym: "stroma of right kidney" EXACT [FMA:74270] xref: FMA:74270 is_a: UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0004539 ! right kidney [Term] id: UBERON:0018115 name: left renal pelvis namespace: uberon def: "A renal pelvis that is part of a left ureter." [OBOL:automatic] synonym: "pelvis of left ureter" EXACT [FMA:15579] synonym: "renal pelvis of left kidney" EXACT [FMA:15579] xref: FMA:15579 xref: http://www.snomedbrowser.com/Codes/Details/243436005 is_a: UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001223 ! left ureter [Term] id: UBERON:0018116 name: right renal pelvis namespace: uberon def: "A renal pelvis that is part of a right ureter." [OBOL:automatic] synonym: "pelvis of right kidney" EXACT [FMA:15578] synonym: "pelvis of right ureter" EXACT [FMA:15578] xref: FMA:15578 xref: http://www.snomedbrowser.com/Codes/Details/243419002 is_a: UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001222 ! right ureter [Term] id: UBERON:0018117 name: left renal cortex interstitium namespace: uberon def: "A renal cortex interstitium that is part of a left kidney." [OBOL:automatic] synonym: "cortical interstitial tissue of left kidney" EXACT [] is_a: UBERON:0005270 ! renal cortex interstitium is_a: UBERON:0018113 ! left kidney interstitium [Term] id: UBERON:0018118 name: right renal cortex interstitium namespace: uberon def: "A renal cortex interstitium that is part of a right kidney." [OBOL:automatic] synonym: "cortical interstitial tissue of right kidney" EXACT [] is_a: UBERON:0005270 ! renal cortex interstitium is_a: UBERON:0018114 ! right kidney interstitium [Term] id: UBERON:0018119 name: left renal medulla interstitium namespace: uberon def: "A renal medulla interstitium that is part of a left kidney." [OBOL:automatic] synonym: "medullary interstitial tissue of left kidney" EXACT [] is_a: UBERON:0005211 ! renal medulla interstitium is_a: UBERON:0018113 ! left kidney interstitium [Term] id: UBERON:0018120 name: right renal medulla interstitium namespace: uberon def: "A renal medulla interstitium that is part of a right kidney." [OBOL:automatic] synonym: "medullary interstitial tissue of right kidney" EXACT [] is_a: UBERON:0005211 ! renal medulla interstitium is_a: UBERON:0018114 ! right kidney interstitium [Term] id: UBERON:0034770 name: bulbourethral gland epithelium namespace: uberon synonym: "epithelium of bulbourethral gland" EXACT [] synonym: "epithelium of bulbourethral gland of male" EXACT [EMAPA:29790] xref: EMAPA:29790 is_a: UBERON:0016510 ! epithelium of male urethra relationship: part_of UBERON:0002366 ! bulbo-urethral gland [Term] id: UBERON:0034884 name: juxtaglomerular arteriole namespace: uberon xref: EMAPA:27991 is_a: UBERON:0003644 ! kidney arterial blood vessel property_value: IAO:0000116 "compare with afferent arteriole" xsd:string [Term] id: UBERON:0034996 name: outer renal medulla loop of Henle namespace: uberon synonym: "loop of Henle, outer medullary portion" EXACT [EMAPA:28322] xref: EMAPA:28322 is_a: UBERON:0034997 ! renal medulla loop of Henle relationship: part_of UBERON:0001293 ! outer medulla of kidney [Term] id: UBERON:0034997 name: renal medulla loop of Henle namespace: uberon synonym: "loop of Henle of renal medulla" EXACT [EMAPA:35460] synonym: "loop of Henle, medullary portion" EXACT [] xref: EMAPA:35460 is_a: UBERON:0001288 ! loop of Henle relationship: part_of UBERON:0000362 ! renal medulla [Term] id: UBERON:0035368 name: anterior surface of kidney namespace: uberon def: "The aspect of the kidney facing the abdominal cavity." [ncithesaurus:Anterior_Surface_of_the_Kidney] synonym: "facies anterior (Ren)" EXACT [FMA:15589] synonym: "facies anterior renis" EXACT LATIN [FMA:15589, FMA:TA] xref: FMA:15589 xref: http://linkedlifedata.com/resource/umls/id/C0227609 xref: http://www.snomedbrowser.com/Codes/Details/279375001 xref: NCIT:C32107 relationship: part_of UBERON:0002113 {source="ncithesaurus"} ! kidney [Term] id: UBERON:0035471 name: posterior surface of kidney namespace: uberon synonym: "facies posterior (Ren)" EXACT [FMA:15590] synonym: "facies posterior renis" EXACT LATIN [FMA:15590, FMA:TA] xref: FMA:15590 xref: http://linkedlifedata.com/resource/umls/id/C0227610 xref: http://www.snomedbrowser.com/Codes/Details/279376000 xref: NCIT:C32895 relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0035758 name: peritubular capillary plexus of kidney namespace: uberon synonym: "peritubular capillary network of kidney" EXACT [FMA:272218] synonym: "peritubular capillary plexus" EXACT [FMA:272218] xref: FMA:272218 xref: http://www.snomedbrowser.com/Codes/Details/36447007 is_a: UBERON:0035762 ! capillary network of kidney [Term] id: UBERON:0035762 name: capillary network of kidney namespace: uberon synonym: "capillary plexus of kidney" EXACT [FMA:280922] xref: FMA:280922 is_a: UBERON:0006544 ! kidney vasculature [Term] id: UBERON:0036295 name: renal pelvis/ureter namespace: uberon def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419] synonym: "renal pelvis and ureter" EXACT [] synonym: "renal pelvis plus ureter" EXACT [] xref: NCIT:C54419 relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract [Term] id: UBERON:0036375 name: wall of right ureter namespace: uberon synonym: "right ureteral wall" EXACT [FMA:15889] xref: FMA:15889 is_a: UBERON:0009916 {source="FMA"} ! wall of ureter relationship: part_of UBERON:0001222 {source="FMA"} ! right ureter [Term] id: UBERON:0036376 name: wall of left ureter namespace: uberon synonym: "left ureteral wall" EXACT [FMA:15890] xref: FMA:15890 is_a: UBERON:0009916 {source="FMA"} ! wall of ureter relationship: part_of UBERON:0001223 {source="FMA"} ! left ureter [Term] id: UBERON:0036521 name: wall of urethra namespace: uberon synonym: "urethral wall" EXACT [FMA:19779] xref: FMA:19779 relationship: part_of UBERON:0000057 {source="FMA"} ! urethra [Term] id: UBERON:0037447 name: wall of male urethra namespace: uberon synonym: "male urethral wall" EXACT [FMA:19676] xref: FMA:19676 is_a: UBERON:0036521 {source="FMA"} ! wall of urethra relationship: part_of UBERON:0001333 {source="FMA"} ! male urethra [Term] id: UBERON:0037455 name: wall of female urethra namespace: uberon synonym: "female urethral wall" EXACT [FMA:19780] xref: FMA:19780 is_a: UBERON:0036521 {source="FMA"} ! wall of urethra relationship: part_of UBERON:0001334 {source="FMA"} ! female urethra [Term] id: UBERON:2001055 name: pronephric duct opening namespace: uberon/phenoscape-anatomy xref: ZFA:0001055 relationship: part_of UBERON:0003060 ! pronephric duct property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:2001200 name: corpuscles of Stannius namespace: uberon/phenoscape-anatomy def: "Islands of eosinic cells found on the lateroventral surface of the kidney. Function is thought to be that of the parathyroid gland in other vertebrates, which are lacking in fishes. These cells secrete hypocalcin (teleocalcin) to regulate calcium metabolism." [ZFIN:curator] xref: ZFA:0001200 relationship: part_of UBERON:0000080 ! mesonephros property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:2001293 name: posterior kidney namespace: uberon/phenoscape-anatomy xref: ZFA:0001293 relationship: part_of UBERON:0000080 ! mesonephros property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:2002225 name: posterior pronephric duct namespace: uberon/phenoscape-anatomy synonym: "posterior pronephric ducts" EXACT PLURAL [TAO:0002225] xref: ZFA:0001623 is_a: UBERON:0006553 ! renal duct relationship: part_of UBERON:0003060 ! pronephric duct property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:2005292 name: distal late tubule namespace: uberon/phenoscape-anatomy def: "Portion of the renal tubule which is just posterior to the distal early tubule." [ZFIN:curator] xref: ZFA:0005292 is_a: UBERON:0006553 ! renal duct relationship: part_of UBERON:0001231 ! nephron tubule property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:2005311 name: pronephric glomerular capsule epithelium namespace: uberon/phenoscape-anatomy def: "Simple squamous epithelium that lines the capsule of the pronephric glomerulus." [ZFIN:curator] synonym: "pronephric parietal epithelial layer" EXACT [TAO:0005311] xref: ZFA:0005311 is_a: UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0001230 ! glomerular capsule property_value: provenance_notes "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: teleost_anatomy_curators [Term] id: UBERON:3010392 name: mesonephric early proximal tubule namespace: uberon/phenoscape-anatomy is_a: UBERON:0006553 ! renal duct relationship: part_of UBERON:0000083 ! mesonephric tubule property_value: provenance_notes "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: amphibian_anatomy_curators [Term] id: UBERON:3010393 name: mesonephric late distal segment namespace: uberon/phenoscape-anatomy def: "The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons. [Xenbase]" [] synonym: "DT1" EXACT [UBERON:3010393] relationship: part_of UBERON:0000083 ! mesonephric tubule property_value: provenance_notes "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: amphibian_anatomy_curators [Term] id: UBERON:3010394 name: mesonephric late proximal tubule namespace: uberon/phenoscape-anatomy synonym: "late proximal segment" EXACT [UBERON:3010394] synonym: "opisthonephros" RELATED [UBERON:3010394] synonym: "proximal straight segment" RELATED [UBERON:3010394] synonym: "proximal tubule 3" EXACT [UBERON:3010394] synonym: "PT3" EXACT [UBERON:3010394] is_a: UBERON:0006553 ! renal duct relationship: part_of UBERON:0000083 ! mesonephric tubule property_value: provenance_notes "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: amphibian_anatomy_curators [Term] id: UBERON:3011120 name: early proximal tubule namespace: uberon/phenoscape-anatomy synonym: "PT2" EXACT [UBERON:3011120] relationship: part_of UBERON:0005309 ! pronephric nephron property_value: provenance_notes "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: amphibian_anatomy_curators creation_date: 2011-04-20T05:19:55Z [Term] id: UBERON:3011121 name: late distal segment namespace: uberon/phenoscape-anatomy relationship: part_of UBERON:0005309 ! pronephric nephron property_value: provenance_notes "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string created_by: amphibian_anatomy_curators creation_date: 2011-04-20T05:21:45Z [Term] id: http://owltools.org/Q [Typedef] id: part_of name: part of name: part_of namespace: external namespace: protein namespace: quality namespace: uberon def: "a core relation that holds between a part and its whole" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000050 property_value: IAO:0000111 "is part of" xsd:string property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string property_value: IAO:0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string property_value: IAO:0000118 "part_of" xsd:string property_value: RO:0001900 RO:0001901 property_value: RO:0040042 BFO:0000002 property_value: RO:0040042 BFO:0000003 property_value: RO:0040042 BFO:0000004 property_value: RO:0040042 BFO:0000017 property_value: RO:0040042 BFO:0000019 property_value: RO:0040042 BFO:0000020 property_value: RO:0040042 BFO:0000031 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf property_value: seeAlso http://www.obofoundry.org/ro/#OBO_REL:part_of xsd:string is_transitive: true