pathological entity
type: Class
IAO_0000115: Pathological structure or process
has OBO namespace: mouse_pathology.ontology
id: MPATH:0

cell and tissue damage
type: Class
subclass of: pathological anatomical entity
IAO_0000115: The sum of morphological and functional disturbances induced by cell and tissue damage, either from intrinsic gene dysfunction or as a result of external factors.
has OBO namespace: mouse_pathology.ontology
id: MPATH:1

circulatory disorder
type: Class
subclass of: pathological anatomical entity
IAO_0000115: Lesions leading to or consequent on failure of, or atypical movement of, blood throughout the body.
has OBO namespace: mouse_pathology.ontology
id: MPATH:105

hemorrhage and non-specified extravasation
type: Class
subclass of: circulatory disorder
IAO_0000115: Abnormal release of whole blood or the cellular component from the circulation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:119

ecchymosis
type: Class
subclass of: hemorrhage and non-specified extravasation
IAO_0000115: A red/purple patch caused by extravasation of blood into the skin. Larger than petechiae.
has OBO namespace: mouse_pathology.ontology
id: MPATH:120
comment: May also be used for any organ, although more generally used with respect to the skin.

hematoma
type: Class
subclass of: hemorrhage and non-specified extravasation
IAO_0000115: A localised deposition of clotted or partially clotted extravasated blood.
has OBO namespace: mouse_pathology.ontology
has related synonym: Bruise
id: MPATH:121

infarct
type: Class
subclass of: circulatory disorder
IAO_0000115: An area of necrosis resulting from a sudden cessation of arterial or venous blood supply.
has OBO namespace: mouse_pathology.ontology
id: MPATH:124

growth and differentiation defect
type: Class
subclass of: pathological anatomical entity
IAO_0000115: Defects in growth (changes in proliferation or mass) and differentiation of cells tissues or organs.
has OBO namespace: mouse_pathology.ontology
id: MPATH:126

atrophy
type: Class
subclass of: defective growth and differentiation process
IAO_0000115: A reduction in size of organs or tissues as a result of cell death, loss of cellularity of whatever cause, reduced cellular proliferation or decreased cellular volume.
has OBO namespace: mouse_pathology.ontology
id: MPATH:127

process of degenerative change
type: Class
subclass of: cell and tissue damage process
IAO_0000115: A pathological process of loss or degradation of function, or structural integrity, of a tissue, organ or cell.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:14

squamous hyperplasia
type: Class
subclass of: hyperplastic tissue
IAO_0000115: Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia).
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
has related synonym: epidermal hyperplasia.
has related synonym: squamous cell hyperplasia
id: MPATH:149

acanthosis
type: Class
subclass of: squamous hyperplasia
IAO_0000115: Hyperplasia of the Malpighian layer (prickle cell) of the epidermis.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:150

hyperkeratosis
type: Class
subclass of: squamous hyperplasia
IAO_0000115: Thickening of the surface layers (stratum corneum) in the skin or other stratified squamous epithelium. Cf. ortho- and para-keratosis.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
has related synonym: cornification
has related synonym: hyperorthokeratosis
has related synonym: hyperparakeratosis
id: MPATH:154

parakeratosis
type: Class
subclass of: hyperkeratosis
IAO_0000115: Thickening of the surface cell layer of a stratified squamous epithelium with retention of nuclei in the cells of the stratum corneum.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:156

metaplasia
type: Class
subclass of: defective growth and differentiation process
IAO_0000115: Abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind. An adult instance of developmental transdifferentiation MPATH:85 Traditionally defined as a form of abnormal regeneration in which a type of cell different from that found normally in a given location is produced.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:160

epithelial metaplasia
type: Class
subclass of: metaplastic tissue
IAO_0000115: Metaplasia occurring within epithelia.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:162

gastric metaplasia
type: Class
subclass of: epithelial metaplasia
IAO_0000115: Appearance of heterotopic gastric epithelium.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:164

healing and repair process
type: Class
subclass of: pathological process
IAO_0000115: The process, normal or abnormal, of damage repair or wound closure.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:175

connective tissue replacement
type: Class
subclass of: healing and repair process
IAO_0000115: Replacement of connective tissue by fibro-fatty deposits and scar tissue.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:176

fibrosis
type: Class
subclass of: connective tissue replacement
IAO_0000115: Reactive formation of fibrous tissue.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:181

sclerosis
type: Class
subclass of: connective tissue replacement
IAO_0000115: Any pathological thickening or hardening of a tissue.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
has related synonym: Induration
id: MPATH:184

immunopathological process
type: Class
subclass of: pathological process
IAO_0000115: Inappropriate or aberrant activation or suppression of the immune or inflammatory response.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:188

immune mediated disease
type: Class
subclass of: immunopathological process
IAO_0000115: Tissue response to inappropriate immune/inflammatory process.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:194

arthritis
type: Class
subclass of: inflammation
IAO_0000115: Inflammation of a joint.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:195

dermatitis
type: Class
subclass of: inflammation
IAO_0000115: Inflammation of the skin.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:196

glomerulonephritis
type: Class
subclass of: inflammation
IAO_0000115: Renal disease characterised by diffuse inflammatory changes in glomeruli not in response to an infectious agent or treatment.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:197

immune mediated hemolytic anaemia
type: Class
subclass of: inflammation
IAO_0000115: An anemic/erythrocytopenic condition resulting from an increased rate of immune mediated erythrocyte destruction.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:198

cell death
type: Class
subclass of: cell and tissue damage process
IAO_0000115: Complete and irreversible cessation of metabolic activity.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:2

myositis
type: Class
subclass of: inflammation
IAO_0000115: Inflammation of a muscle.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
has related synonym: Initis
id: MPATH:200

vasculitis
type: Class
subclass of: inflammation
IAO_0000115: Inflammation of a blood vessel.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
has related synonym: angiitis
has related synonym: arteritis
has related synonym: lymphangiitis
has related synonym: phlebitis
id: MPATH:201

inflammation
type: Class
subclass of: immune mediated disease
IAO_0000115: A tissue reaction to an internal or external injury.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:212

acute inflammation
type: Class
subclass of: inflammation
IAO_0000115: Inflammation with a recent onset, characterised histologically by primarily granulocyte infiltration, edema and hyperemia.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:213
comment: The five classical signs of inflammation: Rubor, tumor, calor, dolor, functio laesa (Galen 300BC).

chronic inflammation
type: Class
subclass of: inflammation
IAO_0000115: Chronic inflammatory condition characterised by infiltration of primarily lymphocytes.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:214

neoplasm
type: Class
equivalent class: Neoplasm
subclass of: pathological anatomical entity
IAO_0000115: A tumor resulting from abnormal and uncontrolled autonomous new cell growth (proliferation)that may be benign or malignant.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:218

adnexal and skin appendage tumor
type: Class
subclass of: neoplasm
IAO_0000115: Tumors of the skin, its constituent structures and glands including the mammary gland, apocrine and eccrine glands, hair follicles and associated structures.
created by: George Gkoutos
has OBO namespace: mouse_pathology.ontology
id: MPATH:219

trichoepithelioma
type: Class
equivalent class: Hair Follicle Neoplasm
subclass of: basaloid follicular neoplasms
IAO_0000115: Multiple small benign nodules derived from basal cells of hair follicles enclosing small cornified cell containing cysts. (M-8100/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: Epithelioma adenoides cysticum
has related synonym: benign
has related synonym: hair follicle tumor
id: MPATH:232

basal cell tumor
type: Class
equivalent class: Basal Cell Neoplasm
subclass of: adnexal and skin appendage tumor
subclass of: adenoma
IAO_0000115: Well circumscribed tumor of the basal cells of the epidermis. Rare mitotic figures, benign. (M8147/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: Benign basal cell tumor
has related synonym: basal cell adenoma
id: MPATH:233

basal cell carcinoma
type: Class
equivalent class: Skin Basal Cell Carcinoma
subclass of: carcinoma
subclass of: basaloid follicular neoplasms
IAO_0000115: Malignant neoplasm of the basal cells of the epidermis with local invasion. (M-8090/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:234

blood vessel tumor
type: Class
equivalent class: Blood Vessel Neoplasm
subclass of: neoplasm
IAO_0000115: Tumor of venous or arterial vessels or capillaries.
has OBO namespace: mouse_pathology.ontology
id: MPATH:235

angiofibroma
type: Class
equivalent class: Angiofibroma
subclass of: blood vessel tumor
IAO_0000115: .A benign neoplasm of fibrous tissue in which there are multiple large and small dilated vascular channels ( M9160/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: Telangiectatic fibroma
id: MPATH:236

hemangioblastoma
type: Class
equivalent class: Hemangioblastoma
subclass of: blood vessel tumor
IAO_0000115: A benign neoplasm frequently arising in the cerebellum composed of capillary vessel forming endothelial cells and stromal cells. (M-9161/1).
has OBO namespace: mouse_pathology.ontology
has related synonym: Angioblastoma
id: MPATH:238

hemangioma
type: Class
equivalent class: Hemangioma
subclass of: blood vessel tumor
IAO_0000115: Neoplasm derived from endothelial cells. May be of capillary or cavernous type with large vascular channels. (M-9130/0 + M-9120/0 respectively).
has OBO namespace: mouse_pathology.ontology
has related synonym: Angioendothelioma.
has related synonym: Hemangioendothelioma, benign
id: MPATH:240

hemangiosarcoma
type: Class
equivalent class: Angiosarcoma
subclass of: blood vessel tumor
subclass of: sarcoma
IAO_0000115: Malignant neoplasm derived from pluripotential mesenchymal stem cells or endothelial cells of blood vessels. (M-9120/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Hemangioma malignant
has related synonym: hemangioendothelioma malignant, angiosarcoma
has related synonym: hemangioendothelioma malignant.
id: MPATH:242

central nervous system tumor
type: Class
equivalent class: Central Nervous System Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasm of the neurones, glia or meninges of the CNS.
has OBO namespace: mouse_pathology.ontology
id: MPATH:243

astrocytoma
type: Class
equivalent class: Astrocytoma
subclass of: glioma
IAO_0000115: Glioma derived from astrocytes, both benign and malignant forms (M-9400/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Astrocytic glioma
has related synonym: astroglioma
id: MPATH:244
comment: Also see comments in Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

choroid plexus papilloma
type: Class
equivalent class: Choroid Plexus Papilloma
subclass of: fibroepithelial tumor
subclass of: tumors of neurepithelial tissue
IAO_0000115: Benign neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:246

ependymoma
type: Class
equivalent class: Ependymoma
subclass of: glioma
IAO_0000115: Neoplasm derived from the ependymal cells lining the ventricles and aqueduct of the brain and the central canal of the spinal cord. Malignant or benign. (M-9391/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:247
comment: Also see general scheme in Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

glioma
type: Class
equivalent class: Glioma
subclass of: tumors of neurepithelial tissue
IAO_0000115: Neoplasm derived from astrocytes and oligodendrocytes. (M-9380/3, M-9440/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:249
comment: Also see comments in: Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

tissue specific degenerative process
type: Class
subclass of: process of degenerative change
IAO_0000115: Degenerative process characteristic of a particular tissue.
has OBO namespace: mouse_pathology.ontology
id: MPATH:25

medulloblastoma
type: Class
equivalent class: Medulloblastoma
subclass of: CNS progenitor tumor
IAO_0000115: Neoplasm derived from the primitive neurectodermal cells of the cerebellum. (M-9470/3). May be considered by some authorities a synonym of PNET in the CNS.
has OBO namespace: mouse_pathology.ontology
id: MPATH:250
comment: Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

meningioma
type: Class
equivalent class: Meningioma
subclass of: tumors of the meninges
IAO_0000115: meningioma
has OBO namespace: mouse_pathology.ontology
has related synonym: Sarcoma, meningeal ( sensu malignant tumor)
id: MPATH:251
comment: Benign or malignant neoplasm derived from the meninges. (M-9530/0).

oligodendroglioma
type: Class
equivalent class: Oligodendroglioma
subclass of: glioma
IAO_0000115: Benign or malignant neoplasm derived form oligodendrocytes (M-9450/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Glioma, oligodendritic, benign
has related synonym: glioma oligodendritic, malignant
id: MPATH:252
comment: Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

complex tumor
type: Class
subclass of: neoplasm
IAO_0000115: Tumors showing mutiple histological componants/differentiation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:254

nephroblastoma
type: Class
equivalent class: Kidney Wilms Tumor
subclass of: complex tumor
IAO_0000115: Embryonal tumor thought to be derived from metanephric blastema. Mono, bi or triphasic, sometimes with heterotypic differentiation. (M-8960/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: nephroma
id: MPATH:261

pulmonary blastoma
type: Class
equivalent class: Pulmonary Blastoma
subclass of: complex tumor
IAO_0000115: A biphasic tumor containing a primitive epithelial component, that may resemble well-differentiated fetal adenocarcinoma and a primitive mesenchymal stroma, which occasionally has foci of osteosarcoma, chondrosarcoma or rhadomyosarcoma. (M-8972/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:262

fibroepithelial tumor
type: Class
equivalent class: Fibroepithelial Neoplasm
subclass of: neoplasm
IAO_0000115: Tumors with epithelial invaginations/linings and a fibrillary and fibrocytic stroma. (M-9000 - M-9030).
has OBO namespace: mouse_pathology.ontology
id: MPATH:264

fibroadenoma
type: Class
equivalent class: Fibroadenoma
subclass of: fibroepithelial tumor
IAO_0000115: A benign neoplasm derived from glandular epithelium, in which there is a abundant stroma of proliferating fibroblasts and connective tissue. (M-9010/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:266

glandular tumor
type: Class
subclass of: neoplasm
IAO_0000115: Neoplasms derived from glandular epithelial cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:267

adenocarcinoma
type: Class
equivalent class: Adenocarcinoma
subclass of: glandular tumor
subclass of: carcinoma
IAO_0000115: Malignant neoplasm of epithelial cells in glandular or glandlike pattern. (M-8140/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:268

arthrosis
type: Class
subclass of: tissue specific degenerative process
IAO_0000115: Changes characterized by erosion of articular cartilage, either primary or secondary to trauma or other conditions. Not primarily an inflammatory process.
has OBO namespace: mouse_pathology.ontology
has related synonym: Degenerative joint disease
has related synonym: osteoarthrosis
id: MPATH:27

adenoma
type: Class
equivalent class: Adenoma
subclass of: glandular tumor
subclass of: potentially cancerous lesions
IAO_0000115: A benign epithelial neoplasm in which the tumor cells may form glands or glandlike structures. In different instances this may remain a benign tumor or progress to malignancy.
has OBO namespace: mouse_pathology.ontology
id: MPATH:270

adenomatous polyposis coli
type: Class
equivalent class: Familial Adenomatous Polyposis
subclass of: glandular tumor
subclass of: potentially cancerous lesions
IAO_0000115: Spontaneous intestinal adenoma formation. Polyps increase in number, causing symptoms of chronic colitis and potentially transform into adenocarcinoma. (M-8220/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:271

cystadenoma
type: Class
equivalent class: Cystadenoma
subclass of: adenoma
IAO_0000115: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:277

follicular adenocarcinoma
type: Class
equivalent class: Thyroid Gland Follicular Carcinoma
subclass of: adenocarcinoma
IAO_0000115: Originates in the follicular cells of thyroid follicles. Papillary, solid and follicular forms. (M- 8330/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Follicular carcinoma
id: MPATH:278

atherosclerosis
type: Class
subclass of: tissue specific degenerative process
IAO_0000115: Characterised by irregular lipid deposits in the wall of arteries, causing narrowing of their lumens and proceeding eventually to fibrosis and calcification.
has OBO namespace: mouse_pathology.ontology
id: MPATH:28
comment: Note that in mouse and rats the initial lesions are mostly in the medial layer while in human they occur in the intima.

islet cell adenoma
type: Class
subclass of: adenoma
IAO_0000115: Usually pancreatic B cell derived tumors mostly producing insulin. (M- 8150/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: Adenoma, endocrine pancreas
has related synonym: adenomatosis
has related synonym: islet (pancreatic) cell tumor benign
id: MPATH:287

medullary carcinoma
type: Class
equivalent class: Thyroid Gland Medullary Carcinoma
subclass of: glandular tumor
subclass of: carcinoma
IAO_0000115: Derived from calcitonin-producing cells (thyroid). In humans a type of carcinoma composed of epithelial elements with considerable lymphoid stroma (breast). Not yet reported in mice. (M-8510/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Medullary adenocarcinoma
id: MPATH:291

papillary adenocarcinoma
type: Class
equivalent class: Papillary Adenocarcinoma
subclass of: adenocarcinoma
IAO_0000115: A malignant neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:295

papillary cystadenoma
type: Class
equivalent class: Papillary Cystadenoma
subclass of: adenoma
IAO_0000115: A benign neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:298

pinealoma
type: Class
equivalent class: Pineal Region Neoplasm
subclass of: glandular tumor
IAO_0000115: Originating from differentiated cells of the pineal parenchyma. Not to be confused with human pinealoma (syn: germinoma) non-gonadal germ cell tumors found in the pineal believed to be atypical teratomas. May be benign or malignant. If ectopic teratomas/teratocarcinomas use MP322 or MP321. (M-9360/1).
has OBO namespace: mouse_pathology.ontology
id: MPATH:299

thyroid C-cell carcinoma
type: Class
subclass of: glandular tumor
subclass of: carcinoma
IAO_0000115: Malignant neoplasm derived from the calcitonin producing C-cells of the thyroid gland. (M-8510/3, M-8345/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Medullary carcinoma, parafollicular cell
has related synonym: tumor c-cell malignant
id: MPATH:308

gonadal tumor
type: Class
subclass of: neoplasm
IAO_0000115: Germ cell and non-germ cell tumors of the testis and ovary.
has OBO namespace: mouse_pathology.ontology
id: MPATH:309

emphysema
type: Class
subclass of: tissue specific degenerative process
IAO_0000115: Abnormal accumulation of air in the interstitial connective tissue of a structure. Sensu Lung: Pulmonary emphysema; characterised by abnormal increase in the size of air (alveolar) spaces distal to the terminal bronchiole with degenerative changes in their walls and reduction in their number.
has OBO namespace: mouse_pathology.ontology
id: MPATH:31

germ cell tumor
type: Class
equivalent class: Germ Cell Tumor
subclass of: gonadal tumor
IAO_0000115: Neoplasms derived from germ cells. May be gonadal or extragonadal and are derived from primordial germ cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:310

dysgerminoma
type: Class
equivalent class: Dysgerminoma
subclass of: germ cell tumor
IAO_0000115: Undifferentiated germ cell tumor of the ovary composed of solid sheets of large polygonal cells with rim of clear cytoplasm (M-9060/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Seminoma (sensu male)
id: MPATH:312

gonadoblastoma
type: Class
equivalent class: Gonadoblastoma
subclass of: germ cell tumor
IAO_0000115: Gonadal neoplasms that consist of aggregates of germ cells and sex cord elements (M-9073/1).
has OBO namespace: mouse_pathology.ontology
has related synonym: Gonocytoma
id: MPATH:315

mixed germ cell tumor
type: Class
equivalent class: Mixed Germ Cell Tumor
subclass of: complex tumor
subclass of: germ cell tumor
IAO_0000115: Malignant neoplasm of the testis/ovary including various elements of germ cell tumors (M-9085/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Mixed teratoma and seminoma
id: MPATH:316

seminoma
type: Class
equivalent class: Seminoma
subclass of: germ cell tumor
IAO_0000115: Tumor derived from spermatogenic cells resembling spermatogenia or spermatocytes. NOS ( M9061/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: Germinoma, malignant
has related synonym: dysgerminoma
has related synonym: spermatoblastoma
has related synonym: spermatocytoma, malignant.
id: MPATH:317

teratocarcinoma
type: Class
equivalent class: Mixed Embryonal Carcinoma and Teratoma
subclass of: complex tumor
subclass of: germ cell tumor
subclass of: carcinoma
IAO_0000115: Mixed germ cell neoplasm contaning elements of embryonal carcinoma and teratoma (M-9081/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:321

teratoma
type: Class
equivalent class: Teratoma
subclass of: complex tumor
subclass of: germ cell tumor
IAO_0000115: Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Malignant tumors are highly metatstatic. (M-9080/1).
has OBO namespace: mouse_pathology.ontology
id: MPATH:322

gonadal somatic cell tumor
type: Class
subclass of: gonadal tumor
IAO_0000115: Neoplasms derived from the non-germ cell derived tissues of the testis and ovary.
has OBO namespace: mouse_pathology.ontology
id: MPATH:323

leydig cell tumor
type: Class
equivalent class: Leydig Cell Tumor
subclass of: gonadal somatic cell tumor
IAO_0000115: Tumor derived from Leydig cells (M-8650/1).
has OBO namespace: mouse_pathology.ontology
has related synonym: Interstitial cell tumor, benign
has related synonym: Leydig cell adenoma
id: MPATH:328

intracellular and extracellular accumulation
type: Class
subclass of: cell and tissue damage
IAO_0000115: Accumulation of substances within, on the surface of or between cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:33

sertoli cell tumor
type: Class
equivalent class: Sertoli Cell Tumor
subclass of: gonadal somatic cell tumor
IAO_0000115: Tumor derived from sex cord/stromal cells; Sertoli cells and can occur in both testis and ovary. (M-8640/1).
has OBO namespace: mouse_pathology.ontology
has related synonym: Androblastoma
has related synonym: arrhenoblastoma
has related synonym: gonadal stromal tumor
has related synonym: sex cord stromal tumor
has related synonym: sustentacluar tumor
id: MPATH:331

hematopoietic/lymphoid malignancies/disorder
type: Class
subclass of: neoplasm
IAO_0000115: Proliferative disorders and malignancies of the lymphoid and non lymphoid haematopoietic lineages.
has OBO namespace: mouse_pathology.ontology
id: MPATH:335

amyloid deposition
type: Class
subclass of: intracellular and extracellular accumulation
IAO_0000115: Extracellular deposition of amyloid protein.
has OBO namespace: mouse_pathology.ontology
has related synonym: Amyloidosis
id: MPATH:34
comment: Any group of chemically diverse proteins that appears microscopically homogeneous, but is composed of linear non-branching aggregated fibrils aranged in sheets when see under the electron microscope.

myeloid leukaemia
type: Class
subclass of: Non-Lymphoid leukaemias
IAO_0000115: Leukaemias of the myeloid lineage.
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
has related synonym: granulocytic leukaemia
id: MPATH:342

autoimmune mediated disease
type: Class
subclass of: immune mediated disease
created by: George Gkoutos
creation date: 2011-03-22T01:12:01Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:346

thymoma
type: Class
equivalent class: Thymoma
subclass of: potentially cancerous lesions
IAO_0000115: A neoplasm in the anterior mediastinum, originating from thymic tissue, usually benign, and frequently encapsulated; occasionally invasive, but metastases are rare; histologically, consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. (M-8580/1).
has OBO namespace: mouse_pathology.ontology
id: MPATH:351

hepatic tumor
type: Class
subclass of: neoplasm
IAO_0000115: Tumors of the liver and biliary apparatus.
has OBO namespace: mouse_pathology.ontology
id: MPATH:352

hepatocellular adenoma
type: Class
equivalent class: Hepatocellular Adenoma
subclass of: adenoma
subclass of: hepatic tumor
IAO_0000115: Benign neoplasm derived from hepatocytes. (M- 8170/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: hepatic adenoma, benign, liver cell tumor, benign
has related synonym: hepatoma, benign
has related synonym: nodule type A
id: MPATH:353

cholangiocarcinoma
type: Class
equivalent class: Cholangiocarcinoma
subclass of: hepatic tumor
subclass of: carcinoma
IAO_0000115: Malignant tumor derived from the bile duct epithelium. (M8160/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:354

hepatoblastoma
type: Class
equivalent class: Hepatoblastoma
subclass of: hepatic tumor
IAO_0000115: Malignant neoplasm of the liver of unknown origin . Liver blastemal cells, neoplastic hepatocytes, oval cells and biliary epithelial cells have been proposed. (M- 8970/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: embryonal hepatoma
has related synonym: tumor, mixed, poorly differentiated
id: MPATH:356

hepatocellular carcinoma
type: Class
equivalent class: Hepatocellular Carcinoma
subclass of: hepatic tumor
subclass of: carcinoma
IAO_0000115: Malignant tumor derived from hepatocytes. (M- 8170/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: carcinoma, trabecular
has related synonym: carcinoma, trabecular (liver)
has related synonym: hepatoma, malignant
has related synonym: nodule type B
id: MPATH:357

melanocytic tumor
type: Class
subclass of: adnexal and skin appendage tumor
IAO_0000115: Tumors derived from melanocytes.
has OBO namespace: mouse_pathology.ontology
id: MPATH:358

melanoma
type: Class
equivalent class: Melanoma
subclass of: melanocytic tumor
IAO_0000115: Tumor of neurectodermal origin, usually melanocytes, showing dense deposition of melanin granules, although amelanotic melanomas have been reported. (M-8720/3).
has db xref: URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models/malignant_melanoma#melanoma_table
has OBO namespace: mouse_pathology.ontology
has related synonym: melanosarcoma
has related synonym: melanosarcoma, malignant melanoma
id: MPATH:359

calcium deposition
type: Class
subclass of: mineralisation
IAO_0000115: Intra or extracellular deposition of calcium usually as calcium phosphate.
has OBO namespace: mouse_pathology.ontology
id: MPATH:36

melanoma in situ
type: Class
equivalent class: Stage 0 Skin Melanoma
subclass of: melanocytic tumor
subclass of: potentially cancerous lesions
IAO_0000115: A potentially malignant lesion, melanoma in situ is the first phase of growth of melanoma, in which it is still confined to the epithelial domain (epidermis and adnexa) and has not passed through the basement membrane. (M-8720/2).
has OBO namespace: mouse_pathology.ontology
has related synonym: level I melanoma
id: MPATH:360

naevus
type: Class
subclass of: melanocytic tumor
IAO_0000115: Local lesion of the skin, often colored by hyperpigmentation or increased vascularity. May be predominantly epidermal, adnexal, melanocytic, vascular, or mesodermal, or a compound overgrowth of these tissues. Not necessarily pre-malignant. (M-8720/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: mole (sensu melanocytic nevus)
id: MPATH:361

mesothelioma
type: Class
equivalent class: Mesothelioma
subclass of: neoplasm
IAO_0000115: Benign or malignant neoplasm derived from the lining cells of the pleura and peritoneum, composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells. Epithelioid, fibrous, cystis, papillary, and sarcomatoid variants. (M- 9050/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:365

neuroendocrine tumor
type: Class
equivalent class: Neuroendocrine Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasms derived from the neuroendocrine system.
has OBO namespace: mouse_pathology.ontology
id: MPATH:366

primitive neurectodermal tumor
type: Class
equivalent class: Primitive Neuroectodermal Tumor
subclass of: CNS progenitor tumor
subclass of: peripheral nervous system tumors
IAO_0000115: Primitive neuroectodermal tumors (PNET) are neoplasms derived from primitive neural stem cells either in the CNS or the periphery . These are small-cell, malignant embryonal tumors showing divergent differentiation of variable degree along neuronal, glial, or rarely mesenchymal lines. (M-9473/3, M-9364/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: PNET
id: MPATH:370

small cell carcinoma
type: Class
equivalent class: Small Cell Carcinoma
subclass of: neuroendocrine tumor
subclass of: carcinoma
IAO_0000115: Neuroendocrine cell derived anaplastic carcinoma composed of small cells, usually of the lung producing a variety of peptide hormones. (M-8041/3). 1.2.3.4 of MMHCC classification.
has db xref: URL: http://emice.nci.nih.gov/mouse_models/organ_models/lung_models/murinecancer/tumorclass
has OBO namespace: mouse_pathology.ontology
has related synonym: oat cell carcinoma
id: MPATH:371
comment: see: Meuwissen, R., Linn, S.C., Linnoila, R.I. et al. (2003) Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer cell, 4: 181-189. AND Calbo, J., Meuwissen, R., van Montfort, E. et al. (2005) Genotype-phenotype relationships in a mouse model for human small-cell lung cancer. Cold Spring Harbor symposia on quantitative biology, 70: 225-232. AND Meuwissen, R. and Berns, A. (2005) Mouse models for human lung cancer. Genes & development, 19: 643-664.

CNS progenitor tumor
type: Class
subclass of: tumors of neurepithelial tissue
IAO_0000115: Neoplasms derived from neuroepithelial precursors.
has OBO namespace: mouse_pathology.ontology
id: MPATH:373
comment: Renamed from neuroepitheliomatous tumor, to reflect primitive origins of this class of tumor.

ganglioneuroma
type: Class
equivalent class: Ganglioneuroma
subclass of: peripheral nervous system tumors
IAO_0000115: A benign neoplasm composed of mature ganglionic neurons scattered singly or in clumps within a relatively abundant and dense stroma of neurofibrils and collagenous fibers. (M-9490/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:375

neuroblastoma
type: Class
equivalent class: Neuroblastoma
subclass of: CNS progenitor tumor
IAO_0000115: A malignant neoplasm characterized by immature, poorly differentiated nerve cells of embryonic type. (M-9500/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:376

pheochromocytoma
type: Class
equivalent class: Adrenal Gland Pheochromocytoma
subclass of: neuroendocrine tumor
IAO_0000115: A catecholamine-secreting tumor arising from the chromaffin cells of the sympathetic nervous system or adrenal medulla. May be benign or malignant. [See MPATH 398]. (M- 8510/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:377

retinoblastoma
type: Class
equivalent class: Retinoblastoma
subclass of: CNS progenitor tumor
IAO_0000115: Malignant juvenile neoplasm of the eye derived from primitive retinal precursor cells. (M- 9510/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:378

odontogenic tumor
type: Class
equivalent class: Odontogenic Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasm arising from the tissues of the odontogenic apparatus. These tumors are derived from ectodermal tissue (epithelial tumors) or from mesodermal tissue (connective tissue tumors) or are composed of both components (mixed or composite odontogenic tumors) .
has OBO namespace: mouse_pathology.ontology
id: MPATH:379

odontoma
type: Class
subclass of: complex tumor
subclass of: odontogenic tumor
subclass of: hamartoma
IAO_0000115: Hamartomatous malformation of odontogenic tissue. It may vary from nondescript masses of dental tissue (complex odontoma) to multiple well-formed teeth (compound odontoma). Cf ameloblastic fibro-odontoma. (M-9280/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:387

osseous and chondromatous tumor
type: Class
subclass of: neoplasm
IAO_0000115: Neoplasms of bone and cartilage.
has OBO namespace: mouse_pathology.ontology
id: MPATH:388

chondrosarcoma
type: Class
equivalent class: Chondrosarcoma
subclass of: osseous and chondromatous tumor
IAO_0000115: Malignant neoplasm derived form pluripotential mesenchymal cells, chondrocytes or chondroblasts. No production of osteoid. (M-9220/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:392

osteoma
type: Class
equivalent class: Osteoma
subclass of: osseous and chondromatous tumor
IAO_0000115: Benign neoplasm derived from osteoblasts or osteocytes composed of very dense bone with predominantly woven structure. ( M-9180/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: cancellous osteoma
has related synonym: compact osteoma
has related synonym: juxtacortical osteoma
has related synonym: medullary osteoma
has related synonym: osteoid osteoma
has related synonym: spongious osteoma
has related synonym: trabecular osteoma
id: MPATH:396

osteosarcoma
type: Class
equivalent class: Osteosarcoma
subclass of: osseous and chondromatous tumor
IAO_0000115: Malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes. Highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone. (M-9180/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: osteogenic sarcoma
id: MPATH:397

paragangliomas and glomus tumor
type: Class
subclass of: neuroendocrine tumor
IAO_0000115: Generally benign neoplasms of CHIEF cells arising from neuroectodermal tissues, found in various parts of the body. Note that until recently, glomus tumors were believed to be derived from specialised vascular cells, which is incorrect. Paraganglioma is the preferred term.The nomenclature for pheochromocytoma and paraganglioma is inconsistent. The term paraganglioma is used to refer to any extra-adrenal tumor of the paraganglion system or nonfunctional tumor of the paraganglion system. Functional tumors are referred extra-adrenal pheochromocytoma.
has OBO namespace: mouse_pathology.ontology
id: MPATH:398

necrosis
type: Class
subclass of: cell death
IAO_0000115: Morpholological changes after intravital (Pathologic) death of one or more cells, or of a portion of tissue or organ, resulting from irreversible damage;characterised by mitochondrial swelling, nuclear pyknosis, karyolysis, swollen and abnormally pale basophilic staining; or karyorrhexis, rupture and fragmentation of the nucleus. Energy independent cf. Apoptosis MPATH 3.
has OBO namespace: mouse_pathology.ontology
id: MPATH:4

paraganglioma
type: Class
equivalent class: Paraganglioma
subclass of: paragangliomas and glomus tumor
IAO_0000115: A neoplasm composed of derivatives of CHIEF cells usually in single encapsulated nodular masses surrounded with sustentacular cells. ( M- 8711/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: chemodectomas
has related synonym: glomus tumor
has related synonym: non-chromaffin paragangliomas
id: MPATH:403

soft tissue tumor
type: Class
equivalent class: Soft Tissue Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasms of the soft and connective tissues.
has OBO namespace: mouse_pathology.ontology
id: MPATH:404

chordoma
type: Class
equivalent class: Chordoma
subclass of: soft tissue tumor
IAO_0000115: Believed to arise from primitive notochord remnants . Usually occurs along the axial skeleton and is characterised by the presence of bubble cells containing large unstained cytoplasmic vacuoles with central or eccentricc nuclei. Benign but locally invasive. (M-9370/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:405

fibroma
type: Class
equivalent class: Fibroma
subclass of: soft tissue tumor
subclass of: sarcoma
IAO_0000115: Benign neoplasm of fibroblasts/fibrocytes with poor/moderate cellularity. (M-8810/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:407
comment: "Soft tissue" qualifier removed by Pathology Panel to increase scope of term.

soft tissue fibrosarcoma
type: Class
equivalent class: Soft Tissue Fibrosarcoma
subclass of: soft tissue tumor
subclass of: sarcoma
IAO_0000115: Malignant tumor derived from pluripotential mesenchymal stem cells; fibroblasts, fibrocytes (M-8810/3).
has exact synonym: fibrosarcoma
has OBO namespace: mouse_pathology.ontology
id: MPATH:408

lipomatous tumor
type: Class
equivalent class: Lipomatous Neoplasm
subclass of: soft tissue tumor
IAO_0000115: Tumors derived from the lipogenic lineage or showing predominantly lipomatous differentiation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:415

angiomyolipoma
type: Class
equivalent class: Angiomyolipoma
subclass of: complex tumor
subclass of: lipomatous tumor
IAO_0000115: Benign renal neoplasm composed of fat, vascular, and smooth muscle elements. Associated with tuberous sclerosis in humans. Aetiology unknown, but the combination of elements may reflect a lesion specific pattern of metaplasia. (M-8860/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:416

lipoma
type: Class
equivalent class: Lipoma
subclass of: lipomatous tumor
IAO_0000115: Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous. (M- 8850/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:417

lymphatic vessel tumor
type: Class
equivalent class: Lymphatic Vessel Neoplasm
subclass of: soft tissue tumor
IAO_0000115: Neoplasms of the lymphatic vessels.
has OBO namespace: mouse_pathology.ontology
id: MPATH:419

lymphangioma
type: Class
equivalent class: Lymphangioma
subclass of: lymphatic vessel tumor
subclass of: hamartoma
IAO_0000115: Benign hamartomatous malformation of the lymphatic ducts. Usually found in the skin and may be superficial or deep. (M-9170/0).
has broad synonym: Hygroma
has OBO namespace: mouse_pathology.ontology
id: MPATH:420

myomatous tumor
type: Class
equivalent class: Myomatous Neoplasm
subclass of: soft tissue tumor
IAO_0000115: Neoplasms derived from myogenic lineages or predominantly composed of cells showing myomatous differentiation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:423

leiomyoma
type: Class
equivalent class: Leiomyoma
subclass of: myomatous tumor
IAO_0000115: Benign neoplasm derived from smooth muscle cells. (M-8890/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:425

leiomyosarcoma
type: Class
equivalent class: Leiomyosarcoma
subclass of: myomatous tumor
subclass of: sarcoma
IAO_0000115: Malignant tumor derived form pluripotential mesenchymal stem cells or smooth muscle cells. (M- 8890/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:426

rhabdomyosarcoma
type: Class
equivalent class: Rhabdomyosarcoma
subclass of: myomatous tumor
subclass of: sarcoma
IAO_0000115: Malignant tumor of striated muscle or pluripotential mesenchymal stem cells. (M-8900/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:428

myxomatous tumor
type: Class
subclass of: soft tissue tumor
IAO_0000115: Neoplasms resembling primitive mesenchymal tissue with a soft mucous matrix.
has OBO namespace: mouse_pathology.ontology
id: MPATH:429

myxoma
type: Class
equivalent class: Myxoma
subclass of: myxomatous tumor
IAO_0000115: A benign neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. May show multiple differentiated components. (M-8840/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:431

nerve sheath tumor
type: Class
equivalent class: Nerve Sheath Neoplasm
subclass of: soft tissue tumor
subclass of: peripheral nervous system tumors
IAO_0000115: Neoplasms of the nerve sheath.
has OBO namespace: mouse_pathology.ontology
id: MPATH:433

neurofibroma
type: Class
equivalent class: Neurofibroma
subclass of: nerve sheath tumor
IAO_0000115: Peripheral nerve tumor consisting of chaotic arrays of wavy schwann cell bundles and fibroblasts interspersed within a matrix rich in collagen and mucopolysaccharide. (M9540/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:435

neurofibrosarcoma
type: Class
equivalent class: Malignant Peripheral Nerve Sheath Tumor
subclass of: nerve sheath tumor
subclass of: sarcoma
IAO_0000115: Malignant neoplasm derived from Schwann cells. (M-9540/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: malignant peripheral nerve sheath tumor
id: MPATH:437

schwannoma
type: Class
equivalent class: Schwannoma
subclass of: nerve sheath tumor
IAO_0000115: May be malignant or benign, Schwann cell derived tumor considered to be neurectodermal with some acquired mesenchymal features. (M-9560/0).
has OBO namespace: mouse_pathology.ontology
has related synonym: neurilemoma
has related synonym: neurinoma, benign
id: MPATH:438

squamous cell tumor
type: Class
equivalent class: Squamous Cell Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasms of stratified squamous epithelial cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:442

papilloma
type: Class
equivalent class: Papilloma
subclass of: fibroepithelial tumor
subclass of: potentially cancerous lesions
IAO_0000115: A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells (M-8050/0).
has OBO namespace: mouse_pathology.ontology
id: MPATH:445

squamous cell carcinoma
type: Class
equivalent class: Squamous Cell Carcinoma
subclass of: adnexal and skin appendage tumor
subclass of: squamous cell tumor
subclass of: carcinoma
IAO_0000115: Malignant tumor derived from stratified squamous cells. (M-8070/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: carcinoma, epidermoid ( sensu epidermal derived tumors)
id: MPATH:446

transitional cell tumor
type: Class
equivalent class: Transitional Cell Neoplasm
subclass of: neoplasm
IAO_0000115: Neoplasms of transitional epithelia, eg kidney, ureter , bladder , cervix.
has OBO namespace: mouse_pathology.ontology
id: MPATH:450

transitional cell carcinoma
type: Class
equivalent class: Transitional Cell Carcinoma
subclass of: transitional cell tumor
subclass of: carcinoma
IAO_0000115: Malignant neoplasm of transitional cells (M-8120/3).
has OBO namespace: mouse_pathology.ontology
id: MPATH:451

ectasia
type: Class
subclass of: dilatation
IAO_0000115: Dilation of a tubular structure.
has OBO namespace: mouse_pathology.ontology
id: MPATH:474
comment: Often associated with an obstruction.

telangiectasia
type: Class
subclass of: ectasia
IAO_0000115: A lesion formed by a dilated capillary or terminal artery.
has OBO namespace: mouse_pathology.ontology
id: MPATH:476

adenomatous polyp
type: Class
equivalent class: Adenomatous Polyp
subclass of: adenoma
IAO_0000115: Benign neoplastic growth containing areas of adenomatous structure (progression).
has OBO namespace: mouse_pathology.ontology
has related synonym: polypoid adenoma, cellular polyp.
id: MPATH:490

Non-Lymphoid leukaemias
type: Class
subclass of: Non-Lymphoid neoplasias
IAO_0000115: Neoplasms of non-lymphoid haematopoietic lineage. Must have at least 20% blast cells to meet this definition.
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
id: MPATH:496

monocytic leukaemia
type: Class
subclass of: myeloid leukaemia
IAO_0000115: Leukaemia in which neoplastic cells are poorly or moderately differentiated with a monocytic but no neutrophilic component. At least 20% of the cells must be blasts.
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
id: MPATH:502

non-lymphoid hematopoietic sarcomas
type: Class
subclass of: hematopoietic/lymphoid malignancies/disorder
subclass of: sarcoma
IAO_0000115: Solid tumor mass composed of non-lymphoid haematopoietic cells.
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
id: MPATH:504

histiocytic sarcoma
type: Class
equivalent class: Histiocytic Sarcoma
subclass of: non-lymphoid hematopoietic sarcomas
IAO_0000115: Solid tumor mass composed predominantly of histiocytic cells (M-9775/3).
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
has related synonym: Kupffer cell sarcoma (sensu liver)
has related synonym: histiocytic lymphoma
has related synonym: malignant lymphoma, histiocytic type
has related synonym: reticulum cell sarcoma, type A
has related synonym: reticulum cell sarcoma, type A, reticulosarcoma
id: MPATH:506

Lymphoid neoplasms
type: Class
equivalent class: Lymphocytic Neoplasm
subclass of: hematopoietic/lymphoid malignancies/disorder
IAO_0000115: Neoplasms of the B or T cell lineage.
has OBO namespace: mouse_pathology.ontology
id: MPATH:513

Non-Lymphoid neoplasias
type: Class
subclass of: hematopoietic/lymphoid malignancies/disorder
IAO_0000115: Hematological neoplasias of non-lymphoid origin.
has db xref: URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2
has OBO namespace: mouse_pathology.ontology
id: MPATH:515

B-cell neoplasms
type: Class
equivalent class: B-Cell Neoplasm
subclass of: Lymphoid neoplasms
IAO_0000115: Neoplasm of the B cell lymphoid lineage.
has OBO namespace: mouse_pathology.ontology
id: MPATH:516

Mature B-cell neoplasms
type: Class
equivalent class: Mature B-Cell Neoplasm
subclass of: B-cell neoplasms
IAO_0000115: Lymphomas originating in peripheral B cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:519

Plasma cell neoplasms
type: Class
equivalent class: Plasma Cell Neoplasm
subclass of: B-cell neoplasms
IAO_0000115: Diffuse proliferation of mature plasma cells. Clonal by definition. Includes the equivalent of human myeloma (ICD-O 9732/3).
has db xref: URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/hema_models/hema_mouse_class
has OBO namespace: mouse_pathology.ontology
has related synonym: Myeloma ( human )
id: MPATH:530

plasmacytoma
type: Class
equivalent class: Plasmacytoma
subclass of: Plasma cell neoplasms
IAO_0000115: Diffuse proliferation of mature plasma cells. Clonal by definition.
has db xref: URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/hema_models/hema_mouse_class
has OBO namespace: mouse_pathology.ontology
id: MPATH:532
comment: Tissue, usually lymph nodes, that contain unusually large numbers of normal appearing plasma cells. While these may be plasmacytomas, additional work is needed to confirm this latter diagnosis.

T-cell neoplasms
type: Class
equivalent class: T-Cell and NK-Cell Neoplasm
subclass of: Lymphoid neoplasms
IAO_0000115: Neoplasms derived from cells of the T lymphocyte lineage.
has OBO namespace: mouse_pathology.ontology
id: MPATH:535

precursor T-cell neoplasms
type: Class
subclass of: T-cell neoplasms
IAO_0000115: Neoplasms of precursor T cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:536

precursor T-cell lymphoblastic lymphoma/leukaemia
type: Class
equivalent class: Thymic Lymphoma
subclass of: precursor T-cell neoplasms
IAO_0000115: Precursor T cell derived neoplasia. Most commonly found in the thymus.
has OBO namespace: mouse_pathology.ontology
has related synonym: thymic lymphoma
id: MPATH:537

carcinoma
type: Class
equivalent class: Carcinoma
subclass of: neoplasm
IAO_0000115: Any of various types of malignant neoplasm derived from epithelial cells, chiefly glandular (adenocarcinoma) or squamous (squamous cell carcinoma).
has OBO namespace: mouse_pathology.ontology
id: MPATH:549

developmental and structural abnormality
type: Class
subclass of: pathological anatomical entity
IAO_0000115: Developmental and structural abnormalities occurring during embryonic development or during adult life.
has OBO namespace: mouse_pathology.ontology
id: MPATH:55

sarcoma
type: Class
equivalent class: Sarcoma
subclass of: neoplasm
IAO_0000115: A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:551

mineralisation
type: Class
subclass of: intracellular and extracellular accumulation
IAO_0000115: Deposition of any homogeneous inorganic material.
has OBO namespace: mouse_pathology.ontology
id: MPATH:555

potentially cancerous lesions
type: Class
subclass of: neoplasm
IAO_0000115: Lesions which in some cases have the potential to become progressively growing malignant tumors.
has OBO namespace: mouse_pathology.ontology
id: MPATH:556

developmental or adult structural defect
type: Class
subclass of: developmental and structural abnormality
IAO_0000115: Structural, physical or other general defect of prenatal development of the embryo and the placenta, or such as are acquired in the adult.
has OBO namespace: mouse_pathology.ontology
id: MPATH:56

glioblastoma
type: Class
equivalent class: Glioblastoma
subclass of: glioma
IAO_0000115: Develop primarily through increasing anaplasia of well differentiated gliomas, mainly astrocytomas or oligodendrogliomas. Typically large and contain cells of different sizes with irrregular nuclei and atypical mitotic figures. (M-9440/3).
has OBO namespace: mouse_pathology.ontology
has related synonym: glioblastoma multiforme
has related synonym: monstrocytoma
id: MPATH:564
comment: Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463.

tumors of neurepithelial tissue
type: Class
subclass of: central nervous system tumor
IAO_0000115: Tumors of neuronal and non-neuronal cells derived from embryonic neurepithelium.
has OBO namespace: mouse_pathology.ontology
id: MPATH:565

tumors of the meninges
type: Class
equivalent class: Meningeal Neoplasm
subclass of: central nervous system tumor
IAO_0000115: tumors of the meninges
has OBO namespace: mouse_pathology.ontology
id: MPATH:566

peripheral nervous system tumors
type: Class
equivalent class: Peripheral Nervous System Neoplasm
subclass of: neoplasm
IAO_0000115: Tumors of the peripheral nervous system.
has OBO namespace: mouse_pathology.ontology
id: MPATH:570

pilomatricoma
type: Class
equivalent class: Pilomatricoma
subclass of: basaloid follicular neoplasms
IAO_0000115: Tumor composed of the epithelial components of the most proximal (trichogenic) portion of the hair follicle associated with an aberrent hair cortex type of cornification (ghost cells or shadow cells). The most primitive cellular component consists of basophilic cells having scanty cytoplasm and nuclei that occasionally overlap to some extent. In humans mineralisation is common.
has OBO namespace: mouse_pathology.ontology
id: MPATH:571

nephroblastomatosis
type: Class
subclass of: developmental dysplasia
IAO_0000115: Persistence of metanephrogenic blastema or its presence in the wrong place or at the wrong time. Associated with hyperplastic nephrogenic rests.
has OBO namespace: mouse_pathology.ontology
id: MPATH:574

basaloid follicular neoplasms
type: Class
subclass of: adnexal and skin appendage tumor
IAO_0000115: This is a new diagnostic term that the MMHC pathology panel felt best described a diagnostically challenging set of tumors that share the feature of being compose of basaloid cells showing follicular differentiation to some extent. These tumors are common in GEM involving the hedgehog signaling pathway and frequently have more than one of the histologic patterns listed below. The designation of benign and malignant has been excluded from the primary diagnosis purposely, as this is frequently difficult to determine in these characteristically well circumscribed tumors. The presence of a disorganized (non-palisaded) sheet-like growth pattern, tumor necrosis, or numerous mitoses are felt to represent malignant transformation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:575

trichofolliculoma
type: Class
IAO_0000115: Basaloid neoplasm with numerous mature hair follicles and hair formation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:576

ulcer
type: Class
subclass of: cell and tissue damage
IAO_0000115: Loss of epithelium and the basement membrane (full thickness). Cf Erosion.
has OBO namespace: mouse_pathology.ontology
id: MPATH:579

pathological process
type: Class
subclass of: pathological entity
IAO_0000115: The organic response of tissues to external insult, injury or underlying genetic or epigenetic lesion.
has OBO namespace: mouse_pathology.ontology
id: MPATH:596

cell and tissue damage process
type: Class
subclass of: pathological process
IAO_0000115: Processes occurring during cell and tissue damage of either intrinsic or extrinsic etiology.
has OBO namespace: mouse_pathology.ontology
id: MPATH:597

developmental process abnormalities
type: Class
subclass of: pathological process
IAO_0000115: developmental process abnormalities
has OBO namespace: mouse_pathology.ontology
id: MPATH:599

hyperplastic tissue
type: Class
subclass of: growth and differentiation defect
IAO_0000115: An organ or a tissue with an abnormal increase in the number of cells as a consequence of cell proliferation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:602

pathological anatomical entity
type: Class
subclass of: pathological entity
IAO_0000115: Anatomically located instance of pathological response or entity.
has OBO namespace: mouse_pathology.ontology
id: MPATH:603

defective growth and differentiation process
type: Class
subclass of: pathological process
IAO_0000115: Abnormal increase or decrease in the rate of cell growth or cell division including associated changes in the differentiation state of adult cells.
has OBO namespace: mouse_pathology.ontology
id: MPATH:604
comment: Excludes abnormalities of developmental proliferation and differentiation.

metaplastic tissue
type: Class
subclass of: growth and differentiation defect
IAO_0000115: A tissue or group of cells in which there has been abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind.
has OBO namespace: mouse_pathology.ontology
id: MPATH:605
comment: Nearly exclusively used in an adult context.

healing and repair structure
type: Class
subclass of: pathological anatomical entity
IAO_0000115: Physical entity or structure associated with normal or abnormal tissue healing or repair following extrinsic or intrinsic damage.
has OBO namespace: mouse_pathology.ontology
id: MPATH:607

abscess
type: Class
subclass of: healing and repair structure
IAO_0000115: A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation.
has OBO namespace: mouse_pathology.ontology
id: MPATH:608
comment: Generally occur following damage or infection with subsequent inflammatory response. Result of the body`s defensive reaction to foreign material.

cardiomyopathy
type: Class
subclass of: tissue specific degenerative process
IAO_0000115: A disease of the heart muscle or myocardium proper.
has OBO namespace: mouse_pathology.ontology
id: MPATH:615
comment: Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

cyst
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Formation of an epithelium bounded cavity not associated with neoplasia.
has OBO namespace: mouse_pathology.ontology
id: MPATH:62

steatosis
type: Class
subclass of: intracellular and extracellular accumulation
IAO_0000115: Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells.
has exact synonym: lipidosis
has OBO namespace: mouse_pathology.ontology
has related synonym: adipose degeneration
has related synonym: fatty change
has related synonym: fatty degeneration
id: MPATH:622
comment: Most commonly associated with degenerative change in the liver.

avulsion
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Tearing away or separation of two structures or parts.
has OBO namespace: mouse_pathology.ontology
id: MPATH:625

cavernous hemangioma
type: Class
equivalent class: Cavernous Hemangioma
subclass of: hemangioma
IAO_0000115: Deep cutaneous hemangioma with large dilated vascular spaces that manifests spontaneous involution.
has OBO namespace: mouse_pathology.ontology
id: MPATH:629

developmental dysplasia
type: Class
subclass of: developmental process abnormalities
IAO_0000115: Abnormal development (of organs or tissues) or an abnormal structure resulting from such growth.
has OBO namespace: mouse_pathology.ontology
id: MPATH:64
comment: The word dysplasia as commonly used refers to a precursor state to neoplasia. This is not the context used for this MPATH term.

dilatation
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Increase in the diameter of an orifice or tubular structure beyond its normal dimensions.
has OBO namespace: mouse_pathology.ontology
id: MPATH:66

psoriasiform dermatitis
type: Class
subclass of: dermatitis
created by: George Gkoutos
creation date: 2011-02-19T04:09:12Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:675

diverticulum
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: A blind ended outpouching through the wall of a tubular organ or bounded cavity.
has OBO namespace: mouse_pathology.ontology
id: MPATH:68

spindle cell sarcoma
type: Class
equivalent class: Spindle Cell Sarcoma
subclass of: sarcoma
created by: George Gkoutos
creation date: 2011-02-19T05:12:17Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:695

fistula
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: An abnormal passage between two internal organs or leading from a cavity to the body surface.
has OBO namespace: mouse_pathology.ontology
id: MPATH:70

angiolipoma
type: Class
equivalent class: Angiolipoma
subclass of: lipomatous tumor
created by: George Gkoutos
creation date: 2011-02-20T08:44:41Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:707

alveolar rhabdomyosarcoma
type: Class
equivalent class: Alveolar Rhabdomyosarcoma
subclass of: rhabdomyosarcoma
IAO_0000115: Malignant tumor of striated muscle or pluripotential mesenchymal stem cells composed mainly of small round cells, with some partial skeletal muscle differentiation.
created by: Paul
creation date: 2011-06-06T03:24:13Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:709

embryonal rhabdomyosarcoma
type: Class
equivalent class: Embryonal Rhabdomyosarcoma
subclass of: rhabdomyosarcoma
IAO_0000115: Malignant mesenchymal tumor that morphologically and phenotypically resembles embryonal skeletal muscle.
created by: Paul
creation date: 2011-06-06T03:31:11Z
has exact synonym: Myosarcoma
has OBO namespace: mouse_pathology.ontology
has related synonym: Rhabdopoietic Sarcoma
has related synonym: Sarcoma Botryoides [Soft Tissues]
has related synonym: Embryonal Sarcoma
has related synonym: Malignant Rhabdomyoma
id: MPATH:710
comment: Includes spindle cell, botryoid, anaplastic.

pre-sacral teratoma
type: Class
subclass of: teratoma
IAO_0000115: Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Pre-sacral tumors located in the retrorectal space between the rectum and the sacrococcygeal part of the spine.
created by: Paul
creation date: 2011-06-06T03:39:01Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:718

rhabdomyoma
type: Class
equivalent class: Rhabdomyoma
subclass of: myomatous tumor
IAO_0000115: Benign stromal tumors of the soft tissue with skeletal muscle differentiation.
created by: Paul
creation date: 2011-06-06T03:59:49Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:722
comment: Adult and fetal types.

fibromatosis
type: Class
equivalent class: Fibromatosis
subclass of: fibroma
IAO_0000115: Systemic manifestation of MPATH: 407.
created by: Paul
creation date: 2011-06-06T04:11:04Z
has exact synonym: Desmoid Tumor
has OBO namespace: mouse_pathology.ontology
has related synonym: Musculoaponeurotic Fibromatosis
has related synonym: Aggressive Fibromatosis
has related synonym: Plantar Fibromatosis (Ledderhose Disease)
id: MPATH:723

hamartoma
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: A focal malformation resembling a neoplasm which results from faulty development of an organ; composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element. Growth and location are usually normal for that tissue cf. Heterotopia/Choristoma MPATH:76/MPATH:477.
has OBO namespace: mouse_pathology.ontology
id: MPATH:74

perforation
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Presence of a hole/channel through a normally imperforate structure often a membrane or septum.
has OBO namespace: mouse_pathology.ontology
id: MPATH:81

post-traumatic structural abnormality
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Morphological abnormality following trauma or related insult such as infection.
created by: Paul
creation date: 2012-03-24T03:28:03Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:850

auricular deformation
type: Class
subclass of: post-traumatic structural abnormality
IAO_0000115: acquired dysmorphology of the external pinna following trauma or infection.
created by: Paul
creation date: 2012-03-24T03:29:48Z
has OBO namespace: mouse_pathology.ontology
id: MPATH:851

organ specific developmental defect
type: Class
subclass of: developmental and structural abnormality
IAO_0000115: Developmental defect characteristic of a particular organ or organ system which may be a recognised syndrome or a complex defect showing multiple manifestations.
has OBO namespace: mouse_pathology.ontology
id: MPATH:86

cardiovascular developmental defect
type: Class
subclass of: organ specific developmental defect
IAO_0000115: Abnormal development of the heart or vascular tissue resulting in morphological abnormality.
has OBO namespace: mouse_pathology.ontology
id: MPATH:89

aneurysm
type: Class
subclass of: developmental or adult structural defect
IAO_0000115: Localised dilation of an artery or heart chamber usually due to an acquired or congenital weakness of the wall of the artery or chamber.
has OBO namespace: mouse_pathology.ontology
id: MPATH:90

dissecting aneurysm
type: Class
subclass of: aneurysm
IAO_0000115: Follows the presence of a hematoma in the wall of an artery Splitting of the media occurs, blood enters the split through a tear in the intima.
has OBO namespace: mouse_pathology.ontology
id: MPATH:97

lymphangiectasis
type: Class
subclass of: ectasia
subclass of: cardiovascular developmental defect
IAO_0000115: A stretching and widening of the lymphatic vessels.
has OBO namespace: mouse_pathology.ontology
has related synonym: Lymphectasia
has related synonym: telangiectasia lymphatica
id: MPATH:98

High Grade Astrocytic Tumor
type: Class
subclass of: Malignant Glioma
subclass of: Astrocytic Tumor
IAO_0000115: An anaplastic astrocytoma (grade III astrocytic tumor) or glioblastoma (grade IV astrocytic tumor).
has exact synonym: High Grade Astrocytic Neoplasm
has exact synonym: High Grade Astrocytic Tumor
has exact synonym: High-Grade Astrocytic Neoplasm
has exact synonym: High-Grade Astrocytic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C102897

Malignant Cardiovascular Neoplasm
type: Class
subclass of: Cardiovascular Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the cardiovascular system.
has exact synonym: Malignant Cardiovascular Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C114940

Germinomatous Germ Cell Tumor
type: Class
subclass of: Germ Cell Tumor
IAO_0000115: A term that refers to germinoma, seminoma, or dysgerminoma.
has exact synonym: Germinomatous Germ Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C121618

Nongerminomatous Germ Cell Tumor
type: Class
subclass of: Germ Cell Tumor
IAO_0000115: A term that refers to teratoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, or mixed forms of these tumors.
has exact synonym: Nongerminomatous Germ Cell Tumor
has exact synonym: Nongerminomatous Germ Cell Tumor Including Central Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C121619

Sarcomatoid Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Anaplastic Malignant Neoplasm
IAO_0000115: A malignant epithelial neoplasm characterized by the presence of spindle cells and anaplastic morphologic features. Giant cells and a sarcomatous component may also be present.
has exact synonym: CARCINOMA, SPINDLE CELL, MALIGNANT
has exact synonym: Pseudosarcomatous Carcinoma
has exact synonym: Sarcomatoid Carcinoma
has exact synonym: Spindle Cell Carcinoma
has exact synonym: sarcomatoid carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27004

Spindle Cell Sarcoma
type: Class
subclass of: Sarcoma
IAO_0000115: A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas.
has exact synonym: Spindle Cell Sarcoma
has exact synonym: spindle cell sarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27005

Hematopoietic and Lymphoid Cell Neoplasm
type: Class
subclass of: Hematopoietic and Lymphoid System Neoplasm
subclass of: Neoplasm by Morphology
IAO_0000115: A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes.
has exact synonym: Hematologic Cancer
has exact synonym: Hematologic Malignancy
has exact synonym: Hematologic Neoplasm
has exact synonym: Hematological Neoplasm
has exact synonym: Hematological Tumor
has exact synonym: Hematopoietic Cancer
has exact synonym: Hematopoietic Cell Tumor
has exact synonym: Hematopoietic Neoplasm
has exact synonym: Hematopoietic Neoplasms including Lymphomas
has exact synonym: Hematopoietic Tumor
has exact synonym: Hematopoietic and Lymphoid Cell Neoplasm
has exact synonym: Hematopoietic and Lymphoid Neoplasms
has exact synonym: Hematopoietic malignancy, NOS
has exact synonym: Hematopoietic, Including Myeloma
has exact synonym: Malignant Hematologic Neoplasm
has exact synonym: Malignant Hematopoietic Neoplasm
has exact synonym: hematologic cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27134

Histiocytic Sarcoma
type: Class
subclass of: Histiocytic and Dendritic Cell Neoplasm
IAO_0000115: An aggressive malignant neoplasm with a poor response to therapy, usually presenting as stage III/IV disease. It is characterized by the presence of neoplastic cells with morphologic and immunophenotypic characteristics similar to those seen in mature histiocytes.
has exact synonym: Histiocytic Sarcoma
has exact synonym: SARCOMA, HISTIOCYTIC, MALIGNANT
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27349

Childhood Liver and Intrahepatic Bile Duct Neoplasm
type: Class
subclass of: Childhood Neoplasm
subclass of: Liver and Intrahepatic Bile Duct Neoplasm
IAO_0000115: A benign or malignant neoplasm of the liver parenchyma and intrahepatic bile ducts that occurs during childhood.
has exact synonym: Childhood Hepatic Neoplasm
has exact synonym: Childhood Liver Neoplasm
has exact synonym: Childhood Liver and Intrahepatic Bile Duct Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27368

Thyroid Gland Adenocarcinoma
type: Class
subclass of: Adenocarcinoma
subclass of: Malignant Endocrine Neoplasm
subclass of: Thyroid Gland Carcinoma
subclass of: Common Carcinoma
IAO_0000115: An adenocarcinoma arising from the follicular cells of the thyroid gland. According to the degree of differentiation, it is classified either as differentiated carcinoma (extensive evidence of follicular cell differentiation), or poorly differentiated carcinoma (limited evidence of follicular cell differentiation).
has exact synonym: Thyroid Adenocarcinoma
has exact synonym: Thyroid Gland Adenocarcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27380

Benign Hair Follicle Neoplasm
type: Class
subclass of: Benign Skin Appendage Neoplasm
subclass of: Hair Follicle Neoplasm
IAO_0000115: A neoplasm that arises from the hair follicle and does not metastasize to other anatomic sites.
has exact synonym: Benign Follicular Neoplasm
has exact synonym: Benign Follicular Tumor
has exact synonym: Benign Hair Follicle Neoplasm
has exact synonym: Benign Hair Follicle Tumor
has exact synonym: HAIR FOLLICLE NEOPLASM, BENIGN
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27520

Bile Duct Adenocarcinoma
type: Class
subclass of: Bile Duct Carcinoma
subclass of: Adenocarcinoma
IAO_0000115: An adenocarcinoma that arises from the intrahepatic bile ducts, the hepatic ducts, or the extrahepatic bile ducts. Adenocarcinomas that arise from the intrahepatic bile ducts or the hepatic ducts are called cholangiocarcinomas.
has exact synonym: Bile Duct Adenocarcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27813

Bile Duct Carcinoma
type: Class
subclass of: Bile Duct Neoplasm
subclass of: Malignant Hepatobiliary Neoplasm
subclass of: Digestive System Carcinoma
IAO_0000115: A malignant tumor arising from the epithelium of the intrahepatic or extrahepatic bile duct. Carcinomas that arise from the intrahepatic bile ducts and the hepatic ducts are called cholangiocarcinomas and are almost always adenocarcinomas. Carcinomas that arise from the extrahepatic bile ducts are adenocarcinomas, adenosquamous carcinomas, squamous cell carcinomas, small cell carcinomas, or mucoepidermoid carcinomas.
has exact synonym: Bile Duct Cancer
has exact synonym: Bile Duct Carcinoma
has exact synonym: bile duct cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27814

B-Cell Neoplasm
type: Class
subclass of: Lymphocytic Neoplasm
has exact synonym: B-Cell Lymphocytic Neoplasm
has exact synonym: B-Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27907

T-Cell and NK-Cell Neoplasm
type: Class
subclass of: Lymphocytic Neoplasm
has exact synonym: T-Cell Neoplasm
has exact synonym: T-Cell and NK-Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27908

Mature B-Cell Neoplasm
type: Class
subclass of: B-Cell Neoplasm
IAO_0000115: A neoplasm that arises from mature B-lymphocytes or plasma cells. Representative examples include mature B-cell non-Hodgkin lymphomas, chronic lymphocytic leukemia, hairy cell leukemia, and plasma cell neoplasms.
has exact synonym: Mature B-Cell Lymphocytic Neoplasm
has exact synonym: Mature B-Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C27910

Adenocarcinoma
type: Class
subclass of: Carcinoma
subclass of: Glandular Cell Neoplasm
IAO_0000115: A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma.
has exact synonym: ADENOCARCINOMA, MALIGNANT
has exact synonym: Adenocarcinoma
has exact synonym: Adenocarcinoma, NOS
has exact synonym: adenocarcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2852

Papillary Adenocarcinoma
type: Class
subclass of: Adenocarcinoma
subclass of: Papillary Carcinoma
IAO_0000115: A morphologic variant of adenocarcinoma. It is characterized by the presence of a papillary growth pattern. Representative examples include thyroid gland papillary carcinoma, invasive papillary breast carcinoma, and ovarian serous surface papillary adenocarcinoma.
has exact synonym: ADENOCARCINOMA, PAPILLARY, MALIGNANT
has exact synonym: Papillary Adenocarcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2853

Adenoma
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract.
has exact synonym: ADENOMA, BENIGN
has exact synonym: Adenoma
has exact synonym: adenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2855

Adrenal Gland Neoplasm
type: Class
subclass of: Retroperitoneal Neoplasm
IAO_0000115: A benign or malignant (primary or metastatic) neoplasm affecting the adrenal glands.
has exact synonym: Adrenal Gland Neoplasm
has exact synonym: Adrenal Gland Tumor
has exact synonym: Adrenal Neoplasm
has exact synonym: Adrenal Neoplasms
has exact synonym: Adrenal Tumor
has exact synonym: Neoplasm of Adrenal Gland
has exact synonym: Neoplasm of the Adrenal Gland
has exact synonym: Tumor of Adrenal Gland
has exact synonym: Tumor of the Adrenal Gland
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2859

Benign Skin Neoplasm
type: Class
subclass of: Skin Neoplasm
IAO_0000115: Abnormal growth of the cells that comprise the tissues of the skin, without any evidence of malignancy.
has exact synonym: Benign Cutaneous Neoplasm
has exact synonym: Benign Cutaneous Tumor
has exact synonym: Benign Neoplasm of Skin
has exact synonym: Benign Neoplasm of the Skin
has exact synonym: Benign Skin Neoplasm
has exact synonym: Benign Skin Tumor
has exact synonym: Benign Tumor of Skin
has exact synonym: Benign Tumor of the Skin
has exact synonym: Skin Neoplasms, Benign
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2896

Bile Duct Neoplasm
type: Class
subclass of: Hepatobiliary Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the intrahepatic or extrahepatic bile ducts. Representative examples of benign neoplasms include bile duct adenoma and extrahepatic bile duct lipoma. Representative examples of malignant neoplasms include intrahepatic and extrahepatic cholangiocarcinoma.
has exact synonym: Bile Duct Neoplasm
has exact synonym: Bile Duct Tumor
has exact synonym: Intrahepatic and Extrahepatic Bile Duct Neoplasm
has exact synonym: Intrahepatic and Extrahepatic Bile Duct Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2898

Brain Neoplasm
type: Class
subclass of: Intracranial Neoplasm
IAO_0000115: A benign or malignant neoplasm that arises from or metastasizes to the brain.
has exact synonym: Brain Neoplasm
has exact synonym: Brain Neoplasms
has exact synonym: Brain Tumor
has exact synonym: Brain tumor
has exact synonym: Neoplasm of Brain
has exact synonym: Neoplasm of the Brain
has exact synonym: Tumor of Brain
has exact synonym: Tumor of the Brain
has exact synonym: brain tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2907

Breast Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males.
has exact synonym: Breast Neoplasm
has exact synonym: Breast Tumor
has exact synonym: Neoplasm of Breast
has exact synonym: Neoplasm of the Breast
has exact synonym: Neoplasm, Breast
has exact synonym: Tumor of Breast
has exact synonym: Tumor of the Breast
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2910

Carcinoma
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas.
has exact synonym: CARCINOMA, MALIGNANT
has exact synonym: Carcinoma
has exact synonym: Carcinoma, NOS
has exact synonym: Epithelial Carcinoma
has exact synonym: Epithelioma Malignant
has exact synonym: Malignant Epithelial Neoplasm
has exact synonym: Malignant Epithelial Tumor
has exact synonym: Malignant Epithelioma
has exact synonym: carcinoma
has exact synonym: epithelial carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2916

Malignant Skin Neoplasm
type: Class
subclass of: Skin Neoplasm
IAO_0000115: A primary or metastatic tumor involving the skin. Primary malignant skin tumors most often are carcinomas (either basal cell or squamous cell carcinomas that arise from cells in the epidermis) or melanomas that arise from pigment-containing skin melanocytes. Metastatic tumors to the skin include carcinomas and lymphomas.
has exact synonym: Malignant Neoplasm of Skin
has exact synonym: Malignant Neoplasm of the Skin
has exact synonym: Malignant Skin Neoplasm
has exact synonym: Malignant Skin Tumor
has exact synonym: Malignant Tumor of Skin
has exact synonym: Malignant Tumor of the Skin
has exact synonym: Melanoma and Non-Melanoma Skin Cancer
has exact synonym: Skin Cancer
has exact synonym: Skin Cancer, Including Melanoma
has exact synonym: Skin Neoplasm, Malignant
has exact synonym: Skin cancer, NOS
has exact synonym: skin cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2920

Skin Basal Cell Carcinoma
type: Class
subclass of: Skin Carcinoma
subclass of: Malignant Basal Cell Neoplasm
subclass of: Common Carcinoma
IAO_0000115: The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas.
has exact synonym: BCC
has exact synonym: Basal Cell Cancer
has exact synonym: Basal Cell Carcinoma
has exact synonym: Basal Cell Carcinoma of Skin
has exact synonym: Basal Cell Carcinoma of the Skin
has exact synonym: Basal Cell Epithelioma
has exact synonym: Basal Cell Skin Carcinoma
has exact synonym: Basal cell carcinoma
has exact synonym: Skin Basal Cell Carcinoma
has exact synonym: basal cell cancer
has exact synonym: basal cell carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2921

Non-Small Cell Lung Carcinoma
type: Class
subclass of: Lung Carcinoma
subclass of: Non-Small Cell Carcinoma
subclass of: Common Carcinoma
IAO_0000115: A group of at least three distinct histological types of lung cancer, including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.
has exact synonym: NSCLC
has exact synonym: NSCLC - Non-Small Cell Lung Cancer
has exact synonym: Non Small Cell Lung Cancer NOS
has exact synonym: Non-Small Cell Cancer of Lung
has exact synonym: Non-Small Cell Cancer of the Lung
has exact synonym: Non-Small Cell Carcinoma of Lung
has exact synonym: Non-Small Cell Carcinoma of the Lung
has exact synonym: Non-Small Cell Lung Cancer
has exact synonym: Non-Small Cell Lung Carcinoma
has exact synonym: Non-small cell lung cancer, NOS
has exact synonym: non-small cell lung cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2926

Papillary Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Papillary Epithelial Neoplasm
IAO_0000115: A malignant epithelial neoplasm characterized by a papillary growth pattern. A papillary carcinoma may be composed of glandular cells (papillary adenocarcinoma), squamous cells (papillary squamous cell carcinoma), or transitional cells (papillary transitional cell carcinoma). Bladder carcinoma is a representative example of papillary transitional cell carcinoma.
has exact synonym: Papillary Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2927

Squamous Cell Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Squamous Cell Neoplasm
IAO_0000115: A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma.
has exact synonym: CARCINOMA, SQUAMOUS CELL, MALIGNANT
has exact synonym: Epidermoid Carcinoma
has exact synonym: Epidermoid Cell Cancer
has exact synonym: Malignant Epidermoid Cell Neoplasm
has exact synonym: Malignant Epidermoid Cell Tumor
has exact synonym: Malignant Squamous Cell Neoplasm
has exact synonym: Malignant Squamous Cell Tumor
has exact synonym: Squamous Carcinoma
has exact synonym: Squamous Cell Cancer
has exact synonym: Squamous Cell Carcinoma
has exact synonym: Squamous Cell Epithelioma
has exact synonym: epidermoid carcinoma
has exact synonym: squamous cell carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2929

Transitional Cell Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Transitional Cell Neoplasm
IAO_0000115: A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries.
has exact synonym: CARCINOMA, UROTHELIAL, MALIGNANT
has exact synonym: Transitional Carcinoma
has exact synonym: Transitional Cell Carcinoma
has exact synonym: transitional cell carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2930

Cerebellar Neoplasm
type: Class
subclass of: Infratentorial Neoplasm
IAO_0000115: A benign or malignant (primary or metastatic) tumor involving the cerebellum. -- 2003
has exact synonym: Cerebellar Neoplasm
has exact synonym: Cerebellar Tumor
has exact synonym: Neoplasm of Cerebellum
has exact synonym: Neoplasm of the Cerebellum
has exact synonym: Tumor of Cerebellum
has exact synonym: Tumor of the Cerebellum
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2935

Intraventricular Brain Neoplasm
type: Class
subclass of: Brain Neoplasm
IAO_0000115: A neoplasm that involves a brain ventricle. It may be a primary neoplasm arising from a brain ventricle, a metastasis from a distant anatomic site, or an extension of an invasive neoplasm from an adjacent brain structure.
has exact synonym: Brain Neoplasms, Intraventricular
has exact synonym: Intraventricular Brain Neoplasm
has exact synonym: Intraventricular Brain Neoplasms
has exact synonym: Intraventricular Brain Tumor
has exact synonym: Intraventricular Neoplasm of Brain
has exact synonym: Intraventricular Neoplasm of the Brain
has exact synonym: Intraventricular Neoplasms
has exact synonym: Intraventricular Tumor of Brain
has exact synonym: Intraventricular Tumor of the Brain
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2937

Chondrosarcoma
type: Class
subclass of: Chondrogenic Neoplasm
subclass of: Sarcoma
IAO_0000115: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.
has exact synonym: CHONDROSARCOMA, MALIGNANT
has exact synonym: Chondrosarcoma
has exact synonym: chondrosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2946

Chordoma
type: Class
subclass of: Malignant Bone Neoplasm
subclass of: Notochordal Tumor
IAO_0000115: A malignant bone tumor arising from the remnants of the fetal notochord. Although it can occur at all ages, it is more frequently seen in middle-aged adults. The most frequent sites of involvement are the sacrococcygeal area, spheno-occipital area, and cervico-thoraco-lumbar spine. Microscopically, chordomas are composed of cells that form cords and lobules, separated by mucoid intercellular tissue. Some of the cells are large (physaliphorous) and have vacuolated cytoplasm and prominent vesicular nuclei. Other tumor cells are small with small nuclei without visible nucleoli. Chordomas tend to recur and may metastasize. The most common sites of metastasis are the skin and bone.
has exact synonym: CHORDOMA, MALIGNANT
has exact synonym: Chordoma
has exact synonym: chordoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2947

Colorectal Neoplasm
type: Class
subclass of: Intestinal Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the colon or rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colorectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.
has exact synonym: Colorectal Neoplasm
has exact synonym: Colorectal Tumor
has exact synonym: Large Bowel Neoplasm
has exact synonym: Large Bowel Tumor
has exact synonym: Large Intestinal Neoplasm
has exact synonym: Large Intestine Neoplasm
has exact synonym: Large Intestine Tumor
has exact synonym: Neoplasm of Large Bowel
has exact synonym: Neoplasm of the Large Bowel
has exact synonym: Tumor of Large Bowel
has exact synonym: Tumor of the Large Bowel
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2956

Cystadenoma
type: Class
subclass of: Cystic Neoplasm
subclass of: Glandular Cell Neoplasm
IAO_0000115: A benign or borderline cystic epithelial neoplasm arising from the glandular epithelium. The epithelial cells line the cystic spaces which contain serous or mucinous fluid. Representative examples include ovarian and pancreatic cystadenomas.
has exact synonym: CYSTADENOMA, BENIGN
has exact synonym: Cystadenoma
has exact synonym: Cystoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2972

Papillary Cystadenoma
type: Class
subclass of: Cystadenoma
subclass of: Papillary Cystic Neoplasm
IAO_0000115: A serous or mucinous benign or low malignant potential cystic epithelial neoplasm. It is characterized by the presence of glandular epithelial cells forming papillary structures.
has exact synonym: CYSTADENOMA, PAPILLARY, BENIGN
has exact synonym: Papillary Cystadenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2974

Dysgerminoma
type: Class
subclass of: Germinomatous Germ Cell Tumor
subclass of: Malignant Germ Cell Tumor
IAO_0000115: A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage.
has exact synonym: DYSGERMINOMA, MALIGNANT
has exact synonym: Dysgerminoma
has exact synonym: dysgerminoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C2996

Endocrine Neoplasm
type: Class
subclass of: Neoplasm by Site
subclass of: Epithelial Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma.
has exact synonym: Endocrine Neoplasm
has exact synonym: Endocrine System Neoplasm
has exact synonym: Endocrine System Tumor
has exact synonym: Endocrine Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3010

Ependymoma
type: Class
subclass of: Ependymal Tumor
IAO_0000115: A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)
has exact synonym: Ependymoma
has exact synonym: Ependymoma, NOS
has exact synonym: WHO Grade II Ependymal Neoplasm
has exact synonym: WHO Grade II Ependymal Tumor
has exact synonym: ependymoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3017

Eye Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant neoplasm affecting the structures of the eye.
has exact synonym: Eye Neoplasm
has exact synonym: Eye Tumor
has exact synonym: Neoplasm of Eye
has exact synonym: Neoplasm of the Eye
has exact synonym: Ocular Neoplasm
has exact synonym: Ocular Tumor
has exact synonym: Tumor of Eye
has exact synonym: Tumor of the Eye
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3030

Fibroma
type: Class
subclass of: Fibroblastic Neoplasm
IAO_0000115: A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts.
has exact synonym: FIBROMA, BENIGN
has exact synonym: Fibroma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3041

Fibromatosis
type: Class
subclass of: Fibroblastic Neoplasm
IAO_0000115: A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern.
has exact synonym: Fibromatosis
has exact synonym: fibromatosis
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3042

Fibrosarcoma
type: Class
subclass of: Fibroblastic Neoplasm
subclass of: Sarcoma
IAO_0000115: A malignant mesenchymal fibroblastic neoplasm affecting the soft tissue and bone.
has exact synonym: FIBROSARCOMA, MALIGNANT
has exact synonym: Fibrosarcoma
has exact synonym: Fibrosarcoma (excluding infantile fibrosarcoma)
has exact synonym: Fibrosarcoma - not infantile
has exact synonym: Malignant Fibromatous Neoplasm
has exact synonym: fibrosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3043

Ganglioneuroma
type: Class
subclass of: Autonomic Nervous System Neoplasm
subclass of: Neuroblastic Tumor
IAO_0000115: A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray.
has exact synonym: GANGLIONEUROMA, BENIGN
has exact synonym: Ganglioneuroma
has exact synonym: Ganglioneuroma (Schwannian Stroma-Dominant)
has exact synonym: Neural Crest Tumor, Benign
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3049

Digestive System Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant neoplasm involving any part of the digestive system.
has exact synonym: Digestive Neoplasm
has exact synonym: Digestive System Neoplasm
has exact synonym: Digestive System Tumor
has exact synonym: Digestive Tumor
has exact synonym: GI Neoplasm
has exact synonym: GI System Neoplasm
has exact synonym: GI System Tumor
has exact synonym: GI Tumor
has exact synonym: Gastrointestinal Neoplasm
has exact synonym: Gastrointestinal System Neoplasm
has exact synonym: Gastrointestinal System Tumor
has exact synonym: Gastrointestinal Tumor
has exact synonym: Neoplasm of Digestive System
has exact synonym: Neoplasm of GI System
has exact synonym: Neoplasm of Gastrointestinal System
has exact synonym: Neoplasm of the Digestive System
has exact synonym: Neoplasm of the GI System
has exact synonym: Neoplasm of the Gastrointestinal System
has exact synonym: Tumor of Digestive System
has exact synonym: Tumor of GI System
has exact synonym: Tumor of Gastrointestinal System
has exact synonym: Tumor of the Digestive System
has exact synonym: Tumor of the GI System
has exact synonym: Tumor of the Gastrointestinal System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3052

Glioblastoma
type: Class
subclass of: High Grade Astrocytic Tumor
subclass of: Anaplastic Malignant Neoplasm
IAO_0000115: The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma). (WHO)
has exact synonym: GBM
has exact synonym: GBM (Glioblastoma)
has exact synonym: Glioblastoma
has exact synonym: Glioblastoma Multiforme
has exact synonym: Glioblastoma multiforme
has exact synonym: Grade IV Astrocytic Neoplasm
has exact synonym: Grade IV Astrocytic Tumor
has exact synonym: Spongioblastoma Multiforme
has exact synonym: glioblastoma
has exact synonym: glioblastoma multiforme
has exact synonym: grade IV astrocytoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3058

Glioma
type: Class
subclass of: Neuroepithelial Neoplasm
IAO_0000115: A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas.
has exact synonym: Glial Neoplasm
has exact synonym: Glial Tumor
has exact synonym: Glioma
has exact synonym: Neoplasm of Neuroglia
has exact synonym: Neoplasm of the Neuroglia
has exact synonym: Neuroglial Neoplasm
has exact synonym: Neuroglial Tumor
has exact synonym: Tumor of Neuroglia
has exact synonym: Tumor of the Neuroglia
has exact synonym: glial tumor
has exact synonym: glioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3059

Head and Neck Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant neoplasm that affects the anatomic structures of the head and neck region. Representative examples of benign neoplasms include salivary gland pleomorphic adenoma and nasal cavity papilloma. Representative examples of malignant neoplasms include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma.
has exact synonym: Head and Neck Neoplasm
has exact synonym: Head and Neck Neoplasm (Excluding Central Nervous System)
has exact synonym: Head and Neck Tumor
has exact synonym: Neoplasm of Head and Neck
has exact synonym: Neoplasm of the Head and Neck
has exact synonym: Tumor of Head and Neck
has exact synonym: Tumor of the Head and Neck
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3077

Hemangioma
type: Class
subclass of: Benign Blood Vessel Neoplasm
IAO_0000115: A benign vascular lesion characterized by the formation of capillary-sized or cavernous vascular channels.
has exact synonym: Angioma
has exact synonym: Benign Angioma
has exact synonym: Benign Hemangioma
has exact synonym: HEMANGIOMA, BENIGN
has exact synonym: Hemangioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3085

Cavernous Hemangioma
type: Class
subclass of: Hemangioma
IAO_0000115: A hemangioma characterized by the presence of cavernous vascular spaces.
has exact synonym: Cavernoma
has exact synonym: Cavernous Angioma
has exact synonym: Cavernous Hemangioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3086

Angiosarcoma
type: Class
subclass of: Malignant Blood Vessel Neoplasm
subclass of: Sarcoma
IAO_0000115: A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma.
has exact synonym: Angiosarcoma
has exact synonym: HEMANGIOSARCOMA, MALIGNANT
has exact synonym: Hemangiosarcoma
has exact synonym: Malignant Angioendothelioma
has exact synonym: Malignant Hemangioendothelioma
has exact synonym: angiosarcoma
has exact synonym: hemangiosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3088

Hepatocellular Carcinoma
type: Class
subclass of: Adenocarcinoma
subclass of: Common Carcinoma
subclass of: Liver and Intrahepatic Bile Duct Carcinoma
IAO_0000115: A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.
has exact synonym: CARCINOMA, HEPATOCELLULAR, MALIGNANT
has exact synonym: Carcinoma of Liver Cells
has exact synonym: Carcinoma of the Liver Cells
has exact synonym: HCC
has exact synonym: Hepatocellular Carcinoma
has exact synonym: Hepatocellular carcinoma
has exact synonym: Hepatoma
has exact synonym: Liver Cell Cancer (Hepatocellular Carcinoma)
has exact synonym: Liver Cell Carcinoma
has exact synonym: Primary Carcinoma of Liver Cells
has exact synonym: Primary Carcinoma of the Liver Cells
has exact synonym: hepatocellular carcinoma
has exact synonym: hepatoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3099

Infratentorial Neoplasm
type: Class
subclass of: Brain Neoplasm
IAO_0000115: A benign or malignant neoplasm that occurs in brain parenchymal tissue below the tentorium cerebelli.
has exact synonym: Brain Neoplasms, Infratentorial
has exact synonym: Infratentorial Neoplasm
has exact synonym: Infratentorial Neoplasms
has exact synonym: Infratentorial Tumor
has exact synonym: Infratentorial Tumors
has exact synonym: Neoplasms, Infratentorial
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3139

Intestinal Neoplasm
type: Class
subclass of: Digestive System Neoplasm
IAO_0000115: A benign or malignant neoplasm involving the small or large intestine.
has exact synonym: Intestinal Neoplasm
has exact synonym: Intestinal Neoplasms
has exact synonym: Intestinal Tumor
has exact synonym: Intestinal Tumors
has exact synonym: Neoplasm of Intestines
has exact synonym: Neoplasm of the Intestines
has exact synonym: Tumor of Intestines
has exact synonym: Tumor of the Intestines
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3141

Kidney Neoplasm
type: Class
subclass of: Kidney and Ureter Neoplasm
IAO_0000115: A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.
has exact synonym: Kidney Neoplasm
has exact synonym: Kidney Tumor
has exact synonym: Neoplasm of Kidney
has exact synonym: Neoplasm of the Kidney
has exact synonym: Renal Neoplasm
has exact synonym: Renal Tumor
has exact synonym: Renal Tumors
has exact synonym: Tumor of Kidney
has exact synonym: Tumor of the Kidney
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3150

Leiomyoma
type: Class
subclass of: Benign Smooth Muscle Neoplasm
IAO_0000115: A well-circumscribed benign smooth muscle neoplasm characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.
has exact synonym: Fibroid
has exact synonym: Fibroid Neoplasm
has exact synonym: Fibroid Tumor
has exact synonym: LEIOMYOMA, BENIGN
has exact synonym: Leiomyoma
has exact synonym: Leiomyomatous Neoplasm
has exact synonym: Leiomyomatous Tumor
has exact synonym: fibroid
has exact synonym: leiomyoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3157

Leiomyosarcoma
type: Class
subclass of: Malignant Smooth Muscle Neoplasm
subclass of: Sarcoma
IAO_0000115: An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas.
has exact synonym: LEIOMYOSARCOMA, MALIGNANT
has exact synonym: Leiomyosarcoma
has exact synonym: Leiomyosarcoma (excluding uterine leiomyosarcoma)
has exact synonym: Leiomyosarcoma - not uterine
has exact synonym: Leiomyosarcomas
has exact synonym: leiomyosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3158

Leydig Cell Tumor
type: Class
subclass of: Sex Cord-Stromal Tumor
IAO_0000115: A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.
has exact synonym: Interstitial Cell Neoplasm
has exact synonym: Interstitial Cell Tumor
has exact synonym: Leydig Cell Neoplasm
has exact synonym: Leydig Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3188

Lipoma
type: Class
subclass of: Benign Lipomatous Neoplasm
IAO_0000115: A benign, usually painless, well-circumscribed lipomatous tumor composed of adipose tissue.
has exact synonym: LIPOMA, BENIGN
has exact synonym: Lipoma
has exact synonym: lipoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3192

Lung Neoplasm
type: Class
subclass of: Respiratory Tract Neoplasm
subclass of: Thoracic Neoplasm
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma.
has exact synonym: Lung Neoplasm
has exact synonym: Lung Neoplasms
has exact synonym: Lung Tumor
has exact synonym: Neoplasm of Lung
has exact synonym: Neoplasm of the Lung
has exact synonym: Tumor of Lung
has exact synonym: Tumor of the Lung
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3200

Lymphoma
type: Class
subclass of: Lymphocytic Neoplasm
IAO_0000115: A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.
has exact synonym: LYMPHOMA, MALIGNANT
has exact synonym: Lymphoma
has exact synonym: Lymphoma (Hodgkin and Non-Hodgkin)
has exact synonym: Lymphoma (Hodgkin's and Non-Hodgkin's)
has exact synonym: Lymphoma, NOS
has exact synonym: Lymphomatous
has exact synonym: Malignant Lymphoma
has exact synonym: lymphoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3208

Malignant Retinal Neoplasm
type: Class
subclass of: Malignant Eye Neoplasm
subclass of: Retinal Neoplasm
IAO_0000115: Abnormal growth of cells comprising the retina with malignant characteristics.
has exact synonym: Malignant Neoplasm of Retina
has exact synonym: Malignant Neoplasm of the Retina
has exact synonym: Malignant Retina Neoplasm
has exact synonym: Malignant Retina Tumor
has exact synonym: Malignant Retinal Neoplasm
has exact synonym: Malignant Retinal Tumor
has exact synonym: Malignant Tumor of Retina
has exact synonym: Malignant Tumor of the Retina
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3216

Mediastinal Neoplasm
type: Class
subclass of: Thoracic Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the structures of the mediastinum. Representative examples include mediastinal lipoma, mediastinal schwannoma, thymoma, and mediastinal lymphoma.
has exact synonym: Mediastinal Neoplasm
has exact synonym: Mediastinal Neoplasm NOS
has exact synonym: Mediastinal Tumor
has exact synonym: Neoplasm of Mediastinum
has exact synonym: Neoplasm of the Mediastinum
has exact synonym: Tumor of Mediastinum
has exact synonym: Tumor of the Mediastinum
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3221

Medulloblastoma
type: Class
subclass of: Malignant Cerebellar Neoplasm
subclass of: Central Nervous System Embryonal Neoplasm
IAO_0000115: A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, large cell medulloblastoma, and medulloblastoma with extensive nodularity.
has exact synonym: MEDULLOBLASTOMA, MALIGNANT
has exact synonym: Medulloblastoma
has exact synonym: Medulloblastomas
has exact synonym: medulloblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3222

Melanoma
type: Class
subclass of: Melanocytic Neoplasm
IAO_0000115: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
has exact synonym: MELANOMA, MALIGNANT
has exact synonym: Malignant Melanoma
has exact synonym: Melanoma
has exact synonym: melanoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3224

Meningeal Neoplasm
type: Class
subclass of: Central Nervous System Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the meninges. The majority of the neoplasms arise from meningothelial cells and are called meningiomas. Non-meningothelial cell neoplasms include mesenchymal, non-meningothelial tumors, hemangiopericytomas, and melanocytic lesions.
has exact synonym: Meningeal Neoplasm
has exact synonym: Meningeal Neoplasms
has exact synonym: Meningeal Tumor
has exact synonym: Meninges Neoplasm
has exact synonym: Meninges Tumor
has exact synonym: Neoplasm of Meninges
has exact synonym: Neoplasm of the Meninges
has exact synonym: Tumor of Meninges
has exact synonym: Tumor of the Meninges
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3229

Meningioma
type: Class
subclass of: Meningeal Neoplasm
subclass of: Meningothelial Cell Neoplasm
IAO_0000115: A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)
has exact synonym: Meningioma
has exact synonym: Meningioma, NOS
has exact synonym: meningioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3230

Mesothelioma
type: Class
subclass of: Mesothelial Neoplasm
IAO_0000115: A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
has exact synonym: Mesothelioma
has exact synonym: mesothelioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3234

Neck Neoplasm
type: Class
subclass of: Head and Neck Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the neck region.
has exact synonym: Neck Neoplasm
has exact synonym: Neck Neoplasms (Including All Pharyngeal Related Neoplasms)
has exact synonym: Neck Tumor
has exact synonym: Neoplasm of Neck
has exact synonym: Neoplasm of the Neck
has exact synonym: Tumor of Neck
has exact synonym: Tumor of the Neck
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3260

Neoplasm
type: Class
IAO_0000115: A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias.
has exact synonym: Neoplasia
has exact synonym: Neoplasm
has exact synonym: Neoplastic Disease
has exact synonym: Neoplastic Growth
has exact synonym: neoplasia
has exact synonym: neoplasm
has exact synonym: tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3262

Neoplasm by Site
type: Class
subclass of: Neoplasm
IAO_0000115: A term that refers to the classification of a neoplastic process according to the anatomic site that is involved.
has exact synonym: Neoplasm by Site
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3263

Embryonal Neoplasm
type: Class
subclass of: Neoplasm by Special Category
IAO_0000115: A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003
has exact synonym: Embryonal Neoplasm
has exact synonym: embryonal tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3264

Wilms Tumor
type: Class
subclass of: Embryonal Neoplasm
subclass of: Malignant Mixed Neoplasm
IAO_0000115: An embryonal neoplasm characterized by the presence of epithelial, mesenchymal, and blastema components. The vast majority of cases arise from the kidney. A small number of cases with morphologic features resembling Wilms tumor of the kidney have been reported arising from the ovary and the cervix.
has exact synonym: Wilms Tumor
has exact synonym: Wilms tumor
has exact synonym: Wilms tumor (Nephroblastoma)
has exact synonym: Wilms' Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3267

Nervous System Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the central or peripheral nervous system.
has exact synonym: Neoplasm of Nervous System
has exact synonym: Neoplasm of the Nervous System
has exact synonym: Nervous System Neoplasm
has exact synonym: Nervous System Neoplasms
has exact synonym: Nervous System Tumor
has exact synonym: Nervous System Tumour
has exact synonym: Tumor of Nervous System
has exact synonym: Tumor of the Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3268

Schwannoma
type: Class
subclass of: Nerve Sheath Neoplasm
IAO_0000115: A benign, usually encapsulated slow growing tumor composed of Schwann cells. It affects peripheral and cranial nerves. It recurs infrequently and only rare cases associated with malignant transformation have been reported.
has exact synonym: Benign Neurilemmoma
has exact synonym: Benign Schwannoma
has exact synonym: Neurilemmoma
has exact synonym: Neurinoma
has exact synonym: SCHWANNOMA, BENIGN
has exact synonym: Schwannoma
has exact synonym: Schwannoma (WHO Grade I)
has exact synonym: Schwannoma (Who Grade I)
has exact synonym: schwannoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3269

Neuroblastoma
type: Class
subclass of: Neuroblastic Tumor
IAO_0000115: A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.
has exact synonym: NEUROBLASTOMA, MALIGNANT
has exact synonym: Neural Crest Tumor, Malignant
has exact synonym: Neuroblastoma
has exact synonym: Neuroblastoma (Schwannian Stroma-Poor)
has exact synonym: Neuroblastoma (Schwannian Stroma-poor)
has exact synonym: neuroblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3270

Neurofibroma
type: Class
subclass of: Peripheral Nervous System Neoplasm
subclass of: Nerve Sheath Neoplasm
IAO_0000115: An intraneural or extraneural neoplasm arising from nerve tissues and neural sheaths. It is composed of perineurial-like fibroblasts and Schwann cells. It usually presents as a localized cutaneous lesion and less often as a circumscribed peripheral nerve mass. Patients with neurofibromatosis type 1 present with multiple masses. Neurofibromas which arise from major nerves and plexiform neurofibromas are precursor lesions to malignant peripheral nerve sheath tumors.
has exact synonym: NEUROFIBROMA, BENIGN
has exact synonym: Neurofibroma
has exact synonym: Neurofibroma (WHO Grade I)
has exact synonym: neurofibroma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3272

Odontogenic Neoplasm
type: Class
subclass of: Infrequent Neoplasm
subclass of: Oral Cavity Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from tooth-forming tissues. It occurs in the maxillofacial skeleton or the gingiva. Benign tumors are slow growing and are not associated with specific clinical symptoms. Pain is absent or slight. Malignant tumors are usually associated with rapid swelling and pain.
has exact synonym: Odontogenic Neoplasm
has exact synonym: Odontogenic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3286

Oligodendroglioma
type: Class
subclass of: Oligodendroglial Tumor
IAO_0000115: A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO)
has exact synonym: Oligodendroglioma
has exact synonym: Oligodendroglioma, NOS
has exact synonym: WHO Grade II Oligodendroglial Neoplasm
has exact synonym: WHO Grade II Oligodendroglial Tumor
has exact synonym: Well Differentiated Oligodendroglial Tumor
has exact synonym: Well Differentiated Oligodendroglioma
has exact synonym: oligodendroglioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3288

Osteoma
type: Class
subclass of: Benign Bone Neoplasm
subclass of: Benign Osteogenic Neoplasm
IAO_0000115: A benign, well-circumscribed, bone-forming neoplasm predominantly composed of lamellar bone. It usually arises from the calvarial, facial, or jaw bones. It is usually asymptomatic but it may cause local swelling or obstruction of the paranasal sinuses. Asymptomatic cases have an indolent clinical course.
has exact synonym: OSTEOMA, BENIGN
has exact synonym: Osteoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3296

Paraganglioma
type: Class
subclass of: Neuroendocrine Neoplasm
subclass of: Autonomic Nervous System Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases.
has exact synonym: Neoplasm of Paraganglion
has exact synonym: Neoplasm of the Paraganglion
has exact synonym: Paraganglioma
has exact synonym: Paraganglion Neoplasm
has exact synonym: Paraganglion Tumor
has exact synonym: Paraganglionic Neoplasm
has exact synonym: Paraganglionic Tumor
has exact synonym: Tumor of Paraganglion
has exact synonym: Tumor of the Paraganglion
has exact synonym: paraganglioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3308

Peripheral Nervous System Neoplasm
type: Class
subclass of: Nervous System Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths.
has exact synonym: CNS-excluded nervous sys. cancer
has exact synonym: CNS-excluded nervous system cancer, NOS
has exact synonym: Neoplasm of PNS
has exact synonym: Neoplasm of Peripheral Nerve
has exact synonym: Neoplasm of Peripheral Nervous System
has exact synonym: Neoplasm of the PNS
has exact synonym: Neoplasm of the Peripheral Nerve
has exact synonym: Neoplasm of the Peripheral Nervous System
has exact synonym: Neoplasms, PNS
has exact synonym: Neoplasms, Peripheral Nervous System
has exact synonym: PNS Neoplasm
has exact synonym: PNS Neoplasms
has exact synonym: PNS Tumor
has exact synonym: Peripheral Nerve Neoplasm
has exact synonym: Peripheral Nerve Tumor
has exact synonym: Peripheral Nervous System Neoplasm
has exact synonym: Peripheral Nervous System Tumor
has exact synonym: Tumor of PNS
has exact synonym: Tumor of Peripheral Nerve
has exact synonym: Tumor of Peripheral Nervous System
has exact synonym: Tumor of the PNS
has exact synonym: Tumor of the Peripheral Nerve
has exact synonym: Tumor of the Peripheral Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3321

Adrenal Gland Pheochromocytoma
type: Class
subclass of: Sympathetic Paraganglioma
subclass of: Adrenal Medulla Neoplasm
IAO_0000115: A benign or malignant neuroendocrine neoplasm of the sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the adrenal medulla. Clinical presentation includes headaches, palpitations, chest and abdominal pain, hypertension, fever, and tremor. Microscopically, a characteristic nesting (zellballen) growth pattern is usually seen. Other growth patterns including trabecular pattern may also be present.
has exact synonym: Adrenal Gland Chromaffin Paraganglioma
has exact synonym: Adrenal Gland Chromaffinoma
has exact synonym: Adrenal Gland Paraganglioma
has exact synonym: Adrenal Gland Pheochromocytoma
has exact synonym: Adrenal Medullary Paraganglioma
has exact synonym: Adrenal Medullary Pheochromocytoma
has exact synonym: Adrenal Pheochromocytoma
has exact synonym: Chromaffin Paraganglioma of the Adrenal Gland
has exact synonym: Intraadrenal Paraganglioma
has exact synonym: PCC
has exact synonym: Pheochromocytoma
has exact synonym: Pheochromocytoma (adrenal)
has exact synonym: pheochromocytoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3326

Pineal Region Neoplasm
type: Class
subclass of: Supratentorial Neoplasm
IAO_0000115: Neoplasms that are located in the pineal gland. These neoplasms arise either from pineal parenchymal cells (pineocytes), as do pineocytomas and the more aggressive pineoblastomas, or from other cell types, as do pineal astrocytic tumors (notably pilocytic astrocytomas) and germ cell tumors. Clinical symptoms include neuro-ophthalmologic dysfunction, changes in mental status, dysfunction of the brain stem, and hypothalamic-based endocrine abnormalities.
has exact synonym: Neoplasm of Pineal Area
has exact synonym: Neoplasm of Pineal Region
has exact synonym: Neoplasm of the Pineal Area
has exact synonym: Neoplasm of the Pineal Region
has exact synonym: Pineal Area Neoplasm
has exact synonym: Pineal Area Tumor
has exact synonym: Pineal Body Neoplasm
has exact synonym: Pineal Body Tumor
has exact synonym: Pineal Neoplasm
has exact synonym: Pineal Region Neoplasm
has exact synonym: Pineal Region Tumor
has exact synonym: Pineal Tumor
has exact synonym: Pinealoma
has exact synonym: Tumor of Pineal Area
has exact synonym: Tumor of Pineal Region
has exact synonym: Tumor of the Pineal Area
has exact synonym: Tumor of the Pineal Region
has exact synonym: pineal region tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3328

Familial Adenomatous Polyposis
type: Class
subclass of: Multiple Adenomatous Polyps
subclass of: Colorectal Adenomatous Polyp
IAO_0000115: An autosomal dominant disorder, characterized by the presence of multiple adenomas in the colon and rectum. It is caused by a germline mutation in the adenomatous polyposis coli (APC) gene which is located on the long arm of chromosome 5. The adenomas are most often tubular, and they have the tendency to progress to adenocarcinoma. They can occur throughout the colon, but they tend to concentrate in the rectum and sigmoid colon. The colorectal adenomas are detected during endoscopic examination between the age of 10 and 20 years. The adenomas increase in size and numbers with age, and there is usually progression of one or more adenomas to adenocarcinoma. The mean age of development of adenocarcinoma is about 40 years. Signs include rectal bleeding and mucousy diarrhea.
has exact synonym: APC - Adenomatous Polyposis Coli
has exact synonym: Adenomatous Polyposis Coli
has exact synonym: FAP
has exact synonym: Familial Adenomatous Polyposis
has exact synonym: Familial Adenomatous Polyposis Coli
has exact synonym: Familial Adenomatous Polyposis Syndrome
has exact synonym: Hereditary Adenomatous Polyposis Coli
has exact synonym: Polyposis Coli
has exact synonym: familial adenomatous polyposis
has exact synonym: familial polyposis
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3339

Respiratory Tract Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the respiratory tract.
has exact synonym: Neoplasm of Respiratory Tract
has exact synonym: Neoplasm of the Respiratory Tract
has exact synonym: Respiratory Tract Neoplasm
has exact synonym: Respiratory Tract Tumor
has exact synonym: Tumor of Respiratory Tract
has exact synonym: Tumor of the Respiratory Tract
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3355

Retroperitoneal Neoplasm
type: Class
subclass of: Peritoneal and Retroperitoneal Neoplasms
IAO_0000115: A benign or malignant neoplasm that affects the retroperitoneum.
has exact synonym: Retroperitoneal Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3357

Rhabdomyoma
type: Class
subclass of: Benign Muscle Neoplasm
IAO_0000115: A benign mesenchymal tumor arising from skeletal or cardiac muscle.
has exact synonym: RHABDOMYOMA, BENIGN
has exact synonym: Rhabdomyoma
has exact synonym: Rhabdomyomatous Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3358

Rhabdomyosarcoma
type: Class
subclass of: Malignant Skeletal Muscle Neoplasm
subclass of: Infrequent Neoplasm
subclass of: Sarcoma NCI Grade 3
IAO_0000115: A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites.
has exact synonym: RHABDOMYOSARCOMA, MALIGNANT
has exact synonym: Rhabdomyosarcoma
has exact synonym: Rhabdomyosarcoma, NOS
has exact synonym: rhabdomyosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3359

Skin Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.
has exact synonym: Neoplasm of Skin
has exact synonym: Neoplasm of the Skin
has exact synonym: Skin Neoplasm
has exact synonym: Skin Neoplasms
has exact synonym: Skin Tumor
has exact synonym: Tumor of Skin
has exact synonym: Tumor of the Skin
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3372

Soft Tissue Neoplasm
type: Class
subclass of: Connective and Soft Tissue Neoplasm
IAO_0000115: A benign, intermediate, or malignant neoplasm that arises from the soft tissue. The most common types are lipomatous (fatty), vascular, smooth muscle, fibrous, and fibrohistiocytic neoplasms.
has exact synonym: Neoplasm of Soft Tissue
has exact synonym: Neoplasm of the Soft Tissue
has exact synonym: Soft Tissue Neoplasm
has exact synonym: Soft Tissue Tumor
has exact synonym: Soft Tissue Tumors
has exact synonym: Soft tissue neoplasm, NOS
has exact synonym: Tumor of Soft Tissue
has exact synonym: Tumor of the Soft Tissue
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3377

Supratentorial Neoplasm
type: Class
subclass of: Brain Neoplasm
IAO_0000115: A benign or malignant neoplasm that occurs within the intracranial cavity above the tentorium cerebelli.
has exact synonym: Brain Neoplasms, Supratentorial
has exact synonym: Supratentorial Neoplasm
has exact synonym: Supratentorial Neoplasms
has exact synonym: Supratentorial Tumor
has exact synonym: Supratentorial Tumors
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3397

Teratoma
type: Class
subclass of: Nongerminomatous Germ Cell Tumor
IAO_0000115: A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, teratomas are classified as mature or immature. Mature teratomas are composed of well differentiated, adult-type tissues. Immature teratomas are composed of immature, fetal-type tissues. Testicular teratomas in children follow a benign clinical course. Mature ovarian teratomas without a fetal-type component have an excellent outcome. The prognosis of immature ovarian teratomas is related to the grade and stage of the tumor.
has exact synonym: Teratoma
has exact synonym: teratoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3403

Thoracic Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the tissues of the thorax.
has exact synonym: Neoplasm of Thorax
has exact synonym: Neoplasm of the Thorax
has exact synonym: Thoracic Neoplasm
has exact synonym: Thoracic Tumor
has exact synonym: Tumor of Thorax
has exact synonym: Tumor of the Thorax
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3406

Thymoma
type: Class
subclass of: Thymus Epithelial Neoplasm
IAO_0000115: A neoplasm arising from the epithelial cells of the thymus. Although thymomas are usually encapsulated tumors, they may invade the capsule and infiltrate the surrounding tissues or even metastasize to distant anatomic sites. The following morphologic subtypes are currently recognized: type A, type B, type AB, metaplastic, micronodular, microscopic, and sclerosing thymoma. Thymomas type B are further subdivided into types B1, B2, and B3. Thymoma type B3 usually has the most aggressive clinical course.
has exact synonym: Thymoma
has exact synonym: thymoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3411

Thyroid Gland Neoplasm
type: Class
subclass of: Neck Neoplasm
IAO_0000115: A benign or malignant neoplasm affecting the thyroid gland.
has exact synonym: Neoplasm of Thyroid
has exact synonym: Neoplasm of Thyroid Gland
has exact synonym: Neoplasm of the Thyroid
has exact synonym: Neoplasm of the Thyroid Gland
has exact synonym: Thyroid Gland Neoplasm
has exact synonym: Thyroid Gland Tumor
has exact synonym: Thyroid Neoplasm
has exact synonym: Thyroid Neoplasms
has exact synonym: Thyroid Tumor
has exact synonym: Tumor of Thyroid
has exact synonym: Tumor of Thyroid Gland
has exact synonym: Tumor of the Thyroid
has exact synonym: Tumor of the Thyroid Gland
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3414

Urinary System Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the urinary system. --2003
has exact synonym: Neoplasm of Urinary System
has exact synonym: Neoplasm of Urinary Tract
has exact synonym: Neoplasm of the Urinary System
has exact synonym: Neoplasm of the Urinary Tract
has exact synonym: Tumor of Urinary System
has exact synonym: Tumor of Urinary Tract
has exact synonym: Tumor of the Urinary System
has exact synonym: Tumor of the Urinary Tract
has exact synonym: Urinary System Neoplasm
has exact synonym: Urinary System Tumor
has exact synonym: Urinary Tract Neoplasm
has exact synonym: Urinary Tract Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3431

Choroid Plexus Neoplasm
type: Class
subclass of: Intraventricular Brain Neoplasm
subclass of: Epithelial Neoplasm
IAO_0000115: An intraventricular papillary neoplasm that originates from the choroid plexus epithelium. It includes the choroid plexus papilloma, atypical choroid plexus papilloma, and choroid plexus carcinoma.
has exact synonym: Choroid Plexus Neoplasm
has exact synonym: Choroid Plexus Tumor
has exact synonym: Neoplasm of Choroid Plexus
has exact synonym: Neoplasm of the Choroid Plexus
has exact synonym: Tumor of Choroid Plexus
has exact synonym: Tumor of the Choroid Plexus
has exact synonym: choroid plexus tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3473

Primary Malignant Liver Neoplasm
type: Class
subclass of: Liver and Intrahepatic Bile Duct Neoplasm
subclass of: Malignant Hepatobiliary Neoplasm
IAO_0000115: An epithelial or non-epithelial malignant neoplasm that arises from the liver. Representative examples include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, lymphoma, and sarcoma.
has exact synonym: Primary Malignant Liver Neoplasm
has exact synonym: Primary Malignant Neoplasm of Liver
has OBO namespace: mouse_pathology.ontology
id: NCIT:C34803

Cutaneous Melanoma
type: Class
subclass of: Malignant Skin Neoplasm
subclass of: Melanoma
subclass of: Melanocytic Skin Neoplasm
IAO_0000115: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma.
has exact synonym: Cutaneous Melanoma
has exact synonym: Malignant Cutaneous Melanoma
has exact synonym: Malignant Melanoma (of Skin), Stage Unspecified
has exact synonym: Malignant Melanoma of Skin
has exact synonym: Malignant Melanoma of Skin Stage Unspecified
has exact synonym: Melanoma of Skin
has exact synonym: Melanoma of the Skin
has exact synonym: Skin Melanoma
has exact synonym: Skin, Melanoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3510

Malignant Mediastinal Neoplasm
type: Class
subclass of: Mediastinal Neoplasm
subclass of: Malignant Thoracic Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the mediastinum. Representative examples of primary malignant mediastinal neoplasms include malignant germ cell tumors, malignant mesenchymal tumors, lymphomas, and malignant peripheral nerve sheath tumors. A representative example of metastatic malignant neoplasm to the mediastinum is the metastatic carcinoma to the mediastinum from another anatomic site.
has exact synonym: Cancer of Mediastinum
has exact synonym: Cancer of the Mediastinum
has exact synonym: Malignant Mediastinal Neoplasm
has exact synonym: Malignant Mediastinal Neoplasm NOS
has exact synonym: Malignant Mediastinal Tumor
has exact synonym: Malignant Neoplasm of Mediastinum
has exact synonym: Malignant Neoplasm of the Mediastinum
has exact synonym: Malignant Tumor of Mediastinum
has exact synonym: Malignant Tumor of the Mediastinum
has exact synonym: Mediastinal Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3549

Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
type: Class
subclass of: Nervous System Neoplasm
subclass of: Neoplasm by Morphology
IAO_0000115: A morphologic category that includes neoplasms arising from cells that form and support the nervous system. Such neoplasms include neuroepithelial cell neoplasms and neoplasms that arise from the perineural sheaths (perineurial cell neoplasms and Schwann cell neoplasms). --2003
has exact synonym: Neural Neoplasm
has exact synonym: Neural Tumor
has exact synonym: Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C35562

Malignant Brain Neoplasm
type: Class
subclass of: Brain Neoplasm
subclass of: Malignant Intracranial Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the brain.
has exact synonym: Brain Cancer
has exact synonym: Brain Neoplasms, Malignant
has exact synonym: Cancer of Brain
has exact synonym: Cancer of the Brain
has exact synonym: Malignant Brain Neoplasm
has exact synonym: Malignant Brain Tumor
has exact synonym: Malignant Neoplasm of Brain
has exact synonym: Malignant Neoplasm of the Brain
has exact synonym: Malignant Tumor of Brain
has exact synonym: Malignant Tumor of the Brain
has exact synonym: Malignant neoplasm of brain
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3568

Malignant Cerebellar Neoplasm
type: Class
subclass of: Cerebellar Neoplasm
subclass of: Malignant Infratentorial Neoplasm
IAO_0000115: Primary and secondary (metastatic) malignant tumors that occur in the cerebellum. Histologic types include medulloblastomas, high grade (WHO Stage III or IV) cerebellar astrocytomas, lymphomas, gangliogliomas, gliosarcomas, and several other subtypes. The most frequent malignant cerebellar neoplasm of childhood is medulloblastoma. In adults, metastases from other sites are relatively common. Clinical features include ataxia, headache, nausea, dizzyness, nystagmus, diplopia, papilledema, etc.
has exact synonym: Cancer of Cerebellum
has exact synonym: Cancer of the Cerebellum
has exact synonym: Cerebellar Cancer
has exact synonym: Cerebellar Neoplasm, Malignant
has exact synonym: Cerebellar Tumor, Malignant
has exact synonym: Malignant Cerebellar Neoplasm
has exact synonym: Malignant Cerebellar Neoplasms
has exact synonym: Malignant Cerebellar Tumor
has exact synonym: Malignant Neoplasm of Cerebellum
has exact synonym: Malignant Neoplasm of the Cerebellum
has exact synonym: Malignant Tumor of Cerebellum
has exact synonym: Malignant Tumor of the Cerebellum
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3569

Malignant Endocrine Neoplasm
type: Class
subclass of: Endocrine Neoplasm
IAO_0000115: A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma.
has exact synonym: Endocrine Neoplasm, Malignant
has exact synonym: Endocrine cancer, NOS
has exact synonym: Malignant Endocrine Gland Neoplasm
has exact synonym: Malignant Endocrine Gland Tumor
has exact synonym: Malignant Endocrine Neoplasm
has exact synonym: Malignant Endocrine Tumor
has exact synonym: Malignant Neoplasm of Endocrine Gland
has exact synonym: Malignant Neoplasm of the Endocrine Gland
has exact synonym: Malignant Tumor of Endocrine Gland
has exact synonym: Malignant Tumor of the Endocrine Gland
has exact synonym: endocrine cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3575

Malignant Thoracic Neoplasm
type: Class
subclass of: Thoracic Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the tissues of the thorax.
has exact synonym: Malignant Neoplasm of Thorax
has exact synonym: Malignant Neoplasm of the Thorax
has exact synonym: Malignant Thoracic Neoplasm
has exact synonym: Malignant Thoracic Tumor
has exact synonym: Malignant Tumor of Thorax
has exact synonym: Malignant Tumor of the Thorax
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3576

Hematopoietic and Lymphoid System Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003
has exact synonym: Hematopoietic and Lymphoid System Neoplasm
has exact synonym: Hematopoietic and Lymphoid System Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C35813

Head and Neck Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Malignant Head and Neck Neoplasm
IAO_0000115: A carcinoma that arises from the head and neck region. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma.
has exact synonym: Carcinoma of Head and Neck
has exact synonym: Carcinoma of the Head and Neck
has exact synonym: Head and Neck Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C35850

Anaplastic Malignant Neoplasm
type: Class
subclass of: Malignant Neoplasm
has exact synonym: Anaplastic Malignant Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C36025

Papillary Neoplasm
type: Class
subclass of: Neoplasm by Special Category
has exact synonym: Papillary Neoplasm
has exact synonym: Papillary Tumor
has exact synonym: papillary tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C36031

Digestive System Adenoma
type: Class
subclass of: Adenoma
subclass of: Digestive System Neoplasm
IAO_0000115: A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.
has exact synonym: Digestive System Adenoma
has exact synonym: GI Adenoma
has exact synonym: Gastrointestinal Adenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C36207

Reproductive System Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm affecting the male and female reproductive system.
has exact synonym: Neoplasm of Reproductive System
has exact synonym: Neoplasm of the Reproductive System
has exact synonym: Reproductive Neoplasm
has exact synonym: Reproductive System Neoplasm
has exact synonym: Reproductive System Tumor
has exact synonym: Reproductive Tumor
has exact synonym: Tumor of Reproductive System
has exact synonym: Tumor of the Reproductive System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3674

Choroid Plexus Papilloma
type: Class
subclass of: Papilloma
subclass of: Benign Choroid Plexus Neoplasm
IAO_0000115: A benign, slow growing tumor which may cause symptoms by blocking cerebrospinal fluid pathways. It is characterized by the presence of delicate fibrovascular connective tissue fronds covered by a single layer of epithelial cells. Mitotic activity is extremely low. Surgical resection is usually curative. (Adapted from WHO)
has exact synonym: Choroid Plexus Papilloma
has exact synonym: PAPILLOMA, CHOROID PLEXUS, BENIGN
has exact synonym: Papilloma of Choroid Plexus
has exact synonym: Papilloma of the Choroid Plexus
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3698

Germ Cell Tumor
type: Class
subclass of: Neoplasm by Morphology
IAO_0000115: A benign or malignant, gonadal or extragonadal neoplasm that originates from germ cells. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor.
has exact synonym: Germ Cell Neoplasm
has exact synonym: Germ Cell Tumor
has exact synonym: Neoplasm of Germ Cell
has exact synonym: Neoplasm of the Germ Cell
has exact synonym: Tumor of Germ Cell
has exact synonym: Tumor of the Germ Cell
has exact synonym: germ cell tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3708

Epithelial Neoplasm
type: Class
subclass of: Neoplasm by Morphology
IAO_0000115: A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas.
has exact synonym: Epithelial Neoplasm
has exact synonym: Epithelial Neoplasms, NOS
has exact synonym: Epithelioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3709

Primitive Neuroectodermal Tumor
type: Class
subclass of: Embryonal Neoplasm
subclass of: Neuroepithelial Neoplasm
IAO_0000115: A malignant neoplasm that originates in the neuroectoderm. The neuroectoderm constitutes the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems and includes some glial cell precursors.
has exact synonym: Neuroectodermal Neoplasm
has exact synonym: Neuroectodermal Tumor
has exact synonym: Neuroepithelioma
has exact synonym: PNET
has exact synonym: Primitive Neuroectodermal Neoplasm
has exact synonym: Primitive Neuroectodermal Tumor
has exact synonym: neuroectodermal tumor
has exact synonym: primitive neuroectodermal tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3716

Lymphatic Vessel Neoplasm
type: Class
subclass of: Vascular Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from the lymphatic vessels.
has exact synonym: Lymph Vessel Neoplasm
has exact synonym: Lymph Vessel Tumor
has exact synonym: Lymphatic Vessel Neoplasm
has exact synonym: Lymphatic Vessel Tumor
has exact synonym: Neoplasm of Lymph Vessel
has exact synonym: Neoplasm of Lymphatic Vessel
has exact synonym: Neoplasm of the Lymph Vessel
has exact synonym: Neoplasm of the Lymphatic Vessel
has exact synonym: Tumor of Lymph Vessel
has exact synonym: Tumor of Lymphatic Vessel
has exact synonym: Tumor of the Lymph Vessel
has exact synonym: Tumor of the Lymphatic Vessel
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3723

Hepatoblastoma
type: Class
subclass of: Embryonal Neoplasm
subclass of: Childhood Malignant Liver Neoplasm
IAO_0000115: A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.
has exact synonym: HBL
has exact synonym: HEPATOBLASTOMA, MALIGNANT
has exact synonym: Hepatoblastoma
has exact synonym: Pediatric Embryonal Hepatoma
has exact synonym: Pediatric Hepatoblastoma
has exact synonym: hepatoblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3728

Malignant Mixed Neoplasm
type: Class
subclass of: Mixed Neoplasm
IAO_0000115: A malignant neoplasm composed of a carcinomatous epithelial component and a sarcomatous mesenchymal component. Representative examples include malignant mixed mesodermal (Mullerian) tumor of the female reproductive system and carcinosarcoma of the salivary gland and the lung.
has exact synonym: MIXED TUMOR, MALIGNANT
has exact synonym: Malignant Mixed Neoplasm
has exact synonym: Malignant Mixed Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3729

Pulmonary Blastoma
type: Class
subclass of: Lung Sarcomatoid Carcinoma
subclass of: Blastoma
IAO_0000115: A malignant neoplasm of the lung composed of tubular structures and immature mesenchymal elements, which may differentiate towards skeletal and smooth muscle, cartilage or a combination of muscle and cartilage. This is a nodular tumor found in the periphery of the lung. It can occur at any age. The prognosis is related to the stage of the disease at the time of resection. Pulmonary blastoma is divided into two subtypes: epithelial predominant and biphasic.
has exact synonym: Blastoma of Lung
has exact synonym: Blastoma of the Lung
has exact synonym: Lung Blastoma
has exact synonym: Pneumoblastoma
has exact synonym: Pulmonary Blastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3732

Angiolipoma
type: Class
subclass of: Lipoma
IAO_0000115: A lipoma with prominent vascularity. The vascular tissue is more abundant at the periphery of the tumor and contains fibrin thrombi. It occurs more frequently in younger individuals as a painful subcutaneous nodule, often on the arms.
has exact synonym: ANGIOLIPOMA, BENIGN
has exact synonym: Angiolipoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3733

Angiomyolipoma
type: Class
subclass of: PEComa
IAO_0000115: A neoplasm with perivascular epithelioid cell differentiation often associated with tuberous sclerosis. It is characterized by a mixture of epithelioid cells, smooth muscle, vessels, and mature adipose tissue. The kidney is the most common site of involvement. Other sites of involvement include the liver, lung, lymph nodes, and retroperitoneum. The vast majority of cases follow a benign clinical course. However, cases of metastatic angiomyolipomas with sarcomatoid features have been described.
has exact synonym: Angiomyolipoma
has exact synonym: angiomyolipoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3734

Fibroepithelial Neoplasm
type: Class
subclass of: Mixed Neoplasm
IAO_0000115: A benign, borderline, or malignant neoplasm characterized by the presence of an epithelial and a fibrous component. Representative examples are fibroadenoma and phyllodes tumor.
has exact synonym: Fibroepithelial Neoplasm
has exact synonym: Fibroepithelial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3743

Fibroadenoma
type: Class
subclass of: Breast Fibroepithelial Neoplasm
IAO_0000115: A benign tumor of the breast characterized by the presence of stromal and epithelial elements. It presents as a painless, solitary, slow growing, firm, and mobile mass. It is the most common benign breast lesion. It usually occurs in women of childbearing age. The majority of fibroadenomas do not recur after complete excision. A slightly increased risk of developing cancer within fibroadenomas or in the breast tissue of patients previously treated for fibroadenomas has been reported.
has exact synonym: Breast Fibroadenoma
has exact synonym: FIBROADENOMA, BENIGN
has exact synonym: Fibroadenoma
has exact synonym: Fibroadenoma of Breast
has exact synonym: Fibroadenoma of the Breast
has exact synonym: fibroadenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3744

Alveolar Rhabdomyosarcoma
type: Class
subclass of: Rhabdomyosarcoma
subclass of: Sarcoma Differentiation Score 3
IAO_0000115: A rapidly growing malignant mesenchymal neoplasm. It is characterized by the presence of round cells with myoblastic differentiation and a fibrovascular stroma resembling an alveolar growth pattern. The tumor usually presents in the extremities.
has exact synonym: ARMS
has exact synonym: Alveolar Rhabdomyosarcoma
has exact synonym: Alveolar rhabdomyosarcoma
has exact synonym: Monomorphous Round Cell Rhabdomyosarcoma
has exact synonym: alveolar rhabdomyosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3749

Smooth Muscle Neoplasm
type: Class
subclass of: Myomatous Neoplasm
IAO_0000115: A benign or malignant myomatous neoplasm arising from smooth muscle.
has exact synonym: Neoplasm of Smooth Muscle
has exact synonym: Neoplasm of the Smooth Muscle
has exact synonym: Smooth Muscle Neoplasm
has exact synonym: Smooth Muscle Tumor
has exact synonym: Tumor of Smooth Muscle
has exact synonym: Tumor of the Smooth Muscle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3751

Gonadoblastoma
type: Class
subclass of: Mixed Germ Cell-Sex Cord-Stromal Tumor
IAO_0000115: A mixed germ cell/sex cord-stromal tumor characterized by the presence of large germ cells which resemble seminoma cells and small cells which resemble Sertoli or granulosa cells. It occurs in the testis and the ovary and is identified in children and adults. It is often associated with gonadal dysgenesis and abnormal karyotype.
has exact synonym: Gonadoblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3754

Mixed Embryonal Carcinoma and Teratoma
type: Class
subclass of: Nongerminomatous Germ Cell Tumor
subclass of: Mixed Germ Cell Tumor
IAO_0000115: A germ cell tumor characterized by the presence of an embryonal carcinoma component and a teratoma component.
has exact synonym: Mixed Embryonal Carcinoma and Teratoma
has exact synonym: Teratocarcinoma
has exact synonym: teratocarcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3756

Hepatocellular Adenoma
type: Class
subclass of: Adenoma
subclass of: Benign Liver and Intrahepatic Bile Duct Epithelial Neoplasm
IAO_0000115: A benign epithelial neoplasm arising from the hepatocytes. Grossly, it appears as a soft, round mass which often contains areas of hemorrhage and necrosis. Morphologically, the neoplastic cells resemble normal hepatocytes and form plates separated by sinusoids. Most patients have a history of contraceptive or anabolic steroids use.
has exact synonym: ADENOMA, HEPATOCELLULAR, BENIGN
has exact synonym: Adenoma of Liver Cells
has exact synonym: Adenoma of the Liver Cells
has exact synonym: HCA
has exact synonym: Hepatocellular Adenoma
has exact synonym: Liver Cell Adenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3758

Adenomatous Polyp
type: Class
subclass of: Adenoma
subclass of: Neoplastic Polyp
IAO_0000115: A polypoid neoplasm arising from the glandular epithelium. There is proliferation of glandular cells which may display dysplastic cytologic features. Representative examples include the adenomatous polyps of the colon and rectum.
has exact synonym: Adenomatous Polyp
has exact synonym: Polypoid Adenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3764

Neuroendocrine Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Malignant Endocrine Neoplasm
subclass of: Neuroendocrine Neoplasm
IAO_0000115: A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma.
has exact synonym: NEC
has exact synonym: Neuroendocrine Carcinoma
has exact synonym: Neuroendocrine cancer, NOS
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3773

Basal Cell Neoplasm
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: A neoplastic proliferation of basal cells in the epidermis (part of the skin) or other anatomic sites (most frequently the salivary glands). The basal cell neoplastic proliferation in the epidermis results in basal cell carcinomas. The basal cell neoplastic proliferation in the salivary glands can be benign, resulting in basal cell adenomas or malignant, resulting in basal cell adenocarcinomas.
has exact synonym: Basal Cell Neoplasm
has exact synonym: Basal Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3784

Mesothelial Neoplasm
type: Class
subclass of: Neoplasm by Morphology
IAO_0000115: A benign or malignant neoplasm arising from mesothelial cells. Mesothelial cells are the lining cells of the pleura and peritoneum. -- 2003
has exact synonym: Mesothelial Neoplasm
has exact synonym: Mesothelial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3786

Neuroepithelial Neoplasm
type: Class
subclass of: Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
IAO_0000115: A neoplasm of the nervous system that arises from the neuroepithelial tissues. Representative examples include astrocytic tumors, oligodendroglial tumors, ependymal tumors, and primitive neuroectodermal tumors.
has exact synonym: Neoplasm of Neuroepithelial Tissue
has exact synonym: Neoplasm of Neuroepithelium
has exact synonym: Neoplasm of the Neuroepithelium
has exact synonym: Neuroepithelial Neoplasm
has exact synonym: Neuroepithelial Neoplasms
has exact synonym: Neuroepithelial Tissue Neoplasm
has exact synonym: Neuroepithelial Tissue Tumor
has exact synonym: Neuroepithelial Tumor
has exact synonym: Neuroepithelial Tumors
has exact synonym: Tumor of Neuroepithelial Tissue
has exact synonym: Tumor of Neuroepithelium
has exact synonym: Tumor of the Neuroepithelium
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3787

Squamous Cell Neoplasm
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: A neoplasm that is composed of squamous epithelial cells. Squamous cell carcinoma is a representative example.
has exact synonym: Epidermoid Cell Neoplasm
has exact synonym: Epidermoid Cell Tumor
has exact synonym: Squamous Cell Neoplasm
has exact synonym: Squamous Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3792

Sex Cord-Stromal Tumor
type: Class
subclass of: Reproductive Endocrine Neoplasm
IAO_0000115: A neoplasm arising in the ovary or testis. It is composed of granulosa cells, Leydig cells, Sertoli cells, and fibroblasts. Each of these cell types may constitute the only cellular component that is present in the neoplasm or it may be mixed with other cell types in various combinations. The prognosis can not always be predicted on histologic grounds alone. Approximately, 10% of these tumors may metastasize. Representative examples include granulosa cell tumor, Leydig cell tumor, Sertoli cell tumor, and tumors of the thecoma-fibroma group.
has exact synonym: Sex Cord-Stromal Neoplasm
has exact synonym: Sex Cord-Stromal Tumor
has exact synonym: sex cord tumor
has exact synonym: sex cord-gonadal stromal tumor
has exact synonym: sex cord-stromal tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3794

Malignant Peripheral Nerve Sheath Tumor
type: Class
subclass of: Malignant Peripheral Nervous System Neoplasm
subclass of: Nerve Sheath Neoplasm
subclass of: Sarcoma
IAO_0000115: An uncommon, highly aggressive malignant tumor, arising from the peripheral nerves and affecting mostly adults in their third to sixth decades of life. It usually occurs in medium-sized and large nerves of the buttock, thigh, upper arm, or the paraspinal region. It may be associated with neurofibromatosis 1 (NF1).
has exact synonym: MPNST
has exact synonym: Malig. periph. nerve sheath tum.
has exact synonym: Malignant Neoplasm of Peripheral Nerve Sheath
has exact synonym: Malignant Neoplasm of the Peripheral Nerve Sheath
has exact synonym: Malignant Neurilemmoma
has exact synonym: Malignant Neurilemoma
has exact synonym: Malignant Peripheral Nerve Sheath Neoplasm
has exact synonym: Malignant Peripheral Nerve Sheath Tumor
has exact synonym: Malignant Peripheral Nerve Sheath Tumour
has exact synonym: Malignant Schwannoma
has exact synonym: Malignant Tumor of Peripheral Nerve Sheath
has exact synonym: Malignant Tumor of the Peripheral Nerve Sheath
has exact synonym: Malignant peripheral nerve sheath tumor
has exact synonym: Neurofibrosarcoma
has exact synonym: Neurofibrosarcoma, Malignant
has exact synonym: Neurogenic Sarcoma
has exact synonym: SCHWANNOMA, MALIGNANT
has exact synonym: malignant peripheral nerve sheath tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3798

Angiofibroma
type: Class
subclass of: Fibroma
subclass of: Benign Fibroblastic Neoplasm
IAO_0000115: A morphologic variant of fibroma characterized by the presence of numerous dilated vascular channels.
has exact synonym: ANGIOFIBROMA, BENIGN
has exact synonym: Angiofibroma
has exact synonym: Angiofibromatous Hyperplasia
has exact synonym: Fibroangioma, Benign
has exact synonym: Fibrous Papule
has exact synonym: Telangiectatic Fibroma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3799

Hemangioblastoma
type: Class
subclass of: Neoplasm of Uncertain Histogenesis
IAO_0000115: A WHO grade I tumor of uncertain histogenesis which is composed of stromal cells and abundant capillaries. Approximately 25% of hemangioblastomas are associated with Von Hippel-Lindau disease, a disease inherited through an autosomal dominant trait and characterized by the development of hemangioblastomas of the central nervous system and retina, clear cell renal carcinoma, pheochromocytoma, and pancreatic and inner ear tumors. (Adapted from WHO)
has exact synonym: Angioblastoma
has exact synonym: Capillary Hemangioblastoma
has exact synonym: Hemangioblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3801

Neuroendocrine Neoplasm
type: Class
subclass of: Endocrine Neoplasm
IAO_0000115: A benign or malignant neoplasm composed of cells of neuroendocrine origin. Representative examples include paraganglioma, carcinoid tumor, and neuroendocrine carcinoma.
has exact synonym: Neuroendocrine Neoplasm
has exact synonym: Neuroendocrine Tumor
has exact synonym: neuroendocrine tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3809

Connective and Soft Tissue Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign, intermediate, or malignant neoplasm that affects the connective and soft tissue.
has exact synonym: Connective and Soft Tissue Neoplasm
has exact synonym: Connective and Soft Tissue Tumor
has exact synonym: Musculoskeletal and Soft Tissue Neoplasm
has exact synonym: Musculoskeletal and Soft Tissue Tumor
has exact synonym: Neoplasm of Skeletal and Soft Tissue
has exact synonym: Neoplasm of Soft Tissue and Bone
has exact synonym: Neoplasm of Soft Tissue and Skeleton
has exact synonym: Skeletal and Soft Tissue Neoplasm
has exact synonym: Skeletal and Soft Tissue Tumor
has exact synonym: Soft Tissue and Bone Neoplasm
has exact synonym: Soft Tissue and Bone Tumor
has exact synonym: Tumor of Skeletal and Soft Tissue
has exact synonym: Tumor of Soft Tissue and Bone
has exact synonym: Tumor of Soft Tissue and Skeleton
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3810

PEComa
type: Class
subclass of: Soft Tissue Tumor of Uncertain Differentiation
IAO_0000115: A soft tissue mesenchymal tumor with perivascular epithelioid cell differentiation. Representative examples include angiomyolipoma, clear cell-sugar-tumor of the lung, and lymphangioleiomyomatosis.
has exact synonym: Neoplasm with Perivascular Epithelioid Cell Differentiation
has exact synonym: PEComa
has exact synonym: Tumor with Perivascular Epithelioid Cell Differentiation
has OBO namespace: mouse_pathology.ontology
id: NCIT:C38150

Thyroid Gland Medullary Carcinoma
type: Class
subclass of: Neuroendocrine Carcinoma
subclass of: Thyroid Gland Carcinoma
IAO_0000115: A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy.
has exact synonym: C Cell Carcinoma
has exact synonym: CARCINOMA, C-CELL, MALIGNANT
has exact synonym: MTC
has exact synonym: Medullary Carcinoma
has exact synonym: Medullary Carcinoma of Thyroid
has exact synonym: Medullary Carcinoma of Thyroid Gland
has exact synonym: Medullary Carcinoma of the Thyroid
has exact synonym: Medullary Carcinoma of the Thyroid Gland
has exact synonym: Medullary Thyroid Cancer
has exact synonym: Medullary Thyroid Carcinoma
has exact synonym: Medullary Thyroid Gland Carcinoma
has exact synonym: Medullary thyroid carcinoma
has exact synonym: Parafollicular Cell Carcinoma
has exact synonym: Thyroid Gland Medullary Carcinoma
has exact synonym: Thyroid Gland Neuroendocrine Carcinoma
has exact synonym: Thyroid Medullary Carcinoma
has exact synonym: medullary thyroid cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3879

Small Cell Carcinoma
type: Class
subclass of: Neuroendocrine Carcinoma
subclass of: Common Carcinoma
IAO_0000115: A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble "oat cells" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early.
has exact synonym: Oat Cell Cancer
has exact synonym: Oat Cell Carcinoma
has exact synonym: Small Cell Cancer
has exact synonym: Small Cell Carcinoma
has exact synonym: Small Cell NEC
has exact synonym: Small Cell Neuroendocrine Carcinoma
has exact synonym: Small cell car. (extrapulmonary)
has exact synonym: Small cell carcinoma (extrapulmonary)
has exact synonym: oat cell cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C3915

Sertoli Cell Tumor
type: Class
subclass of: Sex Cord-Stromal Tumor
IAO_0000115: A sex cord-stromal tumor of the testis or the ovary. It is characterized by the presence of Sertoli cells forming tubules. Leydig cells are rare or absent. It may be associated with Peutz-Jeghers syndrome. In males, the presenting symptom is a slow growing testicular mass. Most cases follow a benign clinical course. In females it may present with estrogenic or androgenic manifestations. The vast majority of cases have a benign clinical course.
has exact synonym: Sertoli Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C39976

Childhood Malignant Neoplasm
type: Class
subclass of: Childhood Neoplasm
subclass of: Malignant Neoplasm
IAO_0000115: A malignant tumor that occurs in children. Representative examples include soft tissue and bone sarcomas (e.g. osteosarcoma) and embryonal neoplasms (e.g. hepatoblastoma and rhabdoid tumor).
has exact synonym: Childhood Cancer
has exact synonym: Childhood Malignant Neoplasm
has exact synonym: Malignant Childhood Neoplasm
has exact synonym: Malignant Childhood Tumor
has exact synonym: Malignant Pediatric Neoplasm
has exact synonym: Malignant Pediatric Tumor
has exact synonym: Pediatric Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4005

Malignant Head and Neck Neoplasm
type: Class
subclass of: Head and Neck Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma.
has exact synonym: Cancer of Head and Neck
has exact synonym: Cancer of the Head and Neck
has exact synonym: Head and Neck Cancer
has exact synonym: Head and neck cancer, NOS
has exact synonym: Malignant Head and Neck Neoplasm
has exact synonym: Malignant Head and Neck Tumor
has exact synonym: Malignant Neoplasm of Head and Neck
has exact synonym: Malignant Neoplasm of the Head and Neck
has exact synonym: Malignant Tumor of Head and Neck
has exact synonym: Malignant Tumor of the Head and Neck
has exact synonym: head and neck cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4013

Malignant Bone Neoplasm
type: Class
subclass of: Bone Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the bone or articular cartilage.
has exact synonym: Bone Cancer
has exact synonym: Bone cancer
has exact synonym: Bone cancer, NOS
has exact synonym: Cancer of Bone
has exact synonym: Cancer of the Bone
has exact synonym: Malignant Bone Neoplasm
has exact synonym: Malignant Bone Tumor
has exact synonym: Malignant Neoplasm of Bone
has exact synonym: Malignant Neoplasm of the Bone
has exact synonym: Malignant Osseous Neoplasm
has exact synonym: Malignant Osseous Tumor
has exact synonym: Malignant Tumor of Bone
has exact synonym: Malignant Tumor of the Bone
has exact synonym: Osseous Cancer
has exact synonym: bone cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4016

Breast Fibroepithelial Neoplasm
type: Class
subclass of: Breast Neoplasm
subclass of: Fibroepithelial Neoplasm
IAO_0000115: A benign or malignant biphasic neoplasm that arises from the breast parenchyma. It is characterized by the presence of an epithelial and a mesenchymal (stromal) component. The typical examples are fibroadenoma and phyllodes tumor.
has exact synonym: Breast Fibroepithelial Neoplasm
has exact synonym: Breast Fibroepithelial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C40405

Kidney Wilms Tumor
type: Class
subclass of: Wilms Tumor
subclass of: Malignant Kidney Neoplasm
IAO_0000115: An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.
has exact synonym: Embryonal Nephroma
has exact synonym: Kidney Wilms Tumor
has exact synonym: NEPHROBLASTOMA, MALIGNANT
has exact synonym: Nephroblastoma
has exact synonym: Renal Wilms Tumor
has exact synonym: Renal Wilms' Tumor
has exact synonym: Wilms Tumor of the Kidney
has exact synonym: Wilms' Tumor of the Kidney
has exact synonym: Wilms' tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C40407

Myomatous Neoplasm
type: Class
subclass of: Mesenchymal Cell Neoplasm
IAO_0000115: A benign or malignant mesenchymal neoplasm arising from smooth, skeletal, or cardiac muscle.
has exact synonym: Muscle Neoplasm
has exact synonym: Muscle Tumor
has exact synonym: Myomatous Neoplasm
has exact synonym: Myomatous Tumor
has exact synonym: Neoplasm of Muscle
has exact synonym: Neoplasm of the Muscle
has exact synonym: Tumor of Muscle
has exact synonym: Tumor of the Muscle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4063

Polyposis
type: Class
subclass of: Neoplastic Polyp
has exact synonym: Multiple Polyps
has exact synonym: Polyposis
has exact synonym: polyposis
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4089

Benign Epithelial Neoplasm
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites.
has exact synonym: Benign Epithelial Neoplasm
has exact synonym: Benign Epithelial Tumor
has exact synonym: Benign Epithelioma
has exact synonym: Benign Neoplasm of Epithelium
has exact synonym: Benign Neoplasm of the Epithelium
has exact synonym: Benign Tumor of Epithelium
has exact synonym: Benign Tumor of the Epithelium
has exact synonym: EPITHELIOMA, BENIGN
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4092

Multiple Adenomatous Polyps
type: Class
subclass of: Adenomatous Polyp
subclass of: Polyposis
IAO_0000115: A condition in which multiple adenomas develop in the gastrointestinal tract.
has exact synonym: Multiple Adenomatous Polyps
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4135

Papillary Cystic Neoplasm
type: Class
subclass of: Cystic Neoplasm
subclass of: Papillary Epithelial Neoplasm
IAO_0000115: A benign, malignant, or borderline neoplasm characterized by the presence of papillary mucinous, serous, or clear cell structures and cystic structures.
has exact synonym: Papillary Cystic Neoplasm
has exact synonym: Papillary Cystic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4179

Sympathetic Paraganglioma
type: Class
subclass of: Paraganglioma
IAO_0000115: A benign or malignant paraganglioma arising from the chromaffin cells of the paraganglia that are located along the sympathetic nerves. It includes extra-adrenal paragangliomas and paragangliomas that arise from the adrenal medulla. The latter are commonly referred to as pheochromocytomas. Representative examples of extra-adrenal sympathetic paragangliomas include the bladder, and superior and inferior paraaortic paragangliomas. Clinical signs are related to the secretion of catecholamines resulting in hypertension.
has exact synonym: Chromaffin Neoplasm
has exact synonym: Chromaffin Tumor
has exact synonym: Chromaffinoma
has exact synonym: Sympathetic Paraganglioma
has exact synonym: Sympathetic Paraganglionic Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4216

Benign Soft Tissue Neoplasm
type: Class
subclass of: Soft Tissue Neoplasm
subclass of: Benign Connective and Soft Tissue Neoplasm
IAO_0000115: A non-metastasizing neoplasm that arises from the soft tissue.
has exact synonym: Benign Neoplasm of Soft Tissue
has exact synonym: Benign Neoplasm of the Soft Tissue
has exact synonym: Benign Soft Tissue Neoplasm
has exact synonym: Benign Soft Tissue Tumor
has exact synonym: Benign Tumor of Soft Tissue
has exact synonym: Benign Tumor of the Soft Tissue
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4242

Lipomatous Neoplasm
type: Class
subclass of: Mesenchymal Cell Neoplasm
IAO_0000115: A benign, intermediate, or malignant mesenchymal neoplasm composed of adipose (fatty) tissue.
has exact synonym: Adipose Tissue Neoplasm
has exact synonym: Adipose Tissue Tumor
has exact synonym: Lipomatous Neoplasm
has exact synonym: Lipomatous Tumor
has exact synonym: Neoplasm of Adipose Tissue
has exact synonym: Neoplasm of the Adipose Tissue
has exact synonym: Tumor of Adipose Tissue
has exact synonym: Tumor of the Adipose Tissue
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4248

Mixed Germ Cell Tumor
type: Class
subclass of: Malignant Germ Cell Tumor
IAO_0000115: A malignant germ cell tumor characterized by the presence of at least two different germ cell components. The different germ cell components include choriocarcinoma, embryonal carcinoma, yolk sac tumor, teratoma, and seminoma. It occurs in the ovary, testis, and extragonadal sites including central nervous system and mediastinum.
has exact synonym: Combined Germ Cell Neoplasm
has exact synonym: Combined Germ Cell Tumor
has exact synonym: Mixed Germ Cell Neoplasm
has exact synonym: Mixed Germ Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4290

Germinative Follicular Epithelium Neoplasm
type: Class
subclass of: Epithelial Skin Neoplasm
subclass of: Hair Follicle Neoplasm
has exact synonym: Germinative Follicular Epithelium Neoplasm
has exact synonym: Germinative Follicular Epithelium Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C43311

Benign Germinative Follicular Epithelium Neoplasm
type: Class
subclass of: Benign Hair Follicle Neoplasm
subclass of: Germinative Follicular Epithelium Neoplasm
subclass of: Benign Epithelial Skin Neoplasm
has exact synonym: Benign Germinative Follicular Epithelium Neoplasm
has exact synonym: Benign Germinative Follicular Epithelium Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C43319

Cholangiocarcinoma
type: Class
subclass of: Bile Duct Adenocarcinoma
IAO_0000115: A carcinoma that arises from the intrahepatic biliary tree (intrahepatic cholangiocarcinoma) or from the junction, or adjacent to the junction, of the right and left hepatic ducts (hilar cholangiocarcinoma). Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.
has exact synonym: CC
has exact synonym: CHOLANGIOCARCINOMA, MALIGNANT
has exact synonym: Cholangiocar.- intra/extrahepatic
has exact synonym: Cholangiocarcinoma
has exact synonym: Cholangiocarcinoma, intrahepatic and extrahepatic bile ducts (adenocarcinoma)
has exact synonym: Cholangiocellular Carcinoma
has exact synonym: cholangiocarcinoma
has exact synonym: cholangiosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4436

Skin Appendage Neoplasm
type: Class
subclass of: Skin Neoplasm
IAO_0000115: A benign or malignant neoplasm that arises from the hair follicles, sebaceous glands, or sweat glands.
has exact synonym: Adnexal Neoplasm of skin
has exact synonym: Adnexal Neoplasm of the skin
has exact synonym: Adnexal Tumor of skin
has exact synonym: Adnexal Tumor of the skin
has exact synonym: Cutaneous Adnexal Neoplasm
has exact synonym: Epidermal Appendage Neoplasm
has exact synonym: Epidermal Appendage Tumor
has exact synonym: Neoplasm of Epidermal Appendage
has exact synonym: Neoplasm of Skin Appendage
has exact synonym: Neoplasm of the Skin Appendage
has exact synonym: Skin Appendage Neoplasm
has exact synonym: Skin Appendage Tumor
has exact synonym: Tumor of Epidermal Appendage
has exact synonym: Tumor of Skin Appendage
has exact synonym: Tumor of the Skin Appendage
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4463

Benign Lipomatous Neoplasm
type: Class
subclass of: Lipomatous Neoplasm
subclass of: Benign Connective and Soft Tissue Neoplasm
IAO_0000115: A benign mesenchymal neoplasm composed of adipose (fatty) tissue. The most common representative of this category is the lipoma.
has exact synonym: Benign Adipose Tissue Neoplasm
has exact synonym: Benign Adipose Tissue Tumor
has exact synonym: Benign Lipomatous Neoplasm
has exact synonym: Benign Lipomatous Tumor
has exact synonym: Benign Neoplasm of Adipose Tissue
has exact synonym: Benign Neoplasm of the Adipose Tissue
has exact synonym: Benign Tumor of Adipose Tissue
has exact synonym: Benign Tumor of the Adipose Tissue
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4502

Lung Sarcomatoid Carcinoma
type: Class
subclass of: Sarcomatoid Carcinoma
subclass of: Non-Small Cell Lung Carcinoma
IAO_0000115: A rare, aggressive, poorly differentiated, non-small cell lung carcinoma characterized by the presence of a sarcomatoid component often associated with giant cell differentiation. There is a male to female ratio of 4:1. Clinical symptoms include cough, hemoptysis, chest pain, progressive dyspnea and fever secondary to recurrent pneumonia. Cigarette smoking is a major risk factor.
has exact synonym: Lung Sarcomatoid Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C45540

Malignant Respiratory Tract Neoplasm
type: Class
subclass of: Respiratory Tract Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm that affects the lung parenchyma, bronchial tree, or trachea. Representative examples include lung carcinoma, carcinoid tumor, lung lymphoma, lung sarcoma, and tracheal carcinoma.
has exact synonym: Malignant Neoplasm of Respiratory Tract
has exact synonym: Malignant Neoplasm of the Respiratory Tract
has exact synonym: Malignant Respiratory Tract Neoplasm
has exact synonym: Malignant Respiratory Tract Tumor
has exact synonym: Malignant Tumor of Respiratory Tract
has exact synonym: Malignant Tumor of the Respiratory Tract
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4571

Benign Skin Appendage Neoplasm
type: Class
subclass of: Benign Skin Neoplasm
subclass of: Skin Appendage Neoplasm
IAO_0000115: A non-metastasizing neoplasm that arises from the hair follicles, sebaceous glands, or sweat glands. Representative examples include cylindroma, hidrocystoma, hidradenoma, and sebaceoma.
has exact synonym: Benign Cutaneous Adnexal Neoplasm
has exact synonym: Benign Epidermal Appendage Neoplasm
has exact synonym: Benign Epidermal Appendage Tumor
has exact synonym: Benign Neoplasm of Epidermal Appendage
has exact synonym: Benign Neoplasm of the Epidermal Appendage
has exact synonym: Benign Skin Appendage Neoplasm
has exact synonym: Benign Tumor of Epidermal Appendage
has exact synonym: Benign Tumor of the Epidermal Appendage
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4615

Malignant Central Nervous System Neoplasm
type: Class
subclass of: Malignant Nervous System Neoplasm
subclass of: Central Nervous System Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the brain or spinal cord. Representative examples include anaplastic astrocytoma, glioblastoma, anaplastic (malignant) meningioma, lymphoma, and metastatic carcinoma from another anatomic site.
has exact synonym: CNS Cancer
has exact synonym: CNS Malignant Neoplasms
has exact synonym: CNS Neoplasms, Malignant
has exact synonym: Cancer of CNS
has exact synonym: Cancer of Central Nervous System
has exact synonym: Cancer of the CNS
has exact synonym: Cancer of the Central Nervous System
has exact synonym: Central Nervous System Cancer
has exact synonym: Central Nervous System Neoplasms, Malignant
has exact synonym: Malignant CNS Neoplasm
has exact synonym: Malignant CNS Neoplasms
has exact synonym: Malignant CNS Tumor
has exact synonym: Malignant Central Nervous System Neoplasm
has exact synonym: Malignant Central Nervous System Tumor
has exact synonym: Malignant Neoplasm of CNS
has exact synonym: Malignant Neoplasm of Central Nervous System
has exact synonym: Malignant Neoplasm of the CNS
has exact synonym: Malignant Neoplasm of the Central Nervous System
has exact synonym: Malignant Tumor of CNS
has exact synonym: Malignant Tumor of Central Nervous System
has exact synonym: Malignant Tumor of the CNS
has exact synonym: Malignant Tumor of the Central Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4627

Plasma Cell Neoplasm
type: Class
subclass of: Mature B-Cell Neoplasm
IAO_0000115: A clonal proliferation of immunoglobulin-secreting plasma cells. This category includes plasma cell myeloma, plasma cell leukemia, plasmacytoma, monoclonal immunoglobulin deposition disease, and monoclonal gammopathy of undetermined significance.
has exact synonym: PLASMA CELL TUMOR, MALIGNANT
has exact synonym: Plasma Cell Dyscrasia
has exact synonym: Plasma Cell Neoplasm
has exact synonym: Plasma Cell Tumor
has exact synonym: Plasmacytic Neoplasm
has exact synonym: Plasmacytic Tumor
has exact synonym: Plasmacytic Tumour
has exact synonym: plasma cell tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4665

Neoplasm by Morphology
type: Class
subclass of: Neoplasm
IAO_0000115: A classification system grouping neoplasms according to their cellular characteristics.
has exact synonym: Neoplasm by Morphology
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4741

Chondrogenic Neoplasm
type: Class
subclass of: Mesenchymal Cell Neoplasm
IAO_0000115: A benign, intermediate, or malignant cartilaginous matrix-producing neoplasm. Representative examples include osteochondroma, chondroblastoma, and chondrosarcoma.
has exact synonym: Cartilaginous Neoplasm
has exact synonym: Cartilaginous Tumor
has exact synonym: Chondrogenic Neoplasm
has exact synonym: Chondrogenic Tumor
has exact synonym: Chondromatous Neoplasm
has exact synonym: Chondromatous Tumor
has exact synonym: Neoplasm of Cartilage
has exact synonym: Neoplasm of the Cartilage
has exact synonym: Tumor of Cartilage
has exact synonym: Tumor of the Cartilage
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4755

Malignant Eye Neoplasm
type: Class
subclass of: Eye Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the structures of the eye (conjunctiva, cornea, uvea, retina), the lacrimal gland, and the eyelid. Representative examples include melanoma, carcinoma, lymphoma, and retinoblastoma.
has exact synonym: Cancer of Eye
has exact synonym: Cancer of the Eye
has exact synonym: Eye Cancer
has exact synonym: Eye Neoplasm, Malignant
has exact synonym: Malignant Eye Neoplasm
has exact synonym: Malignant Eye Tumor
has exact synonym: Malignant Neoplasm of Eye
has exact synonym: Malignant Neoplasm of the Eye
has exact synonym: Malignant Ocular Neoplasm
has exact synonym: Malignant Ocular Tumor
has exact synonym: Malignant Tumor of Eye
has exact synonym: Malignant Tumor of the Eye
has exact synonym: Malignant eye cancer, NOS
has exact synonym: eye cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4767

Benign Brain Neoplasm
type: Class
subclass of: Brain Neoplasm
subclass of: Benign Intracranial Neoplasm
IAO_0000115: A primary, slow growing, noninvasive neoplasm of the brain. In children, astrocytomas of the cerebellum represent relatively common benign brain neoplasms. In adults meningiomas, neurilemomas and pituitary tumors comprise the majority of benign tumors.
has exact synonym: Benign Brain Neoplasm
has exact synonym: Benign Brain Tumor
has exact synonym: Benign Neoplasm of Brain
has exact synonym: Benign Neoplasm of the Brain
has exact synonym: Benign Tumor of Brain
has exact synonym: Benign Tumor of the Brain
has exact synonym: Benign neoplasm of brain
has exact synonym: Brain Neoplasms, Benign
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4781

Cardiovascular Neoplasm
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant neoplasm that affects the heart and/or vessels. Representative examples of benign neoplasms include atrial myxoma, hemangioma, and lymphangioma. Representative examples of malignant neoplasms include pericardial malignant mesothelioma and angiosarcoma.
has exact synonym: Cardiovascular Neoplasm
has exact synonym: Cardiovascular Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4784

Malignant Nervous System Neoplasm
type: Class
subclass of: Nervous System Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the nervous system.
has exact synonym: Malignant Neoplasm of Nervous System
has exact synonym: Malignant Neoplasm of the Nervous System
has exact synonym: Malignant Nervous System Neoplasm
has exact synonym: Malignant Nervous System Tumor
has exact synonym: Malignant Tumor of Nervous System
has exact synonym: Malignant Tumor of the Nervous System
has exact synonym: Nervous System Neoplasms, Malignant
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4788

Retinal Neoplasm
type: Class
subclass of: Eye Neoplasm
IAO_0000115: A benign or malignant neoplasm affecting the retina. Representative examples of benign neoplasms include retinocytoma and hemangioma. Representative examples of malignant neoplasms include retinoblastoma, lymphoma and melanoma.
has exact synonym: Neoplasm of Retina
has exact synonym: Neoplasm of the Retina
has exact synonym: Retina Neoplasm
has exact synonym: Retina Tumor
has exact synonym: Retinal Neoplasm
has exact synonym: Retinal Tumor
has exact synonym: Tumor of Retina
has exact synonym: Tumor of the Retina
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4800

Thyroid Gland Carcinoma
type: Class
subclass of: Neck Carcinoma
subclass of: Malignant Thyroid Gland Neoplasm
IAO_0000115: A carcinoma arising from the thyroid gland. It is usually an adenocarcinoma and includes the following main subtypes: follicular, papillary, medullary, poorly differentiated, and anaplastic.
has exact synonym: Cancer of Thyroid
has exact synonym: Cancer of the Thyroid
has exact synonym: Carcinoma of Thyroid
has exact synonym: Carcinoma of Thyroid Gland
has exact synonym: Carcinoma of the Thyroid
has exact synonym: Carcinoma of the Thyroid Gland
has exact synonym: Head and Neck Cancer, Thyroid
has exact synonym: Thyroid Cancer
has exact synonym: Thyroid Carcinoma
has exact synonym: Thyroid Gland Cancer
has exact synonym: Thyroid Gland Carcinoma
has exact synonym: Thyroid cancer
has exact synonym: Thyroid cancer, NOS
has exact synonym: thyroid cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4815

Malignant Glioma
type: Class
subclass of: Glioma
subclass of: Malignant Central Nervous System Neoplasm
IAO_0000115: A malignant tumor of neuroglial tissue. This term may be used to describe one of a number of primary neoplasms of the brain and spinal cord, including astrocytomas, ependymomas, neurocytomas, etc. Malignant gliomas are the most common primary tumors of the brain.
has exact synonym: GLIOMA, MALIGNANT
has exact synonym: Malignant Glial Neoplasm
has exact synonym: Malignant Glial Tumor
has exact synonym: Malignant Glioma
has exact synonym: Malignant Neuroglial Neoplasm
has exact synonym: Malignant Neuroglial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4822

Adrenal Medulla Neoplasm
type: Class
subclass of: Adrenal Gland Neoplasm
IAO_0000115: A benign or malignant (primary or metastatic) neoplasm affecting the adrenal medulla. (NCI05)
has exact synonym: Adrenal Medulla Neoplasm
has exact synonym: Adrenal Medulla Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4856

Malignant Soft Tissue Neoplasm
type: Class
subclass of: Soft Tissue Neoplasm
IAO_0000115: A malignant neoplasm arising exclusively from the soft tissues.
has exact synonym: Malignant Neoplasm of Soft Tissue
has exact synonym: Malignant Neoplasm of the Soft Tissue
has exact synonym: Malignant Soft Tissue Neoplasm
has exact synonym: Malignant Soft Tissue Tumor
has exact synonym: Malignant Tumor of Soft Tissue
has exact synonym: Malignant Tumor of the Soft Tissue
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4867

Lung Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Malignant Lung Neoplasm
IAO_0000115: A carcinoma originating in the lung. Lung carcinomas usually arise from the epithelium that lines the bronchial tree (bronchogenic carcinomas), and are classified as small cell or non-small cell carcinomas. Non-small cell lung carcinomas are usually adenocarcinomas, squamous cell carcinomas, or large cell carcinomas. Metastatic carcinomas to the lung are also common, and can be difficult to distinguish from primary tumors.
has exact synonym: Cancer of Lung
has exact synonym: Cancer of the Lung
has exact synonym: Carcinoma of Lung
has exact synonym: Carcinoma of the Lung
has exact synonym: Lung Cancer
has exact synonym: Lung Carcinoma
has exact synonym: Lung cancer, NOS
has exact synonym: lung cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4878

Benign Bone Neoplasm
type: Class
subclass of: Benign Connective and Soft Tissue Neoplasm
subclass of: Bone Neoplasm
IAO_0000115: A neoplasm that arises from the bone or articular cartilage and does not invade adjacent tissues or metastasize to other anatomic sites.
has exact synonym: Benign Bone Neoplasm
has exact synonym: Benign Bone Tumor
has exact synonym: Benign Neoplasm of Bone
has exact synonym: Benign Neoplasm of the Bone
has exact synonym: Benign Osseous Neoplasm
has exact synonym: Benign Osseous Tumor
has exact synonym: Benign Tumor of Bone
has exact synonym: Benign Tumor of the Bone
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4880

Benign Muscle Neoplasm
type: Class
subclass of: Myomatous Neoplasm
subclass of: Benign Soft Tissue Neoplasm
IAO_0000115: A benign mesenchymal neoplasm arising from smooth, skeletal, or cardiac muscle tissue.
has exact synonym: Benign Muscle Neoplasm
has exact synonym: Benign Muscle Tumor
has exact synonym: Benign Neoplasm of Muscle
has exact synonym: Benign Neoplasm of the Muscle
has exact synonym: Benign Tumor of Muscle
has exact synonym: Benign Tumor of the Muscle
has exact synonym: Myoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4882

Malignant Muscle Neoplasm
type: Class
subclass of: Myomatous Neoplasm
IAO_0000115: A malignant neoplasm affecting the skeletal or smooth muscles. Malignant neoplasms arising from the skeletal muscles are called rhabdomyosarcomas. Malignant neoplasms arising from the smooth muscles are called leiomyosarcomas.
has exact synonym: Malignant Muscle Neoplasm
has exact synonym: Malignant Muscle Tumor
has exact synonym: Malignant Neoplasm of Muscle
has exact synonym: Malignant Neoplasm of the Muscle
has exact synonym: Malignant Tumor of Muscle
has exact synonym: Malignant Tumor of the Muscle
has exact synonym: Myosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4883

Malignant Digestive System Neoplasm
type: Class
subclass of: Digestive System Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving any part of the digestive system.
has exact synonym: Gastrointestinal System Cancer
has exact synonym: Gastrointestinal cancer, NOS
has exact synonym: Malignant Digestive System Neoplasm
has exact synonym: Malignant Gastrointestinal Neoplasm
has exact synonym: Malignant Gastrointestinal System Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4890

Skin Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Malignant Skin Neoplasm
subclass of: Epithelial Skin Neoplasm
IAO_0000115: A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma.
has exact synonym: Carcinoma of Skin
has exact synonym: Carcinoma of the Skin
has exact synonym: Non-Melanoma Cancer of Skin
has exact synonym: Non-Melanoma Cancer of the Skin
has exact synonym: Non-Melanoma Skin Cancer
has exact synonym: Skin Cancer, Non-Melanoma
has exact synonym: Skin Carcinoma
has exact synonym: nonmelanoma skin cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4914

Malignant Germ Cell Tumor
type: Class
subclass of: Germ Cell Tumor
IAO_0000115: A gonadal or extragonadal malignant neoplasm that arises from germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, and seminoma.
has exact synonym: Germ cell cancer, NOS
has exact synonym: Malignant Germ Cell Neoplasm
has exact synonym: Malignant Germ Cell Tumor
has exact synonym: Malignant Neoplasm of Germ Cell
has exact synonym: Malignant Neoplasm of the Germ Cell
has exact synonym: Malignant Tumor of Germ Cell
has exact synonym: Malignant Tumor of the Germ Cell
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4925

Malignant Neck Neoplasm
type: Class
subclass of: Neck Neoplasm
subclass of: Malignant Head and Neck Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm that affects the anatomic structures of the neck region.
has exact synonym: Cancer of Neck
has exact synonym: Cancer of the Neck
has exact synonym: Malignant Neck Neoplasm
has exact synonym: Malignant Neck Tumor
has exact synonym: Malignant Neoplasm of Neck
has exact synonym: Malignant Neoplasm of the Neck
has exact synonym: Malignant Tumor of Neck
has exact synonym: Malignant Tumor of the Neck
has exact synonym: Neck Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4940

Intracranial Neoplasm
type: Class
subclass of: Central Nervous System Neoplasm
IAO_0000115: A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors that occur in the spaces that surround the brain, and neoplasms of the brain.
has exact synonym: Intracranial Central Nervous System Neoplasm
has exact synonym: Intracranial Central Nervous System Tumor
has exact synonym: Intracranial Neoplasm
has exact synonym: Intracranial Tumor
has exact synonym: intracranial tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4953

Malignant Peripheral Nervous System Neoplasm
type: Class
subclass of: Peripheral Nervous System Neoplasm
subclass of: Malignant Nervous System Neoplasm
IAO_0000115: Malignant growth of cells in the peripheral nervous system (PNS)or Autonomic Nervous System (ANS), without specification as to location
has exact synonym: Malignant Neoplasm of PNS
has exact synonym: Malignant Neoplasm of Peripheral Nerve
has exact synonym: Malignant Neoplasm of Peripheral Nervous System
has exact synonym: Malignant Neoplasm of the PNS
has exact synonym: Malignant Neoplasm of the Peripheral Nerve
has exact synonym: Malignant Neoplasm of the Peripheral Nervous System
has exact synonym: Malignant Neoplasms, Peripheral Nerve
has exact synonym: Malignant PNS Neoplasm
has exact synonym: Malignant PNS Tumor
has exact synonym: Malignant Peripheral Nerve Neoplasm
has exact synonym: Malignant Peripheral Nerve Tumor
has exact synonym: Malignant Peripheral Nervous System Neoplasm
has exact synonym: Malignant Peripheral Nervous System Tumor
has exact synonym: Malignant Tumor of PNS
has exact synonym: Malignant Tumor of Peripheral Nerve
has exact synonym: Malignant Tumor of Peripheral Nervous System
has exact synonym: Malignant Tumor of the PNS
has exact synonym: Malignant Tumor of the Peripheral Nerve
has exact synonym: Malignant Tumor of the Peripheral Nervous System
has exact synonym: Peripheral Nervous System Neoplasms, Malignant
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4961

Malignant Thymus Neoplasm
type: Class
subclass of: Malignant Thoracic Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the thymus. This category includes malignant thymomas, thymic lymphomas, primary thymic carcinomas, and metastatic carcinomas from other anatomic sites.
has exact synonym: Cancer of Thymus
has exact synonym: Cancer of the Thymus
has exact synonym: Malignant Neoplasm of Thymus
has exact synonym: Malignant Neoplasm of the Thymus
has exact synonym: Malignant Thymus Neoplasm
has exact synonym: Malignant Thymus Tumor
has exact synonym: Malignant Tumor of Thymus
has exact synonym: Malignant Tumor of the Thymus
has exact synonym: Thymus Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4962

Malignant Infratentorial Neoplasm
type: Class
subclass of: Infratentorial Neoplasm
subclass of: Malignant Brain Neoplasm
IAO_0000115: Malignant neoplasms which arise or occur within the intracranial cavity below the tentorium cerebelli. This includes neoplasms within the brain and/or surrounding spaces.
has exact synonym: Infratentorial Neoplasms, Malignant
has exact synonym: Malignant Infratentorial Neoplasm
has exact synonym: Malignant Infratentorial Tumor
has exact synonym: Malignant Infratentorial Tumors
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4966

Nerve Sheath Neoplasm
type: Class
subclass of: Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from the perineural cells in the sheaths surrounding the nerves. Representative examples include neurofibroma, schwannoma, and malignant peripheral nerve sheath tumor.
has exact synonym: Neoplasm of Nerve Sheath
has exact synonym: Neoplasm of the Nerve Sheath
has exact synonym: Nerve Sheath Neoplasm
has exact synonym: Nerve Sheath Neoplasms
has exact synonym: Nerve Sheath Tumor
has exact synonym: Nerve Sheath Tumors
has exact synonym: Tumor of Nerve Sheath
has OBO namespace: mouse_pathology.ontology
id: NCIT:C4972

Benign Intracranial Neoplasm
type: Class
subclass of: Intracranial Neoplasm
has exact synonym: Benign Intracranial Neoplasm
has exact synonym: Benign Intracranial Tumor
has exact synonym: Intracranial Neoplasms, Benign
has OBO namespace: mouse_pathology.ontology
id: NCIT:C5111

Autonomic Nervous System Neoplasm
type: Class
subclass of: Peripheral Nervous System Neoplasm
IAO_0000115: Benign and malignant neoplasms which arise from or directly involve the central or peripheral elements of the autonomic nervous system.
has exact synonym: Autonomic Nervous System Neoplasm
has exact synonym: Autonomic Nervous System Neoplasms
has exact synonym: Autonomic Nervous System Tumor
has exact synonym: Neoplasm of Autonomic Nervous System
has exact synonym: Neoplasm of the Autonomic Nervous System
has exact synonym: Tumor of Autonomic Nervous System
has exact synonym: Tumor of the Autonomic Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C5112

Malignant Intracranial Neoplasm
type: Class
subclass of: Malignant Central Nervous System Neoplasm
subclass of: Intracranial Neoplasm
has exact synonym: Intracranial Cancer
has exact synonym: Intracranial Neoplasms, Malignant
has exact synonym: Intracranial Tumors, Malignant
has exact synonym: Malignant Intracranial Neoplasm
has exact synonym: Malignant Intracranial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C5114

Mixed Germ Cell-Sex Cord-Stromal Tumor
type: Class
subclass of: Mixed Neoplasm
subclass of: Reproductive Endocrine Neoplasm
IAO_0000115: A biphasic neoplasm that arises from the ovary or the testis. It is characterized by the presence of neoplastic germ cells and neoplastic sex cord-stromal cells. It includes the gonadoblastoma and mixed germ cell-sex cord stromal tumor, unclassifiable.
has exact synonym: Mixed Germ Cell-Sex Cord Neoplasm
has exact synonym: Mixed Germ Cell-Sex Cord Tumor
has exact synonym: Mixed Germ Cell-Sex Cord-Stromal Neoplasm
has exact synonym: Mixed Germ Cell-Sex Cord-Stromal Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C5241

Benign Connective and Soft Tissue Neoplasm
type: Class
subclass of: Connective and Soft Tissue Neoplasm
IAO_0000115: A non-metastasizing neoplasm that arises from the connective and soft tissue. Representative examples include lipoma, leiomyoma, fibroma, and osteoma.
has exact synonym: Benign Connective and Soft Tissue Neoplasm
has exact synonym: Benign Connective and Soft Tissue Tumor
has exact synonym: Benign Mesenchymal Cell Neoplasm
has exact synonym: Benign Neoplasm of the Soft Tissue and Bone
has exact synonym: Benign Tumor of the Soft Tissue and Bone
has exact synonym: CONNECTIVE AND SOFT TISSUE NEOPLASM, BENIGN
has OBO namespace: mouse_pathology.ontology
id: NCIT:C53684

Colorectal Adenoma
type: Class
subclass of: Colorectal Neoplasm
subclass of: Digestive System Adenoma
IAO_0000115: An adenoma that arises from the colon or rectum. The group of colorectal adenomas includes tubular, villous, and tubulovillous adenomas, traditional serrated adenomas, sessile serrated adenomas/polyps, and familial adenomatous polyposis.
has exact synonym: Adenoma of Large Bowel
has exact synonym: Adenoma of Large Intestine
has exact synonym: Adenoma of the Large Bowel
has exact synonym: Adenoma of the Large Intestine
has exact synonym: Colorectal Adenoma
has exact synonym: Large Bowel Adenoma
has exact synonym: Large Intestine Adenoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C5673

Neck Carcinoma
type: Class
subclass of: Head and Neck Carcinoma
subclass of: Malignant Neck Neoplasm
IAO_0000115: A carcinoma that arises from the anatomic structures of the neck region.
has exact synonym: Carcinoma of Neck
has exact synonym: Carcinoma of the Neck
has exact synonym: Neck Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6077

Astrocytoma
type: Class
subclass of: Astrocytic Tumor
IAO_0000115: A tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma.
has exact synonym: Astrocytoma
has exact synonym: astrocytoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C60781

Childhood Neoplasm
type: Class
subclass of: Neoplasm by Special Category
IAO_0000115: A benign or malignant neoplasm arising during childhood.
has exact synonym: Childhood Neoplasm
has exact synonym: Childhood Tumor
has exact synonym: Pediatric Neoplasm
has exact synonym: Pediatric Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6283

Thymus Epithelial Neoplasm
type: Class
subclass of: Epithelial Neoplasm
IAO_0000115: An epithelial neoplasm that affects the thymus gland. This category includes thymomas and carcinomas.
has exact synonym: Epithelial Neoplasm of Thymus
has exact synonym: Epithelial Neoplasm of the Thymus
has exact synonym: Epithelial Tumor of Thymus
has exact synonym: Epithelial Tumor of the Thymus
has exact synonym: Thymic Epithelial Tumor
has exact synonym: Thymic Epithelium Neoplasm
has exact synonym: Thymus Epithelial Neoplasm
has exact synonym: Thymus Epithelial Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6450

Thymic Lymphoma
type: Class
subclass of: Malignant Thymus Neoplasm
subclass of: Mediastinal Lymphoma
IAO_0000115: A lymphoma that arises from the thymus. Representative examples include mediastinal (thymic) large B-cell lymphoma and Hodgkin lymphoma.
has exact synonym: Lymphoma of Thymus
has exact synonym: Lymphoma of the Thymus
has exact synonym: Primary Thymic Lymphoma
has exact synonym: Thymic Lymphoma
has exact synonym: Thymus Lymphoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6451

Benign Smooth Muscle Neoplasm
type: Class
subclass of: Smooth Muscle Neoplasm
subclass of: Benign Muscle Neoplasm
IAO_0000115: A benign mesenchymal neoplasm arising from smooth muscle tissue.
has exact synonym: Benign Neoplasm of Smooth Muscle
has exact synonym: Benign Neoplasm of the Smooth Muscle
has exact synonym: Benign Smooth Muscle Neoplasm
has exact synonym: Benign Smooth Muscle Tumor
has exact synonym: Benign Tumor of Smooth Muscle
has exact synonym: Benign Tumor of the Smooth Muscle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6510

Malignant Smooth Muscle Neoplasm
type: Class
subclass of: Smooth Muscle Neoplasm
subclass of: Malignant Muscle Neoplasm
IAO_0000115: A malignant neoplasm arising from smooth muscle.
has exact synonym: Cancer of Smooth Muscle
has exact synonym: Cancer of the Smooth Muscle
has exact synonym: Malignant Neoplasm of Smooth Muscle
has exact synonym: Malignant Neoplasm of the Smooth Muscle
has exact synonym: Malignant Smooth Muscle Neoplasm
has exact synonym: Malignant Smooth Muscle Tumor
has exact synonym: Malignant Tumor of Smooth Muscle
has exact synonym: Malignant Tumor of the Smooth Muscle
has exact synonym: Smooth Muscle Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6511

Skeletal Muscle Neoplasm
type: Class
subclass of: Myomatous Neoplasm
IAO_0000115: A benign or malignant mesenchymal neoplasm arising from skeletal muscle.
has exact synonym: Neoplasm of Skeletal Muscle
has exact synonym: Neoplasm of the Skeletal Muscle
has exact synonym: Skeletal Muscle Neoplasm
has exact synonym: Skeletal Muscle Tumor
has exact synonym: Tumor of Skeletal Muscle
has exact synonym: Tumor of the Skeletal Muscle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6514

Non-Small Cell Carcinoma
type: Class
subclass of: Carcinoma
IAO_0000115: A malignant epithelial neoplasm characterized by the absence of neoplastic small epithelial cells. A representative example is the lung non-small cell carcinoma.
has exact synonym: Non-Small Cell Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C65151

Malignant Skeletal Muscle Neoplasm
type: Class
subclass of: Malignant Muscle Neoplasm
subclass of: Skeletal Muscle Neoplasm
IAO_0000115: A malignant neoplasm arising from skeletal muscle.
has exact synonym: Malignant Neoplasm of Skeletal Muscle
has exact synonym: Malignant Neoplasm of the Skeletal Muscle
has exact synonym: Malignant Skeletal Muscle Neoplasm
has exact synonym: Malignant Skeletal Muscle Tumor
has exact synonym: Malignant Tumor of Skeletal Muscle
has exact synonym: Malignant Tumor of the Skeletal Muscle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6516

Benign Lymphatic Vessel Neoplasm
type: Class
subclass of: Lymphatic Vessel Neoplasm
subclass of: Benign Vascular Neoplasm
IAO_0000115: A benign neoplasm arising from the lymphatic vessels.
has exact synonym: Benign Lymph Vessel Neoplasm
has exact synonym: Benign Lymph Vessel Tumor
has exact synonym: Benign Lymphatic Vessel Neoplasm
has exact synonym: Benign Lymphatic Vessel Tumor
has exact synonym: Benign Neoplasm of Lymph Vessel
has exact synonym: Benign Neoplasm of Lymphatic Vessel
has exact synonym: Benign Neoplasm of the Lymph Vessel
has exact synonym: Benign Neoplasm of the Lymphatic Vessel
has exact synonym: Benign Tumor of Lymph Vessel
has exact synonym: Benign Tumor of Lymphatic Vessel
has exact synonym: Benign Tumor of the Lymph Vessel
has exact synonym: Benign Tumor of the Lymphatic Vessel
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6524

Myxoma
type: Class
subclass of: Benign Soft Tissue Tumor of Uncertain Differentiation
IAO_0000115: A benign soft tissue neoplasm characterized by the presence of spindle and stellate cells, lobulated growth pattern, and myxoid stroma formation.
has exact synonym: MYXOMA, BENIGN
has exact synonym: Myxoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6577

Benign Soft Tissue Tumor of Uncertain Differentiation
type: Class
subclass of: Benign Soft Tissue Neoplasm
subclass of: Soft Tissue Tumor of Uncertain Differentiation
IAO_0000115: A benign soft tissue tumor in which the line of differentiation is uncertain.
has exact synonym: Benign Soft Tissue Neoplasm of Uncertain Differentiation
has exact synonym: Benign Soft Tissue Tumor of Uncertain Differentiation
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6587

Benign Osteogenic Neoplasm
type: Class
subclass of: Benign Connective and Soft Tissue Neoplasm
subclass of: Osteogenic Neoplasm
IAO_0000115: A non-metastasizing bone-forming neoplasm. This category includes osteoma, osteoid osteoma, and osteoblastoma.
has exact synonym: Benign Osseous Neoplasm
has exact synonym: Benign Osseous Tumor
has exact synonym: Benign Osteogenic Neoplasm
has exact synonym: Benign Osteogenic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6602

Osteogenic Neoplasm
type: Class
subclass of: Mesenchymal Cell Neoplasm
IAO_0000115: A benign, intermediate, or malignant bone-forming neoplasm. Representative examples include osteoma, osteoblastoma, and osteosarcoma.
has exact synonym: Osseous Neoplasm
has exact synonym: Osseous Tumor
has exact synonym: Osteogenic Neoplasm
has exact synonym: Osteogenic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6603

Soft Tissue Fibrosarcoma
type: Class
subclass of: Fibrosarcoma
subclass of: Soft Tissue Sarcoma
IAO_0000115: A usually aggressive malignant neoplasm arising from the soft tissue. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern.
has exact synonym: Fibrosarcoma of Soft Tissue
has exact synonym: Fibrosarcoma of the Soft Tissue
has exact synonym: Soft Tissue Fibrosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6605

Mediastinal Lymphoma
type: Class
subclass of: Malignant Mediastinal Neoplasm
subclass of: Lymphoma by Site
IAO_0000115: A lymphoma that arises from the mediastinum. Representative examples include mediastinal (thymic) large B-cell lymphoma and Hodgkin lymphoma.
has exact synonym: Lymphoma of Mediastinum
has exact synonym: Lymphoma of the Mediastinum
has exact synonym: Mediastinal Lymphoma
has exact synonym: Mediastinal Malignant Lymphoma
has exact synonym: Primary Mediastinal Lymphoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6633

Ependymal Tumor
type: Class
subclass of: Glioma
subclass of: Central Nervous System Neoplasm
IAO_0000115: A group of neoplasms which arise from the ependymal lining of the cerebral ventricles and from the remnants of the central canal of the spinal cord. Ependymal tumors occur predominantly in children and young adults with varied morphological features and biological behavior. There are 4 types: ependymoma, anaplastic ependymoma, myxopapillary ependymoma and subependymoma. (WHO)
has exact synonym: Ependymal Neoplasm
has exact synonym: Ependymal Tumor
has exact synonym: ependymal tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6770

Transitional Cell Neoplasm
type: Class
subclass of: Epithelial Neoplasm
has exact synonym: Transitional Cell Neoplasm
has exact synonym: Transitional Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6783

Cystic Neoplasm
type: Class
subclass of: Neoplasm by Special Category
IAO_0000115: A benign or malignant neoplasm that contains a single or multiple cystic spaces. Examples include cystadenoma, mucinous cystadenocarcinoma, and serous cystadenocarcinoma.
has exact synonym: Cystic Neoplasm
has exact synonym: Cystic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6784

Mixed Neoplasm
type: Class
subclass of: Neoplasm by Morphology
IAO_0000115: A neoplasm composed of at least two distinct cellular populations.
has exact synonym: Mixed Neoplasm
has exact synonym: Mixed Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6930

Astrocytic Tumor
type: Class
subclass of: Glioma
subclass of: Central Nervous System Neoplasm
IAO_0000115: A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma.
has exact synonym: Astrocytic Neoplasm
has exact synonym: Astrocytic Tumor
has exact synonym: Astroglioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6958

Oligodendroglial Tumor
type: Class
subclass of: Glioma
subclass of: Central Nervous System Neoplasm
IAO_0000115: A neoplasm of the central nervous system composed predominantly of cells morphologically resembling oligodendroglia. Oligodendroglial tumors histologically comprise a continuous spectrum ranging from well-differentiated neoplasms to frankly malignant tumors. WHO grading system recognizes two malignancy grades: WHO grade II for well-differentiated tumors (oligodendroglioma) and WHO grade III for anaplastic oligodendroglioma. (Adapted from WHO)
has exact synonym: Oligodendroglial Neoplasm
has exact synonym: Oligodendroglial Tumor
has exact synonym: oligodendroglial tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6960

Neuroblastic Tumor
type: Class
subclass of: Primitive Neuroectodermal Tumor
IAO_0000115: A group of nervous system tumors which display neuronal differentiation. It includes tumors that are composed of immature round cells and tumors that display advanced differentiation and the formation of ganglion cells.
has exact synonym: Neuroblastic Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6963

Meningothelial Cell Neoplasm
type: Class
subclass of: Neoplasm by Morphology
IAO_0000115: A neoplasm that arises from meningothelial cells. This category refers to meningiomas.
has exact synonym: Meningothelial Cell Neoplasm
has exact synonym: Meningothelial Cell Tumor
has exact synonym: Primary Meningeal Neoplasm
has exact synonym: Primary Meningeal Tumor
has exact synonym: Tumor of Meningothelial Cells
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6971

Neoplasm of Uncertain Histogenesis
type: Class
subclass of: Neoplasm by Morphology
has exact synonym: Neoplasm of Uncertain Histogenesis
has exact synonym: Neoplasm of Uncertain Origin
has exact synonym: Tumor of Uncertain Histogenesis
has exact synonym: Tumor of Uncertain Origin
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6974

Central Nervous System Embryonal Neoplasm
type: Class
subclass of: Embryonal Neoplasm
subclass of: Malignant Central Nervous System Neoplasm
IAO_0000115: A malignant neoplasm of embryonal origin, arising from the central nervous system. It usually affects children. Representative examples include ependymoblastoma, medulloblastoma, and atypical teratoid/rhabdoid tumor.
has exact synonym: CNS Embryonal Neoplasm
has exact synonym: CNS Embryonal Tumor
has exact synonym: Central Nervous System Embryonal Neoplasm
has exact synonym: Central Nervous System Embryonal Tumor
has exact synonym: Embryonal Neoplasm of CNS
has exact synonym: Embryonal Neoplasm of Central Nervous System
has exact synonym: Embryonal Neoplasm of the CNS
has exact synonym: Embryonal Neoplasm of the Central Nervous System
has exact synonym: Embryonal Tumor of CNS
has exact synonym: Embryonal Tumor of Central Nervous System
has exact synonym: Embryonal Tumor of the CNS
has exact synonym: Embryonal Tumor of the Central Nervous System
has OBO namespace: mouse_pathology.ontology
id: NCIT:C6990

Melanocytic Neoplasm
type: Class
subclass of: Neoplasm by Morphology
has exact synonym: Melanocytic Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7058

Mesenchymal Cell Neoplasm
type: Class
subclass of: Connective and Soft Tissue Neoplasm
subclass of: Neoplasm by Morphology
IAO_0000115: A benign, intermediate, or malignant neoplasm that arises from the mesenchyma-derived cells of the soft tissue or bone. Representative examples include lipoma, leiomyoma, leiomyosarcoma and osteosarcoma.
has exact synonym: Mesenchymal Cell Neoplasm
has exact synonym: Mesenchymal Cell Tumor
has exact synonym: Mesenchymal Neoplasm
has exact synonym: Mesenchymal Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7059

Retinal Cell Neoplasm
type: Class
subclass of: Neoplasm by Morphology
subclass of: Retinal Neoplasm
has exact synonym: Retinal Cell Neoplasm
has exact synonym: Retinal Cell Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7061

Neoplasm by Special Category
type: Class
subclass of: Neoplasm
IAO_0000115: A neoplasm defined by its unique characteristic as they apply to clinical presentation and course, morphologic patterns, frequency, and/or age distribution.
has exact synonym: Neoplasm by Special Category
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7062

Notochordal Tumor
type: Class
subclass of: Embryonal Neoplasm
subclass of: Bone Neoplasm
IAO_0000115: A bone tumor arising from the remnants of the fetal notochord. This category includes the chordoma and benign notochordal cell tumor.
has exact synonym: Notochordal Neoplasm
has exact synonym: Notochordal Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7063

Lymphocytic Neoplasm
type: Class
subclass of: Hematopoietic and Lymphoid Cell Neoplasm
IAO_0000115: A neoplasm composed of a lymphocytic cell population which is usually malignant (clonal) by molecular genetic and/or immunophenotypic analysis. Lymphocytic neoplasms include Hodgkin and non-Hodgkin lymphomas, acute and chronic lymphocytic leukemias, and plasma cell neoplasms.
has exact synonym: Lymphocytic Neoplasm
has exact synonym: Lymphocytic Tumor
has exact synonym: Lymphocytic and Plasma Cell Neoplasm
has exact synonym: Lymphocytic and Plasma Cell Tumor
has exact synonym: Lymphocytic and Plasma Cell Tumour
has exact synonym: Lymphocytic and Plasmacytic Neoplasm
has exact synonym: Lymphoid Neoplasm
has exact synonym: Lymphoid Tumor
has exact synonym: Lymphoid and Plasma Cell Tumor
has exact synonym: Lymphoid and Plasma Cell Tumour
has exact synonym: Lymphoid and Plasmacytic Neoplasm
has exact synonym: Lymphoid and Plasmacytic Tumor
has exact synonym: Lymphoid and Plasmacytic Tumour
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7065

Neoplastic Polyp
type: Class
subclass of: Neoplasm by Morphology
has exact synonym: Neoplastic Polyp
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7068

Fibroblastic Neoplasm
type: Class
subclass of: Mesenchymal Cell Neoplasm
IAO_0000115: A benign, intermediate, or malignant mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts.
has exact synonym: Fibroblastic Neoplasm
has exact synonym: Fibroblastic Tumor
has exact synonym: Fibrocytic Neoplasm
has exact synonym: Fibrocytic Tumor
has exact synonym: Fibrogenic Neoplasm
has exact synonym: FibrogenicTumor
has exact synonym: Fibrous Neoplasm
has exact synonym: Fibrous Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7075

Common Neoplasm
type: Class
subclass of: Neoplasm by Special Category
has exact synonym: Common Neoplasm
has exact synonym: Common Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7077

Liver and Intrahepatic Bile Duct Neoplasm
type: Class
subclass of: Hepatobiliary Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the liver parenchyma or intrahepatic bile ducts. Representative examples of benign neoplasms include hepatocellular adenoma, and bile duct adenoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and lymphoma.
has exact synonym: Hepatic and Intrahepatic Bile Duct Neoplasm
has exact synonym: Liver and Intrahepatic Bile Duct Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7103

Liver and Intrahepatic Bile Duct Epithelial Neoplasm
type: Class
subclass of: Liver and Intrahepatic Bile Duct Neoplasm
IAO_0000115: A benign or malignant epithelial neoplasm that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of benign epithelial neoplasms include hepatocellular adenoma and intrahepatic bile duct adenoma. Representative examples of malignant epithelial neoplasms include hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
has exact synonym: Epithelial Hepatic and Intrahepatic Bile Duct Neoplasm
has exact synonym: Liver and Intrahepatic Bile Duct Epithelial Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7106

Glandular Cell Neoplasm
type: Class
subclass of: Epithelial Neoplasm
has exact synonym: Glandular Cell Epithelial Neoplasm
has exact synonym: Glandular Cell Epithelium Neoplasm
has exact synonym: Glandular Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7132

Benign Fibroblastic Neoplasm
type: Class
subclass of: Benign Soft Tissue Neoplasm
subclass of: Fibroblastic Neoplasm
IAO_0000115: A benign mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts without malignant characteristics.
has exact synonym: Benign Fibroblastic Neoplasm
has exact synonym: Benign Fibroblastic Tumor
has exact synonym: Benign Fibrocytic Neoplasm
has exact synonym: Benign Fibrocytic Tumor
has exact synonym: Benign Fibrogenic Neoplasm
has exact synonym: Benign Fibrogenic Tumor
has exact synonym: Benign Fibrous Neoplasm
has exact synonym: Benign Fibrous Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7147

Soft Tissue Tumor of Uncertain Differentiation
type: Class
subclass of: Soft Tissue Neoplasm
IAO_0000115: A benign,intermediate, or malignant soft tissue tumor in which the line of differentiation is uncertain. Representative examples include neoplasm with perivascular epithelioid cell differentiation, alveolar soft part sarcoma, desmoplastic small round cell tumor, epithelioid sarcoma, extraskeletal myxoid chondrosarcoma, and synovial sarcoma.
has exact synonym: Soft Tissue Neoplasm of Uncertain Differentiation
has exact synonym: Soft Tissue Tumor of Uncertain Differentiation
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7148

Differentiated Thyroid Gland Carcinoma
type: Class
subclass of: Thyroid Gland Adenocarcinoma
IAO_0000115: An adenocarcinoma arising from the thyroid gland showing extensive evidence of follicular cell differentiation. According to the nuclear features of the malignant follicular cells, it is classified either as papillary, or follicular carcinoma.
has exact synonym: Differentiated Thyroid Cancer
has exact synonym: Differentiated Thyroid Carcinoma
has exact synonym: Differentiated Thyroid Gland Carcinoma
has exact synonym: Thyroid Gland Differentiated Carcinoma
has exact synonym: Thyroid Gland Well Differentiated Carcinoma
has exact synonym: Well Differentiated Thyroid Carcinoma
has exact synonym: Well Differentiated Thyroid Gland Carcinoma
has exact synonym: Well-Differentiated Thyroid Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7153

Melanocytic Skin Neoplasm
type: Class
subclass of: Skin Neoplasm
subclass of: Melanocytic Neoplasm
has exact synonym: Cutaneous Melanocytic Neoplasm
has exact synonym: Melanocytic Neoplasm of Skin
has exact synonym: Melanocytic Skin Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7161

Lymphoma by Site
type: Class
subclass of: Lymphoma
has exact synonym: Lymphoma by Site
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7185

Infrequent Neoplasm
type: Class
subclass of: Neoplasm by Special Category
has exact synonym: Infrequent Neoplasm
has exact synonym: Infrequent Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7201

Reproductive Endocrine Neoplasm
type: Class
subclass of: Reproductive System Neoplasm
IAO_0000115: A benign or malignant endocrine neoplasm that arises from the testis or the ovary.
has exact synonym: Reproductive Endocrine Neoplasm
has exact synonym: Reproductive System Endocrine Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7335

Peritoneal and Retroperitoneal Neoplasms
type: Class
subclass of: Neoplasm by Site
IAO_0000115: A benign or malignant, primary or metastatic neoplasm involving the walls and/or cavities of the abdomen, pelvis, and retroperitoneal space.
has exact synonym: Peritoneal and Retroperitoneal Neoplasms
has exact synonym: Peritoneal and Retroperitoneal Tumors
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7337

Benign Epithelial Skin Neoplasm
type: Class
subclass of: Benign Skin Neoplasm
subclass of: Benign Epithelial Neoplasm
subclass of: Epithelial Skin Neoplasm
has exact synonym: Benign Epithelial Skin Neoplasm
has exact synonym: Benign Epithelial Skin Tumor
has exact synonym: Benign Skin Epithelium Neoplasm
has exact synonym: Benign Skin Epithelium Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7341

Epithelial Skin Neoplasm
type: Class
subclass of: Skin Neoplasm
subclass of: Epithelial Neoplasm
has exact synonym: Epithelial Skin Neoplasm
has exact synonym: Epithelial Skin Tumor
has exact synonym: Skin Epithelium Neoplasm
has exact synonym: Skin Epithelium Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7342

Hair Follicle Neoplasm
type: Class
subclass of: Skin Appendage Neoplasm
IAO_0000115: A benign or malignant neoplasm arising from the hair follicle.
has exact synonym: Hair Follicle Neoplasm
has exact synonym: Hair Follicle Tumor
has exact synonym: Hair Matrix Neoplasm
has exact synonym: Hair Matrix Tumor
has exact synonym: Neoplasm of Hair Follicle
has exact synonym: Neoplasm of the Hair Follicle
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7367

Pilomatricoma
type: Class
subclass of: Benign Germinative Follicular Epithelium Neoplasm
IAO_0000115: A benign adnexal neoplasm arising from hair-bearing skin surfaces, usually the head and neck and upper extremities. It usually presents as a solitary, slow-growing nodular mass. Morphologically, it displays differentiation towards the matrix and inner sheath of the normal hair follicle and the hair cortex. Complete surgical excision is usually curative. Occasionally, it may recur.
has exact synonym: Benign Hair Follicle Neoplasm
has exact synonym: Benign Pilomatricoma
has exact synonym: Benign Pilomatrixoma
has exact synonym: Calcifying Epithelioma of Malherbe
has exact synonym: Calcifying Epitherlioma of Malherbe
has exact synonym: PILOMATRIXOMA, BENIGN
has exact synonym: Pilomatricoma
has exact synonym: Pilomatrixoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7368

Malignant Lung Neoplasm
type: Class
subclass of: Lung Neoplasm
subclass of: Malignant Thoracic Neoplasm
subclass of: Malignant Respiratory Tract Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm involving the lung.
has exact synonym: Malignant Lung Neoplasm
has exact synonym: Malignant Lung Tumor
has exact synonym: Malignant Neoplasm of Lung
has exact synonym: Malignant Neoplasm of the Lung
has exact synonym: Malignant Tumor of Lung
has exact synonym: Malignant Tumor of the Lung
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7377

Blood Vessel Neoplasm
type: Class
subclass of: Vascular Neoplasm
IAO_0000115: A benign neoplasm arising from arteries or veins.
has exact synonym: Blood Vessel Neoplasm
has exact synonym: Blood Vessel Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7387

Vascular Neoplasm
type: Class
subclass of: Cardiovascular Neoplasm
IAO_0000115: A benign, intermediate, or malignant neoplasm arising from vascular tissue including arteries, veins, venous sinuses, lymphatic vessels, arterioles and capillaries. It may occur in essentially any body location and is characterized by the presence of vascular channel formation and endothelial cells.
has exact synonym: Neoplasm of Vascular Tissue
has exact synonym: Neoplasms, Vascular
has exact synonym: Tumor of Vascular Tissue
has exact synonym: Tumors, Vascular
has exact synonym: Vascular Neoplasm
has exact synonym: Vascular Neoplasms
has exact synonym: Vascular Tissue Neoplasm
has exact synonym: Vascular Tissue Tumor
has exact synonym: Vascular Tumor
has exact synonym: Vascular Tumors
has exact synonym: Vascular tumor, NOS
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7388

Benign Vascular Neoplasm
type: Class
subclass of: Benign Connective and Soft Tissue Neoplasm
subclass of: Vascular Neoplasm
IAO_0000115: A benign neoplasm arising from vascular tissue usually of the skin. It is characterized by the presence of vascular channel formation and endothelial cells.
has exact synonym: Benign Vascular Neoplasm
has exact synonym: Benign Vascular Tumor
has exact synonym: Vascular Neoplasms, Benign
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7389

Malignant Vascular Neoplasm
type: Class
subclass of: Malignant Cardiovascular Neoplasm
subclass of: Vascular Neoplasm
IAO_0000115: A malignant neoplasm arising from the vascular tissue. It is characterized by vascular channel formation and malignant endothelial cells.
has exact synonym: Cancerous Tumor of Blood Vessel
has exact synonym: Malignant Tumor of Blood Vessel
has exact synonym: Malignant Vascular Neoplasm
has exact synonym: Malignant Vascular Tissue Neoplasm
has exact synonym: Malignant Vascular Tissue Tumor
has exact synonym: Malignant Vascular Tumor
has exact synonym: Vascular Neoplasms, Malignant
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7390

Papilloma
type: Class
subclass of: Benign Epithelial Neoplasm
subclass of: Papillary Epithelial Neoplasm
IAO_0000115: A benign epithelial neoplasm that projects above the surrounding epithelial surface and consists of villous or arborescent outgrowths of fibrovascular stroma.
has exact synonym: PAPILLOMA, BENIGN
has exact synonym: Papilloma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7440

Malignant Thyroid Gland Neoplasm
type: Class
subclass of: Thyroid Gland Neoplasm
subclass of: Malignant Neck Neoplasm
IAO_0000115: A primary or metastatic malignant neoplasm affecting the thyroid gland.
has exact synonym: Malignant Neoplasm of Thyroid
has exact synonym: Malignant Neoplasm of Thyroid Gland
has exact synonym: Malignant Neoplasm of the Thyroid
has exact synonym: Malignant Neoplasm of the Thyroid Gland
has exact synonym: Malignant Thyroid Gland Neoplasm
has exact synonym: Malignant Thyroid Gland Tumor
has exact synonym: Malignant Thyroid Neoplasm
has exact synonym: Malignant Thyroid Tumor
has exact synonym: Malignant Tumor of Thyroid
has exact synonym: Malignant Tumor of Thyroid Gland
has exact synonym: Malignant Tumor of the Thyroid
has exact synonym: Malignant Tumor of the Thyroid Gland
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7510

Kidney and Ureter Neoplasm
type: Class
subclass of: Urinary System Neoplasm
has exact synonym: Kidney and Ureter Neoplasm
has exact synonym: Kidney and Ureter Tumor
has exact synonym: Renal and Ureteral Neoplasm
has exact synonym: Renal and Ureteral Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7514

Retinoblastoma
type: Class
subclass of: Malignant Retinal Neoplasm
subclass of: Retinal Cell Neoplasm
IAO_0000115: A malignant tumor that originates in the nuclear layer of the retina. As the most common primary tumor of the eye in children, retinoblastoma is still relatively uncommon, accounting for only 1% of all malignant tumors in pediatric patients. Approximately 95% of cases are diagnosed before age 5. These tumors may be multifocal, bilateral, congenital, inherited, or acquired. Seventy-five percent of retinoblastomas are unilateral; 60% occur sporadically. A predisposition to retinoblastoma has been associated with 13q14 cytogenetic abnormalities. Patients with the inherited form also appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma.
has exact synonym: RB
has exact synonym: RETINOBLASTOMA, MALIGNANT
has exact synonym: Retinoblastoma
has exact synonym: retinoblastoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7541

Malignant Kidney Neoplasm
type: Class
subclass of: Kidney Neoplasm
subclass of: Malignant Urinary System Neoplasm
IAO_0000115: Primary or metastatic malignant neoplasm involving the kidney.
has exact synonym: Malignant Kidney Neoplasm
has exact synonym: Malignant Kidney Tumor
has exact synonym: Malignant Neoplasm of Kidney
has exact synonym: Malignant Neoplasm of the Kidney
has exact synonym: Malignant Renal Neoplasm
has exact synonym: Malignant Renal Tumor
has exact synonym: Malignant Tumor of Kidney
has exact synonym: Malignant Tumor of the Kidney
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7548

Malignant Basal Cell Neoplasm
type: Class
subclass of: Basal Cell Neoplasm
IAO_0000115: A neoplasm composed of basal cells that metastasizes to other anatomic sites.
has exact synonym: Malignant Basal Cell Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7586

Oral Cavity Neoplasm
type: Class
subclass of: Oral Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the oral cavity.
has exact synonym: Mouth Neoplasm
has exact synonym: Mouth Tumor
has exact synonym: Oral Cavity Neoplasm
has exact synonym: Oral Cavity Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7606

Common Carcinoma
type: Class
subclass of: Common Neoplasm
has exact synonym: Common Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7629

Childhood Malignant Liver Neoplasm
type: Class
subclass of: Childhood Liver and Intrahepatic Bile Duct Neoplasm
subclass of: Primary Malignant Liver Neoplasm
subclass of: Childhood Malignant Neoplasm
subclass of: Infrequent Neoplasm
IAO_0000115: A malignant neoplasm of the liver developed in childhood. Representative examples include hepatoblastoma, undifferentiated (embryonal) sarcoma, and extrarenal rhabdoid tumor.
has exact synonym: Childhood Cancer of Liver
has exact synonym: Childhood Cancer of the Liver
has exact synonym: Childhood Liver Cancer
has exact synonym: Childhood Malignant Liver Neoplasm
has exact synonym: Childhood Malignant Liver Tumor
has exact synonym: Pediatric Cancer of Liver
has exact synonym: Pediatric Cancer of the Liver
has exact synonym: Pediatric Liver Cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7708

Liver and Intrahepatic Bile Duct Carcinoma
type: Class
subclass of: Primary Malignant Liver Neoplasm
subclass of: Liver and Intrahepatic Bile Duct Epithelial Neoplasm
subclass of: Digestive System Carcinoma
IAO_0000115: A carcinoma that arises from the hepatocytes or intrahepatic bile ducts. The main subtypes are hepatocellular carcinoma (hepatoma) and cholangiocarcinoma.
has exact synonym: Cancer of Liver
has exact synonym: Cancer of Liver and Intrahepatic Biliary Tract
has exact synonym: Cancer of the Liver
has exact synonym: Cancer of the Liver and Intrahepatic Biliary Tract
has exact synonym: Hepatic Cancer
has exact synonym: Liver Cancer
has exact synonym: Liver and Intrahepatic Bile Duct Cancer
has exact synonym: Liver and Intrahepatic Bile Duct Carcinoma
has exact synonym: Liver and Intrahepatic Biliary Tract Cancer
has exact synonym: Liver and Intrahepatic Biliary Tract Carcinoma
has exact synonym: Liver and hepatobiliary cancer, NOS
has exact synonym: Liver/hepatobiliary cancer
has exact synonym: Primary Liver Carcinoma
has exact synonym: liver cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C7927

Thyroid Gland Follicular Carcinoma
type: Class
subclass of: Differentiated Thyroid Gland Carcinoma
IAO_0000115: A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. The nuclear features which characterize the thyroid gland papillary carcinoma are absent. Radiation exposure is a risk factor and it comprises approximately 10% to 15% of thyroid cancers. Clinically, it usually presents as a solitary mass in the thyroid gland. It is generally unifocal and thickly encapsulated and shows invasion of the capsule or the vessels. Diagnostic procedures include thyroid ultrasound and fine needle biopsy.
has exact synonym: CARCINOMA, FOLLICULAR CELL, MALIGNANT
has exact synonym: Follicular Adenocarcinoma
has exact synonym: Follicular Cancer of Thyroid
has exact synonym: Follicular Cancer of Thyroid Gland
has exact synonym: Follicular Cancer of the Thyroid
has exact synonym: Follicular Cancer of the Thyroid Gland
has exact synonym: Follicular Carcinoma
has exact synonym: Follicular Carcinoma of Thyroid
has exact synonym: Follicular Carcinoma of Thyroid Gland
has exact synonym: Follicular Carcinoma of the Thyroid
has exact synonym: Follicular Carcinoma of the Thyroid Gland
has exact synonym: Follicular Thyroid Cancer
has exact synonym: Follicular Thyroid Carcinoma
has exact synonym: Follicular Thyroid Gland Carcinoma
has exact synonym: Follicular thyroid carcinoma
has exact synonym: Thyroid Follicular Carcinoma
has exact synonym: Thyroid Gland Follicular Carcinoma
has exact synonym: Well-Differentiated Follicular Adenocarcinoma
has exact synonym: Well-Differentiated Follicular Carcinoma
has exact synonym: Well-differentiated Follicular Adenocarcinoma
has exact synonym: Well-differentiated Follicular Carcinoma
has exact synonym: follicular thyroid cancer
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8054

Benign Choroid Plexus Neoplasm
type: Class
subclass of: Choroid Plexus Neoplasm
subclass of: Benign Brain Neoplasm
has exact synonym: Benign Choroid Plexus Neoplasm
has exact synonym: Benign Choroid Plexus Neoplasms
has exact synonym: Benign Choroid Plexus Tumor
has exact synonym: Benign Choroid Plexus Tumors
has exact synonym: Benign Neoplasm of Choroid Plexus
has exact synonym: Benign Neoplasm of the Choroid Plexus
has exact synonym: Benign Tumor of Choroid Plexus
has exact synonym: Benign Tumor of the Choroid Plexus
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8405

Stage 0 Skin Melanoma
type: Class
subclass of: Cutaneous Melanoma by AJCC v6 Stage
subclass of: Cutaneous Melanoma by AJCC v7 Stage
IAO_0000115: Stage 0 includes: Tis, N0, M0. Tis: Melanoma in situ. N0: No regional lymph node metastases. M0: No detectable evidence of distant metastases. (from AJCC 6th and 7th Eds.)
has exact synonym: Cutaneous Melanoma in situ
has exact synonym: Malignant Cutaneous Melanoma in situ
has exact synonym: Malignant Skin Melanoma in situ
has exact synonym: Melanoma In Situ
has exact synonym: Melanoma in situ
has exact synonym: Melanoma in situ of Skin
has exact synonym: Melanoma in situ of the Skin
has exact synonym: Skin Melanoma in situ
has exact synonym: Stage 0 Cutaneous Melanoma
has exact synonym: Stage 0 Malignant Cutaneous Melanoma
has exact synonym: Stage 0 Malignant Melanoma
has exact synonym: Stage 0 Malignant Skin Melanoma
has exact synonym: Stage 0 Melanoma
has exact synonym: Stage 0 Melanoma of Skin
has exact synonym: Stage 0 Melanoma of the Skin
has exact synonym: Stage 0 Skin Melanoma
has exact synonym: Stage 0 Skin Melanoma AJCC v6
has exact synonym: Stage 0 Skin Melanoma AJCC v7
has exact synonym: melanoma in situ
has exact synonym: stage 0 melanoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8423

Papillary Epithelial Neoplasm
type: Class
subclass of: Papillary Neoplasm
subclass of: Epithelial Neoplasm
has exact synonym: Papillary Epithelial Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8429

Benign Blood Vessel Neoplasm
type: Class
subclass of: Blood Vessel Neoplasm
subclass of: Benign Vascular Neoplasm
IAO_0000115: A benign neoplasm arising from arteries or veins.
has exact synonym: Benign Blood Vessel Neoplasm
has exact synonym: Benign Blood Vessel Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8537

Malignant Blood Vessel Neoplasm
type: Class
subclass of: Blood Vessel Neoplasm
subclass of: Malignant Vascular Neoplasm
IAO_0000115: A malignant neoplasm arising from the blood vessels.
has exact synonym: Malignant Blood Vessel Neoplasm
has exact synonym: Malignant Blood Vessel Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8538

Malignant Hepatobiliary Neoplasm
type: Class
subclass of: Malignant Digestive System Neoplasm
subclass of: Hepatobiliary Neoplasm
IAO_0000115: A malignant neoplasm that affects the liver parenchyma, bile ducts, and gallbladder. Representative examples include hepatocellular carcinoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma.
has exact synonym: Malignant Hepato-Biliary Neoplasm
has exact synonym: Malignant Hepatobiliary Neoplasm
has exact synonym: Malignant Liver and Biliary Neoplasm
has exact synonym: Malignant Liver and Biliary System Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8609

Hepatobiliary Neoplasm
type: Class
subclass of: Digestive System Neoplasm
IAO_0000115: A benign or malignant neoplasm that affects the liver parenchyma, bile ducts, and gallbladder. Representative examples of benign neoplasms include hepatocellular adenoma, bile duct adenoma, and gallbladder lipoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma.
has exact synonym: Hepatic and Biliary Neoplasms
has exact synonym: Hepatic and Biliary Tumors
has exact synonym: Hepatic, Biliary, and Gallbladder Neoplasms
has exact synonym: Hepato-Biliary Neoplasm
has exact synonym: Hepato-Biliary Tumor
has exact synonym: Hepatobiliary Neoplasm
has exact synonym: Hepatobiliary Tumor
has exact synonym: Hepatobiliary Tumors
has exact synonym: Liver and Biliary Neoplasm
has exact synonym: Liver and Biliary System Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8614

Lymphangioma
type: Class
subclass of: Benign Lymphatic Vessel Neoplasm
IAO_0000115: A benign lesion composed of dilated lymphatic channels. Painless swelling is the usual clinical manifestation.
has exact synonym: LYMPHANGIOMA, BENIGN
has exact synonym: Lymphangioma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8965

Embryonal Rhabdomyosarcoma
type: Class
subclass of: Rhabdomyosarcoma
subclass of: Sarcoma Differentiation Score 3
IAO_0000115: A poorly circumscribed morphologic variant of rhabdomyosarcoma. It is characterized by the presence of primitive skeletal muscle differentiation in any stage of myogenesis.
has exact synonym: ERMS
has exact synonym: Embryonal Rhabdomyosarcoma
has exact synonym: Embryonal rhabdomyosarcoma
has exact synonym: embryonal rhabdomyosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8971

Oral Neoplasm
type: Class
subclass of: Head and Neck Neoplasm
IAO_0000115: A benign or malignant neoplasm involving the oral cavity and/or the lips.
has exact synonym: Lip and Oral Cavity Neoplasm
has exact synonym: Lip and Oral Cavity Tumor
has exact synonym: Lip and Oral Cavity Tumour
has exact synonym: Oral Neoplasm
has exact synonym: Oral Tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8989

Blastoma
type: Class
subclass of: Embryonal Neoplasm
IAO_0000115: A malignant neoplasm composed of undifferentiated cells.
has exact synonym: Blastoma
has exact synonym: Embryoma
has exact synonym: embryoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C8997

Sarcoma by FNCLCC Grade
type: Class
subclass of: Sarcoma
has exact synonym: FNCLCC Tumor Grade in Sarcoma
has exact synonym: Sarcoma by FNCLCC Grade
has exact synonym: Sarcoma by FNCLCC Tumor Differentiation Score
has exact synonym: Tumor Differentiation Score in Sarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9023

Sarcoma Differentiation Score 3
type: Class
subclass of: Sarcoma by FNCLCC Grade
has exact synonym: FNCLCC Sarcoma Grade 3
has exact synonym: Sarcoma Differentiation Score 3
has exact synonym: Sarcoma FNCLCC Grade 3
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9029

Cutaneous Melanoma by AJCC v6 Stage
type: Class
subclass of: Cutaneous Melanoma
has exact synonym: Cutaneous Melanoma by AJCC v6 Stage
has OBO namespace: mouse_pathology.ontology
id: NCIT:C90514

Sarcoma
type: Class
subclass of: Connective and Soft Tissue Neoplasm
IAO_0000115: A usually aggressive malignant neoplasm of the soft tissue or bone. It arises from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the neoplasm. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.
has exact synonym: Mesenchymal Tumor, Malignant
has exact synonym: SARCOMA, MALIGNANT
has exact synonym: Sarcoma
has exact synonym: Sarcoma of Soft Tissue and Bone
has exact synonym: Sarcoma of the Soft Tissue and Bone
has exact synonym: sarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9118

Cutaneous Melanoma by AJCC v7 Stage
type: Class
subclass of: Cutaneous Melanoma
has exact synonym: Cutaneous Melanoma by AJCC v7 Stage
has OBO namespace: mouse_pathology.ontology
id: NCIT:C91231

Osteosarcoma
type: Class
subclass of: Osteogenic Neoplasm
subclass of: Sarcoma
IAO_0000115: A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs.
has exact synonym: OSTEOSARCOMA, MALIGNANT
has exact synonym: Osteogenic Sarcoma
has exact synonym: Osteosarcoma
has exact synonym: osteogenic sarcoma
has exact synonym: osteosarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9145

Central Nervous System Neoplasm
type: Class
subclass of: Nervous System Neoplasm
IAO_0000115: A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia.
has exact synonym: CNS Neoplasm
has exact synonym: CNS Tumor
has exact synonym: CNS tumor
has exact synonym: Central Nervous System Neoplasm
has exact synonym: Central Nervous System Tumor
has exact synonym: Neoplasm of CNS
has exact synonym: Neoplasm of Central Nervous System
has exact synonym: Neoplasm of the Central Nervous System
has exact synonym: Tumor of CNS
has exact synonym: Tumor of Central Nervous System
has exact synonym: Tumor of the CNS
has exact synonym: Tumor of the Central Nervous System
has exact synonym: central nervous system tumor
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9293

Histiocytic and Dendritic Cell Neoplasm
type: Class
subclass of: Hematopoietic and Lymphoid Cell Neoplasm
subclass of: Infrequent Neoplasm
IAO_0000115: Rare tumors that affect the hematopoietic and lymphoid tissues. The cells of origin are the histiocytes and accessory cells. They can occur at any age and show no significant variations in geographical distribution. This category includes the histiocytic sarcoma, Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitading dendritic cell sarcoma/tumor, follicular dendritic cell sarcoma/tumor, and dendritic cell sarcoma, not otherwise specified. (WHO, 2001)
has exact synonym: Histiocytic and Dendritic Cell Neoplasm
has exact synonym: Histiocytic and Dendritic Cell Neoplasms
has exact synonym: Histiocytic and Dendritic Cell Tumors
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9294

Malignant Urinary System Neoplasm
type: Class
subclass of: Urinary System Neoplasm
IAO_0000115: A primary or metastatic malignant tumor involving the urinary system. Common tumor types include carcinomas, lymphomas, and sarcomas.
has exact synonym: Malignant Urinary System Neoplasm
has exact synonym: Malignant Urinary Tract Neoplasm
has exact synonym: Urothelial tract/bladder cancer, NOS
has exact synonym: Urothelial/bladder cancer, NOS
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9297

Malignant Neoplasm
type: Class
subclass of: Neoplasm by Special Category
IAO_0000115: A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.
has exact synonym: CA
has exact synonym: Cancer
has exact synonym: Malignancy
has exact synonym: Malignant Growth
has exact synonym: Malignant Neoplasm
has exact synonym: Malignant Neoplastic Disease
has exact synonym: Malignant Tumor
has exact synonym: NEOPLASM, MALIGNANT
has exact synonym: cancer
has exact synonym: malignancy
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9305

Soft Tissue Sarcoma
type: Class
subclass of: Malignant Soft Tissue Neoplasm
subclass of: Sarcoma
IAO_0000115: A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.
has exact synonym: Connective Tissue Sarcoma
has exact synonym: Non-Rhabdo. soft tissue sarcoma
has exact synonym: Non-Rhabdomyosarcoma soft tissue sarcoma, NOS
has exact synonym: Sarcoma of Soft Tissue
has exact synonym: Sarcoma of the Soft Tissue
has exact synonym: Soft Tissue Sarcoma
has exact synonym: Soft tissue sarcoma
has exact synonym: soft tissue sarcoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9306

Seminoma
type: Class
subclass of: Germinomatous Germ Cell Tumor
subclass of: Malignant Germ Cell Tumor
IAO_0000115: A radiosensitive malignant germ cell tumor found in the testis (especially undescended), and extragonadal sites (anterior mediastinum and pineal gland). It is characterized by the presence of uniform cells with clear or dense cytoplasm which contains glycogen, and by a large nucleus which contains one or more nucleoli. The neoplastic germ cells form aggregates separated by fibrous septa. The fibrous septa contain chronic inflammatory cells, mainly lymphocytes.
has exact synonym: SEMINOMA, MALIGNANT
has exact synonym: Seminoma
has exact synonym: Seminoma, Pure
has exact synonym: seminoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9309

Bone Neoplasm
type: Class
subclass of: Connective and Soft Tissue Neoplasm
IAO_0000115: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.
has exact synonym: Bone Neoplasm
has exact synonym: Bone Neoplasms
has exact synonym: Bone Tumor
has exact synonym: Bone Tumors
has exact synonym: Neoplasm of Bone
has exact synonym: Neoplasm of the Bone
has exact synonym: Osseous Neoplasm
has exact synonym: Osseous Tumor
has exact synonym: Tumor of Bone
has exact synonym: Tumor of the Bone
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9343

Plasmacytoma
type: Class
subclass of: Plasma Cell Neoplasm
IAO_0000115: A malignant (clonal) proliferation of plasma cells that are cytologically and immunophenotypically identical to those of plasma cell myeloma, but manifest a localized osseous or extraosseous growth pattern. (WHO, 2001)
has exact synonym: Plasmacytoma
has exact synonym: plasmacytoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9349

Sarcoma by NCI Grade
type: Class
subclass of: Sarcoma
has exact synonym: NCI Tumor Grade in Sarcoma
has exact synonym: Sarcoma by NCI Grade
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9387

Sarcoma NCI Grade 3
type: Class
subclass of: Sarcoma by NCI Grade
has exact synonym: Sarcoma NCI Grade 3
has exact synonym: Sarcoma NCI Grade III
has OBO namespace: mouse_pathology.ontology
id: NCIT:C9415

Colorectal Adenomatous Polyp
type: Class
subclass of: Adenomatous Polyp
subclass of: Colorectal Adenoma
IAO_0000115: A polypoid adenoma that arises from and protrudes into the lumen of the colon or rectum. Epithelial dysplasia is always present. According to the architectural pattern it is classified as tubular, tubulovillous, or villous.
has exact synonym: Adenomatous Polyp of Large Bowel
has exact synonym: Adenomatous Polyp of the Large Bowel
has exact synonym: Colorectal Adenomatous Polyp
has exact synonym: Large Bowel Adenomatous Polyp
has OBO namespace: mouse_pathology.ontology
id: NCIT:C96478

Benign Liver and Intrahepatic Bile Duct Epithelial Neoplasm
type: Class
subclass of: Liver and Intrahepatic Bile Duct Epithelial Neoplasm
IAO_0000115: A non-metastasizing neoplasm that arises from the hepatocytes or intrahepatic bile ducts. Representative examples include hepatocellular adenoma and bile duct adenoma.
has exact synonym: Benign Liver and Intrahepatic Bile Duct Epithelial Neoplasm
has OBO namespace: mouse_pathology.ontology
id: NCIT:C96756

Digestive System Carcinoma
type: Class
subclass of: Carcinoma
subclass of: Malignant Digestive System Neoplasm
IAO_0000115: A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma.
has exact synonym: Carcinoma of the Gastrointestinal System
has exact synonym: Digestive System Carcinoma
has exact synonym: Gastrointestinal System Carcinoma
has OBO namespace: mouse_pathology.ontology
id: NCIT:C96963

part of
has OBO namespace: mouse_pathology.ontology
id: part_of