versionIRI: http://purl.obolibrary.org/obo/ontoneo/import/go_import.owl An ontology for describing the function of genes and gene products. GO subset applied to OntONeo ontology. PERSON: Fernanda Farinelli This owl file represents the necessary entities of GO that are reused in OntONeo Ontology. This file was created using Ontofox and some intermediary entities were not imported. Gene Ontology 2021-02-01 definition imported from has_alternative_id database_cross_reference has_exact_synonym has_narrow_synonym has_obo_namespace has_related_synonym in_subset GO:0019952 GO:0050876 Wikipedia:Reproduction reproductive physiological process The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. reproduction skeletal development biological_process GO:0001501 The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). skeletal system development biological_process follicular phase GO:0001541 The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. ovarian follicle development The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus. biological_process GO:0001542 ovulation from ovarian follicle The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus. GOC:mtg_sensu https://www.ncbi.nlm.nih.gov/books/NBK279054/ biological_process GO:0001568 The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. blood vessel development GO:0042460 Wikipedia:Eye_development biological_process GO:0001654 The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. eye development biological_process GO:0001655 The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. urogenital system development Wikipedia:Kidney_development biological_process nephrogenesis GO:0001822 The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. kidney development biological_process GO:0001824 The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. blastocyst development biological_process GO:0001825 The initial formation of a blastocyst from a solid ball of cells known as a morula. See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. blastocyst formation biological_process GO:0001832 An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. blastocyst growth biological_process GO:0001835 The hatching of the cellular blastocyst from the zona pellucida. See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, zona pellucida ; EMAP:22' and 'TS5, embryo ; EMAP:23'. blastocyst hatching biological_process GO:0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. liver development placental development placentation biological_process GO:0001890 The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. placenta development fetal placenta development biological_process GO:0001892 The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. embryonic placenta development biological_process decidua development GO:0001893 Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. maternal placenta development biological_process vascular system development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. vasculature development biological_process GO:0001945 The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. lymph vessel development biological_process GO:0002520 The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. immune system development A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. organ system process biological_process GO:0003008 system process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. GOC:mtg_cardio A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. Wikipedia:Circulatory_system biological_process GO:0003013 circulatory system process A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. GOC:mtg_cardio A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. biological_process cardiac process GO:0003015 heart process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. GOC:mtg_cardio dph 2009-10-08T10:50:09Z cardiac valve development biological_process GO:0003170 The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. heart valve development dph 2009-10-08T11:14:21Z AV valve development biological_process GO:0003171 The progression of the atrioventricular valve over time, from its formation to the mature structure. atrioventricular valve development dph 2009-10-08T11:17:22Z biological_process GO:0003174 The progression of the mitral valve over time, from its formation to the mature structure. mitral valve development dph 2009-10-08T11:18:12Z biological_process GO:0003175 The progression of the tricuspid valve over time, from its formation to the mature structure. tricuspid valve development dph 2009-10-08T11:18:55Z biological_process GO:0003176 The progression of the aortic valve over time, from its formation to the mature structure. aortic valve development dph 2009-10-08T11:19:44Z biological_process GO:0003177 The progression of the pulmonary valve over time, from its formation to the mature structure. pulmonary valve development dph 2009-10-08T11:21:43Z biological_process GO:0003178 The progression of the valve of the coronary sinus over time, from its formation to the mature structure. coronary sinus valve development Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). biological_process response to abiotic stress response to biotic stress GO:0006950 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GOC:mah GO:0009552 biological_process gametogenesis GO:0007276 The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. gamete generation biological_process GO:0007292 Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. female gamete generation biological_process pan-neural process GO:0007399 The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. nervous system development Wikipedia:Neural_development CNS development biological_process GO:0007417 The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. central nervous system development biological_process GO:0007420 The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). brain development sense organ development biological_process GO:0007423 The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. sensory organ development GO:0007511 Wikipedia:Heart_development dorsal vessel development biological_process cardiac development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. heart development biological_process GO:0007517 The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. muscle organ development Wikipedia:Sexual_differentiation biological_process GO:0007548 The establishment of the sex of an organism by physical differentiation. sex differentiation Wikipedia:Gestation gestation biological_process carrying of young GO:0007565 The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. female pregnancy Attachment of the blastocyst to the uterine lining. blastocyst implantation biological_process GO:0007566 embryo implantation Attachment of the blastocyst to the uterine lining. GOC:isa_complete http://www.medterms.com The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs. giving birth egg laying biological_process GO:0007567 parturition The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs. ISBN:0198506732 The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Wikipedia:Coagulation blood clotting biological_process GO:0007596 blood coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. ISBN:0198506732 http://www.graylab.ac.uk/omd/ The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. Wikipedia:Hemostasis biological_process GO:0007599 hemostasis The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. ISBN:0198506732 The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. jl 2012-09-20T14:06:08Z GO:0023032 GO:0044708 GO:0044709 Wikipedia:Behavior behavioral response to stimulus behaviour behavioural response to stimulus biological_process single-organism behavior GO:0007610 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). behavior The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. GOC:ems GOC:jl ISBN:0395448956 PMID:20160973 The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. GO:0070261 biological_process hemolymph circulation GO:0008015 blood circulation The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. GOC:mtg_heart ISBN:0192800825 A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. jl 2012-09-19T15:05:24Z GO:0000004 GO:0007582 GO:0044699 Wikipedia:Biological_process biological process physiological process biological_process single organism process single-organism process GO:0008150 Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. biological_process A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. GOC:pdt The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. gonadogenesis biological_process GO:0008406 gonad development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. GOC:ems ISBN:0198506732 gonadogenesis GOC:cjm testicular development testis development biological_process GO:0008584 The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. male gonad development GO:0061039 biological_process ovarian development ovary development GO:0008585 The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. female gonad development Wikipedia:Fertilisation syngamy biological_process GO:0009566 The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). fertilization Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. GO:0002245 physiological response to wounding biological_process GO:0009611 response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. GOC:go_curators GO:0009795 embryogenesis and morphogenesis Wikipedia:Embryogenesis embryogenesis embryonal development biological_process GO:0009790 The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. embryo development embryogenesis biological_process GO:0009792 The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. embryo development ending in birth or egg hatching Wikipedia:Sexual_reproduction biological_process GO:0019953 A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny. Sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. sexual reproduction biological_process GO:0021510 The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. This term was added by GO_REF:0000021. spinal cord development biological_process GO:0021516 The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. This term was added by GO_REF:0000021. dorsal spinal cord development biological_process GO:0021517 The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. This term was added by GO_REF:0000021. ventral spinal cord development biological_process GO:0022414 A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. reproductive process The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. biological_process GO:0022601 The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. menstrual cycle phase The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. GOC:dph GOC:isa_complete GOC:jid biological_process estrous cycle process menstrual cycle process GO:0022602 A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. ovulation cycle process Wikipedia:Ovulation biological_process GO:0030728 The release of a mature ovum/oocyte from an ovary. ovulation development biological_process GO:0032502 A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. developmental process GO:0048590 biological_process growth pattern non-developmental growth GO:0040007 The increase in size or mass of an entire organism, a part of an organism or a cell. See also the biological process term 'cell growth ; GO:0016049'. growth biological_process GO:0040035 The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures. hermaphrodite genitalia development The series of events that restore integrity to a damaged tissue, following an injury. Wikipedia:Wound_healing biological_process GO:0042060 wound healing The series of events that restore integrity to a damaged tissue, following an injury. GOC:bf PMID:15269788 The beginning of the menstrual cycle; the first menstrual cycle in an individual. Wikipedia:Menarche biological_process GO:0042696 The beginning of the menstrual cycle; the first menstrual cycle in an individual. The beginning of the menstrual cycle; the first menstrual cycle in an individual. menarche The beginning of the menstrual cycle; the first menstrual cycle in an individual. GOC:curators PMID:16311040 Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. Wikipedia:Menopause biological_process GO:0042697 Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. menopause Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. GOC:curators PMID:18495681 The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. biological_process GO:0042698 The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. ovulation cycle The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. ISBN:0721662544 The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. Wikipedia:Menstruation biological_process GO:0042703 The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. menstruation The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. GOC:curators PMID:8693059 animal skin development biological_process GO:0043588 The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. skin development janelomax 2012-09-19T15:56:06Z biological_process GO:0044702 A biological process that directly contributes to the process of producing new individuals, involving a single organism. single organism reproductive process A multicellular organism process which involves another multicellular organism of the same or different species. jl 2012-09-19T16:06:16Z biological_process GO:0044706 multi-multicellular organism process A multicellular organism process which involves another multicellular organism of the same or different species. GOC:jl janelomax 2014-07-16T13:51:29Z Wikipedia:Menstrual_cycle biological_process GO:0044850 A type of ovulation cycle where the endometrium is shed if pregnancy does not occur. menstrual cycle biological_process GO:0046660 The establishment of the sex of a female organism by physical differentiation. female sex differentiation biological_process GO:0046661 The establishment of the sex of a male organism by physical differentiation. male sex differentiation Wikipedia:Organogenesis development of an organ organogenesis biological_process GO:0048513 Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. animal organ development embryonic organogenesis biological_process GO:0048568 Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. embryonic organ development post-embryonic animal organogenesis biological_process GO:0048569 Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. post-embryonic animal organ development biological_process GO:0048589 The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. developmental growth biological_process GO:0048608 The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. reproductive structure development biological_process GO:0048731 The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. system development biological_process GO:0048732 The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. gland development genital development biological_process GO:0048806 The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. genitalia development Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0050791 regulation of physiological process biological_process GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GOC:ai GOC:go_curators clotting biological_process GO:0050817 The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. coagulation Any process that modulates the levels of body fluids. biological_process GO:0050878 regulation of body fluid levels Any process that modulates the levels of body fluids. GOC:ai GOC:dph GOC:tb Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GO:0051869 physiological response to stimulus biological_process GO:0050896 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GOC:ai GOC:bf biological_process Mullerian tract development GO:0060065 The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. uterus development biological_process GO:0060135 A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. maternal process involved in female pregnancy biological_process GO:0060137 A reproductive process occurring in the mother that results in birth. maternal process involved in parturition biological_process GO:0060138 A reproductive process occurring in the embryo that results in birth. fetal process involved in parturition biological_process GO:0060322 The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. head development dph 2010-03-09T08:55:14Z biological_process GO:0061061 The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. muscle structure development dph 2012-08-22T17:47:53Z biological_process GO:0061458 The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. reproductive system development Any process that modulates a measurable attribute of any biological process, quality or function. regulation biological_process GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function. GOC:dph GOC:isa_complete GOC:mah GOC:pr GOC:vw Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. regulation of biological attribute regulation of biological characteristic biological_process GO:0065008 regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. GOC:dph GOC:isa_complete GOC:mah GOC:pr GOC:vw midori 2010-01-25T10:31:00Z urinary system development urinary tract development biological_process GO:0072001 The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. renal system development midori 2010-11-16T11:25:49Z biological_process GO:0072358 The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels. cardiovascular system development midori 2010-11-16T11:27:39Z biological_process GO:0072359 The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. circulatory system development