--- name: clinvar-variation-skill description: Submit compact ClinVar Clinical Tables and NCBI Variation requests for search, VCV, RCV, SCV, and RefSNP lookups. Use when a user wants variant-level summaries or identifier mapping --- ## Operating rules - Use `scripts/clinvar_variation.py` for all ClinVar and NCBI Variation work. - The script accepts `max_items`; for `action=search`, start around `max_items=10`. - For `vcv`, `rcv`, `scv`, and `refsnp`, omit `max_items` unless you need to trim nested arrays in the summary. - Re-run requests in long conversations instead of relying on prior tool output. - Treat displayed `...` in tool previews as UI truncation, not literal request content. - If the user asks for full JSON, set `save_raw=true` and report the saved file path instead of pasting large payloads into chat. ## Execution behavior - Return concise markdown summaries from the script JSON by default. - Return the JSON verbatim only if the user explicitly asks for machine-readable output. - Use `action=search` for the Clinical Tables endpoint. - Use `action=vcv|rcv|scv|refsnp` for NCBI Variation beta objects. ## Input - Read one JSON object from stdin. - Required field: `action` - Action-specific required fields: - `search`: `terms` - `vcv`: `vcv` - `rcv`: `rcv` - `scv`: `scv` - `refsnp`: `refsnp` - Optional fields: `params`, `max_items`, `max_depth`, `timeout_sec`, `save_raw`, `raw_output_path` ## Output - `search` returns `total`, `identifiers`, `display_rows`, `extra_fields`, and truncation metadata. - `vcv|rcv|scv|refsnp` return a compact `summary` and optional `top_keys`. - Use `raw_output_path` when `save_raw=true`. - Failures return `ok=false` with `error.code` and `error.message`. ## Execution ```bash echo '{"action":"search","terms":"VCV000013080","max_items":10}' | python scripts/clinvar_variation.py ``` ## References - No additional runtime references are required; keep the import package limited to this file and `scripts/clinvar_variation.py`.