format-version: 1.2
data-version: releases/2019-05-22
ontology: xpo
property_value: http://purl.org/dc/elements/1.1/description "Ontology about Xenopus." xsd:string
property_value: http://purl.org/dc/elements/1.1/title "Xenopus Phenotype Ontology" xsd:string
property_value: http://purl.org/dc/terms/license "CC-BY" xsd:string

[Term]
id: BFO:0000001
name: entity
property_value: BFO:0000179 "entity" xsd:string
property_value: BFO:0000180 "Entity" xsd:string
property_value: IAO:0000112 "Julius Caesar" xsd:string
property_value: IAO:0000112 "the Second World War" xsd:string
property_value: IAO:0000112 "Verdi’s Requiem" xsd:string
property_value: IAO:0000112 "your body mass index" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string
property_value: IAO:0000116 "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", http://www.w3.org/2000/01/rdf-schema#seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"}
property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000002
name: continuant
def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." []
is_a: BFO:0000001 ! entity
disjoint_from: BFO:0000003 ! occurrent
relationship: part_of BFO:0000002 ! continuant
property_value: BFO:0000179 "continuant" xsd:string
property_value: BFO:0000180 "Continuant" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string
property_value: IAO:0000116 "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"}
property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000003
name: occurrent
def: "An entity that has temporal parts and that happens, unfolds or develops through time." []
is_a: BFO:0000001 ! entity
relationship: part_of BFO:0000003 ! occurrent
property_value: BFO:0000179 "occurrent" xsd:string
property_value: BFO:0000180 "Occurrent" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string
property_value: IAO:0000116 "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"}
property_value: IAO:0000116 "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"}
property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"}
property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000004
name: independent continuant
def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." []
def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000020 ! specifically dependent continuant
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: part_of BFO:0000004 ! independent continuant
property_value: BFO:0000179 "ic" xsd:string
property_value: BFO:0000180 "IndependentContinuant" xsd:string
property_value: IAO:0000112 "a chair" xsd:string
property_value: IAO:0000112 "a heart" xsd:string
property_value: IAO:0000112 "a leg" xsd:string
property_value: IAO:0000112 "a molecule" xsd:string
property_value: IAO:0000112 "a spatial region" xsd:string
property_value: IAO:0000112 "an atom" xsd:string
property_value: IAO:0000112 "an orchestra." xsd:string
property_value: IAO:0000112 "an organism" xsd:string
property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string
property_value: IAO:0000112 "the interior of your mouth" xsd:string
property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000015
name: process
def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." []
def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
is_a: BFO:0000003 ! occurrent
property_value: BFO:0000179 "process" xsd:string
property_value: BFO:0000180 "Process" xsd:string
property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string
property_value: IAO:0000112 "a process of meiosis" xsd:string
property_value: IAO:0000112 "a process of sleeping" xsd:string
property_value: IAO:0000112 "the course of a disease" xsd:string
property_value: IAO:0000112 "the flight of a bird" xsd:string
property_value: IAO:0000112 "the life of an organism" xsd:string
property_value: IAO:0000112 "your process of aging." xsd:string
property_value: IAO:0000116 "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string
property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000017
name: realizable entity
def: "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." []
is_a: BFO:0000020 ! specifically dependent continuant
disjoint_from: BFO:0000019 ! quality
relationship: part_of BFO:0000017 ! realizable entity
property_value: BFO:0000179 "realizable" xsd:string
property_value: BFO:0000180 "RealizableEntity" xsd:string
property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string
property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string
property_value: IAO:0000112 "the function of your reproductive organs" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string
property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000019
name: quality
is_a: BFO:0000020 ! specifically dependent continuant
relationship: part_of BFO:0000019 ! quality
property_value: BFO:0000179 "quality" xsd:string
property_value: BFO:0000180 "Quality" xsd:string
property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string
property_value: IAO:0000112 "the color of a tomato" xsd:string
property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string
property_value: IAO:0000112 "the mass of this piece of gold." xsd:string
property_value: IAO:0000112 "the shape of your nose" xsd:string
property_value: IAO:0000112 "the shape of your nostril" xsd:string
property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000020
name: specifically dependent continuant
def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." []
def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: part_of BFO:0000020 ! specifically dependent continuant
property_value: BFO:0000179 "sdc" xsd:string
property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string
property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string
property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string
property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string
property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string
property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string
property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string
property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string
property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the shape of this hole." xsd:string
property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string
property_value: IAO:0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"}
property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000031
name: generically dependent continuant
def: "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time." []
def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
is_a: BFO:0000002 ! continuant
relationship: part_of BFO:0000031 ! generically dependent continuant
property_value: BFO:0000179 "gdc" xsd:string
property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string
property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string
property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string
property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string
property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000040
name: material entity
def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." []
is_a: BFO:0000004 ! independent continuant
property_value: BFO:0000179 "material" xsd:string
property_value: BFO:0000180 "MaterialEntity" xsd:string
property_value: IAO:0000112 "a flame" xsd:string
property_value: IAO:0000112 "a forest fire" xsd:string
property_value: IAO:0000112 "a human being" xsd:string
property_value: IAO:0000112 "a hurricane" xsd:string
property_value: IAO:0000112 "a photon" xsd:string
property_value: IAO:0000112 "a puff of smoke" xsd:string
property_value: IAO:0000112 "a sea wave" xsd:string
property_value: IAO:0000112 "a tornado" xsd:string
property_value: IAO:0000112 "an aggregate of human beings." xsd:string
property_value: IAO:0000112 "an energy wave" xsd:string
property_value: IAO:0000112 "an epidemic" xsd:string
property_value: IAO:0000112 "the undetached arm of a human being" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string
property_value: IAO:0000116 "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string
property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: CARO:0000000
name: anatomical entity
is_a: CARO:0030000 ! biological entity
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl

[Term]
id: CARO:0000003
name: connected anatomical structure
is_a: CARO:0000006 ! material anatomical entity
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl

[Term]
id: CARO:0000006
name: material anatomical entity
is_a: BFO:0000040 ! material entity
is_a: CARO:0000000 ! anatomical entity
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl

[Term]
id: CARO:0000014
name: cell part
is_a: CARO:0000003 ! connected anatomical structure
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl
property_value: IAO:0000589 "cell part (CARO)" xsd:string

[Term]
id: CARO:0010000
name: multicellular anatomical structure
is_a: CARO:0000003 ! connected anatomical structure
relationship: RO:0002207 CARO:0010000 ! directly develops from multicellular anatomical structure
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl

[Term]
id: CARO:0030000
name: biological entity
is_a: BFO:0000004 ! independent continuant

[Term]
id: CHEBI:24431
name: chemical entity
namespace: chebi_ontology
def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." []
subset: 3_STAR
synonym: "chemical entity" EXACT [UniProt]

[Term]
id: CL:0000000
name: cell
is_a: CARO:0000003 ! connected anatomical structure
relationship: RO:0002207 CL:0000000 ! directly develops from cell
property_value: IAO:0000412 http://purl.obolibrary.org/obo/cl.owl

[Term]
id: CL:0000540
name: neuron
is_a: CL:0000000 ! cell
property_value: IAO:0000412 http://purl.obolibrary.org/obo/cl.owl

[Term]
id: GO:0000003
name: reproduction
namespace: biological_process
alt_id: GO:0019952
alt_id: GO:0050876
def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
synonym: "reproductive physiological process" EXACT []
xref: Wikipedia:Reproduction
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0000235
name: astral microtubule
namespace: cellular_component
def: "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [ISBN:0815316194]
is_a: GO:0005876 ! spindle microtubule
is_a: GO:0005881 ! cytoplasmic microtubule
intersection_of: GO:0005876 ! spindle microtubule
intersection_of: part_of GO:0005818 ! aster
relationship: part_of GO:0005818 ! aster

[Term]
id: GO:0000278
name: mitotic cell cycle
namespace: biological_process
alt_id: GO:0007067
def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_yeast
synonym: "mitosis" RELATED []
xref: MIPS_funcat:10.03.01
xref: MIPS_funcat:10.03.01.01
xref: Wikipedia:Mitosis
is_a: GO:0007049 ! cell cycle
intersection_of: GO:0007049 ! cell cycle
intersection_of: has_part GO:0140014 ! mitotic nuclear division
relationship: has_part GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0000280
name: nuclear division
namespace: biological_process
def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah]
subset: goslim_pir
synonym: "karyokinesis" RELATED []
xref: MIPS_funcat:10.03.04
xref: MIPS_funcat:10.03.04.07
is_a: GO:0048285 ! organelle fission

[Term]
id: GO:0000281
name: mitotic cytokinesis
namespace: biological_process
def: "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:mtg_cell_cycle]
subset: goslim_pombe
synonym: "cytokinesis after mitosis" EXACT []
is_a: GO:0061640 ! cytoskeleton-dependent cytokinesis
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0061640 ! cytoskeleton-dependent cytokinesis
intersection_of: part_of GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0000910
name: cytokinesis
namespace: biological_process
alt_id: GO:0007104
alt_id: GO:0016288
alt_id: GO:0033205
def: "The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells." [GOC:mtg_cell_cycle]
comment: Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639.  Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.
subset: gocheck_do_not_manually_annotate
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_yeast
synonym: "cell cycle cytokinesis" EXACT []
synonym: "cytokinesis involved in cell cycle" EXACT [GOC:dph, GOC:tb]
xref: MIPS_funcat:10.03.03
xref: Wikipedia:Cytokinesis
is_a: GO:0022402 ! cell cycle process
relationship: has_part GO:0090148 ! membrane fission
relationship: part_of GO:0051301 ! cell division

[Term]
id: GO:0001508
name: action potential
namespace: biological_process
def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]
comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.
xref: MIPS_funcat:34.03.03
is_a: GO:0042391 ! regulation of membrane potential

[Term]
id: GO:0001667
name: ameboidal-type cell migration
namespace: biological_process
def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph]
comment: Note that this term refers to a mode of migration rather than to any particular cell type.
synonym: "ameboid cell migration" EXACT []
synonym: "amoeboid cell migration" EXACT []
synonym: "amoeboidal cell migration" EXACT []
is_a: GO:0016477 ! cell migration

[Term]
id: GO:0001704
name: formation of primary germ layer
namespace: biological_process
def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
relationship: part_of GO:0007369 ! gastrulation

[Term]
id: GO:0001705
name: ectoderm formation
namespace: biological_process
def: "The formation of ectoderm during gastrulation." [GOC:go_curators]
is_a: GO:0001704 ! formation of primary germ layer
relationship: part_of GO:0007398 ! ectoderm development

[Term]
id: GO:0001706
name: endoderm formation
namespace: biological_process
def: "The formation of the endoderm during gastrulation." [GOC:go_curators]
synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0001704 ! formation of primary germ layer
relationship: part_of GO:0007492 ! endoderm development

[Term]
id: GO:0001707
name: mesoderm formation
namespace: biological_process
def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators]
is_a: GO:0001704 ! formation of primary germ layer
relationship: part_of GO:0048332 ! mesoderm morphogenesis

[Term]
id: GO:0003002
name: regionalization
namespace: biological_process
def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete]
synonym: "pattern formation" RELATED [GOC:dph]
is_a: GO:0007389 ! pattern specification process

[Term]
id: GO:0003006
name: developmental process involved in reproduction
namespace: biological_process
def: "A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete]
synonym: "puberty" NARROW [GOC:dph]
synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb]
is_a: GO:0022414 ! reproductive process
is_a: GO:0032502 ! developmental process
intersection_of: GO:0032502 ! developmental process
intersection_of: part_of GO:0000003 ! reproduction

[Term]
id: GO:0003008
name: system process
namespace: biological_process
def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio]
synonym: "organ system process" EXACT []
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0003401
name: axis elongation
namespace: biological_process
def: "The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "elongation of an axis" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0060560 ! developmental growth involved in morphogenesis
created_by: dph
creation_date: 2009-12-21T01:12:15Z

[Term]
id: GO:0003674
name: molecular_function
namespace: molecular_function
alt_id: GO:0005554
def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt]
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "molecular function" EXACT []
is_a: BFO:0000015 ! process
property_value: IAO:0000589 "molecular process" xsd:string

[Term]
id: GO:0003824
name: catalytic activity
namespace: molecular_function
def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb]
xref: Wikipedia:Enzyme
is_a: GO:0003674 ! molecular_function

[Term]
id: GO:0004871
name: obsolete signal transducer activity
namespace: molecular_function
alt_id: GO:0005062
alt_id: GO:0009369
alt_id: GO:0009370
def: "OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:go_curators]
comment: This term was obsoleted because it was not clearly defined and is not a useful grouping term, see https://github.com/geneontology/go-ontology/issues/14232.
synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity" NARROW []
synonym: "quorum sensing response regulator activity" NARROW []
synonym: "quorum sensing signal generator activity" NARROW []
is_obsolete: true

[Term]
id: GO:0005102
name: signaling receptor binding
namespace: molecular_function
def: "Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:bf, GOC:ceb, ISBN:0198506732]
comment: Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_plant
synonym: "receptor binding" BROAD []
synonym: "receptor ligand" NARROW []
synonym: "receptor-associated protein activity" RELATED []
xref: Wikipedia:Ligand_(biochemistry)
is_a: GO:0005515 ! protein binding

[Term]
id: GO:0005488
name: binding
namespace: molecular_function
def: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732]
comment: Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.
subset: gocheck_do_not_manually_annotate
subset: goslim_pir
subset: goslim_plant
synonym: "ligand" NARROW []
xref: Wikipedia:Binding_(molecular)
is_a: GO:0003674 ! molecular_function

[Term]
id: GO:0005515
name: protein binding
namespace: molecular_function
alt_id: GO:0001948
alt_id: GO:0045308
def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "glycoprotein binding" NARROW []
synonym: "protein amino acid binding" EXACT []
xref: MIPS_funcat:16.01
xref: MIPS_funcat:18.01.07
xref: Reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3"
xref: Reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"
is_a: GO:0005488 ! binding

[Term]
id: GO:0005575
name: cellular_component
namespace: cellular_component
alt_id: GO:0008372
def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome)." [GOC:pdt, NIF_Subcellular:sao-1337158144]
comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "cell or subcellular entity" EXACT []
synonym: "cellular component" EXACT []
synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315]
xref: NIF_Subcellular:sao-1337158144
xref: NIF_Subcellular:sao1337158144

[Term]
id: GO:0005622
name: intracellular
namespace: cellular_component
def: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732]
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
synonym: "internal to cell" EXACT []
synonym: "nucleocytoplasm" RELATED [GOC:mah]
synonym: "protoplasm" EXACT []
synonym: "protoplast" RELATED [GOC:mah]
xref: Wikipedia:Intracellular
is_a: GO:0044464 ! cell part

[Term]
id: GO:0005623
name: cell
namespace: cellular_component
def: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
xref: NIF_Subcellular:sao1813327414
xref: Wikipedia:Cell_(biology)
is_a: GO:0005575 ! cellular_component
property_value: IAO:0000589 "cell and encapsulating structures" xsd:string

[Term]
id: GO:0005634
name: nucleus
namespace: cellular_component
def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "cell nucleus" EXACT []
synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757]
xref: MIPS_funcat:70.10
xref: NIF_Subcellular:sao1702920020
xref: Wikipedia:Cell_nucleus
is_a: GO:0043231 ! intracellular membrane-bounded organelle
property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl

[Term]
id: GO:0005737
name: cytoplasm
namespace: cellular_component
def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
xref: MIPS_funcat:70.03
xref: Wikipedia:Cytoplasm
is_a: GO:0044424 ! intracellular part

[Term]
id: GO:0005773
name: vacuole
namespace: cellular_component
def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "vacuolar carboxypeptidase Y" RELATED []
xref: MIPS_funcat:70.25
xref: Wikipedia:Vacuole
is_a: GO:0043231 ! intracellular membrane-bounded organelle
is_a: GO:0044444 ! cytoplasmic part

[Term]
id: GO:0005818
name: aster
namespace: cellular_component
def: "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." [GOC:clt]
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
is_a: GO:0044430 ! cytoskeletal part
is_a: GO:0099080 ! supramolecular complex
relationship: part_of GO:0005819 ! spindle

[Term]
id: GO:0005819
name: spindle
namespace: cellular_component
def: "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." [ISBN:0198547684]
xref: Wikipedia:Spindle_apparatus
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
is_a: GO:0044430 ! cytoskeletal part
relationship: part_of GO:0015630 ! microtubule cytoskeleton

[Term]
id: GO:0005856
name: cytoskeleton
namespace: cellular_component
def: "Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, ISBN:0198547684, PMID:16959967]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
xref: MIPS_funcat:70.04
xref: Wikipedia:Cytoskeleton
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle

[Term]
id: GO:0005874
name: microtubule
namespace: cellular_component
def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568]
subset: goslim_metagenomics
synonym: "microtubuli" EXACT []
synonym: "microtubulus" EXACT []
synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196]
xref: NIF_Subcellular:sao1846835077
xref: Wikipedia:Microtubule
is_a: GO:0099513 ! polymeric cytoskeletal fiber
relationship: part_of GO:0015630 ! microtubule cytoskeleton

[Term]
id: GO:0005876
name: spindle microtubule
namespace: cellular_component
def: "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." [ISBN:0815316194]
is_a: GO:0005874 ! microtubule
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005819 ! spindle
relationship: part_of GO:0005819 ! spindle

[Term]
id: GO:0005880
name: nuclear microtubule
namespace: cellular_component
def: "Any microtubule in the nucleus of a cell." [GOC:mah]
is_a: GO:0005874 ! microtubule
is_a: GO:0044428 ! nuclear part
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005634 ! nucleus

[Term]
id: GO:0005881
name: cytoplasmic microtubule
namespace: cellular_component
def: "Any microtubule in the cytoplasm of a cell." [GOC:mah]
synonym: "non-spindle-associated astral microtubule" NARROW []
is_a: GO:0005874 ! microtubule
is_a: GO:0044444 ! cytoplasmic part
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0005884
name: actin filament
namespace: cellular_component
def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339]
synonym: "microfilament" EXACT []
xref: FMA:63850
xref: NIF_Subcellular:sao1588493326
xref: Wikipedia:Actin
is_a: GO:0099513 ! polymeric cytoskeletal fiber
relationship: part_of GO:0015629 ! actin cytoskeleton

[Term]
id: GO:0005886
name: plasma membrane
namespace: cellular_component
alt_id: GO:0005904
def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_plant
subset: goslim_yeast
synonym: "bacterial inner membrane" NARROW []
synonym: "cell membrane" EXACT []
synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645]
synonym: "cytoplasmic membrane" EXACT []
synonym: "inner endospore membrane" NARROW []
synonym: "juxtamembrane" BROAD []
synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah]
synonym: "plasmalemma" EXACT []
xref: NIF_Subcellular:sao1663586795
xref: Wikipedia:Cell_membrane
is_a: GO:0016020 ! membrane
is_a: GO:0044464 ! cell part
relationship: part_of GO:0071944 ! cell periphery

[Term]
id: GO:0006793
name: phosphorus metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai]
subset: goslim_pir
synonym: "phosphorus metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process

[Term]
id: GO:0006796
name: phosphate-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai]
synonym: "phosphate metabolic process" RELATED []
synonym: "phosphate metabolism" EXACT []
xref: MIPS_funcat:01.04
is_a: GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0006928
name: movement of cell or subcellular component
namespace: biological_process
def: "The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore." [GOC:dgh, GOC:dph, GOC:jl, GOC:mlg]
comment: Note that in GO cellular components include whole cells (cell is_a cellular component).
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "cell movement" RELATED []
synonym: "cellular component motion" EXACT [GOC:dph, GOC:jl]
synonym: "cellular component movement" EXACT []
xref: MIPS_funcat:02.45.11
xref: MIPS_funcat:34.05
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0006950
name: response to stress
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
synonym: "response to abiotic stress" RELATED []
synonym: "response to biotic stress" RELATED []
xref: MIPS_funcat:32.01
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0006996
name: organelle organization
namespace: biological_process
alt_id: GO:1902589
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_pir
synonym: "organelle organisation" EXACT [GOC:curators]
synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah]
synonym: "single organism organelle organization" EXACT [GOC:TermGenie]
synonym: "single-organism organelle organization" RELATED []
is_a: GO:0016043 ! cellular component organization
created_by: jl
creation_date: 2013-12-19T15:25:51Z

[Term]
id: GO:0007010
name: cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_yeast
synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah]
synonym: "cytoskeletal regulator activity" RELATED []
synonym: "cytoskeleton organisation" EXACT [GOC:curators]
synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah]
xref: MIPS_funcat:42.04
is_a: GO:0006996 ! organelle organization

[Term]
id: GO:0007049
name: cell cycle
namespace: biological_process
def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle]
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
synonym: "cell-division cycle" EXACT []
xref: MIPS_funcat:10
xref: MIPS_funcat:10.03
xref: Wikipedia:Cell_cycle
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0007088
name: regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators]
synonym: "regulation of mitosis" EXACT []
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0140014 ! mitotic nuclear division
relationship: regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0007154
name: cell communication
namespace: biological_process
def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah]
subset: goslim_pir
subset: goslim_plant
xref: Wikipedia:Cell_signaling
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0007165
name: signal transduction
namespace: biological_process
alt_id: GO:0023033
def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11]
comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
synonym: "signaling cascade" NARROW []
synonym: "signaling pathway" RELATED []
synonym: "signalling cascade" NARROW []
synonym: "signalling pathway" RELATED [GOC:mah]
xref: MIPS_funcat:30
xref: Wikipedia:Signal_transduction
is_a: GO:0009987 ! cellular process
is_a: GO:0050794 ! regulation of cellular process
relationship: part_of GO:0007154 ! cell communication
relationship: part_of GO:0023052 ! signaling
relationship: part_of GO:0051716 ! cellular response to stimulus

[Term]
id: GO:0007267
name: cell-cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell.  Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
synonym: "cell-cell signalling" EXACT []
is_a: GO:0007154 ! cell communication
is_a: GO:0023052 ! signaling

[Term]
id: GO:0007268
name: chemical synaptic transmission
namespace: biological_process
def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435]
subset: goslim_synapse
synonym: "neurotransmission" RELATED [GOC:dph]
synonym: "signal transmission across a synapse" BROAD []
synonym: "synaptic transmission" BROAD []
xref: MIPS_funcat:34.03.01
xref: Wikipedia:Neurotransmission
is_a: GO:0098916 ! anterograde trans-synaptic signaling

[Term]
id: GO:0007275
name: multicellular organism development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb]
comment: Note that this term was 'developmental process'.
subset: goslim_chembl
subset: goslim_plant
xref: MIPS_funcat:41
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0048856 ! anatomical structure development

[Term]
id: GO:0007346
name: regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "mitotic cell cycle modulation" EXACT []
synonym: "mitotic cell cycle regulation" EXACT []
synonym: "mitotic cell cycle regulator" RELATED []
synonym: "modulation of mitotic cell cycle progression" EXACT []
synonym: "regulation of mitotic cell cycle progression" EXACT []
synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0000278 ! mitotic cell cycle
relationship: regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0007369
name: gastrulation
namespace: biological_process
def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846]
xref: MIPS_funcat:41.05.09
xref: Wikipedia:Gastrulation
is_a: GO:0048598 ! embryonic morphogenesis
relationship: has_part GO:0001705 ! ectoderm formation
relationship: has_part GO:0001706 ! endoderm formation
relationship: has_part GO:0001707 ! mesoderm formation

[Term]
id: GO:0007389
name: pattern specification process
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125]
synonym: "pattern biosynthesis" RELATED []
synonym: "pattern formation" RELATED []
xref: MIPS_funcat:41.01.03
is_a: GO:0032501 ! multicellular organismal process
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0007398
name: ectoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb]
is_a: GO:0009888 ! tissue development

[Term]
id: GO:0007399
name: nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh]
synonym: "pan-neural process" RELATED []
xref: MIPS_funcat:45.03.17
xref: MIPS_funcat:47.03.01
is_a: GO:0048731 ! system development

[Term]
id: GO:0007492
name: endoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb]
is_a: GO:0009888 ! tissue development

[Term]
id: GO:0007498
name: mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb]
is_a: GO:0009888 ! tissue development

[Term]
id: GO:0007610
name: behavior
namespace: biological_process
alt_id: GO:0044708
def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973]
comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_flybase_ribbon
synonym: "behavioral response to stimulus" EXACT []
synonym: "behaviour" EXACT []
synonym: "behavioural response to stimulus" EXACT []
synonym: "single-organism behavior" RELATED []
xref: Wikipedia:Behavior
is_a: GO:0050896 ! response to stimulus
disjoint_from: GO:0032502 ! developmental process
created_by: janelomax
creation_date: 2012-09-20T14:06:08Z

[Term]
id: GO:0008150
name: biological_process
namespace: biological_process
alt_id: GO:0000004
alt_id: GO:0007582
alt_id: GO:0044699
def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_yeast
synonym: "biological process" EXACT []
synonym: "physiological process" EXACT []
synonym: "single organism process" RELATED []
synonym: "single-organism process" RELATED []
xref: Wikipedia:Biological_process
is_a: BFO:0000015 ! process
created_by: janelomax
creation_date: 2012-09-19T15:05:24Z

[Term]
id: GO:0008152
name: metabolic process
namespace: biological_process
alt_id: GO:0044236
alt_id: GO:0044710
def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684]
comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
subset: gocheck_do_not_manually_annotate
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "metabolic process resulting in cell growth" NARROW []
synonym: "metabolism" EXACT []
synonym: "metabolism resulting in cell growth" NARROW []
synonym: "multicellular organism metabolic process" NARROW []
synonym: "single-organism metabolic process" RELATED []
xref: MIPS_funcat:01
xref: Wikipedia:Metabolism
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-10-17T15:46:40Z

[Term]
id: GO:0008283
name: cell population proliferation
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb]
comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
synonym: "cell proliferation" RELATED []
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0008284
name: positive regulation of cell population proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators]
synonym: "activation of cell proliferation" NARROW []
synonym: "positive regulation of cell proliferation" RELATED []
synonym: "stimulation of cell proliferation" NARROW []
synonym: "up regulation of cell proliferation" EXACT []
synonym: "up-regulation of cell proliferation" EXACT []
synonym: "upregulation of cell proliferation" EXACT []
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0008283 ! cell population proliferation
relationship: positively_regulates GO:0008283 ! cell population proliferation

[Term]
id: GO:0008285
name: negative regulation of cell population proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators]
synonym: "down regulation of cell proliferation" EXACT []
synonym: "down-regulation of cell proliferation" EXACT []
synonym: "downregulation of cell proliferation" EXACT []
synonym: "inhibition of cell proliferation" NARROW []
synonym: "negative regulation of cell proliferation" RELATED []
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0008283 ! cell population proliferation
relationship: negatively_regulates GO:0008283 ! cell population proliferation

[Term]
id: GO:0009605
name: response to external stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_plant
synonym: "response to environmental stimulus" EXACT []
xref: MIPS_funcat:36.20.35
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0009611
name: response to wounding
namespace: biological_process
alt_id: GO:0002245
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." [GOC:go_curators]
synonym: "physiological response to wounding" EXACT []
is_a: GO:0006950 ! response to stress

[Term]
id: GO:0009653
name: anatomical structure morphogenesis
namespace: biological_process
def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125]
synonym: "anatomical structure organization" EXACT []
synonym: "embryogenesis and morphogenesis" BROAD []
synonym: "morphogenesis" EXACT []
xref: Wikipedia:Morphogenesis
is_a: GO:0032502 ! developmental process
relationship: part_of GO:0048856 ! anatomical structure development

[Term]
id: GO:0009790
name: embryo development
namespace: biological_process
alt_id: GO:0009795
def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu]
subset: gocheck_do_not_manually_annotate
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
synonym: "embryogenesis" EXACT []
synonym: "embryogenesis and morphogenesis" BROAD []
synonym: "embryonal development" EXACT []
xref: Wikipedia:Embryogenesis
is_a: GO:0007275 ! multicellular organism development

[Term]
id: GO:0009798
name: axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete]
synonym: "axis determination" RELATED []
xref: MIPS_funcat:41.05.19
is_a: GO:0007389 ! pattern specification process

[Term]
id: GO:0009888
name: tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208]
synonym: "histogenesis" EXACT []
synonym: "histogenesis and organogenesis" BROAD []
xref: Wikipedia:Histogenesis
is_a: GO:0048856 ! anatomical structure development

[Term]
id: GO:0009892
name: negative regulation of metabolic process
namespace: biological_process
alt_id: GO:0044252
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "down regulation of metabolic process" EXACT []
synonym: "down-regulation of metabolic process" EXACT []
synonym: "downregulation of metabolic process" EXACT []
synonym: "inhibition of metabolic process" NARROW []
synonym: "inhibition of organismal metabolic process" NARROW []
synonym: "negative regulation of metabolism" EXACT []
synonym: "negative regulation of multicellular organismal metabolic process" NARROW []
synonym: "negative regulation of organismal metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0008152 ! metabolic process
relationship: negatively_regulates GO:0008152 ! metabolic process

[Term]
id: GO:0009893
name: positive regulation of metabolic process
namespace: biological_process
alt_id: GO:0044253
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "activation of metabolic process" NARROW []
synonym: "positive regulation of metabolism" EXACT []
synonym: "positive regulation of multicellular organismal metabolic process" NARROW []
synonym: "positive regulation of organismal metabolism" NARROW []
synonym: "stimulation of metabolic process" NARROW []
synonym: "stimulation of organismal metabolic process" NARROW []
synonym: "up regulation of metabolic process" EXACT []
synonym: "up-regulation of metabolic process" EXACT []
synonym: "up-regulation of organismal metabolic process" NARROW []
synonym: "upregulation of metabolic process" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0008152 ! metabolic process
relationship: positively_regulates GO:0008152 ! metabolic process

[Term]
id: GO:0009946
name: proximal/distal axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "proximal/distal axis determination" RELATED [GOC:dph]
synonym: "proximodistal axis specification" EXACT []
is_a: GO:0009798 ! axis specification
relationship: part_of GO:0009954 ! proximal/distal pattern formation

[Term]
id: GO:0009948
name: anterior/posterior axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "anterior/posterior axis determination" RELATED [GOC:dph]
xref: MIPS_funcat:41.05.19.05
is_a: GO:0009798 ! axis specification
relationship: part_of GO:0009952 ! anterior/posterior pattern specification

[Term]
id: GO:0009950
name: dorsal/ventral axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "dorsal-ventral axis specification" EXACT [GOC:mah]
synonym: "dorsal/ventral axis determination" RELATED [GOC:dph]
synonym: "dorsoventral axis specification" EXACT [GOC:mah]
xref: MIPS_funcat:41.05.19.07
is_a: GO:0009798 ! axis specification
relationship: part_of GO:0009953 ! dorsal/ventral pattern formation

[Term]
id: GO:0009952
name: anterior/posterior pattern specification
namespace: biological_process
def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
synonym: "anterior/posterior pattern formation" RELATED []
is_a: GO:0003002 ! regionalization

[Term]
id: GO:0009953
name: dorsal/ventral pattern formation
namespace: biological_process
def: "The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
synonym: "dorsal-ventral pattern formation" EXACT [GOC:mah]
synonym: "dorsal/ventral pattern specification" NARROW []
synonym: "dorsoventral pattern formation" EXACT [GOC:mah]
is_a: GO:0003002 ! regionalization

[Term]
id: GO:0009954
name: proximal/distal pattern formation
namespace: biological_process
def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)." [GOC:dph, GOC:go_curators, GOC:isa_complete]
synonym: "proximal/distal pattern specification" NARROW []
is_a: GO:0003002 ! regionalization

[Term]
id: GO:0009966
name: regulation of signal transduction
namespace: biological_process
alt_id: GO:0035466
def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "regulation of signaling pathway" RELATED []
synonym: "regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007165 ! signal transduction
relationship: regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009967
name: positive regulation of signal transduction
namespace: biological_process
alt_id: GO:0035468
def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "activation of signal transduction" NARROW []
synonym: "positive regulation of signaling pathway" RELATED []
synonym: "positive regulation of signalling pathway" RELATED [GOC:mah]
synonym: "stimulation of signal transduction" NARROW []
synonym: "up regulation of signal transduction" EXACT []
synonym: "up-regulation of signal transduction" EXACT []
synonym: "upregulation of signal transduction" EXACT []
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007165 ! signal transduction
relationship: positively_regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009968
name: negative regulation of signal transduction
namespace: biological_process
alt_id: GO:0035467
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "down regulation of signal transduction" EXACT []
synonym: "down-regulation of signal transduction" EXACT []
synonym: "downregulation of signal transduction" EXACT []
synonym: "inhibition of signal transduction" NARROW []
synonym: "negative regulation of signaling pathway" RELATED []
synonym: "negative regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007165 ! signal transduction
relationship: negatively_regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009987
name: cellular process
namespace: biological_process
alt_id: GO:0008151
alt_id: GO:0044763
alt_id: GO:0050875
def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete]
subset: goslim_plant
synonym: "cell growth and/or maintenance" NARROW []
synonym: "cell physiology" EXACT []
synonym: "cellular physiological process" EXACT []
synonym: "single-organism cellular process" RELATED []
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-12-11T16:56:55Z

[Term]
id: GO:0010469
name: regulation of signaling receptor activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity." [GOC:dph, GOC:tb]
synonym: "regulation of receptor activity" BROAD []
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0038023 ! signaling receptor activity
relationship: regulates GO:0038023 ! signaling receptor activity

[Term]
id: GO:0010470
name: regulation of gastrulation
namespace: biological_process
def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0045995 ! regulation of embryonic development
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007369 ! gastrulation
relationship: regulates GO:0007369 ! gastrulation

[Term]
id: GO:0010562
name: positive regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process
relationship: positively_regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0010563
name: negative regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process
relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0010564
name: regulation of cell cycle process
namespace: biological_process
def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0022402 ! cell cycle process
relationship: regulates GO:0022402 ! cell cycle process

[Term]
id: GO:0010638
name: positive regulation of organelle organization
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb]
synonym: "positive regulation of organelle organisation" EXACT [GOC:mah]
synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0006996 ! organelle organization
relationship: positively_regulates GO:0006996 ! organelle organization

[Term]
id: GO:0010639
name: negative regulation of organelle organization
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb]
synonym: "negative regulation of organelle organisation" EXACT [GOC:mah]
synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0006996 ! organelle organization
relationship: negatively_regulates GO:0006996 ! organelle organization

[Term]
id: GO:0010646
name: regulation of cell communication
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007154 ! cell communication
relationship: regulates GO:0007154 ! cell communication

[Term]
id: GO:0010647
name: positive regulation of cell communication
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007154 ! cell communication
relationship: positively_regulates GO:0007154 ! cell communication

[Term]
id: GO:0010648
name: negative regulation of cell communication
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007154 ! cell communication
relationship: negatively_regulates GO:0007154 ! cell communication

[Term]
id: GO:0010720
name: positive regulation of cell development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0048468 ! cell development
relationship: positively_regulates GO:0048468 ! cell development

[Term]
id: GO:0010721
name: negative regulation of cell development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0048468 ! cell development
relationship: negatively_regulates GO:0048468 ! cell development

[Term]
id: GO:0010927
name: cellular component assembly involved in morphogenesis
namespace: biological_process
def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0032989 ! cellular component morphogenesis

[Term]
id: GO:0010948
name: negative regulation of cell cycle process
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0045786 ! negative regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0022402 ! cell cycle process
relationship: negatively_regulates GO:0022402 ! cell cycle process
created_by: tanyaberardini
creation_date: 2009-04-27T09:53:22Z

[Term]
id: GO:0010975
name: regulation of neuron projection development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "regulation of neurite development" NARROW [GOC:mah]
synonym: "regulation of neurite formation" NARROW [GOC:mah]
synonym: "regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0045664 ! regulation of neuron differentiation
is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0031175 ! neuron projection development
relationship: regulates GO:0031175 ! neuron projection development
created_by: tanyaberardini
creation_date: 2009-06-01T10:44:45Z

[Term]
id: GO:0010976
name: positive regulation of neuron projection development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "positive regulation of neurite development" NARROW [GOC:mah]
synonym: "positive regulation of neurite formation" NARROW [GOC:mah]
synonym: "positive regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0010975 ! regulation of neuron projection development
is_a: GO:0031346 ! positive regulation of cell projection organization
is_a: GO:0045666 ! positive regulation of neuron differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0031175 ! neuron projection development
relationship: positively_regulates GO:0031175 ! neuron projection development
created_by: tanyaberardini
creation_date: 2009-06-01T10:46:44Z

[Term]
id: GO:0010977
name: negative regulation of neuron projection development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "growth cone collapse" RELATED [GOC:pr]
synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "negative regulation of neurite development" NARROW [GOC:mah]
synonym: "negative regulation of neurite formation" NARROW [GOC:mah]
synonym: "negative regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0010975 ! regulation of neuron projection development
is_a: GO:0031345 ! negative regulation of cell projection organization
is_a: GO:0045665 ! negative regulation of neuron differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0031175 ! neuron projection development
relationship: negatively_regulates GO:0031175 ! neuron projection development
created_by: tanyaberardini
creation_date: 2009-06-01T10:47:42Z

[Term]
id: GO:0012505
name: endomembrane system
namespace: cellular_component
def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_flybase_ribbon
subset: goslim_yeast
xref: Wikipedia:Endomembrane_system
is_a: GO:0044464 ! cell part
relationship: has_part GO:0005773 ! vacuole
relationship: has_part GO:0005886 ! plasma membrane

[Term]
id: GO:0015629
name: actin cytoskeleton
namespace: cellular_component
def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194]
subset: goslim_aspergillus
xref: MIPS_funcat:70.04.03
is_a: GO:0005856 ! cytoskeleton

[Term]
id: GO:0015630
name: microtubule cytoskeleton
namespace: cellular_component
def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172]
subset: goslim_aspergillus
xref: MIPS_funcat:70.04.05
is_a: GO:0005856 ! cytoskeleton

[Term]
id: GO:0016020
name: membrane
namespace: cellular_component
def: "A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
xref: Wikipedia:Biological_membrane
is_a: CARO:0000014 ! cell part
is_a: GO:0005575 ! cellular_component
property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl

[Term]
id: GO:0016043
name: cellular component organization
namespace: biological_process
alt_id: GO:0044235
alt_id: GO:0071842
def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah]
subset: goslim_agr
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
synonym: "cell organisation" EXACT []
synonym: "cell organization and biogenesis" RELATED [GOC:mah]
synonym: "cellular component organisation at cellular level" EXACT [GOC:mah]
synonym: "cellular component organisation in other organism" EXACT [GOC:mah]
synonym: "cellular component organization at cellular level" EXACT []
synonym: "cellular component organization in other organism" EXACT []
xref: MIPS_funcat:42
is_a: GO:0009987 ! cellular process
is_a: GO:0071840 ! cellular component organization or biogenesis

[Term]
id: GO:0016301
name: kinase activity
namespace: molecular_function
def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732]
comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
subset: goslim_yeast
synonym: "phosphokinase activity" EXACT []
xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm"
xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
relationship: part_of GO:0016310 ! phosphorylation

[Term]
id: GO:0016310
name: phosphorylation
namespace: biological_process
def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732]
subset: goslim_chembl
subset: goslim_metagenomics
xref: Wikipedia:Phosphorylation
is_a: GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0016477
name: cell migration
namespace: biological_process
def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, http://en.wikipedia.org/wiki/Cell_migration]
xref: MIPS_funcat:34.05.01
xref: Wikipedia:Cell_migration
is_a: GO:0048870 ! cell motility

[Term]
id: GO:0016740
name: transferase activity
namespace: molecular_function
def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
xref: EC:2
xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2"
xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1"
xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK"
xref: Reactome:R-HSA-6787403 "GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA"
xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248"
is_a: GO:0003824 ! catalytic activity

[Term]
id: GO:0016772
name: transferase activity, transferring phosphorus-containing groups
namespace: molecular_function
def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732]
comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
subset: goslim_chembl
xref: EC:2.7
is_a: GO:0016740 ! transferase activity

[Term]
id: GO:0017145
name: stem cell division
namespace: biological_process
def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089]
synonym: "stem cell renewal" EXACT []
is_a: GO:0051301 ! cell division

[Term]
id: GO:0019098
name: reproductive behavior
namespace: biological_process
alt_id: GO:0033057
alt_id: GO:0044704
def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr]
synonym: "multicellular organism reproductive behavior" NARROW []
synonym: "reproductive behavior in a multicellular organism" EXACT [GOC:curators]
synonym: "reproductive behaviour" EXACT []
synonym: "single-organism reproductive behavior" RELATED []
is_a: GO:0007610 ! behavior
is_a: GO:0048609 ! multicellular organismal reproductive process
intersection_of: GO:0007610 ! behavior
intersection_of: part_of GO:0000003 ! reproduction
created_by: janelomax
creation_date: 2012-09-19T16:01:37Z

[Term]
id: GO:0019220
name: regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "regulation of phosphate metabolism" EXACT []
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0019222
name: regulation of metabolic process
namespace: biological_process
alt_id: GO:0044246
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
subset: goslim_metagenomics
synonym: "regulation of metabolism" EXACT []
synonym: "regulation of multicellular organismal metabolic process" NARROW []
synonym: "regulation of organismal metabolic process" NARROW [GOC:tb]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0008152 ! metabolic process
relationship: regulates GO:0008152 ! metabolic process

[Term]
id: GO:0019226
name: transmission of nerve impulse
namespace: biological_process
def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194]
synonym: "conduction of nerve impulse" EXACT [GOC:dph]
synonym: "signal transmission along a neuron" EXACT []
is_a: GO:0035637 ! multicellular organismal signaling
is_a: GO:0050877 ! nervous system process
relationship: has_part GO:0001508 ! action potential
relationship: has_part GO:0007268 ! chemical synaptic transmission
relationship: part_of GO:0007154 ! cell communication

[Term]
id: GO:0022008
name: neurogenesis
namespace: biological_process
def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06]
comment: This term was added by GO_REF:0000021.
synonym: "nervous system cell generation" EXACT systematic_synonym []
synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph]
xref: Wikipedia:Neurogenesis
is_a: GO:0030154 ! cell differentiation
relationship: part_of GO:0007399 ! nervous system development

[Term]
id: GO:0022402
name: cell cycle process
namespace: biological_process
def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle]
subset: gocheck_do_not_annotate
is_a: GO:0009987 ! cellular process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0007049 ! cell cycle
relationship: part_of GO:0007049 ! cell cycle

[Term]
id: GO:0022412
name: cellular process involved in reproduction in multicellular organism
namespace: biological_process
def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete]
synonym: "reproductive cellular process in multicellular organism" EXACT [GOC:curators]
is_a: GO:0009987 ! cellular process
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0032504 ! multicellular organism reproduction
relationship: part_of GO:0032504 ! multicellular organism reproduction

[Term]
id: GO:0022414
name: reproductive process
namespace: biological_process
alt_id: GO:0044702
def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete]
synonym: "single organism reproductive process" RELATED []
is_a: GO:0008150 ! biological_process
intersection_of: GO:0008150 ! biological_process
intersection_of: part_of GO:0000003 ! reproduction
relationship: part_of GO:0000003 ! reproduction
created_by: janelomax
creation_date: 2012-09-19T15:56:06Z

[Term]
id: GO:0022603
name: regulation of anatomical structure morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah]
synonym: "regulation of morphogenesis" EXACT []
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0009653 ! anatomical structure morphogenesis
relationship: regulates GO:0009653 ! anatomical structure morphogenesis

[Term]
id: GO:0022607
name: cellular component assembly
namespace: biological_process
alt_id: GO:0071844
def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
synonym: "cell structure assembly" EXACT []
synonym: "cellular component assembly at cellular level" EXACT []
is_a: GO:0016043 ! cellular component organization
relationship: part_of GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0023051
name: regulation of signaling
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "regulation of signaling process" RELATED [GOC:bf]
synonym: "regulation of signalling process" RELATED [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0023052 ! signaling
relationship: regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023052
name: signaling
namespace: biological_process
alt_id: GO:0023046
alt_id: GO:0044700
def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling]
comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pombe
subset: goslim_yeast
synonym: "biological signaling" EXACT []
synonym: "signaling process" EXACT []
synonym: "signalling" EXACT []
synonym: "signalling process" RELATED [GOC:mah]
synonym: "single organism signaling" RELATED []
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023056
name: positive regulation of signaling
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "positive regulation of signaling process" RELATED [GOC:bf]
synonym: "positive regulation of signalling process" EXACT [GOC:mah]
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0023052 ! signaling
relationship: positively_regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023057
name: negative regulation of signaling
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "negative regulation of signaling process" RELATED [GOC:bf]
synonym: "negative regulation of signalling process" RELATED [GOC:mah]
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0023052 ! signaling
relationship: negatively_regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0030016
name: myofibril
namespace: cellular_component
def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194]
synonym: "striated muscle fiber" RELATED []
synonym: "striated muscle fibre" RELATED []
xref: Wikipedia:Myofibril
is_a: GO:0043292 ! contractile fiber

[Term]
id: GO:0030017
name: sarcomere
namespace: cellular_component
def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194]
xref: Wikipedia:Sarcomere
is_a: GO:0044449 ! contractile fiber part
relationship: part_of GO:0030016 ! myofibril

[Term]
id: GO:0030029
name: actin filament-based process
namespace: biological_process
def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah]
synonym: "microfilament-based process" RELATED []
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0030030
name: cell projection organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/]
synonym: "cell projection organisation" EXACT [GOC:curators]
synonym: "cell projection organization and biogenesis" RELATED [GOC:mah]
synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016043 ! cellular component organization

[Term]
id: GO:0030036
name: actin cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pombe
synonym: "actin cytoskeleton organisation" EXACT [GOC:curators]
synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah]
synonym: "actin modulating activity" RELATED []
xref: MIPS_funcat:42.04.03
is_a: GO:0007010 ! cytoskeleton organization
is_a: GO:0030029 ! actin filament-based process

[Term]
id: GO:0030141
name: secretory granule
namespace: cellular_component
def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732]
comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.
synonym: "secretory vesicle" BROAD []
is_a: GO:0099503 ! secretory vesicle
relationship: part_of GO:0012505 ! endomembrane system

[Term]
id: GO:0030154
name: cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_generic
subset: goslim_mouse
subset: goslim_plant
xref: MIPS_funcat:40.02
xref: Wikipedia:Cellular_differentiation
is_a: GO:0048869 ! cellular developmental process

[Term]
id: GO:0030182
name: neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah]
xref: MIPS_funcat:43.03.13
is_a: GO:0030154 ! cell differentiation
relationship: part_of GO:0048699 ! generation of neurons

[Term]
id: GO:0030239
name: myofibril assembly
namespace: biological_process
def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah]
is_a: GO:0010927 ! cellular component assembly involved in morphogenesis
is_a: GO:0031032 ! actomyosin structure organization
is_a: GO:0070925 ! organelle assembly
is_a: GO:0097435 ! supramolecular fiber organization
relationship: part_of GO:0055002 ! striated muscle cell development

[Term]
id: GO:0030334
name: regulation of cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators]
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0016477 ! cell migration
relationship: regulates GO:0016477 ! cell migration

[Term]
id: GO:0030335
name: positive regulation of cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators]
synonym: "activation of cell migration" NARROW []
synonym: "stimulation of cell migration" NARROW []
synonym: "up regulation of cell migration" EXACT []
synonym: "up-regulation of cell migration" EXACT []
synonym: "upregulation of cell migration" EXACT []
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:2000147 ! positive regulation of cell motility
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0016477 ! cell migration
relationship: positively_regulates GO:0016477 ! cell migration

[Term]
id: GO:0030336
name: negative regulation of cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators]
synonym: "down regulation of cell migration" EXACT []
synonym: "down-regulation of cell migration" EXACT []
synonym: "downregulation of cell migration" EXACT []
synonym: "inhibition of cell migration" NARROW []
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:2000146 ! negative regulation of cell motility
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0016477 ! cell migration
relationship: negatively_regulates GO:0016477 ! cell migration

[Term]
id: GO:0030545
name: receptor regulator activity
namespace: molecular_function
def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed." [GOC:ceb]
xref: MIPS_funcat:18.02.07
is_a: GO:0098772 ! molecular function regulator

[Term]
id: GO:0030546
name: signaling receptor activator activity
namespace: molecular_function
def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased." [GOC:ceb]
synonym: "receptor activator activity" BROAD []
is_a: GO:0030545 ! receptor regulator activity

[Term]
id: GO:0031032
name: actomyosin structure organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah]
comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.
synonym: "actomyosin organization" EXACT []
synonym: "actomyosin structure organisation" EXACT [GOC:curators]
synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0030036 ! actin cytoskeleton organization

[Term]
id: GO:0031045
name: dense core granule
namespace: cellular_component
def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495]
synonym: "dense core vesicle" EXACT syngo_official_label [GOC:kmv]
xref: NIF_Subcellular:sao772007592
is_a: GO:0030141 ! secretory granule

[Term]
id: GO:0031099
name: regeneration
namespace: biological_process
def: "The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass)." [GOC:mah, GOC:pr]
xref: Wikipedia:Regeneration_(biology)
is_a: GO:0048856 ! anatomical structure development

[Term]
id: GO:0031102
name: neuron projection regeneration
namespace: biological_process
def: "The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage." [GOC:dgh, GOC:dph, GOC:tb]
synonym: "neurite regeneration" NARROW [GOC:mah]
is_a: GO:0031099 ! regeneration
is_a: GO:0031175 ! neuron projection development
is_a: GO:0033554 ! cellular response to stress

[Term]
id: GO:0031103
name: axon regeneration
namespace: biological_process
def: "The regrowth of axons following their loss or damage." [GOC:dgh, GOC:dph, GOC:tb]
is_a: GO:0031102 ! neuron projection regeneration
is_a: GO:0048678 ! response to axon injury
is_a: GO:0061564 ! axon development

[Term]
id: GO:0031175
name: neuron projection development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah]
synonym: "neurite biosynthesis" NARROW []
synonym: "neurite development" NARROW [GOC:dph]
synonym: "neurite formation" NARROW []
synonym: "neurite growth" NARROW []
synonym: "neurite outgrowth" NARROW []
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: part_of GO:0048666 ! neuron development
relationship: part_of GO:0048666 ! neuron development

[Term]
id: GO:0031323
name: regulation of cellular metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
synonym: "regulation of cellular metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0044237 ! cellular metabolic process
relationship: regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031324
name: negative regulation of cellular metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
synonym: "down regulation of cellular metabolic process" EXACT []
synonym: "down-regulation of cellular metabolic process" EXACT []
synonym: "downregulation of cellular metabolic process" EXACT []
synonym: "inhibition of cellular metabolic process" NARROW []
synonym: "negative regulation of cellular metabolism" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0044237 ! cellular metabolic process
relationship: negatively_regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031325
name: positive regulation of cellular metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
synonym: "activation of cellular metabolic process" NARROW []
synonym: "positive regulation of cellular metabolism" EXACT []
synonym: "stimulation of cellular metabolic process" NARROW []
synonym: "up regulation of cellular metabolic process" EXACT []
synonym: "up-regulation of cellular metabolic process" EXACT []
synonym: "upregulation of cellular metabolic process" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0044237 ! cellular metabolic process
relationship: positively_regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031344
name: regulation of cell projection organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "regulation of cell projection organisation" EXACT [GOC:curators]
synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0030030 ! cell projection organization
relationship: regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031345
name: negative regulation of cell projection organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "down regulation of cell projection organization" EXACT [GOC:mah]
synonym: "down-regulation of cell projection organization" EXACT []
synonym: "downregulation of cell projection organization" EXACT []
synonym: "inhibition of cell projection organization" NARROW []
synonym: "negative regulation of cell projection organisation" EXACT [GOC:curators]
synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0031344 ! regulation of cell projection organization
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0030030 ! cell projection organization
relationship: negatively_regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031346
name: positive regulation of cell projection organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "activation of cell projection organization" NARROW []
synonym: "positive regulation of cell projection organisation" EXACT [GOC:curators]
synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cell projection organization" NARROW []
synonym: "up regulation of cell projection organization" EXACT []
synonym: "up-regulation of cell projection organization" EXACT []
synonym: "upregulation of cell projection organization" EXACT []
is_a: GO:0031344 ! regulation of cell projection organization
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0030030 ! cell projection organization
relationship: positively_regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031410
name: cytoplasmic vesicle
namespace: cellular_component
alt_id: GO:0016023
def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_mouse
subset: goslim_yeast
synonym: "cytoplasmic membrane bounded vesicle" RELATED []
synonym: "cytoplasmic membrane-enclosed vesicle" RELATED []
synonym: "cytoplasmic, membrane-bounded vesicle" RELATED []
xref: NIF_Subcellular:sao180601769
is_a: GO:0044444 ! cytoplasmic part
is_a: GO:0097708 ! intracellular vesicle
intersection_of: GO:0031982 ! vesicle
intersection_of: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0031644
name: regulation of neurological system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system." [GOC:dph, GOC:mah, GOC:tb]
synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of neurophysiological process" EXACT []
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0050877 ! nervous system process
relationship: regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031645
name: negative regulation of neurological system process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]
synonym: "down regulation of neurological process" EXACT []
synonym: "down-regulation of neurological process" EXACT []
synonym: "downregulation of neurological process" EXACT []
synonym: "inhibition of neurological process" NARROW []
synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of neurophysiological process" EXACT []
is_a: GO:0031644 ! regulation of neurological system process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0050877 ! nervous system process
relationship: negatively_regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031646
name: positive regulation of neurological system process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]
synonym: "activation of neurological process" NARROW []
synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of neurophysiological process" EXACT []
synonym: "stimulation of neurological process" NARROW []
synonym: "up regulation of neurological process" EXACT []
synonym: "up-regulation of neurological process" EXACT []
synonym: "upregulation of neurological process" EXACT []
is_a: GO:0031644 ! regulation of neurological system process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0050877 ! nervous system process
relationship: positively_regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031941
name: filamentous actin
namespace: cellular_component
def: "A two-stranded helical polymer of the protein actin." [GOC:mah]
comment: Note that this term refers only to the actin portion of a microfilament, and does not encompass associated proteins. See also the cellular component term 'actin filament ; GO:0005884'.
synonym: "F-actin" EXACT []
xref: Wikipedia:Actin
is_a: GO:0032991 ! protein-containing complex
is_a: GO:0044430 ! cytoskeletal part
relationship: part_of GO:0005884 ! actin filament

[Term]
id: GO:0031982
name: vesicle
namespace: cellular_component
alt_id: GO:0031988
def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles]
subset: goslim_pir
synonym: "membrane-bounded vesicle" RELATED []
synonym: "membrane-enclosed vesicle" RELATED []
xref: NIF_Subcellular:sao221389602
xref: Wikipedia:Vesicle_(biology)
is_a: GO:0043227 ! membrane-bounded organelle

[Term]
id: GO:0032091
name: negative regulation of protein binding
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." [GOC:mah]
synonym: "down regulation of protein binding" EXACT []
synonym: "down-regulation of protein binding" EXACT []
synonym: "downregulation of protein binding" EXACT []
synonym: "inhibition of protein binding" NARROW []
is_a: GO:0043393 ! regulation of protein binding
is_a: GO:0051100 ! negative regulation of binding
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0005515 ! protein binding
relationship: negatively_regulates GO:0005515 ! protein binding

[Term]
id: GO:0032092
name: positive regulation of protein binding
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein binding." [GOC:mah]
synonym: "activation of protein binding" NARROW []
synonym: "stimulation of protein binding" NARROW []
synonym: "up regulation of protein binding" EXACT []
synonym: "up-regulation of protein binding" EXACT []
synonym: "upregulation of protein binding" EXACT []
is_a: GO:0043393 ! regulation of protein binding
is_a: GO:0051099 ! positive regulation of binding
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0005515 ! protein binding
relationship: positively_regulates GO:0005515 ! protein binding

[Term]
id: GO:0032101
name: regulation of response to external stimulus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0009605 ! response to external stimulus
relationship: regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032102
name: negative regulation of response to external stimulus
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of response to external stimulus" EXACT []
synonym: "down-regulation of response to external stimulus" EXACT []
synonym: "downregulation of response to external stimulus" EXACT []
synonym: "inhibition of response to external stimulus" NARROW []
is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0009605 ! response to external stimulus
relationship: negatively_regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032103
name: positive regulation of response to external stimulus
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "activation of response to external stimulus" NARROW []
synonym: "stimulation of response to external stimulus" NARROW []
synonym: "up regulation of response to external stimulus" EXACT []
synonym: "up-regulation of response to external stimulus" EXACT []
synonym: "upregulation of response to external stimulus" EXACT []
is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0009605 ! response to external stimulus
relationship: positively_regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032465
name: regulation of cytokinesis
namespace: biological_process
alt_id: GO:0071775
def: "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:mah]
synonym: "regulation of cell cycle cytokinesis" EXACT []
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0000910 ! cytokinesis
relationship: regulates GO:0000910 ! cytokinesis

[Term]
id: GO:0032466
name: negative regulation of cytokinesis
namespace: biological_process
alt_id: GO:0071776
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah]
synonym: "down regulation of cytokinesis" EXACT []
synonym: "down-regulation of cytokinesis" EXACT []
synonym: "downregulation of cytokinesis" EXACT []
synonym: "inhibition of cytokinesis" NARROW []
synonym: "negative regulation of cell cycle cytokinesis" RELATED []
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0032465 ! regulation of cytokinesis
is_a: GO:0051782 ! negative regulation of cell division
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0000910 ! cytokinesis
relationship: negatively_regulates GO:0000910 ! cytokinesis

[Term]
id: GO:0032467
name: positive regulation of cytokinesis
namespace: biological_process
alt_id: GO:0071777
def: "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah]
synonym: "activation of cytokinesis" NARROW []
synonym: "positive regulation of cell cycle cytokinesis" RELATED []
synonym: "stimulation of cytokinesis" NARROW []
synonym: "up regulation of cytokinesis" EXACT []
synonym: "up-regulation of cytokinesis" EXACT []
synonym: "upregulation of cytokinesis" EXACT []
is_a: GO:0032465 ! regulation of cytokinesis
is_a: GO:0051781 ! positive regulation of cell division
is_a: GO:0090068 ! positive regulation of cell cycle process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0000910 ! cytokinesis
relationship: positively_regulates GO:0000910 ! cytokinesis

[Term]
id: GO:0032501
name: multicellular organismal process
namespace: biological_process
alt_id: GO:0044707
alt_id: GO:0050874
def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb]
subset: goslim_pir
synonym: "organismal physiological process" EXACT []
synonym: "single-multicellular organism process" RELATED []
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-09-19T16:07:47Z

[Term]
id: GO:0032502
name: developmental process
namespace: biological_process
alt_id: GO:0044767
def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete]
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_flybase_ribbon
subset: goslim_pir
synonym: "development" NARROW []
synonym: "single-organism developmental process" RELATED []
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-12-19T12:21:31Z

[Term]
id: GO:0032504
name: multicellular organism reproduction
namespace: biological_process
def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid]
is_a: GO:0000003 ! reproduction
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0032879
name: regulation of localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah]
synonym: "regulation of localisation" EXACT [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0051179 ! localization
relationship: regulates GO:0051179 ! localization

[Term]
id: GO:0032956
name: regulation of actin cytoskeleton organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah]
synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah]
synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0032970 ! regulation of actin filament-based process
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0030036 ! actin cytoskeleton organization
relationship: regulates GO:0030036 ! actin cytoskeleton organization

[Term]
id: GO:0032970
name: regulation of actin filament-based process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0030029 ! actin filament-based process
relationship: regulates GO:0030029 ! actin filament-based process

[Term]
id: GO:0032989
name: cellular component morphogenesis
namespace: biological_process
def: "The process in which cellular structures, including whole cells or cell parts, are generated and organized." [GOC:dph, GOC:mah, GOC:tb]
subset: goslim_pir
synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009653 ! anatomical structure morphogenesis
is_a: GO:0016043 ! cellular component organization
is_a: GO:0048869 ! cellular developmental process

[Term]
id: GO:0032991
name: protein-containing complex
namespace: cellular_component
alt_id: GO:0043234
def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah]
comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_pir
synonym: "macromolecular complex" EXACT []
synonym: "macromolecule complex" EXACT []
synonym: "protein complex" NARROW []
synonym: "protein containing complex" EXACT []
synonym: "protein-protein complex" NARROW []
is_a: GO:0005575 ! cellular_component

[Term]
id: GO:0033043
name: regulation of organelle organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah]
subset: goslim_yeast
synonym: "regulation of organelle organisation" EXACT [GOC:mah]
synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0006996 ! organelle organization
relationship: regulates GO:0006996 ! organelle organization

[Term]
id: GO:0033554
name: cellular response to stress
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0006950 ! response to stress
is_a: GO:0051716 ! cellular response to stimulus

[Term]
id: GO:0033673
name: negative regulation of kinase activity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah]
synonym: "down regulation of kinase activity" EXACT []
synonym: "down-regulation of kinase activity" EXACT []
synonym: "downregulation of kinase activity" EXACT []
synonym: "inhibition of kinase activity" NARROW []
synonym: "kinase inhibitor" NARROW []
is_a: GO:0042326 ! negative regulation of phosphorylation
is_a: GO:0043549 ! regulation of kinase activity
is_a: GO:0051348 ! negative regulation of transferase activity
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0016301 ! kinase activity
relationship: negatively_regulates GO:0016301 ! kinase activity

[Term]
id: GO:0033674
name: positive regulation of kinase activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah]
synonym: "kinase activator" NARROW []
synonym: "stimulation of kinase activity" NARROW []
synonym: "up regulation of kinase activity" EXACT []
synonym: "up-regulation of kinase activity" EXACT []
synonym: "upregulation of kinase activity" EXACT []
is_a: GO:0042327 ! positive regulation of phosphorylation
is_a: GO:0043549 ! regulation of kinase activity
is_a: GO:0051347 ! positive regulation of transferase activity
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0016301 ! kinase activity
relationship: positively_regulates GO:0016301 ! kinase activity

[Term]
id: GO:0035187
name: hatching behavior
namespace: biological_process
def: "The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell." [GOC:pr, PMID:10436051]
synonym: "hatching behaviour" EXACT []
is_a: GO:0007610 ! behavior
is_a: GO:0032501 ! multicellular organismal process
relationship: part_of GO:0035188 ! hatching

[Term]
id: GO:0035188
name: hatching
namespace: biological_process
def: "The emergence of an immature organism from a protective structure." [GOC:dgh, GOC:isa_complete, ISBN:0198612001]
is_a: GO:0071684 ! organism emergence from protective structure
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0035295
name: tube development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790]
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0035556
name: intracellular signal transduction
namespace: biological_process
alt_id: GO:0007242
alt_id: GO:0007243
alt_id: GO:0023013
alt_id: GO:0023034
def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
synonym: "intracellular protein kinase cascade" NARROW [GOC:signaling]
synonym: "intracellular signal transduction pathway" NARROW []
synonym: "intracellular signaling cascade" RELATED [GOC:signaling]
synonym: "intracellular signaling chain" EXACT [ISBN:3527303782]
synonym: "intracellular signaling pathway" RELATED []
synonym: "protein kinase cascade" NARROW [GOC:signaling]
synonym: "signal transduction via intracellular signaling cascade" RELATED []
synonym: "signal transmission via intracellular cascade" NARROW []
is_a: GO:0007165 ! signal transduction
intersection_of: GO:0007165 ! signal transduction
intersection_of: occurs_in GO:0005622 ! intracellular
relationship: occurs_in GO:0005622 ! intracellular
created_by: rfoulger
creation_date: 2010-05-14T01:14:37Z

[Term]
id: GO:0035637
name: multicellular organismal signaling
namespace: biological_process
def: "The transfer of information occurring at the level of a multicellular organism." [GOC:go_curators]
synonym: "multicellular organismal signalling" EXACT [GOC:bf]
is_a: GO:0023052 ! signaling
is_a: GO:0032501 ! multicellular organismal process
created_by: rfoulger
creation_date: 2011-01-14T10:13:50Z

[Term]
id: GO:0036268
name: swimming
namespace: biological_process
def: "Self-propelled movement of an organism from one location to another through water, often by means of active fin movement." [GOC:cvs, PMID:22459995]
comment: For behavioral aspects of swimming, consider instead annotating to 'swimming behavior ; GO:0036269'.
is_a: GO:0040011 ! locomotion
created_by: rfoulger
creation_date: 2012-07-04T10:12:24Z

[Term]
id: GO:0038023
name: signaling receptor activity
namespace: molecular_function
alt_id: GO:0004872
alt_id: GO:0019041
def: "Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:bf, GOC:signaling]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
synonym: "receptor activity" BROAD []
synonym: "receptor activity involved in signal transduction" EXACT [GOC:bf]
is_a: GO:0060089 ! molecular transducer activity
created_by: rfoulger
creation_date: 2011-08-01T02:45:27Z

[Term]
id: GO:0040007
name: growth
namespace: biological_process
alt_id: GO:0048590
def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma]
comment: See also the biological process term 'cell growth ; GO:0016049'.
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
synonym: "growth pattern" RELATED []
synonym: "non-developmental growth" RELATED [GOC:mah]
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0040008
name: regulation of growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0040007 ! growth
relationship: regulates GO:0040007 ! growth

[Term]
id: GO:0040011
name: locomotion
namespace: biological_process
def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
xref: MIPS_funcat:02.45.11
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0040012
name: regulation of locomotion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0040011 ! locomotion
relationship: regulates GO:0040011 ! locomotion

[Term]
id: GO:0040013
name: negative regulation of locomotion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators]
synonym: "down regulation of locomotion" EXACT []
synonym: "down-regulation of locomotion" EXACT []
synonym: "downregulation of locomotion" EXACT []
synonym: "inhibition of locomotion" NARROW []
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0040011 ! locomotion
relationship: negatively_regulates GO:0040011 ! locomotion

[Term]
id: GO:0040017
name: positive regulation of locomotion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators]
synonym: "activation of locomotion" NARROW []
synonym: "stimulation of locomotion" NARROW []
synonym: "up regulation of locomotion" EXACT []
synonym: "up-regulation of locomotion" EXACT []
synonym: "upregulation of locomotion" EXACT []
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0040011 ! locomotion
relationship: positively_regulates GO:0040011 ! locomotion

[Term]
id: GO:0040019
name: positive regulation of embryonic development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators]
synonym: "activation of embryonic development" NARROW []
synonym: "stimulation of embryonic development" NARROW []
synonym: "up regulation of embryonic development" EXACT []
synonym: "up-regulation of embryonic development" EXACT []
synonym: "upregulation of embryonic development" EXACT []
is_a: GO:0045995 ! regulation of embryonic development
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0009790 ! embryo development
relationship: positively_regulates GO:0009790 ! embryo development

[Term]
id: GO:0042074
name: cell migration involved in gastrulation
namespace: biological_process
def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437]
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0007369 ! gastrulation
relationship: part_of GO:0007369 ! gastrulation

[Term]
id: GO:0042127
name: regulation of cell population proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl]
synonym: "regulation of cell proliferation" RELATED []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0008283 ! cell population proliferation
relationship: regulates GO:0008283 ! cell population proliferation

[Term]
id: GO:0042325
name: regulation of phosphorylation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl]
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0016310 ! phosphorylation
relationship: regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042326
name: negative regulation of phosphorylation
namespace: biological_process
def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl]
synonym: "down regulation of phosphorylation" EXACT []
synonym: "down-regulation of phosphorylation" EXACT []
synonym: "downregulation of phosphorylation" EXACT []
synonym: "inhibition of phosphorylation" NARROW []
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0016310 ! phosphorylation
relationship: negatively_regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042327
name: positive regulation of phosphorylation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl]
synonym: "activation of phosphorylation" NARROW []
synonym: "stimulation of phosphorylation" NARROW []
synonym: "up regulation of phosphorylation" EXACT []
synonym: "up-regulation of phosphorylation" EXACT []
synonym: "upregulation of phosphorylation" EXACT []
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0016310 ! phosphorylation
relationship: positively_regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042391
name: regulation of membrane potential
namespace: biological_process
def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732]
is_a: GO:0065008 ! regulation of biological quality

[Term]
id: GO:0042692
name: muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators]
synonym: "myogenesis" RELATED []
is_a: GO:0030154 ! cell differentiation
relationship: part_of GO:0061061 ! muscle structure development

[Term]
id: GO:0043085
name: positive regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048554
def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]
subset: goslim_chembl
synonym: "activation of enzyme activity" NARROW []
synonym: "activation of metalloenzyme activity" NARROW []
synonym: "positive regulation of enzyme activity" EXACT [GOC:tb]
synonym: "positive regulation of metalloenzyme activity" NARROW []
synonym: "stimulation of enzyme activity" NARROW []
synonym: "stimulation of metalloenzyme activity" NARROW []
synonym: "up regulation of enzyme activity" EXACT []
synonym: "up regulation of metalloenzyme activity" NARROW []
synonym: "up-regulation of enzyme activity" EXACT []
synonym: "up-regulation of metalloenzyme activity" NARROW []
synonym: "upregulation of enzyme activity" EXACT []
synonym: "upregulation of metalloenzyme activity" NARROW []
xref: MIPS_funcat:18.02.01.01
is_a: GO:0044093 ! positive regulation of molecular function
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0003824 ! catalytic activity
relationship: positively_regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0043086
name: negative regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048553
def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]
synonym: "down regulation of enzyme activity" EXACT []
synonym: "down regulation of metalloenzyme activity" NARROW []
synonym: "down-regulation of enzyme activity" EXACT []
synonym: "down-regulation of metalloenzyme activity" EXACT []
synonym: "downregulation of enzyme activity" EXACT []
synonym: "downregulation of metalloenzyme activity" NARROW []
synonym: "inhibition of enzyme activity" NARROW []
synonym: "inhibition of metalloenzyme activity" NARROW []
synonym: "negative regulation of enzyme activity" EXACT [GOC:tb]
synonym: "negative regulation of metalloenzyme activity" NARROW []
is_a: GO:0044092 ! negative regulation of molecular function
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0003824 ! catalytic activity
relationship: negatively_regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0043226
name: organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
xref: NIF_Subcellular:sao1539965131
xref: Wikipedia:Organelle
is_a: GO:0005575 ! cellular_component

[Term]
id: GO:0043227
name: membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators]
synonym: "membrane-enclosed organelle" EXACT []
xref: NIF_Subcellular:sao414196390
is_a: GO:0043226 ! organelle

[Term]
id: GO:0043228
name: non-membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators]
synonym: "non-membrane-enclosed organelle" EXACT []
xref: NIF_Subcellular:sao1456184038
is_a: GO:0043226 ! organelle

[Term]
id: GO:0043229
name: intracellular organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_pir
is_a: GO:0043226 ! organelle
is_a: GO:0044424 ! intracellular part
intersection_of: GO:0043226 ! organelle
intersection_of: part_of GO:0005622 ! intracellular

[Term]
id: GO:0043231
name: intracellular membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_pir
synonym: "intracellular membrane-enclosed organelle" EXACT []
is_a: GO:0043227 ! membrane-bounded organelle
is_a: GO:0043229 ! intracellular organelle

[Term]
id: GO:0043232
name: intracellular non-membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators]
subset: goslim_mouse
subset: goslim_pir
synonym: "intracellular non-membrane-enclosed organelle" EXACT []
is_a: GO:0043228 ! non-membrane-bounded organelle
is_a: GO:0043229 ! intracellular organelle
intersection_of: GO:0043228 ! non-membrane-bounded organelle
intersection_of: part_of GO:0005622 ! intracellular

[Term]
id: GO:0043292
name: contractile fiber
namespace: cellular_component
def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194]
synonym: "contractile fibre" EXACT []
synonym: "muscle fiber" BROAD []
synonym: "muscle fibre" BROAD []
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
is_a: GO:0044444 ! cytoplasmic part
is_a: GO:0099512 ! supramolecular fiber

[Term]
id: GO:0043393
name: regulation of protein binding
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein binding." [GOC:go_curators]
is_a: GO:0051098 ! regulation of binding
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0005515 ! protein binding
relationship: regulates GO:0005515 ! protein binding

[Term]
id: GO:0043549
name: regulation of kinase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf]
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0016301 ! kinase activity
relationship: regulates GO:0016301 ! kinase activity

[Term]
id: GO:0044057
name: regulation of system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl]
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0003008 ! system process
relationship: regulates GO:0003008 ! system process

[Term]
id: GO:0044085
name: cellular component biogenesis
namespace: biological_process
alt_id: GO:0071843
def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah]
subset: goslim_pir
synonym: "cellular component biogenesis at cellular level" EXACT []
is_a: GO:0071840 ! cellular component organization or biogenesis

[Term]
id: GO:0044087
name: regulation of cellular component biogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0044085 ! cellular component biogenesis
relationship: regulates GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0044089
name: positive regulation of cellular component biogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl]
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0044085 ! cellular component biogenesis
relationship: positively_regulates GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0044092
name: negative regulation of molecular function
namespace: biological_process
def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl]
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0003674 ! molecular_function
relationship: negatively_regulates GO:0003674 ! molecular_function
created_by: jane
creation_date: 2009-04-21T04:07:27Z

[Term]
id: GO:0044093
name: positive regulation of molecular function
namespace: biological_process
def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl]
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0003674 ! molecular_function
relationship: positively_regulates GO:0003674 ! molecular_function
created_by: jane
creation_date: 2009-04-21T04:11:06Z

[Term]
id: GO:0044237
name: cellular metabolic process
namespace: biological_process
def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators]
synonym: "cellular metabolism" EXACT []
synonym: "intermediary metabolism" RELATED [GOC:mah]
is_a: GO:0008152 ! metabolic process
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0044422
name: organelle part
namespace: cellular_component
def: "Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0005575 ! cellular_component
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0043226 ! organelle
relationship: part_of GO:0043226 ! organelle

[Term]
id: GO:0044424
name: intracellular part
namespace: cellular_component
def: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0044464 ! cell part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005622 ! intracellular
relationship: part_of GO:0005622 ! intracellular

[Term]
id: GO:0044425
name: membrane part
namespace: cellular_component
def: "Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0005575 ! cellular_component
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0016020 ! membrane
relationship: part_of GO:0016020 ! membrane

[Term]
id: GO:0044428
name: nuclear part
namespace: cellular_component
def: "Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
synonym: "nuclear subcomponent" EXACT [NIF_Subcellular:sao1499850686]
synonym: "nucleus component" EXACT []
xref: NIF_Subcellular:sao1499850686
is_a: GO:0044446 ! intracellular organelle part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005634 ! nucleus
relationship: part_of GO:0005634 ! nucleus

[Term]
id: GO:0044430
name: cytoskeletal part
namespace: cellular_component
def: "Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
synonym: "cytoskeletal element" EXACT [NIF_Subcellular:sao1635329413]
synonym: "cytoskeleton component" EXACT []
xref: NIF_Subcellular:sao1635329413
is_a: GO:0044446 ! intracellular organelle part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005856 ! cytoskeleton
relationship: part_of GO:0005856 ! cytoskeleton

[Term]
id: GO:0044433
name: cytoplasmic vesicle part
namespace: cellular_component
def: "Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0044444 ! cytoplasmic part
is_a: GO:0044446 ! intracellular organelle part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0031410 ! cytoplasmic vesicle
relationship: part_of GO:0031410 ! cytoplasmic vesicle

[Term]
id: GO:0044437
name: vacuolar part
namespace: cellular_component
def: "Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
synonym: "vacuole component" EXACT []
is_a: GO:0044444 ! cytoplasmic part
is_a: GO:0044446 ! intracellular organelle part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005773 ! vacuole
relationship: part_of GO:0005773 ! vacuole

[Term]
id: GO:0044444
name: cytoplasmic part
namespace: cellular_component
def: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
synonym: "cytoplasm component" EXACT []
is_a: GO:0044424 ! intracellular part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0044446
name: intracellular organelle part
namespace: cellular_component
def: "A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0044422 ! organelle part
is_a: GO:0044424 ! intracellular part
relationship: part_of GO:0043229 ! intracellular organelle

[Term]
id: GO:0044449
name: contractile fiber part
namespace: cellular_component
def: "Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
synonym: "contractile fibre component" EXACT []
synonym: "muscle fiber component" BROAD []
synonym: "muscle fibre component" BROAD []
is_a: GO:0044422 ! organelle part
is_a: GO:0044444 ! cytoplasmic part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0043292 ! contractile fiber
relationship: part_of GO:0043292 ! contractile fiber

[Term]
id: GO:0044459
name: plasma membrane part
namespace: cellular_component
def: "Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
is_a: GO:0044425 ! membrane part
is_a: GO:0044464 ! cell part
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005886 ! plasma membrane
relationship: part_of GO:0005886 ! plasma membrane

[Term]
id: GO:0044464
name: cell part
namespace: cellular_component
def: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "cellular subcomponent" EXACT [NIF_Subcellular:sao628508602]
synonym: "protoplast" RELATED [GOC:mah]
xref: NIF_Subcellular:sao628508602
is_a: CARO:0000014 ! cell part
is_a: GO:0005575 ! cellular_component
intersection_of: GO:0005575 ! cellular_component
intersection_of: part_of GO:0005623 ! cell
relationship: part_of GO:0005623 ! cell
property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl

[Term]
id: GO:0045214
name: sarcomere organization
namespace: biological_process
alt_id: GO:0006938
def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf]
synonym: "sarcomere alignment" EXACT []
synonym: "sarcomere organisation" EXACT [GOC:curators]
is_a: GO:0031032 ! actomyosin structure organization
relationship: part_of GO:0030239 ! myofibril assembly

[Term]
id: GO:0045595
name: regulation of cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0030154 ! cell differentiation
relationship: regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045596
name: negative regulation of cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators]
synonym: "down regulation of cell differentiation" EXACT []
synonym: "down-regulation of cell differentiation" EXACT []
synonym: "downregulation of cell differentiation" EXACT []
synonym: "inhibition of cell differentiation" NARROW []
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0030154 ! cell differentiation
relationship: negatively_regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045597
name: positive regulation of cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators]
synonym: "activation of cell differentiation" NARROW []
synonym: "stimulation of cell differentiation" NARROW []
synonym: "up regulation of cell differentiation" EXACT []
synonym: "up-regulation of cell differentiation" EXACT []
synonym: "upregulation of cell differentiation" EXACT []
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0030154 ! cell differentiation
relationship: positively_regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045664
name: regulation of neuron differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
is_a: GO:0050767 ! regulation of neurogenesis
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0030182 ! neuron differentiation
relationship: regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045665
name: negative regulation of neuron differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
synonym: "down regulation of neuron differentiation" EXACT []
synonym: "down-regulation of neuron differentiation" EXACT []
synonym: "downregulation of neuron differentiation" EXACT []
synonym: "inhibition of neuron differentiation" NARROW []
is_a: GO:0045664 ! regulation of neuron differentiation
is_a: GO:0050768 ! negative regulation of neurogenesis
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0030182 ! neuron differentiation
relationship: negatively_regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045666
name: positive regulation of neuron differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
synonym: "activation of neuron differentiation" NARROW []
synonym: "stimulation of neuron differentiation" NARROW []
synonym: "up regulation of neuron differentiation" EXACT []
synonym: "up-regulation of neuron differentiation" EXACT []
synonym: "upregulation of neuron differentiation" EXACT []
is_a: GO:0045664 ! regulation of neuron differentiation
is_a: GO:0050769 ! positive regulation of neurogenesis
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0030182 ! neuron differentiation
relationship: positively_regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045759
name: negative regulation of action potential
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators]
synonym: "down regulation of action potential" EXACT []
synonym: "down-regulation of action potential" EXACT []
synonym: "downregulation of action potential" EXACT []
synonym: "inhibition of action potential" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0001508 ! action potential
relationship: negatively_regulates GO:0001508 ! action potential

[Term]
id: GO:0045760
name: positive regulation of action potential
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators]
synonym: "activation of action potential" NARROW []
synonym: "stimulation of action potential" NARROW []
synonym: "up regulation of action potential" EXACT []
synonym: "up-regulation of action potential" EXACT []
synonym: "upregulation of action potential" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0001508 ! action potential
relationship: positively_regulates GO:0001508 ! action potential

[Term]
id: GO:0045786
name: negative regulation of cell cycle
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of progression through cell cycle" EXACT []
synonym: "down-regulation of progression through cell cycle" EXACT []
synonym: "downregulation of progression through cell cycle" EXACT []
synonym: "inhibition of progression through cell cycle" NARROW []
synonym: "negative regulation of cell cycle progression" EXACT []
synonym: "negative regulation of progression through cell cycle" EXACT []
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007049 ! cell cycle
relationship: negatively_regulates GO:0007049 ! cell cycle

[Term]
id: GO:0045787
name: positive regulation of cell cycle
namespace: biological_process
def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators]
synonym: "activation of progression through cell cycle" NARROW []
synonym: "positive regulation of cell cycle progression" EXACT []
synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of progression through cell cycle" NARROW []
synonym: "up regulation of progression through cell cycle" EXACT []
synonym: "up-regulation of progression through cell cycle" EXACT []
synonym: "upregulation of progression through cell cycle" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007049 ! cell cycle
relationship: positively_regulates GO:0007049 ! cell cycle

[Term]
id: GO:0045839
name: negative regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of mitosis" EXACT []
synonym: "down-regulation of mitosis" EXACT []
synonym: "downregulation of mitosis" EXACT []
synonym: "inhibition of mitosis" NARROW []
synonym: "negative regulation of mitosis" EXACT []
is_a: GO:0007088 ! regulation of mitotic nuclear division
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0045930 ! negative regulation of mitotic cell cycle
is_a: GO:0051784 ! negative regulation of nuclear division
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0140014 ! mitotic nuclear division
relationship: negatively_regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0045840
name: positive regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators]
synonym: "activation of mitosis" NARROW []
synonym: "mitogenic activity" NARROW []
synonym: "positive regulation of mitosis" EXACT []
synonym: "stimulation of mitosis" NARROW []
synonym: "up regulation of mitosis" EXACT []
synonym: "up-regulation of mitosis" EXACT []
synonym: "upregulation of mitosis" EXACT []
is_a: GO:0007088 ! regulation of mitotic nuclear division
is_a: GO:0045931 ! positive regulation of mitotic cell cycle
is_a: GO:0051785 ! positive regulation of nuclear division
is_a: GO:0090068 ! positive regulation of cell cycle process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0140014 ! mitotic nuclear division
relationship: positively_regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0045926
name: negative regulation of growth
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators]
synonym: "down regulation of growth" EXACT []
synonym: "down-regulation of growth" EXACT []
synonym: "downregulation of growth" EXACT []
synonym: "inhibition of growth" NARROW []
is_a: GO:0040008 ! regulation of growth
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0040007 ! growth
relationship: negatively_regulates GO:0040007 ! growth

[Term]
id: GO:0045927
name: positive regulation of growth
namespace: biological_process
def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators]
synonym: "activation of growth" NARROW []
synonym: "stimulation of growth" NARROW []
synonym: "up regulation of growth" EXACT []
synonym: "up-regulation of growth" EXACT []
synonym: "upregulation of growth" EXACT []
is_a: GO:0040008 ! regulation of growth
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0040007 ! growth
relationship: positively_regulates GO:0040007 ! growth

[Term]
id: GO:0045930
name: negative regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of progression through mitotic cell cycle" EXACT []
synonym: "down-regulation of progression through mitotic cell cycle" EXACT []
synonym: "downregulation of progression through mitotic cell cycle" EXACT []
synonym: "inhibition of progression through mitotic cell cycle" NARROW []
synonym: "negative regulation of mitotic cell cycle progression" EXACT []
synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0045786 ! negative regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0000278 ! mitotic cell cycle
relationship: negatively_regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0045931
name: positive regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "activation of progression through mitotic cell cycle" NARROW []
synonym: "positive regulation of mitotic cell cycle progression" EXACT []
synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of progression through mitotic cell cycle" NARROW []
synonym: "up regulation of progression through mitotic cell cycle" EXACT []
synonym: "up-regulation of progression through mitotic cell cycle" EXACT []
synonym: "upregulation of progression through mitotic cell cycle" EXACT []
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0045787 ! positive regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0000278 ! mitotic cell cycle
relationship: positively_regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0045936
name: negative regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "down regulation of phosphate metabolic process" EXACT []
synonym: "down-regulation of phosphate metabolic process" EXACT []
synonym: "downregulation of phosphate metabolic process" EXACT []
synonym: "inhibition of phosphate metabolic process" NARROW []
synonym: "negative regulation of phosphate metabolism" EXACT []
is_a: GO:0010563 ! negative regulation of phosphorus metabolic process
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0045937
name: positive regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "activation of phosphate metabolic process" NARROW []
synonym: "positive regulation of phosphate metabolism" EXACT []
synonym: "stimulation of phosphate metabolic process" NARROW []
synonym: "up regulation of phosphate metabolic process" EXACT []
synonym: "up-regulation of phosphate metabolic process" EXACT []
synonym: "upregulation of phosphate metabolic process" EXACT []
is_a: GO:0010562 ! positive regulation of phosphorus metabolic process
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0045992
name: negative regulation of embryonic development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators]
synonym: "down regulation of embryonic development" EXACT []
synonym: "down-regulation of embryonic development" EXACT []
synonym: "downregulation of embryonic development" EXACT []
synonym: "inhibition of embryonic development" NARROW []
is_a: GO:0045995 ! regulation of embryonic development
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0009790 ! embryo development
relationship: negatively_regulates GO:0009790 ! embryo development

[Term]
id: GO:0045995
name: regulation of embryonic development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0009790 ! embryo development
relationship: regulates GO:0009790 ! embryo development

[Term]
id: GO:0048018
name: receptor ligand activity
namespace: molecular_function
alt_id: GO:0071884
def: "The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands)." [GOC:kv, GOC:molecular_function_refactoring, GOC:pdt]
comment: Definition discussed in https://github.com/geneontology/go-ontology/issues/14220
subset: goslim_chembl
synonym: "receptor agonist activity" BROAD [GOC:molecular_function_refactoring]
synonym: "signaling molecule" EXACT []
synonym: "signaling receptor ligand activity" EXACT []
synonym: "vitamin D receptor activator activity" NARROW []
is_a: GO:0005102 ! signaling receptor binding
is_a: GO:0030546 ! signaling receptor activator activity
relationship: part_of GO:0007165 ! signal transduction
created_by: midori
creation_date: 2010-09-13T04:51:59Z

[Term]
id: GO:0048285
name: organelle fission
namespace: biological_process
def: "The creation of two or more organelles by division of one organelle." [GOC:jid]
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization

[Term]
id: GO:0048332
name: mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators]
is_a: GO:0048729 ! tissue morphogenesis
relationship: part_of GO:0007498 ! mesoderm development

[Term]
id: GO:0048468
name: cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:go_curators]
subset: goslim_candida
synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb]
is_a: GO:0048856 ! anatomical structure development
is_a: GO:0048869 ! cellular developmental process
relationship: part_of GO:0030154 ! cell differentiation

[Term]
id: GO:0048518
name: positive regulation of biological process
namespace: biological_process
alt_id: GO:0043119
def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "activation of biological process" NARROW []
synonym: "positive regulation of physiological process" EXACT []
synonym: "stimulation of biological process" NARROW []
synonym: "up regulation of biological process" EXACT []
synonym: "up-regulation of biological process" EXACT []
synonym: "upregulation of biological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0008150 ! biological_process
relationship: positively_regulates GO:0008150 ! biological_process

[Term]
id: GO:0048519
name: negative regulation of biological process
namespace: biological_process
alt_id: GO:0043118
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "down regulation of biological process" EXACT []
synonym: "down-regulation of biological process" EXACT []
synonym: "downregulation of biological process" EXACT []
synonym: "inhibition of biological process" NARROW []
synonym: "negative regulation of physiological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0008150 ! biological_process
relationship: negatively_regulates GO:0008150 ! biological_process

[Term]
id: GO:0048520
name: positive regulation of behavior
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr]
synonym: "activation of behavior" NARROW []
synonym: "stimulation of behavior" NARROW []
synonym: "up regulation of behavior" EXACT []
synonym: "up-regulation of behavior" EXACT []
synonym: "upregulation of behavior" EXACT []
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:0050795 ! regulation of behavior
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007610 ! behavior
relationship: positively_regulates GO:0007610 ! behavior

[Term]
id: GO:0048521
name: negative regulation of behavior
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr]
synonym: "down regulation of behavior" EXACT []
synonym: "down-regulation of behavior" EXACT []
synonym: "downregulation of behavior" EXACT []
synonym: "inhibition of behavior" NARROW []
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:0050795 ! regulation of behavior
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007610 ! behavior
relationship: negatively_regulates GO:0007610 ! behavior

[Term]
id: GO:0048522
name: positive regulation of cellular process
namespace: biological_process
alt_id: GO:0051242
def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid]
synonym: "activation of cellular process" NARROW []
synonym: "positive regulation of cellular physiological process" EXACT []
synonym: "stimulation of cellular process" NARROW []
synonym: "up regulation of cellular process" EXACT []
synonym: "up-regulation of cellular process" EXACT []
synonym: "upregulation of cellular process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0009987 ! cellular process
relationship: positively_regulates GO:0009987 ! cellular process

[Term]
id: GO:0048523
name: negative regulation of cellular process
namespace: biological_process
alt_id: GO:0051243
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid]
synonym: "down regulation of cellular process" EXACT []
synonym: "down-regulation of cellular process" EXACT []
synonym: "downregulation of cellular process" EXACT []
synonym: "inhibition of cellular process" NARROW []
synonym: "negative regulation of cellular physiological process" EXACT []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0009987 ! cellular process
relationship: negatively_regulates GO:0009987 ! cellular process

[Term]
id: GO:0048583
name: regulation of response to stimulus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0050896 ! response to stimulus
relationship: regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048584
name: positive regulation of response to stimulus
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "activation of response to stimulus" NARROW []
synonym: "stimulation of response to stimulus" NARROW []
synonym: "up regulation of response to stimulus" EXACT []
synonym: "up-regulation of response to stimulus" EXACT []
synonym: "upregulation of response to stimulus" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0050896 ! response to stimulus
relationship: positively_regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048585
name: negative regulation of response to stimulus
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of response to stimulus" EXACT []
synonym: "down-regulation of response to stimulus" EXACT []
synonym: "downregulation of response to stimulus" EXACT []
synonym: "inhibition of response to stimulus" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0050896 ! response to stimulus
relationship: negatively_regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048589
name: developmental growth
namespace: biological_process
def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators]
is_a: GO:0032502 ! developmental process
is_a: GO:0040007 ! growth

[Term]
id: GO:0048598
name: embryonic morphogenesis
namespace: biological_process
alt_id: GO:0048828
def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu]
synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009790 ! embryo development

[Term]
id: GO:0048608
name: reproductive structure development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid]
xref: MIPS_funcat:45.03.15
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0061458 ! reproductive system development

[Term]
id: GO:0048609
name: multicellular organismal reproductive process
namespace: biological_process
def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb]
synonym: "organismal reproductive process" BROAD [GOC:curators]
synonym: "reproductive process in a multicellular organism" EXACT [GOC:curators]
is_a: GO:0022414 ! reproductive process
relationship: part_of GO:0032504 ! multicellular organism reproduction

[Term]
id: GO:0048638
name: regulation of developmental growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators]
is_a: GO:0040008 ! regulation of growth
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0048589 ! developmental growth
relationship: regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048639
name: positive regulation of developmental growth
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators]
synonym: "activation of developmental growth" NARROW []
synonym: "stimulation of developmental growth" NARROW []
synonym: "up regulation of developmental growth" EXACT []
synonym: "up-regulation of developmental growth" EXACT []
synonym: "upregulation of developmental growth" EXACT []
is_a: GO:0045927 ! positive regulation of growth
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0048589 ! developmental growth
relationship: positively_regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048640
name: negative regulation of developmental growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators]
synonym: "down regulation of developmental growth" EXACT []
synonym: "down-regulation of developmental growth" EXACT []
synonym: "downregulation of developmental growth" EXACT []
synonym: "inhibition of developmental growth" NARROW []
is_a: GO:0045926 ! negative regulation of growth
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0048589 ! developmental growth
relationship: negatively_regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048646
name: anatomical structure formation involved in morphogenesis
namespace: biological_process
def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb]
comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.
subset: goslim_chembl
subset: goslim_generic
synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0032502 ! developmental process
relationship: part_of GO:0009653 ! anatomical structure morphogenesis

[Term]
id: GO:0048666
name: neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph]
is_a: GO:0048468 ! cell development
relationship: part_of GO:0030182 ! neuron differentiation

[Term]
id: GO:0048678
name: response to axon injury
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]
is_a: GO:0009611 ! response to wounding

[Term]
id: GO:0048679
name: regulation of axon regeneration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]
is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0070570 ! regulation of neuron projection regeneration
is_a: GO:1903034 ! regulation of response to wounding
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0031103 ! axon regeneration
relationship: regulates GO:0031103 ! axon regeneration

[Term]
id: GO:0048680
name: positive regulation of axon regeneration
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]
synonym: "activation of axon regeneration" NARROW []
synonym: "stimulation of axon regeneration" NARROW []
synonym: "up regulation of axon regeneration" EXACT []
synonym: "up-regulation of axon regeneration" EXACT []
synonym: "upregulation of axon regeneration" EXACT []
is_a: GO:0032103 ! positive regulation of response to external stimulus
is_a: GO:0048679 ! regulation of axon regeneration
is_a: GO:0070572 ! positive regulation of neuron projection regeneration
is_a: GO:1903036 ! positive regulation of response to wounding
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0031103 ! axon regeneration
relationship: positively_regulates GO:0031103 ! axon regeneration

[Term]
id: GO:0048681
name: negative regulation of axon regeneration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]
synonym: "down regulation of axon regeneration" EXACT []
synonym: "down-regulation of axon regeneration" EXACT []
synonym: "downregulation of axon regeneration" EXACT []
synonym: "inhibition of axon regeneration" NARROW []
is_a: GO:0032102 ! negative regulation of response to external stimulus
is_a: GO:0048679 ! regulation of axon regeneration
is_a: GO:0070571 ! negative regulation of neuron projection regeneration
is_a: GO:1903035 ! negative regulation of response to wounding
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0031103 ! axon regeneration
relationship: negatively_regulates GO:0031103 ! axon regeneration

[Term]
id: GO:0048699
name: generation of neurons
namespace: biological_process
def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln]
synonym: "neuron generation" EXACT [GOC:curators]
xref: MIPS_funcat:41.05.13
is_a: GO:0022008 ! neurogenesis

[Term]
id: GO:0048729
name: tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid]
is_a: GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009888 ! tissue development

[Term]
id: GO:0048731
name: system development
namespace: biological_process
def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid]
subset: goslim_mouse
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0048747
name: muscle fiber development
namespace: biological_process
def: "The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle]
synonym: "muscle fibre development" EXACT []
synonym: "myofiber development" EXACT []
synonym: "myofibre development" EXACT []
is_a: GO:0055002 ! striated muscle cell development

[Term]
id: GO:0048856
name: anatomical structure development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021, GOC:mtg_15jun06]
comment: This term was added by GO_REF:0000021.
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
synonym: "development of an anatomical structure" EXACT []
is_a: GO:0032502 ! developmental process

[Term]
id: GO:0048869
name: cellular developmental process
namespace: biological_process
def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete]
is_a: GO:0009987 ! cellular process
is_a: GO:0032502 ! developmental process

[Term]
id: GO:0048870
name: cell motility
namespace: biological_process
def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg]
subset: goslim_chembl
subset: goslim_generic
synonym: "cell locomotion" EXACT []
synonym: "cell movement" RELATED []
synonym: "movement of a cell" EXACT []
is_a: GO:0006928 ! movement of cell or subcellular component
is_a: GO:0040011 ! locomotion
relationship: part_of GO:0051674 ! localization of cell

[Term]
id: GO:0050767
name: regulation of neurogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai]
is_a: GO:0051960 ! regulation of nervous system development
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0022008 ! neurogenesis
relationship: part_of GO:0048699 ! generation of neurons
relationship: regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050768
name: negative regulation of neurogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai]
synonym: "down regulation of neurogenesis" EXACT []
synonym: "down-regulation of neurogenesis" EXACT []
synonym: "downregulation of neurogenesis" EXACT []
synonym: "inhibition of neurogenesis" NARROW []
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0050767 ! regulation of neurogenesis
is_a: GO:0051961 ! negative regulation of nervous system development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0022008 ! neurogenesis
relationship: negatively_regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050769
name: positive regulation of neurogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai]
synonym: "activation of neurogenesis" NARROW []
synonym: "stimulation of neurogenesis" NARROW []
synonym: "up regulation of neurogenesis" EXACT []
synonym: "up-regulation of neurogenesis" EXACT []
synonym: "upregulation of neurogenesis" EXACT []
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0050767 ! regulation of neurogenesis
is_a: GO:0051962 ! positive regulation of nervous system development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0022008 ! neurogenesis
relationship: positively_regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050789
name: regulation of biological process
namespace: biological_process
alt_id: GO:0050791
def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators]
subset: gocheck_do_not_annotate
subset: goslim_agr
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_pir
synonym: "regulation of physiological process" EXACT []
is_a: GO:0065007 ! biological regulation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0008150 ! biological_process
relationship: regulates GO:0008150 ! biological_process

[Term]
id: GO:0050790
name: regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048552
def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw]
subset: goslim_chembl
synonym: "regulation of enzyme activity" EXACT []
synonym: "regulation of metalloenzyme activity" NARROW []
xref: MIPS_funcat:18.02.01
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0003824 ! catalytic activity
relationship: regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0050793
name: regulation of developmental process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0032502 ! developmental process
relationship: regulates GO:0032502 ! developmental process

[Term]
id: GO:0050794
name: regulation of cellular process
namespace: biological_process
alt_id: GO:0051244
def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators]
synonym: "regulation of cellular physiological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0009987 ! cellular process
relationship: regulates GO:0009987 ! cellular process

[Term]
id: GO:0050795
name: regulation of behavior
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr]
synonym: "regulation of behaviour" EXACT []
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007610 ! behavior
relationship: regulates GO:0007610 ! behavior

[Term]
id: GO:0050804
name: modulation of chemical synaptic transmission
namespace: biological_process
def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.  Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai]
subset: goslim_synapse
synonym: "modulation of synaptic transmission" BROAD []
synonym: "regulation of chemical synaptic transmission" EXACT []
synonym: "regulation of synaptic transmission" EXACT []
is_a: GO:0099177 ! regulation of trans-synaptic signaling
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
relationship: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050805
name: negative regulation of synaptic transmission
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai]
synonym: "down regulation of synaptic transmission" EXACT []
synonym: "down-regulation of synaptic transmission" EXACT []
synonym: "downregulation of synaptic transmission" EXACT []
synonym: "inhibition of synaptic transmission" NARROW []
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007268 ! chemical synaptic transmission
relationship: negatively_regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050806
name: positive regulation of synaptic transmission
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai]
synonym: "activation of synaptic transmission" NARROW []
synonym: "stimulation of synaptic transmission" NARROW []
synonym: "up regulation of synaptic transmission" EXACT []
synonym: "up-regulation of synaptic transmission" EXACT []
synonym: "upregulation of synaptic transmission" EXACT []
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007268 ! chemical synaptic transmission
relationship: positively_regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050877
name: nervous system process
namespace: biological_process
def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio]
comment: Discussion of class label and synonyms: https://github.com/geneontology/go-ontology/issues/13824
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_pir
synonym: "neurological system process" EXACT []
synonym: "neurophysiological process" EXACT []
synonym: "pan-neural process" RELATED []
xref: MIPS_funcat:36.25.03
is_a: GO:0003008 ! system process

[Term]
id: GO:0050896
name: response to stimulus
namespace: biological_process
alt_id: GO:0051869
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
synonym: "physiological response to stimulus" EXACT []
xref: MIPS_funcat:34.11
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0051093
name: negative regulation of developmental process
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai]
synonym: "down regulation of developmental process" EXACT []
synonym: "down-regulation of developmental process" EXACT []
synonym: "downregulation of developmental process" EXACT []
synonym: "inhibition of developmental process" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0032502 ! developmental process
relationship: negatively_regulates GO:0032502 ! developmental process

[Term]
id: GO:0051094
name: positive regulation of developmental process
namespace: biological_process
def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai]
synonym: "activation of developmental process" NARROW []
synonym: "stimulation of developmental process" NARROW []
synonym: "up regulation of developmental process" EXACT []
synonym: "up-regulation of developmental process" EXACT []
synonym: "upregulation of developmental process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0032502 ! developmental process
relationship: positively_regulates GO:0032502 ! developmental process

[Term]
id: GO:0051098
name: regulation of binding
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai]
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0005488 ! binding
relationship: regulates GO:0005488 ! binding

[Term]
id: GO:0051099
name: positive regulation of binding
namespace: biological_process
def: "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai]
synonym: "activation of binding" NARROW []
synonym: "stimulation of binding" NARROW []
synonym: "up regulation of binding" EXACT []
synonym: "up-regulation of binding" EXACT []
synonym: "upregulation of binding" EXACT []
is_a: GO:0044093 ! positive regulation of molecular function
is_a: GO:0051098 ! regulation of binding
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0005488 ! binding
relationship: positively_regulates GO:0005488 ! binding

[Term]
id: GO:0051100
name: negative regulation of binding
namespace: biological_process
def: "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai]
synonym: "down regulation of binding" EXACT []
synonym: "down-regulation of binding" EXACT []
synonym: "downregulation of binding" EXACT []
synonym: "inhibition of binding" NARROW []
is_a: GO:0044092 ! negative regulation of molecular function
is_a: GO:0051098 ! regulation of binding
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0005488 ! binding
relationship: negatively_regulates GO:0005488 ! binding

[Term]
id: GO:0051128
name: regulation of cellular component organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "regulation of cell organisation" RELATED [GOC:mah]
synonym: "regulation of cell organization" RELATED [GOC:mah]
synonym: "regulation of cellular component organisation" EXACT [GOC:curators]
synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0016043 ! cellular component organization
relationship: regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051129
name: negative regulation of cellular component organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "down regulation of cell organization" EXACT []
synonym: "down-regulation of cell organization" EXACT []
synonym: "downregulation of cell organization" EXACT []
synonym: "inhibition of cell organization" NARROW []
synonym: "negative regulation of cell organisation" RELATED [GOC:mah]
synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0016043 ! cellular component organization
relationship: negatively_regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051130
name: positive regulation of cellular component organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "activation of cell organization" NARROW []
synonym: "positive regulation of cell organisation" EXACT []
synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cell organization" NARROW []
synonym: "up regulation of cell organization" EXACT []
synonym: "up-regulation of cell organization" EXACT []
synonym: "upregulation of cell organization" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0016043 ! cellular component organization
relationship: positively_regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051146
name: striated muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai]
synonym: "voluntary muscle cell differentiation" NARROW []
is_a: GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051147
name: regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0042692 ! muscle cell differentiation
relationship: regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051148
name: negative regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
synonym: "down regulation of muscle cell differentiation" EXACT []
synonym: "down-regulation of muscle cell differentiation" EXACT []
synonym: "downregulation of muscle cell differentiation" EXACT []
synonym: "inhibition of muscle cell differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0042692 ! muscle cell differentiation
relationship: negatively_regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051149
name: positive regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
synonym: "activation of muscle cell differentiation" NARROW []
synonym: "stimulation of muscle cell differentiation" NARROW []
synonym: "up regulation of muscle cell differentiation" EXACT []
synonym: "up-regulation of muscle cell differentiation" EXACT []
synonym: "upregulation of muscle cell differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0042692 ! muscle cell differentiation
relationship: positively_regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051153
name: regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0051146 ! striated muscle cell differentiation
relationship: regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051154
name: negative regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
synonym: "down regulation of striated muscle cell differentiation" EXACT []
synonym: "down-regulation of striated muscle cell differentiation" EXACT []
synonym: "downregulation of striated muscle cell differentiation" EXACT []
synonym: "inhibition of striated muscle cell differentiation" NARROW []
is_a: GO:0051148 ! negative regulation of muscle cell differentiation
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0051146 ! striated muscle cell differentiation
relationship: negatively_regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051155
name: positive regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
synonym: "activation of striated muscle cell differentiation" NARROW []
synonym: "stimulation of striated muscle cell differentiation" NARROW []
synonym: "up regulation of striated muscle cell differentiation" EXACT []
synonym: "up-regulation of striated muscle cell differentiation" EXACT []
synonym: "upregulation of striated muscle cell differentiation" EXACT []
is_a: GO:0051149 ! positive regulation of muscle cell differentiation
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0051146 ! striated muscle cell differentiation
relationship: positively_regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051174
name: regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai]
synonym: "regulation of phosphorus metabolism" EXACT []
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0006793 ! phosphorus metabolic process
relationship: regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0051179
name: localization
namespace: biological_process
alt_id: GO:1902578
def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos]
subset: goslim_pir
synonym: "establishment and maintenance of cellular component location" NARROW []
synonym: "establishment and maintenance of localization" EXACT []
synonym: "establishment and maintenance of position" EXACT []
synonym: "establishment and maintenance of substance location" NARROW []
synonym: "establishment and maintenance of substrate location" NARROW []
synonym: "localisation" EXACT [GOC:mah]
synonym: "single organism localization" RELATED [GOC:TermGenie]
synonym: "single-organism localization" RELATED []
is_a: GO:0008150 ! biological_process
created_by: jl
creation_date: 2013-12-18T13:51:04Z

[Term]
id: GO:0051239
name: regulation of multicellular organismal process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0032501 ! multicellular organismal process
relationship: regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051240
name: positive regulation of multicellular organismal process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai]
synonym: "activation of multicellular organismal process" NARROW []
synonym: "stimulation of multicellular organismal process" NARROW []
synonym: "up regulation of multicellular organismal process" EXACT []
synonym: "up-regulation of multicellular organismal process" EXACT []
synonym: "upregulation of multicellular organismal process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0032501 ! multicellular organismal process
relationship: positively_regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051241
name: negative regulation of multicellular organismal process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai]
synonym: "down regulation of multicellular organismal process" EXACT []
synonym: "down-regulation of multicellular organismal process" EXACT []
synonym: "downregulation of multicellular organismal process" EXACT []
synonym: "inhibition of multicellular organismal process" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0032501 ! multicellular organismal process
relationship: negatively_regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051270
name: regulation of cellular component movement
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl]
synonym: "regulation of cell movement" RELATED []
synonym: "regulation of cellular component motion" EXACT [GOC:mah]
is_a: GO:0032879 ! regulation of localization
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0006928 ! movement of cell or subcellular component
relationship: regulates GO:0006928 ! movement of cell or subcellular component

[Term]
id: GO:0051271
name: negative regulation of cellular component movement
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl]
synonym: "down regulation of cell motility" EXACT []
synonym: "down-regulation of cell motility" EXACT []
synonym: "downregulation of cell motility" EXACT []
synonym: "inhibition of cell motility" NARROW []
synonym: "negative regulation of cell movement" RELATED []
synonym: "negative regulation of cellular component motion" EXACT [GOC:mah]
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051270 ! regulation of cellular component movement
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0006928 ! movement of cell or subcellular component
relationship: negatively_regulates GO:0006928 ! movement of cell or subcellular component

[Term]
id: GO:0051272
name: positive regulation of cellular component movement
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl]
synonym: "activation of cell motility" NARROW []
synonym: "positive regulation of cell movement" RELATED []
synonym: "positive regulation of cellular component motion" EXACT [GOC:mah]
synonym: "stimulation of cell motility" NARROW []
synonym: "up regulation of cell motility" EXACT []
synonym: "up-regulation of cell motility" EXACT []
synonym: "upregulation of cell motility" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051270 ! regulation of cellular component movement
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0006928 ! movement of cell or subcellular component
relationship: positively_regulates GO:0006928 ! movement of cell or subcellular component

[Term]
id: GO:0051301
name: cell division
namespace: biological_process
def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr]
comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
xref: Wikipedia:Cell_division
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0051302
name: regulation of cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0051301 ! cell division
relationship: regulates GO:0051301 ! cell division

[Term]
id: GO:0051338
name: regulation of transferase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [EC:2.-.-.-, GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_manually_annotate
synonym: "transferase regulator" EXACT []
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0016740 ! transferase activity
relationship: regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051347
name: positive regulation of transferase activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_manually_annotate
synonym: "activation of transferase activity" NARROW []
synonym: "stimulation of transferase activity" NARROW []
synonym: "transferase activator" EXACT []
synonym: "up regulation of transferase activity" EXACT []
synonym: "up-regulation of transferase activity" EXACT []
synonym: "upregulation of transferase activity" EXACT []
is_a: GO:0043085 ! positive regulation of catalytic activity
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0016740 ! transferase activity
relationship: positively_regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051348
name: negative regulation of transferase activity
namespace: biological_process
def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of transferase activity" EXACT []
synonym: "down-regulation of transferase activity" EXACT []
synonym: "downregulation of transferase activity" EXACT []
synonym: "inhibition of transferase activity" NARROW []
synonym: "transferase inhibitor" EXACT []
is_a: GO:0043086 ! negative regulation of catalytic activity
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0016740 ! transferase activity
relationship: negatively_regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051493
name: regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007010 ! cytoskeleton organization
relationship: regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051494
name: negative regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "down regulation of cytoskeleton organization" EXACT []
synonym: "down-regulation of cytoskeleton organization" EXACT []
synonym: "downregulation of cytoskeleton organization" EXACT []
synonym: "inhibition of cytoskeleton organization" NARROW []
synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007010 ! cytoskeleton organization
relationship: negatively_regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051495
name: positive regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "activation of cytoskeleton organization" NARROW []
synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cytoskeleton organization" NARROW []
synonym: "up regulation of cytoskeleton organization" EXACT []
synonym: "up-regulation of cytoskeleton organization" EXACT []
synonym: "upregulation of cytoskeleton organization" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007010 ! cytoskeleton organization
relationship: positively_regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051641
name: cellular localization
namespace: biological_process
alt_id: GO:1902580
def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw]
subset: goslim_pir
synonym: "cellular localisation" EXACT [GOC:mah]
synonym: "establishment and maintenance of cellular localization" EXACT []
synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT []
synonym: "intracellular localization" NARROW []
synonym: "localization within cell" NARROW []
synonym: "single organism cellular localization" EXACT [GOC:TermGenie]
synonym: "single-organism cellular localization" RELATED []
is_a: GO:0051179 ! localization
created_by: jl
creation_date: 2013-12-18T14:04:32Z

[Term]
id: GO:0051668
name: localization within membrane
namespace: biological_process
def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai]
synonym: "establishment and maintenance of localization in membrane" EXACT []
synonym: "establishment and maintenance of position in membrane" EXACT []
synonym: "localisation within membrane" EXACT [GOC:mah]
synonym: "localization to membrane" EXACT []
synonym: "positioning within membrane" NARROW []
is_a: GO:0051641 ! cellular localization
intersection_of: GO:0051179 ! localization
intersection_of: occurs_in GO:0016020 ! membrane
relationship: occurs_in GO:0016020 ! membrane

[Term]
id: GO:0051674
name: localization of cell
namespace: biological_process
def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai]
synonym: "cell localization" EXACT []
synonym: "establishment and maintenance of cell localization" EXACT []
synonym: "establishment and maintenance of localization of cell" EXACT []
synonym: "localisation of cell" EXACT [GOC:mah]
is_a: GO:0051179 ! localization

[Term]
id: GO:0051716
name: cellular response to stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0009987 ! cellular process
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0051726
name: regulation of cell cycle
namespace: biological_process
alt_id: GO:0000074
def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_yeast
synonym: "cell cycle modulation" EXACT []
synonym: "cell cycle regulation" EXACT []
synonym: "cell cycle regulator" RELATED []
synonym: "control of cell cycle progression" EXACT []
synonym: "modulation of cell cycle progression" EXACT []
synonym: "regulation of cell cycle progression" EXACT []
synonym: "regulation of progression through cell cycle" EXACT []
synonym: "tumor suppressor" RELATED []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007049 ! cell cycle
relationship: regulates GO:0007049 ! cell cycle

[Term]
id: GO:0051781
name: positive regulation of cell division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai]
synonym: "activation of cell division" NARROW []
synonym: "stimulation of cell division" NARROW []
synonym: "up regulation of cell division" EXACT []
synonym: "up-regulation of cell division" EXACT []
synonym: "upregulation of cell division" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0051301 ! cell division
relationship: positively_regulates GO:0051301 ! cell division

[Term]
id: GO:0051782
name: negative regulation of cell division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai]
synonym: "down regulation of cell division" EXACT []
synonym: "down-regulation of cell division" EXACT []
synonym: "downregulation of cell division" EXACT []
synonym: "inhibition of cell division" NARROW []
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0051301 ! cell division
relationship: negatively_regulates GO:0051301 ! cell division

[Term]
id: GO:0051783
name: regulation of nuclear division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0000280 ! nuclear division
relationship: regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051784
name: negative regulation of nuclear division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
synonym: "down regulation of nuclear division" EXACT []
synonym: "down-regulation of nuclear division" EXACT []
synonym: "downregulation of nuclear division" EXACT []
synonym: "inhibition of nuclear division" NARROW []
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0000280 ! nuclear division
relationship: negatively_regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051785
name: positive regulation of nuclear division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
synonym: "activation of nuclear division" NARROW []
synonym: "stimulation of nuclear division" NARROW []
synonym: "up regulation of nuclear division" EXACT []
synonym: "up-regulation of nuclear division" EXACT []
synonym: "upregulation of nuclear division" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0000280 ! nuclear division
relationship: positively_regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051960
name: regulation of nervous system development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007399 ! nervous system development
relationship: regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051961
name: negative regulation of nervous system development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
synonym: "down regulation of nervous system development" EXACT []
synonym: "down-regulation of nervous system development" EXACT []
synonym: "downregulation of nervous system development" EXACT []
synonym: "inhibition of nervous system development" NARROW []
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0051960 ! regulation of nervous system development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007399 ! nervous system development
relationship: negatively_regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051962
name: positive regulation of nervous system development
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
synonym: "activation of nervous system development" NARROW []
synonym: "stimulation of nervous system development" NARROW []
synonym: "up regulation of nervous system development" EXACT []
synonym: "up-regulation of nervous system development" EXACT []
synonym: "upregulation of nervous system development" EXACT []
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0051960 ! regulation of nervous system development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007399 ! nervous system development
relationship: positively_regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051969
name: regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0031644 ! regulation of neurological system process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0019226 ! transmission of nerve impulse
relationship: regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0051970
name: negative regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "down regulation of transmission of nerve impulse" EXACT []
synonym: "down-regulation of transmission of nerve impulse" EXACT []
synonym: "downregulation of transmission of nerve impulse" EXACT []
synonym: "inhibition of transmission of nerve impulse" NARROW []
synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph]
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0031645 ! negative regulation of neurological system process
is_a: GO:0051969 ! regulation of transmission of nerve impulse
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0019226 ! transmission of nerve impulse
relationship: negatively_regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0051971
name: positive regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "activation of transmission of nerve impulse" NARROW []
synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph]
synonym: "stimulation of transmission of nerve impulse" NARROW []
synonym: "up regulation of transmission of nerve impulse" EXACT []
synonym: "up-regulation of transmission of nerve impulse" EXACT []
synonym: "upregulation of transmission of nerve impulse" EXACT []
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0031646 ! positive regulation of neurological system process
is_a: GO:0051969 ! regulation of transmission of nerve impulse
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0019226 ! transmission of nerve impulse
relationship: positively_regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0055001
name: muscle cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol]
is_a: GO:0048468 ! cell development
relationship: part_of GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0055002
name: striated muscle cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol]
is_a: GO:0055001 ! muscle cell development
relationship: part_of GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0060066
name: oviduct development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct]
synonym: "fallopian tube development" NARROW [GOC:bf]
synonym: "Mullerian tract development" RELATED []
is_a: GO:0035295 ! tube development
is_a: GO:0048608 ! reproductive structure development

[Term]
id: GO:0060089
name: molecular transducer activity
namespace: molecular_function
def: "A compound molecular function in which an effector function is controlled by one or more regulatory components." [GOC:dos, GOC:pdt]
subset: gocheck_do_not_manually_annotate
subset: goslim_pir
is_a: GO:0003674 ! molecular_function

[Term]
id: GO:0060284
name: regulation of cell development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0048468 ! cell development
relationship: regulates GO:0048468 ! cell development

[Term]
id: GO:0060297
name: regulation of sarcomere organization
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
is_a: GO:0060284 ! regulation of cell development
is_a: GO:0110020 ! regulation of actomyosin structure organization
is_a: GO:1902115 ! regulation of organelle assembly
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0045214 ! sarcomere organization
relationship: regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060298
name: positive regulation of sarcomere organization
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
is_a: GO:0051495 ! positive regulation of cytoskeleton organization
is_a: GO:0060297 ! regulation of sarcomere organization
is_a: GO:1902117 ! positive regulation of organelle assembly
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0045214 ! sarcomere organization
relationship: positively_regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060299
name: negative regulation of sarcomere organization
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
is_a: GO:0051494 ! negative regulation of cytoskeleton organization
is_a: GO:0060297 ! regulation of sarcomere organization
is_a: GO:1902116 ! negative regulation of organelle assembly
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0045214 ! sarcomere organization
relationship: negatively_regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060341
name: regulation of cellular localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb]
synonym: "regulation of cellular localisation" EXACT [GOC:mah]
is_a: GO:0032879 ! regulation of localization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0051641 ! cellular localization
relationship: regulates GO:0051641 ! cellular localization

[Term]
id: GO:0060560
name: developmental growth involved in morphogenesis
namespace: biological_process
def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph]
synonym: "differential growth" EXACT [GOC:dph]
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009653 ! anatomical structure morphogenesis
created_by: dph
creation_date: 2009-04-28T08:42:53Z

[Term]
id: GO:0060972
name: left/right pattern formation
namespace: biological_process
def: "The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:mtg_heart]
is_a: GO:0003002 ! regionalization
created_by: dph
creation_date: 2009-10-06T10:25:58Z

[Term]
id: GO:0061024
name: membrane organization
namespace: biological_process
alt_id: GO:0016044
alt_id: GO:0044802
def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
synonym: "cellular membrane organisation" EXACT [GOC:curators]
synonym: "cellular membrane organization" EXACT []
synonym: "membrane organisation" EXACT [GOC:mah]
synonym: "membrane organization and biogenesis" RELATED [GOC:mah]
synonym: "single-organism membrane organization" RELATED []
is_a: GO:0016043 ! cellular component organization
created_by: janelomax
creation_date: 2010-02-08T02:43:11Z

[Term]
id: GO:0061061
name: muscle structure development
namespace: biological_process
def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
created_by: dph
creation_date: 2010-03-09T08:55:14Z

[Term]
id: GO:0061351
name: neural precursor cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf]
is_a: GO:0008283 ! cell population proliferation
created_by: dph
creation_date: 2010-10-01T11:06:04Z

[Term]
id: GO:0061458
name: reproductive system development
namespace: biological_process
def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph]
is_a: GO:0048731 ! system development
created_by: dph
creation_date: 2012-08-22T17:47:53Z

[Term]
id: GO:0061564
name: axon development
namespace: biological_process
def: "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." [GOC:dph, GOC:pg, GOC:pr]
is_a: GO:0031175 ! neuron projection development
created_by: dph
creation_date: 2013-07-18T14:43:01Z

[Term]
id: GO:0061640
name: cytoskeleton-dependent cytokinesis
namespace: biological_process
def: "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." [GOC:dph]
is_a: GO:0000910 ! cytokinesis
created_by: dph
creation_date: 2014-08-22T14:21:35Z

[Term]
id: GO:0065007
name: biological regulation
namespace: biological_process
def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "regulation" BROAD []
is_a: GO:0008150 ! biological_process

[Term]
id: GO:0065008
name: regulation of biological quality
namespace: biological_process
def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
subset: goslim_pir
synonym: "regulation of biological attribute" EXACT []
synonym: "regulation of biological characteristic" EXACT []
is_a: GO:0065007 ! biological regulation

[Term]
id: GO:0065009
name: regulation of molecular function
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete]
subset: gocheck_do_not_annotate
subset: goslim_agr
subset: goslim_pir
subset: goslim_plant
synonym: "regulation of a molecular function" EXACT []
is_a: GO:0065007 ! biological regulation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0003674 ! molecular_function
relationship: regulates GO:0003674 ! molecular_function

[Term]
id: GO:0070570
name: regulation of neuron projection regeneration
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah]
is_a: GO:0010975 ! regulation of neuron projection development
is_a: GO:0080135 ! regulation of cellular response to stress
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0031102 ! neuron projection regeneration
relationship: regulates GO:0031102 ! neuron projection regeneration
created_by: midori
creation_date: 2009-04-15T01:23:48Z

[Term]
id: GO:0070571
name: negative regulation of neuron projection regeneration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah]
synonym: "growth cone collapse" RELATED [GOC:pr]
is_a: GO:0010977 ! negative regulation of neuron projection development
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:0070570 ! regulation of neuron projection regeneration
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0031102 ! neuron projection regeneration
relationship: negatively_regulates GO:0031102 ! neuron projection regeneration
created_by: midori
creation_date: 2009-04-15T01:43:19Z

[Term]
id: GO:0070572
name: positive regulation of neuron projection regeneration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah]
is_a: GO:0010976 ! positive regulation of neuron projection development
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:0070570 ! regulation of neuron projection regeneration
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0031102 ! neuron projection regeneration
relationship: positively_regulates GO:0031102 ! neuron projection regeneration
created_by: midori
creation_date: 2009-04-15T01:45:27Z

[Term]
id: GO:0070925
name: organelle assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah]
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization
is_a: GO:0022607 ! cellular component assembly
created_by: midori
creation_date: 2009-09-15T03:00:51Z

[Term]
id: GO:0070986
name: left/right axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes)." [GOC:dph, GOC:gvg, GOC:mah]
synonym: "left-right axis specification" EXACT [GOC:mah]
synonym: "left/right axis determination" RELATED [GOC:dph]
is_a: GO:0009798 ! axis specification
relationship: part_of GO:0060972 ! left/right pattern formation
created_by: midori
creation_date: 2009-10-29T01:43:34Z

[Term]
id: GO:0071684
name: organism emergence from protective structure
namespace: biological_process
def: "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." [GOC:mah]
is_a: GO:0032501 ! multicellular organismal process
created_by: midori
creation_date: 2010-02-19T04:23:55Z

[Term]
id: GO:0071840
name: cellular component organization or biogenesis
namespace: biological_process
alt_id: GO:0071841
def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah]
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah]
synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah]
synonym: "cellular component organization or biogenesis at cellular level" EXACT []
is_a: GO:0008150 ! biological_process
created_by: midori
creation_date: 2010-09-10T01:39:16Z

[Term]
id: GO:0071944
name: cell periphery
namespace: cellular_component
def: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." [GOC:mah]
subset: goslim_flybase_ribbon
is_a: GO:0044464 ! cell part
created_by: midori
creation_date: 2010-10-04T01:51:47Z

[Term]
id: GO:0080134
name: regulation of response to stress
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0006950 ! response to stress
relationship: regulates GO:0006950 ! response to stress
created_by: donghui
creation_date: 2009-05-06T04:51:28Z

[Term]
id: GO:0080135
name: regulation of cellular response to stress
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl]
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0080134 ! regulation of response to stress
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0033554 ! cellular response to stress
relationship: regulates GO:0033554 ! cellular response to stress
created_by: donghui
creation_date: 2009-05-06T05:02:52Z

[Term]
id: GO:0090068
name: positive regulation of cell cycle process
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0045787 ! positive regulation of cell cycle
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0022402 ! cell cycle process
relationship: positively_regulates GO:0022402 ! cell cycle process
created_by: tanyaberardini
creation_date: 2009-09-09T11:39:52Z

[Term]
id: GO:0090148
name: membrane fission
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "membrane scission" EXACT []
is_a: GO:0061024 ! membrane organization
created_by: tanyaberardini
creation_date: 2009-12-08T03:06:36Z

[Term]
id: GO:0097435
name: supramolecular fiber organization
namespace: biological_process
alt_id: GO:0043206
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr]
synonym: "extracellular fibril organisation" NARROW [GOC:curators]
synonym: "extracellular fibril organization" NARROW []
synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah]
synonym: "fibril organisation" RELATED []
synonym: "fibril organization" RELATED []
is_a: GO:0016043 ! cellular component organization
created_by: paola
creation_date: 2012-11-27T15:46:25Z

[Term]
id: GO:0097708
name: intracellular vesicle
namespace: cellular_component
def: "Any vesicle that is part of the intracellular region." [GOC:vesicles]
is_a: GO:0031982 ! vesicle
is_a: GO:0043229 ! intracellular organelle
intersection_of: GO:0031982 ! vesicle
intersection_of: part_of GO:0005622 ! intracellular
created_by: paola
creation_date: 2016-03-29T17:39:45Z

[Term]
id: GO:0098590
name: plasma membrane region
namespace: cellular_component
def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos]
comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
subset: gocheck_do_not_manually_annotate
synonym: "region of plasma membrane" EXACT []
is_a: GO:0016020 ! membrane
is_a: GO:0044459 ! plasma membrane part
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0005886 ! plasma membrane
created_by: davidos
creation_date: 2014-03-06T11:55:32Z

[Term]
id: GO:0098772
name: molecular function regulator
namespace: molecular_function
def: "A molecular function that modulates the activity of a gene product or complex.  Examples include enzyme regulators and channel regulators." [GOC:dos, GOC:pt]
subset: goslim_flybase_ribbon
is_a: GO:0003674 ! molecular_function
relationship: part_of GO:0065009 ! regulation of molecular function

[Term]
id: GO:0098796
name: membrane protein complex
namespace: cellular_component
def: "Any protein complex that is part of a membrane." [GOC:dos]
subset: goslim_metagenomics
is_a: GO:0032991 ! protein-containing complex
is_a: GO:0044425 ! membrane part
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: part_of GO:0016020 ! membrane

[Term]
id: GO:0098797
name: plasma membrane protein complex
namespace: cellular_component
def: "Any protein complex that is part of the plasma membrane." [GOC:dos]
is_a: GO:0044459 ! plasma membrane part
is_a: GO:0098796 ! membrane protein complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: part_of GO:0005886 ! plasma membrane

[Term]
id: GO:0098900
name: regulation of action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]
comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.
is_a: GO:0042391 ! regulation of membrane potential
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0001508 ! action potential
relationship: regulates GO:0001508 ! action potential

[Term]
id: GO:0098916
name: anterograde trans-synaptic signaling
namespace: biological_process
def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft" [GOC:dos]
is_a: GO:0099537 ! trans-synaptic signaling

[Term]
id: GO:0099080
name: supramolecular complex
namespace: cellular_component
def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos]
is_a: GO:0005575 ! cellular_component

[Term]
id: GO:0099081
name: supramolecular polymer
namespace: cellular_component
def: "A polymeric supramolecular structure." [GOC:dos]
is_a: GO:0099080 ! supramolecular complex

[Term]
id: GO:0099177
name: regulation of trans-synaptic signaling
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0099537 ! trans-synaptic signaling
relationship: regulates GO:0099537 ! trans-synaptic signaling

[Term]
id: GO:0099503
name: secretory vesicle
namespace: cellular_component
def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos]
is_a: GO:0031410 ! cytoplasmic vesicle

[Term]
id: GO:0099512
name: supramolecular fiber
namespace: cellular_component
alt_id: GO:0043205
def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos]
synonym: "fibril" RELATED []
is_a: GO:0099081 ! supramolecular polymer

[Term]
id: GO:0099513
name: polymeric cytoskeletal fiber
namespace: cellular_component
def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos]
is_a: GO:0044430 ! cytoskeletal part
is_a: GO:0099512 ! supramolecular fiber

[Term]
id: GO:0099536
name: synaptic signaling
namespace: biological_process
def: "Cell-cell signaling to, from or or within a synapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0007267 ! cell-cell signaling

[Term]
id: GO:0099537
name: trans-synaptic signaling
namespace: biological_process
def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos]
subset: goslim_synapse
is_a: GO:0099536 ! synaptic signaling

[Term]
id: GO:0099550
name: trans-synaptic signaling, modulating synaptic transmission
namespace: biological_process
def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099568
name: cytoplasmic region
namespace: cellular_component
def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm\"" [GOC:dos]
is_a: GO:0005737 ! cytoplasm
is_a: GO:0044444 ! cytoplasmic part
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0110020
name: regulation of actomyosin structure organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195]
is_a: GO:0032956 ! regulation of actin cytoskeleton organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0031032 ! actomyosin structure organization
relationship: regulates GO:0031032 ! actomyosin structure organization
created_by: kmv
creation_date: 2017-06-20T19:28:58Z

[Term]
id: GO:0120035
name: regulation of plasma membrane bounded cell projection organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc]
is_a: GO:0031344 ! regulation of cell projection organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0120036 ! plasma membrane bounded cell projection organization
relationship: regulates GO:0120036 ! plasma membrane bounded cell projection organization
created_by: kchris
creation_date: 2017-04-26T16:02:06Z

[Term]
id: GO:0120036
name: plasma membrane bounded cell projection organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc]
is_a: GO:0030030 ! cell projection organization
created_by: kchris
creation_date: 2017-04-26T16:07:02Z

[Term]
id: GO:0140014
name: mitotic nuclear division
namespace: biological_process
def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684]
subset: goslim_chembl
subset: goslim_generic
is_a: GO:0000280 ! nuclear division
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0000280 ! nuclear division
intersection_of: part_of GO:0000278 ! mitotic cell cycle
created_by: pg
creation_date: 2017-03-23T14:44:23Z

[Term]
id: GO:1900120
name: regulation of receptor binding
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie]
synonym: "regulation of receptor ligand" NARROW [GOC:TermGenie]
is_a: GO:0043393 ! regulation of protein binding
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0005102 ! signaling receptor binding
relationship: regulates GO:0005102 ! signaling receptor binding
created_by: bf
creation_date: 2012-02-22T11:40:53Z

[Term]
id: GO:1900121
name: negative regulation of receptor binding
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie]
synonym: "down regulation of receptor binding" EXACT [GOC:TermGenie]
synonym: "down regulation of receptor-associated protein activity" RELATED [GOC:TermGenie]
synonym: "down-regulation of receptor binding" EXACT [GOC:TermGenie]
synonym: "downregulation of receptor binding" EXACT [GOC:TermGenie]
synonym: "inhibition of receptor binding" NARROW [GOC:TermGenie]
synonym: "inhibition of receptor ligand" NARROW [GOC:TermGenie]
is_a: GO:0032091 ! negative regulation of protein binding
is_a: GO:1900120 ! regulation of receptor binding
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0005102 ! signaling receptor binding
relationship: negatively_regulates GO:0005102 ! signaling receptor binding
created_by: bf
creation_date: 2012-02-22T11:40:57Z

[Term]
id: GO:1900122
name: positive regulation of receptor binding
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie]
synonym: "activation of receptor binding" NARROW [GOC:TermGenie]
synonym: "up regulation of receptor binding" EXACT [GOC:TermGenie]
synonym: "upregulation of receptor binding" EXACT [GOC:TermGenie]
is_a: GO:0032092 ! positive regulation of protein binding
is_a: GO:1900120 ! regulation of receptor binding
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0005102 ! signaling receptor binding
relationship: positively_regulates GO:0005102 ! signaling receptor binding
created_by: bf
creation_date: 2012-02-22T11:41:00Z

[Term]
id: GO:1902115
name: regulation of organelle assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0044087 ! regulation of cellular component biogenesis
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0070925 ! organelle assembly
relationship: regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:21Z

[Term]
id: GO:1902116
name: negative regulation of organelle assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0070925 ! organelle assembly
relationship: negatively_regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:31Z

[Term]
id: GO:1902117
name: positive regulation of organelle assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
synonym: "activation of organelle assembly" NARROW [GOC:TermGenie]
synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0070925 ! organelle assembly
relationship: positively_regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:36Z

[Term]
id: GO:1902412
name: regulation of mitotic cytokinesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mitotic cytokinesis." [GOC:mtg_cell_cycle, GOC:TermGenie]
synonym: "regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0032465 ! regulation of cytokinesis
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0000281 ! mitotic cytokinesis
relationship: regulates GO:0000281 ! mitotic cytokinesis
created_by: jl
creation_date: 2013-09-12T14:11:49Z

[Term]
id: GO:1902413
name: negative regulation of mitotic cytokinesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis." [GOC:mtg_cell_cycle, GOC:TermGenie]
synonym: "down regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "down regulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
synonym: "downregulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "downregulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
synonym: "inhibition of cytokinesis after mitosis" NARROW [GOC:TermGenie]
synonym: "inhibition of mitotic cytokinesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
is_a: GO:0032466 ! negative regulation of cytokinesis
is_a: GO:0045930 ! negative regulation of mitotic cell cycle
is_a: GO:1902412 ! regulation of mitotic cytokinesis
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0000281 ! mitotic cytokinesis
relationship: negatively_regulates GO:0000281 ! mitotic cytokinesis
created_by: jl
creation_date: 2013-09-12T14:11:59Z

[Term]
id: GO:1902531
name: regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010627
def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "regulation of intracellular protein kinase cascade" NARROW []
synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie]
synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009966 ! regulation of signal transduction
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0035556 ! intracellular signal transduction
relationship: regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:32:52Z

[Term]
id: GO:1902532
name: negative regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010741
def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie]
synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "negative regulation of intracellular protein kinase cascade" EXACT []
synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009968 ! negative regulation of signal transduction
is_a: GO:1902531 ! regulation of intracellular signal transduction
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0035556 ! intracellular signal transduction
relationship: negatively_regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:33:01Z

[Term]
id: GO:1902533
name: positive regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010740
def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "positive regulation of intracellular protein kinase cascade" NARROW []
synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009967 ! positive regulation of signal transduction
is_a: GO:1902531 ! regulation of intracellular signal transduction
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0035556 ! intracellular signal transduction
relationship: positively_regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:33:10Z

[Term]
id: GO:1902903
name: regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0097435 ! supramolecular fiber organization
relationship: regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:36Z

[Term]
id: GO:1902904
name: negative regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie]
synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0097435 ! supramolecular fiber organization
relationship: negatively_regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:42Z

[Term]
id: GO:1902905
name: positive regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "activation of fibril organisation" NARROW [GOC:TermGenie]
synonym: "activation of fibril organization" NARROW [GOC:TermGenie]
synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0097435 ! supramolecular fiber organization
relationship: positively_regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:48Z

[Term]
id: GO:1903034
name: regulation of response to wounding
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535]
synonym: "regulation of physiological response to wounding" EXACT [GOC:TermGenie]
is_a: GO:0080134 ! regulation of response to stress
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0009611 ! response to wounding
relationship: regulates GO:0009611 ! response to wounding
created_by: kmv
creation_date: 2014-05-18T01:28:46Z

[Term]
id: GO:1903035
name: negative regulation of response to wounding
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535]
synonym: "down regulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "down regulation of response to wounding" EXACT [GOC:TermGenie]
synonym: "down-regulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "down-regulation of response to wounding" EXACT [GOC:TermGenie]
synonym: "downregulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "downregulation of response to wounding" EXACT [GOC:TermGenie]
synonym: "inhibition of physiological response to wounding" NARROW [GOC:TermGenie]
synonym: "inhibition of response to wounding" NARROW [GOC:TermGenie]
synonym: "negative regulation of physiological response to wounding" EXACT [GOC:TermGenie]
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:1903034 ! regulation of response to wounding
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0009611 ! response to wounding
relationship: negatively_regulates GO:0009611 ! response to wounding
created_by: kmv
creation_date: 2014-05-18T01:28:52Z

[Term]
id: GO:1903036
name: positive regulation of response to wounding
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535]
synonym: "activation of physiological response to wounding" NARROW [GOC:TermGenie]
synonym: "activation of response to wounding" NARROW [GOC:TermGenie]
synonym: "positive regulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "up regulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "up regulation of response to wounding" EXACT [GOC:TermGenie]
synonym: "up-regulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "up-regulation of response to wounding" EXACT [GOC:TermGenie]
synonym: "upregulation of physiological response to wounding" EXACT [GOC:TermGenie]
synonym: "upregulation of response to wounding" EXACT [GOC:TermGenie]
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:1903034 ! regulation of response to wounding
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0009611 ! response to wounding
relationship: positively_regulates GO:0009611 ! response to wounding
created_by: kmv
creation_date: 2014-05-18T01:28:58Z

[Term]
id: GO:1903047
name: mitotic cell cycle process
namespace: biological_process
def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie]
subset: gocheck_do_not_annotate
is_a: GO:0022402 ! cell cycle process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0000278 ! mitotic cell cycle
relationship: part_of GO:0000278 ! mitotic cell cycle
created_by: jl
creation_date: 2014-05-22T14:22:34Z

[Term]
id: GO:1903490
name: positive regulation of mitotic cytokinesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis." [GO_REF:0000058, GOC:TermGenie, PMID:24920823]
synonym: "activation of cytokinesis after mitosis" NARROW [GOC:TermGenie]
synonym: "activation of mitotic cytokinesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "up regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "up regulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
synonym: "upregulation of cytokinesis after mitosis" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic cytokinesis" EXACT [GOC:TermGenie]
is_a: GO:0032467 ! positive regulation of cytokinesis
is_a: GO:0045931 ! positive regulation of mitotic cell cycle
is_a: GO:1902412 ! regulation of mitotic cytokinesis
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0000281 ! mitotic cytokinesis
relationship: positively_regulates GO:0000281 ! mitotic cytokinesis
created_by: al
creation_date: 2014-09-25T09:00:35Z

[Term]
id: GO:1905902
name: regulation of mesoderm formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
is_a: GO:0010470 ! regulation of gastrulation
is_a: GO:2000380 ! regulation of mesoderm development
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0001707 ! mesoderm formation
relationship: regulates GO:0001707 ! mesoderm formation
created_by: rachhuntley
creation_date: 2017-02-03T12:28:20Z

[Term]
id: GO:1905903
name: negative regulation of mesoderm formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie]
is_a: GO:1905902 ! regulation of mesoderm formation
is_a: GO:2000381 ! negative regulation of mesoderm development
is_a: GO:2000542 ! negative regulation of gastrulation
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0001707 ! mesoderm formation
relationship: negatively_regulates GO:0001707 ! mesoderm formation
created_by: rachhuntley
creation_date: 2017-02-03T12:28:29Z

[Term]
id: GO:1905904
name: positive regulation of mesoderm formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie]
synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie]
is_a: GO:1905902 ! regulation of mesoderm formation
is_a: GO:2000382 ! positive regulation of mesoderm development
is_a: GO:2000543 ! positive regulation of gastrulation
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0001707 ! mesoderm formation
relationship: positively_regulates GO:0001707 ! mesoderm formation
created_by: rachhuntley
creation_date: 2017-02-03T12:28:38Z

[Term]
id: GO:2000026
name: regulation of multicellular organismal development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007275 ! multicellular organism development
relationship: regulates GO:0007275 ! multicellular organism development
created_by: tanyaberardini
creation_date: 2010-08-05T11:25:59Z

[Term]
id: GO:2000035
name: regulation of stem cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol]
synonym: "regulation of stem cell renewal" EXACT [GOC:obol]
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0017145 ! stem cell division
relationship: regulates GO:0017145 ! stem cell division
created_by: tanyaberardini
creation_date: 2010-08-05T11:34:53Z

[Term]
id: GO:2000145
name: regulation of cell motility
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "regulation of cell locomotion" EXACT [GOC:obol]
synonym: "regulation of cell movement" RELATED [GOC:obol]
synonym: "regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0051270 ! regulation of cellular component movement
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0048870 ! cell motility
relationship: regulates GO:0048870 ! cell motility
created_by: midori
creation_date: 2010-10-01T09:41:21Z

[Term]
id: GO:2000146
name: negative regulation of cell motility
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "negative regulation of cell locomotion" EXACT [GOC:obol]
synonym: "negative regulation of cell movement" RELATED [GOC:obol]
synonym: "negative regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040013 ! negative regulation of locomotion
is_a: GO:0051271 ! negative regulation of cellular component movement
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0048870 ! cell motility
relationship: negatively_regulates GO:0048870 ! cell motility
created_by: midori
creation_date: 2010-10-01T09:41:26Z

[Term]
id: GO:2000147
name: positive regulation of cell motility
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "positive regulation of cell locomotion" EXACT [GOC:obol]
synonym: "positive regulation of cell movement" RELATED [GOC:obol]
synonym: "positive regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040017 ! positive regulation of locomotion
is_a: GO:0051272 ! positive regulation of cellular component movement
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0048870 ! cell motility
relationship: positively_regulates GO:0048870 ! cell motility
created_by: midori
creation_date: 2010-10-01T09:41:30Z

[Term]
id: GO:2000177
name: regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0061351 ! neural precursor cell proliferation
relationship: regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:41Z

[Term]
id: GO:2000178
name: negative regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0061351 ! neural precursor cell proliferation
relationship: negatively_regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:43Z

[Term]
id: GO:2000179
name: positive regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0061351 ! neural precursor cell proliferation
relationship: positively_regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:45Z

[Term]
id: GO:2000241
name: regulation of reproductive process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0022414 ! reproductive process
relationship: regulates GO:0022414 ! reproductive process
created_by: midori
creation_date: 2010-11-10T02:44:02Z

[Term]
id: GO:2000242
name: negative regulation of reproductive process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0022414 ! reproductive process
relationship: negatively_regulates GO:0022414 ! reproductive process
created_by: midori
creation_date: 2010-11-10T02:44:05Z

[Term]
id: GO:2000243
name: positive regulation of reproductive process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0022414 ! reproductive process
relationship: positively_regulates GO:0022414 ! reproductive process
created_by: midori
creation_date: 2010-11-10T02:44:08Z

[Term]
id: GO:2000272
name: negative regulation of signaling receptor activity
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity." [GOC:obol]
synonym: "negative regulation of receptor activity" BROAD []
is_a: GO:0010469 ! regulation of signaling receptor activity
is_a: GO:0044092 ! negative regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0038023 ! signaling receptor activity
relationship: negatively_regulates GO:0038023 ! signaling receptor activity
created_by: rfoulger
creation_date: 2010-12-02T09:28:47Z

[Term]
id: GO:2000273
name: positive regulation of signaling receptor activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of signaling receptor activity." [GOC:obol]
is_a: GO:0010469 ! regulation of signaling receptor activity
is_a: GO:0044093 ! positive regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0038023 ! signaling receptor activity
relationship: positively_regulates GO:0038023 ! signaling receptor activity
created_by: rfoulger
creation_date: 2010-12-02T09:28:50Z

[Term]
id: GO:2000380
name: regulation of mesoderm development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007498 ! mesoderm development
relationship: regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:09:46Z

[Term]
id: GO:2000381
name: negative regulation of mesoderm development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:2000380 ! regulation of mesoderm development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007498 ! mesoderm development
relationship: negatively_regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:10:02Z

[Term]
id: GO:2000382
name: positive regulation of mesoderm development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:2000380 ! regulation of mesoderm development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007498 ! mesoderm development
relationship: positively_regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:10:12Z

[Term]
id: GO:2000383
name: regulation of ectoderm development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007398 ! ectoderm development
relationship: regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:10Z

[Term]
id: GO:2000384
name: negative regulation of ectoderm development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:2000383 ! regulation of ectoderm development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007398 ! ectoderm development
relationship: negatively_regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:27Z

[Term]
id: GO:2000385
name: positive regulation of ectoderm development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:2000383 ! regulation of ectoderm development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007398 ! ectoderm development
relationship: positively_regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:39Z

[Term]
id: GO:2000542
name: negative regulation of gastrulation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol]
is_a: GO:0010470 ! regulation of gastrulation
is_a: GO:0045992 ! negative regulation of embryonic development
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007369 ! gastrulation
relationship: negatively_regulates GO:0007369 ! gastrulation
created_by: yaf
creation_date: 2011-04-01T04:10:08Z

[Term]
id: GO:2000543
name: positive regulation of gastrulation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol]
is_a: GO:0010470 ! regulation of gastrulation
is_a: GO:0040019 ! positive regulation of embryonic development
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007369 ! gastrulation
relationship: positively_regulates GO:0007369 ! gastrulation
created_by: yaf
creation_date: 2011-04-01T04:10:15Z

[Term]
id: IAO:0000027
name: data item
def: "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." []
is_a: IAO:0000030 ! information content entity
property_value: IAO:0000111 "data item" xsd:string
property_value: IAO:0000112 "Data items include counts of things, analyte concentrations, and statistical summaries." xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000116 "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers." xsd:string
property_value: IAO:0000116 "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum." xsd:string
property_value: IAO:0000116 "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym." xsd:string
property_value: IAO:0000116 "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/" xsd:string
property_value: IAO:0000116 "JAR: datum     -- well, this will be very tricky to define, but maybe some \ninformation-like stuff that might be put into a computer and that is \nmeant, by someone, to denote and/or to be interpreted by some \nprocess... I would include lists, tables, sentences... I think I might \ndefer to Barry, or to Brian Cantwell Smith\n\nJAR: A data item is an approximately justified approximately true approximate belief" xsd:string
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string
property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string
property_value: IAO:0000118 "data" xsd:string

[Term]
id: IAO:0000030
name: information content entity
def: "A generically dependent continuant that is about some thing." []
is_a: BFO:0000031 ! generically dependent continuant
relationship: IAO:0000136 BFO:0000001 ! is about entity
property_value: IAO:0000111 "information content entity" xsd:string
property_value: IAO:0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs." xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000116 "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)." xsd:string
property_value: IAO:0000116 "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).\n\nPrevious. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity." xsd:string
property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string
property_value: IAO:0000119 "OBI_0000142" xsd:string

[Term]
id: IAO:0000078
name: curation status specification
def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." []
is_a: IAO:0000102 ! data about an ontology part
property_value: IAO:0000111 "curation status specification" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000116 "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string
property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string
property_value: IAO:0000119 GROUP:OBI:<http://purl.obolibrary.org/obo/obi> xsd:string
property_value: IAO:0000119 "OBI_0000266" xsd:string

[Term]
id: IAO:0000102
name: data about an ontology part
def: "data about an ontology part is a data item about a part of an ontology, for example a term" []
is_a: IAO:0000027 ! data item
property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string

[Term]
id: IAO:0000225
name: obsolescence reason specification
def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." []
is_a: IAO:0000102 ! data about an ontology part
property_value: IAO:0000111 "obsolescence reason specification" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000116 "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string

[Term]
id: IAO:0000409
name: denotator type
def: "A denotator type indicates how a term should be interpreted from an ontological perspective." []
is_a: IAO:0000102 ! data about an ontology part
property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string
property_value: IAO:0000117 "Alan Ruttenberg" xsd:string
property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string

[Term]
id: PATO:0000001
name: quality
namespace: quality
alt_id: PATO:0000072
def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG]
synonym: "trait" EXACT []
is_a: BFO:0000020 ! specifically dependent continuant
property_value: IAO:0000589 "quality (PATO)" xsd:string

[Term]
id: PATO:0000004
name: mobility
namespace: quality
def: "A quality of inhering in a bearer by virtue of the bearer's disposition to move freely." [PATOC:GVG]
comment: Should be defined using translocation.
subset: attribute_slim
subset: disposition_slim
subset: scalar_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0000014
name: color
namespace: quality
alt_id: PATO:0000020
def: "A composite chromatic quality composed of hue, saturation and intensity parts." [PATOC:GVG]
subset: attribute_slim
synonym: "colour" EXACT []
synonym: "relative color" EXACT []
is_a: PATO:0001300 ! optical quality

[Term]
id: PATO:0000025
name: composition
namespace: quality
alt_id: PATO:0002015
def: "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." [PATOC:GVG]
comment: For example calcium composition (which may inhere in bone), haemoglobin composition (which may inhere in blood).
subset: attribute_slim
subset: scalar_slim
synonym: "composed of" EXACT []
synonym: "compositionality" EXACT []
synonym: "content" EXACT []
synonym: "structure, composition" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0000040
name: distance
namespace: quality
def: "A quality that is the extent of space between two entities." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
subset: scalar_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0000047
name: biological sex
namespace: quality
def: "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." [MGED:MGED]
subset: attribute_slim
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0000051
name: morphology
namespace: quality
def: "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." [PATOC:GVG]
subset: attribute_slim
is_a: BFO:0000019 ! quality
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0000052
name: shape
namespace: quality
alt_id: PATO:0001647
def: "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." [PATOC:GVG]
comment: Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects.
subset: attribute_slim
synonym: "relational shape quality" EXACT []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000057
name: occurrence
namespace: quality
alt_id: PATO:0000156
alt_id: PATO:0000158
def: "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence." [PATOC:GVG]
subset: attribute_slim
subset: hpo_slim
synonym: "incidence" EXACT []
synonym: "temporal" BROAD []
is_a: PATO:0002323 ! temporal distribution quality

[Term]
id: PATO:0000060
name: spatial pattern
namespace: quality
alt_id: PATO:0000132
alt_id: PATO:0001565
def: "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." [PATOC:GVG]
subset: attribute_slim
subset: hpo_slim
synonym: "distribution" EXACT []
synonym: "pattern" RELATED []
is_a: PATO:0000140 ! position

[Term]
id: PATO:0000068
name: qualitative
namespace: quality
comment: TODO: define this or obsolete it and move children somewhere else.
is_a: PATO:0000001 ! quality

[Term]
id: PATO:0000069
name: deviation(from_normal)
namespace: quality
def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000068 ! qualitative

[Term]
id: PATO:0000070
name: amount
namespace: quality
alt_id: PATO:0000053
alt_id: PATO:0000071
alt_id: PATO:0001169
alt_id: PATO:0001226
def: "The number of entities of this type that are part of the whole organism." [PATOC:GVG]
comment: This term was originally named "presence". It has been renamed to reduce ambiguity. Consider annotating with the reciprocal relation,PATO:0001555, has_number_of. For example, rather than E=fin ray Q=count in organism C=10, say E=organism Q=has number of E2= fin ray C=10.
subset: attribute_slim
synonym: "count" EXACT []
synonym: "count in organism" RELATED []
synonym: "number" RELATED []
synonym: "presence" RELATED []
synonym: "presence or absence in organism" EXACT []
synonym: "quantitative" EXACT []
is_a: PATO:0000068 ! qualitative
relationship: reciprocal_of PATO:0001555 ! has number of

[Term]
id: PATO:0000083
name: phase
namespace: quality
def: "A quality that exists by virtue of being a particular point in the time of a cycle." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0002323 ! temporal distribution quality

[Term]
id: PATO:0000117
name: size
namespace: quality
def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000119
name: height
namespace: quality
def: "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension." [PATOC:GVG]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0001708 ! 1-D extent

[Term]
id: PATO:0000122
name: length
namespace: quality
def: "A 1-D extent quality which is equal to the distance between two points." [PATOC:GVG]
subset: attribute_slim
subset: mpath_slim
subset: scalar_slim
is_a: PATO:0001708 ! 1-D extent
property_value: IAO:0000111 "length" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl

[Term]
id: PATO:0000125
name: mass
namespace: quality
def: "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
subset: scalar_slim
is_a: BFO:0000019 ! quality
is_a: PATO:0001018 ! physical quality
property_value: IAO:0000111 "mass" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl

[Term]
id: PATO:0000133
name: orientation
namespace: quality
alt_id: PATO:0000137
def: "A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object." [PATOC:JE]
subset: attribute_slim
subset: relational_slim
synonym: "amount of rotation" RELATED []
synonym: "angle" RELATED []
synonym: "angular magnitude" RELATED []
synonym: "angular placement" EXACT []
synonym: "plane angle" RELATED []
is_a: PATO:0000140 ! position

[Term]
id: PATO:0000136
name: closure
namespace: quality
def: "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." [PATOC:CJM, PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000140
name: position
namespace: quality
alt_id: PATO:0001032
alt_id: PATO:0001631
def: "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." [PATOC:GVG]
subset: attribute_slim
synonym: "location" EXACT []
synonym: "placement" EXACT []
synonym: "relational spatial quality" EXACT []
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0000141
name: structure
namespace: quality
alt_id: PATO:0001452
def: "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." [PATOC:GVG]
subset: attribute_slim
synonym: "conformation" BROAD [VT:1000738]
synonym: "relational structural quality" EXACT []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000150
name: texture
namespace: quality
def: "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000161
name: rate
namespace: quality
def: "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." [PATOC:melissa]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0002062 ! physical quality of a process

[Term]
id: PATO:0000169
name: viability
namespace: quality
def: "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." [PATOC:GVG]
subset: attribute_slim
subset: disposition_slim
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0000186
name: behavioral quality
namespace: quality
alt_id: PATO:0001722
def: "An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation." [PATOC:GVG]
synonym: "behavioural quality" EXACT []
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0000261
name: maturity
namespace: quality
def: "A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development." [Merriam-Webster:Merriam-Webster]
subset: attribute_slim
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0000297
name: arrested
namespace: quality
alt_id: PATO:0001508
def: "A quality of a process which ends earlier than the natural end time or reference process." [PATOC:LC]
comment: TODO: the definition is incorrect. See absent.
subset: value_slim
synonym: "abolished" EXACT []
synonym: "incomplete" RELATED []
is_a: PATO:0002052 ! decreased occurrence
is_a: PATO:0002324 ! offset quality

[Term]
id: PATO:0000299
name: mobile
namespace: quality
def: "A mobility quality of inhering in a bearer by virtue of the bearer's disposition to move freely." [PATOC:GVG]
subset: disposition_slim
subset: value_slim
is_a: PATO:0000004 ! mobility
disjoint_from: PATO:0000300 ! immobile
relationship: is_opposite_of PATO:0000300 ! immobile

[Term]
id: PATO:0000300
name: immobile
namespace: quality
def: "A mobility quality inhering in a bearer by virtue of the bearer's being incapable to move freely." [PATOC:GVG]
subset: disposition_slim
subset: value_slim
synonym: "fixed" RELATED []
is_a: PATO:0000004 ! mobility
relationship: is_opposite_of PATO:0000299 ! mobile

[Term]
id: PATO:0000330
name: irregular spatial pattern
namespace: quality
def: "A spatial pattern inhering in a bearer by virtue of the bearer's magnitude of or the relationships between its repeated parts lack consistency." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0000060 ! spatial pattern
relationship: is_opposite_of PATO:0000440 ! regular spatial pattern

[Term]
id: PATO:0000374
name: increased distance
namespace: quality
def: "A distance which is greater relative to the normal or average." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "long distance" RELATED []
is_a: PATO:0000040 ! distance
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000040 ! distance
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000375 ! decreased distance

[Term]
id: PATO:0000375
name: decreased distance
namespace: quality
def: "A distance which is lesser relative to the normal or average." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "short distance" RELATED []
is_a: PATO:0000040 ! distance
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000040 ! distance
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000374 ! increased distance

[Term]
id: PATO:0000402
name: branched
namespace: quality
def: "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "ramified" EXACT []
synonym: "ramiform" EXACT []
is_a: PATO:0002009 ! branchiness
disjoint_from: PATO:0000414 ! unbranched
relationship: is_opposite_of PATO:0000414 ! unbranched

[Term]
id: PATO:0000404
name: coiled
namespace: quality
alt_id: PATO:0001363
def: "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "helical" RELATED []
synonym: "helicoid" RELATED []
synonym: "helicoidal" RELATED []
synonym: "helix-shaped" RELATED []
synonym: "spiral" EXACT []
is_a: PATO:0001794 ! coiling
relationship: is_opposite_of PATO:0000415 ! uncoiled

[Term]
id: PATO:0000406
name: curved
namespace: quality
def: "A curvature quality inhering in a bearer by virtue of the bearer's having or being marked by a curve or smoothly rounded bend." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
synonym: "bowing" NARROW []
synonym: "curled" RELATED []
is_a: PATO:0001591 ! curvature

[Term]
id: PATO:0000411
name: circular
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." [thefreedictionary.com:thefreedictionary.com]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "round" RELATED []
synonym: "rounded" RELATED []
is_a: PATO:0000947 ! elliptic

[Term]
id: PATO:0000414
name: unbranched
namespace: quality
def: "A branchiness quality inhering in a bearer by virtue of the bearer's lacking branches." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0002009 ! branchiness
relationship: is_opposite_of PATO:0000402 ! branched

[Term]
id: PATO:0000415
name: uncoiled
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being not curled or wound (especially in concentric rings or spirals)." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001794 ! coiling
relationship: is_opposite_of PATO:0000404 ! coiled

[Term]
id: PATO:0000440
name: regular spatial pattern
namespace: quality
def: "A pattern quality inhering in a bearer by virtue of the bearer's having a repeatable or predictable placement." [PATOC:GVG]
subset: mpath_slim
subset: relational_slim
subset: value_slim
is_a: PATO:0000060 ! spatial pattern
relationship: is_opposite_of PATO:0000330 ! irregular spatial pattern

[Term]
id: PATO:0000460
name: abnormal
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's deviation from normal or average." [PATOC:GVG]
subset: abnormal_slim
subset: mpath_slim
subset: value_slim
synonym: "aberrant" RELATED []
synonym: "atypia" RELATED []
synonym: "atypical" RELATED []
synonym: "defective" RELATED []
is_a: PATO:0000069 ! deviation(from_normal)
relationship: is_opposite_of PATO:0000461 ! normal

[Term]
id: PATO:0000461
name: normal
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG]
subset: abnormal_slim
subset: mpath_slim
subset: value_slim
synonym: "average" RELATED []
is_a: PATO:0000069 ! deviation(from_normal)
relationship: is_opposite_of PATO:0000460 ! abnormal

[Term]
id: PATO:0000462
name: absent
namespace: quality
alt_id: PATO:0001996
def: "A quality denoting the lack of an entity." [thefreedictionary.:thefreedictionary.]
comment: See documentation here: http://code.google.com/p/phenotype-ontologies/wiki/ModelingOfAbsence
subset: absent_slim
subset: mpath_slim
subset: value_slim
synonym: "absence" EXACT []
synonym: "absent from organism" EXACT []
is_a: PATO:0000070 ! amount
disjoint_from: PATO:0000467 ! present
relationship: is_opposite_of PATO:0000467 ! present
relationship: reciprocal_of PATO:0001558 ! lacking processual parts
relationship: reciprocal_of PATO:0002000 ! lacks all parts of type

[Term]
id: PATO:0000467
name: present
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's existence." [PATOC:GVG]
subset: absent_slim
subset: value_slim
synonym: "present in organism" RELATED []
is_a: PATO:0000070 ! amount
relationship: is_opposite_of PATO:0000462 ! absent

[Term]
id: PATO:0000470
name: increased amount
namespace: quality
alt_id: PATO:0000420
alt_id: PATO:0000650
def: "An amount which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "accessory" RELATED []
synonym: "increased" RELATED []
synonym: "increased number" EXACT []
synonym: "present in greater numbers in organism" EXACT []
synonym: "supernumerary" EXACT []
is_a: PATO:0000467 ! present
is_a: PATO:0002300 ! increased quality
intersection_of: PATO:0000070 ! amount
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001997 ! decreased amount

[Term]
id: PATO:0000502
name: delayed
namespace: quality
def: "A quality of a process which starts later than the natural start time or the reference process." [PATOC:LC]
subset: value_slim
synonym: "late" RELATED []
is_a: PATO:0002325 ! onset quality

[Term]
id: PATO:0000569
name: decreased height
namespace: quality
def: "A height which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "short" RELATED []
is_a: PATO:0000119 ! height
is_a: PATO:0000587 ! decreased size
intersection_of: PATO:0000119 ! height
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000570 ! increased height

[Term]
id: PATO:0000570
name: increased height
namespace: quality
def: "A height which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "tall" RELATED []
is_a: PATO:0000119 ! height
is_a: PATO:0000586 ! increased size
intersection_of: PATO:0000119 ! height
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000569 ! decreased height

[Term]
id: PATO:0000573
name: increased length
namespace: quality
def: "A length quality which is relatively large." [PATOC:GVG]
subset: value_slim
synonym: "long" EXACT []
is_a: PATO:0000122 ! length
is_a: PATO:0000586 ! increased size
intersection_of: PATO:0000122 ! length
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000574 ! decreased length

[Term]
id: PATO:0000574
name: decreased length
namespace: quality
def: "A length quality which is relatively small." [PATOC:GVG]
subset: value_slim
synonym: "short" EXACT []
synonym: "shortened" RELATED []
synonym: "stubby" RELATED []
is_a: PATO:0000122 ! length
is_a: PATO:0000587 ! decreased size
intersection_of: PATO:0000122 ! length
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000573 ! increased length

[Term]
id: PATO:0000584
name: hypertrophic
namespace: quality
def: "An increased size quality inhering in a bearer by virtue of the bearer's exhibiting enlargement of a cell or constituent group of cells (for example, organ)." [PATOC:MAH]
subset: mpath_slim
subset: value_slim
synonym: "hypertrophy" NARROW []
is_a: PATO:0000595 ! increased volume
relationship: is_opposite_of PATO:0000585 ! hypotrophic

[Term]
id: PATO:0000585
name: hypotrophic
namespace: quality
alt_id: PATO:0000412
def: "A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced size of a cell or constituent group of cells (for example, organ)." [PATOC:MAH]
subset: mpath_slim
subset: value_slim
synonym: "shrunken" EXACT []
is_a: PATO:0000596 ! decreased volume
relationship: is_opposite_of PATO:0000584 ! hypertrophic

[Term]
id: PATO:0000586
name: increased size
namespace: quality
alt_id: PATO:0001202
def: "A size quality which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "big" RELATED []
synonym: "enlarged" RELATED []
synonym: "expanded" RELATED []
synonym: "great" RELATED []
synonym: "large" RELATED []
is_a: PATO:0000117 ! size
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000117 ! size
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000587 ! decreased size

[Term]
id: PATO:0000587
name: decreased size
namespace: quality
def: "A size quality which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "hypoplasia" NARROW []
synonym: "reduced" RELATED []
synonym: "small" RELATED []
synonym: "tiny" RELATED []
synonym: "underdeveloped" NARROW []
is_a: PATO:0000117 ! size
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000117 ! size
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000586 ! increased size

[Term]
id: PATO:0000591
name: increased thickness
namespace: quality
def: "A thickness which is relatively high." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "high thickness" EXACT []
synonym: "stout" EXACT []
synonym: "thick" RELATED []
synonym: "thickened" EXACT []
is_a: PATO:0000586 ! increased size
is_a: PATO:0000915 ! thickness
intersection_of: PATO:0000915 ! thickness
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000592 ! decreased thickness

[Term]
id: PATO:0000592
name: decreased thickness
namespace: quality
def: "A thickness which is relatively low." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "low thickness" EXACT []
synonym: "slender" RELATED []
synonym: "thin" RELATED []
is_a: PATO:0000587 ! decreased size
is_a: PATO:0000915 ! thickness
intersection_of: PATO:0000915 ! thickness
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000591 ! increased thickness

[Term]
id: PATO:0000595
name: increased volume
namespace: quality
def: "A volume which is relatively high." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "high volume" EXACT []
synonym: "large volume" RELATED []
is_a: PATO:0000586 ! increased size
is_a: PATO:0000918 ! volume
intersection_of: PATO:0000918 ! volume
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000596 ! decreased volume

[Term]
id: PATO:0000596
name: decreased volume
namespace: quality
def: "A volume which is relatively low." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "low volume" EXACT []
synonym: "small volume" RELATED []
is_a: PATO:0000587 ! decreased size
is_a: PATO:0000918 ! volume
intersection_of: PATO:0000918 ! volume
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000595 ! increased volume

[Term]
id: PATO:0000599
name: decreased width
namespace: quality
def: "A width which is relatively small." [PATOC:GVG]
subset: value_slim
synonym: "narrow" RELATED []
is_a: PATO:0000587 ! decreased size
is_a: PATO:0000921 ! width
intersection_of: PATO:0000921 ! width
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000600 ! increased width

[Term]
id: PATO:0000600
name: increased width
namespace: quality
def: "A width which is relatively large." [PATOC:GVG]
subset: value_slim
synonym: "broad" RELATED []
synonym: "wide" RELATED []
synonym: "wide/broad" RELATED []
is_a: PATO:0000586 ! increased size
is_a: PATO:0000921 ! width
intersection_of: PATO:0000921 ! width
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000599 ! decreased width

[Term]
id: PATO:0000608
name: closed
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." [answers.com:answers.com]
subset: value_slim
synonym: "blocked" RELATED []
is_a: PATO:0000136 ! closure
disjoint_from: PATO:0000610 ! open
relationship: is_opposite_of PATO:0000610 ! open

[Term]
id: PATO:0000609
name: closure incomplete
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's affording not completed blocked passage or view." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000610 ! open

[Term]
id: PATO:0000610
name: open
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's affording unobstructed passage or view." [answers.com:answers.com]
subset: value_slim
is_a: PATO:0000136 ! closure
relationship: is_opposite_of PATO:0000608 ! closed

[Term]
id: PATO:0000613
name: disoriented
namespace: quality
def: "A spatial pattern inhering in a bearer by virtue of the bearer's lacking orientation." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000330 ! irregular spatial pattern
relationship: is_opposite_of PATO:0000614 ! oriented

[Term]
id: PATO:0000614
name: oriented
namespace: quality
def: "A pattern where all the repeated elements are oriented in the same direction." [PATOC:MAH]
subset: value_slim
is_a: PATO:0000440 ! regular spatial pattern
relationship: is_opposite_of PATO:0000613 ! disoriented

[Term]
id: PATO:0000615
name: wholly anterioralized
namespace: quality
def: "An anterioralized quality inhering in a bearer by virtue of the bearer's gross morphology containing only what are normally anterior structures." [PATOC:GVG]
subset: value_slim
synonym: "anterioralized" RELATED []
is_a: PATO:0030000 ! anterioralized

[Term]
id: PATO:0000617
name: bent
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's having one or more angle(s) in its length." [PATOC:MAH]
subset: value_slim
synonym: "angled" EXACT []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0000620
name: wholly dorsalized
namespace: quality
def: "A dorsalized quality inhering in a bearer by virtue of the bearer's gross morphology containing only what are normally dorsal structures." [PATOC:melissa]
subset: mpath_slim
subset: value_slim
synonym: "dorsalized" RELATED []
is_a: PATO:0030001 ! dorsalized

[Term]
id: PATO:0000622
name: erect
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being upright in position or posture." [WordNet:WordNet]
subset: value_slim
synonym: "upright" EXACT []
is_a: PATO:0000140 ! position

[Term]
id: PATO:0000625
name: inverted
namespace: quality
def: "An oriented quality inhering in a bearer by virtue of the bearer's being reversed in position, order, or condition." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "backward" RELATED []
synonym: "reversed" RELATED []
is_a: PATO:0000614 ! oriented

[Term]
id: PATO:0000628
name: mislocalised
namespace: quality
alt_id: PATO:0000621
def: "A positional quality inhering in a bearer by virtue the bearer's being changed in abnormal position." [PATOC:GVG]
subset: disposition_slim
subset: value_slim
synonym: "ectopic" EXACT []
synonym: "mislocalized" EXACT []
is_a: PATO:0002181 ! displaced

[Term]
id: PATO:0000630
name: wholly posterioralized
namespace: quality
def: "A posterioralized quality inhering in a bearer by virtue of the bearer's gross morphology containing only what are normally posterior structures." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "posterioralized" RELATED []
is_a: PATO:0030002 ! posterioralized

[Term]
id: PATO:0000636
name: wholly ventralized
namespace: quality
def: "A ventralized quality inhering in a bearer by virtue of the bearer's gross morphology containing only what are normally ventral structures." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "ventralized" RELATED []
is_a: PATO:0030003 ! ventralized

[Term]
id: PATO:0000638
name: apoptotic
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's consisting of blebbing of the nucleus and DNA fragmentation due to the cell undergoing a specific form of programmed cell death termed apoptosis." [PATOC:GVG]
subset: value_slim
xref: GO:0006915
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0000642
name: fused with
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's being merged with another entity." [PATOC:GVG]
subset: mpath_slim
subset: relational_slim
subset: value_slim
synonym: "coalesced" RELATED []
synonym: "fused" EXACT []
synonym: "fused to" EXACT []
synonym: "joined with" RELATED []
synonym: "merged with" RELATED []
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0000651 ! unfused from

[Term]
id: PATO:0000644
name: hyperplastic
namespace: quality
alt_id: PATO:0000943
def: "A increased size quality inhering in an organ or tissue by virtue of the bearer's exhibiting increased number of cells." [Wikipedia:http\://en.wikipedia.org/wiki/Hyperplastic]
subset: mpath_slim
subset: value_slim
synonym: "hyperplasia" EXACT []
synonym: "overdeveloped" RELATED []
is_a: PATO:0000586 ! increased size
relationship: is_opposite_of PATO:0000645 ! hypoplastic

[Term]
id: PATO:0000645
name: hypoplastic
namespace: quality
alt_id: PATO:0000942
def: "A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced number of cells within an organ or tissue." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "hypoplasia" EXACT []
synonym: "underdeveloped" RELATED []
is_a: PATO:0000587 ! decreased size
is_a: PATO:0002290 ! aplastic/hypoplastic
relationship: is_opposite_of PATO:0000644 ! hyperplastic

[Term]
id: PATO:0000646
name: malformed
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's being distorted during formation." [PATOC:MAH]
subset: mpath_slim
subset: value_slim
synonym: "malformation" NARROW []
is_a: PATO:0001617 ! deformed

[Term]
id: PATO:0000647
name: necrotic
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's undergoing unprogrammed cell death." [Wikipedia:http\://en.wikipedia.org/wiki/Necrotic]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0000651
name: unfused from
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's being no longer merged with another entity." [PATOC:nw]
subset: relational_slim
subset: value_slim
synonym: "unfused" EXACT []
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0000642 ! fused with

[Term]
id: PATO:0000763
name: paralysed
namespace: quality
def: "A behavioral quality inhering in a bearer by virtue of the bearer's being affected by loss of the ability to move a body part." [PATOC:GVG]
subset: value_slim
synonym: "palsy" NARROW []
is_a: PATO:0002076 ! movement behavioral quality

[Term]
id: PATO:0000911
name: decreased rate
namespace: quality
def: "A rate which is relatively low." [PATO:GVG]
subset: mpath_slim
subset: value_slim
synonym: "slow rate" EXACT []
is_a: PATO:0000161 ! rate
is_a: PATO:0002302 ! decreased process quality
intersection_of: PATO:0000161 ! rate
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000912 ! increased rate

[Term]
id: PATO:0000912
name: increased rate
namespace: quality
def: "A rate which is relatively high." [PATO:GVG]
subset: mpath_slim
subset: value_slim
synonym: "fast rate" EXACT []
synonym: "high rate" EXACT []
is_a: PATO:0000161 ! rate
is_a: PATO:0002304 ! increased process quality
intersection_of: PATO:0000161 ! rate
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000911 ! decreased rate

[Term]
id: PATO:0000915
name: thickness
namespace: quality
def: "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." [WordNet:WordNet]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0001708 ! 1-D extent

[Term]
id: PATO:0000918
name: volume
namespace: quality
def: "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." [PATOC:GVG]
subset: attribute_slim
subset: mpath_slim
subset: scalar_slim
is_a: PATO:0001710 ! 3-D extent

[Term]
id: PATO:0000921
name: width
namespace: quality
def: "A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite." [PATOC:GVG]
subset: attribute_slim
subset: scalar_slim
synonym: "breadth" RELATED []
is_a: PATO:0001708 ! 1-D extent

[Term]
id: PATO:0000936
name: truncated
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's terminating abruptly by having or as if having an end or point cut off." [thefreedictionary.com:thefreedictionary.com]
subset: value_slim
synonym: "truncate" EXACT []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0000937
name: disorganized
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's lacking organisation." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0002264 ! organization quality
disjoint_from: PATO:0000938 ! organized
relationship: is_opposite_of PATO:0000938 ! organized

[Term]
id: PATO:0000938
name: organized
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's exhibiting organisation." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0002264 ! organization quality
relationship: is_opposite_of PATO:0000937 ! disorganized

[Term]
id: PATO:0000947
name: elliptic
namespace: quality
def: "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "ellipse-shaped" EXACT []
synonym: "ellipsoid" EXACT []
synonym: "elliptical" EXACT []
synonym: "oval" RELATED []
synonym: "ovoid" RELATED []
is_a: PATO:0002318 ! superelliptic

[Term]
id: PATO:0000967
name: undulate
namespace: quality
alt_id: PATO:0001610
alt_id: PATO:0001939
def: "A shape quality inhering in a bearer by virtue of the bearer's having a sinuate margin and rippled surface." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "rippled" RELATED []
synonym: "sinuate" RELATED []
synonym: "undulated" EXACT []
synonym: "undulating" EXACT []
synonym: "waved" EXACT []
synonym: "wavy" EXACT []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001018
name: physical quality
namespace: quality
alt_id: PATO:0002079
def: "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." [PATOC:GVG]
subset: attribute_slim
synonym: "relational physical quality" EXACT []
xref: Wikipedia:Physical_property
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001052
name: obtuse angle to
namespace: quality
def: "An angle which is between 90 degrees and 180 degrees to another entity." [thesaurus.maths:thesaurus.maths]
subset: relational_slim
subset: value_slim
is_a: PATO:0002326 ! angle

[Term]
id: PATO:0001154
name: elongated
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's length being notably higher than its width." [WordNet:WordNet]
subset: value_slim
is_a: PATO:0000052 ! shape
relationship: is_opposite_of PATO:0002364 ! shortened

[Term]
id: PATO:0001201
name: Y-shaped
namespace: quality
def: "A concave 3-D shape quality inhering in a bearer by virtue of the bearer's being shaped in the form of the letter Y." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
is_a: PATO:0001890 ! tripartite

[Term]
id: PATO:0001236
name: process quality
namespace: quality
alt_id: PATO:0001239
alt_id: PATO:0001240
def: "A quality which inheres in an process." [PATOC:GVG]
comment: See comments of relational quality of a physical entity.
synonym: "quality of a process" EXACT []
synonym: "quality of occurrent" EXACT []
synonym: "quality of process" EXACT []
synonym: "relational quality of occurrent" EXACT []
is_a: PATO:0000001 ! quality

[Term]
id: PATO:0001241
name: physical object quality
namespace: quality
alt_id: PATO:0001237
alt_id: PATO:0001238
def: "A quality which inheres in a continuant." [PATOC:GVG]
comment: Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles.
synonym: "monadic quality of a continuant" EXACT []
synonym: "monadic quality of an object" NARROW []
synonym: "monadic quality of continuant" NARROW []
synonym: "multiply inhering quality of a physical entity" EXACT []
synonym: "quality of a continuant" EXACT []
synonym: "quality of a single physical entity" EXACT []
synonym: "quality of an object" EXACT []
synonym: "quality of continuant" EXACT []
xref: snap:Quality
is_a: PATO:0000001 ! quality

[Term]
id: PATO:0001291
name: electromagnetic (EM) radiation quality
namespace: quality
def: "A physical quality that inheres in an bearer by virtue of how that bearer interacts with electromagnetic radiation." [Wikipedia:http\://en.wikipedia.org/wiki/Electromagnetic_radiation]
subset: attribute_slim
is_a: PATO:0001739 ! radiation quality

[Term]
id: PATO:0001300
name: optical quality
namespace: quality
def: "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001291 ! electromagnetic (EM) radiation quality

[Term]
id: PATO:0001303
name: variability
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's disposition to varying or changing." [Dictionary:http\://dictionary.reference.com/]
subset: attribute_slim
synonym: "variability of a physical quality" RELATED []
is_a: PATO:0001236 ! process quality

[Term]
id: PATO:0001323
name: area
namespace: quality
def: "A 2-D extent quality inhering in a bearer by virtue of the bearer's two dimensional extent." [Wikipedia:http\://en.wikipedia.org/wiki/Area]
subset: attribute_slim
subset: mpath_slim
subset: scalar_slim
is_a: PATO:0001709 ! 2-D extent

[Term]
id: PATO:0001334
name: diameter
namespace: quality
def: "A length quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary." [Wikipedia:http\://en.wikipedia.org/wiki/Diameter]
subset: attribute_slim
subset: mpath_slim
subset: scalar_slim
is_a: PATO:0000122 ! length

[Term]
id: PATO:0001355
name: convex
namespace: quality
def: "A shape quality that obtains by virtue of the bearer having inward facing edges; having a surface or boundary that curves or bulges outward, as the exterior of a sphere." [PATOC:GVG]
subset: cell_quality
subset: value_slim
is_a: PATO:0002005 ! concavity
relationship: is_opposite_of PATO:0001857 ! concave

[Term]
id: PATO:0001396
name: cellular quality
namespace: quality
def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG]
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001397
name: cellular potency
namespace: quality
def: "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." [PATOC:GVG]
subset: attribute_slim
subset: disposition_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001402
name: multipotent
namespace: quality
def: "A cellular potency that is the capacity to form multiple differentiated cell types." [Wikipedia:http\://en.wikipedia.org/wiki/Multipotent]
subset: cell_quality
subset: disposition_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency

[Term]
id: PATO:0001404
name: nucleate quality
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001405
name: anucleate
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001404 ! nucleate quality

[Term]
id: PATO:0001422
name: dead
namespace: quality
def: "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000169 ! viability

[Term]
id: PATO:0001431
name: adhesivity
namespace: quality
def: "An emergent molecular quality that arises by virtue of the bearer's disposition to exhibit molecular attraction to another entity in contact." [PATOC:GVG]
comment: The definition is general enough to cover adhesion arising from different kinds of chemical bonding/forces, although for PATO this term will most commonly used for cellular adhesion. See also GO:0031589 "cell-substrate adhesion".
subset: attribute_slim
subset: disposition_slim
subset: relational_slim
synonym: "adhesiveness" EXACT []
synonym: "stickiness" RELATED []
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0001433
name: growth quality of occurrent
namespace: quality
alt_id: PATO:0001489
def: "A quality of a single process which describes the growth of an organism, structure, or group of organisms." [PATOC:MAH]
subset: attribute_slim
synonym: "growth quality of a process" RELATED []
synonym: "growth timing quality" RELATED []
is_a: PATO:0001236 ! process quality

[Term]
id: PATO:0001450
name: edematous
namespace: quality
def: "A structural quality which is held by a bearer when the latter exhibits an excessive accumulation of extracellular fluid." [thefreedictionary.com:thefreedictionary.com]
subset: mpath_slim
subset: value_slim
synonym: "edema" NARROW []
synonym: "edemic" EXACT []
synonym: "oedema" NARROW []
synonym: "oedematous" EXACT []
synonym: "oedemic" EXACT []
is_a: PATO:0000025 ! composition

[Term]
id: PATO:0001468
name: curved dorsal
namespace: quality
def: "A curvature quality inhering in a bearer by virtue of the bearer's being curved towards the back or upper surface of an organism." [PATOC:GVG]
subset: value_slim
synonym: "curved posterior (human torso)" EXACT []
synonym: "curved superior (human head)" EXACT []
is_a: PATO:0000406 ! curved

[Term]
id: PATO:0001469
name: curved ventral
namespace: quality
def: "A curvature quality inhering in a bearer by virtue of the bearer's being curved towards the abdomen of an organism." [PATOC:GVG]
subset: value_slim
synonym: "curved anterior (human torso)" EXACT []
synonym: "curved inferior (human head)" EXACT []
is_a: PATO:0000406 ! curved

[Term]
id: PATO:0001473
name: duplicated
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's being present in two copies." [Dictionary.com:Dictionary.com]
subset: mpath_slim
subset: value_slim
synonym: "doubled" EXACT []
is_a: PATO:0000470 ! increased amount

[Term]
id: PATO:0001475
name: increased position
namespace: quality
def: "A position which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "high position" RELATED []
is_a: PATO:0000140 ! position
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000140 ! position
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001476 ! decreased position

[Term]
id: PATO:0001476
name: decreased position
namespace: quality
def: "A positional which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "low position" RELATED []
is_a: PATO:0000140 ! position
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000140 ! position
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001475 ! increased position

[Term]
id: PATO:0001483
name: aplastic
namespace: quality
def: "Absence of an organ, tissue or cell due to failure to develop from a primordium or precursor cell." [PATOC:GVG, PATOC:PortlandMeetingFeb2015]
comment: With aplasia, the primordium or precursor develops, but does not proceed in its development to a mature structure
subset: mpath_slim
subset: value_slim
synonym: "aplasia" EXACT []
synonym: "undeveloped" EXACT []
is_a: PATO:0002290 ! aplastic/hypoplastic
is_a: PATO:0002291 ! agenesis
intersection_of: PATO:0002290 ! aplastic/hypoplastic
intersection_of: PATO:0002291 ! agenesis

[Term]
id: PATO:0001485
name: condensed
namespace: quality
alt_id: PATO:0001840
def: "A structural quality inhering in a bearer by virtue of the bearer's being thicker or more closely packed together; pressed tightly together." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "compact" BROAD []
synonym: "compressed" EXACT []
synonym: "dense" RELATED []
synonym: "squashed" EXACT []
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0002452 ! decondensed

[Term]
id: PATO:0001490
name: heterochronic growth
namespace: quality
def: "A growth quality of a process inhering in an organism, structure, or group of organisms by virtue of the bearer's reduced or increased growth." [PATOC:MAH]
subset: value_slim
is_a: PATO:0001433 ! growth quality of occurrent

[Term]
id: PATO:0001499
name: spherical
namespace: quality
alt_id: PATO:0000408
def: "A spheroid quality inhering in a bearer by virtue of the bearer's resembling a ball (a sphere whose equatorial diameter is equal to the polar diameter)." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "globular" EXACT []
synonym: "rotund" RELATED []
is_a: PATO:0001865 ! spheroid
relationship: has_cross_section PATO:0000411 ! circular

[Term]
id: PATO:0001501
name: immature
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster]
subset: value_slim
synonym: "underdeveloped" RELATED []
is_a: PATO:0000261 ! maturity
relationship: is_opposite_of PATO:0001701 ! mature

[Term]
id: PATO:0001502
name: complexity
namespace: quality
def: "A monadic quality of continuant inhering in a bearer by virtue of the bearer's being intricate and compounded." [WordNet:WordNet]
comment: TODO: obsolete this.
subset: attribute_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0001503
name: simple
namespace: quality
def: "A complexity quality in a bearer by virtue of the bearer's having few parts or being complicated or compound." [WordNet:WordNet]
subset: mpath_slim
subset: value_slim
is_a: PATO:0001502 ! complexity

[Term]
id: PATO:0001505
name: separated from
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's not being in contact with another entity, or of no longer being connected or joined with another entity." [WordNet:WordNet]
subset: relational_slim
subset: value_slim
synonym: "discontiguous" RELATED []
synonym: "divided_from" RELATED []
synonym: "splitted from" RELATED []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0001507
name: disrupted
namespace: quality
def: "A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000057 ! occurrence

[Term]
id: PATO:0001542
name: delayed phase
namespace: quality
def: "A phase which starts later than natural start point." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000083 ! phase

[Term]
id: PATO:0001555
name: has number of
namespace: quality
def: "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." [PATOC:CJM]
subset: attribute_slim
subset: relational_slim
synonym: "cardinality" RELATED []
synonym: "extra or missing physical or functional parts" EXACT []
synonym: "has or lacks parts of type" EXACT []
synonym: "mereological quality" EXACT []
synonym: "number" RELATED []
synonym: "number of" EXACT []
xref: OBO_REL:has_part
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001558
name: lacking processual parts
namespace: quality
def: "A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity." [PATOC:GVG]
subset: relational_slim
subset: value_slim
is_a: PATO:0001564 ! extra or missing processual parts

[Term]
id: PATO:0001562
name: decreased mass
namespace: quality
alt_id: PATO:0000579
def: "A mass which is lower than normal or average." [PATO:GVG]
subset: value_slim
synonym: "low mass" EXACT []
synonym: "small mass" EXACT []
is_a: PATO:0000125 ! mass
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000125 ! mass
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001563 ! increased mass

[Term]
id: PATO:0001563
name: increased mass
namespace: quality
alt_id: PATO:0000578
def: "A mass which is higher than normal or average." [PATO:GVG]
subset: value_slim
synonym: "high mass" EXACT []
synonym: "large mass" EXACT []
is_a: PATO:0000125 ! mass
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000125 ! mass
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001562 ! decreased mass

[Term]
id: PATO:0001564
name: extra or missing processual parts
namespace: quality
def: "A quality of a process inhering in a bearer by virtue of the bearer's processual parts." [PATOC:GVG]
subset: relational_slim
is_a: PATO:0001236 ! process quality

[Term]
id: PATO:0001566
name: distributed
namespace: quality
alt_id: PATO:0001513
def: "A spatial pattern inhering in a bearer by virtue of the bearer's being spread out or scattered about or divided up." [WordNet:WordNet]
subset: mpath_slim
subset: value_slim
synonym: "diffuse" EXACT []
synonym: "scattered" EXACT []
is_a: PATO:0000060 ! spatial pattern
relationship: is_opposite_of PATO:0001567 ! undistributed

[Term]
id: PATO:0001567
name: undistributed
namespace: quality
def: "A spatial pattern inhering in a bearer by virtue of the bearer's not being spread out or scattered about or divided up." [WordNet:WordNet]
subset: value_slim
is_a: PATO:0000060 ! spatial pattern
relationship: is_opposite_of PATO:0001566 ! distributed

[Term]
id: PATO:0001571
name: dilated
namespace: quality
def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions." [WordNet:WordNet]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000586 ! increased size

[Term]
id: PATO:0001591
name: curvature
namespace: quality
def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001592
name: increased curvature
namespace: quality
def: "A curvature which is relatively high." [PATO:GVG]
subset: value_slim
is_a: PATO:0000406 ! curved
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000406 ! curved
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001593 ! decreased curvature

[Term]
id: PATO:0001593
name: decreased curvature
namespace: quality
def: "A curvature which is relatively low." [PATO:GVG]
subset: value_slim
is_a: PATO:0000406 ! curved
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000406 ! curved
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001592 ! increased curvature

[Term]
id: PATO:0001598
name: protruding
namespace: quality
alt_id: PATO:0001644
def: "A quality inhering in a bearer by virtue of the bearer's extending out above or beyond a surface or boundary." [WordNet:WordNet]
subset: value_slim
synonym: "protruding" EXACT []
synonym: "relational protruding quality" EXACT []
is_a: PATO:0000140 ! position

[Term]
id: PATO:0001617
name: deformed
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's being distorted in form." [thefreedictionary.com:thefreedictionary.com]
subset: value_slim
synonym: "disfigured" RELATED []
synonym: "distorted" RELATED []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0001645
name: protruding into
namespace: quality
def: "A quality inhering into a bearer by virtue of the bearer's extending out above or beyond its surface or boundary into the surface or boundary of another entity." [PATOC:nc]
subset: relational_slim
subset: value_slim
is_a: PATO:0001598 ! protruding

[Term]
id: PATO:0001646
name: protruding out of
namespace: quality
def: "A quality inhering into a bearer by virtue of the bearer's extending out above or beyond its surface or boundary and outwards in relation to the physical space occupied by another entity." [PATOC:nc]
subset: relational_slim
subset: value_slim
synonym: "exits through" RELATED []
synonym: "exposed" RELATED []
synonym: "extruding from" EXACT []
is_a: PATO:0001598 ! protruding

[Term]
id: PATO:0001649
name: curved lateral
namespace: quality
def: "A curvature quality inhering in a bearer by virtue of the bearer's being curved towards the side." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000406 ! curved

[Term]
id: PATO:0001652
name: alignment
namespace: quality
def: "A spatial quality inhering in a bearer by virtue of the bearer's spatial positioning with respect to an additional entity." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
is_a: PATO:0000140 ! position
relationship: has_part PATO:0000133 ! orientation

[Term]
id: PATO:0001653
name: aligned with
namespace: quality
def: "An alignment quality inhering in a bearer by virtue of the bearer's being in a proper spatial positioning with respect to an additional entity." [PATO:GVG]
subset: relational_slim
subset: value_slim
synonym: "aligned" EXACT []
synonym: "aligned to" RELATED []
is_a: PATO:0001652 ! alignment
relationship: is_opposite_of PATO:0001654 ! misaligned with

[Term]
id: PATO:0001654
name: misaligned with
namespace: quality
def: "An alignment quality inhering in a bearer by virtue of the bearer's being in a improper spatial positioning with respect to an additional entity." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "misaligned" EXACT []
synonym: "unaligned with" EXACT []
is_a: PATO:0001652 ! alignment
relationship: is_opposite_of PATO:0001653 ! aligned with

[Term]
id: PATO:0001671
name: increased distribution
namespace: quality
def: "A distribution which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "high distribution" EXACT []
is_a: PATO:0001475 ! increased position
is_a: PATO:0001566 ! distributed
intersection_of: PATO:0001566 ! distributed
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001672 ! decreased distribution

[Term]
id: PATO:0001672
name: decreased distribution
namespace: quality
def: "A distribution which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "low distribution" EXACT []
is_a: PATO:0001476 ! decreased position
is_a: PATO:0001566 ! distributed
intersection_of: PATO:0001566 ! distributed
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001671 ! increased distribution

[Term]
id: PATO:0001701
name: mature
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's exhibiting complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster]
subset: value_slim
is_a: PATO:0000261 ! maturity
relationship: is_opposite_of PATO:0001501 ! immature

[Term]
id: PATO:0001708
name: 1-D extent
namespace: quality
def: "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." [PATOC:GVG]
subset: attribute_slim
synonym: "1-D size" EXACT []
is_a: PATO:0000117 ! size

[Term]
id: PATO:0001709
name: 2-D extent
namespace: quality
def: "A size quality inhering in an bearer by virtue of the bearer's extension in two dimensions." [PATOC:GVG]
subset: attribute_slim
synonym: "2-D size" EXACT []
is_a: PATO:0000117 ! size

[Term]
id: PATO:0001710
name: 3-D extent
namespace: quality
def: "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions." [PATOC:GVG]
subset: attribute_slim
synonym: "3D size" EXACT []
is_a: PATO:0000117 ! size

[Term]
id: PATO:0001714
name: increased diameter
namespace: quality
def: "A diameter which is relatively large." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000573 ! increased length
is_a: PATO:0001334 ! diameter
intersection_of: PATO:0001334 ! diameter
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001715 ! decreased diameter

[Term]
id: PATO:0001715
name: decreased diameter
namespace: quality
def: "A diameter which is relatively small." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000574 ! decreased length
is_a: PATO:0001334 ! diameter
intersection_of: PATO:0001334 ! diameter
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001714 ! increased diameter

[Term]
id: PATO:0001738
name: dissociated from
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's lacking physically interaction with another entity." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "dissociated" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0001739
name: radiation quality
namespace: quality
def: "A quality that inheres in an bearer by virtue of how that bearer interacts with radiation." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0001749
name: paedomorphic growth
namespace: quality
def: "A heterochronic growth quality inhering in an organism, structure, or group of organisms by virtue of the bearer's reduced growth." [PATOC:mh]
subset: value_slim
synonym: "hypoplastic growth" EXACT []
synonym: "pedomorphic growth" EXACT []
is_a: PATO:0001490 ! heterochronic growth
relationship: is_opposite_of PATO:0001752 ! peramorphic growth

[Term]
id: PATO:0001752
name: peramorphic growth
namespace: quality
def: "A heterochronic growth quality inhering in an organism, structure, or group of organisms by virtue of the bearer's increased growth." [PATOC:mh]
subset: attribute_slim
synonym: "hyperplastic growth" EXACT []
is_a: PATO:0001490 ! heterochronic growth
relationship: is_opposite_of PATO:0001749 ! paedomorphic growth

[Term]
id: PATO:0001755
name: hypermorphic growth
namespace: quality
def: "A peramorphic growth quality which is due to a delayed offset." [PATOC:mh]
subset: value_slim
is_a: PATO:0001752 ! peramorphic growth

[Term]
id: PATO:0001770
name: semi-viable
namespace: quality
def: "A viability quality inhering in a population by virtue of some of it's members' ability to survive." [PATOC:CVC]
subset: disposition_slim
subset: value_slim
is_a: PATO:0000169 ! viability

[Term]
id: PATO:0001772
name: surrounding
namespace: quality
def: "A spatial quality inhering in a bearer by virtue of the bearer's being extended on all sides of another entity simultaneously." [thefreedictionary.com:thefreedictionary.com]
comment: Nedd to add reciprocal of relationship to 'surrounded by' PATO:0005016.
subset: relational_slim
subset: value_slim
synonym: "encircling" EXACT []
synonym: "enclosing" EXACT []
synonym: "wrapping" EXACT []
is_a: PATO:0000140 ! position

[Term]
id: PATO:0001784
name: bifurcated
namespace: quality
alt_id: PATO:0001572
def: "A branched quality inhering in a bearer by virtue of the bearer's being divided into two branches." [thefreedictionary.com:thefreedictionary.com]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "bifid" EXACT []
synonym: "forked" RELATED []
is_a: PATO:0000402 ! branched
is_a: PATO:0001786 ! split

[Term]
id: PATO:0001786
name: split
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being divided or broken up into parts or divisions." [die.net:die.net]
subset: mpath_slim
subset: value_slim
synonym: "clefted" EXACT []
synonym: "divided" RELATED []
synonym: "forked" RELATED []
synonym: "septate" NARROW []
synonym: "subdivided" RELATED []
is_a: PATO:0000052 ! shape
disjoint_from: PATO:0002034 ! undivided

[Term]
id: PATO:0001794
name: coiling
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." [Online_Dictionary:Online_Dictionary]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001795
name: increased coiling
namespace: quality
def: "A coiling which is relatively high." [PATOC:GVG]
subset: cell_quality
subset: value_slim
synonym: "high coiling" EXACT []
is_a: PATO:0000404 ! coiled
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000404 ! coiled
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001796 ! decreased coiling

[Term]
id: PATO:0001796
name: decreased coiling
namespace: quality
def: "A coiling which is relatively low." [PATOC:GVG]
subset: cell_quality
subset: value_slim
synonym: "low coiling" EXACT []
is_a: PATO:0000404 ! coiled
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000404 ! coiled
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001795 ! increased coiling

[Term]
id: PATO:0001798
name: kinked
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's having multiple angles in its length." [thefreedictionary.com:thefreedictionary.com]
subset: cell_quality
subset: value_slim
synonym: "tightly curled" RELATED []
synonym: "twisted" RELATED []
is_a: PATO:0000617 ! bent

[Term]
id: PATO:0001799
name: ruffled
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's exhibiting disturbance of its smoothness or regularity." [.thefreedictionary.com:.thefreedictionary.com]
subset: cell_quality
subset: value_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001802
name: loose
namespace: quality
def: "A pattern quality inhering in a bearer by virtue of the bearer's not being compact or dense in arrangement." [answers.com:answers.com]
subset: value_slim
is_a: PATO:0000330 ! irregular spatial pattern

[Term]
id: PATO:0001847
name: constricted
namespace: quality
alt_id: PATO:0001837
def: "A structural quality inhering in a bearer by virtue of the bearer's being drawn together, compressed or squeezed physically." [WordNet:WordNet]
subset: value_slim
synonym: "stenosis" EXACT []
synonym: "stenotic" EXACT []
synonym: "stricture" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0001857
name: concave
namespace: quality
def: "A shape quality in a bearer by virtue of the bearer's curving inward." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
is_a: PATO:0002005 ! concavity
relationship: is_opposite_of PATO:0001355 ! convex

[Term]
id: PATO:0001861
name: fasciculated
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's forming a bundle of aligned anatomical fibers, as of muscle or nerve." [answers.com:answers.com]
subset: mpath_slim
subset: value_slim
synonym: "fascicled" EXACT []
is_a: PATO:0002013 ! fasciculation
disjoint_from: PATO:0001959 ! defasciculated
relationship: is_opposite_of PATO:0001959 ! defasciculated

[Term]
id: PATO:0001865
name: spheroid
namespace: quality
alt_id: PATO:0001864
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's having a quadric surface in three dimensions obtained by rotating an ellipse about one of its principal axes. Includes spheres and oblate/prolate spheroids." [Wikipedia:http\://en.wikipedia.org/wiki/Spheroid]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "sphericality" RELATED []
is_a: PATO:0002007 ! convex 3-D shape

[Term]
id: PATO:0001873
name: cylindrical
namespace: quality
alt_id: PATO:0001203
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." [PATOC:MAH]
subset: cell_quality
subset: value_slim
synonym: "rod-like" EXACT []
synonym: "rod-shaped" EXACT []
synonym: "tubulate" NARROW []
is_a: PATO:0002007 ! convex 3-D shape
relationship: has_cross_section PATO:0000411 ! circular

[Term]
id: PATO:0001875
name: triangular
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's having three angles." [wordreference:wordreference]
subset: cell_quality
subset: value_slim
synonym: "delta shaped" RELATED []
synonym: "deltoid" EXACT []
synonym: "triangle" RELATED []
synonym: "triangle-shaped" RELATED []
is_a: PATO:0002006 ! 2-D shape

[Term]
id: PATO:0001879
name: U-shaped
namespace: quality
def: "A concave 3-D shape quality inhering in a bearer by virtue of the bearer's being shaped in the form of the letter U." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
synonym: "horseshoe" NARROW []
synonym: "horseshoe shaped" EXACT []
is_a: PATO:0002008 ! concave 3-D shape

[Term]
id: PATO:0001890
name: tripartite
namespace: quality
def: "A concave 3-D shape quality inhering in a bearer by virtue of the bearer's being divided into three branches." [InfoVisual:InfoVisual]
subset: cell_quality
subset: value_slim
synonym: "trifurcate" EXACT []
is_a: PATO:0000402 ! branched
is_a: PATO:0002008 ! concave 3-D shape

[Term]
id: PATO:0001894
name: phenotypic sex
namespace: quality
def: "An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics." []
subset: attribute_slim
is_a: PATO:0000047 ! biological sex

[Term]
id: PATO:0001905
name: has normal numbers of parts of type
namespace: quality
def: "The bearer of this quality has_part = n, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." [PATOC:CJM]
subset: relational_slim
synonym: "having physical part" EXACT []
is_a: PATO:0001555 ! has number of

[Term]
id: PATO:0001920
name: mislocalised ventrally
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being positioned towards the abdomen of an organism." [PATOC:mb]
subset: value_slim
is_a: PATO:0000628 ! mislocalised

[Term]
id: PATO:0001921
name: mislocalised anteriorly
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being positioned towards the front of an organism." [PATOC:mb]
subset: value_slim
is_a: PATO:0000628 ! mislocalised

[Term]
id: PATO:0001922
name: mislocalised posteriorly
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being positioned towards the rear of an organism." [PATOC:mb]
subset: value_slim
is_a: PATO:0000628 ! mislocalised

[Term]
id: PATO:0001924
name: mislocalised medially
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being positioned towards the middle of an organism." [PATOC:mb]
subset: value_slim
is_a: PATO:0000628 ! mislocalised

[Term]
id: PATO:0001928
name: blistered
namespace: quality
def: "A texture quality inhering in a bearer by virtue of a local accumulation of fluid underneath the surface of the bearer." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "blistering" NARROW []
is_a: PATO:0000150 ! texture

[Term]
id: PATO:0001929
name: variability of shape
namespace: quality
def: "A variability quality inhering in a bearer by virtue of whether the bearer exhibits shape variation or change." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001303 ! variability
relationship: towards PATO:0000052 ! shape

[Term]
id: PATO:0001930
name: variant shape
namespace: quality
def: "A quality inhering in a bearer by virtue the bearer's having or exhibiting variation its shape." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001929 ! variability of shape
relationship: is_opposite_of PATO:0001931 ! invariant shape

[Term]
id: PATO:0001931
name: invariant shape
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's lacking or not exhibiting variation of shape." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001929 ! variability of shape
relationship: is_opposite_of PATO:0001930 ! variant shape

[Term]
id: PATO:0001935
name: obtuse
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being roundish, a little inclining to be oblong." [ISBN:0881923214]
subset: value_slim
synonym: "roundish" EXACT []
is_a: PATO:0000411 ! circular

[Term]
id: PATO:0001956
name: variability of size
namespace: quality
def: "A variability quality inhering in a bearer by virtue of whether the bearer exhibits size variation or change." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001303 ! variability
relationship: towards PATO:0000117 ! size

[Term]
id: PATO:0001957
name: decreased variability of size
namespace: quality
def: "A variability of size which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "low variability of size" EXACT []
is_a: PATO:0001956 ! variability of size
is_a: PATO:0002302 ! decreased process quality
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0001956 ! variability of size
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001958 ! increased variability of size

[Term]
id: PATO:0001958
name: increased variability of size
namespace: quality
def: "A variability of size which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "high variability of size" EXACT []
is_a: PATO:0001956 ! variability of size
is_a: PATO:0002304 ! increased process quality
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0001956 ! variability of size
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0001957 ! decreased variability of size

[Term]
id: PATO:0001959
name: defasciculated
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's in which bundles of aligned anatomical fibers have become separated." [PATOC:mw]
subset: value_slim
is_a: PATO:0002013 ! fasciculation
relationship: is_opposite_of PATO:0001861 ! fasciculated

[Term]
id: PATO:0001995
name: organismal quality
namespace: quality
def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM]
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001997
name: decreased amount
namespace: quality
alt_id: PATO:0000419
alt_id: PATO:0000468
def: "An amount which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "decreased" RELATED []
synonym: "decreased number" EXACT []
synonym: "present in fewer numbers in organism" EXACT []
synonym: "reduced" RELATED []
synonym: "subnumerary" RELATED []
is_a: PATO:0000467 ! present
is_a: PATO:0002301 ! decreased quality
intersection_of: PATO:0000070 ! amount
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0000470 ! increased amount

[Term]
id: PATO:0001999
name: lacks parts or has fewer parts of type
namespace: quality
def: "The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type." [PATOC:CJM]
subset: relational_slim
synonym: "loss of" EXACT []
is_a: PATO:0002083 ! altered number of

[Term]
id: PATO:0002000
name: lacks all parts of type
namespace: quality
alt_id: PATO:0001557
def: "A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity." [PATOC:CJM]
comment: Example: [E=organism Q=lacks_all_parts_of_type E2=Wing] - applies to an organism. A relational quality in which the bearer entity has no parts of the specified type. The bearer of this quality has_part = 0 of the indicated entity type, where a comparable organism usually has at least 1 part of the same type. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e lacks all parts of type X at time t, then there exists no instances x of X at t such that x part_of e that has no wings, where wings are normally present in that organism type. In OWL this is equivalent to a restriction on the OBO_REL:has_part relation with cardinality=0, i.e has_part 0 E2.
subset: relational_slim
synonym: "lacks all physical parts of type" EXACT []
xref: OBO_REL:lacks_part
is_a: PATO:0001999 ! lacks parts or has fewer parts of type

[Term]
id: PATO:0002001
name: has fewer parts of type
namespace: quality
alt_id: PATO:0001569
def: "The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly." [PATOC:CJM]
comment: Example: [E=hand Q=has_fewer_parts_of_type E2=digit] - applies to an organism that has no less fingers than is normal for organisms of that type.
subset: relational_slim
synonym: "decreased number of" EXACT []
synonym: "has decreased number of" EXACT []
synonym: "has fewer physical parts of type" EXACT []
is_a: PATO:0001999 ! lacks parts or has fewer parts of type
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0001999 ! lacks parts or has fewer parts of type
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002002 ! has extra parts of type

[Term]
id: PATO:0002002
name: has extra parts of type
namespace: quality
alt_id: PATO:0001560
def: "The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." [PATOC:CJM]
comment: In polydactyly, the bearer of the quality is the hand, and the entity type being counted is 'finger'. In EQ syntax, E=hand, Q=<this> E2=finger.
subset: relational_slim
synonym: "has extra parts of" EXACT []
synonym: "has increased number of" EXACT []
synonym: "having extra physical parts" EXACT []
synonym: "having supernumerary physical parts" EXACT []
synonym: "increased number of" EXACT []
is_a: PATO:0002083 ! altered number of
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0002083 ! altered number of
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002001 ! has fewer parts of type

[Term]
id: PATO:0002005
name: concavity
namespace: quality
def: "Surface shape that refers to the inward or outward curvature of the surface." [PATOC:MAH]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002006
name: 2-D shape
namespace: quality
def: "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." [PATOC:CJM]
subset: attribute_slim
synonym: "2-D projection" RELATED []
synonym: "cross-sectional" RELATED []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002007
name: convex 3-D shape
namespace: quality
def: "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." [PATOC:CJM]
comment: Use this term or an is_a child of this term when the entire shape of the object is known.
subset: attribute_slim
xref: Image:http\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png
is_a: PATO:0002266 ! 3-D shape
relationship: has_cross_section PATO:0002006 ! 2-D shape
relationship: is_opposite_of PATO:0002008 ! concave 3-D shape

[Term]
id: PATO:0002008
name: concave 3-D shape
namespace: quality
def: "A complete three dimensional shape in which there is a line connecting pair of points on the object that lies outside the object. Or: a shape with cavities. Contrast: concave." [PATOC:CJM]
subset: attribute_slim
xref: Image:http\://en.wikipedia.org/wiki/Image\:Convex_polygon_illustration2.png
is_a: PATO:0002266 ! 3-D shape
relationship: has_part PATO:0001857 ! concave
relationship: is_opposite_of PATO:0002007 ! convex 3-D shape

[Term]
id: PATO:0002009
name: branchiness
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:MAH]
subset: attribute_slim
subset: cell_quality
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002011
name: neoplastic
namespace: quality
def: "A structural quality which is held by a bearer when the latter's disposition the presence of abnormally proliferating masses of cells." [PATOC:MAH]
subset: disposition_slim
subset: mpath_slim
subset: value_slim
synonym: "tumorous" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0002013
name: fasciculation
namespace: quality
def: "A structural quality inhering in a bearer by virtue of whether the bearer forms a bundle of anatomical fibers, as of muscle or nerve." [answers.com:http\://www.answers.com/]
subset: attribute_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0002019
name: aplastic growth
namespace: quality
def: "A growth quality of occurrent in which the growth of an organism, structure or group of organisms does not occur." [PATOC:MAH]
synonym: "agenesis" NARROW []
is_a: PATO:0001433 ! growth quality of occurrent

[Term]
id: PATO:0002021
name: conical
namespace: quality
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's resembling a cone (a 3-D shape with a round cross section that tapers)." [Wikipedia:http\://en.wikipedia.org/wiki/Cone_(geometry)]
subset: value_slim
synonym: "cone-shaped" EXACT []
xref: Image:http\://upload.wikimedia.org/wikipedia/commons/d/d2/Cone_3d.png
is_a: PATO:0002007 ! convex 3-D shape

[Term]
id: PATO:0002034
name: undivided
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being unseparated into parts or divisions." [PATOC:GVG]
subset: value_slim
synonym: "unseparated" RELATED []
is_a: PATO:0000052 ! shape
created_by: george
creation_date: 2009-01-27T11:53:46Z

[Term]
id: PATO:0002037
name: degeneration
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer exhibiting deterioration of its structure." [PATOC:GVG]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0000141 ! structure
created_by: george
creation_date: 2009-02-03T11:13:19Z

[Term]
id: PATO:0002050
name: normal amount
namespace: quality
def: "An amount which normal." [PATOC:GVG]
synonym: "present in normal numbers in organism" EXACT []
is_a: PATO:0000467 ! present
relationship: reciprocal_of PATO:0001905 ! has normal numbers of parts of type
created_by: george
creation_date: 2009-03-20T11:16:22Z

[Term]
id: PATO:0002051
name: increased occurrence
namespace: quality
def: "An occurrence which is relatively high." [PATOC:GVG]
synonym: "increased incidence" EXACT []
is_a: PATO:0000057 ! occurrence
is_a: PATO:0002304 ! increased process quality
intersection_of: PATO:0000057 ! occurrence
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002052 ! decreased occurrence
created_by: George Gkoutos
creation_date: 2009-03-26T11:10:11Z

[Term]
id: PATO:0002052
name: decreased occurrence
namespace: quality
def: "An occurrence which is relatively low." [PATOC:GVG]
synonym: "decreased incidence" EXACT []
is_a: PATO:0000057 ! occurrence
is_a: PATO:0002302 ! decreased process quality
intersection_of: PATO:0000057 ! occurrence
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002051 ! increased occurrence
created_by: George Gkoutos
creation_date: 2009-03-26T11:12:35Z

[Term]
id: PATO:0002053
name: dorso-ventrally flattened
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's being flattened along dorso-ventral axis." [PATOC:MSP]
subset: value_slim
is_a: PATO:0002254 ! flattened
created_by: George Gkoutos
creation_date: 2009-03-26T03:02:38Z

[Term]
id: PATO:0002057
name: increased area
namespace: quality
def: "An area which is relatively high." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000586 ! increased size
is_a: PATO:0001323 ! area
intersection_of: PATO:0001323 ! area
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002058 ! decreased area
created_by: George Gkoutos
creation_date: 2009-03-30T04:11:43Z

[Term]
id: PATO:0002058
name: decreased area
namespace: quality
def: "An area which is relatively low." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000587 ! decreased size
is_a: PATO:0001323 ! area
intersection_of: PATO:0001323 ! area
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002057 ! increased area
created_by: George Gkoutos
creation_date: 2009-03-30T04:12:11Z

[Term]
id: PATO:0002062
name: physical quality of a process
namespace: quality
subset: attribute_slim
is_a: PATO:0001236 ! process quality
created_by: george
creation_date: 2009-06-05T09:16:46Z

[Term]
id: PATO:0002076
name: movement behavioral quality
namespace: quality
def: "A behavioral quality inhering in a bearer by virtue of the bearer's movement." [PATOC:GVG]
subset: attribute_slim
synonym: "movement behavioural quality" EXACT []
is_a: PATO:0000186 ! behavioral quality
created_by: George Gkoutos
creation_date: 2009-09-18T02:04:48Z

[Term]
id: PATO:0002083
name: altered number of
namespace: quality
def: "Having extra or fewer parts." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
is_a: PATO:0001555 ! has number of
created_by: George Gkoutos
creation_date: 2009-09-21T10:41:58Z

[Term]
id: PATO:0002099
name: differentiated
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of its stable specialization to a particular cell type." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency
relationship: is_opposite_of PATO:0002100 ! undifferentiated
created_by: george
creation_date: 2009-10-05T12:58:54Z

[Term]
id: PATO:0002100
name: undifferentiated
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of having not yet acquired a special structure of function." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency
relationship: is_opposite_of PATO:0002099 ! differentiated
created_by: george
creation_date: 2009-10-05T12:59:21Z

[Term]
id: PATO:0002105
name: hemorrhagic
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's exhibiting excessive discharge of blood from the blood vessels." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure
created_by: george
creation_date: 2009-10-05T01:55:53Z

[Term]
id: PATO:0002106
name: poorly differentiated
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of its lacking most of the cellular characteristics which would allow it to be fully differentiated." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0002099 ! differentiated
created_by: george
creation_date: 2009-10-05T02:53:43Z

[Term]
id: PATO:0002118
name: multiple
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's being present in more than two copies." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000470 ! increased amount
created_by: george
creation_date: 2009-10-06T03:28:38Z

[Term]
id: PATO:0002125
name: nodular
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's consisting a knot-like mass." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure
created_by: george
creation_date: 2009-10-06T04:40:06Z

[Term]
id: PATO:0002135
name: delayed closure
namespace: quality
def: "A duration quality of a process inhering in a bearer by virtue of the bearer's delay to complete the closure of the opening of an anatomical entity." [PATOC:GVG]
is_a: PATO:0000502 ! delayed
created_by: george
creation_date: 2009-10-26T01:03:17Z

[Term]
id: PATO:0002168
name: displaced to
namespace: quality
def: "An angular placement quality inhering in a bearer by virtue of the bearer being changed in position in relation to another entity." [PATOC:GVG]
subset: relational_slim
synonym: "mislocalised to" RELATED []
is_a: PATO:0000133 ! orientation
created_by: george
creation_date: 2010-01-14T04:45:18Z

[Term]
id: PATO:0002175
name: deviation
namespace: quality
def: "A spatial quality inhering in a bearer by virtue of the bearer's changed direction of position towards another entity." [PATO:GVG]
subset: attribute_slim
is_a: PATO:0000060 ! spatial pattern
created_by: George Gkoutos
creation_date: 2010-02-25T09:14:42Z

[Term]
id: PATO:0002177
name: deviation towards the medial side
namespace: quality
def: "A deviation quality inhering in a bearer by virtue of the bearer's changed direction of position towards the middle." [PATOC:GVG]
subset: value_slim
is_a: PATO:0002175 ! deviation
created_by: George Gkoutos
creation_date: 2010-02-25T09:16:56Z

[Term]
id: PATO:0002181
name: displaced
namespace: quality
def: "A positional quality inhering in a bearer by virtue the bearer's being changed in position." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000140 ! position
created_by: George Gkoutos
creation_date: 2010-03-01T02:56:33Z

[Term]
id: PATO:0002247
name: degree of pigmentation
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's having or lacking of substances produced by living organisms that have a color resulting from selective color absorption." [url:http\://en.wikipedia.org/wiki/Biological_pigment]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0000141 ! structure
relationship: correlates_with PATO:0000014 ! color
created_by: george
creation_date: 2010-08-09T04:14:00Z

[Term]
id: PATO:0002248
name: pigmented
namespace: quality
def: "A degree of pigmentation quality inhering in a bearer by virtue of the bearer's having substances produced by living organisms that have a color resulting from selective color absorption." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0002247 ! degree of pigmentation
disjoint_from: PATO:0002249 ! unpigmented
relationship: is_opposite_of PATO:0002249 ! unpigmented
created_by: george
creation_date: 2010-08-09T04:16:49Z

[Term]
id: PATO:0002249
name: unpigmented
namespace: quality
def: "A degree of pigmentation quality inhering in a bearer by virtue of the bearer's lacking substances produced by living organisms that have a color resulting from selective color absorption." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "depigmented" EXACT []
is_a: PATO:0002247 ! degree of pigmentation
relationship: is_opposite_of PATO:0002248 ! pigmented
created_by: george
creation_date: 2010-08-09T04:17:04Z

[Term]
id: PATO:0002250
name: increased pigmentation
namespace: quality
def: "A degree of pigmentation quality that is relatively high." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "hyperpigmented" EXACT []
is_a: PATO:0002248 ! pigmented
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0002248 ! pigmented
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002251 ! decreased pigmentation
created_by: george
creation_date: 2010-08-09T04:17:19Z

[Term]
id: PATO:0002251
name: decreased pigmentation
namespace: quality
def: "A degree of pigmentation quality that is relative low." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "hypopigmented" EXACT []
is_a: PATO:0002248 ! pigmented
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0002248 ! pigmented
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002250 ! increased pigmentation
created_by: george
creation_date: 2010-08-09T04:17:37Z

[Term]
id: PATO:0002254
name: flattened
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS]
comment: Becoming flat but not necessarily completely flat.
subset: value_slim
synonym: "compressed" RELATED []
is_a: PATO:0001591 ! curvature
created_by: george
creation_date: 2010-08-16T03:59:34Z

[Term]
id: PATO:0002259
name: adjacent to
namespace: quality
alt_id: PATO:0001771
def: "A spatial quality inhering in a bearer by virtue of the bearer's being located near in space in relation to another entity." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "approaches" EXACT []
synonym: "close to" EXACT []
synonym: "near to" EXACT []
synonym: "vicinity of" EXACT []
is_a: PATO:0000140 ! position
created_by: george
creation_date: 2010-09-08T03:20:06Z

[Term]
id: PATO:0002260
name: semi erect
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's being partially upright in position or posture." [PATOC:GVG]
synonym: "semi upright" EXACT []
is_a: PATO:0000622 ! erect
created_by: george
creation_date: 2010-09-08T03:27:21Z

[Term]
id: PATO:0002264
name: organization quality
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's being arranged in a systematic fashion." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000141 ! structure
created_by: george
creation_date: 2010-09-16T10:22:52Z

[Term]
id: PATO:0002266
name: 3-D shape
namespace: quality
def: "A shape that inheres in a 3 dimensional entity." [PATOC:OREGON]
is_a: PATO:0000052 ! shape
created_by: george
creation_date: 2010-10-05T12:31:16Z

[Term]
id: PATO:0002282
name: increased mobility
namespace: quality
def: "A mobility which is relative high." [PATO:GVG]
subset: value_slim
is_a: PATO:0000299 ! mobile
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000299 ! mobile
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002283 ! decreased mobility
created_by: george
creation_date: 2011-03-09T09:16:03Z

[Term]
id: PATO:0002283
name: decreased mobility
namespace: quality
def: "A mobility which is relative low." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000299 ! mobile
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000299 ! mobile
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002282 ! increased mobility
created_by: george
creation_date: 2011-03-09T09:16:47Z

[Term]
id: PATO:0002285
name: increased branchiness
namespace: quality
def: "Branchiness quality inhering in a bearer by virtue of increasing the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:CVS]
subset: value_slim
is_a: PATO:0000402 ! branched
relationship: is_opposite_of PATO:0002286 ! decreased branchiness
created_by: george
creation_date: 2011-03-10T09:07:57Z

[Term]
id: PATO:0002286
name: decreased branchiness
namespace: quality
def: "Branchiness quality inhering in a bearer by virtue of decreasing the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:CVS]
subset: value_slim
is_a: PATO:0000402 ! branched
relationship: is_opposite_of PATO:0002285 ! increased branchiness
created_by: george
creation_date: 2011-03-10T09:08:37Z

[Term]
id: PATO:0002290
name: aplastic/hypoplastic
namespace: quality
is_a: PATO:0001241 ! physical object quality
created_by: George Gkoutos
creation_date: 2011-04-18T05:11:33Z

[Term]
id: PATO:0002291
name: agenesis
namespace: quality
def: "Absence of a tissue or organ due to failure to develop." [PATO:GVG]
is_a: PATO:0000462 ! absent
created_by: George Gkoutos
creation_date: 2011-04-18T05:17:34Z

[Term]
id: PATO:0002300
name: increased quality
namespace: quality
def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG]
is_a: PATO:0000069 ! deviation(from_normal)
intersection_of: PATO:0000001 ! quality
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002301 ! decreased quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:39:43Z

[Term]
id: PATO:0002301
name: decreased quality
namespace: quality
def: "A quality that has a value that is decreased compared to normal or average." [PATOC:GVG]
is_a: PATO:0000069 ! deviation(from_normal)
intersection_of: PATO:0000001 ! quality
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002300 ! increased quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:40:15Z

[Term]
id: PATO:0002302
name: decreased process quality
namespace: quality
def: "A quality of a process that has a value that is decreased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001236 ! process quality
is_a: PATO:0002301 ! decreased quality
intersection_of: PATO:0001236 ! process quality
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002304 ! increased process quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:50:59Z

[Term]
id: PATO:0002303
name: decreased object quality
namespace: quality
def: "A quality of an object that has a value that is decreased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001241 ! physical object quality
is_a: PATO:0002301 ! decreased quality
intersection_of: PATO:0001241 ! physical object quality
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002305 ! increased object quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:51:54Z

[Term]
id: PATO:0002304
name: increased process quality
namespace: quality
def: "A quality of a process that has a value that is increased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001236 ! process quality
is_a: PATO:0002300 ! increased quality
intersection_of: PATO:0001236 ! process quality
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002302 ! decreased process quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:53:08Z

[Term]
id: PATO:0002305
name: increased object quality
namespace: quality
def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001241 ! physical object quality
is_a: PATO:0002300 ! increased quality
intersection_of: PATO:0001241 ! physical object quality
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002303 ! decreased object quality
created_by: George Gkoutos
creation_date: 2011-06-16T06:54:01Z

[Term]
id: PATO:0002312
name: segmented
namespace: quality
def: "Consisting of segments or similar parts arranged in a longitudinal series." [OED:]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure
created_by: George Gkoutos
creation_date: 2011-10-03T03:42:23Z

[Term]
id: PATO:0002318
name: superelliptic
namespace: quality
def: "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" [wiktionary:superellipse]
synonym: "Lamé curve" EXACT []
is_a: PATO:0002006 ! 2-D shape
created_by: George Gkoutos
creation_date: 2011-10-12T12:45:16Z

[Term]
id: PATO:0002323
name: temporal distribution quality
namespace: quality
def: "A temporal distribution pattern of process occurrences within a regulation/reference process." [PATOC:LC]
subset: attribute_slim
is_a: PATO:0002062 ! physical quality of a process
created_by: George Gkoutos
creation_date: 2011-11-22T01:12:28Z

[Term]
id: PATO:0002324
name: offset quality
namespace: quality
def: "The temporal relation between the end of the process with respect to a reference process." [PATOC:LC]
subset: attribute_slim
synonym: "completeness" RELATED [GOC:CJM]
synonym: "extent" RELATED [GOC:CJM]
is_a: PATO:0002323 ! temporal distribution quality
created_by: George Gkoutos
creation_date: 2011-11-23T11:46:00Z

[Term]
id: PATO:0002325
name: onset quality
namespace: quality
def: "The temporal relation between the start of the process with respect to a reference process." [PATOC:LC]
subset: attribute_slim
synonym: "initiation" RELATED []
is_a: PATO:0002323 ! temporal distribution quality
created_by: George Gkoutos
creation_date: 2011-11-23T11:47:34Z

[Term]
id: PATO:0002326
name: angle
namespace: quality
def: "An orientation inhering in a bearer by virtue of the bearer's placement at an angle." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
is_a: PATO:0000133 ! orientation
created_by: George Gkoutos
creation_date: 2011-11-23T12:06:09Z

[Term]
id: PATO:0002327
name: increased angle to
namespace: quality
def: "An angle which is relatively high." [PATOC:GVG]
subset: relational_slim
subset: value_slim
is_a: PATO:0001475 ! increased position
is_a: PATO:0002326 ! angle
intersection_of: PATO:0002326 ! angle
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002328 ! decreased angle to
created_by: George Gkoutos
creation_date: 2011-11-23T12:06:38Z

[Term]
id: PATO:0002328
name: decreased angle to
namespace: quality
def: "An angle which is relatively low." [PATOC:GVG]
subset: relational_slim
subset: value_slim
is_a: PATO:0001476 ! decreased position
is_a: PATO:0002326 ! angle
intersection_of: PATO:0002326 ! angle
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002327 ! increased angle to
created_by: George Gkoutos
creation_date: 2011-11-23T12:06:54Z

[Term]
id: PATO:0002331
name: adhesive
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer exhibiting molecular attraction to another entity in contact." [PATOC:GVG]
subset: value_slim
synonym: "resinous" RELATED []
is_a: PATO:0001431 ! adhesivity
relationship: is_opposite_of PATO:0002332 ! non-adhesive
created_by: gkoutos
creation_date: 2012-01-31T12:28:16Z

[Term]
id: PATO:0002332
name: non-adhesive
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer not exhibiting molecular attraction to another entity in contact." [PATOC:GVG]
subset: value_slim
synonym: "non-resinous" RELATED []
is_a: PATO:0001431 ! adhesivity
relationship: is_opposite_of PATO:0002331 ! adhesive
created_by: gkoutos
creation_date: 2012-01-31T12:28:57Z

[Term]
id: PATO:0002333
name: increased adhesivity
namespace: quality
def: "A adhesivity which is relatively high." [PATOC:GVG]
subset: value_slim
is_a: PATO:0002305 ! increased object quality
is_a: PATO:0002331 ! adhesive
intersection_of: PATO:0002331 ! adhesive
intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002334 ! decreased adhesivity
created_by: gkoutos
creation_date: 2012-01-31T12:32:43Z

[Term]
id: PATO:0002334
name: decreased adhesivity
namespace: quality
def: "A adhesivity which is relatively low." [PATOC:GVG]
is_a: PATO:0002303 ! decreased object quality
is_a: PATO:0002331 ! adhesive
intersection_of: PATO:0002331 ! adhesive
intersection_of: decreased_in_magnitude_relative_to PATO:0000461 ! normal
relationship: is_opposite_of PATO:0002333 ! increased adhesivity
created_by: gkoutos
creation_date: 2012-01-31T12:42:22Z

[Term]
id: PATO:0002364
name: shortened
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's length being notably lower than its width." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000052 ! shape
relationship: is_opposite_of PATO:0001154 ! elongated
created_by: gkoutos
creation_date: 2012-04-18T06:31:29Z

[Term]
id: PATO:0002395
name: mislocalized abaxially
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer's being positioned away from the axis of an organism." [PATOC:EH]
subset: value_slim
is_a: PATO:0000628 ! mislocalised
created_by: gkoutos
creation_date: 2012-11-20T04:13:32Z

[Term]
id: PATO:0002452
name: decondensed
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer being thinner or more losely packed." [PATOC:JL]
subset: value_slim
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0001485 ! condensed
created_by: gkoutos
creation_date: 2013-04-08T08:43:31Z

[Term]
id: PATO:0002463
name: extends to
namespace: quality
def: "A positional quality inhering in a bearer by virtue of some aspect of the bearer extending to the position of another entity." [PATOC:WD]
subset: relational_slim
is_a: PATO:0000140 ! position
created_by: gkoutos
creation_date: 2013-09-15T11:41:00Z

[Term]
id: PATO:0002470
name: transformed to
namespace: quality
def: "A morphological quality between two bearers inhering that one bearer is subject to change the nature, function, or condition of itself to become the other." [PATOC:LC]
subset: relational_slim
subset: value_slim
is_a: PATO:0000051 ! morphology
created_by: gkoutos
creation_date: 2013-09-15T12:01:57Z

[Term]
id: PATO:0002481
name: oblique orientation
namespace: quality
def: "An orientation quality inhering in a bearer by virtue of the bearer having a slanting direction or position : neither perpendicular nor parallel." [merriam-wester:http\://www.merriam-webster.com/dictionary/oblique]
subset: value_slim
is_a: PATO:0000133 ! orientation
created_by: gkoutos
creation_date: 2013-09-30T05:49:50Z

[Term]
id: PATO:0002505
name: nucleated
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0001404 ! nucleate quality
created_by: gkoutos
creation_date: 2013-10-21T05:44:34Z

[Term]
id: PATO:0002508
name: concealed
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer being hidden from view." [PATOC:EJS]
subset: value_slim
is_a: PATO:0000140 ! position
created_by: segerdel
creation_date: 2014-02-04T01:30:21Z

[Term]
id: PATO:0002516
name: concealed by
namespace: quality
def: "A positional quality inhering in a bearer by virtue of the bearer being hidden from view or covered by another entity." [PATOC:EJS]
subset: relational_slim
subset: value_slim
is_a: PATO:0000140 ! position
created_by: segerdel
creation_date: 2014-02-10T01:13:53Z

[Term]
id: PATO:0005012
name: complete structure
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer being fully formed compared to entities lacking parts." [PATOC:WD]
subset: value_slim
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0005013 ! incomplete structure
created_by: wasila.dahdul
creation_date: 2014-09-25T15:11:47Z

[Term]
id: PATO:0005013
name: incomplete structure
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's lacking parts or having a reduced form compared to fully formed entities." [PATOC:WD]
subset: value_slim
is_a: PATO:0000141 ! structure
relationship: is_opposite_of PATO:0005012 ! complete structure
created_by: wasila.dahdul
creation_date: 2014-09-25T15:12:35Z

[Term]
id: PATO:0005020
name: irregularly shaped
namespace: quality
def: "A shape quality inhering on a bearer by virtue of a bearer's shape lacking in pattern or uniformity; for example, it may have sides of different lengths, different curvatures, or unequal angles." [PATOC:WD]
subset: value_slim
is_a: PATO:0000052 ! shape
created_by: wasila.dahdul
creation_date: 2014-10-03T10:23:17Z

[Term]
id: PATO:0030000
name: anterioralized
namespace: quality
def: "A malformed quality inhering in a bearer by virtue of the bearer's gross morphology containing what are normally anterior structures and missing some or all of what are normally posterior structures." [PATOC:EJS]
is_a: PATO:0000646 ! malformed
created_by: segerdel

[Term]
id: PATO:0030001
name: dorsalized
namespace: quality
def: "A malformed quality inhering in a bearer by virtue of the bearer's gross morphology containing what are normally dorsal structures and missing some or all of what are normally ventral structures." [PATOC:EJS]
is_a: PATO:0000646 ! malformed
created_by: segerdel

[Term]
id: PATO:0030002
name: posterioralized
namespace: quality
def: "A malformed quality inhering in a bearer by virtue of the bearer's gross morphology containing what are normally posterior structures and missing some or all of what are normally anterior structures." [PATOC:EJS]
is_a: PATO:0000646 ! malformed
created_by: segerdel

[Term]
id: PATO:0030003
name: ventralized
namespace: quality
def: "A malformed quality inhering in a bearer by virtue of the bearer's gross morphology containing what are normally ventral structures and missing some or all of what are normally dorsal structures." [PATOC:EJS]
is_a: PATO:0000646 ! malformed
created_by: segerdel

[Term]
id: Subset
is_a: IAO:0000102 ! data about an ontology part

[Term]
id: XAO:0000000
name: Xenopus anatomical entity
namespace: xenopus_anatomy
def: "Entity that is either an individual member of Xenopus or constitutes the structural organization of an individual member Xenopus." [CARO:0000000, XAO:EJS]
xref: CARO:0000000

[Term]
id: XAO:0000001
name: ectoderm
namespace: xenopus_anatomy
def: "Primary germ layer that is the outer of the embryo's germ layers and gives rise to epidermis and neural tissue." [http://dictionary.reference.com/medical/ectoderm]
subset: frequent_anatomy_items
xref: UBERON:0000924
is_a: XAO:0003011 ! primary germ layer

[Term]
id: XAO:0000002
name: fin
namespace: xenopus_anatomy
def: "Surface structure that has an important role in tadpole locomotion. It starts to develop along the trunk and tail of the embryo at the tail bud stage and continues to grow until the start of metamorphosis when it begins to regress. It consists of flattened epidermal cells elevated into a keel-like structure by a supporting core of mesenchyme and extracellular matrix." [PMID:15188431]
subset: frequent_anatomy_items
xref: UBERON:0008897
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000003
name: outer fin
namespace: xenopus_anatomy
def: "Part of the fin consisting of flattened epidermal cells elevated into a keel-like structure." [PMID:15188431]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000002 ! fin
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000004
name: inner fin
namespace: xenopus_anatomy
def: "Part of the fin consisting of a supporting core of mesenchyme and extracellular matrix." [PMID:15188431]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000002 ! fin
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000005
name: olfactory placode
namespace: xenopus_anatomy
def: "A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory epithelium of the nasal cavity." [http://www.merriam-webster.com/medlineplus/olfactory+placode]
synonym: "nasal placode" RELATED []
xref: UBERON:0003050
is_a: XAO:0004620 ! neurogenic placode
relationship: develops_from XAO:0000041 ! epidermis inner layer
relationship: develops_from XAO:0004206 ! anterior placodal area
relationship: develops_from XAO:0004209 ! anterior neural ridge
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000006
name: otic vesicle
namespace: xenopus_anatomy
alt_id: XAO:0000184
def: "The saccular invagination of ectoderm from which the vertebrate inner ear develops." [UBERON:0003051]
subset: frequent_anatomy_items
synonym: "ear" BROAD []
synonym: "ear vesicle" RELATED []
synonym: "otocyst" RELATED []
xref: UBERON:0003051
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000223 ! otic placode
relationship: end_stage XAO:1000070 ! NF stage 58
relationship: part_of XAO:0003195 ! vestibuloauditory system
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000007
name: lower eyelid
namespace: xenopus_anatomy
def: "A surface structure consisting of a set of membranes that cover and protect the eye." [http://en.wikipedia.org/wiki/Frog]
xref: UBERON:0001713
is_a: XAO:0003028 ! surface structure
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000074 ! NF stage 62

[Term]
id: XAO:0000008
name: lens
namespace: xenopus_anatomy
def: "Transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina." [http://en.wikipedia.org/wiki/Lens_(anatomy)]
xref: UBERON:0000965
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000240 ! lens placode
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000009
name: retina
namespace: xenopus_anatomy
def: "Sensory membrane that lines the posterior chamber of the eye and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve." [http://www.merriam-webster.com/medlineplus/retina]
xref: UBERON:0000966
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000010
name: brain
namespace: xenopus_anatomy
def: "Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place." [http://dictionary.reference.com/medical/brain, ISBN:0815318960]
subset: frequent_anatomy_items
xref: UBERON:0000955
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0003204 ! neural tube
relationship: part_of XAO:0000215 ! central nervous system
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000011
name: forebrain
namespace: xenopus_anatomy
def: "The part of the brain that is the anterior of its three primary divisions and that includes the telencephalon and diencephalon." [http://www.merriam-webster.com/medlineplus/forebrain]
synonym: "prosencephalon" RELATED []
xref: UBERON:0001890
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000307 ! anterior neural tube
relationship: part_of XAO:0000010 ! brain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000012
name: telencephalon
namespace: xenopus_anatomy
def: "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres." [AAO:0010479]
xref: UBERON:0001893
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000011 ! forebrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000013
name: diencephalon
namespace: xenopus_anatomy
def: "The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye vescile, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis)." [XAO:curators]
xref: UBERON:0001894
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000011 ! forebrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000014
name: midbrain
namespace: xenopus_anatomy
def: "Middle part of the brain composed of the optic tectum and penducular region." [AAO:0010149]
synonym: "mesencephalon" RELATED []
xref: UBERON:0001891
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000307 ! anterior neural tube
relationship: part_of XAO:0000010 ! brain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000015
name: hindbrain
namespace: xenopus_anatomy
def: "The part of the brain that is the posterior of its three primary divisions." [http://www.merriam-webster.com/medlineplus/hindbrain]
synonym: "rhombencephalon" RELATED []
xref: UBERON:0002028
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000250 ! posterior neural tube
relationship: part_of XAO:0000010 ! brain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000016
name: midbrain-hindbrain boundary
namespace: xenopus_anatomy
def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [UBERON:0003052]
synonym: "isthmic organizer territory" RELATED []
synonym: "isthmus" RELATED []
synonym: "MHB" EXACT []
xref: UBERON:0003052
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0004003 ! anatomical line
relationship: develops_from XAO:0004086 ! presumptive midbrain-hindbrain boundary
relationship: part_of XAO:0000010 ! brain
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000017
name: hypophysis
namespace: xenopus_anatomy
alt_id: XAO:0000161
def: "An endocrine gland, located ventral to the diencephalon, that secretes hormones that regulate many other glands." [UBERON:0000007]
synonym: "Hyp" EXACT []
synonym: "pituitary" RELATED []
synonym: "pituitary gland" RELATED []
xref: UBERON:0000007
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000267 ! hypophyseal primordium
relationship: develops_from XAO:0004208 ! adenohypophyseal placode
relationship: part_of XAO:0000011 ! forebrain
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000018
name: genital ridge
namespace: xenopus_anatomy
def: "Portion of tissue that is the precursor to the gonads." [http://en.wikipedia.org/wiki/Gonadal_ridge]
xref: UBERON:0005294
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: end_stage XAO:1000064 ! NF stage 52
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000020
name: spinal cord
namespace: xenopus_anatomy
def: "Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge." [http://dictionary.reference.com/medical/spinal+cord]
xref: UBERON:0002240
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000250 ! posterior neural tube
relationship: part_of XAO:0000215 ! central nervous system
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000021
name: ventricular zone
namespace: xenopus_anatomy
def: "Proliferative region that is part of the ventricular system of the brain." [VHOG:0001224]
subset: anatomical_site_slim
xref: UBERON:0003053
is_a: XAO:0003186 ! anatomical region
relationship: part_of XAO:0000010 ! brain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000022
name: roof plate
namespace: xenopus_anatomy
def: "Organizing center located at the dorsal midline of the neural tube that influences the development of the nervous system, controlling the specification and differentiation of dorsal neuronal cell types." [PMID:15378040]
synonym: "roofplate" EXACT []
synonym: "spinal cord roof" RELATED []
xref: UBERON:0005724
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0005241 ! superficial layer of neurectoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000023
name: skin
namespace: xenopus_anatomy
def: "Surface structure that consists of the external membranous integument of the animal." [http://dictionary.reference.com/medical/skin]
synonym: "integument" RELATED []
xref: UBERON:0002097
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000028 ! epidermis
relationship: part_of XAO:0000176 ! dermal system
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000024
name: mandibular crest
namespace: xenopus_anatomy
def: "The most anterior of the migrating cranial neural crest streams, running along the posterior edge of the eye primordium, and in later stages, below the eye and to the border of the cement gland. The mandibular stream is the first to initiate CNC cell migration." [PMID:21490068]
xref: UBERON:0007098
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0001001 ! cranial neural crest
relationship: end_stage XAO:1000054 ! NF stage 42
relationship: part_of XAO:0001001 ! cranial neural crest
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0000025
name: hyoid crest
namespace: xenopus_anatomy
def: "The second most anterior of the migrating cranial neural crests streams, it lays between the mandibular and anterior branchial crest streams." [PMID:21490068]
synonym: "hyoid neural crest" EXACT []
xref: UBERON:0007099
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0001001 ! cranial neural crest
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0001001 ! cranial neural crest
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0000026
name: branchial crest
namespace: xenopus_anatomy
def: "The most posterior segments of the population of migratory cells of the cranial neural crest, contributing to the branchial arches 3 and 4. Branchial crest cells migrate in two distinct streams referred to as the anterior and posterior branchial crest." [XAO:CJZ]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000048 ! neural crest
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0001001 ! cranial neural crest
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0000027
name: cranial ganglion
namespace: xenopus_anatomy
def: "Ganglion that is located in the head." [XAO:EJS, ZFA:0000013]
synonym: "cranial ganglia" RELATED PLURAL []
xref: UBERON:0001714
is_a: XAO:0000209 ! ganglion
relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000028
name: epidermis
namespace: xenopus_anatomy
def: "The outer epithelial layer of the external integument of the body that is derived from the primative or embryonic ectoderm." [AAO:0000143]
subset: frequent_anatomy_items
synonym: "skin" BROAD []
xref: UBERON:0001003
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0004091 ! non-neural ectoderm
relationship: part_of XAO:0000001 ! ectoderm
relationship: part_of XAO:0000023 ! skin

[Term]
id: XAO:0000029
name: epidermis outer layer
namespace: xenopus_anatomy
def: "The outermost layer of the epidermis, the multilayered epithelium derived from the ectoderm." [XAO:curators]
synonym: "epidermis epithelial layer" RELATED []
synonym: "periderm" RELATED []
xref: UBERON:0003055
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0000028 ! epidermis
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000030
name: vitelline membrane
namespace: xenopus_anatomy
def: "The membrane enveloping the egg or oocyte, lying immediately outside the plasmalemma. It is formed while the oocyte is in the ovary and it separates from the egg to form the fertilization membrane." [AAO:0010332, XAO:curators]
xref: UBERON:0003125
is_a: XAO:0004005 ! extraembryonic structure
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: part_of XAO:0000035 ! zygote
relationship: start_stage XAO:1000092 ! mature egg stage

[Term]
id: XAO:0000031
name: ciliated epidermal cell
namespace: xenopus_anatomy
def: "Cell type that has motile cilia and populates the skin of the embryo, arranged in the surface layer of the non-neural ectoderm in an ordered distribution." [PMID:10518489]
synonym: "ciliated cell" BROAD []
synonym: "epidermal ciliary cell" EXACT []
xref: CL:0007018
is_a: XAO:0004621 ! epidermal cell
is_a: XAO:0005017 ! ciliated cell

[Term]
id: XAO:0000032
name: stomodeal-hypophyseal primordium
namespace: xenopus_anatomy
def: "An anterior thickening of the sensorial layer of ectoderm, just above the cement gland. The hypophyseal layer separates from the stomodeal layer at NF stage 29 and 30, and when contacted by a protrusion of the foregut, the stomodeal layer will rupture to form the mouth opening at NF stage 39 and 40." [XAO:curators]
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000001 ! ectoderm
relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000033
name: cement gland
namespace: xenopus_anatomy
def: "A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm." [PMID:8787748]
subset: frequent_anatomy_items
xref: UBERON:0005093
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000049 ! cement gland primordium
relationship: end_stage XAO:1000062 ! NF stage 50
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000034
name: hatching gland
namespace: xenopus_anatomy
def: "A Y-shaped array of unicelluar glands on the top of the head, the open end of which faces anteriorly, that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching. Presumptive cells of the hatching gland are present by the end of gastrualtion (NF stage 12.5) and differentiated cells start to form after neurulation is complete (NF stage 21)." [XAO:curators]
synonym: "frontal gland" RELATED []
xref: UBERON:0002538
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0004394 ! hatching gland primordium
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0000035
name: zygote
namespace: xenopus_anatomy
def: "Cell resulting from the fusion of male and female gametes at fertilization." [http://dictionary.reference.com/medical/zygote]
synonym: "fertilized egg" EXACT []
xref: CL:0000365
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0000036
name: animal cap
namespace: xenopus_anatomy
def: "Ectodermal roof of the blastocoel." [XAO:curators]
synonym: "animal ectoderm" RELATED []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell)

[Term]
id: XAO:0000037
name: animal cap inner layer
namespace: xenopus_anatomy
def: "Sensorial layer of blastocoel roof ectoderm." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000036 ! animal cap

[Term]
id: XAO:0000038
name: animal cap outer layer
namespace: xenopus_anatomy
def: "Superficial layer of blastocoel roof ectoderm." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000036 ! animal cap

[Term]
id: XAO:0000040
name: head region
namespace: xenopus_anatomy
def: "The anterior-most third of the embryo, formed from the development of the head outgrowth at NF stage 21." [XAO:curators]
subset: anatomical_site_slim
xref: UBERON:0001444
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000041
name: epidermis inner layer
namespace: xenopus_anatomy
def: "A distinct layer of the epidermal cells beneath the outermost layer of epidermis, the multilayered epithelium derived from the ectoderm." [XAO:curators]
synonym: "epidermis sensorial layer" RELATED []
synonym: "stratum germinativum" RELATED []
xref: UBERON:0002025
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000028 ! epidermis
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000042
name: neuroectoderm
namespace: xenopus_anatomy
def: "Embryonic ectoderm that gives rise to nervous tissue." [http://www.merriam-webster.com/medlineplus/neuroectoderm]
synonym: "neural ectoderm" RELATED []
synonym: "neurectoderm" EXACT []
synonym: "presumptive central nervous system" RELATED []
xref: UBERON:0002346
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000043
name: neuroectoderm outer layer
namespace: xenopus_anatomy
def: "Superficial neuroectoderm layer consisting of horizontally flattened, pigmented cells." [PMID:2642003]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000044
name: neuroectoderm inner layer
namespace: xenopus_anatomy
def: "Deep neuroectoderm layer consisting of densely packed, cylindrical, unpigmented cells." [PMID:2642003]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000045
name: pre-chordal neural plate
namespace: xenopus_anatomy
def: "The portion of neural plate anterior to the mid-hindbrain junction." [XAO:curators]
synonym: "anterior neural plate" RELATED []
xref: UBERON:0003056
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000046
name: chordal neural plate
namespace: xenopus_anatomy
def: "The portion of neural plate posterior to the mid-hindbrain junction." [XAO:curators]
synonym: "posterior neural plate" RELATED []
xref: UBERON:0003057
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000047
name: notoplate
namespace: xenopus_anatomy
def: "Region of the neural plate overlying the notochord." [http://www.encyclo.co.uk/define/Notoplate]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000033 ! NF stage 12.5

[Term]
id: XAO:0000048
name: neural crest
namespace: xenopus_anatomy
def: "A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchymal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem cell-like." [AAO:0010578, XAO:CJZ]
subset: frequent_anatomy_items
synonym: "NC" EXACT []
synonym: "neural crest material" RELATED []
xref: UBERON:0002342
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm
relationship: develops_from XAO:0004103 ! chordal neural plate border
relationship: develops_from XAO:0004104 ! neural plate border
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000049
name: cement gland primordium
namespace: xenopus_anatomy
def: "The thickening of the epithelial layer of the ectoderm, with corresponding dark pigmentation, on the anterior dorso-ventral surface of the embryo." [ISBN:0070179778]
synonym: "adhesive organ primordium" EXACT []
synonym: "cement gland" BROAD []
synonym: "cement gland anlage" EXACT []
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000320 ! sensorial layer
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000050
name: mesoderm
namespace: xenopus_anatomy
def: "Primary germ layer that is the middle of the embryo's germ layers." [http://dictionary.reference.com/medical/mesoderm]
subset: frequent_anatomy_items
synonym: "mesodermal mantle" RELATED []
xref: UBERON:0000926
is_a: XAO:0003011 ! primary germ layer
relationship: develops_from XAO:0003044 ! endomesoderm

[Term]
id: XAO:0000051
name: dorsal aorta
namespace: xenopus_anatomy
def: "Principal unpaired, median artery of the trunk, extending into the tail as the caudal artery." [ISBN:0226557634]
synonym: "aorta dorsalis" EXACT []
xref: UBERON:0005805
is_a: XAO:0003010 ! aorta
relationship: develops_from XAO:0005019 ! paired dorsal aorta
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000052
name: cardinal vein
namespace: xenopus_anatomy
def: "The paired main vein, departing from the sinus venous, the fused heart primordium, it runs posteriorly down length of the embryo." [XAO:curators]
xref: UBERON:0004344
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium

[Term]
id: XAO:0000053
name: head mesoderm
namespace: xenopus_anatomy
def: "The mesoderm of the head." [XAO:curators]
xref: UBERON:0006904
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000079 ! prechordal plate
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000050 ! mesoderm
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0000054
name: trunk region
namespace: xenopus_anatomy
def: "The anatomical region of the body posterior to the head and anterior to the tail." [XAO:EJS]
subset: anatomical_site_slim
xref: UBERON:0002100
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0000055
name: notochord
namespace: xenopus_anatomy
def: "A longitudinal flexible rod of cells that in the embryo forms the supporting axis of the body. It degenerates, beginning anteriorly, at NF stage 46. Its posterior portion is greatly reduced by NF stage 55 and the entire structure is gone by NF stage 65." [http://www.merriam-webster.com/medlineplus/notochord, ISBN:0815318960]
subset: frequent_anatomy_items
xref: UBERON:0002328
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000205 ! axial mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000033 ! NF stage 12.5

[Term]
id: XAO:0000056
name: hypochord
namespace: xenopus_anatomy
def: "Transient structure that lies immediately ventral to the notochord in the embryo, likely required for the formation of the dorsal aorta. A slight depression marks the future hypochord at NF stage 20 and its segregation from the dorsal endoderm begins at NF stage 24. It progresses from anterior to posterior and is complete by NF stage 28. At NF stage 32 it is present as a dorso-laterally flattened ribbon of yolk-laden cells. It degenerates by apoptosis and by NF stage 43 is no longer detectable as a distinct structure in the trunk region of the tadpole. The most posterior hypochord persists and begins to ossify, fusing with the coccyx to form the urostyle in the pelvic girdle around NF stage 63." [ISBN:0815318960, PMID:10648245]
synonym: "ipochord" EXACT []
synonym: "subnotochordal rod" RELATED [PMID:10648245]
xref: UBERON:0003058
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000075 ! NF stage 63
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000057
name: presomitic mesoderm
namespace: xenopus_anatomy
def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." [UBERON:0003059]
synonym: "somitogenic mesoderm" RELATED []
xref: UBERON:0003059
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000259 ! paraxial mesoderm
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000259 ! paraxial mesoderm
relationship: part_of XAO:0004042 ! muscular system
relationship: start_stage XAO:1000024 ! NF stage 14

[Term]
id: XAO:0000058
name: somite
namespace: xenopus_anatomy
def: "Any of the approximately 45 bilaterally paired blocks of mesoderm cells, lying on either side of the notochord and neural tube, and forming sequentially starting at the head during development of the embryo. Together they give rise to the axial skeleton (from the sclerotome), associated musculature (from the myotome), and dermis (from the dermatome)." [http://dictionary.reference.com/medical/somite, XAO:curators]
subset: frequent_anatomy_items
synonym: "somites" RELATED PLURAL []
synonym: "somitic mesoderm" RELATED []
xref: UBERON:0002329
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000057 ! presomitic mesoderm
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000050 ! mesoderm
relationship: part_of XAO:0004042 ! muscular system
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000062
name: pronephric nephrostome
namespace: xenopus_anatomy
def: "Any of the ciliated tubules that collect the glomeral filtrate, passing it through to the pronephric tubules." [XAO:CJZ]
synonym: "nephrostome" EXACT []
xref: UBERON:0005308
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000264 ! pronephric mesenchyme
relationship: end_stage XAO:1000071 ! NF stage 59
relationship: part_of XAO:0002000 ! pronephric kidney
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000063
name: pronephric duct
namespace: xenopus_anatomy
def: "Duct that drains urine from the pronephros and connects it to the cloaca. It is thought that the pronephric duct may play a key role in the induction of the mesonephric (adult) kidney. The most anterior part of the pronephric duct shows distinct gene expression patterns and is sometimes referred to as DT2." [PMID:8365571, XAO:CJZ]
synonym: "common tubule" RELATED []
synonym: "connecting tubule" RELATED []
synonym: "distal tubule segment 2" EXACT []
synonym: "DT2" EXACT []
synonym: "nephric duct" EXACT []
synonym: "Wolffian duct" EXACT []
xref: UBERON:0003060
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000264 ! pronephric mesenchyme
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0002000 ! pronephric kidney

[Term]
id: XAO:0000064
name: heart
namespace: xenopus_anatomy
def: "A myogenic muscular organ found in the cardiovascular system. It is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions. It is composed of cardiac muscle, which is an involuntary striated muscle tissue found only in this organ, and connective tissue. It is ultimately composed of three chambers (two atria and one ventricle), occupying a ventral position within the chest of the mature tadpole/frog." [PMID:17194606, UBERON:0000948]
subset: frequent_anatomy_items
xref: UBERON:0000948
is_a: XAO:0003034 ! viscus
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000336 ! fused heart primordium
relationship: part_of XAO:0000100 ! cardiovascular system

[Term]
id: XAO:0000065
name: myocardium
namespace: xenopus_anatomy
def: "Cardiac muscle constituting the middle layer of the heart." [AAO:0010410]
synonym: "cardiac muscle" RELATED []
xref: UBERON:0002349
is_a: XAO:0000172 ! muscle
relationship: develops_from XAO:0000336 ! fused heart primordium
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000066
name: endocardium
namespace: xenopus_anatomy
def: "Part of the heart composed of thin serous membrane and endothelial tissue, that lines the interior of the heart." [AAO:0010408]
xref: UBERON:0002165
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000336 ! fused heart primordium
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000067
name: ventral blood island
namespace: xenopus_anatomy
def: "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates." [PMID:9618755]
synonym: "blood island" BROAD []
synonym: "VBI" EXACT []
synonym: "ventral lateral plate mesoderm" BROAD []
xref: UBERON:0003061
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000311 ! lateral plate mesoderm
relationship: develops_from XAO:0004473 ! ventral mesoderm
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000026 ! NF stage 16

[Term]
id: XAO:0000068
name: marginal zone
namespace: xenopus_anatomy
def: "Region of intermediate pigmentation between the pigmented animal hemisphere and the unpigmented vegetal hemisphere of the egg." [http://worms.zoology.wisc.edu/frogs/glossary.html]
xref: UBERON:0004879
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000022 ! NF stage 12

[Term]
id: XAO:0000069
name: ventral marginal zone
namespace: xenopus_anatomy
def: "Embryonic tissue region that will make the ventral mesoderm." [XAO:EJS]
synonym: "VMZ" EXACT []
is_a: XAO:0000068 ! marginal zone

[Term]
id: XAO:0000070
name: ventro-lateral marginal zone
namespace: xenopus_anatomy
def: "Region of the marginal zone extending from the ventral to lateral surface." [XAO:EJS]
is_a: XAO:0000068 ! marginal zone

[Term]
id: XAO:0000071
name: dorso-lateral marginal zone
namespace: xenopus_anatomy
def: "Region of the marginal zone extending from the dorsal to lateral surface." [XAO:EJS]
is_a: XAO:0000068 ! marginal zone

[Term]
id: XAO:0000072
name: dorsal marginal zone
namespace: xenopus_anatomy
def: "Marginal zone that is a key embryonic tissue region of the early gastrula stage embryo and that houses the Spemann-Mangold organizer." [PMID:17368611]
synonym: "DMZ" EXACT [PMID:17368611]
synonym: "organizer" RELATED []
synonym: "Spemann organizer" RELATED []
xref: UBERON:0003062
is_a: XAO:0000068 ! marginal zone

[Term]
id: XAO:0000074
name: involuting marginal zone
namespace: xenopus_anatomy
def: "Portion of the marginal zone of the embryo that turns inside the embryo during involution." [http://worms.zoology.wisc.edu/frogs/glossary.html]
synonym: "IMZ" EXACT []
is_a: XAO:0000068 ! marginal zone
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000075
name: involuting marginal zone mesenchymal layer
namespace: xenopus_anatomy
def: "Deep layers of the IMZ consisting of prospective migrating mesodermal cells (which will migrate into the interior and form the leading edge of the mesodermal mantle) and prospective converging and extending mesoderm." [ISBN:0123646200]
synonym: "deep involuting marginal zone" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000074 ! involuting marginal zone
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000076
name: involuting marginal zone epithelial layer
namespace: xenopus_anatomy
def: "Layer of prospective endoderm in the IMZ that will form the roof of the archenteron." [ISBN:0123646200]
synonym: "superficial involuting marginal zone" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000074 ! involuting marginal zone
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000077
name: bottle cell
namespace: xenopus_anatomy
def: "Cell type that is first to migrate inwards at the blastopore during gastrulation." [http://dictionary.reference.com/medical/bottle+cell]
is_a: XAO:0003244 ! gastrula cell

[Term]
id: XAO:0000078
name: blastopore lip
namespace: xenopus_anatomy
def: "The edge of the blastopore. Local invagination is caused by narrowing of bottle cells at the exterior edge of the blastula." [ISBN:0387537406]
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000208 ! blastopore
relationship: start_stage XAO:1000030 ! NF stage 10.25

[Term]
id: XAO:0000079
name: prechordal plate
namespace: xenopus_anatomy
def: "Mesodermal structure that lies anterior to the notochord and gives rise to head mesoderm." [VHOG:0000086]
xref: UBERON:0003063
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000050 ! mesoderm
relationship: part_of XAO:0000205 ! axial mesoderm
relationship: start_stage XAO:1000022 ! NF stage 12

[Term]
id: XAO:0000080
name: forelimb region
namespace: xenopus_anatomy
def: "The region from which the forelimb develops, first recognizable at NF stage 48, and distinct by NF stage 49." [XAO:curators]
subset: anatomical_site_slim
synonym: "fore limb region" EXACT []
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0000081
name: hindlimb region
namespace: xenopus_anatomy
def: "The region from which the hindlimb develops, first recognizable as a slight concentration of mesenchymal cells dorsal and lateral to the anal tube at NF stage 43. The epidermal layers thicken dramatically through to NF stage 48, and become vascularised by NF stage 49." [XAO:curators]
subset: anatomical_site_slim
synonym: "hind limb region" EXACT []
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000082
name: circumblastoporal collar
namespace: xenopus_anatomy
def: "Embryonic structure that develops around the closed blastopore." [PMID:22138030]
synonym: "circumblastoporal region" RELATED []
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000088 ! upper blastopore lip
relationship: develops_from XAO:0000089 ! lower blastopore lip
relationship: end_stage XAO:1000036 ! NF stage 20
relationship: start_stage XAO:1000022 ! NF stage 12

[Term]
id: XAO:0000083
name: involuted dorsal mesoderm
namespace: xenopus_anatomy
def: "Dorsal mesoderm that has grown and curled inward during gastrulation." [http://medical-dictionary.thefreedictionary.com/involution]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000025 ! NF stage 15
relationship: part_of XAO:0000082 ! circumblastoporal collar
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000084
name: involuted ventral mesoderm
namespace: xenopus_anatomy
def: "Ventral mesoderm that has grown and curled inward during gastrulation." [http://medical-dictionary.thefreedictionary.com/involution]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000025 ! NF stage 15
relationship: part_of XAO:0000082 ! circumblastoporal collar
relationship: start_stage XAO:1000031 ! NF stage 10.5

[Term]
id: XAO:0000085
name: intermediate mesoderm
namespace: xenopus_anatomy
def: "Mesoderm layer between somite and lateral plate. All components of the pronephric kidney arise from this." [AAO:0010575, XAO:CJZ]
xref: UBERON:0003064
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000311 ! lateral plate mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000086
name: ciliary marginal zone
namespace: xenopus_anatomy
def: "The region at the periphery of the retina where retinal stem cells are located. It is spatially ordered with respect to cellular development and differentiation, with the youngest and least-determined stem cells closest to the periphery, the proliferative retinoblasts in the middle, and postmitotic cells at the central edge." [PMID:15844194]
xref: UBERON:0003065
is_a: XAO:0004122 ! proliferative region
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000009 ! retina
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000087
name: tail region
namespace: xenopus_anatomy
def: "The anatomical region of the body posterior to the tail." [XAO:EJS]
subset: anatomical_site_slim
xref: UBERON:0006071
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0000088
name: upper blastopore lip
namespace: xenopus_anatomy
def: "Dorsal part of the blastopore lip, which forms as a result of the contraction of bottle cells." [XAO:EJS]
synonym: "dorsal blastopore lip" RELATED []
synonym: "organizer" BROAD []
synonym: "Spemann organizer" BROAD []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000078 ! blastopore lip
relationship: start_stage XAO:1000030 ! NF stage 10.25

[Term]
id: XAO:0000089
name: lower blastopore lip
namespace: xenopus_anatomy
def: "Ventral part of the blastopore lip, which forms as a result of the contraction of bottle cells." [XAO:EJS]
synonym: "ventral blastopore groove" RELATED []
synonym: "ventral blastopore lip" RELATED []
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000078 ! blastopore lip
relationship: start_stage XAO:1000030 ! NF stage 10.25

[Term]
id: XAO:0000090
name: endoderm
namespace: xenopus_anatomy
def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [http://dictionary.reference.com/medical/endoderm]
subset: frequent_anatomy_items
synonym: "entoderm" RELATED []
xref: UBERON:0000925
is_a: XAO:0003011 ! primary germ layer
relationship: develops_from XAO:0003044 ! endomesoderm

[Term]
id: XAO:0000091
name: head endoderm
namespace: xenopus_anatomy
def: "The endoderm of the head." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000090 ! endoderm
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000092
name: archenteron
namespace: xenopus_anatomy
def: "The cavity of the gastrula forming a primitive gut. At NF stage 20-21 its wide canal becomes dorso-ventrally compressed and narrowed in the future trunk region so that a subdivision into a foregut, a midgut and a hindgut with protruding endodermal mass becomes manifest." [http://www.merriam-webster.com/medlineplus/archenteron, ISBN:0815318960]
synonym: "gastrocoel" RELATED []
xref: UBERON:0004735
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000093
name: archenteron floor
namespace: xenopus_anatomy
def: "The layer of cells forming the ventral surface of the archenteron space of the embryo." [PMID:17540356]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000281 ! vegetal yolk mass
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: part_of XAO:0000092 ! archenteron
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000094
name: gastrocoel roof plate
namespace: xenopus_anatomy
def: "A transient ciliated epithelium that arises from the involuting superficial mesoderm, forming the dorsal surface of the archenteron space of the embryo." [PMID:17540356, XAO:EJS]
synonym: "archenteron roof" EXACT []
synonym: "archenteron roof plate" EXACT []
synonym: "gastrocoel roof" EXACT []
synonym: "GRP" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000077 ! bottle cell
relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: part_of XAO:0000092 ! archenteron
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000095
name: lateral line system
namespace: xenopus_anatomy
def: "Sensory system that has as it parts the sense organs that detect vibrations carried through water, develops during late tailbud stage, and persists in the adult bearing elaborate dorsal and ventral components. It develops from a specialized series of dorsolateral ectodermal placodes named lateral line placodes." [AAO:0000975, ISBN:0471209627, ISBN:0815318960]
synonym: "lateral line stitches" RELATED []
synonym: "lateral-line organs" RELATED []
xref: UBERON:0002540
is_a: XAO:0003194 ! sensory system
relationship: part_of XAO:0000178 ! peripheral nervous system
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000096
name: pharyngeal arch
namespace: xenopus_anatomy
def: "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [http://www.merriam-webster.com/medlineplus/branchial+arch]
subset: frequent_anatomy_items
synonym: "pharyngeal arches" RELATED PLURAL []
synonym: "visceral arch" RELATED []
xref: UBERON:0002539
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000097
name: mandibular arch
namespace: xenopus_anatomy
def: "The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [XAO:EJS]
synonym: "first visceral arch" RELATED []
xref: UBERON:0004362
is_a: XAO:0000096 ! pharyngeal arch
relationship: develops_from XAO:0000102 ! visceral pouch 1
relationship: part_of XAO:0003176 ! splanchnocranium

[Term]
id: XAO:0000098
name: hyoid arch
namespace: xenopus_anatomy
def: "The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [XAO:EJS]
synonym: "second visceral arch" RELATED []
xref: UBERON:0003066
is_a: XAO:0000096 ! pharyngeal arch
relationship: develops_from XAO:0000247 ! visceral pouch 2

[Term]
id: XAO:0000099
name: branchial arch
namespace: xenopus_anatomy
def: "Structures that develop from the pharyngeal arches. Pharyngeal arches are anlage for a multitude of structures. Each pharyngeal arch has a cartilaginous stick, a muscle component which differentiates from the cartilaginous tissue, an artery, and a cranial nerve. Each of these is surrounded by mesenchyme. Arches do not develop simultaneously, but instead possess a staggered development." [ISBN:0023771100]
synonym: "branchial arches" RELATED PLURAL []
xref: UBERON:0008896
is_a: XAO:0000096 ! pharyngeal arch
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000100
name: cardiovascular system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088]
xref: UBERON:0004535
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0000101
name: liver diverticulum
namespace: xenopus_anatomy
def: "An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Its anterior portion gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder, hepato-pancreatic duct, hepato-pancreatic progenitor cells and the bile duct." [UBERON:0008835]
xref: UBERON:0008835
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000092 ! archenteron
relationship: develops_from XAO:0004513 ! foregut endoderm
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000232 ! foregut
relationship: start_stage XAO:1000024 ! NF stage 14

[Term]
id: XAO:0000102
name: visceral pouch 1
namespace: xenopus_anatomy
def: "First of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634]
synonym: "first visceral pouch" EXACT []
xref: UBERON:0007122
is_a: XAO:0000282 ! visceral pouch

[Term]
id: XAO:0000103
name: midgut
namespace: xenopus_anatomy
def: "Middle subdivision of the digestive tract. The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is often referred to as the \"midgut loop\". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon." [UBERON:0001045, XAO:curators]
xref: UBERON:0001045
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000092 ! archenteron
relationship: develops_from XAO:0004512 ! midgut primordium
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000104
name: hindgut
namespace: xenopus_anatomy
def: "Posterior subdivision of the digestive tract. The posterior part of the alimentary canal, including the large intestine and cloaca." [UBERON:0001046, XAO:curators]
xref: UBERON:0001046
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000092 ! archenteron
relationship: develops_from XAO:0004511 ! hindgut primordium
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000105
name: pharyngeal cavity
namespace: xenopus_anatomy
def: "The space enclosed by the walls of the pharynx." [BTO:0002097]
xref: UBERON:0001731
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000232 ! foregut
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000106
name: post-anal gut
namespace: xenopus_anatomy
def: "Tissue that is a temporary extension of the embryonic gut caudal to the cloaca." [http://medical-dictionary.thefreedictionary.com/gut]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: part_of XAO:0000092 ! archenteron
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000107
name: tail bud
namespace: xenopus_anatomy
def: "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25." [http://dictionary.reference.com/medical/tail+bud, ISBN:0815318960]
subset: frequent_anatomy_items
synonym: "tailbud" EXACT []
xref: UBERON:0002533
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000001 ! ectoderm
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000087 ! tail region
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000108
name: chordoneural hinge
namespace: xenopus_anatomy
def: "The anterior limit of the neurenteric canal, which connects the post-anal gut with the central canal of the spinal chord. It is formed from a population of cells derived from the dorsal lip of the late gastrula, and has been shown to be important in tail development." [ISBN:0762302852, PMID:11404094, PMID:7916680]
synonym: "chordo neural hinge" EXACT []
synonym: "CNH" EXACT []
xref: UBERON:0007097
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000107 ! tail bud
relationship: part_of XAO:0003204 ! neural tube
relationship: part_of XAO:0004057 ! tail tip
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000109
name: posterior wall of neurenteric canal
namespace: xenopus_anatomy
def: "Structure formed by the ventral movement of the proctodeum anlage, which results in the shifting of the circumblastoral collar lateral walls to the posterior end of the embryo." [PMID:7916680]
synonym: "posterior wall of NEC" EXACT []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000043 ! NF stage 27
relationship: part_of XAO:0005245 ! neurenteric canal
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000110
name: glomeral mesenchyme
namespace: xenopus_anatomy
def: "Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm." [ISBN:0815318960]
synonym: "corpuscle" RELATED []
synonym: "glomerulus" RELATED []
xref: UBERON:0007128
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0000111
name: germ cell
namespace: xenopus_anatomy
def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [XAO:curators]
synonym: "germ cells" EXACT PLURAL []
synonym: "germ line cell" RELATED []
synonym: "germ line cells" RELATED PLURAL []
xref: CL:0000586
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000113
name: embryo
namespace: xenopus_anatomy
def: "Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems." [BTO:0000379]
subset: frequent_anatomy_items
xref: UBERON:0000922
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: develops_from XAO:0000035 ! zygote
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0000114
name: artery
namespace: xenopus_anatomy
def: "Any of the tubular branching vessels that carry blood from the heart through the body." [http://www.merriam-webster.com/medlineplus/artery]
xref: UBERON:0001637
is_a: XAO:0001011 ! blood vessel
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000115
name: vein
namespace: xenopus_anatomy
def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [http://www.merriam-webster.com/medlineplus/vein]
xref: UBERON:0001638
is_a: XAO:0001011 ! blood vessel
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000116
name: capillary
namespace: xenopus_anatomy
def: "Any of the smallest blood vessels connecting arterioles with venules." [http://www.merriam-webster.com/medlineplus/capillary]
xref: UBERON:0001982
is_a: XAO:0001011 ! blood vessel
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000117
name: respiratory system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the organs involved in breathing in respiration (breathing)." [http://dictionary.reference.com/medical/respiratory+apparatus]
xref: UBERON:0001004
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000118
name: trachea
namespace: xenopus_anatomy
def: "An elongated tube that carries air to and from the lungs." [AAO:0010140]
xref: UBERON:0003126
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0005127 ! anterior foregut
relationship: part_of XAO:0000117 ! respiratory system
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000119
name: lung
namespace: xenopus_anatomy
def: "Either of two organs that allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air." [AAO:0010567]
xref: UBERON:0002048
is_a: XAO:0003034 ! viscus
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0005140 ! lung bud
relationship: part_of XAO:0000117 ! respiratory system
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000120
name: external gill
namespace: xenopus_anatomy
def: "The primary respiration organ in some species of tadpoles, whose function is the extraction of oxygen from water and the excretion of carbon dioxide. The microscopic structure of a gill is such that it presents a very large surface area to the external environment. Gills usually consist of thin filaments of tissue, branches, or slender tufted processes which have a highly folded surface to increase surface area. A high surface area is crucial for effective gas exchange." [XAO:curators]
synonym: "gill" BROAD []
xref: UBERON:0008891
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000448 ! gill primordium
relationship: end_stage XAO:1000065 ! NF stage 53
relationship: part_of XAO:0000117 ! respiratory system
relationship: start_stage XAO:1000051 ! NF stage 39

[Term]
id: XAO:0000121
name: bronchus
namespace: xenopus_anatomy
def: "A passage of airway in the respiratory tract that conducts air into the lungs." [XAO:curators]
synonym: "bronchial tube" EXACT []
xref: UBERON:0002185
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0000117 ! respiratory system
relationship: start_stage XAO:1000062 ! NF stage 50

[Term]
id: XAO:0000122
name: hematological system
namespace: xenopus_anatomy
def: "Anatomical system that consists of the blood and blood forming tissues." [http://dictionary.reference.com/medical/hematologic]
synonym: "haematological system" EXACT []
synonym: "haematopoietic system" EXACT []
synonym: "hematopoietic system" RELATED []
xref: UBERON:0002390
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000123
name: bone marrow
namespace: xenopus_anatomy
def: "Flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells." [UBERON:0002371]
xref: UBERON:0002371
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000010 ! juvenile frog stage

[Term]
id: XAO:0000124
name: blood
namespace: xenopus_anatomy
def: "The fluid that circulates in the heart, arteries, capillaries, and veins carrying nourishment and oxygen to and bringing away waste products from all parts of the animal." [http://www.merriam-webster.com/medlineplus/blood]
xref: UBERON:0000178
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0004001 ! portion of organism substance
relationship: develops_from XAO:0004144 ! anterior ventral blood island
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000125
name: alimentary system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [http://www.merriam-webster.com/medlineplus/alimentary+system]
synonym: "digestive system" RELATED []
synonym: "gut" RELATED []
xref: UBERON:0001007
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000126
name: oral cavity
namespace: xenopus_anatomy
def: "The cavity of the mouth, bounded by the jaw bones and associated structures." [VHOG:0000188, XAO:EJS]
xref: UBERON:0000167
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0000125 ! alimentary system
relationship: part_of XAO:0003029 ! mouth
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000127
name: esophagus
namespace: xenopus_anatomy
def: "Tube that connects the pharynx to the stomach. At NF stage 57 it is a straight tube, round in cross section, and starting from the pharynx runs backward along the dorsal side of the abdominal cavity. Its lining consists of a columnar glandular epithelium with mucus secreting cells. It is thrown into longitudinal folds." [http://dictionary.reference.com/medical/esophagus, ISBN:0815318960]
synonym: "oesophagus" EXACT []
xref: UBERON:0001043
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0005127 ! anterior foregut
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000128
name: stomach
namespace: xenopus_anatomy
def: "Internal organ that is the dilated portion of the alimentary tract situated between the esophagus and the beginning of the duodenum. It produces gastric juices involved in the breakdown of food." [http://dictionary.reference.com/medical/stomach]
xref: UBERON:0000945
is_a: XAO:0003034 ! viscus
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0004513 ! foregut endoderm
relationship: part_of XAO:0000232 ! foregut
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000129
name: intestine
namespace: xenopus_anatomy
def: "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter." [AAO:0000246]
xref: UBERON:0000160
is_a: XAO:0003034 ! viscus
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000130
name: small intestine
namespace: xenopus_anatomy
def: "A part of the alimentary system and principal organ of digestion, comprising the duodenum and ileum and characterized by longitudinal folds. In the tadpole it is a long simple tube with a single layer of cuboidal epithelial cells." [PMID:15738398]
xref: UBERON:0002108
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000103 ! midgut
relationship: part_of XAO:0000129 ! intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000131
name: large intestine
namespace: xenopus_anatomy
def: "A short, wide tube that is part of the alimentary system and comprises the colon and rectum and empties into the cloaca. It lacks longitudinal folds characteristic of the small intestine. It absorbs water and salts from the gut lumen." [PMID:21471667]
xref: UBERON:0000059
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000104 ! hindgut
relationship: part_of XAO:0000129 ! intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000132
name: liver and biliary system
namespace: xenopus_anatomy
def: "Anatomical system comprising the liver, gall bladder, and associated ducts." [XAO:EJS]
xref: UBERON:0002423
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000133
name: liver
namespace: xenopus_anatomy
def: "Organ that secretes bile and participates in formation of certain blood proteins. The liver is the largest internal organ, primarily consisting of hepatocytes, and has a wider variety of functions than any other organs in the body. The hepatocyte is a polarized epithelial cell that exhibits both endocrine and exocrine properties. The biliary epithelial cells (cholangiocytes), sinusoidal endothelial cells, hepatic stellate cells (Ito cells), Kupffer cells, and pit cells (liver-specific natural killer cells) represent the majority of non-hepatocyte cell types in the liver. During embryogenesis, the liver is generated in the ventral foregut endoderm." [AAO:0010111, PMID:17474120]
xref: UBERON:0002107
is_a: XAO:0003034 ! viscus
is_a: XAO:0003164 ! solid compound organ
relationship: develops_from XAO:0003266 ! liver primordium
relationship: part_of XAO:0000132 ! liver and biliary system
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000134
name: bile duct
namespace: xenopus_anatomy
def: "Duct that carries bile from the liver to the small intestine." [XAO:EJS, ZFA:0001100]
synonym: "hepatic duct" RELATED []
xref: UBERON:0002394
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: part_of XAO:0000132 ! liver and biliary system
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000135
name: gall bladder
namespace: xenopus_anatomy
def: "A small organ of the alimentary system that aids mainly in fat digestion, and concentrates bile that is produced by the liver." [XAO:EJS, ZFA:0000208]
synonym: "gallbladder" EXACT []
xref: UBERON:0002110
is_a: XAO:0003034 ! viscus
is_a: XAO:0003041 ! compound organ
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: develops_from XAO:0004205 ! gall bladder primordium
relationship: part_of XAO:0000132 ! liver and biliary system
relationship: part_of XAO:0000232 ! foregut
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000136
name: pancreas
namespace: xenopus_anatomy
def: "Internal gland organ with distinct tissues with different endocrine and exocrine functions. Its rudiment has three parts, one dorsal and two ventral primordia. The ventral can be first detected at NF stage 37/38. The dorsal is clearly segregated from the duodenal wall by NF stage 39. At NF stage 40 the right and left primordia have fused just above the gastro-duodenal vein. At NF stage 42 blood vessels penetrate into the crevices between the pancreatic acini making them more conspicuous." [ISBN:0815318960, ISBN:0881679860]
xref: UBERON:0001264
is_a: XAO:0003034 ! viscus
is_a: XAO:0003041 ! compound organ
relationship: develops_from XAO:0000467 ! dorsal pancreatic bud
relationship: develops_from XAO:0001103 ! ventral pancreatic bud
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000051 ! NF stage 39

[Term]
id: XAO:0000137
name: exocrine pancreas
namespace: xenopus_anatomy
def: "Pancreatic tissue composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion." [XAO:EJS, ZFA:0001249]
xref: UBERON:0000017
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000136 ! pancreas
relationship: start_stage XAO:1000051 ! NF stage 39

[Term]
id: XAO:0000138
name: mesentery
namespace: xenopus_anatomy
def: "A double layer of tissue composed of peritoneum that attaches the visceral organs to the body wall." [XAO:EJS, ZFA:0005129]
synonym: "mesenterium" RELATED []
xref: UBERON:0007826
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000139
name: peritoneum
namespace: xenopus_anatomy
def: "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium." [AAO:0010814]
xref: UBERON:0002358
is_a: XAO:0004466 ! serous membrane
relationship: part_of XAO:0000125 ! alimentary system

[Term]
id: XAO:0000140
name: urogenital system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [http://www.merriam-webster.com/medlineplus/genitourinary+tract]
xref: UBERON:0004122
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000141
name: mesonephric kidney
namespace: xenopus_anatomy
def: "A visceral organ which provides osmoregulation and waste excretion for tadpoles through adult stages in Xenopus. The mesonephros starts to develop at NF stage 39, then during feeding stage tadpoles through metamorphosis replaces the embryonic pronephros as it degenerates." [XAO:curators]
synonym: "adult kidney" RELATED []
synonym: "mesonephros" RELATED []
synonym: "opisthonephros" RELATED []
synonym: "urniere" RELATED []
synonym: "Wolffian body" RELATED []
xref: UBERON:0000080
is_a: XAO:0005244 ! adult kidney
relationship: part_of XAO:0003025 ! trunk

[Term]
id: XAO:0000142
name: genital system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the organs concerned with reproduction." [http://www.merriam-webster.com/medlineplus/genitourinary+tract]
synonym: "reproductive system" RELATED []
xref: UBERON:0000990
is_a: XAO:0003002 ! anatomical system
relationship: develops_from XAO:0000018 ! genital ridge
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000064 ! NF stage 52

[Term]
id: XAO:0000143
name: urinary system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine." [http://www.merriam-webster.com/medlineplus/genitourinary+tract]
xref: UBERON:0001008
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000144
name: ureter
namespace: xenopus_anatomy
def: "Anatomical structure consisting of a long narrow duct that carries urine from the kidney to the urinary bladder." [AAO:0010254]
xref: UBERON:0000056
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000143 ! urinary system
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000146
name: glomerulus
namespace: xenopus_anatomy
def: "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated." [AAO:0010388, XAO:curators]
synonym: "renal corpuscle" RELATED []
xref: UBERON:0005325
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000292 ! mesonephric nephron
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000148
name: mesonephric tubule
namespace: xenopus_anatomy
def: "Any of the excretory units of the mesonephros, which connect to the mesonephric collecting duct." [http://www.bionalogy.com/urinary_system.htm]
synonym: "renal tubule" RELATED []
xref: UBERON:0000083
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000292 ! mesonephric nephron
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000151
name: mesonephric collecting duct
namespace: xenopus_anatomy
def: "Duct that connects to the mesonephric nephrons and collects filtrate." [http://en.wikipedia.org/wiki/Collecting_duct_system]
synonym: "collecting duct" RELATED []
xref: UBERON:0005319
is_a: XAO:0004000 ! duct
relationship: part_of XAO:0000148 ! mesonephric tubule
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000153
name: urethra
namespace: xenopus_anatomy
def: "Anatomical structure consisting of a tube carries urine from the urinary bladder to the outside of the body." [XAO:EJS]
xref: UBERON:0000057
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000143 ! urinary system
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000154
name: bladder
namespace: xenopus_anatomy
def: "The organ that collects urine excreted by the kidneys before disposal by urination." [XAO:curators]
synonym: "urinary bladder" EXACT []
xref: UBERON:0001255
is_a: XAO:0003034 ! viscus
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0000143 ! urinary system
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0000155
name: male genitalia
namespace: xenopus_anatomy
def: "Anatomical system comprising the organs of the male reproductive system." [http://www.merriam-webster.com/medlineplus/genitalia]
synonym: "male genitals" RELATED PLURAL []
xref: UBERON:0000079
is_a: XAO:0000142 ! genital system
relationship: part_of XAO:0003006 ! male organism

[Term]
id: XAO:0000156
name: female genitalia
namespace: xenopus_anatomy
def: "Anatomical system comprising the organs of the female reproductive system." [http://www.merriam-webster.com/medlineplus/genitalia]
synonym: "female genitals" RELATED PLURAL []
xref: UBERON:0000474
is_a: XAO:0000142 ! genital system
relationship: part_of XAO:0003005 ! female organism

[Term]
id: XAO:0000157
name: testis
namespace: xenopus_anatomy
def: "Reproductive organ that produces and releases sperm." [XAO:curators]
synonym: "testes" RELATED PLURAL []
xref: UBERON:0000473
is_a: XAO:0003146 ! gonad
relationship: part_of XAO:0000155 ! male genitalia

[Term]
id: XAO:0000158
name: endocrine system
namespace: xenopus_anatomy
def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [http://www.merriam-webster.com/medlineplus/endocrine+system]
xref: UBERON:0000949
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0000159
name: islets of Langerhans
namespace: xenopus_anatomy
def: "Structure that is made up of islet cells that produce insulin, glucagon, and somatostatin." [UBERON:0000016]
synonym: "endocrine pancreas" RELATED []
xref: UBERON:0000006
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0001103 ! ventral pancreatic bud
relationship: part_of XAO:0000136 ! pancreas
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000160
name: pineal gland
namespace: xenopus_anatomy
def: "An unpaired glandular organ subdivision attached on the midline near the posterior and habenular commissures of the epithalamus." [UBERON:0001905]
synonym: "epiphysis" RELATED []
synonym: "pineal organ" RELATED []
xref: UBERON:0001905
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000014 ! midbrain
relationship: part_of XAO:0000158 ! endocrine system
relationship: part_of XAO:0003198 ! visual system
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000162
name: thyroid
namespace: xenopus_anatomy
def: "A two-lobed endocrine gland, located next to the trachea, and producing various hormones, such as triiodothyronine and calcitonin." [UBERON:0002046]
synonym: "thyroid gland" EXACT []
xref: UBERON:0002046
is_a: XAO:0003041 ! compound organ
relationship: develops_from XAO:0000444 ! thyroid primordium
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000163
name: thymus
namespace: xenopus_anatomy
def: "Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop." [http://www.merriam-webster.com/medlineplus/thymus]
xref: UBERON:0002370
is_a: XAO:0003041 ! compound organ
relationship: part_of XAO:0000158 ! endocrine system
relationship: part_of XAO:0003152 ! immune system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000164
name: adrenal gland
namespace: xenopus_anatomy
def: "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine." [UBERON:0002369]
xref: UBERON:0002369
is_a: XAO:0003164 ! solid compound organ
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0000165
name: adrenal cortex
namespace: xenopus_anatomy
def: "Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. The perimeter region of the adrenal gland, the site of steroid synthesis." [PMID:14061885, UBERON:0001235]
synonym: "interrenal tissue" RELATED []
xref: UBERON:0001235
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000164 ! adrenal gland
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0000166
name: adrenal medulla
namespace: xenopus_anatomy
def: "Part of the adrenal gland, located at the center of the gland and surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine, norepinephrine, and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons. Composed mainly of hormone-producing chromaffin cells, it is the principal site of the conversion of the amino acid tyrosine into the catecholamines adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine." [UBERON:0001236]
synonym: "chromaffin cells" RELATED []
xref: UBERON:0001236
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000319 ! trunk neural crest
relationship: part_of XAO:0000164 ! adrenal gland
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000167
name: parathyroid
namespace: xenopus_anatomy
alt_id: XAO:0000450
def: "An organ specialized for secretion of parathyroid hormone. It controls the amount of calcium in the blood and within the bones." [UBERON:0001132]
synonym: "epithelial body" RELATED []
synonym: "parathyroid gland" EXACT []
xref: UBERON:0001132
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000247 ! visceral pouch 2
relationship: develops_from XAO:0000447 ! branchial arch 1
relationship: develops_from XAO:0000452 ! ultimobranchial body
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000168
name: musculoskeletal system
namespace: xenopus_anatomy
def: "Anatomical system that provides locomotion and physical support to the organism." [XAO:curators]
xref: UBERON:0002204
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000169
name: bone tissue
namespace: xenopus_anatomy
def: "The hard form of connective tissue that constitutes the majority of the skeleton." [BTO:0000140]
synonym: "bone" RELATED []
xref: UBERON:0002481
is_a: XAO:0004038 ! skeletal tissue
relationship: part_of XAO:0004276 ! bone element
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000170
name: cartilage tissue
namespace: xenopus_anatomy
def: "A type of dense connective tissue that is composed of specialized cells, chondrocytes, that produce a large amount of extracellular matrix." [http://en.wikipedia.org/wiki/Cartilage]
synonym: "cartilage" RELATED []
xref: UBERON:0002418
is_a: XAO:0004038 ! skeletal tissue
relationship: part_of XAO:0004026 ! endoskeleton
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000171
name: joint
namespace: xenopus_anatomy
def: "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue." [XAO:EJS, ZFA:0001596]
synonym: "articulation" EXACT []
xref: UBERON:0000982
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004274 ! articular system
relationship: part_of XAO:0004313 ! joint region
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000172
name: muscle
namespace: xenopus_anatomy
def: "A body tissue consisting of long cells that contract when stimulated and produce motion." [BTO:0000887]
subset: frequent_anatomy_items
xref: UBERON:0001630
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004042 ! muscular system
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000173
name: tendon
namespace: xenopus_anatomy
alt_id: XAO:0000400
def: "A fibrous, strong, connective tissue that connects muscle to bone." [http://dictionary.reference.com/medical/tendon]
xref: UBERON:0000043
is_a: XAO:0004030 ! dense regular connective tissue
relationship: develops_from XAO:0000399 ! tendon fibroblast

[Term]
id: XAO:0000174
name: skeletal muscle
namespace: xenopus_anatomy
def: "A type of muscle used to create movement, by applying force to bones and joints. Usually attached to bones by tendons." [http://en.wikipedia.org/wiki/Skeletal_muscle]
xref: UBERON:0001134
is_a: XAO:0000172 ! muscle
relationship: develops_from XAO:0000314 ! trunk somite
relationship: develops_from XAO:0000315 ! myotome
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000175
name: smooth muscle
namespace: xenopus_anatomy
def: "Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers. Found within the walls of blood vessels, the alimentary tract, bladder, and reproductive tract." [AAO:0010244, XAO:curators]
synonym: "visceral muscle" RELATED []
xref: UBERON:0001135
is_a: XAO:0000172 ! muscle
relationship: develops_from XAO:0000311 ! lateral plate mesoderm

[Term]
id: XAO:0000176
name: dermal system
namespace: xenopus_anatomy
def: "Anatomical system that consists of the skin and its appendages." [http://dictionary.reference.com/medical/dermal+system]
xref: UBERON:0002416
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000177
name: nervous system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the brain and spinal cord, nerves, ganglia, and parts of the receptor organs and that receives and interprets stimuli and transmits impulses to the effector organs." [AAO:0000324]
subset: frequent_anatomy_items
xref: UBERON:0001016
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000178
name: peripheral nervous system
namespace: xenopus_anatomy
def: "One of the two major divisions of the nervous system. Its nerves connect the central nervous system with sensory organs, other organs, muscles, blood vessels and glands." [http://dictionary.reference.com/medical/peripheral+nervous+system]
synonym: "PNS" EXACT []
xref: UBERON:0000010
is_a: XAO:0000177 ! nervous system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000179
name: eye
namespace: xenopus_anatomy
def: "The organ of sight (visual apparatus), almost spherical in shape. At the end of development (NF stage 66) the eyes bulge out of their orbital capsules near the lateral edge of the dorsal side of the head." [ISBN:0815318960, XAO:curators]
subset: frequent_anatomy_items
synonym: "eyes" RELATED PLURAL []
xref: UBERON:0000019
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000228 ! optic vesicle
relationship: part_of XAO:0000215 ! central nervous system
relationship: part_of XAO:0003024 ! head
relationship: part_of XAO:0003198 ! visual system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000180
name: cornea
namespace: xenopus_anatomy
def: "The transparent front part of the eye that, together with the lens, refracts light." [http://en.wikipedia.org/wiki/Cornea]
xref: UBERON:0000964
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0004091 ! non-neural ectoderm
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000181
name: globe
namespace: xenopus_anatomy
def: "A general term for the whole eye, or eye ball, of an organism." [AAO:0010346]
synonym: "eye ball" EXACT []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000182
name: conjunctiva
namespace: xenopus_anatomy
def: "A clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera and lines the inside of the eyelids. It is made of epithelial tissue." [UBERON:0001811]
synonym: "conjunctivae" EXACT PLURAL []
synonym: "conjunctivas" EXACT PLURAL []
xref: UBERON:0001811
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000183
name: sclera
namespace: xenopus_anatomy
def: "The opaque, fibrous, protective, outer layer of the eye containing collagen and elastic fiber." [UBERON:0001773]
xref: UBERON:0001773
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000185
name: iris
namespace: xenopus_anatomy
def: "A membrane in the eye, responsible for controlling the amount of light reaching the retina." [UBERON:0001769]
xref: UBERON:0001769
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000228 ! optic vesicle
relationship: part_of XAO:0000179 ! eye
relationship: part_of XAO:0004529 ! uveal tract
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000186
name: ciliary body
namespace: xenopus_anatomy
def: "Circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [UBERON:0001775]
xref: UBERON:0001775
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000179 ! eye
relationship: part_of XAO:0004529 ! uveal tract
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000187
name: dorsolateral placode region
namespace: xenopus_anatomy
def: "Lateral neurogenic placode region positioned dorsally to the epibranchial placodes, and that includes the lateral line placodes, the otic placode and the trigeminal placode." [ISBN:0878933840, ZFA:0001310]
xref: UBERON:0003067
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000320 ! sensorial layer
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0000188
name: optic nerve
namespace: xenopus_anatomy
def: "Cranial nerve that is continuous with the layer of nerve cells on the inner surface of the eye. It exits the neurocranium via the large optic foramen and is covered by a fibrous connective tissue sheath. It transmits visual information from the retina to the brain." [ISBN:080184780X, UBERON:0000941]
synonym: "cranial nerve II" EXACT []
synonym: "ON" EXACT []
synonym: "opticus" EXACT []
xref: UBERON:0000941
is_a: XAO:0000429 ! cranial nerve
relationship: develops_from XAO:0000475 ! optic stalk
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000189
name: auditory apparatus
namespace: xenopus_anatomy
def: "The combination of structures that form the ear and function to transmit vibrations and permit hearing." [ISBN:0070179778]
synonym: "ear" BROAD []
xref: UBERON:0001690
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000006 ! otic vesicle
relationship: part_of XAO:0003195 ! vestibuloauditory system
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000190
name: tympanic disk
namespace: xenopus_anatomy
alt_id: XAO:0000212
def: "A flattened, roughly circular cartilage derived from the extrastapes. This thin membrane or integument is stretched over the cartilaginous tympanic annulus in a drum-like manner, and forms the outer ear, receiving airborne vibrations and functioning in hearing." [ISBN:0070179778, PMID:20953303]
synonym: "external ear" RELATED []
synonym: "tympanic disc" EXACT []
synonym: "tympanic membrane" RELATED []
synonym: "tympanum" RELATED []
xref: UBERON:0001691
is_a: XAO:0004013 ! cartilage element
relationship: part_of XAO:0000189 ! auditory apparatus
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000191
name: middle ear
namespace: xenopus_anatomy
def: "The air-filled cavity within the skull that lies between the outer ear and the inner ear." [UBERON:0001756]
synonym: "tympanic cavity" EXACT []
xref: UBERON:0001756
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000189 ! auditory apparatus
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000192
name: inner ear
namespace: xenopus_anatomy
alt_id: XAO:0000194
def: "Labyrinthine anatomical cluster that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation." [PMID:16217737]
synonym: "membranous labyrinth" EXACT []
xref: UBERON:0001846
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000189 ! auditory apparatus
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000193
name: osseous labyrinth
namespace: xenopus_anatomy
def: "Structure consisting of the vestibule, lagena, and semicircular canal, cavities that are hollowed out of the substance of the bone, and lined by periosteum. They contain a clear fluid, the perilymph, in which the membranous labyrinth is situated." [http://en.wikipedia.org/wiki/Bony_labyrinth]
synonym: "bony labyrinth" RELATED []
xref: UBERON:0001839
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000195
name: utricle
namespace: xenopus_anatomy
def: "Inner ear structure into which the semicircular ducts find their outlet. Along with the saccule, it is part of the balancing apparatus (membranous labyrinth) located within the vestibule of the osseous labyrinth." [http://en.wikipedia.org/wiki/Utricle_(ear)]
synonym: "utricular otolith" RELATED []
xref: UBERON:0001853
is_a: XAO:0000214 ! auditory ossicle

[Term]
id: XAO:0000196
name: sacculus
namespace: xenopus_anatomy
def: "A major structure of the inner ear, ventral to the utriculus. Two small pouches extend from it: the papilla basilaris, and the papilla amphibiorum. The sacculus functions in the detection of sound." [ISBN:0070179778]
synonym: "saccule" RELATED []
xref: UBERON:0001854
is_a: XAO:0000214 ! auditory ossicle

[Term]
id: XAO:0000197
name: lagena
namespace: xenopus_anatomy
def: "A vestibular structure of the inner ear consisting of a ventral diverticulum off of the sacculus." [ISBN:1402073755]
synonym: "cochlea" RELATED []
xref: UBERON:0001844
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000193 ! osseous labyrinth
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000198
name: semicircular canal
namespace: xenopus_anatomy
def: "Any of the three fluid-filled ducts that loop from the utriculus in the inner ear, and help detect movement and maintain balance." [ISBN:0070179778]
synonym: "semicircular canals" RELATED PLURAL []
synonym: "semicircular ducts" RELATED PLURAL []
xref: UBERON:0001840
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000193 ! osseous labyrinth
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000199
name: vestibule
namespace: xenopus_anatomy
def: "The small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear." [UBERON:0005236]
xref: UBERON:0005236
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000193 ! osseous labyrinth
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000200
name: animal blastomere
namespace: xenopus_anatomy
def: "Pigmented, smaller blastomere of the animal (upper) hemisphere of the cleaving embryo." [ISBN:0471209627]
synonym: "animal hemisphere blastomere" EXACT []
synonym: "micromere" RELATED []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003016 ! blastomere
relationship: develops_from XAO:0000202 ! animal hemisphere
relationship: part_of XAO:0000202 ! animal hemisphere
relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell)

[Term]
id: XAO:0000202
name: animal hemisphere
namespace: xenopus_anatomy
def: "Anatomical region that is pigmented (dark brown) and tends to have the uppermost orientation, as it contains the blastocoel and cells that contain only small amounts of yolk. The Xenopus egg is divided into two roughly equal halves: the animal and vegetal hemispheres." [XAO:curator]
xref: UBERON:0012284
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000021 ! NF stage 11
relationship: part_of XAO:0000113 ! embryo

[Term]
id: XAO:0000204
name: peripheral nerve
namespace: xenopus_anatomy
def: "Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors." [NCIt:Peripheral_Nerve]
xref: UBERON:0002003
is_a: XAO:0003047 ! nerve
relationship: part_of XAO:0005199 ! peripheral ganglion

[Term]
id: XAO:0000205
name: axial mesoderm
namespace: xenopus_anatomy
def: "A type of mesoderm that lies along the central axis, under the neural tube, and gives rise to the notochord." [XAO:curators]
synonym: "chordamesoderm" RELATED []
synonym: "chordomesoderm" RELATED []
xref: UBERON:0003068
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000050 ! mesoderm
relationship: develops_from XAO:0004406 ! presumptive axial mesoderm
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: start_stage XAO:1000033 ! NF stage 12.5

[Term]
id: XAO:0000206
name: blastocoel anlage
namespace: xenopus_anatomy
def: "The first appearance of the anatomical space that will become the blastocoel." [XAO:curators]
is_a: XAO:0003043 ! primordium
relationship: end_stage XAO:1000018 ! NF stage 8

[Term]
id: XAO:0000207
name: blastocoel roof
namespace: xenopus_anatomy
def: "The dorsal surface of the blastocoel, the cavity of the blastula." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000294 ! blastocoel

[Term]
id: XAO:0000208
name: blastopore
namespace: xenopus_anatomy
def: "The opening of the archenteron to the exterior, marking the point of origin of the archenteron and the caudal end of the embryo." [ISBN:0023771100]
xref: UBERON:0000100
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000090 ! endoderm
relationship: develops_from XAO:0000281 ! vegetal yolk mass
relationship: end_stage XAO:1000034 ! NF stage 18
relationship: part_of XAO:0000068 ! marginal zone
relationship: part_of XAO:0000281 ! vegetal yolk mass
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000209
name: ganglion
namespace: xenopus_anatomy
def: "A cluster of nervous tissue principally composed of neuronal cell bodies external to the central nervous system (CNS)." [UBERON:0000045]
synonym: "ganglia" RELATED PLURAL []
xref: UBERON:0000045
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000178 ! peripheral nervous system
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0000210
name: spinal ganglion
namespace: xenopus_anatomy
def: "Type of ganglion that is a condensation of sensory neurons on the dorsal root of each spinal nerve. There is one pair of spinal ganglia per myotome, with the spinal ganglia of the trunk region larger and more distinct from each other than those of the tail region." [PMID:17521450, XAO:curators]
synonym: "dorsal root ganglion" RELATED []
synonym: "spinal ganglia" RELATED PLURAL []
xref: UBERON:0000044
is_a: XAO:0000209 ! ganglion
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000211
name: sympathetic chain
namespace: xenopus_anatomy
def: "Either of the pair of ganglionated longitudinal cords of the sympathetic nervous system of which one is situated on each side of the spinal column." [http://www.merriam-webster.com/medical/sympathetic%20chain]
synonym: "sympathetic trunk" EXACT []
xref: UBERON:0000407
is_a: XAO:0003047 ! nerve
relationship: part_of XAO:0000178 ! peripheral nervous system

[Term]
id: XAO:0000213
name: auditory tube
namespace: xenopus_anatomy
def: "The narrow tube connecting the middle ear with the pharynx, through which air flows to equalize pressure on either side of the tympanic membrane." [ISBN:0070179778]
synonym: "eustachian tube" EXACT []
synonym: "pharyngotympanic tube" EXACT []
xref: UBERON:0002393
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000189 ! auditory apparatus
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000214
name: auditory ossicle
namespace: xenopus_anatomy
def: "Any of the three tiny bones of the inner ear (columella or stapes, the sacculus and the utriculus) suspended in the otic capsule." [ISBN:0070179778]
xref: UBERON:0001686
is_a: XAO:0004276 ! bone element
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000215
name: central nervous system
namespace: xenopus_anatomy
def: "The part of the nervous system that consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and that supervises and coordinates the activity of the entire nervous system." [http://www.merriam-webster.com/medlineplus/central+nervous+system]
synonym: "CNS" EXACT []
xref: UBERON:0001017
is_a: XAO:0000177 ! nervous system
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000217
name: dermis
namespace: xenopus_anatomy
def: "A layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, composed of two layers, the papillary and reticular dermis." [UBERON:0002067]
xref: UBERON:0002067
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000220 ! dermatome
relationship: part_of XAO:0000023 ! skin
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000218
name: appendage
namespace: xenopus_anatomy
def: "An internal or external body part or prolongation that projects from, and is attached to, an organ or the main body of an organism." [XAO:curators]
synonym: "appendages" RELATED PLURAL []
xref: UBERON:0000026
is_a: XAO:0003013 ! organism subdivision
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000220
name: dermatome
namespace: xenopus_anatomy
def: "Somitic compartment that is a precursor of dermis, the cells of which become arranged in a single layer that blankets the myotome, possibly continuously (unsegmented) across somites." [PMID:17313522]
xref: UBERON:0004016
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000396 ! head somite 1
relationship: develops_from XAO:0000403 ! head somite 2
relationship: develops_from XAO:0000404 ! head somite 3
relationship: develops_from XAO:0000405 ! head somite 4
relationship: develops_from XAO:0000406 ! trunk somite 1
relationship: develops_from XAO:0000407 ! trunk somite 2
relationship: develops_from XAO:0000408 ! trunk somite 3
relationship: develops_from XAO:0000409 ! trunk somite 4
relationship: develops_from XAO:0000410 ! trunk somite 5
relationship: develops_from XAO:0000411 ! trunk somite 6
relationship: develops_from XAO:0000412 ! trunk somite 7
relationship: develops_from XAO:0000416 ! trunk somite 8
relationship: develops_from XAO:0000417 ! trunk somite 9
relationship: develops_from XAO:0000418 ! trunk somite 10
relationship: develops_from XAO:0000419 ! trunk somite 11
relationship: develops_from XAO:0000420 ! trunk somite 12
relationship: develops_from XAO:0000421 ! trunk somite 13
relationship: develops_from XAO:0000422 ! tail somite 14
relationship: develops_from XAO:0000423 ! tail somite 15
relationship: develops_from XAO:0000424 ! tail somite 16
relationship: develops_from XAO:0000425 ! tail somite 17
relationship: develops_from XAO:0004528 ! tail somite 18
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0005080 ! dermomyotome
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000223
name: otic placode
namespace: xenopus_anatomy
def: "Invagination of thickened epithelium near the hindbrain that gives rise to a spherically shaped ear vesicle, including precursors of the sensory epithelia of the inner ear and neurons of cranial nerve VIII." [PMID:16217737]
synonym: "auditory placode" RELATED []
synonym: "ear" BROAD []
xref: UBERON:0003069
is_a: XAO:0004620 ! neurogenic placode
relationship: develops_from XAO:0004207 ! posterior placodal area
relationship: end_stage XAO:1000042 ! NF stage 26
relationship: part_of XAO:0003195 ! vestibuloauditory system
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000224
name: vegetal part, early involuting
namespace: xenopus_anatomy
def: "Vegetal portion of the marginal zone of the embryo that turns inside the embryo during involution." [http://worms.zoology.wisc.edu/frogs/glossary.html]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000074 ! involuting marginal zone
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000225
name: trigeminal placode
namespace: xenopus_anatomy
def: "The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24. The trigeminal placode gives rise to the sensory neurons of the ophthalmic and maxillomandibular lobes of cranial nerve V." [PMID:21452441, UBERON:0003070]
xref: UBERON:0003070
is_a: XAO:0004620 ! neurogenic placode
relationship: develops_from XAO:0000187 ! dorsolateral placode region
relationship: develops_from XAO:0004206 ! anterior placodal area
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000226
name: equatorial belt
namespace: xenopus_anatomy
def: "Equatorial zone of the zygote with which the plane of first cleavage aligns." [XAO:EJS]
is_a: XAO:0003040 ! tissue
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: part_of XAO:0000035 ! zygote
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0000227
name: eye primordium
namespace: xenopus_anatomy
def: "First trace of the future visual apparatus. The eye primordia forming antero-lateral evaginations of the closing neural tube are originally massive formations into which only a slit-shaped extension of the neural groove penetrates at NF stage 18. At NF stage 19 they clearly segregate from the anterior portion of the neural tube." [ISBN:0815318960]
synonym: "eye" BROAD []
synonym: "eye anlage" RELATED []
xref: UBERON:0003071
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0004090 ! optic field
relationship: end_stage XAO:1000034 ! NF stage 18
relationship: part_of XAO:0003198 ! visual system
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0000228
name: optic vesicle
namespace: xenopus_anatomy
def: "The evagination of neurectoderm, which has pinched off from the anterior neural keel, that precedes formation of the optic cup." [XAO:curators]
synonym: "eye" BROAD []
synonym: "eye vesicle" RELATED []
synonym: "optic cup" RELATED []
xref: UBERON:0004128
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000227 ! eye primordium
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: part_of XAO:0003198 ! visual system
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000229
name: fasciculated network of fibrils
namespace: xenopus_anatomy
def: "Randomly dispersed fibrils organized into criss-crossing fascicles or bundles in the coelomic envelope of oocytes." [PMID:2909400]
synonym: "coelomic envelope" BROAD []
is_a: XAO:0003040 ! tissue
is_a: XAO:0004005 ! extraembryonic structure
relationship: end_stage XAO:1000092 ! mature egg stage
relationship: part_of XAO:0000256 ! oocyte

[Term]
id: XAO:0000230
name: follicle cell
namespace: xenopus_anatomy
def: "Cell type that forms a layer within an ovarian follicle that surrounds the oocyte." [http://dictionary.reference.com/medical/follicle+cell]
xref: CL:0000477
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000258 ! ovary
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000231
name: follicle layer
namespace: xenopus_anatomy
def: "A monolayer of follicle cells surrounding the developing oocyte and forming adhesive contacts with the surrounding follicular epithelium." [PMID:619165]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000258 ! ovary
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000232
name: foregut
namespace: xenopus_anatomy
def: "The anterior part of the alimentary system, from the mouth and esophagus to the duodenum at the entrance of the bile duct. Structures of the foregut are: esophagus, stomach, duodenum, liver, gall bladder, and pancreas. The spleen is located in the foregut region, but is not a gut organ." [UBERON:0001041, XAO:curators]
xref: UBERON:0001041
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000092 ! archenteron
relationship: develops_from XAO:0004513 ! foregut endoderm
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000233
name: germ plasm
namespace: xenopus_anatomy
def: "A zone found in the cytoplasm of the egg cells that contains determinants that will give rise to the primordial germ cells. As the zygote undergoes mitotic divisions the germ plasm is ultimately restricted to a few cells of the embryo." [XAO:curators]
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000280 ! vegetal hemisphere

[Term]
id: XAO:0000234
name: germinal vesicle
namespace: xenopus_anatomy
def: "The nucleus of the oocyte, it is enclosed in a nuclear envelope and contains neucleoplasm, in which the chromosomes and extranucleoli are embedded. It breaks down as the oocyte matures, being no longer visible by the first meiotic metaphase." [XAO:curators]
synonym: "GV" EXACT []
is_a: XAO:0005038 ! nucleus
relationship: end_stage XAO:1000092 ! mature egg stage
relationship: part_of XAO:0000256 ! oocyte
relationship: start_stage XAO:1000088 ! oocyte stage VI

[Term]
id: XAO:0000235
name: cardiac mesoderm
namespace: xenopus_anatomy
def: "Two migratory heart primordia that move ventrally during the course of neurulation, and whose fusion begins at the ventral midline at NF stage 16." [XAO:curators]
synonym: "heart" BROAD []
xref: UBERON:0007005
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0005062 ! proepicardium
relationship: end_stage XAO:1000039 ! NF stage 23
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000236
name: duodenum
namespace: xenopus_anatomy
def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960]
xref: UBERON:0002114
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000130 ! small intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000237
name: ileum
namespace: xenopus_anatomy
def: "The final section of the small intestine." [UBERON:0002116]
xref: UBERON:0002116
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000130 ! small intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000238
name: rectum
namespace: xenopus_anatomy
def: "The terminal portion of the large intestine." [VHOG:0001751]
xref: UBERON:0001052
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000131 ! large intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000239
name: hepato-pancreatic duct
namespace: xenopus_anatomy
def: "The pancreatic duct and common bile duct together, which enter the descending duodenum." [XAO:curators]
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: part_of XAO:0000132 ! liver and biliary system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000240
name: lens placode
namespace: xenopus_anatomy
def: "A thickened portion of ectoderm that serves as the precursor to the lens. It invaginates to form the lens vesicle, which gives rise to the crystallin-accumulating cells of the transparent lens." [PMID:16677629, UBERON:0003073]
synonym: "lens" BROAD []
xref: UBERON:0003073
is_a: XAO:0004620 ! neurogenic placode
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0004206 ! anterior placodal area

[Term]
id: XAO:0000241
name: posterior cardinal vein
namespace: xenopus_anatomy
def: "Vein that returns blood from the trunk and drains into the duct of Cuvier via the pronephric sinus." [PMID:12606281]
synonym: "PCV" EXACT []
xref: UBERON:0002065
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000052 ! cardinal vein
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000242
name: mesonephric duct
namespace: xenopus_anatomy
def: "Duct that drains the mesonephros and connects it to the ureter." [XAO:EJS]
synonym: "Wolffian duct" RELATED []
xref: UBERON:0003074
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000063 ! pronephric duct
relationship: part_of XAO:0000141 ! mesonephric kidney
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000243
name: colon
namespace: xenopus_anatomy
def: "The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body." [UBERON:0001155]
synonym: "hindgut" BROAD []
synonym: "posterior intestine" RELATED []
xref: UBERON:0001155
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000131 ! large intestine
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000244
name: cloaca
namespace: xenopus_anatomy
def: "The posterior opening that serves as the common opening for the intestinal, reproductive, and urinary tracts, closed by the cloacal sphincter." [XAO:curators]
subset: frequent_anatomy_items
synonym: "cloacal chamber" RELATED []
synonym: "vent" RELATED []
xref: UBERON:0000162
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000107 ! tail bud
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000245
name: mitochondrial cloud
namespace: xenopus_anatomy
def: "A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material." [GO:0032019]
synonym: "Balbiani body" EXACT []
synonym: "MC" RELATED []
synonym: "mitochondrial aggregate" EXACT []
xref: GO:0032019
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000083 ! oocyte stage I
relationship: part_of XAO:0000256 ! oocyte

[Term]
id: XAO:0000246
name: myocoelic slit
namespace: xenopus_anatomy
def: "Space that separates the thicker inner sheet of splanchnic mesoderm from the thinner outer somatic mesoderm." [PMID:5449482]
is_a: XAO:0003190 ! anatomical space
relationship: end_stage XAO:1000034 ! NF stage 18
relationship: part_of XAO:0000315 ! myotome
relationship: start_stage XAO:1000026 ! NF stage 16

[Term]
id: XAO:0000247
name: visceral pouch 2
namespace: xenopus_anatomy
def: "Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634]
synonym: "second visceral pouch" EXACT []
xref: UBERON:0007123
is_a: XAO:0000282 ! visceral pouch

[Term]
id: XAO:0000248
name: neural groove
namespace: xenopus_anatomy
def: "The median dorsal longitudinal groove in the neural plate, directly above the notochord, which appears after neural fold formation." [http://www.merriam-webster.com/medlineplus/neural+groove, XAO:curators]
synonym: "median groove" RELATED []
synonym: "neural midline" RELATED []
xref: UBERON:0005061
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000042 ! neuroectoderm
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000249
name: neural plate
namespace: xenopus_anatomy
def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube. At NF stage 11.5 is the first indication of neural plate within the sensorial layer of ectoderm. It extends to near the animal pole by NF stage 12.5 and the entire plate is faintly delimited by NF stage 13." [http://dictionary.reference.com/medical/neural+plate, ISBN:0815318960]
xref: UBERON:0003075
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5

[Term]
id: XAO:0000250
name: posterior neural tube
namespace: xenopus_anatomy
def: "Posterior segment of the neural tube, which develops into the hindbrain and spinal cord." [XAO:EJS]
xref: UBERON:0003076
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000046 ! chordal neural plate
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0003204 ! neural tube
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000251
name: visceral pouch 3
namespace: xenopus_anatomy
def: "Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634]
synonym: "third visceral pouch" EXACT []
xref: UBERON:0007124
is_a: XAO:0000282 ! visceral pouch
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000252
name: neurocoel
namespace: xenopus_anatomy
def: "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [VHOG:0001119]
xref: UBERON:0003842
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000253
name: non-involuting marginal zone
namespace: xenopus_anatomy
def: "Animal portion of the marginal zone of the embryo that spreads in front of the animal cap but does not involute during gastrulation." [http://worms.zoology.wisc.edu/frogs/glossary.html]
synonym: "NIMZ" EXACT []
is_a: XAO:0000068 ! marginal zone
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000254
name: visceral pouch 4
namespace: xenopus_anatomy
def: "Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634]
synonym: "fourth visceral pouch" EXACT []
xref: UBERON:0007125
is_a: XAO:0000282 ! visceral pouch
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000255
name: visceral pouch 5
namespace: xenopus_anatomy
def: "Fifth of the pharyngeal (endodermal) evaginations between the visceral arches." [ISBN:0226557634]
synonym: "fifth visceral pouch" EXACT []
xref: UBERON:0007126
is_a: XAO:0000282 ! visceral pouch
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000256
name: oocyte
namespace: xenopus_anatomy
def: "The developing female gamete, the differentiation of which is classified into six stages: I (pre-vitellogenic), II (early vitellogenic), III (mid-vitellogenic, formation of pigment), IV (polarization along animal-vegetal axis), V (late vitellogenic), and VI (post-vitellogenic, appearance of equatorial band)." [PMID:4109871]
xref: CL:0000023
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0000268 ! secondary oogonium
relationship: end_stage XAO:1000092 ! mature egg stage

[Term]
id: XAO:0000257
name: oral evagination
namespace: xenopus_anatomy
def: "An outpocketing of the foregut ventral to the infundibulum and the hypophysis. The walls surrounding this cavity are composed of endoderm." [http://www.uoguelph.ca/zoology/devobio/34mmfrog/db34fg1.htm]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000232 ! foregut
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000258
name: ovary
namespace: xenopus_anatomy
def: "Either of paired female reproductive organs involved in production of ova and female sex hormones." [AAO:0000371]
xref: UBERON:0000992
is_a: XAO:0003146 ! gonad
relationship: part_of XAO:0000156 ! female genitalia

[Term]
id: XAO:0000259
name: paraxial mesoderm
namespace: xenopus_anatomy
def: "Area of mesoderm at either side of the midline embryonic notochord that, on segmentation, forms the paired somites." [http://dictionary.reference.com/medical/paraxial+mesoderm]
xref: UBERON:0003077
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0004134 ! presumptive paraxial mesoderm
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: part_of XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000024 ! NF stage 14

[Term]
id: XAO:0000260
name: perivitelline space
namespace: xenopus_anatomy
def: "The space between the zona pellucida and the cell membrane of an oocyte or fertilized ovum." [http://en.wikipedia.org/wiki/Perivitelline_space]
is_a: XAO:0004005 ! extraembryonic structure
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: part_of XAO:0000035 ! zygote
relationship: start_stage XAO:1000092 ! mature egg stage

[Term]
id: XAO:0000261
name: pigment layer
namespace: xenopus_anatomy
def: "Outer layer of the developing optic vesicle, which contains pigmented epithelium." [XAO:EJS]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: part_of XAO:0000228 ! optic vesicle
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000262
name: polar body
namespace: xenopus_anatomy
def: "A small cell formed by the meiotic division of an oocyte." [CL:0002090]
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000256 ! oocyte
relationship: end_stage XAO:1000088 ! oocyte stage VI

[Term]
id: XAO:0000263
name: primary oogonium
namespace: xenopus_anatomy
def: "A germ cell that is a primordial oocyte in a female and that develops into secondary oogonia by mitotic division." [XAO:EJS]
synonym: "primary oogonia" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0003149 ! primordial germ cell
relationship: part_of XAO:0000258 ! ovary
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000264
name: pronephric mesenchyme
namespace: xenopus_anatomy
def: "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30." [XAO:curators]
synonym: "pronephric anlage" RELATED []
synonym: "pronephric bulge" RELATED []
synonym: "pronephric primordium" RELATED []
xref: UBERON:0005721
is_a: XAO:0003046 ! mesenchyme
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0000265
name: visceral pouch 6
namespace: xenopus_anatomy
def: "Sixth of the pharyngeal (endodermal) evaginations between the visceral arches." [ISBN:0226557634]
synonym: "sixth visceral pouch" EXACT []
xref: UBERON:0007127
is_a: XAO:0000282 ! visceral pouch
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000266
name: retinal layer
namespace: xenopus_anatomy
def: "Inner layer of the developing optic vesicle, which contains retinal nerve cells." [XAO:EJS]
xref: UBERON:0001781
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: part_of XAO:0000228 ! optic vesicle
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000267
name: hypophyseal primordium
namespace: xenopus_anatomy
def: "The hypophyseal layer that separates from the stomodeal layer of the stomodeal-hypophyseal primordium at NF stage 29 and 30." [XAO:EJS]
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000268
name: secondary oogonium
namespace: xenopus_anatomy
def: "A type of germ cell that results from the mitotic division of a primary oogonium." [XAO:EJS]
synonym: "secondary oogonia" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0000263 ! primary oogonium
relationship: start_stage XAO:1000066 ! NF stage 54

[Term]
id: XAO:0000269
name: mouth primordium
namespace: xenopus_anatomy
def: "Anterior part of the embryonic alimentary canal that is formed as an invagination of the ectoderm and is the future mouth." [UBERON:0000930]
synonym: "mouth" BROAD []
synonym: "stomodeal-hypophyseal primordium" BROAD []
xref: UBERON:0000930
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium
relationship: end_stage XAO:1000072 ! NF stage 60
relationship: part_of XAO:0000001 ! ectoderm
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000270
name: sensorial layer of neurectoderm
namespace: xenopus_anatomy
def: "Deep layer of the neural ectoderm, which undergoes early neuronal differentiation." [PMID:11832243]
synonym: "deep layer of neurectoderm" RELATED []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000249 ! neural plate
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5

[Term]
id: XAO:0000271
name: somatic layer of lateral plate mesoderm
namespace: xenopus_anatomy
def: "Layer of lateral plate mesoderm that forms the future body wall; it underlies the ectoderm." [UBERON:0004871]
xref: UBERON:0004871
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000311 ! lateral plate mesoderm
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000026 ! NF stage 16

[Term]
id: XAO:0000272
name: Jacobson's organ
namespace: xenopus_anatomy
def: "An auxiliary olfactory sense organ involved in the detection of pheromones." [http://en.wikipedia.org/wiki/Vomeronasal_organ]
synonym: "organon vomeronasale" EXACT []
synonym: "VNO" EXACT []
synonym: "vomeronasal organ" EXACT []
xref: UBERON:0002255
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000273 ! olfactory organ
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000273
name: olfactory organ
namespace: xenopus_anatomy
def: "Organ comprising the specialized structures subserving the function of the sense of smell." [BTO:0001772]
xref: UBERON:0002268
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000005 ! olfactory placode
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000274
name: sperm entry point
namespace: xenopus_anatomy
def: "The point on the surface of the egg at which the sperm enters the egg." [XAO:EJS]
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: part_of XAO:0000035 ! zygote
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0000275
name: olfactory pit
namespace: xenopus_anatomy
alt_id: XAO:0004073
def: "A depression on the head of the embryo that becomes converted into a nasal passage." [http://www.merriam-webster.com/medical/olfactory%20pit]
synonym: "nasal pit" EXACT []
xref: UBERON:0005870
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000005 ! olfactory placode
relationship: end_stage XAO:1000062 ! NF stage 50
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000276
name: splanchnic layer of lateral plate mesoderm
namespace: xenopus_anatomy
alt_id: XAO:0004273
def: "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall; it overlies endoderm." [UBERON:0004872]
synonym: "splanchnic mesoderm" RELATED []
synonym: "visceral mesoderm" RELATED []
xref: UBERON:0004872
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000311 ! lateral plate mesoderm
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000026 ! NF stage 16

[Term]
id: XAO:0000277
name: choana
namespace: xenopus_anatomy
def: "The internal nasal passages, aperture or cavity in the roof of the buccopharynx." [ISBN:0226557634]
synonym: "choanae" RELATED PLURAL []
synonym: "internal nares" RELATED []
synonym: "posterior nasal apperture" EXACT []
xref: UBERON:0004771
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000005 ! olfactory placode
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000278
name: animal part, late involuting
namespace: xenopus_anatomy
def: "When the marginal zone mesoderm undergoes involution, where the marginal zone contacts the vegetal base." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000074 ! involuting marginal zone
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000279
name: vegetal blastomere
namespace: xenopus_anatomy
def: "Unpigmented, larger blastomere of the vegetal (lower) hemisphere of the cleaving embryo." [ISBN:0471209627]
synonym: "macromere" RELATED []
synonym: "vegetal hemisphere blastomere" EXACT []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003016 ! blastomere
relationship: develops_from XAO:0000280 ! vegetal hemisphere
relationship: part_of XAO:0000280 ! vegetal hemisphere
relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell)

[Term]
id: XAO:0000280
name: vegetal hemisphere
namespace: xenopus_anatomy
def: "Anatomical region that is the lower, light-colored hemisphere of the egg, as its cells contain large amounts of dense yolk proteins. The Xenopus egg is divided into two roughly equal halves: the animal and vegetal hemispheres." [XAO:curator]
xref: UBERON:0012285
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000021 ! NF stage 11
relationship: part_of XAO:0000113 ! embryo

[Term]
id: XAO:0000281
name: vegetal yolk mass
namespace: xenopus_anatomy
def: "Cell mass in the vegetal region of the embryo that will contribute to endoderm." [XAO:EJS]
synonym: "vegetal cell mass" EXACT []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000022 ! NF stage 12

[Term]
id: XAO:0000282
name: visceral pouch
namespace: xenopus_anatomy
def: "Pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634]
synonym: "visceral pouches" RELATED PLURAL []
xref: UBERON:0004117
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000232 ! foregut
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000283
name: pupil
namespace: xenopus_anatomy
def: "A hole located in the center of the iris of the eye that allows light to enter the retina." [http://en.wikipedia.org/wiki/Pupil]
xref: UBERON:0001771
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000284
name: epibranchial placode
namespace: xenopus_anatomy
def: "The three distinct placodal areas which develop from the posterior placodal area and lie ventral to the otic placode and dorsocaudal to the pharyngeal clefts, and contribute to the sensory ganglia for the distal portion of cranial nerves VII IX and X. The proximal neurons are derived from the neural crest." [ISBN:0878933840]
xref: UBERON:0003078
is_a: XAO:0004620 ! neurogenic placode
relationship: develops_from XAO:0000187 ! dorsolateral placode region
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: part_of XAO:0000178 ! peripheral nervous system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000285
name: pronephric nephron
namespace: xenopus_anatomy
def: "The structure that is the basic functional unit of the pronephros." [UBERON:0005309]
synonym: "pronephric tubule" RELATED []
xref: UBERON:0005309
is_a: XAO:0003037 ! multi-tissue structure
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0002000 ! pronephric kidney
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000286
name: late proximal tubule
namespace: xenopus_anatomy
def: "Portion of the pronephric tubule that is immediately posterior to the early proximal tubule and anterior to the early distal tubule." [PMID:15223337]
synonym: "late proximal segment" EXACT []
synonym: "proximal tubule 3" EXACT []
synonym: "proximal tubule segment 3" EXACT []
synonym: "PT3" EXACT []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004518 ! proximal tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000287
name: early distal tubule
namespace: xenopus_anatomy
def: "Portion of the pronephric tubule that is immediately posterior to the late proximal tubule and anterior to the late distal segment." [PMID:15223337]
synonym: "distal early tubule" EXACT []
synonym: "intermediate tubule" EXACT []
synonym: "intermediate tubule segment 1" EXACT []
synonym: "IT1" EXACT []
synonym: "pronephric distal early tubule" EXACT []
synonym: "pronephric early distal tubule" EXACT []
xref: UBERON:0006337
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004519 ! distal tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000288
name: early proximal tubule
namespace: xenopus_anatomy
def: "Portion of the pronephric tubule that is immediately anterior to the late proximal tubule." [PMID:15223337]
synonym: "proximal tubule 2" EXACT []
synonym: "proximal tubule segment 2" EXACT []
synonym: "PT2" EXACT []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004518 ! proximal tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000289
name: late distal tubule
namespace: xenopus_anatomy
def: "Pronephric segment immediately posterior to the early distal tubule and anterior to the pronephric duct." [PMID:15223337]
synonym: "distal tubule segment 1" EXACT []
synonym: "DT1" EXACT []
synonym: "late distal segment" EXACT []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004519 ! distal tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000291
name: mesonephric mesenchyme
namespace: xenopus_anatomy
def: "The tissue made up of loosely connected mesenchymal cells in the mesonephros." [UBERON:0005323]
xref: UBERON:0005323
is_a: XAO:0003046 ! mesenchyme
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000292
name: mesonephric nephron
namespace: xenopus_anatomy
alt_id: XAO:0000145
def: "The structure that is the basic functional unit of the adult or mesonephric kidney, consisting of the vascular loop of the glomerulus, the capsule, the nephrocoel, the nephric duct, the nephrostome and the nephric tubule." [ISBN:0521301521]
synonym: "nephron" RELATED []
xref: UBERON:0005322
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000291 ! mesonephric mesenchyme
relationship: part_of XAO:0000141 ! mesonephric kidney
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000293
name: neural fold (obsolete)
namespace: xenopus_anatomy
is_obsolete: true
replaced_by: XAO:0004087

[Term]
id: XAO:0000294
name: blastocoel
namespace: xenopus_anatomy
def: "The cavity of the blastula, a closed space that is invaded by early mesenchyme and later obliterated by the enlarging archenteron. It forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis." [ISBN:0023771100, ISBN:0815318960]
synonym: "blastocele" EXACT []
synonym: "blastocyst cavity" RELATED []
synonym: "cleavage cavity" RELATED []
synonym: "segmentation cavity" RELATED []
xref: UBERON:0000090
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000206 ! blastocoel anlage
relationship: end_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000295
name: central endoderm
namespace: xenopus_anatomy
def: "The portion of endoderm between dorsal and ventral blastopore lips, and extending towards to the blastocoel." [XAO:curators]
synonym: "endodermal yolk mass" RELATED []
synonym: "vegetal endodermal core" RELATED []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000026 ! NF stage 16
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5

[Term]
id: XAO:0000296
name: vegetal
namespace: xenopus_anatomy
def: "Anatomical direction relating to the vegetal pole or hemisphere." [XAO:EJS]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000297
name: animal
namespace: xenopus_anatomy
def: "Anatomical direction relating to the animal pole or hemisphere." [XAO:curators]
subset: anatomical_site_slim
synonym: "animal hemisphere" RELATED []
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000298
name: dorsal
namespace: xenopus_anatomy
def: "Spatial concept denoting the back or upper surface of the body." [NCIt:Dorsal]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000299
name: ventral
namespace: xenopus_anatomy
def: "Spatial concept denoting the underside or lower surface of the body." [NCIt:Ventral]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000300
name: superficial
namespace: xenopus_anatomy
def: "Spatial concept denoting only the surface of the body." [XAO:EJS]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000301
name: deep
namespace: xenopus_anatomy
def: "Spatial concept denoting extension relatively far inward." [NCIt:Deep]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000302
name: dorso-lateral
namespace: xenopus_anatomy
def: "Spatial concept pertaining to the back of the body and to the side." [http://medical-dictionary.thefreedictionary.com/dorsolateral]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000303
name: ventro-lateral
namespace: xenopus_anatomy
def: "Spatial concept pertaining to the part of the body opposite the back and away from the midline." [http://medical-dictionary.thefreedictionary.com/ventrolateral]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000304
name: lateral
namespace: xenopus_anatomy
def: "Spatial concept pertaining to being situated at or extending to the side." [NCIt:Lateral]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0000305
name: cranial placode
namespace: xenopus_anatomy
def: "A localized ectodermal thickening that develops by apicobasal elongation of cuboidal cells in the inner layer of the ectoderm in the head of the embryos, and is involved in formation of sense organs." [UBERON:0002546]
synonym: "cranial placodes" RELATED PLURAL []
xref: UBERON:0002546
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000037 ! animal cap inner layer
relationship: develops_from XAO:0000320 ! sensorial layer
relationship: develops_from XAO:0004104 ! neural plate border
relationship: end_stage XAO:1000054 ! NF stage 42
relationship: part_of XAO:0000042 ! neuroectoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000306
name: floor plate
namespace: xenopus_anatomy
def: "Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories." [PMID:15738958]
synonym: "floorplate" EXACT []
synonym: "spinal cord floor" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000047 ! notoplate
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000307
name: anterior neural tube
namespace: xenopus_anatomy
def: "Anterior segment of the neural tube, which develops into the forebrain and midbrain." [XAO:EJS]
xref: UBERON:0003080
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000045 ! pre-chordal neural plate
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0003204 ! neural tube
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000309
name: marginal zone (sensu neural)
namespace: xenopus_anatomy
def: "Region of the neural tube that will become the white matter of the nervous system." [ISBN:0393974308]
subset: anatomical_site_slim
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000310
name: anterior neural fold
namespace: xenopus_anatomy
def: "The anterior U-shaped portion of the neural folds, the two longitudinal dorsal ridges, caused by a folding up of the ectoderm, that make their appearance on either side of the middle line of the early neural embryo." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000045 ! pre-chordal neural plate
relationship: part_of XAO:0004087 ! neural fold
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000311
name: lateral plate mesoderm
namespace: xenopus_anatomy
def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures." [UBERON:0003081]
synonym: "LPM" EXACT []
xref: UBERON:0003081
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000050 ! mesoderm
relationship: part_of XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000033 ! NF stage 12.5

[Term]
id: XAO:0000313
name: head somite
namespace: xenopus_anatomy
def: "Any of the transient, degenerating somites that form in the occipital region of the animal." [XAO:curators]
synonym: "cranial somite" RELATED []
synonym: "occipital somite" RELATED []
xref: UBERON:0005594
is_a: XAO:0000058 ! somite
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0000040 ! head region

[Term]
id: XAO:0000314
name: trunk somite
namespace: xenopus_anatomy
def: "Any of the somites that are posterior to the head and anterior to the tail." [XAO:EJS]
xref: UBERON:0005598
is_a: XAO:0000058 ! somite
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0000315
name: myotome
namespace: xenopus_anatomy
def: "Somitic compartment that is a precursor of muscle." [PMID:17313522]
synonym: "myotomes" RELATED PLURAL []
xref: UBERON:0003082
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0005080 ! dermomyotome
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000316
name: epicardium
namespace: xenopus_anatomy
def: "The inner layer of the pericardium that is in contact with the surface of the heart. During cardiac development, it is the source of multipotent mesenchymal cells, which give rise to endothelial and smooth muscle cells in coronary vessels and also, possibly, to cardiomyocytes." [AAO:0010409, XAO:curators]
synonym: "heart epicardium" EXACT []
xref: UBERON:0002348
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000336 ! fused heart primordium
relationship: develops_from XAO:0004482 ! epicardial precursor cell
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000318
name: glomus
namespace: xenopus_anatomy
def: "Multi-tissue structure that is the filtration unit of the pronephric kidney. A glomus is a glomerulus that spans more than one body segment. It is the vascularized filter of the pronephric kidney. Blood is filtered through the glomus and the filtrate deposited into the coelom early in development, or the nephrocoel later in development. The glomus contains podocytes with well developed foot processes that are anatomically indistinguishable from the podocytes of adult glomeruli. The two glomera are linked via a narrow bridge called the glomeral nexus." [PMID:9268568, XAO:curators]
comment: Properly called a glomus as it extends over multiple body segments.
synonym: "corpuscle" RELATED []
synonym: "glomera" RELATED PLURAL []
synonym: "glomerulus" RELATED []
synonym: "renal corpuscle" RELATED []
xref: UBERON:0004739
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000110 ! glomeral mesenchyme
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0002000 ! pronephric kidney
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000319
name: trunk neural crest
namespace: xenopus_anatomy
def: "Neural crest cells that migrate along two major pathways: through the somites, to populate the skin where they give rise to pigment cells; cells migrating along the lateral pathway generate sensory and sympathetic ganglia and adrenal chromaffin cells, among others." [ISBN:0878933840]
synonym: "TNC" EXACT []
synonym: "trunk crest" RELATED []
xref: UBERON:0003083
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0000320
name: sensorial layer
namespace: xenopus_anatomy
def: "The inner layer of ectoderm." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0000323
name: profundus ganglion
namespace: xenopus_anatomy
def: "Type of ganglion that is separate distally from the trigeminal ganglia; they become fused at their proximal end as they condense." [PMID:21452441]
synonym: "cranial ganglion" RELATED []
synonym: "profundus ganglia" RELATED PLURAL []
is_a: XAO:0000209 ! ganglion
relationship: develops_from XAO:0004093 ! profundal placode
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000324
name: hypobranchial placode
namespace: xenopus_anatomy
def: "A unique type of neurogenic placode, located ventral and caudal to the 2nd and 3rd pharyngeal pouches, which gives rise to small hypobranchial ganglia of yet unknown function." [PMID:12712315]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000187 ! dorsolateral placode region
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000326
name: left spleen primordium
namespace: xenopus_anatomy
def: "Primordium of the spleen, which goes on to form the spleen proper, while the right splenic promordium degenerates." [XAO:curators]
synonym: "spleen" BROAD []
xref: UBERON:0006293
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0003152 ! immune system
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000327
name: right spleen primordium
namespace: xenopus_anatomy
def: "Transient splenic primordia that degenerates by NF stage 40." [XAO:curators]
synonym: "spleen" BROAD []
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm
relationship: part_of XAO:0003152 ! immune system
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000328
name: spleen
namespace: xenopus_anatomy
def: "Internal lymphoid organ the primary function of which is to filter blood." [XAO:EJS]
xref: UBERON:0002106
is_a: XAO:0003034 ! viscus
is_a: XAO:0003041 ! compound organ
relationship: develops_from XAO:0000326 ! left spleen primordium
relationship: develops_from XAO:0000327 ! right spleen primordium
relationship: part_of XAO:0003152 ! immune system
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000329
name: coelomic epithelium
namespace: xenopus_anatomy
def: "The epithelial lining of the coelom." [XAO:curators]
xref: UBERON:0005891
is_a: XAO:0003045 ! epithelium
relationship: develops_from XAO:0000271 ! somatic layer of lateral plate mesoderm
relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000330
name: Mullerian duct
namespace: xenopus_anatomy
def: "Transient developmental organ that gives rise to oviducts in females (and is documented to persist in some male frogs)." [AAO:0010141]
xref: UBERON:0003890
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000076 ! NF stage 64

[Term]
id: XAO:0000331
name: mesonephric early proximal tubule
namespace: xenopus_anatomy
def: "Structure that is equivalent to the convoluted proximal tubule of metanephric nephrons." [XAO:curators]
is_a: XAO:0000148 ! mesonephric tubule
relationship: develops_from XAO:0000292 ! mesonephric nephron

[Term]
id: XAO:0000332
name: mesonephric late proximal tubule
namespace: xenopus_anatomy
def: "Structure that is the mesonephros nephron's equivalent to the straight proximal segment of a metanephric nephron." [XAO:curators]
synonym: "opisthonephros" RELATED []
synonym: "proximal straight segment" RELATED []
is_a: XAO:0000148 ! mesonephric tubule
relationship: develops_from XAO:0000292 ! mesonephric nephron

[Term]
id: XAO:0000333
name: mesonephric early distal tubule
namespace: xenopus_anatomy
def: "The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons." [XAO:curators]
synonym: "ascending limb" RELATED []
synonym: "straight distal segment" RELATED []
xref: UBERON:0005892
is_a: XAO:0000148 ! mesonephric tubule
relationship: develops_from XAO:0000292 ! mesonephric nephron

[Term]
id: XAO:0000334
name: mesonephric late distal tubule
namespace: xenopus_anatomy
def: "The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons." [XAO:curators]
synonym: "mesonephric late distal segment" EXACT []
is_a: XAO:0000148 ! mesonephric tubule
relationship: develops_from XAO:0000292 ! mesonephric nephron

[Term]
id: XAO:0000336
name: fused heart primordium
namespace: xenopus_anatomy
def: "The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They give rise to the endocardium at NF stage 27/28." [XAO:curators]
synonym: "heart" BROAD []
synonym: "heart primordia" RELATED []
synonym: "heart primordium" RELATED []
xref: UBERON:0003084
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0004185 ! primary heart field
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0000337
name: endocardial tube
namespace: xenopus_anatomy
def: "Region in the embryo that consists of precursor cells for the development of the embryonic heart." [http://en.wikipedia.org/wiki/Endocardial_heart_tubes]
synonym: "heart tube" RELATED []
xref: UBERON:0004141
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000066 ! endocardium
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000338
name: ventral aorta
namespace: xenopus_anatomy
def: "The outlet of the embryonic heart; lies in the floor of the pharynx and conducts blood from the bulbus arteriosis to the aortic arches (1-6)." [ISBN:0023771100]
xref: UBERON:0003085
is_a: XAO:0003010 ! aorta
relationship: develops_from XAO:0000337 ! endocardial tube
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000339
name: left channel of ventral aorta
namespace: xenopus_anatomy
def: "Of the paired ventral aortas in the tadpole, the one that branches into the left aortic arches." [PMID:8928932]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000338 ! ventral aorta
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000340
name: right channel of ventral aorta
namespace: xenopus_anatomy
def: "Of the paired ventral aortas in the tadpole, the one that branches into the right aortic arches." [PMID:8928932]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000338 ! ventral aorta
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000341
name: aortic arch
namespace: xenopus_anatomy
def: "One of a series of six paired embryological vascular structures that give rise to several major arteries." [UBERON:0004363]
synonym: "aortic arches" RELATED PLURAL []
xref: UBERON:0004363
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000339 ! left channel of ventral aorta
relationship: develops_from XAO:0000340 ! right channel of ventral aorta
relationship: develops_from XAO:0004190 ! cardiac neural crest
relationship: end_stage XAO:1000078 ! NF stage 66

[Term]
id: XAO:0000342
name: aortic arch 1
namespace: xenopus_anatomy
def: "The anterior member of a series of six paired arterial connections between the dorsal and ventral aortae. Aortic arch that is part of mandibular arch." [XAO:curators]
synonym: "first aortic arch" EXACT []
xref: UBERON:0003118
is_a: XAO:0000341 ! aortic arch
relationship: end_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000343
name: aortic arch 2
namespace: xenopus_anatomy
def: "The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch that is part of hyoid arch." [ISBN:0023771100]
synonym: "second aortic arch" EXACT []
xref: UBERON:0003119
is_a: XAO:0000341 ! aortic arch
relationship: end_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000344
name: aortic arch 3
namespace: xenopus_anatomy
def: "The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult." [ISBN:0023771100]
synonym: "third aortic arch" EXACT []
xref: UBERON:0003120
is_a: XAO:0000341 ! aortic arch
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000345
name: external carotid artery
namespace: xenopus_anatomy
def: "Artery that arises from the ventral aorta and delivers blood to the filter apparatus. It is visible as a bilateral pair of vessels on the ventral surface of the head, running between the heart and the tip of the jaw." [ISBN:0073524239, PMID:12606281]
synonym: "ECA" EXACT []
xref: UBERON:0001070
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000338 ! ventral aorta
relationship: part_of XAO:0000439 ! filter chamber
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000349
name: larval aorta
namespace: xenopus_anatomy
def: "The aorta of a postembryonic, hatched or immature tadpole, prior to metamorphosis." [XAO:curators]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: develops_from XAO:0000344 ! aortic arch 3
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0000352
name: aortic arch 5
namespace: xenopus_anatomy
def: "The fifth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 5 artery is paired and has a common trunk with aortic arch 6 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. Aortic arches 5 and 6 supply the trunk and tail with oxygenated blood." [ISBN:0023771100]
synonym: "fifth aortic arch" EXACT []
xref: UBERON:0003122
is_a: XAO:0000341 ! aortic arch
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000353
name: aortic arch 6
namespace: xenopus_anatomy
def: "The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood." [ISBN:0023771100]
synonym: "sixth aortic arch" EXACT []
xref: UBERON:0003123
is_a: XAO:0000341 ! aortic arch
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000354
name: posterior palatine artery
namespace: xenopus_anatomy
def: "One of three branches of the internal carotid artery, the palatine artery supplies the mouth region." [PMID:12606281]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000342 ! aortic arch 1
relationship: part_of XAO:0000366 ! internal carotid artery
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000355
name: aortic arch 4
namespace: xenopus_anatomy
def: "The fourth in a series of paired arterial connections between the dorsal and ventral aortae, it lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult." [ISBN:0023771100]
synonym: "fourth aortic arch" EXACT []
synonym: "systemic arch" RELATED []
xref: UBERON:0003121
is_a: XAO:0000341 ! aortic arch
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000356
name: vascular endothelium
namespace: xenopus_anatomy
def: "Simple squamous epithelium that lines blood and lymphatic vessels and the heart." [XAO:EJS, ZFA:0001639]
synonym: "vascular endothelia" RELATED PLURAL []
xref: UBERON:0004852
is_a: XAO:0004010 ! simple squamous epithelium
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000357
name: arterial endothelium
namespace: xenopus_anatomy
def: "The thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall." [XAO:curators]
synonym: "endothelium of artery" RELATED []
xref: UBERON:0001917
is_a: XAO:0003045 ! epithelium
relationship: develops_from XAO:0000356 ! vascular endothelium
relationship: part_of XAO:0000114 ! artery
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000358
name: venous endothelium
namespace: xenopus_anatomy
def: "Simple squamous epithelium that lines the veins." [XAO:EJS]
xref: UBERON:0001919
is_a: XAO:0004010 ! simple squamous epithelium
relationship: develops_from XAO:0000356 ! vascular endothelium
relationship: part_of XAO:0000115 ! vein
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000361
name: arteria iliaca communis
namespace: xenopus_anatomy
def: "The blood vessel that bifurcates from the aorta, and supplies the abdominal and pelvic regions." [ISBN:0070179778]
synonym: "common iliac artery" EXACT []
xref: UBERON:0005609
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000061 ! NF stage 49

[Term]
id: XAO:0000362
name: coeliaco-mesenteric artery
namespace: xenopus_anatomy
def: "Artery consisting of many branches which supply blood to various organs in the viscus. One of the major blood vessels, branching off the dorsal aorta and supplying the embryonic foregut organs: liver, stomach, intestine, spleen and pancreas." [AAO:0010499, ISBN:0070179778]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000363
name: occipitovertebral artery
namespace: xenopus_anatomy
def: "One of paired arteries that extends dorsally from the systemic arch to supply the muscles of the jaw and back." [ISBN:0801836018]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000364
name: caudal artery
namespace: xenopus_anatomy
def: "The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis." [ISBN:0226557634]
synonym: "CA" EXACT []
xref: UBERON:0003086
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004151 ! tail vasculature

[Term]
id: XAO:0000365
name: arteria subclavia
namespace: xenopus_anatomy
def: "Artery that branches from either side of the dorsal aorta and delivers blood to the musculature of the shoulder region." [ISBN:0070179778]
synonym: "subclavian artery" EXACT []
xref: UBERON:0001533
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000363 ! occipitovertebral artery
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000064 ! NF stage 52

[Term]
id: XAO:0000366
name: internal carotid artery
namespace: xenopus_anatomy
def: "One of the major arteries of the head, it is the cranial continuation of the aortic arches and the dorsal aorta. It curves ventrally before resuming a dorsal course as it enters the head proper, and it lies ventral to the internal jugular vein. The internal carotid artery gives off palatine, ophthalmic, and cerebral branches by NF stage 41." [PMID:12606281]
synonym: "ICA" EXACT []
xref: UBERON:0001532
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000367
name: cerebral artery
namespace: xenopus_anatomy
def: "The anterior continuation of the internal carotid artery, which gives off the nasociliary artery anterior to the eye." [PMID:12606281]
xref: UBERON:0004449
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000366 ! internal carotid artery
relationship: part_of XAO:0000366 ! internal carotid artery
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000368
name: ophthalmic artery
namespace: xenopus_anatomy
def: "A branch of the internal carotid artery that delivers blood to the eye. Together with the opthalmic vein, it forms a double ring encircling the eye and retina. It enters the eye obliquely by crossing over the ophthalmic vein and the internal jugular vein." [PMID:12606281]
xref: UBERON:0001619
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0000366 ! internal carotid artery
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000369
name: anterior palatine artery
namespace: xenopus_anatomy
def: "One of three branches of the internal carotid artery, it supplies the mouth region." [PMID:12606281]
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000366 ! internal carotid artery
relationship: part_of XAO:0000366 ! internal carotid artery
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000370
name: arteria mesenterica posterior
namespace: xenopus_anatomy
def: "The artery that supplies the network of blood vessels (the mesentry) to the large intestine." [ISBN:0070179778]
synonym: "posterior mesenteric artery" EXACT []
xref: UBERON:0005616
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000361 ! arteria iliaca communis
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000062 ! NF stage 50

[Term]
id: XAO:0000371
name: right lymph heart
namespace: xenopus_anatomy
def: "The rightmost of the two bilaterally symmetrical lymph hearts that can be seen adjacent to somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43. Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system." [PMID:12606281, PMID:20067786]
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0003199 ! lymphatic system
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000372
name: left lymph heart
namespace: xenopus_anatomy
def: "The leftmost of the two lymph hearts, pulsatile organs that are present in lower vertebrates and function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43." [PMID:12606281, PMID:20067786]
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0003199 ! lymphatic system
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000373
name: duct of Cuvier
namespace: xenopus_anatomy
def: "Bilaterally paired longitudinal vein; the anterior cardinal returns blood from the head, and the posterior cardinal returns it from the trunk; these two vessels join together on each side as the common cardinal vein, also known as the duct of Cuvier that leads to the heart's sinus venosus." [XAO:EJS, ZFA:0000186]
synonym: "common cardinal vein" RELATED []
xref: UBERON:0002064
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium

[Term]
id: XAO:0000374
name: dorsal lymph space
namespace: xenopus_anatomy
def: "Large subdermal lymph-containing space located dorsally near the last vertebrae." [XAO:EJS]
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000371 ! right lymph heart
relationship: part_of XAO:0003199 ! lymphatic system
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000375
name: lymph vessel
namespace: xenopus_anatomy
def: "A vessel that contains or conveys lymph." [AAO:0011005]
synonym: "lymphatic vessel" RELATED []
xref: UBERON:0001473
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000372 ! left lymph heart
relationship: develops_from XAO:0000374 ! dorsal lymph space
relationship: part_of XAO:0001010 ! circulatory system
relationship: part_of XAO:0003199 ! lymphatic system
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000376
name: omphalomesenteric vein
namespace: xenopus_anatomy
def: "Any of the veins in the embryo that return blood from the yolk sac to the heart or later to the portal vein." [http://www.merriam-webster.com/medical/omphalomesenteric%20vein]
xref: UBERON:0005487
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000377
name: capillary system of liver
namespace: xenopus_anatomy
def: "The smallest of the blood vessels, parts of the microcirculation, of the liver." [XAO:curators]
synonym: "liver capillary" EXACT []
is_a: XAO:0000116 ! capillary
relationship: develops_from XAO:0000376 ! omphalomesenteric vein
relationship: part_of XAO:0000133 ! liver
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000378
name: musculoabdominal vein
namespace: xenopus_anatomy
def: "Ventrolateral component of the external jugular vein." [PMID:12606281]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000379
name: external jugular vein
namespace: xenopus_anatomy
def: "One of the bilateral pairs of vessels clearly seen on the ventral surface of the head, running between the heart and the tip of the jaw, and draining the filter apparatus. This vein is more developed by NF stage 45, when it crosses the head dorsolaterally to drain into the Duct of Cuvier and pronephric sinus." [PMID:12606281]
synonym: "external jugular" EXACT []
xref: UBERON:0001101
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000380
name: lateral postcardinal vein
namespace: xenopus_anatomy
def: "Vein that first appears as disconnected portions lateral to the Wolffian ducts at NF stage 44, gradually becoming continuous. They come into communication with the medial postcardinals at the kidney sinus." [ISBN:0815318960]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000381
name: mesonephric sinus
namespace: xenopus_anatomy
def: "Sinus that surrounds the mesonephric tubules and puts lateral and medial postcardinal veins into communication with each other." [ISBN:0815318960]
xref: UBERON:0006196
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000380 ! lateral postcardinal vein
relationship: part_of XAO:0000140 ! urogenital system
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0000382
name: internal jugular vein
namespace: xenopus_anatomy
def: "The main dorsal head vein, it drains into the Duct of Cuvier, and collects blood from the dorsal jaw region, cerebral veins, the ophthalmic vein and the short pharyngeal vein. It forms loop around the olfactory bulb by NF stage 43." [PMID:12606281]
xref: UBERON:0001586
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000383
name: anterior cardinal vein
namespace: xenopus_anatomy
def: "Vein that returns blood from the dorsal head and drains into the duct of Cuvier via the pronephric sinus." [PMID:12606281]
synonym: "ACV" EXACT []
xref: UBERON:0003087
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000052 ! cardinal vein

[Term]
id: XAO:0000384
name: medial cardinal vein
namespace: xenopus_anatomy
def: "Vein that gives rise to the interrenal vein and pronephric sinus." [XAO:EJS]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000052 ! cardinal vein
relationship: part_of XAO:0004423 ! trunk vasculature

[Term]
id: XAO:0000385
name: pronephric sinus
namespace: xenopus_anatomy
def: "A system of vessels that initially swell from where the anterior and posterior cardinal veins meet before draining into the heart via the duct of Cuvier at NF stage 33 and 34, and then continue to narrow and fold into a characteristic S-shape by NF stage 37 and 38. It continues to loop on itself, at first a loose, then a dense knot of many vessels by NF stage 45." [PMID:12606281]
xref: UBERON:0006174
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000373 ! duct of Cuvier
relationship: develops_from XAO:0000383 ! anterior cardinal vein
relationship: develops_from XAO:0000384 ! medial cardinal vein
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0002000 ! pronephric kidney
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0000386
name: interrenal vein
namespace: xenopus_anatomy
def: "Vein formed from fusion of the posterior cardinal veins and that extends caudally." [ISBN:0226557626]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000384 ! medial cardinal vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000387
name: hepatic vein
namespace: xenopus_anatomy
def: "Vein that carries blood away from the liver." [XAO:EJS, ZFA:0000670]
xref: UBERON:0001143
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0000125 ! alimentary system
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000388
name: posterior vena cava
namespace: xenopus_anatomy
def: "Vein that carries de-oxygenated blood from the posterior part of the body to the sinus venosus." [XAO:EJS]
xref: UBERON:0001072
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000386 ! interrenal vein
relationship: develops_from XAO:0000387 ! hepatic vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0000389
name: gastric vein
namespace: xenopus_anatomy
def: "One of the veins of the alimentary system. The subintestinal vein is on the right side of the gut and drains the gastric vein on its right side by NF stage 43. The gastric veins carry blood low in oxygen from the surface of the stomach, draining into the left omphalomesenteric vein." [ISBN:0226557634, PMID:12606281]
xref: UBERON:0004450
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0000125 ! alimentary system
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000390
name: caudal vein
namespace: xenopus_anatomy
def: "Vein in the tail returning blood from the trunk and tail to the heart, leading directly into the posterior cardinal vein in the posterior trunk." [XAO:curators]
synonym: "CV" EXACT []
xref: UBERON:0003088
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000386 ! interrenal vein
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004151 ! tail vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000391
name: subinterstitial vein
namespace: xenopus_anatomy
def: "Vein that carries away fluid in the interstitial spaces." [XAO:curators]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0000392
name: hepatic portal vein
namespace: xenopus_anatomy
def: "Vein that starts in capillaries of the alimentary canal and ends in capillaries of the liver." [XAO:EJS]
synonym: "portal vein" RELATED []
xref: UBERON:0002017
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0000125 ! alimentary system
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000393
name: tail vein
namespace: xenopus_anatomy
def: "Vein in the tail returning blood from the tail to the heart." [XAO:EJS, ZFA:0000180]
xref: UBERON:0003481
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004151 ! tail vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000394
name: pulmonary vein
namespace: xenopus_anatomy
def: "Any of the veins that collect blood from the lungs and some small vesicles received from the esophagus." [AAO:0010521]
xref: UBERON:0002016
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000395
name: medial abdominal vein
namespace: xenopus_anatomy
def: "Vein in the posterior region that drains the ventral abdominal wall." [ISBN:0815318960]
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000054 ! NF stage 42

[Term]
id: XAO:0000396
name: head somite 1
namespace: xenopus_anatomy
def: "Transient occipital somite that exists from NF stages 17 to 26 only." [XAO:curators]
synonym: "somite W" EXACT [PMID:2769206]
is_a: XAO:0000313 ! head somite
relationship: end_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0000397
name: sclerotome
namespace: xenopus_anatomy
def: "Somitic compartment that is a precursor of the axial skeleton." [XAO:curators]
synonym: "sclerotomes" RELATED PLURAL []
xref: UBERON:0003089
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000058 ! somite
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000399
name: tendon fibroblast
namespace: xenopus_anatomy
def: "An elongated fibroblast type cell, the cytoplasm of which is stretched between the collagen fibres of the tendon." [http://en.wikipedia.org/wiki/Tendon_cell]
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003017 ! fibroblast
relationship: develops_from XAO:0000397 ! sclerotome
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000401
name: sclerotomal cartilage
namespace: xenopus_anatomy
def: "Sclerotome cells of the cartilage fate." [XAO:EJS]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000397 ! sclerotome
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000397 ! sclerotome
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000403
name: head somite 2
namespace: xenopus_anatomy
def: "Transient occipital somite that exists from NF stages 18 to 29 only." [XAO:curators]
synonym: "somite X" EXACT [PMID:2769206]
is_a: XAO:0000313 ! head somite
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000404
name: head somite 3
namespace: xenopus_anatomy
def: "Transient occipital somite that exists from NF stages 18 to 29/30 only." [XAO:curators]
synonym: "somite Y" EXACT [PMID:2769206]
is_a: XAO:0000313 ! head somite
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000405
name: head somite 4
namespace: xenopus_anatomy
def: "Transient occipital somite that exists from NF stages 19 to late 30's." [XAO:curators]
synonym: "somite Z" EXACT [PMID:2769206]
is_a: XAO:0000313 ! head somite
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0000406
name: trunk somite 1
namespace: xenopus_anatomy
def: "Trunk somite that is initially the fifth somite, first forming around NF stage 19 and becoming more anteriorly positioned as the head somites degenerate. It is the most anterior somite by NF stage 45 and is adjacent to the otic vesicle." [ISBN:0815318960]
synonym: "fifth somite" RELATED []
synonym: "somite 1 " EXACT []
is_a: XAO:0000314 ! trunk somite

[Term]
id: XAO:0000407
name: trunk somite 2
namespace: xenopus_anatomy
def: "Trunk somite that is initially the sixth somite and later becomes the secondmost anterior somite." [ISBN:0815318960]
synonym: "sixth somite" RELATED []
synonym: "somite 2" EXACT []
is_a: XAO:0000314 ! trunk somite

[Term]
id: XAO:0000408
name: trunk somite 3
namespace: xenopus_anatomy
def: "The 1st somite located posterior to the head." [XAO:EJS]
synonym: "somite 3" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0000409
name: trunk somite 4
namespace: xenopus_anatomy
def: "The 2nd somite located posterior to the head." [XAO:EJS]
synonym: "somite 4" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0000410
name: trunk somite 5
namespace: xenopus_anatomy
def: "The 3rd somite located posterior to the head." [XAO:EJS]
synonym: "somite 5" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000411
name: trunk somite 6
namespace: xenopus_anatomy
def: "The 4th somite located posterior to the head." [XAO:EJS]
synonym: "somite 6" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0000412
name: trunk somite 7
namespace: xenopus_anatomy
def: "The 5th somite located posterior to the head." [XAO:EJS]
synonym: "somite 7" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000414
name: sclerotomal mesenchyme
namespace: xenopus_anatomy
def: "Mesenchymal cells that break from the sclerotome. Such cells migrate from the somite to surround the notochord." [ISBN:0123190606]
is_a: XAO:0003046 ! mesenchyme
relationship: develops_from XAO:0000397 ! sclerotome
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000397 ! sclerotome
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0000415
name: notochordal sheath
namespace: xenopus_anatomy
def: "Mesenchymal covering surrounding the notochord, derived from sclerotomal mesenchyme." [XAO:EJS]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000414 ! sclerotomal mesenchyme
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: part_of XAO:0000055 ! notochord
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000416
name: trunk somite 8
namespace: xenopus_anatomy
def: "The 6th somite located posterior to the head." [XAO:EJS]
synonym: "somite 8" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000417
name: trunk somite 9
namespace: xenopus_anatomy
def: "The 7th somite located posterior to the head." [XAO:EJS]
synonym: "somite 9" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0000418
name: trunk somite 10
namespace: xenopus_anatomy
def: "The 8th somite located posterior to the head." [XAO:EJS]
synonym: "somite 10" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000419
name: trunk somite 11
namespace: xenopus_anatomy
def: "The 9th somite located posterior to the head." [XAO:EJS]
synonym: "somite 11" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000420
name: trunk somite 12
namespace: xenopus_anatomy
def: "The 10th somite located posterior to the head." [XAO:EJS]
synonym: "somite 12" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0000421
name: trunk somite 13
namespace: xenopus_anatomy
def: "The 11th somite located posterior to the head." [XAO:EJS]
synonym: "somite 13" EXACT []
is_a: XAO:0000314 ! trunk somite
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0000422
name: tail somite 14
namespace: xenopus_anatomy
def: "The 12th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS]
synonym: "somite 14" EXACT []
synonym: "trunk somite 14" EXACT []
is_a: XAO:0003143 ! tail somite

[Term]
id: XAO:0000423
name: tail somite 15
namespace: xenopus_anatomy
def: "The 13th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS]
synonym: "somite 15" EXACT []
synonym: "trunk somite 15" EXACT []
is_a: XAO:0003143 ! tail somite
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000424
name: tail somite 16
namespace: xenopus_anatomy
def: "The 14th somite located posterior to the head. This somite forms at NF stage 28, by which time head somite 1 has degenerated, and it is resorbed at metamorphosis." [XAO:curators]
synonym: "somite 16" EXACT []
synonym: "trunk somite 16" EXACT []
is_a: XAO:0003143 ! tail somite
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000425
name: tail somite 17
namespace: xenopus_anatomy
def: "The 15th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS]
synonym: "somite 17" EXACT []
synonym: "trunk somite 17" EXACT []
is_a: XAO:0003143 ! tail somite
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000426
name: olfactory nerve
namespace: xenopus_anatomy
def: "Cranial nerve that supplies the nasal organ. It leaves the olfactory lobe, passes through the fenestra olfactoria into the nasal capsule, and there divides into the ramus profundus and ramus dorsalis." [ISBN:0471209627, ISBN:080184780X]
synonym: "cranial nerve I" EXACT []
xref: UBERON:0001579
is_a: XAO:0000429 ! cranial nerve
relationship: develops_from XAO:0000005 ! olfactory placode
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000427
name: gasserian ganglion
namespace: xenopus_anatomy
def: "Sensory ganglion of the trigeminal nerve." [http://en.wikipedia.org/wiki/Trigeminal_ganglion]
synonym: "gasserian ganglia" RELATED PLURAL []
xref: UBERON:0001675
is_a: XAO:0000209 ! ganglion
relationship: develops_from XAO:0000225 ! trigeminal placode
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000428
name: trigeminal ganglion
namespace: xenopus_anatomy
def: "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear." [UBERON:0001675]
synonym: "trigeminal ganglia" RELATED PLURAL []
synonym: "trigeminus ganglion" RELATED []
xref: UBERON:0001675
is_a: XAO:0000209 ! ganglion
relationship: develops_from XAO:0000225 ! trigeminal placode
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0000429
name: cranial nerve
namespace: xenopus_anatomy
alt_id: XAO:0003089
def: "Any of the major paired nerves of the head or cephalic region. Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. They are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves." [XAO:curators]
synonym: "cephalic nerve" RELATED []
synonym: "cranial nerves" RELATED []
xref: UBERON:0001785
is_a: XAO:0003047 ! nerve
relationship: part_of XAO:0000178 ! peripheral nervous system
relationship: part_of XAO:0003024 ! head

[Term]
id: XAO:0000430
name: Rathke's pouch
namespace: xenopus_anatomy
def: "A depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system." [UBERON:0005356]
xref: UBERON:0005356
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000269 ! mouth primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000269 ! mouth primordium
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000431
name: tooth
namespace: xenopus_anatomy
def: "Each of a set of hard, bony enamel-coated structures in the jaws, used for biting." [AEO:0000220]
synonym: "dentition" BROAD []
synonym: "teeth" RELATED PLURAL []
xref: UBERON:0001091
is_a: XAO:0004012 ! skeletal element
relationship: develops_from XAO:0000269 ! mouth primordium
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000072 ! NF stage 60

[Term]
id: XAO:0000437
name: death
namespace: xenopus_developmental_stage
def: "Xenopus developmental stage that corresponds to the end of the animal's life." [XAO:EJS]
xref: UBERON:0000071
is_a: XAO:1000000 ! Xenopus developmental stage
relationship: preceded_by XAO:1000095 ! post-embryonic stage

[Term]
id: XAO:0000439
name: filter chamber
namespace: xenopus_anatomy
def: "The structure that enables tadpoles, which are suspension feeders, to trap food particles. The palatoquadrate, ceratohyal and the connecting muscles are responsible for the irrigation and ventilation of the filter apparatus." [XAO:curators]
synonym: "coelom" RELATED []
synonym: "coelomic filter chamber" RELATED []
synonym: "filter apparatus" EXACT []
synonym: "peribranchial chamber" EXACT []
is_a: XAO:0003190 ! anatomical space
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0000440
name: lateral line placode
namespace: xenopus_anatomy
def: "Thickened placodal areas located anterior and posterior to the otic vesicle. There are 5 distinct lateral line placodes, each giving rise to a single lateral line nerve that will innervate lateral line hair cells and convey information on motion to the adjacent hindbrain." [ISBN:0878933840]
synonym: "lateral line" BROAD []
synonym: "lateral line placodes" RELATED PLURAL []
xref: UBERON:0009128
is_a: XAO:0004620 ! neurogenic placode
relationship: develops_from XAO:0004207 ! posterior placodal area
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: part_of XAO:0000095 ! lateral line system
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000441
name: infraorbital lateral line primordium
namespace: xenopus_anatomy
def: "Lateral line primordium that migrates ventrad along the posterior and ventral margin of the eye." [PMID:2652193]
is_a: XAO:0004411 ! lateral line primordium
relationship: develops_from XAO:0000440 ! lateral line placode
relationship: end_stage XAO:1000054 ! NF stage 42

[Term]
id: XAO:0000442
name: supraorbital lateral line
namespace: xenopus_anatomy
def: "Lateral line situated along the dorsal margin of the eye." [PMID:2652193]
xref: UBERON:0003090
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000440 ! lateral line placode

[Term]
id: XAO:0000443
name: trunk lateral line
namespace: xenopus_anatomy
def: "A lateral line that is present on the trunk of the organism." [XAO:EJS]
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000440 ! lateral line placode

[Term]
id: XAO:0000444
name: thyroid primordium
namespace: xenopus_anatomy
def: "The initial thyroid precursor, which arises from the ventral aspect of the second pharyngeal pouch." [UBERON:0003091]
synonym: "thyroid" BROAD []
xref: UBERON:0003091
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000105 ! pharyngeal cavity
relationship: end_stage XAO:1000054 ! NF stage 42
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000445
name: taste bud
namespace: xenopus_anatomy
def: "The organ used for chemoreception." [AAO:0010573]
xref: UBERON:0001727
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000105 ! pharyngeal cavity
relationship: develops_from XAO:0000446 ! tongue
relationship: part_of XAO:0003197 ! gustatory system
relationship: start_stage XAO:1000063 ! NF stage 51

[Term]
id: XAO:0000446
name: tongue
namespace: xenopus_anatomy
def: "The movable, muscular organ on the floor of the mouth." [UBERON:0001723]
xref: UBERON:0001723
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000097 ! mandibular arch
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000447
name: branchial arch 1
namespace: xenopus_anatomy
def: "The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, containing the first aortic arch." [ISBN:0023771100]
synonym: "first branchial arch" EXACT []
synonym: "third visceral arch" RELATED []
xref: UBERON:0003114
is_a: XAO:0000099 ! branchial arch
relationship: develops_from XAO:0000251 ! visceral pouch 3

[Term]
id: XAO:0000448
name: gill primordium
namespace: xenopus_anatomy
def: "A swelling from the 3rd visceral arch at NF stage 35 and 36, which co-occurs with a depression between the 3rd and 6th, forming the external gills by NF stage 39." [XAO:curators]
synonym: "external gill anlage" RELATED []
synonym: "gill" BROAD []
xref: UBERON:0008894
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000050 ! mesoderm
relationship: develops_from XAO:0000447 ! branchial arch 1
relationship: develops_from XAO:0000449 ! branchial arch 2
relationship: develops_from XAO:0004524 ! pharyngeal mesenchyme
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0000117 ! respiratory system
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000449
name: branchial arch 2
namespace: xenopus_anatomy
def: "The second pharyngeal/branchial arch; it arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature." [ISBN:0023771100]
synonym: "fourth visceral arch" RELATED []
synonym: "second branchial arch" EXACT []
xref: UBERON:0003115
is_a: XAO:0000099 ! branchial arch
relationship: develops_from XAO:0000254 ! visceral pouch 4
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0000451
name: branchial arch 3
namespace: xenopus_anatomy
def: "The third in a series of paired bars in the wall of the pharynx, within which are formed the third aortic arch and the cartilage bar of the visceral skeleton, and forms and supports the gills." [ISBN:0023771100]
synonym: "fifth visceral arch" RELATED []
synonym: "third branchial arch" EXACT []
xref: UBERON:0003116
is_a: XAO:0000099 ! branchial arch
relationship: develops_from XAO:0000255 ! visceral pouch 5
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000452
name: ultimobranchial body
namespace: xenopus_anatomy
def: "Anatomical structure that includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch." [AAO:0010547]
xref: UBERON:0003092
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000453 ! branchial arch 4
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000453
name: branchial arch 4
namespace: xenopus_anatomy
def: "The fourth in a series of paired bars in the wall of the pharynx, within which are formed the fourth aortic arch and the cartilage bar of the visceral skeleton; forms and supports the gills." [ISBN:0023771100]
synonym: "fourth branchial arch" EXACT []
synonym: "sixth visceral arch" RELATED []
xref: UBERON:0003117
is_a: XAO:0000099 ! branchial arch
relationship: develops_from XAO:0000265 ! visceral pouch 6
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000454
name: liver parenchyme
namespace: xenopus_anatomy
def: "The functional units of the liver including the lobules." [UBERON:0001280]
xref: UBERON:0001280
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: part_of XAO:0000133 ! liver
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000455
name: biliary tree
namespace: xenopus_anatomy
def: "Hollow tree organ, the organ parts of which consist of the bile ducts." [UBERON:0001173]
synonym: "biliary tract" RELATED []
xref: UBERON:0001173
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: part_of XAO:0000132 ! liver and biliary system
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0000457
name: pyloric sphincter
namespace: xenopus_anatomy
def: "Sphincter muscle that is part of the pyloric region of the stomach." [UBERON:0001202]
xref: UBERON:0001202
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0005130 ! distal stomach
relationship: part_of XAO:0005158 ! pylorus
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0000458
name: occipital lateral line
namespace: xenopus_anatomy
def: "A short lateral line that extends from the ear in a posterior-dorsal direction." [PMID:2652193]
xref: UBERON:0003093
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000440 ! lateral line placode
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0000459
name: infraorbital lateral line
namespace: xenopus_anatomy
def: "Lateral line situated along the posterior and ventral margin of the eye." [PMID:2652193]
xref: UBERON:0003094
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000460
name: hyomandibular lateral line
namespace: xenopus_anatomy
def: "Lateral line complex that radiates on the ventral side of the head from a point between the eye and the base of the larval tentacle." [PMID:2652193]
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0000461
name: trunk placode
namespace: xenopus_anatomy
def: "Thickened plate of ectoderm that contributes to the formation of the dorsal, middle, or ventral lateral line." [XAO:EJS]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000320 ! sensorial layer
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0000462
name: dorsal lateral line
namespace: xenopus_anatomy
def: "The dorsal-most part of the sensory system on the surface of the tadpole consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the tadpole through the water, as well as facilitating schooling, prey capture, and predator and obstacle avoidance." [XAO:curators]
xref: UBERON:0003095
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000461 ! trunk placode
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000463
name: middle lateral line
namespace: xenopus_anatomy
def: "A lateral line that extends from the ear in a posterior direction between the upper and lower lateral lines." [PMID:2652193]
xref: UBERON:0003096
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000461 ! trunk placode
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000464
name: ventral lateral line
namespace: xenopus_anatomy
def: "Ventrally located lateral line that runs over the abdomen." [XAO:EJS]
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000461 ! trunk placode
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0000465
name: caudal lateral line
namespace: xenopus_anatomy
def: "Cranial nerve of the caudal lateral line that enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines." [XAO:curators]
xref: UBERON:0006334
is_a: XAO:0004002 ! lateral line
relationship: develops_from XAO:0000464 ! ventral lateral line
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0000467
name: dorsal pancreatic bud
namespace: xenopus_anatomy
def: "The pancreatic bud that gives rise to the accessory pancreatic duct." [XAO:curators]
synonym: "pancreas" BROAD []
synonym: "primary pancreatic bud" EXACT []
xref: UBERON:0003923
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000103 ! midgut
relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000469
name: dorsal tail fin
namespace: xenopus_anatomy
def: "The dorsal part of the tail fin." [XAO:EJS]
xref: UBERON:0003097
is_a: XAO:0000002 ! fin
relationship: develops_from XAO:0000319 ! trunk neural crest
relationship: part_of XAO:0004062 ! tail fin
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0000470
name: unicellular gland
namespace: xenopus_anatomy
def: "Any of the large number of glands of the larval skin, particularly common in the fins and adjacent skin of the trunk; also formed in the former frontal gland area on the upper jaw." [ISBN:0815318960]
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000320 ! sensorial layer
relationship: end_stage XAO:1000010 ! juvenile frog stage
relationship: start_stage XAO:1000062 ! NF stage 50

[Term]
id: XAO:0000471
name: xanthophore
namespace: xenopus_anatomy
def: "A type of colored melanophore (mobile pigment cells of the dermis and epidermis) that contain fat-soluble carotenoids (obtained from the diet) and pteridines (synthesized from the cell) which are stored in pterinosomes. Their color depends on the pattern of carotenoids and pteridines. They are rarely found in pre-metamorphic larvae." [CL:0000430, ISBN:0226557634]
xref: CL:0000430
is_a: XAO:0003014 ! pigment cell
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0000472
name: iridophore
namespace: xenopus_anatomy
def: "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color." [AAO:0010318]
synonym: "guanophore" RELATED []
xref: CL:0000431
is_a: XAO:0003014 ! pigment cell
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0000474
name: choroid fissure
namespace: xenopus_anatomy
def: "A break in the continuity of the optic cup where the two sides of the cup meet." [ISBN:0815318960]
synonym: "optic fissure" RELATED []
synonym: "ventral choroidal fissure" RELATED []
xref: UBERON:0005412
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000228 ! optic vesicle
relationship: part_of XAO:0000179 ! eye
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0000475
name: optic stalk
namespace: xenopus_anatomy
def: "Neural tissue comprising the proximal part of either of the optic vesicles as they project towards the sides of the head; it remains narrow and constitutes the optic stalk (the peripheral part of each expands to form a hollow bulb)." [UBERON:0003098, XAO:curators]
xref: UBERON:0003098
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000228 ! optic vesicle
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0001001
name: cranial neural crest
namespace: xenopus_anatomy
def: "The most anterior of 5 distinct and partially overlapping functional domains of the premigratory neural crest, which are intially part of the neural epithelium. CNC cells migrate through the extracelluar matrix in 4 highly conserved streams: the mandibular crest, hyoid crest, anterior branchial crest and the posterior branchial crest." [XAO:curators]
synonym: "cephalic neural crest" RELATED []
synonym: "CNC" EXACT []
synonym: "head crest" RELATED []
xref: UBERON:0003099
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0001002
name: lung primordium
namespace: xenopus_anatomy
def: "Anterior endoderm that develops into the lung buds, and in turn, the lungs. A pair of lateral diverticula just over the liver rudiment is formed by the floor of the foregut just anterior to the liver diverticulum." [ISBN:0815318960, XAO:curators]
synonym: "lateral diverticula" RELATED []
synonym: "lung" BROAD []
xref: UBERON:0005597
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000117 ! respiratory system
relationship: part_of XAO:0000232 ! foregut
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0001010
name: circulatory system
namespace: xenopus_anatomy
def: "Anatomical system that has as its parts the blood and lymph vessels." [XAO:curators]
synonym: "vascular system" EXACT []
xref: UBERON:0004535
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0001011
name: blood vessel
namespace: xenopus_anatomy
def: "Any of the vessels through which blood circulates in the body." [BTO:0001102]
synonym: "blood vessels" RELATED PLURAL []
synonym: "vasculature" RELATED []
xref: UBERON:0001981
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: part_of XAO:0001010 ! circulatory system
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0001012
name: Stirnorgan
namespace: xenopus_anatomy
def: "Structure that is part of the pineal system, is located in the skin on the dorsal surface of the head, and is exposed continuously to ambient illumination." [DOI:10.1007/BF00663609]
synonym: "frontal organ" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000160 ! pineal gland
relationship: part_of XAO:0003198 ! visual system
relationship: start_stage XAO:1000054 ! NF stage 42

[Term]
id: XAO:0001013
name: musculature of face
namespace: xenopus_anatomy
def: "Muscle tissue forming the facial muscles, a group of striated muscles innervated by the facial nerves." [XAO:curators]
synonym: "facial muscle" EXACT []
synonym: "facial muscles" EXACT PLURAL []
xref: UBERON:0001577
is_a: XAO:0000172 ! muscle
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0001014
name: melanophore
namespace: xenopus_anatomy
def: "A pigment cell that contains melanin (a brownish-black pigment), is derived from the neural crest, and is patchily distributed in the epidermis of the tadpole." [XAO:CJZ]
comment: General convention refers to "melanophores" in lower vertebrates and "melonocytes" in amniotes but there is little if any difference between cell types.
synonym: "melanocyte" RELATED []
xref: CL:0000148
is_a: XAO:0003014 ! pigment cell
relationship: develops_from XAO:0004510 ! melanoblast
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0001015
name: rectal diverticulum
namespace: xenopus_anatomy
def: "Paired outgrowths of the cloaca that link the pronephric ducts to the exterior of the organism." [UBERON:0006172, XAO:curators]
synonym: "rectal diverticula" RELATED PLURAL []
xref: UBERON:0006172
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000244 ! cloaca
relationship: part_of XAO:0000143 ! urinary system
relationship: part_of XAO:0000244 ! cloaca
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0001016
name: abdominal myoblast
namespace: xenopus_anatomy
def: "The myoblast that forms the muscles of the anterior abdominal walls." [AAO:0010314]
synonym: "abdominal musculature" RELATED []
is_a: XAO:0003015 ! myoblast
relationship: part_of XAO:0000315 ! myotome
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0001017
name: connective tissue
namespace: xenopus_anatomy
def: "Portion of tissue that consists of mesodermally derived cells and intercellular matrix composed of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues." [XAO:EJS, ZFA:0001632]
synonym: "portion of connective tissue" EXACT []
xref: UBERON:0002384
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0001018
name: anterior lymph sac
namespace: xenopus_anatomy
def: "The protrusion of mesenchymal tissue of the anterior cardinal vein which forms lymph sacs." [PMID:17062017]
synonym: "rostral lymph sac" RELATED []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000358 ! venous endothelium
relationship: part_of XAO:0003199 ! lymphatic system
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0001019
name: proctodeum
namespace: xenopus_anatomy
def: "Inward fold on the surface of the embryonic ectoderm that develops into the common cloacal passage. The most posterior section of the larval alimentary system." [XAO:curators, ZFA:0000066]
synonym: "anus" RELATED []
synonym: "anus porus" RELATED []
synonym: "proctodaeum" EXACT []
synonym: "vent" RELATED []
xref: UBERON:0000931
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000001 ! ectoderm
relationship: develops_from XAO:0000082 ! circumblastoporal collar
relationship: develops_from XAO:0000208 ! blastopore
relationship: develops_from XAO:0004091 ! non-neural ectoderm
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0005230 ! larval alimentary system
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0001020
name: elastica externa
namespace: xenopus_anatomy
def: "Notochordal membrane covering derived from notochordal epithelium. Its first indication is at NF stage 24, and it is a distinct membrane by NF stage 28." [ISBN:0815318960]
synonym: "notochordal sheath" RELATED []
xref: UBERON:0013655
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000055 ! notochord
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0001021
name: notochordal epithelium
namespace: xenopus_anatomy
def: "Outer layer of cells of the differentiating notochord, which give rise to the elastica externa and interna." [http://dev.biologists.org/content/1/4/411.abstract]
is_a: XAO:0003045 ! epithelium
relationship: develops_from XAO:0000055 ! notochord
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0001101
name: first pancreatic bud
namespace: xenopus_anatomy
def: "One of two pancreatic primordia that give rise to a ventral pancreatic bud." [XAO:EJS]
synonym: "pancreas" BROAD []
xref: UBERON:0003921
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000232 ! foregut
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0001102
name: second pancreatic bud
namespace: xenopus_anatomy
def: "Second of two pancreatic primordia that give rise to a ventral pancreatic bud." [XAO:EJS]
synonym: "pancreas" BROAD []
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000232 ! foregut
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0001103
name: ventral pancreatic bud
namespace: xenopus_anatomy
def: "Either of the two ventral pancreas rudiments that join and fuse with the right end of the dorsal pancreatic rudiment." [ISBN:0815318960]
synonym: "pancreas" BROAD []
xref: UBERON:0003924
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0001101 ! first pancreatic bud
relationship: develops_from XAO:0001102 ! second pancreatic bud
relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell
relationship: end_stage XAO:1000057 ! NF stage 45
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0002000
name: pronephric kidney
namespace: xenopus_anatomy
def: "Transient embryonic organ that serves as a kidney, providing osmoregulation during early developmental stages, and then degenerates during metamorphosis (starting at NF stage 53) as the mesonephric kidney develops and becomes functional." [XAO:curators]
subset: frequent_anatomy_items
synonym: "head kidney" RELATED []
synonym: "pronephros" RELATED []
synonym: "vorniere" RELATED []
xref: UBERON:0002120
is_a: XAO:0003037 ! multi-tissue structure
is_a: XAO:0005243 ! embryonic kidney
relationship: develops_from XAO:0000264 ! pronephric mesenchyme
relationship: part_of XAO:0004521 ! coelom

[Term]
id: XAO:0003000
name: anatomical structure
namespace: xenopus_anatomy
def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003]
xref: CARO:0000003
xref: UBERON:0000061
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: end_stage XAO:0000437 ! death
relationship: start_stage XAO:1000083 ! oocyte stage I

[Term]
id: XAO:0003001
name: anatomical group
namespace: xenopus_anatomy
def: "Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue." [CARO:0000054]
xref: CARO:0000054
xref: UBERON:0000480
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003000 ! anatomical structure
relationship: develops_from XAO:0000113 ! embryo
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0003002
name: anatomical system
namespace: xenopus_anatomy
def: "Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity." [CARO:0000011]
xref: CARO:0000011
xref: UBERON:0000467
is_a: XAO:0003001 ! anatomical group

[Term]
id: XAO:0003003
name: unspecified
namespace: xenopus_anatomy
def: "Unspecified Xenopus anatomical entity." [XAO:EJS]
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: end_stage XAO:0000437 ! death
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0003004
name: whole organism
namespace: xenopus_anatomy
def: "Anatomical structure that is an individual member of Xenopus laevis." [CARO:0000012]
subset: organism_views
subset: sectional_anatomy_items
synonym: "ubiquitous" BROAD []
xref: CARO:0000012
xref: UBERON:0000468
is_a: XAO:0003000 ! anatomical structure
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0003005
name: female organism
namespace: xenopus_anatomy
def: "Gonochoristic organism that can produce female gametes." [CARO:0000028]
xref: CARO:0000028
xref: UBERON:0003100
is_a: XAO:0003004 ! whole organism

[Term]
id: XAO:0003006
name: male organism
namespace: xenopus_anatomy
def: "Gonochoristic organism that can produce male gametes." [CARO:0000027]
xref: CARO:0000027
xref: UBERON:0003101
is_a: XAO:0003004 ! whole organism

[Term]
id: XAO:0003007
name: anatomical entity in vitro
namespace: xenopus_anatomy_in_vitro
def: "An experimentally manipulated tissue or portion of the developing embryo, that can be culture alone (in vitro)." [XAO:curators]
is_a: XAO:0000000 ! Xenopus anatomical entity

[Term]
id: XAO:0003008
name: activin-induced ectoderm
namespace: xenopus_anatomy_in_vitro
def: "Ectoderm section that has been dissected from the embryo, and treated with activin, and maintained in vitro." [PMID:14061885]
is_a: XAO:0003007 ! anatomical entity in vitro

[Term]
id: XAO:0003009
name: disaggregated/reaggregated ectoderm treated with activin
namespace: xenopus_anatomy_in_vitro
def: "NF stage 8 ectoderm of Xenopus laevis embryos that have been cut and disaggregated. The cells have been treated with activin at a concentration to induce endodermal tissue. Afterwards the reaggregated cells have been cultured until control sibling embryos reach stage 12/13." [http://www.ncbi.nlm.nih.gov/UniGene/library.cgi?ORG=Xl&LID=1962]
is_a: XAO:0003007 ! anatomical entity in vitro

[Term]
id: XAO:0003010
name: aorta
namespace: xenopus_anatomy
def: "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs." [AAO:0010213]
xref: UBERON:0000947
is_a: XAO:0000114 ! artery

[Term]
id: XAO:0003011
name: primary germ layer
namespace: xenopus_anatomy
def: "A layer of cells produced during the process of gastrulation during the early development of the embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The types of germ layers are the endoderm, ectoderm, and mesoderm." [BTO:0000556]
synonym: "embryonic germ layer" RELATED []
synonym: "germ layer" RELATED []
xref: UBERON:0000923
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000113 ! embryo
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0003012
name: cell
namespace: xenopus_anatomy
def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:0000000]
xref: CARO:0000013
xref: CL:0000000
xref: GO:0005623
is_a: XAO:0003000 ! anatomical structure
relationship: part_of XAO:0003004 ! whole organism

[Term]
id: XAO:0003013
name: organism subdivision
namespace: xenopus_anatomy
def: "Anatomical structure that is a primary subdivision of the whole organism." [CARO:0000032]
synonym: "body part" RELATED []
xref: CARO:0000032
xref: UBERON:0000475
is_a: XAO:0005002 ! multicellular anatomical structure
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0003014
name: pigment cell
namespace: xenopus_anatomy
def: "Cell type that contains a deposition of coloring matter, the first of which differentiate during late tailbud stage, and that by NF stage 56 has produced a fully differentiated larval pigmentation pattern." [http://www.merriam-webster.com/medlineplus/pigment+cell, ISBN:0815318960]
synonym: "chromatophore" RELATED []
xref: CL:0000147
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000319 ! trunk neural crest
relationship: part_of XAO:0000023 ! skin
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0003015
name: myoblast
namespace: xenopus_anatomy
def: "Embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm." [CL:0000056]
xref: CL:0000056
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003016
name: blastomere
namespace: xenopus_anatomy
alt_id: XAO:0003243
def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [CL:0000353]
synonym: "blastoderm cell" EXACT []
xref: CL:0000353
is_a: XAO:0003241 ! early embryonic cell
relationship: end_stage XAO:1000017 ! NF stage 7
relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell)

[Term]
id: XAO:0003017
name: fibroblast
namespace: xenopus_anatomy
def: "A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057]
synonym: "keratocyte" RELATED []
xref: CL:0000057
is_a: XAO:0003255 ! mesodermal cell

[Term]
id: XAO:0003018
name: primary spermatogonium
namespace: xenopus_anatomy
def: "A germ cell that is a primordial spermatocyte in a male and that develops into secondary spermatogonia by mitotic division." [ISSN:0289-0003]
synonym: "primary spermatogonia" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0003149 ! primordial germ cell
relationship: part_of XAO:0000157 ! testis
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0003019
name: spermatocyte
namespace: xenopus_anatomy
def: "The developing male gamete." [XAO:curators]
xref: CL:0000017
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0003020 ! secondary spermatogonium
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0003020
name: secondary spermatogonium
namespace: xenopus_anatomy
def: "A type of germ cell that results from the mitotic division of a primary spermatogonium." [ISSN:0289-0003]
synonym: "secondary spermatogonia" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0003018 ! primary spermatogonium
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0003022
name: Rohon-Beard neuron
namespace: xenopus_anatomy
def: "Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. It first appears in trunk levels at NF stage 33/34, and at NF stage 35/36 has somas that are the largest in the spinal cord. It forms a nearly continuous double row of cells along the cord's medial dorsal surface and contributes ascending and descending axons to the dorsal tract. It appears well back in the tail by NF stage 39, begins to decline at NF stage 50 and is few in number, with pycnotic nuclei, at NF stage 55." [ISBN:0815318960, PMID:17506218]
synonym: "Rohon Beard cell" RELATED []
xref: CL:0000247
is_a: XAO:0003023 ! neuron
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0000249 ! neural plate

[Term]
id: XAO:0003023
name: neuron
namespace: xenopus_anatomy
def: "Cell that is the basic unit of nervous tissue, each consisting of a body, an axon, and dendrites, and the purpose of which is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540]
synonym: "nerve cell" RELATED []
xref: CL:0000540
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0004272 ! migrating neuroblast
relationship: part_of XAO:0000177 ! nervous system
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0003024
name: head
namespace: xenopus_anatomy
def: "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions." [AAO:0010335]
subset: frequent_anatomy_items
subset: organism_views
xref: UBERON:0000033
is_a: XAO:0003013 ! organism subdivision
relationship: part_of XAO:0000040 ! head region

[Term]
id: XAO:0003025
name: trunk
namespace: xenopus_anatomy
def: "Organism subdivision that is the part of the body posterior to the head and anterior to the tail." [XAO:EJS, ZFA:0001115]
subset: organism_views
xref: UBERON:0002100
is_a: XAO:0003013 ! organism subdivision
relationship: part_of XAO:0000054 ! trunk region
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003026
name: tail
namespace: xenopus_anatomy
def: "Organism subdivision that is the terminal, flexible posterior appendage of the larva. It is resorbed during metamorphosis beginning with degeneration of the notochord's distal tip at NF stage 61, followed by degeneration gradually extending to its more proximal regions and reaching its proximal end by NF stage 62. By NF stage 66 it exists only as a small dorsal swelling." [http://dictionary.reference.com/medical/tail, ISBN:0471209627]
subset: organism_views
xref: UBERON:0007812
is_a: XAO:0003013 ! organism subdivision
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000087 ! tail region
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003027
name: limb
namespace: xenopus_anatomy
def: "Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation." [XAO:curators]
xref: UBERON:0002101
is_a: XAO:0003013 ! organism subdivision
relationship: develops_from XAO:0003161 ! limb bud
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003028
name: surface structure
namespace: xenopus_anatomy
def: "Organism subdivision that is the collection of anatomical structures on the body surface." [XAO:EJS, ZFA:0000292]
xref: UBERON:0003102
is_a: XAO:0003013 ! organism subdivision

[Term]
id: XAO:0003029
name: mouth
namespace: xenopus_anatomy
def: "Cavity in which food is initially ingested and generally contains teeth, tongue and glands." [AAO:0010355]
xref: UBERON:0000165
is_a: XAO:0003190 ! anatomical space
relationship: develops_from XAO:0000269 ! mouth primordium
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0003030
name: forelimb
namespace: xenopus_anatomy
def: "One of the pair of limbs that are situated anteriorly, develop in sacs that separate them from the gill chamber, are well-defined buds by NF stage 48, are innervated by NF stage 51, and are ossified by NF stage 59." [BTO:0001729, ISBN:0471209627]
synonym: "anterior limb" EXACT []
synonym: "fore limb" EXACT []
xref: UBERON:0002102
is_a: XAO:0003027 ! limb
relationship: develops_from XAO:0003065 ! forelimb bud
relationship: part_of XAO:0004284 ! pectoral appendage

[Term]
id: XAO:0003031
name: hindlimb
namespace: xenopus_anatomy
def: "One of the pair of limbs that are situated posteriorly, are evident as buds laterally by NF stage 47, and are innervated by NF stage 51." [ISBN:0471209627]
synonym: "hind limb" EXACT []
synonym: "posterior limb" EXACT []
xref: UBERON:0002103
is_a: XAO:0003027 ! limb
relationship: develops_from XAO:0003066 ! hindlimb bud
relationship: part_of XAO:0004285 ! pelvic appendage

[Term]
id: XAO:0003032
name: digit
namespace: xenopus_anatomy
def: "One of several most distal parts of a limb." [UBERON:0002544]
xref: UBERON:0002544
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004265 ! autopod
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003033
name: nostril
namespace: xenopus_anatomy
def: "Surface structure that provides one of the small external openings of the head that give passage to air for breathing." [http://dictionary.reference.com/medical/nostril]
xref: UBERON:0005928
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000070 ! NF stage 58

[Term]
id: XAO:0003034
name: viscus
namespace: xenopus_anatomy
def: "An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper." [BTO:0001491]
synonym: "viscera" RELATED PLURAL []
xref: UBERON:0002075
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003035
name: hindlimb digit
namespace: xenopus_anatomy
def: "Any of the 5 digits that are the most distal parts of a hindlimb, each digit consisting of a single metatarsal, 2-4 phalanges, and a claw." [XAO:CJZ]
synonym: "hind digit" EXACT []
synonym: "pedal digit" EXACT []
synonym: "toe" EXACT []
xref: UBERON:0001466
is_a: XAO:0003032 ! digit
relationship: part_of XAO:0003062 ! hindlimb skeleton
relationship: part_of XAO:0004300 ! foot

[Term]
id: XAO:0003036
name: forelimb digit
namespace: xenopus_anatomy
def: "Any of the 4 digits that are the most distal part of a forelimb, each digit consisting of a single metatarsal and 2-3 phalanges. Xenopus forelimb digits are numbered 2-5, with no digit number 1." [XAO:CJZ]
synonym: "fore digit" EXACT []
synonym: "manual digit" EXACT []
xref: UBERON:0002389
is_a: XAO:0003032 ! digit
relationship: part_of XAO:0003061 ! forelimb skeleton
relationship: part_of XAO:0004299 ! hand
relationship: start_stage XAO:1000068 ! NF stage 56

[Term]
id: XAO:0003037
name: multi-tissue structure
namespace: xenopus_anatomy
def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055]
xref: CARO:0000055
xref: UBERON:0000481
is_a: XAO:0005002 ! multicellular anatomical structure
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0003038
name: simple organ
namespace: xenopus_anatomy
def: "Multi-tissue structure that is not part of a compound organ." [CARO:0000021]
xref: CARO:0000021
xref: UBERON:0000472
is_a: XAO:0003037 ! multi-tissue structure
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0003039
name: compound organ component
namespace: xenopus_anatomy
def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019]
xref: CARO:0000019
xref: UBERON:0000471
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0003041 ! compound organ
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0003040
name: tissue
namespace: xenopus_anatomy
def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organization is at least partly a repetition of their short-range organization." [CARO:0000043]
synonym: "portion of tissue" EXACT []
xref: CARO:0000043
xref: UBERON:0000479
is_a: XAO:0005002 ! multicellular anatomical structure
relationship: start_stage XAO:1000017 ! NF stage 7

[Term]
id: XAO:0003041
name: compound organ
namespace: xenopus_anatomy
def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024]
xref: CARO:0000024
xref: UBERON:0003103
is_a: XAO:0005002 ! multicellular anatomical structure
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0003042
name: embryonic structure
namespace: xenopus_anatomy
def: "An anatomical structure that exists only before the organism is fully formed." [BTO:0000174]
xref: UBERON:0002050
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003000 ! anatomical structure
relationship: develops_from XAO:0000113 ! embryo
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000113 ! embryo
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0003043
name: primordium
namespace: xenopus_anatomy
def: "An embryonic structure that is the rudiment or commencement of a part or organ." [UBERON:0001048]
synonym: "primordia" RELATED PLURAL []
xref: UBERON:0001048
is_a: XAO:0003042 ! embryonic structure
relationship: start_stage XAO:1000017 ! NF stage 7

[Term]
id: XAO:0003044
name: endomesoderm
namespace: xenopus_anatomy
def: "Primary germ layer that can give rise to both mesoderm and endoderm." [XAO:curators]
synonym: "mesendoderm" RELATED []
xref: UBERON:0000089
is_a: XAO:0003011 ! primary germ layer

[Term]
id: XAO:0003045
name: epithelium
namespace: xenopus_anatomy
def: "Portion of tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and that is underlain by a basal lamina." [CARO:0000066]
xref: CARO:0000066
xref: UBERON:0000483
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0003046
name: mesenchyme
namespace: xenopus_anatomy
def: "Portion of embryonic tissue consisting of loosely organized, undifferentiated mesodermal or neural crest derived cells, that have specific properties (they are migratory, have no polarity). Mesenchyme cells are incorporated into a wide variety of structures including connective tissue, blood, bone and cartilage as development continues." [AAO:0010427, XAO:CJZ]
synonym: "mesenchymal tissue" RELATED []
xref: UBERON:0003104
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0003047
name: nerve
namespace: xenopus_anatomy
def: "Portion of tissue that consists of a fasciculated group of axons." [XAO:curators]
xref: UBERON:0001021
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000177 ! nervous system
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003048
name: egg
namespace: xenopus_anatomy
def: "A mature female germ cell that is capable of initiating formation of a new individual by fusion with a male gamete." [http://www.merriam-webster.com/medlineplus/gamete]
synonym: "ovum" RELATED []
synonym: "unfertilized egg" RELATED []
xref: CL:0000025
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003150 ! gamete
relationship: develops_from XAO:0000256 ! oocyte

[Term]
id: XAO:0003049
name: adipose tissue
namespace: xenopus_anatomy
def: "Connective tissue in which fat is stored." [http://www.merriam-webster.com/medlineplus/adipose+tissue]
xref: UBERON:0001013
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003050
name: fat body
namespace: xenopus_anatomy
def: "Anatomical structure associated with the gonads that vary in form among amphibians but are primarily composed of adipose tissue and are thought to be a source of nutrients for the gonads. A body of adipose tissue, in the form of finger-like projections, usually associated with the anterior end of the testis and ovaries. Fat bodies are suspended from the body wall by dorsal mesentry which is fused with the gonadal mesentry (the mesovarium or mesorchidium)." [AAO:0000157, ISBN:0070179778]
xref: UBERON:0003428
is_a: XAO:0003049 ! adipose tissue
relationship: start_stage XAO:1000064 ! NF stage 52

[Term]
id: XAO:0003051
name: anterior dorsal lateral plate region
namespace: xenopus_anatomy
def: "Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo." [PMID:9618755]
synonym: "ADLPR" EXACT []
synonym: "AGM region" RELATED []
synonym: "aorta-gonads-mesonephros region" RELATED []
synonym: "dorsal lateral plate region" BROAD []
xref: UBERON:0003105
is_a: XAO:0003042 ! embryonic structure
relationship: part_of XAO:0000122 ! hematological system
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0003052
name: oviduct
namespace: xenopus_anatomy
def: "A simple ciliated tube through which the ovum travels from the ovaries to the cloaca and the external environment. It is lined with mucus-secreting glands that produce the jelly that surrounds the ovum." [http://en.wikipedia.org/wiki/Oviduct]
xref: UBERON:0000993
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000330 ! Mullerian duct
relationship: part_of XAO:0000156 ! female genitalia
relationship: start_stage XAO:1000076 ! NF stage 64

[Term]
id: XAO:0003053
name: Keller explant
namespace: xenopus_anatomy_in_vitro
def: "A rectangle of dorsal mesendoderm and ectoderm from an early-gastrula-stage Xenopus laevis embryo. It is approximately 60 deg to 90 deg wide, extending from the bottle cells to the animal pole." [ISBN:9780879695040]
is_a: XAO:0003007 ! anatomical entity in vitro

[Term]
id: XAO:0003054
name: stem cell
namespace: xenopus_anatomy
def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034]
xref: CL:0000034
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0003055
name: hematopoietic stem cell
namespace: xenopus_anatomy
def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, ZFA:0009014]
synonym: "HSC" EXACT []
xref: CL:0000037
is_a: XAO:0003054 ! stem cell
relationship: part_of XAO:0000067 ! ventral blood island
relationship: part_of XAO:0003051 ! anterior dorsal lateral plate region
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0003056
name: anterior
namespace: xenopus_anatomy
def: "Spatial concept denoting the front surface of the body; often used to indicate the position of one structure relative to another." [NCIt:Anterior]
subset: anatomical_site_slim
subset: sectional_anatomy_items
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0003057
name: posterior
namespace: xenopus_anatomy
def: "Spatial concept denoting the back surface of the body." [NCIt:Posterior]
subset: anatomical_site_slim
subset: sectional_anatomy_items
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0003059
name: chondrocranium
namespace: xenopus_anatomy
def: "Anatomical cluster consisting of a cartilaginous skull that begins to form during early tadpole stage." [ISBN:0471209627]
synonym: "cartilaginous skull" RELATED []
xref: UBERON:0004761
is_a: XAO:0003075 ! cranium

[Term]
id: XAO:0003060
name: skeletal system
namespace: xenopus_anatomy
def: "Anatomical system that provides physical support to the organism." [AAO:0000566]
xref: UBERON:0001434
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0000168 ! musculoskeletal system
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003061
name: forelimb skeleton
namespace: xenopus_anatomy
def: "Skeletal structure of the paired, anterior appendages." [AAO:0000202]
xref: UBERON:0001440
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0003166 ! appendicular skeleton
relationship: start_stage XAO:1000068 ! NF stage 56

[Term]
id: XAO:0003062
name: hindlimb skeleton
namespace: xenopus_anatomy
def: "Skeletal structure of the paired, posterior appendages." [AAO:0000217]
synonym: "hind limb skeleton" EXACT []
xref: UBERON:0001441
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0003166 ! appendicular skeleton
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003063
name: pectoral girdle
namespace: xenopus_anatomy
def: "Arched skeletal structure that supports the forelimbs, the rudiments of which can be distinguished in mesenchyme at NF stage 51, and is complete by NF stage 60." [http://www.merriam-webster.com/medlineplus/pectoral+girdle, ISBN:0471209627]
synonym: "shoulder girdle" RELATED []
xref: UBERON:0007831
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0003166 ! appendicular skeleton
relationship: start_stage XAO:1000063 ! NF stage 51

[Term]
id: XAO:0003064
name: pelvic girdle
namespace: xenopus_anatomy
def: "Arched skeletal structure that supports the hindlimbs, begins to develop at NF stage 50, and is ossified by NF stage 66." [http://www.merriam-webster.com/medlineplus/pelvic+girdle, ISBN:0471209627]
synonym: "pelic skeleton" RELATED []
synonym: "pelvis" RELATED []
synonym: "pelvis skeleton" RELATED []
xref: UBERON:0007832
is_a: XAO:0004289 ! skeletal subdivision
relationship: develops_from XAO:0004493 ! pelvic girdle primordium
relationship: part_of XAO:0003166 ! appendicular skeleton
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003065
name: forelimb bud
namespace: xenopus_anatomy
def: "The anterior limb bud that develops into the fore limb; oval shaped in dorsal aspect by NF stage 50, and paddle shaped by NF stage 53; all four fingers and melanophores apparent by NF stage 54." [XAO:curators]
xref: UBERON:0005417
is_a: XAO:0003161 ! limb bud
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0003066
name: hindlimb bud
namespace: xenopus_anatomy
def: "The posterior limb bud that develops into the hindlimb; a thickening of the ectoderm first noticeable at NF stage 47, innervated by NF stage 51. The hindlimb buds develop before the forelimb buds." [XAO:curators]
synonym: "hind limb bud" EXACT []
xref: UBERON:0005418
is_a: XAO:0003161 ! limb bud

[Term]
id: XAO:0003073
name: postcranial axial skeleton
namespace: xenopus_anatomy
def: "Skeletal structure that has as its parts the vertebral column, located in the dorsal part of the trunk, and is formed by a series of vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord." [AAO:0000034]
xref: UBERON:0002090
is_a: XAO:0004289 ! skeletal subdivision
relationship: develops_from XAO:0000401 ! sclerotomal cartilage
relationship: part_of XAO:0004011 ! axial skeleton
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003074
name: vertebral column
namespace: xenopus_anatomy
def: "Anatomical cluster that consists of all the vertebrae in the body." [VSAO:0000185]
synonym: "spine" RELATED []
xref: UBERON:0001130
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0003073 ! postcranial axial skeleton
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003075
name: cranium
namespace: xenopus_anatomy
def: "Skeletal system that is part of the head, including the splanchnocranium, chondrocranium, and dermatocranium." [XAO:curators]
synonym: "cranial skeleton" RELATED []
xref: UBERON:0010323
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003024 ! head
relationship: part_of XAO:0003060 ! skeletal system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0003076
name: cervical vertebra
namespace: xenopus_anatomy
def: "The first vertebra, which arises from the trunk somites 1 and 2." [XAO:CJZ]
synonym: "atlas vertebra" EXACT []
synonym: "first vertebra" EXACT []
synonym: "first vertebrae" RELATED PLURAL []
xref: UBERON:0002413
is_a: XAO:0004019 ! vertebra
relationship: develops_from XAO:0000406 ! trunk somite 1
relationship: develops_from XAO:0000407 ! trunk somite 2

[Term]
id: XAO:0003077
name: presacral vertebra
namespace: xenopus_anatomy
def: "The vertebra anterior to the sacral vetebra." [XAO:CJZ]
synonym: "presacral vertebrae" RELATED PLURAL []
xref: UBERON:0004451
is_a: XAO:0004019 ! vertebra
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0003078
name: sacral vertebra
namespace: xenopus_anatomy
def: "The 9th vertebra, which arises from the trunk somites 9 and 10. It joins the illia laterally at NF stage 60 and later coalesces with the urostyle in the midline of the pelvic girdle to form a single unit in the adult frog." [PMID:15679868, XAO:CJZ]
synonym: "ninth vertebra" EXACT []
synonym: "ninth vertebrae" RELATED PLURAL []
synonym: "sacral vertebrae" RELATED PLURAL []
xref: UBERON:0001094
is_a: XAO:0004019 ! vertebra
relationship: develops_from XAO:0000417 ! trunk somite 9
relationship: develops_from XAO:0000418 ! trunk somite 10
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0003079
name: caudal vertebra
namespace: xenopus_anatomy
def: "The bones that make up the tail region of the tadpole." [XAO:curators]
synonym: "caudal vertebrae" RELATED PLURAL []
synonym: "postsacral vertebra" RELATED []
xref: UBERON:0001095
is_a: XAO:0004019 ! vertebra
relationship: part_of XAO:0003064 ! pelvic girdle

[Term]
id: XAO:0003080
name: urostyle
namespace: xenopus_anatomy
def: "Skeletal element in the midline of the pelvic girdle that arises from somites 10-13. It is a rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. It is formed by the fusion of the neural arches of the 10th-13th vertebrae, and the posterior-most remnants of the hypochord. Timing of complete ossification varies between NF stages 62 and 66." [AAO:0000732, PMID:15679868, XAO:CJZ]
xref: UBERON:0003106
is_a: XAO:0004276 ! bone element
relationship: develops_from XAO:0000056 ! hypochord
relationship: develops_from XAO:0000418 ! trunk somite 10
relationship: develops_from XAO:0000419 ! trunk somite 11
relationship: develops_from XAO:0000420 ! trunk somite 12
relationship: develops_from XAO:0000421 ! trunk somite 13
relationship: part_of XAO:0003073 ! postcranial axial skeleton
relationship: start_stage XAO:1000060 ! NF stage 48

[Term]
id: XAO:0003081
name: larynx
namespace: xenopus_anatomy
def: "Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located." [AAO:0000268]
xref: UBERON:0001737
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0000117 ! respiratory system
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0003083
name: braincase and otic capsule skeleton
namespace: xenopus_anatomy
def: "Skeleton encasing the brain and auditory apparatus." [ISBN:0070179778]
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0003084
name: lower jaw
namespace: xenopus_anatomy
def: "Anatomical cluster consisting of the ventral portion of the first pharyngeal arch." [TAO:0001273, XAO:EJS]
synonym: "ventral mandibular arch" RELATED []
xref: UBERON:0003278
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003085
name: Meckel's cartilage
namespace: xenopus_anatomy
def: "Paired cartilaginous component of the lower jaw that fuses together through a median inferior labial cartilage, resulting in a single curved bar of cartilage by metamorphic climax. During metamorphosis it is surrounded by the developing dentale and goniale." [PMID:3693112]
synonym: "cm" EXACT []
xref: UBERON:0003107
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0000024 ! mandibular crest
relationship: part_of XAO:0000097 ! mandibular arch
relationship: part_of XAO:0003084 ! lower jaw
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0003086
name: suspensorium
namespace: xenopus_anatomy
def: "Anatomical cluster consisting of the mandibular structures which connect the base of the lower jaw with the skull." [http://medical-dictionary.thefreedictionary.com/Suspensorium]
xref: UBERON:0003108
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003176 ! splanchnocranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003087
name: upper jaw
namespace: xenopus_anatomy
def: "The dorsal portion of the first pharyngeal arch." [TAO:0001272, XAO:EJS]
synonym: "palatoquadrate arch" RELATED []
xref: UBERON:0003277
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003088
name: seminiferous tubule
namespace: xenopus_anatomy
def: "Any of the coiled tubules located in the testes in which spermatozoa are produced." [AAO:0010399]
xref: UBERON:0001343
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000157 ! testis
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003090
name: oculomotor nerve
namespace: xenopus_anatomy
def: "Cranial nerve that largely consists of somatic efferent fibers which innervate four eye muscles (m rectus superior, m obliquus inferior, and mm rectus inferior and anterior)." [ISBN:080184780X]
synonym: "cranial nerve III" EXACT []
synonym: "oculomotorius" EXACT []
xref: UBERON:0001643
is_a: XAO:0000429 ! cranial nerve
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0003091
name: trochlear nerve
namespace: xenopus_anatomy
def: "Somatic efferent nerve that runs to the superior oblique muscle of the eye." [ISBN:080184780X]
synonym: "cranial nerve IV" EXACT []
synonym: "pathetic nerve" EXACT []
synonym: "trochlearis" EXACT []
xref: UBERON:0001644
is_a: XAO:0000429 ! cranial nerve
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0003092
name: trigeminal nerve
namespace: xenopus_anatomy
def: "Cranial nerve that has three branches: the ophthalmic branch that supplies the skin of the nose and upper jaw, and the maxillary and mandibular branches that supply the lower jaw." [UBERON:0001645]
synonym: "cranial nerve V" EXACT []
synonym: "trigeminus" EXACT []
xref: UBERON:0001645
is_a: XAO:0000429 ! cranial nerve
relationship: develops_from XAO:0004092 ! preplacodal ectoderm

[Term]
id: XAO:0003093
name: abducens nerve
namespace: xenopus_anatomy
def: "Cranial nerve that runs to the eye muscles." [UBERON:0001646]
synonym: "abducens" EXACT []
synonym: "abducent nerve" EXACT []
synonym: "cranial nerve VI" EXACT []
xref: UBERON:0001646
is_a: XAO:0000429 ! cranial nerve
relationship: start_stage XAO:1000061 ! NF stage 49

[Term]
id: XAO:0003094
name: facial nerve
namespace: xenopus_anatomy
def: "Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches)." [ISBN:0471209627]
synonym: "cranial nerve VII" EXACT []
synonym: "facialis" EXACT []
xref: UBERON:0001647
is_a: XAO:0000429 ! cranial nerve
relationship: part_of XAO:0003197 ! gustatory system
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0003095
name: vestibulocochlear nerve
namespace: xenopus_anatomy
def: "Cranial nerve that runs to the ear. It has two branches, the cochlear nerve and the vestibular nerve, which receives positional information." [XAO:curators]
synonym: "auditory nerve" RELATED []
synonym: "cranial nerve VIII" EXACT []
synonym: "stato-acoustic nerve" EXACT []
xref: UBERON:0001648
is_a: XAO:0000429 ! cranial nerve
relationship: part_of XAO:0003195 ! vestibuloauditory system
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0003096
name: glossopharyngeal nerve
namespace: xenopus_anatomy
def: "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." [ISBN:0471209627]
synonym: "cranial nerve IX" EXACT []
xref: UBERON:0001649
is_a: XAO:0000429 ! cranial nerve
relationship: part_of XAO:0003197 ! gustatory system

[Term]
id: XAO:0003097
name: vagus nerve
namespace: xenopus_anatomy
def: "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." [ISBN:0471209627]
synonym: "cranial nerve X" EXACT []
synonym: "vagal nerve" RELATED []
synonym: "vagus afferents" RELATED []
xref: UBERON:0001759
is_a: XAO:0000429 ! cranial nerve
relationship: develops_from XAO:0000284 ! epibranchial placode
relationship: part_of XAO:0003197 ! gustatory system
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0003098
name: cerebellum
namespace: xenopus_anatomy
def: "A dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum." [UBERON:0002037]
xref: UBERON:0002037
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000015 ! hindbrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003099
name: fourth ventricle
namespace: xenopus_anatomy
def: "Irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space." [UBERON:0002422]
synonym: "4th ventricle" EXACT []
synonym: "IVth ventricle" EXACT []
xref: UBERON:0002422
is_a: XAO:0004602 ! brain ventricle
relationship: part_of XAO:0000015 ! hindbrain

[Term]
id: XAO:0003100
name: medulla oblongata
namespace: xenopus_anatomy
def: "Posterior portion of the hindbrain that controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses." [AAO:0010486]
xref: UBERON:0001896
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000015 ! hindbrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003101
name: spinal nerve
namespace: xenopus_anatomy
def: "A mixed nerve that carries motor, sensory, and autonomic signals between the spinal cord and the body." [http://en.wikipedia.org/wiki/Spinal_nerve]
xref: UBERON:0001780
is_a: XAO:0003047 ! nerve
relationship: part_of XAO:0000178 ! peripheral nervous system

[Term]
id: XAO:0003102
name: transverse process
namespace: xenopus_anatomy
def: "Any of the projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae." [AAO:0000698]
xref: UBERON:0001077
is_a: XAO:0004020 ! process
relationship: part_of XAO:0004019 ! vertebra
relationship: start_stage XAO:1000073 ! NF stage 61

[Term]
id: XAO:0003103
name: claw
namespace: xenopus_anatomy
def: "Anatomical structure consisting of a small, pointed keratinized appendage at the end of each of the three inner toes of the hindlimbs." [XAO:curators]
xref: UBERON:0001705
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003162 ! acellular anatomical structure
relationship: develops_from XAO:0004416 ! claw primordium
relationship: part_of XAO:0003035 ! hindlimb digit
relationship: start_stage XAO:1000070 ! NF stage 58

[Term]
id: XAO:0003104
name: myotome of head somite 1
namespace: xenopus_anatomy
def: "Compartment of head somite 1 that is a precursor of muscle." [XAO:EJS]
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000396 ! head somite 1
relationship: end_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003105
name: myotome of head somite 2
namespace: xenopus_anatomy
def: "Compartment of head somite 2 that is a precursor of muscle." [XAO:EJS]
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000403 ! head somite 2
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0003106
name: myotome of head somite 3
namespace: xenopus_anatomy
def: "Compartment of head somite 3 that is a precursor of muscle." [XAO:EJS]
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000404 ! head somite 3
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0003107
name: myotome of head somite 4
namespace: xenopus_anatomy
def: "Compartment of head somite 4 that is a precursor of muscle." [XAO:EJS]
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000405 ! head somite 4
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0003108
name: myotome of trunk somite 1
namespace: xenopus_anatomy
def: "Compartment of trunk somite 1 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 1" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000406 ! trunk somite 1
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003109
name: myotome of trunk somite 2
namespace: xenopus_anatomy
def: "Compartment of trunk somite 2 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 2" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000407 ! trunk somite 2
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003110
name: myotome of trunk somite 3
namespace: xenopus_anatomy
def: "Compartment of trunk somite 3 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 3" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000408 ! trunk somite 3
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0003111
name: myotome of trunk somite 4
namespace: xenopus_anatomy
def: "Compartment of trunk somite 4 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 4" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000409 ! trunk somite 4
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0003112
name: sclerotome of head somite 4
namespace: xenopus_anatomy
def: "Compartment of head somite 4 that is a precursor of the axial skeleton." [XAO:EJS]
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000405 ! head somite 4
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0003113
name: sclerotome of trunk somite 1
namespace: xenopus_anatomy
def: "Compartment of trunk somite 1 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 1" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000406 ! trunk somite 1
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003114
name: sclerotome of trunk somite 2
namespace: xenopus_anatomy
def: "Compartment of trunk somite 2 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 2" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000407 ! trunk somite 2
relationship: start_stage XAO:1000035 ! NF stage 19

[Term]
id: XAO:0003115
name: sclerotome of trunk somite 3
namespace: xenopus_anatomy
def: "Compartment of trunk somite 3 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 3" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000408 ! trunk somite 3
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0003116
name: sclerotome of trunk somite 4
namespace: xenopus_anatomy
def: "Compartment of trunk somite 4 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 4" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000409 ! trunk somite 4
relationship: start_stage XAO:1000037 ! NF stage 21

[Term]
id: XAO:0003117
name: myotome of trunk somite 5
namespace: xenopus_anatomy
def: "Compartment of trunk somite 5 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 5" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000410 ! trunk somite 5
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003118
name: myotome of trunk somite 6
namespace: xenopus_anatomy
def: "Compartment of trunk somite 6 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 6" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000411 ! trunk somite 6
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003119
name: myotome of trunk somite 7
namespace: xenopus_anatomy
def: "Compartment of trunk somite 7 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 7" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000412 ! trunk somite 7
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003120
name: myotome of trunk somite 8
namespace: xenopus_anatomy
def: "Compartment of trunk somite 8 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 8" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000416 ! trunk somite 8
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003121
name: sclerotome of trunk somite 5
namespace: xenopus_anatomy
def: "Compartment of trunk somite 5 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 5" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000410 ! trunk somite 5
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003122
name: sclerotome of trunk somite 6
namespace: xenopus_anatomy
def: "Compartment of trunk somite 6 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 6" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000411 ! trunk somite 6
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0003123
name: sclerotome of trunk somite 7
namespace: xenopus_anatomy
def: "Compartment of trunk somite 7 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 7" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000412 ! trunk somite 7
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003124
name: sclerotome of trunk somite 8
namespace: xenopus_anatomy
def: "Compartment of trunk somite 8 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 8" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000416 ! trunk somite 8
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003125
name: myotome of trunk somite 9
namespace: xenopus_anatomy
def: "Compartment of trunk somite 9 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 9" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000417 ! trunk somite 9
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003126
name: sclerotome of trunk somite 9
namespace: xenopus_anatomy
def: "Compartment of trunk somite 9 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 9" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000417 ! trunk somite 9
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003127
name: sclerotome of trunk somite 10
namespace: xenopus_anatomy
def: "Compartment of trunk somite 10 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 10" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000418 ! trunk somite 10
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003128
name: myotome of trunk somite 10
namespace: xenopus_anatomy
def: "Compartment of trunk somite 10 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 10" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000418 ! trunk somite 10
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003129
name: sclerotome of trunk somite 11
namespace: xenopus_anatomy
def: "Compartment of trunk somite 11 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 11" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000419 ! trunk somite 11
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003130
name: myotome of trunk somite 11
namespace: xenopus_anatomy
def: "Compartment of trunk somite 11 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 11" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000419 ! trunk somite 11
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003131
name: sclerotome of trunk somite 12
namespace: xenopus_anatomy
def: "Compartment of trunk somite 12 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 12" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000420 ! trunk somite 12
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0003132
name: myotome of trunk somite 12
namespace: xenopus_anatomy
def: "Compartment of trunk somite 12 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 12" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000420 ! trunk somite 12
relationship: start_stage XAO:1000041 ! NF stage 25

[Term]
id: XAO:0003133
name: sclerotome of trunk somite 13
namespace: xenopus_anatomy
def: "Compartment of trunk somite 13 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 13" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000421 ! trunk somite 13
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003134
name: myotome of trunk somite 13
namespace: xenopus_anatomy
def: "Compartment of trunk somite 13 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 13" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000421 ! trunk somite 13
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003135
name: sclerotome of tail somite 14
namespace: xenopus_anatomy
def: "Compartment of tail somite 14 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 14" EXACT []
synonym: "sclerotome of trunk somite 14" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000422 ! tail somite 14
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003136
name: myotome of tail somite 14
namespace: xenopus_anatomy
def: "Compartment of tail somite 14 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 14" EXACT []
synonym: "myotome of trunk somite 14" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000422 ! tail somite 14
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003137
name: sclerotome of tail somite 15
namespace: xenopus_anatomy
def: "Compartment of tail somite 15 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 15" EXACT []
synonym: "sclerotome of trunk somite 15" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000423 ! tail somite 15
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0003138
name: myotome of tail somite 15
namespace: xenopus_anatomy
def: "Compartment of tail somite 15 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 15" EXACT []
synonym: "myotome of trunk somite 15" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000423 ! tail somite 15
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0003139
name: sclerotome of tail somite 16
namespace: xenopus_anatomy
def: "Compartment of tail somite 16 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 16" EXACT []
synonym: "sclerotome of trunk somite 16" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000424 ! tail somite 16
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003140
name: myotome of tail somite 16
namespace: xenopus_anatomy
def: "Compartment of tail somite 16 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 16" EXACT []
synonym: "myotome of trunk somite 16" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000424 ! tail somite 16
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003141
name: sclerotome of tail somite 17
namespace: xenopus_anatomy
def: "Compartment of tail somite 17 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 17" EXACT []
synonym: "sclerotome of trunk somite 17" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0000425 ! tail somite 17
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003142
name: myotome of tail somite 17
namespace: xenopus_anatomy
def: "Compartment of tail somite 17 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of somite 17" EXACT []
synonym: "myotome of trunk somite 17" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0000425 ! tail somite 17
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0003143
name: tail somite
namespace: xenopus_anatomy
def: "Any of the somites that form posterior to the trunk and are resorbed at metamorphosis." [XAO:EJS]
xref: UBERON:0009621
is_a: XAO:0000058 ! somite
relationship: part_of XAO:0003026 ! tail
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003144
name: amphibian papilla
namespace: xenopus_anatomy
def: "The principal auditory organ of the frog, which utilizes both mechanical and electrical (hair cell-based) frequency tuning mechanisms for hearing, located near the junction of the utricle and the saccule bones of the inner ear." [PMID:10377339]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0003145
name: basilar papilla
namespace: xenopus_anatomy
def: "A sensory structure in the lagenar portion of an amphibian's membranous labyrinth between the oval and round windows." [XAO:curators]
synonym: "papilla basilaris" EXACT []
xref: UBERON:0002227
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47

[Term]
id: XAO:0003146
name: gonad
namespace: xenopus_anatomy
def: "Anatomical structure that produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins. Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [AAO:0000213, ZFA:0000413]
xref: UBERON:0000991
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000064 ! NF stage 52

[Term]
id: XAO:0003147
name: spermatozoon
namespace: xenopus_anatomy
def: "A mature male germ cell that develops from a spermatid." [CL:0000019]
synonym: "sperm" RELATED []
synonym: "spermatozoa" RELATED PLURAL []
xref: CL:0000019
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003150 ! gamete
relationship: develops_from XAO:0003151 ! spermatid

[Term]
id: XAO:0003148
name: germ line cell
namespace: xenopus_anatomy
is_obsolete: true
replaced_by: XAO:0000111

[Term]
id: XAO:0003149
name: primordial germ cell
namespace: xenopus_anatomy
def: "Cell that arises from the endodermal germ plasm and can be detected by NF stage 28 in the endodermal mass. At NF stages 42-47, PGCs migrate to the two genital ridges, which are the first rudiments of the gonads. By NF stage 50, the PGCs begin to loose their yolky material. In males, starting at NF stage 52, PGCs migrate from the genital ridge cortical region into the medullary tissue, where they will form primary spermatogonia at sexual maturity. In females, the medullary tissue remains free of PGCs; they instead embed in the cortical region and multiply to form primary oogonia, which will mature into ova at sexual maturity." [ISBN:0815318960, XAO:curators]
synonym: "PGC" EXACT []
synonym: "primitive germ cell" RELATED []
xref: CL:0000670
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0000090 ! endoderm
relationship: develops_from XAO:0000233 ! germ plasm
relationship: end_stage XAO:1000070 ! NF stage 58

[Term]
id: XAO:0003150
name: gamete
namespace: xenopus_anatomy
def: "A mature male or female germ cell." [http://www.merriam-webster.com/medlineplus/gamete]
xref: CL:0000300
is_a: XAO:0000111 ! germ cell
relationship: start_stage XAO:1000093 ! adult frog stage

[Term]
id: XAO:0003151
name: spermatid
namespace: xenopus_anatomy
def: "Male germ cell that is derived from spermatocytes and develops into spermatozoa." [NCIt:Spermatid]
xref: CL:0000018
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000111 ! germ cell
relationship: develops_from XAO:0003019 ! spermatocyte
relationship: start_stage XAO:1000071 ! NF stage 59

[Term]
id: XAO:0003152
name: immune system
namespace: xenopus_anatomy
def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [http://www.merriam-webster.com/medlineplus/immune+system]
xref: UBERON:0002405
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0003153
name: larval immune system
namespace: xenopus_anatomy
def: "The immune system of a postembryonic, hatched or immature tadpole, prior to metamorphosis." [XAO:curators]
is_a: XAO:0003152 ! immune system
relationship: end_stage XAO:1000078 ! NF stage 66

[Term]
id: XAO:0003154
name: adult immune system
namespace: xenopus_anatomy
def: "The complete system of biological structures and processes within the adult organism that protects against disease by identifying and killing pathogens and tumor cells." [XAO:curators]
is_a: XAO:0003152 ! immune system
relationship: start_stage XAO:1000093 ! adult frog stage

[Term]
id: XAO:0003155
name: lymphocyte
namespace: xenopus_anatomy
def: "A cell of the B cell, T cell, or natural killer cell lineage." [CL:0000542]
xref: CL:0000542
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0003152 ! immune system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0003156
name: natural killer cell
namespace: xenopus_anatomy
def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [CL:0000623]
synonym: "NK cell" EXACT []
xref: CL:0000623
is_a: XAO:0003155 ! lymphocyte

[Term]
id: XAO:0003157
name: T cell
namespace: xenopus_anatomy
def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [AAO:0010311]
xref: CL:0000084
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003155 ! lymphocyte
relationship: develops_from XAO:0003159 ! thymocyte

[Term]
id: XAO:0003158
name: B cell
namespace: xenopus_anatomy
def: "One of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity." [XAO:curators]
xref: CL:0000236
is_a: XAO:0003155 ! lymphocyte

[Term]
id: XAO:0003159
name: thymocyte
namespace: xenopus_anatomy
def: "An immature T cell located in the thymus." [AAO:0010312]
is_a: XAO:0003155 ! lymphocyte
relationship: part_of XAO:0000163 ! thymus

[Term]
id: XAO:0003160
name: anatomical cluster
namespace: xenopus_anatomy
def: "Anatomical group that has its parts adjacent to one another." [CARO:0000041]
xref: CARO:0000041
xref: UBERON:0000477
is_a: XAO:0003001 ! anatomical group

[Term]
id: XAO:0003161
name: limb bud
namespace: xenopus_anatomy
def: "Structure that is an early outgrowth of a presumptive limb." [AAO:0010375]
xref: UBERON:0004347
is_a: XAO:0003028 ! surface structure
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0003162
name: acellular anatomical structure
namespace: xenopus_anatomy
def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [CARO:0000040]
synonym: "acellular structure" EXACT []
xref: CARO:0000040
xref: UBERON:0000476
is_a: XAO:0003000 ! anatomical structure
relationship: part_of XAO:0003004 ! whole organism

[Term]
id: XAO:0003163
name: basal lamina
namespace: xenopus_anatomy
def: "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." [CARO:0000065]
xref: CARO:0000065
xref: UBERON:0000482
is_a: XAO:0003162 ! acellular anatomical structure
relationship: start_stage XAO:1000020 ! NF stage 10

[Term]
id: XAO:0003164
name: solid compound organ
namespace: xenopus_anatomy
def: "Compound organ that does not contain macroscopic anatomical spaces." [CARO:0000074]
xref: CARO:0000074
xref: UBERON:0000491
is_a: XAO:0003041 ! compound organ

[Term]
id: XAO:0003165
name: cavitated compound organ
namespace: xenopus_anatomy
def: "Compound organ that contains one or more macroscopic anatomical spaces." [CARO:0000072]
xref: CARO:0000072
xref: UBERON:0000489
is_a: XAO:0003041 ! compound organ

[Term]
id: XAO:0003166
name: appendicular skeleton
namespace: xenopus_anatomy
def: "Skeletal structure that has as its parts the pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hindlimbs." [AAO:0000747]
xref: UBERON:0002091
is_a: XAO:0004289 ! skeletal subdivision
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003169
name: dermatocranium
namespace: xenopus_anatomy
def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton." [UBERON:0003113]
xref: UBERON:0003113
is_a: XAO:0003075 ! cranium

[Term]
id: XAO:0003170
name: neurocranium
namespace: xenopus_anatomy
def: "Anatomical cluster that consists of the cartilages and bones that surround the brain." [TAO:0001580, XAO:EJS]
xref: UBERON:0001703
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003171
name: orbital region
namespace: xenopus_anatomy
def: "An anatomical cluster that is part of the cranium and structurally supports the eye." [AAO:0010220]
xref: UBERON:0001697
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003172
name: olfactory region
namespace: xenopus_anatomy
def: "Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs." [AAO:0010206]
xref: UBERON:0003112
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003173
name: occipital region
namespace: xenopus_anatomy
def: "An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles." [AAO:0010199]
xref: UBERON:0005902
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003174
name: sphenoid region
namespace: xenopus_anatomy
def: "Anatomical cluster that forms the floor and side walls of the middle part of the cranium." [UBERON:0003111]
xref: UBERON:0003111
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0003175
name: otic region
namespace: xenopus_anatomy
def: "Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system." [AAO:0010208]
xref: UBERON:0003110
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003075 ! cranium
relationship: start_stage XAO:1000055 ! NF stage 43

[Term]
id: XAO:0003176
name: splanchnocranium
namespace: xenopus_anatomy
def: "Regional skeletal system of the jaws, hyoid and branchial arches." [XAO:EJS, ZFA:0001216]
xref: UBERON:0008895
is_a: XAO:0003075 ! cranium

[Term]
id: XAO:0003177
name: hyoid arch skeleton
namespace: xenopus_anatomy
def: "Skeletal subdivision comprising the skeletal elements of the hyoid arch." [XAO:EJS]
xref: UBERON:0005884
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0000098 ! hyoid arch
relationship: part_of XAO:0003176 ! splanchnocranium

[Term]
id: XAO:0003178
name: dorsal hyoid arch skeleton
namespace: xenopus_anatomy
def: "Skeletal subdivision comprising the dorsal skeletal elements of the hyoid arch." [XAO:EJS]
xref: UBERON:0011152
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003177 ! hyoid arch skeleton
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003179
name: ventral hyoid arch skeleton
namespace: xenopus_anatomy
def: "Skeletal subdivision comprising the ventral skeletal elements of the hyoid arch." [XAO:EJS]
xref: UBERON:0011153
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003177 ! hyoid arch skeleton
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0003180
name: branchial arch skeleton
namespace: xenopus_anatomy
def: "Skeletal and cartilaginous elements of the branchial arches; the last five of the set of seven pharyngeal arches; generally branchial arch no. 1 is the first branchial arch, or the third pharyngeal arch, but some authors do not follow this convention." [PMID:8589427]
synonym: "gill arch skeleton" RELATED []
synonym: "pharyngeal arch skeleton 3-7" RELATED []
synonym: "visceral arch skeleton" RELATED []
xref: UBERON:0005886
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0000099 ! branchial arch
relationship: part_of XAO:0003176 ! splanchnocranium
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0003181
name: branchial arch skeleton 1
namespace: xenopus_anatomy
def: "Skeletal and cartilaginous elements of the first branchial or pharyngeal arch." [XAO:curators]
is_a: XAO:0003180 ! branchial arch skeleton
relationship: part_of XAO:0000447 ! branchial arch 1

[Term]
id: XAO:0003182
name: branchial arch skeleton 2
namespace: xenopus_anatomy
def: "Skeletal and cartilaginous elements of the second branchial or pharyngeal arch." [XAO:curators]
is_a: XAO:0003180 ! branchial arch skeleton
relationship: part_of XAO:0000449 ! branchial arch 2
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0003183
name: branchial arch skeleton 3
namespace: xenopus_anatomy
def: "Skeletal and cartilaginous elements of the third branchial or pharyngeal arch." [XAO:curators]
is_a: XAO:0003180 ! branchial arch skeleton
relationship: part_of XAO:0000451 ! branchial arch 3
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0003184
name: branchial arch skeleton 4
namespace: xenopus_anatomy
def: "Skeletal and cartilaginous elements of the fourth branchial or pharyngeal arch." [XAO:curators]
is_a: XAO:0003180 ! branchial arch skeleton
relationship: part_of XAO:0000453 ! branchial arch 4
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0003185
name: anatomical direction
namespace: xenopus_anatomy
def: "Any spatial descriptor that describes the orientation of the anatomical features of an embryo." [XAO:curators]
is_a: XAO:0000000 ! Xenopus anatomical entity

[Term]
id: XAO:0003186
name: anatomical region
namespace: xenopus_anatomy
def: "A region of the whole organism that contains a recognizable set of structures or anatomical entities." [XAO:curators]
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: develops_from XAO:0000113 ! embryo
relationship: end_stage XAO:0000437 ! death
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0003187
name: medial
namespace: xenopus_anatomy
def: "Spatial concept pertaining to being toward the middle or inside." [NCIt:Medial]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0003188
name: proximal
namespace: xenopus_anatomy
def: "Spatial concept denoting a part of the body that is closer to the center of the body than another part." [NCIt:Proximal]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0003189
name: distal
namespace: xenopus_anatomy
def: "Spatial concept denoting a part of the body that is farther away from the center of the body than another part." [NCIt:Distal]
subset: anatomical_site_slim
is_a: XAO:0003185 ! anatomical direction

[Term]
id: XAO:0003190
name: anatomical space
namespace: xenopus_anatomy
def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [CARO:0000005]
xref: CARO:0000005
xref: UBERON:0000464
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: develops_from XAO:0000113 ! embryo
relationship: end_stage XAO:0000437 ! death
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000017 ! NF stage 7

[Term]
id: XAO:0003191
name: left atrium
namespace: xenopus_anatomy
def: "The chamber of the heart that receives blood from the lungs." [XAO:EJS]
xref: UBERON:0002079
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0005198 ! cardiac atrium
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0003192
name: right atrium
namespace: xenopus_anatomy
def: "The chamber of the heart that receives blood from the sinus venosus." [XAO:EJS]
xref: UBERON:0002078
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0005198 ! cardiac atrium
relationship: start_stage XAO:1000058 ! NF stage 46

[Term]
id: XAO:0003193
name: cardiac ventricle
namespace: xenopus_anatomy
def: "Cardiac chamber that consists of a wall that surrounds the cavity of a ventricle. The amphibian heart has a single ventricle and an outflow tract with an incomplete spiral septum." [UBERON:0002082]
xref: UBERON:0002082
is_a: XAO:0003165 ! cavitated compound organ
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000050 ! NF stage 37 and 38

[Term]
id: XAO:0003194
name: sensory system
namespace: xenopus_anatomy
def: "Part of the nervous system responsible for processing sensory information." [http://en.wikipedia.org/wiki/Sensory_system]
xref: UBERON:0001032
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0000177 ! nervous system
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0003195
name: vestibuloauditory system
namespace: xenopus_anatomy
def: "The sensory system used for balance and hearing." [XAO:curators]
xref: UBERON:0002105
is_a: XAO:0003194 ! sensory system
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0003196
name: olfactory system
namespace: xenopus_anatomy
def: "The sensory system used for olfaction (the sense of smell)." [http://en.wikipedia.org/wiki/Olfactory_system]
xref: UBERON:0005725
is_a: XAO:0003194 ! sensory system
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0003197
name: gustatory system
namespace: xenopus_anatomy
def: "The sensory system used for the sense of taste." [http://en.wikipedia.org/wiki/Gustatory_system]
xref: UBERON:0001033
is_a: XAO:0003194 ! sensory system
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0003198
name: visual system
namespace: xenopus_anatomy
def: "The sensory system used for sight." [XAO:curators]
xref: UBERON:0002104
is_a: XAO:0003194 ! sensory system

[Term]
id: XAO:0003199
name: lymphatic system
namespace: xenopus_anatomy
def: "Part of the circulatory system that consists of a series of vessels that collect blood (exclusive of erythrocytes) which seeps through capillary walls and return it to the veins. The lymphatic system of vasculature drains lymph fluid from the tissue spaces of most organs and returns it to the blood vasculature for recirculation. The lymphatic sytem functions in immune responses. Anurans generate a lot of lymphatic fluid, largely as a consequence of their very leaky vasculature and high interstitial compliance. Lymph is ultimately pumped into the venous system by paired, dorsally located lymph hearts. Hedrick et al (2007) showed that lung inflation and deflation assists lymph movement. Lymph is moved during lung deflation to the subvertebral sac from anterior and posterior lymph sacs. During lung inflation, increased lymph sac pressure moves lymph to axillary regions, where lymph hearts can return lymph to the vascular space." [AAO:0010522, PMID:17981861, XAO:curators]
xref: UBERON:0002465
is_a: XAO:0003002 ! anatomical system
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0003200
name: gut epithelium
namespace: xenopus_anatomy
def: "The epithelium of the gut." [XAO:curators]
xref: UBERON:0003929
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0003201
name: oral epithelium
namespace: xenopus_anatomy
def: "Epithelium that lines the oral cavity, with many short microvilli as well as mucous cells, rodlet cells and taste buds." [UBERON:0002424]
xref: UBERON:0002424
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0003029 ! mouth
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0003202
name: pharyngeal epithelium
namespace: xenopus_anatomy
def: "Epithelium lining the pharynx, consisting largely of simple columnar epithelium." [TAO:0001174, XAO:EJS]
xref: UBERON:0003351
is_a: XAO:0004007 ! unilaminar epithelium
relationship: start_stage XAO:1000043 ! NF stage 27

[Term]
id: XAO:0003203
name: dental epithelium
namespace: xenopus_anatomy
def: "Epithelium that is part of a developing tooth or dental organ." [XAO:EJS, ZFA:0005134]
xref: UBERON:0003843
is_a: XAO:0003045 ! epithelium
relationship: start_stage XAO:1000072 ! NF stage 60

[Term]
id: XAO:0003204
name: neural tube
namespace: xenopus_anatomy
def: "Hollow epithelial tube on the dorsal side of the embryo that develops into the brain and spinal cord." [AAO:0010617]
xref: UBERON:0001049
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000248 ! neural groove
relationship: develops_from XAO:0000249 ! neural plate
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000215 ! central nervous system
relationship: start_stage XAO:1000027 ! NF stage 17

[Term]
id: XAO:0003205
name: chondrocyte
namespace: xenopus_anatomy
def: "Polymorphic cell type that forms cartilage." [CL:0000138]
synonym: "cartilage cell" RELATED []
xref: CL:0000138
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0003238 ! chondroblast
relationship: part_of XAO:0000170 ! cartilage tissue
relationship: start_stage XAO:1000048 ! NF stage 33 and 34

[Term]
id: XAO:0003206
name: podocyte
namespace: xenopus_anatomy
def: "Cell type that is a component of the glomus." [XAO:curators]
synonym: "podocytes" RELATED PLURAL []
xref: CL:0000653
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0000318 ! glomus
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0003207
name: carpus
namespace: xenopus_anatomy
def: "The cluster of bones in the wrist between the radius, ulna and metacarpus, they do not belong to individual fingers, but allow the wrist to move and rotate." [ISBN:0070179778]
xref: UBERON:0009880
is_a: XAO:0004276 ! bone element
relationship: part_of XAO:0003061 ! forelimb skeleton
relationship: part_of XAO:0004299 ! hand
relationship: start_stage XAO:1000069 ! NF stage 57

[Term]
id: XAO:0003208
name: metacarpus
namespace: xenopus_anatomy
def: "Each of the bones forming the part of the hand between the fingers and the wrist." [http://www.infovisual.info/02/028_en.html]
xref: UBERON:0010544
is_a: XAO:0004276 ! bone element
relationship: part_of XAO:0003061 ! forelimb skeleton
relationship: part_of XAO:0004299 ! hand
relationship: start_stage XAO:1000069 ! NF stage 57

[Term]
id: XAO:0003209
name: radio-ulna
namespace: xenopus_anatomy
def: "Either of the paired, long bones of endochondral origin formed by the fusion of the radius and ulna." [AAO:0000901]
synonym: "radioulna" EXACT []
synonym: "radius-ulna" EXACT []
xref: UBERON:0006715
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003061 ! forelimb skeleton
relationship: part_of XAO:0004297 ! forelimb zeugopod
relationship: start_stage XAO:1000068 ! NF stage 56

[Term]
id: XAO:0003210
name: humerus
namespace: xenopus_anatomy
def: "Either of the paired, elongate, cylindrical forelimb bones of endochondral origin that extend from the pectoral girdle (shoulders) to the elbows." [AAO:0000679, XAO:curators]
xref: UBERON:0000976
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003061 ! forelimb skeleton
relationship: part_of XAO:0004295 ! forelimb stylopod
relationship: start_stage XAO:1000068 ! NF stage 56

[Term]
id: XAO:0003211
name: tarsus
namespace: xenopus_anatomy
def: "A bone of the wrist of the hindlimb, which remains cartilaginous until NF stage 66." [ISBN:0815318960]
synonym: "tarsalia" EXACT []
xref: UBERON:0009879
is_a: XAO:0004276 ! bone element
relationship: part_of XAO:0003062 ! hindlimb skeleton
relationship: part_of XAO:0004300 ! foot
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003212
name: metatarsus
namespace: xenopus_anatomy
def: "Each of the bones forming the part of the foot between the toes and the heel." [http://www.infovisual.info/02/028_en.html]
xref: UBERON:0010545
is_a: XAO:0004276 ! bone element
relationship: part_of XAO:0003062 ! hindlimb skeleton
relationship: part_of XAO:0004300 ! foot
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003213
name: tibia-fibula
namespace: xenopus_anatomy
def: "Bone of the lower hind leg, which undergoes ossification from NF stage 56 to stage 66." [ISBN:0471209627]
synonym: "tibiofibula" EXACT []
xref: UBERON:0006714
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003062 ! hindlimb skeleton
relationship: part_of XAO:0004298 ! hindlimb zeugopod
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003214
name: femur
namespace: xenopus_anatomy
def: "Either of the paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees. Proximal bone of the hind leg, which begins to ossify at NF stage 55." [ISBN:0471209627]
xref: UBERON:0000981
is_a: XAO:0004018 ! endochondral bone
relationship: develops_from XAO:0004238 ! femur rudiment
relationship: part_of XAO:0003062 ! hindlimb skeleton
relationship: part_of XAO:0004296 ! hindlimb stylopod
relationship: start_stage XAO:1000067 ! NF stage 55

[Term]
id: XAO:0003215
name: photoreceptor layer
namespace: xenopus_anatomy
def: "The layer within the retina where the photoreceptor cell receptor segments reside." [XAO:EJS, ZFA:0000143]
synonym: "retinal photoreceptor layer" RELATED []
xref: UBERON:0001787
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:17Z

[Term]
id: XAO:0003216
name: retinal neural layer
namespace: xenopus_anatomy
def: "The layer of nerve cells in the retina." [XAO:curators]
synonym: "neural retina" RELATED []
xref: UBERON:0003902
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000009 ! retina
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell
creation_date: 2009-07-15T02:02:33Z

[Term]
id: XAO:0003217
name: retinal pigmented epithelium
namespace: xenopus_anatomy
def: "The monolayer of pigmented epithelium covering the neural retina." [XAO:EJS, ZFA:0000144]
synonym: "pigmented epithelium" RELATED []
synonym: "pigmented retinal epithelium" RELATED []
xref: UBERON:0001782
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0000009 ! retina
relationship: start_stage XAO:1000047 ! NF stage 32
created_by: eriksegerdell
creation_date: 2009-07-15T02:05:18Z

[Term]
id: XAO:0003218
name: retinal outer plexiform layer
namespace: xenopus_anatomy
def: "The layer within the retina where the bipolar cells synapse with the photoreceptor cells." [UBERON:0001790]
xref: UBERON:0001790
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:28Z

[Term]
id: XAO:0003219
name: retinal outer nuclear layer
namespace: xenopus_anatomy
def: "The layer within the retina where the photoreceptor cell bodies reside." [UBERON:0001789]
xref: UBERON:0001789
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:30Z

[Term]
id: XAO:0003220
name: optic fiber layer
namespace: xenopus_anatomy
def: "Fiber layer adjacent the retinal ganglion cell layer that comprises its axons as they traverse to the optic nerve." [XAO:EJS, ZFA:0001619]
xref: UBERON:0001793
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:32Z

[Term]
id: XAO:0003221
name: retinal inner nuclear layer
namespace: xenopus_anatomy
def: "The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells." [UBERON:0001791]
xref: UBERON:0001791
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:34Z

[Term]
id: XAO:0003222
name: inner limiting membrane
namespace: xenopus_anatomy
def: "Retinal layer composed of the basal lamina of Muller cells." [NCIt:Inner_Limiting_Membrane]
xref: UBERON:0001794
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:37Z

[Term]
id: XAO:0003223
name: retinal ganglion cell layer
namespace: xenopus_anatomy
def: "Innermost nuclear layer of the retina, consisting of retinal ganglion cells, containing neurons that project axons through the optic nerve to the brain." [UBERON:0001792]
xref: UBERON:0001792
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:41Z

[Term]
id: XAO:0003224
name: outer limiting membrane
namespace: xenopus_anatomy
def: "A thin fenestrated layer of the pars nervosa retinae adjacent to the outer nuclear layer and through which extend the visual rods and cones." [NCIt:Outer_Limiting_Membrane]
xref: UBERON:0001788
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:44Z

[Term]
id: XAO:0003225
name: retinal inner plexiform layer
namespace: xenopus_anatomy
def: "The plexiform layer of the retina positioned between the inner nuclear layer and the ganglion cell layer and containing the dendrites of retinal ganglion cells and processes of bipolar and amacrine cells." [UBERON:0001795]
xref: UBERON:0001795
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2009-07-15T02:26:47Z

[Term]
id: XAO:0003226
name: optic tectum
namespace: xenopus_anatomy
def: "Structure that is the anterodorsal-most region of the midbrain and is responsible for auditory and visual reflexes." [XAO:curators]
synonym: "midbrain tectum" RELATED []
synonym: "OT" EXACT []
synonym: "tectum" RELATED []
synonym: "tectum opticum" RELATED []
xref: UBERON:0001945
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000014 ! midbrain
relationship: part_of XAO:0000014 ! midbrain
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2009-07-15T03:37:08Z

[Term]
id: XAO:0003227
name: pharynx
namespace: xenopus_anatomy
def: "Anatomical cavity bounded by the derivatives of the branchial arches." [AAO:0000967]
xref: UBERON:0001042
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: eriksegerdell
creation_date: 2009-07-16T02:04:46Z

[Term]
id: XAO:0003228
name: hypaxial muscle
namespace: xenopus_anatomy
def: "Type of trunk muscle that lies ventral to the horizontal septum of the vertebrae and is innervated by the ventral ramus of the spinal nerves. The arise from migratory somitic cells along the lower margin of the trunk somites." [UBERON:0008777, XAO:curator]
synonym: "body wall muscle" RELATED []
xref: UBERON:0008777
is_a: XAO:0000174 ! skeletal muscle
relationship: develops_from XAO:0005226 ! migrating myoblast
relationship: part_of XAO:0003230 ! trunk musculature
created_by: eriksegerdell
creation_date: 2009-07-16T02:14:05Z

[Term]
id: XAO:0003229
name: epaxial muscle
namespace: xenopus_anatomy
def: "Trunk muscle that lies dorsal to the horizontal septum of the vertebrae." [XAO:curators]
synonym: "epaxial muscles" EXACT PLURAL []
xref: UBERON:0008778
is_a: XAO:0000174 ! skeletal muscle
relationship: part_of XAO:0003230 ! trunk musculature
created_by: eriksegerdell
creation_date: 2009-07-16T02:17:32Z

[Term]
id: XAO:0003230
name: trunk musculature
namespace: xenopus_anatomy
def: "Muscle that is located posterior to the head and anterior to the tail and consists of epaxial and hypaxial muscle." [XAO:EJS]
xref: UBERON:0001774
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2009-07-16T02:18:03Z

[Term]
id: XAO:0003231
name: absorptive cell
namespace: xenopus_anatomy
def: "A cell that takes up stuff and metabolizes it." [CL:0000212]
xref: CL:0000212
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:12:02Z

[Term]
id: XAO:0003232
name: acid secreting cell
namespace: xenopus_anatomy
def: "Any of the cell types of the digestive system that secrete amino acid peptides or polypeptides." [CL:0000161]
xref: CL:0000161
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:15:23Z

[Term]
id: XAO:0003233
name: acinar cell
namespace: xenopus_anatomy
def: "Exocrine functioning cells of the pancreas." [CL:0000622]
xref: CL:0000622
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000136 ! pancreas
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2009-07-20T01:16:38Z

[Term]
id: XAO:0003234
name: alkali secreting cell
namespace: xenopus_anatomy
def: "A cell that secretes alkaline substances." [XAO:curators]
xref: CL:0000435
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:17:42Z

[Term]
id: XAO:0003235
name: barrier cell
namespace: xenopus_anatomy
def: "A cell whose primary function is to prevent the transport of stuff across compartments." [CL:0000215]
xref: CL:0000215
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000017 ! NF stage 7
created_by: eriksegerdell
creation_date: 2009-07-20T01:18:52Z

[Term]
id: XAO:0003236
name: barrier epithelial cell
namespace: xenopus_anatomy
def: "A surface epithelial cell of stratified squamous epithelium of cornea, tongue, oral cavity, esophagus or cloaca." [XAO:curators]
xref: CL:0000073
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell
creation_date: 2009-07-20T01:19:57Z

[Term]
id: XAO:0003237
name: cementoblast
namespace: xenopus_anatomy
def: "A cell of ectomesenchymal origin concerned with the formation of the layer of cementum on the roots of teeth." [ISBN:0781733901]
xref: CL:0000061
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000072 ! NF stage 60
created_by: eriksegerdell
creation_date: 2009-07-20T01:23:10Z

[Term]
id: XAO:0003238
name: chondroblast
namespace: xenopus_anatomy
def: "A cell that originates from a mesenchymal stem cell and forms chondrocytes (cartilage cells). Chondroblasts that become embedded in the matrix are called chondrocytes." [XAO:curators]
xref: CL:0000058
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0004320 ! mesenchymal stem cell
relationship: start_stage XAO:1000033 ! NF stage 12.5
created_by: eriksegerdell
creation_date: 2009-07-20T01:24:55Z

[Term]
id: XAO:0003239
name: circulating cell
namespace: xenopus_anatomy
def: "A cell that moves among different tissues of the body, via blood, lymph, or other medium." [CL:0000080]
xref: CL:0000080
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0001010 ! circulatory system
relationship: start_stage XAO:1000027 ! NF stage 17
created_by: eriksegerdell
creation_date: 2009-07-20T01:26:48Z

[Term]
id: XAO:0003240
name: digestive enzyme secreting cell
namespace: xenopus_anatomy
def: "A type of cell, found in the digestive tract, that secrete enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body." [http://en.wikipedia.org/wiki/Digestive_enzyme]
synonym: "digestive enzyme secreting cells" EXACT PLURAL []
xref: CL:0000470
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2009-07-20T01:30:09Z

[Term]
id: XAO:0003241
name: early embryonic cell
namespace: xenopus_anatomy
def: "A cell found in the embryo before the formation of all the germ layers is complete." [CL:0000007]
xref: CL:0000007
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000033 ! NF stage 12.5
relationship: part_of XAO:0000113 ! embryo
relationship: start_stage XAO:1000001 ! NF stage 1
created_by: eriksegerdell
creation_date: 2009-07-20T01:31:42Z

[Term]
id: XAO:0003242
name: morula cell
namespace: xenopus_anatomy
def: "A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass." [CL:0000360]
xref: CL:0000360
is_a: XAO:0003241 ! early embryonic cell
relationship: end_stage XAO:1000019 ! NF stage 9
relationship: start_stage XAO:1000017 ! NF stage 7
created_by: eriksegerdell
creation_date: 2009-07-20T01:32:43Z

[Term]
id: XAO:0003244
name: gastrula cell
namespace: xenopus_anatomy
def: "A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers." [CL:0000361]
xref: CL:0000361
is_a: XAO:0003241 ! early embryonic cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:32:48Z

[Term]
id: XAO:0003245
name: ectodermal cell
namespace: xenopus_anatomy
def: "A cell of the outer of the three germ layers of the embryo." [CL:0000221]
synonym: "ectoderm cell" EXACT []
xref: CL:0000221
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000001 ! ectoderm
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:35:11Z

[Term]
id: XAO:0003246
name: electrically active cell
namespace: xenopus_anatomy
def: "A cell whose function is determined by the generation or the reception of an electric signal." [CL:0000211]
xref: CL:0000211
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:37:18Z

[Term]
id: XAO:0003247
name: endocrine cell
namespace: xenopus_anatomy
def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [CL:0000163]
xref: CL:0000163
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0004208 ! adenohypophyseal placode
relationship: part_of XAO:0000158 ! endocrine system
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: eriksegerdell
creation_date: 2009-07-20T01:38:59Z

[Term]
id: XAO:0003248
name: endodermal cell
namespace: xenopus_anatomy
def: "A cell of the inner of the three germ layers of the embryo." [CL:0000223]
synonym: "endoderm cell" EXACT []
xref: CL:0000223
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:40:37Z

[Term]
id: XAO:0003249
name: epithelial cell
namespace: xenopus_anatomy
def: "A cell that is usually found in a two-dimensional sheet with a free surface." [CL:0000066]
xref: CL:0000066
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0003045 ! epithelium
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T01:42:50Z

[Term]
id: XAO:0003250
name: exocrine cell
namespace: xenopus_anatomy
def: "A cell of an exocrine gland, i.e. a gland that discharges its secretion via a duct." [CL:0000152]
xref: CL:0000152
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2009-07-20T01:44:46Z

[Term]
id: XAO:0003251
name: hatching gland cell
namespace: xenopus_anatomy
def: "Individual secretory cells of the hatching gland that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching." [XAO:curators]
xref: CL:0000249
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: part_of XAO:0000034 ! hatching gland
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: eriksegerdell
creation_date: 2009-07-20T01:48:20Z

[Term]
id: XAO:0003252
name: keratin accumulating cell
namespace: xenopus_anatomy
def: "A cell that is specialized to accumulate keratins, a family of fibrous structural proteins." [http://en.wikipedia.org/wiki/Keratin]
xref: CL:0000311
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2009-07-20T01:52:10Z

[Term]
id: XAO:0003253
name: ligament cell
namespace: xenopus_anatomy
def: "Type of cell that is capable of generating and maintaining the fibrous connective tissue of the ligament." [XAO:EJS]
xref: CL:0000384
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0004031 ! ligament
relationship: start_stage XAO:1000040 ! NF stage 24
created_by: eriksegerdell
creation_date: 2009-07-20T01:52:51Z

[Term]
id: XAO:0003254
name: Merkel cell
namespace: xenopus_anatomy
def: "A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute." [CL:0000242]
xref: CL:0000242
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000039 ! NF stage 23
created_by: eriksegerdell
creation_date: 2009-07-20T01:56:02Z

[Term]
id: XAO:0003255
name: mesodermal cell
namespace: xenopus_anatomy
def: "A cell of the middle germ layer of the embryo." [CL:0000222]
synonym: "mesoderm cell" EXACT []
xref: CL:0000222
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T02:00:17Z

[Term]
id: XAO:0003256
name: mucus secreting cell
namespace: xenopus_anatomy
def: "A type of epithelial cell, found in the epidermis and digestive system, whose function is to secrete mucin, which dissolves in water to form protective mucus." [http://en.wikipedia.org/wiki/Mucus]
xref: CL:0000319
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2009-07-20T02:06:11Z

[Term]
id: XAO:0003257
name: myelin accumulating cell
namespace: xenopus_anatomy
def: "A cell that is specialized to accumulate myelin." [XAO:EJS]
xref: CL:0000328
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2009-07-20T02:06:51Z

[Term]
id: XAO:0003258
name: neuromast mantle cell
namespace: xenopus_anatomy
def: "A non-sensory cell type surrounding the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secreting cupula in which the ciliary bundles of all the hair cells are embedded." [CL:0000851]
xref: CL:0000851
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000023 ! skin
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell
creation_date: 2009-07-20T02:07:36Z

[Term]
id: XAO:0003259
name: neuromast support cell
namespace: xenopus_anatomy
def: "A non-sensory cell of the neuromast that extends between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells." [CL:0000852]
xref: CL:0000852
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000023 ! skin
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell
creation_date: 2009-07-20T02:09:08Z

[Term]
id: XAO:0003260
name: nucleate erythrocyte
namespace: xenopus_anatomy
def: "An erythrocyte having a nucleus." [CL:0000562]
xref: CL:0000562
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2009-07-20T02:10:45Z

[Term]
id: XAO:0003261
name: olfactory epithelial support cell
namespace: xenopus_anatomy
def: "A non-ciliated columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium." [CL:0000853]
xref: CL:0000853
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000039 ! NF stage 23
created_by: eriksegerdell
creation_date: 2009-07-20T02:14:47Z

[Term]
id: XAO:0003262
name: oxygen accumulating cell
namespace: xenopus_anatomy
def: "A cell that is specialized to accumulate oxygen." [XAO:EJS]
xref: CL:0000329
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T02:16:28Z

[Term]
id: XAO:0003263
name: paracrine cell
namespace: xenopus_anatomy
def: "A secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it." [CL:0000512]
xref: CL:0000512
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2009-07-20T02:17:10Z

[Term]
id: XAO:0003264
name: pericyte
namespace: xenopus_anatomy
def: "A slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [CL:0000669]
xref: CL:0000669
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: eriksegerdell
creation_date: 2009-07-20T02:21:51Z

[Term]
id: XAO:0003265
name: somatic stem cell
namespace: xenopus_anatomy
def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [CL:0000723]
xref: CL:0000723
is_a: XAO:0003054 ! stem cell
created_by: eriksegerdell
creation_date: 2009-07-20T02:25:31Z

[Term]
id: XAO:0003266
name: liver primordium
namespace: xenopus_anatomy
def: "Embryonic primordium consisting of an endodermal thickening that develops into the liver." [XAO:EJS, ZFA:0000124]
synonym: "liver" BROAD []
synonym: "liver bud" RELATED []
xref: UBERON:0003894
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2009-07-20T04:05:12Z

[Term]
id: XAO:0003267
name: kidney
namespace: xenopus_anatomy
def: "Either of the pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine. Amphibians (and fish) have a early kidney, the pronephros/pronephric kidney, which consitsts of a single nephron attached to a pronephric duct, which in turn is linked to the cloaca. The pronephros functions as primary filtration system for the embryo while the mesonephric kidney develops. The pronephros starts to degenerate at NF stage 53. The mesonephros starts to form at NF stage 39 and contuinues to grow into the adult kidney." [AAO:0000250, XAO:curators]
xref: UBERON:0002113
is_a: XAO:0003165 ! cavitated compound organ
relationship: develops_from XAO:0000085 ! intermediate mesoderm
relationship: part_of XAO:0000143 ! urinary system
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell
creation_date: 2009-08-25T11:34:29Z

[Term]
id: XAO:0003268
name: cardiac progenitor cell
namespace: xenopus_anatomy
def: "Type of presumptive precardiac cell that lie as paired primordia 30 to 45 degrees on either side of the dorsal midline of the embryo. As gastrulation proceeds, these migrate laterally, eventually fusing at the anterior ventral midline, where they differentiate into cardiac tissue. They give rise to the linear heart tube of the fused heart primordium and derive from the cardiac crescent." [PMID:17194606, PMID:2340810]
synonym: "CPC" EXACT []
is_a: XAO:0005033 ! progenitor cell
relationship: end_stage XAO:1000035 ! NF stage 19
relationship: part_of XAO:0000336 ! fused heart primordium
relationship: start_stage XAO:1000024 ! NF stage 14
created_by: eriksegerdell
creation_date: 2009-12-01T04:42:20Z

[Term]
id: XAO:0003269
name: jaw muscle
namespace: xenopus_anatomy
def: "Type of muscle that arises in the zygomatic arch and closes the jaw." [UBERON:0003681]
xref: UBERON:0011648
is_a: XAO:0004322 ! cranial muscle
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2009-12-01T04:45:17Z

[Term]
id: XAO:0004000
name: duct
namespace: xenopus_anatomy
def: "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination." [UBERON:0000058]
synonym: "ducts" RELATED PLURAL []
xref: UBERON:0000058
is_a: XAO:0003037 ! multi-tissue structure
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: lab
creation_date: 2011-06-16T10:41:29Z

[Term]
id: XAO:0004001
name: portion of organism substance
namespace: xenopus_anatomy
def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [CARO:0000004]
xref: UBERON:0000463
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: end_stage XAO:0000437 ! death
relationship: start_stage XAO:1000001 ! NF stage 1
created_by: lab
creation_date: 2011-06-16T10:56:39Z

[Term]
id: XAO:0004002
name: lateral line
namespace: xenopus_anatomy
def: "Any of the sense organs that detect vibrations carried through water. They develop from a specialized series of dorsolateral ectodermal placodes named lateral line placodes." [XAO:EJS]
xref: UBERON:0010202
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000095 ! lateral line system
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: lab
creation_date: 2011-06-16T11:03:34Z

[Term]
id: XAO:0004003
name: anatomical line
namespace: xenopus_anatomy
def: "Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface." [CARO:0000008]
xref: CARO:0000008
xref: UBERON:0006800
is_a: XAO:0000000 ! Xenopus anatomical entity
relationship: end_stage XAO:0000437 ! death
relationship: start_stage XAO:1000083 ! oocyte stage I
created_by: lab
creation_date: 2011-06-16T11:18:59Z

[Term]
id: XAO:0004004
name: atypical epithelium
namespace: xenopus_anatomy
def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [AAO:0010057]
xref: CARO:0000071
xref: UBERON:0000488
is_a: XAO:0003045 ! epithelium
created_by: lab
creation_date: 2011-06-20T10:55:41Z

[Term]
id: XAO:0004005
name: extraembryonic structure
namespace: xenopus_anatomy
def: "Anatomical structure that is contiguous with the embryo and comprises portions of tissue or cells that will not contribute to the embryo." [XAO:EJS, ZFA:0000020]
xref: CARO:0000042
xref: UBERON:0000478
is_a: XAO:0003000 ! anatomical structure
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0003004 ! whole organism
created_by: lab
creation_date: 2011-06-20T11:00:46Z

[Term]
id: XAO:0004006
name: multilaminar epithelium
namespace: xenopus_anatomy
def: "Epithelium that consists of more than one layer of epithelial cells." [CARO:0000069]
xref: CARO:0000069
xref: UBERON:0000486
is_a: XAO:0003045 ! epithelium
created_by: lab
creation_date: 2011-06-20T11:10:18Z

[Term]
id: XAO:0004007
name: unilaminar epithelium
namespace: xenopus_anatomy
def: "Epithelium that consists of a single layer of epithelial cells." [CARO:MAH]
xref: CARO:0000073
xref: UBERON:0000490
is_a: XAO:0003045 ! epithelium
created_by: lab
creation_date: 2011-06-20T11:18:11Z

[Term]
id: XAO:0004008
name: simple columnar epithelium
namespace: xenopus_anatomy
def: "Unilaminar epithelium that consists of a single layer of columnar cells." [CARO:MAH]
xref: CARO:0000068
xref: UBERON:0000485
is_a: XAO:0004007 ! unilaminar epithelium
created_by: lab
creation_date: 2011-06-20T11:19:24Z

[Term]
id: XAO:0004009
name: simple cuboidal epithelium
namespace: xenopus_anatomy
def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [CARO:MAH]
xref: CARO:0000067
xref: UBERON:0000484
is_a: XAO:0004007 ! unilaminar epithelium
created_by: lab
creation_date: 2011-06-20T11:22:50Z

[Term]
id: XAO:0004010
name: simple squamous epithelium
namespace: xenopus_anatomy
def: "Unilaminar epithelium that consists of a single layer of squamous cells." [CARO:MAH]
xref: CARO:0000070
xref: UBERON:0000487
is_a: XAO:0004007 ! unilaminar epithelium
created_by: lab
creation_date: 2011-06-20T11:25:42Z

[Term]
id: XAO:0004011
name: axial skeleton
namespace: xenopus_anatomy
def: "Anatomical cluster of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum." [VSAO:0000056]
xref: UBERON:0005944
is_a: XAO:0004289 ! skeletal subdivision
relationship: develops_from XAO:0000058 ! somite
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-22T02:37:32Z

[Term]
id: XAO:0004012
name: skeletal element
namespace: xenopus_anatomy
def: "Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages." [VSAO:0000128]
xref: UBERON:0004765
is_a: XAO:0003164 ! solid compound organ
relationship: part_of XAO:0004053 ! skeleton
relationship: start_stage XAO:1000040 ! NF stage 24
created_by: xenbase3
creation_date: 2011-08-22T03:11:53Z

[Term]
id: XAO:0004013
name: cartilage element
namespace: xenopus_anatomy
def: "Skeletal element that is composed of cartilage tissue and may be permanent or transient." [UBERON:0007844]
synonym: "cartilage" RELATED []
synonym: "cartilaginous element" EXACT []
synonym: "chondrogenic element" EXACT []
xref: UBERON:0007844
is_a: XAO:0004012 ! skeletal element
relationship: develops_from XAO:0004022 ! cartilaginous condensation
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: xenbase3
creation_date: 2011-08-22T03:25:09Z

[Term]
id: XAO:0004014
name: membrane bone
namespace: xenopus_anatomy
def: "Bone element that arises as a result of intramembranous ossification." [UBERON:0007842]
xref: UBERON:0007842
is_a: XAO:0004276 ! bone element
created_by: xenbase3
creation_date: 2011-08-22T03:36:02Z

[Term]
id: XAO:0004015
name: dermal bone
namespace: xenopus_anatomy
def: "Skeletal element that forms superficially in the organism, usually in association with the ectoderm." [UBERON:0008907]
xref: UBERON:0008907
is_a: XAO:0004014 ! membrane bone
relationship: part_of XAO:0004025 ! dermal skeleton
created_by: xenbase3
creation_date: 2011-08-22T03:36:25Z

[Term]
id: XAO:0004016
name: replacement element
namespace: xenopus_anatomy
def: "Skeletal element that forms as a replacement or substitution of another element or tissue." [UBERON:0010522]
xref: UBERON:0010522
is_a: XAO:0004012 ! skeletal element
relationship: part_of XAO:0004026 ! endoskeleton
relationship: start_stage XAO:1000055 ! NF stage 43
created_by: xenbase3
creation_date: 2011-08-22T03:37:56Z

[Term]
id: XAO:0004017
name: endochondral element
namespace: xenopus_anatomy
def: "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." [UBERON:0010363]
synonym: "endochondral replacement element" EXACT []
xref: UBERON:0010363
is_a: XAO:0004016 ! replacement element
created_by: xenbase3
creation_date: 2011-08-22T03:38:45Z

[Term]
id: XAO:0004018
name: endochondral bone
namespace: xenopus_anatomy
def: "Replacement bone that forms within cartilage." [UBERON:0002513]
synonym: "ossified chondrogenic bone" EXACT []
xref: UBERON:0002513
is_a: XAO:0004017 ! endochondral element
relationship: develops_from XAO:0004022 ! cartilaginous condensation
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-22T03:39:53Z

[Term]
id: XAO:0004019
name: vertebra
namespace: xenopus_anatomy
def: "Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum." [AAO:0000691]
synonym: "vertebrae" RELATED PLURAL []
xref: UBERON:0002412
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003074 ! vertebral column
created_by: xenbase3
creation_date: 2011-08-22T03:44:24Z

[Term]
id: XAO:0004020
name: process
namespace: xenopus_anatomy
def: "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, or fin." [VSAO:0000180]
synonym: "bony projection" RELATED []
synonym: "flange" EXACT []
synonym: "lamellae" EXACT []
synonym: "laminae" EXACT []
synonym: "projection" EXACT []
synonym: "ridge" EXACT []
synonym: "shelf" EXACT []
xref: UBERON:0004529
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003000 ! anatomical structure
relationship: develops_from XAO:0000113 ! embryo
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-22T03:58:55Z

[Term]
id: XAO:0004021
name: cell condensation
namespace: xenopus_anatomy
def: "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration." [PMID:8901191, UBERON:0011585]
xref: UBERON:0011585
is_a: XAO:0003000 ! anatomical structure
relationship: part_of XAO:0003004 ! whole organism
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-22T04:26:10Z

[Term]
id: XAO:0004022
name: cartilaginous condensation
namespace: xenopus_anatomy
def: "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." [UBERON:0005863]
synonym: "cartilage condensation" EXACT []
synonym: "chondrogenic condensation" EXACT []
xref: UBERON:0005863
is_a: XAO:0004021 ! cell condensation
relationship: part_of XAO:0004053 ! skeleton
created_by: xenbase3
creation_date: 2011-08-22T04:27:08Z

[Term]
id: XAO:0004023
name: craniofacial skeleton
namespace: xenopus_anatomy
def: "Cranial skeleton derived from neural crest cells." [VSAO:00000082]
synonym: "cranio-facial skeleton" EXACT []
is_a: XAO:0004279 ! cranial skeleton
relationship: develops_from XAO:0001001 ! cranial neural crest
created_by: xenbase3
creation_date: 2011-08-22T04:39:54Z

[Term]
id: XAO:0004024
name: craniofacial region
namespace: xenopus_anatomy
def: "Anatomical cluster that encompasses the cranium and facial structures." [XAO:EJS]
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: xenbase3
creation_date: 2011-08-22T04:42:44Z

[Term]
id: XAO:0004025
name: dermal skeleton
namespace: xenopus_anatomy
def: "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." [UBERON:0010364]
synonym: "dermal skeletal system" RELATED []
synonym: "dermoskeleton" RELATED []
synonym: "desmoskeleton" RELATED []
synonym: "exoskeleton" RELATED []
xref: UBERON:0010364
is_a: XAO:0004289 ! skeletal subdivision
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-22T04:47:40Z

[Term]
id: XAO:0004026
name: endoskeleton
namespace: xenopus_anatomy
def: "Skeletal system that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues." [UBERON:0010362]
synonym: "replacement skeleton" EXACT []
xref: UBERON:0010362
is_a: XAO:0004289 ! skeletal subdivision
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-22T04:49:15Z

[Term]
id: XAO:0004027
name: extracellular matrix
namespace: xenopus_anatomy
def: "Anatomical structure composed of a combination of protein fibers, ground substance and tissue fluid; typically has embedded cells." [VSAO:0000022]
synonym: "ECM" EXACT []
is_a: XAO:0003162 ! acellular anatomical structure
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-22T04:52:15Z

[Term]
id: XAO:0004028
name: fibrocartilage
namespace: xenopus_anatomy
def: "Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns." [UBERON:0001995]
synonym: "fibrocartilage tissue" EXACT []
xref: UBERON:0001995
is_a: XAO:0000170 ! cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T04:54:35Z

[Term]
id: XAO:0004029
name: hyaline cartilage tissue
namespace: xenopus_anatomy
def: "Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance." [UBERON:0001994]
synonym: "hyaline cartilage" EXACT []
xref: UBERON:0001994
is_a: XAO:0000170 ! cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T04:56:37Z

[Term]
id: XAO:0004030
name: dense regular connective tissue
namespace: xenopus_anatomy
def: "Connective tissue that is dominated by collagen fibers organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)." [UBERON:0007846]
synonym: "dense fibrous connective tissue" EXACT []
synonym: "dense regular collagenous connective tissue" EXACT []
synonym: "dense regular collagenous tissue" EXACT []
synonym: "regular dense connective tissue" EXACT []
xref: UBERON:0007846
is_a: XAO:0001017 ! connective tissue
created_by: xenbase3
creation_date: 2011-08-22T05:06:10Z

[Term]
id: XAO:0004031
name: ligament
namespace: xenopus_anatomy
def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [UBERON:0000211]
xref: UBERON:0000211
is_a: XAO:0004030 ! dense regular connective tissue
created_by: xenbase3
creation_date: 2011-08-22T05:06:59Z

[Term]
id: XAO:0004032
name: proteinaceous extracellular matrix
namespace: xenopus_anatomy
def: "A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity." [VSAO:0000021]
is_a: XAO:0004027 ! extracellular matrix
created_by: xenbase3
creation_date: 2011-08-22T05:12:13Z

[Term]
id: XAO:0004033
name: avascular GAG-rich matrix
namespace: xenopus_anatomy
def: "Proteinaceous extracellular matrix that is avascular and consists primarily of glycosaminoglycans." [VSAO:0000059]
synonym: "avascular glycosaminoglycan-rich matrix" EXACT []
synonym: "cartilage matrix" EXACT []
synonym: "cartilage-like matrix" EXACT []
is_a: XAO:0004032 ! proteinaceous extracellular matrix
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-22T05:14:07Z

[Term]
id: XAO:0004034
name: mineralized extracellular matrix
namespace: xenopus_anatomy
def: "Extracellular matrix that is mineralized." [VSAO:0000020]
is_a: XAO:0004032 ! proteinaceous extracellular matrix
created_by: xenbase3
creation_date: 2011-08-22T05:16:11Z

[Term]
id: XAO:0004035
name: osteoid
namespace: xenopus_anatomy
def: "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue." [UBERON:0008883]
synonym: "osteoid tissue" EXACT []
synonym: "pre-bone" EXACT []
synonym: "prebone" EXACT []
synonym: "prebone tissue" EXACT []
xref: UBERON:0008883
is_a: XAO:0000169 ! bone tissue
is_a: XAO:0005000 ! matrix-based tissue
created_by: xenbase3
creation_date: 2011-08-22T05:17:00Z

[Term]
id: XAO:0004036
name: mineralized avascular GAG-rich matrix
namespace: xenopus_anatomy
def: "Avascular GAG-rich matrix that is mineralized." [VSAO:0000120]
is_a: XAO:0004033 ! avascular GAG-rich matrix
is_a: XAO:0004034 ! mineralized extracellular matrix
relationship: part_of XAO:0004055 ! mineralized cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T05:18:20Z

[Term]
id: XAO:0004037
name: non-mineralized avascular GAG-rich matrix
namespace: xenopus_anatomy
def: "Avascular GAG-rich matrix that is not mineralized." [VSAO:0000119]
synonym: "non-mineralized cartilage" EXACT []
is_a: XAO:0004033 ! avascular GAG-rich matrix
relationship: part_of XAO:0004043 ! non-mineralized cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T05:18:57Z

[Term]
id: XAO:0004038
name: skeletal tissue
namespace: xenopus_anatomy
def: "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support." [UBERON:0004755]
xref: UBERON:0004755
is_a: XAO:0001017 ! connective tissue
relationship: part_of XAO:0004012 ! skeletal element
created_by: xenbase3
creation_date: 2011-08-22T05:21:47Z

[Term]
id: XAO:0004039
name: mineralized tissue
namespace: xenopus_anatomy
def: "Skeletal tissue that is mineralized." [XAO:EJS]
is_a: XAO:0004038 ! skeletal tissue
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-22T05:22:34Z

[Term]
id: XAO:0004040
name: mineralized bone tissue
namespace: xenopus_anatomy
def: "Bone tissue mineralized with hydroxyapatite." [UBERON:4000115]
xref: UBERON:4000115
is_a: XAO:0000169 ! bone tissue
is_a: XAO:0004039 ! mineralized tissue
relationship: develops_from XAO:0004035 ! osteoid
created_by: xenbase3
creation_date: 2011-08-22T05:23:02Z

[Term]
id: XAO:0004041
name: mineralized hyaline cartilage tissue
namespace: xenopus_anatomy
def: "Hyaline cartilage tissue that is mineralized." [VSAO:0000109]
is_a: XAO:0004039 ! mineralized tissue
created_by: xenbase3
creation_date: 2011-08-22T05:25:19Z

[Term]
id: XAO:0004042
name: muscular system
namespace: xenopus_anatomy
def: "Anatomical system comprising the sum of all muscles in the body." [UBERON:0000383]
xref: UBERON:0000383
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0000168 ! musculoskeletal system
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: xenbase3
creation_date: 2011-08-22T05:28:16Z

[Term]
id: XAO:0004043
name: non-mineralized cartilage tissue
namespace: xenopus_anatomy
def: "Cartilage tissue that is not mineralized." [VSAO:0000089]
is_a: XAO:0000170 ! cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T05:30:58Z

[Term]
id: XAO:0004044
name: non-mineralized hyaline cartilage tissue
namespace: xenopus_anatomy
def: "Hyaline cartilage tissue that is not mineralized." [VSAO:0000108]
is_a: XAO:0004029 ! hyaline cartilage tissue
is_a: XAO:0004043 ! non-mineralized cartilage tissue
created_by: xenbase3
creation_date: 2011-08-22T05:32:35Z

[Term]
id: XAO:0004045
name: odontogenic papilla
namespace: xenopus_anatomy
def: "Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium." [VSAO:0000025]
synonym: "dental papilla" RELATED []
synonym: "odontogenic condensation" EXACT []
xref: UBERON:0001763
is_a: XAO:0004021 ! cell condensation
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-23T08:43:35Z

[Term]
id: XAO:0004046
name: odontoid tissue
namespace: xenopus_anatomy
def: "Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla." [UBERON:0010365]
synonym: "dental tissue" RELATED []
synonym: "odontogenic tissue" EXACT []
xref: UBERON:0010365
is_a: XAO:0004038 ! skeletal tissue
relationship: develops_from XAO:0004045 ! odontogenic papilla
relationship: part_of XAO:0004025 ! dermal skeleton
relationship: start_stage XAO:1000072 ! NF stage 60
created_by: xenbase3
creation_date: 2011-08-23T08:45:58Z

[Term]
id: XAO:0004047
name: oropharyngeal papilla
namespace: xenopus_anatomy
def: "Odontogenic papilla located along the jaws or pharyngeal skeleton." [VSAO:0000030]
synonym: "oropharyngeal dental papilla" EXACT []
is_a: XAO:0004045 ! odontogenic papilla
created_by: xenbase3
creation_date: 2011-08-23T08:47:31Z

[Term]
id: XAO:0004048
name: oropharynx
namespace: xenopus_anatomy
def: "Anatomical cluster that comprises the oral part of the pharynx." [UBERON:0001729]
xref: UBERON:0001729
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003227 ! pharynx
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-23T08:50:17Z

[Term]
id: XAO:0004049
name: perichondrium
namespace: xenopus_anatomy
def: "A layer of dense irregular connective tissue that surrounds the cartilage of developing bone, consisting of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes. Perichondrium is a type of  connective tissue, and also functions in the growth and repair of cartilage. Once vascularized, the perichondrium becomes the periosteum." [http://en.wikipedia.org/wiki/Perichondrium]
xref: UBERON:0002222
is_a: XAO:0001017 ! connective tissue
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-23T08:52:43Z

[Term]
id: XAO:0004050
name: perichordal tissue
namespace: xenopus_anatomy
def: "Fibrous connective tissue that surrounds the notochord; includes a layer of elastin." [UBERON:0007862]
synonym: "notochord" RELATED []
synonym: "perichordal connective tissue" EXACT []
synonym: "perichordal sheath" EXACT []
synonym: "perichordal sheath tissue" EXACT []
xref: UBERON:0007862
is_a: XAO:0001017 ! connective tissue
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: part_of XAO:0000055 ! notochord
created_by: xenbase3
creation_date: 2011-08-23T08:53:53Z

[Term]
id: XAO:0004051
name: dentine
namespace: xenopus_anatomy
def: "Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular." [UBERON:0001751]
synonym: "dental tissue" RELATED []
xref: UBERON:0001751
is_a: XAO:0004046 ! odontoid tissue
relationship: develops_from XAO:0004052 ! pre-dentine
created_by: xenbase3
creation_date: 2011-08-23T08:56:47Z

[Term]
id: XAO:0004052
name: pre-dentine
namespace: xenopus_anatomy
def: "Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix." [UBERON:0011587]
synonym: "pre-dentine tissue" EXACT []
synonym: "predentine tissue" EXACT []
xref: UBERON:0011587
is_a: XAO:0004046 ! odontoid tissue
created_by: xenbase3
creation_date: 2011-08-23T08:58:05Z

[Term]
id: XAO:0004053
name: skeleton
namespace: xenopus_anatomy
def: "Anatomical cluster that consists of all the skeletal elements (eg, bone, cartilage, and teeth) of the body." [UBERON:0004288]
xref: UBERON:0004288
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0003060 ! skeletal system
relationship: start_stage XAO:1000040 ! NF stage 24
created_by: xenbase3
creation_date: 2011-08-23T09:00:02Z

[Term]
id: XAO:0004054
name: vacuolated notochordal tissue
namespace: xenopus_anatomy
def: "Connective tissue that is matrix-poor with large number of vacuolated cells." [VSAO:0000053]
synonym: "notochord proper" EXACT []
is_a: XAO:0001017 ! connective tissue
relationship: end_stage XAO:1000074 ! NF stage 62
relationship: part_of XAO:0000055 ! notochord
created_by: xenbase3
creation_date: 2011-08-23T09:02:51Z

[Term]
id: XAO:0004055
name: mineralized cartilage tissue
namespace: xenopus_anatomy
def: "Cartilage tissue that is mineralized." [VSAO:0000088]
is_a: XAO:0000170 ! cartilage tissue
created_by: xenbase3
creation_date: 2011-08-23T09:31:53Z

[Term]
id: XAO:0004056
name: distal mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme cells that proliferate in the progress zone of developing limb buds." [XAO:EJS]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: xenbase3
creation_date: 2011-08-24T10:22:39Z

[Term]
id: XAO:0004057
name: tail tip
namespace: xenopus_anatomy
def: "Portion of tissue comprising the posterior end of the tail fin." [XAO:EJS]
xref: UBERON:0010162
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004062 ! tail fin
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: xenbase3
creation_date: 2011-08-24T10:30:32Z

[Term]
id: XAO:0004058
name: ampullary nerve
namespace: xenopus_anatomy
def: "Nerve that is a branch of cranial nerve VIII and innervates the cristae ampullaris." [XAO:EJS, ZFA:0005144]
synonym: "neural ampulla" EXACT []
is_a: XAO:0003047 ! nerve
relationship: part_of XAO:0003095 ! vestibulocochlear nerve
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: xenbase3
creation_date: 2011-08-24T10:33:59Z

[Term]
id: XAO:0004059
name: regenerating tissue
namespace: xenopus_anatomy
def: "A portion of tissue that is re-growing after damage or amputation." [XAO:EJS, ZFA:0005147]
xref: UBERON:0007567
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-24T10:40:19Z

[Term]
id: XAO:0004060
name: blastema
namespace: xenopus_anatomy
def: "A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise." [XAO:EJS, ZFA:0001270]
xref: UBERON:0005306
is_a: XAO:0004059 ! regenerating tissue
relationship: start_stage XAO:1000061 ! NF stage 49
created_by: xenbase3
creation_date: 2011-08-24T10:42:35Z

[Term]
id: XAO:0004061
name: dorsal fin margin
namespace: xenopus_anatomy
def: "Fin margin which is part of the dorsal fin." [XAO:EJS]
is_a: XAO:0005171 ! fin margin
relationship: part_of XAO:0000469 ! dorsal tail fin
relationship: part_of XAO:0004063 ! dorsal fin
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: xenbase3
creation_date: 2011-08-24T10:45:04Z

[Term]
id: XAO:0004062
name: tail fin
namespace: xenopus_anatomy
def: "The fin at the posterior part of the body of the tadpole." [BTO:0001827]
synonym: "caudal fin" RELATED []
is_a: XAO:0000002 ! fin
relationship: part_of XAO:0003026 ! tail
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: xenbase3
creation_date: 2011-08-24T10:47:44Z

[Term]
id: XAO:0004063
name: dorsal fin
namespace: xenopus_anatomy
def: "The unsupported flaps of epidermis-covered, loose connective tissue extending the length of the dorsal tail muscle, originating at or near the tail-body junction, and extending posteriorly to slightly beyond the tip of the notochord and tail musculature." [ISBN:0226557634]
is_a: XAO:0000002 ! fin
created_by: xenbase3
creation_date: 2011-08-24T10:57:00Z

[Term]
id: XAO:0004064
name: ventral tail fin
namespace: xenopus_anatomy
def: "The ventral part of the tail fin." [XAO:EJS]
is_a: XAO:0000002 ! fin
relationship: part_of XAO:0004062 ! tail fin
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: xenbase3
creation_date: 2011-08-24T11:06:36Z

[Term]
id: XAO:0004065
name: ventral fin margin
namespace: xenopus_anatomy
def: "Fin margin which is part of the ventral fin." [XAO:EJS]
is_a: XAO:0005171 ! fin margin
relationship: part_of XAO:0004064 ! ventral tail fin
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: xenbase3
creation_date: 2011-08-24T11:08:17Z

[Term]
id: XAO:0004066
name: vegetal endoderm
namespace: xenopus_anatomy
def: "Portion of the cleavage-stage embryo below the equator and consisting of prospective endodermal cells." [ISBN:0123646200]
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000020 ! NF stage 10
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell)
created_by: xenbase3
creation_date: 2011-08-24T11:12:31Z

[Term]
id: XAO:0004067
name: suprablastoporal endoderm
namespace: xenopus_anatomy
def: "During gastrulation, the ring of endodermal cells that overlie the larger sub-blastoral endoderm cells." [ISBN:0123646200]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000033 ! NF stage 12.5
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-24T11:14:55Z

[Term]
id: XAO:0004068
name: sub-blastoporal endoderm
namespace: xenopus_anatomy
def: "During gastrulation, the vegetal endodermal cells that lie just below the ring of smaller suprablastoral endoderm cells." [ISBN:0123646200]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000033 ! NF stage 12.5
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-24T11:15:44Z

[Term]
id: XAO:0004069
name: migratory neural crest cell
namespace: xenopus_anatomy
def: "Neural crest that lose their connections to other neuroepithelial cells during the delamination process and begin to migrate. This involves either partial or complete epithelial-to-mesenchymal transition. Numerous molecules have been demonstrated to guide a neural crest cell's migration to its target tissue." [XAO:CJZ]
synonym: "migratory neural crest" RELATED []
synonym: "migratory neural crest cells" RELATED PLURAL []
synonym: "NCMC" RELATED []
synonym: "neural crest migrating cells" RELATED PLURAL []
xref: CL:0000333
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000048 ! neural crest
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: xenbase3
creation_date: 2011-08-24T11:22:55Z

[Term]
id: XAO:0004070
name: hypothalamus
namespace: xenopus_anatomy
def: "Multi-tissue structure that is part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system." [AAO:0010484]
xref: UBERON:0001898
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-24T11:29:04Z

[Term]
id: XAO:0004071
name: optic chiasm
namespace: xenopus_anatomy
def: "Decussation of cranial nerve II axons whereby some cross the midline and some remain ipsilateral." [XAO:EJS, ZFA:0000556]
synonym: "OC" EXACT []
synonym: "optic chiasma" EXACT []
xref: UBERON:0000959
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-24T11:35:57Z

[Term]
id: XAO:0004072
name: suprachiasmatic nucleus
namespace: xenopus_anatomy
def: "The ventral region of the alar hypothalamus. It is a diencephalic nucleus that is part of the preoptic area and is ventrolateral to the caudal parvocellular preoptic nucleus." [PMID:24122702, XAO:EJS, ZFA:0000441]
synonym: "SC" EXACT []
synonym: "suprachiasmatic region" RELATED []
xref: UBERON:0002034
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004230 ! anterior hypothalamus
relationship: start_stage XAO:1000047 ! NF stage 32
created_by: xenbase3
creation_date: 2011-08-24T11:41:40Z

[Term]
id: XAO:0004074
name: intersomitic region
namespace: xenopus_anatomy
def: "Anatomical region between somites." [XAO:EJS]
synonym: "intersomitic junction" EXACT []
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: start_stage XAO:1000027 ! NF stage 17
created_by: xenbase3
creation_date: 2011-08-24T12:21:44Z

[Term]
id: XAO:0004075
name: intersomitic vessel
namespace: xenopus_anatomy
def: "Primary blood vessel sprouts that originate from the aorta and grow dorsally between the somites." [PMID:17119151]
synonym: "intersomitic blood vessel" EXACT []
is_a: XAO:0001011 ! blood vessel
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0004074 ! intersomitic region
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-24T12:25:46Z

[Term]
id: XAO:0004076
name: intersomitic tendon
namespace: xenopus_anatomy
def: "A tendon located in the intersomitic region." [XAO:EJS]
is_a: XAO:0000173 ! tendon
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0004074 ! intersomitic region
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: xenbase3
creation_date: 2011-08-24T12:28:10Z

[Term]
id: XAO:0004077
name: intersomitic epithelium
namespace: xenopus_anatomy
def: "Epithelium located in the intersomitic region." [XAO:EJS]
synonym: "intersomitic membrane" EXACT []
is_a: XAO:0003045 ! epithelium
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0004074 ! intersomitic region
relationship: start_stage XAO:1000027 ! NF stage 17
created_by: xenbase3
creation_date: 2011-08-24T12:31:19Z

[Term]
id: XAO:0004078
name: intersomitic neuron
namespace: xenopus_anatomy
def: "Neuron located in the intersomitic region." [XAO:EJS]
is_a: XAO:0003023 ! neuron
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0004074 ! intersomitic region
relationship: start_stage XAO:1000027 ! NF stage 17
created_by: xenbase3
creation_date: 2011-08-24T12:34:45Z

[Term]
id: XAO:0004079
name: rhombomere
namespace: xenopus_anatomy
def: "Any of the transient sequential subdivisions of the developing hindbrain, all posterior to the midbrain-hindbrain boundary." [XAO:EJS]
synonym: "rhombomeres" RELATED PLURAL []
xref: UBERON:0001892
is_a: XAO:0004597 ! neuromere
relationship: develops_from XAO:0005026 ! presumptive rhombomere
relationship: part_of XAO:0000015 ! hindbrain
created_by: xenbase3
creation_date: 2011-08-24T01:19:56Z

[Term]
id: XAO:0004080
name: rhombomere R2
namespace: xenopus_anatomy
def: "The 2nd most anterior segment of the developing hindbrain, which along with r3 is dorsal to brancial arch 1." [XAO:curators]
synonym: "r2" EXACT []
synonym: "rhombomere 2" EXACT []
xref: UBERON:0005569
is_a: XAO:0004079 ! rhombomere
created_by: xenbase3
creation_date: 2011-08-24T02:00:45Z

[Term]
id: XAO:0004081
name: rhombomere R3
namespace: xenopus_anatomy
def: "The 3rd segment of the developing hindbrain, between rhombomeres r2 and r4, which along with r2 is dorsal to branchial arch 1." [XAO:curators]
synonym: "r3" EXACT []
synonym: "rhombomere 3" EXACT []
xref: UBERON:0005507
is_a: XAO:0004079 ! rhombomere
created_by: xenbase3
creation_date: 2011-08-24T02:04:40Z

[Term]
id: XAO:0004082
name: rhombomere R4
namespace: xenopus_anatomy
def: "The 4th segment of the developing hindbrain, between rhombomeres r3 and r5 and dorsal to branchial arch 2." [XAO:curators]
synonym: "r4" EXACT []
synonym: "rhombomere 4" EXACT []
xref: UBERON:0005511
is_a: XAO:0004079 ! rhombomere
created_by: xenbase3
creation_date: 2011-08-24T02:06:25Z

[Term]
id: XAO:0004083
name: rhombomere R5
namespace: xenopus_anatomy
def: "The 5th segment of the developing hindbrain, between rhombomeres r4 and r6, and dorsal to branchial arch 3." [XAO:curators]
synonym: "r5" EXACT []
synonym: "rhombomere 5" EXACT []
xref: UBERON:0005515
is_a: XAO:0004079 ! rhombomere
created_by: xenbase3
creation_date: 2011-08-24T02:08:06Z

[Term]
id: XAO:0004084
name: rhombomere R6
namespace: xenopus_anatomy
def: "The 6th segment of the developing hindbrain, directly bordering the midbrain-hindbrain boundary, and dorsal to branchial arch 4." [XAO:curators]
synonym: "r6" EXACT []
synonym: "rhombomere 6" EXACT []
xref: UBERON:0005519
is_a: XAO:0004079 ! rhombomere
created_by: xenbase3
creation_date: 2011-08-24T02:09:39Z

[Term]
id: XAO:0004085
name: ionocyte
namespace: xenopus_anatomy
def: "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In Xenopus there are two distinct types of ionocytes, described as alpha- and beta- subtypes." [CL:0005006]
synonym: "clear cell" BROAD []
synonym: "FORE cell" RELATED []
synonym: "IC" EXACT []
synonym: "intercalated cell" BROAD []
synonym: "mitochondria-rich cell" BROAD []
synonym: "narrow cell" BROAD []
synonym: "proton-secreting cell" RELATED []
synonym: "PSC" RELATED []
xref: CL:0005006
is_a: XAO:0004225 ! non-ciliated epithelial cell
relationship: part_of XAO:0000028 ! epidermis
relationship: part_of XAO:0004091 ! non-neural ectoderm
created_by: xenbase3
creation_date: 2011-08-24T02:12:18Z

[Term]
id: XAO:0004086
name: presumptive midbrain-hindbrain boundary
namespace: xenopus_anatomy
def: "Part of the neural ectoderm that will become the embryonic midbrain-hindbrain boundary." [UBERON:0007281]
xref: UBERON:0007281
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000215 ! central nervous system
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: xenbase3
creation_date: 2011-08-24T02:24:16Z

[Term]
id: XAO:0004087
name: neural fold
namespace: xenopus_anatomy
def: "One of the two edges of the neural groove." [UBERON:0005062]
xref: UBERON:0005062
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000042 ! neuroectoderm
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: xenbase3
creation_date: 2011-08-24T02:42:38Z

[Term]
id: XAO:0004088
name: animal pole
namespace: xenopus_anatomy
def: "The apical region of the animal hemisphere." [XAO:curator]
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000021 ! NF stage 11
relationship: part_of XAO:0000202 ! animal hemisphere
created_by: xenbase3
creation_date: 2011-08-24T03:18:10Z

[Term]
id: XAO:0004089
name: periocular region
namespace: xenopus_anatomy
def: "Anatomical region that surrounds the eye but is within the orbit." [http://www.merriam-webster.com/medical/periocular]
synonym: "periocular mesenchyme" RELATED []
xref: UBERON:0004017
is_a: XAO:0003186 ! anatomical region
relationship: part_of XAO:0000040 ! head region
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: xenbase3
creation_date: 2011-08-24T03:20:21Z

[Term]
id: XAO:0004090
name: optic field
namespace: xenopus_anatomy
def: "Portion of tissue that is part of the anterior neural plate and will form the optic vesicle." [XAO:EJS, ZFA:0000570]
synonym: "eye primordium" RELATED []
synonym: "optic primordium" RELATED []
xref: UBERON:0003071
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000024 ! NF stage 14
relationship: part_of XAO:0000045 ! pre-chordal neural plate
relationship: start_stage XAO:1000033 ! NF stage 12.5
created_by: xenbase3
creation_date: 2011-08-24T03:24:00Z

[Term]
id: XAO:0004091
name: non-neural ectoderm
namespace: xenopus_anatomy
def: "The portion of the embryonic ectoderm, including the preplacodal ectoderm, that does not give rise to nervous tissue." [XAO:EJS]
synonym: "NNE" EXACT []
xref: UBERON:0005497
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0004132 ! presumptive ectoderm
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000001 ! ectoderm
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: xenbase3
creation_date: 2011-08-24T03:28:19Z

[Term]
id: XAO:0004092
name: preplacodal ectoderm
namespace: xenopus_anatomy
def: "A thick, U-shaped primordium positioned at the border of the future epidermis and the neural plate/neural crest forming regions, in the neural stage embryo. This field of naive ectoderm is subdivided into 3 domains, each with distinct gene expression profiles: the anterior PPE (bottom of the U), the lateral PPE (the curves of the U), and the posterior PPE (arms of the U and adjacent to the neural crest/neural plate border). The PPE differentiates into the sensory placodes, which in turn form the adenohypophysis/anterior pituitary gland and sensory organs (such as the olfactory epithelium, lens, trigeminal nerves, epibranchial nerves, otic vesicles and lateral lines)." [PMID:30291163]
synonym: "PPE" EXACT []
synonym: "pre-placodal ectoderm" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm
relationship: develops_from XAO:0004104 ! neural plate border
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000270 ! sensorial layer of neurectoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5
created_by: xenbase3
creation_date: 2011-08-24T03:30:53Z

[Term]
id: XAO:0004093
name: profundal placode
namespace: xenopus_anatomy
def: "An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24." [PMID:21452441]
synonym: "profundus placode" EXACT []
is_a: XAO:0004620 ! neurogenic placode
relationship: end_stage XAO:1000045 ! NF stage 29 and 30
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-24T03:36:24Z

[Term]
id: XAO:0004094
name: lens epithelium
namespace: xenopus_anatomy
def: "Epithelium that borders the anterior and equitorial region of the lens. Lens growth occurs via the differentiation of additional fibre cells from lens epithelial cells." [XAO:EJS, ZFA:0001326]
xref: UBERON:0001803
is_a: XAO:0003045 ! epithelium
relationship: part_of XAO:0000008 ! lens
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-24T03:40:12Z

[Term]
id: XAO:0004095
name: lens transitional zone
namespace: xenopus_anatomy
def: "The region of the lens of the eye where cells from the anterior epithelial capsule become transformed into the fibers that compose the lens substance." [http://dictionary.reference.com/browse/transitional+zone]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000008 ! lens
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-24T03:43:21Z

[Term]
id: XAO:0004096
name: lens fiber cell mass
namespace: xenopus_anatomy
def: "Portion of tissue comprising fibers that form the bulk of the lens. They are long, thin, transparent cells." [UBERON:0002444]
synonym: "lens fiber" RELATED []
synonym: "lens fiber cells" RELATED []
xref: UBERON:0002444
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000008 ! lens
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: xenbase3
creation_date: 2011-08-24T03:45:09Z

[Term]
id: XAO:0004097
name: horizontal cell
namespace: xenopus_anatomy
def: "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." [CL:0000745]
synonym: "horizontal neuron" RELATED []
xref: CL:0000745
is_a: XAO:0003023 ! neuron
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-24T03:58:01Z

[Term]
id: XAO:0004098
name: bipolar neuron
namespace: xenopus_anatomy
def: "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body." [CL:0000103]
synonym: "bipolar cell" RELATED []
xref: CL:0000103
is_a: XAO:0004267 ! interneuron
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-24T04:01:16Z

[Term]
id: XAO:0004099
name: amacrine cell
namespace: xenopus_anatomy
def: "Interneuron of the retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons." [CL:0000561]
synonym: "amacrine neuron" EXACT []
xref: CL:0000561
is_a: XAO:0004267 ! interneuron
relationship: part_of XAO:0003216 ! retinal neural layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-24T04:06:40Z

[Term]
id: XAO:0004100
name: retinal ganglion cell
namespace: xenopus_anatomy
def: "Type of neuron that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [CL:0000740]
synonym: "RGC" EXACT []
xref: CL:0000740
is_a: XAO:0003023 ! neuron
relationship: part_of XAO:0003223 ! retinal ganglion cell layer
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: xenbase3
creation_date: 2011-08-24T04:08:45Z

[Term]
id: XAO:0004101
name: optic tract
namespace: xenopus_anatomy
def: "Diencephalic white matter (tract) that is composed of retinal ganglion cell axons after which they have passed through the optic chiasm." [UBERON:0001908]
xref: UBERON:0001908
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-25T09:25:47Z

[Term]
id: XAO:0004102
name: pre-chordal neural plate border
namespace: xenopus_anatomy
def: "The portion of the neural plate border that is anterior to the mid-hindbrain junction." [XAO:EJS]
synonym: "anterior neural plate border" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000045 ! pre-chordal neural plate
relationship: part_of XAO:0004104 ! neural plate border
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: xenbase3
creation_date: 2011-08-25T09:47:05Z

[Term]
id: XAO:0004103
name: chordal neural plate border
namespace: xenopus_anatomy
def: "The portion of the neural plate border that is posterior to the mid-hindbrain junction, and from which neural crest cells arise." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000046 ! chordal neural plate
relationship: part_of XAO:0004104 ! neural plate border
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: xenbase3
creation_date: 2011-08-25T09:47:56Z

[Term]
id: XAO:0004104
name: neural plate border
namespace: xenopus_anatomy
def: "The boundary between non-neural ectoderm and the neural plate of neurula stage embryos, giving rise to the neural crest and cranial placodes." [ISBN:0878933840]
synonym: "NPB" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000032 ! NF stage 11.5
created_by: xenbase3
creation_date: 2011-08-25T09:49:21Z

[Term]
id: XAO:0004105
name: pronephric tubule
namespace: xenopus_anatomy
def: "Any of bilaterally paired tubes that perform the resorptive and excretory functions of the pronephros, and which connect the pronephric glomeruli to the pronephric ducts." [ISBN:0127224416, ZFA:0001558]
xref: UBERON:0005310
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0000285 ! pronephric nephron
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: xenbase3
creation_date: 2011-08-25T09:56:54Z

[Term]
id: XAO:0004106
name: regenerating forelimb
namespace: xenopus_anatomy
def: "A portion of forelimb tissue that is re-growing after damage or amputation." [XAO:curators]
synonym: "forelimb" BROAD []
is_a: XAO:0004311 ! regenerating limb
created_by: xenbase3
creation_date: 2011-08-25T10:02:27Z

[Term]
id: XAO:0004107
name: regenerating hindlimb
namespace: xenopus_anatomy
def: "A portion of hind limb tissue that is re-growing after damage or amputation." [XAO:curators]
synonym: "hind limb" BROAD []
synonym: "hindlimb" BROAD []
synonym: "regenerating hind limb" EXACT []
is_a: XAO:0004311 ! regenerating limb
created_by: xenbase3
creation_date: 2011-08-25T10:02:56Z

[Term]
id: XAO:0004108
name: regenerating tail
namespace: xenopus_anatomy
def: "A portion of tail tissue that is re-growing after damage or amputation." [XAO:curators]
synonym: "tail" BROAD []
synonym: "tail blastema" RELATED []
is_a: XAO:0004059 ! regenerating tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000041 ! NF stage 25
created_by: xenbase3
creation_date: 2011-08-25T10:03:11Z

[Term]
id: XAO:0004109
name: regenerating eye
namespace: xenopus_anatomy
def: "A portion of eye tissue that is re-growing after damage or amputation." [XAO:curators]
synonym: "eye" BROAD []
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000034 ! NF stage 18
created_by: xenbase3
creation_date: 2011-08-25T10:03:22Z

[Term]
id: XAO:0004110
name: eye photoreceptor cell
namespace: xenopus_anatomy
def: "A cell found in the retina of the eye that is specialized to detect and transduce light." [CL:0000210]
xref: CL:0000287
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0003215 ! photoreceptor layer
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: xenbase3
creation_date: 2011-08-25T10:17:43Z

[Term]
id: XAO:0004111
name: retinal cone cell
namespace: xenopus_anatomy
def: "One of the two photoreceptor cell types in the retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [CL:0000573]
synonym: "cone photoreceptor cell" EXACT []
synonym: "eye photoreceptor cell (cone)" EXACT []
xref: CL:0000573
is_a: XAO:0004110 ! eye photoreceptor cell
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: xenbase3
creation_date: 2011-08-25T10:19:21Z

[Term]
id: XAO:0004112
name: retinal rod cell
namespace: xenopus_anatomy
def: "One of the two photoreceptor cell types of the retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [CL:0000604]
synonym: "eye photoreceptor cell (rod)" EXACT []
synonym: "rod photoreceptor cell" EXACT []
xref: CL:0000604
is_a: XAO:0004110 ! eye photoreceptor cell
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: xenbase3
creation_date: 2011-08-25T10:22:13Z

[Term]
id: XAO:0004113
name: vegetal pole
namespace: xenopus_anatomy
def: "The apical region of the vegetal hemisphere." [XAO:curator]
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000021 ! NF stage 11
relationship: part_of XAO:0000280 ! vegetal hemisphere
created_by: xenbase3
creation_date: 2011-08-25T10:25:07Z

[Term]
id: XAO:0004114
name: stage I oocyte
namespace: xenopus_anatomy
def: "A developing female gamete that is at the pre-vitellogenic stage." [XAO:curators]
synonym: "pre-vitellogenic oocyte" EXACT []
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000083 ! oocyte stage I
created_by: xenbase3
creation_date: 2011-08-25T10:27:57Z

[Term]
id: XAO:0004115
name: stage II oocyte
namespace: xenopus_anatomy
def: "A developing female gamete that is at the early vitellogenic stage." [XAO:curators]
synonym: "early vitellogenic oocyte" EXACT []
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000084 ! oocyte stage II
relationship: start_stage XAO:1000084 ! oocyte stage II
created_by: xenbase3
creation_date: 2011-08-25T10:28:59Z

[Term]
id: XAO:0004116
name: stage III oocyte
namespace: xenopus_anatomy
def: "A developing female gamete that is at the mid-vitellogenic stage." [XAO:curators]
synonym: "mid-vitellogenic oocyte" EXACT []
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000085 ! oocyte stage III
relationship: start_stage XAO:1000085 ! oocyte stage III
created_by: xenbase3
creation_date: 2011-08-25T10:30:01Z

[Term]
id: XAO:0004117
name: stage IV oocyte
namespace: xenopus_anatomy
def: "A developing female gamete that is at the stage in which polarization along the animal-vegetal axis is established." [XAO:curators]
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000086 ! oocyte stage IV
relationship: start_stage XAO:1000086 ! oocyte stage IV
created_by: xenbase3
creation_date: 2011-08-25T10:30:48Z

[Term]
id: XAO:0004118
name: stage V oocyte
namespace: xenopus_anatomy
def: "A developing female gamete that is at the late vitellogenic stage." [XAO:EJS]
synonym: "late vitellogenic oocyte" EXACT []
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000087 ! oocyte stage V
relationship: start_stage XAO:1000087 ! oocyte stage V
created_by: xenbase3
creation_date: 2011-08-25T10:31:45Z

[Term]
id: XAO:0004119
name: stage VI oocyte
namespace: xenopus_anatomy
def: "A female gamete that is at the fully grown stage." [XAO:EJS]
synonym: "post-vitellogenic oocyte" EXACT []
is_a: XAO:0000256 ! oocyte
relationship: end_stage XAO:1000088 ! oocyte stage VI
relationship: start_stage XAO:1000088 ! oocyte stage VI
created_by: xenbase3
creation_date: 2011-08-25T10:32:29Z

[Term]
id: XAO:0004120
name: cardiac jelly
namespace: xenopus_anatomy
def: "A sheet of extracellular matrix that separates the outer myocardial cell layer from the inner endocardial tube in the early embryonic heart. As the heart is going through the looping stages, this extracellular matrix/cardiac jelly starts to thicken in two regions, the atrioventricular canal region and the ventricular outflow tract region. These two discrete swellings of cardiac jelly are known as cardiac cushions. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates." [PMID:19890915]
xref: UBERON:0003906
is_a: XAO:0004027 ! extracellular matrix
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: xenbase3
creation_date: 2011-08-25T10:49:57Z

[Term]
id: XAO:0004121
name: apical ectodermal ridge
namespace: xenopus_anatomy
def: "A thickened layer of ectodermal cells at the distal tip of a developing limb bud. Along with the zone of polarizing activity, it is a crucial organizing region during limb development." [http://en.wikipedia.org/wiki/Apical_ectodermal_ridge]
synonym: "AER" EXACT []
synonym: "apical epidermal ridge" EXACT []
synonym: "epidermal ridge" EXACT []
xref: UBERON:0004356
is_a: XAO:0004122 ! proliferative region
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: xenbase3
creation_date: 2011-08-25T10:53:20Z

[Term]
id: XAO:0004122
name: proliferative region
namespace: xenopus_anatomy
def: "Anatomical cluster that consists of rapidly dividing cells." [XAO:EJS, ZFA:0000098]
is_a: XAO:0003160 ! anatomical cluster
relationship: start_stage XAO:1000018 ! NF stage 8
created_by: xenbase3
creation_date: 2011-08-25T10:57:21Z

[Term]
id: XAO:0004123
name: atrioventricular canal
namespace: xenopus_anatomy
def: "The part of the heart connecting the atrium to the cardiac ventricle." [PMID:10644411, ZFA:0001315]
synonym: "AV canal" EXACT []
xref: UBERON:0002087
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: xenbase3
creation_date: 2011-08-25T11:16:48Z

[Term]
id: XAO:0004124
name: atrioventricular canal endocardium
namespace: xenopus_anatomy
def: "Endocardium that is part of the atrioventricular canal." [PMID:10644411, ZFA:0001616]
xref: UBERON:0003930
is_a: XAO:0000066 ! endocardium
relationship: part_of XAO:0004123 ! atrioventricular canal
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: xenbase3
creation_date: 2011-08-25T11:19:42Z

[Term]
id: XAO:0004125
name: atrioventricular valve leaflet
namespace: xenopus_anatomy
def: "A portion of tissue forming a cusp guarding the opening of the atrioventricular valve." [XAO:EJS]
synonym: "atrioventricular valve leaflets" RELATED PLURAL []
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: xenbase3
creation_date: 2011-08-25T11:20:57Z

[Term]
id: XAO:0004126
name: cardiac valve
namespace: xenopus_anatomy
def: "Portion of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles." [UBERON:0000946]
synonym: "heart valve " RELATED []
xref: UBERON:0000946
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: xenbase3
creation_date: 2011-08-25T11:22:41Z

[Term]
id: XAO:0004127
name: m. geniohyoideus
namespace: xenopus_anatomy
alt_id: XAO:0004347
def: "Muscle that pulls the hyoid apparatus forward and depresses the lower jaw." [XAO:curators]
synonym: "geniohyoideus" EXACT []
synonym: "mgh" EXACT []
xref: UBERON:0011151
is_a: XAO:0004326 ! hypobranchial head muscle
relationship: develops_from XAO:0004444 ! m. geniohyoideus primordium
created_by: xenbase3
creation_date: 2011-08-25T11:33:42Z

[Term]
id: XAO:0004128
name: m. rectus abdominis
namespace: xenopus_anatomy
def: "Muscle of the abdomen that continues anteriorly as the m. rectus cervicis." [ISBN:080184780X, XAO:curators]
synonym: "rectus abdominis" EXACT []
xref: UBERON:0002382
is_a: XAO:0000172 ! muscle
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: xenbase3
creation_date: 2011-08-25T11:34:32Z

[Term]
id: XAO:0004129
name: m. rectus cervicus
namespace: xenopus_anatomy
alt_id: XAO:0004348
def: "Muscle that retracts the hyoid and, therefore, the tongue." [XAO:curators]
synonym: "mrc" EXACT []
synonym: "rectus cervicis" EXACT []
is_a: XAO:0004326 ! hypobranchial head muscle
relationship: develops_from XAO:0004445 ! m. rectus cervicis primordium
created_by: xenbase3
creation_date: 2011-08-25T11:34:53Z

[Term]
id: XAO:0004130
name: auditory hair cell
namespace: xenopus_anatomy
def: "A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system." [CL:0000202]
xref: CL:0000202
is_a: XAO:0004138 ! sensory epithelial cell
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-25T11:41:17Z

[Term]
id: XAO:0004131
name: lateral crista
namespace: xenopus_anatomy
def: "Horizontal (lateral) patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105]
synonym: "horizontal crista" EXACT []
is_a: XAO:0004138 ! sensory epithelial cell
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-25T11:44:54Z

[Term]
id: XAO:0004132
name: presumptive ectoderm
namespace: xenopus_anatomy
def: "Presumptive structure at the animal pole of the blastula that will develop into ectoderm." [UBERON:0006601]
xref: UBERON:0006601
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000019 ! NF stage 9
created_by: xenbase3
creation_date: 2011-08-26T08:59:00Z

[Term]
id: XAO:0004133
name: posterior crista
namespace: xenopus_anatomy
def: "Posterior patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105]
xref: UBERON:0007275
is_a: XAO:0004138 ! sensory epithelial cell
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-26T09:03:42Z

[Term]
id: XAO:0004134
name: presumptive paraxial mesoderm
namespace: xenopus_anatomy
def: "Presumptive structure that will develop into paraxial mesoderm." [XAO:curators]
xref: UBERON:0007285
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000050 ! mesoderm
relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000031 ! NF stage 10.5
created_by: xenbase3
creation_date: 2011-08-26T09:08:28Z

[Term]
id: XAO:0004135
name: rhombic lip
namespace: xenopus_anatomy
def: "The interface between the dorsal neuroepithelium and the roof plate of the fourth ventricle. The source of a number of migratory neuron populations of the hindbrain." [UBERON:0006215]
xref: UBERON:0006215
is_a: XAO:0003043 ! primordium
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000015 ! hindbrain
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-26T09:25:54Z

[Term]
id: XAO:0004136
name: saccular macula
namespace: xenopus_anatomy
def: "Portion of tissue that is a patch of thickened, pseudostratified epithelium in the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. The macula saccule senses linear acceleration and gravity." [PMID:20201105]
xref: UBERON:0002212
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-26T09:31:03Z

[Term]
id: XAO:0004137
name: anterior crista
namespace: xenopus_anatomy
def: "Anterior patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105]
synonym: "anterior cristae" RELATED PLURAL []
xref: UBERON:0007274
is_a: XAO:0004138 ! sensory epithelial cell
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-26T09:42:59Z

[Term]
id: XAO:0004138
name: sensory epithelial cell
namespace: xenopus_anatomy
def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibuloauditory systems; they contain sensory cells surrounded by supportive, non-receptive cells." [CL:0000098]
xref: CL:0000098
is_a: XAO:0003249 ! epithelial cell
relationship: start_stage XAO:1000037 ! NF stage 21
created_by: xenbase3
creation_date: 2011-08-26T09:52:26Z

[Term]
id: XAO:0004139
name: outflow tract
namespace: xenopus_anatomy
def: "The portion of the heart through which blood flows into the pulmocutaneous and systemic arteries. It is derived from cardiac precusor cells of the secondary heart field, and septation is incomplete." [PMID:10644411, PMID:20671188, UBERON:0004145]
xref: UBERON:0004145
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0004190 ! cardiac neural crest
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: xenbase3
creation_date: 2011-08-26T10:12:24Z

[Term]
id: XAO:0004140
name: ventricular outflow tract
namespace: xenopus_anatomy
def: "A portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle." [PMID:10644411, UBERON:0005337]
xref: UBERON:0005337
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004139 ! outflow tract
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: xenbase3
creation_date: 2011-08-26T10:17:59Z

[Term]
id: XAO:0004141
name: spiral septum
namespace: xenopus_anatomy
def: "The thin, spiral-shaped membranous structure within the ventricular outflow tract of the heart." [PMID:10644411]
synonym: "spiral septa" RELATED PLURAL []
xref: UBERON:0002099
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0004186 ! secondary heart field
relationship: part_of XAO:0004140 ! ventricular outflow tract
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: xenbase3
creation_date: 2011-08-26T10:22:27Z

[Term]
id: XAO:0004142
name: vestibulocochlear ganglion
namespace: xenopus_anatomy
def: "Ganglion that provides afferent innervation for hair cells associated with both the auditory and vestibular components of the inner ear. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII." [PMID:21452441]
synonym: "statoacoustic (VIII) ganglion" EXACT []
synonym: "statoacoustic ganglion" EXACT []
synonym: "vestibulocochlear ganglia" RELATED PLURAL []
synonym: "vestibulocochlear VIII ganglion" EXACT []
xref: UBERON:0002827
is_a: XAO:0000209 ! ganglion
relationship: develops_from XAO:0000223 ! otic placode
relationship: part_of XAO:0003095 ! vestibulocochlear nerve
created_by: xenbase3
creation_date: 2011-08-26T10:41:25Z

[Term]
id: XAO:0004143
name: vascular plexus
namespace: xenopus_anatomy
def: "Any network of intercommunicating blood vessels." [XAO:curators]
xref: UBERON:0005629
is_a: XAO:0001011 ! blood vessel
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: xenbase3
creation_date: 2011-08-26T10:59:34Z

[Term]
id: XAO:0004144
name: anterior ventral blood island
namespace: xenopus_anatomy
def: "Region that is overlapping, anterior, and dorsal to the main body of the ventral blood island." [PMID:21069823]
synonym: "aVBI" EXACT []
synonym: "blood island" BROAD []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0004473 ! ventral mesoderm
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: part_of XAO:0000067 ! ventral blood island
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: xenbase3
creation_date: 2011-08-26T11:20:29Z

[Term]
id: XAO:0004145
name: vestibular apparatus
namespace: xenopus_anatomy
def: "A small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear." [UBERON:0005236]
xref: UBERON:0001862
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: xenbase3
creation_date: 2011-08-26T11:46:49Z

[Term]
id: XAO:0004146
name: hemangioblast
namespace: xenopus_anatomy
def: "A pluripotent cell in the ventral blood island that can give rise to mesenchymal cells including erythrocytes and endothelial cells." [PMID:11495698]
xref: CL:0002418
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: lab
creation_date: 2011-08-30T10:27:52Z

[Term]
id: XAO:0004147
name: vitelline vein
namespace: xenopus_anatomy
def: "One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids." [UBERON:0005487]
synonym: "vascular vitelline network" EXACT []
synonym: "vitelline veins" RELATED PLURAL []
xref: UBERON:0005487
is_a: XAO:0000115 ! vein
relationship: develops_from XAO:0004144 ! anterior ventral blood island
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-08-30T10:36:35Z

[Term]
id: XAO:0004148
name: myeloid cell
namespace: xenopus_anatomy
def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763]
xref: CL:0000763
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0004144 ! anterior ventral blood island
relationship: develops_from XAO:0004628 ! posterior ventral blood island
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: lab
creation_date: 2011-08-30T10:44:28Z

[Term]
id: XAO:0004149
name: endothelial cell
namespace: xenopus_anatomy
def: "Cell that comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115]
xref: CL:0000115
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000356 ! vascular endothelium
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: lab
creation_date: 2011-08-30T10:48:16Z

[Term]
id: XAO:0004150
name: erythroid cell
namespace: xenopus_anatomy
def: "An immature or mature cell in the lineage leading to and including erythrocytes." [CL:0000764]
synonym: "erythroid lineage cell" RELATED []
xref: CL:0000764
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0004144 ! anterior ventral blood island
relationship: develops_from XAO:0004628 ! posterior ventral blood island
relationship: part_of XAO:0000122 ! hematological system
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: lab
creation_date: 2011-08-30T10:53:48Z

[Term]
id: XAO:0004151
name: tail vasculature
namespace: xenopus_anatomy
def: "Posterior vascular precursor cells of the tail region." [PMID:21069823]
xref: UBERON:0010204
is_a: XAO:0001011 ! blood vessel
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003026 ! tail
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-08-30T11:01:48Z

[Term]
id: XAO:0004152
name: head vasculature
namespace: xenopus_anatomy
def: "The blood vessels of the head region." [PMID:21069823]
xref: UBERON:0002200
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: lab
creation_date: 2011-08-30T11:05:38Z

[Term]
id: XAO:0004153
name: retinal blood vessel
namespace: xenopus_anatomy
def: "Blood vessels of the retina. May be visible in periocular stainings." [XAO:curators]
synonym: "retinal blood vessels" RELATED PLURAL []
xref: UBERON:0004864
is_a: XAO:0001011 ! blood vessel
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: lab
creation_date: 2011-08-30T11:39:54Z

[Term]
id: XAO:0004154
name: hyaloid blood vessel
namespace: xenopus_anatomy
def: "Vessels that are associated with the posterior region of the lens." [XAO:EJS, ZFA:0005046]
synonym: "hyaloid blood vessels" EXACT PLURAL []
synonym: "hyaloid vessel" EXACT []
synonym: "hyaloid vessels" EXACT PLURAL []
xref: UBERON:0005492
is_a: XAO:0001011 ! blood vessel
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: lab
creation_date: 2011-08-30T11:43:24Z

[Term]
id: XAO:0004155
name: hyaloid artery
namespace: xenopus_anatomy
def: "The hyaloid artery is a branch of the ophthalmic artery, which is itself a branch of the internal carotid artery. It is contained within the optic stalk of the eye and extends from the optic disc through the vitreous humor to the lens. Its purpose is to supply nutrient to the developing lens." [UBERON:0002270]
xref: UBERON:0002270
is_a: XAO:0004154 ! hyaloid blood vessel
created_by: lab
creation_date: 2011-08-30T11:47:17Z

[Term]
id: XAO:0004156
name: hyaloid vein
namespace: xenopus_anatomy
def: "Vein internal to the eye." [UBERON:006011]
xref: UBERON:0006011
is_a: XAO:0004154 ! hyaloid blood vessel
created_by: lab
creation_date: 2011-08-30T11:51:28Z

[Term]
id: XAO:0004157
name: hyaloid vascular plexus
namespace: xenopus_anatomy
def: "Network of intersecting blood vessels associated with the posterior region of the lens." [XAO:EJS]
xref: UBERON:0005607
is_a: XAO:0004154 ! hyaloid blood vessel
created_by: lab
creation_date: 2011-08-30T11:53:20Z

[Term]
id: XAO:0004158
name: anterior cerebral vein
namespace: xenopus_anatomy
def: "Vein that crosses the head dorsally at NF stage 37/38 and drains into the vena capitis medialis." [PMID:12606281]
xref: UBERON:0001672
is_a: XAO:0004160 ! cerebral vein
created_by: lab
creation_date: 2011-08-30T12:00:30Z

[Term]
id: XAO:0004159
name: posterior cerebral vein
namespace: xenopus_anatomy
def: "Vein that drains the dorsal longitudinal vessel and the caudal portions of the venous capillary network of the medulla oblongata. The cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis." [PMID:12606281, ZFA:0005027]
is_a: XAO:0004160 ! cerebral vein
relationship: end_stage XAO:1000059 ! NF stage 47
created_by: lab
creation_date: 2011-08-30T12:13:01Z

[Term]
id: XAO:0004160
name: cerebral vein
namespace: xenopus_anatomy
def: "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The veins are the anterior cerebral veins, posterior cerebral veins, and middle cerebral vein which cross dorsally between the bilateral vena capitis lateralis." [UBERON:001663]
xref: UBERON:0001663
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-08-30T12:16:59Z

[Term]
id: XAO:0004161
name: middle cerebral vein
namespace: xenopus_anatomy
def: "Type of vein that crosses the head dorsally at NF stage 37/38 and drains into the vena capitis lateralis." [PMID:12606281]
synonym: "mid cerebral vein" EXACT []
synonym: "mid-cerebral vein" EXACT []
is_a: XAO:0004160 ! cerebral vein
created_by: lab
creation_date: 2011-08-30T12:23:07Z

[Term]
id: XAO:0004162
name: pulmonary artery
namespace: xenopus_anatomy
def: "Type of artery that carries blood from the heart to the lungs. They are the only arteries that carry deoxygenated blood. Develops from aortic arch 6." [UBERON:0002012]
xref: UBERON:0002012
is_a: XAO:0000114 ! artery
relationship: develops_from XAO:0000353 ! aortic arch 6
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: lab
creation_date: 2011-08-30T01:59:48Z

[Term]
id: XAO:0004163
name: angioblast
namespace: xenopus_anatomy
def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [CL:0000566]
synonym: "angioblasts" EXACT PLURAL []
xref: CL:0000566
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: lab
creation_date: 2011-08-30T02:11:31Z

[Term]
id: XAO:0004164
name: intersomitic vein
namespace: xenopus_anatomy
def: "Type of vein that sprouts from the posterior cardinal vein, growing dorsally between the somites, and then joining, and draining the dorsal longitudinal anastomosing vessel." [PMID:12606281]
is_a: XAO:0004075 ! intersomitic vessel
relationship: develops_from XAO:0000241 ! posterior cardinal vein
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-08-30T02:26:59Z

[Term]
id: XAO:0004165
name: intersomitic artery
namespace: xenopus_anatomy
def: "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." [PMID:12606281]
xref: UBERON:0006001
is_a: XAO:0004075 ! intersomitic vessel
relationship: develops_from XAO:0000051 ! dorsal aorta
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-08-30T02:29:23Z

[Term]
id: XAO:0004166
name: left omphalomesenteric vein
namespace: xenopus_anatomy
def: "In the trunk region, one of the veins into which the subintestinal vein drains, and which breaks up to merge with the vitelline network at NF stage 40." [PMID:12606281]
is_a: XAO:0000376 ! omphalomesenteric vein
relationship: end_stage XAO:1000052 ! NF stage 40
created_by: lab
creation_date: 2011-08-31T10:32:04Z

[Term]
id: XAO:0004167
name: metencephalic artery
namespace: xenopus_anatomy
def: "The artery that crosses the brain dorsally, and meets the metencephalic vein." [PMID:12606281]
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0000010 ! brain
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-08-31T10:38:54Z

[Term]
id: XAO:0004168
name: metencephalic vein
namespace: xenopus_anatomy
def: "The vein that crosses the brain dorsally, parallel with the mid-cerebral vein, and meets the metencephalic artery." [PMID:12606281]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0000010 ! brain
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-08-31T10:43:06Z

[Term]
id: XAO:0004169
name: ophthalmic vein
namespace: xenopus_anatomy
def: "The dorsal branch/remnant of the vena capitis medialis, that drains blood from the eye. Together with the opthalmic artery, form a double ring encircling the eye and retina." [PMID:12606281]
xref: UBERON:0011191
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004170 ! vena capitis medialis
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: lab
creation_date: 2011-08-31T11:03:57Z

[Term]
id: XAO:0004170
name: vena capitis medialis
namespace: xenopus_anatomy
def: "One of the major dorsal head veins that drains into the anterior cardinal vein, the other being the vena capitis lateralis." [PMID:12606281]
synonym: "VCM" EXACT []
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-08-31T11:14:19Z

[Term]
id: XAO:0004171
name: vena capitis lateralis
namespace: xenopus_anatomy
def: "One of the major dorsal head veins that drains into the anterior cardinal vein, the other being the vena capitis medialis." [PMID:12606281]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-08-31T11:22:11Z

[Term]
id: XAO:0004172
name: subintestinal vein
namespace: xenopus_anatomy
def: "Vein that is formed from and drains into the left omphalomesentric vein, and by NF stage 40, it is on the left side of the gut. It moves to the most ventral aspect of the gut during stage 41, and is on the right side of the gut by stage 43." [PMID:12606281]
xref: UBERON:0011944
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004151 ! tail vasculature
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: lab
creation_date: 2011-08-31T11:24:56Z

[Term]
id: XAO:0004173
name: mesencephalic artery
namespace: xenopus_anatomy
def: "The major artery of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic vein." [PMID:12606281]
xref: UBERON:0001634
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0000014 ! midbrain
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: lab
creation_date: 2011-08-31T12:02:13Z

[Term]
id: XAO:0004174
name: mesencephalic vein
namespace: xenopus_anatomy
def: "The major vein of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic artery." [PMID:12606281]
xref: UBERON:0010205
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0000014 ! midbrain
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: lab
creation_date: 2011-08-31T12:04:02Z

[Term]
id: XAO:0004175
name: nasociliary artery
namespace: xenopus_anatomy
def: "The main artery of the olfactory region which arises from the cerebral artery at NF stage 41." [PMID:12606281]
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: lab
creation_date: 2011-08-31T12:13:11Z

[Term]
id: XAO:0004176
name: optic choroid vascular plexus
namespace: xenopus_anatomy
def: "A plexus of capillaries that is located anteromedial to the eye. It is a capillary layer in the choroid. It is in contact with the basal surface of the retinal pigmented epithelium and supplies the photoreceptors with oxygen and nutrients. The fused basement membrane of this capillary layer and the pigmented epithelium is called Bruch's membrane." [ISBN:1402073755]
synonym: "capillary lamina of choroid" EXACT []
synonym: "choriocapillaris" EXACT []
synonym: "choroidal vascular plexus" EXACT []
xref: UBERON:0010078
is_a: XAO:0004143 ! vascular plexus
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000056 ! NF stage 44
created_by: lab
creation_date: 2011-08-31T12:26:08Z

[Term]
id: XAO:0004177
name: dorsal longitudinal anastomosing vessel
namespace: xenopus_anatomy
def: "Vessel into which intersomitic vessels enter in a regular pattern at each intersomitic junction. Posterior to the gut, the DLAV drains into the fused posterior cardinal vein by a minor right branch and a major left branch. By NF stage 36 the DLAV extends fully to the tip of the tail." [PMID:12606281]
synonym: "DLAV" EXACT []
is_a: XAO:0001011 ! blood vessel
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-08-31T01:27:30Z

[Term]
id: XAO:0004178
name: dorsal longitudinal anastomosing vessel - left branch
namespace: xenopus_anatomy
def: "The major (left) branch of the dorsal longitudinal anastomosing vessel (dlav); it remains as the sole branch after the right branch breaks up at NF stage 44." [PMID:12606281]
synonym: "DLAV - left branch" RELATED []
is_a: XAO:0004177 ! dorsal longitudinal anastomosing vessel
created_by: lab
creation_date: 2011-08-31T01:33:06Z

[Term]
id: XAO:0004179
name: dorsal longitudinal anastomosing vessel - right branch
namespace: xenopus_anatomy
def: "The minor (right) branch of the dorsal longitudinal anastomosing vessel (dlav); the right branch disappears during NF stage 44." [PMID:12606281]
synonym: "DLAV - right branch" EXACT []
is_a: XAO:0004177 ! dorsal longitudinal anastomosing vessel
relationship: end_stage XAO:1000057 ! NF stage 45
created_by: lab
creation_date: 2011-08-31T01:38:24Z

[Term]
id: XAO:0004180
name: olfactory bulb
namespace: xenopus_anatomy
def: "Part of the telencephalon, comprising paired anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits. The olfactory bulbs begin to fuse at NF stage 50, and fusion is complete around NF stage 58. The cerebral vein loops around the olfactory bulb by NF stage 43." [AAO:0010165, ISBN:0815318960]
synonym: "bulbus olfactorius" EXACT []
synonym: "OB" EXACT []
synonym: "olfactory lobe" RELATED []
xref: UBERON:0002264
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000012 ! telencephalon
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: lab
creation_date: 2011-08-31T02:08:00Z

[Term]
id: XAO:0004181
name: cardiac myocyte
namespace: xenopus_anatomy
def: "Type of myocyte that is responsible for heart contraction." [CL:0000746]
synonym: "cardiac muscle cell" RELATED []
synonym: "cardiac muscle cells" RELATED PLURAL []
synonym: "cardiac myocytes" RELATED PLURAL []
synonym: "cardiomyocyte" RELATED []
synonym: "cardiomyocytes" RELATED PLURAL []
xref: CL:0000746
is_a: XAO:0004475 ! myocyte
relationship: part_of XAO:0000065 ! myocardium
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: lab
creation_date: 2011-09-02T09:18:06Z

[Term]
id: XAO:0004182
name: pericardium
namespace: xenopus_anatomy
def: "The outer membrane/wall of the developing heart, surrounding the myocardium. Peritoneum that surrounds the heart." [AAO:0010817]
xref: UBERON:0002407
is_a: XAO:0000139 ! peritoneum
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: lab
creation_date: 2011-09-02T09:40:58Z

[Term]
id: XAO:0004183
name: pericardial muscle
namespace: xenopus_anatomy
def: "Muscle that is paired and runs anterio-posteriorly along the heart and is covered with epicardium." [XAO:EJS, ZFA:0001653]
is_a: XAO:0000172 ! muscle
relationship: part_of XAO:0000064 ! heart
created_by: lab
creation_date: 2011-09-02T09:46:21Z

[Term]
id: XAO:0004184
name: pericardial roof
namespace: xenopus_anatomy
def: "The dorsal region of the pericardium." [PMID:18598690]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004182 ! pericardium
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: lab
creation_date: 2011-09-02T10:01:41Z

[Term]
id: XAO:0004185
name: primary heart field
namespace: xenopus_anatomy
def: "The field of cardiac progenitor cells that form the heart tube in the embryonic heart." [PMID:18598690, PMID:20671188]
synonym: "FHF" RELATED []
synonym: "first heart field" EXACT []
synonym: "PHF" RELATED []
xref: UBERON:0004140
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000235 ! cardiac mesoderm
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000035 ! NF stage 19
created_by: lab
creation_date: 2011-09-02T10:49:26Z

[Term]
id: XAO:0004186
name: secondary heart field
namespace: xenopus_anatomy
def: "The population of cells located in the splanchnic mesoderm that contribute to the formation of the spiral septum of the outflow tract of the embryonic heart; it is located anterior to the primary heart field." [PMID:18598690, PMID:20671188]
synonym: "second heart field" EXACT []
synonym: "SHF" RELATED []
xref: UBERON:0009889
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000041 ! NF stage 25
created_by: lab
creation_date: 2011-09-02T10:56:21Z

[Term]
id: XAO:0004187
name: anterior branchial crest
namespace: xenopus_anatomy
def: "Branchial crest that is the 3rd neural crest stream and lays between hyoid crest and posterior branchial crest." [PMID:21490068]
synonym: "ABC" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000026 ! branchial crest
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000026 ! branchial crest
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: lab
creation_date: 2011-09-02T11:14:48Z

[Term]
id: XAO:0004188
name: posterior branchial crest
namespace: xenopus_anatomy
def: "Branchial crest that is the most posterior of the five neural crest streams." [PMID:21490068]
synonym: "PBC" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000026 ! branchial crest
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000026 ! branchial crest
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: lab
creation_date: 2011-09-02T11:18:11Z

[Term]
id: XAO:0004189
name: endocardial cushion
namespace: xenopus_anatomy
def: "The discrete swellings of cardiac jelly in the outflow tract and ventricular walls of the developing embryonic heart." [PMID:21490068]
synonym: "cardiac cushion" RELATED []
xref: UBERON:0002062
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000048 ! NF stage 33 and 34
relationship: part_of XAO:0000066 ! endocardium
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: lab
creation_date: 2011-09-02T02:17:35Z

[Term]
id: XAO:0004190
name: cardiac neural crest
namespace: xenopus_anatomy
def: "Neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to contribute to the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart where it contributes to connective tissue (septa) that separates the vessels of the heart. Cardiac neural crest develops into melanocytes, cartilage, connective tissue and neurons of some pharyngeal arches." [http://en.wikipedia.org/wiki/Cardiac_neural_crest_complex]
xref: UBERON:0000095
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: lab
creation_date: 2011-09-02T02:35:20Z

[Term]
id: XAO:0004191
name: vagal neural crest
namespace: xenopus_anatomy
def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the sacral neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. These cells, between the head and trunk, contribute post-cranially to the heart and gut, the chromatophores (pigment cells) of the epidermis, and the majority of the neurons and glial cells of the enteric nervous system. Both vagal and sacral neural crest cells contribute to the enteric nervous system in the hindgut." [PMID:9753687, XAO:CJZ]
synonym: "VNC" EXACT []
xref: UBERON:0005428
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: lab
creation_date: 2011-09-02T02:50:42Z

[Term]
id: XAO:0004192
name: sacral neural crest
namespace: xenopus_anatomy
def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the vagal neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. Sacral crest cells are associated with extrinsic nerve fibers of the hindgut and colon." [XAO:CJZ]
synonym: "SNC" EXACT []
xref: UBERON:0010075
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: lab
creation_date: 2011-09-02T02:53:34Z

[Term]
id: XAO:0004193
name: ossicle
namespace: xenopus_anatomy
def: "Skeletal element that is often isolated, small, and variable in composition." [UBERON:0010911]
xref: UBERON:0010911
is_a: XAO:0004012 ! skeletal element
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: lab
creation_date: 2011-09-13T09:36:09Z

[Term]
id: XAO:0004194
name: appendicular ossicle
namespace: xenopus_anatomy
def: "Ossicle that is part of the appendicular skeleton." [UBERON:0011141]
xref: UBERON:0011141
is_a: XAO:0004193 ! ossicle
relationship: part_of XAO:0003166 ! appendicular skeleton
created_by: lab
creation_date: 2011-09-13T09:38:19Z

[Term]
id: XAO:0004195
name: cellular bone tissue
namespace: xenopus_anatomy
def: "Mineralized bone tissue that always includes non-terminally differentiated osteoblasts and osteocytes." [UBERON:4000118]
xref: UBERON:4000118
is_a: XAO:0004040 ! mineralized bone tissue
created_by: lab
creation_date: 2011-09-13T09:43:56Z

[Term]
id: XAO:0004196
name: cementum
namespace: xenopus_anatomy
def: "Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument." [UBERON:0001753]
synonym: "bone of attachment" RELATED []
xref: UBERON:0001753
is_a: XAO:0004046 ! odontoid tissue
created_by: lab
creation_date: 2011-09-13T09:46:43Z

[Term]
id: XAO:0004197
name: elastic cartilage tissue
namespace: xenopus_anatomy
def: "Cartilage tissue that is flexible and contains abundant elastic fibers." [UBERON:0001996]
synonym: "elastic cartilage" EXACT []
xref: UBERON:0001996
is_a: XAO:0004044 ! non-mineralized hyaline cartilage tissue
relationship: develops_from XAO:0004022 ! cartilaginous condensation
created_by: lab
creation_date: 2011-09-13T09:48:42Z

[Term]
id: XAO:0004198
name: enamel
namespace: xenopus_anatomy
def: "Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. It develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix." [VSAO:0000065]
synonym: "enamel tissue" EXACT []
synonym: "tooth enamel" EXACT []
xref: UBERON:0001752
is_a: XAO:0004046 ! odontoid tissue
relationship: develops_from XAO:0004202 ! pre-enamel
created_by: lab
creation_date: 2011-09-13T09:51:23Z

[Term]
id: XAO:0004199
name: enameloid
namespace: xenopus_anatomy
def: "Skeletal tissue that is hypermineralized and aprismatic and deposited by a combination of ameloblasts and odontoblasts that are excluded from the matrix. It develops from pre-enameloid tissue." [UBERON:0011692]
synonym: "bitypic enamel" EXACT []
synonym: "durodentine" EXACT []
synonym: "enameloid tissue" EXACT []
synonym: "vitrodentine" EXACT []
xref: UBERON:0011692
is_a: XAO:0004046 ! odontoid tissue
relationship: develops_from XAO:0004203 ! pre-enameloid
created_by: lab
creation_date: 2011-09-13T09:56:25Z

[Term]
id: XAO:0004200
name: non-mineralized chondroid tissue
namespace: xenopus_anatomy
def: "Chondroid tissue that is not mineralized." [XAO:EJS]
is_a: XAO:0004038 ! skeletal tissue
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: lab
creation_date: 2011-09-13T09:59:02Z

[Term]
id: XAO:0004201
name: odontode tissue
namespace: xenopus_anatomy
def: "Skeletal tissue that is avascular tubular mineralized matrix, primarily made of dentine that is deposited by odontoblasts that are excluded from the matrix; develops from pre-dentine tissue." [VSAO:0000123]
synonym: "dental tissue" RELATED []
is_a: XAO:0004046 ! odontoid tissue
relationship: develops_from XAO:0004052 ! pre-dentine
created_by: lab
creation_date: 2011-09-13T10:00:35Z

[Term]
id: XAO:0004202
name: pre-enamel
namespace: xenopus_anatomy
def: "Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix." [UBERON:0011588]
synonym: "pre-enamel tissue" EXACT []
synonym: "preenamel tissue" EXACT []
xref: UBERON:0011588
is_a: XAO:0004046 ! odontoid tissue
created_by: lab
creation_date: 2011-09-13T10:08:54Z

[Term]
id: XAO:0004203
name: pre-enameloid
namespace: xenopus_anatomy
def: "Odontoid tissue that is avascular non-mineralized matrix that is deposited by odontoblasts and ameloblasts that are excluded from the matrix." [UBERON:0011688]
synonym: "non-mineralized enameloid tissue" EXACT []
xref: UBERON:0011688
is_a: XAO:0004046 ! odontoid tissue
created_by: lab
creation_date: 2011-09-13T10:15:16Z

[Term]
id: XAO:0004204
name: sesamoid
namespace: xenopus_anatomy
def: "Replacement element; an ossicle; often an endochondral replacement element that has cartilage and bone states that develops in dense regular connective tissue (e.g., tendons and ligaments)." [VSAO:0000137]
xref: UBERON:0013631
is_a: XAO:0004193 ! ossicle
relationship: start_stage XAO:1000074 ! NF stage 62
created_by: lab
creation_date: 2011-09-13T10:23:39Z

[Term]
id: XAO:0004205
name: gall bladder primordium
namespace: xenopus_anatomy
def: "A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops." [ISBN:0815318960]
xref: UBERON:0006242
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0004513 ! foregut endoderm
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: lab
creation_date: 2011-09-13T01:15:58Z

[Term]
id: XAO:0004206
name: anterior placodal area
namespace: xenopus_anatomy
def: "One of the 3 domains of the U-shaped preplacodal ectoderm (PPE), which lies abutting and anterior to the neural plate." [ISBN:0878933840]
synonym: "anterior preplacodal ectoderm" RELATED []
synonym: "APA" EXACT []
synonym: "APPE" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: part_of XAO:0004092 ! preplacodal ectoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5
created_by: lab
creation_date: 2011-09-13T01:29:48Z

[Term]
id: XAO:0004207
name: posterior placodal area
namespace: xenopus_anatomy
def: "One of the 3 domains of the U-shaped preplacodal ectoderm (PPE), which lies abutting and lateral to the chordal neural plate border and neural crest." [ISBN:0878933840]
synonym: "posterior preplacodal ectoderm" RELATED []
synonym: "PPA" EXACT []
synonym: "PPPE" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0004092 ! preplacodal ectoderm
relationship: start_stage XAO:1000032 ! NF stage 11.5
created_by: lab
creation_date: 2011-09-13T01:40:58Z

[Term]
id: XAO:0004208
name: adenohypophyseal placode
namespace: xenopus_anatomy
def: "The small pre-placodal ectoderm area that develops at the midline of the anterior neural ridge, abutting the anterior neural plate, and invaginates to form Rathke's pouch, which in turn forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary." [ISBN:0878933840]
synonym: "pituitary placode" EXACT []
xref: UBERON:0009122
is_a: XAO:0004620 ! neurogenic placode
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0004091 ! non-neural ectoderm
relationship: start_stage XAO:1000027 ! NF stage 17
created_by: lab
creation_date: 2011-09-13T01:47:17Z

[Term]
id: XAO:0004209
name: anterior neural ridge
namespace: xenopus_anatomy
def: "The region that delineates the rostral boundary of the neural plate in the neural stage embryo, and is devoid of neural crest cells. It gives rise to the pre-placodal region, some elements of the forebrain, and the anterior lobe of the pituitary gland." [ISBN:0878933840]
synonym: "ANR" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000042 ! neuroectoderm
relationship: end_stage XAO:1000038 ! NF stage 22
relationship: part_of XAO:0000249 ! neural plate
relationship: start_stage XAO:1000032 ! NF stage 11.5
created_by: lab
creation_date: 2011-09-13T02:26:18Z

[Term]
id: XAO:0004210
name: infundibulum
namespace: xenopus_anatomy
def: "The region of the diencephalon above Rathke's pouch, and forms the posterior lobe of the pituitary." [XAO:curators]
synonym: "hypophysial stalk" EXACT []
synonym: "infundibulum of hypothalamus" EXACT []
synonym: "pituitary stalk" EXACT []
xref: UBERON:0002434
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: lab
creation_date: 2011-09-13T02:33:45Z

[Term]
id: XAO:0004211
name: facial epibranchial placode
namespace: xenopus_anatomy
def: "The most anterior of the epibranchial placodes, associated with the 1st pharyngeal cleft and contributing to the distal ganglia of cranial nerve VII (facial nerve)." [ISBN:0878933840]
synonym: "epVII" EXACT []
synonym: "geniculate placode" EXACT []
xref: UBERON:0009124
is_a: XAO:0000284 ! epibranchial placode
created_by: lab
creation_date: 2011-09-14T09:21:23Z

[Term]
id: XAO:0004212
name: glossopharyngeal epibranchial placode
namespace: xenopus_anatomy
def: "The central of the three epibranchial placodes, associated with the 2nd pharyngeal cleft and contributing to the distal ganglia of cranial nerve IX (glossopharyngeal nerve)." [ISBN:0878933840]
synonym: "epIX" EXACT []
synonym: "petrosal placode" EXACT []
xref: UBERON:0009125
is_a: XAO:0000284 ! epibranchial placode
created_by: lab
creation_date: 2011-09-14T09:25:28Z

[Term]
id: XAO:0004213
name: vagal epibranchial placode
namespace: xenopus_anatomy
def: "The most posterior of the epibranchial placodes, in 3 distinct zones, associated with the 3rd to 6th pharyngeal clefts, and contributing to the facial, lateral line and glossopharyngeal ganglion." [ISBN:0878933840]
synonym: "nodose placode" EXACT []
synonym: "nodose placodes" EXACT PLURAL []
synonym: "vagal epibranchial placodes" EXACT PLURAL []
xref: UBERON:0009126
is_a: XAO:0000284 ! epibranchial placode
created_by: lab
creation_date: 2011-09-14T09:36:07Z

[Term]
id: XAO:0004214
name: accessory nerve
namespace: xenopus_anatomy
def: "Small motor nerve that emerges from the lateral wall of the medulla with the roots of the vagus nerve, and innervates a single pectoral suspensory muscle, the m. cucullaris." [ISBN:080184780X]
synonym: "accessorius" EXACT []
synonym: "cranial nerve XI" EXACT []
xref: UBERON:0002019
is_a: XAO:0000429 ! cranial nerve
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-09-14T10:03:25Z

[Term]
id: XAO:0004215
name: hypoglossal nerve
namespace: xenopus_anatomy
def: "Nerve that leads to the muscles of the tongue (mm geniohyoideus, genioglossus, hyoglossus, and rectus cervicis) and has both sensory and motor functions." [ISBN:080184780X]
comment: Duellman and Trueb (pg. 395) note that although the primordia of this nerve are in the 1st and 2nd spinal nerves, this nerve contains fibers representing the hypoglossal nerve in amniotes and is thus considered one of the cranial nerves.
synonym: "cranial nerve XII" EXACT []
synonym: "hypoglossus" EXACT []
xref: UBERON:0001650
is_a: XAO:0000429 ! cranial nerve
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: lab
creation_date: 2011-09-14T10:07:12Z

[Term]
id: XAO:0004216
name: glomeral nexus
namespace: xenopus_anatomy
def: "The narrow bridge that links the two glomera of the pronephric kidney." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000318 ! glomus
relationship: end_stage XAO:1000066 ! NF stage 54
relationship: part_of XAO:0000318 ! glomus
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: lab
creation_date: 2011-09-14T10:38:02Z

[Term]
id: XAO:0004217
name: motor neuron
namespace: xenopus_anatomy
def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100]
synonym: "motoneuron" EXACT []
xref: CL:0000100
is_a: XAO:0003023 ! neuron
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-01-27T09:25:00Z

[Term]
id: XAO:0004218
name: palatoquadrate
namespace: xenopus_anatomy
def: "The dorsal component of the mandibular arch, the ventral one being Meckel's cartilage. Together with the ceratohyal and connecting musculature, it is responsible for the ventilation and irrigation of the filter apparatus." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000024 ! mandibular crest
relationship: part_of XAO:0000097 ! mandibular arch
relationship: start_stage XAO:1000040 ! NF stage 24
created_by: eriksegerdell

[Term]
id: XAO:0004219
name: ceratohyal
namespace: xenopus_anatomy
def: "Cartilaginous element that, together with the palatoquadrate and connecting musculature, is responsible for the ventilation and irrigation of the of the filter apparatus." [XAO:curators]
synonym: "ch" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0000025 ! hyoid crest
relationship: part_of XAO:0000098 ! hyoid arch
created_by: eriksegerdell

[Term]
id: XAO:0004220
name: anteroventral lateral line placode
namespace: xenopus_anatomy
def: "Lateral line placode that gives rise to the anteroventral lateral line nerve." [XAO:EJS]
synonym: "anterior ventral lateral line placode" EXACT []
synonym: "pAV" EXACT []
is_a: XAO:0000440 ! lateral line placode
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell
creation_date: 2012-01-27T09:32:47Z

[Term]
id: XAO:0004221
name: anterior lateral line placode
namespace: xenopus_anatomy
def: "Lateral line placode that gives rise to the anterior lateral line nerve." [XAO:EJS]
synonym: "pre-auditory lateral line placode" RELATED []
is_a: XAO:0000440 ! lateral line placode
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell

[Term]
id: XAO:0004222
name: middle lateral line placode
namespace: xenopus_anatomy
def: "Lateral line placode that gives rise to the middle lateral line nerve." [XAO:EJS]
synonym: "intermediate lateral line placode" RELATED []
is_a: XAO:0000440 ! lateral line placode
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell

[Term]
id: XAO:0004223
name: posterior lateral line placode
namespace: xenopus_anatomy
def: "Lateral line placode that gives rise to the posterior lateral line nerve." [XAO:EJS]
synonym: "pP" EXACT []
synonym: "vagus lateral line placode" RELATED []
is_a: XAO:0000440 ! lateral line placode
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell

[Term]
id: XAO:0004224
name: transporting epithelium
namespace: xenopus_anatomy
def: "Type of epithelium that facilitates the transcellular transport of solutes. This transport can either be absorption, transport from lumen (apical membrane surface) to blood; or secretion, transport from blood (basolateral membrane surface) to lumen." [http://en.wikipedia.org/wiki/Transcellular_transport]
synonym: "transporting epithelia" RELATED PLURAL []
is_a: XAO:0003045 ! epithelium
created_by: eriksegerdell

[Term]
id: XAO:0004225
name: non-ciliated epithelial cell
namespace: xenopus_anatomy
def: "Type of cell of the epidermis lacking cilia, which separate and space the ciliated epidermal cells." [PMID:16728476]
synonym: "intercalating non-ciliated cell" RELATED []
synonym: "non-ciliated epithelial cells" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003249 ! epithelial cell
relationship: develops_from XAO:0000001 ! ectoderm
created_by: eriksegerdell

[Term]
id: XAO:0004226
name: ventral tegmentum
namespace: xenopus_anatomy
def: "Region of the mesencephalon that arises from a small area of the neural plate, spanning the midline immediately adjacent, and being slightly posterior to the dorsal tegmentum area." [PMID:2351962]
synonym: "tegmentum ventrale" EXACT []
synonym: "ventral brain stem" RELATED []
synonym: "ventral tegmental area" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000249 ! neural plate
relationship: part_of XAO:0004271 ! midbrain tegmentum
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: eriksegerdell

[Term]
id: XAO:0004227
name: dorsal tegmentum
namespace: xenopus_anatomy
def: "Region of the mesencephalon that arises from a small area of the neural plate immediately adjacent and slightly anterior to the ventral tegmentum area." [PMID:2351962]
synonym: "dorsal brain stem" RELATED []
synonym: "tegmentum dorsale" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000249 ! neural plate
relationship: part_of XAO:0004271 ! midbrain tegmentum
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: eriksegerdell

[Term]
id: XAO:0004228
name: lateral abdominal vein
namespace: xenopus_anatomy
def: "Laterally located vein that drains the ventral abdominal wall." [ISBN:0815318960]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-01-27T09:37:16Z

[Term]
id: XAO:0004229
name: fin crest
namespace: xenopus_anatomy
def: "The thin epidermis extension of the inner fin visible in the mid trunk region of the inner fin at NF stage 27, and extending posteriorly and then ventrally, ending just before the proctodeum. The fin is more homogeneous in NF stage 46 tadpoles, and the inner fin and fin crest are no longer discrete." [XAO:curators]
is_a: XAO:0003028 ! surface structure
relationship: develops_from XAO:0000004 ! inner fin
relationship: end_stage XAO:1000058 ! NF stage 46
relationship: part_of XAO:0000028 ! epidermis
relationship: part_of XAO:0003026 ! tail
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: eriksegerdell

[Term]
id: XAO:0004230
name: anterior hypothalamus
namespace: xenopus_anatomy
def: "Anterior part of the hypothalamus, given rise by the midanterior neural ridge along with the chiasmatic ridge during forebrain morphogenesis." [PMID:8537821]
synonym: "alar hypothalamus" EXACT []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004070 ! hypothalamus
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-01-27T09:51:09Z

[Term]
id: XAO:0004231
name: barbel
namespace: xenopus_anatomy
def: "A single long structure at each corner of the mouth that has muscle fibers attached to an internal cartilaginous support and that is mobile." [ISBN:0226557626]
is_a: XAO:0003028 ! surface structure
relationship: end_stage XAO:1000073 ! NF stage 61
relationship: start_stage XAO:1000056 ! NF stage 44
created_by: eriksegerdell

[Term]
id: XAO:0004232
name: spiracle
namespace: xenopus_anatomy
def: "The exit for respiratory water in the tadpole." [ISBN:0226557626]
is_a: XAO:0003028 ! surface structure
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell

[Term]
id: XAO:0004233
name: truncus arteriosus
namespace: xenopus_anatomy
def: "A cranial continuation of the bulbis cordis that contains two lateral branches and divides into the carotid arch, systemic arch, and pulmocutaneous arch." [ISBN:0801836018]
is_a: XAO:0001011 ! blood vessel
relationship: start_stage XAO:1000046 ! NF stage 31
created_by: eriksegerdell

[Term]
id: XAO:0004234
name: bulbous arteriosis
namespace: xenopus_anatomy
def: "Multi-tissue structure through which the blood exits the heart. It is a chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches." [XAO:EJS, ZFA:0000173]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell

[Term]
id: XAO:0004235
name: manicotto glandulare
namespace: xenopus_anatomy
def: "The larval stomach." [ISBN:0226893340]
is_a: XAO:0003037 ! multi-tissue structure
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000125 ! alimentary system
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell

[Term]
id: XAO:0004236
name: posterior hypothalamus
namespace: xenopus_anatomy
def: "Posterior part of the hypothalamus, given rise by the midanterior neural plate during forebrain morphogenesis." [PMID:8537821]
synonym: "basal hypothalamus" EXACT []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004070 ! hypothalamus
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-01-27T09:51:49Z

[Term]
id: XAO:0004237
name: lateral ganglionic eminence
namespace: xenopus_anatomy
def: "A distinct elevation of a transient proliferating cell mass of the subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE." [UBERON:0004025]
synonym: "LGE" RELATED []
xref: UBERON:0004025
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000064 ! NF stage 52
relationship: part_of XAO:0004258 ! subpallium
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-01-27T09:59:19Z

[Term]
id: XAO:0004238
name: femur rudiment
namespace: xenopus_anatomy
def: "A cartilaginous element that is the primordium or commencement of a femur." [XAO:EJS]
is_a: XAO:0004013 ! cartilage element
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: start_stage XAO:1000063 ! NF stage 51
created_by: eriksegerdell

[Term]
id: XAO:0004239
name: hindlimb digit 1
namespace: xenopus_anatomy
def: "The most posterior of the hind digits, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ]
synonym: "hallux" RELATED []
synonym: "hind digit 1" EXACT []
synonym: "pedal digit 1" EXACT []
synonym: "toe 1" EXACT []
synonym: "toe I" EXACT []
is_a: XAO:0003035 ! hindlimb digit
created_by: eriksegerdell

[Term]
id: XAO:0004240
name: branchial vein
namespace: xenopus_anatomy
def: "Type of vein that drains the gill region and which passes backwards lateral to the gill chambers and opens into the pronephric sinus." [ISBN:0815318960]
is_a: XAO:0000115 ! vein
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004241
name: ischiadic vein
namespace: xenopus_anatomy
def: "A vein of the hind limb, first visible in the developing hind limb bud at c. NF stage 50 when it enters the ventral commissural vessel." [ISBN:0815318960]
is_a: XAO:0000115 ! vein
relationship: start_stage XAO:1000062 ! NF stage 50
created_by: eriksegerdell

[Term]
id: XAO:0004242
name: ischiadic artery
namespace: xenopus_anatomy
def: "The accompanying artery of the ischiadic nerve." [http://en.wikipedia.org/wiki/Accompanying_artery_of_ischiadic_nerve]
is_a: XAO:0000114 ! artery
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004243
name: femoral vein
namespace: xenopus_anatomy
def: "Either of the primary veins in the hindlimbs that collect blood from the hindlimb region." [AAO:0010237]
synonym: "vena femoralis" RELATED []
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004296 ! hindlimb stylopod
relationship: start_stage XAO:1000063 ! NF stage 51
created_by: eriksegerdell

[Term]
id: XAO:0004244
name: mandibular artery
namespace: xenopus_anatomy
def: "Part of the lateral pretrosal artery that supplies blood to the roof of the mouth." [AAO:0010496]
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell

[Term]
id: XAO:0004245
name: maxillary artery
namespace: xenopus_anatomy
def: "A type of artery that supplies the deep structures of the facial region. It branches from the external carotid artery." [http://en.wikipedia.org/wiki/Maxillary_artery]
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell

[Term]
id: XAO:0004246
name: rhombomere R7
namespace: xenopus_anatomy
def: "The 7th segment of the developing hindbrain." [XAO:EJS]
synonym: "r7" EXACT []
synonym: "rhombomere 7" EXACT []
is_a: XAO:0004079 ! rhombomere
created_by: eriksegerdell
creation_date: 2012-01-27T10:01:06Z

[Term]
id: XAO:0004247
name: vertebral artery
namespace: xenopus_anatomy
def: "A major artery of the neck that branches from the subclavian arteries and merge to form the single midline basilar artery." [http://en.wikipedia.org/wiki/Vertebral_artery]
is_a: XAO:0000114 ! artery
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004248
name: epigastric artery
namespace: xenopus_anatomy
def: "Artery that supplies the anterior wall of the abdomen." [http://medical-dictionary.thefreedictionary.com/epigastric+artery]
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004249
name: renal artery
namespace: xenopus_anatomy
def: "Artery that supplies blood via branches to the gonads, oviducts, and kidneys." [AAO:0010223]
synonym: "interrenal artery" RELATED []
is_a: XAO:0000114 ! artery
relationship: part_of XAO:0000140 ! urogenital system
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004250
name: facial vein
namespace: xenopus_anatomy
def: "Vein that collects blood from muscles of the head and drains into the external jugular vein." [AAO:0010513]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004152 ! head vasculature
relationship: start_stage XAO:1000070 ! NF stage 58
created_by: eriksegerdell

[Term]
id: XAO:0004251
name: cutaneous magnus
namespace: xenopus_anatomy
def: "Vein that comes from the skin of the trunk." [XAO:EJS]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell

[Term]
id: XAO:0004252
name: cutaneous femoral vein
namespace: xenopus_anatomy
def: "Vein that comes from the subcutaneous tissue of the hindlimb stylopod." [XAO:EJS]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004296 ! hindlimb stylopod
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell

[Term]
id: XAO:0004253
name: postcaval vein
namespace: xenopus_anatomy
def: "One of three major veins that enter the sinus venosus." [AAO:0010506]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000060 ! NF stage 48
created_by: eriksegerdell

[Term]
id: XAO:0004254
name: subclavian vein
namespace: xenopus_anatomy
def: "Vein that collects blood from the forelimb via the branchial veins and from the muscles and skin of the trunk via the anterior epigastric and lateral veins." [AAO:0010510]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000060 ! NF stage 48
created_by: eriksegerdell
creation_date: 2012-01-28T05:08:21Z

[Term]
id: XAO:0004255
name: lateral vein
namespace: xenopus_anatomy
def: "Either of the veins that collect blood from the trunk and skin and drain into the subclavian vein." [AAO:0010515]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell

[Term]
id: XAO:0004256
name: ventral abdominal vein
namespace: xenopus_anatomy
def: "A vein formed by the combination of veins in the pelvic region that collects blood from the liver, stomach, intestines, and gall bladder." [AAO:0010517]
is_a: XAO:0000115 ! vein
relationship: part_of XAO:0004423 ! trunk vasculature
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell

[Term]
id: XAO:0004257
name: Jacobson's vein
namespace: xenopus_anatomy
def: "Vein that drains Jacobson's organ." [XAO:curators]
is_a: XAO:0000115 ! vein
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell

[Term]
id: XAO:0004258
name: subpallium
namespace: xenopus_anatomy
def: "Structure that comprises the base region of the telencephalon." [UBERON:0000204]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000012 ! telencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell

[Term]
id: XAO:0004259
name: medial ganglionic eminence
namespace: xenopus_anatomy
def: "A distinct elevation of a transient proliferating cell mass of the subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE." [UBERON:0004024]
synonym: "MGE" EXACT []
xref: UBERON:0004024
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000064 ! NF stage 52
relationship: part_of XAO:0004258 ! subpallium
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell

[Term]
id: XAO:0004260
name: pharyngeal pouch
namespace: xenopus_anatomy
def: "Any of the outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits." [TAO:0001106, XAO:EJS]
synonym: "pharyngeal pouches" RELATED PLURAL []
xref: UBERON:0004117
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0004463 ! pharyngeal endoderm
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: eriksegerdell

[Term]
id: XAO:0004261
name: pharyngeal region
namespace: xenopus_anatomy
def: "Region encompassing the oral end of the alimentary canal." [XAO:EJS]
is_a: XAO:0003186 ! anatomical region
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell

[Term]
id: XAO:0004262
name: ventral caudal lymphatic vessel
namespace: xenopus_anatomy
def: "Lymphatic vessel located in the posterior ventral region of the trunk, ventral to the posterior cardinal vein." [PMID:9048122465]
synonym: "VCLV" EXACT []
is_a: XAO:0000375 ! lymph vessel
created_by: eriksegerdell

[Term]
id: XAO:0004263
name: stylopod
namespace: xenopus_anatomy
def: "Limb segment that is the proximal part of the limb (i.e. the humerus of the forelimb, and the femur of the hindlimb, and surrounding tissues)." [UBERON:0002472]
synonym: "mesopodium" EXACT []
synonym: "stylopodium" EXACT []
xref: UBERON:0002472
is_a: XAO:0004294 ! limb segment
created_by: eriksegerdell

[Term]
id: XAO:0004264
name: zeugopod
namespace: xenopus_anatomy
def: "Limb segment that is the middle part of the limb (i.e. the radio-ulna of the forelimb, and the tarsus and tibia-fibula of the hindlimb, and surrounding tissues)." [UBERON:0002471]
synonym: "metapodium" EXACT []
synonym: "zeugopodium" EXACT []
xref: UBERON:0002471
is_a: XAO:0004294 ! limb segment
created_by: eriksegerdell

[Term]
id: XAO:0004265
name: autopod
namespace: xenopus_anatomy
def: "Limb segment that is the terminal part of the limb (i.e. the metacarpels and phalanges of the forelimb, and the metatarsals and phalanges of the hindlimb, and surrounding tissues)." [XAO:curators]
synonym: "acropodium" EXACT []
synonym: "autopodium" EXACT []
is_a: XAO:0004294 ! limb segment
created_by: eriksegerdell

[Term]
id: XAO:0004266
name: rhombomere R8
namespace: xenopus_anatomy
def: "The 8th and most posterior segment of the developing hindbrain." [XAO:EJS]
synonym: "r8" EXACT []
synonym: "rhombomere 8" EXACT []
is_a: XAO:0004079 ! rhombomere
created_by: eriksegerdell
creation_date: 2012-01-27T10:01:21Z

[Term]
id: XAO:0004267
name: interneuron
namespace: xenopus_anatomy
def: "A multipolar neuron that connects afferent neurons and efferent neurons in neural pathways. They are found within the central nervous system and enteric nervous system." [http://en.wikipedia.org/wiki/Interneuron]
xref: CL:0000099
is_a: XAO:0003023 ! neuron
relationship: part_of XAO:0005195 ! enteric nervous system
created_by: eriksegerdell
creation_date: 2012-01-27T10:24:56Z

[Term]
id: XAO:0004268
name: posterior lateral line
namespace: xenopus_anatomy
def: "A lateral line that extends from the ear in a posterior-ventral direction." [PMID:2652193]
is_a: XAO:0004002 ! lateral line
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell

[Term]
id: XAO:0004269
name: anterodorsal lateral line placode
namespace: xenopus_anatomy
def: "Lateral line placode that gives rise to the anterodorsal lateral line nerve." [XAO:EJS]
synonym: "anterior dorsal lateral line placode" EXACT []
synonym: "antero-dorsal lateral line placode" EXACT []
synonym: "pAD" EXACT []
is_a: XAO:0000440 ! lateral line placode
relationship: develops_from XAO:0004206 ! anterior placodal area
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell

[Term]
id: XAO:0004270
name: hepato-pancreatic progenitor cell
namespace: xenopus_anatomy
def: "Any of a field of cells in the posterior section of the foregut that will give rise to the liver bud and dorsal and ventral pancreatic buds." [XAO:curators]
synonym: "hepato-pancreatic progenitor cells" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0005033 ! progenitor cell
relationship: develops_from XAO:0000101 ! liver diverticulum
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000232 ! foregut
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell

[Term]
id: XAO:0004271
name: midbrain tegmentum
namespace: xenopus_anatomy
def: "Multi-tissue structure that is the ventral part of the midbrain." [UBERON:0001943]
synonym: "Tegm" EXACT []
synonym: "tegmentum" RELATED []
synonym: "tegmentum mesencephali" EXACT []
synonym: "ventral midbrain" RELATED []
xref: UBERON:0001943
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000014 ! midbrain
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-01-28T06:06:15Z

[Term]
id: XAO:0004272
name: migrating neuroblast
namespace: xenopus_anatomy
def: "Any of the neuronal precursor cells that are isolated and scattered throughout the anterior ventro-lateral region of the embryo, generally in a punctate pattern, immediately below the ectoderm." [PMID:17554687, XAO:curators]
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000057 ! NF stage 45
relationship: part_of XAO:0000177 ! nervous system
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: eriksegerdell
creation_date: 2012-02-08T12:22:41Z

[Term]
id: XAO:0004274
name: articular system
namespace: xenopus_anatomy
def: "Anatomical system that consists of all the joints of the body." [UBERON:0004770]
synonym: "joint system" EXACT []
xref: UBERON:0004770
is_a: XAO:0003002 ! anatomical system
relationship: part_of XAO:0003060 ! skeletal system
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0004275
name: axial ossicle
namespace: xenopus_anatomy
def: "Ossicle that is part of the axial skeleton." [UBERON:0011142]
synonym: "vertebral ossicle" RELATED []
xref: UBERON:0011142
is_a: XAO:0004193 ! ossicle
relationship: part_of XAO:0003073 ! postcranial axial skeleton

[Term]
id: XAO:0004276
name: bone element
namespace: xenopus_anatomy
def: "Skeletal element that is composed of bone tissue." [UBERON:0001474]
synonym: "bone" RELATED []
synonym: "bone organ" EXACT []
xref: UBERON:0001474
is_a: XAO:0004012 ! skeletal element
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0004277
name: caudal fin skeleton
namespace: xenopus_anatomy
def: "Median fin skeleton supporting the caudal fin." [VSAO:0000167]
is_a: XAO:0004282 ! median fin skeleton
relationship: part_of XAO:0004062 ! tail fin

[Term]
id: XAO:0004278
name: coracoid
namespace: xenopus_anatomy
def: "Paired bone that is part of the shoulder assembly, joining the scapula to the front end of the sternum." [http://en.wikipedia.org/wiki/Coracoid]
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003063 ! pectoral girdle
relationship: start_stage XAO:1000070 ! NF stage 58

[Term]
id: XAO:0004279
name: cranial skeleton
namespace: xenopus_anatomy
def: "Skeletal subdivision of the head that includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [VSAO:0000049]
is_a: XAO:0004289 ! skeletal subdivision
relationship: part_of XAO:0004011 ! axial skeleton
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0004280
name: dorsal fin skeleton
namespace: xenopus_anatomy
def: "Median fin skeleton located on the dorsal surface of the organism." [VSAO:0000168]
is_a: XAO:0004282 ! median fin skeleton
relationship: part_of XAO:0004063 ! dorsal fin

[Term]
id: XAO:0004281
name: median fin
namespace: xenopus_anatomy
def: "Fin that is an unpaired fin located in the sagittal plane of the organism." [VSAO:0000162]
is_a: XAO:0000002 ! fin
relationship: start_stage XAO:1000046 ! NF stage 31

[Term]
id: XAO:0004282
name: median fin skeleton
namespace: xenopus_anatomy
def: "Postcranial axial skeleton that is unpaired and located on the sagittal plane of the organism." [VSAO:0000170]
synonym: "axial fin skeleton" EXACT []
synonym: "unpaired fin skeleton" EXACT []
is_a: XAO:0004289 ! skeletal subdivision
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004281 ! median fin
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0004283
name: paired appendage
namespace: xenopus_anatomy
def: "Appendage that is one of the anterior or posterior paired appendages (i.e. the forelimbs and hindlimbs)." [XAO:EJS]
is_a: XAO:0000218 ! appendage

[Term]
id: XAO:0004284
name: pectoral appendage
namespace: xenopus_anatomy
def: "Appendage that is one of the anterior paired appendages (i.e. the forelimbs)." [XAO:EJS]
synonym: "anterior paired appendage" EXACT []
is_a: XAO:0004283 ! paired appendage

[Term]
id: XAO:0004285
name: pelvic appendage
namespace: xenopus_anatomy
def: "Appendage that is one of the posterior paired appendages (i.e. the hindlimbs)." [XAO:EJS]
synonym: "posterior paired appendage" EXACT []
is_a: XAO:0004283 ! paired appendage

[Term]
id: XAO:0004286
name: scapula
namespace: xenopus_anatomy
def: "Bone that forms the posterior part of the pectoral (shoulder) girdle." [http://en.wikipedia.org/wiki/Scapula]
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003063 ! pectoral girdle
relationship: start_stage XAO:1000072 ! NF stage 60

[Term]
id: XAO:0004287
name: vertebral centrum
namespace: xenopus_anatomy
def: "Skeletal element that surrounds the notochord." [VSAO:0000183]
synonym: "centrum" RELATED []
is_a: XAO:0004012 ! skeletal element
relationship: part_of XAO:0004288 ! vertebral element
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0004288
name: vertebral element
namespace: xenopus_anatomy
def: "Skeletal element that forms around the notochord and is part of the vertebral column." [UBERON:0010913]
xref: UBERON:0010913
is_a: XAO:0004012 ! skeletal element
relationship: develops_from XAO:0000397 ! sclerotome
relationship: part_of XAO:0003074 ! vertebral column
relationship: start_stage XAO:1000057 ! NF stage 45

[Term]
id: XAO:0004289
name: skeletal subdivision
namespace: xenopus_anatomy
def: "Anatomical cluster consisting of the skeletal elements that are part of the skeleton." [VSAO:0000042]
synonym: "subdivision of skeleton" EXACT []
xref: UBERON:0010912
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004053 ! skeleton
relationship: start_stage XAO:1000040 ! NF stage 24

[Term]
id: XAO:0004290
name: cell part
namespace: xenopus_anatomy
def: "Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher." [CARO:0000014]
synonym: "cell component" EXACT []
xref: CARO:0000014
xref: GO:0044464
is_a: XAO:0003000 ! anatomical structure
relationship: part_of XAO:0003012 ! cell
created_by: eriksegerdell
creation_date: 2012-02-23T11:17:28Z

[Term]
id: XAO:0004291
name: cell-free extract
namespace: xenopus_anatomy_in_vitro
def: "A solution obtained by rupturing cells (especially unfertilized oocytes) and removing all particulate matter." [http://medical-dictionary.thefreedictionary.com/cell-free+extract]
synonym: "cell-free extracts" RELATED PLURAL []
is_a: XAO:0003007 ! anatomical entity in vitro
created_by: eriksegerdell
creation_date: 2012-03-10T01:20:30Z

[Term]
id: XAO:0004292
name: wedge region
namespace: xenopus_anatomy
def: "Region of the oocyte vegetal cortex that contains a subdomain of ER organized on top of the mitochondrial cloud and where localization of Vg1 mRNA takes place." [PMID:15654016]
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000085 ! oocyte stage III
relationship: part_of XAO:0000256 ! oocyte
relationship: start_stage XAO:1000084 ! oocyte stage II
created_by: eriksegerdell
creation_date: 2012-03-10T01:46:15Z

[Term]
id: XAO:0004293
name: ring structure
namespace: xenopus_anatomy
def: "Contractile ring formed at the division plane of the oocyte during first cleavage." [PMID:11942608]
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000092 ! mature egg stage
relationship: part_of XAO:0000256 ! oocyte
relationship: start_stage XAO:1000085 ! oocyte stage III
created_by: eriksegerdell
creation_date: 2012-03-10T01:47:35Z

[Term]
id: XAO:0004294
name: limb segment
namespace: xenopus_anatomy
def: "A major subdivision of a limb." [UBERON:0002529]
is_a: XAO:0003013 ! organism subdivision
relationship: part_of XAO:0003027 ! limb
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-03-10T02:08:16Z

[Term]
id: XAO:0004295
name: forelimb stylopod
namespace: xenopus_anatomy
def: "Stylopod (the limb segment closest to the body) that is part of a forelimb." [UBERON:0003822]
synonym: "upper arm" EXACT []
is_a: XAO:0004263 ! stylopod
relationship: part_of XAO:0003030 ! forelimb
relationship: start_stage XAO:1000068 ! NF stage 56
created_by: eriksegerdell
creation_date: 2012-03-10T02:21:56Z

[Term]
id: XAO:0004296
name: hindlimb stylopod
namespace: xenopus_anatomy
def: "Stylopod (the limb segment closet to the body) that is part of a hindlimb." [XAO:curators]
synonym: "upper leg" EXACT []
is_a: XAO:0004263 ! stylopod
relationship: part_of XAO:0003031 ! hindlimb
created_by: eriksegerdell
creation_date: 2012-03-10T02:22:26Z

[Term]
id: XAO:0004297
name: forelimb zeugopod
namespace: xenopus_anatomy
def: "Limb segment that is the middle part of the forelimb (i.e. the radio-ulna and surrounding tissues)." [XAO:CJZ]
is_a: XAO:0004264 ! zeugopod
relationship: part_of XAO:0003030 ! forelimb
relationship: start_stage XAO:1000068 ! NF stage 56
created_by: eriksegerdell
creation_date: 2012-03-10T02:29:57Z

[Term]
id: XAO:0004298
name: hindlimb zeugopod
namespace: xenopus_anatomy
def: "Limb segment that is the middle part of the hindlimb (i.e. the tarsus and tibia-fibula and surrounding tissues)." [UBERON:0003823]
is_a: XAO:0004264 ! zeugopod
relationship: part_of XAO:0003031 ! hindlimb
created_by: eriksegerdell
creation_date: 2012-03-10T02:30:08Z

[Term]
id: XAO:0004299
name: hand
namespace: xenopus_anatomy
def: "Terminal portion of a forelimb." [UBERON:0002398]
synonym: "front foot" EXACT []
is_a: XAO:0004265 ! autopod
relationship: develops_from XAO:0004490 ! forelimb bud tip
relationship: part_of XAO:0003030 ! forelimb
relationship: start_stage XAO:1000068 ! NF stage 56
created_by: eriksegerdell
creation_date: 2012-03-10T02:45:33Z

[Term]
id: XAO:0004300
name: foot
namespace: xenopus_anatomy
def: "Terminal portion of a hindlimb that bears weight and allows locomotion." [UBERON:0002387]
synonym: "hind foot" EXACT []
is_a: XAO:0004265 ! autopod
relationship: develops_from XAO:0004491 ! hindlimb bud tip
relationship: part_of XAO:0003031 ! hindlimb
created_by: eriksegerdell
creation_date: 2012-03-10T02:45:35Z

[Term]
id: XAO:0004301
name: eminentia thalami
namespace: xenopus_anatomy
def: "Part of the diencephalon that is located between the prethalamus, hypothalamus, and the telencephalon." [XAO:EJS]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:15:31Z

[Term]
id: XAO:0004302
name: pallium
namespace: xenopus_anatomy
def: "Structure that comprises the roof region of the telencephalon." [UBERON:0000203]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000012 ! telencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:21:58Z

[Term]
id: XAO:0004303
name: pretectum
namespace: xenopus_anatomy
def: "Multi-tissue structure that is the dorsal part of the diencephalon and the major sensory input to which is visual." [XAO:EJS, ZFA:0000418]
synonym: "forebrain-midbrain boundary" RELATED []
synonym: "P1" RELATED []
synonym: "prosomere 1" RELATED []
synonym: "PT" EXACT []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:28:09Z

[Term]
id: XAO:0004304
name: prethalamus
namespace: xenopus_anatomy
def: "Multi-tissue structure forming the anterior part of the diencephalon and lying between the thalamus, hypothalamus, and eminentia thalami." [XAO:EJS]
synonym: "P3" RELATED []
synonym: "prosomere 3" RELATED []
synonym: "PTh" EXACT []
synonym: "subthalamus" RELATED []
synonym: "ventral thalamus" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004306 ! thalamus
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:34:32Z

[Term]
id: XAO:0004305
name: zona limitans intrathalamica
namespace: xenopus_anatomy
def: "A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon." [UBERON:0009848]
synonym: "Zli" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:39:28Z

[Term]
id: XAO:0004306
name: thalamus
namespace: xenopus_anatomy
def: "A midline paired symmetrical structure within the brain; the main product of the embryonic diencephalon." [UBERON:0001897]
synonym: "Th" EXACT []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000013 ! diencephalon
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T03:44:52Z

[Term]
id: XAO:0004307
name: head mesenchyme
namespace: xenopus_anatomy
def: "Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head." [XAO:EJS, ZFA:0000113]
synonym: "cephalic mesenchyme" RELATED []
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-03-10T04:21:21Z

[Term]
id: XAO:0004308
name: glial cell
namespace: xenopus_anatomy
def: "Any of the non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain, and for neurons in other parts of the nervous system such as in the autonomic nervous system. Neural crest derived." [XAO:CJZ]
synonym: "glia" RELATED PLURAL []
synonym: "glial cells" RELATED PLURAL []
synonym: "neuroglia" RELATED PLURAL []
synonym: "neuroglial cells" RELATED PLURAL []
xref: CL:0000125
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000048 ! neural crest
relationship: part_of XAO:0000177 ! nervous system
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-03-10T09:44:35Z

[Term]
id: XAO:0004309
name: postmigratory neural crest cell
namespace: xenopus_anatomy
def: "Any of the cells that are of neural crest origin, now in place in their postmigratory target tissues, such as the sciatic nerve, dorsal root ganglia, gut or skin. They can be visualised or detected by specific molecular markers." [XAO:CJZ]
synonym: "postmigratory neural crest cells" RELATED PLURAL []
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-03-10T09:50:34Z

[Term]
id: XAO:0004310
name: stapes
namespace: xenopus_anatomy
def: "Bone of the ear that is connected to the tympanic membrane via the extrastapes. This structure is the amphibian ear ossicle, also known as the columella. It extends between extrastapes cartilage and the oval window. The extrastapes forms a cartilaginous tympanic disk." [ISBN:0520252780, XAO:curators]
synonym: "columella" RELATED []
is_a: XAO:0000214 ! auditory ossicle
is_a: XAO:0004013 ! cartilage element
created_by: eriksegerdell
creation_date: 2012-03-10T10:07:32Z

[Term]
id: XAO:0004311
name: regenerating limb
namespace: xenopus_anatomy
def: "A portion of limb tissue that is re-growing after damage or amputation." [XAO:EJS]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-03-10T10:08:56Z

[Term]
id: XAO:0004312
name: regenerating fin
namespace: xenopus_anatomy
def: "A portion of fin tissue that is re-growing after damage or amputation." [XAO:EJS]
is_a: XAO:0004059 ! regenerating tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000041 ! NF stage 25
created_by: eriksegerdell
creation_date: 2012-03-10T10:10:26Z

[Term]
id: XAO:0004313
name: joint region
namespace: xenopus_anatomy
def: "Anatomical region at which two or more bones make contact and that includes some of the surrounding tissues of various types." [XAO:CJZ]
synonym: "joint" RELATED []
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-03-10T10:13:09Z

[Term]
id: XAO:0004314
name: digit-joint region
namespace: xenopus_anatomy
def: "A joint region within a digit, one of several most distal parts of a limb." [XAO:EJS]
is_a: XAO:0004313 ! joint region
relationship: part_of XAO:0003032 ! digit
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-03-10T10:14:19Z

[Term]
id: XAO:0004315
name: perichondrial cell
namespace: xenopus_anatomy
def: "A cell of the perichondrium, the fibrous membrane of connective tissue covering the surface of cartilage." [http://medical-dictionary.thefreedictionary.com/Perichondrial]
synonym: "perichondrial cells" RELATED PLURAL []
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0004049 ! perichondrium
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell
creation_date: 2012-03-10T10:15:02Z

[Term]
id: XAO:0004316
name: interdigital region
namespace: xenopus_anatomy
def: "Anatomical region between digits, the most distal parts of a limb." [XAO:curators]
is_a: XAO:0003186 ! anatomical region
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-03-10T10:16:20Z

[Term]
id: XAO:0004317
name: amputated tissue
namespace: xenopus_anatomy
def: "A portion of tissue that has been removed from the body." [XAO:EJS]
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2012-03-10T10:19:48Z

[Term]
id: XAO:0004318
name: amputated fin
namespace: xenopus_anatomy
def: "A portion of fin tissue that has been removed from the body." [XAO:EJS]
is_a: XAO:0004317 ! amputated tissue
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000041 ! NF stage 25
created_by: eriksegerdell
creation_date: 2012-03-10T10:22:32Z

[Term]
id: XAO:0004319
name: amputated limb
namespace: xenopus_anatomy
def: "A portion of limb tissue that has been removed from the body." [XAO:EJS]
is_a: XAO:0004317 ! amputated tissue
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-03-10T10:23:05Z

[Term]
id: XAO:0004320
name: mesenchymal stem cell
namespace: xenopus_anatomy
def: "Multipotent stromal cell that can differentiate into a variety of cell types, including: osteoblasts/osteocytes (bone cells), chondroblasts/chondrocytes (cartilage cells), and adipoblasts/adipocytes (fat cells)." [XAO:curators]
synonym: "mesenchymal cell" RELATED []
synonym: "mesenchymal stem cells" RELATED PLURAL []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003054 ! stem cell
relationship: develops_from XAO:0000050 ! mesoderm
relationship: start_stage XAO:1000033 ! NF stage 12.5
created_by: eriksegerdell
creation_date: 2012-03-10T11:14:06Z

[Term]
id: XAO:0004321
name: dorsal caudal lymphatic vessel
namespace: xenopus_anatomy
def: "Lymphatic vessel located in the posterior dorsal region of the trunk." [XAO:EJS]
synonym: "DCLV" EXACT []
is_a: XAO:0000375 ! lymph vessel
created_by: eriksegerdell
creation_date: 2012-03-25T03:48:38Z

[Term]
id: XAO:0004322
name: cranial muscle
namespace: xenopus_anatomy
def: "Any of the muscles that are part of the head." [XAO:curators]
synonym: "head muscle" RELATED []
is_a: XAO:0000172 ! muscle
relationship: develops_from XAO:0004455 ! cranial muscle primordium
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004323
name: mandibular head muscle
namespace: xenopus_anatomy
def: "Any of the paired mandibular arch muscles." [PMID:21050205]
is_a: XAO:0004322 ! cranial muscle
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004324
name: hyoid head muscle
namespace: xenopus_anatomy
def: "Any of the bilateral hyoid arch muscles innervated by cranial nerve VII." [PMID:21050205]
is_a: XAO:0004322 ! cranial muscle
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004325
name: branchial head muscle
namespace: xenopus_anatomy
def: "Any of the muscles that support the filigreed structure of the gill basket necessary for filter feeding, through the stabilisation, extension and compression of the gill basket." [PMID:21050205]
is_a: XAO:0004322 ! cranial muscle
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004326
name: hypobranchial head muscle
namespace: xenopus_anatomy
def: "Straplike muscle that arises from elements of the pectoral girdle and passes to the hyoid bone and laryngeal cartilages." [http://www.britannica.com/EBchecked/topic/279858/hypobranchial-muscle]
is_a: XAO:0004322 ! cranial muscle
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004327
name: eye muscle
namespace: xenopus_anatomy
def: "A muscle that is part of the eye region and controls the movement of the eye." [UBERON:0004277]
is_a: XAO:0004322 ! cranial muscle
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004328
name: m. levator mandibulae longus internus
namespace: xenopus_anatomy
def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. It separates medially from levator mandibulae longus supeficialis, with which it shares a common origin." [PMID:17624928]
synonym: "mlmli" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004425 ! m. levator mandibulae longus internus primordium
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004329
name: m. levator mandibulae longus profundus
namespace: xenopus_anatomy
def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. After separating from levator mandibulae longus superficialis, it parallels it and inserts in the connective tissue. Only at later stages, its rostral third is slightly curved laterally and inserts in the region of the anlage of the tentacular cartilage." [PMID:17624928]
synonym: "mlmlp" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004426 ! m. levator mandibulae longus profundus primordium
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004330
name: m. levator mandibulae longus superficialis
namespace: xenopus_anatomy
def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. The first mandibular arch muscle to appear, it originates ventral to the center of the eye, and extends rostroventrally to end lateral to the buccal cavity." [PMID:17624928]
synonym: "mlmls" EXACT []
synonym: "superior long mandibular levator muscle" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004427 ! m. levator mandibulae longus superior primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004331
name: m. levator mandibulae articularis
namespace: xenopus_anatomy
def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. It originates from the ventral bend of the anlage of processus muscularis palatoquadrati. It runs ventrally near the levator mandibulae longus supeficialis and inserts anterior of it at Meckel's cartilage." [PMID:17624928]
synonym: "articularis mandibular levator muscle" EXACT []
synonym: "mlma" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004428 ! m. levator mandibulae articularis primordium
relationship: start_stage XAO:1000053 ! NF stage 41
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004332
name: m. levator mandibulae externus
namespace: xenopus_anatomy
def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. The last jaw levator to develop, it originates rostral to the palatoquadrate." [PMID:17624928]
synonym: "external mandibular levator muscle" EXACT []
synonym: "mlme" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004429 ! m. levator mandibulae externus primordium
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004333
name: m. intermandibularis
namespace: xenopus_anatomy
def: "Ventral muscle of the larval head that is a broad transverse sheet lying between the Meckel's cartilages and joining its opposite mid-ventrally in an median raphe." [http://jcs.biologists.org/content/s2-81/322/161]
synonym: "intermandibular muscle" EXACT []
synonym: "mim" EXACT []
is_a: XAO:0004323 ! mandibular head muscle
relationship: develops_from XAO:0004430 ! m. intermandibularis primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004334
name: m. quadrato-hyoangularis
namespace: xenopus_anatomy
def: "Hyoid arch muscle that connects Meckel's cartilage with the palatoquadrate and supports the opening of the mouth by depressing Meckel's cartilage." [PMID:21050205]
synonym: "mqh" EXACT []
synonym: "quadrato-hyoangularis muscle" EXACT []
is_a: XAO:0004324 ! hyoid head muscle
relationship: develops_from XAO:0004431 ! m. quadrato-hyoangularis primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004335
name: m. orbitohyoideus
namespace: xenopus_anatomy
def: "Large, tapering muscle that originates on the muscular process and inserts on the ceratohyal." [ISBN:0226557626]
synonym: "moh" EXACT []
synonym: "orbitohyoidal muscle" EXACT []
is_a: XAO:0004324 ! hyoid head muscle
relationship: develops_from XAO:0004432 ! m. orbitohyoideus primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004336
name: m. interhyoideus
namespace: xenopus_anatomy
def: "A thin curved muscle located between the ceratohyal cartilages." [PMID:21050205]
synonym: "interhyoidal muscle" EXACT []
synonym: "mih" EXACT []
is_a: XAO:0004324 ! hyoid head muscle
relationship: develops_from XAO:0004433 ! m. interhyoideus primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004337
name: m. subarcualis rectus I
namespace: xenopus_anatomy
def: "Deep, visceral muscle associated with tongue movement." [AAO:0010659]
synonym: "msr" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004434 ! m. subarcualis rectus I primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004338
name: m. transversus anterior
namespace: xenopus_anatomy
def: "Muscle situated between the planum hypobranchiale and the basihyobranchial, presumably to stabilize the connection between these elements." [PMID:17624928]
synonym: "mta" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004435 ! m. transversus anterior primordium
relationship: start_stage XAO:1000055 ! NF stage 43
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004339
name: m. transversus ventralis II
namespace: xenopus_anatomy
def: "Muscle that springs from the second branchial arch, meeting its opposite in a mid-ventral raphe." [http://jcs.biologists.org/content/s2-81/322/161]
synonym: "mtvII" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004436 ! m. transversus ventralis II primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004340
name: mm. levator arcuum branchialium I
namespace: xenopus_anatomy
def: "The 1st branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS]
synonym: "mlabI" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004437 ! mm. levator arcuum branchialium I primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004341
name: mm. levator arcuum branchialium II
namespace: xenopus_anatomy
def: "The 2nd branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS]
synonym: "mlabII" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004438 ! mm. levator arcuum branchialium II primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004342
name: mm. levator arcuum branchialium III
namespace: xenopus_anatomy
def: "The 3rd branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS]
synonym: "mlabIII" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004439 ! mm. levator arcuum branchialium III primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004343
name: mm. levator arcuum branchialium IV
namespace: xenopus_anatomy
def: "The 4th branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS]
synonym: "mlabIV" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004440 ! mm. levator arcuum branchialium IV primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004344
name: mm. constrictores branchiales II
namespace: xenopus_anatomy
def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It originates on the ventrolateral process of the palatoquadrate." [http://jcs.biologists.org/content/s2-81/322/161]
synonym: "mcbII" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004441 ! mm. constrictores branchiales II primordium
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004345
name: mm. constrictores branchiales III
namespace: xenopus_anatomy
def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It is located on the crista parotica and commissura branchio-cranialis." [http://jcs.biologists.org/content/s2-81/322/161]
synonym: "mcbIII" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004442 ! mm. constrictores branchiales III primordium
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004346
name: mm. constrictores branchiales IV
namespace: xenopus_anatomy
def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It is a small muscle situated at the posterior end of the branchial skeleton." [http://jcs.biologists.org/content/s2-81/322/161]
synonym: "mcbIV" EXACT []
is_a: XAO:0004325 ! branchial head muscle
relationship: develops_from XAO:0004443 ! mm. constrictores branchiales IV primordium
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004349
name: m. constrictor laryngis
namespace: xenopus_anatomy
def: "Muscle that consists of dorsal and ventral parts that arise from medial raphe and insert on the arytenoid cartilages." [ISBN:0226557626]
is_a: XAO:0004351 ! laryngeal muscle
relationship: develops_from XAO:0004446 ! m. constrictor laryngis primordium
relationship: start_stage XAO:1000055 ! NF stage 43
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004350
name: m. dilatator laryngis
namespace: xenopus_anatomy
def: "Muscle that arises from the edge of levator arcus branchialis IV and inserts on the arytenoid cartilage and the cricoid ring." [ISBN:0226557626]
is_a: XAO:0004351 ! laryngeal muscle
relationship: develops_from XAO:0004447 ! m. dilatator laryngis primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004351
name: laryngeal muscle
namespace: xenopus_anatomy
def: "Type of muscle that attaches to the larynx." [XAO:EJS]
synonym: "LM" EXACT []
is_a: XAO:0004322 ! cranial muscle
relationship: develops_from XAO:0004448 ! laryngeal muscle primordium
relationship: start_stage XAO:1000054 ! NF stage 42
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004352
name: m. rectus anterior
namespace: xenopus_anatomy
def: "Muscle in the orbit that inserts on the anterior side of the eye and the function of which is adduction of the eyeball." [XAO:curators]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004449 ! m. rectus anterior primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004353
name: m. rectus posterior
namespace: xenopus_anatomy
def: "Muscle in the orbit that inserts on the posterior side of the eye and the function of which is adduction of the eyeball." [XAO:curators]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004450 ! m. rectus posterior primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004354
name: m. rectus inferior
namespace: xenopus_anatomy
def: "Muscle in the orbit that depresses, adducts, and helps extort (rotate laterally) the eye." [UBERON:0006322]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004451 ! m. rectus inferior primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004355
name: m. rectus superior
namespace: xenopus_anatomy
def: "Muscle in the orbit, the primary function is of which is elevation." [UBERON:0006323]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004452 ! m. rectus superior primordium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004356
name: m. obliquus inferior
namespace: xenopus_anatomy
def: "Thin, narrow muscle placed near the anterior margin of the floor of the orbit." [UBERON:0006320]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004453 ! m. obliquus inferior primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004357
name: m. obliquus superior
namespace: xenopus_anatomy
def: "Muscle in the upper, medial side of the orbit whose primary action is downward, lateral rotation of the eye." [UBERON:0006321]
is_a: XAO:0004327 ! eye muscle
relationship: develops_from XAO:0004454 ! m. obliquus superior primordium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004358
name: basihyal
namespace: xenopus_anatomy
alt_id: XAO:0004382
def: "Cartilaginous element that is median and is the anterior-most cartilage of the ventral hyoid arch." [UBERON:0011615]
synonym: "basihyobranchial" EXACT []
synonym: "bhb" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004359
name: ceratobranchial I
namespace: xenopus_anatomy
def: "The cartilaginous element below the epibranchial in branchial arch 1." [http://www.thefreedictionary.com/Ceratobranchial]
synonym: "cbl-I" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004360
name: ceratobranchial II
namespace: xenopus_anatomy
def: "The cartilaginous element below the epibranchial in branchial arch 2." [http://www.thefreedictionary.com/Ceratobranchial]
synonym: "cbl-II" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004361
name: ceratobranchial III
namespace: xenopus_anatomy
def: "The cartilaginous element below the epibranchial in branchial arch 3." [http://www.thefreedictionary.com/Ceratobranchial]
synonym: "cbl-III" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004362
name: ceratobranchial IV
namespace: xenopus_anatomy
def: "The cartilaginous element below the epibranchial in branchial arch 4." [http://www.thefreedictionary.com/Ceratobranchial]
synonym: "cbl-IV" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004363
name: commisura quadratocranialis anterior
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the rostral connection of the palatoquadrate cartilage to the neurocranium." [PMID:21050205]
synonym: "cqca" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004364
name: cornua trabecula
namespace: xenopus_anatomy
def: "Cartilaginous element that supports the anterior end of the nasal organ." [ISBN:1276806469]
synonym: "cornua trabeculae" RELATED PLURAL []
synonym: "ct" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004365
name: fenestra basicranialis
namespace: xenopus_anatomy
def: "The space where the trabeculae of the tadpole chondrocranium have not yet fused." [ISBN:0226557626]
synonym: "fbc" EXACT []
is_a: XAO:0003190 ! anatomical space
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004366
name: facies hyoidis of the palatoquadrate
namespace: xenopus_anatomy
def: "One of the cartilaginous surfaces of the tadpole jaw." [XAO:curators]
synonym: "fhpq" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004367
name: fenestra subocularis
namespace: xenopus_anatomy
def: "The wide gap that separates the palatoquadrate from the neurocranium." [ISBN:0226557626]
synonym: "fso" EXACT []
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0003059 ! chondrocranium
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004368
name: infrarostral
namespace: xenopus_anatomy
def: "Cartilaginous element comprising cartilages that articulate with Meckel's cartilage in the lower jaw and are fused medially." [PMID:21050205]
synonym: "io" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004369
name: processus anterior hyalis
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the anterior process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205]
synonym: "pach" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004370
name: processus articularis palatoquadrati
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the articular process that forms the jaw joint with the posterior end of Meckel's cartilage." [ISBN:0226557626]
synonym: "parpq" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004371
name: processus ascendens palatoquadrate
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the ascending process that helps anchor the larval palatoquadrate to the neurocranium." [ISBN:0226557626]
synonym: "paspq" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004372
name: parachordal
namespace: xenopus_anatomy
def: "Rod-shaped paired cartilages located on either side of the notochord and involved in the formation of the base of the chondrochranium." [TAO:0001423, XAO:EJS]
synonym: "parachordal cartilage" RELATED []
synonym: "pk" EXACT []
xref: UBERON:0009635
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004373
name: processus lateralis hyalis
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the lateral process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205]
synonym: "plch" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004374
name: planum hypobranchiale
namespace: xenopus_anatomy
alt_id: XAO:0004383
def: "One of the cartilaginous elements that meet and articulate in the median plane posterior to the basibranchial." [http://amphibiatree.org/node/407]
synonym: "plana hypobranchiale" RELATED PLURAL []
synonym: "plhb" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004375
name: planum trabeculare anticum
namespace: xenopus_anatomy
def: "Cartilaginous element that is posterior to the cornua trabeculae." [XAO:curators]
synonym: "ethmoid plate" RELATED []
synonym: "planum ethmoidale" RELATED []
synonym: "plta" EXACT []
synonym: "trabecular plate" RELATED []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004376
name: processus muscularis palatoquadrati
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the muscular process, a flattened triangular process that is the site of attachment for the orbitohyoideus and suspensoriohyoideus muscles." [ISBN:0226557626]
synonym: "pmpq" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004377
name: processus posterior hyalis
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the posterior process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205]
synonym: "ppch" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004378
name: palatoquadrati
namespace: xenopus_anatomy
def: "Cartilaginous element comprising the dorsal component of the mandibular arch." [UBERON:0004752]
synonym: "palatoquadrate cartilage" EXACT []
synonym: "pq" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004379
name: processus retroarticularis of Meckel's cartilage
namespace: xenopus_anatomy
def: "Cartilaginous element that forms at the posteroventral tip of Meckel's cartilage." [XAO:EJS, ZFA:0000422]
synonym: "prmc" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: part_of XAO:0003059 ! chondrocranium
relationship: part_of XAO:0003085 ! Meckel's cartilage
relationship: start_stage XAO:1000055 ! NF stage 43
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004380
name: suprarostral plate
namespace: xenopus_anatomy
def: "Cartilaginous element that comprises a crescent-shaped plate that supports the tentacular cartilage in the upper jaw." [PMID:21050205]
synonym: "sp" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004381
name: trabecula cranii
namespace: xenopus_anatomy
def: "Cartilaginous element comprising a pair of chondrification centers in the base of the embryonic cartilaginous neurocranium." [http://www.medilexicon.com/medicaldictionary.php?t=92818]
synonym: "tc" EXACT []
synonym: "trabeculae cranii" RELATED PLURAL []
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003059 ! chondrocranium
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004384
name: peripheral vegetal yolk mass
namespace: xenopus_anatomy
def: "Peripherally located part of the vegetal cell mass of prospective endoderm." [XAO:EJS]
synonym: "peripheral vegetal cell mass" EXACT []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000281 ! vegetal yolk mass
created_by: eriksegerdell
creation_date: 2012-05-31T02:56:10Z

[Term]
id: XAO:0004385
name: branchial basket
namespace: xenopus_anatomy
alt_id: XAO:0004386
def: "Cartilaginous element that comprises the network-like cartilaginous skeleton of the gill region." [UBERON:0009119]
synonym: "gill basket" EXACT []
is_a: XAO:0004013 ! cartilage element
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004387
name: retinal stem cell region
namespace: xenopus_anatomy
def: "Region of the ciliary marginal zone, at the edge (most distal region) where retinal stem cells are located." [PMID:7695895]
synonym: "ciliary marginal zone stem cell region" EXACT []
synonym: "CMZ stem cell region" EXACT []
synonym: "RSCR" EXACT []
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000086 ! ciliary marginal zone
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004388
name: retinal progenitor cell region
namespace: xenopus_anatomy
def: "Region of the ciliary marginal zone where retinal progenitor cells are located." [PMID:7695895]
synonym: "ciliary marginal zone progenitor cell region" EXACT []
synonym: "CMZ progenitor cell region" EXACT []
synonym: "RPCR" EXACT []
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000086 ! ciliary marginal zone
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004389
name: oculomotor motornucleus
namespace: xenopus_anatomy
def: "Ganglion in the midbrain that gives rise to the fibers of the oculomotor nerve." [XAO:KAB]
synonym: "oculomotor nucleus" RELATED []
synonym: "OM" EXACT []
xref: UBERON:0001715
is_a: XAO:0004609 ! neural nucleus
relationship: develops_from XAO:0000042 ! neuroectoderm
relationship: part_of XAO:0000014 ! midbrain
relationship: part_of XAO:0000027 ! cranial ganglion
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004390
name: dorsal thalamus
namespace: xenopus_anatomy
def: "Multi-tissue structure that is the dorsal part of the thalamus and emerges ventral to the caudal portion of the ventral habenular nucleus." [XAO:EJS, ZFA:0000653]
synonym: "DT" EXACT []
synonym: "epithalamus" RELATED []
synonym: "P2" RELATED []
synonym: "prosomere 2" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004306 ! thalamus
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004391
name: trochlear motornucleus
namespace: xenopus_anatomy
def: "The nucleus of the trochlear nerve (cranial nerve IV)." [XAO:EJS]
synonym: "TM" EXACT []
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000014 ! midbrain
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004392
name: goblet cell
namespace: xenopus_anatomy
def: "A type of mucus surface cell in the tadpole." [ISBN:080184780X]
synonym: "goblet cells" RELATED PLURAL []
is_a: XAO:0003249 ! epithelial cell
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000023 ! skin
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004393
name: mucociliary epithelium
namespace: xenopus_anatomy
def: "Type of epithelium in the embryonic epidermis that is mucus-secreting and ciliated." [XAO:curators]
is_a: XAO:0003045 ! epithelium
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000028 ! epidermis
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004394
name: hatching gland primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the hatching gland, present by the end of gastrulation." [XAO:EJS]
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0004091 ! non-neural ectoderm
relationship: end_stage XAO:1000024 ! NF stage 14
relationship: part_of XAO:0003024 ! head
relationship: start_stage XAO:1000033 ! NF stage 12.5
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004395
name: central vegetal yolk mass
namespace: xenopus_anatomy
def: "Centrally located part of the vegetal cell mass of prospective endoderm." [XAO:EJS]
synonym: "central vegetal cell mass" EXACT []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000022 ! NF stage 12
relationship: part_of XAO:0000281 ! vegetal yolk mass
created_by: eriksegerdell
creation_date: 2012-05-31T02:57:12Z

[Term]
id: XAO:0004396
name: apical mesenchyme
namespace: xenopus_anatomy
def: "Regenerating tissue consisting of mesenchyme cells at the tip of the regenerating limb." [XAO:EJS]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004060 ! blastema
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004397
name: wound epidermis
namespace: xenopus_anatomy
def: "A layer of epidermal cells that initially covers the surface of an amputation site. Fibroblasts from the surrounding connective tissue migrate across the amputation surface to meet at the center of the wound. These fibroblasts multiply to form a blastema, which are the progenitors for the new limb." [XAO:CJZ]
synonym: "apical wound epidermis" RELATED []
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004398
name: wound epidermis inner layer
namespace: xenopus_anatomy
def: "Regenerating tissue that forms the inner or basal layer of wound epidermis." [XAO:EJS]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004397 ! wound epidermis
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004399
name: wound epidermis outer layer
namespace: xenopus_anatomy
def: "Regenerating tissue that forms the outer layer of wound epidermis." [XAO:EJS]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004397 ! wound epidermis
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004400
name: regenerating zeugopod skeleton
namespace: xenopus_anatomy
def: "Tissue consisting of a cartilaginous rod or rods of a regenerating zeugopod segment of a limb." [XAO:curators]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004311 ! regenerating limb
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004401
name: apical epithelial cap
namespace: xenopus_anatomy
def: "A layer of signaling cells at the apex of a regenerating blastema, which has a vital role in regeneration." [XAO:CJZ]
synonym: "AEC" EXACT []
is_a: XAO:0004059 ! regenerating tissue
relationship: develops_from XAO:0004397 ! wound epidermis
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004402
name: pseudoblastema
namespace: xenopus_anatomy
def: "Following amputation in late prometamorphosis or in young froglets, tissue comprising fibroblast-like cells in a limb stump that aggregate beneath the wound epithelia." [ISBN:3540228713]
is_a: XAO:0004059 ! regenerating tissue
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004403
name: fibrocellular pad
namespace: xenopus_anatomy
def: "Regenerative tissue that develops and covers cut bone in the tadpole." [PMID:10906786]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004060 ! blastema
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004404
name: keratinocyte
namespace: xenopus_anatomy
def: "The predominant cell type in the epidermis, the primary function of which is the formation of a barrier against environmental damage." [http://en.wikipedia.org/wiki/Keratinocyte]
synonym: "keratinocytes" RELATED PLURAL []
is_a: XAO:0003252 ! keratin accumulating cell
relationship: part_of XAO:0000028 ! epidermis
relationship: part_of XAO:0004060 ! blastema
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004405
name: Leydig cell
namespace: xenopus_anatomy
def: "A type of special epithelial cell that secretes mucus into the subsurface extracellular compartments of the epidermis." [ISBN:080184780X]
synonym: "Leydig cells" RELATED PLURAL []
synonym: "Leydig gland cell" RELATED []
is_a: XAO:0003249 ! epithelial cell
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000028 ! epidermis
relationship: part_of XAO:0004060 ! blastema
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004406
name: presumptive axial mesoderm
namespace: xenopus_anatomy
def: "Presumptive structure that will develop into axial mesoderm." [XAO:EJS]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000072 ! dorsal marginal zone
relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm
relationship: end_stage XAO:1000033 ! NF stage 12.5
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004407
name: proximal mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme that occupies the proximal region of a limb bud." [XAO:EJS]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004408
name: anterior-proximal mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme that occupies the anterior proximal region of a limb bud." [XAO:EJS]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004409
name: posterior-proximal mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme that occupies the posterior proximal region of a limb bud." [XAO:EJS]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004410
name: interdigital mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme that occupies the interdigital region of a limb bud." [XAO:EJS]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000068 ! NF stage 56
relationship: part_of XAO:0003161 ! limb bud
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004411
name: lateral line primordium
namespace: xenopus_anatomy
def: "Portion of tissue that migrates and deposits immature neuromasts and interneuromasts." [XAO:EJS, ZFA:0000228]
is_a: XAO:0003043 ! primordium
relationship: part_of XAO:0000095 ! lateral line system
relationship: start_stage XAO:1000048 ! NF stage 33 and 34
created_by: eriksegerdell
creation_date: 2012-05-31T08:03:05Z

[Term]
id: XAO:0004412
name: hindlimb digit 2
namespace: xenopus_anatomy
def: "The 2nd most posterior of the hind digits, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ]
synonym: "hind digit 2" EXACT []
synonym: "pedal digit 2" EXACT []
synonym: "toe 2" EXACT []
synonym: "toe II" EXACT []
is_a: XAO:0003035 ! hindlimb digit
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004413
name: hindlimb digit 3
namespace: xenopus_anatomy
def: "The 3rd most posterior, or middle, of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "hind digit 3" EXACT []
synonym: "pedal digit 3" EXACT []
synonym: "toe 3" EXACT []
synonym: "toe III" EXACT []
is_a: XAO:0003035 ! hindlimb digit
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004414
name: hindlimb digit 4
namespace: xenopus_anatomy
def: "The 2nd most anterior of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "hind digit 4" EXACT []
synonym: "pedal digit 4" EXACT []
synonym: "toe 4" EXACT []
synonym: "toe IV" EXACT []
is_a: XAO:0003035 ! hindlimb digit
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004415
name: hindlimb digit 5
namespace: xenopus_anatomy
def: "The most anterior and longest of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "hind digit 5" EXACT []
synonym: "pedal digit 5" EXACT []
synonym: "toe 5" EXACT []
synonym: "toe V" EXACT []
is_a: XAO:0003035 ! hindlimb digit
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004416
name: claw primordium
namespace: xenopus_anatomy
def: "Portion of tissue consisting of unkeratinized cells at the most distal end of a developing digit and which will become a claw." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000001 ! ectoderm
relationship: end_stage XAO:1000069 ! NF stage 57
relationship: part_of XAO:0003035 ! hindlimb digit
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004417
name: claw of hindlimb digit 1
namespace: xenopus_anatomy
def: "Claw located at the end of the 1st hindlimb digit." [XAO:EJS]
synonym: "claw of hind digit 1" EXACT []
is_a: XAO:0003103 ! claw
relationship: part_of XAO:0004239 ! hindlimb digit 1
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004418
name: claw of hindlimb digit 2
namespace: xenopus_anatomy
def: "Claw located at the end of the 2nd hindlimb digit." [XAO:EJS]
synonym: "claw of hind digit 2" EXACT []
is_a: XAO:0003103 ! claw
relationship: part_of XAO:0004412 ! hindlimb digit 2
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004419
name: claw of hindlimb digit 3
namespace: xenopus_anatomy
def: "Claw located at the end of the 3rd hindlimb digit." [XAO:EJS]
synonym: "claw of hind digit 3" EXACT []
is_a: XAO:0003103 ! claw
relationship: part_of XAO:0004413 ! hindlimb digit 3
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004420
name: claw of hindlimb digit 4
namespace: xenopus_anatomy
def: "Claw located at the end of the 4th hindlimb digit." [XAO:EJS]
synonym: "claw of hind digit 4" EXACT []
is_a: XAO:0003103 ! claw
relationship: part_of XAO:0004414 ! hindlimb digit 4
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004421
name: claw of hindlimb digit 5
namespace: xenopus_anatomy
def: "Claw located at the end of the 5th hindlimb digit." [XAO:EJS]
synonym: "claw of hind digit 5" EXACT []
is_a: XAO:0003103 ! claw
relationship: part_of XAO:0004415 ! hindlimb digit 5
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004422
name: posterior lateral line ganglion
namespace: xenopus_anatomy
def: "Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate the posterior lateral line system." [XAO:EJS, ZFA:0001314]
synonym: "posterior lateral line ganglia" RELATED PLURAL []
is_a: XAO:0004457 ! lateral line ganglion
created_by: eriksegerdell
creation_date: 2012-05-05T05:15:00Z

[Term]
id: XAO:0004423
name: trunk vasculature
namespace: xenopus_anatomy
def: "The blood vessels of the trunk region." [XAO:EJS]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000100 ! cardiovascular system
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000035 ! NF stage 19
created_by: eriksegerdell
creation_date: 2012-05-26T05:47:10Z

[Term]
id: XAO:0004424
name: central retina
namespace: xenopus_anatomy
def: "Anatomical region comprising the central part of the retina." [XAO:EJS]
is_a: XAO:0003186 ! anatomical region
relationship: part_of XAO:0000009 ! retina
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell
creation_date: 2012-07-01T02:33:21Z

[Term]
id: XAO:0004425
name: m. levator mandibulae longus internus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator mandibulae longus internus muscle." [XAO:EJS]
synonym: "mlmli" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004426
name: m. levator mandibulae longus profundus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator mandibulae longus profundus muscle." [XAO:EJS]
synonym: "mlmlp" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004427
name: m. levator mandibulae longus superior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator mandibulae longus superior muscle." [XAO:EJS]
synonym: "mlmls" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004428
name: m. levator mandibulae articularis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator mandibulae articularis muscle." [XAO:EJS]
synonym: "mlma" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004429
name: m. levator mandibulae externus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator mandibulae externus muscle." [XAO:EJS]
synonym: "mlme" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: start_stage XAO:1000056 ! NF stage 44
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004430
name: m. intermandibularis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the intermandibularis muscle." [XAO:EJS]
synonym: "mim" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004431
name: m. quadrato-hyoangularis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the quadrato-hyoangularis muscle." [XAO:EJS]
synonym: "mqh" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004432
name: m. orbitohyoideus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the orbitohyoideus muscle." [XAO:EJS]
synonym: "moh" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004433
name: m. interhyoideus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the interhyoideus muscle." [XAO:EJS]
synonym: "mih" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004434
name: m. subarcualis rectus I primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the subarcualis rectus I muscle." [XAO:EJS]
synonym: "msr" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004435
name: m. transversus anterior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the transversus anterior muscle." [XAO:EJS]
synonym: "mta" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000054 ! NF stage 42
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004436
name: m. transversus ventralis II primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the transversus ventralis II muscle." [XAO:EJS]
synonym: "mtvII" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004437
name: mm. levator arcuum branchialium I primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator arcuum branchialium I muscles." [XAO:EJS]
synonym: "mlabI" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004438
name: mm. levator arcuum branchialium II primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator arcuum branchialium II muscles." [XAO:EJS]
synonym: "mlabII" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004439
name: mm. levator arcuum branchialium III primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator arcuum branchialium III muscles." [XAO:EJS]
synonym: "mlabIII" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004440
name: mm. levator arcuum branchialium IV primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the levator arcuum branchialium IV muscles." [XAO:EJS]
synonym: "mlabIV" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000052 ! NF stage 40
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004441
name: mm. constrictores branchiales II primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the constrictores branchiales II muscles." [XAO:EJS]
synonym: "mcbII" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004442
name: mm. constrictores branchiales III primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the constrictores branchiales III muscles." [XAO:EJS]
synonym: "mcbIII" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004443
name: mm. constrictores branchiales IV primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the constrictores branchiales IV muscles." [XAO:EJS]
synonym: "mcbIV" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004444
name: m. geniohyoideus primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the geniohyoideus muscle." [XAO:EJS]
synonym: "mgh" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004445
name: m. rectus cervicis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the rectus cervicis muscle." [XAO:EJS]
synonym: "mrc" RELATED []
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004446
name: m. constrictor laryngis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the constrictor laryngis muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000054 ! NF stage 42
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004447
name: m. dilatator laryngis primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the dilatator laryngis muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004448
name: laryngeal muscle primordium
namespace: xenopus_anatomy
def: "The presumptive cells of laryngeal muscle." [XAO:EJS]
is_a: XAO:0003043 ! primordium
relationship: end_stage XAO:1000053 ! NF stage 41
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004449
name: m. rectus anterior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the rectus anterior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004450
name: m. rectus posterior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the rectus posterior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004451
name: m. rectus inferior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the rectus inferior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004452
name: m. rectus superior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the rectus superior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000051 ! NF stage 39
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004453
name: m. obliquus inferior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the obliquus inferior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004454
name: m. obliquus superior primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the obliquus superior muscle." [XAO:EJS]
is_a: XAO:0004455 ! cranial muscle primordium
relationship: end_stage XAO:1000050 ! NF stage 37 and 38
created_by: eriksegerdell
creation_date: 2012-05-30T09:49:00Z

[Term]
id: XAO:0004455
name: cranial muscle primordium
namespace: xenopus_anatomy
def: "The presumptive cells of any of the cranial muscles." [XAO:EJS]
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0000053 ! head mesoderm
relationship: end_stage XAO:1000057 ! NF stage 45
relationship: part_of XAO:0004042 ! muscular system
relationship: start_stage XAO:1000047 ! NF stage 32
created_by: eriksegerdell
creation_date: 2012-05-30T10:00:01Z

[Term]
id: XAO:0004456
name: Brachet's cleft
namespace: xenopus_anatomy
def: "A sharp boundary, running parallel to the outside of the embryo, between involuted mesoderm and external ectoderm. It runs from the blastopore to the upper limit of the involuted mesoderm." [PMID:21464931]
synonym: "Brachy's cleft" EXACT []
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000037 ! NF stage 21
relationship: start_stage XAO:1000021 ! NF stage 11
created_by: eriksegerdell
creation_date: 2012-05-31T11:43:41Z

[Term]
id: XAO:0004457
name: lateral line ganglion
namespace: xenopus_anatomy
def: "Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate a lateral line." [XAO:EJS, ZFA:0000120]
synonym: "lateral line ganglia" RELATED PLURAL []
is_a: XAO:0000027 ! cranial ganglion
relationship: part_of XAO:0000095 ! lateral line system
created_by: eriksegerdell
creation_date: 2012-05-31T08:16:22Z

[Term]
id: XAO:0004458
name: peripheral retina
namespace: xenopus_anatomy
def: "Anatomical region comprising the peripheral part of the retina." [XAO:EJS]
is_a: XAO:0003186 ! anatomical region
relationship: part_of XAO:0000009 ! retina
relationship: start_stage XAO:1000044 ! NF stage 28
created_by: eriksegerdell
creation_date: 2012-07-01T02:33:47Z

[Term]
id: XAO:0004459
name: subocular cartilage
namespace: xenopus_anatomy
def: "Cartilaginous element that is below the trabecula and parachordal." [XAO:curators]
is_a: XAO:0004013 ! cartilage element
relationship: develops_from XAO:0003205 ! chondrocyte
created_by: eriksegerdell
creation_date: 2012-09-09T03:24:03Z

[Term]
id: XAO:0004460
name: choroid
namespace: xenopus_anatomy
def: "Portion of tissue comprising the vascular layer of the eye, containing connective tissue and lying between the retina and the sclera. It provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, it forms the uveal tract." [http://en.wikipedia.org/wiki/Choroid, XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0000179 ! eye
relationship: part_of XAO:0004529 ! uveal tract
relationship: start_stage XAO:1000056 ! NF stage 44
created_by: eriksegerdell
creation_date: 2012-09-09T03:31:52Z

[Term]
id: XAO:0004461
name: circumpharyngeal ridge
namespace: xenopus_anatomy
def: "Site above the branchial arch complex where vagal neural crest cells temporarily arrest their migration before entering the pharyngeal arches and heart." [XAO:curators]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0004191 ! vagal neural crest
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000038 ! NF stage 22
created_by: eriksegerdell
creation_date: 2012-09-09T03:40:23Z

[Term]
id: XAO:0004462
name: dorsal endoderm
namespace: xenopus_anatomy
def: "Single cell layer of involuted endoderm lying beneath the prechordal plate." [XAO:curators]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000034 ! NF stage 18
relationship: part_of XAO:0000094 ! gastrocoel roof plate
relationship: start_stage XAO:1000021 ! NF stage 11
created_by: eriksegerdell
creation_date: 2012-09-09T03:50:45Z

[Term]
id: XAO:0004463
name: pharyngeal endoderm
namespace: xenopus_anatomy
def: "Embryonic endoderm that evaginates to form the paired pharyngeal pouches." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0000090 ! endoderm
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000090 ! endoderm
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2012-09-09T04:08:58Z

[Term]
id: XAO:0004464
name: rhombomere R1
namespace: xenopus_anatomy
def: "The most anterior segment of the developing hindbrain." [XAO:curators]
synonym: "r1" EXACT []
synonym: "rhombomere 1" RELATED []
is_a: XAO:0004079 ! rhombomere
created_by: eriksegerdell
creation_date: 2012-09-09T04:24:23Z

[Term]
id: XAO:0004465
name: endolymphatic duct
namespace: xenopus_anatomy
def: "Canal that connects the membranous labyrinth of the ear with the endolymphatic sac." [http://medical-dictionary.thefreedictionary.com/endolymphatic+duct]
is_a: XAO:0004000 ! duct
relationship: develops_from XAO:0000196 ! sacculus
relationship: part_of XAO:0000192 ! inner ear
relationship: start_stage XAO:1000059 ! NF stage 47
created_by: eriksegerdell
creation_date: 2012-09-09T04:31:49Z

[Term]
id: XAO:0004466
name: serous membrane
namespace: xenopus_anatomy
def: "Multi-tissue structure that comprises a secretory epithelial layer and a connective tissue layer." [http://en.wikipedia.org/wiki/Serous_membrane]
synonym: "serosa" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2012-09-18T03:32:10Z

[Term]
id: XAO:0004467
name: zygote cortex
namespace: xenopus_anatomy
def: "Cell component comprising the outer layers of the zygote." [XAO:EJS]
is_a: XAO:0004290 ! cell part
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: part_of XAO:0000035 ! zygote
relationship: start_stage XAO:1000001 ! NF stage 1
created_by: eriksegerdell
creation_date: 2012-09-18T03:50:25Z

[Term]
id: XAO:0004468
name: organ cortex
namespace: xenopus_anatomy
def: "Multi-tissue structure that is the outermost layer of an organ." [UBERON:0001851]
is_a: XAO:0003037 ! multi-tissue structure
relationship: start_stage XAO:1000037 ! NF stage 21
created_by: eriksegerdell
creation_date: 2012-09-18T03:51:06Z

[Term]
id: XAO:0004469
name: trabecula
namespace: xenopus_anatomy
def: "A small tissue element in the form of a beam, strut, or rod that generally has a mechanical function and is usually composed of dense cartilaginous tissue." [http://en.wikipedia.org/wiki/Trabecula]
synonym: "trabeculae" RELATED PLURAL []
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000052 ! NF stage 40

[Term]
id: XAO:0004470
name: trabecula carnea
namespace: xenopus_anatomy
def: "A type of trabecula that consists of a rounded or irregular column that projects from the inner surface of the ventricle of the heart." [http://en.wikipedia.org/wiki/Trabeculae_carneae]
synonym: "trabeculae carneae" RELATED PLURAL []
is_a: XAO:0004469 ! trabecula
relationship: develops_from XAO:0000065 ! myocardium
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000053 ! NF stage 41

[Term]
id: XAO:0004471
name: atrial septum
namespace: xenopus_anatomy
def: "Cardiac septum that separates the right atrium from the left atrium." [UBERON:0002085]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0004472
name: sinus venosus
namespace: xenopus_anatomy
def: "A large quadrangular cavity that precedes the atrium on the venous side of the heart." [http://en.wikipedia.org/wiki/Sinus_venosus]
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000064 ! heart
relationship: start_stage XAO:1000044 ! NF stage 28

[Term]
id: XAO:0004473
name: ventral mesoderm
namespace: xenopus_anatomy
def: "Embryonic structure that is induced by the organizer to become lateral mesoderm." [http://en.wikipedia.org/wiki/Regional_specification]
xref: UBERON:2000083
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000084 ! involuted ventral mesoderm
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000026 ! NF stage 16
created_by: eriksegerdell
creation_date: 2013-03-15T20:23:49Z

[Term]
id: XAO:0004474
name: periotic region
namespace: xenopus_anatomy
def: "Anatomical region that surrounds the otic vesicle." [XAO:curators]
synonym: "periotic mesenchyme" RELATED []
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000070 ! NF stage 58
relationship: part_of XAO:0000040 ! head region
relationship: start_stage XAO:1000041 ! NF stage 25
created_by: eriksegerdell
creation_date: 2013-03-17T11:59:34Z

[Term]
id: XAO:0004475
name: myocyte
namespace: xenopus_anatomy
def: "A mature contractile cell, which has as part of its cytoplasm myofibrils organized in various patterns. Found in muscle tissue, myocytes are long, tubular cells that arise developmentally from myoblasts to form muscle. There are specialized forms: cardiac, skeletal, and smooth muscle myocytes, with various properties." [CL:0000187, XAO:curators]
synonym: "muscle cell" RELATED []
synonym: "muscle cells" RELATED PLURAL []
synonym: "muscle fiber" RELATED []
synonym: "myocytes" RELATED PLURAL []
xref: CL:0000187
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0003015 ! myoblast
relationship: part_of XAO:0000172 ! muscle
relationship: start_stage XAO:1000043 ! NF stage 27
created_by: eriksegerdell
creation_date: 2013-03-17T12:20:58Z

[Term]
id: XAO:0004476
name: skeletal myocyte
namespace: xenopus_anatomy
def: "A myocyte of the skeletal muscle." [XAO:curators]
synonym: "skeletal muscle cell" RELATED []
synonym: "skeletal muscle cells" RELATED PLURAL []
synonym: "skeletal myocytes" RELATED PLURAL []
xref: CL:0000188
is_a: XAO:0004475 ! myocyte
relationship: part_of XAO:0000174 ! skeletal muscle
relationship: start_stage XAO:1000058 ! NF stage 46
created_by: eriksegerdell
creation_date: 2013-03-17T12:44:10Z

[Term]
id: XAO:0004477
name: smooth muscle myocyte
namespace: xenopus_anatomy
def: "A myocyte of the smooth muscle." [XAO:curators]
synonym: "smooth muscle cell" RELATED []
synonym: "smooth muscle cells" RELATED PLURAL []
synonym: "smooth muscle myocytes" RELATED PLURAL []
xref: CL:0000192
is_a: XAO:0004475 ! myocyte
relationship: part_of XAO:0000175 ! smooth muscle
created_by: eriksegerdell
creation_date: 2013-03-17T12:44:35Z

[Term]
id: XAO:0004478
name: forelimb digit 2
namespace: xenopus_anatomy
def: "The most posterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "fore digit 2" EXACT []
synonym: "manual digit 2" EXACT []
is_a: XAO:0003036 ! forelimb digit
created_by: eriksegerdell
creation_date: 2013-03-17T13:50:37Z

[Term]
id: XAO:0004479
name: forelimb digit 3
namespace: xenopus_anatomy
def: "The second most posterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "fore digit 3" EXACT []
synonym: "manual digit 3" EXACT []
is_a: XAO:0003036 ! forelimb digit
created_by: eriksegerdell
creation_date: 2013-03-17T13:50:40Z

[Term]
id: XAO:0004480
name: forelimb digit 4
namespace: xenopus_anatomy
def: "The second most anterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ]
synonym: "fore digit 4" EXACT []
synonym: "manual digit 4" EXACT []
is_a: XAO:0003036 ! forelimb digit
created_by: eriksegerdell
creation_date: 2013-03-17T13:50:49Z

[Term]
id: XAO:0004481
name: forelimb digit 5
namespace: xenopus_anatomy
def: "The most anterior digit of a forelimb, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ]
synonym: "fore digit 5" EXACT []
synonym: "manual digit 5" EXACT []
is_a: XAO:0003036 ! forelimb digit
created_by: eriksegerdell
creation_date: 2013-03-17T13:50:51Z

[Term]
id: XAO:0004482
name: epicardial precursor cell
namespace: xenopus_anatomy
def: "Neural crest-derived cell type that gives rise to the epicardium." [XAO:curators]
synonym: "epicardial precursor cells" RELATED PLURAL []
synonym: "pro-epicardial organ" RELATED []
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0000064 ! heart
relationship: part_of XAO:0005062 ! proepicardium
relationship: start_stage XAO:1000025 ! NF stage 15
created_by: eriksegerdell
creation_date: 2013-04-10T12:31:30Z

[Term]
id: XAO:0004483
name: retinal stem cell
namespace: xenopus_anatomy
def: "Cell that is present in the stem cell region of the retinal ciliary marginal zone." [XAO:CJZ]
synonym: "retinal stem cells" RELATED PLURAL []
is_a: XAO:0003054 ! stem cell
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004387 ! retinal stem cell region
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2013-04-10T12:52:47Z

[Term]
id: XAO:0004484
name: retinal progenitor cell
namespace: xenopus_anatomy
def: "Cell that is present in the progenitor cell region of the retinal ciliary marginal zone." [XAO:CJZ]
synonym: "retinal progenitor cells" RELATED PLURAL []
is_a: XAO:0005033 ! progenitor cell
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004388 ! retinal progenitor cell region
relationship: start_stage XAO:1000049 ! NF stage 35 and 36
created_by: eriksegerdell
creation_date: 2013-04-10T12:57:10Z

[Term]
id: XAO:0004485
name: neuroendocrine cell
namespace: xenopus_anatomy
def: "An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals." [CL:0000165]
synonym: "neuroendocrine cells" RELATED PLURAL []
xref: CL:0000165
is_a: XAO:0003247 ! endocrine cell
created_by: eriksegerdell
creation_date: 2013-04-10T13:03:39Z

[Term]
id: XAO:0004486
name: organ part
namespace: xenopus_anatomy
def: "Anatomical structure that has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement." [UBERON:0000064]
xref: UBERON:0000064
is_a: XAO:0003000 ! anatomical structure
relationship: start_stage XAO:1000037 ! NF stage 21
created_by: eriksegerdell
creation_date: 2013-04-10T13:51:44Z

[Term]
id: XAO:0004487
name: epiphysis
namespace: xenopus_anatomy
def: "Organ part consisting of the rounded end of a long bone (at its joint with adjacent bone), which in Xenopus are the tibia-fibula and femur of the hindlimb, and the radio-ulna and humerus of the forelimb." [XAO:CJZ]
is_a: XAO:0004486 ! organ part
relationship: part_of XAO:0003209 ! radio-ulna
relationship: part_of XAO:0003210 ! humerus
relationship: part_of XAO:0003213 ! tibia-fibula
relationship: part_of XAO:0003214 ! femur
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2013-04-10T13:54:10Z

[Term]
id: XAO:0004488
name: diaphysis
namespace: xenopus_anatomy
def: "Organ part consisting of the main section or midsection of a long bone, which in Xenopus are the tibia-fibula and femur of the hindlimb, and the radio-ulna and humerus of the forelimb." [XAO:CJZ]
is_a: XAO:0004486 ! organ part
relationship: part_of XAO:0003209 ! radio-ulna
relationship: part_of XAO:0003210 ! humerus
relationship: part_of XAO:0003213 ! tibia-fibula
relationship: part_of XAO:0003214 ! femur
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2013-04-10T14:00:23Z

[Term]
id: XAO:0004489
name: spike
namespace: xenopus_anatomy
def: "A cone-shaped hypomorphic structure consisting of a single continuous cartilage, typical of a regenerated forelimb or hindlimb when amputated after a specific developmental stage." [XAO:CJZ]
is_a: XAO:0004059 ! regenerating tissue
relationship: part_of XAO:0004311 ! regenerating limb
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2013-04-10T14:06:57Z

[Term]
id: XAO:0004490
name: forelimb bud tip
namespace: xenopus_anatomy
def: "The apical region of a developing forelimb bud which will form the autopod segment of the forelimb." [XAO:CJZ]
synonym: "presumptive forelimb autopodium" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0003065 ! forelimb bud
relationship: start_stage XAO:1000060 ! NF stage 48
created_by: eriksegerdell
creation_date: 2013-04-10T15:11:00Z

[Term]
id: XAO:0004491
name: hindlimb bud tip
namespace: xenopus_anatomy
def: "The apical region of a developing hindlimb bud which will form the autopod segment of the hindlimb." [XAO:CJZ]
synonym: "presumptive hindlimb autopodium" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000067 ! NF stage 55
relationship: part_of XAO:0003066 ! hindlimb bud
relationship: start_stage XAO:1000060 ! NF stage 48
created_by: eriksegerdell
creation_date: 2013-04-10T15:23:29Z

[Term]
id: XAO:0004492
name: cleavage furrow
namespace: xenopus_anatomy
def: "The physical groove that forms between cells at the first cell division. One-celled oocytes (NF stage 1) undergo cytoplasmic reorganization driven by sperm entry in the animal pole, where the cleavage furrow initiates, and it moves circumferentially along a line of longitude as well as progressing inwards through the cytoplasm, ultimately dividing the fertilized oocyte into two cells of equal size, defining NF stage 2." [PMID:11891298, PMID:16371595, XAO:CJZ]
is_a: XAO:0003042 ! embryonic structure
relationship: end_stage XAO:1000001 ! NF stage 1
relationship: start_stage XAO:1000092 ! mature egg stage
created_by: eriksegerdell
creation_date: 2013-04-10T15:39:26Z

[Term]
id: XAO:0004493
name: pelvic girdle primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the pelvic girdle." [XAO:EJS]
is_a: XAO:0003037 ! multi-tissue structure
relationship: end_stage XAO:1000066 ! NF stage 54
relationship: start_stage XAO:1000065 ! NF stage 53
created_by: eriksegerdell
creation_date: 2013-04-10T18:41:04Z

[Term]
id: XAO:0004494
name: iliac process
namespace: xenopus_anatomy
def: "A prominent, slender, rod-like projection of the iliac bone located close to the acetabiulum and directed posteriorly." [XAO:CJZ]
is_a: XAO:0004020 ! process
relationship: develops_from XAO:0004495 ! iliac process primordium
relationship: part_of XAO:0004496 ! ilium
relationship: start_stage XAO:1000066 ! NF stage 54
created_by: eriksegerdell
creation_date: 2013-04-10T18:45:25Z

[Term]
id: XAO:0004495
name: iliac process primordium
namespace: xenopus_anatomy
def: "The presumptive cells of the iliac process." [XAO:EJS]
is_a: XAO:0003037 ! multi-tissue structure
relationship: end_stage XAO:1000065 ! NF stage 53
relationship: start_stage XAO:1000065 ! NF stage 53
created_by: eriksegerdell
creation_date: 2013-04-10T18:49:21Z

[Term]
id: XAO:0004496
name: ilium
namespace: xenopus_anatomy
def: "Either of the paired bones that are the dorsal-most and largest bones of the pelvic girdle. They begin to connect to the sacral vertebra (9th vertebra) at NF stage 59." [XAO:CJZ]
synonym: "ilia" RELATED PLURAL []
synonym: "iliac bone" EXACT []
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003064 ! pelvic girdle
relationship: start_stage XAO:1000066 ! NF stage 54
created_by: eriksegerdell
creation_date: 2013-04-10T18:56:57Z

[Term]
id: XAO:0004497
name: ischium
namespace: xenopus_anatomy
def: "Any of the posterior and smaller bones of the pelvic girdle. The ischia appear at NF stage 53, grow toward each other at NF stage 55, fusing and beginning to ossify by NF stage 58/59." [XAO:CJZ]
synonym: "ischia" RELATED PLURAL []
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003064 ! pelvic girdle
relationship: start_stage XAO:1000066 ! NF stage 54
created_by: eriksegerdell
creation_date: 2013-04-10T19:03:50Z

[Term]
id: XAO:0004498
name: pubis
namespace: xenopus_anatomy
def: "The ventral and anterior of the three principal bones composing the pelvic girdle. The pubes fuse with the ilia at NF stage 53, and touch each other at NF stage 62. Full contact of the medial surfaces occurs at NF stage 63 when ossification also begins. Ossification continues through metamorphosis." [PMID:15679868, XAO:CJZ]
synonym: "pubes" RELATED PLURAL []
is_a: XAO:0004018 ! endochondral bone
relationship: part_of XAO:0003064 ! pelvic girdle
relationship: start_stage XAO:1000065 ! NF stage 53
created_by: eriksegerdell
creation_date: 2013-04-10T19:18:02Z

[Term]
id: XAO:0004499
name: postsacral vertebra
namespace: xenopus_anatomy
def: "Vertebra posterior to the sacral vertebra. The 4 postsacral vertebrae fuse and ossify (NF stage 66) to form the urostyle." [XAO:CJZ]
synonym: "postsacral vertebrae" RELATED PLURAL []
is_a: XAO:0004019 ! vertebra
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: start_stage XAO:1000060 ! NF stage 48
created_by: eriksegerdell
creation_date: 2013-04-10T19:27:34Z

[Term]
id: XAO:0004500
name: rib
namespace: xenopus_anatomy
def: "Any of the bony lateral projections from the presacral veterebrae of the anterior trunk region, enabling the lungs to expand and thus facilitate breathing by expanding the chest cavity. They serve to protect the lungs, heart, and other internal organs of the thorax." [http://en.wikipedia.org/wiki/Rib]
synonym: "ribs" RELATED PLURAL []
synonym: "vertebral rib" EXACT []
is_a: XAO:0004020 ! process
relationship: part_of XAO:0004019 ! vertebra
relationship: start_stage XAO:1000064 ! NF stage 52
created_by: eriksegerdell
creation_date: 2013-04-10T19:32:29Z

[Term]
id: XAO:0004501
name: apoptotic cell
namespace: xenopus_anatomy
def: "A cell that is in the process of programmed cell death. The process is characterized by morphological changes (e.g. blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation) ending in cell death." [http://en.wikipedia.org/wiki/Apoptosis]
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2013-04-10T19:46:34Z

[Term]
id: XAO:0004502
name: mitotic cell
namespace: xenopus_anatomy
def: "A cell that is in the process of replication, and is idenitifable by chromosomal replication." [XAO:curators]
is_a: XAO:0003012 ! cell
relationship: start_stage XAO:1000001 ! NF stage 1
created_by: eriksegerdell
creation_date: 2013-04-10T19:50:41Z

[Term]
id: XAO:0004503
name: periosteum
namespace: xenopus_anatomy
def: "A membrane that lines the outer surface of all bones, except at the joints of long bones. It consists of dense irregular connective tissue, and is divided into an outer fibrous layer and inner osteogenic layer. The fibrous layer contains fibroblasts, while the osteogenic layer contains progenitor cells that develop into osteoblasts, which are essential to the healing process." [http://en.wikipedia.org/wiki/Periosteum]
is_a: XAO:0001017 ! connective tissue
relationship: develops_from XAO:0004049 ! perichondrium
relationship: part_of XAO:0000169 ! bone tissue
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2013-04-10T19:57:52Z

[Term]
id: XAO:0004504
name: periosteum (sensu fibrous layer)
namespace: xenopus_anatomy
def: "The outer layer of the periosteum, containing acellular connective tissue and fibroblasts." [http://en.wikipedia.org/wiki/Periosteum]
is_a: XAO:0001017 ! connective tissue
relationship: develops_from XAO:0004049 ! perichondrium
relationship: part_of XAO:0004503 ! periosteum
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2013-04-10T20:03:11Z

[Term]
id: XAO:0004505
name: periosteum (sensu osteogenic layer)
namespace: xenopus_anatomy
def: "The inner layer of the periosteum, containing osteoblasts." [http://en.wikipedia.org/wiki/Periosteum]
is_a: XAO:0001017 ! connective tissue
relationship: develops_from XAO:0004049 ! perichondrium
relationship: part_of XAO:0004503 ! periosteum
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2013-04-10T20:03:49Z

[Term]
id: XAO:0004506
name: interdigital webbing
namespace: xenopus_anatomy
def: "The tissue or tissues between the digits of the forelimb and the hindlimb." [XAO:curators]
synonym: "webbing" RELATED []
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004265 ! autopod
relationship: part_of XAO:0004316 ! interdigital region
relationship: start_stage XAO:1000067 ! NF stage 55
created_by: eriksegerdell
creation_date: 2013-04-10T20:14:47Z

[Term]
id: XAO:0004507
name: osteoblast
namespace: xenopus_anatomy
def: "Skeletogenic cell that secretes osteoid, is capable of producing mineralized matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell." [CL:0000062]
synonym: "bone cell" RELATED []
xref: CL:0000062
is_a: XAO:0003012 ! cell
relationship: part_of XAO:0004035 ! osteoid
relationship: start_stage XAO:1000057 ! NF stage 45
created_by: eriksegerdell
creation_date: 2013-04-10T20:18:46Z

[Term]
id: XAO:0004508
name: mandibular mesenchyme
namespace: xenopus_anatomy
def: "Mesenchyme that is part of a mandibular component." [UBERON:0009584]
is_a: XAO:0003046 ! mesenchyme
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004279 ! cranial skeleton
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2013-04-10T22:47:54Z

[Term]
id: XAO:0004509
name: dorsal lateral plate mesoderm
namespace: xenopus_anatomy
def: "Layer of lateral plate mesoderm that forms the body wall lining and dermis." [http://en.wikipedia.org/wiki/Lateral_plate_mesoderm]
synonym: "DLPM" EXACT []
is_a: XAO:0003042 ! embryonic structure
relationship: part_of XAO:0000311 ! lateral plate mesoderm
relationship: start_stage XAO:1000033 ! NF stage 12.5
created_by: eriksegerdell
creation_date: 2013-04-10T23:01:12Z

[Term]
id: XAO:0004510
name: melanoblast
namespace: xenopus_anatomy
def: "Type of precursor cell from which melanophores develop." [XAO:CJZ]
xref: CL:0000541
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003012 ! cell
relationship: develops_from XAO:0000048 ! neural crest
relationship: end_stage XAO:1000047 ! NF stage 32
relationship: start_stage XAO:1000042 ! NF stage 26
created_by: eriksegerdell
creation_date: 2013-04-10T23:08:51Z

[Term]
id: XAO:0004511
name: hindgut primordium
namespace: xenopus_anatomy
def: "The endoderm cells that are fated to become the hindgut." [XAO:CJZ]
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000295 ! central endoderm
relationship: end_stage XAO:1000035 ! NF stage 19
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000026 ! NF stage 16
created_by: eriksegerdell
creation_date: 2013-04-10T23:24:26Z

[Term]
id: XAO:0004512
name: midgut primordium
namespace: xenopus_anatomy
def: "The endoderm cells that are fated to become the midgut." [XAO:CJZ]
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000295 ! central endoderm
relationship: end_stage XAO:1000035 ! NF stage 19
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000026 ! NF stage 16
created_by: eriksegerdell
creation_date: 2013-04-10T23:31:07Z

[Term]
id: XAO:0004513
name: foregut endoderm
namespace: xenopus_anatomy
def: "The endoderm cells that are fated to become the foregut." [XAO:CJZ]
synonym: "foregut primordium" RELATED []
is_a: XAO:0003043 ! primordium
relationship: develops_from XAO:0000295 ! central endoderm
relationship: end_stage XAO:1000051 ! NF stage 39
relationship: part_of XAO:0000090 ! endoderm
relationship: start_stage XAO:1000024 ! NF stage 14
created_by: eriksegerdell
creation_date: 2013-04-10T23:32:46Z

[Term]
id: XAO:0004514
name: anterior tectum
namespace: xenopus_anatomy
def: "The anterior part of the optic tectum." [XAO:EJS]
synonym: "pre-tectum" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0003226 ! optic tectum
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2013-04-10T23:41:35Z

[Term]
id: XAO:0004515
name: posterior tectum
namespace: xenopus_anatomy
def: "The posterior part of the optic tectum." [XAO:EJS]
synonym: "pre-tectum" RELATED []
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0003226 ! optic tectum
relationship: start_stage XAO:1000052 ! NF stage 40
created_by: eriksegerdell
creation_date: 2013-04-10T23:43:45Z

[Term]
id: XAO:0004516
name: blastocoel floor
namespace: xenopus_anatomy
def: "The upper surface of the vegetal yolk mass which forms the floor for the blastocoel (cavity) of the early gastrula embryo." [XAO:curators]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000023 ! NF stage 13
relationship: part_of XAO:0000294 ! blastocoel
created_by: eriksegerdell
creation_date: 2013-04-10T23:45:26Z

[Term]
id: XAO:0004517
name: ciliated non-epidermal cell
namespace: xenopus_anatomy
def: "A ciliated cell that is not part of the epidermis." [XAO:EJS]
is_a: XAO:0005017 ! ciliated cell
created_by: eriksegerdell
creation_date: 2013-04-11T11:36:47Z

[Term]
id: XAO:0004518
name: proximal tubule
namespace: xenopus_anatomy
def: "The proximal segment of the pronephric tubule, closest to the glomus and functioning in solute resorption and waste excretion." [PMID:15223337]
synonym: "pronephric nephron" RELATED []
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004105 ! pronephric tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: eriksegerdell
creation_date: 2013-04-26T14:20:27Z

[Term]
id: XAO:0004519
name: distal tubule
namespace: xenopus_anatomy
def: "The distal segment of the pronephric tubule, functioning in water resorption, with urine passing through it into the pronephric duct." [PMID:15223337]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004105 ! pronephric tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: eriksegerdell
creation_date: 2013-04-26T14:34:59Z

[Term]
id: XAO:0004520
name: proximal tubule branch
namespace: xenopus_anatomy
def: "A distal stem cell region of the proximal tubule. There are 3 branches, with anteriodorsal, anterioventral, and posterior positions. These are sometimes referred to as proximal tubule segment 1 or PT1." [XAO:CJZ]
synonym: "proximal tubule  segment 1" RELATED []
synonym: "PT1" RELATED []
is_a: XAO:0003186 ! anatomical region
relationship: end_stage XAO:1000076 ! NF stage 64
relationship: part_of XAO:0004518 ! proximal tubule
relationship: start_stage XAO:1000045 ! NF stage 29 and 30
created_by: eriksegerdell
creation_date: 2013-04-26T14:48:46Z

[Term]
id: XAO:0004521
name: coelom
namespace: xenopus_anatomy
def: "A fluid-filled cavity formed within the mesoderm of the embryo." [http://en.wikipedia.org/wiki/Coelom]
synonym: "body cavity" RELATED []
is_a: XAO:0003190 ! anatomical space
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000113 ! embryo
relationship: part_of XAO:0003025 ! trunk
relationship: start_stage XAO:1000035 ! NF stage 19
created_by: eriksegerdell
creation_date: 2013-04-26T15:36:18Z

[Term]
id: XAO:0004522
name: premigratory neural crest cell
namespace: xenopus_anatomy
def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration." [CL:0007004]
synonym: "premigratory neural crest cells" RELATED PLURAL []
xref: CL:0007004
is_a: XAO:0003012 ! cell
relationship: end_stage XAO:1000046 ! NF stage 31
relationship: part_of XAO:0000048 ! neural crest
relationship: start_stage XAO:1000023 ! NF stage 13
created_by: eriksegerdell
creation_date: 2013-05-27T16:31:38Z

[Term]
id: XAO:0004523
name: enteric neuron
namespace: xenopus_anatomy
def: "Any of the neurons specific to the gastrointestinal system. Enteric neurons are embedded the lining of the esophagus, stomach, small and large intestines and the cloaca." [https://en.wikipedia.org/wiki/Enteric_nervous_system]
xref: CL:0007011
is_a: XAO:0003023 ! neuron
relationship: develops_from XAO:0000048 ! neural crest
relationship: part_of XAO:0000104 ! hindgut
relationship: part_of XAO:0000130 ! small intestine
relationship: part_of XAO:0000131 ! large intestine
relationship: part_of XAO:0000244 ! cloaca
relationship: part_of XAO:0005195 ! enteric nervous system
relationship: start_stage XAO:1000036 ! NF stage 20
created_by: eriksegerdell
creation_date: 2013-05-27T16:58:52Z

[Term]
id: XAO:0004524
name: pharyngeal mesenchyme
namespace: xenopus_anatomy
def: "The undifferentiated, loose connective tissue of the pharyngeal region, that is derived mostly from mesoderm, and also contains ectodermally derived neural crest cells." [XAO:CJZ]
is_a: XAO:0003046 ! mesenchyme
relationship: part_of XAO:0004261 ! pharyngeal region
relationship: start_stage XAO:1000036 ! NF stage 20

[Term]
id: XAO:0004525
name: medium cavity
namespace: xenopus_anatomy
def: "Water-filled cavity in the adult frog that is apposed to an olfactory epithelium for detection of aqueous odorants." [XAO:KAB]
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000078 ! NF stage 66

[Term]
id: XAO:0004526
name: principal cavity
namespace: xenopus_anatomy
def: "Air-filled cavity in the adult frog apposed to an olfactory epithelium for detection of airborne odorants." [XAO:KAB]
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0003196 ! olfactory system
relationship: start_stage XAO:1000078 ! NF stage 66

[Term]
id: XAO:0004527
name: olfactory sensory neuron
namespace: xenopus_anatomy
def: "Sensory neuron responsible for detection of odorants." [XAO:KAB]
synonym: "olfactory receptor neuron" EXACT []
synonym: "ORN" EXACT []
synonym: "OSN" EXACT []
is_a: XAO:0003023 ! neuron
relationship: part_of XAO:0005024 ! olfactory epithelium
relationship: start_stage XAO:1000039 ! NF stage 23

[Term]
id: XAO:0004528
name: tail somite 18
namespace: xenopus_anatomy
def: "The 16th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS]
synonym: "somite 18" EXACT []
synonym: "trunk somite 18" EXACT []
is_a: XAO:0003143 ! tail somite
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0004529
name: uveal tract
namespace: xenopus_anatomy
def: "Portion of tissue in an eye consisting of the iris, ciliary body, and choroid." [UBERON:0001768]
synonym: "uvea" EXACT []
xref: UBERON:0001768
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000056 ! NF stage 44

[Term]
id: XAO:0004530
name: accessory olfactory bulb
namespace: xenopus_anatomy
def: "The forebrain region that coordinates sensory signaling arising from the vomeronasal organ; it is located on the dorsal-posterior portion of the main olfactory bulb, and the axons that leave the accessory olfactory bulb project to targets in the amygdala and hypothalamus." [UBERON:0004069]
synonym: "anterior olfactory bulb" RELATED []
xref: UBERON:0004069
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004180 ! olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004531
name: amygdala
namespace: xenopus_anatomy
def: "An almond-shaped set of neurons in the medial temporal lobe of the brain that is involved in the linkage of environmental information with social behavior and action selection." [GO:0021764, PMID:24005304]
synonym: "Amyg" EXACT []
synonym: "corpus amygdaloideum" RELATED []
xref: UBERON:0001876
is_a: XAO:0003160 ! anatomical cluster
relationship: develops_from XAO:0004258 ! subpallium
relationship: develops_from XAO:0004563 ! lateral pallium
relationship: develops_from XAO:0004594 ! ventral pallium
relationship: part_of XAO:0004539 ! basal forebrain
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004532
name: anterior amygdala
namespace: xenopus_anatomy
def: "A nucleus comprising the anterior aspect of the amygdala, adjacent to the basal forebrain, and involved in receiving olfactory information." [ISBN:0123815339]
xref: UBERON:0002890
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004531 ! amygdala
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004533
name: anterior commissure
namespace: xenopus_anatomy
def: "A forebrain white matter structure consisting of a large fiber bundle, connecting the two cerebral hemispheres across the middle line." [XAO:KAB]
synonym: "AC" EXACT []
xref: UBERON:0000935
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000012 ! telencephalon
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004534
name: anterior entopeduncular nucleus
namespace: xenopus_anatomy
def: "Nucleus situated in the pallidum that provides auditory input to the torus semicircularis." [PMID:11536185]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004578 ! pallidum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004535
name: ventral funiculus
namespace: xenopus_anatomy
def: "Region of spinal cord white matter lying on either side between the ventral median fissure and the ventral roots of the spinal nerves." [http://medical-dictionary.thefreedictionary.com/ventral+funiculus]
synonym: "anterior funiculus" RELATED []
xref: UBERON:0002180
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004536
name: anterior thalamic nucleus
namespace: xenopus_anatomy
def: "Nucleus situated in the thalamus that is associated with the limbic system and is implicated in learning and episodic memory." [http://en.wikipedia.org/wiki/Anterior_nuclei_of_thalamus]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004306 ! thalamus

[Term]
id: XAO:0004537
name: anterodorsal tegmental nucleus
namespace: xenopus_anatomy
def: "Nucleus located anterodorsally in the midbrain tegmentum." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004271 ! midbrain tegmentum

[Term]
id: XAO:0004538
name: anteroventral tegmental nucleus
namespace: xenopus_anatomy
def: "Nucleus located anteroventrally in the midbrain tegmentum." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004271 ! midbrain tegmentum

[Term]
id: XAO:0004539
name: basal forebrain
namespace: xenopus_anatomy
def: "A group of structures that lie in the ventralmost parts of the forebrain and are formed by the derivatives of the subpallium." [XAO:KAB]
synonym: "ventral telencephalon" RELATED []
xref: UBERON:0002743
is_a: XAO:0003037 ! multi-tissue structure
relationship: develops_from XAO:0004258 ! subpallium
relationship: part_of XAO:0000012 ! telencephalon
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004540
name: basal ganglion
namespace: xenopus_anatomy
def: "Composite structure derived principally from the subpallium and containing numerous ganglia of the ventral telencephalon." [XAO:KAB]
synonym: "basal ganglia" RELATED PLURAL []
synonym: "basal ganglia nuclei" RELATED []
synonym: "basal nuclei" RELATED []
xref: UBERON:0010011
is_a: XAO:0003160 ! anatomical cluster
relationship: develops_from XAO:0004258 ! subpallium
relationship: part_of XAO:0004539 ! basal forebrain
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004541
name: bed nucleus of the stria terminalis
namespace: xenopus_anatomy
def: "A brain structure in the forebrain wrapped around the stria terminalis. Its largest extent can be found around the crossing of the anterior commissure." [UBERON:0001880]
synonym: "bed nucleus striae terminalis" EXACT []
synonym: "BST" EXACT []
xref: UBERON:0001880
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004539 ! basal forebrain
relationship: start_stage XAO:1000061 ! NF stage 49

[Term]
id: XAO:0004542
name: central amygdala
namespace: xenopus_anatomy
def: "A nucleus comprising the central aspect of the amygdala, identified as a target for ascending auditory information from the central thalamic nucleus and as a major afferent to the vocal pattern generator of the hindbrain." [PMID:24005304]
synonym: "CeA" EXACT []
xref: UBERON:0002883
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004531 ! amygdala
relationship: part_of XAO:0004587 ! striatum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004543
name: central canal
namespace: xenopus_anatomy
def: "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [UBERON:0002291]
xref: UBERON:0002291
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004544
name: central nucleus of the thalamus
namespace: xenopus_anatomy
def: "Nucleus that is located centrally in the thalamus." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004306 ! thalamus

[Term]
id: XAO:0004545
name: dorsal column nucleus
namespace: xenopus_anatomy
def: "A nucleus that is situated in the brainstem." [http://en.wikipedia.org/wiki/Dorsal_column_nuclei]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0003100 ! medulla oblongata

[Term]
id: XAO:0004546
name: dorsal habenular nucleus
namespace: xenopus_anatomy
def: "Cell mass in the caudal and dorsal aspect of the dorsal thalamus adjoining the pineal gland." [XAO:KAB]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004556 ! habenula
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0004547
name: dorsal pallidum
namespace: xenopus_anatomy
def: "The predominant portion of the globus pallidus in the striatopallidal system, which is defined by connectivity and neurochemical staining. It is distinguished from the ventral pallidum by a boundary that is partially defined by the anterior commissure." [UBERON:0006516]
xref: UBERON:0006516
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004578 ! pallidum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004548
name: dorsal pallium
namespace: xenopus_anatomy
def: "Subdivision of thepallium that is located dorsally." [UBERON:0014740]
synonym: "isocortex" RELATED []
xref: UBERON:0014740
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004302 ! pallium
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004549
name: dorsal septum
namespace: xenopus_anatomy
def: "A set of septal nuclei comprising the dorsal aspect of the forebrain septum." [XAO:KAB]
synonym: "Sd" EXACT []
synonym: "septum dorsalis" EXACT []
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004585 ! septum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004551
name: external plexiform layer of the olfactory bulb
namespace: xenopus_anatomy
def: "Cytoarchitectural part of the olfactory bulb, lying superior to the mitral cell layer and inferior to the glomerular layer. The EPL is mostly neuropil composed almost entirely of mitral and tulfted cell dendrites and granule cell dendrites and their synaptic inputs." [UBERON:0005376]
xref: UBERON:0005376
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004180 ! olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004552
name: glomerular layer of the olfactory bulb
namespace: xenopus_anatomy
def: "Superficial layer of the olfactory bulb, composed of spherical glomeruli, where input from olfactory receptor neurons is first organized and processed." [PMID:16765614]
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004180 ! olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004553
name: granule cell
namespace: xenopus_anatomy
def: "Type of neuron characterized by having very small cell bodies. These cells are found within the granular layers of the cerebellum and the olfactory bulb." [http://en.wikipedia.org/wiki/Granule_cell]
xref: CL:0000120
is_a: XAO:0004267 ! interneuron
relationship: part_of XAO:0004554 ! granule cell layer of the cerebellum
relationship: part_of XAO:0004555 ! granule cell layer of the olfactory bulb
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004554
name: granule cell layer of the cerebellum
namespace: xenopus_anatomy
def: "The innermost layer of the cerebellar cortex, containing densely packed small neurons, mostly granule cells." [UBERON:0002956]
xref: UBERON:0002956
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0003098 ! cerebellum
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004555
name: granule cell layer of the olfactory bulb
namespace: xenopus_anatomy
def: "A layer of the olfactory bulb interior to the mitral cell layer, consisting of inhibitory interneurons." [XAO:KAB]
synonym: "internal granular layer" RELATED []
xref: UBERON:0005378
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004180 ! olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004556
name: habenula
namespace: xenopus_anatomy
def: "Region of the thalamus adjoining the pineal gland." [XAO:KAB]
synonym: "Hb" EXACT []
xref: UBERON:0001904
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004390 ! dorsal thalamus
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0004557
name: isthmic nucleus
namespace: xenopus_anatomy
def: "Nucleus that is a prominant part of the visual system, receiving input from the ipsilateral tectum and sending output to both tecta." [PMID:3497362]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0000016 ! midbrain-hindbrain boundary

[Term]
id: XAO:0004558
name: lateral amygdala
namespace: xenopus_anatomy
def: "A nucleus comprising the lateral aspect of the amygdala, implicated in fear conditioning." [http://en.wikipedia.org/wiki/Amygdala]
synonym: "LA" EXACT []
xref: UBERON:0002886
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004531 ! amygdala
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004559
name: lateral forebrain bundle
namespace: xenopus_anatomy
def: "A fiber system that is formed by pallial and subpallial components that join in the caudal telencephalon. It proceeds caudally, piercing the optic tract, to the ventral part of the hypothalamus." [ISBN:3540560130]
synonym: "LFB" EXACT []
xref: UBERON:2007012
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000011 ! forebrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004560
name: lateral funiculus
namespace: xenopus_anatomy
def: "Region of spinal cord white matter that is both ventral to the dorsal root and dorsal to the ventral root." [XAO:KAB]
xref: UBERON:0002179
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004562
name: lateral hypothalamic nucleus
namespace: xenopus_anatomy
def: "Diencephalic nucleus that is the lateral part of the ventral hypothalamic zone." [XAO:EJS, ZFA:0000227]
xref: UBERON:0001937
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004070 ! hypothalamus
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004563
name: lateral pallium
namespace: xenopus_anatomy
def: "Subdivision of the pallium that is located laterally." [UBERON:0014741]
synonym: "olfactory cortex" RELATED []
xref: UBERON:0014741
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004302 ! pallium
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004564
name: lateral septum
namespace: xenopus_anatomy
def: "A set of septal nuclei comprising the lateral aspect of the forebrain septum." [XAO:KAB]
synonym: "septum lateralis" EXACT []
synonym: "Sl" EXACT []
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004585 ! septum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004565
name: laterodorsal tegmental nucleus
namespace: xenopus_anatomy
def: "A nucleus situated in the brainstem, spanning the midbrain tegmentum and the pontine tegmentum." [UBERON:0002267]
xref: UBERON:0002267
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004271 ! midbrain tegmentum

[Term]
id: XAO:0004566
name: locus coeruleus
namespace: xenopus_anatomy
def: "Nucleus within the brainstem that is the principal site for brain synthesis of norepinephrine." [XAO:KAB]
synonym: "locus caeruleus" EXACT []
synonym: "locus ceruleus" EXACT []
xref: UBERON:0002148
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0000015 ! hindbrain

[Term]
id: XAO:0004567
name: magnocellular preoptic nucleus
namespace: xenopus_anatomy
def: "A nucleus situated in the preoptic area that contains large neurosecretory neurons." [ISBN:0080877982, ISBN:3540560130]
xref: UBERON:2000248
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004583 ! preoptic area
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0004568
name: medial amygdala
namespace: xenopus_anatomy
def: "A nucleus comprising the medial aspect of the amygdala, involved in receiving olfactory information." [http://en.wikipedia.org/wiki/Amygdala]
synonym: "MeA" EXACT []
xref: UBERON:0002892
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004531 ! amygdala
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004570
name: medial pallium
namespace: xenopus_anatomy
def: "Subdivision of the pallium that is located in the medial position." [UBERON:0014738]
synonym: "hippocampus" RELATED []
synonym: "MP" EXACT []
xref: UBERON:0014738
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004302 ! pallium
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004571
name: medial septum
namespace: xenopus_anatomy
def: "A set of septal nuclei comprising the medial aspect of the forebrain septum." [XAO:KAB]
synonym: "septum medialis" EXACT []
synonym: "Sm" EXACT []
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004585 ! septum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004573
name: mitral cell
namespace: xenopus_anatomy
def: "Large glutaminergic nerve cell whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex." [MP:0009954]
xref: CL:1001502
is_a: XAO:0003023 ! neuron
relationship: part_of XAO:0004574 ! mitral cell layer of the olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004574
name: mitral cell layer of the olfactory bulb
namespace: xenopus_anatomy
def: "Layer composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer." [UBERON:0004186]
xref: UBERON:0004186
is_a: XAO:0003040 ! tissue
relationship: part_of XAO:0004180 ! olfactory bulb
relationship: start_stage XAO:1000042 ! NF stage 26

[Term]
id: XAO:0004575
name: nucleus accumbens
namespace: xenopus_anatomy
def: "A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen." [UBERON:0001882]
synonym: "Acc" EXACT []
synonym: "accumbens nucleus" EXACT []
synonym: "nucleus accumbens septi" RELATED []
xref: UBERON:0001882
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004587 ! striatum
relationship: start_stage XAO:1000065 ! NF stage 53

[Term]
id: XAO:0004576
name: nucleus of the diagonal band
namespace: xenopus_anatomy
def: "A brain structure that is part of the septal nuclear complex and is connected with the hippocampus, hypothalamus, and amygdala." [UBERON:0001879]
synonym: "diagonal band" RELATED []
synonym: "diagonal band of Broca" RELATED []
xref: UBERON:0001879
is_a: XAO:0004609 ! neural nucleus
relationship: develops_from XAO:0004258 ! subpallium
relationship: part_of XAO:0004539 ! basal forebrain
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004578
name: pallidum
namespace: xenopus_anatomy
def: "Major component of the basal ganglia that is part of the telencephalon and has close functional ties with the subthalamus." [http://en.wikipedia.org/wiki/Globus_pallidus]
synonym: "globus pallidus" EXACT []
synonym: "Pa" EXACT []
synonym: "paleostriatum" RELATED []
synonym: "pallidal nuclei" RELATED []
xref: UBERON:0001875
is_a: XAO:0003160 ! anatomical cluster
relationship: develops_from XAO:0004259 ! medial ganglionic eminence
relationship: part_of XAO:0004540 ! basal ganglion
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004579
name: posterior commissure
namespace: xenopus_anatomy
def: "Diencephalic tract that is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei." [XAO:EJS, ZFA:0000320]
xref: UBERON:0000936
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000014 ! midbrain
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004580
name: dorsal funiculus
namespace: xenopus_anatomy
def: "Region of spinal cord white matter that is dorsal and medial to the dorsal root." [XAO:KAB]
synonym: "posterior funiculus" RELATED []
xref: UBERON:0002258
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000020 ! spinal cord
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004581
name: posterodorsal tegmental nucleus
namespace: xenopus_anatomy
def: "Nucleus located posterodorsally in the midbrain tegmentum." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004271 ! midbrain tegmentum

[Term]
id: XAO:0004582
name: posteroventral tegmental nucleus
namespace: xenopus_anatomy
def: "Nucleus located posteroventrally in the midbrain tegmentum." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004271 ! midbrain tegmentum

[Term]
id: XAO:0004583
name: preoptic area
namespace: xenopus_anatomy
def: "Area of the forebrain anterior to the posterior tuberculum and the hypothalamus and ventral to the ventral thalamus." [UBERON:0001928]
synonym: "anterior preoptic area" RELATED []
synonym: "PO" EXACT []
synonym: "preoptic nuclei" RELATED []
synonym: "preoptic region" RELATED []
xref: UBERON:0001928
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004230 ! anterior hypothalamus
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0004584
name: raphe nucleus
namespace: xenopus_anatomy
def: "A cluster of nuclei found in the brain stem, the main function of which is to release serotonin to the rest of the brain." [http://en.wikipedia.org/wiki/Raphe_nuclei]
xref: UBERON:0004684
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0003100 ! medulla oblongata
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004585
name: septum
namespace: xenopus_anatomy
def: "Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum and the septal nuclei." [UBERON:0000446]
synonym: "Se" EXACT []
synonym: "septum of telencephalon" RELATED []
xref: UBERON:0000446
is_a: XAO:0003160 ! anatomical cluster
relationship: develops_from XAO:0004258 ! subpallium
relationship: part_of XAO:0004539 ! basal forebrain
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004586
name: solitary tract
namespace: xenopus_anatomy
def: "A compact fiber bundle that extends longitudinally through the posterolateral region of the medulla and is surrounded by the nucleus of the solitary tract, and descends to the upper cervical segments of the spinal cord." [UBERON:0002718]
xref: UBERON:0002718
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000020 ! spinal cord
relationship: part_of XAO:0005048 ! nucleus of the solitary tract
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004587
name: striatum
namespace: xenopus_anatomy
def: "A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati." [UBERON:0002435]
synonym: "neostriatum" RELATED []
synonym: "Str" EXACT []
synonym: "striatal nuclei" RELATED []
synonym: "striate nucleus" RELATED []
xref: UBERON:0002435
is_a: XAO:0003160 ! anatomical cluster
relationship: develops_from XAO:0004237 ! lateral ganglionic eminence
relationship: part_of XAO:0004540 ! basal ganglion
relationship: start_stage XAO:1000065 ! NF stage 53

[Term]
id: XAO:0004588
name: subcommissural organ
namespace: xenopus_anatomy
def: "A small ependymal gland of the circumventricular system, located in the dorsocaudal region of the third ventricle." [XAO:KAB]
xref: UBERON:0002139
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004303 ! pretectum
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004589
name: subthalamic nucleus
namespace: xenopus_anatomy
def: "The lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function." [UBERON:0001906]
xref: UBERON:0001906
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004304 ! prethalamus
relationship: part_of XAO:0004540 ! basal ganglion
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004590
name: torus semicircularis
namespace: xenopus_anatomy
def: "Multi-tissue structure that is part of the midbrain and develops from the alar plate. It is located dorsal to the lateral tegmentum where it extends into the medial tectal ventricle and receives ascending sensory octavolateralis input." [XAO:EJS, ZFA:0000599]
xref: UBERON:2000599
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0000014 ! midbrain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004591
name: ventral habenular nucleus
namespace: xenopus_anatomy
def: "Cell mass in the caudal and ventral aspect of the dorsal thalamus adjoining the pineal gland." [XAO:KAB]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004556 ! habenula
relationship: start_stage XAO:1000049 ! NF stage 35 and 36

[Term]
id: XAO:0004592
name: ventral hypothalamic nucleus
namespace: xenopus_anatomy
def: "Nucleus that is located ventrally in the hypothalamus." [XAO:EJS]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004070 ! hypothalamus
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004593
name: ventral pallidum
namespace: xenopus_anatomy
def: "Part of the globus pallidus consisting of the more medial of the two segments." [UBERON:0002778]
xref: UBERON:0002778
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0004578 ! pallidum
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004594
name: ventral pallium
namespace: xenopus_anatomy
def: "The pallial region located next to the pallium-subpallium boundary." [UBERON:0014913]
xref: UBERON:0014913
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004302 ! pallium
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004595
name: ventrolateral thalamic nucleus
namespace: xenopus_anatomy
def: "Nucleus situated in the thalamus that receives inputs from the basal nuclei and the function of which is to help coordinate and plan movement." [http://en.wikipedia.org/wiki/Ventral_lateral_nucleus]
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004306 ! thalamus

[Term]
id: XAO:0004596
name: ventromedial thalamic nucleus
namespace: xenopus_anatomy
def: "Nucleus situated in the thalamus to which somatosensory input is predominantly directed." [ISBN:3540560130]
xref: UBERON:2000459
is_a: XAO:0004609 ! neural nucleus
relationship: part_of XAO:0004306 ! thalamus

[Term]
id: XAO:0004597
name: neuromere
namespace: xenopus_anatomy
def: "A metameric segment of the central nervous system." [XAO:EJS, ZFA:0001328]
xref: UBERON:0004731
is_a: XAO:0003013 ! organism subdivision
relationship: end_stage XAO:1000056 ! NF stage 44
relationship: part_of XAO:0000215 ! central nervous system
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004598
name: prosomere
namespace: xenopus_anatomy
def: "A neuromere that is part of the presumptive forebrain." [UBERON:0014775]
xref: UBERON:0014775
is_a: XAO:0004597 ! neuromere
relationship: part_of XAO:0000011 ! forebrain

[Term]
id: XAO:0004599
name: prosomere 4
namespace: xenopus_anatomy
def: "The 4th segment of the developing forebrain." [XAO:EJS]
is_a: XAO:0004598 ! prosomere
relationship: part_of XAO:0000013 ! diencephalon

[Term]
id: XAO:0004600
name: prosomere 5
namespace: xenopus_anatomy
def: "The 5th segment of the developing forebrain." [XAO:EJS]
is_a: XAO:0004598 ! prosomere
relationship: part_of XAO:0000012 ! telencephalon

[Term]
id: XAO:0004601
name: prosomere 6
namespace: xenopus_anatomy
def: "The 6th segment of the developing forebrain." [XAO:EJS]
is_a: XAO:0004598 ! prosomere
relationship: part_of XAO:0000012 ! telencephalon

[Term]
id: XAO:0004602
name: brain ventricle
namespace: xenopus_anatomy
def: "One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that are lined with an epithelial ependyma, and that contain cerebral-spinal fluid. The system comprises four ventricles, the right and left lateral ventricles (one for each hemisphere), third ventricle, and fourth ventricle." [http://en.wikipedia.org/wiki/Ventricular_system, UBERON:0004086]
synonym: "ventricle" BROAD []
xref: UBERON:0004086
is_a: XAO:0003190 ! anatomical space
relationship: part_of XAO:0000010 ! brain
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004605
name: mammilary region
namespace: xenopus_anatomy
def: "A protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei." [UBERON:0002206]
synonym: "corpus mamillare" EXACT []
synonym: "MA" EXACT []
synonym: "mammillar area" RELATED []
xref: UBERON:0002206
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004236 ! posterior hypothalamus
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004606
name: tuberal region
namespace: xenopus_anatomy
def: "Structure that lies rostral to the area of the tegmentum and that is a site of dopamine-containing cells." [ISBN:0471733830]
synonym: "caudal tuberculum" RELATED []
synonym: "posterior tuberculum" RELATED []
synonym: "Tub" EXACT []
xref: UBERON:2000633
is_a: XAO:0003037 ! multi-tissue structure
relationship: part_of XAO:0004236 ! posterior hypothalamus
relationship: start_stage XAO:1000047 ! NF stage 32

[Term]
id: XAO:0004607
name: lateral ventricle
namespace: xenopus_anatomy
def: "Either of the two brain ventricles that are bilateral (left and right, one for each hemisphere)." [XAO:EJS]
is_a: XAO:0004602 ! brain ventricle

[Term]
id: XAO:0004608
name: third ventricle
namespace: xenopus_anatomy
def: "Brain ventricle formed by a median cleft in the diencephalon between the two thalami." [http://en.wikipedia.org/wiki/Third_ventricle]
synonym: "3rd ventricle" EXACT []
xref: UBERON:0002286
is_a: XAO:0004602 ! brain ventricle
relationship: part_of XAO:0000013 ! diencephalon

[Term]
id: XAO:0004609
name: neural nucleus
namespace: xenopus_anatomy
def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections." [UBERON:0000125]
synonym: "nucleus" BROAD []
xref: UBERON:0000125
is_a: XAO:0003160 ! anatomical cluster
relationship: part_of XAO:0000215 ! central nervous system
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0004610
name: left ventricle
namespace: xenopus_anatomy
def: "The lateral ventricle that is located in the left hemisphere of the brain." [XAO:EJS]
is_a: XAO:0004607 ! lateral ventricle

[Term]
id: XAO:0004611
name: right ventricle
namespace: xenopus_anatomy
def: "The lateral ventricle that is located in the right hemisphere of the brain." [XAO:EJS]
is_a: XAO:0004607 ! lateral ventricle

[Term]
id: XAO:0004612
name: secretory epithelial cell
namespace: xenopus_anatomy
def: "Type of epithelial cell that secretes a macromolecule or ion product. In many epithelia, occasional specialized secretory cells are scattered among other, non-secretory cells." [ISBN:0323036635]
synonym: "scattered secretory epithelial cell" RELATED []
is_a: BFO:0000004 ! independent continuant
is_a: XAO:0003249 ! epithelial cell
relationship: develops_from XAO:0000001 ! ectoderm

[Term]
id: XAO:0004613
name: non-cililated epidermal cell
namespace: xenopus_anatomy
def: "Epidermal cell that lacks cilia." [XAO:EJS]
synonym: "non-ciliated epidermal cells" RELATED PLURAL []
is_a: XAO:0004621 ! epidermal cell

[Term]
id: XAO:0004614
name: ciliary axoneme
namespace: xenopus_anatomy
def: "The bundle of microtubules and associated proteins that forms the core of cilia and is responsible for their movements." [GO:0005930]
synonym: "axoneme" EXACT []
xref: GO:0005930
is_a: XAO:0004290 ! cell part
relationship: part_of XAO:0005008 ! cilium
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0004615
name: basal body
namespace: xenopus_anatomy
def: "A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a cilium that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth." [GO:0005932]
synonym: "ciliary basal body" RELATED []
xref: GO:0005932
is_a: XAO:0004290 ! cell part
relationship: start_stage XAO:1000001 ! NF stage 1

[Term]
id: XAO:0004616
name: ventrolateral neural tube
namespace: xenopus_anatomy
def: "The ventrolateral regions of the neural tube, above to the floor plate region and encompassing structurally distinct interneurons (in lateral positions) and the more ventral motor neurons." [XAO:CJZ]
synonym: "ventricular zone" BROAD []
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000249 ! neural plate
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0003204 ! neural tube
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0004617
name: dorsolateral neural tube
namespace: xenopus_anatomy
def: "The dorsolateral regions of the neural tube, ventral to the roof plate region and encompassing structurally distinct sensory neurons (more dorsally) and interneurons (in lateral positions)." [XAO:CJZ]
is_a: XAO:0003042 ! embryonic structure
relationship: develops_from XAO:0000249 ! neural plate
relationship: end_stage XAO:1000044 ! NF stage 28
relationship: part_of XAO:0003204 ! neural tube
relationship: start_stage XAO:1000034 ! NF stage 18

[Term]
id: XAO:0004618
name: rostral presomitic mesoderm
namespace: xenopus_anatomy
def: "The region of presomitic mesoderm that lays immediately adjacent and posterior to the last formed somite." [XAO:CJZ]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000057 ! presomitic mesoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0004619
name: caudal presomitic mesoderm
namespace: xenopus_anatomy
def: "The most posterior region of presomitic mesoderm where somitomeres have yet to be fated." [XAO:CJZ]
is_a: XAO:0003040 ! tissue
relationship: end_stage XAO:1000059 ! NF stage 47
relationship: part_of XAO:0000057 ! presomitic mesoderm
relationship: start_stage XAO:1000023 ! NF stage 13

[Term]
id: XAO:0004620
name: neurogenic placode
namespace: xenopus_anatomy
def: "Cranial placode with neurogenic potential." [UBERON:0009955]
xref: UBERON:0009955
is_a: XAO:0000305 ! cranial placode
relationship: develops_from XAO:0004092 ! preplacodal ectoderm

[Term]
id: XAO:0004621
name: epidermal cell
namespace: xenopus_anatomy
def: "An epithelial cell that is part of the epidermis." [XAO:EJS]
xref: CL:1000396
is_a: XAO:0003249 ! epithelial cell
relationship: part_of XAO:0000028 ! epidermis
relationship: start_stage XAO:1000025 ! NF stage 15

[Term]
id: XAO:0004622
name: myotome of tail somite 18
namespace: xenopus_anatomy
def: "Compartment of tail somite 18 that is a precursor of muscle." [XAO:EJS]
synonym: "myotome of trunk somite 18" EXACT []
is_a: XAO:0000315 ! myotome
relationship: develops_from XAO:0004528 ! tail somite 18
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0004623
name: sclerotome of tail somite 18
namespace: xenopus_anatomy
def: "Compartment of tail somite 18 that is a precursor of the axial skeleton." [XAO:EJS]
synonym: "sclerotome of somite 18" EXACT []
synonym: "sclerotome of trunk somite 18" EXACT []
is_a: XAO:0000397 ! sclerotome
relationship: develops_from XAO:0004528 ! tail somite 18
relationship: start_stage XAO:1000045 ! NF stage 29 and 30

[Term]
id: XAO:0004624
name: fin vasculature
namespace: xenopus_anatomy
def: "Blood vessel that is part of the fin." [XAO:EJS]
is_a: XAO:0001011 ! blood vessel
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0000002 ! fin

[Term]
id: XAO:0004625
name: dorsal fin vasculature
namespace: xenopus_anatomy
def: "Blood vessel that is part of the dorsal fin." [XAO:EJS]
is_a: XAO:0001011 ! blood vessel
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004063 ! dorsal fin
relationship: part_of XAO:0004624 ! fin vasculature

[Term]
id: XAO:0004626
name: ventral fin vasculature
namespace: xenopus_anatomy
def: "Blood vessel that is part of the ventral fin." [XAO:EJS]
is_a: XAO:0001011 ! blood vessel
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000078 ! NF stage 66
relationship: part_of XAO:0004624 ! fin vasculature

[Term]
id: XAO:0004627
name: ventral blood island border
namespace: xenopus_anatomy
def: "Blood vessel that is part of the ventral blood island." [XAO:EJS]
synonym: "vbib" EXACT []
is_a: XAO:0001011 ! blood vessel
relationship: develops_from XAO:0000050 ! mesoderm
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: part_of XAO:0000067 ! ventral blood island

[Term]
id: XAO:0004628
name: posterior ventral blood island
namespace: xenopus_anatomy
def: "The erythroid-forming compartment of the ventral blood island." [PMID:18594023]
synonym: "pvbi" EXACT []
is_a: XAO:0003040 ! tissue
relationship: develops_from XAO:0004473 ! ventral mesoderm
relationship: end_stage XAO:1000049 ! NF stage 35 and 36
relationship: part_of XAO:0000067 ! ventral blood island
relationship: start_stage XAO:1000038 ! NF stage 22

[Term]
id: XAO:0005000
name: matrix-based tissue
namespace: xenopus_anatomy
def: "A tissue whose predominant feature is extracellular matrix that may or may not be highly hydrated or calcified." [UBERON:0007475]
xref: UBERON:0007475
is_a: XAO:0003040 ! tissue
relationship: start_stage XAO:1000020 ! NF stage 10
created_by: eriksegerdell
creation_date: 2015-04-15T18:09:42Z

[Term]
id: XAO:0005001
name: acellular bone tissue
namespace: xenopus_anatomy
def: "Mineralized